LOCUS       DADVXV010000001        79205 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.001, whole genome shotgun sequence.
ACCESSION   DADVXV010000001 DADVXV010000000
VERSION     DADVXV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 79205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79205
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.001"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(154..279)
                     /locus_tag="KB969_000001"
     CDS             complement(154..279)
                     /locus_tag="KB969_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868024.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(413..1306)
                     /locus_tag="KB969_000002"
     CDS             complement(413..1306)
                     /locus_tag="KB969_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBB6868025.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(1488..2414)
                     /locus_tag="KB969_000003"
     CDS             complement(1488..2414)
                     /locus_tag="KB969_000003"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBB6868026.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(2499..3260)
                     /gene="pflA"
                     /locus_tag="KB969_000004"
     CDS             complement(2499..3260)
                     /gene="pflA"
                     /locus_tag="KB969_000004"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBB6868027.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(3504..5735)
                     /gene="pflB"
                     /locus_tag="KB969_000005"
     CDS             complement(3504..5735)
                     /gene="pflB"
                     /locus_tag="KB969_000005"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBB6868028.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6012..8462)
                     /gene="parC"
                     /locus_tag="KB969_000006"
     CDS             complement(6012..8462)
                     /gene="parC"
                     /locus_tag="KB969_000006"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBB6868029.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(8474..10519)
                     /gene="parE"
                     /locus_tag="KB969_000007"
     CDS             complement(8474..10519)
                     /gene="parE"
                     /locus_tag="KB969_000007"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBB6868030.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(10685..11119)
                     /locus_tag="KB969_000008"
     CDS             complement(10685..11119)
                     /locus_tag="KB969_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBB6868031.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11246..11884
                     /gene="plsY"
                     /locus_tag="KB969_000009"
     CDS             11246..11884
                     /gene="plsY"
                     /locus_tag="KB969_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBB6868032.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12016..12891)
                     /locus_tag="KB969_000010"
     CDS             complement(12016..12891)
                     /locus_tag="KB969_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBB6868033.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(12973..13764)
                     /gene="codY"
                     /locus_tag="KB969_000011"
     CDS             complement(12973..13764)
                     /gene="codY"
                     /locus_tag="KB969_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBB6868034.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(13782..15182)
                     /gene="hslU"
                     /locus_tag="KB969_000012"
     CDS             complement(13782..15182)
                     /gene="hslU"
                     /locus_tag="KB969_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBB6868035.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15196..15744)
                     /gene="hslV"
                     /locus_tag="KB969_000013"
     CDS             complement(15196..15744)
                     /gene="hslV"
                     /locus_tag="KB969_000013"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBB6868036.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(15781..16686)
                     /gene="xerC"
                     /locus_tag="KB969_000014"
     CDS             complement(15781..16686)
                     /gene="xerC"
                     /locus_tag="KB969_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBB6868037.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(16884..18260)
                     /gene="trmFO"
                     /locus_tag="KB969_000015"
     CDS             complement(16884..18260)
                     /gene="trmFO"
                     /locus_tag="KB969_000015"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBB6868038.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18229..20307)
                     /gene="topA"
                     /locus_tag="KB969_000016"
     CDS             complement(18229..20307)
                     /gene="topA"
                     /locus_tag="KB969_000016"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBB6868039.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(20429..21286)
                     /gene="dprA"
                     /locus_tag="KB969_000017"
     CDS             complement(20429..21286)
                     /gene="dprA"
                     /locus_tag="KB969_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBB6868040.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21342..22109)
                     /locus_tag="KB969_000018"
     CDS             complement(21342..22109)
                     /locus_tag="KB969_000018"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBB6868041.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22102..22962)
                     /gene="ylqF"
                     /locus_tag="KB969_000019"
     CDS             complement(22102..22962)
                     /gene="ylqF"
                     /locus_tag="KB969_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBB6868042.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23222..23620
                     /locus_tag="KB969_000020"
     CDS             23222..23620
                     /locus_tag="KB969_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6868043.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            23899..24399
                     /locus_tag="KB969_000021"
     CDS             23899..24399
                     /locus_tag="KB969_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6868044.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(24482..25033)
                     /gene="lepB"
                     /locus_tag="KB969_000022"
     CDS             complement(24482..25033)
                     /gene="lepB"
                     /locus_tag="KB969_000022"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6868045.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25185..25412)
                     /locus_tag="KB969_000023"
     CDS             complement(25185..25412)
                     /locus_tag="KB969_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBB6868046.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(25409..25927)
                     /gene="msrA"
                     /locus_tag="KB969_000024"
     CDS             complement(25409..25927)
                     /gene="msrA"
                     /locus_tag="KB969_000024"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6868047.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(25947..26660)
                     /locus_tag="KB969_000025"
     CDS             complement(25947..26660)
                     /locus_tag="KB969_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBB6868048.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(26663..27559)
                     /locus_tag="KB969_000026"
     CDS             complement(26663..27559)
                     /locus_tag="KB969_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6868049.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(27717..28559)
                     /locus_tag="KB969_000027"
     CDS             complement(27717..28559)
                     /locus_tag="KB969_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6868050.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            28691..29344
                     /locus_tag="KB969_000028"
     CDS             28691..29344
                     /locus_tag="KB969_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6868051.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(29407..29934)
                     /locus_tag="KB969_000029"
     CDS             complement(29407..29934)
                     /locus_tag="KB969_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6868052.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(29954..30901)
                     /locus_tag="KB969_000030"
     CDS             complement(29954..30901)
                     /locus_tag="KB969_000030"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6868053.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(30913..32799)
                     /locus_tag="KB969_000031"
     CDS             complement(30913..32799)
                     /locus_tag="KB969_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6868054.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(32959..35037)
                     /locus_tag="KB969_000032"
     CDS             complement(32959..35037)
                     /locus_tag="KB969_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6868055.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(35050..35325)
                     /locus_tag="KB969_000033"
     CDS             complement(35050..35325)
                     /locus_tag="KB969_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868056.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(35687..36142)
                     /locus_tag="KB969_000034"
     CDS             complement(35687..36142)
                     /locus_tag="KB969_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868057.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(36296..37504)
                     /locus_tag="KB969_000035"
     CDS             complement(36296..37504)
                     /locus_tag="KB969_000035"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBB6868058.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(37616..37948)
                     /locus_tag="KB969_000036"
     CDS             complement(37616..37948)
                     /locus_tag="KB969_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6868059.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            38096..38971
                     /locus_tag="KB969_000037"
     CDS             38096..38971
                     /locus_tag="KB969_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6868060.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(39053..39634)
                     /locus_tag="KB969_000038"
     CDS             complement(39053..39634)
                     /locus_tag="KB969_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBB6868061.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(39640..40899)
                     /locus_tag="KB969_000039"
     CDS             complement(39640..40899)
                     /locus_tag="KB969_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6868062.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(40901..41947)
                     /locus_tag="KB969_000040"
     CDS             complement(40901..41947)
                     /locus_tag="KB969_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868063.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(42182..42457)
                     /locus_tag="KB969_000041"
     CDS             complement(42182..42457)
                     /locus_tag="KB969_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBB6868064.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(42700..44010)
                     /gene="der"
                     /locus_tag="KB969_000042"
     CDS             complement(42700..44010)
                     /gene="der"
                     /locus_tag="KB969_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBB6868065.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(44192..45421)
                     /gene="rpsA"
                     /locus_tag="KB969_000043"
     CDS             complement(44192..45421)
                     /gene="rpsA"
                     /locus_tag="KB969_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBB6868066.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(45556..46236)
                     /locus_tag="KB969_000044"
     CDS             complement(45556..46236)
                     /locus_tag="KB969_000044"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBB6868067.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(46285..46920)
                     /locus_tag="KB969_000045"
     CDS             complement(46285..46920)
                     /locus_tag="KB969_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6868068.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(46986..48389)
                     /locus_tag="KB969_000046"
     CDS             complement(46986..48389)
                     /locus_tag="KB969_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBB6868069.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(48376..49407)
                     /locus_tag="KB969_000047"
     CDS             complement(48376..49407)
                     /locus_tag="KB969_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6868070.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            49438..49659
                     /locus_tag="KB969_000048"
     CDS             49438..49659
                     /locus_tag="KB969_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBB6868071.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(49824..50561)
                     /locus_tag="KB969_000049"
     CDS             complement(49824..50561)
                     /locus_tag="KB969_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBB6868072.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(50714..52054)
                     /locus_tag="KB969_000050"
     CDS             complement(50714..52054)
                     /locus_tag="KB969_000050"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBB6868073.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(52291..53814)
                     /locus_tag="KB969_000051"
     CDS             complement(52291..53814)
                     /locus_tag="KB969_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBB6868074.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(54192..54803)
                     /locus_tag="KB969_000052"
     CDS             complement(54192..54803)
                     /locus_tag="KB969_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6868075.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(54926..55051)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(55133..55849)
                     /locus_tag="KB969_000053"
     CDS             complement(55133..55849)
                     /locus_tag="KB969_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6868076.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(55855..56424)
                     /gene="scpB"
                     /locus_tag="KB969_000054"
     CDS             complement(55855..56424)
                     /gene="scpB"
                     /locus_tag="KB969_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBB6868077.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(56408..57205)
                     /locus_tag="KB969_000055"
     CDS             complement(56408..57205)
                     /locus_tag="KB969_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBB6868078.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(57175..57546)
                     /locus_tag="KB969_000056"
     CDS             complement(57175..57546)
                     /locus_tag="KB969_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6868079.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(57565..58452)
                     /gene="xerD"
                     /locus_tag="KB969_000057"
     CDS             complement(57565..58452)
                     /gene="xerD"
                     /locus_tag="KB969_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBB6868080.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(58548..59021)
                     /locus_tag="KB969_000058"
     CDS             complement(58548..59021)
                     /locus_tag="KB969_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6868081.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(59126..59989)
                     /locus_tag="KB969_000059"
     CDS             complement(59126..59989)
                     /locus_tag="KB969_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6868082.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(60185..62284)
                     /locus_tag="KB969_000060"
     CDS             complement(60185..62284)
                     /locus_tag="KB969_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6868083.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(62504..63613)
                     /gene="rpoD"
                     /locus_tag="KB969_000061"
     CDS             complement(62504..63613)
                     /gene="rpoD"
                     /locus_tag="KB969_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBB6868084.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(63637..65478)
                     /locus_tag="KB969_000062"
     CDS             complement(63637..65478)
                     /locus_tag="KB969_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBB6868085.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(65660..67975)
                     /locus_tag="KB969_000063"
     CDS             complement(65660..67975)
                     /locus_tag="KB969_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6868086.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(68160..69020)
                     /locus_tag="KB969_000064"
     CDS             complement(68160..69020)
                     /locus_tag="KB969_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBB6868087.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(69079..69600)
                     /locus_tag="KB969_000065"
     CDS             complement(69079..69600)
                     /locus_tag="KB969_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBB6868088.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            69878..70639
                     /locus_tag="KB969_000066"
     CDS             69878..70639
                     /locus_tag="KB969_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6868089.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            70665..73256
                     /gene="mprF"
                     /locus_tag="KB969_000067"
     CDS             70665..73256
                     /gene="mprF"
                     /locus_tag="KB969_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6868090.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(73444..74631)
                     /gene="tuf"
                     /locus_tag="KB969_000068"
     CDS             complement(73444..74631)
                     /gene="tuf"
                     /locus_tag="KB969_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6868091.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            74999..75355
                     /locus_tag="KB969_000069"
     CDS             74999..75355
                     /locus_tag="KB969_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6868092.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(75596..76600)
                     /locus_tag="KB969_000070"
     CDS             complement(75596..76600)
                     /locus_tag="KB969_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBB6868093.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            76766..77617
                     /locus_tag="KB969_000071"
     CDS             76766..77617
                     /locus_tag="KB969_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6868094.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            77634..77879
                     /locus_tag="KB969_000072"
     CDS             77634..77879
                     /locus_tag="KB969_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868095.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            78066..78770
                     /locus_tag="KB969_000073"
     CDS             78066..78770
                     /locus_tag="KB969_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868096.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT        21840 a        16640 c        13615 g        27110 t
ORIGIN      
        1 aaaagcattt tgaagcctga ctattacgac ttcataaatg cttttttagt tttaaacact
       61 tcaatctaaa agaataaccc aagattggat aaattattaa tgactcgcca ttcgtttctt
      121 agtgattctg gattatcaaa tggacttcct aatctaatca gctagttctt cccataaaat
      181 gccatacttg actgaatcat aatattgatt atttaaaaat ctaacttttc ttatcactac
      241 ttcctttgtc attccacatt tctcaccatt tttttgcatt cctttgtttc cagaccatgt
      301 agtgaatcta ataggtggta gataggcaaa atactcaaat aattctttta accataaagg
      361 aagagaaagg ctcctcctgc aagagtcagt ataatttttg cttactgctc tcttaggttt
      421 tactcactaa aactgttcca tattctttga tataagaaaa tgcatgcggt ataaatttct
      481 tgctcagctc agaaaagatt tgtcgtttaa gaaaggccat ttcctccatt gtcaatgaag
      541 gatccaatgt tggtaattca atctcaaaat tgtttttttc gacaataggt aattctaatg
      601 tgaatgattc ttcttccttt atagtattcg tcacaagtag agactgatgg aaaatactag
      661 gccggcgatt tttatattta ttcttacgta tcctgtcaac gataacttct atttgatcaa
      721 aaaagtacga ttcatttacg tctccaataa gttcggctaa ttctttgaat gccttcgtta
      781 caggaagctg attcttctgt acaaaaaagt aattagccaa agtaagcggg aagtgttcta
      841 tagaggaaag tgtgataaaa cggtacttct catttcctgc agttgtcctc agcaattctg
      901 tctctcggct gtttcttact ccataaaaat acgcttcttt ccgttcatct tcgaaacaat
      961 acgcccaaat aacttctccc atcgctaatt tttgttcatc aacagagagt ctcttcaatt
     1021 gttcagctat ggtttcagca gccgaagtgg cttgttgcaa gtaatcttta ggatcaaata
     1081 ttggaaagtt caaatgatat cttcgttctt ccctcttgat taatcctgca tcgatcaata
     1141 aatcaagaaa atgggaaaat ttattttgcg aaaattcttt tttcaattct cttagaatcg
     1201 tttcttgttc tcgatgttca tatagataat cggtcaatga agaaaaaagc ggatcatcgg
     1261 tcagtttttg ataaaagttt tccttatttt ttgaataata gttcatatat gttctctttt
     1321 ctatccgttt tattttactt aaaaggcttt tacgtaaaaa ggaggaagaa caagagtcat
     1381 aattgactgt tattctcctc catttcttcg gcctttagta tgttctatgt ttctttttat
     1441 atcaatcgct tatccattca ttttgaatgc ttcatactac catttgatta gctaaataca
     1501 gccgtcaatt gaggtacgac ttgtttttta cgtgaaacga cacctttaag caaagcacgg
     1561 ttgttggtca aagttgtttg gaaagcttct tctacttttt cttttccttt accagcaaca
     1621 agtaattctg aatcactgtc taagatgttt gtgacaacta atacgaacag atcgtagcca
     1681 tttgctttca tttcatcttc cattgctgct tctagctctg cttgtcgatc catcacttca
     1741 ttaaggtcca ctgtattgac ttgagcgata cgaacgttgg aactgcccat tgggaaactt
     1801 tttgcatcca aatcaagaag aaccgcagct gatttatcac ttagatttgt tcctgctttc
     1861 aacatttcaa gtccataagt gtttagatcg acttcagcga ttgctgcaag ttcttttgca
     1921 gctgcttcat cttcaggcgt acatgttggt gatttgaaca acaatgtatc tgaaatgata
     1981 gctgagagca tgattcctgc gatttcttta ggaattgtta cttggttttc tttatatagt
     2041 tttaaaataa tcgtacttgt acatccaact ggttctgcac gatagtacaa tggattagct
     2101 gtttcaaagt ttgcaatacg atggtggtct actacagcta aaatatttac ttcgctgata
     2161 tctgaaatac tttgttggaa ttcattatga tccacaagca tgacatctgc attttctgct
     2221 ttagctgact ctactactcg tggtgcagat agctgaaagt ggtctaatgc gtattgtgtt
     2281 tcttcattag gtgtacctag agcaactgct tctgtttctt tacctaattc attttgcaag
     2341 tgtgaaaacg caatggctgc cccgattgca tctgtatctg gattttggtg accaaaaact
     2401 aaaatttttg acatgtcatt cgctcctttg tgatttctcc tatttaataa tagcaaaaaa
     2461 acggaaagaa gcaatactta tcttctttcc gatgcgacct atcgcgttaa atattttgta
     2521 tactcttctg tatgaagcaa tcgtttagca ttttcgacac gttcttttgt aggtggttcg
     2581 atcccttcta atggatattt caaaccaagt gtttcccact tgtattttcc catcgtatga
     2641 taaggaagaa tctctactct gtctacattt gacaaggttt gaataaagtt gtctagtcgg
     2701 atcaaatatt catcataatc acttcgctca ggaactagta catggcgaat ccaaaccggt
     2761 ttgttgattt ttgacaaata ttgagccatt tctaaaatat tttcattgtc ccaatgcgtt
     2821 agttttttat gctcttcatt atcgatgtgt ttgatgtcaa ataacagtaa atctgtatac
     2881 ttcatcaatt cttgaaaacg tgaaaagaaa ggttcttcat acgtaaaagg ttttccgcat
     2941 gtatccaatg tagtatgcat cttccgctct tttgcttttt taaatagttc gatcaaaaaa
     3001 tcgatctgca atagaggttc tccaccacta acagtaatac cacctttatc tccccagtaa
     3061 ggtctgaagc gttctgcttt atctaaaagt tcatctgctg tgtattcttt ccctccgcca
     3121 atattccaag tatctggatt gtgacaaaat tggcaacgca tgcggcatcc ttgcataaac
     3181 acgacaaagc gcagtccagg tccgtctact gaaccgaaag tttcgataga atgaacatag
     3241 ccgattgttt tttcttccat ttaagttcac atcttttctt tgatttcatt ttaagtacaa
     3301 gttagctgtc gaagcgaagc tttctgaaca aaatttttcg caattgccgc ttcgttatgt
     3361 gtaaaattta cagggacgga acatacaagt cctgcccctg taaatcgttt ctttcaaata
     3421 agcatactga ttattcgatt ttgatgcgat ggctattcaa cgtcctttcg acgctaagtc
     3481 gaaaaacttt tttcacgaac tttttacatt ctgtcgtgtg aagttctcat caagacatct
     3541 aattgttgtt ctcttgtcaa gtcacggaat ttaactgcat aaccagatac ccggatcgtc
     3601 aagttcggat atttcattgg attttccatt gcatcacgca ataaatcatt actgaataca
     3661 ttgacattca aatgataagc tccttttgag aagtatccat ctaagacatt acgcaagttt
     3721 tcgattcttg tatcttgttc ttttccaaga cctgaaggat tgattgtttg ggtatttgaa
     3781 attccatcca atgcacagcc gtaattcatt ttagctgttg agttcaggct agctaataac
     3841 ccactttgtt ccgcattgta acttggattt gctcctggcg caagtggttt tccagcttca
     3901 cggccatcag gagtatttcc tgtattttta ccgtaaacaa catttgaagt aatcgtcaat
     3961 aatgaagttg ttggttttga gttgcggtaa gttttatgac gtttgatttg tcccatgaag
     4021 tattccaaga tccatgaaac taattcatct gcacggtcat catcatttcc gtatttaggg
     4081 aagtcgccat ccacttcaaa atcaactgct attccttttt cattacggat tgcttttact
     4141 tttgcatatt tgatcgctga caagctgtct gccgcatgag agatcccagc aatacctgta
     4201 gcaaatgtgc gttgcaagtc agaatccatc aaagccagct gagctgcttc ataagaatat
     4261 ttatcatgca tataatgaat gatgttcaac gtattgacat atagttctgc taaccaatcc
     4321 atcatattca tgaagttatg tttcacttct tcaaagtcta gtatttctga tgtgattgga
     4381 cgatattctg gtccaacttg ggcgccagtc acttcatcga ctccgccatt gatggcatat
     4441 aatagtgttt tagccaagtt agcacgagcg ccaaagaatt gcatgtcttt tccgacaact
     4501 gttcctgata cacagcaagc aatcgcacaa tcatcagaac cccattgttc acgaagctga
     4561 ttatcatttt cgaattgaat cgaagaactt tcgatagcga ttctgctagc atatgttctg
     4621 aatccttctg gaaggtgttc agaatacaaa acagtcaagt ttggttctgg tgaaggtccc
     4681 atatttgtta atgtatgaag cagacggaaa tcattctttg taactaatga acgaccatct
     4741 aatcccatac ctgcaatgga taaagtagcc cagataggga atcctgagaa taattggtta
     4801 tattcaggtg tacgcgcgaa tttgaccata cgtaatttca ttactaagtg gtcgatcaat
     4861 tcttgtgctt ctttttctgt gattactcca ttatccaaat cacgttggat atagatatca
     4921 aggaatgctg agatacgtcc gattgacatc gcagcaccat tttgtgattt gattgctgct
     4981 aaatatccga agtatagcca ttggacagct tcttttgcat ttgcagctgg tttagaaata
     5041 tcatagccat atttcgcagc catttctttc atttgcgcta atgcacgata ttgttcagtg
     5101 atttcttcac gtaaacgaat cacttcttca ctcattgtat gataaccagt catatcatga
     5161 tcttttttct tttgttccat caaatagtcg attccataca atgccacacg acgatagtca
     5221 ccgatgatac gtccgcgacc gtaagcgtct ggaagccctg taatgatttt gtttttacga
     5281 gcagcacgca tttcagcagt ataagcgtca aatacacctt gattatgtgt tttgcgccag
     5341 tcagtgaaaa tatgtgtcaa ttcatcgttt ggtgtatagc cattgctttt tagcgcattg
     5401 ttagccatat tgattccgcc gaacggcatg aatgcttgtt tcaaaggttt gtctgtctgt
     5461 agaccgacga ttttttccaa atctttatcc aaatagcctg catcgtgtga agtaatagtt
     5521 gatacgattt ctgtgtccat atcatagaca ccgttacgct cgaattggat atcatttaac
     5581 ttttgcaatt catcccataa tttttctgtt gcttctgttg ggccttccaa aaagctgtca
     5641 tcaccgcgat attcagtgta gttattttga ataaagtctc tagtgtctac gccttctttc
     5701 catttggtac ctttaaatcc attccattgc tccattgtat ggacctccta aatttctgtt
     5761 ttatgtaaca gtttttacgt gattagtata acacagcacc ctatctttgc aagggttttc
     5821 ttgtttttta tttaacaatt tttatgtttt atttacatat atttaaatca acgttgacat
     5881 accaacattt aagcattgtg aacactttca tctttttttg caaacgtata aggatttatt
     5941 aaaaatgaat gaaaaagaga cgccacctgt attaatacag atggcgtctc ttcattaaaa
     6001 tactacaaca gttacgactc gatgaaaatc tcaggagcat cgataacttc gatgacttct
     6061 ccaccttttt tctcatccat cgcaaatgat ccattcgatg ttcgatcacc tatagggaaa
     6121 tcagttgggt caatcgttaa ctgctgccct ttttgattca tcaaggttat ttcttttgat
     6181 cttccttccg acatatagat aatacggtgc ggattttttt tcagctcacg catgaccgtc
     6241 actccccgct tcgcacgtga agtttggctg atttcttgag caagcatgcg tttaacagct
     6301 cctcgctgag taacgattac gatcggcgta tcaccttctg ctaacacaag cagcccgttg
     6361 ataatcctat ctccatcttt caaattcata gacttcactc cagctgcctt tgctccaaca
     6421 acgggaacat ctgttaaagg atagcgcaaa cccattcctt gatgcgttac taagaaaaca
     6481 tctaagcctg gctgatcttc tttcagatac acagcaatca gttcatcttc ttccgccttt
     6541 agcttcatac agctgagcgg acggctctta taggtgcgcc atggttcgaa ctctgtcatt
     6601 cgtgtttgct tgatcaatcc attcttgctg atgaatacaa atgttttctc tgcttgaatt
     6661 ttttgatatg ggaaaacagc taaaatcgat tcgtctacag acagattgga gattgtttga
     6721 gaaatgtgct caccagcatc tttccatttc aaatcgggta gttcatggac agggcggtag
     6781 atcacatttg ctttatttgt gatcagaaga acatggtcca atgtactcaa ttcacctgag
     6841 tatagcaagt agtcgccttc tcgcatcccg atttcttctg gtttggaagc actataagaa
     6901 cgaaggcttg ttcgcttcac atagccttct cgcgtcacac tgacaattac gtcttcttgt
     6961 gccactaaga cttgcgtatc aattttgatt tcttcgattt cgtcttcgat tgtcgttaga
     7021 cgagcggaag aataattttt tttcacttct cgcaattctt ttttcataac agagaaaagc
     7081 tctttgtcat ttgaaaggat tttattcaac tctgtgattt gcgcaatcaa gctttcggat
     7141 tccttttgaa gctctgtgat atccgtgttc gtcaaacggt ataattgcaa tgtgacaatt
     7201 gcttctgctt gttcttctgt aaattgaaag acgtcgacta aattcttttt ggcgtctttt
     7261 ttgtctttac tttcacgaat cgttgcgatt acttcatcca gaatcgataa agctttcatc
     7321 aatccttcta cgatatgctg tcttttttga gctttggcta aatcgaattg actacgtttt
     7381 gttatgactt gctttcgatg ctcgatataa cttcttaaaa tgtctttcag tccaacttga
     7441 tgcggagtca tatggtcgat agcgaccata ttgaaattgt aattgatctg tagctcagtg
     7501 tttttgaaca aataattcaa aattccttga gcattggcgt cttttttcaa ttcgacgaca
     7561 atttgcagac ctgttctatc actttcatct cgtacttcag ctattccatc gattttctta
     7621 ttcaaacgga tctcatccat ttttttcacc aaggtcgctt tatttacttc atatgggatt
     7681 tctgtgatca cgatttgctg tttattaccc ttcattgcct ctatctttgt tttcgaacga
     7741 agaataactt ttcctcgtcc tgtttcataa gcttttttga tttcatcttt tccttgcaag
     7801 atccctcctg ttggaaagtc aggtccagga atatattcca tcaatttttc aaggctcgct
     7861 tgtggatgat cgatcatata gattgtgcca tcgatcactt cagctaagtt atgagtcggg
     7921 atttctgttg catatccagc agatatacct gtcgatccat tgacgagaag gtttgggtat
     7981 cgagctggaa ggactgttgg ttctttttct gtatcatcaa aattccacac gagatcgact
     8041 gtttctttct cgatatctgc tagcatctct ccacttaact tggataatct ggcttcagta
     8101 taacgcatcg cagcaggtgg atcaccgtcc atactcccgt tattcccgtg catttcgatc
     8161 agtacttccc gcaacttcca gtcttggctc atgcggacca tcgcttcata aatactgatg
     8221 tcaccatgag gatgataatt ccccatgata tttccgacag attttgctga tttacggaat
     8281 cctttgtcat acgtattgcc atctttgttc atggcaaata atatccggcg ttgcactggc
     8341 ttcaatccat cacggatatc aggcagtgca cgttcttgga taatatattt ggaataacgt
     8401 ccgaagcggt cacccatcac ttcttctaaa gttaattctt gtacttcttg tcgattttcc
     8461 atcaggtgac ctcctattct acttcaaata actgattgtt ttcattttta tctgctcgtt
     8521 cttcatctaa taaatcatta gaaactgaag gagagatttc agtatcctct tttttatcta
     8581 agatactgcc atcttcttcg agcgtaaatt gcacgtgatt ttcgatccat tttcttcgag
     8641 gttctacttt gtcacccatc agtgtggtta ctcgacgttc agcttgcgca gcatcatcga
     8701 tacggacgcg gatcaacgta cgggaagtcg gatccatcgt tgtttcccac aattgttccg
     8761 cattcatctc tccaagtcct ttatatcgct gcagcatata tcctttgccg acttttttaa
     8821 tcattgctgc caattcgtca tctgtccacg catattcaat gacttgcttc tttccttgtc
     8881 ctttggatac tttatataaa ggcggtaacg cgatatatac tttcccagct tcaatcagcg
     8941 gtttcatata acgataaaag aaagtaagca gtaatacttg aatatgggcg ccgtctgtat
     9001 ccgcatcggt catgatgatt actttgtcgt aattacagtc ttcgatagaa aactcaggac
     9061 cgactcctgc accaatcgta tagatcatcg tattgatttc ttcatttttc aagatatctt
     9121 gcattttagc tttttcggta ttgatgactt ttcctcgtaa aggtagaatt gcttggaact
     9181 ttctgtctct tccttgttta gcagatccgc cagcagaatc cccttcgact aaatacaatt
     9241 catttttctt agggtttcgg gattgtgcgg gtgtcaattt tcctgaaaga agagattcgc
     9301 cttttttacg cttcttccca tttcggcttt cttctctggc tttacgtgct gcttctctcg
     9361 cttctctggc tttgattgct ttacggacca acatctggct catttcgcta ttttcctgca
     9421 aataaaagcc catttgttca ctgatgacgt tatctactac ggtacgagca actggcgtac
     9481 caagtttttc ttttgtttgc ccttcaaatt gcagaagatt ttcaggtaca cggatagaaa
     9541 gtacagcagc taacccttct ctgaaatcac taccttccag attcttgtcc cgttctttca
     9601 gcaaaccaac ttttctcgca tattcattat aagatttcgt catcgccgct ttcataccag
     9661 cttcatgggt tcccccatct tttgtccgaa cgttattgac aaaagataaa acattttctg
     9721 aataaccgtc attgtattga taagcgacct ctacttcgat accttctttt tctcctgaaa
     9781 aataaacaac tggtgtcaat gtatcttttt cttcattcag ataatcaaca aattctttga
     9841 ttccttcttc gtaatgaaaa atttccttga ctggttcttc tccacgaaga tcagaaagag
     9901 agattttaac gccttttaga agaaaggcag attctcttaa ccgttcggct aaaatttcat
     9961 atgaaaattt cgttgtactg aatattgtat catctggtaa aaaatggaca gtcgtcccgt
    10021 ttgctttttt tgtttttcct atctttttca aagtaccgtc aggtttaccg ccgtttttaa
    10081 atttctgctg atactctacg ccatctctaa cgatcgttac aattagccat ttcgataagg
    10141 catttaccac actggctcct acaccgtgca gtccaccaga agttttgtac cctccttgac
    10201 caaactttcc gccagcatgc agcacagtaa aaatcacttc aactgttggt attccggaag
    10261 catgcattcc tacaggcatc ccacgtccgc tatctgcaac agttatacta ttgtcttcat
    10321 ggatggtcac atcaatctca ctgccataac ctgataatgc ttcgtcaact gcattatcga
    10381 cgatttcata gactaaatga tgcaagcctc ggctgtcagt ggatccaatg tacatccctg
    10441 gtctttttct aactgcctct aatccttcca atacttggat ggacgagtca ttgtattcgt
    10501 tgtttacttt ttttgccaag gcaaacgctc cttcaataat actttgcggc aaaaccgcac
    10561 cacgattatc atactagaaa aggtcgtgaa aaaaaagagg gtagacgaga aatcaatttt
    10621 aattatctcc taaccgcttt ttcgacattc ccctctatcg atcatctctt ctttgtggtc
    10681 atttttattt ttggttttct ttcaacttac caagttcaat cttaatacaa cgatccatta
    10741 cgatatctgt acgtcctgct tttcttagca tctcagctgc ttctttgttt tcaatcccta
    10801 attgtgccca gaacacttta gcatcagttt tcaaaaaatc acctgctatt tcaggtaaaa
    10861 attcactccg tctaaataca tctacgatat cgattggatc atcgatttct gtcaaattcg
    10921 catagacttt ctcgcctaga atttcttcac cagccaataa tggatttact ggtatgattt
    10981 tatatccatt gtcttgcaat acctgtgcaa ccatgtaact tgttcgttct ggtttattgc
    11041 tcaagcctac gacggcaata ttttttgctt cttccaaata gttgaaaatc gtttcttgtg
    11101 ttggattttt tacagacatt tctgccaccc cttgcttttc tttttattcc atctattata
    11161 cttgtatctt tcattttttc aattgttcct gttacctatt catgctaaaa taaaggatag
    11221 ttttcaactt gaaagagggt aaaaaatgaa attgatctta ttacttattt tagcatatct
    11281 tttaggttct attccttccg gtgtctggat tggcaaattg tttttcaaaa aagatatccg
    11341 acaacacggg agcggtaata ctggaacgac caatacattt cgtgtattag gcaaaacagc
    11401 cgggattgtt gtcctgctta tggatatttt aaaaggtaca ttggctactt gtttgccgat
    11461 gatcttccac ctttctggga ttaaccctct ttggtttggg gtatgcgcca ttcttggcca
    11521 tacatttccg atttttgctg ggttcaaagg aggaaaagct gttgcgacaa gtgcaggaat
    11581 gcttttagga tttaatcctg tattttttgt ttattcttgt atcatcttta tcgttagttt
    11641 attttgtaca agtatggtga gtttgagcag tatgatcagt gcagtattga tcactttatc
    11701 tacgatcgtc cttccttatg tagctcctgt gattttggct aagcccaatt ggttactgac
    11761 gatcattgcc tttttagttt cttcctttat cttttatcgg cataaagaca atatcaagcg
    11821 tatcagaaac catactgaaa gtcgaatccc gtttggtttg aatagcagca agaaaaaatc
    11881 ctgatacttt ttcattccaa agagataaaa cgggagtgtg acaaatcgat gtcacactcc
    11941 cttattactt acaggatagc ttttttacac accttggtaa acggtgttcc ctgctaactt
    12001 ctcggtcaca acctcttact tcactgtgat ggaatatttt gtcttgaaga tttcatgggc
    12061 acctagttga ttgatcccta ctttttccat caagtttcca ctactgttca ccgtgtcagc
    12121 gattccgcac cacggttcga tacaaacgaa aggcgcttct tttggataag gagaccagat
    12181 ccctacataa ggcatatctt tatagcttaa agttacgcta tgggaagatt tttcacttcg
    12241 aatggcgtac gcatttagac cccttgtttc aaaaaccaag gcatcttgct caaaaagttc
    12301 acgattcaaa gccagattcg tatttgtctg acctaacgtc ttttgatcca tatcgatgaa
    12361 tgggcctttc aatggtaggc gtaatcttga tttcaatgga gaaaatgcca gatagaaatc
    12421 ttcaaatgac aatccttctt caagaggtac attgaaagca ggatgtccac cgatagaaaa
    12481 gaacatttct ttttcaccgg tatttgccac ttgataatga accgtgatgc cgtctcctcc
    12541 taattcatag ctgatcacta attcaaaatc aaatggatac ttttctaatg tctccggcgt
    12601 actccttaag atgaaactag ccatttcttg tccatgttca atgacttcaa aatccatatc
    12661 ccgagcaaat ccgtgttgcc ccatttgata tgttttccct tgataaacat actgatcatc
    12721 ttttaaacgt ccaacaaaag ggaataaaac cggtgcatgt ctgccccaat acgctggatc
    12781 accttgccag atatactcta aaccatgttc ttttgatttc agactgatca attccgcacc
    12841 gtgttcagcg atttcggcga tcagctggtc attttgaata ataacagtca ttgccattcc
    12901 tccaacttcg acttactttt taaaatggga aggctggaac aaacatttct atctgcccca
    12961 gtccccttac ttctaataac tgtgttttgc taactcgtct ttaaaacggg aattcaatac
    13021 ttttaaataa gttcccttca tgcctaacga acgagattca atgattccag ctgattccaa
    13081 ttttcgtaaa gcattgacga tcacagaacg agtgatgccg atactatcgg caatattaga
    13141 agcagtcaga cgaccttcat ctccatccaa tgcttcaaag atagcttgta cagccttcaa
    13201 ttcgctataa gataatgtgt tgattgccat ttggacagcc gttgcactcc gtacatctgc
    13261 ttcgatgctt cgagacttct gataaaggat ctgcataccg acaaccgtag ctccatattc
    13321 tgctaagact agatcgtcat ctgcaaacga ttgttccata cgagataaga taatcgtacc
    13381 caaacgttcg ccagctccaa agatcggaac gacagtcgtc agaccaaatg gatatttctc
    13441 tcttgactct accggaaatg cagtaatatc actagtaatt gggatattag cttcagtttt
    13501 catcaactgt gccactgtat cagtataaga ttcaggaaat tgtttctcaa caaacattgt
    13561 tttgattcgt tcattgttca catcgtgacg ttcattataa cctagtaata ctccgtcact
    13621 tcctatgata taggtgttgc tgtcaagaat accacctagt gtgacagcca ttttatcgta
    13681 aggcaaatct gcttgcatgt caaaagtatt cttttgctgc aaaagtgtgt ttatcttgcg
    13741 ggttttcgtt agcaagtctg tcattgtcgt cctccgattt tttataaaat atagcgactt
    13801 aaatcttcat ttgccgcaat tgagccaagt ttgtcatcca catatgcttc tgtgatcgtt
    13861 atttctccca tttgcatatc tggtgcttca aataatagat cttctagtag tttttccaaa
    13921 atggtatgca gtctgcgtgc gccgatatta tctgtgtcac ggttgacatc gaaagcgatt
    13981 tgagcgatcc gttcaattgc ttcttttgta aacgtaactg acacattttc tgtaccgatc
    14041 aacgcgacgt attgttttac taaagcatta tttggttcgg tcagaatctt cacaaaatct
    14101 tcagctgtca aatcatctaa ttctacccgt atcgggaagc gtccttgaag ttctggaatt
    14161 agatcacttg gtttagacaa atggaaagct cctgaagcaa tgaataggac gtgatctgtt
    14221 tggatgatcc cgtattttgt gtttacttgt gaaccttcga caattggcaa tatgtctctt
    14281 tggacgcctt ctctggatac ttctccagat tgctgtgatt tagaagtgat cttatcgatt
    14341 tcatcgataa aaataattcc actttcttcc gctaatttga ttgcctcact atggatatca
    14401 gcatccttga ctaattttgc tgattcttcc ttgatcaata actctaaagc ttctttgact
    14461 gttaccgtcc gttccacttt tttcttcggt gtcaaagcac ctagagtttc atttaggtcg
    14521 atccccattt gctccaatcc attgttcatc attggtgcag gtttcttttg gtcttcaact
    14581 tcaatggtta cttcacgact atccagtaaa cccttttgta gttgttccaa gactgtacgg
    14641 cgattgattc gaatatcttc tgtcacttct tcttgcggtt cagcggtatt ttgctgacta
    14701 gcattaaaaa gattcatcat ttgttcaaat tgattagtgg attgtttctg ttcttttttg
    14761 ataccaggta ccaagatttt taccaaacgt ttttctgcat tttttttagc acttgtgtat
    14821 acacggctgt actgctcttt ttctacgatt tggatcgcat tttctactaa atcccgaacc
    14881 attgattcta catctcttcc gacataaccg acttcagtaa attttgttgc ttcgactttg
    14941 acaaatggtg cattgacgat ttttgccaaa cgtcgtgcga tttctgtttt accgacccct
    15001 gtaggtccga tcatcagcat attttttggt gtaatatctt gttgcatttt ttcatctaac
    15061 tgcaaacggc gatagcggtt acgcaaagca acggcaacag atttttttgc tgcgtgctgt
    15121 cctacgatat attcatctaa ttcacttacg atttgtcttg gtgtttgttt taattcatac
    15181 atatctactc acctcttaca gttcttctac gataatatta tgattagtaa agatacagat
    15241 atctgcggca atatttaacg cattttctgc aatttctttc gcactcatgt cgttttgagc
    15301 atagtttttc attgctcggg ctgcagccaa cgcaaaattc cctcctgatc cgatagctaa
    15361 gataccatca tctggtgtga taacttctcc tgtacctgaa acaagaagca tttctttatc
    15421 attcattacg atcagcatcg cttcaagttt ttgcatagat tgctgtgtcc gccattcttg
    15481 agctaattcg acagctgcgc gttgtagatt cccgttatat tcgtttagtt tgccttcaaa
    15541 tttttcttct aaagtaaacg catctgcaac acttccggcg aaacctacaa caacttctcc
    15601 attgtagata cgtcgtactt tctttgcagt gcctttcatg acaacagatt cacccattgt
    15661 tacttggcca tctccagcca tagcaaattt cccgtctttt tcgacggcac agatagtggt
    15721 tgaatgaaat ggtgattcga ccatgtttgt ttcctcctaa atttgttctt ttccttattt
    15781 ttacgctctt ggatggaaag aacgatagtt tttttgtaaa ctttcttttg ttacatgggc
    15841 atagatctgg gtagtcgata aattggcatg tcctagcaat tcttggactg tccgcaaatc
    15901 tgccccatta tttaataaat gagtagcaaa tgtatggcgc agcatgtgag gatggatatc
    15961 actatccaaa ctgctttttt tgatcatttg attcaagaca tattcaattc cagtaggcgt
    16021 gattggtttt ccatgatgat tcacaaaaac gatatcatgc tcttcgtgat attttgtcat
    16081 caatacctgg cggccttccc tgaaatattc ttgcagagca tcttgagcaa aagaacctag
    16141 aggagcatat ctctctttgt tccctttacc atggatcaac atgacctctg aatcaaaatc
    16201 aatgtctgat accgacaaac tgctacactc acttaaacgg atgcctgacc cgtaaaggac
    16261 ttccagtaaa gcgcggttcc tcaaatccaa aggactatct cctgctacgc tgtcaaaaag
    16321 tgcttgcatt tcattttcat aaaaaaaacg tggcagtctc aaatttttct ttttgagatg
    16381 aacgtaagaa aatggatttt cttttatcac ttcttctttg agaagatact gataaaacga
    16441 acgtaggctg gctatcttgc gactgataga atttctgcta tagctaggac gatgatcagc
    16501 taatgcactc aaatagacac gaaccgtaaa atattccgcc ttcagcagat cagcgtctcc
    16561 agattcctcc aaaaaatgtt tgaaatggag aatgtcttct tcatatgctt ctttcgtttt
    16621 ttctgaatat cctctttcga caatcaaata acgcaaaaat ttttgttccc acgtggcttc
    16681 tgtcattttc tcaccttcct tttgtcccag agaataattt agcacagcgt ttataaaaag
    16741 acaaataaat tgtcagaatt taaccaatat ttctaagttt gttcacaatt ggcgcaattc
    16801 ctcacatttt gtttgagaaa ttcttaagaa aaacgcaaga aaaagagcga gactatccgt
    16861 ctcaccctct tcatggagtt tccttactca tttgggattg cagttttttc taattctgtt
    16921 tttattgcct cattagcttt taaagctcgt tgtgcaattg cttcatatct tgcttttttg
    16981 tctcgaatgc gctctggcag ttcaggaaac agaccatagt tggcattcat cggttggaaa
    17041 tgttttcctt ccgcatgagt aatgtagtaa gccatacttc caatagctgt ttcttgtgga
    17101 aactcgactg gttccatttc ttttgctaag cgtgcggcgt tgattccagc aagtagtccg
    17161 ctcgctgcac tttcaacata gccttctaca ccagtcatct gacctgcaaa gaacagatct
    17221 tcgcgtttcg ttgattggta agtcggtttc agcaattctg gcgaattcat aaagctgttt
    17281 cggtgcatca caccatagcg aacgaattca gcattttcta acccaggaat catccggaaa
    17341 acacgttttt gctcgcccca tttcaagtga gtctgaaagc ccacgatgtt gtataaagaa
    17401 gctgcagcat tgtcttgacg cagctggata acagcataag gacgtttgcc agttttagga
    17461 tcttccaatc caactggttt cataggtccg aaaagcatcg ttttgaatcc tcgctgtgcc
    17521 attacttcaa ttggcataca tccttcaaaa tatttttctt tctcaaaaga tttaagttct
    17581 gccacttcgg cattgattag tgcctcatgg aaagctttga attcctcttc tgtcatcgga
    17641 cagttcaagt aagctgcttc tcctttgtca tagcgggact tcaaatatac tttatccata
    17701 tcgatcgtag ctttgtctac gattggtgca gctgcatcat agaaataaaa accatctgaa
    17761 ccattgaatg ctttgatgct ttctgctaat ggatgagaag tcaaaggtcc tgttgctact
    17821 acggtgattc cttccggtat ttcagtaatt tcttcgttta tcactgttac taatggatgc
    17881 tctttgactt ttcgggtaat tgtttcagaa aaagaatcgc ggtcaacagc taaggcacca
    17941 ccagctggca ctgctgtttc atctgccgaa gtgattacta ccgaattcaa tcggcgcatt
    18001 tcttctttca ataaccctac tgcattagcc aaactgtttc ctcttaatga attggaacat
    18061 actagttcag caaaattact tgtgtgatgc gcctcagtcg atttgactgg acgcatttca
    18121 tataaacgga cagggactcc tgcttgtgcg atctgccaag cagcttcact tccggcaagc
    18181 cctgctccaa caacatttac cattttcaat gaaagaacct cttttctatt atttttggat
    18241 gtcttcttcg taatctccat ttacacagac tacttgttta ccgcctttga ctttcttctc
    18301 gaccagatat ccgtcacatt ttggacaatt tctgcccact ggtttatccc aagaagtgaa
    18361 ttcacattct gggaaacggg aacaaccata gaatagtctg tttttcttag attttcgttc
    18421 aatgacttgt ccttcatgac atactgggca agtcacaccg atttctttta cgattggttt
    18481 cgtattccga caatcaggaa aattactgca agcataaaac ttcccatatt tccctaattt
    18541 tatcaccatc ggatgtccac agacatcaca atcgaatcct gctggttcat ctttgatttg
    18601 aattttttcg attttttctt ccgcattcgt cagttctttt tcaaacggtt tatagaaacg
    18661 atcaaccact ttgacccacg cttccgtgcc ttcttcaatt ttatccaaat ctccttccat
    18721 ttctgctgtg aaatggatat cgacgatttg agggaagaat tcacagatta atgaattgac
    18781 aatttctcct agttcagtcg gctcaaatct tttttgtgtc aattttacat agtagcgtct
    18841 ttggatcgta tcaagtgttg gtgcataagt ggaaggtcgc cctaccccgt tttcttctag
    18901 tgcacgaatc aacgtagcct cactaaaacg tgctggtggt tgagtaaaat gttgttttgg
    18961 ttcaatatca acagattgga ctacatcgcc ttcttcaagt tctggaagaa tattttcttt
    19021 ctcttctttg ccgtcatctc taccttccac atacacttgc atgaatcctt tgaatttgat
    19081 ttttgaaccg ttcgcaatga agatgacacc attttgttct aatgtcactt tcattgtatc
    19141 taaaatagct ggtgtcatct gactagccac aaaacgtgac cagatcaatg tataaagttt
    19201 caattgatct ttatctaaat attgtttgag ttcatctggt gtacgaagca cactcgttgg
    19261 acgcacagct tcatgggcat cttgtgcgcc ttgagcattt ttgatctttc ggtgatcatg
    19321 tctagaaaat tcttttccat acgtatcttc aataaatgct gcggcctctg cttttgctgt
    19381 atcggcaatc cgggtagaat cagtacgcat gtatgtaatc aagccgactg ttccttgttt
    19441 acccaaagtg attccttcat ataattgctg tgctaccatc atggtttttc ttgttcgaaa
    19501 gtttaactta cgggcagctt cttgttgcag gctacttgta gtgaaaggat tcgcagggtt
    19561 tcttttgcgc tctttctttt ctactttttt aacttcgaag tctgttccat caattctagc
    19621 agtgacttct tttacacttt gtgcatctgg taatttcttt ttcttaccgt cgattcccca
    19681 gaaatttgct ttgaatttct tgcgagcttt tttaaaatta ccgtcgatgc tccaatattc
    19741 ttctggaaca aattctcgga tctctttttc acggtcaata ataattttta aagcgacaga
    19801 ttggacacgt cctgcactta accctttctt gaccttacgc cagagaatag gactgatcga
    19861 ataaccaacg attctgtcta aggtacgacg agcttgctgt gcatctacta aatctacatc
    19921 gatcgttctt ggttccttaa aagctgcttt gactgcgtct tttgtgattt cattgaagac
    19981 cacccgattt ttttctttca gatccaaccc aagtaggtac gctaaatgcc aagcaatcgc
    20041 ttctccttct ctatccgggt cacttgccaa gtaaactttt tgagcttttt ttgctgcggc
    20101 tttcaggctt ttgatgacat cgccttttcc gcgtatagaa atataatggg gttcataatt
    20161 gttttcaaaa tcgataccca ttttactttt cggtaaatct cttatatggc caacactggc
    20221 cattacttta tagtttcgtc caagatattt ctcaattgtc ttggcttttg caggtgattc
    20281 tacaatcact aaatatttat acgccattac tgaatggact cctttccatt gtcgtgttcc
    20341 tactattaaa agaggattca tacaaatcgt agctaatcat atccattcag aaaacgtttg
    20401 tcaagaaaag caaatgaaaa gtatggtgtt attctttaaa ttctgccaag atatcttcac
    20461 ccgaaaccgt gcaaactgca ccgtcttgga tcaaatgatg acatccggta gaatgttctg
    20521 ttaaaatatt tcctggaaca gaaaaaactg ttcttccaag atccaatgct tgctgtgctg
    20581 ttatcagaga gccgcttttt ttcttggctt caaagacaca tgttccttta gacaaagctg
    20641 cgataatccg atttctcatt ggaaaacaat gctttttcgg gccggattga ggaggatatt
    20701 cactcaaaag aagatgatca tttgcaatca cctcttgcaa gtcacgattt tcagcaggat
    20761 agacttgctc tatccctgtt ccaatgactg cgattgtccg tccaccatga gagattgctg
    20821 cttggtgacc gtatgtatct atccctttcg cgcagccact gacgatcaca tatccagctt
    20881 ctatcactgg ttttagtaaa taataaactg tttttttggc taaagcagaa gtgtgtcttc
    20941 caccaacaac gcttaacatg ttacaagaaa gtaaagatag atcaccatta taaaacagta
    21001 caattggcgg ataggtcaag tgaagcagct gagggggata tttgggatca aagcaagtga
    21061 taaacgactg tttcgattgg attttgcccc agttagcgtg aatttcctgc caacttttgc
    21121 gaaacagctc ccggtgtttg gttattttac ctatcttaat gatgtcttca aatccgattt
    21181 ctttataagg atactgcatc atccagttag caagtgccca ttttccttga ctactgattc
    21241 cttttgtata agcaagtttc aataaatttt cttctatttg atacatcata aaaccgcctt
    21301 tcgtctctct ttctaataag atacgtaaaa gcggctgttt tttattgtaa atattttttt
    21361 acaggtgcaa aacttttacg atggattggc gtaattcctt gtcgttcaag tccttctaag
    21421 tgttcctttg ttccataacc tgcattatgc gagaaaccat atccaggata aagcacgtca
    21481 tattctttca tcaattggtc tcgatatact ttagcaatga tacttgcagc agcaatcgac
    21541 acagatcgtg catccccttt gattattttt tcctgctgaa taggcaaatc caaggtcatc
    21601 gcatcgatca acaaatagct tggtacaatg gacaattttt ctactgcttg gatcatcgct
    21661 aatttacttg cttcataaat attcacatca tcgattgtct gctgatcaac gatcccgatc
    21721 ccgattgcca gggctttttc ttgaacttgt tgataaagaa gttctcgctt tttctctgat
    21781 aattgtttgg agtcattcag ccctaatatg atctcatttt tcggcaagat aactgcagct
    21841 gccacgacag gtccagctaa tggtcctctt cctacttcat caatgccggc aatccattgg
    21901 tgaccttgtg cgtacccttg cttttcaaag caaaacattt cttcatattt ttccttaatt
    21961 aatgcttcct ttttcaatcg tcgttcaaaa gaagccagtg cttgctgcac gcctttgcgt
    22021 ggatcatttc ttaatgattc tagtgtagga tcatctattc tctgtatgct tttcaatcgt
    22081 tctttgatac tttggatgga ttcagtcatc acttttttgc tccatttctt cgcaacgatc
    22141 cagtgtgtat cgtccaagtt ttccttgacg aatatcatgc acgactaatt cgctgccacg
    22201 atcatagtct tctttatacc cacgttttgc tgtaatatcc atcagtaatt ccggtgccaa
    22261 tttttcttct tgctcgattg ataaaccata acgatcgctg attcttcctg aataatatcg
    22321 ggcaaaaaag tctaatccgt aaatcgctaa atcatctaaa tggacaagct ggtctttgat
    22381 cgcgcctgtc agcgctagtt ttttgccgat ttcttcatct tcaaatttgg gccataaaat
    22441 ccctggtgtg tctaacaatt ccaactcatt acctaaacga agccactgct gaccttttgt
    22501 tacgccaggc ttatttcctg tctgtgcaat tttcttgcct actagtcgat tcatcaacgt
    22561 agatttccca acatttggaa tacctaagac cattgcccga atagcgcgag gcttgatccc
    22621 ccgagcagca tctcttgccc gtttttcttt caatgcttct ttagccgcag gtactagacc
    22681 tttaattcct ttactttctt gtgccgtgat agctaatgca agatggcctt gtttacgaaa
    22741 atattcttgc cacagctttg tctgttgtgg atctgccaga tccgctttat tcaataaaac
    22801 aaggcgaggt ttttgctgaa tgatctgatc tagcattgga ttacgagaag ataaaggtaa
    22861 tcgtgcgtct accaattcaa atacgatgtc cacatatttc attttttcag aaacttctcg
    22921 tcgggctttt gccatatgtc ccggaaacca ttggatggtc attgttctct ccattccttt
    22981 cataccggaa tattccccgg ctttacttgt ttttttcttt ttcaatataa attcactttt
    23041 ttattataaa gaaattccat ctattagtta agtgaaagtg aaccagtcct cattctatca
    23101 catcttcact tttttgatga tgcaaatttt tattttggtt tctatatatg aatctaaatt
    23161 tttgacagcg tttcctaaat aagagatgat agacgaacaa aacagaaagg agacgaaaca
    23221 aatgaatagt atggtttttg ttaattttcc tgttgctgat gtcaatcgtt ccgttgcttt
    23281 ttatgaaaag ctgggtttta aaaaaaatga agaattttct actgaagaag ctggttcaat
    23341 ggtatgggat gacacttttt ggataatgct tctctctcat gatttttata aaaaatttat
    23401 aaaagataaa gaaatagctg ataataaaaa aacaagtggt gctttgattt cgtttagtgt
    23461 tgaaaatgcg gatgaagtaa aaaaatttgc tcaaattgca aaagaaaatg gtggtacttt
    23521 ccacgaagta gatatgggaa tgcctgaaga agaaatgttt tcattagaag tccaagatct
    23581 agacggaaat acattagaac ccgtatggat gaagatgtaa gcagataact aatctgacgt
    23641 tttttataac aaaaaaacaa aggcggatga tacgataagt attctccgcc tctatttttt
    23701 ttattcgtac aatctctttt ttacagttta taaaagcagt cttctcaccc tttttttaat
    23761 tgttagatgc cagtgtatgt aaatcaccaa tgtgtcatga cacattggtg attttatggt
    23821 atccttttat tattaactga caaaggagag aatattttga acactttgat tgcaaaagac
    23881 gtttttagat tgcccgaaat gaatgcaaga ttgttgtcga cctctgctct tttattagcc
    23941 cttgatgtca tcttatacaa gatagcgatt ggtcctgctt attttcaaat cacattcgga
    24001 tttttaagta tggcgcttat gggttatcta tatggaccga tctgggctgg tttgcttgaa
    24061 atgttgtcga acactttaaa tttcacgata tttggttcag gaacgtttca agctgctttt
    24121 cttatcacgg ctttccttgg tggatttatt aatggcttat ttttatatca taaaaagata
    24181 aacctgcctt ccgtcatcgc tgcccaatta ttgattatga tcccagtcag cctttttatc
    24241 aattcttggc tgatgtctgt tttgtttggt gcagatttca aagtaatttt tctaggtaga
    24301 ttcatcagga atatgatcca aatccctatt caaataatgg ttgtttattc atttatcaaa
    24361 actttagagg ctagaaaagt gtttaaacga gctgtttgat tttacgtact aaggtagtaa
    24421 actgattttg gattaaacaa taaagcgtgc agtctcaaca gactgcacgc tttattgttt
    24481 ctcactggat ccattttatt tcatcaagtg gataatagac aaatcttgct ttacctagaa
    24541 tatcagtttt attgatcgtg ccaaacgaac gactatcttt tgaaactctt cgattatctc
    24601 caagtacaaa ataattatct tccggaagct tggattgtcc cgttagctct tgtagtgtaa
    24661 agtccgtcgt ataggatgca tttgcatgat ctgatttcag gtttttagtt agataaggtt
    24721 ccttaactac tttcccattg atcttcaatt gatcattttg gtagctgaca ttttctcctg
    24781 gaagaccgat tactcgtttg atataaatcg tgccatctgc taattgaaaa acaacaatat
    24841 caaatcgtct gatctccgaa aatttttcca tcacaaccat atcaccttgc ttcaacacgt
    24901 tttccattga attgccttcc actggtaccg ggatgaataa aaatccccgc aacatgaacg
    24961 caaggaatac agaaacaagt aagtatttga atacaagcca gaagcgatta atatagcgtt
    25021 gtttttttgt caatctctat caatccatcc ctcttttttt cattctttct ttattataag
    25081 aaaaatatca aaaaaatgcg actagatagc tgaaataaaa ataattcttt caattaggct
    25141 attggacaaa aaactttttt gatcataaag tacaaaacta tctcttatat gtcatgatta
    25201 ttttctaaat atttttccca tgcttcgtca aagatatcca tggacggcaa atagtcgaca
    25261 ttcagttcca gataattaga aatttcttcg tagctagagc tgtgcttagg aaattggatg
    25321 tctttaccgg cttctgtagc gaaaacagat aaagcatcat gtgtgccacc gcctcgcagt
    25381 gtcattaaat aatgaaaaaa gcttcgattc acccttcgtt cctccaattt tcttcgataa
    25441 aggcagcccg gcgtgcatgg tttcttttaa aattttcagg atgcttttta taatactctt
    25501 gatggtcttc ttctgctaga taaaatggtt gggctggttc gatttttgta acgattggct
    25561 gttcgaaacg tccactttca gctaactgtt tcttactttt ttcagcaatg atccgctgtt
    25621 cttctgtcaa ataaaagatc accgggcgat aattgtcacc gcgatcctcg aattgtccga
    25681 aagcgtcagt tggatcagtt tgctgccagt aaagttctac taattgttca tatgaaatca
    25741 atgttggatc atagataatc tccactgctt ctgtatgtcc agtcgtttgg ctttttactt
    25801 gttcataagt cggatctggt acatgccctc cagtatatcc tgacatcact gtatggatac
    25861 caggaagcgt gtcgaaaggc tggatcatac accagaagca gcctcctgca aatattgctc
    25921 gttccattat gattccccct ctaatactac tcatccgatg attttttatt ttcttttgtc
    25981 ttgctttcag tactgctggt gctagttttg ttggtatttg agttgtttga agcatcagag
    26041 gtatcttttg gcaaatatag actaaaccga atgtcatcat ttactaagtc gattttatct
    26101 gctttaatat acatcccgtt ttgcattcgg aattgatcca acctaagcat gatagtcaga
    26161 tcatctgtat tgacttcgat ccaatctggt aatttatagt ttctcttgat catattcatc
    26221 acatctttga ttggcaaact caatgttccg atagaaagac ttctagcttt tagttggaca
    26281 tttccgtttt ccatcacata cggatcaaaa tataaataga aatcgatagg aaaacctagt
    26341 acttcgaaag taccattgag tagtgcttca ttttccaaat aaaatttata ttcaatatca
    26401 ctatcttttt gatactcact aaggaaaaag ctgatgattt gattgacttt ttctttattt
    26461 gaattgatcg ttaagacagg atctccttgt ctttccgtaa gagctggtat ttctgggagt
    26521 tctggttccc gattagcaaa aatacggctg cctaaaaata cggtcgaacc aagtactacc
    26581 ccaagaagga taaggaaggc gaatttccag taatttgttt tctttgtttt gtttgaagat
    26641 acgtcagatc ttgttttcat gtttattgat catcctcctt ctctaaccat tggttttgtg
    26701 tctcgatcag ctgatctctc actgcatttg ccatcaattg ataacctaaa ttatttggat
    26761 ggaaatgatc ttcttcatag agcacattat ttttgatgcc atttagattt tctgtcgtgc
    26821 tagttgtttg atctgttcct tcttctgtga cacctacttc ctgattcaat ccttgataaa
    26881 gcaaatcatt gattgggata aagtagcagt tcggcatttt ttttgtcacc gtttctgttc
    26941 ctttgttcca attgttaaca attgtctgca tgtcagtgat ctcaggaaag ttcaaataaa
    27001 atggattgta gatgcctaaa atgtaaatag gtgcggtttt attgagggat cgaaattctt
    27061 ccaatagttc tgtgacattt tcctgatagt ttttcagtgg ctttttaaag gaattgaccg
    27121 ttaacccgaa taaattattt tggataactt tcatcaaatc attaccgcca acagtcagtg
    27181 tgataaaatc agctgttttg atattgtttc gaatttcttc ttttgttttt actcgcttta
    27241 agatctggtc acttcgttca ccatttacac catagttttc tgtttcaacc gcggtcaaat
    27301 tataacggtc ttttagatca tttgcgacaa ggggaacgaa tcctccttgc ttggtttgat
    27361 ctcctactcc ttcagtcagc gaatctccga tagctatgta gtgaagtttt tcttttttat
    27421 ttggatcttc tctcacagta gttactggtt tcattagtgg gccagctttc ggtatagaag
    27481 cagctaaacc tgcatagatg atgatcgcaa ttaataatgg gaacaaaacg aggatcaaat
    27541 gtcgtttcgt taatttcatt ttttcacctc ttgtattcga ttggttctaa tgttatcaaa
    27601 aattttatca aaaaggtagt ctttatgaaa aaagaaaaca attattttcc taattttata
    27661 aagaaaaaga gaataagctg caagcctttc aggctgaggg cttatcctct tttcgactaa
    27721 tctacataat acatgattgc aaacgcgtct ttaccagtat gcgtagcgat aaccggattc
    27781 gtatgcagta cagggatatg catgtccggg aataattctt gcaaaccctc tttgaattct
    27841 tgcgccaatt cttttgcatc cgcatgtgaa ataccgattt gtcgcacatt tggcaattct
    27901 ttcagttcat ttttcaaatt attaaaccat ttatcgaacg ttttctttcc tcgcccctta
    27961 gttacaggga ttaattcaga atgggcgaaa ttcatcacca cgcgtatgtt caaaacacta
    28021 gacagcaaac cagttgttcg gctgattctt ccacctttta ccaagttatc tagtgtggat
    28081 attccgatgt ataattttgt attgtcttgt acttttttga cttcttcaag gattttctct
    28141 actgttttac cttcttttgc taattcagct gctcgaatta cctgaaaaga taatccttgg
    28201 tcagtggtat cactgtcgat aaccgttact ttcgtttttg ttagattact ggcttgtctt
    28261 gctgcttcta ctgttccact caagcctttt gtcatatgga tcgaaatcac ttcactgccg
    28321 tcttctccta gctcatcata catcgagatg aattctccaa ttggtggttg gcttgttttg
    28381 ggcagatttt ttgctttcgc catcatttcc ataaatcttt cgccgtctag ttggtcatca
    28441 tcgggatata ctgttccgtc gatcatgatg gatagcggca tgacacgaat gcctaaagca
    28501 tcgcgtacat ttttttccat cgtacatgaa gaatctgtta cgatttttac atttgtcatt
    28561 attttctctc tctctttctt taacaagatg ccttattcat gttaaactac atgtaagaca
    28621 atttctattt ttagtataac agacaaataa tgatttttca ttaattacac ctagtaaagg
    28681 agccgttttc atggaaaaaa cgaaatttaa tcgaacgtat gaaatattaa atgaagtgtt
    28741 taatgcagtc acccatggaa ttgggactgg attgagtatc gcgggactag tggttctttt
    28801 agtaaaaggt gcccacttgc attcctccct ccatattgtc tcttatgcta tctatggatc
    28861 gatgatgatt cttttatttt taacgtctac tttgtttcat tcattgattt ttacaaaagc
    28921 aaaaaaggtg ttccaagtat tcgatcatag ttcgattttt cttttgattg caggaagtta
    28981 tactcctttt tgtttgctga gtatccgagg atggctaggt tggactttat ttgtattaat
    29041 ctggttgttt gcgattcttg gcattatata taaagcgttg acgttgcata aacgggagag
    29101 agtatcaaaa gtatctacga tcatctatat ttttatgggg tggctctgtg tcgtggctgc
    29161 tgttcctctt tatcactctc ttggaatgac tggtgttatt ttgatggtag caggcgggct
    29221 ttcttacacg ataggcgcat tcttttatag cttgaattct atccgctata tgcatgttgt
    29281 ttggcatttg tttgttatgt taggtgcagg ttttatgtac ttctctgttt tattctttac
    29341 ttaataaaaa aaataaagct atggatggga cagctctaaa taacagctag tctatccata
    29401 gcttttttat atcgtcaatt cgcctgtccc gctttttaca ggattctcat tacgctgata
    29461 cgtttcaaat tgatgcggat aacgattttt ttcatccatt tctccttgac tagtattgat
    29521 cagtgaccaa tcagaccagt caacaggtgg aaaataagca tctccatcga atacatgatg
    29581 gatgactgta cggtataata tcgtacaaaa tggcagaaat tcttgataaa cagctgaccc
    29641 tccagcgatg aaaaagatac cgtctgtttc tttttccaga gcaagcacgt cttccacact
    29701 atgcatgaca tgcacgcctt ctgctttata ggaagaatct ctcgtcaaaa caatcgtctg
    29761 acgattcggc aacggacggc tacccatccc ttcgaatgtt tttcgtccca tcactagtgt
    29821 atttgcttct gtcatttgtt tgaagaattt cagatcattt ggcaaacgcc aaggaagacg
    29881 gtcttctttt ccaatcaatc cgttttcatc ctgtgcccaa attgcagcta acattttctc
    29941 atcctttctg attctaaaca gcgataggag ctttgatcgc cggatgtggg tcatatcctt
    30001 ctaattggat atcttccatc tcaaaatcaa atactgactg cttttcctga ttcaaaacta
    30061 aagtcggaaa tgcgcgtatt tctcggctca attgttcttt catttgttcg atatgattga
    30121 tataaagatg agcatctcct aatgtgtgaa caaattcgcc aaccgctaaa cctgtttcat
    30181 gtgcaattag gtgagtcagc aacgcataac ttgcaatgtt gaacggaacg cctagaaaca
    30241 catccccact gcgttgatac aattggcagc ttagccgtcc ctcttgaaca taaaattgaa
    30301 acatcgtatg acaaggaggc aaagccatgc taggaacatc ttccggattc catgcagaaa
    30361 cgatcaatct tctagaatca ggagtctttt tgattgcttc gatcacttgt ttgatttgat
    30421 cgataaagcc accgtctttt gtttcccagt gacgccattg atagccgtag atgtgtccaa
    30481 gatcgccgta tgtttcagca aaggaatcat cggttaggat cttctcgcaa aaaagcttgc
    30541 tctgcttttt atattcttca ttgaattcag gatctgtcaa acatctatgg ccaaaatcag
    30601 tcatatctgg tccattatag tctggacttt tgatgtagcg ttcaaatgcc cattcatccc
    30661 aaatatggtt tttattttgt aatagatagc ggatattcgt atctcctttt aaaaaccaaa
    30721 gcaattcgct tttgatcaat ccaaaaggta ctcgtttcgt tgttaacaaa ggaaaccctt
    30781 tttgcagatc aaaccgcatt tggtatccga ataagcttaa tgtgcctgtg cctgttctgt
    30841 cttctttacg atgcccttct tccaacaatt ttcttcctaa gtcaagatac gcttgttcca
    30901 tcctttttcc tcctaatctt ctacccattc actcaagtat tcccaccgtg ccattttttc
    30961 ttcaagttgt gcttctgttt cagatacgtc gttttgcaat tcttgtaatc gagtgaaatt
    31021 atctccttga tgattcatct cttcttggag caatgagatt ttttcttcaa gttctgcaat
    31081 ctcatcttca atcgtttccc attctttttg ttccatgtaa gataatttct tcttttcagc
    31141 aggttccttg ctctgtattt ttggtttcgc tttttcagca ggctgctggg tctctttttg
    31201 cttcagtaaa taactggaca tgtttccgta ataaagttct tgttttccgt ttccttggaa
    31261 tactaataac ttatctgcta ccttgtccaa gaaataacgg tcatgggaaa cagtgatcac
    31321 agcacctgga aaacttctaa aataatcttc caaaatcgtc aatgttgcta tgtccaaatc
    31381 attggtcggt tcatccaata ataaaacatt aggttgctga atcagcagtt tcaacaaaaa
    31441 taaccggcgt ttttctccgc ctgaaagttt gcctatcagt gtcccatgca taaatcttgg
    31501 aaataaaaat cgttcaagta attctgctac tccgatttga ctgccatctg ctgtttttgc
    31561 ttcttcagca gcttcttgta agtaagcaat catccgttta tctggtgcca tttcttcatt
    31621 ttcttgtgta taatacgcaa gatgaaccgt ttcaccgata gacattgtac cgctatccag
    31681 gggaattctg ccagctagaa tattaagcaa tgtcgatttt cccgcaccat ttttaccagt
    31741 aatacctagt ctttcccgag attgaatcaa taaatctaaa tgttctagca gtgtttggtc
    31801 atttatacgg taactgccat ctttgatttc cagtactttt ttccctaaac gttgtgtcgc
    31861 taggttcagc tctaaatcat cttcttggtt tacttggtac aagttctcct ttagatcttc
    31921 gaaacggttg atccgtgctt gctgcttggt gccacgtgcc tgtacgccag ccctcatcca
    31981 agctaattcc tgtttataaa gccgcttgcg cttttcttct tgttctactt ctacacgatc
    32041 acgttctgct ttttctaaga cgtaagcttc ataatttcct ttatactcgt ataattttcc
    32101 aaatgaaagt tcgaagattc ggtttgctac tctatctaga aaataacgat cgtgggtaac
    32161 catcaatagt gcgccacggt attgtttcaa atagttttcc aaccactcga tcgcttcata
    32221 atctaaatgg tttgttggtt cgtctagtaa tagtaaatcg ggttcatcaa tcaacacttg
    32281 cgccagacta actcgttttt tctgaccacc tgataaagta ctgatttttt tatctaattc
    32341 actgattcct aatttttgca aaataatctt tgcgttggta tctgtagtcc aagcatcttc
    32401 tttattcatt tgttcttctg ctttagcata acgtttttgc acatcagggt cttctccgtt
    32461 ttcccctagt tcgatcaatg cttcctcata tgctcgaaca gtttggatca aggggctgtt
    32521 tccttgaaag actgcttgga gaacagttaa ttcatcggaa aattcagctg cttgagaaag
    32581 ataaccaata cggtaatcag ttggataaaa cactgtttgc cgatcaccgt cgctgctatc
    32641 gataccggca ataatattta agagacttgt tttacccgtc ccgttcgtcc caatcaaccc
    32701 gatacggtct ttttcgtgga ccaaaaaaga aatctggtca aacaaatctt tttcaccata
    32761 agtttttttg aggtcagtta cttttaattc tttcaacatg ttccctcctt atcttggata
    32821 ttgtatcata aaaatagtga acttcaggaa aatttttttg gtatttgttc tttttgtgtt
    32881 ctcaaaaaaa gaacaggacc gattcgatcc tgttctgata tgttttgttt tttataaaac
    32941 ttgaaaattt ttaccttttt attttattgg actcgttttt tttgactttg ctcgaaacgc
    33001 aaatcggaaa gaaaagttat cagatggttt gttcatcgta taagattcta acaaattgat
    33061 attcctgcga tagctgttcg cagaaaacgt cgtgattttt tcagcaactt cgtattcatc
    33121 aatgattttt ctttcaagat aataacctct tagcattttt ttcgtaaaca gactatcttg
    33181 ctggatcatc cacgaagaaa tcaaattccc cgagttcatt tttattcctt caagtttgcg
    33241 ttgctggata aaaaattgaa ccatcgtttc atcataaata tcagtcaagt tatctaaact
    33301 ttcaataatc aactgagtat ttttttgata tgtctctctg atttcttgga tatcttcatc
    33361 actaataaat gtctgacgat cagcatatct tctttgccaa aacattttcg gatggagaac
    33421 gattcgcatt aacctacgga caacaatgaa ccaaaagccg ataaaagaca aaatctggct
    33481 tgtgatagaa tgttcgaatc gagaaagaaa acgggagtaa aaacgataac cattagaaga
    33541 aagcttgccc gaacgataac tttcatccaa tccatcccgt tcgatcgaca aaatcagtgc
    33601 ttgtatttct tgtacttctt gcttttcatc atcggttaaa tcttccaagt acagatcacg
    33661 tatccgttct tgataatttt ctatcactgc ttcagtggct aaaaattctt ttgtattacg
    33721 atcaatttcc tttatttctt ttcgcaaaac ttcaacgacc tcttctaaaa tcatcaaagc
    33781 attcaaatcc gtgcttttcg cttcctctgt ttccgtcagc ataggcaaga caatgatccc
    33841 tatgaccaaa gtcactaaga tgacacccgc cgtcagaaac aaaagcaaag accgctggta
    33901 aaacatcata ttattgattg aaaatggcaa aataaaaatc gtagccaaac tgactgttcc
    33961 ctttacaccg ccaaatgtta agatcaagat ctcgttcaac tgttttttga actttttact
    34021 gccatctttg aatacataaa aaagactgat agaaatgaat ctgatcacaa aaagcatgac
    34081 agagattaat acgataatcg ctaataaaag accgtttgga tataaaccgt ctccccatac
    34141 tggcgagaac acttgcgtca attcgattcc taaaaatata aatactaatg cattcagtgt
    34201 aaaagcaata gttgtccatg tactgtggga caagctcgac aattctgcat caaacacaga
    34261 gattttccta aaaccagaag cttggagaat acctgctgcc actgcagcaa tgattccaga
    34321 tacatcaaat gcctctgcca atacataggc tagaaaagga agcaaaagtt cgatcagcag
    34381 ataccctgtg acatcttgtg ctgatgcttt ttcgatcaaa tgaattattt tttgtttgaa
    34441 ccagacaagc aaaaagccga tcaaagctcc cccaatacta gaaactacta gactcatccc
    34501 cgcgtttact gctgaaaaag atccggtgat cagcgcacca agagcaaact ggaaggcagt
    34561 aacaccagat gcatcattca aaagaccttc tccttccaaa atatgcatcg cctttttagg
    34621 gatattcact cgtccagaaa gagaactgac tgctaccgca tctgtcggac ctaacgctgc
    34681 tccaaaagca aagcaggcag caagtgggac acttggcaac aggaatgata acgtcgcacc
    34741 taccccgaca agggtcaaaa tgactcctcc aaatgccaag aacaaaattg tcccgaaatt
    34801 tttgagaatc gaagaaatat ctgctttttc tccttctcta aataacaatg gtgcaataat
    34861 cataactaag aacaattcag gttcaaaatc gattgattgt ccccactctg tcagacctaa
    34921 taccactcca aggaaaattt ggatcagtgg agctggaatc attggcaaaa tgcggctagc
    34981 tatgttcgat aaggtgatcg ttactgcaaa tacaataact aactcagcaa attccatcgt
    35041 ccatcccctt tattttttat tttgtgtaag catttttaaa aattgttctt ttttctttaa
    35101 aattttggtt tcgactactt caacctgtgt ttggttcccc tctaattcac actgtacacg
    35161 ttttgactcc aaacgaagca gatcatgttt cagacgttcc aactgacgat acatcaatat
    35221 atttctttta cgcaacttac aaagtatttg acggcggtca tccatcgaaa gggcgccata
    35281 gcgatcatgc aacagttttt tttgttgttc aaaactctct ctcattttcc agatctccta
    35341 tacacaaact tccatcatta tagcaaagtt ctttttggat gaaaaatatt tcattgtttc
    35401 atcgtttatt gctagttaga aatttccata aatttttcaa cgcctcattc tattccaaat
    35461 agtatcagat atcaagtaaa acttaagaaa gataaaagtt tctgacaaaa ggatgtttac
    35521 tttcccattc ctgcctttct tgttctttta tcacaacaaa aaaatggggc tgcgacaaaa
    35581 atcttgtcac agtcccttat tctgaataaa cggtgtggaa gagacagcct atcagtagta
    35641 ataagacaca tctctttcac agcctcattt ttgcgtaaaa atcgatttat tcgaaaaatt
    35701 ccccgtatac atcttctaca cgttgatctg gattgatcac gatatacaag ttacctgttt
    35761 tttcgctgat ttttgttgat tgatattgat tgtctaatcc ttctgttcct ttatctagat
    35821 atgggaagta cacaagatca ggtgtgccat ttcggtaaag gatttccatt cgctcgatat
    35881 cttcgtattt caatgcgcga ttaaacatgc ccatttccag tccgcctagg ttgatatcat
    35941 gtgtcgcaac tgcgtcccct tcatggaaga tttcgatttt aaatccagca cacggatgga
    36001 tttcaacaaa ttcactgcca ttgattcgtc caaaacttgt tgtgatttgt ttgatccaaa
    36061 gatcgccgat atgacggcgg ttgatcgtcc aggtttctcc atttctaaaa taaaatttta
    36121 gcgctgtcat ttctttactc attaaaaaga ctcctttatg atgtaattta ttcttgtact
    36181 acctcagttt agcacaaatt tatgtaagtg gtcacatctt atgttttttc ttctaatgac
    36241 gtatctgccc actttaagta gccaacaaag ctgagcagat acagtctagt gttttttaaa
    36301 tcaatttttc tttcgataaa aaatccaaaa cctgtttttt atcatttttt attctttgtt
    36361 ctacgacggc tttttcagct aattgcaaag cttcactaac ccacttacca ggtttttttc
    36421 cagtttcttc tagcaagatt ttaccatcta ctgctaattc gcttaatgac ttgataggta
    36481 aacgatcata ggattctcct acggcatcca tctgaggtgt ttcgtcaaaa tagatcatca
    36541 attcttctac ttgcagtgca tgttttttgc ctaagaagta caattcgaat ggttccaaag
    36601 ctccagtttc tcgttgtcgt agtccttgga caagtgcttg aacgtcttta atcatttggt
    36661 tagaacactt ccacgatttc aaaaaggaac gaatctcatt ttcttttaga tccagttggc
    36721 tgatcaataa tgcccatgct tggctctctt ctttcaatgg gacggatggt aattcagcaa
    36781 aacgtaaaag tgcttcgcct tcttctttca aaccgggaca gcaaatgtag cactctgttt
    36841 caataaatgc atggattccc gcggcccgtt catttcccaa gagcatcttg atgaattcca
    36901 catttatacg ttctacagat attttaccta atagctcgtg gttttctttg atggcgtaga
    36961 aggtttcttc ctctaatttg aaccctagtt gactgacaaa acgcaacccg cgcatcattc
    37021 gtaaggcatc ttcatggaac cgctcatgag gattgcctac agctcgcaag atctgttctt
    37081 ctagatcttg cagaccatcg aacaaatcga tgatttctcc atcttctttc aaagcaaacg
    37141 cattgatcgt aaaatctctt cttttcaaat cttctgccaa cgaacgaacg aattcgacat
    37201 gatctggtct acggtagtcc tgataagttg attccgtccg aaatgtggtg atctcatatt
    37261 gttcatcatt ttctaatacc aacacagttc catgttcgat cccaatatct atcgtttttg
    37321 gaaaaagctg tttgatttct tctggaaatg cgcttgttgc gatatccaca tcatggattg
    37381 gctggttcag caagatatca cgaacacttc cacctacaaa ataagcttca tatcctgcat
    37441 tctctaattt tttcagaact ggaattgcct tttggtattc cagaggtaat tgttttaatt
    37501 tcatttttcc aacctttcct gcgtgtttct tgtcctgaga taaagactca gttgcatggt
    37561 gactgtttga caagtccgtt tcagagtctt caaggccagg accacttcat cttgtttact
    37621 cgtccttacg ctcaaagcga ttatggtctc tttgattgaa tttttccatg tttttttcaa
    37681 aaacttcagt taagtcgata ttcaatgaat tagccatgat catcgtaacg aataaaacat
    37741 caccaagttc ttctgctacc gagttaactg gttcagaagc ctttttgctt ttttctccat
    37801 aagtgtggtt gacttctctt gccaattcac ctacttcttc agttaatcga gccatctgag
    37861 ctaatggaga gaaatacccc accttgaatt gctggatata ttcatccact tcctgctgca
    37921 tactgtataa agaacgcttt ttatccatct ttttccctcc aaaactatct taccaaaact
    37981 ttaacgcaaa tcctagataa gagcaattga gaaaatcgaa tttccatgct acatttagga
    38041 aggaatttct aaatggaaat tctgtgaaaa tacataattg aaagctggaa ttcatatggt
    38101 caaacgaaaa acagtaaaag aagttctttt tatcattata ggaacaagta tttatgcatt
    38161 tggtcttgtt tacttgaaca tcgctaatca tttagcagaa gggggagtct cagggatcac
    38221 cttgatctta agagctttat ttggtattga tccagcttat acgactttat taatcaacat
    38281 cccattgatt ttactaggag gaaagatcct cggtaaacgt tccttggcct atactgttct
    38341 aggtacactt tctttgtcat tctttttatg gatctggcaa agggttccac tagaaatcaa
    38401 tttacagcat gatctactga tcgtttctct acttgcgggt ttagttgcag gtgtaggaag
    38461 cgggatcgtc taccgcatgg gtggaacaac aggcggcagt gatattatcg ctcggatttt
    38521 agaacaaaat tacggcatca ctatggggcg ttccctattg gcatttgata tcatcgtctt
    38581 acttgcttca ttaacctata tcgacttgaa acgtatgatg tatacgttga ttgtttcgta
    38641 tgttttcagt cgtgtgattg attcgatctt agatggcgga tattctgcaa aaggtctact
    38701 tgtcgtctcc aacaaaagcg aagagattgc accactactg atgaccggtc tgcaaagagg
    38761 tgtgactttc ctttctggag aaggcgcatt ctctggtaat tcaaaaaaaa tcatctatat
    38821 ggtcgttagc tctagtgaat taactgaagc taagaggatc gtccacgaga ttgacgaaaa
    38881 agctttcctt tcaatcatca atgtgcatga agtggaaggg caaggcttta cttatttgaa
    38941 gccacagaca agattactga aaaaactata agaaaaaaga caaagatagg ctatgaggaa
    39001 agattccaca tccagctgac ctttgtcttt tttagtacta tactattttt aactaattgt
    39061 tatgttcact tacccggtta cttttctttt gtgtctgcaa aaggatcttt cggttaactt
    39121 catcagataa tttcaaaaaa gcatccctat ctccatcttc tagtgcttga tcgatttgag
    39181 cataaagcat ttttagtttt gcctcttctt ctttttcttg aaaatatcgt tcaattaatt
    39241 cagtatcttc ttcactgact gaagaatccc aagaagaaaa tggattgtct tctaagatag
    39301 atagatattc tcttgtctgc caagcatttt cgaatataca ttccacatat aaaggctttt
    39361 tccaattcaa acggatttca tgaaaaatct ggtctgtgtc cgtaaattct tttccctgca
    39421 aaaacaattt catgggttcc ccttcaacag atagatcact gatctgcagt cctcgatccg
    39481 caaaattcgc cccttcaaca aagtggacat tgcttaaaat cgcttcatga ttggcaagat
    39541 aattcaagat ccaaaaaact tctcttcggc taaaagatac atgattgacc atccacgtta
    39601 aaaaattctt cttttcccgt acatcaatta gcatttttct cacctctctg ttaggtcatc
    39661 taataatgac agtgcctcca tatctcctgg ttcaagtgtt aaataataag tcaataattc
    39721 ttgcgctctt ttcagctgcc cttcttctct taagaaaaag gcatactctt tcaagaaatc
    39781 tggttcatgt gatagttcat gataagcctg ttcatagtgt acagctgcaa cggtaaagtc
    39841 ttctaattca ttataagcat gggctaggtt ccattctgca taaggattag cagtttcttc
    39901 catctgattg atcacttgta tcacatcttc atatctttca tcatccaagt aaagattact
    39961 taaagtaagt aatgtttcat cttgtttgtc tcctacttct aaagctttca gtaaaagttc
    40021 ttctgctcgc tgtctatcat gcagacggaa agcattttcc gaggccaggt gataaagttc
    40081 gacttggtaa ggattttctt tgattccttc ttctaacact gtttgtgctt cttcaatcat
    40141 ttcttcttct tgaagagctt gtcctagata tagatataac gattgataat gcggattaac
    40201 ttctcgaagt tcttccagat agttgattgc ctgctgattt tctttcaatt gaagattcgt
    40261 aaaagctagc tggaacagtc gatcatctgt cctttcttct ttcagtgctt cttctaaagg
    40321 tacgatagct gcttcgaatt ctccttgcat acttaaggat tgtcctaaac gttcctgcat
    40381 cgagattcct gaaatttcat ttatcccgct tgccaacaat gtttcataaa ccactgctgc
    40441 ctctttgaaa cgatcaactg aaaaatacaa ttcagctagc gcaaactgga tcaatggttc
    40501 atcaggaagc aacccagctg cttctttcaa ttttgcttca ctcacttcag ggattccgat
    40561 aacttggtac aaatcagcta tcgccaataa gctttgcgga tagtaatcac tttgcttatc
    40621 cactttttcc aggtattcaa aagctaagtc gatctcatta tcttcgattg caatttctgc
    40681 taacgggatg ttcagtccgt cattttctgg gtattggttg atcagttgtt caaaaatctg
    40741 ttttgcttcg atcaaaaagc caatagccag caattcttcg cctagttcag ctaatatatc
    40801 tgctgggtct tcttttaatg ctttttctaa aaagatttgt gcttgtgaca agtcttcatc
    40861 tgataaagct tgcaacattt tttcgctatt tgtattcatt tcaattccct cttatctcac
    40921 tgacgatttg ttgaaatacc gtcattgttc tcaataattc tttttcgttt ggatgttggt
    40981 atccgtctat tatacctatt ttttctaaaa caagtatttt tttgcttttt tctgccaaaa
    41041 aaagaacttt ttccaaatac tccatctttg aaatctgttc cagccagtgg attggatagc
    41101 caagcaagtc cagccacaca aaaaagtttt ttagttggaa atcaaaagga tatgcttgga
    41161 gattccacac gaaatgaaac atcattccta aaaatttttt catactagca gaaagtagat
    41221 ggccattttc ggtcagataa aaagcttgtt caaacagttt accataattt gacaggtttt
    41281 ctgcctctaa ttgataaaaa tagatcattt cttcgatcat cccggcaaac ggccgagtcg
    41341 ttaattgctt tttatttgga tagtttttat acagattttg caaaaaacga tgatcacaaa
    41401 tcattccgca acagataaaa gtcaaaaagt caatctgctt tccgtccacc tgccgctcgc
    41461 tgattgtttg atcataaacg atgcgttctg gcagattgat ggtttgcagc actacacgat
    41521 ttggtagctg caaaatcgtc cgctgcggtg ttaatgctcg gcttagagaa cggatcgata
    41581 cagggatcat ccatagtgat gaatcaaggg ttgtatgttt ttgaaaaaaa cctgccagat
    41641 ccatgatccc ttcatttcca aatccgatga taaacatgga ttgattttcg ggatagcgtt
    41701 tgacgaaatc aagcaggttc tttaattctg ttaaatgatt gcattgagtg ttggcacaaa
    41761 tataccagtc attgtttgct tgatttgcaa ataacgggtt gatcttatct gcaaacaaat
    41821 cataatagcg ctgattcgtt aaaaataaga ttggctgatc aatggaaagt tctcttagct
    41881 gactgactag cgtttctccg taaaacactt tcgtcaacgc atcttctact tgataatcaa
    41941 gttccatacg catccctcct cttcttattt ttattttacc attagtaagc aaattctaga
    42001 aaagataaga gcaaagctca cctcataact tgcaaataaa taaaaattaa ataaaataca
    42061 tgtgttttct atgtatgaca tacggattcg gaatctctgt ctcttattta ttccttttct
    42121 gctaggaaat aaaaagaaaa gcacttgtag ccctagagcc acaagcgctt tttcaactgt
    42181 cttatttaac agcgtctttt aatgctttac ctggtttgaa tgcaggtact ttgctagctg
    42241 gaatttcgat ttcttcacca gtttgtgggt tacgaccttt gcgagctgcg cgttcgcgaa
    42301 cttcaaagtt accaaaaccg attaattgaa ctttttcgcc gttagctaaa gcatcttgaa
    42361 tagttgaaaa tacagcatct actgctgcag ttgcatcttt tttagttaaa tcagtagctg
    42421 aagcaacttt ttcgattaat tctgctttgt ttgccatgga tagattcacc tcctccacaa
    42481 gagatatgat agaaatatca tttagttaaa actttctgag tggtccagaa gtttaaaaag
    42541 aaatattgat taacttcaat attctgttat cacgatatca tatgaaccgc ttaatagcaa
    42601 ggtttttacc aattttcaca tgcttttttt agtcatagaa acgtaacaaa cgaaactgtc
    42661 tttttctttt gaaaaaaaaa cgtcgatatg gtaaaatgcc tattttctcc tacgagggat
    42721 aattcggatg gacgtccctt caaaagtaaa tgcttttctg atttgatttt ctaagaaacg
    42781 ttcataagaa aaatgcatca attcctcttc attgacaaaa acgacaaatg taggtggttt
    42841 gacagcgact tgtgtagcat aaaaaatctt caggcgtttt cctttatctg ttggtgttgg
    42901 attgattgct acagcatcca taatgatatc attcaacaca gccgaagaga tacgaagatt
    42961 ctggttcata cttacttgtt cgatcatttc aggcagacgt tccaaccgtt gtttagtcac
    43021 tgcagaaaca aaaacgattg gagcgtaatc aagataccgg aattcatcac gaatctcttg
    43081 ttcgaaatca cgcattgtat tggtttcttt ctttacaaga tcccatttat tcacgacgat
    43141 aataattcca cgaccagctt catgggcgta acccgctact cgcttgtctt gttcccgaat
    43201 cccttcttca gcattcagta ccatcaaaac gatatcagaa cggtcaatgg cacgcattgc
    43261 acgcatcacg ctgtattttt cagtattttc gtatactttt ccgcgtttac gcataccagc
    43321 tgtatctatc attaagaatt tctgaccact ttcagaaacg aagtgggtgt cgattgcgtc
    43381 tcgggtcgtt ccttcaatat ccgaaacaat tacacgttct tctcctaaaa tcgcattgat
    43441 caaagaggat ttaccaacat ttgggcgacc aatcaaacta aacttaatcg tgtcgtcgtc
    43501 ctcttcttca gtctcttcag agaaatactt cactgcttca tctaaaatat caccaatccc
    43561 tagtccatgg cttcctgaaa caggataagg atcgcctagc cctaaggaat aaaattcata
    43621 gatatcgttt ctcatttctg gattatctac tttattgact gctaaaatca ctggtttatt
    43681 acttctgtat aaaattttcg caaccatctc atctgcgtct gtcacgcctt cgcgtccgct
    43741 gactacacaa atgattacat ctgcttcttc aatcgcgatt tctgcttgat gcttgatctg
    43801 atccataaaa ggttcatcgc caagatcaat tccgcctgtg tcgatcacgc tgaattctcg
    43861 acctaaccat tcaccttttg cataaatacg atcacgagtt actccaggag tatcttcgac
    43921 aatcgagata cgctcaccag cgatgcggtt aaaaatcgta gacttaccga cgttcgggcg
    43981 gccaacgatt gcaattgttg gatttgccat attatttcct cctcacaagt ttccaatctc
    44041 acttagttta acgaatgcat tgccaacttt caagcataga ttgtcaatta aacgaagtat
    44101 ttttattcct tattgaaata ctaatcgctt ttcaaaagaa aaactgagac aaaagcagct
    44161 gctttcatct cagtcacaga tacaaaatca attatttttc agaatcatcg gttgcttttt
    44221 cttctacttc ttctttcaac gcatcaccta aaatgtctcc catagtaaat ccagtatttt
    44281 cttctggtaa ttcataagac tcaacatttt ttggttcttc ttctgaagct ggtttttctt
    44341 ctaaagcttt gatactcaat gcaatacgat gttcttctgg atggatctct aatactttca
    44401 ctttcacttc gtcaccttca tgaagcactt catgtggtgt cgcaatatgt ttatgtgaaa
    44461 tttgagagat atggactagc ccttctactc cagggaacac ttcaacaaag gcaccgaagc
    44521 ttgtcaaacg tttaactgtt ccgtctaata ctgtgccaac tggagctttt gtatcgattt
    44581 ctgaccaagg tccaggctgt gtgtctttga ttgacaagga aacacgttct tgttcaggat
    44641 tgatagacaa cactttgaca tttacatcat cattgacagc caatacatca cttggttttg
    44701 ctacatgact atgtgaaatc tctgagacat ggactagacc gtcaattccg cctaggtcga
    44761 caaatgcgcc aaaatcagta agacgtgcaa cacgtccact gagaacatct ccctcatgga
    44821 tagttgaaag aatttctttt ttcttttctt ctctttcgtt ttccactacc gctttatgcg
    44881 ataagatcaa acgattttct gatggttcga tttcgatgat tttaaagctc aatgttttgc
    44941 ctttatagtc tgaaaagtct gcaacaaaat gatcttccac cattgatgca gggacaaaac
    45001 cacgtacacc gacgtcaacg actaaaccgc ctttgacaac atttgtaaca ggtgcttcga
    45061 tgaccttgcc ctcttggaaa tctctttcga tatcttccca aactttttta gcatctaaac
    45121 ggcgttttga aagtagatag ctgccgtttt ctttatcttt gccgatcgta ctgataacga
    45181 ctaaatctaa tacatcaccg acttttacta cttcgctgat atcttctacc ggcaaagttg
    45241 ataattcttt tgccggaacg actccttcaa ctccagcccc ttcgattccg acaatcactt
    45301 gtttgtcttc aatgactaaa acttcgccct taacaacatc gccaactttt acttcttgta
    45361 cgcttttcat tgcgtcttcc attgactggt tgttctcttg attttgatca aattctgtca
    45421 taacacttgt cctcctaacc aacattctgc cgtaagtacg gtactgtttt tagtttaatt
    45481 gattattcaa aaaaaataaa gcgatttcgt tcgttttcct tgaaaaaaca attgtttttc
    45541 attttttttc ttaatttaaa aaagaagata accttttttc aaaacaacag cttttattgc
    45601 tgcaacgact tctggaatcg atttgccagt cgtatcgata cgaacagcat cctctgcttg
    45661 cttcagcgga gagacgtccc ttgttgaatc ataatggtct ctttcctgta tctctttcgt
    45721 cagtgtttca agatcagtcg gaattccttt ttcttggttc tctttgaaac gtctttctgc
    45781 acgctcactt acgcttgcta ctaaaaagat tttcacttct gcattcggta atacagctgt
    45841 cccgatgtct cttccgtcca tgacaacgcc accgcgttcc cctatttttc gttggacagc
    45901 aactaattct tctctgactt ttccatgtgc agagacttca gaaacagctt ttgtgacatc
    45961 tggttgacgg atttctaaag tcacatcttt tgatgctatg aatacatgct gtccatcttc
    46021 ttgttgcgaa aaagagatag gatacttttt gatcagcgaa actagccctt cttcatctga
    46081 aaaagataca ttgttcgtaa tagctaaata agttactgcg cgatacatgg caccggtatc
    46141 tgtataaata taattcaatt cttttgctaa tatcttggca acggtacttt tcccagatga
    46201 agcaggcccg tcgattgcaa tactgatttg tgtcatgata taactccttt ttctcagaaa
    46261 aaaagccgca aagcgcggct attattattt aattcttaat tcttgaccag ggtaaagcat
    46321 aaagttgttt ggatctaagc cattcaattc aaacaattga tcagtggtga tccctgcacg
    46381 ctcagccact tgttttggac cttcgcctgc ttgaacagtc gttgttgaac cggctgcagc
    46441 tgatgaagaa ggtgttgttt ctgctgcatt gctgcttgaa tcccctgctt gataagttgc
    46501 ctcacttgag gaagtcggtg ttgtctctgc tgcaatactg ctttctgacg ttacacctgt
    46561 atcttgagac acagtagatt cttccgcgat tgtactagat tctactgttg aagtctcagt
    46621 tgactcctct tttgttgtac ttgtagaact ttctactact gatgtcgaag tttcagaaga
    46681 agttgctgct gttgcattgt tgcttgatcc atttctgatc cagaaataag cacctgctgg
    46741 aatagcgata cataagacca gtaaaatcaa aaatagcgaa agaaataatg tatttccttt
    46801 cttttgttgt ctctgagaac ttcttgatga aacttcatca tctgtatcgt agattggttg
    46861 ttcccatggt tcttgtgttt cgttattttc tgtagattga tgtctatctt ttctgctcac
    46921 tgttttacct cctaaactct atcgtgtgta ttataccata ggaaaaagtg tcttgtccta
    46981 aaaaatcaat gttccatgtt ttttttaaat aaatttagta aaatcgttcc ccaatgaagt
    47041 tgttcagtct tagaaaaaag cttcctcttt ggcagaagtt ctgcttttgc tccatcaata
    47101 tcacaacaat tctgcggctt ttcggagagt ttttcgccaa aataagctaa gatgaatttt
    47161 ctgcggcagt tttcttcatt aatatagcga agcatctgct gcaggcggaa ttctttttct
    47221 ttttcctgac gtttgagccg ttccacccaa ttttctggtt tttcagactg ctggatcagc
    47281 tccatccatt ttttttgcag ctcatcaaag ggagcttgct ctgtggcata ttccaaataa
    47341 agctcaaaac tttgtcgctg ttctctagaa agttgattaa agaaataatg gatacgttca
    47401 tccccacttt gataaaaaag aattgctgca ctttcttcct gatctctgcc tgctcgaccg
    47461 atttcttgta catagttttc tagactgtct ggcaaatcat aatggaccac ataacggata
    47521 tcagatttat cgatccccat accaaatgca ttcgtagcaa tgagaaactg cagctgattt
    47581 tttacaaact gctgttgaag ttgtcttctt tgagctgcat caagaccacc gtgatagtat
    47641 ccaactgtaa aacgttccct gaataaatga tacaatcgtt cgacttcttt ttttgttgca
    47701 caataaatga ttgccgctcc ttgtgctctt tccatgaagt gttcaagttc ttgttctttt
    47761 tgctgcgttt tccgaacaaa aagcgagata ttttgccgat tgactgattg tctgatctct
    47821 tttggtggtc gatcaaatag tacatgacgt atatctcttg ctactaaatc tgttgctgtc
    47881 gccgttagtg ccagtgtgac cgggtttcct aaaagctttc ggatttttcc taactgttga
    47941 tattctggac ggaaatcaac tccccattga gacacgcaat gagcctcatc tactacatat
    48001 aacgcaatat tttgtttttt cagatgctct aaaagagaag gattagtcaa catttcggga
    48061 ctcaaaaaca aaaatttata ttgcgataga tgacggagga cgtatcttct ttcagattgc
    48121 gaaagtaaac tattgaaagc agctactcgt ttctcccctc gtttttgtaa ttgcgtcact
    48181 tgatcttcca ttagagaaag cagcggtgac acgatgatga ccagaccttc cattaaatac
    48241 cccgtcaatt gatagcaaag gctttttccc gttcctgtag gcaaaatagc gagagtatct
    48301 tctccatcaa gcaacgcctg aataatttct tcttggccgg gacgaaatga atcaaatcca
    48361 aaatattttt ttaattcatt tattaacatt ctgtatcgct tcctttctca atagatagat
    48421 ttgatacaaa cgaaattctc cataatctaa ttgtccatct acattccatt cgctaaagcg
    48481 ccactctcgc acggaatcct tatttggttc caaacgttcg attgtttctg cagagagaat
    48541 ccactcgtat ggaaaatcat caaaaaacaa ggcccactca ataagatgat ctgttactgt
    48601 tcctcttttt aaatgacgga ttgccatgat ctggtcaatt gtctgaccat tcataaacat
    48661 ctgcttggtg atcatcatgc tttgattgaa attttgctgt aataatgaat cgatcaaagc
    48721 gtgccaaagc gaatctggcc gtttttcgat ttgtgctaac aaaaggtgga tacatctgct
    48781 ttgttgcaga taaaccgctg actcatcatt gttttttgcc agctgataag gaagcagccc
    48841 tgttcgctca tttccagata attggttagc taaaaaatct gctgcttctt ctggtatctc
    48901 cgaaaacagc tgcaccaaac tctcatacgc agtatcaatc aaaatttcac gtggcaattg
    48961 gctttcacta agccattttt ttagttggaa agtataaaaa ggacttgtct ctgctggaag
    49021 atagtcttga atacccgttg ccagattaga aattacttga acagcaaatt taatgagccg
    49081 ccaactagtt tcccctgttc tgccatagcg gtcaaaacgc aaaccagtat gttctatttg
    49141 atgttcggac aacatatcag cccctgcagg cgttagcttt gcttcatttt catttatttc
    49201 gatccaacct tgctgcgcaa ttttttgcaa aatttgataa aacttatcct gcttcaattc
    49261 tggaaaactg ttatggataa acaaaagttc gtgggtaaat ccataaataa gtactgaagt
    49321 cgttcgtttt cccacaagga gttggtaaag agaactaatc cgcagcttgt gtcctgatga
    49381 aaatagcgat aaaataaaaa caatcatatt attctcctta agttaggatg gttagaaatg
    49441 tcactactat gtaaacttgt acctgaacgc tgtattgcat gcggtctttg tcaaatcgaa
    49501 gcgccagata ttttcgatta tgatgaagaa ggaatcgttt tatttgccca agaaccagag
    49561 gctcatcaac agttcgtgat gccggaagaa gaaacatatg taaaaaaagc gtatcaaaaa
    49621 tgtccagttc gagcgatttt attagaaaat aaaatataaa tataaacgaa actttaaaaa
    49681 cgtacactaa gttctctaaa cttgaaaata agccgggatc tgtttctctt gttccgtgaa
    49741 atcccgactt attttgaaag attcatttgc tatctatagt taattgacta gttttttcac
    49801 ggaccctata ggacccattt atattatttc aactttttca gccagttttc caatgtattg
    49861 acgatcacag tttgctggtc tgcgttagaa atttctgcct ctccatctcc tttttgctca
    49921 ccatagctgc caaaacctcc atgatttccg ccattgattg atacatactc tgttctttcc
    49981 ggtaaatact gcttagcttc ttgataagct tcctgattca atactttatc ttttgtcgcc
    50041 gtgatcgata aaacaggaac agctgattct gtcaatgttc cttttttgtc gggataactt
    50101 gccatgaaga ataccccttt taaatgtttg tctgaatgat tcttattgac ataacgactt
    50161 gccattacgc cacctaatga atggccaccg atcacataat cggaatttgg aaaatcttct
    50221 ttgaccttat ccgctttgtt tccgcccatc actgctagat caagtggcat tttgacaata
    50281 gcgactgaaa agccgttttt tgctaaatct tgcgcccaaa tactataact ttctggctct
    50341 acgagagcac caggataaaa aataagtaat ggagactttc catgattctt tttctctcct
    50401 tcaaaaaata agtaatcttc tttgtttttt ccttctttta ccaacacttg cgcttctgac
    50461 gatggttcgt acgtattttg ctgtatatag taataaccgg ctccaccgag taatcctaaa
    50521 atgatgacta agccaattag tattcgtcta aatattttca ctttctccca ccttttctat
    50581 ctgagtgacc cctttttctt aatcaagtat gattatacct taaaaaaata agagagaaat
    50641 gcaaactttc cagcatcaaa taaaaaaaga cggaatatcc atttgaatat ccgccctttt
    50701 tgtatgttta tttttattta gcacataaac gatacacagc ttctgcataa atttccattg
    50761 ctttatacat actacttaat tcccatcgtt cattcgcctg gtgcataaag tcaggagtat
    50821 cagggaacat cgcaccgaat gccacacact ggttcatcgt acgagcaaaa gtagcgccgc
    50881 ctgatacaaa cggttcagtc atgtctccag taatatcgcg atatgtcccc aatagatttt
    50941 tcactaactc actgtctagt ggcacgtata atgaatcaag gaagtcaaat tcttcataag
    51001 tcaacccata tttttctgct gttttagtta atttagctac taaatcatct ttcttgaatg
    51061 taacagggat tctcatatct acaccgattt ttgtttgttc tggtgtgatt tccaaacttg
    51121 caaagttcat cgttagctcg ccggattgtt catcttctgt tttgcccacg acagcttcac
    51181 cagttgcatt ttcttgaact aattttccta agaaattgat tgggccaaaa tcaaatactt
    51241 ctgaaagagc aattgccaga cgagaaatag cattcactcc ttgtgctgca tctttcgcgt
    51301 ggatactttt accaagaacg acgatgcctt caccttgttc ttcgaaatcg aattcgtgtt
    51361 ttttcaatgc ttcttttact tcagaaagct tttctccaga gtaaggagct gcatcaggaa
    51421 caacattcaa cgctcctcca gcttttacag aaaactcgtt cgttcctggt cctgtcaagt
    51481 aagcttgcaa taagcctttt tctgcataaa ttaaaggaaa ttcagcatct ggcgcaaatc
    51541 cttgcgtaat tccttcttct ttttcgttat atttttctaa acaacgccat aaattttctt
    51601 catctgtacc aaagataaaa cgaatacgtg tcttgaattc cacgccagca tcaatcaaag
    51661 ctttgacggc atacattgcc gcaatagaag gacctttgtc atcttgggat ccgcgaccaa
    51721 ctaaccagcc gtcttttata gttggatcga atggttttgt ttcccaatta ttttcgtccc
    51781 ctgctggaac aacgtccata tgacacaaga taccgaataa ttcatctcca gagccaatct
    51841 ctgaataacc gtaatagcct tctggatctt taaatgttct aaatcctagc ttttcactga
    51901 tttccaatac tttatccaaa gcttcaatca cttttttacc gaagggatgt ccttgtcctg
    51961 aatctgcttc atctagtacg gaaggaattc ggatcaattc gctcaatgat tctaatgctt
    52021 gttcatgatg ttgttctgtc acaaattttt tcatgatatt atcctcctaa tatgttaaaa
    52081 agggtcatgt caaattcctc cgacacaacc tcttcttctc aaataatgac gttttaagcc
    52141 tgctccatca gcaagcagaa tgttcttaac aaatgatgaa agaaaaaaca ctcactgaat
    52201 ggagctattg acttatccac gtgcttatcg atagccgttt atcggtttct tcattcttat
    52261 gatagacctt gtacctgtat ttgtctaggt ttagaacatt gctgctacac ctaggatcac
    52321 acagatggct acaaataata tcgcaattaa tttaccggta aatttccacc acactgaaac
    52381 atcgaaacga gcaattgcta cagcacccat tacgatagca gatgttggtg taattaagtt
    52441 tactaaacca gatgcagatt gataagcagt gattactaaa tccttaccga cgccggcaaa
    52501 ttcacccata ggtcccatga ttcccattgt tgcagcagct aagccggaag ttgaaggaat
    52561 caagaatgac atagggatat agaaaataaa tgtaataatg atgaatacac ttgaagataa
    52621 tgaacttaat ccttgttcgc cccaatgtaa gatggtgtct gtgattaatc cattgttcat
    52681 aaccacttgg ataccacgag caacagctac tacgattgct acaccgatca aatcagaagc
    52741 accagctaaa aattcagaga caaattcaga ctctttcatg ccataagtga ttgctactac
    52801 gatggacatt actaagaata acatagtaat ttctgggaag taccagtcac ctaatggaag
    52861 catgctttta cctagaaccg tacctagtac cggaaggttt gttaaccagt ttgtcaatga
    52921 ttcaaaaatc gtgaaattcg cattcaaggt tgtccaagga atcaaactga tgatcatgat
    52981 accaaaagta ataaagaaca atacattaac atgtttttgt tttttcgtga ttacttcttg
    53041 acgaccgatt gcttcaatat cgaaatgctt catatcttct ttacgttggt tgtatactaa
    53101 tgattttgtt ggatcttttt cgatctttga tgcataacga tacacatata caatagaaat
    53161 agctaacaaa ataacgaaca tcaagaatcg aagaccaata ccttcaccca tcgaaatccc
    53221 aacagcttgt gaagctacgc ctgttgcaaa aggatttacc gttgaagcta gacagcctac
    53281 ttgagaccct actaatacga ttgctacagc tactactgta tcaaagccta cagccatcat
    53341 gactgggatc agtaaagcat agaatggaat cgtttcttct gccattccgt aagtagagcc
    53401 gcctaatgca aataacagca tcaatactgg aataagcatt ttttcttttc ctttgaattt
    53461 cttcacaact gaagcaatcc cggcatctag tgcccctgtt ttgttgataa tacctaaaaa
    53521 tccaccaaca accaaaatga agaaagagat tgggattgca gcaggtgttt ctttagttag
    53581 ctcccccgct ggtacaccta gcatcccatt gattggcgcc atgaaaatat cccacagccc
    53641 ttgaggattt tgttgtactc gttcatatga tccagcgacg atgttgcctg catcgtctac
    53701 actatagtgc ccagctggta taaaccaagt aagtacagcg attactgcaa taataataaa
    53761 taagaccgta tacgctgaag gcatttgaaa ttttttcttt tttgtttgtt ccatcttctt
    53821 cttcctttct tttccgttag agacaacaat tttggctcta atgttatttt atcaaaaaga
    53881 gtatcagaac aaaaataata acacgcattt tgtaaaactt ttgttcaaaa agttcgtttt
    53941 tccctattcc ctcctctttt ttcaggtttt taaagctttc ttctttttca ttgtagcgtt
    54001 tccttttttt tataaacaaa cattttcgtc ttttaaaagg agaagaattt cacatttgca
    54061 aagaattgat tgatttttat gcataaatca aaaaaatact caaaacaaac aaataaaacg
    54121 tttacattat tgcatgtctt gtattttttt ccaaaaaaaa agaccaagaa atttcttgat
    54181 ctttttgata tttatttgac tgctgtatga cgttgttcga actgatgttg ttttcgactt
    54241 aaccatggaa gaagttgcgc atgcagcact aaaaagacag cactcacgat gaatcctttg
    54301 atcaagttga aaggaacgat cccaatcagt acatagtttg ctaaagacat gcccagcatc
    54361 tgtgttgcgt tcagccctaa aaacattaag taaagaggcg taataacgaa ataatttgcg
    54421 atactcataa aaatagttag agcgatggtt cctgtaatga cacctaaaaa tttgtttctt
    54481 cctttatgct gtttctttac actaaagaaa taataaatcg ggaatgtaaa gatcgttgtt
    54541 gataagaaac tagcagtgtc tcctaccaaa ttatccggag aaaaacctgt agtcagcaga
    54601 tgtaatactg aacgcaagaa cgctgttgca actccggccg ctggaccgaa taagaacatg
    54661 ctgatcaata ccgagatatc actaaaatcg atcttcaaaa aactaaaagc cggcatgatc
    54721 ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa acatcgctac tgcaaccatt
    54781 ttctgtacac gggtgttctt catttgaaat cctcctgtta ggactcctct tcagcgaact
    54841 ttttgacgtt tctctccaaa tgaaaaaact ctattttcca gggaaaatag agttagagtt
    54901 atttgatcaa gcgtcgtcaa ataagctcta tcttctttat ccagactata ctgtcggtat
    54961 cggaatttca ccgattcagc tatttttttg caaaataggt cgtggactat aaccaccggt
    55021 cgggaatttc accctgcccc tgaagacgaa ccttatataa tttttgttta catattcatt
    55081 atacatatct attcaaaaaa cgcaacatct aacacttata aaaagtaagt gttcattttg
    55141 agtggttcag caaactgctg acttcttttt tgttcagttc acggtaatcc ccaggacgta
    55201 ggccttgtaa agtcagatct ccgtattttt cacgttttag tttttgcaca ggaagaccaa
    55261 ctgcttgaag catatttttc acttgatgat tacgtccttc gtggatcgtc aattccacga
    55321 tactgtggtt tgtcttagga tccactgata aaatttggaa tttagctgga gatgtttttc
    55381 gtccttcgat ctttattcct tttgtcaaag gtgcaagcat cgattttgta gcgatccctt
    55441 ttacctttgc aacgtaaact ttatccactt catgttttgg atgtgtcagg cgctgagcaa
    55501 aatctccatc atttgtcagt agcaagatcc ccgaagtatc gtaatccagt cgacctacag
    55561 gatagatacg ttcttttacc atcggcaaaa gatccgtaac aacttttctt cctttgtcat
    55621 ctgcaacagc agaaataact cctttaggtt tgtacaataa atagtaaccg tattcttctt
    55681 gataaattgg gacttcatcc acttccacag tgtcatgttt cccaactttt atccctaatt
    55741 cccttacaac ttgtccgttt acttttacac gtcctgcaag gatgaattct tctgcttttc
    55801 gacgagaagt gatgccagcg tgggcaatta ctttctgcaa tctctccatt acaattattc
    55861 tcctttattc attccatcaa agaatagatc tggtgacacg tcttcttcaa gtgaaatttc
    55921 catttcttgt gtatcaggca gttcttctaa tgatttcaaa ccaaaataat ctaagaagta
    55981 gccagttgtt ccatataata tcggccgacc tggtccttct actctacctt tttcttcaat
    56041 cagtttatgg gcagctagac gctgtaccgc tcctgaaacc tgaactcctc gaatctgctc
    56101 gatttcagct cttgtgattg gctgtttata agcgatgatt gctaaggttt cgacggcggc
    56161 ttgagataat gtgtttgatg tcccttgcgc atatcgctta agtaagggag ccagctcttt
    56221 tttagtcgtt aatacataat ggctttccgt ttcaaaaata tgcaaagctg agtgcgagtt
    56281 ttgagtgtaa gattctttta attctttcac taaacttgtg acttctgctt cgctgagatt
    56341 taacagtccg cttaattctt cattactgat cccttcctcg ccaacaataa aaagaagggc
    56401 ttcaagttca cttaatttcg tcatgttcgg tatctcctac tgctggataa agcataattg
    56461 attcatagtt ttctttttgt tgcgcaatga tctgcccttt tttcatcaat tctagcaaag
    56521 ccataaaagt agtgacaact tcacttttag aaggtgactc aaaaaaagaa tcgaaagtac
    56581 agccatgcgc atttcttttt atacgctctt cgataaatac cattcgttct tcgatcgttg
    56641 tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa tttcttacgt tctaagattt
    56701 tctgcatggc acggatcaaa tcgatttttt tgacttgtcc tcgcttcaac ggcttttcag
    56761 catccgctaa cccatcgatg ttcataggtt cttttgtgta ataaagactt cgttcctctg
    56821 ctttttctgt cagtctttca gctgcatatt tatatttacg gtattctaaa agctgagtga
    56881 ccaattcttc tcgaggatct tcttcccata attcttcatc gtctgtgacg aattcttgga
    56941 caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc agccatcact aagtattctc
    57001 ctgcaacagc tagctcgagt gttttcattg tatggatata attcatatat tgctccgtga
    57061 tcgtagcgat cggtatatca tatatatcga tttccatttg ctgaatcaga tgaagcagca
    57121 gatcgagagg accctcgaat acatctaatt taatattgat ctccgtcaac tcattcactc
    57181 tttcttcttt ttctttgcta gccattttcc aatgtaaggc tctgtgattt cagttgcacg
    57241 gatggagaca tccgggtact tttcctgtaa ttcatctaac atttgaaagc ccatattctc
    57301 accgcgataa gacggattca aagaaatgtc atggatgatc agctgatcgt tcgttgccca
    57361 gtaaatacca ataatccctt gaatgttggt tgaaccttct ggcgtaaaga aaaaaagttc
    57421 ataatcgtct tcagattcgt acgtatcaat ctccttcaac aaagaagttt tacctgtcag
    57481 tttcttatgg aaactcaata gtcccatagc aattttacgg ttttctttcc ggtaatgtgt
    57541 taacatcttc tcaccttcct atgactaagc ccttggaaaa tgctgcttat aaacatccgt
    57601 cattcttttc ttcgtgatat gtgtataaat ctgagtcgta gagatatccg cgtgacctaa
    57661 caattcctgt actgtccgca aatcagctcc attttctagc agatgtgtgg caaagctatg
    57721 ccgcagcgta tgtggtgtta cttctttgta aatcccagcc tctcgtacta actgcttcag
    57781 atttttccag attccttgcc gagaaagacc tttcccatga ttattgacaa atacatgcat
    57841 ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct aagtagcgtt ccagccattg
    57901 gatcgcataa tcacctaaag gaatgatccg ctctttatct ccttttccaa ctgtctgtac
    57961 cagtccaaga gaaagatgaa gatctcccaa tttcaatcca atcaattcac tgacgcgcat
    58021 cccagtagca tacatgactt ccaagattgc acgatctctt atccctaacg tttttgtcgt
    58081 atcaggtgct tcaatcagct tttctacttc tgtcagagtc aatgtacttg gtaatttctg
    58141 tgctttcttc ggcgtatcga tatgttgcat cggatcatga tcagtgatac gctcttgccg
    58201 taaaaactga tggaatcttc tgagacttga gatcatccga gtaacagttg ctgtcgcttt
    58261 tttttcttca tgcaacttct ccagaaaacg gatgactaaa aagcgatcga catcctgcca
    58321 tgaagcaatt ttctgctcct gtagaaaatg caagtactgt tccaaatcac gttcatagct
    58381 ttgtcgtgta ttggcggaca atccccgttc aatattcaag tagtggagat aatcgttgat
    58441 ttgctctttc ataataatcc ccctcatgcc tctctatcat atcagatacc gcttcattct
    58501 gatagtcttt ttccataatc tgagcaaaga aaaagccgtc tagacactca gacggactgg
    58561 tttctttttt ctttttcata gcattcctga cagattccat ggaacgttag ccgatgatct
    58621 tttactaaaa aatgataacg ttcttctact acttgctcca cttcaagtaa aagatcctct
    58681 tctacttcct cgatcgtgcc gcagttcaag catagtaaat gatgatggaa atgtttggcg
    58741 ccttcttttc tcaaatcata acgggctaat ccatcattaa aacttacttt atcgacaatt
    58801 ttcaattctg tcaagatttc aagggttcga taaacagtag caagtccaat ttccggactc
    58861 ttttttttca ctaaaaagaa gatttcttct gcagataaat gctctttctc attttccaaa
    58921 agcacaagca gagtagcttc tctttgcggt gtcagcttaa accccgcttc atgtagctgc
    58981 tgttttgttt ttttcatcgc cgaaatagca ttcatgacca tttactcaac cccaacaatt
    59041 tataataatt acaaataaaa aaagatataa cactatgtta attaaaatta ttataagcta
    59101 gttaagaaaa acatgcaagg gattctcaat tagatttttt gactagtttt gtcacaccgt
    59161 tttcttgtgt aatcaatcct tgtttcaaaa gattacctaa tgcgcgctta aatgctcctt
    59221 tgctgatacc aaaagctttc atgatttctt ctggatccga tttatctgta aagttgattt
    59281 gctgatctgc agaacgttct aaaatggtta aaatcatttg tgcatcatct gatatagctt
    59341 catatgctct tggcttcaat gaaagattca gtacaccgtc tggtcggaca ccaatcactc
    59401 gaccttttat ctgctcgcct agacgaggtt cattatatcg ttcagaagga tggataaacc
    59461 caagatagaa atcttccgtt aaaacgtacg tacctgttaa tttcaagcgg tatgctgttc
    59521 ctatcacatc tttgtttttc atttcttctg ttccatattt gcttaaagat ttgaatattt
    59581 tttcatctgc taaactgccc caaatacggt cttttgcatc aactctaagg gaaatcatca
    59641 agcgatcccc ttttttaggc catagctctg tcattgtcgg caattcatca agagatacga
    59701 caaagtcttt atctggaaga ccgatatcga caaacgcacc taaatctttt cgtgtagcag
    59761 taacgattcc aaaagcgtaa tgaccgatac ggcttttagg aatttgtgta gtgatccgat
    59821 tttcatgttt ttgattttgg taaccgaatc cttcaactgc ttcaccgatt ttgtgttcac
    59881 cttctgattt gcttaagcca aaggtttgtc cgtttttttg gacaaagtag tttttttcat
    59941 tttcatcaat aataatacct gtaaatatag ttgctaataa atcgttcatt tttttctccc
    60001 tctatagtga aaggttttct taatacattt ctttgctatc ataacataat gttatctact
    60061 tgaatagctg agccttggtt tggaaaggtg aaaaaaggag tatgacaaca gttgtgtcat
    60121 actccccttt ttcgaataaa cggtgttaaa cggcaggctc acagcctctt tcatttgcct
    60181 aaaattaatt gctcccattt cctccgaacc atccagtttt acagttgatg gttacgatgt
    60241 aaaatggcaa agcactttct ccaatgcctt tcatcaatgc agattttgtt gaagtggcat
    60301 atagattata atagccttcc ccattttcga ttctggcttt ttctaatctg taacctcctt
    60361 caacgatata tccacgttgg atacatgtag caatcacttt gctttggaca cctggtgccc
    60421 acgtccatgc tggattagat gcatcggcaa tatcacttgc tctggcagat ttgattggct
    60481 gattcgctga gtttgaagag gaaggggtcg aggatgccgc ttcttgctgt gctgcttgtg
    60541 cgaccgcagc ttgttgagcg gcttgagctg cagctgctgc ttgagcggct tgttttgctt
    60601 gttcttcagc tgcttttttc gcttcttctg cttttttctt ttcctcttct tcttttttct
    60661 ctttatcagt gagcatctta tctacttgtt tcaattgttc attcaactga gcagatagat
    60721 ctgtattttt cactttttct actgcttctt ttgccgtctt gtattggtcg cgtgttgctg
    60781 aatccactac ttttccgtct ttaaagacta tagctgtttt ttctttagct gtttgcaatt
    60841 cagcatattg atttttagct tctgtttgtg cttgttgaat caattttcca aaatctgtgt
    60901 tatccgtttc gattgcttgg atctctttat ctgctttcaa cttgatgtca tctgctagat
    60961 gatcatcgac gatggcaggt gctatgaacc actcattcac tttttggata tctcggatct
    61021 tagattggat atcttggtaa gttgtttcta actctgaata tcctttttca ttcttaagac
    61081 tggataaatc attttttagt tttgataaat cttgatgaat catatctgca cgaataaatt
    61141 gatggtgatc atctgtataa aaggcagcaa gtttctcatg aagttcttcc atttgttgct
    61201 gtctttttgc ttctgctgct acttcggctt ctactttttg atgatggtca taataagccc
    61261 agcttcctcc accgagtaga agtactgctg ctaaaacgag ataaggtact ttttttgatt
    61321 ttttcttttg cgctttatct ggatctgttt tttctaagtt tgattcttga tgtgtttttt
    61381 cagtatctgg cacgattgtt attgatttcg cttctgcttc aaacagctta ggctggttct
    61441 cttctttttc tatttttgct tcaagatcag taccctcttt gcttacagat tgattttcag
    61501 catcggattc actatttatt tcatcgggct ctgttgactt tttgtctgtg ttttcgagta
    61561 tttctttttt ctctgcttcc ggcagtttat tcgttttttc cttttctaat tgtttttcag
    61621 taaatacttc agttttttct gtgatatccg tttttacgtc ttttattttt actgtttctt
    61681 tacctgtggc gttttctcta tcagagtctt tttcagtttc ttgttccttt tctggctcta
    61741 ctttgttttc ctgtgcaatt ttttcactga tcattttgag cagctctttc gcgtgctctt
    61801 cttttgtatc ttcacgatgt gctttgatat aagcggatag tatcgaattt tcttcctcat
    61861 tatcgacgat ttctttcagt tcagctactc ttcttttttg ttttgattca agcgtttctt
    61921 cttgattctt tcctgattct tccgaagtct catgaacagt tgctttcttc tgttcatttt
    61981 tctctatatt agttacttga tcgtgagcag gtggttcttc gtcttctggt tctgcttttt
    62041 cgaataattc cattacagat tctagaggta aatctttcaa ttccgaccat tcgattggat
    62101 cgtttaattc tgtatcagga aagactgcat cttcagttga tttatcctgc atagctgcat
    62161 ctgtatttgt ttcttcaatt gattctttta tttgctgatc ttctgcagtt atttgatgac
    62221 cgcagtctgg acagatagta ttctgctcca tttttttcga tccgcaattt ggacattttt
    62281 tcatcactta gcgatcggct cctttactag gtttacgcta ccatttaatc tatcatattc
    62341 tatacgtcac gccaatagct tatttttagg atttacttaa aaataatgaa tgaatttcct
    62401 tcctatagaa aaaaaagctt gagactgcgt agtctcaagc tttttttctt ttaaaataaa
    62461 ccaaacagtt ttactgattt ctcttctggt caatagtcca cgcttattct aagaaatctt
    62521 ttaattgttt tgaacgagaa ggatggcgca attttcttaa tgctttagcc tcgatctgac
    62581 gaatacgttc ccgagtaaca ccaaatactt tccctacttc ttccaatgtt ctcgtccggc
    62641 catcatctaa accaaaacgt aagcgaagga cattctcttc ccgatcagtc aatgtatcta
    62701 gtacatcttc caattgttct tttagtaact cataagctgc gtgttctgct ggacttgttg
    62761 cttcctggtc ttctatgaaa tcacctaagt gagagtcatc ttcttcaccg attggcgttt
    62821 caagggaaac aggttcttgc gcgattttca agatttctcg gactttttct gttggaagat
    62881 ccatttccgc accgatttct tctggcgtag gttctcttcc aaggtcttgc agcaattgac
    62941 gttggatacg tatcaattta ttaattgttt caaccatatg aactggaata cggatcgtac
    63001 gtgcttggtc agcgattgct cgagtgatgg cttgacgaat ccaccatgta gcataggttg
    63061 aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc cttcatcagt cccatgtttc
    63121 cttcttggat caagtcaagg aactgcatgc ctcgtcctac ataacgttta gcgatactta
    63181 ctactaaacg aaggtttgct tctgccagac gctgtttcgc ttcttggtcg ccttcttcga
    63241 ttttcaatgc taacgctact tcttcttccg cagttaaaag ggagacacgg ccaatttctt
    63301 tcagatacat acgaaccggg tcattgattt ttacaccggt tggcgcagaa agatcttctg
    63361 tttttgcttg ttcagctttt ttctcagcac tcttcaagct gtgaattgat ggatcaccat
    63421 tttcatccac cacactgata cctgcgtctt caatcttttg gatcaatttg tccatttcat
    63481 ctgcattcaa agtgaatggt gtagcaagct gattggataa atcatcatat acaacttgtc
    63541 gtttgggttt gttttctttg atgaaagctg ctactgctgc ttcatacgtt tttttatctg
    63601 ttccatttgc cataaaagaa ggcccccctt gagtagctat ttggcttgtt ttaactgttt
    63661 cgttaaattg atgatttcaa tcgtcaattc aagctcaagc tgtttgtttc cagttcgtct
    63721 ggcttcttgc tgcatttgtt tttttaatgt tatttcatca gctaagccag atttgctgat
    63781 cacatctagc aagtcttgga tttctcgtgg cgaactttct tctgccaccg gtaaatattc
    63841 gatttccacc accaaccgcc ttaaattttc atcttgcaaa aagtctaaaa actctgcaag
    63901 gttgaattca taatgttgtg agacatatgc atcgaataaa aaataaactt ctgcatatgc
    63961 atcatgaata aactgaaatt ctcgttcttt taaaatatta cggacagaaa cttctttaaa
    64021 tgcacgatat aatagaatct gctctgcctt ttctacttgc gtcaaaggtc tctttttccg
    64081 tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc tgaggttctt gacgattttg
    64141 ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc gtctctctgc cgatctgaaa
    64201 ctctgttgac agttgagata gatacatatc ttgttcgatt ggtgaaacaa ctcggctaag
    64261 ttcaactagt aattcttcga ggtattcgat cttgtctttt tcattatcta aatttttccc
    64321 ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg cgcccatgag ccactaattc
    64381 ttggaaagat gcttctccat acttacggag atattcatca ggatcaagct tttctggaac
    64441 gactacgaca gaaagtgcta atcgactgtt ttgccgaagc aattcaatcc ctcgattggt
    64501 tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc aattctttcg tcagcttttc
    64561 catttgttgg atctgttgag ctgttagact tgtccccata gaagctaatc cagttttgat
    64621 accagcctgc catgcagcaa tcacatccat aaacccttcg aacaacaaaa tttctccgtt
    64681 tttccggata tcgcttcttg ctttatcaag attaaataaa acttgtcttt tattgaacag
    64741 ttctgtttct ggactattca agtatttggg ctgatctttt tcctgccctt tttcaggtgc
    64801 aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa ttacgaagtg gaaacatcac
    64861 tctttgataa aaacgatcag acatacggcc atcatcatgc gtgacaaaca atccagagcg
    64921 ttctaacaat tcatttgaaa ttgattcatt cttgaatact tgctgaagaa aagaacgctc
    64981 attaggtgca aaacctatgt tgaattcttc aattaattct aaagacaacc cacgactttg
    65041 caaatattct aaagctggct gtccagcttt tgtatgcaat agcatgtgat gatagatttc
    65101 cgctgctttt tcatgagcag caatcagttt ccccgtagca gattcaggat tttggacagc
    65161 tatagtacgc tgacgccatt gatcttctaa cggtatctgt tcgaagtctg ccacttttac
    65221 cactgcttct ggaaaactta gaccttctag ttcttgaaga aaagtaaaca cgtttccgcc
    65281 tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct gcaacagaaa aagacggtgt
    65341 acgttcttca tgaaaaggac acagccccaa gtaattttta ccagactttt tcaactggac
    65401 atattgtcca atcacctcaa cgatattcgt ttgactgcgt actgtttcga taacctcttg
    65461 aggaatccgt tgagccattt tttcaccccc tgctctattg atatcttttg ggtttaacag
    65521 aagatatttc aggagaataa ccggtaaaaa atcgcactaa ctgaaatcag tgcgatttta
    65581 aaggacacaa ttatacatgt ttgattgtat catatttcat tgctttttca agtataacac
    65641 atttctatct cattaagcat caatttgcta ctcttttcag taactgattt tgaatatcag
    65701 ccttccagta caatactcga agaacaatat ttacgagcat gaatacaaag aagtatccta
    65761 cgctctctcc caaccctaag tttacttcca aaattccatg gaacagcatt gcagctacat
    65821 atatccctac gatcgtcgtt actgctagga agatgcgcaa tgggttgaag ggataacaag
    65881 cttttacaac tgccatgcaa ctgatcccaa tcagcaagta atacatcaaa gtagtagttt
    65941 cagcatttcc ccatgcgaat gtttttccaa gtagatacac cgcaatgata ttcactacta
    66001 caagcaaggc atttggtaaa gcattaataa gtgctgtagg caaataacgg taagtgattt
    66061 ttcttttatc ttgttcaaaa gataaaaaga aggaaggata cccttcaatc gctaaatcaa
    66121 tcagcgtgat ttggataggg ataaacggaa atccaattgc tgtaacggca catataatcg
    66181 ataaaataaa tgaataaatc gttttgataa aaaagatgcc tgagactttc gtcacattgt
    66241 tgaccactcg gcgtccttca aacaggactt ctggcaatgt agtaaaatca gagtccaaca
    66301 ataccagatt cgcaatctga cgtgttgctc catcaccttc tgccatagca atgctgcaat
    66361 ctgcttctct taacgccaaa acatcattca caccgtcgcc tgtcattgca accgttctgc
    66421 cgctttcttt caattcattt accagcaatt tcttttgctg cggactcact cgtccaaaaa
    66481 ccgtatagcg atgagcagct tctcgcactt ccatttcttc agtaatttga gaaagatcga
    66541 catacgcatc ataattcggt aatcctgcac gtctagcgat attggagaca gtaaaaggat
    66601 tgtctccaga aatcactttc agatccacac cttcctcatg aagataagct agtgtttctt
    66661 gagcgttttt tcggattgga tcatcgattt caaacagagc aaccggctca acaaatgctg
    66721 gtttttcttc gttcaattgc tgatttggag cgatccccaa cataagtacg cgatagccat
    66781 tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc ttccaccaaa cgttcaggcg
    66841 ctcctacgta cacgactccc agttctggaa attccatcgc gccccatttg cgatcagaag
    66901 aaaatgcgac tttgtttgtc acatcatacc gattagaaag ctcaaaataa tctctcatag
    66961 cccgcatagt gatgttgtta tcactgcttt ctgccagata cgtccccata atttctggga
    67021 tggctttctc gtacagcgga tgtagtgctt ctacccgctg gatactcatt ttcccttcag
    67081 taatggtccc tgttttatcc aagcataatg tatcgacatg ggccagcgtt tcaattgaat
    67141 acatgtcttg aacaaggatt cgtttttttg ccagtttggt tacccctgtc gttaatgcaa
    67201 tacttattag caataccaaa ccctttggaa gcatgcctaa caaagctgct gcagatgcaa
    67261 taacagaaat tttgatagaa gcatcgcgga tgaacagtgc ttccaaaaat agtatgatcc
    67321 ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt gcgaatcgaa tctacaagtt
    67381 cagaacgaat agctttgtga gtctttgcct cgctagtcaa gcggacagca taattatctg
    67441 cacctactcg gataacttca gccatgacag aaccgcttgt caaaaagctt ccagaaagca
    67501 attcagctcc agtttctttg acaatcaaat cagattcgcc tgtcaaaaga gcttcatttg
    67561 cttctgcccg tccagatata acctgtaaat cggctggtat ctgttctcct gctccgattt
    67621 ttaccaaatc tcctaatacc agctctttag tagaaatcga ttgttcttta ccgtcccgga
    67681 tcactagtac ttctgattgg gaaacaatcg ataatttccg tacaagattt cttgcatgta
    67741 tttcttgata aattccaata acgatattga cgacaataat tgctaaatac gccatgttgg
    67801 aatacgcacc tacaaataac agacaaatcc caataccaaa gttcagaaaa ttgaataacg
    67861 tcaatatatt atcgctgaat atttgttttg tactttttga tgcatcttcc tggtagtcat
    67921 tttgctggcc agaagccatt ttctgaacta cctcttgctg tgtaagtcca ttcattttct
    67981 ttttctccat tttccgccaa ctttcaaaaa taatcacgtg tttaagtcta gcgtgttcca
    68041 agattaaaaa caacttgttt ttataaaatt tatagaaaaa cacacgaatg attttacaaa
    68101 aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt ttttattatc aatctatctt
    68161 tacttatatt gttcctccaa acggctcatc caccaaccta gtgctgtacc ggctataaaa
    68221 agaacaggac aagctagtac cccagcaact cccaatcccg cgtaatcggt aggaatgatc
    68281 ataatcgttg aagcaaaaac tacacctaaa atgaaatgga atagcttgct atatgccttt
    68341 gagaaaatgt aatccatgat ttttgacaat ccaagaacac aaagaatccc accaattccg
    68401 atcggcacaa tcacttcaag tcgtacttct ttaaatccgt cagccatcgc tttatacaat
    68461 cccatataca ccaaaaaatt agaagggctc aatcctggga cgatcatacc caaaccaatc
    68521 aatccgccgg caatcagcca tgttccaaaa ttctgatcga cttgcccgtc aaataattga
    68581 gcgccgtata ataaaaacaa ataagccaga acaaaagtaa caaccatgat gatcacatca
    68641 gaagtatctc ttcctttttt ccctgcttct ttccataacg caggaacagt tccagcgata
    68701 catccgacaa aaaaccataa tatcgttgtt tcatacgcac ctaataaaaa actgactaaa
    68761 aaagaaagta gaaagatgcc tgtcactccg cctagaccaa caggcagaaa aaacaaaaca
    68821 ttttctttga aattttttgt aaggtgggct aaaaaagaaa tcagccgctc atacatgcca
    68881 aagacagctg ctaatgcacc accgctgact cctggcaaga taaatcctga accgataaac
    68941 attcccttca caaaccgtaa catccagtct ttggttgtgt accccacttc ttgattttcc
    69001 attttttgcc ttttttccac tatttgcgta ctccttcttt catttaattt tattcatgat
    69061 tgaacatttc ctgctatttt acttaaagac tttttcatag gtctctatta ttttttcatt
    69121 cattttgaca atatcaggat aaaacatgtt acctccatta tgatagagat agccgccatt
    69181 gtaaagcaag gactggatcc gccaatatcg gtattgtttc ccttcctcat ttcctaaaag
    69241 tgggctcagc acatctttag aatacgcttc tgctaattct actgtgtttt ctccgccatg
    69301 attttttaca taggcaatat aatctttccc aaaattatat gcttggacag ctgtccataa
    69361 atcgcatcct tgtttctttg cttctactat catttccgcc aaatatttga caccttgatc
    69421 aatactgtca gctggattat caatgatctc agcttctcca tgcagacttt ccgagctctg
    69481 catgagatct gtcccttttc cttttgattc ggtcaatatt atcgccttga tcaaattctc
    69541 gtagttttcc atatgataat tttttgcagc tgttgttatt tctatttgat agctttccac
    69601 tcgttttacc gaacgataag ttcttcctca taaaaacaac accgcaccaa taaccgtcag
    69661 aatgatcatg taaaaaagaa tacggataat agataatcgt tttcgcttca tttcatcacc
    69721 tagttatttt gacatctttt tttatcttac tatttcttta tcttcttggc tatttcttcc
    69781 ttgatttctg tgtacgcctt aagaaaaaat gaattttcct gtattttttg acatcttacg
    69841 aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg actgatataa tcgttatact
    69901 ttacacagta ggtgattatg tgaaaaaaga aaagaaatat gcaaaaatgc cagatgggag
    69961 cgaaatttac tatgaaaaga gcggtcaagg cttccctctc tttttactgc atggcaatga
    70021 cggcagcggc cgcttttttt cagaacaggt ccctgtactc gaacgctact ataccgtgta
    70081 tctagtagat agccgaggac atggtcgttc gacaaacgaa gcatctatgt tgaattttca
    70141 gttaatggcc gaggatctga atacgatcat gttgctggaa aaaatcgatc aggcagattt
    70201 tcttggattt agtgatggag caaatctagc actggtattt gccagcagct tccctaaaaa
    70261 agttcatcga ttgattttaa attctggaaa cacgcttgtt aaaggcgttc gtttttctgc
    70321 cagagtcatc agtaatattc attatgcatg ggtatggtta ctctctttat ttcgcccaag
    70381 tcttcgcaaa aatcttttag ttatcaaact tttgctgcat gacatcgggc ttacagaaaa
    70441 tgatttaaaa aaaatcaact cccccacttt gatcatcgtg ggaaaaaaag atgtaatcaa
    70501 gctaaaacat tctttgtata tagctaaaac tataccaaaa gcttcctttg tgcttgtgaa
    70561 agaacaagga catgaattag ctagaaaaga tcctgaacgc ttcaatcgag aagttcttca
    70621 atttctttct gaaacataac tattaggaat agaaggtgat ttatttgtta aaaaatacca
    70681 tacaatggct gaaaaaccac ctaggactgt tcaaaacaat ctttttgatt tctgtcattg
    70741 tcattattgt cggtgaattg atgtccatcg gtaaaactct atctatccag caattaggag
    70801 aaacgtttgc cactatacct gtatggaaaa gcggactaat gctattgatt ggtcttatct
    70861 ctgtgttacc tatggttggt tatgatatta ttttgaatcg gatgcttgaa caaaagcaga
    70921 atcctcgtta cctgtttgag acaagctggc tgatcaatac gatcaacaat attgccggtt
    70981 tcggcgggtt tgttagtgtg gggcttcgct ctgaactata tggacaaaag aaagagagca
    71041 gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt gatggctgga ctttctattt
    71101 acagtctgct ttctttttta cttgtagtct tcacgccagt tgctcctttt ttgaagcaat
    71161 attggatatg gttgatcggc ggcggtctat attttcctgt cgtcttttta tttactactt
    71221 tcaaaaagaa aggattcctt ggtggtacct cacttaaaac tcaaggacag ctattgctag
    71281 tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct ttctgttggt tatttaatgg
    71341 aaatccggat tgatctgtgg caaacaattc cattattcat tgctgcttca gtgataggaa
    71401 tcgtgtctat gattccagga gaaattggga gtttcgatgt aatgatgatt atcgggttgt
    71461 ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat cttgctctat cgcctgttct
    71521 actacatcat tccgtttttg attggaatcg tctttttctt caaaaatatc ggttccactt
    71581 ttgatcagcg ttattctggt atccctaaac aattagcaac agaaattgcg cataaaatcg
    71641 tggttgtctt attatacttt tctggaatca tgctagtact ttctgccact atcccgcaag
    71701 cttttacaga gtttcgctgg cttcatagtt tgaacccatt gaaatttcat tttattatcc
    71761 aatttcctag tatactattg ggatttcttt taatcattat gggcagaggg atcgcagcac
    71821 gtgtgaaacg agcatatttg cctacaatct tcttgattgt tctagcttta ctttatgttt
    71881 tattaagtga ttttagtttc acaccggtgg ttttcttgtc tattctgctt ctgatcattc
    71941 ttgcttctaa aaacgaatta tttcgggaac aattgatcta ttcatgggag tggcgtacga
    72001 tcgatggaat cattattggt gcactgtcct tgctttacat cgttattggg gtatacaatc
    72061 tgccggattt ccctcatcgg cgtcaccatt ttatttcctt tttcttattt ccttctgaaa
    72121 agatttggtt ttcgggattg ttggccatca tcgctgttag tttcatgatc gttctatttg
    72181 ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc ctttaatgaa gaaaaggccc
    72241 tgaagatcct tacaacttat ggaggaaact ccgatagtca attgatcttc ttaaaagata
    72301 agcggatgtt tgcctatgaa aaagacggtg aaccaactgt tcttctccaa ttcgcttgct
    72361 tcaataataa atgtattgta atgggtgatc cttctggtaa gaaagaagat tttccagaag
    72421 caatcgaagc ttttatcgaa gaaacagatc gactatgcta tttaccagtt ttctacgaaa
    72481 caagcgaaga gattgttatg attttgcatg aattcggcta cgatttcatt aagatggggg
    72541 aagaagctta tgtagacctg aatagtttta caacttcagg gaaaaaaatg aagggcactc
    72601 gtgctgtctt gaatcggatc gaacgagaag gatttacatt tgatgtctta caaccaccat
    72661 tttctactga gcaaatgagt actttcaaaa atatctctga taattggttg ggttcacgaa
    72721 aggaaaaagg gttttcttta ggctttttct ctgaagatta tctacaaaga gcgcctattg
    72781 cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc aacgatcatg cctacttaca
    72841 cgaacaataa agtaggaacg attgatctga tgcgatatga ttctaaaaaa gcaccttctg
    72901 gcagtatgga tttcttgttc ttgcatttgt ttgcctatat gaaagaagaa catatccaat
    72961 ggttcaattt agggatggcc cctctttcaa atgtcggaac ttccagaaag agttttttac
    73021 aggaaaggat tgcatacttg gtttacgagt ttggttctca tttttattct ttccatggat
    73081 taagagaata taaaagcaag tacgctacaa actgggtctc acgttatact ctatattcta
    73141 gagatagttg gattgcatat gttatgattg ctttgctgat tattgataat gcgccagttg
    73201 agcagacaca aggtagaata agtggtttga aaaaatggat acgaagaaag tattaaaaac
    73261 tgcataccga tagatgaaca ctctcatgat gaataaaaga gactgaagta aaacgaaagt
    73321 tcatgcttct acaatctctt cttatacaat tgaagaacaa agagcggtcc aaacagaaat
    73381 cctgtttgga ccgctctttt attttaaaca tttttcatta ccaaaatatt cgagtcgcgt
    73441 ttcttatgct tcgatctctg taacgatacc tgaacctact gtccgtccgc cttcacgaat
    73501 tgagaatgtc gttccgtttt caacagcgat tggatggatc aagtcaacat caatcgtcac
    73561 gttgtcacca ggcatgacca tttctgtatc ttctggcaat gtgattgttc ctgtaacatc
    73621 agttgtgcgg aagtagaact gtggacgata gttgttgaag aatggagtat gacgtccacc
    73681 ttcttctttt gtcaacacgt acacttctgc tttgaatttt gtatgtggag taatggaacc
    73741 tggtttagca agtacttgtc cacgttcgat atcgtcacgt tggatccccc gtaacaacac
    73801 gcctacgtta tccccagctt ccccgtaatc taacgtttta cggaacattt ctacacctgt
    73861 tacaactgct ttttgtgttt caggtttgat ccctacgatc tctacctcat caccgacacg
    73921 aacagcacca cgatcaatac gacctgaggc aacagttcct cgacctgtaa ttgagaagac
    73981 gtcttccact ggcaatagta atggtttatc tgtatcacgt tctggtgttg ggatatattc
    74041 atctactgta tccatcaatt ccataatagc agcttcagca tctggatcgc cttgcaatgc
    74101 ttttaatgcg gaacctttga tcacaggagt gtcatcgcct gggaaaccat attcgctcaa
    74161 taactcgcga acttccattt ctaccaaatc gatcaattct tcatcatcga ctaaatcaac
    74221 tttgttcaag aaaacaatca ggtattttac accaacttgg cgtgacaata aaatgtgttc
    74281 acgtgtttga ggcatcggac cgtcagttgc agaaacaact aagattgcac catccatttg
    74341 tgctgcccct gtaatcatgt ttttcacata gtccgcgtgt cctggtgcat caatatgcgc
    74401 gtagtggcgt ttttctgttt catattctac gtgtgcggta ttgatcgtaa tcccacgttc
    74461 acgttcttct ggagctgcat caatactagc atagtcttga ggatttgcta ggcctttttt
    74521 gcctaatact gtagtgatcg cagcagttaa agtagttttc ccatggtcaa cgtgtccaat
    74581 cgtaccaatg ttaacgtgtg gtttacttct gtcataatgt tcttttgcca taatttacaa
    74641 acctcctaaa taatatagat cactgaaaaa tttcagctct caccttttta ttatagtctt
    74701 tttttgacta aatcaaaaag aatacgtccg acttactttt tgtaagattc gaactaagct
    74761 tattatacgt caatattggt caaagtcaac taagagcact cgtctgtctt atacgcgaaa
    74821 aaagtacctt ttataaataa aaaaatgtgt tttttgagaa aaacttcaag atagtcctta
    74881 actttctttt gaagcaataa gaacaaaatg aggaaaagtt taaaattcag ctgttgccaa
    74941 caactttcaa tagacgaaat cttctatttc gttaataata aggaaagagg tgaagtacat
    75001 gaaaaaatta attggcgtac ttgtcgtttt aggcatattt ctcggcggaa gttttgcagc
    75061 ttatcattat ttttacggcg gcgaagctta ttatacaaaa atcacgacga atggcgaaat
    75121 gtcagctacc caagcagata acggagagaa attcacgact tatacctaca agcaagcggc
    75181 ttataataaa gatggtgaaa aaaaacaggt gacgcttcgc gaagaaagag aacatccatt
    75241 aaagatgaat gcgtatctta aactcaaagt caatcctcgt aaaggtgtat taagctggga
    75301 agaaataaag gcttctgaag tgcctaaaaa tgcggcagaa aaaatcgata attagtaaat
    75361 ggtcttaaaa ttttattaga taaaaagagg ctgggacaga agcgtttaac tccaagaaat
    75421 aagaaggagt tgcttctgct tccgccgttt atacgtgttt agagcgtgag acaaaagtgt
    75481 tctttacttt tgtctcacgc tctttttttg ttatattcgt cttttccgat ccttctcttg
    75541 acacaattca tttaactgat cactggtact tgaacaccta atattctagt catttttata
    75601 aacgattcaa tacttcatcc acatttttga tcatcacgga tatcgtacca tccggattat
    75661 tcacaaattc aatcaaatct gggttgcgat atacatctac tggtacgatc agttcgatcc
    75721 cgtttgatag cttgaatttt tgttttccaa attttttctc agaaatttct tgtacttctt
    75781 ttacaggagg tgcttctggg acaaatcctt gctcttgtac ttcttcttta aaagccattt
    75841 ttgccgtgat gttttccttg aagacttttt ccgcaatcat ctcatgatcc aaccgacctt
    75901 tttcttctat cgtatcatag acagcttctt tcaaatcagc catgatatca aattcttctg
    75961 tctcaaattt ttttccaaga tgcttggcta ctttttggat cacttttaca ttttcttcta
    76021 aagaaggtgc aggaacactt tcgatcactc ttccagaaaa ataaagctct tttttgccag
    76081 aaaactcata ttttttttca attaattcgt aggtccaatc agtcaaattc acagcgaatg
    76141 cttcatctgc tttttgtgtt ttcgccccta gaattgctcg attcaaaatc aagcggttgt
    76201 cgatccctgc ttcgtctgct tcaacaaagt gagtgtaagc ctcacgataa ttgactttca
    76261 ataaagataa gtacatcact gtatctaatt catacaagac aacaaataca tctgcactag
    76321 gtgcttcttc actttcttgg tagatatcga accaccgctg aacgattgct tcacttgctt
    76381 ccacaaaatt ttcttgagcg attttaagtg attcaacgat catgctttct tctgctagtt
    76441 gtccagtttt tgtttgagca gaagagattt tttggatctt cttttgaaga aaatcacgaa
    76501 tatattcttt tgtcagatcc agctcttttt gtgaaaagac tggagaacca gtttctctgt
    76561 caataatatg cagaattgct ttttttaaat agatatccat tttctcattc ccttctgtct
    76621 tagtttacgg aaaaaaaatc aaaaatacca gaatcaaaat cattttcttt taaacaaaaa
    76681 tttcaagagt agaaacaaaa tggattcttt ttttcgaaaa atgcgctaca cttatagttg
    76741 aacgaataaa aaaggagctg aaagtatgaa ttcattaaca agcacttatc gtctatcaaa
    76801 tggttacgaa atcccggtag taggattcgg cacatggcaa acacctgatg gggatgtcgc
    76861 tgtttcctct gttaaagaag cgctggctgc aggttatcgc catatcgata ctgcccaagg
    76921 atacaagaat gaagaaagcg tcggccaagc gattaaggaa agtggaattc ctagagaaga
    76981 gatattcttg acaacaaaat tatggaatgc aaaccacagc tatgaacttg tgatgtcttc
    77041 ttttgaagaa tcattgaaga agctccaaac agattattta gatctgtttt tgatccactg
    77101 gccaaaccct gttgcttttc gtgataattg ggaacaagca aatgcagata catggcgagc
    77161 atttgaagaa ctgtatgaag caggtaaaat caaagcaatc ggtgtgagca atttcttacc
    77221 ccaccatcta gatacactag caaaaacagc aaaaattatg ccgatggtca atcaagtttt
    77281 ccttgcacca ggcgaattac agacaactgt agttgagtat gcaaaaaaac atgatatgat
    77341 cctcgaagca tatagtccat taggcactgg taaaatcttc gatgtgcctg aaatgaaaca
    77401 aatcgctgaa gcacatgaca agacgattgc acaagttgct ttgcgttggt cgctgcaaca
    77461 cgaattcctt cctcttccta agtcagtgac accaagcaga atcaaagaaa atactgaatt
    77521 atttgatttt gaattaacag aagaagaaat gaaacaaatc gatcagttag atggtgtagt
    77581 cggcaaagca aaagacccag atactaccca attttaagtc gaaaggtgat tttatggatc
    77641 caatcgaacg cttgaattct ctctcggaag aagttaccca gacttttcat tccgattttg
    77701 tctttttgat cgatgcagag aaaatccaac attttcctgc aagaaactgg acacatgatc
    77761 aaatcatcga agaactgaaa aaacggttcg atcattcgct aatggtcaaa ccctggcacg
    77821 aacatgaagt catttattca cctgaactac ctgtttttgc cttgataccg aaaaaataga
    77881 aagaatggaa cggattatgt atatatacat aatccgttcc attttttatt tttctttcaa
    77941 aaaacgggaa aatacgcaaa tttttctgtt gtaatttgcg tatacgcaag tttttttgca
    78001 ttactccttt tcatttggct gtttttttct tataatcgaa agggtatgag cgaaggagag
    78061 aacatatgaa gaaaaaacag aaacaaaaat tattaaatca attccgtcct tcattggatg
    78121 gtgtaagagg acaattattc cgttctctag aagaagagag cttgcgacgt tatggtttgc
    78181 cgttacaagt catgcttgat cccaaaaacc gtcaaatctt aacgatcgga ttagctggga
    78241 aaacaaatga agatacacgg atcaacgtgc caatcgatga caacttcaat actgtattaa
    78301 agagaattcg ttcaggagaa aacgggattt tcgaacgatt ccgtgacaat cttcttattg
    78361 aaatcgtgtc ttactggaat gatcaacgat tgaaaaacga tgaaccaact gcgcaagctg
    78421 ttgcgacacc agttacagaa gaaacagtca gtgtgccaga agaaaaaacg gaaaaaccaa
    78481 aagcggacac aactgaaaat acacgctcaa ctgatacgaa tgccgcttta agttttgctg
    78541 atttttcaaa agccgttgct gagtatccta aattttacac agaacaaaat gaacatgaag
    78601 tagttattaa tgaaaaaaat gctgatgaac ctcgtaaatt agcaactatt tctatgacta
    78661 ctgaaaatga gttcgttatc gaaaaagcac tcgaacggaa atacaaagtc aaattgactt
    78721 tgattccttt gatcgaacaa tttgcagcga cagcgattac tgatcgataa aaattctatt
    78781 tgtcataaaa ggctgggatt taaaatccca gcctttttag tcatataata atttctacag
    78841 caagtaaaaa gaaattcctt ctaacatcag gctcaaatat cagcttgacc tgtccaacaa
    78901 atcacctatg atcctacaat gttaggcgac ttctcttcta cctgaagata tcttggagtt
    78961 gcctgatttc ttaagatgcc taaccttaac tataaaaaat tctaataata aacatatttt
    79021 ctgatagaga aaaaagcggt tctataatat tttgtgttgg tggaaaatcg aaagcgattt
    79081 tctactaaca cttttttctt cgtttcaact caaaaagaga ctcacttttg gtaaaattta
    79141 gtcgaccaaa acgtcaccct accaaaggag tctctcaatg gataatcata ctagaaaatt
    79201 actcg
//
LOCUS       DADVXV010000002        73848 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.002, whole genome shotgun sequence.
ACCESSION   DADVXV010000002 DADVXV010000000
VERSION     DADVXV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 73848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.002"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(56..1534)
                     /locus_tag="KB969_000074"
     CDS             complement(56..1534)
                     /locus_tag="KB969_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6868097.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1832..2767)
                     /gene="murB"
                     /locus_tag="KB969_000075"
     CDS             complement(1832..2767)
                     /gene="murB"
                     /locus_tag="KB969_000075"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBB6868098.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2840..3760)
                     /locus_tag="KB969_000076"
     CDS             complement(2840..3760)
                     /locus_tag="KB969_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6868099.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3873..4625
                     /gene="xth"
                     /locus_tag="KB969_000077"
     CDS             3873..4625
                     /gene="xth"
                     /locus_tag="KB969_000077"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBB6868100.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5489..6022
                     /locus_tag="KB969_000078"
     CDS             5489..6022
                     /locus_tag="KB969_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBB6868101.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6512..7036)
                     /locus_tag="KB969_000079"
     CDS             complement(6512..7036)
                     /locus_tag="KB969_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868102.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(7029..7502)
                     /gene="tsaE"
                     /locus_tag="KB969_000080"
     CDS             complement(7029..7502)
                     /gene="tsaE"
                     /locus_tag="KB969_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBB6868103.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7625..8605)
                     /gene="pta"
                     /locus_tag="KB969_000081"
     CDS             complement(7625..8605)
                     /gene="pta"
                     /locus_tag="KB969_000081"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBB6868104.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8758..9438)
                     /locus_tag="KB969_000082"
     CDS             complement(8758..9438)
                     /locus_tag="KB969_000082"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6868105.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9564..10433
                     /locus_tag="KB969_000083"
     CDS             9564..10433
                     /locus_tag="KB969_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6868106.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10459..10974
                     /locus_tag="KB969_000084"
     CDS             10459..10974
                     /locus_tag="KB969_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868107.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(11021..11614)
                     /locus_tag="KB969_000085"
     CDS             complement(11021..11614)
                     /locus_tag="KB969_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868108.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11639..11818)
                     /locus_tag="KB969_000086"
     CDS             complement(11639..11818)
                     /locus_tag="KB969_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868109.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(11895..12404)
                     /locus_tag="KB969_000087"
     CDS             complement(11895..12404)
                     /locus_tag="KB969_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868110.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12500..12880)
                     /locus_tag="KB969_000088"
     CDS             complement(12500..12880)
                     /locus_tag="KB969_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6868111.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13210..13959
                     /locus_tag="KB969_000089"
     CDS             13210..13959
                     /locus_tag="KB969_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBB6868112.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14143..15420)
                     /locus_tag="KB969_000090"
     CDS             complement(14143..15420)
                     /locus_tag="KB969_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868113.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15499..16143)
                     /gene="pcp"
                     /locus_tag="KB969_000091"
     CDS             complement(15499..16143)
                     /gene="pcp"
                     /locus_tag="KB969_000091"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBB6868114.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16342..17286)
                     /locus_tag="KB969_000092"
     CDS             complement(16342..17286)
                     /locus_tag="KB969_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBB6868115.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17288..17974)
                     /locus_tag="KB969_000093"
     CDS             complement(17288..17974)
                     /locus_tag="KB969_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBB6868116.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18448..18768
                     /locus_tag="KB969_000094"
     CDS             18448..18768
                     /locus_tag="KB969_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBB6868117.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            18922..19827
                     /locus_tag="KB969_000095"
     CDS             18922..19827
                     /locus_tag="KB969_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6868118.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19824..20597
                     /locus_tag="KB969_000096"
     CDS             19824..20597
                     /locus_tag="KB969_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6868119.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20778..22202)
                     /locus_tag="KB969_000097"
     CDS             complement(20778..22202)
                     /locus_tag="KB969_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6868120.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22413..22859
                     /gene="nrdI"
                     /locus_tag="KB969_000098"
     CDS             22413..22859
                     /gene="nrdI"
                     /locus_tag="KB969_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBB6868121.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(22924..24906)
                     /locus_tag="KB969_000099"
     CDS             complement(22924..24906)
                     /locus_tag="KB969_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6868122.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(24920..25816)
                     /gene="murQ"
                     /locus_tag="KB969_000100"
     CDS             complement(24920..25816)
                     /gene="murQ"
                     /locus_tag="KB969_000100"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBB6868123.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25819..26880)
                     /locus_tag="KB969_000101"
     CDS             complement(25819..26880)
                     /locus_tag="KB969_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6868124.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(27091..27657)
                     /locus_tag="KB969_000102"
     CDS             complement(27091..27657)
                     /locus_tag="KB969_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6868125.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(27685..29187)
                     /gene="eat(A)"
                     /locus_tag="KB969_000103"
     CDS             complement(27685..29187)
                     /gene="eat(A)"
                     /locus_tag="KB969_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6868126.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29445..30566)
                     /locus_tag="KB969_000104"
     CDS             complement(29445..30566)
                     /locus_tag="KB969_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6868127.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            30692..31633
                     /locus_tag="KB969_000105"
     CDS             30692..31633
                     /locus_tag="KB969_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6868128.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31783..32679)
                     /locus_tag="KB969_000106"
     CDS             complement(31783..32679)
                     /locus_tag="KB969_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6868129.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            32948..34288
                     /locus_tag="KB969_000107"
     CDS             32948..34288
                     /locus_tag="KB969_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6868130.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34506..34949
                     /locus_tag="KB969_000108"
     CDS             34506..34949
                     /locus_tag="KB969_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6868131.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(35453..36871)
                     /gene="nhaC"
                     /locus_tag="KB969_000109"
     CDS             complement(35453..36871)
                     /gene="nhaC"
                     /locus_tag="KB969_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6868132.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(37274..38497)
                     /locus_tag="KB969_000110"
     CDS             complement(37274..38497)
                     /locus_tag="KB969_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBB6868133.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(38528..39367)
                     /locus_tag="KB969_000111"
     CDS             complement(38528..39367)
                     /locus_tag="KB969_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6868134.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(39384..40064)
                     /locus_tag="KB969_000112"
     CDS             complement(39384..40064)
                     /locus_tag="KB969_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868135.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(40066..41139)
                     /locus_tag="KB969_000113"
     CDS             complement(40066..41139)
                     /locus_tag="KB969_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6868136.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(41195..41433)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(41476..41709)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41786..42457)
                     /locus_tag="KB969_000114"
     CDS             complement(41786..42457)
                     /locus_tag="KB969_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6868137.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(42544..45222)
                     /gene="mgtA"
                     /locus_tag="KB969_000115"
     CDS             complement(42544..45222)
                     /gene="mgtA"
                     /locus_tag="KB969_000115"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBB6868138.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            45881..46318
                     /gene="ndk"
                     /locus_tag="KB969_000116"
     CDS             45881..46318
                     /gene="ndk"
                     /locus_tag="KB969_000116"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBB6868139.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(46340..47206)
                     /locus_tag="KB969_000117"
     CDS             complement(46340..47206)
                     /locus_tag="KB969_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6868140.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(47366..49459)
                     /locus_tag="KB969_000118"
     CDS             complement(47366..49459)
                     /locus_tag="KB969_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6868141.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(50208..50831)
                     /locus_tag="KB969_000119"
     CDS             complement(50208..50831)
                     /locus_tag="KB969_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868142.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(50990..52387)
                     /locus_tag="KB969_000120"
     CDS             complement(50990..52387)
                     /locus_tag="KB969_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6868143.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(52419..53390)
                     /locus_tag="KB969_000121"
     CDS             complement(52419..53390)
                     /locus_tag="KB969_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6868144.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            53764..54189
                     /locus_tag="KB969_000122"
     CDS             53764..54189
                     /locus_tag="KB969_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868145.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(54677..55378)
                     /locus_tag="KB969_000123"
     CDS             complement(54677..55378)
                     /locus_tag="KB969_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6868146.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(55394..55834)
                     /locus_tag="KB969_000124"
     CDS             complement(55394..55834)
                     /locus_tag="KB969_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6868147.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(55834..56409)
                     /locus_tag="KB969_000125"
     CDS             complement(55834..56409)
                     /locus_tag="KB969_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBB6868148.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(57257..57736)
                     /locus_tag="KB969_000126"
                     /pseudo
     CDS             complement(57257..57736)
                     /locus_tag="KB969_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(57895..58596)
                     /locus_tag="KB969_000127"
     CDS             complement(57895..58596)
                     /locus_tag="KB969_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6868149.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(58704..60113)
                     /locus_tag="KB969_000128"
     CDS             complement(58704..60113)
                     /locus_tag="KB969_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBB6868150.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(60161..62026)
                     /locus_tag="KB969_000129"
     CDS             complement(60161..62026)
                     /locus_tag="KB969_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6868151.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(62147..62997)
                     /locus_tag="KB969_000130"
                     /pseudo
     CDS             complement(62147..62997)
                     /locus_tag="KB969_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(63307..64020)
                     /locus_tag="KB969_000131"
     CDS             complement(63307..64020)
                     /locus_tag="KB969_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBB6868152.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(64088..64414)
                     /locus_tag="KB969_000132"
     CDS             complement(64088..64414)
                     /locus_tag="KB969_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBB6868153.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(64537..64764)
                     /locus_tag="KB969_000133"
     CDS             complement(64537..64764)
                     /locus_tag="KB969_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6868154.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(65086..66339)
                     /locus_tag="KB969_000134"
     CDS             complement(65086..66339)
                     /locus_tag="KB969_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6868155.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            66400..67140
                     /locus_tag="KB969_000135"
     CDS             66400..67140
                     /locus_tag="KB969_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6868156.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(67226..67984)
                     /locus_tag="KB969_000136"
     CDS             complement(67226..67984)
                     /locus_tag="KB969_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6868157.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(67981..69009)
                     /locus_tag="KB969_000137"
                     /pseudo
     CDS             complement(67981..69009)
                     /locus_tag="KB969_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(69029..72196)
                     /locus_tag="KB969_000138"
     CDS             complement(69029..72196)
                     /locus_tag="KB969_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868158.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(72420..73304)
                     /locus_tag="KB969_000139"
     CDS             complement(72420..73304)
                     /locus_tag="KB969_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6868159.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(73399..73836)
                     /locus_tag="KB969_000140"
     CDS             complement(73399..73836)
                     /locus_tag="KB969_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868160.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
BASE COUNT        21296 a        15428 c        12723 g        24401 t
ORIGIN      
        1 aaaaaaacat aaatcagcta ataaatatgt gagacaaagc tgccatccat aaatactagc
       61 tgattttttc agttaaatgt ctattttttt ctctgatgat ggtatttcca aaatattccc
      121 agtcatctgg agtcggtgga tttttccaaa ttatctgttc tttattaaat ttttcaagta
      181 aacaatcaga taaataaata ttcgtacgag aagtgattcg actctcaatc acaatattgt
      241 aatttttaaa tcctttcact tgagaaataa tgtaatcggt ataagcagat ccttgcgaaa
      301 aatcaataca gacatgaatc ggtgcttcaa aatatgatac cggacaaata ccgaccaata
      361 aaaagagata atcataaaat aagcgaatca tgaaacgttc atcttttccc aagaaatagc
      421 gtttattctc ttgtatgacc ttttggattg ctgtactgaa tattggatac gtctcgaaga
      481 aaaactgtag ctgcttttta gacgtaaagc tagtcatctc aaagtcgaat atccaatttt
      541 ttcgattgac atgcatcata cccatacgaa gttcttttcg tatatatagt ctttcttctt
      601 cagagatttc aatcgaaaat ggtaattgat caatcaattc cactgacatt ttttgactaa
      661 tcatgtggat atcatgaaaa tgagcttccg caagtccaaa tgcgccatct aattcaaatt
      721 cttcttccgt gatcaaaaac aacatgatat aagaaatctc atcaatgatc tgctctttag
      781 ggatatgaag aaaagaaata tgtgataaat ccttgatgat cttcattcct tctgagctct
      841 taaagtattc atctgaaaag aaacgttttc cgattggttg attcccatag gccctcaaca
      901 aactaatagt ggttagcaaa ttgaatttga ttcgttttgt tgcagacagt tttaaattga
      961 acagatattc aaaatattgc acgatactct ttgcttcatt catgacgctt tctctaaatg
     1021 gcatagaaaa accattaaag accccgaaat ataccccaaa taatacgttc cgtatgttta
     1081 tttcttcccc aactaatatg tttttcttta actttatttg atgctgttca agaaaagaga
     1141 ctaattctct tctttttaca taggctcttg atatgcttaa aaaatgattc tctgcaaatt
     1201 tttcgatcgt tacttttgaa tccacgatct ccgttaacag tcgagcaatt tttgatcgtt
     1261 gaaagtagat tcttcttaaa tttttgatat ccgtcaaatt cagacgttcg acatggatct
     1321 ctgcttcttc tgaaatttgg atctctggct ttgttttgaa ttcagtaaat tctttattta
     1381 attctatgat ataatttctt gttttaaatt tagacaaacc taatgtttca tataacttag
     1441 gcagcactac ataattcttt ttctcaaatt ctaaatatct agctagcagc agtttttctc
     1501 tatcttcctc ttctataagg taatccaact tcatatccta cacctcaaaa aatgcctcat
     1561 accaattact tgatatgcag atgaaagttc atcttttcac ctatactgat tttatgatgg
     1621 attatgcttg ttttttcatc agttattctc attttttatc ttttttttga gaatattgca
     1681 aaaaatggaa aaatttatga ggaaatattc tatatttttt gttttattgt gttaaaatgt
     1741 acaagatttg cgccatttgc gtaaacaacc acaaaaaaga gcaggacggc caccgtcctg
     1801 ctcttttact tattttaagt tccattactt attaattggc taaacttctg cttgtttctg
     1861 atattgcttg tttttctcca atgatccgca cttctgtttc taaagacaca tcaaattttt
     1921 ctttgattac ttcttggatg tgcgcaatca attcaatata atctgtcgct gtcgcatgat
     1981 cgatattgac gatgaatcca gcatgttttt cagagacttg tgcaccgccc catttcaggc
     2041 cttgcaatcc tgcttgttgg atcagctgac ctgtatagtg tcctactggg cgcttaaaga
     2101 cacttccgca tgaagggtat tctaatggct gttttgattg acgcaattcg gtcaactcat
     2161 ccattcttgc tttgattgct tcataatccc ctgtttgcaa actgaatcga gcttccaata
     2221 cgatagcacg taattcttgg actttactgt gacgataaga aaataccatt tcgtcttttg
     2281 tcaaagtttt caatgttcca tcttcaagca aaagatccac ttcagcaaaa acatctttga
     2341 tctctccgcc atacgcacct gcattcatat aaaccgctcc accgacactt cccgggatgc
     2401 cgcaagcaaa ttcaaatcca gtcaatgatt ctgccaaagc tgcataagtc gtatcaatca
     2461 gtgaggcacc tgcttccgca atgaccatcg ttcctttgac atgaatctgt ttcatttcag
     2521 tcagcatgat gactacaccg cgaatcccgc catcttgaac gatcagattg cttgcatttc
     2581 ctaataccat ccaaggtata tcatggattc ggcaataatc gatgatttgc tttacttctt
     2641 cttgtttttt cgggaatgca aggacatcag ctggtccacc tgttttcgta aacgtatagt
     2701 tcatcaatgg ttcatcaaac aatatagtaa tcgtggctaa gctttcaact atttcttctt
     2761 tattcactga ggattttcct ttcttttctc aaacgtcctc attattctat cacgcttaat
     2821 acaatcttgc cagtcttgtt caaagttgat gacggtagtg atctttaagc acttcctcac
     2881 ataattcatg acttcttaca acttcttttt gtttaagcaa ttctgtttcc gatttaccta
     2941 aacggatctg agaaaagaag gcctctacca ttggctcaaa cccgcgtttg actagcgtgt
     3001 ttgtccagtc gccaaattct ttcacttttt ttccatcagc atcttgaatg acaagctggg
     3061 tcagatcgtt tacttcataa gtaccatttt tacttgttac ttgatatttt tctatattag
     3121 cgccacttgc taaatccatc gttaaaatag ccgtttgatt ttgtgtttct aattgtaaaa
     3181 tggcatattc caaaaattcc tttgtttctc ttatctggta ttttgttctc aaaatgggtt
     3241 catctaataa atacacagct gtatcaataa gatgtaaaaa caaatcataa aggacgaact
     3301 ctgtcgtttc ttttgccgct attcgatttt tttgcaggtg gatcaaccgc ttatctggga
     3361 tacgtttcaa ttcttctacc ataggagcaa agcgccggtt gaaaccgatc atcaaaatta
     3421 tttggttctt atcagctaat tcttgcaatt cacgaacttc atttagatgg acactcagtg
     3481 gtttgtcaat ataaacatgg ataccatttt ctagacattt tttggctaat tcataatgta
     3541 cttttgttgc tgcgtggatc atacatgctt cgattttttc ttctaaaagc tcatcgatcg
     3601 tttcatatag atgttggaac ccgtactctt tttgaattct ttcttttgtt tctttatttc
     3661 ttgttgcaaa ataaaaatca agtgttcctt gttttttcgc ataagttggt aaatatgctt
     3721 tttctgcgat attccctaca ccgattacac caatcttcat ctactttcct cctggatcat
     3781 ttagttactt tcatcttaca ccattttttt ctaaaatgag gtacaatagt atcgcaaagg
     3841 taaggaaatt aattcgaagg agtgtgcttt tattgaaatt tatctcttgg aacgtaaacg
     3901 ggcttcgtgc catcgtaaat aaaaattttt tagaagtttt tcatgagtta gacgccgatt
     3961 ttttctgtct gcaggaaacg aaactccaag caggacaaat tgatttagat cttccaggtt
     4021 attatcaata ttggaattac gcggaacgaa aaggctattc cggcacagcg atttttgcta
     4081 aaaaaccagc attgaatgcc acttacggaa tgggtatcga tatccatgat acagaaggcc
     4141 gtctgattac tttggaatat tccgatttct ttcttgtaac ctgttacacg ccaaattctc
     4201 aaagcgaatt aaaacgttta gattaccgat tagaatggga agaagccttt tataattatt
     4261 tggaaaatct aaaaaaacaa aaaccagtca tcgtgtgtgg ggatctaaat gtcgctcatc
     4321 aaaagattga tttgaaaaac tggaaaacga atcaaaaaaa tgctggattc actccagaag
     4381 aaagagcggc tctttctcga ctgttggata acgggtttat cgatacattc cgttattttt
     4441 atccaaccca ggaaggtgtc tactcttggt ggaactaccg attcaattca aggaaaaaca
     4501 atgctggttg gcggatcgat tactttttga cgagcaaaga tttagagcca ggactagctg
     4561 atgcaaagat ccatacggac attatgggca gtgatcattg tccagtagaa ttagatttga
     4621 aataaagagg ttgtgaaaaa gtcgtttagt ttcgagtatt aagaaaaatt ttgtgaaaat
     4681 ggctttccac attttgcata aatttggcat aataccgaga aactggcttt tgaacactgt
     4741 ttatcgagag attgtgaaaa agctgtcctg catcaagtaa taagaacagc caaacaaaaa
     4801 tagttcctca tatttttcgt ttggttgggc ttattaccgc agatacaagc ttttgaacac
     4861 cgtttattaa gaggttgtga aaaagctgca ctgcatcaag taataagaac agccaaacaa
     4921 aaatagttcc tcatattttt cgtttggttg ggcttattac cgcagatgca agcttttgaa
     4981 caccgtttat taagaggttg tgaaaaagct gcactgcatc aagtaataag aacagccaaa
     5041 caaaaatagt tcctcatatt tttcgtttgg ttggacttat taccgcagat gcaagctttt
     5101 gaacaccgtt tattgagaag ttgtgaaatc agcgtcctga cctgagtatt agagaaacaa
     5161 atggcaaaat agttcctcat attttgctat tttttgagct aataccgagg gtcagctgat
     5221 tgaacaccgt ttagtggaga agttgtgaaa aagtcgccta ctttcgagtc gtaagaaatt
     5281 tttttgaaaa tggttcctca caactttgca taaatttgac ttaataccga gaagtcatga
     5341 tccccatcta actccaaatc acaaggaatg agttcaaaaa ctagcttttc tcaacaaata
     5401 ttacataaaa aattctatgt tttttgttaa atttatttgc ttttttcaaa agtatgttac
     5461 agtaatttcc caaggaggtt ttacagaaat gaattttgtt gccatggatt ttgaaactgc
     5521 caatcatcag ccttatagtg cttgttctct tgcgctagtc atggtaaaaa atagccagat
     5581 cgttgatgaa ttctatacat tgatacagcc tgagactcct tttttctggc gaaatgtcca
     5641 aattcacgga atccatcaag aagacgtacg caatgcgccg aaattcccag aagtctggca
     5701 aactatccaa ccatattttc aaaaaaatcg tttagtcgtt gcacataatg ctgcttttga
     5761 tacaaaggtc ttagcgggat gcttagatta ttatcatctt gaacagccta attatctttc
     5821 tttatgtaca gtgaaaagta gccgtcgcct gtttcctgaa tttccaaatc atcgattgaa
     5881 cactgtgtgc gaaaatttga acatccaatt agatcatcac catgatgcat tggaagatag
     5941 tcgtgcatgt gcggaaatcc tgctttatca agaaaaaaaa ttcgggacag atccattgaa
     6001 aaaacttgtg actataaagt aaaagaatac ttatgaaaca cacaaagagg tcgtgagcct
     6061 gccgtttcac tccgagtcac aaggagcaat ttcaaaaaat agcttctcat gtttattaaa
     6121 tattgtgact ggtgaccgag gagctggcag gagaacaccg tttattggag aggttgtgaa
     6181 aaagctgttc tgcatcaagt aataagaaca gccaaacaaa aatagcttct catatttttc
     6241 atttggttgg acttattacc gcagatgcaa gcttttggac accgtttacc aagaggttgt
     6301 gaaatcagcg ttttgacctg agtattagag aaacaaacgg caaaatagtt cctcatattt
     6361 tgccgttttt tgagctaata ccgaaggtca gctgattgaa caccgtttat tcaaaaaaaa
     6421 tggactgcga cacgactttt gtcacagtcc cttcgtgtgt ttttctgcct tctcaaaagg
     6481 atgacagttt ctcactcttt tcctatttct tctattcaat caaataactc attttatata
     6541 catctaaaaa ttcacctaga tctgttcttg cccctctagg catgaccgct tcgatttgga
     6601 agcccatttt tcggtaaagg tgtacggctc tttcattacg aacttgaacg tcaagctcca
     6661 atcgaaaaag tacacccatt tccttcgccc aactgatgat ttcttctagc ataagagtgc
     6721 ctagtcccat tccccaatat tcctgcagaa tactgatacc gacttctccc acgtgagaca
     6781 aacgaaattg actgtctgcc ttgacagatg ctgttccaat aatcgtccct tcatagattg
     6841 caagcagcaa taaattatta ttgctttcgt atatataatc caactcttct tctaaggttt
     6901 ctggtggtaa caggagttct gcttcatcca aaactaaaaa ttctgtctcc ttattaactt
     6961 gtcccatcat caaaagaatg tcttttgcat ctcctggcac tgcttcccgc aagatgatcc
     7021 caacttcttc actcatgatt ttcagcccat ttttctagaa ttcgctgttt gaaggtttca
     7081 ctttgctccc cgtatgagat tagtttcaca taccgctttt ctaaatctgt atcacttttt
     7141 tctaaaatca gttccaaata atcctccggc agtgcttctt ctaatagatt tccccattca
     7201 acaacggaaa gcccatcacc ttcaaaatat tcatctaacc ctaaatctgc tccgctagct
     7261 gctacccgat aaatatccat atgatacaac ggaatccgac cttgactata ttctctaata
     7321 atcgtgtatg tcggactttt gatcatttgc gttatcccta atccttgggc aattcctttc
     7381 gtcaacgttg ttttacccgc acctagatca ccagtcaata tcagattgtc acctggcatt
     7441 gcggaatgac caattgcctc tgcgaattgt tctgtcattg ttaatcctga tagttcgatc
     7501 atttttcatc ttctcccgct cttctttctt tttgccagta tatcgcgtaa tgaagttttt
     7561 ttaaagaaaa aatgaactag tcaagaacag cagctgctgt ttttggctag ttcgcgtgta
     7621 tttgttaatc aatcaatgtt tgtgctgctg tgataatcga taatttatat acatcttctt
     7681 catttgctcc acgagacaaa tcagaaaccg gtttgttcaa gccttgtaga attggtccga
     7741 ttgcttcaaa gttaccgaaa cgctgagcaa ttttatagcc gatatttcct gactgcaatt
     7801 ctggaaatac aaagactgtt gcttgaccag ctacttctga atctggcgct ttcagttgtg
     7861 caactgaagg aacataagaa gcatcaaatt gcaattcgcc gtcgatcatg tattgtggcg
     7921 ctagtttttt agcgatttta gttgcttcaa ctactttgtc tacttctggc gatttcgctg
     7981 agccttttgt cgagaagctc atcattgcta cttttggttc gatatcgaac aattctgctg
     8041 tttttgcaga atctacggcg atttcagcca attcttgcgc agttggattc acgttgatcg
     8101 cacaatccga aaagacatat ttttcttgat ctcttccacg taccatgatc atcgctccgc
     8161 ttgtccgact gatgccaggc tttgttttga tgatctgaag tgctgggcga acagtgtcgc
     8221 cagtcgaatg gatcgctcca gagaccattc cgtctgcaat ccccatatac gtaagcatcg
     8281 taccaaagta attcacatct tttaaaatct tttctgcttg ttctttggat gcctttccat
     8341 ttctacgttc aacaaaagta tccaccattt catcccactt atcgtaatta tcagggctga
     8401 tgatcgtaaa gctagatgtt ttgattcctc tggcatgcgc tgcatttctt atttcttctt
     8461 cgttccctac taaaatgggt tccacaagtt cttctgcttt caaccgggca gctgcgccta
     8521 aaatacgagc atcagtagct tccgggaaaa cgattttgat cccacggcga acaattttaa
     8581 atcttaaact atcaaacaat tccacaagat gacctccaga cgtttttata tgtattatca
     8641 tacactattc cagaaaaaaa taacagttta ttttatctgt atcagtcaaa aatgctggaa
     8701 aaattaagtt tttcacatac aaagcgaact gcactataac aggaaagcgc tgttttatta
     8761 cactgtttca ggcagttgcc aatcaatcgg ttcttctcct aacgcaagga gcgcatcatt
     8821 cgttttcgag aagggtttgg aaccaaaaaa gccacgactt gcagataacg gactgggatg
     8881 tggagatgtt atgatgatat ggcgactctt atcgatcatt ttgatttttt cttgtgccgg
     8941 ttttccccac aagataaaca cgattggttt ttcccgttca tttaattttt caatgatcgt
     9001 gtctgttaat ctttcccaac ctttcccgcg atgagaatac gcttgccctt cccgaacggt
     9061 aagaacggtg ttgagtaaaa ggactccctg tttagcccat gacactagat ttccatgttg
     9121 aacaggtgcg attccaagat catcataaag ctctttatag atatttctta acgatggcgg
     9181 gatctttacg ccaggttgca cagaaaaaga taagccatga gcttgatttt ctccatgata
     9241 aggatcttgt cctaaaatca ccactttaac ttcttcataa ggagtcaatt ccaatgcttc
     9301 atagatatga tacatatctg gatggatctt ttgggacgca tattcttttt ttaaaaattc
     9361 tcttagatgc agataataat cttttgaaaa ttctgaggac aaaacttctt gccaactgtt
     9421 atgaatgatt tctttcaaaa actccacctc ctaataaaaa gaataactca cattttcttc
     9481 aatcacaagg gacaatcttc accctcagca cttgattaat atggtaaact aggaacaaga
     9541 agcagaaagg aacgataatc attatgatca aattaattgc atcagatatg gacggcacat
     9601 tattagatgc ccatatgagt gtttctcctg aaaatgccga ggcgatacgt tttgcaaatg
     9661 atgccggtgt tgagttcatg gtcgctactg gtcgaaacta tcaagaagct cgcgcagctt
     9721 tagatgaggt aggaatcgat tgtgcgatga tcactttgaa cggggcacag gtatttgata
     9781 aagaaggaaa ttcattgttt accgtgtcga ttccaaataa tcaagcaatc tctgttttag
     9841 atattctaga tgctaacggt atttactatg aagtagcaac caacgatggt ctttattctg
     9901 aaaatcaagc gaaacgaatt gaaagttttg cttccatggt ggctacccat ttacctcacc
     9961 ttacgtataa aatggcgatt gccatggcct cagctaagct ggagttattg cacatcacat
    10021 acgtggacag tattcgtgct attttggaag aaaagaatct ggaagtttta aaaattattt
    10081 gttttcatac agaagggcca gctgtattag gtccagttgg aaagcagatt tctcttttag
    10141 gcgatctagc cgttacttcc tctggtcaaa acaatatcga agtgaaccat aaaaacgctc
    10201 aaaaaggaat tgctgttgcc catgtcgctc acgagcgtgg gatttcttta gaagaagtca
    10261 tgacgattgg cgataacttc aatgatgtca gcatgctgca agtagcagga gtcagtttcg
    10321 caatgggaaa tgcagaaatc gaagtaaaag attatgccaa atatacaacg gacacaaacc
    10381 ttgaatctgg cgtaggaaaa gccatattgc gcgcgattgc agaagacttg tagttttatc
    10441 tagaaaagag ggatatagat gtcagaattt ttcattcagg aaaagcagct tggacgtgca
    10501 actcggacaa ttgtcaaaaa cgaaaaagga cattccctgt ttttgatggt tggtcgctgg
    10561 ggaacaaagg gcgatgcatt gtctctttat gccatgaatg gcgatctcgt tgctcacatc
    10621 aagcagataa gcctgacatt cggtacgcgt tttgagctgt ataaagagtt cgaaaaggtg
    10681 ggaaccatgc agaaaatatt caattggccc ggtgactttt attatattcg tagacttcac
    10741 tggacagtcc aaggtgatat ctataatcat caatatcaaa tccatcattt caatcagcaa
    10801 atcatgaaaa tggataaagc aacacttttt tcaggagatt actatgtatt ggatgtctca
    10861 aatgatgaag atgctccagt ttgtatttgt attgctgcgg ttttagatta ctggctctac
    10921 cgtaaagaca aaagtcgcga taagcctgtt tcttaccgac ttaacttaag ttaaaaagat
    10981 gtacctgaaa tgcggaaata cgcatttcag gtacatcttt ttagatattc ttttgcatat
    11041 gatcataaag atgaccactg atcatccgct gaccgacaac tttgaagtca tggcgttcgt
    11101 ataatttttt agcctttgga tttttttcat ccacacttag accgatgacg gagcgattag
    11161 ctttcttcgc caatttaggt aatgcttcta ataatcgcga accgatgcct tgtcctctaa
    11221 aatcttctga tacactgata gagtccaaat accattcgtt gggaaacgtt tctttatcaa
    11281 tgaacaaacg tgtagacgca tctagctgat atttctctaa gataggtacc agtggctgat
    11341 cgatgattga ttcttcttca tctgtataac cgtaagcaac tcctgcaact ttaccgtcta
    11401 tttcttctac gatacctcgt gaataactgt aacgataatt tggatcagtg attgcttctt
    11461 ctaaaatctc taaagtcttt tgttcccctg tctgcttcaa aaatggcagt tccatatctt
    11521 ttagaatcac taagatcaat ggggcgattt ctggagcatc ttcttttctc gcaaaacgaa
    11581 tcatagtttc ctctcctttt ctccattcta acatgcagaa aaagaaatcg caaaatcgtt
    11641 attttaaaaa atcttcaatc ttttcagtaa tgaaataacc atgagtaacg attcttgccg
    11701 cttcagttcg gcaataaggg cagacgactg gcatttcttt atcattatgt tcgactacat
    11761 tattgacttc ttcgtatgca aatttttttc cgcaattagg gcatttcatt ttttccatgt
    11821 tatctcaact tcctttcatc tttactctct tagcttactc ttatattgta aaaaagagaa
    11881 gcaatatcct tcttctatgc agatatccat acctgacggt cctgttctcc atctattaat
    11941 cggactttat aataaggacg ttcatctttg actagaagtg tccactcttt cacttttgct
    12001 tttttcccgt agtagctgac tgcttccttc atcgctgctt gcggttgttt gaactcttcc
    12061 gttttttcta tatcaaaaag atgttctgcg gccttttccg tgtcatttcg tacggttgtt
    12121 ttcccagtgg atggattgac tgctatgact tgtccttcac aaaaaaactg gtattcatat
    12181 gttgcattcg taggattctc caaatctttt tcaactgcaa aatgaatagc agatatgtta
    12241 tgttcttttg tttcgttttt tacgattgct gctgcttttt tcaatgagat ccgatattcc
    12301 tggtcactaa tatcatccat gtgaaaagcg gcattgagca gtcccgtcat accggtaatc
    12361 cctattacga tgagggcagc aacaccaaac atcatttttt tcattcttca ttctcctgtt
    12421 tctttttttt aaagaatatc aagaaatgaa cgaatgaaaa atcgaatgaa acgaaaaaaa
    12481 agtgacaatt ttgttatctt tattcgtgca gttctaatgg caatccgtct ggatcaaaga
    12541 aaaacgtcat tttttttcct gtaaaggtat cttctctaat cggttctgat tcgatcccta
    12601 aggactgcaa ttctgcaatt gtttcttcaa tatcgtctac tttgaaagca agatgacgca
    12661 agccacaagc ttctggatag tttggtcgtt gtggcgcatt agcaattcca aaaatctcca
    12721 attcagcact tcctagtttc agatctaatt tatagtcatc tcgttctttg cggtaatttt
    12781 ctctgattac ttcaaatcct aatttattaa cataaaaatc acgtgatttc tgataatctg
    12841 aaacaatgat ggctatatga tggatcgttg taaggttcat atgagcactc ctattcttcg
    12901 tttaagctcg gatctatatt aatctccagt tccattgtaa atgtgtcaga ttgaaaaaaa
    12961 tagctgtttt tcctttttat aagaaaaaag gcaaaaaaaa cagaaagtag gtcctccaag
    13021 acactcttcc tgttcccaat ataataaatg aaagtaagaa attatatttt caagaaaaca
    13081 aacagaaaat tatcataaca caaattattt ataattgaaa gactagtttt ttttcaagaa
    13141 aagcatacaa tagattgtgt tagtaaatac agaacacact acatttagtg tcttaaggag
    13201 tcctcataca tgaagtcata ttttcagttt ttagctcatc agctaaaagg ctggccgcaa
    13261 caaaattatt atcttttctt tttcagtctt ggctgccagg tcatgactct tgtcaatagt
    13321 cccatcactt ggctgtccgt tattacattt atcggtacca cgcttggtgt attgtgtatt
    13381 ttatccatca atgcggcaaa atcagtcaac ggtattttag gtattttgtc tgcgatttgt
    13441 tttattatcg ttgggttttc agcaaagaac tatttaagta tcggtgaaca gattgcttat
    13501 atgatcacat tggatatccc cgtattgtta agtaaagaat ggaatcataa tatggcttca
    13561 aaaatccgaa aattcactgg aaaaagctgg tttatcgcaa tcatcagtac tttccttgtc
    13621 tatcttgttt caggattcct gattggtcgt tatacagatg atcctcggcc gtgggtagat
    13681 gccattgctt tttctattag cttgactgct ggtatcatca gtttcttgcg ttacaacaac
    13741 caatattact ggtggttagc ttcagggctt gctcaaatgg tcctttggta tatttcattt
    13801 acgcatggat ctgcaagttt ggcgatgttc gtgaacagct ctgtttactt gctgaatgat
    13861 gtccttgcat ttaccgtttc accttggtat aaccaaaaag aacgtgaacg tatgcaaaaa
    13921 atggaagaag aatactacaa cgcacaacaa cacgcataaa aaaactgagc gtgggacaaa
    13981 agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaat cagaagcaac
    14041 tccttcggaa ataagctgaa attcacaaaa atttgaaaag caattttcgt gaatttcttc
    14101 ttatttcttg gagttaaacg cttctgtccc agcctctatt ttttatagta attccttcag
    14161 atactttctt gcctcatcat tgaaacgcag tgattcttct aacttctgat aatattccaa
    14221 cgcttgtttc tgagcttcag taaaacgata atgttttcct ttccatttgt cgattgtctc
    14281 ttgcacattt ccagattgga tatctttcac tactagttgc catttttctt ttgagactgt
    14341 acggtctttc ttatcagcag attgtatagc ttctcgttct ttacgcaata cttttaaaaa
    14401 accatttctg actatccgag gaatgctgtc gaagaaccct tctgtaaaac catagcgaca
    14461 atattgcttc caaataaata gatagatttt tggttggatg aatcgttggt ttttcgcaaa
    14521 atattccatc tgagcagtga cttctggtgt tcgttgacgt tttgtctttc tcaacacgga
    14581 aataaatgtt tcaaaataag cattaggatg tactggcact tcttcatata cgatggattg
    14641 ccaatcttta cgtaaaaatg cgcgatagtt gatcaagaat tcttctacat cctttactaa
    14701 ttcttctgca aagtcgtcaa atagttcttt ttttatctgt cgcttttttg actgcccatt
    14761 gatgtgttca cttattttct tgatttcatt ttccaatgct tgataatccg ctatgtaaat
    14821 cggcatttct acttggcgaa attctgcgag ccgctgagct aattttatat ccggtaaata
    14881 tggctgtttc atccgacgat tttggtacaa gacaaaacag tatttttgcc atagtccttc
    14941 aggaaaatcg atattcttct gcttaagcca taataattcg tctaaggcca gatcaacttt
    15001 tgtcattccc tgatggatcg aagctgccac tgtcggagag acatgcaggt gatcggcaaa
    15061 gtggttgatg cctagtttta ggatctttcc ggtttttggc gatttaacga tgtattgcac
    15121 ttttaattct ctaccacact cacaatacaa tttttgctgg cttcgttttg ttcgaaaaaa
    15181 cggattgatc ttgaagtcag aaaacaccca atctgttgca gctaaataat gttcttccat
    15241 aaaacgagag ctgattagat atcggcggtg cttatcgact agttcccgct gttttttcgt
    15301 taattttgca tagatctccc aacgttgact gcttgtgtat tgtttagaaa ttttgatggg
    15361 atagcttttg ctgatttctt ttggaaacca ttcttcaaag acggattgcc attcttccac
    15421 ggctgtttct ttcctttcta attacaaaaa gctggctact aacataacgt tagcaaccag
    15481 ccagtgtttc ttgctaaatt agtgagttgt tccggcattt ccggaaatat cttctttatt
    15541 ttctactgct gcttcaactg cataagtcaa agaagaagca atgtcttcta aagacataga
    15601 aggcgtaccc actggacgat cgatcacttg atcgggtgag aatggcacgt ggatgaaccc
    15661 acctcgaatt gccgggaatt gtgtttcgat caaatgaagc aaacgataca tgatatcatt
    15721 gcagacaaat gttcctgctg tataagagat gtacgctggt agaccatgat cttgtacatt
    15781 ttttgtcatt gctttgattg gcaatgaggt aaagtaagcg gctggaccgt tttcttctaa
    15841 agccgtatcg aatggctgat ttccttcatt atcagggatt cttgcttctg ctagattgat
    15901 tgcgacacgt tcgaacgaga ctgctgaccg cccacctgct tgtccgacac agatcacgac
    15961 atctggttgg tgctgttgga tggcttcttt gactacttga ctgctttttt cgaatacggt
    16021 cggtacttcc actttgatga tttcagcacc gctgatttca tctggcattt tttttactgc
    16081 ttcataggct ggattcactt tgtccccacc aaatggatca aaacctgtta ctagtacttt
    16141 catctgttgt tcctccgtcc gattgattta acatatggtt atcttttatc ataccatttt
    16201 ccttgaacag cgtaaataaa ggaaacaata gtttaaataa cataacagat caaacttaat
    16261 atattcttat aaaaaaatag tgttccacta caatgttaga agaggttgcg acaattattc
    16321 tgtcacaacc cctctcttct attatttaaa tagaatcata taagcaattt ggaaaactag
    16381 cataaataac gcaataaaca actggttttt gatcactccg tatttgtctt tcatctccag
    16441 catcgctaca ggcacgatat tgaagttagc agccatcggt gtcagcaggg tcccacaaaa
    16501 accgcaagtc aatgcaacca ttcctattaa cgctggattc gctccatgac taaatacgaa
    16561 tggtgcaccg atcccaaccg tcatcacggt gatggccgca aatgcattcc ccatgattac
    16621 cgtaaatatc accatgccaa gagcgtaaat gatgatgccg atgttcacat ttccttctgg
    16681 aacgatcgta cctactgcat tggaaatcac tgtcccaact ccagcgcttg taaataccgc
    16741 acctagagaa gctaaaagca ttggcaacat gcttaacggc cctactgtgc ccagcatatc
    16801 tgctgcatca tctaaaaatg tacttggtcg attatctcga gaaaagaaca tcaagattag
    16861 catggctgca aaaacaccga cgcccacgcc gactaaagca cctaaattgg taaatagagc
    16921 aaacaagatc gcaaagacac cgatactcaa agctggaata aaaattttca ttcctagttt
    16981 gtctgacatt ttttccatat attcttttga tggaagccgg ctttctcctt tgctgacttt
    17041 cttagcaatt gctggtatgg tcatcgcaaa gatcaagcca ccgttcacga ttgccggaag
    17101 ccatcttcct cctgcaataa ctacccctaa gaccgtccag aaaaaggctg acccataacg
    17161 atgaggattg gttttatctg ttaaatttct tactccagtg taaatcaata cgagtcccat
    17221 cacgatataa aggatctcca gtaatttatc gcctaataaa atatcaggat ttgtaaaaaa
    17281 gtccatctta ttgccccttt cctggataat atttcttcgc taatttcttt tctttaagat
    17341 agaagtagac acttgccaca actaaagccg tgatagccac tggaacttcc actaaagcaa
    17401 gctgtcccaa tgttacgtca tatcctagat ctttcagtgt tgattggact agcaacgccc
    17461 ctgctcctcc gatgaatagt acttggccaa agaaccagca gacattttcc atagctgaag
    17521 ccataccttt tagttcttct tcatgcttag gatggacttc taaccctttt gattcgatgg
    17581 tccccaatgc catcggtaaa atgattggac gaacaaatcc agcaactcca ccaaaactca
    17641 cgttaaaagc cgcaaagatc attcgaaaga tcccataaat atctacaatc ataccagcag
    17701 atactttctt gaatcgcttg atcaaggaag ccgctgattc tttcagacca tttctttcaa
    17761 gcgttcctgt tgccaacata atgatgataa aaatcgccat cccgcgattg tttacaaaac
    17821 ttgtacctaa aagttctaac attccttgaa tgccaagacc gccagtcaaa gctgtaacaa
    17881 ctaaagcaac cattacgatc aatatcgagt ctaatttaaa tgcaaacccg agaataacaa
    17941 tcaagacgcc taaaaggcta agataatttt ccatatattt tcctccataa aatgacaata
    18001 tttttttaat tataaagcaa aacacataaa aaatatagtt gttttctcac gaaatagaca
    18061 ctatttttaa atatttttcg ttattttttt atcacaaaaa ttatcttact tattgtaagg
    18121 taaagctttt tttaatttat tgcccgataa tatatagaaa taaggtctag ttactgtttt
    18181 ttttaaatga ttaataaata acaacttctt tctatgaaat tgcaaagcat tcatcttctt
    18241 ttccgctaac gatatatccg tcagtgcttg gtacacttta ctaaaaagta tgagattgcc
    18301 gatatctgga taggtgtgct atactacaga aaaagatata caatctgcca ccgggtagga
    18361 taaagaggat gatcattcca ttaggtcttt gaagggatga ttttcctctt tttgtgtatt
    18421 tttttatagt taaggaggaa tgtaagtatg gcatggatgg aattaatcat agcaggaatt
    18481 ttggaagtat tctggtcaac gatgatgaaa tggagtgatg gtttttctaa aatcaattat
    18541 tctttttaca cagtgattgg catgattgct agtttttact ttttgtcaaa ggcaatcaaa
    18601 agtttgccga tgagtctctc ttatcctatc tggacaggga ttggcgcagt tggttcggtc
    18661 ataattggtg tggtcttgtt tcatgataag ctgaatcttt ccacttggtt ctttgtgggg
    18721 atgctactca tcagtatcat tggcatcaag attactagcg gccactagac acttggaata
    18781 agtactgatc agaaaaaata agccttttta tttaatattc aattttttta tgaaaaaata
    18841 agaaataagt ccaatgacct agcgacttct ccactcatca ggtgtatgct tgtactatct
    18901 atagaaaagg agtgaatatt tttgaaaagt ctttcggtcc aagaattatc caagaacttt
    18961 ggtcacaaac aagccctcag cgatgtcagt tttagcttat cccctggcaa aatcgttgga
    19021 ttagtaggtc ctaatggcgc tggaaaaaca acgatcatga aagctatttt aggactgatc
    19081 cattactcag atggaacaat ctgtattggt gaaaatgaga tttctccctc tagtcataaa
    19141 gggttggaac aagtaggagc attgatcgaa tacccgggta tctatccatt cttaacaggc
    19201 tatgatcatc tgaagttatt ctctgaaacc aacgatgtat ctgctatcga cactatcgtg
    19261 aatcagctca agatggaaaa gtacattcac aaaaaagcga aatcctactc gttgggaatg
    19321 aaacaaaaat tgggaattgc tcttgcctta ctgaaccatc cgtctatcgt tattttagat
    19381 gagccgatga acggtttgga tccacaagca acaagagatg tgcgaaaaat cattaccgac
    19441 ttggctactc agggcacctc tttcttgatc tccagtcact tactcagcga gcttgaaaaa
    19501 atggtcgatg agctgatcct gatcaatcaa ggaaagatca tcaaacaatg tacaatggct
    19561 gaattgaacc aaacagcgca agatttcatc gttatctcta caacaaatga tctagctgct
    19621 cgaacgatct tgacagaagc tggatatact ttggaagatc ctgataaaat caagctttta
    19681 aaagaaaacg aagaattatt aggaaccgtg atccagctat tgtctgcaca aaatatccat
    19741 gtgacagacg tccagcatct gacgaatgat ttggaatctt ctctattgga aattctggat
    19801 tcagtaaagg gggaagaaga aaaatgacat tgcttgtaaa acaagaatta tttaaattga
    19861 tcaagaaaaa gtcaactgct gttttatctg ttctattagt tgttttgctc ataggaacag
    19921 cacttctagc caaaaaatac acgacgatca ttgatccagt tgaaatgact gctcagcttt
    19981 ttagtgccac atcttggatt gtctttatca tgattgcagc tgcaagcacg atcatttcga
    20041 tggaagcaca atatggtaca ttgaaaaatc tcctttatcg aaagtattct cgaggagaaa
    20101 tattagtaag caaatggatc acattagtta tttattctgt ttatttatac cttttagcta
    20161 ttattgtcac tgtgttgatg aaactgattc ttttcccttc gatttccttc acggagaagg
    20221 tttctactgg tcaaacactg atccaaagct tgttcactta tactttgggt agttatatcg
    20281 gtttatggct gattttaagt ttagtgttga tgattgcttg ctttatcaat agttccggcg
    20341 catccatctc agcaggaatc gtcttttatt ttgcttcgtc aatcatatct ggtatcctta
    20401 ttgcactcat ccaaaaatgg gagtggatca aatggaatcc gatcagtatg ttgaatctgc
    20461 aaaaccaaat tggaaacgaa gagatcatga agcaattgac tcatctttct actaatcaaa
    20521 tgctattcgg taatttagct tacatcgttt tgttcttagc attaggatat ctcgtattta
    20581 agcgaaaaaa tgtatgatga ctcatcaaaa aagaggctgt gaaagagacg ttcagcctta
    20641 ttgccgattg gctgtctctt aaacaccgtt tattctgaaa aaggagctgt gacaacattt
    20701 gtgtcacagc tcctttccta gtatgttttt gaataaacga caggctcaca acctctcttt
    20761 atacttcttt tatacttcta tacgtgaagc atcccagtgg caaataaaac cattgcaatc
    20821 actccgacca tcgtcacacc tataagtaaa atcttatcta agtggatatg ttgtacaggc
    20881 tcgttttgct ccttacgtgc tttgaggtaa aaataaatgc ctggcaagaa aagaacaaga
    20941 acaagcatta cttcattaaa ggctacgact agcatagccc atacttgaaa ggcacttgct
    21001 aaaagcccta ctaaaaattg gacccattct ttccgctgat aagaaagttt catttggtac
    21061 aatcctaaga aaagccacgt gaagaaaata gctgctgtac caagtgtgta agcaaagtta
    21121 taagcactgt cagtgaataa taatgaaagt aaaaagacat tcgtacataa cgtcgtcaat
    21181 acgatagcat aagttggtgc cccatttttg ttgagttttc cccatgcttt aggcaaaagt
    21241 ccgtcttcag ccatgtttcc cattgtttca atcggtaaga tcgtccatga gagccaaaca
    21301 ccaactaaag aaatgatcaa accgccgttg atcacgactg ctccccattt accaaccatc
    21361 atttcaaaca catagcccat agcaggctgc gccttgatcg tttgcagctg attcatcgtc
    21421 attgtcccat atggaagcat ggaaaccaag acgtaaataa taatcaagcc gaatatccct
    21481 agaatcgttg ctttcccaac atctgattgt ttttttgctc gtgaacctac gacagaggct
    21541 ccttcaatac caacaaatac ccaaagcatc accatgatgc aactcaatac ttgactggaa
    21601 aacgggatcg gctgtccatt cgcattcaat ataatgtcgc tagaaaagtt atcaatgaat
    21661 tgttggatcg aaaacgtgct gatagctact acaataaata aaaataatgg cactaattta
    21721 cagaatgtga cgatagcatt gacgaaacta gcattttcga ctccccgatt cactagccat
    21781 gcatatcccc ataaaaagac tgtactcatc acgatcgatg ccagattttg cccaccttca
    21841 aatactggga agaaatatcc taatgcgctc atcaacaatg ttgcaaaagc tacgttgcct
    21901 aaccagcatg tgagccagta accccaaccg ctgataaaac cagcgaaacg gccaaaacct
    21961 tcttctgcgt aactaaagat cccgcctttt aaatctggac gttttttatt gatattattg
    22021 atcgacaagg agagcatcaa cattgctgtt cctacgagta cccaactgaa aatagctggg
    22081 ccgccagccg atccggagat gtccgtcata ataccaaata cgccacctcc aatcgctgaa
    22141 ccaattacta aggcagcaag tggaattaaa ccaattcctt ttttctgttg ctctgtatcc
    22201 atgtaagcat cctccaaaat aaaaccgctt ttatcaaaaa gtataacaaa ccttttttat
    22261 ttttacttaa ttaataaaaa ctttaataga aatataattc taccggcttt tttctcatta
    22321 tacaagcaaa gcgcctagtc cctttccaaa ttacaccacc aaaaaactta aaaaagatgc
    22381 tatactaaaa ggaaagaatt ggaggatgat ccatgaacat tttatatata tcgatttcag
    22441 gaaatacgcg tgcctttgcc aaacatctag cagaatatgc tgaaaaaatg catgcagaag
    22501 atcctgtcaa tcctgaagtt actttaaaag aaatccatga aaatagtgat tttacgaaag
    22561 aaacagaacc attttttact ttcgttccta cttatttaga cggcggaaat ggtttagata
    22621 acggtgatac agaaatcttg accgaaacga tgcgtgaata tctggaacat gaagacaatc
    22681 ataaactttg tcttggtgta gtcggtagcg gaaataaaaa cttcaataat cagtattgtc
    22741 taacagccaa acaatatgca caaacatttg gctttccttt cttggcagat tatgaattac
    22801 ggggaacacc atctgatgtg acacgaattt atcagatttt agcagaaaac aataaataat
    22861 aaaaaagaag aagctgaaaa atagatttca gtttcttctt tcgtttctat tgtttctatc
    22921 atattaagct ttgacatcca tcacaggtgc ttttgctttt gctttacctg ttttttccaa
    22981 gacaaagttt tttacacgat ccatattggt taccaagacg atcatggatg tttctttgcc
    23041 tgctgctttg atcgcttcta agtcagcttc tgctacaagc gtatcaggtg tcacttgctg
    23101 cccttctgtt actttcacat caaatggcgt accgcctaag tcaactgtgt tgattcccat
    23161 atgaagcaag atttctaaac catttggcgt tgtgatccca atagcgtgtt tcgttgggaa
    23221 gacagagctg actaccccag taactggaga atagatatgt ccgttttctg gttctacaaa
    23281 gtagccttca cccatcatct tttgtgcaaa aactggatca cttgctttat ctaaagaaac
    23341 aactgttccg tcagcaactg atgagaggat agtcacactt tcagctgaag tttgaggtac
    23401 tactttttca ggcacttcat ttactgtggc tgtttcagtc gctaattctt ctttttctaa
    23461 acggtcttta ggaataccga agaagaatgt agcaacgaag ccaccagcat aagctgccaa
    23521 taatccaagg atgtagccta accatttacc gtcagagatc aatgggatca aagcggctcc
    23581 tgaaggtcca atagcgatag ccccgacatt tccgatcatt ccgatcactg ccccgccgat
    23641 acctccaccg atacaagcag taataaatgg gcgtcctaga ggtaatgtta ctccgtaaat
    23701 caatggttcg ccgattccta ggatcccgac tggtaaagct cctttgatca tttctgttaa
    23761 ttctttatct tttttgcagc gaatccataa tgccaatgct gcacccactt gtcctgcacc
    23821 agccatcgca agaattggaa gcaatagcgt acgaccagtt tcatcaatca tttgcacatg
    23881 gattggagtc aaaatttgat gcagtccgaa cataaccatc ggcaagaata atgtgcctag
    23941 aacgaagccg gcaaatgctc caccaacgcc aagtacccag ttgatcccac cgaccatgcc
    24001 atcagaaatg aaacctgcta aaggcatgat gaagaaaatt tcaatcagac cgatggcaat
    24061 caatgaaaga gttggtgtaa cgatgatatc taccgcatca ggtactactt tatgcagttt
    24121 tttctcaacg attgacaata gccaaacagc gaagatgaca cctaggatcc caccttgtcc
    24181 agctgcaaga gcttcaccag taaataagtt tttcagtggt gcttccggat tcatccctgt
    24241 cagcatcaca acggccccga taactccacc aagagttggt gttgcaccaa aaacttgtgc
    24301 agcattgata cctgtataga taactaggta gctaaacatc ccgtttttca agatgttcat
    24361 cacatcgata tattgttgcc atgttgctgc atcaagtgtt ccggctgtga ctaagtttgc
    24421 taaaactgcg gcaatccctg ccacgatccc agtaccgaca aatgcaggaa tcattggcac
    24481 aaagatatta gaaatgtctt ttaataccga tttgatttta gatggttttt gtttcgattt
    24541 ttgtgccgct ttcatttctt gtgcccgttc gtttacacgg tcttttccag atgctgatga
    24601 atttgctgta gctgtactta cagaagaaag tttttctcct aatttcacgc ctgccaaatc
    24661 aaccatttgc tgtgctactt tgttcacttt cccaggtccg atgatgactt gaagctgttc
    24721 atcttctact acaccaagca ctcctggaat cgcttttaat tcagagacat ttacaagatc
    24781 atcattgatg atcttcatac gcacacgagt catgcagtgg acaatgcttt ctacattgcc
    24841 catgccgcct gcccctttat aaatttgttt tgccagttct tccaaagtca gttcgttttt
    24901 tgccatggtc ttttccccct cataaggtcc cttttacaaa tccgtttgct tcagctaatt
    24961 ttgcttgagc ttcctcttta tcactatttg tcaaaatcat gacgatagcc agcttaacat
    25021 tttgatctgc ttcttcaaag tacttttcag ctgtttcgta atcagcttct gtcgcttgca
    25081 tgatgattcg ttttgagcgt tcgattagtt tttcatttgt tggtttgaca tcgaccatca
    25141 agttattgaa tactttacct ataccaatca tactgatagt agaaatcata ttcaagataa
    25201 gtttttgtgc tgttcctgac ttcaatcgag tagagcctgt caaaaattct ggacctgcat
    25261 cgacttcgat tgggaaatcc gcgtgtttac tgatttcggc ttgtttattg caagaaatcg
    25321 ttcctgtgac agcaccgatc gattttgcgt aatctaatcc accgatcaca tatggtgtac
    25381 gaccgctagc tgcgatacca ataactatat cattttttgt caaattcagc ttgattagat
    25441 cttcttgccc tagctcataa gaatcttcgg ccccttcgac agctacagtc attgcttctt
    25501 ctccaccagc aattagacct atgaccattt ccggttctac accgaatgtc ggtacgcatt
    25561 cagcagcatc taacacacct agtcttccac ttgttccggc tcccatataa atcagacgtc
    25621 cacctttttt aaaggactca atcgtgttag caatcactgg ttcgatactt gtcagttctt
    25681 tttcaaccgc agcggccact ttctgatctt ctttgttcat tagttgaacg gcttgagaaa
    25741 tactcatctc atctaatcca aaagtttctt ggtttctgcg ttccgttgtt aggttctcta
    25801 aattgatttt gctcattttt atcttccttc ttttcttata aattgatagt tcataccagc
    25861 tttgatttgg ttgatcaatg gtagctcttc tttgataact ttagctacta cattcacttt
    25921 ttcatccgct ggcaaatcat atttggttaa ttggatctca cccatatagc gcaaatactt
    25981 ttcgttatct aaagtaatag accctttcat acgcgtagct gtatttcttg ctgggatagg
    26041 cggaatctct cgaaaacgtg catctacgct tcgtatgaca tctcttgcat cgtcttgccg
    26101 attcgtatgc ttccctaata tatattcgta aaattcttca tctacaggtt ccgtatggag
    26161 caagactgtc tgttcttttt ggaaagaagc aaattgctcc tgaacgtttt ctgacagacc
    26221 tgcatctccg atgtaaacaa tatccgtgtt acttgctaat agatctagag cgcctgcaag
    26281 aggatggatc cctcgatgtt cttccaaagt tggcaatcct tgatatagtg ggcctctcaa
    26341 ctctgtatct cctggtacaa aaccttggac aaggagacct tgaattttga gccattgatt
    26401 ttttttctga taccattctt tgtccagccc tgtttcggga cgtggataat aattatgcca
    26461 agcttcaatc tgtgagaaat cagcttctgc ttctttcaat tcatcgatat ctttaggcgt
    26521 gatcgtgcta gcattcaaac tgattttcaa ttgatgtgac cagtcggcaa tctgctgatt
    26581 ggaaatatga taatccattc ttaaacctgt tacaccaatt gctttcaaag gcgttagatc
    26641 ttctaatgaa aaacccgctc gttccaatgc ctctcctgaa atatcgacca tcaattctag
    26701 tttattcttt ttcgcttcgc ttcctagttc gatcaatcgc ttttgatatg ccgaaacatc
    26761 atcttctggt atatgcatgg aagtgaaaat accgacaaag ccattggatg ccatttggcg
    26821 gatatactgt ttcttctctt ctgacaaaga atcgttcata aatattgaaa agccaaacat
    26881 attatccctc tttttctgta tccgtcttca tttctatgac tagagtatat atctaaagaa
    26941 acaaaatttc aatactttta ttaaaataat taaatttcat ttctaaaggt tgagtttata
    27001 ttatcaaaag aattgtcata acctaaaaaa ggcactgcta agcaaaagca gtgccttgaa
    27061 atattttatt taaataacac aaaaacataa ttactcataa gaaaccaatt ctgtattatc
    27121 taccatgaat gtaaagaacc cctcattagg catcggatga aaataagcat tgatcactct
    27181 tatcaaggca ttatggcaaa ctaacagata gacattttct tcgtcttcga tgcattcttt
    27241 caataaagga acgatccgtg catacacatc taagactgac tccccatttg ggaatcgtac
    27301 agcgaacgct aaacgtgctt tttgaaagtt ctcatctttg cttggcagtc catcataatc
    27361 cccaaaatcc atttctacca atcgttcatc aacggtcagc ggcaagctga gacgatcagc
    27421 aactgcttgt gctgtatctc ttgctcgttg aagaggggaa tggatgattt tcgtgattgg
    27481 aacaggcaaa tctactacct tttctgctag tttctgtgcc tgcatctgtc ctttttcagt
    27541 cagcggcaca tctgcccgtc cgcaaactaa tccttgtgcg ttccaagttg tttctccgtg
    27601 tctcgttaca taaagcatgt gattctctcc ttcgttggca aagttcccct taaccatacc
    27661 ttgttgttct tgagattaca agggttagat tctctcaaga gaaataatct cagtagatac
    27721 tttatccagg aaggtttgat catgttccac tagtaacatg gcaggtttca cgttcaagat
    27781 cagttgttct aattgttctt gattgaagac atccaaataa ttcaatggtt catcccatgt
    27841 atatagttca gctggctgtg ataaagattt agccaattcc acttttttcc gttggcccat
    27901 actcatctgc tcgatcttgt tatgaaaaac atctctttcc atcccaagct ttcggaggtt
    27961 gttcaaaaat gcttggtagt ctacttggtt tttctctgca aattccgcca acgttcctcg
    28021 attgtcttca taattttggc ttgcataact aatgctcaga tgttttggct ggtatttttc
    28081 tcctataacc ttgccgttga atgcccccag aagataatgg ataatggatg actttcctgc
    28141 accgttagga cctgaaatcg ccacccgctg atgaggctcg attgtaaaat gaattggctc
    28201 gaataacaga ttttcatacc ctaattgaag atcttctacg cttaaaagtc gcttatggtg
    28261 agacgcttgg ctattcatcg tcaaagaatc gatatattcg atatctttta atagtttttc
    28321 tttctcgctg atctgggtct ccatccgatt cacgattgct ttggatcgtt tcatcgtccg
    28381 tgcagcatca gcacccactg ctcctttatt cactcgtcta gattcagtat cgatgaatcc
    28441 gacttgtttc tttgttttat ctccttctcg ggaacgagac cattcggctt tttcagctgc
    28501 tgttttcttt agcctactga cttctttttt caatttttca ttttgagcca tttcaaattc
    28561 atcacgaagt tttttctgtt cttcatagat agagaaattc ccttgataaa gttccagttg
    28621 acttttttcg attgctaaaa catggtccac tacttcatcg ataaatcccc ggtcatggct
    28681 gaccacgatg aagccttgtt ttttcttttt caaataagcc gctacttgtt ttctaccaga
    28741 gatatccaaa tgattcgttg gttcatcgat taacgggaaa tgagtgtcat ccacaaataa
    28801 aagtgccagt aggacttttg tcttctctcc ccccgatagt gtgctgaatt ctctccataa
    28861 gatttcagga tctgtttgca tcaattggag ctctctttcg atttcccata tctcaaaatc
    28921 cgtaatatca tttaacacgt aataggttaa acgttcttta tcttttgtct gttgcgggaa
    28981 ataggcaaat tcttgctgat ggattacttg cccttgataa ggtagtttgt tttgtagaat
    29041 attcagtaaa gttgtctttc ctcgaccgtt tcgtccgata agtcctagtt tccattgtgt
    29101 gtcaaaattt agatttgctt gttcaaataa taatgtgcct tggctgtcgt agccgaatgt
    29161 cagatttttt atttcgattt tagacatttt ccatcacctc gtaaaaaaag accagtccta
    29221 ttttcagaac tggctaaaga ggatgcaagg gttggataca cacaaaaaga cccatacatc
    29281 gaaaaaacca agccaatccc gaaaatctgc acactgcttc cttgtctcca caaggtacag
    29341 tctgaatgca gctttcatca atcgacttaa tttttcaatg cacggatccc tcactttgtc
    29401 ctatatttga aattacgata gcataaagaa aatgattttg tcaactactt cgggaggatg
    29461 gtgaaaaatc tgctaagtgt ctgtcctaag atttttgttt tttctaatgt ttgcctgtgt
    29521 tccattgctt cttctaaacc tattggaccc aaatgaatac ttaagacaat tgggagaaaa
    29581 tcagaaagtc cttctagctc ttggtctcta cttccgcaaa tagcgattat tggttttcga
    29641 tatttttttg caagcactgc tacaccgtat ggaacttttc cgtggatcgt ttgctgatcg
    29701 atccgccctt ctcctgtaat gatgacatct gcttgttcga tctttttttc caatccagtg
    29761 atttggctga ctaaatcgaa accagaaacc atcttcgctc ccaacaaaaa aagggctcca
    29821 ccaataccgc ctgctgctcc acttcctgga atatcatcta aatccacctc ccagaaatct
    29881 tttatttgct gagcaatctt tcctgcttgt ttatctaaga aagctagcgt cgtatctatt
    29941 cctccttttt gtcttccaaa ttgccaagca gctccttgtt gacctgtata tggattggta
    30001 acatctgcag cgataatcaa ttttacttta gaaacaagaa cgtttcttcg atcaaaatga
    30061 agttttttag tagataataa aggatttcct tctgtgtacc cttctaaaga agcacccaag
    30121 gattggagta atcctagacc accatcgcta cacccgcttc ctcctaaagt gacaataatt
    30181 tgttctactt cttgaagcag tgcatcttta ataagttctc ctaaggcata actggaagca
    30241 agtcggatag tttgatccgt tggtttatca agtagatcta accccaatgc ttgtgcagat
    30301 tcgatgactg cggtgttttt tccttgccaa gttgtcaata aatagctgat ttttcgctga
    30361 cggaataaga gatccatccc atcaatggta cgccatgttc ccctgagcgc gtaatagatt
    30421 gcttctgcag tattttctcc gccatctgca atcggcacat tgatttttct tcctttacga
    30481 tcttcccagc catttagaac tgcctgattt agttcaaatg aagaagcact tcctttaaat
    30541 gaatcaattg ccgccaaaat atccatctgt atccctcact ttcttcttaa gtaagacact
    30601 ttttttcatt tttttcaaac aaaacaatgc tattttcttc catttttcta tatactaaaa
    30661 gggaactcat tgaataaagg agagaaaaaa catgaaaatc gcaatagctg gggccggagc
    30721 aatgggcagc cgaatcggat tgatgctaca tcaaagcgga aatgaggtcc tcttgatcga
    30781 tcgttggcct gctcacattg aagccattcg tacaaatggg ttgattgctg actttaacgg
    30841 taaagaagtg gtcgcaaaac tgccaatcta ttcaccagaa gaaatcatcg aaagcaacga
    30901 acacgtggac ttgatcgtag cattaacaaa agccaatcaa ttagatgata tgttttgttc
    30961 gatccaatcc attattactg acaatactta tgttttgtgt ttactaaatg gattaggtca
    31021 tgaagatgta ctggaaaaat atgtgccaaa gaaaaatatc ttatttggga tcacgatgtg
    31081 gacagctggt ctagctggtc ccggaaaagt cacattgtta ggtgatggag aaatcgaact
    31141 agagaacttg gaaccagaag gcgaagcatt tacaaaaaaa gttgtagaag tctttcaaga
    31201 agcaaattta aatccgatct atagccataa cgttcgttat tccatttggc gaaaagcttg
    31261 tgtaaatgga acattgaatg gtttatgcac gattttggat tgtaatattg ctgaactagg
    31321 cgcgcaaaaa gcggcagaga gcatggttcg aacaatcgta tctgaatttg cttctatcgc
    31381 agcaaaagaa ggaatcatac tagatcaaga agaagtgtac caacatattg cttctactta
    31441 tgatcctgac aacatcgggt tgcattaccc atctatgtac caagacctga tcaaaaacca
    31501 tcgtttgact gaaatcgact acatcaatgg tgccatttgg cgaaaaggac aaaaatatga
    31561 tattgctaca ccatattgtg cctttttgac ccaattagtc catgcaaaag aaggaatcct
    31621 tggcgcagaa taaaaggctc tctgatgaga atcagctgaa tcagcagctg gttctctttt
    31681 tttaagccca ataaaagatc aaaaagaaaa cacaactctc atgatgccat aagaattgtg
    31741 cttgtttgtt tcagtacata atctcttcaa aatgtaggtt ttttatttgt tttcaacaga
    31801 ggagaggtca tattcgtatt gctcataaat agtggaatcg ttagtgataa atcgttttgc
    31861 ccaattttct gcatcataaa attccaatag ctctgatagg attggcttaa atggtgtatg
    31921 cagaaattcc ggtaattcat ctaaatcacg ttctcgaagc aaaaaaatat tttcaggacg
    31981 ataaaaatga taatgagcaa tcgcttgatt atccgtcact agtttctttt gaaaatacat
    32041 ggattcaaat gtccgcaaag tcactccttg ctgaccctcc cgcaacagtt ccagaatccc
    32101 gcgcgattcc cctgtttttt tcaggtactc ttcataagta agatatccag gttgttcatt
    32161 ccctcgatgt ggaagaatga aatagttggt cgtaacatct ctttttataa attcctgctt
    32221 atagctttct gctcgttctt ttctcccatt attcgttgca ccaaaaaata gatccgtctt
    32281 tggttcgcta gaagaaaaat tcatatgttt cgaataaaat gaactattat gtttcagccc
    32341 aagttctttt gcttccaaaa aatcaaaatg ataaatctca tcgattgccg gttcatcttg
    32401 tgcctgcttc agcatcgcct cgtgttctgc tttgaagtga ttccaaaaaa ataacacaat
    32461 ttttgcattg gtaaatgggc gcacgcgtcg agccatctcc atatcaaatc cataatctaa
    32521 aaaaacgatc agctgataat ttgccaactg ttgtctagct gatttaatga attccgactg
    32581 tagtaaatct tttccggacc aaacatctaa agagcggatg gaaggcaaaa aataaagtga
    32641 tttatttttt gcaactagca gtacgtcatt tttgttcatc ttttccgcct cactttctct
    32701 gtcacttttt cctatgatag cctgtttaaa tagtaaaaag ccagtaaaac gtttcctata
    32761 tttgtatgaa aatttaacat ttgtatgaaa atatgatgaa ataaatcatt cttctattaa
    32821 aattcgccta aaagttttct gaatagttgt aattgtctga aaatttgtta tcattagtca
    32881 ttgttaaata ttgctattta ttcttaatat aaattttgat tgtgaattta aaagaaagag
    32941 gtcatttatg gaagataaaa aattgaaaaa acaacttagc tccagacata tcaccatgtt
    33001 agctttaggt ggagcaatcg gtgcaggtct atttaaagga agtggcgaag cgattgggat
    33061 cgccggccct tctgtattga ttgctttttt gattggtggg ctgattttat atatcgtgat
    33121 gaaaggtctg ggaaaaatcg ttttaagcgg tggcgacacg catcacggat tatctggttt
    33181 gatacgccct tatctaggtg ctcattctgc tgattttact gattgggtct actggtctat
    33241 gtggattatc aatatcatcg ctgaagctgt tgcagctgct tcctttttgc agttgtggtt
    33301 cccgcacatt ccagcctggg tatttgtttt tatgttggct gttttaacta cgatcatcaa
    33361 tctttattcg gtacggttat tcgcagaaac agaatattgg ctggcttttg ctaaaatcag
    33421 tgtcattatc ttactgatca tttttgctac ttatcttgtc ggtcagcaaa tgttgggcac
    33481 aggcgttttc cctacccttc agcaattgac tgaccatggt gggtttactc ctcatggtat
    33541 gaagggaatc atcagttctt tgcttgtagt tatctattct tacggcggtt ctgaactgat
    33601 tgctatcacg gtaagcgaag cagatgatcc taaacgtgcg attcctaaag caatcaaagg
    33661 tgtcatggga agaatcattt ccttttacat cattcctttg tttttgcttt tgattctttt
    33721 tccttggaat actttagcag gcacgaatgt cagtcctttt gtgatggtat ttgaaaaaat
    33781 gaatatccca tttgcagcgg atatcgtcaa ttttgtgatt gtccttgctt tgttctcatc
    33841 tatcaattcg ggtgtgtatg catcttcaag aattttgttc ttccgtttga aggatcgaaa
    33901 aggttcctct agaaaactag ctgttttaaa caagcatcaa gtaccgcaac gtgctgtttt
    33961 attttgtacc agtgttcttt atcttggtgt agctctttct tattttgtcg gtgacaaatt
    34021 atttggctat ctggcaggtt ccctttcgta tacagtatta ttgatctgga tcattatcag
    34081 tgcggcatcc tttgtactgg cactaagaaa aggaacatta tgggataaag gaatcagctt
    34141 ttttgcatta gctgtcttag gattgatttt ccttggtatc ctgttcacga actccattgg
    34201 ggtaactgta ttgactggcc tgctttacct gttcatttat ttcagttatc aaaaaaagaa
    34261 tgatgcgttc gtattgacga atgaatgaaa tcgatagaaa attttatttt atttatgtgg
    34321 aatagatgga gctattgaag aaaggagttg tgacaaaagt cttgttgcaa ctcctttttc
    34381 cgaataaaca gtctcatgac ctcttggtaa acggtgttca aaaaccctct gtgcaaaata
    34441 attgattgtt ctccatgctc atgacatgat agaagaaagg aatgaaaaaa aggagtttgt
    34501 tttaaatgaa aaagtattgg aagtttttgt tgatgatcgg tgtttcaacg gtagttatgt
    34561 ttggtatgat gtacttgaat gtctatgcgc tcgatcatat cttcttcagt cgtacacgag
    34621 tattcatggc gttgatgatg ggtgcagtca tggcagtcat catgctgttg ttcatgtgga
    34681 aaatgtatga aaacaaaaag ataaatgtta tgatcttagc cgctagtctt cttgtttttg
    34741 ccggttcctt gtttatggta cgaagccaaa ctactgtcaa cgacacagct tggatgaagg
    34801 ccatgattcc tcatcattct atcgctatcc tggcaagtaa acgagctgat ttaaaagatc
    34861 ctgaagtaaa aaaattagcg gaagaaatca ttcaggcaca agaagaagag atcgacaaaa
    34921 tgaaaaaaat gatcaaagaa atggaatgac cattatccgt ccaaataaaa aaagaggatg
    34981 ttccagaagt tatcagcttc aagaaataag aagaagctac ttctggaacg ccgtgaataa
    35041 ggggttgtga aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagcttc
    35101 tcctattttt cgtttggtta ggcttattac cgcagatgca agcttttgaa caccgtttat
    35161 taagaggttg taaaatcagc gttctgacct gagtattaga gagacaaatg gaaaaatagt
    35221 tcctcatatt ttgccatttt ttgagctaat accgagggtc agctgattga acaccgttta
    35281 tcgagaggtt gtgaaaaagt cgcttagttt cgcgtattaa gaaaaatttt gtgaaatggc
    35341 tttccacatt tttgtataaa tttggcttaa taccgagaaa ctggcttttg aataccgttt
    35401 attcgtaaaa gggattgtga caaaagtctt gtcacaatcc ctttttatgt ttttattgtt
    35461 ctaattgcgc tgtcttgctt actgcttctt gcggtttcac aaattttttt gagattcccc
    35521 aacctgtgaa ggcactgacc atcgaaaaca caggagaaag caaactgaaa aatacgaatg
    35581 gcaagtaagt gagtgtagga ataccaaatg tacttgctac gaaacttccg gcaattcccc
    35641 aaggcactaa gtagttgatt actgttccac catcttctag cgttctacct aatacagttg
    35701 gatcaaatcc tgctttttca taagtttctt taaatgcatt accaggcaga ataacagata
    35761 ggaattgttc accaataaaa atatttactc cgatacttgt catcaatgtt gtaaaaatca
    35821 aatttggtgt gttcgtcatc tttcttgata ctcgttccat cacggttgag atcaagccaa
    35881 attcgatcaa caatccacct aatgacaaag ttagaataat caatgacaca gtaggcatca
    35941 tactttcgat tcctccgcgg ctaagcagtg aatcgatttg ttggtttcca gtatttgaaa
    36001 caaaccctga ttcgatgacc ccagccaact tcgttaagga agtttgtggg ttttgaataa
    36061 aaatcattcc tactgctaca gcgatattca acaaaatcgt taaaattgcc ggcacctttt
    36121 tccatgcaca cagtaacatt aaaaataaag gaatcagtga ccagattgaa atagtaaagt
    36181 ttgcttctag aacatcagtc acttcacgaa tagatgaaag acttgcggct ttacttgtgt
    36241 gtcctaaaat catgaataaa aagaaagaaa caacaaatgc cgggacagtt gaccacatca
    36301 tatgcttgat gtgtttgaac aaatcggcat caacaatagc tgctgctaga tttgttgatt
    36361 cggataatgg agacatctta tctccaaaaa cggcacctga aacaatagct ccaacaacca
    36421 gcgctggatt taagcctagt gttgtcccaa taccgaaaaa tgcaatccca atcgttgaca
    36481 taacagtaaa ggcactccct acagcgctac ctacgattgc acacacaaca aatacagaag
    36541 ggacaaacca ctggacactg atcaatttga acccaatgac cattagagtt ggaatgatcc
    36601 ctgcttgtat ccatacagca atcaatgaac cgactaaaat aaaaataaag attgggatga
    36661 ttcctggttt gatgccattg atgattcctt cgtgcagcca atctgtcggg tatcttttta
    36721 tcactgcata caacatgacc attccgatcg ctgctaagat cgtgatatta ggtgagacct
    36781 ttaatccgac aacgccaatc gcaatgccta aaacaataac cattaataca agtgttgctt
    36841 ctaaaaaact tggtgttcct ttttttccca tgataatctc tcctttttta gttgttctta
    36901 tgttctaaaa aagttaagat atcggattac tccgccgcaa ttcatccgcg attcctcctt
    36961 tataaaaata aaaagacctg ttttaaacta aggacgaatg actccgcggt accaccttaa
    37021 ttaaaaacag atctgttttt cactttcaaa cttttattca aatgtatgga ctttccatgt
    37081 aattcgtcaa ttaggcttga tcggttcaca gcgaccaccg actttctgaa caaaacacct
    37141 aaccgctact gcgtgaaaag ttgacttgta cgaagtttac cttccataag atcatttgtc
    37201 aatgaaaaag aaaatatttt ttcatttttc tgaaaattat ttttataact ttcacacaca
    37261 agtttatttt ttactagaaa gtagcgccct cttgtttttt tcttgctact atttcttgat
    37321 gttcttgctt gattctttct aatagctttg gctctttcaa cagatcaaga gctgtattgg
    37381 cgagtagttc tgctgcaatc gcaatagaag caaggccttt gtcactttta gcagcagctt
    37441 tgaattcttc tgtgtgtccg gcaatatatg tctcagagat tgctaccgta ggctggattg
    37501 ttggtatgac ttggctgaca tttcctacat cagaagaacc gagacttgtt ctttgttccg
    37561 tttctatttc ttcatctgga acacctgctt cttttgcatg ctggaagaat aagtcatcaa
    37621 aagaaggagt aacgatgaca tcatcaactg cattttggaa caatccaaac tcaaaagtcg
    37681 tgcccgtact tatcgcagca cctcgtacga tattttccac tttttcatat actttatcta
    37741 atgtttgccg atttcctgca cgtaaataga aacgtccagc agcgtaatct ggaatgacgt
    37801 tggcagctac tcctccgtct gtaatgatcc catggatatt gacatctttt ggcaattgca
    37861 agcgtagagc gttgattcca ttaaacactt ggatcaatgc ttccaaagca tttactcctt
    37921 tttcaggtgc tgctgctgca tgggaagcga caccgtaaaa tttgatgtcg actggatcat
    37981 tcgctaaaga ttctgtcgtt ttcccataac gaaaagctgg atggacgcat aacgctacat
    38041 cgacatcctc aaaaaaacct tctcgaacaa agctgccttt agctgatccg ttctcgcccc
    38101 cttcttcccc tggggtgcca tatacacgga tttctccacc agtttcatca atgaattgct
    38161 tcactatgct ggcggctaat acggagtaag taccaaacaa attatgcccg catgcatgac
    38221 caatacctgg taaagcatcg aattctgcca aaaaggcaat tgtgggaccg ggtttattgg
    38281 aaatataacg tgcatcaaag gctgttcggt gtccagctac ttctttttct acccaaaacc
    38341 tttctttttc taattgttta atcaacgctg ctgaggaata aaactcatag ttacttactt
    38401 caggatgttc gtggatatct agagcaagtg cttgatattc tggtaaacga tattggatta
    38461 gatccttcaa ttggtttgtt gagattgttg ttgtcataaa aaattcctcc tatgctagtc
    38521 atttttctta ttttctcccg aatgtttccc atgcaggcac gcttgatcct tttgatgttt
    38581 tctcgattac tttgactgtg tcttctgttt gataagcgtc tactattttt tgatacgttt
    38641 tattgttttc atcttctttt cttgcaacga tgatattcac ataaggacgt gcatggtcat
    38701 ccactggttc taagaagatg gcatcagaag caggattaaa tccagcatct acagctacac
    38761 cgctattgat cactgaaatg tctacatctg acaaagcacg tgctgtttgg gaagcatcta
    38821 attcagaaat gtctagattt tttctattct cggtaatatc agaaacagtg ggcgcttgtc
    38881 cttttgcctt atccactttg atcaatccag cagtttgcaa taacagaaga gctctgccgc
    38941 catttgtaac atcattaggg attgctactt ttgctccgtc tttgatatca gctacatcct
    39001 tcaaagtgtt agaataaatt cccagcggtg cattgacagt atttccgatc gatactaaat
    39061 cagttccgtg ttctttattg taattgtcta aaaagaattg atgttggaaa gaattcaaat
    39121 caatcgatcc atctgctaaa gccacatttg gttgattgta atctgtaaat ttcacgtatt
    39181 ccaaattaat gttctccttt ttcaaacggt ctttcacgtt gtcccataca tctgtatctt
    39241 ctccaataat ccctagtttt acgatagttt cttttttgtc agttgtatct gcttttcctt
    39301 ggctacaccc tgccaaccaa ataattgcta caaatgtaat gactacaaaa cgaataattt
    39361 ttttcatttt ttctcctcca ctttcaatgt gtaatttttt taatcagttg attactgata
    39421 aattgactta aaaaaactaa gattagaatc aataatgtag ccacaatcgt tacatctgtt
    39481 tggaatcgat tataccctct cgatatagca agattcccta atccgcctgc acctactgct
    39541 ccagccatgg tagtcagtcc gatcacgttg atgatagtca acgccgagac ccgaatgata
    39601 ccaggcaaac cttctaacaa atacacacgt aaaatgatac cgattggact ggttcccatc
    39661 gcttctgccg cttcgatcac cccaggatca acttctagca gtgcgttctc gatttgacga
    39721 gcaaaaaacg gaacaactcc aaaaatcaat ggcactaaag ctgctttcgc accaatcgtc
    39781 gttccaacta agaaacgagt agtcaatgct aaaagagaaa gcaagataat gaaagggatg
    39841 gaacgaatga tattgatcag cttatcaagt atttcaaata gcagacggtt agctagtaat
    39901 ccattagggc gtgtcactac taacgtcaca cctaagatga ttccaatcat cccgccaatg
    39961 aatgctgtcc aaaaagacat atatagtgtt tgcttcgtcg cttcgacaaa ttcatccgga
    40021 atcaaataaa cattgggcaa atatgtttta aagaaatcag tcattttatc ttcctccttc
    40081 gatcactttg atacgactat ctaaatcgtt tttttgtaaa atatttattt ttacaccaga
    40141 tttgatcaaa taatccaatg cttttttccg ctgtttggtt tctccagcta aagtaacgat
    40201 caaactccct aacggcgttt cttgtaataa ctctacattg ccatataaaa tattcgctgt
    40261 tacttgatat ttgctgtaca gatgagcgat tagaggttcg ttcgtctgat ttccaatata
    40321 acttaattcc accagccatt tattggcgat ctgatcggca aaagcagaat gggcaatgat
    40381 cgtttctaat gcttggtcaa gatgagtagc tgttcgaata aaatctttgg tcaattcttc
    40441 ttcaggattg ctgaagatct ggatgctgct acctttttca acgattcttc catcttccat
    40501 aaccgctacc ttgttgcaga tttctttgac aacttgcatc tcatgagtga tcaggacgat
    40561 tgttaaacct aactggcgat tcaatttttt taacaatgca aggatctgaa gggtcgtttt
    40621 cggatcaagt gcactggttg cttcatcaca taataatacc ttaggttcat tcgccaaagc
    40681 tcgtgcgatt gctactcgtt gtttttgtcc ccccgacagt tgtttaggat aagcagatgc
    40741 tttttcttcc aaaccgacaa gttccagtag ttcattcact ttttgacgac gttcctgttt
    40801 cgattttcca gaatacttta aagaaaaatc aacgttgtca aaaatagttc ggctttccat
    40861 tagattgaaa tgctgaaaga tcataccgat ggcctttctt tcttttcgca attctttggg
    40921 agagagctga ctcagattcg tctgattgac aatgacttct cctgctgttg gtttctgcag
    40981 caaattcatc acacgaacta acgtactttt ccctgcacct gagtaaccga cgattccata
    41041 aacatcgcct ttttcaatcg ttaaatctac agaatctact gcctgtatct ctttttcttt
    41101 ttgtttgaaa catacagaaa catctcgcaa ttcaatcatt aaaattcctc cttatctaaa
    41161 aaaagcgtcc tcaagaaaat gaaaatgtca ttttcttgag gacgcttttt tgcgtgttac
    41221 cacctcatgt tcaagctgtg ttcacacaca actcctcttc aagtacgatc atactctagc
    41281 aagatatcgg tcgcagccgt catcgcctta catctatgct cgggatgaat tgctcgatgg
    41341 ccattttcca atagtcgttc cttgcttctt ctcagctacc gaagctctct gtcaaaggtt
    41401 cttctatcgt acttaccatt tcaatgcaaa taatattcaa aaaaaaagtc cttttactaa
    41461 cataaactat gtcagtaaaa ggacgacgta tcgcggtacc accttttttc ggaagtttcc
    41521 ttccctcaag cccaacatct caaaaagaga gattggcgtt cgttttaacg gtcgaacagt
    41581 tccgaatttg cctacttatc gacaaattat tctccaaggc cattttcagc ttttcttact
    41641 tgactcttct caccagccag agcctctctg caaagtttcc aaacttactt tccttttcaa
    41701 cgaaatcgat attttgttgt tgggattaat ctacatgagg aaaactgaaa agtcaagtac
    41761 gaaattcaaa ttattttttc tatatttatt tttctgtttt tttatttaac atttcaataa
    41821 cagttcgaag atcttttcct tccgcaagaa gtttcaattt ttccttttct tcgacggtat
    41881 aatttcggac aaaactggaa tcaggtatca aaacaacgcc taatcctgct cgtgaagcag
    41941 ctgttgctcc tactaaagaa tcttccactg caaaggctga actagcttct aatcctgttc
    42001 gttccaaagc tgtcagataa ggaatcggtg aaggcttgtt ctccgacact tcgtctccga
    42061 atgtaaacgt gtccaagtaa tcagctaatt taaagtgatc caagatatct gttgctcttt
    42121 tcgtaacagt ggtcgtagca atgcctagtt tcatatgacg ttcttttaag tctgccaata
    42181 tttcttttgc atatggtttt aagtggatgg ctccgcttgt cagctgttga taaaaatatt
    42241 cttcacgctt cgctcggact tcctgtactt tttcagggct acctgctgct ttcactaaaa
    42301 tatcaaaact ttgtttccag ttttttccgc cccaagcgtc aacgatttct tttgggatat
    42361 ggatatcaaa ttgctgaaat ccccaaagcc agccatcacg atacgttttt tctgtgtcaa
    42421 ctaacaaacc atctaaatca aatattgcac ctttcatcta tacattaatc ctttccaaaa
    42481 caatacacat agtttagcac gactggtcca aaaagaacag aagcaaagaa ccagccttct
    42541 cgtttataag agttcttgga atcgacggat atagattttc ttcacagctg tcacaagcgc
    42601 cagataagcg atgactgtag caaataacca taaccagtaa ttgccaggaa gtggcatcaa
    42661 gcctaattca gcaccaaaac ttgtaaaagg aaggacagaa ccgacaataa ttcctaatgt
    42721 agtgataaca aacatggcaa atgttgcgtt gctttggata aatggtactt tcggtgtacg
    42781 cagtgcatgg agcactaagg tttgtgtcca tagtgattcg acaaaccatc ctgcatggaa
    42841 taatgcgatg aaaatcactc gctgtgaact atccaatgta tggaaacttc cgcccactac
    42901 agcaggacaa ataacaaaat acatcaacaa gtaagtagta atatcaaata tcgaacttgt
    42961 tggaccaaag taaaccatga attccccaat actagatgca ttccattttt ttggctcgtc
    43021 caaatattct ttatccatcc gatcccatgg caaggaaatg caggaaacat catagatcag
    43081 attcaaaaac aaaagttgta aaggcagcat tggtaaaaat ggcaggaacg tacttgcaat
    43141 cagcacggaa aacatattgc caaaattaga acttgctgta gccttgatat atttcatgat
    43201 attcccaaaa gtttctcgtc cagaaagaag gcctctttcc aaaatcgtca aatctttttc
    43261 taaaaggatc acgtctgcag attctttcgc aatatccaca gctgtatcta cagaaatacc
    43321 gatatcagcc actttcattg caggagcgtc attgatacca tctcctaaaa atccgacagt
    43381 atgaccattt ttacgtaaag ctgtcgtcaa acgtgctttt tgctgaggat tcaattttac
    43441 gaatacttca tggtcttcag ctacttgtgc taattcatga tcactcattt ccgagatttt
    43501 ctcaccggta accaattcat tgatctctag acctacttga cggcacactg aacgtgtaac
    43561 taattcgttg tccccagtca gaacttttac agctacacca tgttctttca gagctttcaa
    43621 cgcttgtttc gttgtttctt ttggtggatc aaggaaagca agataaccaa tcaaaaccat
    43681 gtctgactca tctttgactg aaaattctcc aacgacgctt ggattggtct tttgtgcgac
    43741 accaatcact cgtaagccat cttcattaag tgactgtact tttgcaagta cggcttcttt
    43801 tcgttctttt gttaatggtg taacagtacc gccaagatca ataaatttag aaatgttcag
    43861 catttcttca atcgcgcctt ttgtgatcat ttgtgtttta ccagctggat cagcaaccac
    43921 aacactcata cgacgacgtt caaaatcaaa aggaatttca tccacttttt gataattgat
    43981 cttatctgta tctaaagttt ctgttgcttc atcaatgata gccacatcta acaaattttt
    44041 cagccctgtt tgatagtagc tatttagata cgcatggcgc aaaacacgat catcttcatt
    44101 tccttcacaa tccatatgat attcaagaat gattttatct tgtgtcaatg tccccgtttt
    44161 atccgtacat aacacatcga ttgcaccaaa gttctggatg gcattcaaat ttttgatcac
    44221 tgttcctttt ttggccatca cacttgctcc tttgaccaaa ttcgtcgtaa cgatcattgg
    44281 aagcatttca ggtgttagac caactgctac agatagtcca aaaagaaaag cttctagcca
    44341 atcccctttt gtaagcccat tgatgacgat aactgctgga gccatcaatg acataaattt
    44401 gatcagtagc atggatgttt tatggatgcc taattcaaag cttgattgaa ttggtttttc
    44461 agatagcgtt tctgctacat gaccaaatag tgtttcattt ccaacagaaa caatgattcc
    44521 ttccgcactt ccactgatga cattacttcc cataaagaca agattttcgt aacttgtttc
    44581 gctttgctga tcgtcttcac atactttcgc atgcttttct actggatagc tttcccctgt
    44641 caatgctgct tgggaaatga ataaatcctt tgcggacaat aaacgcatat ccgctggtat
    44701 catatcccct gctgaaagcc gaacaagatc tccacagacg atttcttcca taggaatctc
    44761 tgtgtacttt ccattacgtt ttacagctgc cgttactttc acaagtgatt tcagtttttc
    44821 agccgcttga ttggaacgta cggactgaat caacgtcatt gtcccgctga cgataaccat
    44881 agtgaagata atggctacac cgaaaagatc tttatctcca ggagctgcta atacatattc
    44941 cgtgatgaat gaaataattc ctaatgcgat caacactaat gtaaatggcg tgatgtatgc
    45001 tttcaatatt tctacaatga atggtgtttt tttgccatat gaaatcgcat tttcaccgta
    45061 attttctctt gaacgttcga tttgttcttc tgtcaatcca tttgctgatg catggaatag
    45121 ttcaaataat tcttgtttcg tttttccagc aaaagctgca tagatttttt gtgtatcttt
    45181 ctttttttcc atctcaatct ctcctttgtg tccaaaagac agctgttctc gctgcttttg
    45241 gtctttagct attcatcgga tcgatagaga aaaaactgaa aggggctgag aacagataga
    45301 taatagccct ggcctttcct ctagatcctt gtttttcgaa tgactgtcat ccatttgttc
    45361 tcatctcctt tactaagtaa ttttaattca tgacttccaa tcatttttcg aatagttatt
    45421 tttccaatta gaccacctcc tttttatttt tcaccgatgg ggatttgcgg caacaaaaaa
    45481 acctctcgcc aaatactcag cgaaaggttt gaaaaagcat attaaaaaaa gcttctcaga
    45541 tctcatcgtt gagttttgac actgtacaac gtaaaaagca gatacctgct tttagctacc
    45601 ttatgaaaag ccttatctcg acaattcctg ttctacccat tggcgtctct cgacgttttt
    45661 gggcagtagc ctatgtttgt ataggagcct cacctaacaa atcttattcg gttttccttc
    45721 gttaatataa caactaaaaa agaggatgtc aaatcaattt tccatgtttt tcatactttt
    45781 tttaaaatac acacgttata ttcctgtctc acgcggtttt atttgtctca ttttccacct
    45841 cccgctataa tagaaatata gtaggaaacg aggtgctgtt atggaaagaa cacttgttat
    45901 tatcaagcca gacggcgtga gacgccattt agtcggaagc atcatccaac gttttgaagc
    45961 aaagggactg gccattgctg aaatgaagtt tgaaactatg actcctgaat tagcaaaaga
    46021 acattatcag cacttgactg agcgcagttt ttttgatgaa ctgatcgatt acatgacttc
    46081 cggtcctgtc gtttatcttg tgctggtcgg cgaggaagtg atcgatatcg tccgtaagat
    46141 ggttggagca acaaaagctg ccgatgctgt tccaggtacg atccgaggag actacgcgct
    46201 gccggggact gaaaacatca ttcacgcttc tgattcccgt gatgctgcgg taaaagagat
    46261 cgcccgcttt ttcccgccat tcgatataaa caaaccgtct gaaaaagcgg cgaagtgata
    46321 caaattctaa actgctggtc tagttgctgg gttcagcaat ggccagcagt tttttctcta
    46381 aggacctccg ttgattcttt cctaacatat attcgagcac tgtgaagaat tcttggtagt
    46441 ctttcgtctt ttcttcccct aaagcagcag aaatcaatct ttgataataa tctgccatca
    46501 atgtttcata gatcactgta cttctttctt tatgtgataa gctccgtttc atatcttcat
    46561 tcacactacg tgcctttttc aaccgaccat tttctatata aaacgaagtc aggttcatta
    46621 aaaaagtaaa gagatactgc tcatgattgt tcaactgtgc taatcgtcgc attctttttt
    46681 tgattttcaa ataattgttc tcaatgaacc gatcactgaa tatccaagga aaatcagcta
    46741 gaatagatag ttcaaattga ccatagtctg gtatctgcat caagtattct tcaatgattc
    46801 ggcattcata acgtaaaaat tcaaattctg tctcagatac ttctgttttt tcgaccatgt
    46861 gaagattcaa aaccaaataa tacagatctt ctgttttctt aaaatgccta cggttattgc
    46921 tgatctcttt ataaggatca aagctgtctt cttgtacccg atctagcatt cgtctttttt
    46981 tctttaactt tattggttca tccagctggt ttcgcatcca ttcatattct gcaagtgtca
    47041 tgttcattcg ctctaaaaat gatctcaatg ttacaaatga catttttttc actgaatttg
    47101 tctcaatccc gactagagaa gtcttaaaac agattccttc cgctaattgg gactgtgtca
    47161 acttcttgtt gactcgaagt ttcttgatca attcaccatc atacataata gttctccttt
    47221 ttaatttaaa tttttccaca ttcaataaat agatacgtta aaaaggaaaa atacacgaaa
    47281 aaaataaaaa aatgtttttt tcataaaaaa taccaacctt caagcattag aatgttgtct
    47341 aactactgaa ggttggtttg attgtttatt gattattttt ttgctgttca acgtctgttc
    47401 ttgttactgg atataagttg gttgttgttt tattaccatt ttttgaaaag acacttgtcg
    47461 aatgttcgcc tttttgcttt tcgattgctt cattacgttc cgcttcattt ttatagtcat
    47521 attttttcgg atcaatcgtc tcaaatccgt ttggcacata aaaccgcaag agattttcct
    47581 gattcagctt atctgaaaga cttaacgcag tcttgacttt ttcctgatct ttggagattt
    47641 cctcatcgat tcctgctgct ttcgtatcga tgatttctcc tgtctgatta ttgtaagctt
    47701 ttcctcctag gacggtgtat ttgggtgtca caaagttccc atttcgaaaa gcaactactt
    47761 gatcatgctg agaagataat aagtctgtac caaaatgaag ataatcttta tcatcgattc
    47821 ccaatagatg tagtaatgtc ggcaaaacat cgatttctcc accgtattca tgattgactg
    47881 tccctttagt ataaccaggc atatggatca tcaatggcac tcgttgcatc tgtgcgttgt
    47941 caaattcatc ccatgtatct ggatctttac caagagcgct tgctaaatct ttattatctg
    48001 tattcgagat cccaaaatga tccccgtaaa tcacaaagat tgaattttgg taaataccag
    48061 attttttcaa atacgtaaaa aattgttcca atgattgatc cagataatgt gccgttcgaa
    48121 cataattatc tactgtgcta ttgccagtat tcaaagatgg aaagtcgaaa ttcttgtcat
    48181 ccgtataata aggcgtgtgg ttggttacgg aaagaaattt cgtgtaaaac ggctgttgta
    48241 gatgctcaag atattgggca gattctctga ataaatcttt atctaatatc ccataaccta
    48301 acgtttcgtc ggattcatca aaataagatc gatcaaagaa attgtcataa cctaagtttt
    48361 tatatacatg atctctattc caaaaactag ctacattccc atggaaaaca gcgcttgtat
    48421 agccttgctt ttgtccaagg atcgctggtg cggcttgaaa gacattgtct gacccaagtt
    48481 ctgtgaataa tgagccttga ggtaaaccaa atgtgccagt ttccaacata ttttcagcat
    48541 cacttgtctt tccctgtcct acttcatgaa agaaattgtc aaagctgatc gttgcttgat
    48601 tctggaaaat actatttaaa aacggtgtga cttcttgtcc gtctaccttc atattaatca
    48661 aaaactgctg gaaactttct aaatggagaa cgatcacatt tttcccttta gcgatcccaa
    48721 atgtttcggg atttggctct gcataatgtt tctttgtata atctaaaact tcatcaatcc
    48781 cattactgct tgcatgcgcg cgaacactgc tagtcattcc tgttttgatt ccgtcataaa
    48841 tagtatacgc atcgattcct agatatttga caatatatga acggtcaaat gttcgctgca
    48901 gcaattgtgg acggttggct tcgctcagcg ctagatttcc tgaaaaaata agccctgaaa
    48961 gacaggtaac agcgatagcc atcggtttgc cgacagggtt gcttttgata ggtattttct
    49021 tgaccttcaa ccaaaccagt agcccaatga acacagcgat atccagccag tagatgacat
    49081 catggggctt catcaaagaa aaggagcttc ctgacaatcc ttgcgacact ttcgaaaagc
    49141 ctaatacaga tttgactgta atgaaatctg tgaattcccg ataaaaaata atattcaagt
    49201 acaacaaaag cgtatttaaa atatcaatga tcaaaagaat agctaacgct ggctttggct
    49261 ttttaatata caaagaaagg ccaaaaaaca ataaggtagt cgcaattggg ttgatccaca
    49321 agataaagta ctggatcgta ccttccacac ctaatgaaaa atctgcatag taggcaatga
    49381 tcgtcttcag ccagaaaaag aaaacagctg tcaaaacgat tgctaaacga ttttggcaca
    49441 attttttaag ttgtgtcacg tatatcactt ctctctattc acattttttc ttattttgct
    49501 cctgaaaaat gaaaatttcc taaaaaagtt gttatcttaa gattttttta ttctttctaa
    49561 agattattcc gtccactttt cacagcataa aaccgctgcg atgtaagcga ttaaactaat
    49621 gaagagataa aagtcttgtg gtgaccgctt cactccacgg tattcaaaag ccagtttctc
    49681 ggtattcgta caaaaaaaga ggctgtgaca aaattcttgt cgcagctcct tatttcttga
    49741 tgcaggacag ctttttcaca acttcttcct taaacggtgt tctcctgcca actcctcggc
    49801 cacaagtcac aatatttata aaacatgaga agctgttttt tgaaattgtt ccttgtggct
    49861 cagagttaaa cggcaggctc aagacctctt gatacacggt gttcaatcag ctgaccctcg
    49921 gtattagatt atgtcaggac gctaatttta caacctcttg gtaaacggtg ttcaaaagct
    49981 tgcatctgcg gtaataagcc caaccaaacg aaaaatataa ggagctattt tttgaaattg
    50041 ctccttgtgg ctcagagtta aacggcaggc tcaagacctc ttgatacacg gtgttcaatc
    50101 agctgacctt cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttgccgtttg
    50161 tttctctaat actcaggtca aaacgctgat ttcacaacct ctgtttttca ttgtccatag
    50221 gattgatatt gtccttgtga tgactcattc gtaataattg aggcttgatt ttcttcactt
    50281 cccgttatcg tttgtccact gccagaatct gaaggacttg ttcctgtcga ctcgtttttt
    50341 tgagaagaga cagttgtttt cttgacttgt tcatttgtct ttttccattc cgctaaacga
    50401 tcggcgacca cttttttgtc tactttttca gaataagcgg tgatcacttt tccatttttc
    50461 aaacgggcta ctttgtcgcc atcatgagtc aaaagcaaaa cggtcaaatg cttgtcttta
    50521 aattgatatt gtctgagaga aatcgcacta agtacgtcat cgatattaat aaattgattt
    50581 tcttcttttc cttttggcaa ataaatgtcc aattcgcctt tttcgtaatt ggcagttatt
    50641 ttatactccg cccaccaata agttgagaat tcttttttga aattatctac tgattctttg
    50701 cttgctacga ttttttctgt ttctttctga gcaagatctg ctgtcatttt tcctgaaaat
    50761 gctgcggata aaataagcag taagaaaaaa ccgaataacc aaaagagaag aaacggtctt
    50821 tttttcctca tgctttcctc cactcctatt taattttgac tattctatta tatacaaaaa
    50881 atgaaataga aagacaaaaa agttgaaaaa gatcgtaaat aattgaactt ctttttcaca
    50941 aaatggtaag aatggagaat ttcacgcatt tgctctcaac tattctttct taagcctcaa
    51001 atccgttttt atctgatacg tctttgaacc aatgacccga ttttttgatt gttctttttc
    51061 catcttgtgc taagtctact gaaataaagc catatcgatt cttatatgca ttggtccacg
    51121 accagttatc catacatgtc cacatatgat agcctaaaca attggcacct tcttgaatgg
    51181 cttgatggac atatttcaga tgagattgga caaattcgat ccgataatca tcgtggatca
    51241 tgccatcttc tttgataaat cgtgcttcgt tttctacacc cataccgttt tcagaaataa
    51301 agcagtcgat atttccataa tgatctcgta cattgatcaa aatatcatag attccttgtt
    51361 catagatctc ccatccgcga taaggattca ttttacgacc aggcatttca taattgtcga
    51421 aataatcctc aggcattgga ccgtttttag tatcgattgg tgtttctttt gcttttaccc
    51481 ggcgtggctg gtaataattg atacctaaaa gatctactgt attttctttg ataaccgtca
    51541 aatcctctgc atggatcaca ggcatgagat caagttcttt tactatctca atcaattcac
    51601 ttggaaactc gccttttaca gctggatcaa ggaatgaacg attgaagaac gcatctgcta
    51661 tttgcgctgc tttaacatct tcagggtttg attcgtctct tggatagctt ggtgtcagat
    51721 tcaagatgat accaataaca ccaccttgct ccatttcatg gtaagatttg atggctaacg
    51781 ctgaagccaa cgcttcatga tagccaactt ggatcgcttt tttcatatct gactcttctg
    51841 gataatgcca tcgatataaa taacctgctt cgactggaac gattggttca ttatgagtaa
    51901 accatttttt tactttcgaa ccaaacaatt caaaacaact tttggcatat ttttcatagg
    51961 cttcaaccgt ttctcggttc aaccatccgc ctttttcttg cagatacatc ggcatatcga
    52021 aatgatacag attcacaaag ggttcgatac cgttttcaat caactcatca aaataacgat
    52081 gatagaaacg aacggcttct tcgttgattg ttccagattc atcaggtatc aaacggctcc
    52141 attggataga tgttcgaaat gaattatgcc cagtctgttt catcaactgt acatcctctt
    52201 gatacttcgt ataaacttgc gaggtttttt caggtcctac ttgatcaaag aacttttgcg
    52261 gttctttttt gtaccaataa tcaaaaatgt tctctccttt tccatcgcct gaaatccttc
    52321 cttctgtttg tgggccactt gctgcagaac cccaccaaaa atttgctgga aattgatatt
    52381 ttttcatcaa agcacctctt tttctttttt agttcgtttt agttgattcc atgtatgata
    52441 ttttccatca caatcacttt ttcattttct tcctcttctt ttttgattcg ttttaacagc
    52501 tgttctgctg ctcgttcccc gattttatct gttggtggcg tgatcgtgat tttcggaagg
    52561 atactcagat cgtttttatc taaataatca tagtgactga acgcaatatc cttcccgatt
    52621 ctgacacctt cttgattgaa acattcgatg gcaccaatcg acatattgta attgctgaca
    52681 aaaatagcag ttgccccttt ttctaataat gcttttgccc cgtaatagcc gctttttcta
    52741 gaatagtctc ctgtaaagac ctctaattgg atcgatggat cattttggac cgcttctttg
    52801 gctcctgcta aacgttctct tgctacgtag tctgtttgag tggcagcaat aaatccgatt
    52861 tttttatgtc cttgttcacc atgatgagcg atcacttttg ctacactttc tcgatcattc
    52921 actaatattg tatcaatacc tgctggtcct tctggacaat tcaatgcgat aactggaata
    52981 ctcatttttg tgagcatttc aaatccagac cactcttctt cggataagaa gacaatcagc
    53041 ccatcgatca catgcttcat caggtattca attttttgtt caattttttc tggctgatcg
    53101 gcaaacccgc ttaataataa gctataccca ttttcttcag ctactctttc gatccctgag
    53161 acaacttccg acccaaaacg gctggaaatc ccgtttatca aaagtccaat agagaagctt
    53221 cgattattct tcaacccttt agcaatgatg ttttctttat agtccaacgc tgaaatcgct
    53281 tctgctattt ttttcatgtt cttttccttc agttgctgac cattcaagta acgggaaact
    53341 gttcccactg aaacaccagc catcttagcc acatcacgga tcgatgccat acattctcac
    53401 tcctgccagt tacatttgat ttctctttct tgttgttcga ttatgatgac cgcattcttt
    53461 gcatagtgtt gcttgtcatc aatatccata taactaaagt cttcagtaga gcaacttcct
    53521 ctcactatta attatactta aacaagtatt tgaaccggtt catttttaat atagcatttt
    53581 tttaaaagat tgcaacactt ttttaaaacg ctttctgaaa gtggcggatt ttttgccttt
    53641 ttaaaatttt attctaaaat ttactctatt tgtgggtgtt ttgtgcgttt ttctcttcca
    53701 tccgtttgaa gttttacatt ccaatggtat aatttcttta tcctatcaaa tgggggaagt
    53761 attttgaaga aattaatcgt actatttatt ttgtctgcgg gacttttgac attgactggc
    53821 tgtgatttgt ttggcggctc tgaccaatcc tcggacgaaa caaccgattc ttctgtctta
    53881 aaagcggaaa aagcagatac caccaacagt gtatatacgc taaaagtacg taaagatatg
    53941 gatttatccg cgggacagtt gacatttaca gataaaaaaa tggaatggac acgcacgtat
    54001 cagacacaag gaactgattc ttctgaatca tctgaagaaa aaacagtgct gacagatatc
    54061 aagatcacta ccaaagatga cgaatatatt atttcaggaa aagaaaataa aaaagaaaca
    54121 acagtcatat ttacaaaaat cggtaattac cgtttgaagg atgaggatgg caacatctac
    54181 agtctatagt gccgtctgtt ggatcttctt ttgtttctcc ccttcttttc tgctatagta
    54241 aagaagcaag atgattgtaa aggagacgaa atggatgatc gatagtcctg attattgtac
    54301 atgtaataac aacaaaaata tccatacaga atttaatgac caaggaagct tgagcatatg
    54361 cgacaactgt cacaaactag tcaaagattc atttaaaaca tttgaatctt atcctgttca
    54421 aaattatgta aaaagtagaa gaagataaac aaatccaagc aaaactcact atggctgatt
    54481 tttatgaact tcaaactcag cttcttcctt tgatcaagct tcatcagtaa aacaaacagt
    54541 ggatcatttc agtttacaaa tcaaagagta aagatttatt tatttcaaat atttgaatat
    54601 aaaataacca aacgatagaa aggcttattc tacatcacgt agtaattttt ctttcccgtc
    54661 gtttggtttt ttatttttag cctaattctt gaccttttgc atgctggtta tccgtaaaat
    54721 attttccagc aggctttcct tccaattcag ctaatttttc ttggatctga cggatcacct
    54781 tttttgcatc ttctggattt tctacaaaat cgaatttatc cccatccact tgtattttag
    54841 gacatacatc aaaatcttca taccattgat tatagcgggt gttcaacgtt tcataatagg
    54901 tatataacgt ctcatcgctt tctagctgtt catagtcacg cccacgtttt ttgatacgtt
    54961 ctagcatcgt gtccaaagaa actttgatat ggaccatcaa atcaggccgt ttttttggag
    55021 caacatcatc taactcgttt agcatcgtat ctaataagct atcgtactgc tgtacttcga
    55081 tatccgttac ccgacctaaa tcagcgttta gatggaacaa caggctatct tcatagatgg
    55141 atcggtctag cacattgtca tcgttcacta aagcattttt cattgctaaa aatcgcttgt
    55201 tcaaaaagaa gatttgcaat aaaaaagcgt actgctcagg atttgaataa aagagcggca
    55261 atacttcgtt atcttcgaca ttttcataaa atggtttaga atcaatctct tttgcaagca
    55321 tatccgtcaa actgctctta cctgcaccaa tcgttcctga aatcaaaatc actgacatac
    55381 aacccttcct cttctataag tactcgccta cgtaagtttc aacaggcaat gtttcaaaat
    55441 catattcacg tacagcttgg tctgatttta aatacgtatg gagactttgt gtaatcatca
    55501 agttcgtagg taccgtctct tcttgtacaa tgatcatcgg ttttttcaac atagttgcca
    55561 cacctaattc gtaagccgtt cctggatcga ttgtttgatg ctcaaagtca aggatagcaa
    55621 caacaaattc tgcatttgtc agttcttcca tatctttttc gtatacttcc tgcgcccatc
    55681 cagcgctgaa tagttcataa ttgctttctt ggtgatgacg tggagagtag aaacttgtga
    55741 ctgttttgtt ttcctccaac gctttttcga tacgacttac tcgatcgatt tgctcctctg
    55801 aaaaaaatgg tcctgctaaa tatatttgac tcattatttt gcctccttca ataataactg
    55861 atttttaata gatactgctc gtaattcatt gaccagttcc aatggattgt tggaaaagat
    55921 tacttgatcc aaccattttt tatccataaa atcctctttt gcaaaagttt ctaataattg
    55981 ttgcaagccg ctgtaataac cgccaatatt caatattccg attggcttgt cgggcgtcag
    56041 accgattgct atccaagaaa gaagttgtga gaattcctcc aatgtaccta gacctccagg
    56101 gaaaacgagg acagcatctc ccttttcaaa taataatacc tttctttcat cgatcgtttc
    56161 tgtaggaata aatgtagtaa catcttttcc aggcaattca gtttcaaaaa gcccattcgg
    56221 atagatacct gtgacttttc cgttattttc cagtactgtt ttactaatca ctcccataat
    56281 cccggagtat gaaccaccgt aaaccagttc gatttcttct tgtgccatgt attttcctaa
    56341 cgtttgcgca ataaatttgt aactttcttt attaccaaaa cgggaaccgc aaaaaacagt
    56401 aagtttcata aaaaaacact ccctaactca aaagtctatc ttcattctac acgtgttttt
    56461 ttaaaataaa agactagatt ttgtagtttt ttagtggtat ataggataga cgccactata
    56521 tatagtattt agaaaaaaat catttttcag ccattttata gataaaacaa aaataaataa
    56581 cgtgttttca tcgatatgaa atgacttact tatagaagat actgggattt cgtcctatat
    56641 gccaataacg tgtattattt taaacaacaa atacttgttt cttttattaa cgaaaaaatc
    56701 attttgttct cgtgttatgt ttcactgata aatgatgttt ctctaaataa aaaagccgac
    56761 gaactaaacg atcaaaattt gatcattttt gttcatcagc ttctcctaaa aatctttttg
    56821 ttaacgataa atagctggat ttgtaaaaat atcacttgaa tcgtcactgc tggaagaaaa
    56881 ttcagtgata accgcacctg ttgcgcctgc ctggaactag tgtttgatat tgggctcgaa
    56941 cgtgtactga tctctagcat gaagaataat ttcttttttt actgtataat aactttcttt
    57001 cctttttgga atagtacagg aaagtttttt tgtttccttt ccttcgacat aaggtatacc
    57061 agaccctttc gacaacgaaa ggttctcatt tttccttcat cgtcatttca aggagggtgc
    57121 cgatgctctg gacagtttcg atcgctccta aaccaaaatc tgtatattcg attctttcta
    57181 actctgattc tttcatacca ttcctgtctc aaggtacatc tattgtactt ttttcttgta
    57241 atccattctg cctctcctaa ctaattgtca aatcatccca agatatgtct tcttcctctt
    57301 tttcttcttg gatgatttct gcattcggat ctactggttt tttcaataat aaaatggtta
    57361 ttcctgtgac aaaagaacca gctaacaatg caccaatgaa tgcccatggt ctggtcatcg
    57421 tagcgactgc aaacattccc gatgccggaa tacggctatc tgcgccccaa aacatgctta
    57481 atccgccacc tactgtccca ccgactcccg ttgctatgac attgcgtgcc aagtcgttca
    57541 atacgatagg gaaacatccc tctgtgatct gacagatccc cataggaaaa gcggtcttca
    57601 atgtatcgat ttcttgacga ttgagtatat ttttacgaat gattttccct aagaaataag
    57661 cgatcgtcaa gccgaatggg gttaccatcg aagctaaaat caatacagtg attggttcat
    57721 agattccttc tgaaaatcgt gccacacccc cttatccaga ataaatggta atccagaaac
    57781 agccgtgtat ctgcggtaat aagcctaacc aaacgaaaaa tatgagaagc tatttttgtt
    57841 tggctgttct tattacttga tgcagggcag ctttttcaca acctcttttt ttatttatgt
    57901 ttcataatca atatggtaag gatgcagctc cgtatggtag accgcctccg aatattcaat
    57961 catttcccca atttgcgtag acgatttccg tatccgtttg atgccgatct gtgcgtctgt
    58021 tttcagaatt ccttgttctt cttctgttaa aaatactgcc gagaaatcat cagaaaatga
    58081 gtcaatagta tatccttttt tcgtcagcaa acgatacaaa gattctttgc caaattcttc
    58141 tctgctgaat tgcatcattt cttgtggaag ataatgaaca aaataaatat aaggctgatt
    58201 gttcaaataa tataagcgct taaaacaaac agcttgctca ccgaaaaagg aaaacaaagg
    58261 atcttccttc tttatatgga ccaattgcaa atccagcgtt tctttccgga cttcatatcg
    58321 ggagttctcc aagatttgcg taaagcttgc cgctttggat aatcgattgt aaggacgatt
    58381 gcttagaacc gtcgtcccac gaccactttt ctttgcgaca tattcatctg atgccagcag
    58441 ttcgattgcc tttcggacag tgattttgct gacttgaaac agttcttcta attcactttc
    58501 tgtcggcaac atcgaaccga ctggatattt tcctgagaaa atatcttctt taattttatc
    58561 tgcgacttcc aagtatagta cacgtgtcct tttcataacg tcaccctttg ctttactatt
    58621 actaaaagaa tagcacataa aaaataaaaa aagaacacaa atcacatgtg agaagtgtgt
    58681 tctttttcat tcagctgctt taattacaag tttacgccat ttgaggcaat tacttcttta
    58741 taccaatcaa aagatttttt ctttgatcga ttcagtgtcc catttccttc atcgtctaga
    58801 tccacataga taaagccgta acgtttactc atttctcctg ttgatgcact gacaagatcg
    58861 atacatcccc aaggcgtata gcccatcaaa tctacaccgt ctgctactgc attagccatc
    58921 gcttcgatat gacgacgtaa ataatcgatc cgataatcat caataatcgt gccatcctct
    58981 tccatatgat caatggctcc aagaccgttt tcaacaatga ataatggttt ctggtaacga
    59041 ttgtataatt cattcaatgc gattctcagc ccttctggat cgatctgcca gccccattca
    59101 cttgcctcaa gaaacggatt ttttactcct cccagcaagt tcccttctga agttgctgct
    59161 tgtggatcag tctcattgat tgccgtagac atataataac taaatccgat gtagtccact
    59221 ggatattctt ttagcaactg gaagtctttt tccgtttgct ctaatttttc cggatcgact
    59281 ccatattttt tatgggtacg cgctgtgtat gcagggtatt ctccacgtac ttggacatcc
    59341 gtgcagaaaa aattgaattc ttggttttgg atcattgttg ctgcctgatt gactggattg
    59401 gcatcgatgc tgtaagttgt tgcatagata atcatgcagc cgatttggat atccgaacgc
    59461 aattcgtggc cgatttttac ggctttgcta cttgcaacga attgattatg ccatgcttgg
    59521 aaaatatttt ggtactctcc tgctccattg ctttttacta atccttgact taaagctgga
    59581 aagtgaaagg ccgaattgat ttcattgaaa gtcatccaat atttgacttt actgctgtat
    59641 ctctctaata ctgtctgagc aaatcgttca tagaagtcga tcagttttcg atttttccag
    59701 ccaccgtatt cttttgccaa atgaagaggc atttcgtaat gagaaatcgt gatcacaggt
    59761 tcaatatcat attttaagca ctcatcaatc agctgatcat aaaattctaa tcccgcttcg
    59821 ttaggagtac cttcgtctcc atttggaaaa attcgtgtcc aggcaatcga aaaacgataa
    59881 catttgaatc ccatttccgc aaacaaggca agatcttctt tgaaacgatc gtaatgatcg
    59941 attcctcgat gattcgggta aatatatttt tcttgatcaa tcgtccagtc aaattcttca
    60001 ctgccgataa tcgcaaagcg ctgcttacct ccaggcatag catctgcaac ggatagtcct
    60061 tttccgtctc gatcataagc cccttctaat tgatttggca gcagttgctc caccccataa
    60121 aaatttttct gaaaaacgtg attgcatcct gatttcctcc ttattttaca attgccagaa
    60181 catcttcgtt tgcaataatc tctttttggt ctaattcaag tatatcggca aatgcatcag
    60241 tattcgtaat gacaactgga gtgattacgc tatagccagc tgctctaatt gcttcgatgt
    60301 caaaacgaat caataaatct cctgctttga cgagatcccc ttgtttgact aagatctcaa
    60361 agccattccc atttaattct actgtatcca tcccgatatg aatcaaaatc tccgctccgt
    60421 cagtcgttgt gatccctaca gcatgtccag ttggaaaaat agtcgtgatc tctccgtctg
    60481 caggtgcaac tagttctcct acttctggat caatagcgat accttttccc atcacgccag
    60541 aagaaaaaac ttggtctggt acttcactca atggcagtac tttacccgtt aaaggacttt
    60601 ttaaggtatg ccgtgctgaa gtaatcggtt ctcctgcatt cgcatgtttg ttttctaatt
    60661 gattgtcttg tgtttgttcg tcaaatccta aaatcaatgt acctacgaat gcaagaacaa
    60721 aagcaattcc tgtagctatt actgctactg tcacatttga ctctacacca tccaccgtat
    60781 taatgaaagt cggaatcgtc aataagctga ccaaactgct ggagaaagct tttactccgg
    60841 aaaatccgat aatagctcca ccaatacctc cagaaataca agcggcaatg aatggtttct
    60901 tcaaaggtaa tgtcacacca tacacagttg gttcagtgat tccaaataac gaagtcactg
    60961 tagaagaaat ccctaatgct cgaagtttcg tatcttttgt tcgcaatgct acagctaaag
    61021 cagccccacc ttgtgccaag atggctggaa gaagcattgg catcaataca tcaaacccat
    61081 attgttcgat attcaaaaac atgatcggta cgaatcccca atgcatgccg aacatcacga
    61141 atacttgcca taaacttccc atgattagac ctgctacgat tggactaaat ccataaatcg
    61201 agttgaagag accgcctaaa gcattaccgg caaccgtccc gattggtcct aaagcaagaa
    61261 atgttaatgg aaccatcact actaaaacga caagcggaac taaaatcatt tgcagaaatt
    61321 gcggaatcac tttttttacg aatggctcta atttactttg aacccatacg gctagaatga
    61381 ttggtatgac agaagaagta taaccagatg gtgaaagaat cactgggatc ccaaagaaac
    61441 tgatagcttc tcccgcacca gcaactgctg tgatagctgg atacacaagt gccatagcaa
    61501 ttgctactgc taaaaactgg ttggctttga actttttagc tgctgtaaaa gcaagcatga
    61561 caggtaagaa ggtaaagaca ccatctgctg cagcaaacaa tatttgataa gtaccgctat
    61621 cagctgtcag ccagcccatc accgttgcca atgataagaa tcctttcaat accccggcgg
    61681 ctgccatcgc ccctagaaaa ggtgtaaata tactagagat aatatcgatc agacgattca
    61741 aaatattttt ggactcttct tttccatcct ccgaaactgc aagaccttcc tcatccacga
    61801 tcgattgata aacatctgct acattactgc caatcactac ttgatactga ccgccacttt
    61861 gtacgacttg gatcacgtcc gggtcttctt ttaacttttg cgtatctgct aaagattcat
    61921 cttttaatct gaatcgcaac cgcgtagcac aatgtactaa acttttgaca ttcttttgtc
    61981 ctcctaccgc ttcccataca cgacgaccaa ctgcttgatt atccattgtt ttttccttct
    62041 ttctttttta tttaaaaaat aaaaacccag attgaaaaaa acagtcacaa acattcgtga
    62101 acctattttt tcaatccagg ttttgcctgc catacagtaa caatccttat gattggatgc
    62161 tttttttctc acttactact ctttgaatat gaatcgttaa ataaatctgc tctgcgatcc
    62221 ccatttcctg tttttgcgtt tgtcgaagat actcattgat ccgttcgaca caatgaaacg
    62281 cttttggata ctttccttga actaatgcgt agagaaattc atcttgctcg tcagatcctt
    62341 cccctttgag ataacgctgg gcaaaaaact gcagatgagt aatgatacgc tgataattca
    62401 aagattcttc atcgaacacg atgccgaaga atttactgat gatactcagt atatctctta
    62461 ccattgtggt agcggtcatc gtcacttgca tgtcttcgtt tccttgttgg ctattcacaa
    62521 aatgaaaggc aataaaaccg gcttcatcct cagaaagttc cacacccgtc ttttgtttca
    62581 cgaacaaaag agcctctttc gctgcttgat attctttcgg ataaaatttt tttgtttcaa
    62641 ataataatgg attaggcagt tggatatttt cttttgctcg tgtgatcgca taatgaagat
    62701 gatcggtcaa tgtcagataa atattaggcg aaaattcaac ttttagttta tcttcagcca
    62761 gttcgactac ttgtttgacc cattcgatct cctctgccgg aatatcagcc atcagctgct
    62821 ggaattggtt tttagcaaaa gaatctctta aacaaattct ttttggaccg cttctggcga
    62881 aatctcgtcc ccaatctttt tttgaaaagc tagtcctttt cccatacaaa cgacttcttc
    62941 cccgaatcca tttttcgaaa tgacgacatt gttattcaaa attttatcaa ttttcatttt
    63001 gcttcgccct ctcaagaaaa ataaaaaaac ctagaattcg cctactgttt cttagctgaa
    63061 ttctggtttt gcctgccgta cagtaacaat ccatttctta ttcaaaatca tcataccatc
    63121 gaatttttat ttatgcaagc cttttcatat aaaaaataaa aaaactggaa cacaagtcta
    63181 tctagaaaac aaccaaatca gagatgcacc tctttgcgtt tctctttttt tcagcaaatt
    63241 ggtttttcct tatcgattca tatcctttgg ctgtttttaa tctgtaacga cttatgtccc
    63301 agtatcctaa aatgtttttg tctctagatt gaaagcagat ctcatatcat ctgtcgcatc
    63361 ttttatcgat gtaacacttt ccagttctcc ttgtacaact agtcgcgtga cggcgtccat
    63421 gtcgccacaa gtaattagtg tgacaatttc ttttccctcg acttcattca gtaattgggt
    63481 atctgtagga gcaacttttt ctttaaaaaa tgttttgtat gtatacacat tttctaaatc
    63541 tgtcaaatag atcttggcac ccatctctaa attttctagc ggtgtaaaca gcaattcagg
    63601 gttcgttgca cgatggcttg ctaaggcata atttcctttt cccatttctt gatctggaga
    63661 taatgttcct gctccgtaaa gtagtgacgt attatccaag cctttgaaaa ccggtaaatt
    63721 gattgaaact gaagggactg cgatactagc aatcactggt agatctgttc ctctcatttg
    63781 cgacctcatg accccttctg tcgtcattgg ttctaccgca tcaaagtcaa aactgacatc
    63841 tttatcgtta ttctttttca gatcttcttt tgttacattc gctatagcat atttatctcc
    63901 tgtctctctg acaaaataat ccttgatctg ttcattgaaa atcaaagcta gtcctactaa
    63961 taacaagagg aacaagagga tattgactag ccatcttttt gcttttcctt tttttttcat
    64021 tttctctccc tccagactca ttttactgtt tttcttttgc tctttccaac agccgaatga
    64081 cacatttcta caactctgtg tatttttttc gtacacctgc gcttttttct acaggatatt
    64141 tcaaattatt tttgatcaat ttttcttcaa tgatctcatc tagatccagg tgaaggttgt
    64201 ctgccatcat gtatgaatag atcaatacat ctgccagttc ttctttgatt cgttctaatt
    64261 gtgtttcttt tacttcttcc ggcgttttcc attgaaaaag ttctaacaat tcagatgctt
    64321 ccaaagaaat agagatagcc aaatcttttt cgttatgaaa ttgtcgccaa ttacgttcat
    64381 ctctaaactg gttgactttt tccatactat tcatttgctt gccttcttcc aatcacttct
    64441 tacttgatta atcataccat ttttttacat aaaaaataga tgatgctttt aaaaaaactc
    64501 ctgttttctt ttatttaaaa taaatgtcat agaaaatcaa taatttaggt agccaccatg
    64561 tgtatgcagt agcgtgtctt cttcccttga ggctttttgt ttttcgatac gttcttcttc
    64621 ccaaacagac aacgctacta gaatctctct taatgatttt ccttcttcgg tgagcgagta
    64681 ctctacttta ggcgggactt ggttataggc ttttcgatgg atactttcat cttgttctaa
    64741 ctctcttaac tgctgggtca gcattttttt tgtgatcgta gggatttgct tgcttctcca
    64801 cgcctaaaat aagcgatatt gctcttccct ttatctggtg taagcaaagc agttagcatt
    64861 ttgacgatcg tgggttccgc ttttcacttc ttatctactt agtatcatga agtatacttt
    64921 cgtactaata ctaagtagcg gaagtgtcaa ctactttgtt taactacata gcaaaagaaa
    64981 cagaagggtg acaacggtca tcacgcttct gtttcttttg aatatgctgt gttgttgtct
    65041 ctatctccgt gtagactttc ctcaaactta tcctttgaca gtaagtcagt aggctgattt
    65101 gctctttcta gatgccagat acatttctac aaaaaaatag tgattctgtt ttgaaaattc
    65161 gatttttagt tctgcatttt cgtaaacatc caacattttt ttcgcactgt atagacctaa
    65221 cccgccattt tttttagagg tttttcctct tttgaccatc tccgatagcg tcaaattcgt
    65281 tggatttgcc ttgttcgcta tactaaaacg tgatccctct ttttcttcca gcagattgat
    65341 cgtaatcgga ctctgatcgg ctacacgatg atcgaatgcg ttagaaataa aaatagataa
    65401 acagcgaata aaaacaacca gatcaatcgg gattgttttc acttcgacag gaataactac
    65461 ttggatcggg attttctccg attctgcttt ttctagaaat tttaaaaaga cacccctgac
    65521 agctggggat acaatatttg ttagctgttg tatttgcggt ttttcaaaaa tagctgcaga
    65581 atgatcttct aatatttcta aaaattccaa cgtttctttt ttattttcct gaagagtaat
    65641 ttttaatgaa aacagtagac ttttataatc atgtttgaat tcctctagat gatggtaata
    65701 ttcttcattt atttgataca gttgaagcga ttcctgatgt tgtctttctt ttacttggaa
    65761 actgatcaac ataatggaaa aaaacaaaga aaaaaaactg atgactatcg acaaaagaga
    65821 tagaagcaga taattagatg agcggaagtg aacacttccc aataccaagt aaatcacgcc
    65881 ccagcttaat aaaatacaaa tacctccaaa atagtgttca gttggataag taaaaagcaa
    65941 gttgagaaat ctcgtctgtt tgtctatact ttttactaat agatagaaaa taaatgcgat
    66001 aagtagtgca aaaaaacttg ctgttccaag atgtctcttt cctaaataat ccatcagatc
    66061 aaaaaccaga aaaaagctga gtccagtgat agcaaaaaaa agattactga tcaaacagct
    66121 gataaacagg tttttcgtag taaaataaaa aagaaacatc aataataagc caactaggta
    66181 aggaaagctc actttaggga taggaagtaa aagtgtcacc accatcaaag ctatacaacc
    66241 aaagctgttt tttactagca gttgtttcga aaagaataaa tagataccta aatctaaaat
    66301 caaagtaaag gtcaaataaa gtgtcactgt tgcgaccatc ttattcctcc attgttttgt
    66361 ttcaaaatgt acacatattt ttttaatagg agcctgcata tgaaaaagta ttttatcata
    66421 gaagataacc agtttcacag cgaatggatc atcagagaat tggtcaatca tcatatcgag
    66481 aatatcgtgc agctcacttc tatctctcaa atcaatcagt tgatccagtt gggcactatt
    66541 gataatcacg atgttttctt tatcgatatc gacttgaagc aatcactcac aggtattgat
    66601 gtcgccgaac aaatacgtaa aaaaaatgca catagtaata ttgttttttt caccgcttat
    66661 acgaattttg cagtagagat catcaatcgg aaaatccttc cgattggata tatcagaaaa
    66721 gacaggaatt tatctgaaca aattcgtcaa gtgctagaac agatcaattg gaaagaacag
    66781 cagatcgtaa atgtcgataa aatctttatt gatcaaaaag gtggaagtct cgtcctgtat
    66841 cctcgggaaa ttttatatat tgaaagtatc aaaggtttga aaaaccaagt tatggtcaaa
    66901 acaactacag aagataaatt agtgaatact tctttaaaac aattgaagac agagttagaa
    66961 aagtatgctt actttttact tttaaaatct tactgtatca acttatcgca attgcagaaa
    67021 attgattctg ctcattatgt gttagaattt ttcaacggtg actccttact cgttggtcga
    67081 aagatctttg aaaagacaaa ggaacgtttc catgacttcc aaaaaactgc ttcgagttga
    67141 tgaataagag ctgagacgta agcatagcag atttcaggga gtgggccttg aatcggctcc
    67201 actccctgaa atcgttgata tgattttacg cttcctcttc tgtaggagca tctgttaacg
    67261 accatgtgaa tgttgaaacg tagttgtcta cagcataatt ggatacagga acaaataatt
    67321 ccactgattg tctcccttgt tccacattct ctcctaatga ataaatccat gtgccaatcc
    67381 cttcatttgc tcctgcagtt actagatcta ctgcctgatc tgctgggatt tcgattcctt
    67441 cagcgccagt tccagaaacg gtagatggca ttccactgct attagttgcg ctatttcgaa
    67501 tcacggcgtt tttgaatttc acctttgaac cagttagttt attcgtatca gatgttgtac
    67561 caataaattc tgttcgtttg actgataatt tccaaccggc ataatttccg cttttatccg
    67621 ttacttgtac gaaattctgt acttgtgttt gtgctccagt actgtccgtt ccgctttgta
    67681 atgcagcata tactgttttt gctgtaccta acttgattgt tccaaaatca agatctggag
    67741 cttggtcaat cgtcagtaat ccggatgttc cctgatttgg ttcgtcaggt gtaaaaggag
    67801 tatcaggatc atttggatca acaggaggaa ctggaacaac gtcttcagga tttgcagcat
    67861 ctggtttggt cacagaaatc gttccttctg tagtggctga gctcttattc tcagcaaaaa
    67921 cactttgtgt acataataat agacttccag ctagaacggt acttaatgca attgtttttt
    67981 tcatttcttt ttccttcttt cttttaaaat aaataatcca gcaaataagc caataagaat
    68041 gactccaaca agtatcagcc atcgccagtc aaatgtttct ggctgatttt ttaaatcaat
    68101 atccttttca ttcaattggt ccgctgcatc atcagttatt tcaaaatcgg tatggagatt
    68161 ccagcgtttt tctttccaag cacccttcac aaccgcttga taatgtcccg gagctaattt
    68221 ttttccttct aatgggacaa gtaaatcaaa atttgtattg ggtgctacat ctattttttc
    68281 tttttttatt gaaaggtaag gctcttttgt ttcttttttg tagatttcaa ccgatgtagt
    68341 caagccgaac atataagaag catttggatt ttgaagattc gccttaatca catttcttcc
    68401 atcgctttga tccgcataag ctttttttaa tttcaaatct ggggaagact ctttttcgct
    68461 atttcaaatc aagattgctt tcacttgaga aaactgattg acgacaccaa ctgtactttt
    68521 gttagaaacg ttctcttttt tttcttgaaa cgtgatccct cctgcgacca caccagccag
    68581 ctctttttct ggcgctttca gtgaaagtgt ctcagtgacc gcactttgag gaggaacagt
    68641 tatttctccc actgtttttg ctaagttttt catatcataa cttaatgttt catcaaattt
    68701 actttttgat tctccatatt cgatcacacc gtttgaattc gtcgtagcgg agtggatcaa
    68761 tgtctcaact gttactgatt tatctgttcg gttaaagacc gtgtagggga tttcctgtgt
    68821 tttcccaggc tccatcctta catttatata tgttttgttc ttatcaatct gattagccgg
    68881 taattcaaaa tctaccgcaa aattgaattc ggaggcatgg acaggtgtct gccaaaggat
    68941 gaatccaagg agaaggatca taagtaaaga gcagttgttt cgatgacttt tattccatat
    69001 tcgattcatc aatcatcctc cttgatcttt attctgtcgg cgcatctgct aatgtccatg
    69061 ttatctctgc tgagtaatta ccagctatct gattttcttt ggttaagaca agtttaaacg
    69121 cccgaccgtt atttaaatat tctgaataat ctgcttgcac attcgttgaa ttttgtcctc
    69181 tgacaatttc cagttcttct tcattcacta attgatactc ctctcctttc ttgaaatata
    69241 ggacatcctg catagaaaat cctgcatcat ttgtgaaagg ctgagataat tttatcgtta
    69301 agatccacgg atttttcgtt tctcgctgat cataaatcca taatttttcc tgtatatcca
    69361 tttggccaaa tgcttcttgt gtcaaaccag ttgctttgat ctgaccaaaa tcgagtttgg
    69421 aaggggcaag aaatgagaga ccaccttcta ctacgatctt cgtagcaggt gcaaaaggcg
    69481 gggcatcatg ataaacaact ggcgtatcac ttggattgtg attcccaatt tcatcgttgg
    69541 tacttggctt gttctgcaca cccttagcag tagcttctcc tgcttggtcg tttaatacaa
    69601 tttctaatac atctcctgca aaaagttgat tttctgggat agaaagaaca aattcccctg
    69661 tatcatcaat agttgtttct gacaaaacag cttgattttt tttcaatgaa accaaggctc
    69721 ctgcttcacc tgtacctgtg atcgtgcgag aagctgcatt gatcaatgtg gtacttaaat
    69781 tagcaggttc aggaggaatc acatcgactg tcgttttggc agagtccagt tctgtcactt
    69841 cttggccacc tcttactttt ttagcagcaa caacttgcac ttgatcctcc gtttttaatc
    69901 tctcatcatt gggtacttga acttcgaaca agccgccttg ttcgccttct ccccatgggt
    69961 tatatcctgc cccttcattt tcatctgttt gtccttgcgt gagagcagta atttctacag
    70021 atgatttcgt cgtatctgcg taagtaatac gtaaagtcac ttctacttcg cctgtccaag
    70081 catctcttgg ctttgcctcg acaccttcgg gaacaacgac atgcccatag atttttttat
    70141 ctgcattcgt tggcactctt aaggattcaa tcatcgggag ctgattattg gcactgattc
    70201 gattataatt tttcattccg gcacctgtct gagcaaattc atttgttaaa cctgcactag
    70261 ggcttgatac gaaattgcct aagtcggtcc cattgatcga taagtctgtc atatcagaaa
    70321 aataatccgg gtctttttca aagttatcga atgttgcgcc tgtttttcgc cataaagcga
    70381 tttctgaatg ggcgatcttt aaagaagaat ctccatttcc ttggaatacc cagccgccta
    70441 tgccattggt ctcgcttcca atccgtttgt tttggaaatc aaaataggta ggagattcta
    70501 agtccacatt caacacatcc ccactgatga tgccggtctt atcttcccct gttttcccga
    70561 ccatgactaa ataagttttt tcacctgccg taaaatttaa atcaatatct ccagttgtat
    70621 ctacagttgc tccggaatct gcgcgtatat cgatatttga tttttctcca gtgactgtaa
    70681 aatcagctga acctggactt tctagaaaac cagaagcgtc ataaaattgg atcgcttgat
    70741 ttccttgatt gagtctgttc acgtaagatt tgccatcacc tgtatttctt accctcaatg
    70801 agcctccatt ggttactgtc agcttttgcg taccattctc aaaacgaact gcgctggaac
    70861 gcccactctg cttatcgatg tcgataactg atccggctcc ttctacgatc aaagaaaggc
    70921 cttttcctac aaaacgcatc ccattgttcc cgggttgatc gtcatctcca gccattttga
    70981 ccgagatttg tccaccactt gatacatgga tttgactaga atctccttgc aagcgaaatc
    71041 cgcccgtagt tgctgtattg atggtgattt tcccaccatt cgatacagtg actttcgatc
    71101 ctgaacctct catttggatg attccgcgat tgttgtcatt ggtaatattg atctttgtat
    71161 ttaccgaaaa ttcgcttccc gaaccactga cttcaaacat gacattacca ggtagcgtat
    71221 cgactgcctc tccttcatcg ctaacgccat ctgcccgatc ataatcaaga gagacctttg
    71281 aaccgcttaa gatatggatt cctggcgctg tttttccact accagtctca tctcctgaat
    71341 ctagaaaacc gtagaatttc cctagatacg gtccataaag ttgactacca ttgatcacat
    71401 tcaattgata gcttctacaa aaataggctt tacccggagc ggcattcagt ccttccttca
    71461 ctggttggac atccaacaca ccggaaacac catctaatgt gacagttgca cgaggagcgt
    71521 aaatcagtcc taatttggac ccatcataca aatcaagtgt cccggtaaat tttatttctc
    71581 ccgtaaaatg atatctgctt ccccaaaaat cggtcatata agcaatgata atggcatttc
    71641 catcgatatt tggtgtcaat ccacctggat gtgcagctgt tcctttaaaa ttctggaact
    71701 cgatcgactg aggtatctca ttgatataaa tatggtgtgt gccgaaattg tgagcgaatc
    71761 caccaaaatc aataacgata tctcgtttga tctctaattc cctgtctaaa gtcaaaggct
    71821 gaatcagtcg gatcttagtt actgattcgt ctgcgagaag ctgcgccagt tcttctgttg
    71881 tggcagcttc gctgtaccca tccgctgaaa cagctcttgc cagtgccgct tcactgctat
    71941 cagacgtttg ttcagctact tctgaggtct cacttgtctt attttcttct tgccttttat
    72001 tagtagaagc ctcactttga gattctgtag tttcagaagt aatcgattct tctgaaaaag
    72061 tagtcttgtc aaaactttga ttctctgatt gcgttgattc gtttgttttc tctacatcgg
    72121 caaaaacgga tgtcaccatc aagagaggga agacaaacaa aatcgacgca atcagctttt
    72181 ttacacattg attcattctc caccatcctc tctgacgttt tgacaatttt attttatcgt
    72241 tttaatctat ttccaattgt actttcatat ttaaaatatg tatttttatg gaaaaatttt
    72301 tctattaggt gtaaatttct tttttgtaca aaaaaaaggc tgtgacaaaa gtcttgtcac
    72361 agtcccttat cccgaacaag cggtgttctc ccgccaactc ctcggtcaca acctccattt
    72421 taacaataaa cctgtaaatg tgagggcaat actttgattg tcacaggtaa tttatcccct
    72481 tcatctccat caacattcgt cgtcaattct tcctcatcag ctaatgacac aactaattgc
    72541 tcacaagtaa ggtaggctag atttttcgta gattcatcta ctccttttaa taggtctggc
    72601 aatgttttaa gcgtatcgat caaagaagaa tcttttaaat aaaccaaatg gagcttacca
    72661 tcatccactt ttgcatttgg aagtaatgtt tcaaaaccgc cgactgagtt agttagtcct
    72721 atcagcaagg tactgctctc aatttcttcc ttctttccat caacttctac gtgaaacgag
    72781 taggattgtg tggaagctaa ctgtttgatt cctgacatga aataagctag ttttccaaat
    72841 ttcgtcttct tctccgcatc tacatcattg attgattcag ggatagagcc aattgcgacg
    72901 acattcataa aatagtcgtc atttattttt ccaatatcca atggcttgac tgattcaatc
    72961 gaaaaatgat tgatcgcttc ctcaggttct agcggtatcc ctaatgctcg agccaagtca
    73021 ttcaccgtac ccaatgggaa aaatccgaaa tttggccgat gttcttgttc agcgattcca
    73081 ctgattcctt cgttgactgt tccatctccg cccatgacaa acacactatg atacccttcc
    73141 gtagccgctt cgcgagtaaa gttttttgca tcccctgctt tttttgtatg caagacgacc
    73201 acttcatcaa acaccgattc caattttgct atcgctaatt gctcaaattc ctttgcttgt
    73261 tcaccgcctg aactggggtt taccactaat aaaacttttt tcatcacttt ctttcccttc
    73321 tgattgattt ctttaatata acgatagcat aaagaaaaaa attaggctgt gatgaagtac
    73381 tgttcatgaa acattcattt attttttgac aagataaaac atccatacta tgaaactgag
    73441 gaaaattaaa acaatgatat aggaaataaa agaaaatgat aggcattgta tacctaataa
    73501 agtaaaaatc ttaggtggca gataaaaaca caaaaatagc aagagaatgt aatagcgttt
    73561 cttccacttt ttgttatcag accttatagc gatcagagga ataccaaatg cataactgaa
    73621 aaactcttga tgtactgtta atatgtcacg gccttgaata ataaatgcga caatccccgc
    73681 tataattagt gtgcctaaca ccaaaacgga aaattgatga atatatttta tatacaaatg
    73741 atccattgta cttcctgcct ttttatttgt gagaaaaaca aatccgtata cgtgaataac
    73801 ttctagaaat aaaagaaatt tgcaaaacca ctccatttat ctacttct
//
LOCUS       DADVXV010000003        68619 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.003, whole genome shotgun sequence.
ACCESSION   DADVXV010000003 DADVXV010000000
VERSION     DADVXV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 68619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.003"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(122..499)
                     /locus_tag="KB969_000141"
     CDS             complement(122..499)
                     /locus_tag="KB969_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868161.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            755..1483
                     /locus_tag="KB969_000142"
     CDS             755..1483
                     /locus_tag="KB969_000142"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBB6868162.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1483..1737
                     /gene="purS"
                     /locus_tag="KB969_000143"
     CDS             1483..1737
                     /gene="purS"
                     /locus_tag="KB969_000143"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBB6868163.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1739..2410
                     /gene="purQ"
                     /locus_tag="KB969_000144"
     CDS             1739..2410
                     /gene="purQ"
                     /locus_tag="KB969_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBB6868164.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2411..4633
                     /gene="purL"
                     /locus_tag="KB969_000145"
     CDS             2411..4633
                     /gene="purL"
                     /locus_tag="KB969_000145"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBB6868165.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4618..6057
                     /locus_tag="KB969_000146"
     CDS             4618..6057
                     /locus_tag="KB969_000146"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBB6868166.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6080..7132
                     /locus_tag="KB969_000147"
     CDS             6080..7132
                     /locus_tag="KB969_000147"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBB6868167.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7129..7707
                     /gene="purN"
                     /locus_tag="KB969_000148"
     CDS             7129..7707
                     /gene="purN"
                     /locus_tag="KB969_000148"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBB6868168.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7704..9239
                     /gene="purH"
                     /locus_tag="KB969_000149"
     CDS             7704..9239
                     /gene="purH"
                     /locus_tag="KB969_000149"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBB6868169.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9255..10529
                     /gene="purD"
                     /locus_tag="KB969_000150"
     CDS             9255..10529
                     /gene="purD"
                     /locus_tag="KB969_000150"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBB6868170.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10651..11565
                     /locus_tag="KB969_000151"
     CDS             10651..11565
                     /locus_tag="KB969_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6868171.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11698..13263)
                     /locus_tag="KB969_000152"
     CDS             complement(11698..13263)
                     /locus_tag="KB969_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6868172.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13256..14707)
                     /locus_tag="KB969_000153"
     CDS             complement(13256..14707)
                     /locus_tag="KB969_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6868173.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14721..15737)
                     /locus_tag="KB969_000154"
     CDS             complement(14721..15737)
                     /locus_tag="KB969_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6868174.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15957..17045
                     /locus_tag="KB969_000155"
     CDS             15957..17045
                     /locus_tag="KB969_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBB6868175.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17099..18625
                     /locus_tag="KB969_000156"
     CDS             17099..18625
                     /locus_tag="KB969_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBB6868176.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18627..19832
                     /locus_tag="KB969_000157"
     CDS             18627..19832
                     /locus_tag="KB969_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868177.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20089..21066
                     /gene="guaC"
                     /locus_tag="KB969_000158"
     CDS             20089..21066
                     /gene="guaC"
                     /locus_tag="KB969_000158"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBB6868178.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21330..22754
                     /locus_tag="KB969_000159"
     CDS             21330..22754
                     /locus_tag="KB969_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6868179.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23215..24324
                     /gene="pdhA"
                     /locus_tag="KB969_000160"
     CDS             23215..24324
                     /gene="pdhA"
                     /locus_tag="KB969_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBB6868180.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24327..25304
                     /locus_tag="KB969_000161"
     CDS             24327..25304
                     /locus_tag="KB969_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBB6868181.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25329..26972
                     /locus_tag="KB969_000162"
     CDS             25329..26972
                     /locus_tag="KB969_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBB6868182.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26980..28386
                     /gene="lpdA"
                     /locus_tag="KB969_000163"
     CDS             26980..28386
                     /gene="lpdA"
                     /locus_tag="KB969_000163"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBB6868183.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28548..28823
                     /locus_tag="KB969_000164"
     CDS             28548..28823
                     /locus_tag="KB969_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBB6868184.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28829..29596
                     /locus_tag="KB969_000165"
     CDS             28829..29596
                     /locus_tag="KB969_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBB6868185.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29764..31593
                     /gene="typA"
                     /locus_tag="KB969_000166"
     CDS             29764..31593
                     /gene="typA"
                     /locus_tag="KB969_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBB6868186.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31854..33626
                     /gene="recQ"
                     /locus_tag="KB969_000167"
     CDS             31854..33626
                     /gene="recQ"
                     /locus_tag="KB969_000167"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBB6868187.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33740..34042
                     /locus_tag="KB969_000168"
     CDS             33740..34042
                     /locus_tag="KB969_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBB6868188.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34045..35208
                     /locus_tag="KB969_000169"
     CDS             34045..35208
                     /locus_tag="KB969_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6868189.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35234..38662
                     /locus_tag="KB969_000170"
     CDS             35234..38662
                     /locus_tag="KB969_000170"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBB6868190.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38683..39807
                     /locus_tag="KB969_000171"
     CDS             38683..39807
                     /locus_tag="KB969_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868191.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39797..40234
                     /locus_tag="KB969_000172"
     CDS             39797..40234
                     /locus_tag="KB969_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6868192.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40218..40556
                     /locus_tag="KB969_000173"
     CDS             40218..40556
                     /locus_tag="KB969_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBB6868193.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40675..41235
                     /gene="rsmD"
                     /locus_tag="KB969_000174"
     CDS             40675..41235
                     /gene="rsmD"
                     /locus_tag="KB969_000174"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBB6868194.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41232..41723
                     /gene="coaD"
                     /locus_tag="KB969_000175"
     CDS             41232..41723
                     /gene="coaD"
                     /locus_tag="KB969_000175"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBB6868195.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41713..42756
                     /locus_tag="KB969_000176"
     CDS             41713..42756
                     /locus_tag="KB969_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBB6868196.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42915..43643
                     /locus_tag="KB969_000177"
     CDS             42915..43643
                     /locus_tag="KB969_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBB6868197.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43759..44004
                     /locus_tag="KB969_000178"
     CDS             43759..44004
                     /locus_tag="KB969_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6868198.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44001..44219
                     /locus_tag="KB969_000179"
     CDS             44001..44219
                     /locus_tag="KB969_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBB6868199.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44355..44894
                     /locus_tag="KB969_000180"
     CDS             44355..44894
                     /locus_tag="KB969_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBB6868200.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44887..47160
                     /locus_tag="KB969_000181"
     CDS             44887..47160
                     /locus_tag="KB969_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBB6868201.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47198..48244
                     /gene="holA"
                     /locus_tag="KB969_000182"
     CDS             47198..48244
                     /gene="holA"
                     /locus_tag="KB969_000182"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBB6868202.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48333..48587)
                     /locus_tag="KB969_000183"
     CDS             complement(48333..48587)
                     /locus_tag="KB969_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBB6868203.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48987..49256)
                     /locus_tag="KB969_000184"
     CDS             complement(48987..49256)
                     /locus_tag="KB969_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868204.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49726..50181)
                     /locus_tag="KB969_000185"
     CDS             complement(49726..50181)
                     /locus_tag="KB969_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBB6868205.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50319..52247)
                     /locus_tag="KB969_000186"
     CDS             complement(50319..52247)
                     /locus_tag="KB969_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6868206.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52444..53277)
                     /locus_tag="KB969_000187"
     CDS             complement(52444..53277)
                     /locus_tag="KB969_000187"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBB6868207.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53469..54173)
                     /locus_tag="KB969_000188"
     CDS             complement(53469..54173)
                     /locus_tag="KB969_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6868208.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54196..54822)
                     /locus_tag="KB969_000189"
     CDS             complement(54196..54822)
                     /locus_tag="KB969_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6868209.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55148..57523
                     /locus_tag="KB969_000190"
     CDS             55148..57523
                     /locus_tag="KB969_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBB6868210.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57547..58038)
                     /locus_tag="KB969_000191"
     CDS             complement(57547..58038)
                     /locus_tag="KB969_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBB6868211.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58225..59145
                     /locus_tag="KB969_000192"
     CDS             58225..59145
                     /locus_tag="KB969_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6868212.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59299..59643
                     /locus_tag="KB969_000193"
     CDS             59299..59643
                     /locus_tag="KB969_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBB6868213.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59833..60333)
                     /locus_tag="KB969_000194"
     CDS             complement(59833..60333)
                     /locus_tag="KB969_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868214.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60861..60944
                     /locus_tag="KB969_000195"
     tRNA            60861..60944
                     /locus_tag="KB969_000195"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60895..60897,aa:Leu,seq:cag)
     gene            complement(61268..61906)
                     /locus_tag="KB969_000196"
     CDS             complement(61268..61906)
                     /locus_tag="KB969_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6868215.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            62241..62675
                     /locus_tag="KB969_000197"
     CDS             62241..62675
                     /locus_tag="KB969_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6868216.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            62698..63018
                     /locus_tag="KB969_000198"
     CDS             62698..63018
                     /locus_tag="KB969_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868217.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            63159..63350
                     /locus_tag="KB969_000199"
     CDS             63159..63350
                     /locus_tag="KB969_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868218.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(63421..63678)
                     /locus_tag="KB969_000200"
     CDS             complement(63421..63678)
                     /locus_tag="KB969_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBB6868219.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            63836..64099
                     /locus_tag="KB969_000201"
     CDS             63836..64099
                     /locus_tag="KB969_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868220.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            64123..64311
                     /locus_tag="KB969_000202"
     CDS             64123..64311
                     /locus_tag="KB969_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868221.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(64394..64579)
                     /locus_tag="KB969_000203"
     CDS             complement(64394..64579)
                     /locus_tag="KB969_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868222.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            64794..65165
                     /locus_tag="KB969_000204"
     CDS             64794..65165
                     /locus_tag="KB969_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6868223.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(65315..65387)
                     /locus_tag="KB969_000205"
     tRNA            complement(65315..65387)
                     /locus_tag="KB969_000205"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(65352..65354),aa:Gln,seq:ctg)
     gene            complement(65433..65861)
                     /locus_tag="KB969_000206"
     CDS             complement(65433..65861)
                     /locus_tag="KB969_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868224.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(65921..66679)
                     /locus_tag="KB969_000207"
     CDS             complement(65921..66679)
                     /locus_tag="KB969_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBB6868225.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            66974..67171
                     /locus_tag="KB969_000208"
     CDS             66974..67171
                     /locus_tag="KB969_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868226.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            67277..67759
                     /locus_tag="KB969_000209"
     CDS             67277..67759
                     /locus_tag="KB969_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868227.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(67817..68413)
                     /locus_tag="KB969_000210"
     CDS             complement(67817..68413)
                     /locus_tag="KB969_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6868228.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
BASE COUNT        22574 a        11723 c        14575 g        19747 t
ORIGIN      
        1 gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc aataatagga
       61 acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa aaatagagga
      121 attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga tgttgcagca
      181 agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg atacgataat
      241 gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct ttgtgttctg
      301 tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct cggcggattt
      361 ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg atcgacagca
      421 aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa agctgacctt
      481 gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa atttttagtt
      541 aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta taagattttc
      601 gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca tatttttgtt
      661 gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa aacgatgtat
      721 ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac ttttgtatga
      781 aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga tagaatattt
      841 agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa aaggagaatt
      901 gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa taaaaaatca
      961 ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa ttatccctct
     1021 ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag gtgttcccga
     1081 aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc agttggatga
     1141 tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg aagaaatcag
     1201 tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat ttgctaaggt
     1261 cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac aaattttgct
     1321 tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga atgaacatat
     1381 ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc aagaagtata
     1441 taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt cgtaaaagta
     1501 tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa aaaagcagtc
     1561 catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt tgagatacaa
     1621 cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga caagctgctt
     1681 gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga agtataacat
     1741 gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt tatgggcagt
     1801 tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct ctttagaagg
     1861 atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga gatgcggtgc
     1921 gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag aagggaaacc
     1981 agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt tgccaggtgt
     2041 actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga aagtcaaccc
     2101 caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc cagttgctca
     2161 tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa aaaataatca
     2221 gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg cagggattac
     2281 gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag tagaagactt
     2341 gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact tcggaaaggt
     2401 gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga aaaaaagaat
     2461 ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag atatcttagg
     2521 aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg aacattgttc
     2581 ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc atgtgttgca
     2641 aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag ttgtcttcaa
     2701 agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg cgacaggagt
     2761 tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt tgctagattc
     2821 attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag aagtagttgc
     2881 aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg aaattgcatt
     2941 tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt tgattgaaca
     3001 caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt atgtaggtgc
     3061 aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat ttaatcaaga
     3121 agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa agctgctgct
     3181 tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta tacaggatat
     3241 gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg gctcaggact
     3301 tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt atgaaatgat
     3361 gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg aagaaaaaat
     3421 ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag taacagacga
     3481 cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag tcgatgcatt
     3541 agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa tcgtagaatt
     3601 tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat tgcttgatct
     3661 gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg attcacaagt
     3721 acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg ttagagggac
     3781 gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt tggatccaaa
     3841 aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta gcggtggtaa
     3901 gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag aagttttttg
     3961 ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag gaactcctgt
     4021 tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct atccaacacc
     4081 aatgattggt atggtcggat tgattgagga tcataaacat atcactactc aggaattcaa
     4141 aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg atggcagtga
     4201 attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg atctatccat
     4261 tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga ttgaaagtgc
     4321 tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt tcaaacatca
     4381 gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag aaactcaatc
     4441 aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa tgatgggaga
     4501 tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt cagcaactga
     4561 cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg caatcgtatg
     4621 tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg gggtcatcca
     4681 gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg acaagaaggt
     4741 gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt ggggctgctt
     4801 tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc tgcaatcgga
     4861 catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc ttttctattc
     4921 aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa tgctcgttcc
     4981 cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga tacggagata
     5041 ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt aaaaagtgct
     5101 ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc aatgattgcc
     5161 gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa cggagcatac
     5221 gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat aagagatgtc
     5281 cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg ctttacgaag
     5341 gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc agattcaaac
     5401 atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt agcgaaagaa
     5461 tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc agccgcaagc
     5521 ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa tcaatacatt
     5581 gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg aatgaaatta
     5641 tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga ttcaattgtt
     5701 cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc aaaagaagtc
     5761 catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat tgatattcaa
     5821 acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga atgtatcggt
     5881 gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg tctggaaaaa
     5941 gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc gacgccgtta
     6001 tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt cttttaaaag
     6061 cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag ctggcgtaga
     6121 tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa aaacggaacg
     6181 tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat cggtctttca
     6241 attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat tagcagtggc
     6301 aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt gtgtcaatga
     6361 tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa cggggaaaaa
     6421 tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg ttcaaggaaa
     6481 tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag gtaatgatta
     6541 tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga caggagaaac
     6601 gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt caaatgggta
     6661 ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat caaaactgcc
     6721 agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct atgtttcttc
     6781 cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca ctggtggagg
     6841 gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa tcaaacttgg
     6901 ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa ttcctgagat
     6961 ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc aagaatcgaa
     7021 agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg aaatcgggaa
     7081 agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat gagaatcgct
     7141 gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct atcgaaaaaa
     7201 ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata tgttttgaaa
     7261 cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt tgattcaaaa
     7321 aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga tttgatcgta
     7381 ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga taaaagaatc
     7441 atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat acgtgatgcc
     7501 tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca aggtgtagat
     7561 actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac gttcgattct
     7621 ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat tagtgaaatt
     7681 attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca gataaaactg
     7741 ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt tcaacaggag
     7801 gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa gaagtgacag
     7861 ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc catggtggtc
     7921 ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa aatatccaac
     7981 caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg aaaccagatg
     8041 tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg ctccgtagtg
     8101 cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat gaagaagtac
     8161 tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa ctagcggcaa
     8221 aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta acggattggg
     8281 tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa acgcttcgtt
     8341 acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg gaaaaatatt
     8401 cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat atccgagatg
     8461 cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc gccttgaaac
     8521 acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg gaagcagcgt
     8581 atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga gaagtagatc
     8641 tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc ccttcttata
     8701 cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg acagtagact
     8761 ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt ggacttcttg
     8821 tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg acaaaacgta
     8881 agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc aaacatgtga
     8941 aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga gccgggcaga
     9001 tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa atggaaggtg
     9061 cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat gcagccaaac
     9121 atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat tctattgata
     9181 tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt agacattaga
     9241 gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa catgcaataa
     9301 gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca ggaaatccgg
     9361 ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat tcagcgttaa
     9421 tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa gttcctttgt
     9481 taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt ccgacaaaag
     9541 cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat acttatcaaa
     9601 tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg tatatcaaag
     9661 aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa ggtgtagtcg
     9721 tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac cagcatcgat
     9781 ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa gaattctccc
     9841 ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa gatcataagc
     9901 gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat tcaccagtac
     9961 cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa ccagcggctt
    10021 tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt ttgattgcta
    10081 cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct gaaacgcaag
    10141 tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta ttagagaatc
    10201 gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg gttgcagctg
    10261 ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg gaagaagagc
    10321 tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga gcaggaggac
    10381 gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa aaaatttaca
    10441 ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt ggagaaaaag
    10501 ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa aaaatacaac
    10561 aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt ggtacacttt
    10621 tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg tacttctgat
    10681 cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga agatccagta
    10741 aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc agatatttat
    10801 ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc aatcaaacga
    10861 gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt tgatttttct
    10921 aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat ggattatgtg
    10981 gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt agctgaagcg
    11041 tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa tcaaaaacca
    11101 atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa tcagctgcaa
    11161 tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat gacagatgaa
    11221 gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga tatgacgatc
    11281 caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg gaacgaaaaa
    11341 ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac gacaccaact
    11401 ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat cgccggtacg
    11461 atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat gtctcgggaa
    11521 gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt gtcataagca
    11581 ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt cagcttcgag
    11641 atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt tcgtttatta
    11701 gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa tcccttgttt
    11761 tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa aagcaatatc
    11821 tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc tttgttctgt
    11881 cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga aatgagaggg
    11941 acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg taaaattttc
    12001 tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg aaggctgtga
    12061 gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa gcgagtcgtc
    12121 ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt gcgggatttt
    12181 cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac gatataatcg
    12241 tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag atacttcgtt
    12301 tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat caactggaag
    12361 tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg aactggcggt
    12421 ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc tttctgcgac
    12481 aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat ggaccaacgt
    12541 ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa ctattaaaaa
    12601 tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc taaataaaaa
    12661 cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt ggtttgctgc
    12721 taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag caagtttcaa
    12781 tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat tttttttcaa
    12841 ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta aagcagttac
    12901 tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca gataatcatc
    12961 tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac taataaatat
    13021 gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc cgtccatgaa
    13081 aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg aagacagtgc
    13141 catctcacca tctccagctt cgccgacata agtgattgga taataagaac caaggacagt
    13201 tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa aaactttata
    13261 catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg acagttgttc
    13321 cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa taaagaagga
    13381 gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg atccctttgg
    13441 ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg ttgtctataa
    13501 ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat cctttgtgac
    13561 ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag atcattttta
    13621 aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc atatggccgt
    13681 atcttatttt taagatgact agataatcat tgatatggct aatttctttt tcaagaggaa
    13741 tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca tgggtcatag
    13801 tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc aaactgttat
    13861 aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt gctaaatggt
    13921 attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt ttattcatgc
    13981 tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag ccaaggttcc
    14041 ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg acctttctct
    14101 ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact ccaagttcca
    14161 ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt gctaagtcga
    14221 tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca gaatctacct
    14281 gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta ttgatcagct
    14341 cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac gtactaattt
    14401 ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt tcttctagga
    14461 tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc cacatacttt
    14521 ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata tttgcgatcg
    14581 tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc aaagggataa
    14641 cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg cttaaatttt
    14701 ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat attctgctgg
    14761 gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt ttgaatattt
    14821 ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt acactcgact
    14881 acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc atcaatagtt
    14941 acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc taaagcaccg
    15001 tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc atttgtttct
    15061 aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac aattcggtga
    15121 acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt tggtttacga
    15181 ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt ctctgaacca
    15241 gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt gctgacaaat
    15301 aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac gaaaagctcg
    15361 ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc tcgctttgct
    15421 tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat catatccact
    15481 ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat gtagccattt
    15541 cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc agtatgcttt
    15601 ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg gtcaggtgct
    15661 tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag ggctaaaaaa
    15721 aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta tcttatcaga
    15781 taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa acttaaaaaa
    15841 atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa aaaatcaatg
    15901 ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga taaaaaatga
    15961 aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc attctattaa
    16021 gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga atcgctatgc
    16081 cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg gaattagaaa
    16141 aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat caagtagcac
    16201 aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct atcgatggtt
    16261 cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg atcgcctatg
    16321 atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat aattttggag
    16381 taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa ggaaaaggac
    16441 cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta atcaattaca
    16501 acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc gtgccatctg
    16561 gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg gcgcaagcaa
    16621 ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct gttttgtcgc
    16681 catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg tatgggagtg
    16741 aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc gttaaatcga
    16801 tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta gcaaaaaata
    16861 cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat gatactgaaa
    16921 cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta tctgtcgata
    16981 aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc gatctgaaaa
    17041 attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga taagaattat
    17101 ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa tccgagcgtt
    17161 agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg gagaaaacgg
    17221 agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg gctcctatga
    17281 cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag atagtgaaga
    17341 aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt caataaaaga
    17401 gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg aactgacaga
    17461 aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga atcttctagt
    17521 atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat tatcaaaatc
    17581 cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag aaagcgcgaa
    17641 tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca ttatttcaca
    17701 taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg atggacagac
    17761 gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg gaatggtggg
    17821 cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag tttattttaa
    17881 agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa acgaccacat
    17941 caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg gagcgggcag
    18001 aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat ccggacgtat
    18061 attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg caaacggact
    18121 cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg atattcggga
    18181 aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag ataaagaaaa
    18241 agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa actccatcca
    18301 tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat ccaagtggct
    18361 gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag atgttggggc
    18421 aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag ctgtctgtct
    18481 tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata cgatgaacga
    18541 aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct tgatgaaatt
    18601 aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg gataaaaaag
    18661 agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac agcatggtga
    18721 tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt ttctggcgtc
    18781 cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta gctgcaggga
    18841 tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg atggcgtttg
    18901 ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg atgacagtta
    18961 tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg gtagcttatg
    19021 cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt ggactgacac
    19081 aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa aaaatgtcta
    19141 cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca ttgattttag
    19201 gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat cgtcggaaaa
    19261 atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta tttacagcag
    19321 tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg attattttga
    19381 tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca gtagcaggtc
    19441 gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg atcaaaacaa
    19501 agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta gctggattag
    19561 ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg gaactggatg
    19621 caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga acaatcatgg
    19681 gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg attttaggcg
    19741 tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc gttgtgctag
    19801 acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca gaaaaaagac
    19861 tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca ttgtttcgtt
    19921 tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc tttttgctct
    19981 tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc ttgattaaat
    20041 taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat gaaagtattt
    20101 gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg ttctgaatgt
    20161 gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc tgccaacatg
    20221 cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta tttctatatc
    20281 atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa aaagcgtgga
    20341 ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat agagaagttg
    20401 gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg acatgctaac
    20461 tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt tgtgattgcc
    20521 ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc agatgcaaca
    20581 aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg ctttgggact
    20641 ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa gccgatcatc
    20701 gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt tggtgcgaca
    20761 atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga aacaaaagtc
    20821 gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca aaaaggcgaa
    20881 aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt gaaagataca
    20941 ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg aagagatctg
    21001 gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa tggagacaca
    21061 atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca ttaagtaata
    21121 agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt attatcgcag
    21181 atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt tttgtcacag
    21241 tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta aaatcaaaag
    21301 aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa aaacaaggac
    21361 cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga aggatcaatc
    21421 ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg aatcgttcca
    21481 ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc aaacgtggca
    21541 gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga atcgattggc
    21601 ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa ataagagaag
    21661 caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg ccagatgagc
    21721 ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg gaagaaaaag
    21781 aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat ttggaaagta
    21841 aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt cagcaagcaa
    21901 tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta gagtcacctt
    21961 ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt gggataccga
    22021 tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa aataaattga
    22081 aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg agtcaaaaac
    22141 gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt gaagacgatg
    22201 tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga acgattgatc
    22261 cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca acgaaaatcg
    22321 gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa gaaatgatgg
    22381 agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat gaagcaattg
    22441 atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg ataagcgctt
    22501 ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac tatgcctgga
    22561 ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta gatatgggtc
    22621 ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga atcaattaca
    22681 gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt ctagaaaagt
    22741 ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct tggatttaaa
    22801 tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact aagaaaaaac
    22861 cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa caaaactgta
    22921 taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa aatagaaaaa
    22981 atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat gctgttaata
    23041 tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt gtatttctca
    23101 taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt tattcactgt
    23161 ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg acaaatggca
    23221 aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc agatttccca
    23281 gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt acctgattta
    23341 tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt attagaccaa
    23401 cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac tgctggacaa
    23461 gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct tcttccaggt
    23521 tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc ttttttatgg
    23581 tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct accaccacaa
    23641 attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt gaagaaacga
    23701 aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca aggtgatttt
    23761 tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta tatccaaaac
    23821 aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac acttgcacaa
    23881 aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc gcttgcagta
    23941 tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc agtcctaatc
    24001 gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc aacccgctac
    24061 cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg cttccgtaaa
    24121 tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat cgaagcaact
    24181 aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca aaaggtttca
    24241 gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca aattgcaatt
    24301 tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa gcaatcacag
    24361 atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt gaagatgttg
    24421 ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc ggagaagacc
    24481 gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc ggtcttgcgt
    24541 tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc gaagcaatgg
    24601 acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact agaaatctac
    24661 ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg cattcggata
    24721 atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct tccaaccctt
    24781 atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt gttttcctag
    24841 aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct tacgaagttc
    24901 ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc acatacggag
    24961 caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat atatctgttg
    25021 aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt caatccgtgg
    25081 aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc gttgccgcgc
    25141 aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca atcggacgag
    25201 tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg ttgccaaatg
    25261 caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag aagggacgaa
    25321 acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc gcagaaggtg
    25381 aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat acattactag
    25441 aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga acggttaaaa
    25501 atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta gaaatcgatg
    25561 caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc caaactccag
    25621 ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca agcgaaggag
    25681 tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa atcgtcaaat
    25741 ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa gttcaaaatg
    25801 acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac gtgattgttc
    25861 cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct cctggacaca
    25921 atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat
    25981 caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg gctatgccat
    26041 ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact gcaactggaa
    26101 aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg
    26161 caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct cctgcagcag
    26221 aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac ttggaagaac
    26281 gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac agtaagcata
    26341 cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg gataatcgga
    26401 aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg ccatatgtcg
    26461 tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct atcgacgatg
    26521 caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact gatacggatc
    26581 acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt gctattgcag
    26641 acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca gaagatatgc
    26701 gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg tttacaccag
    26761 tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa caaccaatcg
    26821 taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc
    26881 accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa cgtcttttag
    26941 ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg agattttgct
    27001 gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc tgccatccgc
    27061 gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg cggtgtttgt
    27121 ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca ttatcaagag
    27181 tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa
    27241 acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt tggtttccta
    27301 ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca
    27361 ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc aatcatcgca
    27421 acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt gttagattct
    27481 actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg tggcggtgtg
    27541 attggtgccg aattgggcgg agcgtacgca aacttaggag cagaagtaac gattcttgaa
    27601 ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt agaagatgat
    27661 ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac
    27721 ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt tactgctgat
    27781 tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt agaacaagcg
    27841 ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg tacgaacgta
    27901 cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca caaagccagt
    27961 tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt agattataaa
    28021 gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat gacgatcaaa
    28081 gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc agggaacggt
    28141 cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac gatcgaagat
    28201 aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta
    28261 gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat tcatcctcat
    28321 ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt accaatccat
    28381 atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta
    28441 gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg gtttattacc
    28501 acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg caagaatatc
    28561 agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg aagatgtggg
    28621 aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg aagacttatc
    28681 agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga cgggaatttg
    28741 aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca
    28801 aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata tcaagtcctg
    28861 gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa
    28921 atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt ttctaatcga
    28981 aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag ggtgtaatca
    29041 attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca ccttgaattt
    29101 tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg gcgttggaaa
    29161 gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa aaggaatagg
    29221 cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat cggaaggctt
    29281 acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag aaattgcgga
    29341 aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg caatcttgaa
    29401 aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag cgggaaatgt
    29461 cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt tgacatttga
    29521 aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg cagacctttt
    29581 gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa
    29641 agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa aagtctgcta
    29701 taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa ggagttagtt
    29761 acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga
    29821 aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc acatacgcaa
    29881 ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta
    29941 gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga tactccagga
    30001 cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg
    30061 gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa aaaagcactg
    30121 gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc tgctcgtcct
    30181 gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga tgatgatcag
    30241 ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt gtcagatgat
    30301 ccagcagatc aagaaccaac catggcacct atttttgata caattattga aaaaatccct
    30361 gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact tgactacaac
    30421 gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa agtaggagac
    30481 caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac gaaattattt
    30541 ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga cttgattgct
    30601 gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat
    30661 gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt agttaataat
    30721 tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga agaacgtttg
    30781 atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc tccagatgca
    30841 tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa catgcgccgt
    30901 gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat cgacggtgta
    30961 aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat gggtagtgtt
    31021 atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac aggaaacgga
    31081 caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc aactgaattc
    31141 ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata tctgccaatg
    31201 cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa
    31261 gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt
    31321 acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga tttgactgtc
    31381 aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga ccaaacatct
    31441 gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt gaatgatgat
    31501 gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt agagaaaaat
    31561 gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag agagaaacca
    31621 gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt ggagaagtca
    31681 tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa
    31741 aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga aaggagatca
    31801 acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg
    31861 acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa gaaattatcc
    31921 agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt gggaaatcaa
    31981 tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg tcccctttaa
    32041 tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc gccactttta
    32101 tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc gatagacagc
    32161 agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt atccaagcaa
    32221 tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc tctcagtggg
    32281 ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa ctgccaaatc
    32341 gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct gacataaaaa
    32401 gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga gaaaatctac
    32461 gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat ttaaagatca
    32521 acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac cgtctctatc
    32581 atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta aatgagaatg
    32641 agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt gtagcgacaa
    32701 atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat tatcaaattc
    32761 ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat ggtctttcca
    32821 gtgaagccat cctgcttttc tctcctcaag atatccaagt ccaaaagttt tttatccagc
    32881 agtcccaaag agaagaaggg caaaagcaaa aagaatatga aaaattaaaa gcgatgacag
    32941 aatacgtgta tattgagtcc tgtcttcagc aatacatcct aaactatttt ggcgagacaa
    33001 gcagtccgtg caaccgttgt ggtaactgtt tagatgacag agaaatagta gaagtaacga
    33061 cagaagcaca gatggttctt tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa
    33121 tgctgatgaa agtcttagca ggatcgaaag aacaaaagct gcaagcttta ggttttggac
    33181 atttatctac ctatggactg atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg
    33241 aatatttgat atcgaatggc tatcttctga ccatcaatgg tgagtatcct gttttgaaag
    33301 taacagaaag agggatacaa gtattgaaag gacaagaatc tgtttatcga aaggaaccca
    33361 agaaagtcca gcagctatcg gatgaagaaa ccgatacact atttgaagtg ctgcgggaac
    33421 tgcgaacgga tctagcatca gaagcaggcg ttcccccgta tgtcgtattt tcagattcca
    33481 cattgaaaga aatgagccga atacgtccat caagcagatt ggagatgctt cagataaaag
    33541 gagttggcca aagcaagctt gataaatatg gcgaagcctt tttatctcgg ataaaaaatg
    33601 cggactctaa cgttctggat aagtagaaag aacgaatacg taaaaatgaa taaaaacaac
    33661 tggttaaatc tgtttttttt gctccttatg aaaatcaaat atgttataat taaggaatta
    33721 gaatgggagg taagcacaga tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa
    33781 tgatgaagca gaacggatca aacgattaat ccgaaatcaa aacaacagtc tctgtatctc
    33841 acaatgcaaa gccttcgaag aagtggtaga tacacagatg tacggctttt cccggcaagt
    33901 cggttttgct gtccgtatag gagtaatcgg aaagaacgag ggccagctga tgttaagtga
    33961 gctagaacga gaattgaatc agttatatag tgaggtttac caagaaattt atgataaaaa
    34021 agaagttggc aaggaggaat agacttgcct aagaaagtga aaaaaaggca tctattagac
    34081 tatagcatct tgattcccta tttaatttta tgtgtattgg gattgatcat ggtatatagt
    34141 tctacgtcgt atctattatt agaaaacgga caaaatccgt ccgcatcagt cattaaccag
    34201 agtatttttt gggtgcttag cttgattgct atcgcactac tttataaaat gaaaacagat
    34261 gttttgaaaa accagcgttt gatcatggca gccatcgcag ttttgacgat tttgctgctg
    34321 attgttgtgt tttttggtaa ggagatcaat ggggcgaaag gttggctgca aattgcagga
    34381 ttctcgatcc aacctgccga atacctaaaa atcatttcta tctggtacct gtctctgact
    34441 ttatctaaaa gacaaaacag tgtacaaaaa gattttcttg ggactgtgaa acgtccactt
    34501 gcaatggtta tcggacttac tgcattagtc gctattcttc ccgattttgg taatgcggca
    34561 gttatctttt tgattatttt ggttctgctt ttagccagcg gagtcaatta tgtgtatact
    34621 ttgattgtag gagtaggagg cttttgtcta agtactttta cgatctggct gatcaatatc
    34681 acaaacggaa agatcttacc cggacgttta cagtatatct ataatcgatt tgctatttac
    34741 caaaatcctt tctcagacga attaaataaa gggcatcaac tagtcaacgg ctactatgcc
    34801 atgttcaacg gaggactatt tggcagggga ttaggtaaca gtatccagaa aaaaggattt
    34861 ttacaagaag cacaaaccga ttttatttat gcaatcgtag tggaagaact gggagtgatt
    34921 atggggattt tgatattagc gttgctattc tttatgattg tgcgcattgt ccttgtaggt
    34981 atccgttcaa aagatccgtt caattcgctt ttgtgcattg ggatcggcgc aatgtttttg
    35041 atccaagtat ttgtcaatct tggaggaatt actggcgtta ttcctttgac agggatcacg
    35101 ttcccatttt taagtcaagg aggctccagt ttgctgatgc tttcgatttg tgtcggcttt
    35161 gtcctcaaca tcagtgcgga tgaaaaacgc aagagcttag gtttataata aaaaaagatg
    35221 taggagtggt tcgatgaaaa aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt
    35281 atttcgtgct tgtacagaat taggaattaa aactgttgga atctatgcag aagaagatga
    35341 atattccgta caccgtttca aagcggatga agcatattta gtaggacaag gaaaaaaacc
    35401 gattgatgcg tatctagata ttgaagggat catttctatc gcgaaagaat gcggagctga
    35461 cgctattcat ccgggttacg gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga
    35521 agaagaaggc atcatttttg ttggacccaa actgcatcat ttagatattt ttggagataa
    35581 aatcaaagca aaagctgcag ctatcgaagc ggggattgct tcgattccag gcacagatgg
    35641 accaatcgct tctatagacg atgccttgga gtttgcgaaa caatacggtt atccgattat
    35701 gatcaaggca gctctaggcg gcggcggacg cggcatgcgt gtagctcacg atgaaaagag
    35761 tgcaagagag ggctacgaac gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga
    35821 agtgtatgtt gaaaaataca tcgctaatcc taagcatatc gaagtacaga ttctcgggga
    35881 tacgcatgga aacgtcatcc atctttttga aagagattgt tctgttcagc gccgtcacca
    35941 aaaagtagta gaagtagcgc cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg
    36001 ccaggcagct gtccaattga tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt
    36061 tcttgttgaa ggagatgatt tttactttat cgaagtcaac cctcgcgtcc aagtggaaca
    36121 tacgatcaca gaaatgatta cagatattga tatcgtaaca acgcaactgt tgattgctca
    36181 aggtttggat ctgcataaag aaatcggatt gcctcagcaa gaaggaatta aattaaatgg
    36241 ttcagccatt caatgccgaa tcactacaga agacccgttg aataactttt taccagacac
    36301 agggaaaatc gatacgtatc gttcacctgg tggttttggc gtacgtctgg atgtcggaaa
    36361 tgcttacgcg ggctatgtag tgacaccgta ttttgattca ttgctagtaa aagtatgtac
    36421 gcatggtgct acctttgaaa cagccattca gaaaatggaa cgttgcttga aagaatttag
    36481 aatccgtgga gtgaaaacaa acattccatt tatgctcaat gtcatcacac atcctgaatt
    36541 ccaatcagga aatgcaaaaa caaccttcat tgatagtaca gcaacattat ttgaatttcc
    36601 tcgactacga gaccgcggaa acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg
    36661 ttttccaggt atcgaaagtg gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga
    36721 tctaatcaca agaactgatt acgtaacggc taagaatgta ttagatgcga agggtgccga
    36781 tgctttggtc gaatggatca aaggacagga aaatttgttg ttgacggata cgacatttag
    36841 agacgcccat caaagtctgc tagcaactcg tgttcggaca aaggatttca agcagattgc
    36901 acgtttgact ggagaaggtc ttcctgaact cttttcaagt gagatgtggg ggggagcaac
    36961 atttgatgtg gcttaccgct ttttgaatga agatccttgg caacggttga gaaaaattcg
    37021 ttctttaatg cctaatacgt tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta
    37081 ttctaattat cctgacaatg tattggtgga atttgtcaaa gaagcagcag cgcaaggaat
    37141 cgatgtattt cgaatctttg atagtttgaa ctggactcca caaatggaaa aaagtatcca
    37201 agctgtacgg gatactggta aaatcgcaga ggcagctatt tgctatactg gcgatatcaa
    37261 cgatccaagt cgggcaaaat acaatgttca gtattataaa gacatggcaa aggaactaga
    37321 acaactgggt gcgcatatca ttgcaatcaa agatatggct gggctgctta aaccgcaggc
    37381 agcttatcgt ttgattagtg aattgaaaga aacgacagat ctgccaatcc atctgcatac
    37441 tcatgatacc agcgggaatg gaatcatcac ttattctgct gcttcaaaag caggagtaga
    37501 catcgttgac gtggcaatga gtgcaatgag tgggaatact agtcagccta gcatgagcag
    37561 cttgtattat gcactggtca atggtccacg gctgccagaa atcacgattg aaaatgcaca
    37621 gaaattaaac cattattggg aagatgtgcg catgtattac aaaccgtttg aaaacggctt
    37681 gaatgctcct gaaacagaag tatatatgca tgaaatgcca ggaggacagt attcgaatct
    37741 acagcaacag gcaaaagctg tcggattagg tcatcgctgg gatgaaatca aacaaatgta
    37801 tcatactgtc aacttgatgt ttggcgatat cgttaaagta actccatcat ctaaagtagt
    37861 tggagatatg gcactattta tggtccaaaa tgatcttaca gaagaagata tttatgaaaa
    37921 aggcgaaaca ctaagtttcc ctgaatctgt tgtgactttc ttccaaggag aactagggca
    37981 acccgttggc ggatttccta aaaaattgca aaagattatt cttaaaggca gacctgcatt
    38041 gaatgaacgt ccaggtcttt tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt
    38101 ggcagaaaaa attggctatg aaccaaaaca agacgaagta ttaagctatt tgatgtatcc
    38161 gcaagtcttt ttggactatc aaaaagcata taatcaattt ggcgatgtta cattactgga
    38221 cacaccaaca tttttccaag gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg
    38281 cggaaaaacg cttatcattc gtttagatga aatcggagaa cccgatatcg aagggaatcg
    38341 cgtactgttc ttcaatttga atggacaaag acgtgaaatc actatcaaag ataattcgat
    38401 catcagtacg gtccaaaccc gattgaaagc tgaaccgaca aaccgagaac aaattggagc
    38461 aacgatgtct ggttctgttt tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg
    38521 tgatacgttg atgattactg aagcgatgaa aatggaaacg gccatcgaag cacgttttga
    38581 cggagaagtc gcacatgtat atgtgtcttc aggagacact atttcgtctg gtgacctttt
    38641 gattgaagtg actgagaaat aataagcgaa aggtggggaa acatgaaaag actgggtttg
    38701 ttttggctga ttctgctatt agttattgtg gcattctaca tggaaccagt cttgtttccg
    38761 ccaaaacttg aagtgaagga aaactctgat caacaaatat caaaccaaat gacaacgtgg
    38821 aaataccagg agcttaaagc aactggtttt tctacttata tcggaaaacc gatcgatcag
    38881 ctggaaaagg attttggcca agcctatgat cgattaacta gcggatttgg ttttgaaaca
    38941 agatattatg aaaataaagc tagtcatctc acatttgaag cgaacatcca agacagcaga
    39001 gtcacaactg ttaaagtact gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg
    39061 atgacgatgc aagatcttac gaaaatcact actatctata ctaatttcac ttttgagtac
    39121 catgatacag aagttggaat cgaactaatg gaagaggata tgaattatcg tccgctaatt
    39181 gcttttgata acgacacttt tgctatttta ttttttgatc aaacaacaaa cggcctattt
    39241 tcagttgtgt atttagataa agatagtctt ttgaaactat tgccatatca agtgtttggt
    39301 gaaggccttc cacattatca agcagataaa tcggctgatt gggaatcaat caatcgcgtt
    39361 aaagaacgaa aaagtacgac tttattaaat atgcttagaa gagaagacga acttcccata
    39421 tacaatcaaa cacttgcctt tcaaaaccac agtcagctgc tactacatga ttttttgaca
    39481 aggcctgagg aaatattgtc agaggaacgt atggctgatt ggcaaaaatc gctaggcagt
    39541 gctcaaacga cagtgaaatt ctcactgacg aatgatgaat tggagaagtt aatcagtaaa
    39601 caaaaattag aaaatactag tgggctattt attcatccgg cgattgacgc tactttttcg
    39661 tttttatatt ggtacagcga tccttacaac catgaccgtt tcatggaccc gggaacggat
    39721 tctgtaggca ttgctttttc taaagaaaat atgttagtct tattgcaaga agaaaacgga
    39781 gaaagtagtg atagcagtga tcgttaacga agagctgttt caactggagg atcaatgcct
    39841 ccaagtcgct gaaatgataa aaaagagtaa aacgatggct tcttatcttg aacataaaca
    39901 gtcaatggaa gaatctgcaa aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga
    39961 agcatttgaa aatgtagcgg catatggtga gtatgcacct gattatcgtg aaaaaaaacg
    40021 agctgttcga aaagcaaaaa gacagcttga tatggatgag catgttgcag ctttccgata
    40081 tagtgaaaca cagctgcaaa gtctgttgga tcaaattgtc caagtacttg ccgaagaagt
    40141 ttctaatgaa atcaaagtag atgcaggtag cccgtttttt gaaacgaaaa aacactttgg
    40201 atgcggaggt aattgtcatg caattagaca atagtgaatt tgaaataaca aaacgacgcg
    40261 ggctgatcgt atgggtctac agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt
    40321 tgcattatgt ctcaagaaga atgaaatatg tcgtgcttta cttaaatgaa gagacattgg
    40381 aagaaacaga agaacgaatc cgtaaattac attttgttcg aaacgtagaa cgttcttacc
    40441 gaccggatat cgaaatgaat tttgccgaaa aaataggaaa caaaacagta ttaaaagacg
    40501 aaggtttcga aattgaagag ctaaatacag aaatccgatt agctgaacat ctttaaaaat
    40561 ctcttatgag cagtttttaa ataaaaaata acttggataa cgatcgattt ttgatcattg
    40621 tccaagtatt tttttggtat actagtacca gtaccatttc taaggagtga gtagatgcgg
    40681 ataatatcag gaaattatgg cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga
    40741 ccaactacag ataaagtaaa agaatccata ttcaatatga ttggaccata ttttgatgga
    40801 gagacagtat tggatctgtt tgcaggaagc ggtggtttag ctatcgaagc agtatctaga
    40861 ggctgcagtc atgcggtatg cgtagacaaa aattaccaag cgctaaaaat catcaaagaa
    40921 aacatcgaaa ttacgaaaga accagagaaa tttaccacaa taaaacttga tgcggacaaa
    40981 gcaatcgaac ggctagcagc ggagaaacaa caattcgact acttgtttct tgatccgcca
    41041 tatgcaaaac aaaaaataat cgatcaaatc cataaaatgg aagaactggg acttttttct
    41101 aaaaccgcag ttatcgtatg cgaaacggat aaaacagtcg aattgccaga aactgtggct
    41161 ggattccatc aaataagaaa acagatttat ggcataacgg ccgtaactat ctatagaaaa
    41221 gagggaaatc aatgaaacgt gcattattcc caggaagttt tgatcctttt acaaaaggtc
    41281 acttagatac ggtggaacgt gcggctaaat tattcgatga ggtagtaatt ggtgttttta
    41341 tcaatacttc aaagaaaagt ttgtttcccc cagaagaaag aatgacattg atcacaaaag
    41401 ctgtttctca tcttcctaat gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa
    41461 cagcaaaaga gattggtgca gatgcgttga tcagaggcat acgaagtatc aaagactttg
    41521 aatatgaacg agagattgct cagatgaatc atcatctata tgatgaattg gaaactgtct
    41581 tcttattagc aaaaccagaa tatagtcacg tgagttccag tattttaaaa gaagtactgc
    41641 actttggcgg agatgtgagc agctacttac cgccagtgat caacgaagct ttagctggaa
    41701 agcgtgaatc aaatgaaagc taaacaatgg ttgaaaacag tactgattat catatttgga
    41761 atgttgatca ttggatttgt agtagttccc ttgccgtatt atgtagaatc accgggagcc
    41821 acgatcgatc tgaaagaact aattacggtc aatgataagg aagataaagg ttctgggtct
    41881 ttctctctta cctctgttgg tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa
    41941 atgacccctt ttgaagaatt gatcagtgaa gaagaattga ctggtggggc gacaaatgaa
    42001 gaatataatc aaatgcaaca gtattatatg gattcttccc aaaatgcagc aatcgaacaa
    42061 gcgttaaaac ttgcagacaa gccttataaa atggaattca aaggcgtata tgtcatgagt
    42121 gtagagaaaa catcgaattt ctttggcaag ctttcagttg gagatacagt aacaaaagta
    42181 gacgggaaaa gctttcaaag tacagaagca tttatggatt atgtaaaaag ccaaaaagtt
    42241 ggacaaacaa tcgaaatcag ttatttgcat aatggtgaag aaaaaacagc ttctggtgat
    42301 ctgatcgagt taccaacaga taaaaaggca ggaataggta tcacgcttac tgaccatacc
    42361 gagatcgaat cagatacaga tgttcgtatt aattctggct ctatcggtgg gccatcagcg
    42421 ggattgatgt tcactttaga aatctatgaa caagtcactg gtaaaaactt gcgacatggt
    42481 aagcaaattg caggaactgg aacgatcaac agtgaaggag aagttggccg aatcggagga
    42541 atcgataaaa aagtggcaag tgcggataaa gctggcgtag agattttctt tgcaccagat
    42601 gatacgattt cagacgatgt taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa
    42661 gcaaaagctg ccgctaaaaa attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta
    42721 caagaagcgc ttgactatct agagaaaatg aaatgaaact aaataattaa agaggggttg
    42781 tgacacgagt tctgtcacaa cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa
    42841 acaaaagaaa aaattgacgt aattagatgt tgaagggacg attttgccag agctcactgt
    42901 ttcttcaatt ttaaatgaaa ggagtaatga atgattttta ctggtcattc tttgaaaaaa
    42961 gaacaatgat agaaaaaatc agcaagaaaa tactagcttc acccaaattg atcatttgga
    43021 tgtctatgat agttcttatc ttttgtatcg caagtggttt tttattatca aatttgctat
    43081 tttatagaga aacagaagag actgctgcaa aagaaatact ttcttcgttt agttccagtg
    43141 gagaagatcc atcagctgaa ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt
    43201 acaccgatat caaaggaagt gtgaaggagc ctggtatcta ttccttttct tcagaagaac
    43261 gggtctatga tgtactaaag cgtgcaggtg gattattaga agaagcggat agcgatcgaa
    43321 tcaacttttc tgcgaagata gaagatcagc aagtcctata tatccctgct gtaggtgaag
    43381 agctgccaga acatcttgat cagttggcat cctcggaagg aaaacagcct acagcagatt
    43441 ccgagcctcc caaaataaat atcaatacag ccactccatc agaacttcag cagattcctg
    43501 ggatcggatc agtcaaagcg caagaaatca ttcgatttag agaagaaaac ggatccttcc
    43561 agaaagtgga agacctgcag gagatttctg gtatcggtga aaagacagtt gaaaaactaa
    43621 aaaacttcgt tacaattaaa tagaatgatt caaaatcgac tggcacgagc aataaatgga
    43681 cgctaatgga tactaagaat aatccaattc taagagcttg gcaggacgag gaggtagtat
    43741 ttttggatag gaaatagctt gattgttcgc aaagaaacat taaaaaaacc aatgctgaat
    43801 gtctatctcc aaaataaaat atctgggatt catattatga atacggctgt cagcggcaat
    43861 aacagtcaag ctctacgaga acgctttgcc aaagatgtac ttagctatac agcagataaa
    43921 gtatttattc tcattgggac gaatgatcta gcagagcata aacaactttc taaagaaacg
    43981 taccaaaaaa tctgcagtgg atgatagttc agctgaaaaa agactatagt tctgatcatg
    44041 ctttctttat cacgccacca gcagtcgatg agacaaaaca aaaatatcgg aataacaagt
    44101 tgatcaaaga atatatctct gttctcacag aagtagcaaa acgccatgat tgtgaagtat
    44161 cgatttttat acggaatttc ttgaacaaat ggattcgaag aatttttata atgggctaat
    44221 ggatgacgga cttcatttcg gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg
    44281 ttatatttaa agaatatttt gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg
    44341 gaggaatata aaacatgtta gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag
    44401 ttactgataa gtcacataat gaacgcattc cttgggacca gtactttatg gctcaggcag
    44461 tactgttatc tttacgtagt acgtgtacac gtttagaagt aggagcgaca ctcgttcgag
    44521 aaaaaaggat cattgctggc ggctataatg gagcagtcag tggagatgtc cactgcatag
    44581 atgaagggtg ttacgtcgtg gatggacact gcttgcgaac gatccatgca gagatgaatg
    44641 cactcctaca gtgtgcaaaa cttggtatcc cgacggaagg ttcagaaatc tatgtcacac
    44701 attttccatg tttggcctgt acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt
    44761 atctccatga ctatcgaaat gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat
    44821 ctgtacacca agttgcttta gactcacagc atttttcaaa acttcaaaat gaattaacag
    44881 gaaaacatgt ctagcgtttt agaaaggcat gttcgaaatc ggttgatttt tccggcaatt
    44941 acgtcgatga ttatctgttt gttgtattac actgacaatt ggggttatcg tttgcttctt
    45001 gccggaattt ttttatggtt ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt
    45061 ttgtgtagca taacggtatc catttcttat aggctacaag agtattcatt tttagaggaa
    45121 aaaacaacat ctgcgcaaat tactgtattt acagatacga ttcgtgcaaa tggtaatttt
    45181 ttgacaatgg aaggaaggtt atcagagaat aaacaaaagc tccagctttc ttatcaagta
    45241 aacacagaag cagaattgaa aacatggctt aacttccgag gaaagggaat agaattgact
    45301 gctgaaggcg agttcatctc tccagcaaaa aagcggaatc tttataattt tgaccaagaa
    45361 gcttacttca ggaaccatag aatttctgga cggttccaaa ttcaaaagat tgaacagatc
    45421 accatgcaaa atcactggcg aaactggctt cagagaaaaa gaggatcttt tatctccttt
    45481 gtccaatctg aatttccgca aaaaacaagt gtatatatta attctttatt atggggctat
    45541 aaagatgcag gattcagaga accagaagaa atttttaggg agagtggttt gctgcatctg
    45601 ttcagtctat cgggtctaca catccaattt tatttagggt ggctgtatta tttgtttcga
    45661 cgtatcggat ggccactaca cgtcagtatt attccgttga gtctactaac tatctgttat
    45721 gtttctattg caggaagttc tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga
    45781 ttgctagtca aattgctgaa taagcattat tccaccatgg acttatttgc agttgtcttt
    45841 tggcttcttt tactatttga tcctcgattt ctttttcatg cgggtggaca gcttagtttt
    45901 ttcatgagtt ttttgtttat cctgatttct tttgatggag attggttgaa aaaaacggcc
    45961 tctcacgtcc tgtttactat gatcacgatg ccgttgattg tatggcattt ttatgagtgg
    46021 cctattttag gtagtctttt tacattactg attgcaccgg tattcaagtt tctttttctt
    46081 cctggtgtgt tatttctcac actcttcaat cgctggctgc cggaaacttt acttttgctg
    46141 atagaagagg gattaatctt atttgagcga ataatcgatt tttcttcagg gtcgtctctc
    46201 attataggac gtttgcccct tgtgctatct gggatgtata ttttcggatt actgatttgt
    46261 atggataggt tgaaagaaca acctgtgaaa cacttgtttt atgttggtct tttttctttt
    46321 atttttttga ctttgccatt tttacgcttt tcttcaacga tcgcttttat cgatgtcggt
    46381 caaggagaca gtatcttttt gcaaagtcct tttcgaaaag aaacgatttt gatcgatact
    46441 ggaggtcagt tacactttga aagagaaaag tgggcgcaag gtatgatacg tcctcctgct
    46501 gaaagaaata tcgttccata tctaaaaggt caggggataa gtgtaatcga taaactcatc
    46561 ttgacacacg acgatacgga tcatgtggga gaattaccca cgttatctca gcattttact
    46621 atcaaaaaaa tttatatcgg ttggggcgct ggacgaaatg agccattaca aaggcattta
    46681 tctgaagctc aaaaaaatgg tactgagatc attgaaatca aacatgggga caggatcagc
    46741 ggttattatg atctttatgt attgactcct tttgaaaagg gagagggaag aaatgaagat
    46801 tcgattggtc tatggatgga atataacaat aggcgctttt tatttttagg agatttgaat
    46861 caagcaatgg aaaaacaatt gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa
    46921 ttaggtcatc acggtagccg tacgtcaagt aacacagatt ttctttccca tattgaagca
    46981 aaacatggga ttatatcctg cggcgtaaat aatcgttatg gtcacccgca cagcgaagta
    47041 ttggagacac tagaagaaaa tcagataaaa acatggcgaa cggatcaaca aggaatgatc
    47101 acctatcgct ggcatccagt ttttcatcct catgggctag tggaaacaat gatagactag
    47161 taattctcat ctgctcatgg taggataatt tttgaaagtg gtgagtaatt tgagtataca
    47221 agcagagtta caaaaaatac gtaaagaaaa acttgcatct tgttacttga ttttaggaac
    47281 agaaaagttt ctccaagatc aagttcggac agaaattgtc aaaaaaatcc aattagaggg
    47341 cgaagatgac ttaaattttt taagttttga catggaaaat gcaagtttag atgaggtagt
    47401 agctgaagca gagacgttgc cgtttttcgg agatcaacgg ttagtattcg tagagaatcc
    47461 ttatttttta acaggtgaaa aagtaaacaa tggaatcgaa caaaatactg atttattgac
    47521 ggcttatttg aaagaaccat tagaatcgac tgtattagta ttctttgcgc catatgaaaa
    47581 gttggatgaa cggaaaaaag taacgaaaca attgaaaaaa acagcaatta tcatcaatgt
    47641 ccaacagttg aatgaaaaag aagtacgtca atatctgatg aataccttag agaattcctc
    47701 aatcaaaatg gaacgaagtg caattgattt attcttgagg ttgaccgact tagatttatc
    47761 caaaatgatg agagagttac agaaattggt cctttatgga caaaatcaac agcaaatcac
    47821 ggtaagagaa gtagaagaat tagttcctaa aacgttagaa cataatattt ttgacatgac
    47881 ccaatatatt ttaaaaggga agacggaaca agctttgcgt ttatacgaag atttagttat
    47941 gcaaggggaa gaaacaatca aaattaatgc gattttgctt tctcaattac gtttattttt
    48001 acagacaaaa tttcttgtaa agattggtta tcagcaggca aatattgctg aaacattgaa
    48061 aatccatcca tatcgtgtaa aacttgccat gcaggaagta aaaaaattcg atgaacattt
    48121 gctggtacag ttgtttgatc aattagttga gatggattat caaatcaaaa cgggacaaat
    48181 cgaaaaagaa ttaagttttc aactattcgt tttgcgcaca gggcagttgt taagaaatcg
    48241 ataagaagaa agacgagggc aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg
    48301 acaaataaaa aaatcggccg aagccgattc ttttatttag cgattttttt gcttaaacga
    48361 gatttgtcgc ggttagcttt gtttttgtgg attagacctt ttgattcagc catatcaata
    48421 gctttaacag cttctttata taacgcatct acgttgtcag cacctgaagc tacagcatct
    48481 tcaaattttt tgattgcagt acgcatagcg cttgtttgag atgaattttt cacattagcg
    48541 ttttcgcttg tacgaacacg tttgattgca gattcaatgt ttggcattag tttcacctcc
    48601 gataacttaa gttcttacgc gtgttaccgc ataattcaac attcattatt atacctaaag
    48661 gcagcgtgct ttgcaatatg aacatgacaa gtttttttcc ttaacagtct tttattagga
    48721 ttttttttca gtaaaaacgg atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg
    48781 gaggcaatag cgtcaaacca aactagattt ttatttatct atttaaacaa agtttgaatg
    48841 ggaatgtttg gtactaagtt attatataac aaagagaacc gtttgcaaag ttttttttga
    48901 aaagggatac gattccctgt tgttctttgt ttttctatta agaaactgca gttattttat
    48961 aaccagtatc ctttgatcag taaaggctat tctggtgtac cgattatttt aatgtattca
    49021 tcgatatttt ttatcaacat tttttttatg accaactggt tccgacggtt ccatttgcca
    49081 cttacttcca gcacatattt atttaggggc aaacgtaaga tatattttgc caaatagcga
    49141 tctttaagca ggccattgat cacacggtcc tcaagctgca agttgatccc agtcagcatc
    49201 attggctgtt cttgtaaaac gtacgtatca attaaaagac cttcaaaagt ttccacaagc
    49261 gtcttccttt cttttcaaag taacctgaaa acaggcacta attcttccat tttgatattc
    49321 gttgaagtgg atgcgatcat tctttctttt gtccactgta atctagtata acaaaaaaga
    49381 gcagaagagc caaaaagaaa aaagagcatc gaattctata ggaagtctca ttggcacggc
    49441 ctaaattatt acaaaacatt gattaaaaaa agcccctgca tcgcaggagc atcccctata
    49501 tcgttttaat aggtcaatca aaaagcagta tcaaacacat tttgtatcaa atcaggaaat
    49561 aatagataag ctaagcccag aatcaaaagt accgctagaa gaaaccagcc gattgttcct
    49621 atgaaatact ttaatttttc gaacattgta tcacctcgtt gtcagtatat cacggatcag
    49681 taaattgggg gtgttaagaa tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc
    49741 aaatacttgt aagatacagt aagtgatacc agaagcaatg accggtccgg cggcgattcc
    49801 tcttaagaag acaacaccta aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc
    49861 agaagcaatc aatcctacac ccttggaaga taagacagcc actagcccac cgcaaaaaac
    49921 agctacccag ccaatagggg atttaaaggc ttctaataga tcacgtagac cgatttctcc
    49981 tgttgcgata gggattagaa tagccgctgt gatgatcgtc accccaatat tgattccttt
    50041 gccttgaagc caagggaaaa aggaacggga ggctggtatg agcttcataa tcaaaacaaa
    50101 agctgccgct atcatcagac tttgattttt agctaaaatt gctacaagta aaataattcc
    50161 taaaaaaagc caactttcca tgaaatatat tcctcacttt cttcgaaaca atcataacat
    50221 gtttttagaa agttacaaaa gtaggaattc atccttcaag acctattcat aagctgtttt
    50281 tttcataaaa taaacaaaat cataaaaaaa cactttgctt atttgacaga agacagccgc
    50341 gctttgtata gtggacaaga cttacatttt tttgaagaat cagaaagatc aggtaaaggt
    50401 cttagtaaac gcaagccatt cagaataacc aatattgtgc ttccttcgtg tcctacaact
    50461 ccaagaggta gatttaaaaa ttgcaggaag ttagaagcaa tcaacaagag aataacaaga
    50521 atcgaaaaaa taatattttg tttgatgatc cgccgcattt ttaaagatag ccgatgactg
    50581 tagacaaatt tatttaagtc gcttttcatt aagacgatgt ctgcgatatc catagcggca
    50641 tctgtccctt gccccatagc gacacctaaa gaagcggctg ctaaagcagg cgcatcattg
    50701 actccatcac caaccatcgc atttacttgg taaagttcat tctctttttt gactagttgt
    50761 gttttttctt ccggagtaca gcttgcatag taatgttcaa tccctacttg ttcagcaatg
    50821 gcctttgctg tgccagaatg gtcgccggtt atcatacttg tatggatgtt ttgggattta
    50881 aagtaggaaa ttacttgttg ggtatttgct tttggaatat ctagcagacc taaaacagca
    50941 attaactgct gatctttaga aagataaatc acggttttgc cttgattttc caaacgttcg
    51001 atcatttccg caatctcttt gctgattatc atcgtctcag gatcatatgc gtgcttgcca
    51061 actttccatt gcgcacctaa ataggtagtt tgtaatccaa aaccagtaat ttcttctatt
    51121 ggtaagtatt ggatttcttc aggtattgtg caatcgaaat attgcaaaat cgcatgagca
    51181 agtggatgcg tcgttttttg ttccatagca acaagaagtt gttgtgccaa atccttttca
    51241 tcaaagaaaa agctgtcagt tacaactggt tttcctttag tgagcgttcc tgttttatca
    51301 aaggcaatcg cttttaattc agaaagcttt tctaaatgga taccgccttt gattaaaatc
    51361 ccattttttg cagaatttga aagagcagct agagaagctg gtgtagcaga tgcgacaagc
    51421 gcacaaggag aagccacaac taataatacc attcctcgat aaaagctttc atcccaactc
    51481 caacctagga aaaagtgggg gagaaggatc attagaggaa cagcaagcaa aatcaatttt
    51541 acataattat tttcgattcg ttcgataaat gaagctgttt gagttggcgt attctgcgct
    51601 tcttctacta attggataat cttagcaaag acagtttcgg aactcgtttt tgttactcga
    51661 atcgtgatgg gatttccttg attcagcgtt cctgcataca tctcatcgcc taaatatttt
    51721 tctacaggca cagattcacc gcttaatgca gactcatcga tcgttgcctg tgtgctttct
    51781 aaaaagccat ctatcggaac agctgctcct ttagcgacaa ataccaagtt atccaccttt
    51841 agttgagaaa catctacttc ttgcatttgt ccattttctt ttaataattg ggctttttgt
    51901 ggttgaagat tcatcaaagc agtaatttct ttttgacttt tattagttgt gtattcctct
    51961 aatgcaccgc ttaaacaaaa gatgaatgtc aacattgctc cttcaaagta attaccgatc
    52021 aaacaggcac caatagcagc taaagccatc aataaatcca cattcagtgt ccgatcattc
    52081 cacaattctt tcaagccttc cgatgtttgt ttatatccac cgatgataat ggcactgata
    52141 taaaaaagtg gggtgatggt aagagagaat cggtcgaaga taaaaccgaa gatcataaat
    52201 aaaaggcagc cgattgttgc tgcaaaagct tttttctgat tagtcatcgt tattagacct
    52261 ccttgtcaaa acaaggatag cataataaaa atgtaattga taataataac agctaaatga
    52321 gaacgataat ggttatcatt tggtgattaa gcttgatgtt gtttttatta tttataatga
    52381 ttattattaa agaaaataaa aaaccagaac atttctcaaa taagagaagt gttctggttt
    52441 tttctacatt gcaataaacc aataaccaat caaaatgata ccaaggataa tacgatacca
    52501 gccaaaagcg gtaaagtcgt ttttcttcaa atagcttagt aagaatttga tagctaagac
    52561 ggaaaccaca aaagatacga atgttcctac aagaagaaca acagtttctt ccattttgaa
    52621 tgaattccct tcagctaaat atttgacgat cttcaagccg cttgcgccaa acatgacagg
    52681 aatccctaag aaaaatgaaa actctgtagc gacaaaacgc gaagcaccaa tcaagataga
    52741 tcctaggatc gttgcgccag aacgggatgt tccgggaaca agtgccaaga cttggaataa
    52801 cccaacaaga agagctgctt ggtacgtaaa gtcattcaga gaagtccaac gaggtgtttt
    52861 gtttttgttg cgtttttcga caataataaa ggcaataccg taaacgatca aaacaatggc
    52921 aactggtaag aacttgtgga aatttgcttc taaccaatca tccaaaggca aaccaatgat
    52981 gatggctggt atgcaagcaa cgatcacttt aaaccaaagt gtccacgtat cttttttttc
    53041 taccgttgat ttacttggag aaaatgggtt taacttgtga aaataaagaa cgacgacagc
    53101 caagatcgcc cctaattgga taacgacatt gaacatcgac ataaattgtg aactggcatc
    53161 cagtttgatg aattcatctg ctaggatcaa atgaccagta ctactgatgg gcagccattc
    53221 cgttattcct tcaataatac cgagaatcac tgctttgata atatttgcaa aaaacataaa
    53281 ttccttcctt cccaattaag atacatctta tagtataccg ttattttttg agaaacccaa
    53341 tctgtttttt aatattaaga aaaacttgag aaataaagca gataagtaca cgaagagaaa
    53401 aaagaagaca aagccctcgt tcagactttg ccttttatga ttctctggta aaaattaaaa
    53461 tatccccatt atagaaacga gtcgcgacta tgtgttttcc cgttatcgat ataagacgta
    53521 tcattgatgc cgtggataga aaatcgaccg tttgcataag tgacctttgt tacgctgcca
    53581 tttaaaagcc cagcacgaac aggctgttta ggatcgatca gattaagcaa aaaggcgatc
    53641 gtcaaaccat gagatacgac taaaacattt ccaccaccat ttttttcgca gtgatgggcg
    53701 atatcttcaa atcctgtcca tacacggtct cgcaatgttt cataagtttc cgcccaccca
    53761 gcggtatcta agttgtatac agcattagca atttgttcaa aagaaacttc tgtggtaaac
    53821 atttcatcat atgttttaaa attcaataca cgagggatca caccccacat ttccatgtca
    53881 tatccacctt caagagaccc gaaacaccat tctctaatcc ttttttcaat aaaataagga
    53941 atttcttttc ccttagaatg ttctcctaga ataatacggg cagtttcgat tgcacgacca
    54001 ctgtcactag aataagcaaa tgaaaagtcg acatttttta acccgcgacc taaataatga
    54061 atgccttctt gtccttgctt tgtgaggggt gtatcacacc agccttgtac tcgttcaatt
    54121 gtattgaaca tcgtttttcc gtgtcgtacg atataaagtg tagtttctgt cattttattc
    54181 tcctcctaag tcgttttaac gattgaaaaa aggatttgtc cttttttcct gttcaatcgt
    54241 cgttgcatcg ccatgtcctg gatagactgc aaattcatca ggtaatacaa acagctgggt
    54301 ccgaatacta tgaagtaatt gttctaaatt ccctgtatac agatcggttc taccgatact
    54361 tcctctaaac agggcgtcgc cagaaacgac aaaatcatca aaaataaagc tgacgcttcc
    54421 tatagaatgc cctggggtag ggacgacgcg aaaagacatg tttcctaaag tataagtttt
    54481 catttcaaat tcatattctg caggcgagac aataacatca gcaatatcat catgtctacc
    54541 gagtccagaa agattcaaaa tcggatcacc tagccatttt tgctctagtg ggctgacata
    54601 aactgggatt tgataatacg cgcgtaaagg ttccactgca ccgatatgat cgtagtgagt
    54661 atgggtaagc aaaatcgcta ccggctgttg gtttgttttt ttgatttctt gtttgattcg
    54721 ttccgcatct tctccagggt caatgatcaa aagtgcttct tcgttgtaga ccaaataaca
    54781 gttttcttca atcattcctg tttttaatct ttcgatatgc atgtgcattc ctccttgata
    54841 gccaaaactt ctttcatcca ttagtataac gcattcattg ctaggaaaca aaaacaggta
    54901 cttatttctc tttacttatc tgaattatca gactatatga aaagtatttg gatattctaa
    54961 agagaaggaa agtaagtttt catagcattt taatatgtcc ttgttacatt agattcatcc
    55021 aaaaatccaa attctatatc ctatatccct gcctaatcag cagggtgttt ttttatgttt
    55081 ggaaagagag ctctttttgc taaactaggt tttttcaggt aatcttagag agaaagaggt
    55141 ggtggaaatg atcaaacagt caaaaatatc tgtgcggcac ttagtagaat ttattttgcg
    55201 acgtggaagt atcgacaatc gtaaaaaaag taaccatact gcattagaag gagcgagaat
    55261 ccaccgcaag ctccaaaaag atgcgggaga aaactatgaa aaagaagtct ttttaaaaac
    55321 aacagttcaa ttagatgaat attacctgat cgttgaaggc cgtgcagacg gtattttcaa
    55381 aagagacggt atttattata tagatgaaat caaaacctcc gaaccacgat ttgaagattt
    55441 agaaccagaa caagtggaac ttttctttca tcaagcaagg gtgtatgcct atatctatag
    55501 tcaagaacat gatttacaag aaataaatct gcaattgact tacttccaga cggcagaaga
    55561 agtgatcacg agaaaggttg aacatcagac aagagagcag ttagaaactt tttttaaaaa
    55621 gctgactgaa gattataaag aatggcttgt ttttcaagaa aactggcgca ctgtacgcaa
    55681 tgcctctttg atggctttga aattccccca tgatgagtat aggaaaggtc agcgtgaact
    55741 agcggtagct gcttataaaa cgatccgtac gaaacagaaa ttgtttgtag aagcacctac
    55801 cggaacagga aaaacaatct ctacgttatt ccccgctttg aaagctgtag gggaagaaga
    55861 gggagaaaag atcttttatc taacggctaa aacaataact agacaagtag ctgaagatgc
    55921 tatgacagca ttaaaagata caggagctga agtaaaaagt gtcactttga cggcgaaaga
    55981 caagatctgc tttttagatg agacgacctg taatccagat cagtgcccat atgccaatgg
    56041 ttattacaat cggattaatg aaggtttatg ggatcttttg aatcatgaga atcagatcac
    56101 tcgtgaagtc atcgaaactt atgcaagaaa gcatacactt tgtcctttcg aactatcatt
    56161 agatgtcagt atctggtgtg acgtaatcat tggggattac aattatttat ttgatccaac
    56221 tgtttattta agacgttttt ttgaagatga aaaaaacgag gactatctgt ttttgattga
    56281 cgaagcacat aatttggtga atcgttcccg agagatgtat tcggcagaac tatcttatga
    56341 aaaaacgaaa cgaagtaagg aagctatacc aaaggaattc aaaaaacttc atcgccgttt
    56401 caacaaacta ttaaaagaat ttgattcgat ccgagaaata gcaaaagaag atcattggga
    56461 ttatcatcat caaaaagcac cggctgaatc tttagtaaag gcaggttatc aattaagcga
    56521 aaaaattaaa gaatggctgg cagaatttcc tgagcaccca tcacaagaac aattgcttcc
    56581 ttattatttt gatttgcttc attttttgaa ggtcagtgaa ttttatgatg atcactacga
    56641 aacaacagtc gaaaaaacgt atcgcgatct gatagtaaaa gagttttgta ttgatccaag
    56701 cttgtttctt gagcagtcgt tggataaagg aaaaagcagt attctttttt ctgctagttt
    56761 ttcaccactc tcttattatc aggaaacact ggggggacaa aaaagtctgg cttacaaact
    56821 gccgagtcct ttcccagaag gaaaccagca agttttcatc gcaaattacc tagagacgac
    56881 ttatcgaaaa agggaacaca gtctggcaaa attagtagag acgattcatg cttttgctga
    56941 tggaaaggtc gggaattatt tcgttttctt tccttcttat caatatttag atcttgcggt
    57001 ggaagcattc agacagcaat atcccgacag caatgtgcta atccaagaaa cggacatgaa
    57061 tgaggaagaa cgcgaacgat ttttaacaaa atttcaaaca aatcccgctg aaacattgat
    57121 tggattttgc gtacttggcg ggattttttc agaaggaatc gatttgagag gggaccgatt
    57181 gatcggcagt atgatcgtag gtgtaggttt gccgcagatg aatcatgagc aggaactgat
    57241 caaatcatat tatgatgaga aggaacacct tggatttgct tacgcttatc agcttcctgg
    57301 aatgaacaaa gtcttgcaag ctggtggtcg agtgattcgt ggcatggcgg atcaaggaat
    57361 cgttgtattg gcagatcaac gattttctag tttttcttat cgacgtttat tcccacaaca
    57421 ttggcaaaca gcaagagaag tacgaagtgt tggggaattg gaagaaggaa tacagcgttt
    57481 ttggttatca aaagaagcag taaatcaaaa aaacgaggaa tgacagacgt cagcctcgtt
    57541 ttttgattaa cgatagttag tgaattgcaa ctcgattggt aagtcaagtt tacgtaataa
    57601 agcaatcaca gcttgtagat catcacggtt cttacctgtc actctaatct gatcttcttg
    57661 gatttgtgct tttactttca gtttttcatt tttgatagct gtagtgattt tcttcgcgtt
    57721 ttcacgatcg attccgttga ccaaatcggc agtttgtcga gctttgccac ctagagcgtg
    57781 ttctgattcg gaaaaatgga tatttttgat tggcacattt cttttgatca gcttaccaaa
    57841 taatacatct ttgatctgtt cgattttgaa atcatcatcg ctcaatacaa ctagattgct
    57901 gttctctaat ttgatttcta ctgtagaatc cttgaagtca aagcgattgg acaattcttt
    57961 tgttgtttgc tgaatcgcat tttttacttc ttctgtattg acttctgata caatgtcgaa
    58021 gctagcatct tttgccatag gaaccctcct gatatacata taaatattta ccatacatct
    58081 atcttatcat aggattaggg cagattctta cctgtttgct aaaattcttc tcatttgagt
    58141 tcgaagtatt ttattttaat agataaactg ttattcttac atttggaata ccaaagtagg
    58201 ggagaggtgc ttgtgagtaa aattatgact gcgtatcata aaaatgaaag attaaagaaa
    58261 atagtggtta ttttgataac cggattgacc gctgcggtcg ctttaaatta ttttttgatt
    58321 ccagccaatg tcttttctgc agggatgaat gggatcgctc aaatcatttc ctcgctttta
    58381 tatgaatggt ttcatatcaa gatagacaca ggaacattta tttttctttt gaatatccct
    58441 gtgtttgtat tagggtttct caaagtagga aaacgagcaa cgatccttag ttttgtgaat
    58501 gttgtatgtg tatcggtgat gacgatgctg cttccagtcg gacagatcac tgataatatt
    58561 ttgatgaatg ccctagtagg cggtgtttta ttaggtcttg gcgtaggatt atctttaaaa
    58621 atgggcttta caactggtgg gatggatatc atctctcttg tactttcaca aacaactgga
    58681 aaaacagtcg gaaactacat gctgattcta aatggtatca ttgtagtcat cgcaggcttc
    58741 ttctttaact gggaaagtgc cttgtatacg attatttcca tttatgcaat gactcaagta
    58801 attgatgcca tccacacgag tcatcaaaaa gtaacagcaa tgatcgttac cgtcaagcca
    58861 gaagaggtaa cagaagaact agcaaaacgg atggtacgtg gaatgacatt actgccgtct
    58921 gtcggtggct attcaaaaaa acaagggaac atgatcatga tggtcatcac ccgctacgaa
    58981 atgtatgatc ttgatcagat cgttcatgaa atcgacgacg atgcatttat caatatttta
    59041 ccaactcatt cagtatttgg ccggtttgca aatgaaaacg aacaaaaaat gtatcgaaca
    59101 actggcgtat tgccagaaat aaaaaatcgt tcacaaaaaa aatgaggaat caggtttatt
    59161 ttagaataaa tttaatctat tacatctaat aagaacattt ttataaattt aaacgagaat
    59221 cttacttcta aattctcatt tacaagcagc taaaaaaaga gtatgataaa taaaaatcgt
    59281 gttaaggagt gtcgtacgat gagcgaagca aaccaagaac ggtctggaca agaaatagaa
    59341 ctaatcaaag aacgtattct tgctgccttg gaaatggtga ttgatcctga attaggaatc
    59401 gacatcgtca atttaggctt gatttatgat atagaattca atcctgaaaa tggagaaaca
    59461 gtcattaaga tgactctaac aactatgggc tgtccattag cagatatttt aacagaatct
    59521 atccatgacg cattaaaaga agtgccagaa gtaacgaaag cagaagtcaa actagtctgg
    59581 tatccagcat ggacgacaga taagatgagc cgttatgcac ggattgcgtt ggggatacga
    59641 tagaaatctt ggctgactag ctatgagaag caaataggaa aaacaaaaaa gccttttatc
    59701 ctttctagaa gaaaagagat aaaaggtttc tttgtttata aaattttgtc tgctatatta
    59761 taagttaatt aaataaatgt gttctattga taaaggacat tcaaatccct ttccttttgg
    59821 aatccttctt ttttacatca gtttgatttt cgtatagtat tctttctcat cttcacgata
    59881 aatcgcagcc ccattttttt gttgtgcttt aagactgcca agattttttt tatttacaga
    59941 caaaagtgcc tcatcaatgc cgattttttt tgcctcttgt agtactaatg ctaatccttg
    60001 tgtggcatat ccttttttac gataattagg ggagatgccg taaccaatat ggccagcgcc
    60061 gtttcttaat gtttcgttca gtttatggcg caaattaaaa attcctacat actcatgttc
    60121 atcactttct aaaataaaga cggttgcggg aacgtaactc tcaggaagat cgattcctaa
    60181 agacgttttt tcgcattttt ttacataatc taaaaattca gcaaatgtat agccataagc
    60241 attgttgata aatccactct catttggtcc aaagctagtt tgtagctgat aagctttctt
    60301 taaatctgct tcccatagtt tgatcagttt catcgtattc acctctttaa gtaaccttat
    60361 tcatttgttt tctactatag cactattgtt gtaaatagcc atgcctattt ttatttattg
    60421 tgtcatatcg tattaagaat catcgaacaa tacaaatatg aattacaata aaaaaattat
    60481 ttgaagttcg ttcattcgtt acttatgatc tctagaagaa agaaaacgtg aattacttca
    60541 gcgtctagaa ttccagaagg atagtaatca acagaagaaa taatcaatat ccaaatgaaa
    60601 gaagatagct gaatcgagaa aaagaggaaa aaagaaatga agaaaaaaat aaaatagtta
    60661 ctaatcccag agtcgttcgt ttaacattga aatcgatcat atggataaaa cagatttttt
    60721 caccaaccct caatagatga tggagttgct cggatgaatt atttgtgtag atggcataag
    60781 ggagggcgta cagaaatgaa aaagaacaaa aatatgttct tgacaaaaaa cacatgtaat
    60841 cctaaactaa aagatgtgat gcggctatgg cggaattggc agacgcgcta gcttcaggcg
    60901 ctagtgaggg tgacctcgtg gaagttcgag tcttcttagc cgcataattt gtttttttat
    60961 aaagagaagg tacacctgga gcgatgagaa agaaaataac atattatcta aaagaatata
    61021 ggaaaaattt taaacaacgg aaccagattc aaataaatca aaaaaaattt gtgtgaaggt
    61081 gggacagttt aaaacctaat agattgattc aaatagtaga tttatagatt ctgatacaag
    61141 aaatactggc aaacgatagt taaggaataa agactaaact taaactcaaa aagaggtcat
    61201 gcgaaagaat aaatcgcatg acctcttact atattttgaa tgtgtttaaa cgttcaaata
    61261 atgaatctta gtaccaaccg tttgcttccc agaatgcttt cgccgcttcc caagaaccat
    61321 aacgtgaagt aacatattgt tctgctactc tttcttggtt tgcagcagag tagtcaccat
    61381 ttaagtaaga agaatctaat tggtaacggc cgatgtaacg tccgttcgtt gctgtgtaag
    61441 aaccgcttga ttctttttgt gcgatccatt cttttgcaga gcttgtactt gctggagtag
    61501 cagcagtttc tgttacagca ggagcaggtt gtgtttcagc aacaggcgct gcttgtgttt
    61561 ccgtttgaac cgtttcttgt acaacaggtt gttcagcttg aacaggttca gcttggactg
    61621 gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct tctgttggga
    61681 ttgttaattg ttgtcctgag tagatcaggt taatatcaga aattgaattt gattctgcaa
    61741 tggcattgat caaggagtta tcaccaacgt atttttgaga aatcgttgat agagtatcac
    61801 ctgattgaac ggtataagct tcgtccgcat gagcagtcgt tcccatgaag aatgcagcgc
    61861 cggcagccaa agttgttcca aaaagtaaag ttttaagtga tgtcatgaaa aatctccttt
    61921 attcgttaaa aagttttatt tgttgtgttc aacgaggaat actttaacac gtgaaaatat
    61981 ttcataggta aaagaagcat gacaatttat gacaaatcca cgttttttgt aacagaatga
    62041 tgttcgctcg atgtgaaaaa tgatgaggaa tttcacataa tgcagaaata atgggattag
    62101 aacaggtgtt ctgatgagaa aagaaatgta taaataactt gaaagaaatt gcttttgttc
    62161 atcattttat ttacatattg cgtatatttt ttgtattttt gcttgagatg ttacaataaa
    62221 agaaaaagga ggcggttcca atgagtaaaa gataccagaa catcatggta gcagttgacg
    62281 gatcaagaca atcgatcaaa gcgttcgctg aagcccttga cttagcaaag gacaatgaag
    62341 cccacttatt tatcgtgtca atcatcaaca aagttgagct gacccatagt gcctatgcct
    62401 tttcaaaaat ctatgcagat gaaaaacaaa gaacagaagt agccatgctg aaaaaaatca
    62461 atgatgccaa agagtacggc attgctgaga tccacgcaat agttgaaact ggagatccaa
    62521 gaaatttgat tgccaatgtc atccctggac aagaaaatat tgatttgatc gttatgggag
    62581 cgacaggaaa aggtgctata caacaagcat tagttggatc gaccgcttct tatgtcgtat
    62641 cacatgcccc ttgcagtgtg ttggtcgtga agtaatgaga taagggagga atagaaaatg
    62701 gttcgtcctc aagaagtccg tgcgccaaaa gaaaaaatag aaattttagc aattattgaa
    62761 gacggcacac aaacaaagaa gggatactcg atcgctttag taaagtggaa aggaaaaaaa
    62821 ggtgttgctc tgagatggga tggagataac caacaagata aaggattccc tgtcacagct
    62881 aacggttatc atccagcgtg gtttgttctg cctgataaat ttatggaatt atacagctat
    62941 gattatgcaa gagccgcagc atcaatcaaa gcattagata aattaacaga agagcagaat
    63001 gaaatggagg aaaaataaaa aagacgaacc aatcagcctt tagaaaactg attagttcga
    63061 ggagtaaaaa tgaaaaaagg ttatttggga tgaaactaga ataatgcgta taacttaaat
    63121 aaaacttaaa gcaataaaat ggcaagaggg tgaggcaaat ggaagcagga aaagtattac
    63181 aggaagtaaa agcactatgt gcagataaaa aatatgaaga agcgaaaagc ctgatcgaaa
    63241 agaacaaaga aaatttggaa gaaaagtacc cgatcgcaca agaatttata gaattaaaac
    63301 aaggaacgat ccttcaccga ttcaaacatt tttttggtat aacagaatag aaaaaacgat
    63361 taaagatcgg cagaaatttg ctgcatcttt aatcgttttc tttttaaaca tgcgagggat
    63421 tcaattctga ttcttatata aaaaatagat ccaaataata agaaaaatta ctgaaagcgt
    63481 caattcgatg atgtgtgtta ttaatacaga cgttgtttcc caatgcctaa aagaaaaaat
    63541 ttgataagta aaatatacag caggtaaaga ggccagtaaa actgaaaact tcttttttgt
    63601 ccattttatg taatagaaaa gaatgcttat cataataaaa aaaggaatat aaaaaacaaa
    63661 ttgaccgatc gcgatcatac tattgcctcc gataaataaa gtccatgata caaaataaca
    63721 ctttgtgcga aatggcgcaa gcagttttgt ggatttatcc ggtaaaatct gtatcgattt
    63781 tgaaattaga ggagaaactt gctataatca aagtgaaaga aggagtggga ttttcatgga
    63841 tcatgtagtg ttagaaatcg atttgcattt gatcaataat attcgggtga tttactatgt
    63901 tgtaagtaac agtgtcgaac aacgtgtact gacgaataaa ataaatggta ttttagcaaa
    63961 gaaagacgtt caccgattca ataatggtga aggaagttat tatagtatcc cagtagaaaa
    64021 aattatttat acgacagtca aagtcagaga agatctagat accaaaaaag catatgaacc
    64081 tatttttaca acttattgat tgacagcaga tggaggaaaa aaatgaatcc atatgaacaa
    64141 cttattcaag atttgatcga tggaaaaatc gaaaagattg atgtaaaaag agaagaatta
    64201 atggcttttc gagaagcgtg gctgaagttg gagaatcgta aatatgtggt gggaaaagcc
    64261 tcactgaacg gcaatgtgac ttatcattac gatccgacac gtttatttta gtatgaagta
    64321 ttcagaaaag aaccaaagga ggacgatgca gcagcattgt cctcctttga ttttacaaaa
    64381 gtgaaagttt tacttatttg aatagatttt taaatttgtt tttgacactg tcgatattta
    64441 catcttttaa aagattttgg gctttctctt tataaggtcc taattgttct ttatgttctt
    64501 cgataaatcg ttttgcgcca tcgaaattgc cgttcttaat catttccttg actttttgaa
    64561 ataattcttc ttgattcatt ttgaacacat cctttgctat caacatgatt ttttacatgg
    64621 acaaaacgag aaaaactgat ttatccacac gtcaataata tcaaataacg atcattttta
    64681 ctaaaaaaac actcgattct cgcttctaaa gtaggagaaa aatctccaac ttgggacgga
    64741 tggaatttct ttaactgacc catatactga atatataaca aggaggtaga aagatgaaag
    64801 tgattaaata tttgattgga ctggcggcga ttagtggtat tttgctattt ggactgaaat
    64861 attatactga aggaagttat ggagaaatcc ctggtatact tgatcagcta aatccattag
    64921 ttgaaaaagg agaggtctat gtaaagacac aaaaaccaga ggaagtaaat gaatatggta
    64981 cagcaaggta tgtgcagaaa gctgctgatg ccaatgggaa agaacgaacg gttgaattta
    65041 atggtctttc tgtgttaaaa gaaaatcatt atttgaaaat tagcaataaa ggagcacaca
    65101 tagaaacgta tgaggaagtt cctagagaaa aagttccgga gaaagcatta gcaattattg
    65161 ggtaaatcag tttttgtatt aagaatacgc ccgattttat tattcataat ttaattatgt
    65221 aaactaaata caagtagtaa aaataataca ataatccccc tgcaaaaaga ttgttctttt
    65281 acagggggtt cattttttca gcaagcacat caaattggga tggcagggtt cgaacctaca
    65341 attgcttgat tcagagtcaa gtgccttacc agtttggcta catcccattt attcaacaaa
    65401 ataatcatag cactttccta aaaaaacgca agttattttt cttgatcgga tagttgttgc
    65461 tttactcgta aaaggcggcg tactagtttc ttttctaatc cagcaggaag ggcaatcagt
    65521 tctgctactg acaagacggt gtccaataac tgatattctt tgacaggttc attcataata
    65581 tgatagatgt ttgctaaacg ttcaatatat tcaaagcgag tatactctgt tcgagcaatt
    65641 agaaatttca ataaatcggt ggctttctcg tactcttgat ctgcgtaata aacaagagat
    65701 tgacgataca atttgatttc cagttcattg agggtagcag gtctgcgacg ctcgttccac
    65761 tcattaatag agactttacc ttgaacattt cccttgcagt cacggacaaa aataatcgga
    65821 atttcatttg gatccatttt tttatgtgtg aatttttcca ttatctacgc tcccttcaaa
    65881 ggtttggtat cttgagtata agggattttt gtttgaatta ctagcttttc tccaaagtta
    65941 gcatctgtcc acccattgca gtgaaaatcg ccgaaaaatc gttgatcggt actgctcgat
    66001 tttttacacc atagggatcg ttgacataaa tattttcttt gtcatatcca gtgactacac
    66061 aagcatgaac aagaggagtg actcttactt ctccattatt tgtggtccaa gtcataaaat
    66121 cagtttcatc tgggacttca aaattgatag tcacagaagt ccagacagga tttcctttag
    66181 atagtgcttt tttgatatca tcgagttgag catcggtttt tggaaaagtg tgataatccg
    66241 tttggacgat ttgctgagca agggaggcaa ctgggggaac atagacgacc atagcccagt
    66301 ctccgccact gatatcacca acaaatcctt cattaggatc gccatgagtc ccatctgcat
    66361 tgaaaacagg gacgtaatcc aattgctcag ctaactggtt tttagttgtt tcataaccat
    66421 aaaaagataa aagcatagaa agcgaagtga cttcacagcc attttctaaa gaaggagaat
    66481 caaactggct ctctaatgga acatctagta aaacttctgc tttctctttt gtctttttcg
    66541 ttttttgtgt tgaacttttt tgtgcagtgt tcattgtatg ttctggagaa tggatatgta
    66601 ggtaataact tgtaccgctt aataaaagag cagctgtgcc ccctagaaac aatagttttt
    66661 tgaacgtttt tttcttcatt tgaaatctcc cttttcagct gtttatcttt cctattataa
    66721 atgtattttt attggaaatg gaagtattat attttaatat gtaggaaata attagttttt
    66781 aaggaatatg ttttaatttt ttgaaaaaaa ttcttctaaa tacaacagct gttttaattg
    66841 tgaaaacgaa aacagtacgc tataatgcct gtaaggttga tttttaactg taaataaaaa
    66901 tcaatgagtt aaatctccaa agaaatagca gtggtaatgt ggagaaaagt tccagcagtt
    66961 taggaggatt ttgatgacgg aagaaatgat taatttagga gaacaatatg catgcaaacc
    67021 aattggtttt acaaaaacgg tcattggtga agttgtatca aaaatgacaa actgcgccgt
    67081 ggtcaaagtt gcccaatgtg ctgcagagga ccaagaatta ttagatgaaa aagcaagcat
    67141 ggttgttgca aaatatgata catttgaata aagaaaacaa ttggacgtgc ggcgtgctgc
    67201 aagtccaatt tctttgagaa ggtaaatcag tattcttttc ctattttctg gagaagaaaa
    67261 agcgaggcga gttgtcatgg taacattctt tacggttcta ttgtttttat tcgttgttgt
    67321 gatgttttta tttctttggc tggttcgaaa agaaattatt tatcggactg tgcgaaatcg
    67381 atgggtctac ttggtgatac ccttcttagt gtcactagtc atttggtata cactcatcag
    67441 tcatcctaca gcagatgaat tggcaaaagg gatcttgtca gcaatgattt ttattagttt
    67501 tttgttggac agtagaggaa tcacagaaga aggacttgtt ttgaatagct ttgacaaaaa
    67561 aggtgttcct ttttctgaga tcaataaaat tgtattatat cagccaaaag gttctaaaat
    67621 cgtaaaaatg aattttttcc gaaacggatg gcgaggaccg atgctgaaat tttctgcatc
    67681 attagaagaa ttagttccat ttttgtccca acgcttaaac gatgaggcag agattgatat
    67741 tatgattgat ccagaataaa aacagaggtt gcgacaagat gtttgtcaca acctctgttt
    67801 tttatttcaa ataaaattat ccaaatacgc ggaagcgatc ggcatcgttc atgtattctt
    67861 tttcctcagc cggtgtttct ggtgaaccga atactaattg cgaacgtagt ttccagtttg
    67921 aagggatatt ccattctttt gcaactgctt cgtcaataac tgggttgtaa tgttgcaagt
    67981 ttgcgcccaa tcctttatca actaatgcta cccaagtatt agctgttgcg attccgtttg
    68041 attgttctga ccaatctggg aagttgtctg catataattc aaattgttct tgtagacctt
    68101 ttaccacgtc agtatctttg aagaataata ctgtaccata accatttttg aaaccagcta
    68161 atttgttttg tgtatttggg aaagcttctg ctggagtcaa tgggcgaagt gcttcttcag
    68221 tgatttccca aagtttttca tgtgcatctc cgaaaaggat aactgcgcgt gttgattgag
    68281 cattgaaagc agttgggctt tctttaattg cttctttgat caaagttgtt aattcttcat
    68341 tagaaagtga aacattacgt cctagatgat agattgaacg gcggtttttc aaagtgtcag
    68401 taaaagttgt cataataaaa tttctccttt gatttgcgtt ttgcattttt ttaattgatt
    68461 acgaaatgaa gtatagcacc ttacaaaaag taagtaaaca gatatgctca caaaaaataa
    68521 gcgaagttca aaaaacaatt ttaataagaa aaatcgttat gtaaggattt tcttagttat
    68581 cgctttcatt gttgtgtttt aggaattttt gcttatttg
//
LOCUS       DADVXV010000004        64614 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.004, whole genome shotgun sequence.
ACCESSION   DADVXV010000004 DADVXV010000000
VERSION     DADVXV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 64614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.004"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            14..652
                     /locus_tag="KB969_000211"
     CDS             14..652
                     /locus_tag="KB969_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6868229.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(771..843)
                     /locus_tag="KB969_000212"
     tRNA            complement(771..843)
                     /locus_tag="KB969_000212"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(808..810),aa:Thr,seq:cgt)
     gene            964..1206
                     /locus_tag="KB969_000213"
     CDS             964..1206
                     /locus_tag="KB969_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868230.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(1345..1974)
                     /gene="upp"
                     /locus_tag="KB969_000214"
     CDS             complement(1345..1974)
                     /gene="upp"
                     /locus_tag="KB969_000214"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBB6868231.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(2108..3055)
                     /locus_tag="KB969_000215"
     CDS             complement(2108..3055)
                     /locus_tag="KB969_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6868232.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            complement(3208..4452)
                     /locus_tag="KB969_000216"
     CDS             complement(3208..4452)
                     /locus_tag="KB969_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBB6868233.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            complement(4643..5668)
                     /locus_tag="KB969_000217"
     CDS             complement(4643..5668)
                     /locus_tag="KB969_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBB6868234.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            complement(5690..5869)
                     /locus_tag="KB969_000218"
     CDS             complement(5690..5869)
                     /locus_tag="KB969_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868235.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            complement(5862..6701)
                     /gene="prmC"
                     /locus_tag="KB969_000219"
     CDS             complement(5862..6701)
                     /gene="prmC"
                     /locus_tag="KB969_000219"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBB6868236.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            complement(6694..7767)
                     /gene="prfA"
                     /locus_tag="KB969_000220"
     CDS             complement(6694..7767)
                     /gene="prfA"
                     /locus_tag="KB969_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBB6868237.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            complement(7770..8354)
                     /locus_tag="KB969_000221"
     CDS             complement(7770..8354)
                     /locus_tag="KB969_000221"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBB6868238.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            complement(8460..8929)
                     /locus_tag="KB969_000222"
                     /pseudo
     CDS             complement(8460..8929)
                     /locus_tag="KB969_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            9035..9637
                     /locus_tag="KB969_000223"
     CDS             9035..9637
                     /locus_tag="KB969_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6868239.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            complement(9741..10310)
                     /gene="lepB"
                     /locus_tag="KB969_000224"
     CDS             complement(9741..10310)
                     /gene="lepB"
                     /locus_tag="KB969_000224"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6868240.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(10540..11307)
                     /locus_tag="KB969_000225"
     CDS             complement(10540..11307)
                     /locus_tag="KB969_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868241.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            complement(11304..11783)
                     /locus_tag="KB969_000226"
     CDS             complement(11304..11783)
                     /locus_tag="KB969_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBB6868242.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            complement(11908..12645)
                     /locus_tag="KB969_000227"
     CDS             complement(11908..12645)
                     /locus_tag="KB969_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBB6868243.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            12806..14206
                     /locus_tag="KB969_000228"
     CDS             12806..14206
                     /locus_tag="KB969_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBB6868244.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            14429..15781
                     /locus_tag="KB969_000229"
     CDS             14429..15781
                     /locus_tag="KB969_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBB6868245.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            15774..16472
                     /locus_tag="KB969_000230"
     CDS             15774..16472
                     /locus_tag="KB969_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBB6868246.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(16534..17685)
                     /locus_tag="KB969_000231"
     CDS             complement(16534..17685)
                     /locus_tag="KB969_000231"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBB6868247.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(17698..18135)
                     /locus_tag="KB969_000232"
     CDS             complement(17698..18135)
                     /locus_tag="KB969_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6868248.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(18150..19916)
                     /locus_tag="KB969_000233"
     CDS             complement(18150..19916)
                     /locus_tag="KB969_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBB6868249.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            20180..20857
                     /locus_tag="KB969_000234"
     CDS             20180..20857
                     /locus_tag="KB969_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868250.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            20860..21987
                     /locus_tag="KB969_000235"
     CDS             20860..21987
                     /locus_tag="KB969_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868251.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(22187..22627)
                     /locus_tag="KB969_000236"
     CDS             complement(22187..22627)
                     /locus_tag="KB969_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6868252.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(22638..24671)
                     /locus_tag="KB969_000237"
     CDS             complement(22638..24671)
                     /locus_tag="KB969_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6868253.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(24673..26376)
                     /locus_tag="KB969_000238"
     CDS             complement(24673..26376)
                     /locus_tag="KB969_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6868254.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(26470..27420)
                     /gene="manA"
                     /locus_tag="KB969_000239"
     CDS             complement(26470..27420)
                     /gene="manA"
                     /locus_tag="KB969_000239"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBB6868255.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            complement(27459..28484)
                     /locus_tag="KB969_000240"
     CDS             complement(27459..28484)
                     /locus_tag="KB969_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6868256.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(28693..29562)
                     /locus_tag="KB969_000241"
     CDS             complement(28693..29562)
                     /locus_tag="KB969_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBB6868257.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(30266..32158)
                     /locus_tag="KB969_000242"
     CDS             complement(30266..32158)
                     /locus_tag="KB969_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868258.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(32155..33882)
                     /locus_tag="KB969_000243"
     CDS             complement(32155..33882)
                     /locus_tag="KB969_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868259.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(33898..34548)
                     /locus_tag="KB969_000244"
     CDS             complement(33898..34548)
                     /locus_tag="KB969_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6868260.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            34752..35048
                     /locus_tag="KB969_000245"
     CDS             34752..35048
                     /locus_tag="KB969_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6868261.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            35240..35860
                     /locus_tag="KB969_000246"
     CDS             35240..35860
                     /locus_tag="KB969_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBB6868262.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(35952..37118)
                     /locus_tag="KB969_000247"
     CDS             complement(35952..37118)
                     /locus_tag="KB969_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6868263.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(37130..37483)
                     /locus_tag="KB969_000248"
     CDS             complement(37130..37483)
                     /locus_tag="KB969_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6868264.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            37611..38633
                     /locus_tag="KB969_000249"
     CDS             37611..38633
                     /locus_tag="KB969_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBB6868265.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            38652..38813
                     /locus_tag="KB969_000250"
     CDS             38652..38813
                     /locus_tag="KB969_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868266.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(39072..39506)
                     /locus_tag="KB969_000251"
     CDS             complement(39072..39506)
                     /locus_tag="KB969_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868267.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(39616..41475)
                     /locus_tag="KB969_000252"
     CDS             complement(39616..41475)
                     /locus_tag="KB969_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6868268.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(41593..42753)
                     /locus_tag="KB969_000253"
     CDS             complement(41593..42753)
                     /locus_tag="KB969_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBB6868269.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(43060..44484)
                     /gene="araA"
                     /locus_tag="KB969_000254"
     CDS             complement(43060..44484)
                     /gene="araA"
                     /locus_tag="KB969_000254"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBB6868270.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(44500..45198)
                     /locus_tag="KB969_000255"
     CDS             complement(44500..45198)
                     /locus_tag="KB969_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6868271.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(45155..46816)
                     /locus_tag="KB969_000256"
     CDS             complement(45155..46816)
                     /locus_tag="KB969_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBB6868272.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            47034..48434
                     /locus_tag="KB969_000257"
     CDS             47034..48434
                     /locus_tag="KB969_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBB6868273.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(48686..49765)
                     /locus_tag="KB969_000258"
     CDS             complement(48686..49765)
                     /locus_tag="KB969_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6868274.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(49851..50810)
                     /locus_tag="KB969_000259"
     CDS             complement(49851..50810)
                     /locus_tag="KB969_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6868275.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSKKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(50822..52333)
                     /locus_tag="KB969_000260"
     CDS             complement(50822..52333)
                     /locus_tag="KB969_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6868276.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(52355..52918)
                     /locus_tag="KB969_000261"
     CDS             complement(52355..52918)
                     /locus_tag="KB969_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6868277.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(52924..53787)
                     /locus_tag="KB969_000262"
     CDS             complement(52924..53787)
                     /locus_tag="KB969_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6868278.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(53801..54697)
                     /locus_tag="KB969_000263"
     CDS             complement(53801..54697)
                     /locus_tag="KB969_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868279.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(54872..56161)
                     /locus_tag="KB969_000264"
     CDS             complement(54872..56161)
                     /locus_tag="KB969_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6868280.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(56133..57650)
                     /locus_tag="KB969_000265"
     CDS             complement(56133..57650)
                     /locus_tag="KB969_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBB6868281.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            57848..58738
                     /locus_tag="KB969_000266"
     CDS             57848..58738
                     /locus_tag="KB969_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBB6868282.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(58811..59635)
                     /gene="nadE"
                     /locus_tag="KB969_000267"
     CDS             complement(58811..59635)
                     /gene="nadE"
                     /locus_tag="KB969_000267"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBB6868283.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(59647..61119)
                     /locus_tag="KB969_000268"
     CDS             complement(59647..61119)
                     /locus_tag="KB969_000268"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBB6868284.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(61756..62118)
                     /locus_tag="KB969_000269"
     CDS             complement(61756..62118)
                     /locus_tag="KB969_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6868285.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            62341..63093
                     /locus_tag="KB969_000270"
     CDS             62341..63093
                     /locus_tag="KB969_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6868286.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(63233..64156)
                     /locus_tag="KB969_000271"
     CDS             complement(63233..64156)
                     /locus_tag="KB969_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6868287.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(64171..64443)
                     /locus_tag="KB969_000272"
     CDS             complement(64171..64443)
                     /locus_tag="KB969_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868288.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        18614 a        13299 c        11271 g        21430 t
ORIGIN      
        1 aggagttatt atcatgaata acattttagg aaaaaaaata gaacttaaaa aagggatatt
       61 gggcactatt gtcgttgtac tcggtttgtt agggttgcta tttgcgccat ccattattag
      121 cattttttct ttaactatca ctggatttat agcatttaca cttgtttttg gtaaaaaaga
      181 tacgaaaaaa atgttctcga aacctgtcgc tcctgtcaaa aatatagcca aatatttttt
      241 tatcaatgta gtaatcagtg ccgcagtctc ggtatttttg caacaaattt tgaaatgggg
      301 tttaacaggc aatccaataa atgaggcttt cagcccgtta ttatttatta ttttgcctat
      361 catgatactt ggagaagaat tgttctcagt gtattttctc gctatttttt ctagtaagtt
      421 cagcattcct gtcgctagtt tcttgtcagc aatcatcttt ggatttatcc attacagtac
      481 ttatgataat ggaaatattt tacacactgt agcacacatc cttttgatac aaggggtggc
      541 aagattgtta ttcaaccaag ctgccattaa aagcaactcg atcattacaa gttgggcagt
      601 tcatgtgata tttgatttca cagctatatt gctagtcgtt ttattctcct aaatttttat
      661 agaaataata catgctctat tgctaagaaa gcatacttta tttcctttaa acaaaaagac
      721 agatgtatca atggattaaa aatccttgat atatctgtct tctcttttaa tgccagctat
      781 agggatcgaa cctacgacct acgcgttacg agtgcgttgc tctaccaact gagctaagct
      841 ggccttatcc aaaagaaatt atatactcta tttggctgat tgtaaagagt ccgatggaaa
      901 attagtttaa tttcatgata tttttcataa aacgtggtat aattgatgtg aaaggcaggt
      961 tttatgaaaa tggcaacttt tggaaaattt gatacaacta tcgtaccatc ggaaattggt
     1021 gaaaaattca agatcaatac tcacgtaatg ttcacaattc acggcaagtc gcaaactgga
     1081 acgatttcaa agcaattgaa aaattccgct gttgttgaga ttgatgaaac tgcagaaaat
     1141 gcgaacttga tgacgcaaag taagggtgta gtaatcgtta actacaaaga actaaaaaag
     1201 atttgaattt gaccatctct gcatttttgg gatggttttt ttatatgcaa acgaaagctg
     1261 tgaaaaagct gttctgcatc aaacgttaaa aatgaccaaa aaaggatgtg acaaaagttg
     1321 tgtcacaccc tttttcgtat ttacttattt tgtaccaaac aaacggtcac ccgcatcccc
     1381 tagtccagga acgatataac catgttcatt caatttttca tctagagaag ctgtatagat
     1441 gtcaatatca ggatgcgctt cttgcaaagc ttttactccc tcaggtgctg ctaccaaaca
     1501 aacaaattta atgttcgacg cgccacgttc tttcaatgca tcgattgcca tgattgctga
     1561 tccgcctgtt gccaacattg gatctactac aaacaactga cgtgcatcaa tgtcttctgg
     1621 aagtttgacg aaatattcat gtggttccaa tgtttcttca tctcgataaa gaccgatatg
     1681 tcccacttta gcagctggaa tcaattccaa gataccgtca accattccaa tacctgcgcg
     1741 caagattgga ataatcgcta cttttttacc agacaacgtt ttttgtgttg tttcagtgat
     1801 cggtgtttcg atcacgatgt cttccaatgg catatcccgt gatacttcat atgccatcaa
     1861 catagcgatt tcatcgacta cttcacgaaa aacctttgtt ccgcagtttt tgtcccgaat
     1921 aatagttagt ttgtgttgaa tcaatggatg atcgatcact tgaaatttgc ccatttttta
     1981 agctctcctt tgttctgtcg tttcttttta attgtaaaac aaaatcaagt gattgactag
     2041 tcaaactcgc catttttcct aagaaaatcc gtttttgaaa agaagttttc ctgcggacaa
     2101 gcaaagctta ttcttttttc ttgatccaag aagtagataa tgccattgct gcacgcgttg
     2161 cctttgtctg atccatagca tttaccatga caaaatcatg gatgattcct tggaagcgta
     2221 cttgtgtaac aggaacccct gcatcacgaa gtttgcgcgc ataagcctca ccttcatctc
     2281 ttaatacatc cgcttctccc gttaaaatca ttgctgaagg aagatcattt agttcattta
     2341 tatttgctct caaaggcgaa gctgtgattt cagcacgctc ttcttcattc gtcgtatatt
     2401 ggtcccaaaa ccacatcatt ccttctcttg tcaaaaaata gttttctccg aattcatgat
     2461 aggaatctgt atcaaaatca gcgtttgtga ctggataata cagcaattgc ttggatattg
     2521 ggaggccctt tcgttctttt gttaagatcg tcatgactgt agccatgtta ccacctactg
     2581 aatctcctgc aacgattaga ttctcgagat ccagattttt tgacttggct aatttattca
     2641 gctgttgcaa cacagcataa ttttgttcaa ttgctgttgg atattttgct tctggtgatc
     2701 gactatattc tggaaagaca acgacggaat tcgtacgaac cgcaagttct ctgatcaatt
     2761 tatcatgggt ttgagcactg ccaaaaaccc agcctgctcc atgaatataa aaaataactg
     2821 gtaatttatc catattccct tctggtcgta cgagacgaat attgagtttt ccccattcgc
     2881 cagtatccac catcaagtct tcaatatcga cggaatattt gttcacaggt gattcttgta
     2941 cttcttctag taaaactctt ccttcttccg gtgctagttc atagatacgc ggatgaggcg
     3001 catttgcatc actgaatgct actgcttcct tttctaacga gatacgatca gtcatgactt
     3061 ttcctccctg agatttagtg tgaagactaa aattacacct catatactag agagcatcac
     3121 cgatattgtc aaagaatccg ttttcccaaa aaataaacag aaaagcccaa cattgaactt
     3181 ttctgtttac taatggaatt taaattttta ttttttatgc aacggaaatt tttcagttaa
     3241 ttcgcgtaca cctgttttga cttcgtctag ttgagcgtta tcatcttttg cttgtaatgc
     3301 tttgacaact agttcagcca cttttacagc atcttcttct ttgaacccgc gagtagtgat
     3361 tgctggcgtg ccgattcgaa taccgcttgt tttgaatgga cttagtgttt caaaaggaat
     3421 cgagttttta tttacagtga tattcacact gtccaaaatg ctctctgctt cttttccatt
     3481 tatacctaac tcgcgaacat cgatcaacat cagatgatta tctgtcgccc ctgaaatgac
     3541 tctggttcca attgcttgat tgaaaacttt gaccattgct tttgcattgg cgatgatttg
     3601 ttcactatat tctttaaatg caggatctaa tgcttctttg aatgctactg ctttacccgc
     3661 aatcacatgc tctagagggc cgccttgaat accaggaaat accgcactat ttattttttt
     3721 tgctaatgct tcatcgtttg tcaaaatcat gccgcctcga gggccacgca atgttttatg
     3781 agtggtagtc gttgtgatat ctgcataagg aactggatta ggatgaagtc ctgctgctac
     3841 taatcctgcg atatgtgcca tatctaccat cagttttgcg cctacttcat ctgcgatttc
     3901 tctgaatttc gcaaagtcga tcgttcgtcc gtaagcactg gcacctgcta cgatcaattt
     3961 tggttgatgt tttctagcta aaatacgtac cacattataa tcaataactt ctgttgtcgg
     4021 atcaacaccg taagcaacaa agtgataggt tttgccactg aagttgactg gtgatccatg
     4081 tgttagatgt ccgcctgcgg aaagatccat tcctaagatc gtgtcccctg gttctaccaa
     4141 agcgagataa gcagccgtgt tggcttgaga gccggagtga ggctggacgt tcgcaaattt
     4201 cgctccgaat aattcttttg cacggtcaat cgctaaattt tcaacgatat cgacaaattc
     4261 acacccacca taatagcgat gccctggata accttctgcg tatttatttg tcaagatact
     4321 tccttgtgca gccatcactg cttcggagac aaagttttca gaggcaatca gctccaaatt
     4381 atgttcttgt ctttcttctt ctttggcgat cgcagcccaa agatcagggt caaacgtttt
     4441 gtaatctacc acaaacaaca gctccttttt attttcctac aattttattt tcctacaatt
     4501 ttatttttcc catcaaaaac aaattgccaa atattcgtat ctcttctatt acgattagtt
     4561 acgcttagtt tttcgttcac tgatagaaga tttacttgat agcattgtat catactaaaa
     4621 gaatgcgaca ataaccaatt gatcattttt caaaataatt ttgtcctgct gcttttttca
     4681 agcgattcat gtaagcattc cccaatccag tttctggata cacttgtaca aaaatcaaat
     4741 ctaatccaag tgttggttca tctaatcctc ttagacctgc aaacaatcct ttagccgccg
     4801 cttctactga gttgtcgtta tacatataaa cagctgcagt atctgtccgc acttgatccg
     4861 caatttcggg gcttgctatg acacctgcac ggatcttctt attttttgcc cattgaactg
     4921 cagttgacca atcgccatct ctgaccatca gaacacgtgt atcgggtgag tagtgtttgt
     4981 atttcatccc aggggctttt ggtgtttcat tttcttttac aagatgctga tcaatagcaa
     5041 caggagattc gatgactgct tcgatttgtt ctttcgttac tgcacctggt cgtaaaatca
     5101 taggcatggc tgttggatca cttaaatcaa gaacagtgga ttctacacca attcgcgtag
     5161 ctccatcatc aataatcccg gtaatttttc cttgtagatc atgatataca tgatctgcag
     5221 tcgttggact tggttttccc gacgtatttg cacttggacc gacaagcgga acaccggaaa
     5281 gttcgattac ttctagtgtt tttttgttat ccggtatacg aaatgcagct gtggataatc
     5341 ctcccgtcac aactgagggc aaagtgtctt ttttgatctt aaatatcaaa gttaatggtc
     5401 caggccagaa gttcttcaca atcttctctg ctgccggatg aaagttgtcc acatactctt
     5461 ttacttgttc aaaagaggcg acatggacga ttaatggatt atcttgcggt ctccctttta
     5521 cagaaaacac tttcttgaca gcgtttggta aaagagcgtt ggcgcccaat ccgtatactg
     5581 tttcggtagg aaaagcaaca agttctcctt ctttcagtgc ttcggctgcc tcttgcaatt
     5641 ctgtttcatc atatcgtttc gtttccacag tttatccaca accccttttt catacattct
     5701 tattttgtct gagtttatcc tcaagttttc cactgtttgt ggataatcta tttgtcaata
     5761 gtggataaac ttgttgataa accaaaaagt cgtttacatc cttgtcaaat aagtgttttt
     5821 ttataataaa aaaacaaata aaaaattttt catccacaac ttcaaccata aacttggatc
     5881 attcgttcat tgccaaaaag atcctttttt atcgccactt ttttatctgg aaatgcttgc
     5941 tgaaatattt tttttactgc ttcaccttgg cgaaatccga tttctaaaaa aatctttcca
     6001 tttgatttta gtacgcttgg tgcttcaact gctatttttt cataaatagc taatccatcg
     6061 ttctcagcaa aaagggccat tttaggttcg aatgaccgga cactttcatc catcagttcc
     6121 cattcattcc gactgatgta cggcggatta gaaataatca catcaaattg ctgatccatt
     6181 actggtccta atgtatctcc atgataaaaa ctgattttcg ttccttcttt ctgagcattt
     6241 tctttcgcta cttctaatgc ttcttctgaa agatccacag cagatatatg ccaatttttt
     6301 cttgctgctt tcaaactaat agcaattgct ccagtccctg tcccaatatc tatcacttct
     6361 aacggtacac caggcgtctc gtctaaacac cattcgacta actcctctgt ttctggtcga
     6421 gggatcagtg ttgcttcagt tacctttaac cgatgatcat aaaaatctgc atatcctagc
     6481 aaatactgag gtggatgatc tgcaagcaga agtcgcagat cggtttcgat caaccgctgt
     6541 tcttcttctg aaatctcttc gttcatatga aggagccaat caagtttttt ccattgtttt
     6601 cgttccaaaa ataaaaattg gatactatat gcttctttcc catgatcctc taaaaaagaa
     6661 gaagcccgtg acaggacttc tcgataggtc attttaccca ttttgcatag cttccagttt
     6721 tgatgtttga tcatacatga tcaatgcatc aacgatctca tctaatttcc ctgctaaaat
     6781 ctgatctaat ttttggatag ttaatccgat acgatgatca gtcacacgat tttgcgggaa
     6841 attatacgtc cggatccgtt ctgaacgatc cccagttccg actgctgatt ttcgattggc
     6901 atcatactcg ctttgtgctt cttgctggat cttatcgtac acacgagcac gcaagatttt
     6961 cattgctttt tcacggttct tgatttgaga acgttcatct tgcatagcaa caacgatccc
     7021 tgttggtaag tgagtcaaac gtacagcaga tgctgtttta ttgacgtgct gtccgccagc
     7081 acctgaagca tgatagatat ctgtacggat atctttgtct tcaatatcga tctctacttc
     7141 ttcagcttct ggcatcacga caactgttgc ggtggaagta tggatacgcc cttgcgattc
     7201 agttgaagga acacgctgga cgcggtgcgc accactttca tattttaatt tcgaatatac
     7261 gttgtctccg gtgatcatca tgatcacttc tttatatcca ccgattccgg taacgttagc
     7321 ttccatcact tctgttttcc agccttgtgc ttcagcatac ttttggtaca tattgaaaag
     7381 atcgccagcg aataatgctg cttcgtctcc gcctgctgct ccacggattt ccatgatgat
     7441 atttttatcg tcatttggat cttttggtaa aagcaagatc ttgatttttt cttctaagac
     7501 ttctttttct ttttttaatt cagataattc ttcttttgct agttcagcca tttcatcatc
     7561 cagtttttca ccaagcagtt cttctgtatc ggtgattcct tgtactactt ctttataacg
     7621 acgataaact tcgactgttt cgcgcgtgtt tgcttcttct tttgaaagct gcataaaacg
     7681 ctttgtatca gaaatcactt ctgggtcact taaaagttct ccaagctctt cataacggtc
     7741 ttcaattgct tgtaattgat cgtacatgct tattctcctt ctgtaatcat tgatgggtga
     7801 aagtaatgtt ttcgacaaac ggggtaataa gcttcatttc cgccaatttg cacttgatcg
     7861 ccttcataaa cagggtttcc atcaatataa tgtaaattca tgattgcttt tttgtggcag
     7921 aaccaacaga ttgttttcat ttcttcgatt ttgtctgcat aaagcaataa atattttgat
     7981 ccttcaaata actcgtttcg aaaatcattt ttcaaaccaa atgccataac cggaatatcc
     8041 aattcgtcca caattctcgt aaaagcaatg acatgtttct tttttaagaa ttgcgcttca
     8101 tcgatcagca cacaataggg tttgctttcc attttctgaa ttacgtcaaa tacgtctgtt
     8161 tcttcaaata tcggcatcgc attacgtttc agtccgattc ggcttgaaac aacgcctaaa
     8221 ccatctcttg tatcaatacc gcttgtcatt aagacaactg gcttattttg ttcttcataa
     8281 ttatgtgcga cttttaggat ctcgatcgtc ttgccgctat tcattgcgcc atacttaaaa
     8341 aatagttgtg ccatgctctt tttcaccttc cagtttgttc ctatggtatt atacttgatt
     8401 ttcagcattt tttacagtga gaattttcat caagcacaga ttagtattaa atctattgct
     8461 cacttttgtt ccaatttttt gacaagaact aaacatgggt tccattcatc ccataaattt
     8521 ggaaaaactt ccaaccttga aaatcctaat gattcgtaga aacaaatagt ttgatcatat
     8581 atagagtagt gcccctcgtc tacagtcttc acttgcaaat atttgtaatg ttttgctgcg
     8641 taaccttctg cttctttaaa aagttttgtt cctaatcctt ggtgatgata gtcttttttt
     8701 attcccatac aatagaatag atttcggcag tatcttcact tgtctgtgaa agagtgataa
     8761 agcctaaata ttcttctttt cttttttcac accataaagg tagtttactt gattcctcga
     8821 tatatttttc cgttgattca ggaagcccaa accactcagg caagtctagt aatatttctc
     8881 ggacacactt tcctttttcc tctctatctt ttacaaacga tatcggcata ttctttctag
     8941 attctccctt tttgaattga gtatagcatg ctttctttct tttcacgtgc tataataagt
     9001 taaaatttca aagttttacg taaggagcta tttgatgaca aaaaatattt ttgattccat
     9061 cgctaaccat tatgattccc ctgaccgtca agcattagcc aagattattc gcgaagaact
     9121 aactacttat ctaccgcgcg acagccacca aaaagtcctg ctggattacg gaggcggaac
     9181 tgggcttgtt agtttaccgc ttgcggaaag attcaaagaa ctgatcattg ccgatgcttc
     9241 agaaactatg ctgaaaatgg cagaagaaaa gatccaagca gcagatctga aaaatgtccg
     9301 aacgatccac gctgatgctt ctgtcgaatt tcctgctgtc caagctaatc tcatccttct
     9361 atcacttgta cttttacaca ttcctgatac ggagaatatt cttacaaaac tttatgaaat
     9421 tttagctcct ggcggtcaat tgatcatcgt agactttgac aagaatgaac aaattagtca
     9481 tccgaaagtc cataatggct ttagccaaga agaattgaat aatcgattgg aaaaaacggg
     9541 ctttgtctct gctactagtc ataccttcca tcgtggggaa aagctattta tgaacaaaaa
     9601 cgcttcgctt ttcttatcca tcagccaaaa agcttaaaat gagattgcaa aaaaagtgag
     9661 caactccaag aaataagaag gaattttcgg aaaaagaagc tgtgacaaaa aacatgtcac
     9721 agcttctttt tattttttca tcacatgatt ttaatttctg aaagaggcca ataacggaaa
     9781 acaacttttc cttggatcat atctttgtcg actaacccaa acattcggct gtcttttgaa
     9841 atcaagcggt tatcgcctag aacaagatac tttccttttg gcacagtata ttcaaagtca
     9901 ctcgtaaagg tggatgaact ttctgcttgt gcttggaatc ctgagctata agcatattct
     9961 ccttgtaact tatcttctga aaattctttt ttgaactcat ccagataagg ttcatcatac
    10021 tttttgccat taatggtcaa ctggtcattt tccatcttga ctgtatctcc aggcataccg
    10081 atgatccgtt taacaatcat ccgttcttca tcccccggtt cctttgtagt aataatatcc
    10141 attcgttcat agtttgagat cttagatgaa atcaatcgtt gtccatcact taatgtaggg
    10201 tccatcgaat gcccgtttac agtaactggt gtaaacacgt acactctagc taataaaata
    10261 gccgctaata caaggatcaa aatcccccaa tttttcaaaa attctttcac agcttacctc
    10321 ctacttgtat tttcctcgtt atttattacg ttttttcaca atacttcgtt gtactttctt
    10381 tattctacaa tgtttataaa tgaaaggaaa gaataagtga tgtgttcgtc ttatctttct
    10441 cgttatataa aaaaggaacg tgacaaaaga cgtgtcacat cccccttatt ccgaataaac
    10501 gtttttatcg caaccactga tacacggcgt ttcatcacat tatgaatgtc ttcttctttg
    10561 gctacgacta taaaccactg gttcttcctg cgactgtgcc ttttttgcaa tcaatttcag
    10621 acgataaggc tcatgatagc gtaacccgtc tttgacaaaa tcaccgccga cgatgaacaa
    10681 tccgacaggt tccaatgtgt cttctgttga gtcaagtcga atggtcccta ctttttccat
    10741 gtccgagtag cttcgtccaa tatttagaac atactctttc tctcctgttt tcttgacata
    10801 gtaataagga tacaatgtat ttctatcgac cagaaatcca tccatgcgac cgagttcatt
    10861 tgttttgatc tcaccatttc caatcaaata ccgcatattc tcggctaatt tcaattgata
    10921 atcttcgtca taagaaacca tgacctcttg tgtattcact ttatcgatcg aatttccatt
    10981 atctatcgat tcttctgtct ggatgttgaa cgcttcatca ggtaaatact tcacaaaaag
    11041 ctgagtgaca tcggctttcg tgtttttatc taaaaagtaa taaaatacat ttaaaacagt
    11101 aaaataaaca agcactagaa atgcaagtcc atataagaaa aattgaagat agttttggtt
    11161 ttgccaaagt ccataaacaa ttctcaataa ataaagcgtg ggaatcacac ttaaaatcgt
    11221 atatccacgg ttaagatatt taggactgat gtctaaatag ccaaggaatt tatgcacccc
    11281 gttgataagg tctagtaaaa atgtcattga gaatcacctg cttgctggtt atacgtttgg
    11341 gtatttcctg aatcttggtt ttgctgtgct gtacgtgctg catcatcatt ttgcgtgtta
    11401 tcatctacag tcgtactgct tggtatcgtt tcggagctag cacttgtatc cggacttgta
    11461 cttggattgg ttgaatccga tggagtgcca tctggtaccg tattacttgt ttcgcttgag
    11521 ctgtcagttg tatatgtctc atcatacgac gaactagttg ttgtatcgtc ccatgtactt
    11581 gtcgtagtgg tttcattcaa actttccgtt gttgttggtt cagatgtcga gactgaagta
    11641 gttggtgttg tttcttctac agtactagaa cttgaacttg gtgcacggta gctggaacta
    11701 ttcacaatac ctgtagtagt cgcgacaatc gtcgagattg ttaatacagc gattggcttc
    11761 aaaataggtg ctacttttcg catcttatct cttccttcat tgaaatttat tcttgtttcc
    11821 ttactttact acggacaaat tatacagtct accttatttc taccataaat tctttatttt
    11881 tttcttacgt ttttccgaaa gatttcttta attttcctca aaaactacgg ttgatgtttt
    11941 taagtaagct tttgcttccc gattgatttc tttcagatcg catccttgct gcttggcagc
    12001 gaacacgcaa ccacaataac attggcgata aatatcatac tctttgcaca tttgcaaaga
    12061 gcgttcatag cctttgtttt tcttgaaatc acttggcaag tattgtgtcc cgtaaatctt
    12121 ttggatatcc attccgatct gattgatcaa agctgcattt ttctttggcg agatggtcag
    12181 ggcacttcca aagtaatcgt atcctagttc ttgcgctttt tgcgcaacaa gatctaatcg
    12241 catattgaag catgcactgc agcgagcacc accttctttt tcgttttcaa gatggtttgt
    12301 taaaaccatt ttggtgaatt catttggacg gtattcatca acgattagcg caacatgatg
    12361 gtcagttttc tcattaaatt ggtctacaaa tcgtttttgt tcatgtaatc ttcgcaaata
    12421 ctcactttta ggatgaatat tcgaatttga aaaaaataac gtgatctctg catattgaga
    12481 catgaattcc aatgtgtgcg tactgcaagg agcacagcat gtatgtatta atatcttagg
    12541 ctttacttct tctttctccc attgcatgat catttttttc agaactgtat cataatttat
    12601 tttttgattt ttcatttttt ctacgatttg ttgagcatta atcaatttgt tattcctcct
    12661 ccttcttttt tctaggattt tccttattat aagccatttc tattttaatc gaaagctgta
    12721 ttgttatctg tttgataatt tctttgagta ttcctaattc cccttgtata ctggtagaaa
    12781 cgactattgt caggaggata gtactgtgca tgttgattta ttctttcgaa ggctgcagcg
    12841 gcgaggacag aagtttgctg ccaatcattt ctcatcgatc caaatcatcg ttttttatta
    12901 tatattgatg acggtcttat cactcgttct attttatatg ccgatttttc gcgaaccaga
    12961 tagccatgtt tcttttgtgg acatgctgtt catggcaatc agtacagtga gtgtgactgg
    13021 actatcgact tttgatatca attctgtgtt caatgataac ggtattatac tgctggaaat
    13081 attatttcaa gttggtggtt tggggatcat gatgatttct actgcttttg tcattttttc
    13141 taaacgacgg atcacactga aacagcgaca gctgatcatg acggatatga atcaaccgcg
    13201 tttgtctggt atcgtccgac tgattcggat cacttttgct attttaatct ggtttcaatt
    13261 actttttggg acattctttt ctatttattt ttattacaga ggctattttg atcgttggcg
    13321 tgatgccgtt ttttacggtt tttatcaggc gatatcggct gtcacgaact ctgggtttga
    13381 cgtcactggg gattccatca agccctttgc acatgactat tttttcttga tcctgatcat
    13441 gtttttgatt tttgtcggag gaattggttt tcctgtattg atggagtgcc gggaatggct
    13501 attatacaaa cgttccaatg cgaagcttcc gtttcgtttt tccttgttta ccaaattagc
    13561 tgtgttagct tttgttatct tgtttgtttc gggaactgtc ttgatttatc tattggaaaa
    13621 ggaccattta ttccaagatt ccaatatgag tgtcaaatgg atcaattcga tgttttattc
    13681 gattacgact cgtaatgctg gtctgcagat tcacgatttg ggtgattttc aaatcacaac
    13741 actgatcatt ttttctttac tgatgtttat cggatgcagt cctagttctg taggcggcgg
    13801 gattcgaaca actactgtag caatcatcgg tttgtatcta tattccttcc tcaaaagtga
    13861 agataacatc aatatttttg gacggagaat cgatcaagat gatgtgcgaa aatcagtcgt
    13921 tgtctttatg ctttctcttg gtatgtgttt cttttgtatc gtttttttat ctgctacaga
    13981 agaacaaacg ctgatctcga tcatcatcga agtaacttct gcgtttggaa caactggttt
    14041 atctttaggg attaccggag acttgtctgt tgtgggcaaa atcacgattg ctacactgat
    14101 gtttattggg cggatcggaa tgctatatac attgatgtta ttcgtgccaa aagaaacacg
    14161 agatctaggc tatgaatatc caagcgagaa aattattatc ggttaaaatg ggaatatagg
    14221 taagagggaa taataaaatc acagcagctt gaaacaatca ttttgtttca agctgttttt
    14281 ttgttaaatc atgcgatttt gtccgatttc atgcactttc agccgtaacc ttttcttaag
    14341 aataagaaaa gcaatttaac ctttttttca acatatggta tgattagttg aatttattcg
    14401 tcagcaaatc gtttttggag gttacataat gggaatacgc agtcattttg cgattgcagt
    14461 tggaaaaacg tcgcaatggg cattaaaaac tttttttaaa ggcggatcaa gtttaccagg
    14521 taaactagcg ctgaaagtcg atccacatat actagatagt ttggcaaaag actaccaagt
    14581 cgtcgttgtc accggaacaa acggtaaaac attgactacc gctttaacag tcaatatttt
    14641 gcgccagcaa ttcgatgaag ttctaaccaa ccctactggt gcgaatatgg tacagggaat
    14701 tgtatcgact ttcttgcagg caaaaccaaa aaaaggacag aaaaagtttg ctgtcctaga
    14761 aatagatgaa gcaagtttga gcaaagtcac agaatatatg aaaccagaac tgttcttatt
    14821 tacaaatatt ttccgtgatc aaatggatcg gtatggagaa atctatacga cctataaaat
    14881 gattgtagac ggtgccgcaa agtcaccaaa tgcaacgatt atcagtaacg gtgattcacc
    14941 aatcttcaat tctatcgaaa cagtcaatcc tagaaaatat tatggctttg accatgaaga
    15001 agatcgtgaa caaatggctc attacaatac agacggtgtc ttatgtccaa attgtcatca
    15061 catcttgcat tataaaatga tcacttatgc aaacttaggg aaatattact gtccaaattg
    15121 tgacttcaaa cgtcctgaat tggattatcg attaactgat atggtacgga tggacaatgt
    15181 gtcagcagat ttcgtgatcg atggtcatga atacggaatc gaagttggcg gtatgtataa
    15241 tgtctacaat gctttagcag ctactgcagt ggcagagtac ttcaatgtcg atcctgataa
    15301 aatcaaacaa ggtttaggat atgacgagaa agtattcggc cgacaagaag tcatcaatat
    15361 caatgggaaa aaatgtacat tagtacttgt caaaaatcct gtaggtatca atcaagtaat
    15421 cgatatgatt ggtctagctc cttatccatt ttctttagtg gctttattaa atgccaatta
    15481 cgcagacgga atcgatgtca gctggatttg ggatggtaat tttgaaaact ttgccgatat
    15541 ggatatccca gctgttattt ctggaggaga ccgtcataca gatatgactt tacgtctaaa
    15601 agttgccggg attccagaaa ataaattgac agaaacaaaa gaattaccag aagtaatcga
    15661 aaaaatcaaa gaattgccaa ctgagcatgt ctatatttta gctacttaca ctgctgtatt
    15721 gcagcttcgt aaagaactag ctgctcaagg atttatcaaa ggaggaatga accgtggcta
    15781 attatgaact caatatcgcc cacctttatg gaaatttgat gaacacatat ggtgataacg
    15841 gaaacctttt gatgttgaaa tatatagcag aaaaaatggg ggtttcttgc catacggaga
    15901 tcgttagtat acatgaacct tttgatgctg ataaatatga cttggttttc tttggcggtg
    15961 gtcaagactt tgagcaatta atcatttcaa aagacatcca gaaaaagaaa gattctttga
    16021 tcaactatat cgaaaatgat ggcgtcatgt tagccatttg tggtggctac caattgctag
    16081 gtcactacta catgggagct aatggagaaa agatccaagg aatcagtgca ctggatcact
    16141 acacgttaag tcaggaaaat aaccggttta tcggtgatat cgttatccat aacgaagaat
    16201 tcaatgaaac ttattatgga tttgaaaacc acaatggtcg gactttctta ggtgaaggtg
    16261 aacgaccttt ggggaaagtg gtacaaggtc aaggaaataa tggtgaagac caatctgaag
    16321 gtgtcattta ccgaaatgtc ttcggttctt atttccatgg acctatcctt gcaagaaatg
    16381 agaacctggc agctcgtttg atccgcctag ctttagaaca acgttacggt aaagaattgg
    16441 atctgcccta tcttgaagga caaacagcct agttattcga aaaaggggaa tgtgacaaaa
    16501 atttcgtcac attccccttt ttcgtatcct attttaagcg acttgcttgg cataacggtt
    16561 cacgttttgc ttgatattcc cgattgtttt cggatcattg attcctgtga cttcttgaat
    16621 caattgttcc aagttttcat ggatcttcat ttcatgcaat tgacggcttt gttcatcttc
    16681 aggatcatag taattaaaaa taatccccat tgttgccgtc aaatgtgggc aagtcaagtt
    16741 atgttcttgt agttctctca ctggacgtgt aaatctttct tgataaccta acttacgtaa
    16801 tggtgtccga gcgacacgtg tgatcgcatc agagatattt ttgttttgga agcgatgaat
    16861 gattttttca atatacgcat gatgctgctc tgcatcaaac ccccatttgg caatcagcaa
    16921 acttcctgtt tcctgcaaaa ctgattttaa ttgtgccaca actaacgcat cttgcattgc
    16981 ttcatcaatg gtctggtaac ctaacaaggc acctgtataa gcgacagtcg catgaccagt
    17041 attgacacta aatagtttgc gttcgatata tggttctaga tcatctacat ataaaacccc
    17101 ttttaattgg atttttttat tttttctttg gctatcgtca atgacccatt ctttgaaagg
    17161 ttccacttgg acgaataaag gatcttcatg gtgttgtaat gggacgattc gatcgactgc
    17221 tgcatttgga aagccgatat atttgtcagt aaatgatgtt tccggaagat atttatacac
    17281 ttctttttct agaaatgctg aaccgccaat catattttca caggcaatga tatctaaaga
    17341 tgttgtgctt ccttcctttt ctctttcttg gatacctttt gcaatcaact cagcaataaa
    17401 aggtaagata ttcgggccaa tggcggtagt aactaaatct gcttcagcga tttcttggat
    17461 tactttttct ggatttgttt gattgttgat tcctttgaca ttttttacag tgattttttc
    17521 ttttgattca tctgctaatt cgatttcgta ttcttttctt tcatttaaag catcaatgat
    17581 cgtgtgattc acatctacga aagtaatctc aaatccatta gctgccaaaa cctctccaat
    17641 aaatcctcga ccgatatttc ctgcaccaaa atgtactgct ctcatttttc tctctcctta
    17701 agcaattgct agattttccg ttacttcttc tttgctgagc gcgtctgcta gctggacaac
    17761 attgtccata tcactgcaat aaagtgcgat ttgctgtaca agttgcaaat gctcatctcc
    17821 gactcctgca ataccgaaca aaacagtcgc aatcttttct tcttcttcgg taccaaaatc
    17881 tacaccatct ggtacttgaa cgacacagat gccggatttt ttcacatatt tttttgcttc
    17941 atctgttcca tgaggaatcg cgataaaatt ccccatataa acagataaca ttttgtctct
    18001 atctaccatg gcatcgatat attcctcatc aacgcaccct gcttctacaa gcatctgacc
    18061 gcaatagcgg atcgcttctt ctttggtttt aaaagatcga ttgagctcga tcatgtcgaa
    18121 tggcaaactt tgcatgctgt tttcctccct taagctgtct gtttcaaata ttgtgcaatc
    18181 gattcgtatt tttgcggatt gaccatgctg ttgactgata aatgaatgga ttgaggtgca
    18241 gccatctgta ctttttccgc taaactttct ttggctacga tcagtgaatc aggttcatct
    18301 tttaaatctt ggatattgac ttttcttaac gggatagtta aatggttctt gtctaatata
    18361 tctttgagca cggtcatccc cattgttgct gatccggaac gatcatcgtg gacaagtaga
    18421 atctctttga tttgtttgat gtttgctgaa agaaactctt ctgctggctc attctcaatt
    18481 tcagaaactg atgttttctg cttgctgctt aattcttgaa tgatttcatc atatcgaggt
    18541 gaattcaaaa agttttctac tgagacaaaa cgcgcgctcg gtgctttttg ttttgctctt
    18601 tcttgtagtt cgacctgagt aacgatcaat gtattcgagt catctgtcag ttggctgatt
    18661 gcttgattgg tcaccgtttg aggcaagtct gcttcctgta ctttttttct caagatcgaa
    18721 gcgcccatcg cacttgatcc cattcctgca tcacaagcaa aaatgatttt ttgtacgcca
    18781 gagaatgtag ctccttgagg aataccttgg gcacctttgg aagcttgctt agctgccttt
    18841 gtctcttgaa cagatttttc gaagtcttca tttgtatctt tcgcatccgc tttcaaaatt
    18901 actgcagaaa taccaaacga aacagctgcg gcaacaatca cgcccaaaat aacaggaagg
    18961 taagaattga acggtgtcat cgctagaatc gcaatgatcg accctggaga agctggcgct
    19021 cttagtccag catccatcaa ttggaaaatg aaacttcctg acattcctcc gcctataact
    19081 gataagaata ataacggttt catcataacg taaggaaaat agatttcatg gatcccgcct
    19141 aaaaagtgaa tgatcatggc tcctggtgct gaagattttg ctgctccttt gccaaacaaa
    19201 gtaaaagcaa gtaatacgcc aagtcctgga ccaggatttg cttcaagcaa gaatagaata
    19261 gattttccag cctctgctac ttgttcagtt cccaatggtg tcaaaatccc atgattgatt
    19321 gcattattca aaaataagat ttttgctggt tcaataaaaa tacttgtcaa tggaatcaaa
    19381 tgggcagata aaatgatctc tacacctttt gccattgctt gagtcaatgc atcgacaact
    19441 ggaccaatcg cagaaaaacc taataacgct aatccaaaac cgataagacc tgctgaaaaa
    19501 ttattgacta gcatttcaaa accggatttg atccgttttt ggaatagctg atcaaatttc
    19561 ttgatggcat atccaccaag aggtcccatg atcatcgcgc ctagcatcat tggaatatct
    19621 gttccgacaa tcacacccat cgttgcaatt gccccaacaa ctgatccgcg gtcaccagca
    19681 attacttttc cgccagtata accgatcaat aaaggaatca gataagttag cattgggctt
    19741 accatggtag cgaaagcctc atttggtaaa taaccatctg ggataaatag agccgttaat
    19801 acaccccagg caatcagtgc tccaatattt ggcatgacca tgcttgataa agtactgcct
    19861 aatttttgta ccctcgcttt tagcgaaatg ttgtttttgg gaatcgtccg ttccattttg
    19921 tctctccctc tctccttttg atactctaat tgtatccgct tactaaaaag agaaatagtc
    19981 gtactttggc acgaaacttt gtgccaaagg tttgagtatg tcagcaaaat aaaaagattt
    20041 cggtatcaga aaacttcaat tttaaataaa actgttattt taattttttt ataatatgca
    20101 aacaataact tttgttagca tttaatttag atgttttcca ttctattatg ttattaaatt
    20161 ttatattgga ggcctatcta tgacattact gatcaaaaac atgaacatga aacgtggtaa
    20221 aaaacgtgtg attcgacaat tgaatctttt agtagaatca ggagaagtag ctgctttgat
    20281 tgccccgaac ggatttggca aaacaacttt gctgaatggc attgcccaac tgctgccaac
    20341 aacttatgat caattgtccc ttcacaacat ctctcctact gcttatacag attatcgccg
    20401 gtctttcttt tttctagaat caacgaatca gttatccgac tatctatcgg ctgttgatta
    20461 tttgactttg atcaaatact attggcagag caaagtagaa tgccaaactg ttttccaacg
    20521 attgaagatg actgagtacc ttactttgcc gattggaaaa atgtctctag gaatgaaaca
    20581 acatgtcttg cttgctgctt acttgatcag tgattcatct gtcatgttat tcgatgaacc
    20641 gttgaacgga ttagacccag gaagtattga tatcttgaat agcctcatca gacaatggca
    20701 gaaagagggg aagacgattc ttctttcttc ccacgctatc gcgaatatcc aatcgatttg
    20761 ttctaaagca tgttttctaa aaaatggaga aatcgtcaca gaatcctcaa atatggaaga
    20821 gattttagct atttatcgta aattatatga ggtgtaacta tgtctttact tacatttgaa
    20881 cgcaatctct tactaaaaaa caaagtaaac tttttatttc ctctattgtt ggtcgtgctc
    20941 tttgcattcc cacttttttt tgatcataaa cttgcttata cagaattcga tgaactgaat
    21001 cataactatg aagagatgca acgtttgatt gaaacgttga aagaagatga gaatgagaaa
    21061 gaatttgtgg aaagtttaga gaaaagcaac aaactgatcg aagcaatctt acatgcaaaa
    21121 aacacaggga atgtccagca aatggtcgaa gcaacttatc attatgaaaa agatatactg
    21181 gatcgactga tttctggtca aagacaagga attccaatca ttgaacaaca aaaacgtgtc
    21241 gagttgctcc gttatatgaa agaacatcag atccaaagat attctatttt tgacttgcca
    21301 gcgcatctct ctttagcaaa ttactacgaa aatatttttt caggaatgat ttctagtttt
    21361 ttgattttat gtataaccgc cttgtttctt tcttccatca tctcttatga aaaaagaaag
    21421 caggtaatct ctctagtcaa tctattactg gatagtatgg taaagaaaca tagcatccgt
    21481 tttaccattt attatggtgc agctatgcta agtctcgtga tgccattttt gatcgtctct
    21541 atactagtaa taatcaaaaa tggtttggga gacttccgtt atcctgtagg aacgatcatt
    21601 ggtcaggaga tacgaatcct gccgatgtat gagtatcttt tccagagctt tctgttcctg
    21661 ttgttgtggg tgctcttttt aagtacaatc agttttcttc tatctgcttt atttgaacat
    21721 tctctagtca atcttttagg tacacttctt tgtcttttct tagcagagta tcgcttgttt
    21781 tcttcgattg gatggataga atcaatcagt cattacttgc caacttctta tgttgatttt
    21841 caaaatgtga tcataggagg agatattttc tcgccactag cttcagaaca ggttactttc
    21901 atgaatggta tcttgacact tggtatatgg agtatcgttt tattattcat aggtatgggc
    21961 actatctata taaaaaagag ctattaaaac acaaaaataa taggggcggt gacaaaaacc
    22021 ttgtcaccgt cccctatttc aaataaacgg ttttctagaa taaatagttt tcaaaagctt
    22081 gcatccgcag taataagaac ctcccaacaa aaatagctcc tcttattttt atcttggttg
    22141 aagttattac ttgatgcaag gcagcttttt ttactgtgaa cattggttat atatgtccat
    22201 gttcaaaaat catttggact tcttcaatgg tttccgcatc actgagcgcc attacttggt
    22261 cgatgtctga acagaaaaag gctaaatctt ggagcaccgc taactgatgt tcttttttta
    22321 aagccactac aaataagagt gtcgcgattt ttggttcctc ttttgttcca aagtccacac
    22381 catcaggcac ttggactaaa tagattcctt cttctactac ttcttcatct ttgtcagtcc
    22441 catgtggcaa ggctacgaaa ttcccgatat agacactcgc tttttcttgt ctttcgatca
    22501 ttgattggat atatgccggt ttgattcccc cttgttgggt catccactgg ccgatctcgg
    22561 tcaacgcttc tttccaattt tgataggatt gatcgagcaa tattttttct gctggtagct
    22621 gtatcatctt ttcaccttca tttctttatt tcttcaatca ggattttcgc taacaactga
    22681 taaacgattt ctttatttcc tgagcggaag atctcggtgt tcaagtcatt catgatgatt
    22741 gctccactga tctttcctaa aagaatcccg tctttttctt ggattggcga aggcgccagc
    22801 ataactaaca tacgggacaa atcgactggc tgtctatcca tcccttcaat ggtcaacgga
    22861 tgtttcaaat tgaaaataca aaagatcggt ttagaaatca atgagctgga tgtatggaat
    22921 aaccccatat ttgtatgagg aataccgata ggtgcttgtt catatcgctt aagcagccgg
    22981 cgatgaacca cctcttcatc cgttactagt ccttcaggaa aataaggaaa taagctgcga
    23041 atcgtttcgg aaatcgtctc aggattatcc agttcttgga taaaaaaacg accgagtaat
    23101 tgattgattt gatccatgaa atgcattgtt tcctcataag tatcttctat catccactcg
    23161 ttattgctgt tatacgtaat tttttgcctt tttttcttct caatatgcga aaaagcttct
    23221 tttagctgct tgacttcatc ttctagcagt agcggggaga ctaaaatata ttttccaccg
    23281 tatcctggta aaatagatgt agaaataaca acatcatatt cttcttgtaa atcgattttt
    23341 tttaaatcag caatccgata gaaatgaatt tgttggatga agggaaaata ccttttcaat
    23401 cgtagttcca acatgctagt agaagctaat ccacttggcg aaaatcctgc aatactgata
    23461 ttgctttctt tcggacttcg ttccaatgaa ttcgcaaaat gaaggaccat ataagcgatc
    23521 tcttcttcgg ataatttttt ttcttgaaaa atccgctcta ctgctttacg gattgcattc
    23581 gcaacttcct cgtattgaac catgattttt tctaaaatcg gattggtcag tgtctcttct
    23641 tgtaaaacgg ctcttgaaaa cacaccagat aaatgagtca acagcatttt gtacaaagtt
    23701 tcatcttcat aaaaatggac attcgtctct tcacttactt cttgaatcag ttgttttact
    23761 aaataagcaa gctgtgtatc gaacgtctct tcaaagaaat tctgatcaaa tgagttcgtg
    23821 aagtcattta ataatcctgc aaaaaagacg atctcattta ctggataaag ttgttttgtc
    23881 tcagaagcga tccgtgaaaa caatcgttta gctgtctgta gtaattcttt gtttgccaga
    23941 ctattatatg tctcatttgt cagtaaatga tttttcgtca cacgctccat cgtcaatgtc
    24001 agcatcaaaa ccaaatgttc aagctttcta tcacttagat tggtcttttt ttggatcaat
    24061 tcttccccga ttactttgcg tgcaagagat agatgttgcg gatcaacgaa tcgaaaaaaa
    24121 taattcagtg atgcatcgaa agaaatacta tgaaaaagtt catattcatt gatttctaat
    24181 tctaatacat tcgctgtcag aagccggcgg tatttttccg gtccttcgat ctcgtatccc
    24241 tggttccgaa tgatttccaa aggcagttgg cgaatacttt cttccaactg tttgatatct
    24301 gcataaaaag tggtattact gatgcgatat gattccatga aatgagcaag actcaacggc
    24361 tctgtcgtca gtaacaactc ggctaaaatc gcgtgttgtc gtttagcagt ggataagtca
    24421 ttacttttcc catctgtatt ttcttttaat tgctctaata cttcttctga tgcctcaatg
    24481 acaaatgagc ctctagctgc ttttttcaaa gaagcattta ccgatttcaa tgagacttca
    24541 agattatcta attcgcggta aatagtccgt ttactgacct tcaataaatt catcattttt
    24601 tggatagata caggtgacgg gctactgaga aattctgcta ataattgttt ttctctgggc
    24661 gataaataca tcttatattt ctcccttcac gagtttttcg tattcattcg tagctaccca
    24721 atgttcaact agaactagcc gagggatctt ttcttctagc tgttcagtta cagctagttc
    24781 tctttgtgcg atataaatcg tttcttcttg gattttgatt ttttctattg attcttttga
    24841 gataacaaac tgttttttcg ctttttttgc taattgactt aaaatcgtca tgcccatagt
    24901 ttgtgagccg cgtctgttgt ttttatacaa aaatacaata ttagcaggcg acgttttttg
    24961 ttctgtgata tctgctatct cttttttttc ttcccgcttt ggaaattgga tcgcttcttt
    25021 tattcgtgac agcaagatat ctgtttccaa aaagtgatcc agtacataga tttgactttg
    25081 aggtactttt tctcttgcaa gacccgctag ttcatgttgc acgataacca gctgatttac
    25141 ttggttattc aattcataga tagagctgta tccgacagaa agatcgattt tttctgctgc
    25201 taatttcttt ttcagcaggg cggctcccat agcacttgat cccatacctg agtcgcaagc
    25261 aaaaatgacg gaatgaatga tagatggttc caagatttct cccctttctt tgaccgtttt
    25321 gttctctttt tctttatttg gtaatttcaa tagtatcgct gcacaaatga aggtcacaaa
    25381 tgtactgatt gctatcccta tacttacccc agctagttgt ggataaggcg cattggcaaa
    25441 aatcacgagt agtgacccag gcgatacagg tgcagctaat cccgtatcta accattgaaa
    25501 tatcaacgtg ccgcttgccc caccagccat tacagctaaa aatagatacg gtcgcagcaa
    25561 gacaaatgga aaatagattt cgtgaatccc gccaatcgca tggatcatca atgctccact
    25621 cgcatttact ttttcctgtt tttctgcaaa acaaaggata gaaagtaaga tccctaaacc
    25681 aggtccagga tttgcctcca tcaaaaataa ggaagagtac ccgactgttt gtgagaattc
    25741 gattcctaaa ggtgtcaata caccatgatt gattgcatta ttgaaaaata gtacttttag
    25801 aggttctaag atcagactga caagtggtaa cagattcatt gtgactagcc aagacacaac
    25861 ggaggcgagc aacaagtgaa cactatttaa aactggttca ataaaaacga ttccaattat
    25921 acaaataacg ctaccagtca gtcctactag taggttgctg acaagcattt catatccagc
    25981 cttgaatttc acatggaatc tagaaacaaa ttgttcatat acgatgccgg caagcggccc
    26041 gataatcatc gctcctacga tttgtggagc attggaacga gcgatcaacc ctaaagaagc
    26101 aattgcaccg gcgactgccc ctttttgtcc ccctaccgat ttcccgcctg aataactgat
    26161 caagatgggt aaaagcagct ggatcatcca atggcatacc tcttctaatg tggtgtgcaa
    26221 atcgccagac acaccttttg ttgctaatga caagattccc caagcgataa acagacttag
    26281 atttggcatg atcatttcat ttaagtgatg tccagctttt ctcagttgtt tcatagacac
    26341 gcgactgctg ttgtttgctt tccatttgta ttccatcttt ttcaccagac ttctatttat
    26401 tgatggacgg attttatgta gaaaaagcag caaacgaaaa accgtctgct gctttcagct
    26461 atctgggaac tatttgcctg gttcagacgc aatgattgct agttcacctt ggaccgccca
    26521 ctcagaaacg ccatttggaa taatacagct tgttcctttt tctaatggat atgtttttcc
    26581 gtcaacgaca aggtctcctg ctccttcgat taccgtcatc aatgtataag gggcttgttt
    26641 tttgaaagat gtgattcctt taatatccca ctcatataca ttgaaaaact cagtttctaa
    26701 ataagtgacg atcgatgaat tcccttttcg gacttctttg atttgtaatt ctggtgtttt
    26761 cgcagggaca gttgttacat cgatcgattg ttggatatgc agctctcttg tttgtccttg
    26821 cgcatctttt ctgtcgtagt catacacgcg gtaagtcgtg tcagaacttt gctgtgtttc
    26881 taaaatcatg attcctttac caatagcatg gatcgttccg cttggtacat aaaagaaatc
    26941 acctttttta actggtactt tcttcaaaag gtcatcccag cgcccatctt tgatcatctc
    27001 agctagttct tctcttgtct ttgcatgatg accatagatg atttctgcac caggttcagc
    27061 atcgatgata taccagcatt cagtttttcc taattcacct tcatgtttca tcccataggc
    27121 atcatctgga tgtacttgta cagatagatc atcttctgcg tctaagatct tgatcaataa
    27181 tggaaacact ggttctgaag gatggccaaa caattccttg tgttctgacc atagttcatc
    27241 taatcttttc cctttgaatt cgccattttc tactacactg acaccatgag gatgcgcact
    27301 gatcgcccaa tcttctccga ttttatcgtt agggatatca aaaccaaaga ctgaacgtaa
    27361 acgacttcct ccccaaattt tttcttgaaa aactggtttt aaaaacatag gttcctgcat
    27421 aattcaaact cctctcattt ttcatagcta ttatagcatt atttcggtaa taccgctttc
    27481 tctttcaaaa agttttcaac aatttcatct cgacatatga gatactccgc acgatgatcg
    27541 acaggatgta cgcgatttga caaaaatatc aacgcttctt gtgtttttat atcaatcaag
    27601 aaaaacgtac ctgtataacc agtatgaaaa agaatcgcat gaccgtcttc tacatccttt
    27661 tttaagtccc atcctaaaga acgatagcca ttttttttcg gtgtttgatc ttgcagtaaa
    27721 gaatcaatcg tctcttcttc taaaaaacga ccattacgga tttttccctt gttcaaatac
    27781 atttggacaa aagtaatgct gtctttcaaa tcaataaaga gacccgcgtt acctgcatgt
    27841 tcagccaaaa ctcttgcttt cggatcatga gtttgtccac gcaaaacctc acccgaaggc
    27901 agttgttctg tgggaacgat ttttttggaa ggaaaaggaa gaaataagct gttcatcatt
    27961 cctaatggtt ccaatacttg ttcttgaaag atttccactg cagtttcttg gtaaatttcc
    28021 tctagcatca acccaagaag aatcgtaccg gcatctgtat attttacttc ttttcctagt
    28081 tgctcacctg gttctagctt caaataagcg gcgatcaatt cttcctgaga tagcttatct
    28141 ctgtttggta tccatgtttt gatatcagaa gtatgtgtca gtaaatgacg caaagtgatt
    28201 gtctgatttt caaattcagg aagatattta tgaagcggtt gatcgagttc tatctttcca
    28261 tcttctaata gacgtaaaac taatgaagtg gttgcaacga ctttcgtcag tgaggctgca
    28321 tcaaacaaca gatcttctgt catcagctgc ttttcaggaa cgacttgggc aaagccggct
    28381 gtaaatgttt ctacttgatt ttcttttatg aaggcgactg ctacacctgg ataaaatcct
    28441 tcttccatct ttttcaaaat aagctgtttc gtgtgtggat acatcttttt ctcctgcttt
    28501 tctatcagat tcttacagtc caagcttaaa gcttaatcta tgaggaatca acctttttta
    28561 cacaaaaaaa ctgcgcgaaa aaccgcgcag tttcccccgg tatactattt tctctttcta
    28621 tctctagaat aagcgatagt atgaccgttc ataaaatgac gagacatgcg acaatcgtta
    28681 agaaagaaaa agttaagcgt cgcatcgaat gtcagtttta ttcttttctt ttggctcact
    28741 gacgaaccac cattcgattc ctatagcatc atagattgtg agtactgtgt gctttttgtc
    28801 taagaagaaa tcaactgata gttgctgcaa gtgagcaatc agtccttcca tgctttcagt
    28861 atcgatcatg aatttcagaa aatcaagtcc aatcacttca tctgtaggca aatcaattgc
    28921 gcctccgcta gcttctgtca aaccaacatg gaaatctcct tcattcaata catggatgcc
    28981 ctcttcttca ttatgtacct tcaaaccaag tacatgatta agaaattggc gttcttttgt
    29041 taagttagta acatttaaat ggattttttc aaaataagaa cctgttgata gtttactgaa
    29101 tttttcttca gattttctta ataatgcttc ttgatccatt gtttctggaa tttctctttg
    29161 gtcgttctta ttctcttcat ggtaaatttc caattcattc tcttctgggt ctacgagcaa
    29221 aatccccata cgtccatgat cttctaaagc ttctttgatt ggataattca ttttacggat
    29281 acgacaaagg atatctgcca tttcttctgt gctagggata atcaatgaaa aacggttcag
    29341 ctttttgatc acccccatgt gatcattcgc tctaggactt tcttccagca gcaacatttc
    29401 acttccagct tcttctgttc ctaaaatggc taattcgttt tcttctcttt tcaaatcaaa
    29461 gccaacaacg ttcttgtaaa aatcaatcat tttatctcgg tctttcaccc gaatggctac
    29521 actttttaaa taggtggcag cccccaattg aaaatctttc atatttcttg ctcccctcta
    29581 cgtcaagctt tattttaacg atggattctt cttctttcaa gcaataactt tgattttgtt
    29641 aaaaaaaatg tgagaaaatt cgcattttgc ttgttttttg taaattaatg agtaaaaact
    29701 cttataaaaa gaggttgtga aaaagctgtt ctgcatcaag taataagaac agccaaacaa
    29761 aaatagctcc tcctattttt cgtttggttg ggcttattac cgcagatgca agcttttgaa
    29821 caccgtttaa ggaagaggtt gtgaaaaagt cgcttagttt cgagtagtaa gaaaaatttt
    29881 gtgaaaatgg ctttctacat ttttgcataa atttggctta ataccgagaa actggctttt
    29941 gaacaccgtt taccaagagg ttgtgagcct gccgtttaac tccgagtcac aaggagcaat
    30001 ttcaaaaaac agcttctcag gtttgttgac tattgtgact tgtgaccgag gagttggcag
    30061 gagaacaccg tttaaggaag aggttgtaaa atcagcggtt tgacctgagt attagagata
    30121 caaaacggaa aaatagcttc tcatattttg ccgttttttg agctaatacc gaaggacagc
    30181 tgattgaaca ccgtttattc ggaaaaaggg actgtgacac gacttttgtc acagccccta
    30241 aaaaaaataa taaatttgta ctattctatg aagcttcttc ttcagaaaac tgactgttat
    30301 aaagatctgc atagaatccg tctttttcca tcaatgtatc gtggtttcct gtttctacga
    30361 tcgaaccatg attcatcaca ataatgttgt ctgcatcgcg tattgtagac aagcggtgag
    30421 caacaacgaa acttgtccgg ttttccaata ggcggttcat cgctttttga atcagtattt
    30481 ctgttcgtgt atctacacta gatgttgctt catcaaggat caggacatct ggatttgcta
    30541 agaatgcccg cgcaattgtg attagctgac gctgcccttg cgaaatattg cttgcatcct
    30601 cgtttaatac agtgttatat ccttctggca atttacgaac aaaatcgtct acgtgagcag
    30661 ctttagcagc ctcaatgatt tgttcgtctg ttgcatcgtc gttcccatat ttgatattgt
    30721 catagatact tcctgtaaac agccaagtat cttgcagtac cattgaaaac tgtgcgcgca
    30781 attcatcacg tgaaagatca cgggtatcta caccatcgta acgaatacta cctccagaaa
    30841 catcgtagaa ccgttcaaga aggttgatca gtgtcgtctt ccctgcacca gtcggaccta
    30901 caatagcgac catctcacca ggtttgacat ccaagttaaa atcagtcatt agcaagttat
    30961 ctggtgtgta gccgaattga acattttcaa aacgaacttt gtatggtgta tctttttctt
    31021 ctggaaggcc agatttttca ttggacatct cttcttcatc caacacttca aatacccgtt
    31081 cggctgaagc aactgttgat tggatagtgt tcatcaaact tgcaagttga gtgattggtt
    31141 gagagaactg tgttgtatat tgcaagaacg cttgaacatc ccctaatgtc atgttcccat
    31201 ttgcaacttt tactccgcct agtacagcga cgaacacata gcctagattt ttaacgaaat
    31261 tcatcaacgg catgatgatt gccgaaataa attgagcttt ccaaccagcg gcatacagat
    31321 tctgattttc tttttcaaat acttcctggt ctttttcagt atgattgaat gttttaacaa
    31381 tggtatgacc accatatgtt tcttctactt ggttattcaa taaacctaaa cttttttgct
    31441 gatctgcgaa aaacacttgt gatttcggcg ctacgatcat cacgatgatc aagcttaaag
    31501 ggatcatcaa taacgcgact aacgtcaatt gccagctgat tgaaagcatc atcacgatga
    31561 ccccaatcaa tgtgactgca ctagttacaa attgagtcaa attttgctgc agcgtgcttg
    31621 cgatgttatc catatcattg attgctcgag acatgatatc cccatttgta tgtgtatcat
    31681 aataggaaat cggtacacga ttcattttgg cttccaaatc atgacgtaat tcataaactg
    31741 ttcgttggga aacacgtgtc ataataaatt gctgtaaaaa gttgaataca gcagaaatca
    31801 aatacatcac gattactgtc gcaatgatct gcgcgatttt atcaaagtct atcggaaatt
    31861 ttgttacttg ttggccttgt tgcatctgtt gagcgccagc cattacacct ttgaatattt
    31921 ctgtggttgc tttccccaag acctttggtg tttggatttg gaagatcacg gctgctattg
    31981 ctagtacaaa tacagcgatg atcgcaacca tacgtttaga catatagcca aacaatcggc
    32041 gtaccgttcc ccagaaattt ttaggctttt caccttttac accgagattt ctgccaggtc
    32101 caccatgtcc tggaccgcct gctggtccat gagagggacg tgtgtttgtt ttactcatgc
    32161 taagtcctcc tctcttagtt gtgaatgaac gatttcttga taagtttcgt ttgttgctaa
    32221 tagttcttca tgtgttcctt tgccaaccag ttttccttca tctagcacaa ggatcatatc
    32281 tgcatccatt actgtactta ctcgttgagc aactaaaacg gtgatacttt ctttcatatt
    32341 cgttttcaat gcttggcgaa gattggcatc cgttttgaaa tccaacgctg agaaggaatc
    32401 atcaaacaca tagatatctg ctgttttgac taatgcccgt gcaattgcca gacgctgtct
    32461 ttgtccacca gagaagtttc ctcctccttg ttccacatgg ctatctaagc catcttccat
    32521 ctctgaaaca aaatctttag cttgtgcgat ttctaatgct ttccaaatca tttcatctgt
    32581 tgcatccggc ttaccatact gcatattgtc tcggatcgtt ccagagaaca gaactgcttt
    32641 ttgaggaaca aagcccatta attctcgcaa attatattga gtcatgtcac taatgtccgt
    32701 tccatttatt tggatcgaac cagattcgat gtcatataat cgagggatca aattgactaa
    32761 ggtcgtttta cctgaaccag tcccccctat gattgcgacg atctcgcccg acttggcttg
    32821 gaaatcaata tcttccaatg caagtttttc tgctccatga tatcgataat tgacatgatt
    32881 gaaggccaat gttgcgtttt ttccagcaaa agaaactgtt ttaggatttt cagggtcatg
    32941 gataccgatt ttttcatcca acacttcatt aatacggtca gctgaagctt gtgcacgagg
    33001 caccatgata aaaatagcgg aaagcatcat aaagctgatc aagatctgca tcgcataagt
    33061 cataaatgca atcagattac cgacttccaa agtcatatct gctatgtagt gtccaccaaa
    33121 ccaagtgatt gctacgtttg taccgctcat gatcaatgtc atcattggca tcatcaatgc
    33181 gacgatcgta ttaactttga ttgccgtatt tgtataatct ttattcgcta aatcaaaacg
    33241 attttcttca aagcgtgtct tatcgaatgc tcgaatcact ctgacccctg tcaatccttc
    33301 tcgaaatacc aggtttaaac ggtcagtttt cttttgcata cttttgaata atggaacagc
    33361 aaagtacatg attccgccga tcaaaataat cattactggg atgacaacta agaagatttt
    33421 tgtcaactga tgatcttttt gataagcaag tatgctcgcg ccaatcaacg tgattggtgc
    33481 attgatcatc atacgtaaaa acatttgtgt aaccatttgg atttgagtca catcattggt
    33541 cgttcttgtg atcaaagagg ccgttccata tttatcaaac gcatcttttg tcagactctc
    33601 tgatttttta tagacatccg tacgcaattg cttacccagt ttctgtgatt cacgagtagc
    33661 aaaaaatgta tttgcgatag cagctaagat actgatcaaa gaaaagccga tcatcacaaa
    33721 acctgtatgc caaatataat cgacatctcc ttgcgctacc cctttatcaa taatattgga
    33781 ggtaagtgtc ggcaaatata aatctgccag tacttggatc accatgaaaa ctgcagctgc
    33841 aattgctgaa gtcaaggaga tccgttttac gatttttagc atctagttcc cttctttcta
    33901 tttatatact ccgtttttca gccaagaaag tttcaaattg aattcactga ttgcttgctc
    33961 tactgagtaa tcttcagatg ttgaaaataa gcgatacgaa tgcgcaattg ttgtaaatac
    34021 agtattcatc actaattgga tcagtaattc caattcatga tcatttttta ctttcagctt
    34081 cgtccgatcg atcaattcaa gcaactcttt tgcatcttgt ttgtgttctt tatgtggatc
    34141 gtgaggcgtt ttttggcgac tcgtatgagg agcgactttt cttgaggcac ggtaatccat
    34201 gttcataaac aagttacgat aaaaagaagc attctcgcct tccaaaatct cataaatcat
    34261 tttagaaaaa taggattcga atcctttgaa tagatcacca tcggattctt tcattagttg
    34321 taacatatct ttagagctgt cacgtctcat tgtctcaaag taataaaaat aaagatcctc
    34381 tttatcttca aaatactgat agaaactgcc tctagggata tccgctaatt tgacgatatt
    34441 agcaatcgaa gcttctttta agggtactct agaaaactcg attctcgcag cctcgattag
    34501 tcttttttgt ttttctttag gcaaatggaa aaatgtctgt gtcggcatat ggattctcct
    34561 ttctttcaag atgacacatt gtcatatgac gctatgtcat tataacacct cctacctgtt
    34621 ttgcaagaca tttgcatagt ttttttcatt atcatccgat acattaaaaa agtgataaga
    34681 ggaatccttc catttgaatt aatgagagtt gcccattaaa atagccacat actaaacaaa
    34741 ggatgagata aatggcccaa tcaattagtg tccaagactt caataaattg cctctcgatg
    34801 ctgacagcat cgttttagat acaagaaata ccttagatta cacaaaaaac cacttaagcc
    34861 actcgctttc tatccccgct gctatcttgc caagacaatt aaaaaatcta gatccaaaga
    34921 aactttatta tattctaagc tatacaggca ggcgatcaga agcattagcc gatcaactta
    34981 ctgctaatgg ttttcgtgct gtttatatca ttggtgggat ggaagctctt cagtcgagtg
    35041 ttgcttgaat attgcttgtt agattcaaaa gaggctgtga caaaaaatcg tgtcacagcc
    35101 tcttttatac cctgtctttt tttagttatt tattcttcaa ccttatcaat atgacttgat
    35161 agccttttct ttttcgagta aactgatttt gttagtcata gttataacaa tcatagcaat
    35221 aaaaggagaa ggtaagcata tggcatctgt tttagtagtc aaaggtcatc ccctaactgc
    35281 agaagaatcg cgcacagtta aggcattgac gtctttttta acaagttata aagaaaatca
    35341 tccagatgat gaagtgactg ttttggaact ttatcgcgat gatattccgg aaatcgatga
    35401 agaattatta tcaggttggg aagcattacg tgctggtgca gaattcactt ccttatcaga
    35461 aagtcaacaa caaaaaattg ctcgtttcaa tgaattgact gatcagttcc ttgctgctga
    35521 taaaatcgtt atcgcaaacg ccttatggaa tctaaatatc ccaacaaaat taaaagcttg
    35581 gttcgatacc gtcaatgtag ctggaaaaac gttccgctat acagaaaacg ggccagaagg
    35641 attagtgaca ggtaaaaaag cactgcacat ccaatctaat ggcggtgtat acaacggaca
    35701 agactttgcc tctcaatatg taaaaggtat tttaaacttt gtaggcatcg atcaagtaga
    35761 tcagctattc atcgaaggaa tcgattatga ccctgaccgt gcagatgagt tgatgcaaaa
    35821 tgcattagat aaagctgctg ctttaggtaa atcattttaa aaattgagat aaatgcatac
    35881 aaaagagaca gaggaaaaaa tcttcaaagc agcatttgtg ccttggatat tttcccatct
    35941 gtctcttttt gttattcttt ctgctttttc aacggatttt cttcataaag agaagagatt
    36001 gttgtgtacc attcaaaaac atgagtaatc actactttag ctgctgcata aacaggaatc
    36061 cccaagatca caccgatgat tccgaacaat ttcccagaag tcagcagaac taataaaatc
    36121 gttactggat ggattgctaa ctgattccct agtactaatg gagagatcaa gcgtccttct
    36181 attgtctgct ctactgcaaa aacgatcagt actttgatga tcatgaatgg acctgctaca
    36241 atggctaaaa agatagccgg aatcatcgct aaaaatgatc ctaagtaagg gatcaggttt
    36301 aaaaaacccg caataatccc caacgtgaca gcatactcta aaccaatgac cgcaaaacca
    36361 atcataaaca tgattgccac agcaaaagcc acagttagtt gtcctcttat ataagaagaa
    36421 acttgactat tcatttcact cagcacattc aacgtcggtt tttgcatgcg tgtcggtaaa
    36481 aatttgacaa aataaggtgc taattgttta ccgtctttca atagataaaa taagataaac
    36541 ggcatcgtca gcagagccac taaaatagtc gctaccgcgc cgacaaaact tccaagactc
    36601 tgaactgtac tcttagatat atcttggatc atatcgcctg ccgaattcat gaacttatca
    36661 cctgctgttt ccaactgttc gcgaaattgg ttgaacagcg ggtcccgcaa aatctcggtt
    36721 aatttattat caatcgtatc tacatattga gggaagttac tgatgaagct cactgtttgt
    36781 tcctgaatct tagggatgat cactacgctc ccccatgcga ttagtgcaac aaccaaaaca
    36841 aacagcccaa tgatactgta aagccttggt acttttcgct tttcaaagta atcaactacc
    36901 ggattcatca agtaatacaa gattcctgct aaaatgatag gcagacctac gattgctaaa
    36961 aattgccaga ttggtgcaaa caaatatgaa acttttgtaa ataaaaagac gatcagcaat
    37021 attaacaata caacaagtaa ggctgtgact acttgattat ttaaaaacca gcgccaaaac
    37081 cacgataccg gtctgttctt cttatttttt ccttccataa ttcctcctgt tagttataaa
    37141 aaatttggct tcccaaacca atagcaggca gtctatgcgg atgaagatag attccatttg
    37201 caatttgtcc ttcttctgga caagcatcaa aaatcaatga tacgtgagct actgtcttta
    37261 aattcccatt ggccatcgga ccgacataat cgatcgtata tacctgatca tcaaaagcaa
    37321 ttgttccgcc tgctttcaaa gaaaaaggtt cgtcttttga tacttcttga atcaccgaat
    37381 attttcgtaa ggcagctgtt gctgttttat cgaacaaaat cagcatgggt tcttccttgt
    37441 ttattgcttc tgtcccaatt tctgtaatct ttgcctgaat cattgcactc tctcctttaa
    37501 ttgctttcaa aaacagtata acacattctc attctttagc cgtgtggaat aattatgtga
    37561 tagaataaaa acgaaaacta tttcattaca attaggagga atcagctcat atgatcgaaa
    37621 agataatttt aggaacctat acgcgtcgcg aaagtaaagg aatctatacg atcgaccttg
    37681 atacagaaaa agaagaatta gccaaccttt cattagctgt tgaagaaaat agccctacct
    37741 atgtagcaaa aagtaaagct ggcaatcttt acacagttac tagtgtggat ggattaggtg
    37801 gtgccggtgc gtacgataag gattttcatt ttttgaatgc ggtaacagag tctggcgctc
    37861 ctttgtgtta tgtagcggtt gatgaagcac gtcaattact atacggggcg aactatcata
    37921 aaggtgaagt aaatgtctac catatattag gagatggcga actgaaagca gcagattcaa
    37981 tattccatca agaagcgaca ggtcctcata aaaaccaaga tcatgcgcat gtccactata
    38041 cggatctgac tcctgaccaa cgattagtcg tatgtgatct tggtacagat cgtgtgtata
    38101 cttatgatgt gtccgaaaac ggcaaattga atcttgtaac taccttcact gcagagccag
    38161 gaacaggccc tcgccatctt gtctttcatc caaatggaca attcgcttat ttatttggtg
    38221 aattagacag cacagtccgc gtgctttctt ataataaaga aacaggtgct tttgaagaat
    38281 tacagaaaat atcgaccttg ccagaagaat tcgacggtga aaatggaggg gcagctatcc
    38341 gcatttcaaa tgatggcaag ttcctttatg cttctaaccg aggacataac tcgattgctg
    38401 tattcgcagt ttttgaagat ggttcccaca ttcaaaacaa gcaaatcatc tcaacagaag
    38461 gggattttcc ccgcgatttc gcactagatc caagcaataa ttttgtcgtg tgtgccaatc
    38521 agaacaccga taatctgaca ttatatcgcc gtcatcctga aacaggatta ctggaattac
    38581 tgaaaaaaga tgtctatgta ccagaatgtg tctgtgttta ttttgatcgt tagtaagaaa
    38641 aggagaatga aatgaatcag caagacgtat tagacagact acgggaagaa ctaaatattc
    38701 ctttctttga tgggaaaatc gaagataaag agtatagcga agaggaatat cagaaactca
    38761 aagccgattt acagaactac tttgaacaat atgtacagaa tgtagaaaac taatcagctt
    38821 tccatactat ctgaaaagaa catcaggaca agacttttcc gtctatcctg atgttctttt
    38881 ctacaaataa aaaaccgccg agatggttag actcgacgga aaaggagtat ttactcgatt
    38941 ttgagtaagt acaaggttgt tgttggttat aggtatgtca ttatcataaa ggattttgat
    39001 cactctatca taaaggtaat attacattta tattagataa ctctagtttt tattgttatc
    39061 aaagatttct tttatttttt caacaacaaa ttagtcattt tttggatggc agctgtcaat
    39121 tggtctgtcg cttggtcttg ttttgcttca gatgtattga atagatcttc atctacccct
    39181 gattcaagat cgatactttg gatcatttct tcacagcctg ctacatatga aagataagct
    39241 ttttcaaaat ttttatgaat gcccattgct tttgctggtg gacgcaaagt actgactttc
    39301 ataagcattg cccgatattt ttttgttcct tcttcaaata acaggatgat ctcttcaaga
    39361 gtcgatttgt ccagttcact tgtttttcct tcatcaattg cgtttctgat cacttcatat
    39421 ttcggatgca ttccttctcc gattgcttct gtttccttga cgatttgatc gatggactgc
    39481 acataatagc caatattcgg taacatgttc gttttcctac tttctccatt gttgttatta
    39541 tttattctac ttgtttttat cctcaaatga caagtacttg aaaaaattta atggtttcta
    39601 tacagctcgc cattcttatt cgtgctcaaa gaaaccatct gctaaactat attgtttccc
    39661 tgcgacaatg tcatattgga tcaattgata ttcgtcgtaa atctcttgtt gcgagcgatt
    39721 gaattgcgct tctttatacc actgtccgtt ttgatagtac agttctcgtt caaacgccgg
    39781 aagttcctgt tctaatgata aaagcagctg ataaaagcca tttgttgtct gattcgtctg
    39841 ttccattaga ttcgctgcaa aataaaacgg actggtgatt gcatcgtgag tcgtttgctt
    39901 ttctaattct cctttactgt cgaacataag aaattgtgtt tcatgcaatg tttgtttgtc
    39961 attttttgct tggatcgtat ctgaatagat ccctggaaga tgatcccccc aaaaaacaac
    40021 taaagtcctt ctagaaagat tcttcaattc ttccgtgaac tgcttcagtg ccgtgctgct
    40081 ataggaaata tcttgcagat aattctctaa gtcaagtgtc ccacttccat ctgaagtttt
    40141 tgcaggatag tctagattat catactttcc atcgtagggc atatgtgtct gcatcgtgac
    40201 taaatgaatg aactgaggtg ttttttcttc cttgagaagt gtcattactt ctttgtaagc
    40261 tgactcatca gaaatatatg gattattctc tatcgtatcc gtataggtca tcgtacgctc
    40321 gctgatgaac tggtcaaatc ctaatgtctg ataaacatcc tctcttttat acatcgaagt
    40381 attgtatgga tggatcgctg tcgtctggta tgattgtgcg tttaacgctg aaacgataga
    40441 aggaagctga tccatttttg gtacaagcat cgtgtaaggg gtggtgagtt gcgcattaaa
    40501 taacgccata gaaaaaccag tcaatgcttc aaattcgata tttgctgttc caccgccata
    40561 gttttgagaa agcatattgc cactatatgt ttgatcagct acttcataat aatctgccaa
    40621 tggctcacca gatacttcta cgccgtttaa tcgactagga tctgagaaac tttcactcat
    40681 cacgaacacg atgttcggcg actcttcctc tacagtttta tttttttcat cggctagctt
    40741 ctggtatttt tcagtgattt ctttgatctt ttctttcgaa tatccttcag gttcatccat
    40801 tggttctacc ttcagattgt acaaaaaccc accgataaaa ccagtgttat agtagttcat
    40861 tttctggctg taaggtatcc atagtgccgt tttattatat gcttttcgca acaaattatc
    40921 gggattgttg aaattactga tataccctag cagtccaatt gccacaagca gtgtcgttaa
    40981 tcggatcaat tggaatcgcc ttcctttttt caggcttcga aacatgtacc agcaaaacaa
    41041 tcctatcacg gttcctgcgg cagctaagat cactgtaaac agcatagtgc cggtcatatc
    41101 tttcagcaat ccgatttcag tgatcatctt caaatcgtct ggataaatcg gttcttgccg
    41161 ataactcatt ttcatataat ttgcaaaacc taatacaccg atggctacga catacgtaag
    41221 ggaacctaaa gggacagatc ctgctagtgc aatcagaaaa ataagaataa tcagcaagac
    41281 gagacaggct aagaagaatt tttccgtatg ccaagaaaaa gcaaatttca acgcaaggtc
    41341 tacggataga tcattttgac accactgcaa aaataaatta ctaaaaacaa caagaaaaaa
    41401 gatactgatg attgctgctg ttccttttaa aatctttttc tgtttggtcg aaagtctgct
    41461 tatatatctt ttcaaatgct tgctccttca tttctatcaa taaaagaatg ttgcttctct
    41521 tattttagtt gtacgaaatt cgaaagtaaa gaacggaaag aagaattaat gaaatccaaa
    41581 tattctcttt ctttatggcc tttctggttt ctttaataag cggacctttc gtactccaga
    41641 aattttttct agctgttgtt tcacttgatt gagctgttca aaatcagtac tgtctatgtc
    41701 aatcaatatg tagacatgct cattcttatg gttacgcgat atatctgcga tcgctagctc
    41761 gttctcattc agcagagaaa atatctctgc taatatattg gttttctttt gataaaatat
    41821 agtgaatcga aacggcgctt ggaaaaacat tcgtgcggat ggataattga ccgcttctct
    41881 aaccgtaccg aacaaaagat aatcttttaa ggcttcaact gccaaacgtc cgctgtctgc
    41941 caaagcttcc tgagtcgatc cccctagatg aggcaacata agtatacggt cattttctaa
    42001 gaactcttct tctggaaaat cagtcaagta tttagccaga tgttgttttt ccaatgcttg
    42061 cataacagca tatttatcaa caatttcact tcttcctaca ttgataagta cagcatcttt
    42121 tttcattttt tctatattcg cctgatcgat caatcctttt gtatcttctg tcaacggcag
    42181 catgactacg atgtaatccg aggtagaaag aactgtttct aaatctgctt gccgaacata
    42241 atccaactgg gcatcgcgga tagaataacc caagacatcc atccctaagc tatagcaact
    42301 tagcgctact tttgtgccta tcgctccaag accaagaaga ccgatggttt tgccttgcaa
    42361 ttctcgtccc acataagcac ttcttttgtt ttctgcctgt tctaaaatat taggacctgt
    42421 tagtgtttgt accatacgac ttgcttcgat tatcggacgg gaagataaga gcaaacagca
    42481 caaaacaagc tcttttactg cattagcatt tacacctggt gtattcatga cgatcgtccc
    42541 gttttcagaa gctttttcaa cgttgatcgt gttcacccca acaccagctc ttgaaattgc
    42601 tagcaaatct ggtgtaagcc attcatcttt cactttcgta ctacgaataa ctattccttc
    42661 ggctggcaaa tcatctatta ttttgaaata ttccccttgt aacttttcta tctcttgttc
    42721 tggaatagca tcaatcaaat gaacgtgata cataaaaccc cctccttact aacaagtatc
    42781 tcgaaatttc tgcaattaga caactgttta ccatttgact tcctagaagc aaaaagagca
    42841 gttagagcag agtaggctga gtgataaaaa taaggctatg acaagttact gccataagcc
    42901 ttattttcga gagcaaaata ttgagggtga gatatcttga taaatggtgt tccgttagct
    42961 gacattgata ataagactaa atttcaaaaa agttgaaaag caaatttcgt caatctcttc
    43021 ttatttctta aaactaagtg gctttttcac aacctctttt tatctaataa ccactgtttc
    43081 caactcaact aattttgccc acgtttcaat ttgatctgtt gttagattta gcgagacaac
    43141 ggtatgatga ccgccacctg cctgaatcca tgaatggaca ccttcatgga aattcggttt
    43201 agttttccat aacacacgtg caacaggtaa attaggtgct tcagtcgttg gttcaaaggc
    43261 ttctacttca ttgatcagca gtttataatg cgtaccgaaa tctgccatcg atacgactac
    43321 cccttctcct gctttcccat caaatacaag acgcgccgga tcttctctat ctcccattga
    43381 taaaggagaa acaacgattc ttggtttcgt cgcagcaagc gtcggatcta cttccatcat
    43441 atgggattcc aagattgctt cttggccact agctagctcg taagtataat cttccatgaa
    43501 tcctgtatct ttccctcgag ccatgatttt cagcaaccga tcaatcgctg cagttttcca
    43561 gtcgccttcc ccagcaaaac cgtatccttc tgccatcaaa cgttgtacag ctagtccagg
    43621 tagttgtttc attccataca ggtcttcaaa attagtcgta aaagcgttat agcctccttc
    43681 ttctaagaaa cggcgaatac cgatttcctg ctgagcttgt acttttacat gttcctccca
    43741 tgtcttttct tcataatcac catagtcgaa ggtatacaat tccttgtact cttcaaataa
    43801 ttgatcgact tcttcgtctg atacgcgatc gattacttgt acaagatctc cgataccaaa
    43861 ataatcaaca gtccaaccaa attgaatctg tgcttccact ttgtctcctt ctgtgacacc
    43921 cacgtttctc atgttgtcac caaaacgagc cacttttatt ccaaaacttt cattataggc
    43981 tactgcaaca tccatccaat cagcaatctc tttttggatc tcaggtcgtt tccagtagcc
    44041 aacgacgatt ttattttgtt tatttaatcg agcattgatg aacccatatt cgcggtcacc
    44101 atgagcggat tgatttaaat tcatgaaatc catatcgatc gttttccaag gaatgctttc
    44161 gttatattgc gtagctaaat gaagcaatgg tttttgtaga agctttgtcc cgcggatcca
    44221 catttttgct ggtgagaaag tatgcatcca agtgatcaca cctgctactt cttctcgata
    44281 attgacctct ttcatgattt ttgtgatcgt atcagcagta actgctaatt cttgaaggcg
    44341 gattggataa ggcaattggc cattttcatt cagttcatcg accatttctt gtgcatgttt
    44401 ctttacttct cgcagtgctt cttccccata taaatgctgt gatcctacaa caaaccaaaa
    44461 ttctttttct ccaatattca acataattag ccactccttt tatttgtttt gtccgtaata
    44521 cgcatttttt ccgtgttttc gtaaataatg tttatctaaa atccgttgag gcagctcttc
    44581 tgaaaatgaa ttgagctgtc tggtaaataa attcatcttg catacttcat ctagtacgac
    44641 tgcgttcatt accgcacttt gcgcatcttt cccccaagta aatggaccgt gtccgtgtaa
    44701 aagtacccct ggaattgcta agggatcaat tttgcgttct ttgaatgttt ctatgataac
    44761 ttttcctgtt tcatattcgt acccgctgtc gatttcctgt tgtgtcaaaa atcgagcaca
    44821 aggtaccgat ccataaaaag tatctgcatg cgtcgtcccc atcgcaggaa catccaatcc
    44881 tgcttgtgcc cagatcgtcg cccatgtcga gtgagtatgg acgattcctc cgatttgagg
    44941 aaatgaacga tataaaacag catgagtagg cgtatccgaa gagggattga gtttaccttc
    45001 aatgatatga ttgtccaagt ccacaacgac catgtcgtct gctgtcatct cttcataact
    45061 gactccgcta ggtttgataa cgaaatatcg tgtttcagga tcaaaagcgc tcacatttcc
    45121 ccatgtatat ttgacgagtc cgtgtttagg caagtcaaga tttgcttggt atacttcttc
    45181 tttcagttgt tccagcattt tctatcactc ctttttcttg caattgatga atcgctgttt
    45241 tttcaatgtc gatcccctca cggtaacgtc tcataaatat ctgatagcct gctatttctt
    45301 ctgctgaagg tgtgatggtg attccttggt cttgtccaaa cacgtcttct gccaagaagt
    45361 tttctaaaga cttcccatgt cgatccatca tataggctgc taataacgcg attccccacg
    45421 ctccaccttc tccggctgtg tccatcactg taactggtgc ctccatagca gatgctagaa
    45481 tccgctgtcc aacttctggt gttttaaaaa tccccccatg ccccactaaa cgatcaattt
    45541 ggacattctc agatttcaat atatccattc cgattctcat tgcaccaaaa gcactggcta
    45601 aatggatccg catgaaattc gctaaatcaa aacggctacc tggtgtacgt acaaataatg
    45661 gccttccttc atttactcct gtaatgtttt caccggaaaa ataaccataa gaaagtaatc
    45721 ccccgcaatc cgtatcgcct tctagcgctt tgttgaataa taccgtgaat aatttatctc
    45781 tgcttatctc catacccaaa gaattggtaa attcttcaaa aatactgacc caagcattga
    45841 tatccgaaga gcagttattc gtatgaacca tgcctactag ttctcctgaa ggtgtagtga
    45901 ccatgtcgat ttccggatgg acattttcta gttctttttc taatacgatc atagcgaagg
    45961 cggaagtacc agccgaaatg ttccctgtcc ctttggctac actgttcgta gcgaccatac
    46021 cggttcctgc atccccttct ggcggacaaa ccgggattcc tggtctcaaa tttcccgtag
    46081 ggtcgatcag ataagcccct gattcgctta acttgccagc ttcttctcct gctactagaa
    46141 ctttaggcaa aatgtgatcc aagtcaatcg ctacgtgcgc tttttcgatt aactgaccaa
    46201 aaatattttt catttcttga tggtaggttt tcgttgaagg atcgatagga aacatgcctg
    46261 atgcatctcc tacgcctagt actttctcac cagtaagctg ccaatggaca taacctgcaa
    46321 gcgttgtcaa aaaattaatt tctttcacat gttcttcttt attcaaaata gattgataca
    46381 aatgagcgat actccatctc tgcggaatat tgtattgaaa tttttccgtt aatattcgtt
    46441 ctgcttcttc agtgattgta tttcgccaag tacgaaatgg tactagtaac tgttccttgc
    46501 tatcaaatgc tagataaccg tgcatcattg cactgaaccc aatcgacccg attgtcgtaa
    46561 gattctcgcc atagatttcg aatacttctg ctgccatttt tcggtaactg acgcgcagtc
    46621 ctttccaaat atcttctaat gaataggtcc agataccatt ttctagtttg ttttcccact
    46681 cataactacc agcggcaata ggagtaaaag atgaatcaat caatacagct ttgatcctag
    46741 ttgatccaaa ctcaatccct aaagatgtac gaccatctat gacatctaac atactttgcg
    46801 catttacttc cttcataatg atttaactcc ctccttctcg tcaaacctga tcaaaccgtc
    46861 tttttagtag cgcttacaat gattattgta tacttttgta cgtacatgtc aagcagttat
    46921 ttacaagaat acaataaaaa acacttgttt tgtacgtaca taagttataa aatgaaattg
    46981 cttacaaaat ctgatcaacc gccttctcga aattctagaa ggagagaata cttatgaaaa
    47041 aagaaaaaaa agtttcctca tcgtttattt atttttttgg cgcatttggc ggcattctat
    47101 ttggatatga tattggtgtt atgaccggcg ccttaccttt tttacagcat gattggggtt
    47161 tggcaggtaa agcttctttg ataggatgga tcacgtcttc ggtcatgtta ggtgcgatcc
    47221 ttggcggctc tttatctggt cttctttctg ataagcttgg acgacgaaaa atgattcttc
    47281 tttctgcact tatttttatg gctggttctg tcctttctgc atctgcccct cacaatggtt
    47341 cttattttct gattgcagca aggattcttc taggtttagc tgttggcgct gcatctgccc
    47401 tagttcctgc ttatatgtct gaaatggctc ctgctagact aaggggaaga ttgtcaggga
    47461 tcaatcaagt gatgattgct tctggcatgc tcctttccta tgttgcagat tatttgctaa
    47521 aagggttgcc tgaaacgatg gcttggcgcg tgatgttagg gctcgctgct gtccccgcgc
    47581 tgattttatt tttcggtgtt ttagctctac cagagtcacc gcgttttctt atgcaatctg
    47641 gccgcttgga agaggcaaaa agagtattga actatattcg gacaccaaaa gaagctgaac
    47701 aggaattcga acaaatccag ctgaatgtca aacaagaaaa gacaaccgga acttcttggc
    47761 atactttgtt tttagaaaaa tatcgttcct tagtcattgc cggtattggt gtagcagtat
    47821 tccagcaatt tcaaggagct aatgctattt tttactatat tccgctgatc gtagaaaaag
    47881 cgactgggca tgcagcgagc gatgcattga tgtggccgat catccaagga atcattttag
    47941 ttgctggttc tttgctcttt ttggttattg cagacaagtt caatcggcga actttattga
    48001 aaataggcgg tagcgtgatg ggactttctt tcatcctacc agctgtttta ggaactgtac
    48061 tggatgctca tacaaattcg ttgttgattc tcttgttttt atgtatttat gtcgcatttt
    48121 attcttgcac atgggctcca ctgacatggg taatcgtagg cgaaatattc ccactagctg
    48181 tccgcgggcg agcatctggc ctagcctctt cttttaattg gattggttct ttcctagttg
    48241 gcttgctttt tcctgtgatg actgcttcta tgtctcaaga aatcgttttc ggcatttttg
    48301 ggatcatctg ctttttaggg gttttattta ttcaagagat cgtaccagaa actcgtggga
    48361 aatctttaga ggaaatcgaa caaagtgcat ctaaaaaaac ttatcctaaa cgtatttcta
    48421 tccatcattc ttaaagaggt tgtgacagaa gtggtcagct tcaagaaata agaaggaacc
    48481 gcttagtttc cagtcacaag gaacaatttc aaaaaacagc ttctcatgtt tgatgaatat
    48541 tgtgacttgt gaccagttgg taggagaaca ccgtttagtg gagaggtggt gaaagaaacg
    48601 ttcagccttg agcgatgaca aaagctctca caaacattgc gacgagtaac cgtaggagca
    48661 ataagaggcg gtaaaaaccc gtctcttatt tttcgttttc tttcactgtt tcccgttcaa
    48721 ctagtacagg ttcatagaga atatttggct gtgcctgtcc tttttcaatc gttgtgacga
    48781 tccaccgtgc ggcatcttgt cccaactttt cttttggatg cgtcaatgtt gtcaattttt
    48841 tattccctaa atggcttaaa gaagaatcgt ctgttcctac gatcgatagg tcatctggaa
    48901 tatgatagcc attttctgtc aacttatcta gcattaaact agctatttga tcgttatagc
    48961 aaatgatgcc atctaaagct tgttcttctt tcaaccgttg tactgttttt tcagcgattg
    49021 tttctcgtgt ttccgtggtg aaagtaatga tatcttccgt caaaaaacgc acattatact
    49081 gttcacacgc gctgataaaa cctttcatcc tgtattttcc ttgaagatcg tcgatttttg
    49141 tgatgaacaa cagacgctga tgtccttttt ttatcaaata ttctgctgcc ataaaaccga
    49201 ctttcacatc atctaaacaa atataagagg catttaactc ttcataagca gcattgatca
    49261 tcaccatcgg aatgccttgt tctctcaaag caacataaag tgctaagttt gggttatact
    49321 gattactttt cgtaggctca acgatcaaac catctacccc ataagcaatc attttcttca
    49381 aacactcttt ctccaattcg tgatcgttat tcgtactggc taaaagcaat gaatacccag
    49441 attctcgtaa ttcattttcg attcctcgga taatcgacgg aaaaatataa tcagagagat
    49501 atgtggtgat gacaccgatc gtttttgttc tgttcaatgg tgttttttct ttcttatagc
    49561 tgtcatctac atatgtgccc gacccttttt ctttacgcag atagccctca tttaccaaca
    49621 cagcgattgc ttgccgaatc gtatgtctgc tgacgtcata tatttcttgc agcttgaatt
    49681 ctgagggaat ggttgtattt acttcgtatt cctcacgaag gatcttttgt tttatctctt
    49741 ctgcaatatc ttgatatttt gccatttgcc ttgccccttt ttatttgtac gtacatatat
    49801 cataacgagt ctgcaaggtt tattcaagca aaaatcaagg tttcttgtgc tcataaggca
    49861 tacggaacag gttcaccaaa ttctggaaat ccttgctcat tccacgtaaa gcattgcgcg
    49921 ttcgcgtgcc gattaggatt gtctaacgga tccccttttt ggttcttctc tggtcgagca
    49981 tgatagatca aaatatcaaa gcacccgtct tctgaaaccg taaacgagtt gtgaccagga
    50041 ccaaattgct tatttttttt agaagaaacg aatactggct ccgataattt atgccatgat
    50101 tcttttaata aaagattctt gtgctcatca gcccacagca ggcccatggc atagttttca
    50161 tctgttgcac taccagaata cgtaatgaat attttcccat tgcgagtaag gactgctgga
    50221 ccttcattta ctgaaaaacc ccgtttttcc cattcatact caggtataga aaggaggatc
    50281 tgcttcccct ttaacgtcca aggattatcc atttcggata gataaagatt agaattccca
    50341 gtaatttcag gatcttgttg ggcccacaca taatatagct ttccttgaga agagaaagtt
    50401 gttccgtcta aactgaaagt ttcccttttc gtttttattt gtcccttttc tatccaatct
    50461 gtattcattg gatctatatg ctgattttca agtacgaaca tgcggtgatg atgagattca
    50521 tcacgtatag ttttatgatt gcttgcagca aagtaaatat accattttcc attgatataa
    50581 tggacttcag gtgcccagat caattcactc atcggtcctt cttcatgagc ctgccataca
    50641 atcaggcttg cagcatgttc taattcattc agtgactttg cccttcttaa ttcaatcact
    50701 tggtagcctg gaaccgatcc tgtaaaataa taataaccat ctgtatgttt atatacccaa
    50761 ggatctgccc gttgccgaac gataggatta ttataaagtg tcttcatcat aacaaatttc
    50821 ctcacatttt ctttattcta attacattcc aagagtattt ttctatccct acatttaatt
    50881 cgtcatgttt ttctattgaa aaatagttta tttcaggttt tattttttct ggttcttcac
    50941 gtgtattttt gtccaacaga tcgctactgg ttaatgtgta gtgctctcct tgatctagca
    51001 aattgaaatc atgttcaatc gttatctttt gttgttcatt tgtgcgattg atcaagaaaa
    51061 tagtcagctg attgccgtta tctacgatca cactgtccac ataaggaaca ttttttatct
    51121 tttcacaatc ataaacaggg caaatgattt gttgtttcaa tacttgacct ttagcatatt
    51181 tcgataagtg ttgcatcaca taataagttg gattcctcca tgcttgtcct ttagcatctg
    51241 tcagtattaa aggtattgtg tttactaaca atgattgaca actaatcttt acgcgatctg
    51301 cgtgtcgtaa aatagccagc cctaatgaac caaataataa tgtatcttcc atagtaaagt
    51361 aacaccaatc gatgggacta ccgacttcaa aatccctatg tcttttttcc ggttgggcat
    51421 gtacattcca ttcatcaaac gctagataca ttgttttctc acttctcaaa tatcctttta
    51481 cataatcaca agtagcaacg atttcttcaa tttgacgatc gaatcgataa gcttttgcaa
    51541 ggtatgtcgc tgtatcatca cgctcatttt taggaggttt agtcaagtct tcttcatcat
    51601 acttatcaat atagttatgc aaagctaaat aatctacatt ctcataagct tcttctaatg
    51661 cgatacgatc ccattcaggg tacgatggta aacgtggcgt agagcttcca actaagattg
    51721 tttcaattga atcatccact aacttcatga cttttgaggc ttcatttgct aacctaccat
    51781 attcataagc actcttagcc cccacttgcc atggaccgtc tagctcattc cctaaacacc
    51841 ataatttaac gccaaaaggc tttttttgcc cattttttat tcttaaatca ctccagaagg
    51901 ttccttttgg aaaattacaa tattctacta aattttttgc ttcatcaatt ccttttgttc
    51961 ctaaattcac cgtgaatatc ggtttcgctt gtacatgact gatccattta aaaaattcgt
    52021 ggagtccaaa agaatttggt tctatacctc gccatgctaa atcaattttt tttggtcgtt
    52081 gttctttcct acctacagta tccacccaat cataaccaga tgtaaagttt cctccaggat
    52141 agcgaatgac acctaattct aattccttta cataagagag gacatcttgt ctaaacccgt
    52201 caccatcagc tgtttcatgg cccggttcat aaatccctgt atagacgaca cttcccatat
    52261 gctcaacaaa tgagccaaac agccgagaac tgatctctcc taccgtaaaa tcctctctga
    52321 tttttacttt cacttcttcg tccaacagct ttccctacct ttcatttcct atagtcaaga
    52381 taatagatac aagtttccat acgccaccag caaagataaa aataaaagga gggaaaagaa
    52441 atatgagcag tacaaatcct aataacaata cgcaacaaag aatatttctc aaaaaatcaa
    52501 aaaatacttt ccatgcactt tgttcaaaaa tttgtaaaaa tgtgatatct ttgttttcag
    52561 aaatcacata tatccaggat aaaagaaaca tggaataaat aagtaaaact acatatccac
    52621 taattgaaag tacgattgtc tgttcttcta ataattgatt aacaagaaaa taaataatga
    52681 tcgttaacag actaaggaac aagttcttac caaaatgttg ctttattcct tgaaagaaaa
    52741 aataaatgat atttcctgat ccctcacctt tccattgcgc cattacataa aaaacagcac
    52801 atgtagcagg cacgatagta ataacaggca aacacacgat tacccagaga atacctaata
    52861 agatgtaatc agaaaccaca atcaactgtc cataaagttt agtctcaact attttcatct
    52921 tcctcactct ttcattccag acatagctgt tccttgaaca aaatatttct gtgcaaaaat
    52981 ataaaccact agtaatggca gcattgaaat aaccgttcca gccattacag gtccataaaa
    53041 agaaatgttc tgccctgtaa ataaagctaa ccctgctggt aaagttctca tttttgaact
    53101 acttgtcaat atcaatggat aaagcaagtc attccaacta ttcatcagcg tgaaaatccc
    53161 taatgataaa agagtaggtt tgctcaatgg caacatgatt ttcaaaaaaa tattaaactc
    53221 acttaatcca tcaatgcgtg ctgcctcttc caaagaatct ggtaaagtaa taaaaaagga
    53281 acgcatcatg aagataccaa atgcagttgt catacgagga atgatcaaac ctgcataagt
    53341 atcaagcatg ccaagcaaat tgacttcaat aaatagagga atcatgaaga cttggaatgg
    53401 gatcatcatt gtcagcaaaa cgaaatagaa caaaactgat tttcctttga aacgcatacg
    53461 agcaaatgca taccccgcaa gagaatcaaa gaatacagaa gtgatcactg tccctccagc
    53521 aaaaatcact gtatttttga tgtaatctaa taaagggatc gttgtccaaa ccttaatata
    53581 gttatctagg gtatagctat ctgcaaatat tctaggcgga aatgagataa tgtctttttc
    53641 gtgtttaaaa gaagaaataa tcagccacaa aaaaggaaac gcaataacca acaatataac
    53701 tagcatacta atcgttcgaa tgattttttt accactaact gcttttcgac tattcacagt
    53761 aactgtaatc gagctttctg gtgccataca ggtttccctc ctatttcatt tgtttttctt
    53821 tccgtgacat gtacacatta gtggagatag ctatagttgc aacaatgata aacaaaaccg
    53881 aagacagtgc tgatgcatag cccaattcat aaggtgctgt aaatcctcga ctgtaaatat
    53941 attgaacagc tgtttctgtc ttaaattgtg ggccaccagc ggttgcaaca tatacttggt
    54001 caaacacttg catcgaacca atcagattcg ttaaaataca aaaacctaag gagggaacga
    54061 tctgaggtag cgtaatgtta aaaaactgct gtcgatttgt tgcaccatcc atttgagcag
    54121 attcatacaa agagggagag attccctgaa tagcagtcaa gagaatcgtc atagtaacac
    54181 caaaattctt ccaaacagtc atgatggcta ccgtcggcat agcaagggtt ggatcgcgaa
    54241 aaaattgagg gatcggcaag ccgacttgtg aaaacaagta aggaatcgcc cctacattcg
    54301 gatcaagcaa catagaaaaa ataatcgcaa ttgacgtcaa tgaacaaata actggaatgt
    54361 aaaatgtcga acgacaaaaa cgattgaatc tggtattttt agataatgct actgctgcta
    54421 ataaaccaac gataatttgt gttggcgttt cgagtacggt gaaatataaa gaatgaatca
    54481 acgaattaac tgctcgttca tcactaaata tacgtgtgaa attttcaaaa cttacaaaat
    54541 ttcttgatgt aaagaaaata ttcaaatctg taaaactaat agcaaatgtt cctaaaagcg
    54601 gtatgacagt aaataataat aaaactaaaa aagatggagt taaaaacaaa tacgcagcac
    54661 gatcaggacg attccaatat ttggtgaatc cgttcatata gtccacctca tctttcattt
    54721 tgataaaata tacaatcttg gtttaaacga atctgaataa gatatccgaa caatcgctgt
    54781 gatttttgca ataacaccta tctgcaaata ctaggtcgat cattcagata tctgtatctt
    54841 gccaacagtc tatcctgtat aaagttctgt actatttttg cagtaattga ttgatggcat
    54901 catctgcatc gttcatgagt gtctcaggat cttctcctgc taataatttt tcaatcagtg
    54961 gattgatgat atcgttattg atcgcagaga tttgggtaaa acctggtaaa tatggctctg
    55021 catagtccat ttgtttcgat aattcagata caataggatc attttttact tcttcatctt
    55081 ttgctactga atccaagtag gcaggaaaac cattttcgat actccatttt ttaccaattt
    55141 cagttgtatt ccaatatttc aaaaactcat agacagcttc ttttttatta ttatctgtac
    55201 ttgccggaat ggcatatcct acgccatcta aaatagctgt ttttttgtct gaatcactcc
    55261 cttgtggtaa ggtagtcaca ttataatcaa tctcgtttgc tttcaatccg ttatttaacc
    55321 atggcccatt gatttcaatg gctagttgac cagcattcat taaattgtcc atttcggcgc
    55381 cagaaatcga ttctggacca gtcttgtcta catggatcat tttttggatc gcttttaacg
    55441 ttttaaggtt ctcaggagac gcaaattcag acttagtata atcatcgttc actaatttac
    55501 cgccatttgc taacatccag ttatataacg gtgcagttcc atccttattg aagacaaaac
    55561 ctgatacatt tttactacta tcagttaatt ttggtgccat ttctgtcaat tcttcccaag
    55621 tagtaggtgg ttgttcagta tctaatccag cttgtttaaa caaatcatta ttccaataca
    55681 tatacatgcc ttgtacctgc atggggacaa aatactgttt accttctact tcacctaatt
    55741 caatagccgt ttctttaaaa tcagatttat ctactccatc atattcccag aaatcgtcta
    55801 atggttgtac cgctccgttt tctacatact gtgcaaaatc tggataattt aatgcaataa
    55861 agtcaggtgc ttttttagaa gaaatcgctg taggaagttt ttcattcaaa ttggcccaag
    55921 tcatgatatc catttcaatt ttgatgtttt tatcatttgt tttattaaat tcattaacga
    55981 tttcttgcaa tatttcacca tcagatgcag taaacccatt ccaaaaagtc aaagtcactt
    56041 ctttatcaga atcagattct gctgaacttc cgccaccgca agctcctaaa atacctgttg
    56101 cagctaccaa caaagagcca attaaccatt ttttaccttt cattttttgt tcctccttca
    56161 tctgataaac gacatctgac cacattccaa gatagcggtt tcaataaaca attgattttc
    56221 ccatcttcag cttttacatt tgttgaatga cttggtttta cttgttcact tttaggaaga
    56281 ttagttgctt ttgtatcaaa tccactcatt tcagaaaaat caatcactcc ctctaatgat
    56341 aattcagaca agtgaacagt tagattcatt tcttcttctc cacggttaac tgcaaatatg
    56401 acaagttctt tgtcatttat tacggctata ctttctaaat acggcacttc ttcaaaatct
    56461 tccgtcgcat agtttgctga acgaatttgt gggcttaaca cctctccttg tccatacaca
    56521 gcagcttgca taaatggata atagatcgtc tgtctccaag cttctccgtt tgtttctgtc
    56581 ctgattggtg caataacatt taccaattga gcaagacaag caatctttac tctatctgca
    56641 tgtttcaata aagtgattaa tagacagcct aatagtaatg catcttcaaa attatagtta
    56701 tcttctagta aaggaggagc aatctgccaa ggcgctgctt gctcatcttg ttccgctgaa
    56761 tgataccaaa tattccattc atcaaaggac aggttgatct gcttcttact atgtttcttc
    56821 gccttgactg tatcgcacat cgctgtcact tcagaaatga accgatccat gtctaaggaa
    56881 cgtgcaagat aatgagaaag atcatttttt tggttgccat aatattgatg cagagacaaa
    56941 taatctattt gatcgtacgc ttgatcaaga actgttaact cccaatcacc aaatgtaggc
    57001 atttgccgat tcgaacttcc gcataaaacc acctcaattg aatcatctac gagtttcatc
    57061 gccttagccg tttcctctgc taaccgtcca tattcttccg ctgttttatg tccaatctgc
    57121 caaggaccgt ccatttcatt ccctaaacac catgtcttaa ttccaaaagg gctctcttga
    57181 ccattcgaac gccttaaatc actccaataa gttcctttag gaaaattaca atattcgact
    57241 aaattacgag ctgcatctac tccacgagta cccagattga cagccatatt gatttcggcc
    57301 cccacatgct gacaccagtt ataaaattca tgaatcccaa cttcattcgt ttcaattgtc
    57361 cgccaagcta aatccaacct tctaggtcta tttgctatgg gcccaatact gtcttcccaa
    57421 cgaaatcctg acacaaaatt tccaccagga tatctaatca tgggaatgtt caattctttt
    57481 accaagtgaa tgacgtcttg gcgaaatcca cttttattag ctgatggatg atctggctga
    57541 taaatccctt catatactgc tcgtcccata tgttcaataa atgaactgta caaccgcgga
    57601 tcaactttgc ctacacgctt gacactacta atcaacattg tggcttccat aactgacctc
    57661 ctttaattta tacatgaata atacacctcg ttgaaagcgt tgtcaataat ataaatgtta
    57721 aacttactta ttttttatcg attttaatta accaaaatat taataatgat taaaacaaat
    57781 aatttaatat aacttttatt aacaaatatg ttaatatata agaaaaacct tttaagaggt
    57841 gatatatatg caactacaaa taaacgaaga atccttaccg gtatatgaag cattagctag
    57901 taaaacaagg atcaagatca tccagctact ttccaaaaaa aagatgaatg tcaaagattt
    57961 ggcaaaagaa cttggagtga gcagtgctat cacgacgatg cacgtgaaaa agctagagga
    58021 agcaaacatc atcaaaacag aaaaagtagg acaacaaaaa atttcgagcc ttcgtgtcga
    58081 taaaatcgat atcagttttc cagaaaaaat attcaatgct tttgatacga aagaaacatc
    58141 gatacctatt ggtcactata caaattatgc aattgaacca acatgcggtt tagctacgat
    58201 ccatgatttt atcgggaaag tggatgaacc acgctatttt atggatcctc gaaggatgga
    58261 tgcccgcatt ctctggttta ccagcggatt tgtcgagtat caggcaccta attttttaaa
    58321 tacagaggat acattggaga tgttggaagt ttctgtggaa atttcttctg aatttccttt
    58381 ttcaaatgac aattggcctt cagatatcac tttcagccta aatggtgtgg agctaggaac
    58441 atggacgagc cctggagatt ttgctgatat ccgcggtaaa tatacgcctg attggtatcc
    58501 agataatctt aatcaatacg gcttgctgaa gacgatccga attaccaaac acttgacgaa
    58561 tatgaatgga gaacccttgt caaacatcac gatcaacgac atccctaaag agcaagacac
    58621 ttggcatttg cgaatcgaag tgaaagacga tgccaaacat gtggggggct gtactttatt
    58681 tggtaaagga ttcggtaatt acgatcagga tatcaaatta aaagtttact acagctgata
    58741 tttttctttt ctattttata aaacaaaaac agccaatccc tatgaaggga cggctgtttt
    58801 tgctttattg ttatttccag aaatcatcca aaacggaaat tggcaaatgt cgtttatgtt
    58861 gtgtcttgtt ccaccatgct tcgatttttt cttgtgcttg agcgggaact tcttttcctt
    58921 ctagataatc atcaatttca ttatatgtga cacctagtgc gacttcatct gcaatcattg
    58981 gtttcccatc ttcaagatct gcagtcggaa tttttgtgta taatttttcc ggtgcattca
    59041 atgcttgaag caattgtttc ccttgtcgtt tgtccaaacg gaataatggc aaaatgtcgg
    59101 ctccaccatc accaaatttc gtgaagaatc cagtaatgtt ttctgcagca tgatctgtcc
    59161 ctaatacggc tcctgctctt tctccagcta cggcatattg cgtaatcata cgttgacgtg
    59221 ctttgatatt tcctttgtta aaatcgctga ttcccacacc tgcttcgctt aatacttgta
    59281 cttgtgcatc aacagctggt ttgatattta ctcgcagact aacatcgggc tggataaagt
    59341 caagagcagc ttttgcatct tcttcatctg cttgttcacc ataaggaaga cgaacagcga
    59401 taaattgata gttttcatct tttgtttctt cacgcatttc ttccatcgtt agttgcgcca
    59461 aacggcctgc taaagtagaa tcttggccgc cgctgatacc tagtacaaaa gttttaagaa
    59521 acggatattt tttcaaatat gctttcataa agtcaatact tttacgtatt tcttcttttg
    59581 gatcaattgt tggtttgaca cctaattcat tgataatttc tgtctgcagg ctcatttatt
    59641 ctcctcctat gcttctgtat gaagttctgc tacgcttttt ttcattcgtt ccatgatagc
    59701 cattttatgg ttccagcatt cagtagacag atcgactggg tatttttgcg gattcaagtc
    59761 tcgtttatac tcttcccata gtgaatctag attttctttt gtatattctt tgatttcgtt
    59821 tagtgcaggt aattcgtaaa ctctttttcc ttcgataaag atatcttgta aaactgggcg
    59881 agctgtaaag tctcgaacag ttttattgat aaacgtatgc actggatgga acatgaagat
    59941 agcttcttct tctcgagggt cttcatccca taatgtcacg tagtctcctt cagatttccc
    60001 atcaaaattt cgagtgatgc gccacacttg ttttttccct ggagtagtta ctttttctgc
    60061 attgcttgat aacttgatcg tatccatcat ttttccttca tcatcttcga tcgatactag
    60121 cttgaatact gcaccaaggg ctggctgatc ataggctgtg atcaattttg tcccaacacc
    60181 ccatacatca attttagctt tttgcatctt taaattcaaa atcgttgctt catccaagtc
    60241 attcgaagca tagatttttg cttccgtaaa tccggctgca tctaattgtt cccgaacacg
    60301 cttagatata taggccatat ctccactgtc gatgcgtacg ccttggaagt tgattttgtc
    60361 acctaattct ttcgccacgc gaatcgcact tggcacacct gatttcaacg tatcataagt
    60421 gtcgactaag aacacgcagt ctttatgggt tttagcgtag gccataaatg cttcataatc
    60481 atttccataa gattggacta acgaatgagc atgggtcccg ctagctggta tcccaaatat
    60541 cttcccagca cgtacattgc ttgttgcatc tgctccgccg atatatgccg ctctagttcc
    60601 ccagactgct gcatccagtt cttgtgcccg tctagttcca aattccaata gtggatcttc
    60661 tccgatgaca gatttgatac gagctgcttt tgtcgcgatc aacgtttgga aattgaccat
    60721 attcaacagt gctgtttcta ctaattggca gtgcgctaaa ggcccttcca cttggattaa
    60781 tggttcattt gcaaaaacta gttctccttc acgagcagaa cgaactgttg ctttaaattc
    60841 aaaattttgt aaatactcca aaaaaccttc aggatagact tctaatccac gcaagtaagc
    60901 aatatcggaa tcattgaacg tcagattctc taaataattg actaaccgtt ccaatcctgc
    60961 aaaaaccgcg tatccgtggt taaaaggcat ttctcgaaag taacattcaa aaacagcatg
    61021 taaatcagct cgacctaatt cccagtatgt ctgcatcata ttgatttgat atagatccgt
    61081 atgcagcgtc aaactgtcgt ctgggtaagt attattcatc ttgtattact cctcttggca
    61141 agttttcatt tcctacccat tataacaaaa aaaattaata ggaaaagaaa tcttccattt
    61201 tttctgaaaa agcacatgtt ttacggatat ttcttgctaa aaatgaactc catctgctaa
    61261 aactatcctt tcttattggt atttaaccta aacgagaaag aatacttatt ttattcaatg
    61321 tatccgagac acgaagaaat tagcgttttc tatttttctt acttgataaa ataagtagat
    61381 tttcctacta caatcgtagc cgttaagata ccgatgattg aacaaatata accaaatgtc
    61441 tctacaacat aatcaatggc aaaagttttt gaagcaataa tacgtctttc cttttttgct
    61501 tcttatcccc aaagaaacgg atataactta ttatgtattg aatttttttg gaaaggcgaa
    61561 ttatgacaag atataccttg cgttgaaaaa actcgcggaa aaaatatcac acgtttttaa
    61621 aaagatacaa agtaagaaag cagctgtcaa tagaatggaa acaaaaatgg cgagacatca
    61681 atcagtctcg ccttgttttt tattgtatac attagatatg gagcaggtta ccataaagat
    61741 gattattagt cgttattaaa tagaatcctt cgtatttttt tgttctatca ctacaatatc
    61801 tttatttgga cgtttgaatt gtattccggc acgttctagc tcctgtttca ctcctacatg
    61861 gactttgaca tcttctcgtg tcatttttaa aacgtgatga atcgcatagt cgatttcttg
    61921 ccttgtgatt tttttcttcg tattgatcat cacgacttgc tttttatcat atgtgtctac
    61981 caatagcagt tgtgttcgat ctaacgaaaa taatttgtaa taattaatag ccgtattccc
    62041 aaaaaagaat tccactactt taggataaaa tgtcttaata tttaaattac tattcacagg
    62101 tgtttcgatt agcttcatct cattcctctt ttctatatag tcgatttaga tccaatctta
    62161 agttatgtta ccatctttcc tagcattaag gaatcggtta caattgaacc tttaaagaca
    62221 aaaggattta ccttttatca cttaatagta taacataatt tcgtgagaaa aaaatacaat
    62281 tttttcttga ccatctcgtt acgtaaagga ttatgcttac atttgtcagg aggaaaaata
    62341 atggagtaca caataaagaa aatgtcagag atatcaggag tcagtccgag aaccttgcgc
    62401 ttttatgatg agattggact gctaaaacca gctaggatca attcttcagg ttatcggatt
    62461 tatggcaaaa aagaagtcga tcgtctgcaa cacatcttat tttatcgaac aatggcattc
    62521 aagttggatg atatccaaga ggtcttagac aatccatctt ttgaccacca gaaagcttta
    62581 atcaagcatc agcaaatgtt gctggaaaaa cgggcacaaa tcgataccct cttgacaact
    62641 gtccaacaga cacttgatat gtacgaagga ggaagaaaaa tgagtgacaa agaaaaattt
    62701 gaagggttta aacaacaaaa gttgaaagaa aatgaagaat cctatggaca agagattcga
    62761 caaaaatacg gaaaaaaaaa ggttacagca tccaatgaaa aatggatgaa tatggataaa
    62821 gaaacgtatg aagaaatgca aactgttgaa aagcagatgt tatttgatct cactctttac
    62881 ttaaaagaac cagaagatga aagcttagca gaccgtatct tccaagctca taagaagtgg
    62941 ttctcttaca gctggcctga atatcagcca aaagcgcata aaggactagg aatgatgtac
    63001 gaagccgatg aacggttcac tgcatattat gacgagcgaa gtggtcatgg tgcagcaaaa
    63061 gctttaaatg aaattatcca aaaaaaggcg taatctttta catgatccaa caaaaaagta
    63121 cacgtaaaat gacctaataa caaaacagca gacacccaag ttagattttt atgctaactt
    63181 ttggtgtctg ctccattctt tcacaagttt tttcatccta ctttaaatat attcatcgtt
    63241 gaataaacgt ataaggtatt ttcactttat cctttttttc tgtaagaaac aattgaaatg
    63301 ccatttctcc gcaagcttcc agatggtggt cgatggttgg gaaaccaaga agctcgctga
    63361 tcagcaaatt atcgcgtcca atcaccactg gtgtcttatc ttgcagatag ctttgcaaga
    63421 tgcctgctgc aaccatatcc gaatttgtaa agacaccatc aactccaagc tctttaaaaa
    63481 agaagcctgc ttgttttcct ttctctgcat ctatacaatc ccaaaaaaca agtgattcat
    63541 caaaagatgg aaaaagttga tgacatagct gcaaagtgat ttttgagtta taacttagcc
    63601 tgccacttcg ccccaacgtg atgcccaatt gctttatacc ttgctgcttc aaataagtaa
    63661 gaccttctgt aattgattgt tctcgatcaa taaagacaca gcttgcctgt tttcccttga
    63721 tttcttcaca aaaaactaga ggtccatatt tttgatatgc caataaatca tctagtgtat
    63781 tggcacgaga cgtaatgatc aatccatcga aagctttagc tgcaaattct tcaagatacc
    63841 ttcgctcttt ttctttatga tagcccgtcg gtaaaagtgt cactttgtaa tcataatcaa
    63901 acgctgcttc aatgatccca ctgatcaact gatcaaaata cggatgattg gtataaggca
    63961 gaatcactcc aatgcttttc gtttttccat aacttaactg tctggcattt gcattaggga
    64021 tataatcgac ttctttcatg accgcaagta tttctttcct tttttcctca tctacatatg
    64081 gatgtccatt gattacacgt gaaatagtag aaactgaata acctgtgagc tttgcgatat
    64141 ctcgaatgtt tgccactgct gcttcgccac ctatacaaaa agattttctt gtaaatagtc
    64201 taccacagct ggaccgcatt caaaaaactg atacattttt ccttcatgcg aaaaactgat
    64261 ccgctgcccg ccccaatata tatcttttgt caaattttcg atttcattca ttggtatttc
    64321 ttttactata ttcctattca acccttgaaa actgtacaac gttaatacgg atcccttgaa
    64381 ctcgacaaac gcataaaaat aattgttcgt tgtgccatct gttatctcta cataagtatt
    64441 cattgcaagc cctccttttg atactttgag tatagtgtat gaaacgcgtc tcatagcaag
    64501 gagtttgttt tgccaaagaa aagttttatt cctctttcat tattaccaaa gtctcttatt
    64561 ttaaattgaa tacattataa tgatactgta aatatatctt tattattagt gaat
//
LOCUS       DADVXV010000005        62166 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.005, whole genome shotgun sequence.
ACCESSION   DADVXV010000005 DADVXV010000000
VERSION     DADVXV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 62166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62166
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.005"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            501..1337
                     /locus_tag="KB969_000273"
     CDS             501..1337
                     /locus_tag="KB969_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBB6868289.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            1401..1832
                     /locus_tag="KB969_000274"
     CDS             1401..1832
                     /locus_tag="KB969_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868290.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(1894..3216)
                     /locus_tag="KB969_000275"
     CDS             complement(1894..3216)
                     /locus_tag="KB969_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBB6868291.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3370..5010)
                     /locus_tag="KB969_000276"
     CDS             complement(3370..5010)
                     /locus_tag="KB969_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBB6868292.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5343..5813
                     /locus_tag="KB969_000277"
     CDS             5343..5813
                     /locus_tag="KB969_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBB6868293.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            6035..7138
                     /locus_tag="KB969_000278"
     CDS             6035..7138
                     /locus_tag="KB969_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6868294.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            7422..8102
                     /locus_tag="KB969_000279"
     CDS             7422..8102
                     /locus_tag="KB969_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6868295.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            8192..9226
                     /locus_tag="KB969_000280"
     CDS             8192..9226
                     /locus_tag="KB969_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6868296.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            9240..9575
                     /locus_tag="KB969_000281"
     CDS             9240..9575
                     /locus_tag="KB969_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868297.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            9559..12039
                     /locus_tag="KB969_000282"
     CDS             9559..12039
                     /locus_tag="KB969_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868298.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            12095..13654
                     /locus_tag="KB969_000283"
     CDS             12095..13654
                     /locus_tag="KB969_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6868299.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            13651..15015
                     /locus_tag="KB969_000284"
     CDS             13651..15015
                     /locus_tag="KB969_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6868300.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            15186..16256
                     /locus_tag="KB969_000285"
     CDS             15186..16256
                     /locus_tag="KB969_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868301.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            16271..16939
                     /locus_tag="KB969_000286"
     CDS             16271..16939
                     /locus_tag="KB969_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868302.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            16959..17537
                     /locus_tag="KB969_000287"
     CDS             16959..17537
                     /locus_tag="KB969_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6868303.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            17938..18849
                     /locus_tag="KB969_000288"
     CDS             17938..18849
                     /locus_tag="KB969_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6868304.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(18937..19854)
                     /locus_tag="KB969_000289"
     CDS             complement(18937..19854)
                     /locus_tag="KB969_000289"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBB6868305.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            20056..20493
                     /gene="zapA"
                     /locus_tag="KB969_000290"
     CDS             20056..20493
                     /gene="zapA"
                     /locus_tag="KB969_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBB6868306.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            20552..21100
                     /locus_tag="KB969_000291"
     CDS             20552..21100
                     /locus_tag="KB969_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBB6868307.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            21215..23575
                     /locus_tag="KB969_000292"
     CDS             21215..23575
                     /locus_tag="KB969_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBB6868308.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            23662..23976
                     /gene="trxA"
                     /locus_tag="KB969_000293"
     CDS             23662..23976
                     /gene="trxA"
                     /locus_tag="KB969_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBB6868309.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            24158..25936
                     /gene="uvrC"
                     /locus_tag="KB969_000294"
     CDS             24158..25936
                     /gene="uvrC"
                     /locus_tag="KB969_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBB6868310.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            26081..26980
                     /locus_tag="KB969_000295"
     CDS             26081..26980
                     /locus_tag="KB969_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868311.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            26973..28235
                     /locus_tag="KB969_000296"
     CDS             26973..28235
                     /locus_tag="KB969_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868312.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            28396..30294
                     /locus_tag="KB969_000297"
     CDS             28396..30294
                     /locus_tag="KB969_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBB6868313.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(30624..31343)
                     /locus_tag="KB969_000298"
     CDS             complement(30624..31343)
                     /locus_tag="KB969_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBB6868314.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            31680..32012
                     /locus_tag="KB969_000299"
     CDS             31680..32012
                     /locus_tag="KB969_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868315.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            31999..34002
                     /locus_tag="KB969_000300"
     CDS             31999..34002
                     /locus_tag="KB969_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBB6868316.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            34021..34491
                     /locus_tag="KB969_000301"
     CDS             34021..34491
                     /locus_tag="KB969_000301"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBB6868317.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            34512..35096
                     /locus_tag="KB969_000302"
     CDS             34512..35096
                     /locus_tag="KB969_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBB6868318.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            35111..36097
                     /locus_tag="KB969_000303"
     CDS             35111..36097
                     /locus_tag="KB969_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBB6868319.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            36087..36398
                     /locus_tag="KB969_000304"
     CDS             36087..36398
                     /locus_tag="KB969_000304"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBB6868320.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            36420..38201
                     /locus_tag="KB969_000305"
     CDS             36420..38201
                     /locus_tag="KB969_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBB6868321.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            38194..39570
                     /locus_tag="KB969_000306"
     CDS             38194..39570
                     /locus_tag="KB969_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBB6868322.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            39577..40212
                     /locus_tag="KB969_000307"
     CDS             39577..40212
                     /locus_tag="KB969_000307"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBB6868323.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            40242..41597
                     /locus_tag="KB969_000308"
     CDS             40242..41597
                     /locus_tag="KB969_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBB6868324.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(41789..43183)
                     /locus_tag="KB969_000309"
     CDS             complement(41789..43183)
                     /locus_tag="KB969_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBB6868325.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            43275..44246
                     /locus_tag="KB969_000310"
     CDS             43275..44246
                     /locus_tag="KB969_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBB6868326.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            44243..45025
                     /locus_tag="KB969_000311"
     CDS             44243..45025
                     /locus_tag="KB969_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBB6868327.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(45194..45565)
                     /locus_tag="KB969_000312"
     CDS             complement(45194..45565)
                     /locus_tag="KB969_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6868328.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            45699..46142
                     /locus_tag="KB969_000313"
     CDS             45699..46142
                     /locus_tag="KB969_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBB6868329.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(46185..46994)
                     /gene="yidA"
                     /locus_tag="KB969_000314"
     CDS             complement(46185..46994)
                     /gene="yidA"
                     /locus_tag="KB969_000314"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBB6868330.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNNEHGVAEAIKKYVL"
     gene            complement(47013..48380)
                     /locus_tag="KB969_000315"
     CDS             complement(47013..48380)
                     /locus_tag="KB969_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6868331.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(48364..49194)
                     /locus_tag="KB969_000316"
     CDS             complement(48364..49194)
                     /locus_tag="KB969_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBB6868332.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            49357..49794
                     /locus_tag="KB969_000317"
     CDS             49357..49794
                     /locus_tag="KB969_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBB6868333.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            49870..50490
                     /locus_tag="KB969_000318"
     CDS             49870..50490
                     /locus_tag="KB969_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBB6868334.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            50679..51185
                     /locus_tag="KB969_000319"
     CDS             50679..51185
                     /locus_tag="KB969_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBB6868335.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            51202..52101
                     /locus_tag="KB969_000320"
     CDS             51202..52101
                     /locus_tag="KB969_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBB6868336.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            52188..53072
                     /locus_tag="KB969_000321"
     CDS             52188..53072
                     /locus_tag="KB969_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6868337.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(53264..53335)
                     /locus_tag="KB969_000322"
     tRNA            complement(53264..53335)
                     /locus_tag="KB969_000322"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53300..53302),aa:Arg,seq:ccg)
     gene            53395..54729
                     /gene="rpoN"
                     /locus_tag="KB969_000323"
     CDS             53395..54729
                     /gene="rpoN"
                     /locus_tag="KB969_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBB6868338.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            54878..55969
                     /locus_tag="KB969_000324"
     CDS             54878..55969
                     /locus_tag="KB969_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBB6868339.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            56010..57011
                     /gene="gap"
                     /locus_tag="KB969_000325"
     CDS             56010..57011
                     /gene="gap"
                     /locus_tag="KB969_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6868340.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            57121..58311
                     /locus_tag="KB969_000326"
     CDS             57121..58311
                     /locus_tag="KB969_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBB6868341.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            58415..59170
                     /locus_tag="KB969_000327"
     CDS             58415..59170
                     /locus_tag="KB969_000327"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBB6868342.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            59286..60584
                     /gene="eno"
                     /locus_tag="KB969_000328"
     CDS             59286..60584
                     /gene="eno"
                     /locus_tag="KB969_000328"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBB6868343.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            60983..62122
                     /locus_tag="KB969_000329"
     CDS             60983..62122
                     /locus_tag="KB969_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBB6868344.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        20530 a        10893 c        13093 g        17650 t
ORIGIN      
        1 tccaaataaa cgatgttcaa tcagctgccc ctcggcattc gctcgaaaaa cggcgaaata
       61 tgaagaacta ttttgccatt tgtttctcta ataatcaggt caaaacgttg acttcacagt
      121 ctcttcctta aacggtgttc tcctgccaac tcctcggtca caagtcacaa tattcaacaa
      181 acatgagaag ctgttttttg aaattgttcc ttgtgactcg gagctgaacg gcaggctcac
      241 gacctctttc ttaaacggtg ttcaaaagct tgcatctgcg gtaataagtt caaccaaacg
      301 aaaattatga ggagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt
      361 tcacaacctc ttttcgttta gcactaaatt tccttaaaaa gtagaaaagc tttcgaagcc
      421 tcgtttgttt cttttactgt ataataaaag aaaagagtaa caatcgctaa aagatataaa
      481 caagagaaag gaaatacaag atgattggtc tgatttattt tgtggtgatc gttctggcga
      541 acacagttgg cgctatttcc gggatgggtg gaggcgtgtt gatcaaaccg attcttgatc
      601 ttatcggcgc ccattctgtt gcagggattt ctttttactc aacagttgcg gtattcacga
      661 tgtccattgt ttcgactgtg cgacaagtat caagcgggaa atcactgaat tggcagattg
      721 tcggttgggt atctagtgga gctgttgttg gaggagtagt cggcaacatt gtattcgaag
      781 tttttttaca gttatttgaa aacgagaagc atgtgcagct gatccaaatt tttttgacgg
      841 tattgacctt ggtttttgcg ttcttctaca ccaagcatca tcagccaaaa tttcatttga
      901 cgtcatggac ttggtacctt atatgtgggg gggttctggg ctttttagct agttttttag
      961 gtattggtgg tggaccagtc aatgtttctt tgttgatgct gatgtttgca ttgccaataa
     1021 aagaagcaac actatattct ctatctacga ttttcttttc tcaactggca aaattggtaa
     1081 cgattgcttt aacaagtagc tttatgcgct ttgatttatc tatgttgttt tatgttatcc
     1141 ccgctgctgt tattggaggt ttgtggggag caagatttag cagggttttg tctccaaaaa
     1201 aagtgacctt tatttttcaa gtaattgtcc tcgtggttct tttgatcaat ctttacaatg
     1261 ctttcgtcat cttacaaaca ttaggagaat ctagactaac gcaagtcaaa atcactgaaa
     1321 catattgttc taaatgaaaa aaggagtata ctgtgataaa aaaattcatt taaaaaaata
     1381 aaaattggct ggtgatttgg atgttgcggg aaatgcgttt aggagatgca gaagcactac
     1441 gagaaatcaa tgcggaacaa ttaggatatg atgtaccatt aaccgttacg gtgagacaaa
     1501 tgaagaaact gttgaaggag ccagaaaaaa attttttctt ggtctatgaa gatcctactt
     1561 ctaaaaaagc agctggctat gtacaagcgg agtcctatga atcgattttc agcgatccga
     1621 tgttcaatat tatggcactt gctgtgtcta aacatgctga aaaaagagga atcggaaagg
     1681 ccttgatgac tggcgtagaa gaagcgaaaa gacgaggaat atcagcaata agacttaatt
     1741 ctgcagaata cagagtagaa gcacaccgat tttatgaacg catcggttat cattccgata
     1801 aaatgcaaaa aagatttttg aaaatcctgt aaatttttat caaaaaatac ctggtcatca
     1861 agccgatact tgatgatcag gtattttttt tgactaagaa agtaattgca tcaagaaacc
     1921 tgagatgatc aaaacgatgg caccaccaag ccgattgccc atttgagcaa aagcaataag
     1981 ttccatccga ttagctgcag ataagacagc tacatttcct gtaccaccca tcgagttgtt
     2041 gcataagcca gcagtaatag ttgattcgat tggatataaa ccaaacaaac gaccgacaaa
     2101 tcctgaaact actgaaatcg cgataacact tgtcaaacat aagacaacaa attgccatgt
     2161 caaagcagaa gccaatacat ttagattcaa taacgcaata ccgataccgg caagaacagc
     2221 tgctgtcaag tttttgacaa tcaagttgtt gaacatgata gctgcatctt cgtaatattc
     2281 tggtaatagg tttgcgattt tacagataac aacgataatg atcatgaatg cgtaagcatg
     2341 gactttagga acaaaatagt tacagatttg tcctaagatg aagaaagtca atgataccat
     2401 caaaccgaca cctaattgtg gaatggaagg ttttacattt ctaggttttc catcgccaag
     2461 gtcgcctttt tccattaatt taccattacc gttgaatttt ggcattgatt gtcccgcacg
     2521 agcaactaac gctgcaccaa tgatagctag gacatttgtc attgctgtcg caggaatcag
     2581 gcgggaaatg atagaagaag cgtccgtacc taaaacattt gcataaatcg ttgataaagg
     2641 tacagctccg gctccaacac caccagccat tgcgggcaat gagatatata aaacggaatt
     2701 tgcaaaacca tttccgataa gcatacctac gagtcctacg gcaaaaaagg agacgaccat
     2761 tgaaataagt gcaacgggaa taaaacgaac agaagctttc atcaatagat tacggttcat
     2821 accaaggatg ctaccagtaa tcaaggcagc aatataaaag tctaaaaagc ccatattgct
     2881 gacaaagttt tctgtggatt ttactacata ctcaggtaag atcccaaatg tagcaatcgc
     2941 ggcagaggca aagatcgcaa aaacggagcc accacctaaa taacttttga cgatagggat
     3001 ttttgttccg ataaaatgaa ataaattacc gaaaatgacc aaaacagcga ttgggccaat
     3061 catattcgtc ggtaattttc ctaaagccat tgcaatgatc aggacaagga ccatgatcaa
     3121 ataaaggggc aaacttacgc cggtaatttt tgttgaccaa aacccttctt ttttcttttc
     3181 ctcaactgca gttgcggttg ttgttttttg tgccattttt acagatcctt tcttattctg
     3241 tatcgtatga aaaaagccaa agagaagcgg caaaagagca gtagttggct ggctgctgtt
     3301 ttgccgcagt cgcttttttc tttttagacg tcatacaaag tttctgtatg ttcttttact
     3361 ataacaatct taatcttcta aagatttata ttcaggaacc catttagcag attcaacagc
     3421 ttctttgata tccgtgattt cttcacgatt caatttttgt gcaacaactg attttgcgac
     3481 agtttcagca atcgtttgag agaattcagt gatttttgct actggaggca agatagctgc
     3541 tcctggtttt gttacatcaa cgattccgcc taatgctcga ctagcttgag aaatgatttc
     3601 agcatttact cgtgtagctg ttgaagcaat caaaccaagc cctaaacctg ggtacatcaa
     3661 cgcattattt gcttgaccga tttggtaagt tacaccgtta tattccacat cagcagcagg
     3721 gatacctgtt ccaactaaag cttttccgtc cgtccattca atcaaatctt ttgcttttgc
     3781 ttctgccaat tttgttggat tagacaaagg catgatgatt ggacgtgggg tatgagccgc
     3841 catttctttc acgatttctt cagtgaatgc tccaggttgg gtagaagtac cgatcatgat
     3901 cgttggatgg attgctttta caactgcttc taagtttgtc aattcatcag cattagtgaa
     3961 ttctgagcgt ttacgagcga atgggatttg accaggagtc aatccttttg tatcttcaaa
     4021 caataaaccc tgtttatcta cttgatagaa atgttggcgt gcttcttctt caggtacacc
     4081 ttgacggatc atttcatcta aaaggatgtt tgcgatacct acaccagcag taccagcacc
     4141 aaatgtcaag atcgtttgat ctttcaattg ctcacctgat atattcaatc cacctaatac
     4201 accagctagt acaacgattc ctgtgccttg gatatcatca ttgaaagtag tgattttatc
     4261 ttcgtatttt tctaagatcg ttgcagcatt tcctcgtcca aaatcttccc aatgtaataa
     4321 caattctggg aataattcag tagctgattg aacgaattga tcaatgaatt cgtagtaagt
     4381 ttcgccttct acacgagcat gacgattccc taagtataat ggattattca ataattcttc
     4441 gttattagta ccagcgtcga ttgatacagg caagacttgt gcaggattga taccagccgc
     4501 agcagtgtag accatcaatt taccgatagc gatgtcaaca ccgttcacac cccagtcacc
     4561 catacctaag attccttctg catctgtcac aacgatcaaa cgaatgtcgc gtccatctgc
     4621 tgcgtttttc aaacttgctt tgatattttc tggttcgtcg attgaaagaa atgcagcatc
     4681 ttgtggtttc aagaaaattt cgttgtattg ttcgattgaa tccgcaacga caggatcata
     4741 aacgacaggc atgaattcaa ctaaatgttc gcccatcaat ttataaaaca atgtccggtt
     4801 cgtattgaat agattcatta agaagatacg tttttccaaa tcggtctgtt tgcttaagta
     4861 ttgaccgtaa gcttggacag attgttgttc caatgtttgg acagtacttg gaagcatacc
     4921 agtgattccg tattttgccc gttcttcttt tgtaaaagct gttcctttat ttagaaaagg
     4981 attatttaat aagtttagcc ctgtaagcat gaatgattcc tcctaagttt taatacaaac
     5041 gaagtatagg agtcagatga ggatatagtc aaaaagagca ggtataataa attttattta
     5101 tatgagtaat agagtcaaaa gaaatcaaaa tagcggtatt tgttcttttt atatcaacaa
     5161 tccttgcttg attactatgc gtatctctta tatgctaaag aaagaaaagt agaagaataa
     5221 aggatatgtt agatagataa atagaatctc tgaagaataa atcacgtgat cgtgacgata
     5281 aaatacactt acgtcaggtg ataaaaaata cataagtaga aaactaagag gaggaacaga
     5341 aaatgaaaga agttcaattg atcagaaaaa gcgaactatc agaaggtggt tgcaatgcat
     5401 gcggcgtagt agaagcaaca agctatacat taaagcttgg tgccaacaaa gcgataatct
     5461 ctgagttgac agtaggcggt cttgtggaca gtctggcgct tgctgaaggt tttattggag
     5521 aagatattta tgagatgttt tcagaaatcc gtcagttaaa aaaaggggaa aactgcatag
     5581 aggttcatca tgagagcccg aatgtgagat tcaaacgtgg tgataatgag atgatcttca
     5641 ataatcatgt gtccgatcac accgagctat atggaatcgt gaatcaaata ctaactgagc
     5701 tttttggatt gggaccttat gcgttcaagg aagaaaacgg taatccaaaa ttaaacgaag
     5761 aatggcaaga aacgattgaa atacaaagaa acaacccgca cttatttcaa taggcatcca
     5821 cagtatttcg taaaagggac tttgacacga cttttgtcaa agtcccatcg ttttttatct
     5881 atttgtgttc taaacatttc tttcagagta gtaacaactg gaatgactga aatgtaaaca
     5941 gattatttgc ctgtatcaat acggaagagt aatataaagt gtgtaaacgc tatcatatta
     6001 ttcattcaat tttttataga gggaaggcat tgaaatggaa aaaacgtatc aagcaggtac
     6061 aaatgaagga atagtggatt ttatcaatat ggaagattta gaaatagccg cttcacaagt
     6121 gattccagct ggtggttatg gttacatcag cagtggtgct ggcgacttat ttacttatca
     6181 agaaaatgaa cgggcattca atcatcagct gattattcct catgtattaa aagatgtaga
     6241 attacccgat acaactacac attttgacaa agaaacgctg actgcaccaa tcatcatggc
     6301 accagttgct gctcatggct tagctcatgt gaaggcggag aaagcttctg caaaaggtgt
     6361 agcagatttt gggacgatct atacagcaag ttcttacgct tcttgtacat tagaagagat
     6421 aagagaagca ggcggggaga aagcaccgca atggtttcaa ttttatatga gcaaagatga
     6481 tgggatcaat ttggatattc ttgaagtggc caagcgtaat ggagcaaaag caatcgtatt
     6541 gacagcggat gcaacagttg gcggaaaccg tgaaacagac cgcagaaatg ggtttacctt
     6601 cccactgcca atgccgatcg ttcaggctta tcaatcagga gtaggccaaa cgatggatgc
     6661 tgtgtacaaa tcttccaaac agaagcttag tccaaaagat gtagaattta ttgctgctca
     6721 ttctgatttg ccagtctatg tgaaaggtgt ccagtcagaa gaagatgtct atcgttcatt
     6781 agaatctggt gctggcggaa tctgggtatc taatcatggt ggccgtcaac tagatggtgg
     6841 tccagcagcg tttgattcgt tgcaatatgt ggcagaagca gtagataaac gtgtaccaat
     6901 cgtgtttgac agcggtgtac gacgcggaca gcatgttttc aaagcaatcg catcaggtgc
     6961 agatcttgtt gctattggca gacccgttat ttatggattg tctttaggag gaagtacagg
     7021 agtccatcaa gtgtttgatt tctttaaaac agaattggaa atggtcatgc aattagctgg
     7081 aacacaaaca gtagaagata tcaaaaaaat aaaattgcgt gagaatcgtt ttatttaaga
     7141 aacaaatgac gaaaaaaata ggagtgcggc agatgatgcc gtactcctat ttttatagtt
     7201 caaggatgtc actaatagaa taatttgaaa cgaaaaaata aaattgaaat attttttcat
     7261 acttaataaa aaaggaagaa tattcatgta aacgatttta ttgttttttt ctcttttata
     7321 caaaaagggt cataatttca agtaagcgga tgaattcatg aggatttttt gcatactgtc
     7381 tctactatac ttaggtcact aagaaaaagg agtgatttat tatgaaaaag aacatgattg
     7441 ggacattatt actttcaaca cttcttctag gcggcttggc aacaccagct tttgctgagg
     7501 gtcaagcgac ttcaaaagga gatattacct ttactgaacc aacaaatacc gtggagcctc
     7561 ttaaccctac tgatccttca aaaccagtag agccagcaga tccggaaaat ccagcaactg
     7621 gccagacagg tcctttaaca ctggatgtag ttcccgaatt gccatttggt acacacgaga
     7681 ttgaaagcgg aacaaaaacg tatcaagtag acgcttcaaa aaacgataca ccttatctcc
     7741 aagtatcaga tcgtcgaggt gtaggtgcag atggccaagc acaagggtgg aacgtgacag
     7801 tttcggtttc agattttgta aacggttcac aagttttgca aggcgctgaa ttagattttg
     7861 gaacatccac tgttaaaagt acgtcagata acgaatccac tggaccaact agtcaaactg
     7921 taactgggtt gagtaaagca agtgcagcga caccaatatt tacagcagca aaagatcaag
     7981 gtctgggaac atggctttct gtttatgatc cagcaaatat cacactgaaa gtgccgaaag
     8041 cagcagctgg aacattcacg gctgatttga cttggaacct cgtggctggc ccagtagcat
     8101 agagtatgaa ataaattcaa caaactgcgg tgaaaatact ataggtgaag gattttttac
     8161 cgcagttttt gttgaaagga tgtggtggac aatgaatcaa agtaaacgac tgtttgtttc
     8221 gtttttttct attttaagtc tatttttcat ttttccgtca atcagccaag caaaggattc
     8281 agcaggagac tttggaatca aaccggtatt tccagagaac caaatagata aagcaatcgg
     8341 ttattttgat ttattagtgg caccggaaca aaatcagaca ctagaagtaa ttatcagcaa
     8401 ttcttcagat gaagaacgaa catttgaggt ctctgtcaat ccggcggtaa cgagtgatgg
     8461 tggaacgatc gattatagtc aaaaaaaccc aacgttagat gagacattgc cgtttgatgt
     8521 ccgtgacgtt ttgctcattg cgaaaaagga aatcaatgta tcagcacatg cagaaacaac
     8581 tgtacctata gaagtgaaaa tcccagcaaa aagctttaag ggacgtgtat tagcgggtat
     8641 tcatgtttca cctaaagaag aagctgaaac agaaaatgct acagaaggag cacaaatcaa
     8701 aaatcgtatt gcttataatc tcgcagtcgt tttacaagaa agtcaagaga cgatagaacc
     8761 ggatctgaaa cttttatcag gagatttgga cgaggtcaac gcaaagccaa ctgttcagct
     8821 tcgtttccaa aatcctcagc ctaggattat cagcaatttg atatttacga gcaagatctt
     8881 ttatgaaaat cagctttata ttgaaaatac gtctaatgca tttttagttg caccaaattc
     8941 gaattttcac ttgaatcttg atttagctgg tgataaagca aaagccggcg attaccgcgc
     9001 agaaatcata gcaaaatcag gcgacagtaa tgaatggcga tttacacaaa actttacgat
     9061 caaaaaagaa aaagcacaaa aagtaaatga aaattccgtt tttgcagtac aagaacaatc
     9121 tttcccatgg ctttatgcag gattggttgc tgcagttcta gtgttatggt tgattttgct
     9181 gtttttgtgg gtccacaaga aaaagaaaaa aggagaaaca acatgatgag gtgatttcgt
     9241 tgaaaacatc gatcttattg ggagggatta ttgcaagttt gctgttcttc agctggcaag
     9301 agccagtcca agcagatacc aaaagttcag gtacgattac attttatgat ctaagtccaa
     9361 ttccgcatcc aagtggttca gtcaatggcg catcaaaaca gcagacacag ctaccgattt
     9421 ataaagaatc taatcaacat ggcgtattcc cggagacgaa tgaacaaaag atccgttttc
     9481 tttatttgat cattggtata gaattatggc ttcttgcgtg gttgttgtta tggagaagaa
     9541 aggaaaagga ggatgaacat gttgctacaa aataaatttt cattttttcg ctccttcttt
     9601 tttacttcgc tttttgtttt aagtatattt atcttttcac cttcggcaga agctgttgga
     9661 gcaacgcctc ctgccatttc ttatgatcca tacacgtatg aaaatatcgt acctccaaat
     9721 ggtggacgta gtgcagtcaa tggcgggaag cttgtccaac taactggggc taaccaattg
     9781 cctaaattga ctgctactta tttgaacgat ggttcaaatg atccttggaa aggtggcacg
     9841 gtccgttttc attgggaaag ccatgtgaaa ctaacaaatg tacttgattt ggtgaatatc
     9901 actgcacaag gatttgcatt tgtggcgatc atcaatttgc cggaacatgt atcaagcagt
     9961 gatgtattaa aagcaattga ctggaacaac gcctacttgt atattgccgg tgcccccatc
    10021 aaggttacta gcggaagttt attatcagca ggaagccata ccttgcgttt tgggatgggg
    10081 tcgtgggata caaatactct attgacagat attattgcta ttattacgcg aggcgaattc
    10141 aacgtggacg atatcccgct tcaatttgat gttacagcta atgtcgcgaa gatgacagaa
    10201 aacggagata aatatgatac gagtccaaac aaaattttga ccaagggtaa attacaacct
    10261 tctatgtcta aaaaggccgt tttttctgtt gatttttatg attcgaataa tattatccaa
    10321 gatcgtatgt tcaattcgat tttagctcca gctgcaggta gattttatcc taaattaact
    10381 ggcggaaact tgaatccagg agcatatgca ttttctgcaa gtgcagagat aaatacgtgg
    10441 aatagttaca tctcaccaag tgattcaaca ggaaaatata atacatttgc tgataccaca
    10501 gaatacgtgg atggaaataa ccagaacctt ccaggctcta ccaatagtcg gacattgacg
    10561 atggggctga ctgaaggacg ttttgatcag ttgccattta gtcgctttga tcgcgtagtc
    10621 aactatttta caggaaaaaa cgttacacaa ggagcaatac tgactcatac tccagcaagc
    10681 acaagtggat tgaatcagac agccaatatc gtgtacagtg ggaaagatgc gcaaggcgga
    10741 ttgctttctc ctgttgcttt aaaggtattg gagcagtaca agctagacgg aacggtttta
    10801 ccaacaaact taacagccga tagtcagtgg ggaaagctcc tttcttctgc atcgtaccaa
    10861 gtcacggcca attggtcagc aactgaacta aaaaagggtt cgatccatta caggctttat
    10921 tcgaaaggaa cccaaaaatt agcgacagga tggacagatc aacttttcca aacgatccaa
    10981 tcaaataacg ggggtgtaaa tacagctact tctacactac ctgcattggc ttcagggcaa
    11041 tattattttg attatcgctt ggtggacgat gtacttacta acatgtatcc gtcttttgcg
    11101 tacaaatggc agtctgaaca agctggaatc accactcttc ctcaaataac agtggctaat
    11161 tttccatctg tgagtgcaga tagtcagcta aaaaacctta gcagacaacc tgagacagga
    11221 gatcccctgt ctgctctatc aggagatacg attcaagaaa atgtgacatt cacgttaaca
    11281 aaatctgggg atgcgataac cgacaaaaaa atcacgatct cacttcctga aaatactact
    11341 tatatcaatg gttccttaaa attaaatggt acaactatcg cagataccgg cattcaacaa
    11401 ggagtttctg tcccagcaga tctattgagc aaaataggag ataccattca tcttacttac
    11461 aactatcaat taaatactgt agatacttct ttacaatccg tcagcatact gacaaaggca
    11521 gctgtacttt ccagcaatat tacattagca gatggtgcta agcttcctaa cccagttgtc
    11581 caaacatctg ctaaaacaat tcttgtcccc aaacaagaat taacattagt taatgtacca
    11641 gatgatttta catttggtaa cgatctcccc aaaccgttga agacaagtta ttatgaatca
    11701 aaaggcgatt tttcttttga tgtgcgggat actcggcttc caagcacgtc tccttggcaa
    11761 ctgacaggta cattgacttc tttatttaag aatgatcaag gtcaagaatt aagcggaaca
    11821 aaattatact tcaatcattc tggatcaaag caattgattc agcaaggtca aaacacgttg
    11881 atttatgaga gtgatggaac agctaaagga gaggttctcg ttgactttcc cgataccgat
    11941 ggtttactct tagaggtaaa tagcagtacg aatgctcaac ctggcgcaac gtatcaaggc
    12001 atggtcacat ggaaactgac agctgggcca accagctaag tgattagaat ttgtatggat
    12061 ctgtgataac tgtcacagat cctctttttc aaggatgaga aggaaacttc tgctgttaaa
    12121 atcagaaatg cttgaaggag tggacttgga acttttcagt ttgcttgaaa aaaatgaaca
    12181 acggcaaatc aaacttttcc aacttttatt agaggaaaaa ggagaggttt ccgttaataa
    12241 cgtacttacc cgcttatcag ttgatcgggc taccttgaaa gaagatctgt tttatttaca
    12301 agctaacttg gaaaatatca aacaattgga aattgttatc caagaaggga atattttatt
    12361 aatcagacat ggaaatatag cagcagtcga tgtttattat cattgttact tgcgctattc
    12421 tacaaaatat cagatacttc tttatctgtt ggaaaatggc tcatttgatc ggcagaaact
    12481 tgtcatggaa cttaatatca gttcggctac tttgtctcgc agagtgaagg aattaaatga
    12541 ttctttaaat gagtttcatc tgaaaataaa aagcgggcgg ctgaccggtc cagaaagtca
    12601 aattcgttat ttttatttcc aattattttg gtttggacgt ccctatcttg aaaacaaaaa
    12661 agaatacagt gatttatcag gaaacacttt tttagatctg ctgcaaaaag agtttagttt
    12721 tgctattaca gaagaaggac gattgaaatt tgaaatatgg ctttccatta tgaagaagcg
    12781 aatgcgctgt acgaaaaaat ccaaaccaga ttatagcaat cttcctgttg gattgtttca
    12841 aacgacacaa tttttattgg acctccatac atttttgacc cgttacttct ttcaatatgc
    12901 ctttccttgg aatcaaaatg aaacgttggt tttttatctt ttcatgatca gtaactttac
    12961 attagataca cataactcgc atgtccagga gtttttgata agcgaaaaat acaaagacga
    13021 cgtagtagct caattgaatc gaacgtttaa acaatcgata gaagaatatt tctcttttta
    13081 tgtttttcca gaagagattt cgcaaaagat tgcgttgaca gtgatgcaaa atcacgctca
    13141 ttttgcctat tttagaggat ggatgaatat ttttggccaa gaaggattaa aacagcggtt
    13201 aactgaagta gaagataaac aattcctggt tttatgtgaa agattggtca gacaaacatt
    13261 tgctattgtt gattttactg aagtagacga ggaaaatgcc cgctttgaat tatttgctcg
    13321 ctatgcatct attttacgga cgctgatcaa gcagttagaa ttacgtctgc aaattgctta
    13381 tgatcttcct tatgaaaggc taatggcgga tatcgtgaaa gaaatcatcc aggaacaatt
    13441 gctgaatacg atcaaatatg atttagtcga atacgagaaa gaaaagcagt atgatatcat
    13501 tttgactagc caattgaaag agtacccgtc acagaagtcc gctaaagttt ttgtattcac
    13561 tagcaacgaa tataattatg atttccccta tttgaaccaa tttttaaaag aatgttattt
    13621 agaaaaattg aatttaagga tgaataaaac atgaaaatcg tgatcattgg tgcttcccat
    13681 gcaggcatca cagctgccct aaatctaaga aaacttcaac cgaaagcaga agttttactg
    13741 atcgatgaag atcataaaga tggactaggc tatgtttcaa atggaatcaa cctttattta
    13801 aaaggaaaga tacgtagttt agctgaagtt gcccataaca tgcggactct tcaagaaagt
    13861 ggggcaaaac tgatcaccga atggagagta actgaacttg atccagacaa acatcagctc
    13921 atcctcgcat ccaaagaagg aaaaaacgag accataacct atgataaatt aatcgtagcg
    13981 acaggttcct ctcctgtcac cttgtataaa caaattgaag ctgaaaatgt ctacacctat
    14041 aaaaatctag tgcaatctaa gcaagtactt gccgctttaa aagaagcaaa agaagtagtg
    14101 atcttcggtg ctggttacat tggattggaa ttagcagatg ctttgagaaa taaaggatac
    14161 attattcatc tagttgatta tatgccgaat gttttatcaa gatatttcga taaggatatg
    14221 atcaacagtt ttcaaaatca gctgcaaact aagcaaataa atttttatcc aaatgaattc
    14281 ttgatcgatt ggaaaaaatc agaagagaaa gtagtatccg tacaacttct gtctcaaaca
    14341 ataaaggcag atatggtcat tttttctgcc caaactcgtc ctaatacgac attgttaaaa
    14401 gaaaaagtgg ctttgtatga ggatgagact gtgatagtca atgaatatct gcagacaagt
    14461 gatccggaca tctatgcgat tggagatatc gtcccagtca gttttgacaa aaataaacgg
    14521 catctctttt tacctttagt tactcgagct gtacatatgg caagagcagt agcgctaact
    14581 ttgagtggtc agccaaccgc ttacgacctc agacaaaaga taacagcagc agtcattata
    14641 gactactttt taggaactgt agggctgaca gaagatgaag cgccattctt ggaacaaaat
    14701 accggttcgt gttcaggaga atttgatcta tttccacaat acgacgaaga aaacaaaaca
    14761 gtaaatgcaa agctgatcta ccatccggat acattagaaa taattggcgg acagctgata
    14821 agccaagaat tcttattatc agatttgaac ctgcttgcgg atatcgtgaa acacaaaact
    14881 acgattccac agctagcagt tgaggatttt ggatttctgt ctgaatacac ctctcgtttt
    14941 cactacctca atgagttagc ttttaaagta ctagctaaga gagcaaatag caatagagta
    15001 gataaaagac tgtgagaaat atcacggtct tttattgtgt ggggatataa taaatattaa
    15061 tcaatcgaga ataaaaaatt catataatga aatagcggaa gaattttttg agcataatat
    15121 tcgccaaaaa tttatcaagt gataaaattg ttgtataaaa tgattatttc aggaggagga
    15181 gttaaatgtt tttagcatta aatgaaatta tgcattcaaa gttacgttat gcgttagttg
    15241 caggggtgat gtttttgatc gcctacctgg tatttttttt gactgggtta gcttatggct
    15301 tagctcaaga taatcgaaca gcagtcgaca agtgggaggc agattcgatt gtgctttcga
    15361 aagatgcaaa ttcaaatcta gggatgtcca tgattactaa gaagatagca gaagaagtcg
    15421 aaggtgggaa agtggcgtat cttgcccaaa cacctggagt cgtgactagt aaagacagta
    15481 cagaagaagg aaaaatcaat gttagcttct tcggtatcga taaaaatcaa ttcatcatgc
    15541 ccaatcttgt tgaaggaaaa gcttttgata acgatgatga ggcagtaggc gatattagtt
    15601 tgaaagaaga atatggtcta gccataggag atacagttaa gttatctggt agtgacaaga
    15661 cgtttaaact aactggcttt acggatcatg ccaaattcaa tgtctcacca gttctctata
    15721 caaccatcaa tgcttaccaa gaaatccgct tcgaaaaaga agatacaagt gaaaatgcac
    15781 ggattaacgc aatagttgtc agaggtaaaa tcagtaattt acctgaagat ttagaacaga
    15841 tcaaaatttc taaattcatc aatgaattac ctggatataa tgcgcaagta ttgacttttg
    15901 gatttatgat cggatttttg atcgttattg cggctattgt gatcgggatt ttcatttatg
    15961 tactgacgat gcaaaagatt aatatctttg gtgtaatgaa agcacaaggg atcacaggag
    16021 gatttattgc gcgttctgta gtggcacaaa cattcatttt atcatttgtt ggtattcttc
    16081 ttggtctatt aggaacagtg ggaacatccc ttgttctacc tgatgcggtt ccattccaaa
    16141 gcaattggct gttttttggc gtcattagct tgttgatgtt agtagtagct gtgttaggcg
    16201 cactattttc tgttcggaca atcgtaaaaa tcgatccgtt gaaggcaatt ggataagaag
    16261 gaggaagaac atgaaagcaa tagaatttaa agaagtagaa aaaagtttcc aagatggcga
    16321 ccaagtagtt aaagcattga aagaaacaac catgagtatc gataaagggg aatttgttgc
    16381 aatcatcggt ccttctggtt caggtaaaag tacttttttg actttggcag gcggattgca
    16441 gacgcctagc agtggctctg tatttatcaa tgatcaagaa ttcagtaatc aaaaagaaag
    16501 cgaacgcgtt aaactacgtt ttaaagaaat tggctttatt ttgcaagctt ccaatctggt
    16561 tccttttctg acagtaaaaa agcagttatt attagtagat aagattaaac atgaacatcg
    16621 tcaaaaagaa gcaaacgaat tatttgagca gcttggcgtg gataagttga tcaacaagta
    16681 tccagaagaa ctatctggtg gagaacggca aagggtcgca atcgctcgtg cattgtacaa
    16741 tgatccgtcc attattctag cagatgaacc aactgctagt ttggattcag aaaaggcacg
    16801 agaagtagtc gatatcttgg caaaagaatc aaaagacaaa aataaagcaa cgatcatggt
    16861 tactcacgat acacggctga ttgacaaatg cgatagaata tttatgatgg aagatggtgt
    16921 attgaaagaa aaagaataac caaaaagcag gtggaaaaat ggtccatcga tacaacaaag
    16981 atacacagca aaaaattttg aaagaagcga ctgacttgtt tatgtccaag ggatatctcg
    17041 gcacttcaac aagagaaatc gcacaaaaag ttgggatcac ccagcccaat ctctatcatt
    17101 atttcggtga taaagaaaaa ctatatacgg cagttttaga aaaccactta aaagatgttg
    17161 gaaaagcttt gagagaaatc gttcaaacaa gcgaaacggg atttcaagta accttgacaa
    17221 aaatggcgca gtttttgatt gagacacatc tggtcgattt gtttctgatg cttcacgatc
    17281 ttgaaagcaa tctttcaaag gaaacaagag atcatctttt ctttctatgg aagaaaaatt
    17341 atcgtgaacc ttttgaagaa atcttttcag caaaccaatc tgtgctaaga aatgggattt
    17401 caaaagaaat cgcagcaagg cattttttct tagtgttagc accttacatc actcggtcga
    17461 aaagacctgt ggaagaaccg ctaaatgtgg cgcaattgat cgatttatat ttgaatggtg
    17521 tattaggaga agcgtaaagc tgttatatag ggagaaaata gttaggtgaa gaagcaagat
    17581 atgacgaaga tcgttatatc ttgcttcttt atataggtag tttttcataa agacaaattt
    17641 gttattctct catgattatc agggtatatt tttatttatt atgtcggtgt tccaggaagt
    17701 gttttaattt aataacgaag aaattaattg tttgtagaat gaaggaaact atttattggg
    17761 tagatgaatc accacgaata gtcaaaagga gatttcagga tatgccaaaa atgaaaaaaa
    17821 tcattttagc agtaatgtta ttttctacgg ttatatcttt tacagcccct tttttgctta
    17881 cttaagctga ttttaagttt tggcccttag tctggatcta cgaggtgaga gtcaagaatg
    17941 aaaaaaataa ttggagcttt tgtatttgca atcattatca ttattatctg ttttcaaata
    18001 gatgtttttg gtcaaaaaaa gatagttgga caaacggtca gcagtacgaa cagtacggtt
    18061 acaaagacaa aggaatcatt tgatgataca gaacaagaga cattaatcaa aatcggaaaa
    18121 aatgaccgta cactatatac agatgactcg ctaactaccc cacttgcaac tataaacggc
    18181 ggagagctgg cggagtttct ttctgaaaca aaaaatgctt atcagatcaa gacaaatgat
    18241 ggctatactg gatatttagc cctcgaagat ggaaccaaag tcacaaagaa tatacaaaca
    18301 aaaccggaag agctatctga tgcagtgatt gtattagatc ctgggcatgg cggaaatgat
    18361 actggggcat taagcaatga tgaacaaaca gaagaaaaag atataacatt aagtacagcc
    18421 ataaaagtaa aaaaggcgct agaggatgct ggagcaacgg tttatttgac ccatactaca
    18481 gatgaattag tacagcttgg agatatatgc gactacagtg aagaaaaaaa ggcagatgtc
    18541 tttatcagtt tacacgcaga ctctacggaa tatgcgaatg aagcaactgg aatcacgaca
    18601 tattattact atggacaaga ggaaacatta gcacagacaa ttgctgactc cttcactgat
    18661 ctgcctctgg attcaagagg aatctccact gggaactatc aagttcttcg agaaaatctt
    18721 caaccttcta ttttaatcga gatgggttat atgaataatg atagtgattt aaaggaatta
    18781 gtaacagaca gttatcagca gcagattgct gcaagtttga cacaagcatt gaccacttat
    18841 tttcagtaat aaataagccc agccaaacaa aaatagctcc tcatattttt cgtttggccg
    18901 ggcttattat cgcagatgca agcttttgaa caccgtttat ttttttagta gcttcaaagc
    18961 tttttctgta tttgcaaagt gaagtttggc atatttttca agcataggca tgccgccttt
    19021 ctccaatagt tttgccgcta cttggtcaga tttcgttcca gctcctgatg gaagggtgat
    19081 tccagcttca gctgatgctt tgtgtaactc ttccaaaaag ctggcacgac tgatgataga
    19141 agcagcagca acagctaaat gatattgttc tcctttagta acgaagtaca gtttttcttg
    19201 taattgattt ttttctaaac gcgcatattt tttaaaattt gcttccggcg taaactgatc
    19261 gatcaaaatc gcttctggtt tttctggctc gatttttttt agcagcaaat ggatcgcttg
    19321 attgtgcaaa gcgactttca tccgaacggc attgtatttt ggttggatct cattgtattt
    19381 ttctggagat aagacaagca gtttataggg gatggttttt tttaagatgt cagcaagctg
    19441 gatgatttgg ctatctttta actcttttga atctctaaca ccaagtttac gtaattctgc
    19501 aagctgatca cgtttcacat aagcagcaca tactgttagc ggaccgaaat agctgccatt
    19561 tccgacctca tcactaccta aaacggataa ttgactgata ttttttggca aagaagaggc
    19621 tgtttttgct ggcttggctt gtttatcctg tgcctccccc catttatcag cttctattgc
    19681 tgcattcgta ccttgaaaca tcacttttcc ggatgtataa gcggtaatgg tcgtcccgtc
    19741 tttttttgca gcaaagctag tataaggaat ctgtttattt aacaaataag agcgatagta
    19801 tgctttcatt tgactaagtt ggtcgtttgt tgctttgata atgacgttgc tcataaaatt
    19861 ctcctcgttt ttatacataa aactataccg caactcacga cttttcgttt tctaagagat
    19921 tgcgagacat agcatttttt taaagtttat catataatag ttaagtatgt gaaaaatatt
    19981 tgtggagaac ggtgaaagaa ccaacttcat ggtacactaa ataaaacttt catcaaatag
    20041 gaggaaatga ttcgtatggc gcacgaaaaa acacgctaca aagcggtgat tgccaaccaa
    20101 acatatacta ttatcggacg ggaaaccaag catcatatgg atatcgtaac gaagctgatc
    20161 aatgaacagt tagcagaatt gaaacaatta tcaccacaaa tggataatga acaagcagca
    20221 atcttgatgg ctgtcaatgc gctttcggat caattgaaga aacaagaaag aatcttggag
    20281 ctggaagaag aaacagcaga attaaagaaa aaaatgatca aatttacaga gcttgaaaat
    20341 cgtgtgaaac gcattgaagc aatcgagaac gaagctcggg aagtattgaa agaaaatggt
    20401 caagcagatc ataccattaa aaatcatgtg gaagcacaac agattttaaa cgagaaacga
    20461 aaaggacaaa ttaaacaaaa atcttctaat taagatcctt ttatcaaaat aagaaaaatt
    20521 taaaaaaagt tagaagagaa aggaacgtag catgctgagt ttgctgattt tatttttatt
    20581 gctaattgcg tttttttctg gagcacgtcg cgggtttgct ttgcaaatca tattcgcgat
    20641 tggatatgta ttgtcattta ttgctgccca gcatttttac aaaccattag caagtcattt
    20701 ggaattatac attccatacc cagctgtcac gccaacatca aagttagcat tttttgatca
    20761 ggtatttgcc tttcacctag atgaagcttt ttatgcagga actgcttttc tgattatttt
    20821 gctaattggc tggctgctta cccgatttgt gggggttttt gtccatggat tgacgtatgt
    20881 gccgatcttg agacaggtag actggattgc aggaggcatc ctgtcactaa tcatggctta
    20941 cgttactata tttttgattt tgcagttact tgcctttgtt ccattagatg tggtccaaaa
    21001 tcaattcggc gagcatagtt tcgctcgctt tatcgttgag agaacgccat ttcttaccaa
    21061 caagatgtat gagctttggg taacgaatat tttgaattaa ggaaaatagt gctggaaaat
    21121 atttcgtttt ttgtacagag tagattattt aagaaggctg cgtagcgtat gtccggcaca
    21181 gctctttttt catagtgaaa gataaggtga taaaatgaat aaccgaatcc ttgaaacatt
    21241 ggaatttgaa aaagtcaaac agatggtcag acaatttgta gtgactgcac aaggaaaaga
    21301 agaactggca gaattggtac cagtgagcga ggaacaaacg atcacaaact ggcttcaaga
    21361 aactgaggat ggattgaaag tgcaacgtct gcgaggcggg atccctatac ctaaacttga
    21421 aaatatccgt ccccatatga aacggattga gatcggagca gacttgaatg gagtggagct
    21481 tgcacaagtt tccagagtat tgtctacgac aagcgaattg aatcgtttca ttgatgatct
    21541 ttatgacagt gaaatcgaat ttgcacgttt gtatatgtgg gcagatcagt tagtcacgat
    21601 ccctgttttg agccgccgtt taaaggaagc aatcgatgaa gacggacgcg tgactgatga
    21661 cgcttctcct gagttaaaga gcataagaca gaacattcgg cgaagtgaac aagctgttcg
    21721 tgaacagtta gatgggatcg tccgtgggaa aaatgcaaag tatttaagtg atgcgatcat
    21781 caccatgcga aatgaccgct acgttatccc agtcaaacaa gaataccgcg gtgtatttgg
    21841 cggtgtagtc cacgatcaaa gtgcttcagg acagacttta tttattgaac caaaacaagt
    21901 ggtggatttg aataatcgtt tgcgtcaata ccaaatcgct gaacgaaatg agattcaacg
    21961 tattttaagt gaactttctg ctgaacttgt tccccatcgt caagaaatca tccacaatgc
    22021 ttatgtgatt ggtaaaatgg atctgatgaa tgcaaaagca cgatttggta aagaagtaaa
    22081 agctatcgtg ccgggaatca gtgaagacaa tcatgtcgtc ttgaaacaag caagacatcc
    22141 actgatcgat caggaaaaag tagtttctaa tgacatcaca atcggaaaag actatcaagc
    22201 catcgtcatt acaggaccta acacaggtgg gaaaacgatc acgttgaaga ctttaggtct
    22261 gttacaactg atggggcaag caggattacc gattcctgca ggtgaagaaa gtcaaatcgg
    22321 tatttttgag gaagtatttg cggatatagg agacgaacag tcgattgagc aaagtctatc
    22381 gaccttttct tctcatatga cgaacactgt agatatttta tcaaaagtca atgaaaaaag
    22441 tctggtatta tttgacgagc tcggtgcagg aacagatccg caagaaggtg ctgctctagc
    22501 aatcgcaatc ttagatgatc ttggtaaaaa gtctgcttat gtgatggcaa caacgcatta
    22561 tcctgaattg aaagtttatg gatataatcg ggcaaatacg attaatgcca gcatggagtt
    22621 tgatgtggat acattaagtc caacgtatcg tttgctgatt ggcgttcctg gacgaagcaa
    22681 tgcgtttgaa atctctagcc gattaggtct tgatacagaa gttattgatg aagcgaagca
    22741 gttgatgaat gatgagagcc aagatttaaa cgaaatgatc acagatttag agaatcgccg
    22801 gaaaatggca gagaccgaat atctggaaat gcgtcatttt gtttctgagg cacaagaact
    22861 tcacgatgat ttgaaagaag cttacagcta tttctttgaa gaacgtgaaa aagaaatgga
    22921 aaaagcaaag aaaaaagcaa atgaagtcgt gtcagaggcg gaagaaaaag cagaaaaaat
    22981 cattgctgat attcgtaaaa tgcaacagca gattgggcaa ggaaatgtga aagagcatca
    23041 gttgatcgat gcaaagaccc aattagcaaa tctacatcaa gaagaaactt tgaagaaaaa
    23101 taaagtattg aagaaggcga aagaacaaaa aacgttgaaa ccgggagacg aagtgttggt
    23161 tacgacttac ggccaaagag ggacgctttt acgtaaaaac gggaatcagt ggcaagtaga
    23221 aatcggtata ttaaaaatga atgtgtccga agacgagctg acgcctgttg ctcctcaaaa
    23281 agagccgaca caacgagtta tccatgctgt acgatctgaa tctagtagtc acgtgccgaa
    23341 tcaattggac cttcgaggaa aacgatacga agaagcgcta agtgaggtag atcaatattt
    23401 ggattctgcc attctagctg gttatcctca agtgactatt gtccacggaa aaggaacagg
    23461 cgcacttcgc aagggaatta ctgattatct taaaaaccat cggagcgtca aaagctttga
    23521 gtttgcaccg gcaaaccaag gcggaaatgg tgcgacaatt gttaaattta agtaaagctt
    23581 actaaaggta agcagatggt tcgctatcca agtatagaaa tgctatacta gtcatagatt
    23641 ttaaaaatgg aggtctttga tatgtcacaa gtaattacag ataagacatt taatgaagaa
    23701 acagataaag gacttgtatt gattgatttt tgggcaactt ggtgtggtcc atgtcgtatg
    23761 caagcaccga ttttggatca gttggaacaa gaatatgatg aagaagaatt cagaattgct
    23821 aaaatggatg tggatgaaaa tccagaaact cctcaacaat tcggtatcat gagcattcca
    23881 acattaatgt tgaaaaaaga tggtcaagta gtagaaaaag ctgttggtgt tcattcaaaa
    23941 gaacaactac gtcaaatgat cgatcaatat ttataaaaac ttacagcaaa aataagctga
    24001 gggtgggact gaatccagtt ccgtcctcgg tttttttgcg gttgagttaa ggttattcaa
    24061 attaatattt tttgagtata attacgttgt caggctggat tgtttttttg acagacatgc
    24121 tataataact ttaattgaat atgaagggga gtaccagatg aacgaacgaa tcaaaaacaa
    24181 attagcttta cttcctgatc agcccggctg ttacttgatg aaagataaaa atggaacgat
    24241 catttatgtc ggcaaagcca aaatattaaa aaatcgtgtc cgctcatatt ttactggtag
    24301 ccataatacg aaaacggaac ggcttgttag tgaaatcgaa gactttgaat acatcgttac
    24361 agaatcgaat atcgaagcat tgctcttaga gatcaatctg ataaagaaaa atgatcctaa
    24421 atacaacatt atgttaaagg atgataaaac ctatcctttc cttaagataa cgaatgaaaa
    24481 atatccccgt ttggtgatta ctcgtaaggt actaaaagac aaagcactgt attttggacc
    24541 atatcccgat gtcggtgcgg cgaatgagac aaagaagatc ctcgatcgat tatttcctct
    24601 gagaaaatgc aaacctagtc agacgaagga gccttgtctt tactatcatt tgggacaatg
    24661 tctgtgtcct tattatttcg acgtagatcc gaaagtctat acgaaaatcg ttgatgaagt
    24721 gaaaaacttt ttaaacggag gacacgaaaa aatcgagtca gagatccatc agaaaatgga
    24781 aaaagctgct gaaaacatgg agtttgaaaa agctgcagaa taccgagacc agatccgtgc
    24841 cattgagaca atcatgactc gccaaaaaat gacaaatact gatttactgg atcgagatgt
    24901 atttggttat gcgattgata aaggatggat gtgtgtccaa gtgtttttcg taagacaagg
    24961 aaagctaatt gaacgagatg tttcaatgtt tcctttctat aacgaagcag aagaagattt
    25021 cttgacttac ctcggtcagt tttatcagga aaatgagcat ttcattccta aagaagtctt
    25081 gattcctgat acgatcgaca agcccagtgt agaagctttg ttagctacga aagtgctgca
    25141 accaaaacga ggagaaaaga aaaaattagt tgaattggcg agtaagaatg cctcagttgc
    25201 tttgaatgaa cggtttgatc tgattgccag aaaacaggaa cggacgatcg gagcagttga
    25261 acgtttagga aacgcgatga atatcccgac cccaatacgt atcgagtctt ttgataactc
    25321 taatatcatg gggacgaatc ctgtggctgc gatggtcgta ttcattgatg gaaaaccggc
    25381 aagaaaagaa tatcggaaat ataaaataaa aacagtcaac ggaccggatg attatgcatc
    25441 aatgagagaa gtcatctatc gcagatattc gcgagtgatt cgcgaagggt tgcctttacc
    25501 tgatttgatc ttgatcgatg gaggaaaagg acaagtagat gtggcaaaag atgtcttaga
    25561 aaatcaatta ggaatcgata ttcctattgc tggcatggca aaaaacgata aacataaaac
    25621 aaatgagttg ctattcggta cagatttggc tgtagtaccg cttgagcgaa attcaccaga
    25681 gtttttctta ctccagcgaa tccaagatga agtccatcga ttcgcaatca ctttccatcg
    25741 gcagctacgc agtaaaaaca gttttgcttc ccgattagat gaaattgaag ggttaggacc
    25801 aaaacgaaaa aaaatgctgc ttaaagagtt caaatcgttg aaaaatatca cagcagccac
    25861 gacagaagaa ttacaagaaa tcggactgcc gaaaaatgtc gcacaaaacg tatttgataa
    25921 attacatcag gaatgaggaa agggcacttt acaaagaaag taaagtgtcc tatcatttta
    25981 tgtacaacaa aaagagcgtt tacgttttgt tggtaaataa taaatcgctt acgtctggtg
    26041 tctaaggata tatgtgattt cttgaagaag gagtgaagaa atgttagaag tcaaggatct
    26101 tgttaaaact tttgggaact acacagctgt cgatcatgtc tctttccaaa tccccgatgg
    26161 aaaaatcatg gggctaattg gccaaaacgg ggctgggaag acaacgactt ttcgtttgat
    26221 cttggatttt ttgacacaag accaaggaga agtgttatgg aatggccatc atcttgggga
    26281 gaaagattat gatgtcatcg gttatcttcc ggaggaacgg ggactttatc cgaaagtaac
    26341 gattcaagac caactgcttt attttgcaga acttagaggg aaatcaagaa aagagattga
    26401 accaaaaatc gacttttgga tggaaaaatt tcaggtaaaa gggaaaaaga cggataaagt
    26461 aaaatctttg tctaaaggaa atcagcaaaa agtccagctg atcgccacgt taatccatga
    26521 acctaaattg atcattttgg atgagccatt cagcgggtta gatccggtaa atgctgaatt
    26581 gctaaaagat ggaatattgg aattgaaaaa acatggttca tgtgtcattt tttctagcca
    26641 caatatggat aatgtagaaa aaatctgcga tcatttgatc atgttgcgaa acggaaaaat
    26701 ggttttgaat ggaaaagtac atgagattcg tgaatcattt ggccgtacga agttattctt
    26761 ggaatctggt ttaagccaac aggaagtaga agaaatcgaa ggcgtgaaaa aagtgatcct
    26821 tcatgaagac aatacgttag agattacctt agaagatcct gaagctggga aagaaatctt
    26881 tactcgtgcg actcagttcg gctacattcc tatgtttaac cagcaaccgc caactttgga
    26941 agagattttc aaattgaaag caggtgaaat cgatgcgtaa gttttggatt attaccaaag
    27001 atgtctattt aaaaaatgtt aagtcgattt ctttcttgat catgatatta gtccctttta
    27061 tcatgctggg tatcatttat gtagcaggaa actttgctca acaaaatagt gatgtcaata
    27121 aaatcggcgt attggctgat aatgagcaaa tcagtcagca aatgagccaa gtcaaaacag
    27181 atgattttga gttcaaagca gttgattctg aagaaaaagc acaaaaagag ctttcggaag
    27241 aaaaaatcga tgcgtattta gtagtctcaa ctgagaatga taagataaat gggatgcttt
    27301 atagcgaaaa ttcattagga caaagtacac aactactgat acaacaacaa ctgactggct
    27361 tgcaatcgat gcttcgagcg agtcaattag gcatttcacc agaagaagta gctagcttga
    27421 gccaacaagc aagtttgact cgacaaaaag tcaattttga ttcaaaagga aaaatgacag
    27481 tcggagaaga taactcgaca gtccaatacg tcgtaagtta tgtagcaacg attgtcttgt
    27541 tcattattat tttgacgtat gcgcagatca ttgcacaaga gatcgcttct gaaaaaggca
    27601 cgcggatcat ggaagtgatc ctgtccagta cgactgcaca aaagcatttt tacggaaaat
    27661 taacaggtgt tttacttgtt gcattaacgc aaatggcatt atacggtatt atttttggta
    27721 taggatacag tcaattcaaa gatatggaaa tggtcaaaaa tatattagac ggtatctcat
    27781 tggataactt gattggacca ttcttgtggt attctcttct attcatgatc tttggcattt
    27841 tgattttttc tgttttagca gctttatgtg gctctttggt caacaaagca gaagatacag
    27901 caaaagcaat tttgccagtg acttatctat ctctaggcgg atacatgctt ggattgatac
    27961 taggagcttc agatccaaac aatatcgtta ttcggatcac ttcgtatatt ccattcttat
    28021 cttcatatat tatgccggtt cgcttagcaa atgagacagt cggtatgggt ggagcattga
    28081 tttccttgtt ggtacttgta gccgtaacat tcttattgat gatcttgtct gcaaacatgt
    28141 acaaatcgaa tgtactcgtt tatagcgaag gcggattatg gagttcattg aaacaatcga
    28201 tttcaattat gaggaatgaa cgaaaaaaag cataaaacaa tcctaaaata cagaaggaag
    28261 ctggacatct attgttccca gcttcttttt gtatagacct attttattta ttttactata
    28321 ttggatatat attcattgaa aatagtgtat aacaacttta taatattgag tataccaatt
    28381 tttggaggcg ttttaatgga ccgttattta gatttacttt cagaaaaatt cccctcaacg
    28441 gaggatgtca tcacggaaat catcaatctc gaagcaattt tgcagcttcc aaaaggaaca
    28501 gagttatttt tgagtgatat acatggcgaa tttcctgctt ttgatcatat tctgcgtatc
    28561 ggttcaggaa atcttaaaga aaagatcaaa gacctttttt ctgaacaaat gacggaaacg
    28621 gatatcagcc aattcactat ttttacggct tatccagaat atgcattaac gactgattgg
    28681 tacaaagaac aagataaatc gcagctgatc catcatttga tcgatctttt acggtttacg
    28741 acagtcaaat atacccggtc aaaagttcga aaaggattgc cgaaagaata tagctatatc
    28801 attgaggaac tcttgtatat cgatgaccgt atcaatggaa aaaaagacta tgtaaaaaaa
    28861 atcattgaac aacttgtttt gatgaaggaa gaagaaaaat ttttaacgaa acttgcacag
    28921 acgatccaaa aatctgtcat cgatcatttg catatcgttg gagatatttt tgaccgagga
    28981 actcaagcag ccaaagtgat ggatcgaatc atggattttt cttctgtaga tatccaatgg
    29041 ggaaatcatg atattttgtg gattggtgcg tattgcggct ctgaggcatg tttactgaca
    29101 cttttacgga ttgcagcacg ctataattat ttatttgaat tagagaaaga atatgggttg
    29161 aatttacgtc cattgttttc ttttgctcat caaacttatc agaagaatcc agtatttgcg
    29221 cctaaaaaca gtaaaaatct atccgaaaga gagcaagaag aattagaaaa aatccatcag
    29281 gcactttcta tccttcaatt caaatcagaa catcagttat tggatcgtcg acctgaattt
    29341 aaaatggacg atcgtaaatt gctggaaaaa atcgactatg aagcatcaac gattgattta
    29401 gaaggtcagc tctatgagtt gaaaggaact tgttttcaaa cgatccagcc agatgatcca
    29461 aaaaaattct tggaagagga acaaaaagtg attgatagtt tgatgtattc attccagcac
    29521 tctttgagaa tgcaaaaaca tatgacgttt ttgatcgaaa aagggggaat gtatctcacg
    29581 aacaatcagc atgtgctgtt tcatggctgt atacctgtag acgagaaggg acagctctta
    29641 gcatttgaat tagaccaatc ttatcgcgga aaagaactgc tgggcttttt tgaaaaacag
    29701 ataactgaaa gcgcaaaaga tctgactgca aaagaagatt tagcaaccga tttgatttgg
    29761 tatgcgtgga gtgggccatt ttcgccttta ttcggcaaga gtaaaatggc gacttttgaa
    29821 cgttattttc tcacagagcc tcatacgcac gtcgagaaaa gcaatcctta ttatcacttg
    29881 cgagatgaag agtggttcag tgaaaaaatt ttagcagaat tcgacacaaa agaagaaggg
    29941 tcagcaatca ttaatgggca cacgccagta aaagtaaaaa aaggggagtc accgatcaaa
    30001 gcaaatggaa aagtatttgt cattgacgga ggtttatcca aagcttatca aaaaacgaca
    30061 ggaattgccg gttattcact attatgcaat tcttatggtt tccaaatcgt gacacattat
    30121 ccgtttttgc ctattgaaca acaatttgca aaaaaatccg accaaacaaa tgtgaaaaaa
    30181 gtaatcgaac agcaactacc acgcaaactc aatcgtgata caacaaaagg tatggaactg
    30241 cagcagcaga ttacccagct caaaaggctg ttggactatc gaaaggacga ttgagaagaa
    30301 ttccagtgaa cattgttcca tagactggag actgagacaa aagtcgtgtc gcagtctctt
    30361 tttccggata aacggtgttc ttctgccaac tcctcggtca caagtcacac tattcaacaa
    30421 acatgaaaag ctgttttttg aaattgctcc ttgtgactca gagttgaacg gcaggctcac
    30481 gacctcttgg tataaacggt gttcaaaagc cagtttctcg gtattaagcc aaatttatgc
    30541 aaaaatgtga aaagccattt tcacaaaatt tttcttaata ctcgaaacta aacagctttt
    30601 tcacaacccc ctcagaaagt ctattaaaat tcattcacaa agaaatcgaa taagcgctgt
    30661 tcagatggat gtacacggtg ggtaagttcc ggatgccatt gaacaccgag gattttatgc
    30721 atatcatctt tgctttgaac cgcttcaatg agtccatcgt tagaaaaagc gatggctttt
    30781 aataaaggtg aaagatcttt gactgcctga tgatggtaag aattcacaaa atatggatcg
    30841 gggagaaggt tgcttaacaa actgtctgaa acaatcttga cttcgtgagt cgtaaattgc
    30901 ggggcagtgg gctgttgttc atgttttact gaccactttg gatataatga aagatcttga
    30961 taaagtgtac cttccaaaac gacattcaat agttggagtc cccggcagac tgcaaaaatt
    31021 ggttttcttt gtttcaatgc ttccaagatc agtgcctgtt caaattggtc tcgttgaata
    31081 tttgtttccg ttagctttgg atgaggatct tccatgtaaa gttgtggact gacatcttga
    31141 ccacctgcaa gaataagttt gtcgatttgt ccaatcagtt gaggagctga atctggagac
    31201 atgactggca gaataagagg caatccttga gcatctaaaa ctgcatccac gaatccttgc
    31261 ggtgtatagc tcacttgatt tccttggaaa gtatctgttg ctcgaatcag ttgatttccg
    31321 gcaatgccga tgattggttt catttgtatt ccccctaaag tagacttatt gtaacaagga
    31381 tttaaaaaaa attaaactat gtaagacttg cccctatact tatctgttct tgctgtgtta
    31441 ctatctgtaa agagaaattt cgtgtgaaat tcatgacgat agttgaaaat attgcttaat
    31501 ttgttataat aaaaagtaag cagaaataaa aaggttgggc gtaagcttca aggatctagt
    31561 tcttcaaggg gtgagaagga cattttattg aaggggcctg cctatactaa gttatcttta
    31621 gaggtacata ctttcaatga aaaaagaaag catgtacctc ttttttaaat cgaaaggaag
    31681 tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc agaagaagaa aatgaaaagc
    31741 gtgctcaaac actgcggcag cagctgaaga tctatgcaac agaaaaagag caggaattgg
    31801 aaacgatcca aacaaactat cgacaacaac taaaacagtt ggtggaagaa aaagaacaat
    31861 ttgaaataca agaattagaa aaagaaaaaa tgaaattgaa agcagaagca gacaaggtgc
    31921 aagcaacttt gaaagatcaa tatcaaaagc atcagagtca agcgatcggt gcgatcattg
    31981 aaagggtgaa agaaacttat ggccgtcact aagatggaaa aagtgaccct catttcagat
    32041 aaaagaaatc aggagaggat tttacaagca gtacaaggaa tccaaaacgt tgaaatccgg
    32101 gatctgtatc aaaatagaac aaacaaccag tgggtggaga agtattttcc agataccacg
    32161 attattgata aagaagcaaa attaagcgct ttaggtaatc ggttgaaaga catccaagaa
    32221 gctatccaat tcatacaaca ccacggcgat agccgtcaaa agaaactcca tttgaaacgt
    32281 caagaacttt ccttacaaga tttggaagcc aattattccg aagaaaattt cataaataaa
    32341 ttgaaagaag tccttgattt aaaagaaaag tgggaacaac taactgaaga acgtgatcgt
    32401 ttagaagaag aggaagaatg gcttcttcat tggcaacagc tggatattgc tccaagtatg
    32461 tatgcaagta agacgaccat ttttgagatg gggactgtga gtgcagcaaa ttttgaaagt
    32521 ttcaaggaag aactgagtaa gcttgatgac gtttatatgg aagaaataga ttatacgcca
    32581 aaacaagttt atctttcgta tgttgcttta aaaaaatcag ttgctgttat agaagaaatt
    32641 gctgggaaat acgggttcaa taaagaaacg tatccttatg aacaaaatcc taaagaaaaa
    32701 ctgcaagaga ccaagcagca attatccatt gttcacgagc agcaaaagaa gataacgaca
    32761 gcgttaggtc agtgcagtgg ctatatccaa gaatttgaat gggtagaaga agtcacactt
    32821 gccgttgcag aacgagaaaa aataaaagaa cggtttatcc atgcgactta tctgatcgtt
    32881 ttgcaaggtt gggtagatgc agaagaaaaa cagaatttgc tgcatgtgtt aaacgaaacc
    32941 gtatcagaag aagatatata cgtcagtttc gaaacaccaa actcagaaga gattcagcag
    33001 gaagtcccta ctaaattgaa aaaccatccg cttgtcgaac cttttgaatt gctgactgaa
    33061 atgtacagtc tgccaaaata tgaagaagta gatccaacac cttggatgac accattttat
    33121 cttgtcttct tcgggatgat ggtcgcagat gttggttatg gtttgctgat gctcattggg
    33181 acaatactag ctcaaaaact acttgttcta ccacgcggga tgaaacgttt cgtaaaattc
    33241 tttgagattc tctcgatacc atcgatcatc tggggattga tctacagttc atttttcgga
    33301 cagtcattac caaaagaact gtttggcatc cgcttgcctt tcccaatcct atctacgacg
    33361 gatgacgtca atacgatttt gattttatcc gtgattttcg gtctgataca gattttggtt
    33421 ggattatttg tggcagcaaa ggaaaatatc aggagaaaag attacttgag tgctgtcagt
    33481 gatggatttg cctggcaagg gatcctaatt gggatcgtta ttgcgttggt tggtgccatg
    33541 ttgataaaaa atacagcatt tgtttacctt ggcgctgggc tatcgatcat tgctgcctta
    33601 tgtatcttga tcgttccgat tatccaaacg ccgtctaaag tcaaaggtgc tgccaaaggt
    33661 gcgtataatc tttacggact gaccggctat atcggtgatt tagtcagtta tacacgtttg
    33721 atggcattgg gtatttcagg cggaagtatt ggagcggcat tcaatatgct agttgctttc
    33781 atgccgccag ctgctcgatt cagtgtaggg atccttttga tcatcgcttt acacgcactg
    33841 aatatgtttt tgacactgct aagtgcctat gtccatggcg cacgattgca gtatgtcgaa
    33901 ttttttggga agttttatac aggaggcgga cgtgcctttg atccgctgaa aacggcggaa
    33961 aaatacgtca acatcaatca caagaaaaaa aacaataaat aattggagga tttttatata
    34021 atgatggatt acttaattag tcaaaatggt ggaatggtat ttgcggtatt agcgatggca
    34081 acagcgacga ttttttcagg gatcggttca gctaaaggtg ttggaatgac aggtgaggca
    34141 gcagcagcat tgacaacaag tcaacccgaa aaattcgggc aggctctgat tctgcaattg
    34201 cttccaggta cgcaaggttt gtatggattc gttattgcct ttttgatttt tatcaactta
    34261 ggaaatgaca tgtcagttgt acaaggactg aactttctag gtgcttctct gccgattgct
    34321 tttacaggct tgttttcagg tattgcccaa ggaaaagtcg cagcggcagg tattcaaatt
    34381 ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt ttgctgcgat ggttgaaaca
    34441 tacgcgattt taggtttcgt tatttccttc ctattagtgt tgaatgccta agcataaagg
    34501 aggaaaagca gatgaacgcc attgaaaaaa tcatctctca gatgaacgaa gcagcagagc
    34561 aggaaagagc ggcgttagaa caagaagagc gaatgaagat cgatcaaaac tttgaacaaa
    34621 aacgtacgca agttgaaaca gaacatcaaa aacaaaaaga aaaacaaatc gaattactcg
    34681 aaaaaaaata ccgtcagcta aggaatcgcc agcaagtaga agtacgacaa gaaaatttga
    34741 atgcgaagca ggaattttta agacgattgt ttgcagatgc ggtaactgaa atggaaaatt
    34801 gggatgaatc tgaacaaatc cagtttatca aaaatgcatt gtattcatta cctttgacag
    34861 gaaaagtagc attcattgct ggagaaaaat cagcagccta tctttctcag acgttgttgg
    34921 atgaatggaa caatgaactt ccctttatga tggttttaag tgatgaaact gttgctgatc
    34981 aagcgggttt tctgataaac gatcaaggag ttcagtataa ttttcttttc agcagccttg
    35041 tacaagatat ccaaggaacg atgagttttg agattgccaa tcaattattc gaataaggag
    35101 ggatcagtgt atggaatacc acgaactaaa tcccttgatt cgcggaagag agcttgaact
    35161 tttgtccaat gagacatttg aacggatgat tcaaacaaat tctgtcgaag cacttggtga
    35221 aatattgaaa tccacgattt acagtccata tatttatgac ggatatgaat atgacttcga
    35281 acagaatctt ttaaaggagc agagccgtct atttcgctgg ttaaaggaat cagcaccgga
    35341 gcctgaaatc gtttggatct atacgatgcg ttatactttc cataatctga aggttttgac
    35401 aaaagctgag atgacaaatc aaaatctgga ccatttgtat atcgacgatg gattttattc
    35461 attagaaacc ttgaaggatg ccattcatac gcaagtttca aatgaacttc ctgaaagcat
    35521 tatggacagt atacgagaag tacgtgatta ttttgaagag tctaccattc ttcagggaat
    35581 tgacgtgatt tatgatcgac agtttttgac agagcagcga cggcttgccg ataagctagg
    35641 atatcaagaa ttgctgacag aagtcattgc ttttattgac ttgaccaata tcacaacgat
    35701 ggctcgagga atattgcaga aaagaacata tgggttcatg acgacggtac tttccagctc
    35761 gggaagtatc gaaaaagaag tatttttgaa ctttgtagat aaagatatgg aagattacac
    35821 gaattttcta ttagagacag attatgctga ttttctgcgc cctgtcatcc gtgagggaaa
    35881 tattgatctc gtaaagcttg aacagttgaa agatgattat ctaagttcat tgtatcaaga
    35941 agcacaaacc caggctttcg gaccactgcc actactagcc tttttgaacg caaaagaggt
    36001 agaaagcaaa aaccttcgtt tactggttat cggcaaaaga agccatttcg aatcagaaac
    36061 aatcagaaag cgggtgagac aagtctatga cgcataagat cggtgtagtt ggcgacaaag
    36121 attctgtttt gccattcaaa ttgtttggct ttgatgttcg ttatggtaca accaagcaaa
    36181 ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta tggcgtgatt tatgtcacag
    36241 agcaatgtgc agcattgagc ccagaaacga tcgaacgtta caaggaacaa atgatacctg
    36301 ctatcgtatt gattcccaat catcaaggat cattagggat agggctggaa gaaattcaaa
    36361 aaaacgtaga aaaagcagta ggtcaaaata tcttatagta tgaaaaggag atagaaattt
    36421 tgcaaattgg aaaaatcata aaagtctccg gacctcttgt aatggctgag aacatgtctg
    36481 atgccagtat ccaagacatg tgtctagtgg gagatctagg agttatcgga gaaattatcg
    36541 agatgcgtgg cgatgtggcg tctattcaag tatatgaaga gacttctgga attggtccag
    36601 gcgaaccggt tcgctctact ggtgaagctt tatctgttga attaggacca gggatcattt
    36661 cacaaatgtt tgacggaatc caacggccat tagatacctt tatggaaatc acacaaagta
    36721 atttcttagg gcgcggagtt caattgcccg cattggacca tgagaaaaaa tggtggttcg
    36781 aaccaacagt agaagccgga gaaacggtga gtgctggaga tgttatcggg atcgtagaag
    36841 aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg gataaaagga acgatcaaaa
    36901 caatcgaaaa aggttcattc actattgatg aaacagtatg tgtcattgaa accgaaaatg
    36961 gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag acgtagtcgg ccaatcaaag
    37021 aaaaattaaa cccggatgca cccatgatca ctggacagcg agtgattgat acattcttcc
    37081 cagtgacaaa aggaggagca gcagctgtac ctggtccttt tggtgcaggg aaaacagtcg
    37141 ttcagcatca aattgcaaaa tgggccgatg tggacatggt tgtctatgtg ggatgtggcg
    37201 agcgtggaaa tgagatgacg gatgttttaa atgaattccc tgaattgatt gaccctaata
    37261 caggagaatc gttgatggaa cgtacggtat tgattgctaa tacatcaaac atgccagtag
    37321 cagctcgaga agcttctatc tatacgggaa tcacaattgc ggaatatttc cgtgacatgg
    37381 gttatgacgt tgctatcatg gcagactcca cttcacgatg ggcagaagca cttcgtgaga
    37441 tgagcggacg tttggaagaa atgcctggtg atgaaggtta tccagcttat cttggttcac
    37501 ggcttgcgga atactatgaa cgatctggaa gagtcattgc attaggatca gaaggtcgcg
    37561 aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg aggggatatt tcggaaccag
    37621 tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg tcttgattcc agtttagccc
    37681 aaaaaagaca ttttccttcg atcgattgga tacaaagcta ttctctttat tcaacagaag
    37741 tagggaagta tatggatcat atccttcaag ctgactgggc atccatggtc accgagggca
    37801 tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt gcgtttggta gggattgatt
    37861 ccctttcaga taatgaccgt ctgacattag aagtggcaaa atccattcgt gaagattatt
    37921 tgcagcaaaa tgcttttgat gatgtcgata cattcacttc aagagagaaa caattcaaaa
    37981 tgttgaagat gatcttgacc tttggtgaag aaggacgccg tgcgttgtcg ttaggtgctt
    38041 atttaagtga gatcatggac ggtaccgtat cgattcgtga aaggatcgga cgaagcaaat
    38101 atatcccgga aacagaatta gaaaaactag atcaaattat tggtgaaatc aagcaaacga
    38161 tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta aagaatatcg tacgatcggt
    38221 gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg gtgtcaaata tgaagaatta
    38281 atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac aagtattgga agtccaagaa
    38341 gataaagcaa tggtccaaat attcgaagga acaagtggta tcaatttacg tgactcttct
    38401 gtacgatttt taggccatcc tttagaacta ggtgtatcgg aagacatgat cggtcgagta
    38461 ttcgatggtt tgggacgacc gaaagataac ggaccagaga tcctgcctga aaagcatttg
    38521 gatattaacg gagaagtaat caatccagta gctcgggatt atccagatga gtttatccaa
    38581 acaggtatct ctgcaatcga tcatttgaat acattagttc gtgggcaaaa attaccagta
    38641 ttttctggct ctggtcttcc tcataaagaa ttagctgctc agatcgcgcg acaagcaacg
    38701 gtactcgatt catcagatga tttcgccgta gtctttgctg ctattggaat cacttttgaa
    38761 gaagctgaat ttttcatgga agattttcgt caaacgggcg caatcgaccg ttctgtcatg
    38821 tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg ctactcctcg tatggctttg
    38881 actgctgcag aatatcttgc ttatgaaaag ggaatgcatg ttttggttat catgacagac
    38941 atgaccaact atgcagaggc attgcgagag atttctgcag cacggcgaga agttccagga
    39001 agaagaggat atcctgggta tctttacacg aacttagcta ctttattcga acgagcagga
    39061 agaatccgcg gactaaaagg atcggttact caaattccga ttctaacaat gccagaagac
    39121 gataaaactc atccaatccc tgacttgact ggttatatta cagaaggaca gatcatcttg
    39181 actagagagc tttacaagag tgggattcag ccaccaattg atgtactccc gtctctttcg
    39241 cggttaaaag ataagggaac tggacccgga aagacaagag aagaccatgc agctacgatg
    39301 aatcagcttt ttgcagccta tgcacaagga aaacaggcaa aagaattagc cgtagtttta
    39361 ggtgaatctg ctttatctga tgtagacaag atctatgcga agtttgctga gcggtttgaa
    39421 aaagaatatg tcaatcaagg attctacacg aaccgttcga ttactgaaac acttgatcta
    39481 gggtgggaac tgctatcgat gttgccaaga accgaattaa aacgaatcaa agacgacatg
    39541 ctggacaaat atctgccaga agggaagtga gttctgatgg cacgattgaa tgtgaatccg
    39601 acccgcatgg aattgactcg attgaaaaaa cagttgacaa ctgccacaag agggcataaa
    39661 ttattaaaag ataagcaaga tgaactgatg cgtcaattca tcctgttgat tcgaaagaac
    39721 aaccagctgc gtcaagaaat ggaagagtct atgacagaag caatgtctga ttttgtattg
    39781 gcaaatgctt cgatcacgga acctttcatc gaagaattat ttgttttgcc ggcggaaaac
    39841 gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa aagtacctgt gatgaatttt
    39901 gaatatgatg aacagctgac agacacacct ttggaatacg ggtatttgaa ttccagtgcc
    39961 gaactggatc ggtcaatcga tcggtttact accctgcttc caaaactttt ggaactgaca
    40021 gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg aaaagacacg tcggcgagtc
    40081 aatgcattag aatatatgac gatccctcaa ttagaagaaa cgatctatta tattcgtatg
    40141 aagctggaag aaaacgagcg cgcagaagta acaaggttga tcaaagtaaa aaatatgggt
    40201 accactgact aagtggtatc tttttttaaa agaggaaaac gatgattaaa caaagcaaac
    40261 aaataaagaa acgtttgccg gctgttcagc ttctcgcatt aggatttttt ctcctgattt
    40321 tagttggcgg cggcctactt accctaccat tttttagtaa tagtgggcat gggacaaatt
    40381 ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt aacgggattg acaacattga
    40441 atacagcaga gcattggaac agtgctggtc aatttttgat catgcttttg attgagatcg
    40501 gcggtcttgg ttttatgatg gttccgattc tatgctttgc attgataaag aagaaagtca
    40561 gtctcagcac acgtattata ttaaaagaag cgctgaatct agaagaagta tcaggtgtga
    40621 tgaagctcat gctttacatc ctaaaattgg cctttgtgat ccaattgatt ggtacggttg
    40681 ctttatcttt tgtatttgtg cctgaatttg gctggttgaa aggtatctgg tacagtttgt
    40741 tccatgcaat ctctagtttt tgtaatgcag ggtttgattt gttaggagac agtttagcca
    40801 atcaccagca aaatgtttat ttgatcatgg tggtatctgc tttgatcatt tctggtgggt
    40861 taggcttcat cgtatggcgt gatttactgg aatatcatca gaaaaagaag atgacgattc
    40921 attcaaaaat cgcattaacc gttacaggta cccttttatt aggcggattc gttgtgttct
    40981 ttttcacaga gcgcaatggg gcaacgctag tggaagggaa tatgtttcaa cgattggcaa
    41041 acaccttttt tatgagtgtg acacctagaa cggctggata ttattcagtt gattacctcc
    41101 atatgagcca tgcaggtctg attttaacga tgtttttgat gtacatcggc ggaacatctg
    41161 ggtcgacggc cggcggattg aaaacaacta cgttaggtgt gttgctgatc cagatgcgtt
    41221 cgatgttgaa aggacgtacg agagcggaag catttggccg taccatccga caaggcgcag
    41281 tgttgcgggc acttacttta ttttttgtta cgttgacgtt gtgtgtagtc gccatcatga
    41341 ttttatcggt gactgaaacg atacctaaaa cttctggcat cgaatatatt gcttttgagg
    41401 tcttctctgc gtttggtaca gtaggtctta cgatgggatt gacgccagac ttgactgcaa
    41461 tagggaaatt gatcattata gcgcttatgt acattggacg agttggtgta ttgactgtgg
    41521 tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa atacaaatat ccagaagaaa
    41581 gtgtcatgat tggataattt catcttctga cagaaaccta gtgatttagt aaaataagaa
    41641 aataaaataa tttttcttgc ttcttggata ctttaagtgc aaaatgttcg tttatttttt
    41701 gaggcactac ccgttgttga acctcgggta gtgcctcttt tttattgaaa ggaatcaata
    41761 agatttgatt cctttattta tcaataggtt ataattcata tttttttatt ttttctttta
    41821 cgatacttag tccagaagct aaaatttcaa ggttattaga ggatagggaa attcgaacga
    41881 atgcatctgg ttgcgtacgt gtagtaaagc gtctggaatg ataaagtcgg ataccgttag
    41941 caagaaagtc attctcaatt atcttagggt caatctcagg atcaactgga agaattcgat
    42001 agtaagggac acgattcgtt ggtttttcta ctttgaaaag agaatcaaaa agctgattgg
    42061 ctctttttgt aagacttaat ttagtttcta agatcctatt tgcttcattt gaatggagga
    42121 tttgagtgat gacttccaca tctaatccag aagttttcac atttatatta aaaattgctt
    42181 gttctatctt gctttggaca tgtactggaa ctacaagata agcaactcgc aatccagaac
    42241 aaataaattt tgtcattcca gctaagtaga ttgtttggtt aggtaataaa ttttggaaag
    42301 gaggaatgat cgtatgttga tagtaagttg ttaaaaatga atggatatca tcttcaataa
    42361 cccatagacc ttctttttca atcacttcgg ctaattgctc tcgtcttttg tgagagattt
    42421 gaaaccctat aggattatta caagaaggca taagaaagac accatgaatc ttcttttttc
    42481 tacattcctg aatcaatata tcaggtcgca ttccttgctc gtcaaaatca attggaacga
    42541 tctctaaatg atataactga gccaattcaa tgaaattagc gtatgtatat cggtctgttg
    42601 ctattctatc acctggagag aaaagtgcag aaagtgtgat agccaatcca ttttgaacac
    42661 cggaaacaat agatagagat tctaaggacg gaatgactcc ttgagttttt aaccaatttg
    42721 ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg gtaattaagc aaaccaacaa
    42781 gatttgggtt attactagtt gattgaataa acgggacaac gaatttatta cattcttcaa
    42841 aagaactaac cagaccaaaa tcaatgatat gttcggttac ttcattggta gagatggtga
    42901 tggactcaaa gacattggga gaaataaatg tgccacttcc aatattcgta tacagcaaac
    42961 ctttctcaat tccatattta taagccttgc caacggtagt aaaatttaaa tctaaataat
    43021 cagctagctc tctttgggag ggtaactgag tgtttttctg taatttattc tttaaaatat
    43081 cttgttctaa ttgttgaatc aacgatcgat aataaggacg cttcaatttt tgtttgtctg
    43141 gtcgccaagt taacgggtaa ttgtcataag aattaatagg cattttctcc actccttaaa
    43201 attgtatacc atacaatttt accattgatt gtattgattt tagaagttaa tcttttgtga
    43261 ggagggaatt gtctatgaaa attattaatt ttgaggaagt agtagcttct tttagttttg
    43321 aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta tgaaagtggt aaaatcagcc
    43381 aaaatcctcg attggtggaa attttacctg acggaaaagg caaaaatatg tttgcgatga
    43441 tgcctgctta tttgggggag aacagatatt ttggcacaaa agtcattacc gcttttccgg
    43501 ataatcatca gtatcattta ccttctcatt taggagagat tttcttgttt gatgctcaaa
    43561 acggactacc caaagcattg ataaacgcaa atgcagtcac ctggattcga acagctgctg
    43621 tatctgcgct ggcaacagat tacttagcaa atccgcatgc agaaacactt gctttaattg
    43681 gagctggtca acaagcattg tcgcatttga ctgcgatttc taccattcgt cccatcacta
    43741 cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac ttttatcgct aaagctaaaa
    43801 aacagtatcc taaaataacg tttataaatg caatatcagt agaagatgca gtacgtccag
    43861 cggaaatcat ttgtacgttg acctctagta aagaggcatt tcttcaaaaa gagtgggtaa
    43921 gggaagacgc acatatcaat gctgtgggca catttactcc tgatacaaga gagataagta
    43981 catcgttgat ggaaacttct caaatctatg tagatgatta ctcagctgcc ttaacagaaa
    44041 gcggggacct gcttatagcc atggcagaag gagatttaga ggaatcttgt attgttggta
    44101 cattaggcga attagtttct gagaaaaaaa cattttataa aggagaatcg aggccgacga
    44161 ttttcgacgc agttggtcta gctattgaag atctttgttg tgcagaatat atttataaca
    44221 aattagagaa aggggcttta aaatgaactt agattattac gtagttgatg catttgcaga
    44281 tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta gaagaatggc tgccagaagg
    44341 tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa acagcattta cagtgaagaa
    44401 aaaccaagaa tttgagctta gatggtttac gccagatcga gaaatcgatc tttgtggtca
    44461 cgcgacatta gcaacagcat ttgttttatt taactattac aaaatacctg atgaaacgat
    44521 taaattttct actcaaagcg gtaatctatt tgtgacaaga attaaagatt attattacat
    44581 ggattttcct agtattatgc cgaaaaaagt gccgatattg tctgaatatg aagaagcgat
    44641 tggggctaag attaaagaag cctacttagc acgtgattta tttttcgtat tagaagatga
    44701 aaaaacggtg gctaaattgc agccagattt tacagctatc aaaaattttg aattaggaat
    44761 aggagtcatc gtgacagcag aaagtgtgca aaaagacttt gtttctagaa ccttctttcc
    44821 aaaattaaca atcaatgaag atccagtatg tggatcagca cattctaatc ttattcctta
    44881 ttgggcagaa agaatgaata aaacaaaatt gtcagcttat caaatgtcat caaggggcgg
    44941 ggatctagaa tgtgaattaa aagaagatcg tgtgataata ggaggaaaag cagttttgtt
    45001 ttctaaaggt acctcgttta tttgatttct ttcaaatgaa ttaaaaataa attggtggag
    45061 agtggcaacc ttatagctac aatggttgtt aaaaaaagac gcaaactttt tcaatttaat
    45121 gaaaagtttg cgtctcattt taattattgg tgtttgtttt ttattcaatc aagagtaaaa
    45181 tgccccatac taactatcct cggatgactt cgattttata accatcaggg tcaatgacaa
    45241 agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc agtaatctca agaccagcag
    45301 ctttatgttg ctcgtgtaat ttttctagat catcagctgc tatagcgata tgaccatagc
    45361 cgtctcctag atcatacgca ccatgatcat agttgtaagt caactctaat tcatagtcat
    45421 ccccaggaag tgtcaaataa acaagtgtaa atttgttttc tggaaaatca cggcggcggc
    45481 tttcttcaaa accaaatgcc ttttgataaa attcgattga tgcttcaaga tctttcactc
    45541 gaacacatgt gtgagccatt ttcatagatt catctctcct tttcctttta ctcaatcata
    45601 acaaaaagaa gtaaggaaat agttgatttg tgcttgttca tgagaaattt ctcatgtaaa
    45661 atggatagaa aataaaactg ttaaggtgga aactattcat ggataaacca atttttggtg
    45721 aaaaaaagca atttgctgat tatcaaaccc gttatgcagc atatattgtc atagaaagag
    45781 atcagcagat tgcagtaatc gaggctccaa atggtgcttt ttttcttcct ggcggggaaa
    45841 ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga gctgatagaa gaaatgggaa
    45901 ttgtggcaga aatttcttct tatctgggag aagctgatga gtatttttac tcgaattatc
    45961 gtgcaactta ttattataat ccaggatatt tctttgttgc tgattcttgg aagcgtatag
    46021 gagaaccaac tgaaaagacc aataaaattt ggtgggtgag ccctcaagaa gcgcttgtga
    46081 aattgaaacg tggtagccac cgatgggcag tcgagagatg gatcgaaaaa aataaaaact
    46141 gaaagaaagc gagtagatca gctttctctc agttttttta tttattacag tacatatttt
    46201 ttgattgctt cagctacacc gtgctcgttg tttgatgaag tgatgacatt tgctgcttct
    46261 ttgacaagag aaacggcatt tcccattgct actcctagac cagcatattc aatcatggat
    46321 aagtcgttct cgttatctcc gatagccatg atttcatctt gatcaatacc aaggtgctgt
    46381 gcgagattcg caactgccgc acctttactt gcttctttat ttagtacttc gaagtaatag
    46441 ggcgcacttt tgaccgttgt gtatttatca cggaaagttt gcggtaaacg cgcaattgct
    46501 gcatctaaaa tttctggttc gtcgatcatc atcattttga cgatgttcat gtctggtgtc
    46561 atttcttcag gtgttcgata ttttagcggc atcttgacta aacttgcttc gtggatcgta
    46621 taagcgctga tatctcgatt aggcgtgtag atcgctttgt catcgatcga atggagatga
    46681 ctgccgacac ggcgtgccat cacttcgatc tctaggaaat cttcatgtgt cagtccgtga
    46741 cgggcgatga ttttacctga tttcgtttgt tgtacgagtg ccccgttata agtaataacg
    46801 taatcattat cttgaaaaag gttcaactcg tttaactgtt cctggacacc tggtaaggga
    46861 cggccagtgc ataaaacgat cgaaacacct tttgcaacag cagcggcaat cgcttctttt
    46921 acttcttttg ttacttctct tttctcattt aataaagtac catcgatgtc gatagcgact
    46981 agtttgatag acataatttc ctccaatata ttttaattta tttcaatcaa tgcgccatta
    47041 cggatatggc tggcaaattc ttgataagtt tcgtcaaata aatcataatg atcacgcaag
    47101 gacggatcaa ccatttcttt tggaaagaaa aatcgctcat ctccttgttc ttgtcccgct
    47161 aatgcagcaa caagctgact aacctgtgat aattctatca aagttccgtc atttcgcaaa
    47221 atctcgattt gtgtgcgatg tctgccttgt tctgggcgat aaaaatcata aggtagatcg
    47281 tagctagaat tcacagcagt gtaataaaca ggattatatc cgaccttttc tactaacaaa
    47341 gtgagttctt ggactaattt tgaatcccgg ttgccagaaa aagtagcaga tttcagtggt
    47401 ttacgattca aaaaacgttt agctaaatca tttaaaatag gatcagcaga ttcagaccat
    47461 tgagtaaagt aagtgcccaa gaccccatca tcaagtttga ggtattcttc taaagtaaag
    47521 cttccgtcaa gaaatggcag aagtaattga gaatggagtt caaaactgct ggcatcttct
    47581 tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa ttacttccat accacgggaa
    47641 acaggatgga agtacacttg cacatacatt tgatatcggc taacgatata atcttccact
    47701 gcatgcatgc cactcatgga aaaagcgatc ccgccttcat aaggacgaat cacacgtaat
    47761 attcgggtaa gatcaaatgt tccatattct gttccagtga aataagcatc ccgaagcaaa
    47821 tagtccattc gatctgcatc gatctgacta gaaatcattt ggacaacttg tgggttgggg
    47881 taagtttttt ggatcacact agctaccttt tcaggaaaac cttcttctac tcggttaaga
    47941 atctgataca cttctgtttc tggagaagtg atgatctcta cagtgatggc ttcatgattc
    48001 gtatggaaga tatgttcaaa tgtatgagag taaggaccat gaccgacatc atgcaacagt
    48061 gccgcacata aagtcaccag ccgttcctga tcatcccagc ctccgttgcc tattttttct
    48121 tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg aaatctcata aacgcctaat
    48181 gaatgagtaa aacggctatg ttctgctccg tgaaaagtga aagaagaagt gcctaattgt
    48241 ttaatgcgtc gtagacgttg gacttctttc gaattgatca aatctaagat tacttgatgc
    48301 tggacatgga tatagttatg gactggatca cgaaaaactt tttccatagg cagcatttga
    48361 tatttataag gggttgtcat aatgtagctc ctttatgtta ttacgttgtt ccattctctg
    48421 gatttggttg ttccattgct ccagctggat ttcttttttt agccagtcgg tagaatcctg
    48481 taaatcactt gcagaataca gcttttcaaa agcttttgca aatgcttctt tgacttcttt
    48541 tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc attgtagcag gatccactgc
    48601 aggatagcca tttgtaccaa agtcttcttt taaagcagat tgataaaatc gcttcatgac
    48661 ttgcccgcgt ttttcctgat taccgttgac acttaagtac atcataacag aaatcccatt
    48721 tttgatccga cgctgagcga taccggcaaa ttttttgcca tggatgctta aatcataagt
    48781 tccaggacaa taagaatggg tgatttcgaa tgcttgtatc ggtgcctttg gaaaagcgta
    48841 tttagtcaat aggagcattt gctcgtaagc gtcatctatg gttatttttt ttgtgtcact
    48901 ttgggggaaa atcaaagaaa tattcaaaat tccttcatct gatacgatcc ctaatccacc
    48961 tgaatttctg atcactggag cgtaacctgc atctttcagt gtttggatcc cgtcacttag
    49021 aaaaggagtt cgaacatcct tcatacctaa gatgactgtg cagtcatatt gccagaaatg
    49081 taaaaagatt tgctggtgtt ctttagaata ttccgttaat atatctgtta atgcaaaagg
    49141 ggaaaagtcg tttttttgat aaatgtgctg atctagtcga atcgcagggt tcattcaacc
    49201 ggctcctttg tataaattca tattttctac aatattatac tctaaaatca aagagttgtt
    49261 ttggaaaaaa ggttttctgt aaaaatggac aagttggttg acaaaacaaa agaaactagg
    49321 aacaatgtag ctatgagaag taaaggagaa tgaataatgg aattatcaca aggaacaccg
    49381 atttcaatca aattgcgtac aaaagtaaaa cagcaagggg aagtgcaaga tttttatttt
    49441 gatttgaaag ggcaaatggt gacaattggc gatacgctgt acatacgtta taaagagatt
    49501 caggaggaga cgggcgatga gattcctgta acgatcaaat tagttccaga tggtcatgta
    49561 cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat ttggctataa agaacggtta
    49621 gaaacatcct atcgaacacc atacggtatg atccagattg ctacttttac gaaagaactg
    49681 catgttagtt tgaaagaccg tcccacagca gggaaggttc gaatcgatta tgatctgttc
    49741 atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg attttacagc gtaaatataa
    49801 aagaaaagtt tgattttttg tgtctgattt tgtatgataa ggagtagact gtgaaaggac
    49861 gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca aaagcgaatt atcaatgatc
    49921 gaagtagcac acgcgatctt agaacaacgt ggcgatgtca tggatttttc tgatttagct
    49981 aaccagatcc aaaactatct tgggaaatca gacagtgaaa ttcgtgattc actcgcacaa
    50041 ttttatactg acttgaatat tgacggcagc tttatctcat taggggataa tcgttggggc
    50101 ttgcgttcat ggtatgctat cgattcgatc gatgaagaag taaaccatgg aatggacgaa
    50161 gaggatgaag atactccacg tcgccgtaaa cgcaagaaag tcaacgcctt tatcaatgat
    50221 gatgaagacg cgatcgatta caatgacgat gacccagaag atacagatct gacagaagaa
    50281 gatgacgatg atctgtttga tgacgatgat gatgaagatg aagaaatcgc tgcttataat
    50341 tctgacttgc aagaaatcgg agcagatgac ccgacagatg atgaagaaga cttgccagga
    50401 aatatcgaag aagatttaag tatcatagac gaagacgatg atgatgaaga ttatgaagag
    50461 gaagaatttt ctgactctga aaaagaataa acattatttt cttacgagag gttgtgacag
    50521 agacgatcag cctatcagaa taaggaggtg tgacacgatt tttgtcacac cttctttttt
    50581 gtatataaaa atcccaagta aatacataaa aaataaaaaa attgaaactt ttagcgcacc
    50641 ttgtacgtca tattaagtga ggcagaaagg agtggagaat gatttttact ggatataaga
    50701 aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg actcatcgaa actgattatc
    50761 aaaaaatgtt ccgtatcacg atgaattacg tacatgataa agaagaggcc ttagatgtga
    50821 tgcaagatag ttttcataaa gccctgaact attttgaaaa agaaaaagag atcgagcatt
    50881 ttagtgcatg gttttatcgg atattgatcc gcacggcatt agatagttgg cgcagacaaa
    50941 aaaggacgcc tgtggactta tttgaaattc aagatatccc ccaacagtta cctttagaaa
    51001 cttccgttgc agagctccat atgattttag ataaaataga cagtccggaa aaagagattc
    51061 tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat tgcgactatc ttggatatga
    51121 atgaaaacac agttaaaacg aaaatgtacc gctcattgaa tgctttacgt caaatcctag
    51181 aatgaaggag agaagagtgc catgtattcc caaaaagaaa atttaaaaaa actaaagaaa
    51241 acttataaag aacaagcaat tcccaaaggg cttaaagagg agatccgcca gcgttttatt
    51301 atcgaagagc aatcatttat aaaagcaaag cggagaaaga gacgtctcca agggttcgga
    51361 gtatctttgg ctatcgtaat gattacaaca agtagccttc tttttaatag tcaagttcga
    51421 agctttgcag aagatttacc catcttagga tcagtcattg aattgatctt aggcgaacgc
    51481 tttactgatc gatctgaaaa aatcgatatt caggtaccga agatcaatac acaaaatgag
    51541 aaagaaaata aaacaattca tggattaaat caaaaatact ttcgcgaagg acaagcagat
    51601 tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg atcattacca agttttggga
    51661 gattatcaga aaatcgtaga cgataaccgg tttctcgtga ttgaaaggca gatcacccaa
    51721 acagcagcag atagccatgt tgaaaaaaga tacgacacaa tcgacaagaa aaacagtgtc
    51781 cagctctcac ttccactttt attcaaagat gacacctatc tatctgtttt gacaaaagaa
    51841 gtcaaacggc agatggccga acaagtcaag gaagatccat ctaagtacta ttggactgag
    51901 caagatattc aagaagggac gatagaaaaa ccaacacttg ttacgcctac acgaagtttt
    51961 tatttgaaca aagagcatca attagttttg actttttctc aatacgaaat tgctcctggt
    52021 tatatgggta caccagaatt tgtcattcct aagtccgtga caaaaacgat tttggcatcg
    52081 gaagattatt tggatcatta gacgagaagt agttgcgact agcagtttca attttcaagt
    52141 aagtacaagt aaataataag aagagaaaaa gagaaagaag agatatagtg aaaagaaatt
    52201 atttagttat cagtattatt gctttatccg tgcttttgtt tttcgaaatt acttcggtgg
    52261 cctccttgat caccgaagta aaaggacaaa cacactcttc ggagcattcg tcacaatctt
    52321 tcaaacaatc agaacaatca accattaaaa gccaatcaac tgaaacagct aacgtcaaag
    52381 aagccattca agaatcagcg gaaaaggtac aaagtcagtc atcacaatca acacaagaca
    52441 gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc aatcagcttt gatgatggac
    52501 caggagcgac cacaacaccg cagcttctgc gaatcttaaa agaaaaaaac gtgcatgcca
    52561 cttttttcgt cttaggagaa aatacggcgc agcatcctga aatcgtgaag cagacagctg
    52621 aagcagggca cgagattggc aatcacacat acgatcatca gaatctggcc actctttctg
    52681 cccagtcgat gacggaggaa gtgacgaaag cagacactga gatcaaaaaa gtcactggca
    52741 aaacccccac ttttgttcgt ccgccctatg gttctgtcac gaatgtagga gcaacgatca
    52801 tccagcgacc gatcatcgaa tggtctgttg attcagaaga ttggaagaca agaaatcctg
    52861 atttgatttt gcagaagatc caagcaacag tatacgatgg ggcaattatt ttattccatg
    52921 atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat cgattatctg aaagagcaag
    52981 ggtatcgcat cacgacagtt ggggatttat tagggcatcc aacggctgtc gagaactatt
    53041 atggcagaaa cgatcatcgg ccagttcagt aagtgagaca agtatcttta ataaataaca
    53101 cattttaata agtagttgaa cacataacta ccttacttgc aaaggcttaa caatatctat
    53161 acaggtacaa caaaaaactg tccaccaatt ttctttggcg gacagttttc acttaaaaat
    53221 aaagaagcaa ctattcgtaa attatgctaa aatagcagta gaacgcgtcc tgagggaatc
    53281 gaacccccgt ctcaagaacc ggaatcttac gtgatatcca ctacactaag gacgcaagca
    53341 ctgggataat tgtaactaaa cagataaaaa attacaaggg gattggacaa aaaaatgaaa
    53401 tttgagcaaa atttttcaca aaaacagcag cagacacaga aactagccat gacgcaacag
    53461 ttgcaacagt ccatccaagt tttacaatat aacagtgagg agctgttggc attcgttgag
    53521 aatcaagcaa tggaaaatcc attggtggaa gttgttgagc cggaatggca gccagattac
    53581 ataaaagctt cttcatcttc ttatgaagga gaagagacaa attacctaaa tcagattcct
    53641 gatacaaaag ggtctttatt tgattcattg atcgaacaag tccatttgaa ttaccgagat
    53701 acttttttga ggaaaatcgt tctttatctt gtagaataca tcgatttgaa cggatttttg
    53761 acgattagtt tagaagaagc cggaaaagag attggagcta cgcctatcca aatgctcgat
    53821 gcgttgactc tgattcagca attagaacca gctggagtag gtgcacgtag tttgcaagaa
    53881 tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg aattagctta tatcgtgttg
    53941 gaagaatgtt ttgaggaact ggtggagcga aaatggaaag aaatcgcaca acgtttttct
    54001 gttgatctac atgctgttca gcagatattc gactatttac aaacgttgag tccaagccct
    54061 ggccggattt tcgaccgtag cagcgaattg tacattattc ctgatgtccg ggtattagtg
    54121 gacgacgata aaaatgtaca agttatctca aaccgaaaaa atcagccaaa tatacgcttt
    54181 caagagagtt acttcaaaca aatgtcacaa caagcagata aagaaactga aaattattta
    54241 aaagaacgga aacaggaatt cgaatggttg aagaaaacga tcctacaacg tggggataca
    54301 attttgcggg ttgctcaagt cattgtttcc cggcaaaaag ctttctttat cgacaaggaa
    54361 cgtccaatca agcctcttac gttaaaggaa gttgcaactg agatagatgt gcatgaatcc
    54421 acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag acttcggtgt atttgaatta
    54481 aaaaaatttt tcactacacg aattcctacg aatagtacag aacagacaga agacctttca
    54541 gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc aagaagacaa aaacaagccg
    54601 ttgtctgacc agaaattggt tgaattgctg aaaaaagatg agatagcgat ctcaagacga
    54661 acagtagcaa aatatcgtga tttattagga atcccgagtt catcaaaaag aaaacgttat
    54721 gataactaat cagtcaaaag actagaaaaa gtatttcact ttttctagtc tttttagttg
    54781 aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt tgagatttcc ctttattgat
    54841 gtgaaattcg aatagttaat ttcttttttt atcgtatatg ggtcgtttta agtctacatt
    54901 ggacgtaaag tgtccaacta aggagatcgc tatgctggat gaaataaaaa tgattgaatc
    54961 tgttgcacca gatattatcg aagtgttgca agaacgctat aaaattttac gaaatatcta
    55021 ttggatgcag ccgattggac gtcgaagttt atcggaaagt atggggatca cagaacgagt
    55081 attgcgaaca gaaacagatc ttttgaaaaa tctgaatttg atcgacacct caaaaagcgg
    55141 tatgacgctg acaactaagg gcgaagaagt ttatcaaagc cttgaaaact tcatggatca
    55201 gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa tattttggta accaacgctg
    55261 tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg gctgatgcat tcggcgaagc
    55321 gctgagcgaa gccctagacc gactacttcc agaaggcgag aatatcatcg ctgtgatggg
    55381 aggaactact atggctgtgg tagccgaaca attgtctaat ctggaaaata agaaacggca
    55441 taacctgttt gtccctgcaa gaggcgggat tggtgaagcg ataactgtac aggcaaattc
    55501 tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac cgtgcacttt atgttccgga
    55561 acaattaagt ctggcaactt acaattcttt actcaatgag ccatctatcc aagaagtctt
    55621 aaacttgatt agtgaagcga attgtgttat tcatagtatt gggcgtgcat tacacatggc
    55681 agcacgtcgt aagatgactg aaaaagaatt agtcatgctg aaacaagcaa atgctgttgc
    55741 ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc gtttataagg tccctagaat
    55801 cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc atggcaatcg cgggcggaaa
    55861 atcaaaagct aaagcaattc gagcttatat gaaaaatgca ccaaaacaaa cgtggctcat
    55921 cactgatgaa gctgctgcaa atgagatttt aaaaggggta accctttaaa ataaatattt
    55981 ttttgatttt cataaggagg aaatcttaaa tgacagttaa agtaggtatt aatggttttg
    56041 gacgtattgg acgtctagca ttccgtcgta tccaagatgt agatggaatc gaagtagtag
    56101 caatcaacga cttgacagat gctaaaatgt tggcacactt gttaaaatac gacacaactc
    56161 aaggacgttt caacggaaca gttgaagttc atgaaggttc attcaacgta aacggaaaag
    56221 aagttaaagt attagctaac cgcaacccag aagaattacc atggggcgaa ctaggcgtag
    56281 atatcgttct agaatgtact ggtttcttca cttctaaatc agcagctgaa aaacatttaa
    56341 cagctggtgc taaacgcgtt gttatctctg ctcctggcgg aaacgatgtt ccaacaatcg
    56401 tttataacac aaaccacgaa acattaactg gtaaagaaac agttatctca ggtgcttcat
    56461 gtactactaa ctgtttagct cctatggcta aaacattgaa cgacaaattt ggtgttgttg
    56521 aaggattaat gacaactatc cacgcttaca caggtgacca aatgactcta gacggacctc
    56581 atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc aaacatcgtt cctaactcaa
    56641 caggtgctgc taaagctatc ggtttagtaa ttcctgaatt gaacggtaaa ttagacggag
    56701 ctgctcaacg tgttcctgta ccaacaggtt cattaacaga attagtaaca gttcttgaaa
    56761 aagaagtaac tgttgacgaa atcaatgcag caatgaaaga agcttcaaac gaatcttacg
    56821 gatacaacac agacgaaatc gtttcttcag atatcgttgg tatgacttac ggttcattat
    56881 ttgatgctac acaaactaaa gtaatgacag ttggcgacaa acaattagtt aaaactgttg
    56941 cttggtacga caacgaaatg tcatacactg cacaattagt acgtacttta gaatacttcg
    57001 ctaacttata agatagacaa acgtacaagt gtaaattata gacatgtaca tttaaaagcg
    57061 gggaagcaat cgcgcttctt ccgctttttt tgataataag tttattcagg aggaaataaa
    57121 atggctaaga aaacagtgaa agatatcgat ttaaaagaca aaaaagttct tgtccgtgtt
    57181 gacttcaacg ttcctttgaa agacggcgtg atcactgacg acactcgtat caaagcagca
    57241 ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag caatcctttt ctctcacctt
    57301 ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt tagctccagt tgcaaaacgt
    57361 ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg aaactcgcgg agaacaatta
    57421 gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg tattcgaaaa tacacgattt
    57481 gaagatattg acggtaaaaa agaaagcaaa aatgatacag aactaggtaa atactgggct
    57541 tcattaggcg atgtatttgt taacgatgct ttcggtacag ctcaccgtgc acatgcttct
    57601 aacgtaggta tcgcttcaac tggtatccca acagttgctg gattcttgat ggaaaaagaa
    57661 atcaagttca tcggtgaagc agtagaagaa ccaaaacgac caatgattgc aatccttggt
    57721 ggcgcaaaag tttctgataa aatcggcgta atcgaaaact tgattcctaa agcagataaa
    57781 atcttgatcg gtggcggaat gacttacaca ttctacgaag caaaaggaat caagatcggt
    57841 aactctctag tagaagctga taaagtggaa ctagcaaaag aattaatcga aaaagcaggc
    57901 gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag aattttcaaa tgatgttgaa
    57961 acacaagtaa tcgaaggaga cattcctgat ggtttgatgg ctttagacat cggcccagca
    58021 tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa cagttgtttg gaacggacct
    58081 atgggtgtat ttgaaatgag taactttgct aaaggtacaa tcggtgtttg tgaagcaatc
    58141 gctaacttag aaggcgcaac aacaatcatc ggtggcggag actcagccgc agcagcagaa
    58201 caattaggat ttgctgacaa attcacacac atctcaacag gtggcggcgc aagcttggaa
    58261 ttgcttgaag gtaaagaatt accaggacta gcagcaatca acgataaata aacgaccaag
    58321 tttgctcaat tctgacgagt aatcgaacaa aaggtgaagg gagttttcat gactccctag
    58381 ccatttttca ataaattaag gagtgtgttc ctcaatgcgt aaacctatta tcgcaggtaa
    58441 ctggaaaatg aacaaaactg catcagaagc aaaagaattt gctgaagcag taaaaaacaa
    58501 aatcccttca aatgacaaag ttgattcagt catcggatct cctgcattat tcttacaaga
    58561 attaatgaca tcagctgaag gtacagaact aaaaatctca gcacaaaact gctactggga
    58621 aaactcaggt gcgttcactg gtgaaacttc accagcagct cttgctgatc taggtgttca
    58681 ttatgtgatc atcggacatt cagaacgtcg tgaatatttc catgaaacag acgaagacat
    58741 caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca ccaatcctat gctgtggcga
    58801 atctttagaa acctatgaag caggcaaaac tgctgaatgg atcgaaggac aaattacagc
    58861 tggtttagct gatctttcag ctgaacaggt gtcaaacatg gttattgctt atgaaccaat
    58921 ctgggcaatc ggtactggta aatcagctga cgcacaaatc gctgacgaaa tttgtggagt
    58981 tgtacgtcaa acagttgaaa aactttatgg aaaagaagta tcagaagcag ttcgtatcca
    59041 atacggcggt tctgtaaaac cagaaaatat tgctgaatac atggcaaaag aaaatgttga
    59101 cggtgcttta gtcggtggcg caagcttgca agcagattca ttcttgtcat tgttagacgc
    59161 tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa tgtttgcact aatgagcaaa
    59221 attaactaaa atcgtatatg agggaaatcc cttaggaaaa aacaaactca aaggagagac
    59281 aaaacatgtc aattattact gatgtttacg ctcgcgagat cttagactca cgtggtaacc
    59341 caacaatcga agtagaagta tacacagaaa gcggagcttt tggccgcgga atggttcctt
    59401 caggtgcttc aactggtgaa tacgaagcag ttgaattacg tgacggagac aaagctcgtt
    59461 atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa caacatcatt gctgaagcaa
    59521 tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa agctatgatc gctttagacg
    59581 gaactcctaa caaaggtaaa ttaggtgcga acgctatttt aggtgtttct atcgctgttg
    59641 cacgtgcagc tgctgactac ctagaagtac ctttatacca ctacctaggc ggattcaaca
    59701 caaaagtatt gccaacacca atgatgaaca tcatcaacgg cggatcacat gctgataact
    59761 caatcgactt ccaagaattc atgatcatgc ctgttggcgc tccaacattc aaagaagctc
    59821 tacgtatggg tgctgaagta ttccacgcat tagcttcaat cttgaaagct cgcggattag
    59881 caacttctgt tggtgacgaa ggtggatttg ctccaaacct tggttcaaac gaagaaggtt
    59941 ttgaagtaat catcgaagca atcgaaaaag ctggctatgt acctggtaaa gacgttgttc
    60001 ttgctatgga tgctgcttct tcagaattct acgacaaaga aaaaggtgtt tacgtactag
    60061 ctgattcagg cgaaggcgaa aaaacaactg acgaaatgat caaattctac gaagaattag
    60121 tttctaaata tccaatcatc tcaatcgaag acggattaga cgaaaacgac tgggacggat
    60181 tcaagaaatt aactgacgta ttaggcgaca aagttcaatt agttggtgac gacttgttcg
    60241 taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg aattgctaac tcaatcctta
    60301 tcaaagtgaa ccaaatcggt acattaacag aaactttcga agctatcgaa atggctaaag
    60361 aagctggcta cacagcagtt gtatctcacc gttctggtga aacagaagat tcaacaatct
    60421 ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac tggttctcta tcacgtactg
    60481 accgtattgc taaatacaac caattactac gtatcgaaga ccaacttggt gaagttgcag
    60541 aatacaaagg tttgaaatct ttctacaact taaaaaacaa ataattcttt tctaatgaag
    60601 atacatgatc gactattgaa agatagtcga gtatgatcac ttagttaagt aatcgaactc
    60661 tctacttgct gaaatatcag caggtagaga gtttttttgc aactagcttc tgtatatgat
    60721 gtttacaaag aatggtacaa gaaaagatca tccttgaaaa aggaaagcta acaataacta
    60781 gcatcatata agagctttta aggatagaac agtagaatag gaatctatga gcaagtcctc
    60841 tcgtataaat aaaataggag ggaagtagca gcatattttt cataaagtgg ctctctttct
    60901 tcatttttac tttggttgct cctatttgaa aattcgagca cactcaaata caataaaaag
    60961 aaatggcaag ggagaggatt agatgaaaaa agaagaaaaa atcgcgattt tacaagagat
    61021 catccgaatt aaatcagtga atggaaacga aggtgaagta gcagcctatt tgaataagct
    61081 tttggcaaag catgacataa caggagagat tgtttcttac agagatggta gagataattt
    61141 gattgctcgt taccaaaagg gccaatcagg aaaagtgtta ggcctatctg ggcatatgga
    61201 tgtcgtggcg gctggtgatg aatcgtcttg gacctatgca ccctttgcag cagaaatcca
    61261 tgggaaccgt ttgtacggac gtggtgctac agatatgaag agtggcttgg cagcaatggt
    61321 gattgccatg atcgaactga aagagtcagg aaaaccattt aacggaacag tcaaattatt
    61381 agccactgtc ggagaagaag tgggtgaact aggtggggaa cagctcacga aagcaggcta
    61441 tgtagatgac ttagatgcct tgatcatcgg agagccaacc aattacagtt tgatgtatac
    61501 gcacatggga tcaatcaact atacagtcac ctcgcacgga aaagaagcgc atagctctat
    61561 gccagaccaa ggttataatg caatcaatca cctaaatgaa ttcattacga aagcaaatgc
    61621 tgaaatgaat cacctcgctg aaacaatcga gaatcctgtc ctaggaaaaa caatccataa
    61681 tgttacattg atcagtggcg ggaatcaagt caacagcatc ccaagccatg cgcagctcca
    61741 agggaacatt cgatcgattc cagaataccc aaatgataaa atcattgcat tgctgcaatc
    61801 aatcgtcaat gaattgaatc aagagacaga ctatcatttg gaattgatga tcgattacaa
    61861 caaaatacct gtcaaagctg atccagattc tcctttgatt cattgcattc agcaacaatt
    61921 cagccagcca ttacctttag ttggagcggc agcaacaacg gatgcagccg aatttacgaa
    61981 agctaaccat tccttcgact ttgtcgtctt tgggcctggt gtcgttactt tgcctcatca
    62041 agtagatgag tatgttgaaa tcgataatta tttggatatg atcgaaaaat atcaaggaat
    62101 tattttatcc tacttagcgt aagatttttt taataaatga aaaaacagag ccagattagc
    62161 attatt
//
LOCUS       DADVXV010000006        60425 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.006, whole genome shotgun sequence.
ACCESSION   DADVXV010000006 DADVXV010000000
VERSION     DADVXV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 60425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.006"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..1420)
                     /locus_tag="KB969_000330"
     CDS             complement(<1..1420)
                     /locus_tag="KB969_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBB6868345.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAG"
     gene            1672..2853
                     /locus_tag="KB969_000331"
     CDS             1672..2853
                     /locus_tag="KB969_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6868346.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            complement(2913..4541)
                     /gene="treC"
                     /locus_tag="KB969_000332"
     CDS             complement(2913..4541)
                     /gene="treC"
                     /locus_tag="KB969_000332"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBB6868347.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(4992..7703)
                     /locus_tag="KB969_000333"
     CDS             complement(4992..7703)
                     /locus_tag="KB969_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868348.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            complement(7713..8414)
                     /locus_tag="KB969_000334"
     CDS             complement(7713..8414)
                     /locus_tag="KB969_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868349.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            8600..9199
                     /locus_tag="KB969_000335"
     CDS             8600..9199
                     /locus_tag="KB969_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6868350.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            9280..10293
                     /locus_tag="KB969_000336"
     CDS             9280..10293
                     /locus_tag="KB969_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6868351.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            10401..11318
                     /gene="rbsK"
                     /locus_tag="KB969_000337"
     CDS             10401..11318
                     /gene="rbsK"
                     /locus_tag="KB969_000337"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBB6868352.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            11346..11741
                     /gene="rbsD"
                     /locus_tag="KB969_000338"
     CDS             11346..11741
                     /gene="rbsD"
                     /locus_tag="KB969_000338"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBB6868353.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            11741..13114
                     /locus_tag="KB969_000339"
     CDS             11741..13114
                     /locus_tag="KB969_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6868354.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            13471..15615
                     /locus_tag="KB969_000340"
     CDS             13471..15615
                     /locus_tag="KB969_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6868355.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLRLDKSFWLDLPLKK"
     gene            complement(15667..16707)
                     /locus_tag="KB969_000341"
     CDS             complement(15667..16707)
                     /locus_tag="KB969_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6868356.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(16984..18786)
                     /locus_tag="KB969_000342"
     CDS             complement(16984..18786)
                     /locus_tag="KB969_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868357.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(18800..19552)
                     /locus_tag="KB969_000343"
     CDS             complement(18800..19552)
                     /locus_tag="KB969_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868358.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(19561..19923)
                     /locus_tag="KB969_000344"
     CDS             complement(19561..19923)
                     /locus_tag="KB969_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6868359.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(20099..20971)
                     /locus_tag="KB969_000345"
     CDS             complement(20099..20971)
                     /locus_tag="KB969_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6868360.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(21022..21510)
                     /locus_tag="KB969_000346"
     CDS             complement(21022..21510)
                     /locus_tag="KB969_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6868361.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(21648..22439)
                     /locus_tag="KB969_000347"
     CDS             complement(21648..22439)
                     /locus_tag="KB969_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBB6868362.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(22494..23102)
                     /locus_tag="KB969_000348"
     CDS             complement(22494..23102)
                     /locus_tag="KB969_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBB6868363.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(23095..23412)
                     /locus_tag="KB969_000349"
     CDS             complement(23095..23412)
                     /locus_tag="KB969_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6868364.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(23568..24296)
                     /locus_tag="KB969_000350"
     CDS             complement(23568..24296)
                     /locus_tag="KB969_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBB6868365.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            24455..25336
                     /locus_tag="KB969_000351"
     CDS             24455..25336
                     /locus_tag="KB969_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6868366.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(25573..26616)
                     /locus_tag="KB969_000352"
     CDS             complement(25573..26616)
                     /locus_tag="KB969_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6868367.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26619..27287)
                     /locus_tag="KB969_000353"
     CDS             complement(26619..27287)
                     /locus_tag="KB969_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6868368.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            27429..29765
                     /locus_tag="KB969_000354"
     CDS             27429..29765
                     /locus_tag="KB969_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6868369.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(29880..30191)
                     /locus_tag="KB969_000355"
     CDS             complement(29880..30191)
                     /locus_tag="KB969_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868370.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            30372..31847
                     /locus_tag="KB969_000356"
     CDS             30372..31847
                     /locus_tag="KB969_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBB6868371.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            31894..32478
                     /locus_tag="KB969_000357"
     CDS             31894..32478
                     /locus_tag="KB969_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBB6868372.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            32480..32863
                     /locus_tag="KB969_000358"
     CDS             32480..32863
                     /locus_tag="KB969_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBB6868373.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(33180..33464)
                     /locus_tag="KB969_000359"
     CDS             complement(33180..33464)
                     /locus_tag="KB969_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBB6868374.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(33816..34526)
                     /locus_tag="KB969_000360"
     CDS             complement(33816..34526)
                     /locus_tag="KB969_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBB6868375.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(34523..35995)
                     /locus_tag="KB969_000361"
     CDS             complement(34523..35995)
                     /locus_tag="KB969_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6868376.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            36133..36606
                     /locus_tag="KB969_000362"
     CDS             36133..36606
                     /locus_tag="KB969_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6868377.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(36759..37310)
                     /locus_tag="KB969_000363"
     CDS             complement(36759..37310)
                     /locus_tag="KB969_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6868378.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            37415..37945
                     /locus_tag="KB969_000364"
     CDS             37415..37945
                     /locus_tag="KB969_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBB6868379.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(38428..38871)
                     /locus_tag="KB969_000365"
     CDS             complement(38428..38871)
                     /locus_tag="KB969_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868380.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(38887..40047)
                     /locus_tag="KB969_000366"
     CDS             complement(38887..40047)
                     /locus_tag="KB969_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6868381.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            40554..42254
                     /locus_tag="KB969_000367"
     CDS             40554..42254
                     /locus_tag="KB969_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868382.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(42356..43189)
                     /locus_tag="KB969_000368"
     CDS             complement(42356..43189)
                     /locus_tag="KB969_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBB6868383.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(43493..45658)
                     /locus_tag="KB969_000369"
     CDS             complement(43493..45658)
                     /locus_tag="KB969_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6868384.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            45918..48212
                     /locus_tag="KB969_000370"
     CDS             45918..48212
                     /locus_tag="KB969_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6868385.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            48205..48870
                     /gene="pgmB"
                     /locus_tag="KB969_000371"
     CDS             48205..48870
                     /gene="pgmB"
                     /locus_tag="KB969_000371"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6868386.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            48863..49870
                     /locus_tag="KB969_000372"
     CDS             48863..49870
                     /locus_tag="KB969_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6868387.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            49892..50911
                     /locus_tag="KB969_000373"
     CDS             49892..50911
                     /locus_tag="KB969_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6868388.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(51192..52559)
                     /gene="nhaC"
                     /locus_tag="KB969_000374"
     CDS             complement(51192..52559)
                     /gene="nhaC"
                     /locus_tag="KB969_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBB6868389.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(52668..54089)
                     /locus_tag="KB969_000375"
     CDS             complement(52668..54089)
                     /locus_tag="KB969_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6868390.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(54332..56209)
                     /gene="tdc"
                     /locus_tag="KB969_000376"
     CDS             complement(54332..56209)
                     /gene="tdc"
                     /locus_tag="KB969_000376"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBB6868391.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(56500..57756)
                     /locus_tag="KB969_000377"
     CDS             complement(56500..57756)
                     /locus_tag="KB969_000377"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBB6868392.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(57868..58073)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            58336..59637
                     /locus_tag="KB969_000378"
     CDS             58336..59637
                     /locus_tag="KB969_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBB6868393.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(59706..60305)
                     /locus_tag="KB969_000379"
     CDS             complement(59706..60305)
                     /locus_tag="KB969_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6868394.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT        18243 a        12359 c        10828 g        18995 t
ORIGIN      
        1 ttcctgcata taaatgaaaa tgttcggagt cagccggtgc aatcgtgtga tcactgaatt
       61 gaatatatct aaaagcgcca ctttccttat cttctgcttc gaatagatac cttacgccac
      121 ggtttcctgc ctcgtaggtc aagatttctt tccctacata acgataattt gaacgtttcg
      181 ttgttccatt cttaaacgta aatgccatct ctttctcact gatcttgatt gaagcaatat
      241 ctgtttgata gcccttcgta taatattctt tatattcttg tgctgtctta tcctgattca
      301 atttttcttt atattcaaaa acaggatcaa aagtcccatc ttctacatac gtatctactg
      361 tttgccaagt tcctgcccaa tctgaaagag agcgatcttg tacatcctcg tcttcaaaat
      421 aaccgttgta gacgctcttt tcttttttgg gggtcaaagt atcttctagc gggttttctg
      481 tctctgtcgt ttttttcaac gcttcgaggt ttgcttccat gatagaaaga tagttttctc
      541 cattttctat ttgttcattc gtcaatcctt ccaaaggatt caatacttct aaagatacac
      601 ctgcttcgtt tgctaacgtt ctggcaatac tatctttggc gttttcttca aaataaatat
      661 agttgattcc atgttcttta acaaagtgtt tcagttcagc aattctcgcc gcagacggtt
      721 cttcactaga agaaagacca gcaatcgata cttgattcaa tccatattct aacgctagat
      781 agttgaatgc agcatgttgc gtgacaaaag atctttgttt tgcttgctta aaggtttctt
      841 gataaagctg atggagtgct tgaagtttct cggtataggc tgctgcattt tttgtccata
      901 cttcctgttt ttctgggtaa gcttcaatca gctgatcacg tatgtttgct acctgcttga
      961 ttgctaaact tggagctagc catacatgtg ggtctagctc atgtgtatgg ccttcttccc
     1021 cgtgttcatg gtcatgatca tgtccttctt cacttcccgg aagtaaaagc ataccttctg
     1081 tcgcttttat cgtatggaca ttgccttctt gtaatgtttt ttggattgcg gggacccatg
     1141 tttccatgtt ttcatcatta taaacaaaga tatctgtatc ttggatcttt gccatgtctt
     1201 tagcagaagg ttcataatcg tgggaatcag tccctgctgg aatcaataac tctacttctc
     1261 cttcatcccc gacgattgct tttgtaaaat catacatggg ataaaaggtc gtcatcacgc
     1321 tcaatttttc tttactgtcc tcggctttcc cacttgcccc gcaagcagtt aacatacctg
     1381 ctaaaaccag catggccaat atacctatca atcgtttcat ttatgacact cctcttctca
     1441 tcttctttca tttgaatgtt ccgattcgct tttcgcaaac cgtaatagtt acgttttagc
     1501 aacaggattt aatttatcat atggttaaaa gaactgtcaa gcgttttctt attttaattg
     1561 atgagaaagt ttatatgaat gattgacgat atttttgcaa tcaacctcta tcattttcct
     1621 tttatacccg cttttgtcta taatgaagtt atagataaag gaggaaaaag agtgaaaaaa
     1681 gaaacagata caacgaatcg tttgatccgc tttttaggag gaaaaacctc ttactatgtt
     1741 ttaggaatag ttatcttact tgcgctgatc atttattttt tccatcagat ctcgtttata
     1801 ttcaagcctg tcggaatcat tatcgctact atcttgcccc cattattgtt tgcactgatc
     1861 ttgtattatc ttttggaacc agtcatcaaa cgtttgagca agcacctttc gaggaacttg
     1921 tcagtcatta tcgtttatgt gattatttta tttttattgg ggcttggaag catatggctt
     1981 attccttttc ttgaagaaca ggcaaagaca ttgatcagta gtttgccaga tttgtttcaa
     2041 gattttcaag agagtctccg acaatttttg gagaaaacac cttttgccga ttcatttaat
     2101 caatttttcg cttctattga cgacgtgacg tctgatatag ctggatttat tggaaattat
     2161 tgggaaagtg gcgcacaacg gatcagcaac attttttcaa ctgttacagc tatttttatt
     2221 actttattta ctggtccaat tgtcgctttt ttccttttga gagatcctca aaaattttat
     2281 cagtcagttt tagcgattgt cccaccagca tttcgtacag attttaaaaa tttgacaaag
     2341 attgctaatc aacaattggg ttcatttcta aaggggcaaa tcattgcttc atttatcctt
     2401 ggagcagtct actgggtttg tttcttactg atcggattag aatttgctag tgttttagct
     2461 atttctgctg ggttgttatg tatcattcca tatattgggc cgtttatcgc cttctttcca
     2521 ggtttgatca ttgcattcca agactctact tttatggctg tcaaatttgt cattgtctgg
     2581 tttgccgtac aacttctcca cggtgacttg gtgattcctc gagtaatggg tgatcgttta
     2641 cagatccatc cgattacgat cttaatcgtt ttacttgtca tgggtgatct aatgggaatt
     2701 gtgggcgtta tttttggtat tcctatctat acgttagtca aattactcgt tacttttatt
     2761 ttccgtaaat tcaaacaacg ctacaataaa ttttatggcg ataaaggaga gtatgaaaac
     2821 tcttcatttt ctgaagaaga ttattttaaa taaaacacaa aacgtcgatc ttacgagaat
     2881 agctcgtagg aacgacgttt tgtgtttttg ttttaatttt tcagcaaagc aattgcctgg
     2941 tatggtttta gctccagact ttgatgaaga acagtatcgg aataattatc gataagaata
     3001 ttggcttctg tgaatccttc tgggatggcg atccttgtat ctttatcata gaaatttgtt
     3061 aatacaagca gctgctgtcc ttcaaattgg cgaagaaagc cataaacttc cggatgattt
     3121 gcttcataag catgataatc tccttgtgca acgattggat atgtttttct cagccgaatc
     3181 aatttcttgt aataggacaa aatagaatct tcagaagata gttctttttc tacattaatc
     3241 tcttctagct tgcctccaac ttttaaccaa ggtttccctg tagtaaatcc tgcttgttct
     3301 gtgtctgacc attgcatggg tgttcgagag ttatcgcgag attttgcttt gatccgacga
     3361 aacgcttctt tttctgtgaa tccttgttca aggagtaact tataagcatt caaactttct
     3421 acgtcaatat agtcggaaat cgatgaatag tctgggtcga tcatgccgat ttcttctccc
     3481 atataaatat agggcgtccc acggttcaaa tggatcatgg ttgctagcat ctctgctcct
     3541 tgttttcgat actgatcgat agctacaaat cgattgagcg cacgtggctg atcatgatta
     3601 ttaaaaaata gagcattcca gccgttaccc tcactcatct tttctcccca tgtatgaaat
     3661 agtcgcttta attctgcaaa atcaaatgga ggagtagacc atttattccc attttcataa
     3721 tcgactttca aatgatggaa attaaagacc attgataatt cttctctact aggttctgta
     3781 tacaagatac aattttcgat cgtcgtagag ctcatttcac cgactgtgat gatagtggaa
     3841 tccgtcccaa acgttgcttg gttcaattct tttagatacg tatgggtgat tggtttgtcc
     3901 gtatattcag gtttgccatc attttcttta ttatttttca attgttcgtc tttaccgata
     3961 acattgataa catcgaaacg gaatcctttt accccttttt ccatccaaaa acgaacaact
     4021 ttgaatagtt cctctcttac tgcttggttc cgccagttca agtcagcttg tgtccgatca
     4081 tataagtgca aataatattt ccccgtatct ccaaatggcg accaagcact tccaccaaat
     4141 tttgataccc aatccgttgg ctcttctctt aaaatgaaga agtcctgata atgctggtcc
     4201 cctgctagtg cttttttgaa ccattcatgt tctgtcgaaa cgtgattcag caccatatcg
     4261 agcatgattt ctatccggta tttctttgct tcggctatta gctgttcgaa ttcctccatc
     4321 gtaccaaaga taggatcgat ggctgtgtaa tcagagatat cataaccgtt gtctttttga
     4381 gggcttggat aaatagggtt tagccaaatc atgtcgatgc ctagatcatt cagatacggg
     4441 agtttttctt tgattccttt taaatctcca attccatcac cattactgtc tttgtaagat
     4501 ttgggataga tttggtaaat gactttgtct ttaaatgtca tggatattta cctccattca
     4561 actgatttat tacctaccac aacttatata tacaagttat catttattat tataactgaa
     4621 ccgaaagcgt ttgtaaaatt tatctttata cattctaaga ggtctgttgc ccaataaaaa
     4681 acaagagatc agacatgtat ttgtctatcc tcttgtttaa aatagcaaaa tattcttgtt
     4741 tcttctataa atggtgttca aaagctttta tctacggcaa tcagtcttct caaatgtaaa
     4801 acatgaggag ctaattttat ttgagtattc tttttgctcg atgcaggacg gcttttttac
     4861 aacctctgat tcatggtgtt caatcagctg tccttcggta ttagctcaaa aaacggcaaa
     4921 atatgaaaaa ctattttgcc gtttgtttct ctaatactca ggtcaaaccg ctgatttcac
     4981 aacctctgtt tttattcatt cgatttcaac gcatcaatca tatcgatatg ctttaatttg
     5041 aaatgggtaa caatcatcac aataaccgta aatacgatag ttaatcctgc tgataagaca
     5101 taagcccacc atgtgatcac taatggaaag atgacattct ccatagacgc ttgttgcaag
     5161 atgaagtcag tcaatatata tcctacacca aatcctccga tgattcctaa aagagtaaag
     5221 atgatatttt ctcgaacaat gtacatcgtg acttctttat caaaaaatcc aaggactttt
     5281 attgtagata attcgcgtac acgctcggaa atattgatat tagttagatt atacaagacg
     5341 ataaaagcca gcagtcctga taatacgaca aagattaaga caaccgagtc taagttcgcc
     5401 attgattctt cttgcgtttc gatttgtttg gacatgaaag acgtatttgt cacagcgtct
     5461 gtggcaagca gtttctcgga aagcatttct tcttcttttg ttgtcatctt atctgtacgc
     5521 agcaaaaatg cattatccat catcgattga tcagtaactg aagcataata ttcaggggac
     5581 atataaataa agctacctag atagtttttc acgatttctt ttacttcgac tttccattct
     5641 ttttgatctt catcataaag cgaaatatga tctcctgtag ataagtcaaa tagttctgct
     5701 actttttgcg taatagcgat tcctgtttta ggcaaggagc gtgggttctc ttcaagatca
     5761 gttaaatgga taaaacgatc caaatcagct gttttacttg gtacgatcac tgtcagactt
     5821 tgcgaagcat gtcctttttt tctcaattct acggtttgag tatgaatagc taggatctca
     5881 tttacttttt cttgcttctg cagcatatcc gctgcttttt gacgactatc ttccgtggat
     5941 gaatccaatg taacgattgc ttgatagtca atgatcggtc caaattgttt ggctgaaaca
     6001 gaacttagag aatctttcaa tcccacgcct gcaaccatca gcccggcaca tccagcaatt
     6061 ccgataatcg ccataagcat tcttgactta tatcggaaga gatttcggta actgattttt
     6121 tgattaaagc taaggcgtga ccacagcgga gtgatgtatt caagaaaaat gcgtttccct
     6181 ggcttcggtg ctttcggttg aagcaatgca gcaggccgtt ctcttaaatc tttgaataaa
     6241 acgatcattg cagcgccaaa tgcggcaatg aagaatgcgg cagctgcttg taaaatcggc
     6301 ggccagtcat aaaaaataag cgcactccca atatcatacc gctcgttaga cagctcaaaa
     6361 atgatccttg gcaaaagatt cgttcctaat atcgttccta aaacaatacc tatccctgag
     6421 gctagacttg catagattgc atattttttt gcgatttcaa ctttcgtata acctaacgcc
     6481 tttaatgtcc cgatttccct gcggttttct tctaccatac gtgtcattgt cgtaaaggtg
     6541 atcaatgcgg caataaagaa aaagaaaaca ggaaaaacat tggcaatcgc agcgatacga
     6601 tcagacagat caccaaattc ttgaaaaccg acattttctg aacgttcatt gtataggtat
     6661 gatggtttag ttaaattttc aattttttct gcatttcgat tcaattcttc ctctgcagag
     6721 gccagttcac gttctttctc aactaattgc ctttcttgtt cagcaagttg agcttcttgt
     6781 tgagataatg tttgaacagc gattgttcgt tgcgcttcag gaagctgctg gatagttgct
     6841 gactgttgcg ctaactgttt tttagcatct tctaaccgtg ttcttgcttg cgttgtttgt
     6901 gctttgccat ccgctatttt ttgctgtgcc ggttctaatt cttcgttggc cgattttttc
     6961 agctcttcta agcgttcttc gggtcgatct tgtaaatact tttctgcctt ttcttgattt
     7021 tgctccattt tatctttgta agctttgctg tacgtattca aattctttac gtttgtaaaa
     7081 tcaagatata agacagaata aatatctgtt ttaaaaacgg attcaggtaa atagacaaaa
     7141 taatcgacgc taccatttcc gacgttcgcg tatcctctct ccaaattgtt gatgaacaat
     7201 ggagaacgga caaagcccgt gatggtatac tctttttctt tcaattcatc tgaatcaatc
     7261 tgataaatat caccgatttt atacccttca tcttccgctt tttcatccaa tacaagctgg
     7321 tttggttttt ccgggagttt tccatcagtt aattgtagct tgttctgctt gttatttttg
     7381 ttataagaaa atatttgaat cacttcgttt ttgccagtat tggaataata gatctgtttt
     7441 cctgtttcta cttttgcatc tgggatcttt tctgcttgag caatatcttt ttgtgtcaag
     7501 ccaccagtag aaacgatttg caaatcagaa agtcctgctg taccaacata gtgatccatc
     7561 gttttttgca tgacaggtcc agcagttttg acacctacaa ataaaagtgt tcctagcatg
     7621 acaataagga tgattgcaat gaatcgtcct ttagattgcc gaatttcgcg aaaacctgct
     7681 ttaagatatg ttcttgtttt cataaaatcc ccctaccata caatctcatc aatggatgaa
     7741 ggatgatcat ttaattcaac agaccttact ttagcatcat taatgtgaat gactctatca
     7801 gcgatgggcg ctaaagcaga attatgtgta atgatcaaaa cggtattgcc gtgttgtctg
     7861 ctagcgtttt gcaataattt caatacttgc ttgcccgttt caaaatccag cgcgcctgtc
     7921 ggttcatcac ataaaagaag tttgggattt ttagctagtg cacgagcaat tgaaaccctc
     7981 tgctgttcgc ctcctgataa ttgggacgga aagttattca atcgatgagc taggcccact
     8041 tgcctcaata cctctacagg atcaagcgca tcaggagaaa cttccgttgc caattccaca
     8101 ttttcttttg ctgttagatt aggaacgaga ttgtagaatt ggaaaacgaa ccctacatct
     8161 gttcgtcggt aagcagtaag ctgtttatct gaaaattgcg caatatctgt gtcatcaata
     8221 atgatctgac cttcatcagg tgtatccatc ccacctaaaa tattaagaat cgttgacttt
     8281 cctgctccac ttggaccaag tataatcact aattcgcctt tttcaattga aaaagaaata
     8341 tcgtcatttg ctgtaatggt cgtttctccc attttgtatc gtttgtattc attttttact
     8401 tcgacatact tcactctgat tcctccattt tcacgatatt tctcgctata tctatgcatc
     8461 gaatgcgttt tctcacactt atttatttta ccactgaatt tctctagact aaagaaagga
     8521 atcctttaat ttagttgaca aataaacgat ttatgattta cttacataaa aaacattgtt
     8581 atttgaaaga aggaacatca tgaatgattt aaaggaaaat atgatttttg atttatcaaa
     8641 aactgctttt gtcgcgatcg acatgcaaaa agagatcgta aataacggta cactctctcc
     8701 acacactgca gcatctattc tgacaaacaa tgatttgtta gtaagaacat tgaaacgtac
     8761 cgctgccttg aaagttttag tgaacgtaga catctccact ttcccttatt tgagtcaaca
     8821 aactgatatg ggtggaatga ctgcttctgt acctccagaa ttcactgatt tacttttgaa
     8881 ggattctttg aaagatacag ataatatgtt gactatcaca aaatacaatc caagtgcttt
     8941 ttttggtact tctcttgatc ttcaacttcg ccggcgtgga atcgaaacta tcattttaag
     9001 cggtgtagcg acaacaaacg gtgtatatgc tactgcatta gatgcctttc aacacgggta
     9061 ccatatcgtg cttgctgaag atgcttgcag tgatcgtgac aaagaatccc atcaattgtt
     9121 cataaaaaag atatttccga aaactgcacg agtacgctca acgaaacaaa taatcgaagc
     9181 tatccaacaa agcaaataag tactggcaca cgtgattttc atttacttct ttttgatttc
     9241 atgggaaaat aaccacagga tttagatagg agtatgaaca tggtgaaaaa aaagatcaca
     9301 atcaaagaag tcgctaaact ttccggcgtt tcaatcacaa ctgtctcctt gatattaaat
     9361 ggaaatacgg agaaattcag tccgaaaact gttcagaaag ttttagctgc caaagaagaa
     9421 ttaggctatc agcctgacta ttttgctaga caaatgatta ccaaggaaac gaaaacaatt
     9481 ggtgtactcg ttcctgatat cacgaatcca ttcttcagta cactgatgcg aggaattgag
     9541 gatatcttgt ataagcagaa tttcgtcacg atattatgta atgctgattc tgatcatcaa
     9601 aaagaaatcg aatatctagc cgagctcaca cgtcgaggtg tggatggatt cattatcgcg
     9661 acttctgctg tctctacaga tgcaatcaac gaaaatttga aaaaacaagg ccggcccttc
     9721 attgttttgg atcagaaaaa atctgaagga tttagtgatg ccgtacgaac agacgatttt
     9781 cgcggtggtt acctagcggg catgcacttg cttagtctag gacatcaaac gatcgccctt
     9841 gtctatcctg aaaatccacc ggaaaatgtc cacgctcgga ttgaggggtt taaatctgct
     9901 cttgatgttt accaaatccc tcacgaccaa ctgatcctct tacctacaca gttctcaaaa
     9961 caaggtggct accagatcac agcagaactt cttgattctg ctgcaactgg tgtgtttgct
    10021 ttaaatgatg aattagcttt tggattatat cgcggattag aggaagctgg aaaaagcatc
    10081 cctgaagact acagcattat tggctatgat aatatagata tgtgcgagta tatcaagccg
    10141 aaactgacaa cgatcgcaca accaatcttc gaattgggac aaacatctgc caagttattg
    10201 ttagatcgga tccaattccc agaaaaagaa tgggaagaaa aaagattacc tgtacgatta
    10261 gaaaaaagat tttcaactgc acccttgaaa tagctttcaa ggtgtgctat atttttatcg
    10321 aactattaaa acgttttact aaaacgtttt aaaaaataat tttcccatca aaataaatga
    10381 gatagttgga ggtttgtaaa atgaacacgg ttacagtaat tggaagtatt aatatggaca
    10441 ctacccttcg tttaaccaac atgcccaagc caggcgaaac gatgcatgcg catgagattt
    10501 ttcacgctgg cggaggtaaa ggtgccaacc aagcagtggc agccaaacgt tcaggcgcac
    10561 ggacatcttt tattggaggc gttggggctg acagcgaagg acaacagtta ttagatctac
    10621 tgacaaaaga aaacatcgat acatctggga tagctgaaat ccaaggcgcc acaaccggac
    10681 aagcaatgat tatggtagac gcagcaggag aaaatagtat cttgatccat gcaggggcaa
    10741 ataatgcttt ccatgaacaa gaagtcctaa aaaacaagca actgattaca aacagtgact
    10801 ttattattgc tcagtttgaa agtagcttag atgcgacgat cctagctttt tctattgcaa
    10861 aagacgcagg aaaaacaacg atcctgaatc ctgcaccagc tcgtgaaacg attcctactg
    10921 aactacttga aaagacagat atcattatac caaatgaaac agaaacagaa atcattacag
    10981 gaatcagagt gacagatcat aacagtttgg tcgcagcagc cgaaaaactc catgaattag
    11041 gtattggaac agtaatcatt acactaggca gtgccggcgc tttctatcat acagaaaaag
    11101 aacacggtat cgtccctgct tttaaagtgg atgccgttga cacaacagcc gcaggtgata
    11161 catttattgg cgcattaagc agcacacttc agccagacct tagtaacttg aaagaagcga
    11221 tcctttatgg aaatctagcc tcttctgttg ctgtgcagtc ttatggtgcg caaccttcta
    11281 tcccttaccg cgaagcttta gaacaatcag cagtctaaaa ttaacaatga gaggaagaaa
    11341 caaacatgaa aaaaggaaaa gtaatcaatt cagatatttc acgagtaatc gcacaaatgg
    11401 ggcactttga taaattaagt atcggggatg caggcatgcc tgtccccttt ggtactgaaa
    11461 aaatagattt ggctgtctca aacggtcttc caagtttttt atctgtttta gaaaacgttt
    11521 tagaagaact tgaggtacaa tcgattgaat tggcggaaga aataaagaca atgaacccgg
    11581 aaatattgga aaaaatcaaa ttattgttac cagatacacc gattagcttt atcccacatg
    11641 aagaaatgaa aaaagagttg aataactgtc atgcatttat tcgtacaggc gaaatgacac
    11701 cttacgccaa tattatatta gtgagtggag tggtcttcta atggaaacga caatgaatcc
    11761 tgaacagatg gtactgtccg agcagattca tatgctgatt gaacagttgg gaggaaaaga
    11821 caatattgat tctgtccttc catgtgcgac tcggcttcgt atcaaattga aaaaacagcc
    11881 agtagccaat gcagaaaaat taaaacagca aatcccttcc attaagtatt tcattttact
    11941 cgatagatat gcagaaataa tcatggatca gggattggct cctgcttaca aggaattgac
    12001 gcgtcaaatc gatcattcag ctccgaaaga aaagctaaat ccgatcgaaa aactatttgg
    12061 tttgatatcg gaaatcttta cgccgatcat tccgctgttt gccggttctg gtatattaaa
    12121 aggtctggtt gttttagcga ctacgattgg ctggcttagt gaaacaagcg gaacttatca
    12181 tattttgtct gctgcgtcga atgccgtctt ttattttctg ccaatctttc ttgctttttc
    12241 tgctgccaaa acgtttaaag tgaatggata tattgcggct gtcattgctg cagcactgat
    12301 tgaaccgaat ctgacctctt tactttcaga cagtggcaaa gcagctactg attttctggg
    12361 gattcctgta gtactgatgc agtatacgtc tactgtcatg ccggcgattt taggtatttt
    12421 cttttattct tttgttgaaa aattcctcaa aaaatatatt cgcgaaaata tgcaattagt
    12481 atttgtacct ttactttcat tagttatcac ggttcctttg acgttaatgg tattcgggcc
    12541 tgcgggtgtt taccttggcg aaggtttagc tgccgcaatt acttggatga tggatattaa
    12601 cggaccgatc agtggcgcaa tcatcgctgg tggttggaat attttggtaa tatttggtat
    12661 ccaatgggct gtaaaccctg tcatgatcag taatatctct gcttatgggt tcgaccgaat
    12721 cgttccgttg acaggagcag ccaattttgg aatggctggt gcagctttag gtgtatttct
    12781 gcgaagtaaa cgttcaaaaa cccgttcgat ctccggttct gcttttgctt cgattttact
    12841 tgcgggagtg accgaaccaa ctgtttacgg aattgcgatc ccattgaaaa aaccatttgt
    12901 tgctgcttgc attggtgcag ctgctggtgg agctgtaatg ggatttgccc aagtgaaagc
    12961 gatcgctttt gtatttggta gtctgaccac attgcctgca ttcatttccg gtactttttt
    13021 ctggtactta gcaggactgg ctgttagtct agtcgtagca atgatcacta ctctcgttag
    13081 cgggtttgat gaagacctaa tgtcttatga atagttaatg aaaaagactg aagtatgaga
    13141 tgtttatcac atatttcagt ctttttcttt ttaggatcat tatttttata aatttttgtg
    13201 atactttcca aactttggta taatttacat atgcataacc atttttatcc ccacttgttt
    13261 atccccaaac aaaggtggtc tatgcaataa aatgaacgtc aaagaaaaac gaatgaatgc
    13321 tcgttgctta tttacaaatt gttttattta gaatacacag acagatttat gaaaagaaaa
    13381 agcttttcga cacgattatc tgttccaaaa aatgtctaat gaatgctgaa taagacagaa
    13441 aatcaatgaa aggaaaagga ctagtttatt atgaaaaata aaaaaacgat acgtttgcta
    13501 gctgctactt ggctgattgc tccgtctgtt ttgtcgacca ataccgtatt tgccgtagat
    13561 aatcaaatag ctgatcaaac agtcacaaca gatacgacta catccagctc agctactagt
    13621 gaaacaacgg attcttttac agaagaccca actggaacaa ctaactcaac aacaggatcg
    13681 accgagccaa ctgaaattga tccggctgat ccatcagaaa atgaaaagcc agccgagaca
    13741 tattccctta caattgctcc ttctttgatt ggtaagatcc aactgactgc ttcgacagcg
    13801 gattcccctg aacagcaacc tttggatatt acggaaagtg gaacggtaga aggtttatta
    13861 gcggaaacga aggtaactta cactattacg ccagctgaag gtgaacaaat tgcttcagtc
    13921 gctgttaatg gtgccaaaga agtaaattat gatgcaaaga cctttacagt aggtacgaac
    13981 aatttatcta ttactgcaga atttaaagct ggaccggata cttcaacaga gaaaccaact
    14041 gatcctagtg aagaagtccc tagtacacca gatccggaaa cgccaaacaa accagatgtg
    14101 ggtaataaca acaataataa tggttcaaat aattcaaaca ataataacaa taattcgaac
    14161 agcgggaatt cttcgaatca aacaaaccca tctggatcga ataacaatgg aaatactcag
    14221 agagaaccaa accatccaaa caatggttca tcgaatggcg gaacgaacaa tgcttcatct
    14281 cgtccaaata cagcaaatca aagcggtata gagaatccat cttctgcttc ttctgatttt
    14341 gttgtaaaat caccaattga tgctgtattg cctacaaata caacgaatgt ccaacaagca
    14401 atcgttcgag aagcattcaa gcatcttgga aaaccatatg tatggggagc aaaaggtcca
    14461 aatacttttg actgttctgg tttgacttat tacgtatata tgaaagcaac cggtcattat
    14521 atcggtggct ggacaggcga acagcaatat gcaggtacgc agattccagt aagtcaggcc
    14581 caacctggcg acctcgtctt ctggggacct tcttccggtg ttactcacca tgtaggtatc
    14641 tatattggga acggacaatt tatccatgcg cctcaaccag gagataaagt tcgagtaact
    14701 tctatttcag atttcacgcc tgattttgct gtccgagtaa acttagcagg tttacctgct
    14761 gcttcaggtt cgctgacagg cggctcatct attttagatg gattagatgg ctcgttccat
    14821 ttcagtcaaa accaaacaac tgatcagttc ttgaaaaaga ttgcagatga tgcacaggaa
    14881 atcgggcaaa aagaaggaat ctacgcatca gtcatgatgg ctcaagctat ccttgaaagt
    14941 ggatctggaa acagcttatt atcaagcgaa ccaaatcata acctttttgg tatcaaagga
    15001 tcatataaag gaagcagcgt gaccttcaat acacttgaac aagatagttc cggacaaagc
    15061 taccaaatcc gcgcacaatt ccgtaaatat ccttcttaca aggaaagttt ggaagactat
    15121 gccgacttga tcaaaaatgg actgactggc aatcctgatt tctacaaacc aacttggaag
    15181 tcggaaacaa aagactacaa agaagcaacc aaatatttgg aaggacgtta tgctacagat
    15241 cgccaatatt cacaaaaatt gaacgcgatc atcgaagcgt acgacctgac aaaatatgat
    15301 gaaccgaaaa aagaagcagc aacaactgaa gaagcaaacg ctgaaatcct caatatgtct
    15361 aagcgattcg atgtgccaat caaatggaca acagatggcg tgccaatcac aggattagaa
    15421 ttttcaacga taaaacgcgt caacaacgct tcttccatct tccgtgtcgc ttcaatctgg
    15481 gatttgtgga acaattttac ggcaagacag ataccagaaa caactactcg tacagttaaa
    15541 gctgcaactg ttcctgtact aaccttgtta aggttagaca aatcattctg gcttgatctg
    15601 cctttaaaga aatagaataa attaaaaagg ggatgtgaca ctgtcacact ccctttttaa
    15661 tttattctat ttctttatat ttattttgta ttccgttaca aactcgcgta cttggttagg
    15721 ttccagagtg acatctccaa aactttcaag tcgctccgct cctggcagtt cttgagtctc
    15781 aaatgtgata ccgccatgat ttactaattt attcccgcgc atttccggtc catcttctcc
    15841 aaaatttgct gtaaaaatca cgattcctga agcatctgtt tttacttgga tcgatacttt
    15901 ttcatctggg cttgtcaatt ccgcagcatt tagtaaacca gattgttttt tcaacaaaaa
    15961 tggatgatcg atgccgccca ctatcattga ttggcgaaaa tcactggcaa agacctcacc
    16021 taatttttta ggacgttgga agtcaaatgc tgtgccactt actgaaacta cttctcctgt
    16081 aggcgttgta tctttattga gcgtagcaaa taatcggcta ttcaaccaaa gtatatgttc
    16141 gtcgattgac tgtgctggat caccggttaa attgaaatag acatgatttg taggattgaa
    16201 tactgttttg cggtcactga tcccttggac cgtcactcgc catgtatcat cgttcgtcag
    16261 cgtataccgt acttctacat ctaaagttcc aggaaatccg ttttccatat ctgggctagt
    16321 ctgatagaaa atgaccgatg cttcgttttc accattgatg actgtataat gccactgctt
    16381 ggcttcaaag ctaggtgcac caccatgtaa acaatgacca gtgtccgggt ctgtttttac
    16441 ttcgaacgtt tcatcatcta atttgaatgt gccattcgta atccgtccag ccatacgtcc
    16501 gattgaagca ccgatataag ggtctttttc tagatattct tttgcttcat caaaacctaa
    16561 gatcaactct cgtttttcat tatcgattat tgtttgaaaa tgaacaaccc gtgccccaag
    16621 atcactgaca gacaaagatg tcccattttg attcgtgatc gtaatcaagt gatagttttc
    16681 gccaaaattt tgttcattga tttccatgtt ccttgcaccc tcttttcttt catttgcact
    16741 gattccagta tacatggaaa ccgttttctt aacagcttat tccgtgagta acgagaaaaa
    16801 atttactata ttctaataaa agaccgtgaa aaaaaggttg tgacaaaaat attgtcacaa
    16861 cctctttttc cgaacaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa
    16921 acgaaaaata tgaggagcta tttttgcttg gctgttctta ttacttgatg caggacagct
    16981 ttttcacaat ctctttttca atacgattcc agtatataac catgtcgtca gtacatagta
    17041 gatgaaatac aatacgaaga atatcgtaaa cggaacccaa atatctttgt atggattttg
    17101 catgaataga ccaaacattt gtaatccgaa taagacatgg actacaccta agattcctgg
    17161 tgctaagaat aacacgccta cttctctacg gatcgattgt ttaagcaacc cgcgtcgtgt
    17221 tcctatcttt tcaagcattt cataacgagc aatgtcactc ttgcttcctg acaagatctt
    17281 gaacatcaaa cagctagcaa gcatggtcaa gaaagctaaa cctaggaaga atcccataaa
    17341 ttcaaaacca gagaatagac cattatacac ttcatacatt tcatatttct ggttgctgta
    17401 ctctactttt tgcaaagatg gattgttcat tttattttga gcaacaagtg tttcgattgg
    17461 tttcaggttt gcttggaagt cttttacctg aactagctgt aaagtggatt gtggcaagtt
    17521 cagttgatca aattctgatt gactgactac cttgatttct ttttcttgct gttccggcaa
    17581 ttcatagctt cgaagttcct cttgtacagt cagttcattc atttttttag caggaacttt
    17641 ttctttcgtg atcttcggcg gtgttccatc ttcatgtttt atcatgatca atggttgagc
    17701 cgcaaattca cttgcattat agtaaatcgt tcccgcatct tctttttgag tataagaagc
    17761 agaaagtgtt ggtgaaagtt ctttgatttt ttgctgatct tctgcccgag gattattcat
    17821 cactagatca tatccagaat tgttttctgt caagtctgca atttcatttt taaaacctaa
    17881 tcctaccgtc aaagcgccca gtgccaaggc aaacagcata gcgaccattg agagcatttg
    17941 tgtatattca cgaatacgaa agtttaactg tgacaatgtg aaattgttca attttttcaa
    18001 tgaaatctgt tctgatttct ttagtaatga taaaaagaaa atgatcacag aatggaaaat
    18061 gaaataagtt cctaatacga tcgtaactaa ggctacccct ataccaaaga cttgataggt
    18121 ccccacgtgt ttcatcatat agtaaccgca gcctagaaaa gcaattccca gtactacttc
    18181 aaggaaaaac aagaatttat gctgcttgat tcttgttggt gtctgatccg cacgaatcaa
    18241 tgctaaaatc ggttttttga caatcgaaaa agcattgaca acagcagcta ataaaaacaa
    18301 aacagcaaaa aacaaaacag tgatcaacaa cccgtgaata ctaaaaggtg taaaatgcga
    18361 aatattgaga tctaactgat ccactaataa tcggtggacg atacttgtca atcctacacc
    18421 gacagctgaa cccactaaag tagctgcgat ccctactaag aatgtttcag aaaaaatcat
    18481 ctgtgcgatt tttctgcctt ttgctcccag catcataaac attgcatagt ctttttgccg
    18541 catcgtcatc aaaaaggaat ttgcatataa aatataaacg aatgtgatga tccctagtaa
    18601 aacagaaccg aatcggaaaa tgataactgt agccgcaacg atcgtattac ttttcaaaaa
    18661 agcttcgttg cttgccattg attcaaacat gtaaaaaata gcagatgcca taactaatcc
    18721 tgagaataac accaagtagt ctcttaaacg gctcttgatc ccagtaagtg ataatttcca
    18781 aagcatagtc aatctccccc tactgttcca agtttccaag aatagatagt atttctcgat
    18841 agaaggaatc acggctttga tctccacgtt tcacttcttg atggataccg ccatccttga
    18901 tgaataaaat acgttggcaa taacttgcag aaaacggatc atgcgtcaca agaagaatcg
    18961 atacatgatc ttttgtattc aattcgtcca tcgtatctaa aagatcccgg gcacttttgg
    19021 aatccagcgc acctgtaggc tcatccccta atagaatcgt tggttgtgtg atcaatgcac
    19081 gtgcggcggc gacccgttgt ttttgtccac cggaaatctc agaaggatag ctttccaaaa
    19141 tatgagagat ggataaacgt tctgcaattt tttggacacg ttgcttgatt tcttttggtc
    19201 tgacgccttg taaagaaaga ggaacagcga tattttcttg tgctgtcaag ctttctaata
    19261 aattgaaatc ttggaaaata aagccaatct cattcgcacg aaaatctgct agttgatttc
    19321 cttttaatgt ggtcacatct ttttgattga ttcggatatg cccatctgtt ggtttatcta
    19381 atgtggataa aatattcaaa agtgtcgact taccagaacc agaagcgccc atgatcccaa
    19441 taaattcgcc tttttctaca tcgaagctga tgccgcttaa tgcttgcgtc tttttctcat
    19501 tgttttttcc gtatactttt gttacattct gtacttcgac tattttgttc atttctttcc
    19561 ctacccttta attagttttt ccagtgctgt tttcggcacg tctttttttt cgacttcttc
    19621 atacgaagtg acacctttat ttttgttcca ggtgattttt aaatatgctc ctttacgaag
    19681 cggtcgagtc aattgtccct tgaagtccag ttctttttcc ttaccctctt tcgtatagcc
    19741 aggcaggata tatctatagt tgactgtttc ttgtccagag tctgattttg aaactgtttt
    19801 tgtaccatct gtcgtaattt gtacatagta ttcttctcca cccataacta cgtaatctgc
    19861 gattttcacc cctgcaagta ccacaacgat gaaaacaagt agaccgatca gaagtttttt
    19921 cactttttcc ccttctctct tactttatat actgattata gaaaaaagcg aacaattctg
    19981 ccttcgaatc aactatcatt cttctttcaa ttttgtcatt ttctttaaaa caactaaaaa
    20041 aagagttcaa gacaataatc cgtcctaaac tccttcttcc tatcttacaa aaagtatgtc
    20101 acttacggtc tttcatgtcg cctgtattga taacaggttg cgttcctttg tctgtaatga
    20161 ttgagacaag taaattattg atcaattgga ctttccgatc atcggtgaaa ttgatttctt
    20221 gtccatcttc gatttgctct aaggccattt gagtgattgt gacagctcct tcaacaatgg
    20281 tttgtcgagc agacaaaatg gcttttgctt gttgacgttg gagcatggca ctagcgattt
    20341 ctgttgcata ggctaaatgg ttcaagcgtg tttcgattac ttcgacacct gctactgcta
    20401 aacgctcttg cagctctttt tgcaactcgt cagacactgc cgtcgtgttt cctcgaagcg
    20461 tcaaatcatt ctcattgaat gtatcatacg ggtattggct agcgatatgc cgaatggctg
    20521 tctcactttg gatttctaca aaatcttgat aatacgctac atcgaataat gcctttgctg
    20581 tatcaacgac tttaaagact actactgctg agatttcgat ggggtttcca tccaaatcat
    20641 tgacttttaa aacagaacta ttgaaattcc gaactttcaa cgaaacagtc attttttgtg
    20701 ccaaaggtat cgtaaggaaa aagccatttt ctcgaatcgt acctaaatat tgtccaaaaa
    20761 acaaaattac ttttgcttga ttaggactga ctacagttgc cgaacttaac aacaataacg
    20821 tgatcaacca aagaaaaata cttaaaaaaa gtgcccaaac tttcgcttgc cacataccta
    20881 aatagaagaa aaacaatcca actaaagcta atacgaccaa tccgacaatc cctgcataac
    20941 cattgatata aaatgctctt ttttctctca tgctacttcc tgcgctcctt tatccttcaa
    21001 taaatatcta atgttacttt tttaattttt ttttcgaata cgcgccatta caccttctag
    21061 ttctaactct ttgtcttcag tgatgtacca accgcttgcc tgtgtccctc cggctgcctg
    21121 cggtaaataa tccaattttg ttcgaaccca gtgcttttct tctgtaaaat agtcttctac
    21181 caagacctct agatccatcc ctgctgaaag aggcaaatct tcccgaacag atttaaagat
    21241 aaatcgttcc ttcttcccat catacttcaa tattcctgta tcgataatcg gtaaagaata
    21301 ataatccagc tctttcttca ccgtcaataa atgtttgaaa acttcatggt acacttgctc
    21361 taattggcga ccttctgaat tgttcgggta attaaccatc actttttctt tgtctggatc
    21421 atagaaggtt tggcttagtt gagtgatata agtatgtaat ctttccattt ctgtttttaa
    21481 cttttctctt tgaccttctt ctaccttcat atactctttc accctgtttt ctttttagat
    21541 attttctttc ttattttact atagttatgt gcgttaagcg atgaaaaaca gcaaagattg
    21601 gaaggatctt tgctgttttt tcttaaaata tccagttgag tacaggatca atctgtttca
    21661 ttgtcctctt gatccgtcgt aatattgatc gatgtgtctt tagcagtgat ctttagcttt
    21721 ttctgtcctt gttctaacaa agtatttgtt attggctggt agtctttttc aatataagat
    21781 tcaccagacg tttggatagt atagccactg ttttccatct catgcaaaga taaattgcca
    21841 ccgtttagga tgacttttcc ttctttgctg atcaaactgt cttctagatg gaagttgctg
    21901 ttttcacctg tgacgatcaa gttatccaca ttggcctcat ctaatcgaag tgagcctaat
    21961 tcatctttcg cagttattgt tcctcctgta aattcattga acgataccca gccatcatgt
    22021 gtcttagtat tcactttttt gattgatact tcgttgatat caattgcact attattccct
    22081 tcgattgtca attcagataa ttcatgatct gcagggacaa caatagtgat ttgtgcactt
    22141 gtgtcttcta aactaatgat tgcacctgtt gattttttga ctgcattcac agtcaacacg
    22201 ccatttttct cctttatttc tggcttttct gtcttatcat aagtcgtttt tatctcaaaa
    22261 tccaatccgc gtatgaccga aactgtttga ttttctgcat ggatgacgat tttgtttgca
    22321 tccttgattt tttttgtctc agtaaccata tcgatcaacc gaggaccatt atcccaagtc
    22381 agactctttt gagcgcctaa tgtataagtt gcacctgcta ggaggccacc agtaagcatc
    22441 agaccaatac cggtaatcaa aaaatgtttc aatctcaatt tatgtgtcct ccttcaaacg
    22501 cccgctgaat gcagatctct ttttgtaata aaacgtcgtc ccatccattt aacaaagttc
    22561 atcatgacat aaaaaagccc ttttgttcct ttcagcaaca gtggcgaaat aaatactgcg
    22621 cttcctgtgg cgaacagacc gacaccgata aagaataatc cactcagaat cgattgtcca
    22681 aacacactga ttcctgagat gatcatgaat aggccaacac ctaagatact gatacataaa
    22741 acatagatac taaaaatgag cgctagtaaa gcaaccaata gtcccccaat aaccaatata
    22801 aaccccagtg ctagtggaat gaggacagga gaagcaaata aaccgataat gattaaccaa
    22861 atcaggcgaa tttgtctttt tggatttttc actaactcgt tttctgcttg ttcttcttct
    22921 gaaaagtaac tgatttttaa ttttaaggca aactgctttg gtgtaccata ttcatcaatg
    22981 atctgatcta atgtttttcc agaatctaaa aaatattcct cataatactg gatcaaatca
    23041 aaacgatcgt cttcaggaat ttcttgaaga tgatccacaa cttcattcaa atattcattc
    23101 atttgtgctc tcctccaata accggtctaa agaatctcga aaaacaatcc attcatcaat
    23161 aatttcttct aaatgacgac ttcccattgg tgtcaacgag taatatcgac ggtttctgcc
    23221 ttcaaaaggt tcatcatagg tctcaagata tccttctttt ttcaatcttc tcaaaaccgg
    23281 atatagtgta gattcactga cagagagact ttcttgtacg atttttgtta aggcataccc
    23341 atacatatct tccttgctta atgctgctag cacagtacca tcaagaagaa cagttggaat
    23401 ctggatgtgc attacgtcac cttctattct caagtgtaat attttatttc aatctatatt
    23461 atacaacata taatatagtt tcaaaatcag tttgtcaaat acaaaaaaac tgactaaaag
    23521 atttgatcct ttttagtcag caaaaaatgg cttctctttg atttttatta taacagtggc
    23581 ataatccaat ttgtccacat ccagctcagt ggcatgataa cgatcattgc aggtatcatg
    23641 tcagctactg ggaacatttt cacgttgatc attctaaaac cggtagcgac catcaagaat
    23701 ccgccgcaag ctttaaaatc taagatcatg tctggtgtag tcaatggata aataaatttt
    23761 gccaataaga acaaaatata aaaaataatg aattggggaa ttgctatcac agaaacgaca
    23821 taccctaaat tacacgcaaa aatagctgct gtgaaaaaat caaggacaga tttagaaatc
    23881 aaaatcgtac tgtctcctgt catcccagaa tctaaacttc catagatccc cgtaccactt
    23941 gcacaaaata gaacaatgac cgtcactaat gtgctgataa attcatcgtg ggtcatacca
    24001 agcttttcac tagggaagat tttagaaata ggtacttgca tcagcgcagc ccccttattt
    24061 atcccattac ctaaatgaac aatcaaacca atcgctgttc ctatcactaa agcaaaaata
    24121 acagccggca tatttttcat cggcgcaatg gaatagattc ccatccccat cgaacacaca
    24181 ccaaaaacca tcgtcagctg tgctttaaaa tgttcactta atttatttcc tactaatccg
    24241 ccaattagtc cgccaaacaa aacggaacct acattgatca aaactccagt tggcatcaaa
    24301 aaactcctct ctttttctac gaagcgaaaa aaatcagaaa aatttctgta attattgctt
    24361 tcgctgcaag aaagattgta acagacagag aagattacac caattcattt tttgtgttaa
    24421 agtattcttt attggaataa gtaggaggaa tatgatggat atccataaat tcgaagtttt
    24481 tcttgattta gccgaaacaa tgaatttcac caaaactgct gatcgacaat tcaccaccca
    24541 aggaaatatt tctaaacaga ttctttcgtt agaaacagaa ttagacgtca aattattcga
    24601 acgcgcccat agaaaaatcg aattgaccga agctggaagc ttattgctcc catatgtaaa
    24661 aaatgtcgta gaacaatacc atgctatgca agaagtgctt gaaacctata cgaaagacaa
    24721 caatctttca ttaaatatct taacgatacc gacaatgatc aattataaag gtttttccaa
    24781 aatcaccgag tttttgaaac gccatcctga atttacagtc cagttgaaag aagtggaaag
    24841 tgtcgaatta acttacaatg acgccaatga acatagtgac acgatccact ttgctagaag
    24901 tttccaggcc ccaccaagtt cgattgagtg gttgcctact gaaacagacg attttgtagc
    24961 agttctacct aaaaatcatc ctttagctag taaaaagaaa ttggatctaa gcgaactgaa
    25021 aaaggagaac tttttgctcc ttggccccac tacgaacttg tatcaacctg tactagatct
    25081 gtgtcgcgaa gctggatttg aaccaaaaat ctcttataaa ggagcaagaa tcgacttgat
    25141 catcaatatg attgcaaatg acatggggat tgctattgtt atggaaaaaa cagtcaagaa
    25201 tctattaaaa gaaaatactg tgattctccc tatttctcca acaacagaga gttatcttgc
    25261 atttactcgt aaagtcggtg agcattcttt ggcttcagat acattttggg agtatttaaa
    25321 tcaagaagaa aactaagccc tacattttct gtccatctat ccacccaaaa aaagagagcg
    25381 acgcatgact ttcgctctct ttcttgcatc atgtccttgt ttcaatgaca cctctaacat
    25441 ttctcgtagt tcaataagaa agcagcgatt tttatgccaa aagaaccgta agaacatttc
    25501 cctaatcaca aaaaaacgac taaaaacccc taaaaacctt caatagaatt tttaggggtt
    25561 ttattctttt tcctattgtt tacttaaccg tatcattgct gtcgttccta ctccttcgat
    25621 actgctataa tcaatacgtc catcatgcag ttctagaatt tttttaacca gtgaaagtcc
    25681 tagcccattc ccagaaattt gacgacttgt atctccttga taaaattttt caaacattcg
    25741 atctctggtc tcttcattca ttcctacacc tgaatcggtc acttccagta caatctctgt
    25801 ggctgtctca aatagtttga tatgaatctg tccattgatt tgattgtact ttatggcgtt
    25861 atccatgata ttcagccaca cttggtacaa aaactcttca ttgcctgtgt aatttactgc
    25921 agcaagttcg atatccaatt ctagctgttc tttctcccat ttaggctgaa aaaaaacgat
    25981 tacttctctg atttgttcat ctaatcgata ctctttcttt tccagttgga tacgctggtt
    26041 ttccagtttg ttcaatttta agatgttctc tgttaattgt gaaagctgcg tgatactttc
    26101 gataatccga tataaaaata tttggcgttc ttcgtcagag agatttgggg cttgtaacaa
    26161 ttgaacatat ccttggattg ttgctagtgg tgttttgaat tcatgggata cactggacac
    26221 aaagtcattc ctcagtgtct cgatactatt gagttcttgg accataacgt tgaaatcttt
    26281 atacagttgc tgtacttctg ctactttctg ctgttcatcc attcgaatcg aaaaatctcc
    26341 cgttgctacc agactcatat ttgtccctag cgcactgatt ggatgcagga tacgccgccc
    26401 aacaaaaatc gatattcctg tacccacgac catactgaac cccgcaaaga cgaataacgg
    26461 gtataacgtt ggttttccag ccgattcagc aggcgagata gaatgtcgag acaataagaa
    26521 aataaaaccg agaaaacaca gcagtgtcac taagatcgaa atgaagacaa tactagcaaa
    26581 atagatccat aattgtgaaa atagcttttt tttcatcttt aaataaccgc cttatagcct
    26641 agtccccgta ctgtgatgat ttgaaaatct tccgtctttt caaaacgggt ccttaaacgt
    26701 ttgatatgta catcgatcgt tcgttcttct gtattcgtat ctaatcccca aatatcatcc
    26761 atcaactgtt ggcgagtgaa gatcttgttg ggataagaca gtaatttata cagaagcaga
    26821 aattcttttt gaggcagaat caacgaatgc tgatcttgta acactgtata agcatctagc
    26881 tctaattttg tttgtccgat tatcaagcta ctgctgtaat tgatctttga acgtcgaagc
    26941 aatgcttcca cacgtaggat catctcattg acatcgatgg gttttgtcat ataatcatct
    27001 gctcctaatt tgaacccgcg tttcttatcc tcaaaatcgg cctttgccgt aatcattaga
    27061 acaggtgtgt caaatctggt gctacgtaat gagtctagca agtcatagcc atccattttc
    27121 ggcatcatga tatctgtaat gattaattct atacgtgtcg cttctagttt tttcagcgca
    27181 tcctctccat tcaatgcggt gatgactgaa aagcccgctc gttccaacac agaacggtaa
    27241 agcaactgta attgcggatc atcttctact actaaaatac gattcattga tctccctctg
    27301 ttttttgaaa aatttctaga ttttttcttg tagttcatct tcagttaaca tttatttcgt
    27361 atactacgat cattgttctg atatacttat tagtataccg aatatttcaa tacgggagaa
    27421 gggtgattat gcttcaatta aaagatataa aaaaatatta taaagtcggc gaaaccacca
    27481 ccaaagcatt ggatggtgtg tctgtcgctt tcagacaaaa agaattcgta gcgattttag
    27541 gtcctagtgg ttctggtaaa acgactatgc tgaatgtgat tggtggacta gataattatg
    27601 attccggtga tatggtaatc aacggaaagt ctactaaaga ctttaaggac agtgactggg
    27661 atgcctaccg aaacaactct atcggtttca tttttcaaag ttacaacttg attggtcatc
    27721 taggcattat tgaaaacgtt gaacttggga tgacattaag tggtgtttct aaagacgaaa
    27781 aacgaaaacg ggcagaagat gcattgcacc gagtcggctt gacaaatcat atgcataaaa
    27841 agccaaatca gttatctggt ggacaaatgc agcgagtggc catcgctcga gcactagcca
    27901 atgacccaga tatccttttg tgcgatgaac caaccggagc gttagataca gaaacaagta
    27961 tccagatcat ggaattgatc caagagttat cgaaagaaaa attagtgatc atggtcacac
    28021 ataatcctga actggcccat caatacgcag atcgaatcat tgaattttct gatggtaaga
    28081 tcttaacaga ttcccatcct cacatcgaac gaccaaaaga tgatcaattt aacttacgca
    28141 gaacaaagat gagtttttgg acagcgttaa agctttcctt caacaatatc cgaacaaaaa
    28201 aaggacgtac tttcttgacc tcctttgctt ccagtattgg gatcatcgga atcgcgatcg
    28261 ttctgtccct ttcttctgga ttccaaaaac aaatcgataa cacgcaagct gaaacgatgg
    28321 cgaaatttcc gattactatt tctaaggtaa cgactaacca gactcgtgac gatgccggat
    28381 tgggtgcaag caaagcggat tatccagaca gcaaaacgat tactgcaaaa gtcagcgaag
    28441 aagataaagc acagcacacg aataagattg atcaaacata cgtcgattac gtaacagaca
    28501 tcgatcctaa cttaagtaat aatatcggat ttacccgtac tacaggaatc aatcttttac
    28561 gtgatgtaaa tggcaaagta cagcctgtca gcttctcgaa tcaaaatcct gatacggaat
    28621 ctctttcttt atctagtacg atgtcagcaa tgacaggtgt gggagtgtca agtttcccta
    28681 cacagcttga cactagcaaa gaaaactttt taaaagacaa ttattcttta cttgccggaa
    28741 gttatccagc ctcagcaaca gatgtcgtgc tgatcgtaga cggcaataat aatactaata
    28801 tcaacgcatt gaagaatctt ggatttgatg tgaaagaaga cgaaaaactt gattttgatg
    28861 atatcgttgg tacaacattc aaattagtaa acaacaatac ttactataca aaacttccaa
    28921 ctgggaattt tatccctaat acagattatg atgcgatgta tcagaatgct tctgatgaat
    28981 tgaagatctc ggggatccta cgcgtgaaat cttcttctac aatgaatctc ttatctccag
    29041 gaatcgctta tagcgatcaa ttaacgactc aaatcgtcaa cgaaaacaaa gaatcagaaa
    29101 tcgtcaaagc tcaaagagac agtggtgtaa atgtcttaac tactgaaaaa gttgacgaaa
    29161 atgccaaaca aacattgctt agttatttag gtggagacag cttgccttca agtatcatga
    29221 tttatccgaa caattttgaa gacaaagaaa agatcttgga ttatctagat gattacaata
    29281 aaggcaaatc agatgaagat aaaatcattt atactgattt agctggaacg atgactgaac
    29341 tgactggcgg attgatggat gctatcactt atgtccttat tgcttttgca gggatctctt
    29401 tagtaacaag tatgatcatg atcagtatca ttacttatac atctgtgatt gaacggacaa
    29461 aagaaatcgg tgtactaaaa gctttaggtg cacgtaaaaa agacatcact cgcgtatttg
    29521 acgcagaaac gtgtatttta ggtatttctt ctgggatatt aggtgtgttt attgcatggc
    29581 tagctacgtt ccctatcaat agcatcttat acaacatgac ggatctaaaa aatgttgctc
    29641 aactaaatcc tgtccatgcg attattctag tgatcgtctc tactatattg acgatgcttg
    29701 gcggtcatct tcctgcacga atggcagcga aaaaagacgc cgctatcgct ttgcgtgcag
    29761 aataaggttg tgacaaccac atttagattt gagtcataag agcgctgaaa tagtagaaaa
    29821 cagcaagaaa cgaggaagta atatgttcct tgtttcgcgc tgtttttttt aattattttt
    29881 tataattctg gtatactttt ctttcctttg taccacaact cttctggcgt atacctgtct
    29941 tttccattta tgaatactgt tccatctgct tcaatcgtta cttcagtccc aatccacata
    30001 ttacgagaaa gtgcgagaag attttttctt tttcctcttc ctttttttcc aaattgcaag
    30061 gcatcggtta tctcttctgt ccaatgagat ttcacgtatt ttacttctcc gttttcaaat
    30121 gtaactttca aaatattcgc tatattttcc acttttactg ctttaggaaa tgactcctcc
    30181 atttttttca ctttccttcc tccaacacta agtatgcgct ttcttttagt gataagtata
    30241 tcatagttta ttctattatc aaaaaaacgc atccattcca ttgtagaata ctttaccgaa
    30301 caagttgaat tgttttcctc tttttcacct tttactatag ataggtaaag acaactaagg
    30361 aggaatctct catgacagat caaccgtatg atttaagaaa agtcatcgaa gaactaaaaa
    30421 cacttccagg tcaatatcac gaaacagata ttgaaatcga tcctgaagca gaattatctg
    30481 gtgtttaccg ttatatcggt gctggcggta cagtaaaacg tccgactcaa gaaggaccag
    30541 ctatgacttt caacaatatc aaaggtttcc ccggcacacg tgtgaacatc ggaacaatgg
    30601 ctagtcgtaa acgtgtaggt gaaattttgc accatgatta tcgaacactt ggtcgtttct
    30661 tgaaagacgc tgtagaaaat ccaatcaaac ctgtgaaagt agacaaagca gacgctccag
    30721 cacaagaagt cgttcatcta gctaccgatg cagacttcga tattcgcaac attttgcctg
    30781 cacctacaaa tactcctgaa gatgctggtc catacatcac aatgggtgta gtcttaggat
    30841 cagatccaga aaaaacaatg agcgatgtaa cgatccatcg tatggttcta gaagataaag
    30901 atacgatcgg tatgtacatc atgcctggcg gacgccacat tggtcacttc caaaaacaat
    30961 tcgaagcctt gaataaacca atgcctatca ctatcaatat tggtttagat ccagcaattg
    31021 ccattggcac gactttcgaa ccacctacca ctccacttgg ctacaatgaa ctatggtgtg
    31081 caggagcttt gcgtaacgaa cctattcaaa tcgttgatgg tatagcagtc gatgaagtgg
    31141 gtattgctcg tgctgaattc atcattgaag cagaaatcat gccaaatgaa acaatgcaag
    31201 aagatatcaa cacgaactca ggaaaagcaa tgccagaatt tcctggctat actggggatg
    31261 ctaatccagc tgtacaagta gtgaaagtca aagcagttac tcaccgaaaa gacaatccaa
    31321 tcatgcaaac aacgattggt cccagtgaag aacacgtatc tatggccggt attcctacag
    31381 aagcaagtat tcttgccttg gtcgataaag ctattccagg aaaagtagta aatgtctaca
    31441 atcctcctgc aggtggtggt aaattgatga ccatcatgca aatccgtaaa gaaaacgaag
    31501 cggatgaagg tattcagcgt caagcagcta ttcttgcttt atcagccttc aaagaattga
    31561 agacagtcat tttagtcgat gaagatgttg atattttcga catgaacgat gtagtttgga
    31621 ctttcaacac tcgtttccaa ggagataaag atatcatcgt gatcccagga atgaggaacc
    31681 atccattgga cccatcagaa ttaccagaat ataatcctgg ctctattcgt ttccgtggga
    31741 taagtgcaaa aactatcttt gacggtacag ttcctttcga tatgaaagaa cattttgtac
    31801 gtgcaaaatt ccaagaagta gaagattggg aaaaatattt gaaataatga atgatctgca
    31861 actgttttga catcataaaa aggagtgcgg aaaatggaac aattggcaca acggaagaaa
    31921 aaaatcgtga ttggtgtaag tggcgcttca ggcaccattt atgccatcaa cctagtgaag
    31981 aaactaaaag aatatccgat gatagaaaca cacggaatca tcagtccatg ggcaaaacag
    32041 aacttaaagc tggaatccga cttatcacta actgaattcg aaagcctgtt tgattaccat
    32101 tattcaaaca aagatttagg tgctgctgtc gccagcggat catttttgac cgatggaatg
    32161 atcatcgtac cggcaagtat gaaaacagtc gcaggtatct ctgttggttt aggcgacaac
    32221 ctgattgcac gtgctgctga tgtaacaatg aaggagcaac gaaagttagt cattgttcct
    32281 cgtgaaacgc cattaaatgc cattcacttg gaaaacttga ctaaattagc acgactaggt
    32341 gtgcaaatca taccaccaat tcctgctttt tataatcagc ctcaaacgat ccaagatctt
    32401 gttaatcacc atacaatgaa acttttggat caatttgaaa ttgtaaatga gcattcaaaa
    32461 cgttggcagg gtgattaata tggaaaaaga aacgatagtt gaagtaacca aactaggttt
    32521 cacgatccaa gctgctgtta aagtaatcgg taaagactta ttgatcactt taacaggcgg
    32581 agatacacca catatcggaa cagtcactac attttctcgt gatacagaga tgcaaactgt
    32641 acgtttccct agccacgatg gtcggttcca taaagacgat gtcttagccg aaaaaatagc
    32701 tgtgatcatc aaaactgccg ttccgggaag ttgtacgatc acttccggta tccatgttga
    32761 ccatatctcc aatgcacaaa tcaacgcctc ttttccgatg tcagaagagt taggttacaa
    32821 gattttagat tggttggaaa aaatagattt ccatatcaaa taaccagttt attataaaga
    32881 tggtgaaaaa ccattatgaa agaagaggtt gtgaaatcag cgttatgacc tgagtatgag
    32941 agaaaaaaat ggaaaaatag cttctcatat tttgccgttt ttgagctaat accgagggac
    33001 agctgattga acgccgttta tcaagaggtt gtgataaagc cgcttcgttt cgagtagtaa
    33061 gaaaaatttt gtaaacatgg gtttccacat ttttgcataa atttgactta ctaccgagaa
    33121 actggctttt gaacaccgtt tatcaagagg ttgtgacacg tcttttgtca caacctcttt
    33181 tatttttgct tcactgtaac tgctacaata tcaccgattt cttttccgat gtttttacga
    33241 atatcttttc gtagtccaag gatgtagcag actgaaccat ctggattttt cacgcccata
    33301 ttcacgatac tgccttcata cggcacattg tcaaaagttg cttggacttt aactcttcca
    33361 gcaccgaatt cttttcttat atcatacgga aaaataatat atgccccgcc cttgccgact
    33421 tcggaagcat agatttttga ttcaaaagaa taaatttccc tcattttatt tctcctattt
    33481 tttacatcta gtatagcata gcaaaaaaaa gaaggaactg tgacaaaagt cttgtcgcag
    33541 ttcctttttt cgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatagt
    33601 caacaaacat gagaagctgt tttttgaaat tgctccttgt gactcagagt taaacggcag
    33661 gctcacaacc tcttccttaa acggtgttca aaagcttgca tctacggcac taagcccaat
    33721 cagatgaaaa atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca
    33781 gctttttcac aacctcctac atggtgttca aaatattatt cgccttttgc ttctttcact
    33841 aattttgcga atgcttgttg ttggaattca gcagctaagg ctttcgtacg ttgttcttgc
    33901 tctgctttgc tcatttttgg attttcagtc attgctttta ccataccgtc ttgaacataa
    33961 gcttttgctt cactttccat cgtactttgc tgtttcttca ctaattcagc taacttggct
    34021 gcttggtccg tacttaattc tacccatgtc tctgggattt tgaatgtatt cactcggctg
    34081 tcatattcgt gattgttatc agcaatattg aaccagaatt tatacatgtc gtttttgtat
    34141 tcccaataag tagttttcgt cactttttca gcatcgccgt ctgtcttttc tactttattt
    34201 gtttcgttat ccgtaccagt tgcttttggt ttttcttgtt tttcatttgt tcggtaaaga
    34261 tacacttttt cttttccatt ccctaaagct ttatacaaaa gcatatctgc tccttgggaa
    34321 tcagcactgg aaacaatttt ttctgttttt gtttccgtta ctttttccat tccaaagtga
    34381 ttggacaaat tagcgacgat caaacttagt gaagcgacga agattagtcc gaaaatcaaa
    34441 gataaaaagg tttgccatgt ttttttagcg aacacgttcg ttaaagcaaa agcaagcaag
    34501 ctgacaatca aaactccaat aatcatgcat tatcccccgc tttcattaga acaggttctt
    34561 ttttcttcaa taaaaaggca ataataaagc caagaatccc aaagatgatc gctacgataa
    34621 acgcggcatg gtaacctgac agtgtggcat tgattgcctg atctttataa gctaatggcg
    34681 tattatccaa tacagatttg cttgggatat ttgcttttgt cacattcgtc aacacactga
    34741 tcaaaatagc tgtaccaatc gagcttgcga tttgacggaa tgtattattt accgctgtcc
    34801 catgactgat caagttattt ggcaatgcat tcataccaga agtcgttacc ggcatcatga
    34861 ccatggagat cccaaacata cggatcgcat aaaggatcac gatatataaa actggagtcg
    34921 tttttgtcaa gaaagcaaat ggtgcagttg ccgctgtcaa aatgaacatc cctgtgatgg
    34981 ctaaacgttt cgcgccgtat ttatcgaaaa tcgcacccgt cacaggcatc atagccccca
    35041 tgatcaatgc acccggcaac aacatcaagc cagaatggaa tgctgattct ccacgaatat
    35101 tttgaatata caatggtacg accatttctg cccctaccat cgccatattt gttacaccag
    35161 ctaaaacagc tgcaatcgtg aatgtagatg atttgaatac acgaagttcc aagaatggat
    35221 gttccaaatg taattgacgc catgagaaca aggcgatgaa aatcacacca acaactaaga
    35281 aaccaattac tttcaagctt ccccagccgt catctcctac actagaaaat ccgtaaagta
    35341 aactaccgaa tccaatcgtt gataaaatag cggataaaat atcaatgcta ggatttgaca
    35401 atggaataac acttttcatt aggaagaatg ctaaaaccaa gacaagaaca acgattggca
    35461 gtaccatacc aaacaagtca cgccaatggt agttatcaat gatataacca gataatgtag
    35521 ggcctaaagc aggagcaagt ccaataacga tccctgacat ccccattgct gatcctcttt
    35581 tttctggcgg gaaaatagat agcatgatat tttgcaataa tggcatcgat actcccacac
    35641 cgcaagcttg gatcaaacga ccgattagta atgtactaaa attaggtgct gtaaagcaag
    35701 taatcgttcc gatcaaaaag atcgtcatgg cagaaagata taaatttctt gaactgaatt
    35761 tattgatcag ccatgctgtt attgggatca tgatcccgtt gactagcaag aaaccagtcg
    35821 ttaaccattg cacatcagac gctgaaatat cgaaagcttt catcaatgta ggaaaagctg
    35881 tcgtcaataa ggtctgattc aaaacggtac aaaatgtacc aattaataag acaacaacta
    35941 aaagtgtccg attatatggt tttccgtaaa tatctacggg ttggttgtta ctcatatttc
    36001 tccttctttc tgaatttttt ctgaaactac tagaatactt tagtcctaaa ttcgctattt
    36061 gtcaacctac ttgacacata agttaatacg gatataatta agggaagcaa gaggacaaaa
    36121 ggagtgacaa aaatggttgg ggcttccctt aaacgtttgt tggaaaatga tcaattggtt
    36181 gttggcatca gtgaattaag tgatatcgta ggtgtgtctc cacgtcaatt aaggtattgg
    36241 gaacaaaagg gattcattcg ttcgatcgaa gctgatgcga attgtcctag aaaatatcgt
    36301 ttacctacag tcataaaagt agaactgatc aaaaaatatt tagatgacgg atttactttg
    36361 tcaaaagctg cagaaaaggc agaaatccgc caaaagaaaa tgcaccatgt ccgtaaagtt
    36421 ttttcaaaag caatcaaaga tatcgaattg atcgacgaac gctatacgat tttacaaatc
    36481 ggtaacttca aagaagagaa tgctaagatg tacatcattc atgacaacga gacagacgaa
    36541 ttaacttaca agctccttcc tgtcgatgaa aaagctgact acgaacagtt gttaaaagaa
    36601 ctctaaacgc cactaatctc ctaagtacca agctttttaa taagtagatg ctacataaat
    36661 acttgaaaaa aggcctgttt gaacataaga atatccgaac ggtgatctgc gtttctttca
    36721 tatagaaagg aattctccat cactgttcgg atattttttt atttttttcg gttactttct
    36781 tctaatacat ctgttagcca atttgcatat tctgtttccc gattgatcgc atgcgctaaa
    36841 atcaggtagt gtccgtaatt ttcatgtttt tctttttcag taggaaagat cgtttttttt
    36901 cgctctaata gatgaagtcg tttttcttca tgaaggtcac gctgctgctg aataatttct
    36961 actaatgccg gatcattcac gtctttgacg aaatacaatt tcagaacaaa ttcgtctcga
    37021 ttaaccggta gttcattggt gggtgtatga atccactctg ccaattgttc cttcccttct
    37081 tctgttaatt cataaacttt cttttccaat ttttcacctg tgatctctac ttgatgctga
    37141 atgattcctt gctcttccat ttttgcaagt tcaggataaa tctgactatg ttttgcttgc
    37201 caaaattctc ctatttcatt tttgaacgat tgattcaatt catatcctgt catcttcttc
    37261 ttacttaata accctaacaa aatatatcga agtgtatttt ttcttgccat cagttttccc
    37321 tccttgacaa atctttaaat ccattctatc ataaatgagt aatcgaaaac atgtagttta
    37381 ttacatgttt taatttataa ggagatgctt aaacatgaaa gaatttaaag aattggaaga
    37441 ttttattgga actcacttta tctatacgta tgacaatggt tgggaatatg aatggtatgc
    37501 caaaaatgac catactgttg attaccgtat ccatggcgga atggtcaaag gccgttgggt
    37561 aaaagaccaa gaagctgata tcgttaaatt gacggacggc gtattcaaaa tcacttggac
    37621 agagccaaca gggacagacg tggcattgga ctttatgcca aatgaaaaga aacttcacgg
    37681 aatgatcttt ttccctaaat gggttgaaga acatccagaa atcactgtta ctttccaaaa
    37741 cgaacatatc gcagaaatgg aagcagctcg tgaaaaatat gaaacttatc caaaattact
    37801 tgttcctgaa tttgctacga tcacttatat gggtgatgca ggtatagaca atgaagatgt
    37861 tattagcgaa gaaccatacg atggaatgcc agatgatatc cgtagcggaa aatacttcga
    37921 tgaaaattat aaacgagtaa aataaggttg tgaaagagag gttgtgaaat cagcgttctg
    37981 acctgagtat tagagaaaga aacggaaaaa tagttcctca tgttttgccg ttttttgagc
    38041 taataccgag ggtcagctga ttgaacaccg tttatcaaga ggttgtgaaa tcagcgttat
    38101 gctttgagta ataagaacgc tagttagaaa atagcttttc atattttcta ggctagtggg
    38161 cttattaccg agaagcagcc gtttgaacac cgtttatcaa gaggttgtga aatcagcgtt
    38221 ttgacctgag tattagagaa acaaatggaa aaatagttcc tcatattttg ccgttttttg
    38281 agctaatacc gagggtcagc tgattgaaca ccgtttatca aagattgtaa caactgcata
    38341 ttcacacagt taaattagtg acttcaaaat gaaataatgc tcccagcaaa aaattaggct
    38401 gggagcatta tttcgttatt ctgttcatca aaaatcagcg ttttgattcc atttcatcac
    38461 aagttcctcc tcatttactg cttcatcttt ttgctgtgtt tgaattgtaa aaccttgtga
    38521 aagatagaaa tgaatagctg attgattttt ttgatagact gtcaaagtca gtgttttatt
    38581 ggtttctttt atttttttca ttagttgcgt accgattctt tgttgccggt attccctttt
    38641 cacaaagatt cctgcgataa actgatcaat caccccagca aaaccaataa tttcttgatc
    38701 tatttctgct aagtaaatca ctgcatctgg taaagctttc ctaacagatt ctacttgatt
    38761 ctcccaataa gttgatggaa tgaattcatg agaatccaag ttagcatgca gccaaatcga
    38821 tagaacagat tccagttctt tggcagacaa ttttgttgtt gtgcggatca ttttttctct
    38881 ccttacttat tcattgattt taaaataaaa accatttttt tgaagctctt ttacaagttt
    38941 tcgcccctca aaaaagtata tcttctcttg ttttactttt ctaataccaa aagaaacagc
    39001 aactttagga tcatcagctg aaacgattcg ataagttcca ccaggcaatt gatccagctt
    39061 gactttccca tgatggtcgc tttgtactga aaacggcaca ccatttctag taagtgtttt
    39121 tttcttatgt ttcaaaatga atgaactacc atttaccggt ttccctgacg aatcactaat
    39181 aataaatgaa aaatcaagca cttttttact taatctatac tgatagatta gtcgtccgat
    39241 aaacactaac agtatgacta cagctattat cgttcctgca agaataaacc attgccgcat
    39301 ggttctttcc tgatttcctt ttccttcttc tttttttacc gattcgttat aaggaatccg
    39361 atgtcctgtc actagcaaac gatgcgtgtt gatcatatac ggcgtacatg taagcaaggt
    39421 aactaagtct tctccttctg aaatcgttag aacagacgtg tcatctggca gtaccacttg
    39481 tatattttta acttgataag ccaatttctc ccccaaaaca gtcaaaataa acgtgtctcc
    39541 gttttctaaa cgatctaatt cggtaaataa ccgtcgatta ggtaaaccgc tgtgagcaga
    39601 gatcactgaa tgcgtcgaat ttccaccaag cgggaaagag gttccttgca agacgcctgc
    39661 tccattttca aggatcctac cattgagccg atcataaagt gaaatattta attggatctt
    39721 aggtatattg atacttccga tcagccattc ctctaattgg ctggatgttg tactttcatt
    39781 tctgttcttt tcattgaaag gatcagtacc aggattgaat ccttggtcag ttaatcgttg
    39841 gtttttctcc tccattttct ttcgctgcac ttcaatttca gctgcggtcc gtttttgtac
    39901 ttgttcgata cgtttttgat caataaaact atttaaagaa tccacataaa atggatataa
    39961 agcgatcagt aaccctacga cgatacatat taataaaaac aaacgaaaca aaagtcgacg
    40021 agactgtttt tgcttactct gcttcacatg tgtcctccct tgcaagtttt tttgttcttt
    40081 cttttattat atgggttcag gaaaaaaata gaaaatgaaa gccgatgagg ttgtgaaaaa
    40141 gctgtcctgc atcaagtaat aagtacagcc caaaaaaata gctactcata ttttttgttg
    40201 ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgaa
    40261 aactgcgtta tgctttgagt aataagagcg ctagtcagaa aatagcttct catattttct
    40321 aggctagtga gcttattacc gagaagcagc tgattgaaca ccgtttaccg agaggtcatg
    40381 aaaaagctac tttgtttcga gtattaagaa aaattctgtt tcaaaacaag gagatgcaac
    40441 aaaacttatg tcgcatcctc tctccttaga actttcactt atgtttttct tgtaaaattc
    40501 ataaatattt tcatgaattt tctaatttct tgcctacctc tcgcatagga tatatgatga
    40561 atttatctaa agtttgcaaa ggagttcgac aattgaaaaa atatggccca tttttagcaa
    40621 tttttttcat tgctttggca tttctcatgc ctcatttatt cacacataaa ctaattttgg
    40681 gtgctgatgc cccattccat tacaatcggt tctatgatgc cgcgcaacaa attaaatatg
    40741 gggatttcca ttattttcct tccctttatg gattccagca aagtggcagg atcgtgaatg
    40801 ccgtttacgg cccatttttc gcttatttac aaggattgat cgtgttgctt gcaggtagct
    40861 ggtttcatta tcagattctt tcaaatttca ttctttatct tatttcagga ttttctatgc
    40921 tgattttact gagatatgtc aatgttcgaa attgggtaag tgtaccagta gccgttttat
    40981 tcatgagtac gtattctatt caatactggt ctatcaacca aggattcact agctggggga
    41041 cttgttttta tcctttatgt atgatcccta ttgctgattt cgtccttcat aaaaagttcc
    41101 ctgttatcaa agtcgctgtc tcagtgggac ttatgacaca gatccattta ctgtcttcga
    41161 tcatgttagc tttgatgtat atcccttttt atctttatta cttttttaac cagactgaaa
    41221 aaggaaaagc actgcttcaa ctgattaagt cggtcttgct ttattttgtt ctgacagcaa
    41281 atatttgggc aggattagct attgtttaca gtgggaataa gattcttcct ccctttgtta
    41341 acagagaaat gagtcaaaag gcgatagatc tggatggcag ttattggctc cattacccta
    41401 aggcctttcc tatattgata ttatcaggtt ttttgctttt tattttcttt caacaaaaga
    41461 acaccttatt ccaaaaaatc gtgttgtaca caagtcttgt tttctttttt ctttctacta
    41521 gcttgattcc atggacgaca ttgatcgaaa aaaatgtgcc ttttattagt ttgatccagt
    41581 ttccatttcg atttttcgtg ccatttacgc tattgcttct actttacctt gccctttcac
    41641 tgaaccagtg gtctgaacaa aagtggttcc gtcttttaag tatatttggc attcttattt
    41701 tttcagcaca gacgatccag aacttatacc agcatctgga aaagtgggaa aatgaaacat
    41761 ttgtcagtcg acatacttat ctattcgata cgccggaaga agcaaggaaa acattcttca
    41821 gcaaagatat gtctaccagc ttgttcgttt tccaaaaaac cacacctgac tatctgccaa
    41881 tctataagga gacaaaagac aataaatacg accggtataa cgaagaaata ctagaaaacg
    41941 aaacaacttt tataaaaaca catccaggcg gtcttttgac aatcaagtgg aaaaacactg
    42001 gggacaaaac tgttcatatc cctgttatcg tctacgatcg gactgtgcta cagcaaaatg
    42061 gaaaaacatt gactgattat gaagtaacag atatcgggac cccaatcgtg aagcagcaaa
    42121 aaggaatcaa cgagctcacg cttcattatc aaacgccaat ctatttctat ttcattcttt
    42181 ctcttacttt gattggctgg tttaccttgc tatgtttatt tatttatcat agatacaagc
    42241 ttttacgtgc ttaggcaaaa gggataaata catccgatca aaaaactctc caaacggtat
    42301 aatcgtttgg agagttttat tttaatcagt ttttttatgt tatatgttat attttttatt
    42361 cgttcacatc taattcgatt tccaccccgt agtgatcact gatgattgga ctatcgatcc
    42421 catcaaaaat ccgttgatat tttttaacct gcattccttc agggacgaaa ataaaatcta
    42481 tacgcaattt ttctgtattt tgttcccaac catctatttt cttttccaca gtagctgctt
    42541 ttcctttttc attcgcgaca acatacgaat cttgaagaag aaggcaactt tctcttacag
    42601 tataataacc ttgagagtct actggattat tgaaatcacc taggaaaaaa agtggtacgc
    42661 gagtttccaa aaagtagttt tccaagtttt tccactcaaa ataaaagcca ctttttttat
    42721 ctgtccacca agaaaagtgg cagctcgaga caaaaatgtc ctgatcatct atctttgttt
    42781 tcccaatcaa gatcttgcgt gtctgataat cttctttctt ttgaaattgg gagacggtaa
    42841 ggacctgact ttccaatgtt tttttcgtaa gcagtgcatt tccttcttca tatttatcat
    42901 aaccgatgtg gctcatttcc caactccaaa aatactcttt tccgtgttcc tttaaaagct
    42961 gaactaaacg gtaggcaaaa ttatctttac ggataggtac ttgattcttt accggacaga
    43021 acttcattag cttcgcaggt tctacttctt cagattccag taattggttg atttcttgta
    43081 aagcaatcac ttcataatct tctaacagga tcttatctgc taattcttgc aattttttct
    43141 ctggttctgg ctcaagccag ctatgcgtgt tgagtgtcat gaatttcatt ggttttctcc
    43201 ttgtcttcat ttcgaaacaa aagggttgtg acaaaatttt tgtcacaacc tctccagcaa
    43261 atagtgttct cctgctaact cctcagtaat aagctcaatg gaccaggagc tattttttgt
    43321 ttggctgttt ttatcacttg gtgcagggca gctttttcac gacctctcca ctaaacagta
    43381 ttcaaactgc tgcttctcgg taataagccc aaccaaacga aaaataggag gagctatttt
    43441 tgtttggctg ttcttatgac ttgatgcagg acagcttttt cacaacctct ccttacattt
    43501 taatggagcc gatcacttta ccagctgtca ctgtacctaa ttgcttgatc actacttctt
    43561 ctactttatc gtttgtaaat acgatcatga tcgttggatc tttttcttcg ttttggatca
    43621 catcaagatc catctcagct aatttcgttc ctgttcctac ttcttggcct tctttgacag
    43681 caatctcaaa agctggctga ttcatttgga ctgtatcgat tcccatatgg atcaaaactt
    43741 cgataccatc tttcgtttcc agcccaattg catgtttgct agggaaaata cttgtcactt
    43801 ttccagcgat cggcgcaaca acttctcttg atgttggaat aacagcaaag ccgtcaccca
    43861 tcattttttg tgagaatacc ggatctttta cttcagataa aggaatcact tctccagaag
    43921 ctgcggaaac tagttcttgt tctataccta agtattgctt actacctgct tgtccatttc
    43981 ctgtagaaac catttctggc tctggaatct ctgctcctga ttgcagcaga tcttcgatat
    44041 ctgatttcaa gacatctgct tttggtccat aaactgcttg gactccattg tctttgacga
    44101 tcaatcccat cgcccctgct cgtttccagg cttcttcagt ccctactttt tctcgatcat
    44161 ttacacttac gcgtaaccga gtcatacaag catcgacatc tttgatattt tcttttcctc
    44221 ccagcaaatg aatgatctgg accacttgct gatctgctgt tcctgttccg ctgttagata
    44281 caacggtttc ttcactgtca ttgtcgtaat ttccgttacg tcccggtgta gcaaagttga
    44341 attttttgat caagaaattt gctaagaaat acgtaacaac accaaaagcg atcacacaca
    44401 acacgaagtt gataagatct ccacctagac ccgctttgat agctaacggt gtccgagtca
    44461 gcaattcgat attcccaaat gaatggaccc gcaatggcaa gatatctgcc atcgcaaatg
    44521 cagccccttg gatcactgaa taaatgacat ataatggcac agcagcaaac ataaacatga
    44581 actccaatgg ttctgttaca cctgttagaa agacagccaa cgctgctgaa aaatacattg
    44641 atttatatct tgctttctta tcaggatcga cattacgata catcgcaaaa gccattccca
    44701 tcaagatacc tgaagaacca atcatttgtc ctactttgaa acgagccggc gtccagttat
    44761 gcaacacaaa ctcatattgc gacatatccc ctgcaccttt aagattcact aaatcagtgg
    44821 cccaagccaa ccataacgga tcttgcccaa atacttgtgt ccccgcctgt gcgcctgata
    44881 aaatctcata cgatccgcca agctgtgtat agttgatagg aatcgtcagc atatgatgca
    44941 atccaaatgg caatagtaaa cgttctaatg ttccaaataa aaacggtgct agaatcggtg
    45001 cgctttcttg tgattctgca atccataaac caaaattatt gattccagcc tgtacgtttg
    45061 gccacaccac agcaagaatc aatgccacga ttgttgacca taagataaca acaaacggaa
    45121 caaagcgctt tccattgaaa aatgacaaag catccggcaa ttttctataa ttatagtact
    45181 tattataagc cattgccccg acaaatccag cgatgatccc tacgaatact cccatattca
    45241 aagctggtgc ttccaataca cttgtaaaaa atcctttaac catgatcttc gtaccgaaca
    45301 gagtgtgggt aaatgcatct tcattcgcaa gcatgtcact tgtgacacca aagatagccc
    45361 cagtgatccg attgattaaa ataaatgaga tcccagctgc aaatgctccg cctgctcttt
    45421 cttttgccca acttcctcct attgctaaag caaataaaat atgaagatta ccaataattg
    45481 cccaaccaat attttcaatt actccgcccg ttgtgacaag cggcgtccaa tcaggattga
    45541 tcaagggaat tgatttccct atactgatca tcaacccagc tgccggcata actgctacca
    45601 caaccattaa agcctttcca aatttttgcc aaaactcaaa actaaatatc tttttcattc
    45661 cgtttagctc ctttacgcaa tcggtttcgt taaacgtatt atagcgtgcg ttttcttttt
    45721 tgtaaatgct ttatttttta tttttctgtc tataccattc tataaaacct ataatacgtg
    45781 tgttcccttc tataattttc tcctaaaaat ttattttttt aagctttttt ctatgaaata
    45841 ttttcttttg tctattgact tgtgcaatcg gttgcgttta ttatgaacgt ataaaacagc
    45901 tcattaggag gagaaaaatg aaacagatca aacgactatt tgctattgat ccatggaaaa
    45961 tcagcacgac acaattagat aaaaaaaatc ttcgactgca agaatcttta acaagtattg
    46021 gaaacggtta tatggggatg cgcgggaact ttgaagaaac ttactcaggg gaccaccatc
    46081 aaggtactta tttggcgggt gtctggtatc ccgataagac acgtgtcggc tggtggaaaa
    46141 atggttatcc agaatacttt ggaaaagtga tcaacgcctt gaactttatc gcgatagata
    46201 tttcgatcaa cgatcagctg atcgacttgg cttctttgga accagaagac ttttactggg
    46261 aattagatat gaaaaatggt gtattatctc gtacattcac aatcactact tctactaata
    46321 aagtacgcat ttccttcgaa cgttttctga gcattgtcaa aaaagaatca gcttatatct
    46381 atttaactat agaaatgctt gaaggtagcg gaacagtcaa actcgtatca aaattggatg
    46441 gaaatgttca aaacgaagac agcaactatg atgaacattt ttggaatgag attgatcgtg
    46501 gaactataga agaaatcggc tatttgacga ctaaaactat tccaaacaac tttgggattg
    46561 aacaatttac tgttactgca gcaatgcgcc atttcgttaa tggaaaatca gtcatccctg
    46621 actatcacga agatacttta gcattacatg gttgcttgtc tgcagaatta tctcaaggtg
    46681 agacatggtc agtggaaaaa gaaattatcg ttcttactag tagagatatt ccagaagcgc
    46741 agcaagcaga aaaagctgtc tcagaattaa cgaaccagac aaacaattat atccaagcaa
    46801 aagaagagca aacagcggct tgggcagaac gatggaagct tgccgatgtg gtcatcgaag
    46861 gagacgaaga agcacaacaa ggtattcgat tcaatttgtt ccaactattc tctacttact
    46921 acggcgaaga tgaacgattg aatatcggcc ccaaaggatt cacaggagaa aaatacggcg
    46981 gagccactta ctgggataca gaagcgtatg ctgtccctct ttatcttgct ttagccaaac
    47041 ctgaagtaac taagaatctg ctgaaatatc ggcataatca actgccgcaa gcaatccaca
    47101 acgctcagca acaaggatta aaaggcgcgc tttatcctat ggtcaccttc actggtgtcg
    47161 aatgccataa cgagtgggaa atcacattcg aggagattca ccgaaatggc gcgattgcct
    47221 atgcaatcta caattatacg aattacaccg gcgatacgga atatttgaaa aatgaaggac
    47281 tggaagtttt agcagaaatc gcacgcttct gggcagaccg tgtccatttt tcaaaacgag
    47341 caaataaata catgatccac ggtgtgaccg gcccaaacga atatgagaac aatatcaata
    47401 acaattggta tacaaatacg atcgcagctt gggtcttgcg ttacacgcga gaaaattatt
    47461 taacttatca aaaagaagct gctatcacta tcagcgaaga agaactagcc aaatggaaag
    47521 atatcgcaga gaacatgtac ttcccagttg acgaagaatt aggaatcttt gtccagcatg
    47581 acacattctt agataaagat ctcatgcctg tatccgatat tcccacaagc gatcttcctc
    47641 tgaatcagca ttggtcttgg gacaaaatcc ttagatcttg cttcatcaag caggcagatg
    47701 tactacaggg gatttatttc ttcaatgata cttttacaaa agaagaaaag caaaaaaact
    47761 ttgatttcta tgaaccaatg actgtccatg agtcttccct ttcgccaagt atccattcga
    47821 ttttagcagc agaattagga atggaaagca aagctgtaga aatgtaccag cgaacagctc
    47881 gcttggattt ggataattac aataacgaca cagaagacgg cttgcacatc acttccatga
    47941 ctggtagctg gttgtcgatt gtccaaggat ttgctcaaat gaaaactgcc catgatcagt
    48001 tgagattcgc accatttctg ccaaaaactt ggaaagctta ttctttccat atcaattatc
    48061 gcggacgttt attgttcatc tcagtcacag atgaacaagt tactttcgag ttattagaag
    48121 gttctcctct agaaatttac gtctatgaac agtcttattc tttagcggat cgtctagaaa
    48181 taacgctaag aaaggaggaa gcaaatgttt aaaggggtat tgtttgattt agacggtgtc
    48241 attaccgata ctgctgaatt ccattatcgt gcttggcgaa agcttggtca ggaaatcggc
    48301 attacgatcg accacacatt caacgaacag ctaaaaggcg tcagccgaga agactcactc
    48361 tctttgcttt tagcttatgg cggaaaagaa cactcttttt caaaggaaga atttgcagaa
    48421 ttagcgaaaa gaaaaaacga ttattattta gagatgatcc agacgatcga accaaaagat
    48481 gtcttccccg gggtcgtgcc tttactggat tctttaaaag aagaaaaaat caagattgct
    48541 cttgcttctg caagtaaaaa cgggccattc ctacttgaaa aaatgggtct tacaccttac
    48601 tttgatgcta ttgccgaccc ggcagaagca acaaacggaa aacctgcgcc agatatcttc
    48661 ctccttgcag caaaagctgt cggactaaaa gcagaagaat gtatcgggat cgaagacgcg
    48721 caagccggta tccaagccat cctctcaagt ggcgctcaac caattggcgt gggacgtgct
    48781 gaagaccttg gagaggagat cccgcttgtc cctgatacga cttttcttac gatcgattac
    48841 ttgaaagaaa agtggcatga ccatggataa tccagagatc tccgtcgtac cagttccaga
    48901 gactgaaata aagaaaatca cattgaagaa cgactactta gaagtcgttc ttctcaatta
    48961 cggtgcccgc ctgcaccaaa tcttcgcacc agacaaagaa ggaaaatcag aaaatgtttt
    49021 attgtcttac gatcgtttcg aagatgttct aacagacaaa agcttttttg gagcaactgt
    49081 cggacctgta gccggaagga tccgggatgc ttcttggggt gagcatagat tggagaaaaa
    49141 ctgcggatca caccatatcc acggtggcac gaaaggctgg tctttccaat tttgggaagt
    49201 agaagttttc aaaactccat catcaatagg tgtggtcttt tacttaaaag atgaattttc
    49261 tacctatcca ggaccaatca ctgctacgat cacttaccgt ttaacaaaaa acgaattaga
    49321 gatgacaacc tctgctagta gccttgttga aaccatctgc aatccgacca accatgccta
    49381 cttcaacctt tcaggaaatg gaacaagaga catctatgaa catcagttaa cggtcttttt
    49441 agatggtgtg cttgaattag atcaagaaaa actgcctact ggaaattgga caaaaaaaga
    49501 aaaactgcca atcgacttta gaaaatcccc aacactgcaa gagatccttg catgttatcc
    49561 agatggacta gatgatgtat ttcttttgca tcatcctagg ctttccaaaa cttccttaca
    49621 attattcgag aagcattctg gtcgccaaat gactatagca acttctaata aaagtatggt
    49681 attattttct acgactggat tcgaagctga tttctctgtc aatggaaaac agatgcattc
    49741 aaactacgga ttagcaatcg aaccgcaaga aatccctgat atcgttcatt tccccaaatt
    49801 tggatcgatc aacctccatc ctggtcaaga acggatcagt cagacgattt atcggttctc
    49861 tgcacaataa caagagaaag gtgtttttat catggctatt accgtaaaag atgtggcgaa
    49921 aaaagccggt gttgccacct cgaccgtctc tcgtgtcatc aacgatcatc ctagtatttc
    49981 cgagacaaca aagaagaaag tccgaaaaat tatggatgaa ctaggttatg ttcctaacat
    50041 gactgcccgc aatctaggaa aacgcatttc cagtgccatc ggcgtaatct taccccctct
    50101 tgattcaaaa gagcggatcg gtaacccatt ttatcttgag atcatggaag caatcaacga
    50161 agaagcgcgg aattatgata tgactacagc aatcgctact gctaaaaatt ttgaattgct
    50221 gttagagaac gtccagcgta tgcatttaca aaaacaagta gatggtttta ttctagtgta
    50281 ttcagatagt caagatactg tcattgatta tttataccaa aaccacatcc ctttcacttt
    50341 gatcggacag ccttatcatc atgagaacga aatcgtttat gtagataatg ataaccagct
    50401 tctaggtaaa caagcaacag aatttttgat ccagaatgga cataagaata tcctgtttgt
    50461 gacaaacacg actcatgaaa gtttgtattt cgaacgatat ttcggttatc aaaaagcaat
    50521 gatgatggct ggtcttcctg cgttatccag tgtagtacta gagcatccgg aggattatct
    50581 gtcctttgag aaaacgttga aagaaaacga agccacagca ttggtggtca ttgacgatat
    50641 cttcgccctt cgcacgatgc agttggcgca aatgtatggc tatgtcattc cagagacact
    50701 ctccgtcatt agcttcaaca actcgatctt ctcaacatta acacaccctt accttacaag
    50761 tatcgatatc gatatctccg aattaggacg tgtcgctatg caaaagctgc gcgaattgat
    50821 ccatgaagaa ttgagcagtg gcgtacgttt ggtcatccct catcgcttga tcaaaagaga
    50881 gacagtcgtt cctttagaaa acccatacta aatagctgac tcactaaata cgctgaccat
    50941 ttatcctatg gtcagctttt tatgtaaaag aagatactac ttctaacaca ttgtttatct
    51001 gtaaaaaaga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    51061 aaacggcgga agcagaagca actccttcgg aaataagctg aaattcacaa aaatttaaaa
    51121 agcaattttc ttgagtttct tcttatttct tggagttaaa cgcttctgtc ccagcctctt
    51181 ttttccttcc ttcaattttt tacacgtcga cgattcaata aaaaaccgcc taatattgta
    51241 aagacaggtg caagaatcga gaaaaaggcg aatggcaagt aatgcaacgc gctaactttc
    51301 atcgttccca taatgaatgt gccgctgact ccccacggta cgagagaatt gacggtcgca
    51361 cctgaatccg ctagtgttcg tgtcaaatag gtttttgata agccaacgtc atcaaaagaa
    51421 cgcttgaatg tttctcctgg aagaatgatg gacagatact gttctccaac gatcagattg
    51481 attccgatac agctcaaggc agtaaacccg actaaacgag aaggtcggtc catcttttct
    51541 tttaattctt gaacgatggt atcaacgatc agatatttga tcagtaaccc acctaatgcc
    51601 aatgcaagta aaatcaaact agcagaacct aacatactca tgatcccgcc tcgagaaagc
    51661 agttcatcta gctttggatc aggtgtattt gcgacataac cattcatcaa gatgtctgct
    51721 gcttttccga ccgtcaaact tttctcatgg ataaaagaaa gaacgagagc agctgtcgat
    51781 cccgctagta atgtagggat agccggaatt tttttgattg cccccccaaa taaaataact
    51841 agtggaatca atgtccaagg agagatccaa aagctcgctt tcatgttttg gatcatttca
    51901 ttgatactag ctagatcggc tgaatgactg ttatgtccta atatcgtata aaaaatcaac
    51961 gaaaggacga atgctgggaa atccgtataa cgcataccag cgatatgttc gaatagatta
    52021 actcctccaa tacccgctgc caagttggtc gtatctgata aaggcgagca gttattccct
    52081 aaaaaggcac cggaaacgac tgcgcctgta gtcattgcat cattgaatcc aagtaaatga
    52141 ccgatcccca aaaaagcaat tccaatcgtc gaaatcgttg taaatgaact gccgacagtc
    52201 actccgacaa ttgcacaaac aagaaatgct gtcggtaaaa agaaacgcac agaaacaagt
    52261 ttaaatccat aaaccataat cgtagggatg gttccagata aaatccatga agcaactaag
    52321 acaccaatca aaagaaaaat caggattgga atgatccctg gagtgattcc tttgatgatc
    52381 ccgtcatgga tctcatccca tgtgaacttt ttaaatctgc cataaaacaa caaacacatg
    52441 aaagctgcaa ggatcgggat atgtggcgag agctggaatc cgatgatcag tactcctagg
    52501 agtgccaaca acacgatcaa tacagcgata ctttctttta aagaaatatt tttattcatc
    52561 gtcgatctcc tatttcaaat gaaaaggccc tgccatgaaa aaactattca cttggcagga
    52621 cctcctacta aatcagcgac aaaacgtcgg ctgaaagact tattttttta tttttcttct
    52681 aaactttttt ctacctcaat cccccaagaa tctttcttga agtgattgat gatcaatgga
    52741 ataacgaaca tgaccactgt gatagctgct actaataatg catcactcaa tgtcgctgta
    52801 cctaatgtag caaatacgac aacgatgata gagaagatca gcatgcagct gactacccaa
    52861 gctaatccgt ttccgttttt accaattcgg taaggacgtt cgaattctgg atgtttctta
    52921 cgcattttaa gcaatgaaac agcaatcaaa atgtacacga tacaataaat aacagttgta
    52981 gcatttgtaa gtgtcaagaa tacagcactt acgtcatcca ttacaccata aagcaaagca
    53041 aataatgaaa taacgattga ttgtgttaga acgacatttc tagatacgcc gtatttgttt
    53101 tctttatgga atccgaattt tggtggaagg aatccttcac gagctacttg gatgattgtt
    53161 tttgatggtc cagtaaccca agctgataat tgtaaaagca caccaataaa taccatgaag
    53221 ctgaagatat ttccgatcac ttctggtaag cctaggattt gacagtcaat caagataggc
    53281 tgcgtgatat ttgctaattc catttttcca tctggtacga catttgctac aagcatcgca
    53341 ttgatgacat tcaataaaac taatccgatc aaagcgataa atacgccttt tgtataattt
    53401 tttgttgcgt ctttcaaacg aggcatgtaa acagaactca tttcgatccc aacaaaaata
    53461 aatgtgatac cagctaagta tttcaatgaa tcaatatgtt ccaagtcagg gaaagctttt
    53521 gaccatgaaa agtcacctag atagccgttt gagactagtc cgactttgaa ggctgccaaa
    53581 acacctaaaa cgaacatgat gactactggg atatataccc ctagccatac accgatgttc
    53641 ccgccgactt ttgccatatc gaatttcaag ttcaagatcg tgatgatcca gtagataact
    53701 aaaatacaac ctaaaacgaa ccagtgatta ttgccaagtt ctacattacc aaatgtgttt
    53761 cctaacaatg gtcctaaagt agaagcgacc attaccatac ctgggaacat ttgcacccat
    53821 aatagccatg caacgacaaa tccccatttg ctgcccagtg ctgtttttac ccataactga
    53881 ggaccgcctt cttgaggaag catcgtggaa agctcaccgg aaaccattga tatcggaccg
    53941 gcaaaaaaca aaactgcaaa aattgaataa aaaatcaatg tccaaccgac tgcggctaac
    54001 gtaggaatac tccgaaccgt tgcacacagt gccattgtca gaccgataaa ggtcccaaga
    54061 cccattttac ttacttcaga tttactcacc gttgacactc tccttgattt tttggataaa
    54121 ataacggtgt ctttgaagta gtttcagcaa taaacgaaac aattcagcga atatttgagg
    54181 ggattctttg agtttattgc ttgaagggtt tcttcaaaga caacctcaaa acaaagggat
    54241 cgaagagctt aggtctcccc ttgctcttca gatccaaaca tgcgtcagaa acagttagta
    54301 ttcaagctgt tttctaacat gattaccttg cttattttgc ttcgcttgcc aataattggt
    54361 ctgcgtagat tttttccaat ttttcttgaa gagctgcttt gattttttca gcatattctt
    54421 caaagtgttc ttctttgttc atgtatggtg tcattacgct ggcacgcaat acagttactt
    54481 ttccggcacg gttccattct tcatctgaga atcctagttg gttcacaaat tgtaatgggc
    54541 tgttgccata gtctgggata gcaaagtcag tatgtgaagt taagaactca ttaccgtaaa
    54601 tgcttccttt cacgtatgaa gaataatcat atacgtcatg gttcaattta ttcattgcaa
    54661 ctaagtcatc gttgcctttt tctttgaata catagtctac catattgaaa tctggataag
    54721 ttaatggatg aacttcgatt tctttgtctc ctactttaaa tgacaagtca ttcaagaagt
    54781 tgtagaaacg atgtgcacct tcgattgatg cacccattaa tttaccatat cctgtgacat
    54841 tcaaaggtaa gacatggtgt gctgcccaaa cgctggctgc tgttgcccct gcttttgaac
    54901 cttccaagat ataagcccca agtaatgctg ggatatctgc gcctttttca aatacatatg
    54961 tcgcaaagta agagataacg tctctcatgc ggatatcttt gatgacgata ccaccggcag
    55021 aatatggaac atagcccatt ttatgtgggt caatcgttac agattctgct tcttcgattg
    55081 ctttatatgc actgtgtact tcttctaaga tataatcttt gttttctgta aagacattgt
    55141 atttgtaatg aacatctttt aaatcttcaa atggaatgaa gttgttgtct tcgtctaaga
    55201 aaatcgcacg gccgtatccg ccataagcag catctacgtg taagtagaag taaataccgt
    55261 ctttttctaa tacgcgacgc aatgcaacga ttttatcgat accgtcgatt gctccttctt
    55321 ctgttgatcc tacaacaccg actacaccta ggattggtgt tttttcagct gctagaccac
    55381 gaacgatttt ttcaagttcg ttgatgtcca tgcgatagtt gtggtcaact ggcactggaa
    55441 tcacttggtc taaaccgata ccgatgatgt cggcagcttt tagccatgaa tagtgtttag
    55501 tttgtggaac caaccatttt cctaattttt ctaaatgttt tccgctacgt gctgagtgag
    55561 ctttgatttc gtcgattttt tctgggacgc tgtctaacag attcatgatt tcttctgttg
    55621 acaagttcat taattcccaa tcgctttttc cagcaactag ttcaggtgtc acttctttca
    55681 ttgcaagcgg caatgatttg atgttgcggg cataccaaag tccttctaag tttgctaaag
    55741 aaccatcagc aacgatgtgg ccccagccat ctttatagct cattaatttt gcaaattcca
    55801 ttcctacttc ttcttccatt tggcttgttg caggagaaga ttcataggca acgttattac
    55861 cattccatag catagcaaaa ttgtacgcta gtaaagatgg catcaatgtt tcagagttca
    55921 tatgacccca gtaacgtccg gcattatgcc aaggaacgga atgggtacgc atccgcgctg
    55981 aaatttctga tagaacatcc tttgttttat tcacagtgtg ttcaaaacta gcactgcttt
    56041 tttcttctgg cgtaataata ggcatgtctt gaggcatgta gttttgacgc cagcctaaat
    56101 gttcatccac caattcattc aacaaagctt tatagatttg gccgttctca gctttgtccc
    56161 caatgaatag ggcatttagg tttagatctt tcgacaatga ttcactcata gtgaaaccct
    56221 cctaaaaaaa tatttaaatt ttgtcgagcc ctacattaca cctgttcttc tattctgtaa
    56281 actaagtttt ggcctgattt ttaatcatat tttaatatgt atcaattatc cgaattgttc
    56341 acacttttga aataattaaa aaaaacgagg gaatttacaa atgtaaactc cctcgcaaag
    56401 attgtattaa cgacaaccag cgttctattt taggatgggt ttcaaaattg gaatgttgta
    56461 atagtatttc cctttttcaa ggtaaaaact tactaaattc taatcaatta ctttggccaa
    56521 aaagtaattt ttcttacctt ttcgaataac cacaaactta ccatcgaatt catcggatgg
    56581 atttatgaca aaatttaaat cggtaacgcg gtcaccgtta atacttatag ctccgtttga
    56641 aacatcttca cgtgcttgac gtttagatgg ttcaattttt gtggaaacaa gcagttccac
    56701 gatattttca ggtgtgcttg aaatttcaac gttcggcatt ttaccgaatc cttgcgcgat
    56761 ttcttccgca tttagttctt taatatttcc agagaacaat gcttgcgtta ttttttgcgc
    56821 ttctttcaag tcttcttcac tatgcacaaa tcttgtaact tcttctgcca aacggcgttg
    56881 tgcttcacgt ttctcaggtt ctgtctctac ttttttcgct aagtcttcga tttcttcttg
    56941 agacaagaaa gtaaagaatt tcaagtattt cactacatcg cgatcatctt gattcaacca
    57001 gaattggtag aactcaaatg gtgaagtttt cttcggatca agccaaacgg caccgcctgc
    57061 agtttttccg aatttcgttc cgtcagcctt cagcatcaat gggatcgtta aaccgaacgc
    57121 ttctgcttct ggtccttcta attttcggat taggtctaat ccagctgtga tatttcccca
    57181 ttggtctgct ccaccgattt gcaattgcac atcgtatgtt ttatgcagat gcaaaaagtc
    57241 gatagattgc aggatttggt aagtaaactc tgtaaatgag attcctactt ccaaacggct
    57301 ggcaacgata tcttttgcta acatcgtgtt gatgttgaag tttttaccgt agtctctcaa
    57361 aaattcaagt aaagagattt ttgacaacca gtcgtagttg ttcacaaatg tgatatttgc
    57421 atctttacca aacaattttc tcatttgatt ggaaagtgcg tccacgttat gttgcacttg
    57481 ttccatcgtt tgcaacacac gttctgtttt gcggccgctt gggtcgccga tcgttcctgt
    57541 tccgccgcca atcagaatat atggatgatg gcctgccaat tggaatcttt tcatcatcat
    57601 aaatggaatc aaatgtccga tatgcatcga atcaccagtt ggatcaacgc cgcaataaag
    57661 tgaaatgctc ttttcttcaa cgagctcgcg aagtctttct tcgtttgttt gctgattaat
    57721 ggcgtcgcgc caagttaatt catcaataat attcatttta ctgacctccg tgtagttttt
    57781 ttatgaaagc aggaacctgc tagcatatgt aattaattat ttcttcagga taggatagga
    57841 aataaaaaaa gtcccttggc atataagcca agggacgaaa tctcgcggta ccacccaatt
    57901 tgtatgtcta gatatccaac atacctctcg aacatttaac gctgtcgcgt ggcaatcact
    57961 gccaaagact cctgaaatgt aattcgcttt aaagcatgta ctggtttgca gcgaccacca
    58021 gctttctgaa acattggctt taacaactac ttcgtttcga tcttcgtctt gttattatta
    58081 atatgtgtct atcatagagc gcaacttttt ctttgtcaac agaaaaagga tatttttttt
    58141 aaattcctca ttttttcttt tttgaatccg ctctaattcc gaacatttta ttttcaatta
    58201 ttgttaaaag aaataacttt ttctgtattt tttctgcaat ttatcgagaa gtcactttac
    58261 tttgcctctt attctttctt cgttacaata aggaatggga caagtaaaaa aatgaaaaag
    58321 caagggacga ggtatatgga aaaaaagcaa aaaattattt taggagccac ttctgcttta
    58381 actatcgtta ttttaattct aagtttgttt tttgtcatcc gatcatctac aaaaaaagaa
    58441 ccaatcattc ctgaaaaaaa aataacagaa aaagcaaaag aaccgacaga tgataagcaa
    58501 caactagtta ctcaagcaaa aaatctggct caaagctacg attatgacca agcgattgcg
    58561 ttattggaaa aagatagtaa gaacggatct actgaaacac aacagcttct tcaaacacta
    58621 aaaaaggaga aagaacaact gatcgactgg tctgatccta ctcagatctc tcatgtcttt
    58681 ttccacagct tgatcgtgga cccgcaaaaa gccttccact ctcaacaggc acaaggatac
    58741 aaagattata tggtgactgt tgaagaattc aaccgttcga tcgaacaact ttatcaaaat
    58801 gattttgttt tagttaattt gaatgatttg atccaaaaag acgaacaagg aaatctttcc
    58861 tttaacgggc ttgcgctacc tgaaggaaaa aaaccattgg ttctttcaca agatgatgtc
    58921 agctattatg aatatatgga taattccggt tttcctagcc gattggtcgt atcaaataac
    58981 aatgaaatca aaaatgtcta taaagagaaa gataaagaag aaatcggtga ctttgacatg
    59041 gttcctctga tcgatgcctt tgtcaagaaa catcctgatt tttcttatcg aggcgcaaaa
    59101 ggtaccttgg ccctgacagg ttacaacgga gttttaggtt atcgaacatc aaaatctcaa
    59161 tatggagaca atgaaaaaac aaaaaaagag attaaagaag ctaaaaaagt ggcggaacag
    59221 ttgaagaaag acggctggag ctttgcttcc catacatggg gtcacttgaa tatgactcaa
    59281 gcttcactag aagatgtaaa aaaagacaat gaattgtggc agcaagaagt tgcacctatc
    59341 ctaggaaaaa caaatattct gatttatcca tttggtgcag acatcagcga ctggcagcct
    59401 tattcagcag aaaatcaaaa atttgcttac ttgaagagtc aaggtttcga tattttctgt
    59461 aatgtcgatg cttctacacc agcttgggga caattaggta cggatttcta tcgaaatgct
    59521 cggatcaata tcgatggcat tcgttttcaa tctgatttag acggaaaaaa tcctattctt
    59581 gatccattca tcaatgtcca tgatgtctat gacaaagaag cacgcgaatc tgcttgattt
    59641 tacgtcattt atgaaccaaa aaagccgaac tgacatttta tcgtcagttt cggctttttt
    59701 atgctttatt tcttcttcgg tgcgattccc ttgatcagga cttctgtcca ttctgctgta
    59761 tatggaagca gttttgcgta tatctccggc ttagaaattc cttctaccat tgcttgaaaa
    59821 tagaggatca agaactcatc cgaatatttc aaatccactt ttccttcttt ccgccctcga
    59881 tggaaaagat caagcatgat actgaaactt tcttgcgtat acgcatccat cgcgtcagaa
    59941 aattcttttt tttctttttt tgtatagtat gtcatcaaat cgatataaaa ttgtttgttc
    60001 actcgattga gataacggat tttgttttca ctcatggcaa tcagtgtttc ttcaaatgga
    60061 agattttccg caatcaacgc tttcgcttct tgccctaaat cattcataaa tgcaaaaaat
    60121 acttcataaa tcagcccttc cttgctgcca aaatatttaa aaatcgtcgc tttacttacc
    60181 tgagcgttct cagctacctt atccattgtc actccagcgg ttcctatgtc tgtgttcatc
    60241 aagtcaaaag ctgcttgtaa aatctctttc tttttctctt gtgctctctt ttcaaaaccg
    60301 ttcatttgta gagcctcccg taattttaaa cttttataat atatatagtt caaatttatt
    60361 ctgaggttta ttataactat ctattgagaa agtatcaagc tagcaattcc ttgtttatga
    60421 attca
//
LOCUS       DADVXV010000007        55296 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.007, whole genome shotgun sequence.
ACCESSION   DADVXV010000007 DADVXV010000000
VERSION     DADVXV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.007"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            28..885
                     /locus_tag="KB969_000380"
     CDS             28..885
                     /locus_tag="KB969_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBB6868395.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1000..1920
                     /gene="pstC"
                     /locus_tag="KB969_000381"
     CDS             1000..1920
                     /gene="pstC"
                     /locus_tag="KB969_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBB6868396.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            1920..2804
                     /gene="pstA"
                     /locus_tag="KB969_000382"
     CDS             1920..2804
                     /gene="pstA"
                     /locus_tag="KB969_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBB6868397.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2819..3625
                     /gene="pstB"
                     /locus_tag="KB969_000383"
     CDS             2819..3625
                     /gene="pstB"
                     /locus_tag="KB969_000383"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6868398.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3641..4399
                     /locus_tag="KB969_000384"
     CDS             3641..4399
                     /locus_tag="KB969_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBB6868399.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4412..5089
                     /gene="phoU"
                     /locus_tag="KB969_000385"
     CDS             4412..5089
                     /gene="phoU"
                     /locus_tag="KB969_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBB6868400.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5327..5626
                     /locus_tag="KB969_000386"
     CDS             5327..5626
                     /locus_tag="KB969_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868401.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5652..6359
                     /locus_tag="KB969_000387"
     CDS             5652..6359
                     /locus_tag="KB969_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6868402.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6356..7123
                     /locus_tag="KB969_000388"
     CDS             6356..7123
                     /locus_tag="KB969_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBB6868403.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7223..8791
                     /gene="liaX"
                     /locus_tag="KB969_000389"
     CDS             7223..8791
                     /gene="liaX"
                     /locus_tag="KB969_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBB6868404.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9088..9408
                     /locus_tag="KB969_000390"
     CDS             9088..9408
                     /locus_tag="KB969_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBB6868405.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9408..9758
                     /locus_tag="KB969_000391"
     CDS             9408..9758
                     /locus_tag="KB969_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBB6868406.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            9925..10863
                     /locus_tag="KB969_000392"
     CDS             9925..10863
                     /locus_tag="KB969_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBB6868407.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10878..11708
                     /locus_tag="KB969_000393"
     CDS             10878..11708
                     /locus_tag="KB969_000393"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBB6868408.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11752..12777
                     /locus_tag="KB969_000394"
     CDS             11752..12777
                     /locus_tag="KB969_000394"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6868409.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12792..13730
                     /gene="galU"
                     /locus_tag="KB969_000395"
     CDS             12792..13730
                     /gene="galU"
                     /locus_tag="KB969_000395"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6868410.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13855..14295
                     /locus_tag="KB969_000396"
     CDS             13855..14295
                     /locus_tag="KB969_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBB6868411.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14298..14900
                     /locus_tag="KB969_000397"
     CDS             14298..14900
                     /locus_tag="KB969_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6868412.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(14968..16074)
                     /locus_tag="KB969_000398"
     CDS             complement(14968..16074)
                     /locus_tag="KB969_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6868413.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16284..17285
                     /gene="ccpA"
                     /locus_tag="KB969_000399"
     CDS             16284..17285
                     /gene="ccpA"
                     /locus_tag="KB969_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBB6868414.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17588..19933)
                     /locus_tag="KB969_000400"
     CDS             complement(17588..19933)
                     /locus_tag="KB969_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6868415.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20212..21114
                     /locus_tag="KB969_000401"
     CDS             20212..21114
                     /locus_tag="KB969_000401"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBB6868416.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21327..23102
                     /locus_tag="KB969_000402"
     CDS             21327..23102
                     /locus_tag="KB969_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBB6868417.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23359..24576
                     /locus_tag="KB969_000403"
     CDS             23359..24576
                     /locus_tag="KB969_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6868418.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(25023..26609)
                     /locus_tag="KB969_000404"
     CDS             complement(25023..26609)
                     /locus_tag="KB969_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBB6868419.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            26860..27084
                     /locus_tag="KB969_000405"
     CDS             26860..27084
                     /locus_tag="KB969_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBB6868420.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27226..28977
                     /locus_tag="KB969_000406"
     CDS             27226..28977
                     /locus_tag="KB969_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6868421.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            28977..30761
                     /locus_tag="KB969_000407"
     CDS             28977..30761
                     /locus_tag="KB969_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868422.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            31219..32070
                     /locus_tag="KB969_000408"
     CDS             31219..32070
                     /locus_tag="KB969_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6868423.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            32167..34053
                     /locus_tag="KB969_000409"
     CDS             32167..34053
                     /locus_tag="KB969_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6868424.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(34094..34996)
                     /locus_tag="KB969_000410"
     CDS             complement(34094..34996)
                     /locus_tag="KB969_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6868425.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            35226..36629
                     /locus_tag="KB969_000411"
     CDS             35226..36629
                     /locus_tag="KB969_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6868426.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            36626..38062
                     /locus_tag="KB969_000412"
     CDS             36626..38062
                     /locus_tag="KB969_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6868427.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            38207..39133
                     /gene="trxB"
                     /locus_tag="KB969_000413"
     CDS             38207..39133
                     /gene="trxB"
                     /locus_tag="KB969_000413"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBB6868428.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            39346..41073
                     /locus_tag="KB969_000414"
     CDS             39346..41073
                     /locus_tag="KB969_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBB6868429.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            41089..41439
                     /locus_tag="KB969_000415"
     CDS             41089..41439
                     /locus_tag="KB969_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBB6868430.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(41523..42383)
                     /locus_tag="KB969_000416"
     CDS             complement(41523..42383)
                     /locus_tag="KB969_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBB6868431.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            42475..42903
                     /locus_tag="KB969_000417"
     CDS             42475..42903
                     /locus_tag="KB969_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6868432.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            43065..43241
                     /locus_tag="KB969_000418"
     CDS             43065..43241
                     /locus_tag="KB969_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBB6868433.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            43268..43714
                     /locus_tag="KB969_000419"
     CDS             43268..43714
                     /locus_tag="KB969_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBB6868434.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(43870..45249)
                     /gene="brnQ"
                     /locus_tag="KB969_000420"
     CDS             complement(43870..45249)
                     /gene="brnQ"
                     /locus_tag="KB969_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6868435.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            45955..46926
                     /locus_tag="KB969_000421"
     CDS             45955..46926
                     /locus_tag="KB969_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBB6868436.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            46950..49142
                     /locus_tag="KB969_000422"
     CDS             46950..49142
                     /locus_tag="KB969_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBB6868437.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            49159..49635
                     /gene="ybeY"
                     /locus_tag="KB969_000423"
     CDS             49159..49635
                     /gene="ybeY"
                     /locus_tag="KB969_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBB6868438.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            49619..50014
                     /locus_tag="KB969_000424"
     CDS             49619..50014
                     /locus_tag="KB969_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBB6868439.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            50029..50928
                     /gene="era"
                     /locus_tag="KB969_000425"
     CDS             50029..50928
                     /gene="era"
                     /locus_tag="KB969_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBB6868440.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            51071..51883
                     /gene="recO"
                     /locus_tag="KB969_000426"
     CDS             51071..51883
                     /gene="recO"
                     /locus_tag="KB969_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBB6868441.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            52267..53184
                     /gene="glyQ"
                     /locus_tag="KB969_000427"
     CDS             52267..53184
                     /gene="glyQ"
                     /locus_tag="KB969_000427"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBB6868442.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            53186..55261
                     /locus_tag="KB969_000428"
     CDS             53186..55261
                     /locus_tag="KB969_000428"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBB6868443.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        17912 a         9926 c        11770 g        15688 t
ORIGIN      
        1 atactttagg attaaaggag atttctaatg aaaaaactta aattattctt accaataata
       61 ggattagcca ttcttttatc aggctgttca aagtggattg atcgaggaga atccattacg
      121 gctgttggct cttctgcttt acagccttta gtagaaacag ttgctgaaac ttaccagaca
      181 gaaaatcctg gaaaattcat caatgtacaa gggggcggaa gcggaactgg tttgtctcaa
      241 gtacagtcag gagcagtcga catcggaaac tctgatttgt ttgcggaaga aaaatcgggg
      301 atcgatgcct cagcattagt cgatcatcga gtagcagttg ttgggatcac tcctattgtg
      361 aacaaggata ttggcgtaaa agacatcagt atggaaaacc tgaaaaaact atttacaggc
      421 gagatcaaaa actggagtga agtcggtgga aaagatcagc cagtagttat attgaaccgc
      481 gcttcaggaa gcggaacccg tagcacgttt gaaaaatggg tattggacgg agaaacagct
      541 gttcaggcac aagaacaaga ttcaagcgga atggtgcgcc agatcgttgc cgacacaccc
      601 ggtgcaatca gctatgttgc tttttcttat gtttccgatg atgtagatac gttgaatgtt
      661 aacggtgtag aaccgacaga tgaaaatgtg acaacgaaca aatggacgat ttgggcatat
      721 gagcatatgt acacaagaga tcatccaaaa aaactgacaa aagaattttt agactatatc
      781 ttatctgatg aagtacaaga taacatcgtt ggagaactag gttatatccc tgtttctcat
      841 atgaaagtcg aacgtgattg gcaaggaaat atcgttaaag agtaatcttt acacaaaatt
      901 tacaaactta gctaaacttt tacatgttat taaaaccaaa ttgatgttca atttgtacac
      961 tgagtgagta tgttaaacct gattaagggg gagtcatctg tggaagatgt gaaaaaagta
     1021 ttattaacaa aatcaaaacg ttcaaaaatg gaacagcgtg gaaaattcat cagtttttta
     1081 tgtatcgcgc tgatcgtgtt ggttgtatta tctatttttt attttgtagc tagtaaagga
     1141 ttggccacct tttttactga taagatcaat gtatttgatt ttctgtttgg tacagattgg
     1201 aatccaagcc aaatcggagc aaatgggaaa ccaatggtag gggcattgcc tatgatcaca
     1261 ggttcgttta ttgtgacctt tttatctgct atcgttgcca cgccatttgc cattggtgca
     1321 gcagtattca tgacggagat ctctcctaaa aacggaacga agatcttaca gccggtcatc
     1381 gagctgcttg taggtattcc ttctgtcgtt tatggtttta tcggtttatc agttatcgtg
     1441 ccttttgtca gaagtatttt tggcgggaca gggtttggta tcttagctgg tacatttgtg
     1501 ttgttcgtta tgatcttgcc gactgtcaca acgatgactg ttgatgcatt aaaggcagtg
     1561 ccacggcact atcgggaagc ttcattagcg cttggtgcca caagatggca aacaatctac
     1621 aaagtcgtgc tacgagcagc cgtgcccggg attttaacag cagtcgtttt tggtatggct
     1681 cgtgcgtttg gtgaagcctt agctatccaa atggtcatcg gtaatgcagc attgatgcca
     1741 acaggactta ctactcctgc ttctacattg acgtccatct taacaatggg aatcggaaat
     1801 acaatcatgg gaacagttga aaataatgtg ttatggtcat tagcgctgat cttgctattg
     1861 atgtcattat tctttaatat cgtgatccgt atgattggga agaaaggaga gctgaaataa
     1921 tgaacgcaaa acgctcagat aaaattgcta caggtgtttt atatatagtt tcggggatca
     1981 tcgtattgat tttagcagct ttactacttt atatcttagt tcggggaata ccgcatattt
     2041 catggtcctt cttgaccgaa ccttccaaag cctaccaaga aggcggtgga atcgggatcc
     2101 agctatttaa ctcgatttat ttgcttttga tcacgatgat catcagtttt cctatttctt
     2161 taggtgcggg tatctatctt tcagaatatg ctggaaaaaa ctggctaaca gatgtgattc
     2221 gcacgtcgat tgaaatcttg agctcgttgc cttctgtcgt tgtcggttta ttcggtttct
     2281 tggttttcgt tattcaattc cagtatggtt tctcgattat ttctggtgca ttggctttga
     2341 ctgtattcaa cttgcctctt ttgactagaa cagttgagga gtctttacaa gcggtccatt
     2401 acacacaacg agaagcagga ttggccttag gtttgtcacg ctgggaaaca gtgataaaag
     2461 tggtggttcc agaagcgaca ccagggattt tgactggtgt gatcctaagt tctggaagaa
     2521 tttttggtga agcagctgca ttgatctata cggctggaca aagtgcacct gcgttagatt
     2581 ttacgaactg gaatccatta agtgtttcaa gcccgatcag cattttccgt caagctgaaa
     2641 cattagctgt ccatatttgg aagatcaata cagaaggcac gatgcctgat ggtgtttctg
     2701 tttcggctgg cgcttctgcc gtgttgatca ttgctgtttt actgttcaac ttcggcgctc
     2761 gtgcgattgg caaacgatta taccgaaaaa tgacttcagc ctaaggagaa gaagcaaaat
     2821 gaaaaaatat aactggaatg aaacaaatgt catcaccatg ccaaaagaga aagaagtagc
     2881 actatatacg gatgatctac atgtctggta tggcgacaat gaagcaatca aaggagtgga
     2941 tctggaattt gaaaaaaata agatcactgc actgattggt ccttccggct gcggaaaatc
     3001 tacgtatctt cgttcgttga atcgaatgaa tgatgggatc gctaatacga aaatcactgg
     3061 gaaaatcatg tatcaaggcg tagatattaa tgcgcctcaa gtggatgttt atgagatgcg
     3121 caaacggatt ggcatggttt ttcaacgtcc taatccgttc agcaagtcga tttatgacaa
     3181 tattacattt gctttgaaac agcacggcga aaaaaacaaa aagaaattag atgaaatcgt
     3241 tgaaacaagc ttgaaacaag ctgccttgtg ggaccaagta aaagacagct tggacaaaag
     3301 tgccttggct ttatctggcg ggcaacagca acgtttatgt attgctcgtg cgatcgcgat
     3361 gaaacctgat atcttgctgc tagacgagcc ggcaagtgct ttggacccta tttcgacagg
     3421 aacggttgaa gaaacacttg taaacttgaa agaagactat acgatcatca tcgtgacgca
     3481 taacatgcaa caagcagctc gtatcagcga ctatactgcc tttttctatc taggaaaagt
     3541 aatggaatat gacaaaacta acaagatatt taccagacca aaaattcagg caaccgaaga
     3601 ttatgtgtcc ggtcattttg gttaagacgg aggcctcaac atgacaaaag aaattatttc
     3661 atctaaagat cttcatctgt attatggaaa gaaagaagca ctaaaaggga tcaatctaag
     3721 tttcaatcaa ggggaaatca ctgcgatgat cggtccttct ggttgcggga aatccactta
     3781 tctgcgttct ttgaaccgga tgaatgacct gattccgaat gtaacgatca ccggaagtgt
     3841 tttatataaa gacaaagaca tctatggtcc aaaaacagat gttgttgaac taagaaaaga
     3901 aatcggcatg gtattccagc agccaaaccc atttcctttt tctatctatg aaaatgtcat
     3961 ctatggattg aaattaaaag gggaaaaaga taaaaaagtc cttgatcaag tagttgaaga
     4021 aagcctgaag gcagcgtctg tttgggatga tgtgaaagac aaattgcata aaagtgcttt
     4081 atctttatcc ggtgggcagc agcagcgtgt atgtatcgca cgtgttttgg cagttaatcc
     4141 ggaaatcatc ttattggatg aaccaacaag tgcgcttgat cctgtttcta ctgggaaaat
     4201 cgaaagtatg ctgttagaat taagagagcg gtatacgatg atcatcgtga cccataatat
     4261 gtctcaagct tcacgtattt cagataagac ggcattcttt ttagatggtc acttgatcga
     4321 atacaacgat acgaagaaga tattcatgaa tccagaaaaa caagagacag aagattatat
     4381 ttcaggtcga tttggataag gaggaaacgg aatgctacgt acacaatttg aagaagaatt
     4441 gctgaatctc cataatcagt tctacgaaat ggggatgatg gtgagcagcg ccgtgcacaa
     4501 gtcagttcgt gcatacatca aacacgataa aatcttagcc caagaagtta tcgaaaacga
     4561 tataaatatc aataacatgg aaacacgctt ggagaagaaa agttttgaaa tgatcgcatt
     4621 gcaacagcca gttacaactg atttgcgtat gatcattacg gtcatgaaag ctagctcgga
     4681 tttagaacgt atggccgatc atgcggtgtc tgttgctaaa tccacgattc gcgtaaaagg
     4741 gcagacgaga ataccggaaa tcgaaaaaga gatctccgat atgtccgatt atgtgaaaaa
     4801 aatggtggac aacgtcctag ttgcttatgt caaaacagac gaaaaagacg cacgtacgat
     4861 cgccaatatg gatcaaagag tcaatgacta tttcaatcga atctataatg caacaatcaa
     4921 aaatatgcag gaaaatcctg agacagtcat cagtggaaca gactacttga atgttgccag
     4981 ttatctagaa cggatcggag actatgtgac aaacatctgt gaatggatcg tctacttggc
     5041 tacagggaaa atcactgagt taaatacgaa ccacaatgag attttctaaa ctgaagctgt
     5101 gattatgccg tttgtttagg aaaagaggtt gtgaaatcag cggttgtgaa aaagctgttc
     5161 tgcatcaagt aataagaaca gtcaaacaaa aaatagctcc tcatattttt cgtttggctg
     5221 gacttattac cgcagatgca agcttttgaa caccgtttat tcgggaaagg gtttgtgaca
     5281 aaacatgtca caaacccttt tcatcatttc atagaaagga taaagaatgc aaaaaaaaat
     5341 tagcatcatc actatatttt ttatttgtgt gcttacttca tgggttattc agcatcaagc
     5401 tgctttatat gaagtacctg tcatcgagat cgaaaaagta cgaataaaag aggatcatca
     5461 attgattaca ggaagactga tgaacacgga tcaaaaagga gaatcgattt atttatcggt
     5521 tccttatcaa aaaaatcaaa tagaaacagc aaatataaaa gcgagacaaa tgtatctagt
     5581 ccaaatgcat ggagatgaat ggcagctagt agcaaaaaaa aaatgatggc tggcttttct
     5641 tcttcacaag tatctccatt ggcgccatgt tgcttattgg cggaaaacag ggtctatttg
     5701 ctttaggaag tctcatcatc aatatcgttt tacttttact tttgttgctc atctttacta
     5761 aaacagaagg gatttctcta ttaaatatat ctatcctgtt cgtcgttata gggatgatta
     5821 ttagcatatt ggctttagat ggatggaata gaagcagtat aatcaaaatt tcagctgcag
     5881 ttacgagtgt ttttttagca ttttttattt gtcttttgac aatgaatcat tggaaagacc
     5941 aaggactgcg ctatgaggaa ctgaattatc tgacacgacc gtatcgttct gtttttcttt
     6001 ctagcgtact gattggaaca gctggaggaa cactcgatac cgttatcaca gtcattgcga
     6061 cattagaaga attgactaag cgacaaccag aaataacagc gaaacagtta tggctttcag
     6121 gaaggcaagt gggtcgagat gtgattggct cgatgaccaa tatccttttg ttcgtctata
     6181 tcagtgggtc agttccatcg cttcttttat atttaggaaa tcaatggtcg ttcaaagaaa
     6241 cgatagaaca gcatttatca ttggaatttt tacgcgtcat tgctggcagc ttaggaatag
     6301 tattatcgat ccctatctcg gtcctctttt ttctgactgt aaggaggctg aaacgatgaa
     6361 tgtacttatt atacttgttg ggattttagc aatcagcgtg ctacttattg gcggtacgca
     6421 aggtatgtat attcttttag gcttattcat caatttaggg atctttttcc tgttgttatt
     6481 cggttatcat cagaagtggc cgatactggc attgtcggtc ataggatttt tattgattgc
     6541 tgtggttatc ttatttttta tcaacggtta taatctaaaa atgcgtgcag cttttgtgag
     6601 tatactgatc tttttatttt gtttcctact attgcttcct atcactgatt ttttagcgat
     6661 ccaaggtttt acatcggtag aactagaaga attatctggc ttagataaga ctttagcgat
     6721 tgattttaga ttacttacga gatcgttgct tctgattagt cttagtggtg ctgttttaga
     6781 tgctagtgta gcaatttcta gtgggacatt cgaagtatat caggcaaatc cgcaattatc
     6841 tttttaccaa ttgcgccatt ctagtttcgc tattgctaaa aaaatattgg cgtcaacagt
     6901 aatgacactt ctttttgcat tcatgggaag ttctttagcg ttgatcctct ggtttattga
     6961 tttagacatt ccttttcagc aagtgatcaa tgaaaaatca tttgttctag aatatacgat
     7021 ggctattctt accacattgt ctgcactact tgttcttcct ttaacctgcg tgactacagc
     7081 atatctcttt acaaaaaaga aagaacaact caagatggag taaaagttac aacttaagtc
     7141 ctatgacatt tttactgaat cagtgcataa tatggatgta aggaaaagct tgcaaacaat
     7201 tttgcttaag gaggcaattt ccatgaaaga aagagaacgt attttagatt tagtgaaaaa
     7261 aggaatcctt tcgactgaag aaggcttaga tttattagaa agcatggcaa ctgaaaaaga
     7321 cgaaaagcaa ataaaaaaag aagcagacaa ggtaactgct agtcataaag aaaaagatca
     7381 ggcaagtcaa ttgatcgata aacttgaaaa cggcgaagaa gaaatttctg agccagttga
     7441 tccaaaggaa agagaaaggc aagatcaaga aaacttagaa aagatcttag atgaactagc
     7501 aactgaagcg aataaaactt cggcgcgtct agatgaagta aatgctcaat tcgctgacaa
     7561 taaggcagca cgcaatgaga aacaggaagc attgatgcag ctgaatacaa aagaagaatt
     7621 aggcgagttg acagaagaag aattagcaca gcgtcagacg ttagaagcag aaatcaaaga
     7681 attagaagct agtggcgata cactgttaga agaacaattg aaattagaag cagaattaaa
     7741 agatatccgt aagaatcaat ggtctgagaa aaaagaaacg tttactgata agtttgaatt
     7801 gccagatgat tggaaagatc aagcaacaga tacactgaat caagtaggcg aaaaaatgtc
     7861 agaagctgga tcacagttag gcaaattctt gaagaaaaca ttccaaactg tttcagaaac
     7921 agtgaatgac aacatggaat ggaaagatgt cagcttacgt gtccctggga ttgcgacaac
     7981 gaaatttgag catgaatttt actatgaagc tcctgcagca agtatccttg atatcaaggc
     8041 agcaaacgga aacgtgacgt taaaaacgtg ggacagcaac gatgtgaaag ttgaagctaa
     8101 gatcaaactt tacggaaaaa tgggtgctga accatttgaa gcattctctg aacggagcca
     8161 gattgaggtt aatgaagatc atatctcctt ccaaattcca aataaacgtg tgcgtgcaga
     8221 ccttgttttc tacttaccta aacgagtata cgaccacgca gctattaaac ttctaaatgg
     8281 caacatcatg attgaaacat tggaagctaa agatatttat acaaaatcta cgaatggtaa
     8341 catcatcgtg gaccaattaa ctgcaacgat gctggaagta gaaggtgtaa acggcaatat
     8401 cgatattcga aacgggaaca tcttagattc tattatcgaa acagtaaatg gtacagtgac
     8461 atttggtgcg acagcagaaa acctttctgt gtctttggta aatggtgatg tacgtcttac
     8521 gattaaagaa gataatttga aaaaagtaga agcaagttca gtgaacggaa atgtcaaagt
     8581 cgctttacca gatggcatcg gtttggaagg acatgctaaa acaagtcttg gaagtatcaa
     8641 cagccgtctg tccaattacg aagtagttcg tgagaaaaaa gaacggacaa accaaatgtt
     8701 gcaattccgt cgtgtttcag atggtgaaat cacgcaagtg caactttcaa cgacaacagg
     8761 aagtatctat ttaaaagata cagataaata aagaggttgt gaaagagatg ttcagccttg
     8821 agcaataaga agcgattttg taaaatagct tcccctattt tacaaaattg tgccttattg
     8881 ccgataggct atctcttgaa caccgtttac caagagatta tgaacctgcc aattatcgcc
     8941 gagtcacaag gaataatttc agaaaaagct cgtcacgttt tatgaatatg gtaatttgtg
     9001 accgagaatt ttgcagaaag acaccgatta agaagaaggt tgtcacaacg attttcttca
     9061 tttaaaatag tagaacagag gtgagacatg atgaaaaaaa agttgacaaa atccaataaa
     9121 aatgttgttt tgacagggac tttagcagga ataggagaat acatcgggat tgatccgact
     9181 gttatccgtg tgctttatgt attcctgagc ttagttgctt ttggaagtcc aatcatttta
     9241 tacattttat tagctttgat tatcccatct gcgcgttctg cacgaacaaa ctatggacat
     9301 aacaatgcat attatgaaaa aaacaattat cgtgaacaaa ctcgtgaaca aacaaaaaaa
     9361 cgcaaagaag cggaaaaaat cgatgatgac gaatggagtg acttttaatg tcgtactttc
     9421 aacgtatttt agttaatacg ttaacattca tatcattggc tgttcttttt cctgcgatgg
     9481 tccatgtgag cagtatttgg acggccgttc ttgccagctt cgtattgtct gtgttgaata
     9541 tgtttgtcaa accgattttg acgatactgt ccctgccctt tacattagtc acattgggat
     9601 tgtttacgtt tgttatcaat gcagcgattc ttaaaatgac ctcctttttt gtgggagcag
     9661 aacattttag tttttcttca ttcggtgcag cgttgttagt agctatcttg atgtcgcttg
     9721 tcaatgtaat tgtcagtgaa cataacagta gaaaataaaa gaaagctgtg ccgaactatc
     9781 ggcgcagttt ttttatttag aatcaggaat gcgttttcta ttacattggt aattaaataa
     9841 aaacgttttt tttaattggt agtacttttg gctagacaat gataaaatga tagagaacac
     9901 tctaatagaa atgaggtagc atgaatgtca gaagttgtaa aagttagcca attagtgaaa
     9961 aaattatctt tggaaatcgt gacaggcgac gagaaaagct tagaccgtgt catcgtaact
    10021 ggggacatct cacgcccagg actagagttg actggttatt ttaattatta ttcccataat
    10081 cgtttacagc tatttggcag taaagaaatc agttttgcgg aacggatgat cccagaagag
    10141 cgtttgatca tcatgagaag attatgtagt gaagatatgc ccgcatttat tatttcaaga
    10201 ggattaccgg ctccagaaga aatgatccag gcagcaaatg aaaatgggat agctgtactg
    10261 cgttctccca tctcaacttc tcgtttatta ggagaattat ccagttattt agatggtcgc
    10321 cttgcccctc gaacaagtgt ccacggtgtt ttagtggatg tttacggatt aggtgtactg
    10381 attcaaggtg acagtgggat aggaaaaagt gaaacagcgt tggagttgat caaacgcggt
    10441 catcgattga tcgcagacga tcgagtagat gtttatcagc aagatgaatt aacggtgatc
    10501 ggagaaccgc ctaaaatcct ggaacatcta attgaaatcc gaggaatcgg gatcattgat
    10561 gtaatgaatc tttttggtgc gagtgcggta cgtggctcta tgcaagtcca gttggctgtt
    10621 tatctggaag catgggcaaa agataagaaa tacgaccgtc tgggctctga agacacgacc
    10681 gttgaaatcg cggaagtggg cattccacaa ataaaaatcc ctgtcaaaac aggacgaaac
    10741 gttgcaatca tcattgaagt agccgcgatg aatttccgtg cacgtacaat gggctttgac
    10801 gcaacgaaaa catttgaaga aagattaagt cgcttgattg aagaaaactc aggcaacgac
    10861 tagcaaggag tgacaatatg ttagcacaaa tcaatcgagt tgcttttgag cttgtaggga
    10921 ttcctatcta ctggtatgca ttgatcatcg tatcaggtat cattatcgcc atgtggctta
    10981 gcagcagaga ggctgttcgg gtaggattaa aagcagatga tgtgacagat tttatgttgt
    11041 ggggattgcc tatctccatt attggtgctc gcttatatta tgttttattt gatcttcccc
    11101 agtatatagc tgatccaatc caaatattca atatccgttc aggaggctta gctatttatg
    11161 gcggactgat tgcaggcgcg atcacgctgt atttttttac taaatatcat tttatttctt
    11221 tgtggacttt tttagatatc gctgcaccaa gtgtattatt agcacaggca atcggtcgtt
    11281 ggggaaattt catgaaccac gaagcatatg gaccagacac gacgcgaagc ttcttagaaa
    11341 gtctgcattt accgcaattc atcattgata atatgtatat cgaagggatc tatcgtcaac
    11401 caacatttct ttatgaatca ctttggagtt tgattggatt tattttgctt ttgtttttac
    11461 gaaagaaacc acaccttttg aaaaaaggcg aagtcctttt atgttatcta atgtggtata
    11521 gtttcgggcg tttctttatt gaaggattac gtacagacag tctttacttt ttaggtgtga
    11581 tccgtatttc tcaattatta tctgctgtgt tatttgtcgg tacattgatt ctatttattt
    11641 ggcgcagaaa aaaaggaaat ttaccggatt atgaccgctc attaggaaaa aatcaacaaa
    11701 ttatctgatt tttagagcgt taaaaatgaa aaaaatttca ggagtggtaa aatgaattat
    11761 agagtagcgg ttttaggacc aggctcttgg ggtactgctt tggcacaagt cctcgccgaa
    11821 aacggacatg acgttcggat ttggggacat cgtgcttcac aagtagaaga aatcaacacc
    11881 caacacacga atcaacgtta tttaccagat cattatctac ccgattccat ccaagcattc
    11941 accaatatgg aagatgcagt aaaagacgca gatgcggtgc tattcgtcat tccaacgaaa
    12001 gcaatacgtt ctgttgcaaa agaactagtg cctaaattga atacaaagcc agtgatcatc
    12061 catgcaagta aaggattaga acagggaaca cataaaagga tctctgacat cttgttagag
    12121 gaaatcccag cagaaaaaag aaaagctgtt gttgttcttt ctggaccaag ccatgcagaa
    12181 gaagtagcga aacatgacat cactacgatc acagctgcaa gtacagatgc aaaagcagca
    12241 aaatatgtac aagagctgtt catgaataat tattttcgga tctataccaa tcctgatgtg
    12301 atcggtgtag agatgggggc agctttgaaa aatattattg ctattggtgc tggcgctatt
    12361 cacggcttag ggtttggcga taatgcaaag gcagcaatca tgacgcgcgg attagctgag
    12421 atcagccgtt taggtgtagc aatgggtgcc aacccgctga cctttatcgg attaagcgga
    12481 gtaggcgatc tagtcgttac ttgcacaagt gttcattcta ggaactggcg cgcaggcaac
    12541 ttgttaggac aagggcagcc cctagaagag gtgctagcca atatgggaat ggtcgttgaa
    12601 ggtgtgaata ctactcaagc agcgatggaa ctagcccaaa taatggaaat cgaaatgccc
    12661 atcactcaaa caatctatga agtgctgtat gaacaaaaag aaatcaaaac agccgcaaaa
    12721 gaaatcatgt tacgtgatgg gaaaaaagaa aatgaattct cattaacaat tttttgaagg
    12781 agcgaatgta tatgaaagtc aaaaaagcag ttattccagc ggcaggatta ggaacaagat
    12841 ttttaccagc aacaaaagct atggcaaagg aaatgttgcc aattgttgat aaaccaacaa
    12901 tccagttcat cgttgaagaa gcgttgaaat caggaatcga agacatcttg atcgttacag
    12961 gaaaagctaa acgaccaatc gaagatcact ttgattcaaa tattgaatta gaaacaaacc
    13021 taagtgaaaa aggaaagacc gaattattga aattagtaga agaaacgaca gatgtcaact
    13081 tgcatttcat ccgtcaatct catccaaagg gtttaggaca tgccgttctt caagcaagag
    13141 cctttattgg aaatgaaccg tttgtcgtta tgctaggcga tgatatcatg gaagatgaag
    13201 taccattgac acagcaatta atcgatgatt acgaacgtac tcatgcttct acgatcgccg
    13261 ttatgcaagt tcctcatgat gaaacttcaa aatacggaat tatcaatcca ggagaagtat
    13321 tggaagatgg gttatacaat gtcaaaaact ttgttgaaaa accagatcca agcaaagcac
    13381 caagtgattt agctattatt ggacgttact tattgactcc agaaattttt gatgtattgt
    13441 ccgagcaaca accaggagcc ggaaatgaaa tccaactaac tgacgcaatc gatacattga
    13501 ataaaacaca acgcgtattt gcccgtaaat tcacaggtaa acgttacgat gtcggtgaca
    13561 aatttggttt tatgaaaaca agtattgaat atggtctaac acatccagaa gtaggtgcac
    13621 ctttacgtga gtatatcctg tctttaggta aaaaattaga agcagaagga agcaagatcg
    13681 atcataatcc aaaaggaata acagaaatca aagaagaaaa gaaaaaataa cccttttttc
    13741 taacgagctt cagctgctaa ttgaataaaa agtagttgaa gctcgttttt atttgtttaa
    13801 aaaacacgaa aatgctatcc ttatagaaaa gagagacaag aagggagttt gatcatgtca
    13861 ggaggagaaa ttgcaggatt gatcgcagca atcgcctttg cgatacttgt cgtttttatc
    13921 gttcgtgtgt tgttgcaagt ttctaaaact ttagaaaaag tagatcagac tgtagcagaa
    13981 gcaaatacga cgatcgaaat cgtcacaaaa gacgtagatc ttttgtctag acaagtagaa
    14041 ggcttgctgg tcaaaagtaa tgaactgctc ttggatatca atggaaaagt cgcaacgatc
    14101 gatccattgt tcacagcagt tgctgattta agtgaaagtg tatcagaact taatcattct
    14161 agtaaaaaca tcgcgacgaa agtcggcgga atcggtaaaa cgacagctaa agcgacggtt
    14221 gccggaaaag tcggtgggac agcgatgaaa ttttttaaaa acaaaaaaca tactgaaacg
    14281 acaggaggaa aataaaaatg gctaaaaaag gtggattttt attaggtgca gtagtcggag
    14341 gaacagccgc agcaatcgcc gcgttattgt tagcaccaaa atctggtaaa gaacttcggg
    14401 atgaattagc tgcccaagcg gatgatttga tggatatggc ttcagattac acagatatgg
    14461 cgaaagaaaa atcgactgag ttaacaggta ttgcaaaaga aaaagcgcaa gatctttctc
    14521 aacaagcagg tgatctagca ggtagtgtca aacaaaaagt aagtgaatca gcagatgaag
    14581 caggaagtga atctgacgat atcttgttaa atcttaaaga acaatcagct gacttatcta
    14641 atcgtttcaa aaaaacggca gaagatatga aaaaacctgc agatgaatta ggaagtattg
    14701 ctaaagatac ttcagaagat atcatgattg atgtaaaaga cgctgctggt aaagcaggag
    14761 atactgtcaa tgaaggaatg tcagaagcaa aaccagttgc agatgacaca aaagaaatga
    14821 tgaaaatggc aaaagaagat gcgaaagaag ctaaaaaaga aataaaagat acaatgacag
    14881 attcatctac aaatcactaa aatcactaaa atcacaaatt tatagaataa aaaggtggga
    14941 gcggactagc tctcaccttt tttactctta tttttctaaa actagtaatt cttttggtgt
    15001 agtcgtgaat ggcacacagc catcgcttgt cacatataca cagtcttcga tacgtacccc
    15061 tactttttca ggaatataga ttcctggttc aagagagaag cacatccctt cttcgattac
    15121 taagtcattt ccttctacaa gggaagggaa ttcgtggacg gttgttccga tcccgtgacc
    15181 taaacggtga ttgaaatatt cgccgtagcc atagctgttg atcacgtttc gtgcgatttg
    15241 atcaagttca cctgctgtca cacctggacg gacggcttct tgtgcggcaa gctgtgcttc
    15301 aagagtgatg ttgtatattt tttcttggaa gtcggttggt ttttgataag caattgtacg
    15361 agtagcatca ctgcaatagc cattccaaac aacgccaaga tcgaataaca caagttcatt
    15421 cggtgaaatc ttcgtgtttc ctggtgtacc atgagggctt gcagcatttg ctcctgcaag
    15481 gactaatgtg tcgaaagaca tttgtgaaac accttgtttt ttcaattggt attcgatttc
    15541 tgcaatgatc gcttgttcag tcacgccttc tttcactgct ttaaagccaa tctcaaatgc
    15601 aacatcggcc catttaccag cttcgatcag tttgtctttt tcctctagag ttttgatcag
    15661 ttgtagacgt tggatgatgg aagctagatc agtgtaagaa tccgttcccg tcaagatatc
    15721 agagatagca tcgaagcgct cgacagtcaa ggcgttcttt tcaatcccta cattgccagg
    15781 ctgaccatag cgagcacgaa gttcttttcc gatgatctcc caagggtttt cgctgtctaa
    15841 atagccacgg acatcatacg cccaactact gttttgagca tcttcaactt ccaaagcagg
    15901 agtgaaaagg aaaggatctt gttcaagagg gataaaaaga gctagtacac gctcatgagg
    15961 atcactttcg tatccggaaa agtaagcgat gtggccaggg tcgctgatat aagccaattc
    16021 gacttggtgt tgtgccatcc attgacgtag ttcattgatt tttacgttat tcatttggca
    16081 acctactttc taaattaatt ttgtattcaa taattgtacc actgatttat taaaagacca
    16141 acgttctaaa aactgaaaaa agtaaaaatt ttcatgaaaa cagagataaa acggttgcaa
    16201 ttcttgagat tatttgatat tctattttag aaatgtaaga cgtattttca gaaaacatat
    16261 aaaatatgaa taggagaaca caaatggaaa agcaaacaat cactatctat gatgtagcga
    16321 gagaggcaaa tgtttcgatg gctactgttt cacgtgtcgt aaatggcaat ccaaacgtca
    16381 aaccagcaac aagaaaaaaa gtcttggaag ttatcgatcg cttggattat cgtccaaacg
    16441 cagttgcgcg tggcttggca agtaagaaaa caacaacagt tggggtaatc atccctgatg
    16501 tcagcaatat gttctttgct tctttagcac gtggtatcga tgatgtggca acaatgtaca
    16561 aatacaatat tatcttagca aattcagatg gtaacgacca aaaagaagtc aatgtattga
    16621 ataacttact ggctaagcaa gtggacggcg tgatcttcat gggtcaccat atcacagacg
    16681 aaatccgtgg agaattttca cgttcaaaaa ctcctgttgt attagctggc tctattgatc
    16741 cagatgaaca agtaggtagc gtaaacattg attatgtatc agcaacaaaa gatgcagtaa
    16801 acaaattggc aaaaagcggc aataaaaaaa tcgcttttgt cagtggtgcg ttgatcgatc
    16861 ctatcaatgg acaaaatcgt ctgaaaggct ataaagaagc attaagcgaa aataacctac
    16921 catatagcga aggattgatc tttgaagcac aatacaactt caaagatggt ctatctctag
    16981 tcgatcggat ccataatagc ggtgcaacag ctgtctatgt ttcagatgat gaattagcca
    17041 tcggtatttt ggatggttta ttagaccgtg gcgtgaaagt accggaagaa ttcgaaatca
    17101 tcacaagtaa caattcacta ctgacagaag tagctcgtcc tcgtttaaca agtatcacac
    17161 aaccattata cgatttaggg gcggtatcta tgcgcctatt gacgaaaatg atgaataaag
    17221 aagaagtcga agaaaaaacg attatcttgc cttatggaat cgaagaaaaa ggatctacaa
    17281 aataataaaa ggacaaccat tcagaggttg tgagcctgcc gtttaactct gcgttacaag
    17341 gagcaatttc aaaaaacagc atttcatgtt tgatgaatat tgtgactcgt gattcggagt
    17401 tggcaggaga acaccgttta ttcgggaaaa ggggttatga caaaattttg tttaatcctt
    17461 tttttttgtc ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta tataaaacaa
    17521 tccgtgtata gatgctgcat tatgttcacc accatcaaaa aaataaggga ctgtgtattc
    17581 tattaaatca atcatctttc tcatctgatt ctttggttgc ttgattcgct cttgcataag
    17641 ctgaagcggt gttccagtaa tctgtatagt tttcatcggt accgccaacg ccaaatttaa
    17701 aggcgctttt cttcggtcca tttttcgccc atagcgattc aactgttttt cctggtgttt
    17761 ggatggattt tttattgaca gtaacttttc caggtgtttg accagtaaat ccagatactt
    17821 ttttcttcat cacatcagat gataattcga atttctcatc agtgccaaaa atgtcaggtt
    17881 ttgcttggta agcttgattg atcagattgg caagataatt agccgaacgt atccttgctt
    17941 tgctgtccat tccagtattg tcatcgtgcc ctgcccagct actgatggta atagacggag
    18001 tagagacaat tagccatgaa tctcggtatt cattggtaga accagttttt ccgacccaat
    18061 ctgcttttcc tagatttccg tttaagcttg agatggcatc tttgaatggt gtagtgattt
    18121 ttgcattgat cacactgcgc atcatgtcat tcatgatcga tgccgttgct tccgaataga
    18181 tccggacaga gttgctttcg tgtttataaa ttacatttcc tgcgttatct gtgatggaat
    18241 cgatgatata gccttcttca tagacgccgc cgtttgctaa agcctgaaat ccattggtct
    18301 gttgaagcgt cgtgacatct actgtaccta aaggagcaga ttcaacgccc caattgtcat
    18361 ttgccgggta gttcatcttt gccaagtagt gctcgtaagc atattgtttc gatccaccgg
    18421 aattcaacac atcttgatat aagtgataag ccgggatatt gttggaccat tctagtgact
    18481 cacggacggt ttggaaggtg ttcgatcctt cgttagtagc attgacgatt ttctcgccag
    18541 cattttctcc ttcttgccaa gttgttgcat aatctgatac acgggattct gatccgataa
    18601 gccccatgtc gattgcaggt ccataaacaa gaactggttt gattgatgag ccagcttgac
    18661 gttctgtatc gaaggcatgg ttattttgat tctgactgta attccgtccg ccaacgaatc
    18721 cgtagatgcg gccagttctg ttatccatca atacatttcc ggtttctact tgactgccag
    18781 caccatcatc taacatgtat ccataatttt ctacgccatt ttgcaatgca gcatagacat
    18841 ctttatcgat tgtcgaatgg attgtatatc ctttattttg gatcgtttgc tgtgcctttt
    18901 gataataagc gtcactgacc gatgaatcag acatatcagc gttgtctttt tcagccaatt
    18961 gttgtgcaat gattcttgtt gcttcattca tcacagtata atacaagaat tctctgtcag
    19021 tctgttctgc gatttgttgt ggtagaaagt cttttgtaag gtcataggct tttgcttctt
    19081 cgtattgttc tttcgtaatt tggccttcac gatacatact gaataaaaca aaatcttttc
    19141 tggcaaggcc ggcagaaaga tcttctttta gcgcacctgt gttcgtgtat ggactatacg
    19201 tgatcgggct ttggggtaat ccagcgatat aagcagcttg cggcagcgtc acatcttttg
    19261 catctacacc aaagattcct cttgcagctt cctggactcc agcaatgttt tgtcccttat
    19321 tattacgacc aaatggtgag acattcaaat acgtagcaat gatctcatct tttgaaaagt
    19381 atttttctac ttgtgcagaa agaatgatct cgtttgcttt acgtttgaat gttgtttcat
    19441 ctgtaaggat ctgctgtttg actaattgct gtgtcaaagt tgatccacca gaagagccaa
    19501 taccagtagc ttcagatact aatgctcgta aaacagcttt aggaacgtaa ccttggtgtt
    19561 tatcgaagta ttcatcctct gtgctgataa ttgcagtttt caataaaggt gaaattttat
    19621 cagatgaaat agtcgtgcgc atcagatctg tctggatttt tgatatctct gtattatctg
    19681 cataaacaat ctttgacgtt tctgtaatgt ttcctagttc tgtctgcagt gcttttttag
    19741 tcggcaattg tgtgtcttcg acgagatagg caaaatagcc agcgcctatt ccaataccta
    19801 gagctgcgaa catcaaaaga agaacagtaa taaaaacagt caatgattga aaaactctaa
    19861 aaataatctt aggaacaaac catttttctt tttttcttct attctgtttt tttcgagtat
    19921 ttttgcgtgg caaaagggtc acctcaacta atggttttat ttcgctaatt atagcaaata
    19981 atagaacaaa aaaacagaca aggctgtttt tggcaggaat ttctttttta aaagagttaa
    20041 aacgtgagaa aatgatcttt tttataaaag agttcttaag cttttcttta gagaaaattt
    20101 cagttactat ggagaacagg gcaaagaaaa atcaatcatt ttctttgtat atcatcttac
    20161 caatatatag gaattgttag taacaattgc ctttcaagga ggaatccatc catgttatta
    20221 ggctcacacg tcagcatgag cggaaagaaa atgctgttag gagcagcaga agaagcagcc
    20281 agttatggat cttcgacttt tatgatctat acaggcgccc ctcaaaacac tagaagaaaa
    20341 gccatcgaag agatgaatat tgatgccgga aaagcgtaca tggcagaaaa cggtctaaca
    20401 aatatcgtcg ttcatgcccc ttatatcatt aatttgggga atacgatcaa accagaaatg
    20461 tttccttttg ccgtccaatt tctgagagaa gagattgttc gtgcggaagc tttaggcgct
    20521 actcaaatta cacttcaccc aggtgctcat gtaggggcag gaacagaagc cggaattgct
    20581 agaattattg aaggcttgaa tgaagttttg acaaaagaac agacggcaca aatcgctttg
    20641 gagacaatgg caggtaaagg tacggaaatc ggtcgaacat ttgaggaatt agcgcaaatc
    20701 atcgatggag taaaattgaa tgaaaaatta tccgttactt ttgacacctg tcatacgaat
    20761 gatgccggtt ataatattaa agaagacttt tcaggtgtaa tggaagagtt tgataagatc
    20821 atcgggttag atcggcttaa agtactccat atcaatgatt ctaaaaatcc gcaaggttcg
    20881 cataaagacc ggcacgccaa tattggtttt ggaacaatcg gattcgacac gctgaataag
    20941 atcgtccatg atccaatgtt tgacaatatt tcgaaaatct tggaaactcc ctatgtcggc
    21001 aaagataaaa agaaagctta cgcaccatat ggaaaagaaa tcgccatgtt caaagcacaa
    21061 atattcgatc cagaagtgtt tcctgagtta ttagcagaag aagtgatact ctaagatttt
    21121 ctatctgaca gcagcaaaaa aggaccaggc acattgcctt gtcctttttt gtttaagaaa
    21181 caaaggagtg ctttttgcag tctttttcat catgcatctt ctcccccctc tttttaaatt
    21241 tagacaaaca gggtatactg gtagaaaagt aaaaaaacga aaagtttcac aagcaagtgg
    21301 caaaacgtga ttggaaggac gaaaagatgc tgaacacttt aaaacccttg atcaaccaac
    21361 taaaaaagaa acatacatac tttattcttg gcatagccct attatttaca attattcgtt
    21421 tgtatttata tagtaaagca atctatggaa cagacatgtc ggcaacctat gatgaccagc
    21481 tgctgattcg ctatgctcaa aatattttgg acggtaaatg gctaggggag tatacgacta
    21541 caacactttc caaaggaatc tcctacagct tatttttagt acttgcacat aaactgcatc
    21601 tttcttatgc agttttgttc ggcatgttca gtatttttgc cagtatattg gttgcactcg
    21661 cgtttaaacc gatcgtgaag aacaagtatc ttcttttaag tttctatttt tattttttgt
    21721 tttctccgat tagttttaca catgaatatt ccactcgaac gtatcgtaat gccctcgtga
    21781 ttccggctgt tgagatcatt atcgcttgtt tactagctat ttattaccgt aaatatagtt
    21841 ccagcaaaaa aatgctgccg tggtttttag ggctagctgt ttcttttcct ttcttttggt
    21901 tcattcgcga agattccatc tggcttcttc cttttactgt agtcgcgtta ggcatcagtt
    21961 tcgtccagat cttgctagga caagactttt ctttcaaaga agcaaagaag ttaaaagaac
    22021 gaccatttct cctttcgaaa caagaatggc tgaaactttc attgttttta ctccctctag
    22081 tcggtttctc catcgtctat cagtggatcg aatataaaaa cgagacaaca tatagtattg
    22141 ccgccatcaa tgaccgttcg agtggcgaat ttggacgttt gatgaaacag ctgatccgaa
    22201 tagatgacga aacgaactta aataaagaaa acagtgagat atgggtctcg catgctgcat
    22261 taaataaagc attagacgca tctcctacat ttcatgctgt ttctactcgt attgacgaat
    22321 tgtatacgac tcatgcgtgg acccaaggtg gaaaagtaaa agaattacca ggagatatca
    22381 ttttttgggc attgcgagat gtggtaagcg aatctggtta ttaccaaaac aatgcaaaag
    22441 aaaccaatga tttttggaaa aaagtcaatc aagaattaga agaagcctat caaaagggaa
    22501 ctatcaaaaa gaaaaaagaa ttctatctga tgggatcagg ggatggaaag acgatgaatg
    22561 atctgccaat cgtatttgct tttctgaaat caggatatgc ctatgcatgg cgatacaaag
    22621 atttccatca aggggggaat tatagtttcg gtacgcaaga acaagtcgaa caggcccaag
    22681 aattattgaa tcttccacta atggataatt ggatcgatag cagtgatccg agaacacctg
    22741 atttccagtt gacaaaaaca gcaaaagtcg cgaatgtcat gataaaaatt taccaagttc
    22801 tggccattcc cgtgctgatt gcttcaatag cagggatatt acttatgata ctaggaaccg
    22861 catttgcaaa agctgatcgt gcctattata gttcctcttt gattgtagtc accggattaa
    22921 tactgacaca attggttttt cttttcggcg tctcgtggtt ttgttcttat gcgccagaaa
    22981 aaaaggatta ttttttaagt gtctacactg gcgcaggcgt gccattaacg caattcatcg
    23041 tagtaacaag catgctagtt ttcagtaaat tgaatctgaa aaaagcttta tcttccaaat
    23101 aaaaacatac taagattaga ggagaacatc attgacgaat gatgttctcc tctattttct
    23161 atttttagat tatagtgaag agtgaaagaa agttcgaaca aagccttgag gactatgagt
    23221 ccctatcaaa aaccgaactt ctttactgtc attttagaat caggtttacg tatgttgggg
    23281 ccatgagccc gtgtatagga aattggaatc gaaatgaagc agtaaagttc tttcaaaact
    23341 taaaaaggag gaaaacaaat gccttacatt cttgcattag atgtttcaat gggacacagc
    23401 tacagtgtcc tatacaaaga cgacacctgc ttatttgaag acgagatcga acacactcaa
    23461 agaggatttc atgcattact cgaagagatc cagcacttgc ctgaacgtcc attgattgtt
    23521 tttgaagcaa cggggattta ttccagacca gtcgaaaagt tctttcaaga tcatcacttt
    23581 tcttactgtt tgttaaaccc gttagaagcg aaaaaacaga tggaagaaaa caccttatgc
    23641 agttggaaaa cagataaatc ggatgcccat cggctcgcac agactcatct taaaaatcaa
    23701 cgtcagccaa aagaagtaca aagcaatttt tacttagaga tgcgcgattt agcccgtttt
    23761 tatcaagaaa ttgagaagaa aatcactcgt ctgcgcatgg atttacacaa ctgccttcag
    23821 ttgacttttc cagagcttga acagttcttt ttaaacaggc tgacccctta cgcattgata
    23881 ttgatccgtc tttttcccca tccagatttt gtattggcat ctactcggac aaaaataaaa
    23941 aataaactga tcaacgaaac acggaaaaaa atctccgcga atcgtgccga gcaaaaggca
    24001 gatcaaatca tccactatgc acagtgtgcc tatccagctg ttgaaaaaga cagtatccac
    24061 tgtcaaaaaa cgatctatta cgctgaactt ctccaagatt tactcgaaca aaaagaagca
    24121 ctggcgacac aaatgatcaa aaaagccgaa ggctctcctt gctttttgtt gtaccaaacg
    24181 ttccctggga ttggcgcact cacagccgct ttattgctcg gtgaattagg agatatcaca
    24241 cgatttaaaa cccataaaca attgaatgcc tttgtcggaa tcgacatccg acggtatcat
    24301 tcaggtaagt atactggcca agaccgcatc aataagcgtg gtaatcccaa agcacggaaa
    24361 attattttct tcaccattcg aaatatgatt cgccagcaac gcgcagctcc taatcatatt
    24421 gtcgattatt actacaaatt aaaaaagcaa cctatcccta agaaagataa ggttgccaca
    24481 gttgcttgta tgaacaagct tctgaaatgt atgcacgcta tggttagggc acatacagag
    24541 tacgactatg cgtacgcggt ctcagtggac cattaactaa accacttaca gtataccact
    24601 tctttgccca gatcgaaaat tttttacgaa cggggcttta tttggtgtgc cttgattttg
    24661 tcgctttcgt ttatgagcta tttttcttac accttttact tgactaatcg taggaaaggg
    24721 aactgtgaca aaagtcttgt cgcagttcct ttttccgaat aaacggtgct caaaagcttg
    24781 catctgcggt aataagtcca accaagttaa aaacataaaa agctgttttt acttggctgt
    24841 tcttattact tgatgcaagg cagctttttc acaacctctg atacacggtg ttccagaagt
    24901 aacttcttcg gaaataagcc gaaatttcac aaaaatttga aaagcaattt tcttaaattc
    24961 cttcttattt cttgaagctg cccacttctg acacaacctc ctttgtgtaa aagaatcagt
    25021 ttctactcga tttcttctat cgtttcctgc aaacgctgtt catatttttt gtttccttta
    25081 tataaatcac caatcgtcca tgccaacagg agaaggacaa gaacaatgat tacataagcg
    25141 atttgatcag ccaatgctag ttgagctgag gtggcttgct cgccgaagaa actttcgatt
    25201 tgacctggta atcctcgtaa attcaagtaa gtcagactaa tcacagagaa ccagccaagt
    25261 agttttacaa caaatgaatt tttgaatcgg ctccccatct ccgcttggct attggtcatc
    25321 atcagtaaag gaatcatcga gaatggcaat gcaaaagcca gaaaaacttg ggattcattc
    25381 atcaagttat tcaaagcggt atgttcttcg atcgttcctt ttgtacttgt aaacaaaaca
    25441 caaatcaata caggaatcac agaaagcaat cgtgtgacta gtcttcttag ccaaattggg
    25501 atacgcatat ggatgaagcc ttccatgatg acttgaccgg tcaacgtacc agtaatagta
    25561 gagttctggc cagaagcaag aagtgctaca gcaaataaag tagacaagat accagatttt
    25621 gctacagcaa tcaagatacc attgctcata gctgatggat cagataaagc ttcatacaga
    25681 ccaaaaaagg aaggatcttg gacagaaccg gttttgaata cagccacacc catgatcaat
    25741 agcagtgcat tgactagaaa agccattgac aactggatat tagaatccca agtagaaaag
    25801 cgtaccgctt gtgctacatc ttcttcgtct tggtgatcga tcttccgagt ttgagaaact
    25861 gctgaatgaa gatataagtt atgcggcatg actgttgcac caataatccc taaagctcca
    25921 gtcagcggag tttcgccgcc gatgaccggt gagtctgaga atgtgtgact gttagggata
    25981 aatccggcaa acaaactgtg ccaatcaggg ttagacaagc caacttgata gacgaaaacg
    26041 aataaaatga cgaaaatcaa gcagacaacc aaagcttcga ttttacgaaa cccgactttt
    26101 gtcagcaata aaaggacgaa aacatctaac acagtgataa atacggcaat taccaatgga
    26161 atatcaaaaa gcaggtagag ggcgattgct gcaccaatga cttctgcgat gtctgttgcc
    26221 ataatggcta attcagtcaa gatccataaa atgacaccca atgtcttact tgtccgtgct
    26281 cggattgctt gggccaaatc catttgggtc acgattccta attttgctgc catatattgt
    26341 aaaagcatag caatcagact agacatcaaa ataactgaca tcaataaata ttggaaattt
    26401 tgtccaccag tgatcgaagt ggaccagtta cctggatcca tataaccaac tgctactaat
    26461 gcacctggtc cagagtaagc aagaagtgtt ttaaaaaaac tttttccctt gggtacatcc
    26521 actgttccat ttacttcagc taaagataaa ccatttgtat gttcaataag tcgatgctta
    26581 tgaaattgtt tgttggattg attattcaag aaaaaaccac ctttcctatt tatctacgat
    26641 tacattctac acctcagaaa gaaaaaatta aagaaaaaga tttggtatgc ctaatttttt
    26701 ttcgtggcgt gtcttgctgg ttaatgaaag aaattttgtt cttctctaaa aaaaccacta
    26761 ttttttgcat gaaactaaag aatacgcctt tcttttttca ataaacttta gtaaaataaa
    26821 tcattgagag caattcggaa atagaaagga gagatttata tggtatcaac aggtattgtc
    26881 gtacttattg ctattattgc tttgctaatc ggcgcagtag gtggcttttt cctagcgcgt
    26941 aaatatatga aagactattt agaaaaaaat cctcccgtta atgaggacat gttgcgatca
    27001 atgatgatgt caatggggca aaaaccatct gagaagaaaa ttcgccagat gatgcagcaa
    27061 atgaagaacc aagggaaaaa ataggttctg acccaaagac tttttgcggg ctgatttttt
    27121 cagtccgttt tttatttcgt aatttgttag actattcaga ctattcagca aaaaagacaa
    27181 gcacagacaa tcctatgctc ttgataaaga caaaggagga gtaaaatgtc gatttttaga
    27241 aaattaggtt ggttttttcg acaggaaaag aaacattatt taattgggat tttctcccta
    27301 ttcgcagtgg ccttggtaca gttagctcct ccaaaagtga ttgggatcat cattgatgag
    27361 atcgccgata aaaatttatc aataaagatc atttcctggt ggatcttatt attgatcctt
    27421 gcagctctct tacaatatct ttttcgttat atctggcgga cgaatatttg gggaagtgca
    27481 gctcggttgg agaaagaact tcggcagcag ctattcaaac attttacaga aatggacaat
    27541 ctcttttacc aaaaatatcg gactggagat ttgatggctc atgcaacgaa tgatttgaat
    27601 gcaatccaaa atgtagcagg agctggtatc ttgacctttg cagattcagt gatcacgggc
    27661 ggaacaacga tcattgcgat gattttgttt attgattggc gcttaacact gattgcgctg
    27721 attcctctgc ctttactagc cgttacttca cgagtgctgg ggtcaaaact ccacgatgct
    27781 tttcgtgatt cgcaagaagc tttttctagt atcaatgata agacacaaga aagtattact
    27841 gggatcaaag tcattaaaac atttggacaa gaaaaagaag atctcgcgga ttttgaagaa
    27901 aagattgaag atgcaattat taaaaacaaa cgagtcaatt ttttagactc cttatttgat
    27961 ccattcatta ccttgattat cggtctgtct tatgttgcaa caattatttt aggtggaaag
    28021 tatgtcttgg aaggcacgat ctcaatcggg cagatggtct catttattag ctatatcggt
    28081 atgcttgttt ggccgatgtt tgcgattggt cgattgttca acgtattgga aagaggaaat
    28141 gcttcttatg atcgcgtcaa tgaacttttg catgaaaaga cgcatatcgt ggaacaactg
    28201 ggtgcagtgc agactccggc aaaaggcgag ctgaatgtag ctatttcctc ttttaactat
    28261 ccgaaagaag aatcaccagc attagaacaa atcaaatttg cgatccaaga aggagaaaca
    28321 ttaggtattg ttgggaaaac tggtgcggga aaaacgacaa tcatcaaatt actgatgcgt
    28381 gaatacgatg attatcaagg aaaaattcaa tttggcggat gttcgatcaa agaatattca
    28441 ttgaatgctt tattaggatc aatcggctat gtgcctcaag atcacttctt gttttcgatg
    28501 accattcgag ataatatccg tttttctaat ccaaaacttt cagaagaaga agtagagcat
    28561 gcggcttctt tagcatttat caacaatgaa atcaaggaat taccaaaagg ttatgatacc
    28621 ttagttggag aacgtggagt ctctttatct ggcggacaga aacaaaggat ttcgattgct
    28681 cgagcattga tcaaaaatcc tgaattgctg atcttagatg atgcactttc tgcagtagat
    28741 gccaaaacag aagaagctat cttgcataat ttaaaagaaa taagaaaaga gaaaacaacc
    28801 atcattgcag ctcaccgttt aagcagcgtg atgcatgcaa aagaaatcat tgttgtcgat
    28861 caagggaaaa tcattgaacg aggaacccat catgagctgc ttgcattagg cggctggtat
    28921 gaacgaatgt gggagaaaca gaaattagaa gcgaagatag aaggaggcga ggcctgatgg
    28981 atgaaaatta tcaatcggaa tggacaaaat cgattccact taaagaacag aagaagatca
    29041 tcaaacgact gatgaagttc gccaaacctt ttagaagaac gttcatcgtt gctatcttat
    29101 ttgcgtttgc cctgtctgtg atcaatgtcc tattgccaag gatcatccaa acttttatgg
    29161 atgatcatct ggctaaacag tcggctacga cacaagttat tttgtttttt gctggtatgt
    29221 acttgtttgg agtcatagtc aaaagtatca tttggttttt ccaatggtat ttgtattcca
    29281 tggcttcatt gaagacctat cagtatgttc gggtaagatt atttgaaaag ctgcatacac
    29341 taggtatgcg ttattttgat cagacaccgg caggatcgac tgtttctcga gtgacaaatg
    29401 acacagaaac gctatttgaa ttttggtatg tctttttgat ggtattgact gggatctttg
    29461 cagtcgtttc ttccttcatt gccatgtttc aaatcaatgg agaaattgcc ttgtggactt
    29521 tggtgttctt gccgatttta ggaatcgtca tctggtatta ccagaaattc agttctcgta
    29581 tttaccggaa tatgcgggaa aaattaagtc agctgaacac gaaattgaat gaatcgattt
    29641 ccggcatgcg tattatccag cagtttcgcc aagaagctcg tttagctaaa gaatttgaac
    29701 aagtgaacaa cgagtattta gacacgcgct atgcgatgat caaaacaaat tcgattctgt
    29761 taagtccgat catcaatttt ctatatgcat tggcgattgc gttggcgttg actttgtttg
    29821 ggatcgatgc gctgcattct cccgtagaag ttggactgat ctatgcattt acgacctatg
    29881 tccagggatt ttttaatcca atgtctcaaa tgatggactt tttgagcacc tttacagatg
    29941 gaatggttgc cggtagtcgt attttgaaaa tcatggatac agaagaatat gcaccgcaac
    30001 aaaatcctgg agcagatcaa gcgattactt caggtaagat cgagtttcgc aatgtaagct
    30061 tttcttatga tggagagcac aatgtattga acaatatctc ttttgtcgct aatccgggag
    30121 agaccgttgc attagtgggg cacaccggaa gcggaaaaag ctcgatcatc aacgtattga
    30181 tgcggtttta cgaattttat gaaggccaga tcttgattga tgatcatgac attcgagaat
    30241 atccaatgga agagttacgt aagaaaatgg gattggtctt gcaagatgcc ttcttgtttt
    30301 atggagatat cgcaggaaat atccggatga tgaatccaac tatcacagac gaacagattc
    30361 gccatgcagc tgagtttgtt caagcaaaca agttcatcga tgaattacca aaaggatatc
    30421 actcaaaagt gatcgaacac ggtgccagct attctagcgg acaacgacag ctgatcactt
    30481 ttgcgcgaac aatcgtgaca gatcctaaaa tactagtatt ggatgaagcg acagcaaata
    30541 tcgatactga aacagaagga ttgatccaag aaggattgac aaaaatgcga caaggacgga
    30601 caacgattgc gattgcccat cggctgtcca cgattcggga tgcagaattg attttagttt
    30661 tagacaaagg tcatatagta gaacgtggga atcatgaaac acttctagcg caaaatggtt
    30721 tgtatgcaga tatgtacaaa ctgcaaagca gtggtgtgta aaaagtggtt gtgacagggc
    30781 tccgttcagc tttaggtgat aagaaaaaaa ttgtaaaaaa ggctttccag atttttgcat
    30841 aaatttggct tatcaccgat aagctggtac tggaacaccg tatattagaa gttgggacag
    30901 tagcatagta gcattttgac ctaagcgcta gagtgaaaat aaaacagagc ttcccagatt
    30961 cttcatctgt gagcgttagt gtcgtaatta ccagatttaa aaaaaatcac gacagctagt
    31021 cagaagtgcc caatagccgc taagaaagcg ttgacaaaag tgcttgcttt cgataatata
    31081 aagaaaacga tacaacttgg atagtgattg cctgatgcaa gctaaacctg atgagtctcc
    31141 catggttcca tggacggctt tttgggtttt tctttttgtt ttggatacag ccctatatat
    31201 catggaaagg agtaaaacat gctgattgag aaagtactga ataacaacgt cgtaataacc
    31261 agggatgaaa gaaatcagga aatgatcgtg atgggaaaag gtttggcatt caaaaagaaa
    31321 gtgggtgacc cgatttttga ctcatgcatc gacaaaaaat ttcagttgac aaatgacgga
    31381 ctttcacaac agttccaaga attggcacaa gcgattcctc ttgagtactt agaaatttct
    31441 tgtgaaatca ttgaatatac aaaagaggct ctacaagtcc agttgaatga ttcggtgtat
    31501 attgcattga cggatcattt gtatacggct atcgaacgtc acaaaatggg aatatttgta
    31561 ccaaatgtat tgctgtatga tatcaaacaa ctatttccta aagagtatgc catcgggaaa
    31621 aaaacagtga agaaaatctc ggataaatac cacatcaagt tatcagaaga tgaagccgga
    31681 tttatcgcat tgcatttagt caatgcacaa ggcattcaaa gccaacaaga caatacctac
    31741 ctgtttacta caacaataca ggatattcta aatatcgtcc gctattacta taagattaca
    31801 tttgatgaag attcagtcca tttttttcga ttcgtcacac acctacgttt ttttctgaca
    31861 cgcgtcctag atggagaaaa atcagaagtg ggagaagttt ctgaggaatt gtaccaggtt
    31921 attcaaaaaa aatataagga tacgtttggt tgcgttgaga aaatagcaga ctttttagcc
    31981 gagatattca actaccagat gtccacggac gaaaaaatgt atttaacgat ccatattgcg
    32041 cgtttagtgc atgagaatcg ttgtaaataa ataaaaaaag gaggataaat taacaagaac
    32101 gcatgaaata agggtagtga cattcagttg gctaaacctt ccactaataa attggaggga
    32161 atagaaatgg gaaaatatca agaattagcg agcaaaattg tagaaaatgt cggcgggaag
    32221 gaaaatatca atggtttgac acattgtatc acaaggcttc gtttcaaatt aaaaaacgaa
    32281 gaaaaagcaa atgatgagat cttgaaaaat atggacggtg ttgtgacggt aatgcgagcg
    32341 ggaggacagt accaagttgt catcgggaat catgtgccag tcgtgtttga agaggttata
    32401 aaagcaggaa accttacttt tgatgaggct gtttcaacag aaaaaatgag accgtttgat
    32461 atgcttattg atggaatatc gggctgtttc cagccattcc ttgctattct agctgctggt
    32521 gggatgattc gtggactgac agcattactt gtcttcttag gcgcatttga ccgcggttct
    32581 ggcacatttg ttatgtttga taatatcggt gattctgtat tccaatttat gcctgttatt
    32641 atcggtttaa cagctgcccg taaatttaaa gtaaatgaat tcgtagggat gttgcttggg
    32701 gcagcattaa tgaatcctag cttgtcgctg gaagctttga gtggtgcagc agaagcacca
    32761 ctgactacca tattttctgg cactattttt gaagcaccta tttatcaaac agtattcggc
    32821 attccctgga ttgcgcgtaa ctacgcttct tctgtcattc ccattatctt tattgtgttg
    32881 ttagctagcc aaattcagaa accaattaaa aagttagtac ctgagatgat cgcgaatttc
    32941 ttcgttccat tcttcaccgt tcttattaca atgcccttag gttttttact cgttggacca
    33001 gcattcacat tcgcaactga tattttaatg gctggatttg aaacactttt agcactttcg
    33061 ccagttattt atggagcaat cgtaggcttc ttctggcaaa ttctagtgat gtttggtctc
    33121 cattgggcaa tcgtaccaat gggattgatg caattttctg tgaatggttg gcaaaatatc
    33181 atgacacctg ttgcagtagt gtcttttgga caaactgcag cacttactgc actctacttt
    33241 aagcttagaa acccaaaaga caaagcaatc gcaataccag ccattgtttc tggtattgtg
    33301 gggattacag agccagctat ttatgggttt acattgccac gtaaaaaaat atttattttt
    33361 acctgtgtcg gtggtgcgtt agggggcgcg tatagtggat taatgaattt aacttcttgg
    33421 aatccaggtg gattaggcat ctttacaatt cccaactata ttagaccaga tggtgattta
    33481 acggatgtga ttaatgtatt gattggaatc gccattgcga tggtggtatc ctttgcgctg
    33541 acttttttct tttggaagga ggaagcaggt gaaacagatg atagacagaa aagatcaggt
    33601 aaagaaattg taaaaacacc gatacaagga caaatcgctc cactgaatgc agcaaaggat
    33661 gcagcttttg cacaaggaac actaggtcga ggaatcttga tctaccctga aaaaggagaa
    33721 gtacgtgccc cttttgacgg aacagtcatg accctgttcc cgacgaaaca tgcaatcgga
    33781 atggtttctg aagcaggtct ggaattgctg attcatgtcg gattggatac tgttcagttg
    33841 gaagggaaat attttgaaag cttggtgcag caaggagaaa gagtgaaaca aggcgatctg
    33901 ttgctccgct tcgacaaaaa gaaaatcgaa gaggaaggat acagtttaga aacacctgtg
    33961 atcgtcacca attacacgga ttatttggat attttggaaa atcaagggga gacggtcggg
    34021 ccagacgatg cacttatcac cgcactgacc tgaacggtta ggtgaaagaa tggactaggc
    34081 ttaattattc tttttagtcc acttctttat tttcaaaatt gaaaggctct ttcatgatgg
    34141 ctgagctgat agggcgttta tcaaattttt gtcctacaga aattagatgg actaaattct
    34201 gttgataatt ttctgcaaaa acacaactat ataacacgtc tagaagataa caaatcgatg
    34261 tattgatcgt aaaattacca attttcgaat acagtcgttc gcgtgtcgta agtcgcaaag
    34321 cggctgtact cattgaagat agcgttgaat caccgatact ggtcaaagct aaaattggaa
    34381 catgattttg tttcaatatt tctgcggtac gaaggatcac attgttttca cccgtataag
    34441 aaatcagaat cccgcacata tcactcgtgc aattgtacgc ttcatagaac gattcaccaa
    34501 aagtggtgac aatcgtgaca tccattttga tgcgcttcat tttcagcatg aaatcttgag
    34561 aaatcaaagt attcgagtta ctggcgaaaa tcacgatttt ttttgcttga agcattagtt
    34621 gtttggcttt ttgcagttgg tcatgatgaa tgagagaaag tgtatcttga atcgtcatct
    34681 gttctaaaga agccatttta tttgcgatcg tcataatacc gtctgtggtg gaaaaaggaa
    34741 gattcgcatc tacgtcttga aaattccctt caagataggc tgtttcagct aaaaaagcat
    34801 tacgaaaact gacccagcca tcaaaaccca ttttttttgc tacacggatg agtgtggacg
    34861 ggtggacata acatcgctca gcaatctctt ggatggtcat ttcgccaagt gctggagaat
    34921 cgcttaagag aaactgaatc acttcatttt ctgaaggaga aaaggagatt tctttgattt
    34981 tttcacgtaa taacatgtag ataccttctt cttgtttttt tacgtaaatt ataacttttt
    35041 tgaaaatgat ttgtaaacgg atttatgtta tatagcttaa taaagacatt ttttgacaag
    35101 atatttacaa aaatccagta gaaaacacta acttttgtaa atgttactgg aaagaaacga
    35161 atttctattg tttgttttgt ttacaaaaaa gataataaaa gtgtaaaaag taaaggagtg
    35221 agaacatggc aaaaggaatc aaaatcgcta cgattggtgg aggcagcagt tacacccccg
    35281 agttgatgga aggatttatc aaaagatatg aggaattacc gatacgagaa atctggctcg
    35341 tagatgtaga agaaggaaaa gaaaagcttg agatcgtcag tcagatgtct cagcgtatgt
    35401 gggatgcttc tccgtatgaa gtcaaaatct atgcaactct ggatcgggaa gaagcattga
    35461 aagatgcgga ttttgttacg actcagtttc gtgtcggtca attagatgca cgaatcaaag
    35521 acgagcggat ccctagttat tatgggatga ttgggcaaga aacaaatggt gctggcggga
    35581 tattcaaagc ttttcgtacc gttccagtgg ttttggcaat cgttgaagac atgaagcgtt
    35641 tatgtccaaa tgcttggctg atcaatttcg cgaacccaag cgggatggtg acagaagcag
    35701 ttatcagata tggcaaatgg gataaagtga taggattatg caatgtgcca gtaatggcga
    35761 tgatgacaga accaacaatg cttggcaaga aaaaagaaga gctgatctac aagtttgccg
    35821 gtctaaatca cttccattgg cacaaagtag cagataataa aggaaatgac cgcacggcag
    35881 aattgattga tcgtttatac gatgaagaca atggattgcc gaaaaatatc tttgatatcc
    35941 cgtttttcaa agaacaatta aaacaaatga acatgatccc ttgtggctac caccgctatt
    36001 actaccgtga agaagaaatg ctggaacatg ctttagaaga atatcaaacg attggtacaa
    36061 gagcgcagca agtgaaagaa acagaagcag agctgtttga attatacaaa gatccagaat
    36121 tggatcataa acctgaacaa ttgcaaaaac gaggtggtgc ttattattca gatgctgcct
    36181 gtgaaacgat tgcttcgatc tatggaaata aagaaacaca gatcgtggta tctacaaaga
    36241 atgatggagc tgttcctgat ctgccggcag attgtgtagt agaagtcact gcctatgttg
    36301 gcgcacaagg cgcacgaaat gtagcgtttg gttcccttcc tgctgctgaa agaggctggt
    36361 tgcaagtaat gaagaatatg gaattgctga cgatcgaagc agctgtgact ggtgattatg
    36421 gaacagcttt acaagcgttt acgatcaatc cgcttatacg atcaggaaag acagcaaaac
    36481 ggatcatgaa tgagttgttt attgcacatc agcagtattt accgcaattc aaggaaacaa
    36541 tcagccggtt aaaagcagaa ggaatcgaag tccaagatga actggcaaga gaattatcaa
    36601 gcaatacaca tgtaatggag gaagtatgat gggattcaga aaagattttt tatggggcgg
    36661 agctacagca gccaatcaat gcgagggcgg ttatgatgaa ggcggacgtg ggttagcgaa
    36721 cgtagatgtt gtgccaatcg gagaagaccg ttttcctgtc attactggaa aaaagaaaat
    36781 gtttgaattt gatgaaaatc atttttatcc agcaaaaatt gcgatcgata tgtatcatca
    36841 ttataaggaa gatattgctt tatttgcaga aatggggttc aagacttatc ggatgtccat
    36901 tgcttggagt cgtatttttc caatgggcga tgaaaaagag ccaaatgaat ctggtttgaa
    36961 attttatgag gatgtcttta aagaatgtca aaagtacggg atcgagccgc ttgtgacgat
    37021 tacacatttt gattgtccga tgcatttgat caaagaatat ggtgcgtggc gttccagaga
    37081 actcgttggt ttttatgaaa atctgtgccg agtcatcttc aatcgctata aaggacttgt
    37141 caaatattgg ttgacattca atgagatcaa tatgatcctt catgcaccat tcatgggcgc
    37201 agggctgtat tttgaagaag gagaaaatga agaacaaatc aaatatcaag cggcacatca
    37261 tgagttggtt gcaagtgcca tcgcaacgaa gattgctcat gaagtagatc cggagaacaa
    37321 agtaggctgt atgctggcag caggagcata ttatccatac acttgcaatc ctgaagatgt
    37381 ttgggcttct agaaaatcag atcgagaaaa ttatttcttc attgatgtcc agtcacgagg
    37441 agaatatcct gcttatgcat tgaaagaaat ggaacgaaat ggcattcaga tcaaaatgga
    37501 acctggggat gccgcattgc tgaaagaaca tactgttgat tttatctcct tttcttatta
    37561 ttcttctcga gtttcgacta ctgacaacga actcttggaa cagactgcag gaaatatctt
    37621 tgcttctgtc aaaaatccat atctggaagc aagtgaatgg ggttggcaaa ttgatccatt
    37681 aggcttgaga ataacgatga atgatattta tgatcgttat caaaaaccac tatttattgt
    37741 agaaaacggc ttaggtgcag tcgatacgcc cgatgagaat ggttatgtgg aagatgacta
    37801 tcgaatcgac tatctggcag cacatatcca ggcaatgaaa gatgcagtag aattagatgg
    37861 agtcgatcta ttaggctata cgacttgggg atgtattgat ttagtatcag ctggtacagg
    37921 tgagatgaag aaaaggtacg gattcattta tgtcgatcgt gacaacgaag gaaatggcac
    37981 attagcccgt tcgaagaaga aatcattcaa ctggtataaa aaagtaattg attcaaatgg
    38041 agaaaatctt tcgaatgatt gatcaatgat ttataaaagt ctattgtttt tcagcggatt
    38101 tttcgagtat aataaagcta ttcgagaaac gcaagcagaa caatagactt tttttcgcat
    38161 tggctgtaaa gtatgcttac ttgattaagt aaaggagaat ctacatatgt atgatgtaat
    38221 cgttattggc gcaggtcctg ctgggatgac tgctgcttta tatgcttcac gttcaaactt
    38281 atccgtattg atgatcgaac aaggcgcccc tggcggccaa atgaacaata cggcagaaat
    38341 cgaaaactat cctggtttcg attcaataat gggtcctgat ctagcttata agatgtatga
    38401 aggtgtttca agatttggga cagaaaatgc ttatggaatc gtgcaagata tcaaggatca
    38461 cggcagccac aaagaagtta tttgtgaaga taaaacttac gaaggaaaaa cagtcattat
    38521 cgcaacaggc tgtatccacc gtaaattagg cgtacctggc gaggaagaat ttgctggacg
    38581 tggcgtttct tactgtgcag tttgtgatgg tgcgtttttc cgtaacaaac gtctagtagt
    38641 gatcggagga ggagactcag cagtagaaga agccatctat ttgacacaat ttgcttctga
    38701 agtagtcatc gtccaccgta gagatgaatt acgtgcacaa aagatcatcc aagaccgtgc
    38761 atttgcgaat gaaaaaattt cctttatgtg ggatacagtc gttgacgaaa tcgttgggaa
    38821 tgaaatggta gtgacaggtg tgaaagcacg taatgtcaaa accggcaatg agtttgattt
    38881 ggcagcagac ggagtattca tctatgttgg actggatcca ttaactgcac catttagaga
    38941 agcagggttg acgaacgaag ctggctggat tccaacagac aacgaaatga agacgaatat
    39001 accaggcgtt tttgccatcg gagatgttcg tgaaaaagat ttgcgacaaa tcactactgc
    39061 tgttggtgat ggtgggatcg ctggacaaca agtgtataaa tacttggaat ctttagaaga
    39121 aacaactgca taagtttaaa aagagtggaa gaacggttta attgttcttt tactcttttt
    39181 tttcgcgtga aatctactga atccgattta tgcgaatact tgcaaccgtg cttgataaaa
    39241 gaatcctttc ttgatttaag cgttttttgg tcctcatact ttcatatcta ataagtgaat
    39301 gctatactta ttaagaacca tatttcagaa agaggtgtta ttttcatgtc ttgggaacaa
    39361 gtgtatgaac aatgggtaca tgaagaaaat ttagaagaaa acttaaaaaa acaattaaat
    39421 gatctgggtg aagatcctga aaaacttgaa gatgcttttt atgcaccgtt ggaattcggt
    39481 actgcaggca tgcggggaat cttagggcct gggatcaatc gaatgaacat ctatacggta
    39541 agacaagcaa cagaaggact tgcacgtttc atggatacac aaggcgaaga aacaaaacgc
    39601 cgaggtgtcg ctatcgctta tgactcacgc catcaatcac cagaatttgc catggaagca
    39661 gccaaaacat tagcacatca caatatccca tcttatgtat tcgaaagtct acgtccaaca
    39721 ccagagcttt cttttgcagt ccgtcatttg aagacgtttg cgggaatcat ggtaaccgca
    39781 tcccacaatc cagcagctta caacggatat aaagtctacg gagaagatgg gggacaaatg
    39841 cctcctgcag acgcagatgc attgacgaaa tatgtccgtg aagtcagcaa tccgttaaaa
    39901 gttgaagtat tatctgacga agaagctgaa catagcggat tgatcacgat catcggagaa
    39961 gaagtggatg ccgcttatct agaagaaatc aaagcagtaa cgattgatca tgaattggtg
    40021 gaaacaatgg ggaaagattt gaaacttgtg tacacaccac ttcacggaac aggaaaaatg
    40081 ttgggcgaac gtgcgttgaa acaagctgga ttcgaacaat tcgtactagt tccagaacaa
    40141 gctgtcgcag acccagattt cactacagtc aaatcaccaa atccagaaga acactctgct
    40201 tttgagtatg cgatacgact tggcgagaaa gaaggcgctg atttgctgat tgcaacagat
    40261 cctgatgcag accgtttagg tgcagccgtt cgtttgccaa atggctccta tgaagtattg
    40321 accggaaacc aaatcggagc actgtttgct caatatattt tggaagcaca ccaatcgcga
    40381 ggcactttac ctgaaaacgc agcggtattg aaatcgatcg tttctagcga attacctaca
    40441 gcaattgcgg aacactatgg ggctaccatg ttcaatgtat tgacaggatt caaattcatt
    40501 gctgaaaaaa ttcaacaatt tgaagaagat cattcccata cttttatgtt cggattcgaa
    40561 gaaagttacg gttatttagt taaacctttc gttcgcgaca aagacgcgat ccaagcattg
    40621 ctcttattag cagaagtagc agcttactat aaaaaacaag gcaaaacgtt gtatgatggc
    40681 ttgcaaacga tttttgaaac ctatggctac tacgcagaaa aaacgatttc tgtgacaatg
    40741 agcggacaag aaggttctgc gaaaatctct gctttgatgg aaaaattccg tgaagaagca
    40801 ccaacagaat ttgccggagc aaaagtcatc caaacagaag acttcaaaga gttgacgaga
    40861 acagaccgtg aaggaaacgt agaaaaacta acgacaccgc catctgacgt attgaagtat
    40921 acgctggaag aaaatggctg gatcgctatc cgtccttcag gaactgagcc gaaaatcaaa
    40981 ttttatatcg gtgtaaaagg aaactcttca gaagacgcag ctgaaaaagt agccgcttat
    41041 gaaacgatta tccaaaagat gacagaagaa taaaaaaact tgagactgat ggaaaaagtg
    41101 gtaaacttta gaagtcagtc ttttttcaag ttggaggtga atggattgcc agacacgcaa
    41161 aaaacaaaag tagagaaagt cagccaacta ttcaaaatgt tgagtgaccc cactcgtctc
    41221 aaaattctgc tgtatctgaa agacggggaa caaaatgtga cagcaatcat ccaagcagtg
    41281 gaaatggaac aatctgctgt atcgcatcaa ctgcgtttat taagagaaaa ccatgtcgtc
    41341 aagtcccatc gtgagggaaa agcgattttg tatagtcttg atgattctca cgtactggat
    41401 attttgaacc agacactcaa acatgtggaa catcaataac gataggtgca aatagagaca
    41461 aactggactg tgtcaacgaa tcttcttcgc tgacacagtc cagttttttt aaagaaaaat
    41521 tgttagtctg tttcttcggt ggtttcagtt ccataataac tatggtcttc taggtctaaa
    41581 gcattcaaaa taagcgaagc tgtttcttca atagataaag aagcgacatt gattactacg
    41641 cagcccaatt tttcataaag atcattcgca aaatcgagtt cagctcgtat tttttcgata
    41701 tcggaataag cagtatcagg atttaatccg taagagcgca tccgttcttt acggatattg
    41761 tttaaaatat ctgggttatt cgtcagtccc acgatttttt taggatcgat ctcccaaagc
    41821 tgtttgggaa tatgtgcttg tgggatcaaa ggtagattgg caacttttaa atttttgtta
    41881 gctaaaaaca agctcaaagg cgttttggaa gttcgggata cgcctagcaa aacgacatct
    41941 gcttctagaa acccacgagg atctttcccg tcatcgtatt ttacagcaaa ttccattgct
    42001 ttgatccgtt tgaaatagtt ctcattcaat aaatgaaggg cgccaggttg ccgaatgggc
    42061 ttgataccag ttaagcgctc gatttctgat atcggcggag tcatcacatc aaaactaaat
    42121 aattgatgtt cttcacaaaa agaacgcgtc atctcgatca attcttgatt gatcaatgtg
    42181 tgcaggacaa gagctttttc ttctagtgca tcttgcagtg cctgcatcaa tgttttctca
    42241 tctgtcacaa atgttctgcg gaataaattg aactcaacgc taggatattg ggccatagtg
    42301 gcttgcgcta gttttgtcgc agtttctcca gcagagtcgg agatgacaaa aaaagtaacg
    42361 atttctgtag aatcggaaga catggataaa acctcacttg catttttttt atgtttatta
    42421 taccatactc tagaatgtgt acttcgtaat cattttgatt tggaggaata agtcatgaaa
    42481 aaacagacgt tgatcgaaca atcactagaa acattgaaaa ataacggttt taaatatact
    42541 aaaaaaagag aagcattgtt aacttattta gtgaagcgca atcgctacgt atccgctaaa
    42601 gaagtttttg actatatgaa tcaggaattc aaaggagtaa gttacgatac gatttatcga
    42661 aatctccatg attttgcaga aatcgattta ctggaagaaa ccgatttaaa tggagagatg
    42721 aagtttcgtt ttcattgctg tcaaggggaa atcggccatc accatcactt tatctgtacg
    42781 gtgtgcggaa caacgaaaga aatccatatg tgtccaatga attatttcga agaacagctc
    42841 ggtggatgta cgatcgaagg gcatagattc gagattttcg gaagatgtga aaattgtcaa
    42901 taaggattta aataaaataa catttgataa ttttaaaaaa aagcaagatt tccttgacgg
    42961 tcaaaacagc attagatata atatttacag gacagtcttg ttttttgaga tatatttcaa
    43021 taacaattac ggttactttt taagctcgga gggagggaat taacatgtca aaaacagtcg
    43081 ttcgcaaaaa cgaatcactt gacgatgctc ttcgtcgctt caaacgttcc gtgtcaaaag
    43141 cgggtacttt acaagaatct cgtaaacgtg aattctacga aaaaccaagt gtaagacgca
    43201 agaaaaaatc tgaagcagct agaaaacgca aaaaattcta gttctgtgat gaattggagt
    43261 tggtagtgtg tcactactaa gtagattaaa cgatgacatg aaaacagcga tgaaagcgaa
    43321 agataaggaa tctttacaag tcatccgaat gatcaagtca tctatacaaa acgagcagat
    43381 taaagaaggt cacgacttga cagaagaaga agaattaacg gtgttgtctc gcgaaatgaa
    43441 acagcgacgt gattctttgc atgagtttga agaagcagga cgtgacgatt tagctgaaaa
    43501 agtaaaaagt gaaattgtga tagtcgaaaa atacatgccg gaacaacttt ccgacgaaga
    43561 aattcgacaa cttgttcaag aagcaatcac gcaaactggt gcttcatcaa tgaaagaatt
    43621 tggcaaagtc atgggtgcga tcatgcctaa agtcaaagga aaagcagatg gaaaccaagt
    43681 aaatgccatt gtgaaagaac tattacaatc ttaattttat catttaaact gcggacaatc
    43741 attgtccgca gtttttttgt gctcgtaaaa aagagatcta aaaaatagct agacgaaaga
    43801 ataggattct ttcatctagc tgtttttttc ctgtttaata tttcttatgt taaattgtgt
    43861 ttgatctggt tattcttctg gtagttcatt tgcttcttgt ttataccctg ataggcgata
    43921 ggcgtaatag aagagtaagc tgccagcata cccaagtaac gttgggacca tccagccaag
    43981 tcccaatgca gcaaaaggaa cgtgatgatg ataaaattcg agcatgcttg ctacaactct
    44041 ttgttgactc actaaagcag gcgaatttgc cagcatatcc aatacggcgg gaacagcagc
    44101 aaacaacatc gttacttgat agacaaatgg tgtcttttgg aaaaattttg ctgttaagga
    44161 aagcaaaatc aacgcaagcg acaatggata caaaagcatc aatactggta aagaccattg
    44221 gatgatattg tccaaaccag catttgcaac gacaaaagag acgaaagtcg ttaaccgcag
    44281 ccatgtcata taactgactt tagggaacag tttatggaaa tcttgtgcaa aagaaacaac
    44341 gagtcccata gcggtagtga agacacctaa tgtgaccatc actcctaaga agctagcgcc
    44401 gaagttacct aaataaaaat tagtgatctg agaaagtgca gttccgccat tttctgataa
    44461 agacatctta ttcaaactca tcgcaccgag aagaacaaga ccaaaataga tcatgacttc
    44521 tagcgcaacg ctcaggctac cagcttttgc tgttaattct gtgacttttt tatctttgaa
    44581 accaaggtca cggactgcat ggacaaaagt gacacttaag gcaagcaagg ctactgcatc
    44641 aaccgtgtta taaccttcta ggacaccatt tgttaaagcg tttgtttggt aagtatctgc
    44701 agcagattga tttagatttc ccattgggtg gaataaagaa acgacaaaaa tgattgctaa
    44761 taatgcaaga aacaaggagt ttagatactt tccgacgtat ttgaccaacc gtgtgggatg
    44821 gacagtaagg aaataagcaa gtaaaaagaa aagagcagag aataaaaaca tacctaatga
    44881 attatatttt tcaggcaaaa atggtttagc agccatttca aaagcagtag cagctgtccg
    44941 tggtgtaccg aaaaatggtc cgatcgtcaa atgaacaagg attaagaaca aggcagcata
    45001 ccattttccg acaggtttag ctaagtcata cagaccatca ctttttgtca ctactacagc
    45061 taagatagct agtaatggga aaagagcgcc tgagatggca aatcctacgc cagcactgac
    45121 ccagtttgcg ccagccattt gacctaagtg gacaggaaag attagattac ctgacccgaa
    45181 aaacatcccg aagataagtg aactgaccat caatagttgt ttccatgaat aagtttttgt
    45241 ttcttccata aatttttcct ccaataatta tcattttgat tgacgatata aacgttgcag
    45301 caattagtaa tgccactaat atcagattcc atgaaaacca ccaccttaaa atataaaaaa
    45361 aagccctttt ccacttggga aaagggctct agattctaga acggtaccac cttttttcgc
    45421 ttaaaaaagc ttcttcattc acggacgctt tttgataaag ttatccgcta gcctgataat
    45481 ggaggcagcc acaatgatct acgttttcga cattgactcg gaaatgatgt tcgtctattc
    45541 gatttattgt catttctcac ttacatgact cactgggaat aaatcgttga atagcctact
    45601 gttttcctcg acgctttgct gtatgtttat ttgttgacgt aataatacac ctgttttttt
    45661 tgaaatgcaa gaatatttta actattttgt tttctttttt tgaaacaaga aaaataccta
    45721 gagaatacct ctgaatgaaa cggaatattt tgttctccac tttcatataa cttacattct
    45781 cagattcttt ttatcaaaac gagaccttta gcgaatggaa acagctattt tttaacgttt
    45841 cttggtacgt atggttaaac gactctttta caaccttttc ttatttgcta tatagtttct
    45901 tctgagtatg gtaaaatagg aaagaatgaa tcgaaaaaaa ggggatgtct atttttgacg
    45961 gaagagtcta gttctttaga gattagattg acagctgctg atgatgtcag catgctttta
    46021 ggtgcacacg acaagcatat aaaactgatc gaggaaacaa cggaaacaac catccataca
    46081 cgtggagaaa tcattcagat cattggtgaa caatcccaga tttccttggc tgcctcagtc
    46141 attcggacat tacaggaatt gatcaaacga ggaatccacg taagtacacc agatgtcgtg
    46201 acggcattga aaatggggca aaaaggtaca ttagattatt ttgttgagat gtatgaggaa
    46261 gagatcgtca aagaccgtaa tggaaaacct atacgggtaa aaaacagcgg tcaaaagaaa
    46321 tacgttgaat cggtagccaa acatgacatc gtatttggtg tagggccagc cggaacaggg
    46381 aaaacgtttc ttgccgtagt attagcaatt gctgccctaa aaaaaggcga agtgcaaaaa
    46441 atcattttga cgcggcccgc tgtagaggca ggggaaaacc taggctttct acccggggat
    46501 ctgaaagaaa aagtggatcc ttatctgcgg cctgtttatg atgctttata ccaaattttt
    46561 ggattggatc atacgaaccg attgatggaa cgaggcgtaa tcgaaatcgc accattagct
    46621 tacatgcggg ggcggacatt ggatgatgca ttcgttatct tggacgaagc acaaaacacg
    46681 acagtcgctc agatgaaaat gttcttgacc cgtctcggtt atcaatcaaa aatgattgtc
    46741 aatggggata caagtcagat agacttgcct cgagggacga caagtggtct tgttcatgca
    46801 gaacgaacac taaagcaaat caaaaaaatc gattttgtta attttgaagc aagtgacgtt
    46861 gttcggcacc ctgtagttgc cgaaatcatc aaagcttatg aaaaggcgga tcttcatcaa
    46921 gaataagctt tgcttaggag gataagcaca tgttgaataa aacactgcag aaactacaag
    46981 aaaaactcgg aaaggcagca ttgcctttcc ttctgttctt gttttttatc attgtctgcg
    47041 gcgttacatt tagtagtgtc aaacaaaagg ccaatgattt cagagaaggc caagtagcag
    47101 aagagagtat ccgtgcgaat aaaacgatcg agaacacgga agaaaccgaa caaagaagaa
    47161 aactggcagc agaagcagtg actccagaat atacttatca aaaagatctg gcagatgacc
    47221 agaacaatcg gatcaagcaa ttattcgaat tgatcgataa gacgaatgat accatcaaca
    47281 aatcttataa tgacaaggta gataaggcga aggaagatga aaatatcccg aaacctacta
    47341 cagaagagcg gattgctaca ctgaagaaaa attttgaaaa cgtgaatgca gaaaacgttg
    47401 cgttttacca aaaactgccg aacaattttt attcgacgat atttgaaatg actgaaacgg
    47461 aaattcacac ggttagggat gaaagtttga agctcattga cgaacagatg agtaaacaag
    47521 ttcgtgaaag cgaattggaa gcttttaaac aagaagcaga agatcagatt cagtatttga
    47581 atgtcacaac agagcagcaa caaatgattc gctacttagt ggatcaaggc attgtagtca
    47641 atgatgtatt gaatgagaaa aagacagaag aattaaaaca atctgcacga gaagctgtac
    47701 aaccagtgat gatcttccaa ggagaaatca ttgttcgcga aggaaatcaa attgatgctt
    47761 cagcgatgaa aaaattggaa ttactaggat tgacgaatca aacgacttcg attttcccac
    47821 tcattgccat ggttttagct gttttgcttc aaatcggcgt actgatttat aattcacttc
    47881 aattccaaaa tgcaggagaa agaacaaaat acgtgctttt ctatgtgaca gctatgtcag
    47941 tcagcatagt gctgatgaaa tttttccaat tattccaaac ggaacaagct acttatatcc
    48001 cgctgtttta tcccgctgct tttgcaccac ttgttttaag ctttttcttg aaccgaagag
    48061 cagggatcat ggctggtatt ttccaagcag tatctgcact tttcattttt tatgattcga
    48121 ttggcacgaa ctttctaacg attatcttga tgtcttatgt tttctctggg ctcatggcaa
    48181 cgattgtcag acgcaaacgg atctcagaac aaggattatc tgctgccatg tgggtcatta
    48241 tttttcctgt gatgatggat gtcattttga tcgtctatca aggaatgagc tttggtgatg
    48301 caacgacttg gttaatgctt gtctgcgggt tcactggtgc actcttctca ttcttgctga
    48361 cgatcggtct acacccatat attgaattga tggtcaatga tgacagtgta attgtattaa
    48421 atgaactcag caatccaaat catcctttat tgaaacagtt gctggaagaa gcgccaggta
    48481 cttatcatca tagtatgatg gtagctaatc taagtgctaa cgctgtagca gaaatcggcg
    48541 gacgttcttt gctaactcga gtagcttgct attatcatga tatcggcaag atcaaacatg
    48601 ctagcttttt cgttgagaac ttgccttcag gagcggaaaa cccgcacaat ttcttattgc
    48661 cagaagacag taaacatatt atctttggac atgtgacaga tggagccaaa atattggaag
    48721 attataatat gccgcaaatg gtgatcgata tttgcaaaca gcatcatgga accacgctaa
    48781 tgcgttattt ctacatcaaa gcgaaagaac gcaatccgga agtaacagaa gagcaattcc
    48841 gttatcctgg accaaaaccg caaagtcgtg aagcagggat cgtcaatatt gctgacagtt
    48901 gtgaggctgc agtacgggca atggatcatc cgacgagcga aaaaatcgaa agttttgtcc
    48961 ataatcttat cgaagagcgt atttccgatg gtcaattaga cgatagtgga ctgaccttga
    49021 aagaaatccg aaaagtggaa aaatcattga tcagcggttt aagtagcacc ttccattctc
    49081 ggatcaaata tcctaaaatg aaaacagaag ttgagaagat aaaggaagaa caagaagaat
    49141 agaaagaagc gatgtataat ggatattacc tttatggatg aaacaaacca agtctcagaa
    49201 gagaaaatga aagaaatcga tgacttgctg caatttgcag catcttattt aaagctgcca
    49261 gaggaaacag aaatgtctgt tactttcatg gacaatgcgg caatccaagt aatcaatcgt
    49321 gattaccgtg gaaaagatgc accgacagac gtcatcagtt ttgctctgga agaagaaggc
    49381 gaagacgaaa tcccagtgat ttttgaagat ggagagaatc ctttgcctcg tgtactagga
    49441 gacatcatga tttctattga acgtgctgct gaacaagcag aagcttacgg ccattcatat
    49501 gatcgggaac ttggcttttt agcggtacat ggattcttgc atatcaacgg gtatgaccat
    49561 atgacaccag aagatgagaa agaaatgttt ggtttacaga aagagatctt ggatgcctat
    49621 ggactcaaaa gataaaaacg tagagaaaaa caaacatttc ctgatgtctg tggaatttgc
    49681 tgtccaagga gtcaaaaccg tttttgagga agaacgcaat atgaggaaac atgttgcgtt
    49741 cggtatcctt gctttattta tgggcgtgat tttccagctt gatcggatag agtggttatg
    49801 gctgctttta gctgtttttc tcgtttggat agtagagatc atcaatactg tttttgaaaa
    49861 tgtagtggac atgtttacgg attttcattt tcatccgatt gggaaaaaaa tcaaagatat
    49921 ggcagctgga gcagttttag tgaccgcttg ttttgctgtc atcattgggt tgattttatt
    49981 tgtccctaaa atatatcatt tgttgtttaa ttaaaaagga gaacgtatat gccagaacat
    50041 aaatcagggt ttgtcgcaat cgtcggccgc ccgaatgtag gaaaatccac attattgaac
    50101 cgaatcgtgg gtcaaaaaat tgccattatg agtgacaagg cacagacaac tagaaataaa
    50161 atccaaggag tatatactac accagaagct cagctgattt ttatcgatac accaggaatc
    50221 cataaaccaa agcatcgtct aggagatttt atggtagaag cagcttacag tgcgttgaaa
    50281 gaagtggatg cagtcttatt tatgatcagt gctgatcaaa aacgcggccg gggagacgat
    50341 tttattattg aacgtctaaa aaacgtgcat tctccagttt atctgattat caataaaatc
    50401 gataagatcc atccagacga gttgctggga atcatcgaag attattcgac gcagatgcct
    50461 tttgcacaag tgattccgat ctctgctaca gaaggaaaca atgtcgaacg cttaatggat
    50521 gtattagtca gtgaaatgcc agagggccca caatattttc cagatgatca agtgactgat
    50581 catcctgaat actttatcgt ttctgaattg atccgtgaga aagtcttgtt tttaacacga
    50641 gacgaagtgc ctcattctgt cgcagtcgtt gttgattcga tgaagcgaaa cgagaatgat
    50701 aaaatccata tccaggccac gatcatcgtc gaaagagata gccaaaaagg aatcattatc
    50761 ggcaaaggcg gaaaaatgct gaagcaagta ggaacgaaag caagaaagga tatcgaaaat
    50821 cttttaggag acaaagtatt tctagaactt tgggtcaaag tccaaaaaga ctggcgagac
    50881 aaaaaagtct atctgcaaga ctttggctac cgaaaagacg aatactgata ttctgaactt
    50941 cttataggtt aagtatagaa ataaactgga taaaaatccg cacgttgaga aaaacggcgg
    51001 aagatcgaaa cataaataat ctggatcggc agaatctgct tttccagatt tattttttag
    51061 gagggagaat atgagccagc ttgcagaatc gaaaggcttg attttatcta gccgtaatta
    51121 caaagaaaaa gataaattag tcaaaatctt tacggaatct tctggcaaaa tgatgtttta
    51181 tatcaaagga atccatcggc aaaatcagcc attagctccg gctttgctcc cctttaccga
    51241 agcagtctat atcggtaatt ttcgaagtga aggtttgtcg tttttaagca gtgtcaaaga
    51301 cgtccatgcg tttcggaaca tccaagaaga tatctttttg agcggttatg gtacctattt
    51361 gctaaatcta gtagatgcag caatcgaaga tcatcaatat gacccgcatt tattccaatt
    51421 tacgcaacaa gctctgcagc ggatggatca aggagatgat gcagaaatca tcacgaatat
    51481 ctttgaagtt caaatactgc aacgcttcgg aatcgcgcca atttggacgc actgtgtcgt
    51541 atgcggggaa acaaaaggaa aatttgacta ttcttccaaa tctggcggtg tgatatgcga
    51601 gaaacactgg ccaatggacg aacaccgtta tcatgcagat cctcgcgctg tttatttcgt
    51661 tcgaatgttt tcggctattt cttatgataa gatcagtgga atccacttga aagaagaaac
    51721 gaagcaggca atccgtgacc tcattgacca gttgtatgat gaatatgtcg gtattcatct
    51781 aaaaagcaaa aagttcattg atcaaatgaa gtcttgggca cacgtattaa agacgccaga
    51841 gaaaaatatg cctgaaaaag agatacctga aaaagaagaa taaatgaaag atacaacaaa
    51901 aaaatcaaaa ctatttgaca aatacaggga cttccgtcta ttattaaccg tagattaaat
    51961 agatcgttca ctgagaggat ctattatata aacaagaaaa ctgcaaaatg aatacgtaca
    52021 ttgaccaaga tcagtaaaaa acacgtggtt tagcgagttc gggagagtgg aagccggacc
    52081 caaacgattt ttgaagaggc acttgcgagt acgataaatg aagctgccga atctttattc
    52141 ggaagtaggg tggaaccgcg aaattattcg tccctatgtc tgtaatcaga catagggact
    52201 ttttgtcgtt ttctttcctg tattcttatt gacagcaacg cttaaaaatt gaaaggggca
    52261 aaacagatga gtaaaaaatt gaccgtccaa gatatgattt taacattaca aaaattttgg
    52321 tcatcaaacg gctgcatgct gatgcaagct tatgacacag aaaaaggagc aggtacgatg
    52381 agcccatata cattcttacg ggcaatcgga ccggaaccat ggaatgctgc ttatgtagag
    52441 ccatcccgcc gaccagctga cgggcgttat ggagaaaacc caaaccgttt gtatcagcat
    52501 catcaatttc aagtcgtaat gaaaccttca cctgaaaata tccaagagct ttatttagaa
    52561 agcttgcgtc ttttaggaat tgatccatta gaacacgata ttcgttttgt tgaagacaac
    52621 tgggagaacc catcgatggg gtgtgccggt gtgggttggg aagtatggct tgatgggatg
    52681 gagatcacac aattcacgta cttccagcaa gtcggaggac taccttgtaa accagttact
    52741 tctgagatca cttatggact agaacgtctt gcttcatata ttcaagaagt tgaaagtgtc
    52801 tatgatctgg aatgggctga tggtgtgaaa tatggcgaga tcttcaaaca accagaatat
    52861 gaacattcca aatattcttt tgaagtaagt gaccaagact tgctactaag caactttgac
    52921 cgttttgaaa aagaagctaa acgctgtatc gatgaaaatc ttgttcatcc agcgtatgat
    52981 tatattttga aatgcagcca tacattcaat ttattagatg ctcgcggtgc agtatccgta
    53041 acagaacgag caggttatct ttcccgtatc cgcaacatgg ctcgtgctgt agccaaaatc
    53101 tttgtggcag aacgcgaaaa attaggattc cctttattga ataaaaacac agcaaatcca
    53161 gaaaacatga aggaggctga ataagatggc aaaagactta ttacttgaaa tcgggctgga
    53221 agaaatgcct gctcatgttg tcacaccaag catgaaacaa ttagaagaaa aaacagcaaa
    53281 atttttagat gaaaaccaat tgacttatga tacgatcgaa acgttttcta caccgcgccg
    53341 cttagcaatc aaagtaacaa acattccaga acgtcaagca gacagcgaag aagaagtcaa
    53401 aggaccagcc aaaaaaattg ctttggacgc agatggaaac tggacgaaag cagctgaagg
    53461 atttgtccgc ggacaaggtc tgacgacaga tgctatcact tttagagaat taaaaggcgt
    53521 ggaatatgtc tatgtaacga aatacactca cggcaaagaa gcaaaagaag tattgacagg
    53581 tttagcagat gtcattaaaa gcctcacttt cccagtaacg atgcactggg cagaatacga
    53641 ttttgaatat attcgcccta ttcactggat cgtggcattg ttagatgacg aaataatccc
    53701 gtttgagatc ttggatgtca aaacagacag agcttcaaga ggtcatcgtt tcttaggcga
    53761 agatgtgaca tttacgcatg caaaagaata cgaagaaaaa ttgaatgaac aatttgttat
    53821 tgcttcaccg caaaaaagaa aagaaatgat catcacacaa gcaaacgaat tagccgaaaa
    53881 aaatcactgg atcattgatc tagatgaaga tttactagaa gaagtcaaca atttagtcga
    53941 atatccaact gtcttttctg gcgacttcga agaaaaatat ctatctgttc ctgaagaagt
    54001 actagtcact tctatgaaag aacatcaacg ttatttcgaa gtacggaacg atcaaggtat
    54061 gttgcttcct cattttattt ctgctcgtaa tggcgatcgg gtaaaattgg aaaatgtggt
    54121 acgaggcaat caaaaagtat tgacggctcg tttagaagat gcggaattct tttataatga
    54181 agacaagaaa gcttcaatcg accaatacgt tgaaaaatta aaaactgtta ctttccatga
    54241 aaaaatcggt agcatctatg agaaaatgca acgggtacaa gtcatcgctc gcatcatagg
    54301 cgaacaagta ggactatctg aggaagaatt gatggatctg caacgcgctg ctgaaatcta
    54361 taaatttgat ctagtaacca acatggtagg agaattccct gaactacaag ggatcatggg
    54421 agaaaaatat gctctgctga aaggcgagaa accagccgta gcaacagcga tccgtgaaca
    54481 ttacatgcct atatccagtg aaggagattt acctgagact acagtaggtt ctgttttagc
    54541 gattgctgat aaattagata gtatcttttc tttctttgca gttgggatga tcccaagtgg
    54601 ctcaaacgat ccatatgctt tgcgccgtca agcatatggt gtcgttcgaa tcatcgaatc
    54661 gaaaaaatgg gcctttcctt tgtctgttct gcaagaaacg attagtgaag ttatcagtaa
    54721 agatacggat cgttttggca ttggcttgtc agcgggacaa caacaggtga tcgactttat
    54781 caaaggccgt ctgcgccaat tattgacaac gaagaatatc cgtcatgatg tcatcgaagc
    54841 tgttttgaat gcagaacaaa aagatctgac aaaagtattt gcagcagcac aattgttcaa
    54901 gcagcatctt gcagatgaag acttcaaacc atcgatggaa gctttgacac gtgtcgtgaa
    54961 cttagcgaaa aaagcggagc ttgaaaaaca atcagaagta gaccctgaac tgttcgaaaa
    55021 cgaagcggag aaagaactgc acaaagcagt agaggcaatg aaaacaagct ttgctgacca
    55081 aacgatcaac gaaaattatg atcagcttgt aagccttcgc ccactgatcg aaaattattt
    55141 tgatcagacg atggtcatgg cagaagaacc agcagtacgt aagaaccgat taacgcaatt
    55201 aagtcaaatt gctgccatgg ctttgtcact agcaagttta gatcaaatca tcacaaaata
    55261 atttctaata tgtaaataaa ccagagaaca ggcaca
//
LOCUS       DADVXV010000008        53815 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.008, whole genome shotgun sequence.
ACCESSION   DADVXV010000008 DADVXV010000000
VERSION     DADVXV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.008"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..1076
                     /locus_tag="KB969_000429"
     CDS             <1..1076
                     /locus_tag="KB969_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6868444.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
     gene            1429..2235
                     /gene="proB"
                     /locus_tag="KB969_000430"
     CDS             1429..2235
                     /gene="proB"
                     /locus_tag="KB969_000430"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBB6868445.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            2232..3479
                     /locus_tag="KB969_000431"
     CDS             2232..3479
                     /locus_tag="KB969_000431"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBB6868446.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            3555..3899
                     /locus_tag="KB969_000432"
     CDS             3555..3899
                     /locus_tag="KB969_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868447.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(4016..4342)
                     /locus_tag="KB969_000433"
     CDS             complement(4016..4342)
                     /locus_tag="KB969_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868448.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(4957..6159)
                     /locus_tag="KB969_000434"
     CDS             complement(4957..6159)
                     /locus_tag="KB969_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6868449.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            6276..6791
                     /locus_tag="KB969_000435"
     CDS             6276..6791
                     /locus_tag="KB969_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6868450.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(6990..7436)
                     /locus_tag="KB969_000436"
     CDS             complement(6990..7436)
                     /locus_tag="KB969_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6868451.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(7483..8961)
                     /gene="msr(C)"
                     /locus_tag="KB969_000437"
     CDS             complement(7483..8961)
                     /gene="msr(C)"
                     /locus_tag="KB969_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6868452.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(9315..9944)
                     /locus_tag="KB969_000438"
     CDS             complement(9315..9944)
                     /locus_tag="KB969_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBB6868453.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(9928..10392)
                     /locus_tag="KB969_000439"
     CDS             complement(9928..10392)
                     /locus_tag="KB969_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6868454.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(10879..12147)
                     /locus_tag="KB969_000440"
     CDS             complement(10879..12147)
                     /locus_tag="KB969_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6868455.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(12378..13115)
                     /locus_tag="KB969_000441"
     CDS             complement(12378..13115)
                     /locus_tag="KB969_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6868456.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(13182..13751)
                     /locus_tag="KB969_000442"
     CDS             complement(13182..13751)
                     /locus_tag="KB969_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBB6868457.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            13879..14751
                     /locus_tag="KB969_000443"
     CDS             13879..14751
                     /locus_tag="KB969_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6868458.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            15093..15965
                     /locus_tag="KB969_000444"
     CDS             15093..15965
                     /locus_tag="KB969_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6868459.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            15962..17920
                     /locus_tag="KB969_000445"
     CDS             15962..17920
                     /locus_tag="KB969_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6868460.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(18252..19103)
                     /locus_tag="KB969_000446"
     CDS             complement(18252..19103)
                     /locus_tag="KB969_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6868461.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            19226..19693
                     /locus_tag="KB969_000447"
     CDS             19226..19693
                     /locus_tag="KB969_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBB6868462.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(19956..20438)
                     /locus_tag="KB969_000448"
     CDS             complement(19956..20438)
                     /locus_tag="KB969_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBB6868463.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(20538..21401)
                     /locus_tag="KB969_000449"
     CDS             complement(20538..21401)
                     /locus_tag="KB969_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6868464.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            21999..22874
                     /locus_tag="KB969_000450"
     CDS             21999..22874
                     /locus_tag="KB969_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868465.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(23019..23171)
                     /locus_tag="KB969_000451"
                     /pseudo
     CDS             complement(23019..23171)
                     /locus_tag="KB969_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(23439..24770)
                     /locus_tag="KB969_000452"
     CDS             complement(23439..24770)
                     /locus_tag="KB969_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6868466.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(24919..25632)
                     /locus_tag="KB969_000453"
     CDS             complement(24919..25632)
                     /locus_tag="KB969_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6868467.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            25807..27231
                     /locus_tag="KB969_000454"
     CDS             25807..27231
                     /locus_tag="KB969_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6868468.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            27530..28237
                     /locus_tag="KB969_000455"
     CDS             27530..28237
                     /locus_tag="KB969_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6868469.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            28224..28547
                     /locus_tag="KB969_000456"
     CDS             28224..28547
                     /locus_tag="KB969_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6868470.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(28636..29673)
                     /locus_tag="KB969_000457"
     CDS             complement(28636..29673)
                     /locus_tag="KB969_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6868471.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(29994..30977)
                     /locus_tag="KB969_000458"
     CDS             complement(29994..30977)
                     /locus_tag="KB969_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBB6868472.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(31392..32162)
                     /locus_tag="KB969_000459"
     CDS             complement(31392..32162)
                     /locus_tag="KB969_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868473.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(32155..33090)
                     /locus_tag="KB969_000460"
     CDS             complement(32155..33090)
                     /locus_tag="KB969_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868474.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(33406..35055)
                     /locus_tag="KB969_000461"
     CDS             complement(33406..35055)
                     /locus_tag="KB969_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6868475.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(35172..37775)
                     /locus_tag="KB969_000462"
     CDS             complement(35172..37775)
                     /locus_tag="KB969_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBB6868476.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(37787..38836)
                     /locus_tag="KB969_000463"
     CDS             complement(37787..38836)
                     /locus_tag="KB969_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBB6868477.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(38862..39176)
                     /locus_tag="KB969_000464"
     CDS             complement(38862..39176)
                     /locus_tag="KB969_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBB6868478.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(39192..39638)
                     /locus_tag="KB969_000465"
     CDS             complement(39192..39638)
                     /locus_tag="KB969_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6868479.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(39639..41561)
                     /locus_tag="KB969_000466"
     CDS             complement(39639..41561)
                     /locus_tag="KB969_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBB6868480.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(41773..42669)
                     /locus_tag="KB969_000467"
     CDS             complement(41773..42669)
                     /locus_tag="KB969_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6868481.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(42662..43342)
                     /locus_tag="KB969_000468"
     CDS             complement(42662..43342)
                     /locus_tag="KB969_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6868482.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(43343..44125)
                     /locus_tag="KB969_000469"
     CDS             complement(43343..44125)
                     /locus_tag="KB969_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868483.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(44118..45035)
                     /locus_tag="KB969_000470"
     CDS             complement(44118..45035)
                     /locus_tag="KB969_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6868484.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(45199..45522)
                     /locus_tag="KB969_000471"
     CDS             complement(45199..45522)
                     /locus_tag="KB969_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868485.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            46310..49537
                     /gene="fss3"
                     /locus_tag="KB969_000472"
     CDS             46310..49537
                     /gene="fss3"
                     /locus_tag="KB969_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBB6868486.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            49650..49964
                     /locus_tag="KB969_000473"
     CDS             49650..49964
                     /locus_tag="KB969_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6868487.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            49977..50351
                     /locus_tag="KB969_000474"
     CDS             49977..50351
                     /locus_tag="KB969_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6868488.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            50361..50696
                     /locus_tag="KB969_000475"
     CDS             50361..50696
                     /locus_tag="KB969_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBB6868489.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            50779..52119
                     /locus_tag="KB969_000476"
     CDS             50779..52119
                     /locus_tag="KB969_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6868490.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            52197..52871
                     /locus_tag="KB969_000477"
     CDS             52197..52871
                     /locus_tag="KB969_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6868491.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            52864..53028
                     /locus_tag="KB969_000478"
     CDS             52864..53028
                     /locus_tag="KB969_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868492.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            53104..53538
                     /gene="dcm"
                     /locus_tag="KB969_000479"
     CDS             53104..53538
                     /gene="dcm"
                     /locus_tag="KB969_000479"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBB6868493.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQRFSDTRGTLFFEIARF
                     TTLLRPKLLFLENVRGLLNHEGGATFETILRTLDGLGYDVEW"
     gene            53539..>53815
                     /locus_tag="KB969_000480"
     CDS             53539..>53815
                     /locus_tag="KB969_000480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HBB6868494.1"
                     /translation="MLNSKAYIPQSRERIFLIGHSRDACTEQVFPIIGPSSTSDQNIR
                     NLVNINPSNRGMGGQVYGSDGVAPTLTGDEGIKIALPARDGISVAGLL"
BASE COUNT        16566 a        10689 c         9638 g        16922 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttgactta
     1201 tcaccattag actaaataaa ctactcctat tctaacatat ccgaggctgt aaaagacttt
     1261 ctttacaaat tcttcaagaa attctgctat cttaaagtaa accattaatt cgttcttttt
     1321 ccaaacgact gcaagttgta caaaaaaact attttttaca tgactttact cgtcaaaaca
     1381 agtagaatag aacgaaatta atgagtggat atttgattga ggtgtcacat gcgtaaagaa
     1441 attaaaaatg caaaacgaat tattgtcaaa gtaggaacaa gtacattgat ttatcccaat
     1501 ggaaatatca atcttgcggc aatcgatcag ttagcttttg tcctttctga tcttagaaat
     1561 cggggaaagg aagtgatctt agtctcatca ggagctgtag gcgttggtat gcataaatta
     1621 catttgtcag aacgtccgac tttgattcct gaacagcaag ctgcggcggc tgttggtcaa
     1681 gccgaactga tgaatatcta taatcaaaga ttcagtgtat ataatcaaca gacggcacag
     1741 atcctcgtga caagagacgt ggtagattat cctgaaagtc gtaaaaatgt gaggaataca
     1801 ttggaacagc ttttgattat ggacacgatc cctatcgtga acgaaaacga tactgtagca
     1861 gtggatgaat tagatcatct gacaaaattt ggcgataatg atcagctgtc agccatcatg
     1921 gcaaaacttg tcgcggcaga ccttttgatc gtcctttctg atatcgacgg gttttattca
     1981 gataatccga ctacaaatcc cgaggctcag atgtatcgct atatcgataa aatcgatgaa
     2041 aagattctgg cacaagcagg tggtgctggt agcacatttg gaacaggcgg tatgcagagt
     2101 aaattaaaag ccgcttctag gatatttgaa gcaaacagcg caatgatttt agcaaatgga
     2161 aaaaatccgg caattatttt tgatattctt gcaggaaaag aagtaggtac tttatttaag
     2221 gaggacttga aatgactgac ttgatgcaat taggacaaca ggcaaaagat agcgcgcaac
     2281 aactagcact tatgcctaca aaccgcaaaa atgagctact tgttcaaatg gcacaaacca
     2341 tcaaaaagaa tcaacaagcg atcattgaag caaatcataa agacttagaa aaagcagtcg
     2401 aaaacaatat cagtgaaacg atgcaagacc gcttgcagct gacacctgag cgaatcaatg
     2461 ccatggctac agagatcgaa aaaattgctt cgttagacga tcctattgga aaagtagatg
     2521 agatgtggac gaacaccgac ggattgagaa tcggcaaaaa gcgcgtgcca ctaggcgtga
     2581 tcggcatcat ttacgaatct cgtccaaatg tcacgacaga tgcagctagt ctagcattca
     2641 aatcagggaa tgccgttatc cttcgcggtg gcaaagaagc attcttctcg aatcaattat
     2701 tagtccaatt attgcagcaa gtactggtca gtgctggcga atctccttat gccatccagt
     2761 ttgtcgatga tacttctcat gaaactgcag gacagttgat gcgattgaca gaatacttag
     2821 atgtgctgat tcctcgaggc ggagcaaaat taatccaacg agtcaaagaa caggcaacgg
     2881 tacctatcat tgaaacaggt acaggaaata atcacgtata tatcgataaa gaagcacagt
     2941 tatctatggc agtgaacatc atcgtcaatg caaaagcttc ccgtccatct gtctgtaacg
     3001 cggcagaaac attgctgatc cattctgaga tcgcaccttt tttcttgcca gctattgaaa
     3061 aagaactggt agaacacggg gtctctttac gtgcggatgc tcgtgcgtta gaatatctag
     3121 agacggctgc tttagcagaa gacacagatt gggatactga atatctagat tatatccttg
     3181 ctgtcaaagt ggtcgattct ttggatgaag caattgcaca tatcaatcgg cataatacta
     3241 aacattcaga aacgatcgtg acagatagtt atgcggctag tcaacgtttc ttaaatgaag
     3301 tggacgcggc ggctgtctat gtcaatgcct ccactcgttt tacagacgga tcggtatttg
     3361 gttttggtgc agagattggt atctctactc aaaagttgca tgcccgtggt ccaatggggt
     3421 taaatgaatt aacttccaca aaatatatca tttatggcga tggacaaatc cgcgaataat
     3481 gtttcgtgtg aaacattatt cccgcctttt gccttttttc tgtaaaggtt ctatccaact
     3541 agaaaggtgt caatatgttt gaaattttaa tgattttttt tatttacctt atttctctga
     3601 atatcgctgc ttttctggga gtcggtattt tatccctttt ctttcaattc aaaaaacgaa
     3661 gcatagggag tcaacgggaa aaatggtcgc agtattttga caaaatcggg caaaaagggc
     3721 tggttacacg cttgcacatt agttacatgg ttgcattatg cttattagcg acaatcaatt
     3781 actattcttt tttcgatcat tcaatcgctt atacgattac gctactgatt gctgggattt
     3841 ttcacttatc ttataaatat cagctgaata aaaaccactt gaatcggact ttccgctaaa
     3901 aaatatccgt acgataagta gagtgccttg aagatcggca aaaaactgcc ggacttttta
     3961 gaggctgtga caaagatttt gtcacagcct ctttttccat ataaacggcg ttcgcctacc
     4021 agctgcctgg taaatctgtt tcctcttcgt taagaagcga aaatccgtca aatgtttcgc
     4081 catcataata acgaagcagc tcatccatgg acaagttcat cgttttttct ttttcttctt
     4141 ccgctgattc agccagtagc tgttcccgat acacctgata cataccagct attttttgct
     4201 gcatcgcttt tctagtttca ccttccgcat tgattattgg caattctttg atatagccac
     4261 gataaatcaa ccgatcatct gaaaattcaa tgggtaattc aacgagtgtc aacccgactt
     4321 cctgaaaata ttcttccagc atctattatc cccccattct ttttcttaaa tgaattttag
     4381 cttacctact gaaaattttc cagtttcatt attttgagaa aaaaagggaa tgtgacaaaa
     4441 atcgtgtcac atcccctttt tccgaataaa tggtgttctt ctgccaactc ctcaatcata
     4501 agtcacaata ttcaacaaac atgagaaact gttttttgaa attgttcctt gtgattcaga
     4561 gttaaacgac agtctcacaa cctcttggta aacggcgttc aatcagctga ccctcggtat
     4621 tagctcaaaa aacggtaaaa tatgagaagc tatttttccg ttttgtttct ctaatactta
     4681 ggataaaacg ctgattttac aacctctgtt aaacggtgtt caatcagctg tccttcggta
     4741 ttagctcaaa aaacggcaaa atatgaggaa ctatttttcc gtttgtttct ctaatactca
     4801 ggacaaaacg ctgattttac aacctcctga taaacggtgt tcaaaagctt gcatctgcgg
     4861 taataagccc aaccaaacga aaaatatgag aagctatttt tgtttggctg ttcttatgac
     4921 ttgatgcagg acagcttttt cacaacctct gatttcttat tcttcttcat ttgtagcaaa
     4981 ataattacgg tgataaatga tacaacatac actgataaga acaatggcac ctgcaaaata
     5041 aaacgcatag ctttcaccaa tatgttcacc aatcacacct gcaataaatg gtgctaaagc
     5101 tccaccgaaa aagcggacaa aactatagct ggacgaagca acgtttcgtt gcagacctgg
     5161 tatttccata gcaatcgtcg tcaacagtgt attgataatt ccttggaaaa atcctgctaa
     5221 cacaatgctg atcggtacaa ggactggcat agaagttcca gctcctaata acagcaaaca
     5281 aataatgaat aagacaaatg ctgctaaaat tgtccgataa gtcgtaaact tccgctcaag
     5341 agccggtgca acgaaaatcg aagcaatagc cagaagcaca ccccagccaa aaaatacaaa
     5401 accgacttct aattcagaat agccaatcaa taaaaatggc gcatacgcaa gtaaagtaaa
     5461 gaatccgaaa ttatataaca atgcgattag tccaactgaa cgaagtttat gattgcttaa
     5521 cgctttgaca ccttcccaaa ggcctacttt tctctttggt ttctcagttt caggtaaaag
     5581 taccgctagg gctataaaac cgcaaaacat caaaaatgct accccaaaaa atggataacg
     5641 ccatgaacca ctgcccaaga ccccaccgac tagagggcca acagccattc cgcagccaag
     5701 tgctgcttca tacatcatga ttgctttttc tgtgttacca actaaaatac tgacgatcgt
     5761 tgctaaagca gtagagacaa ataaagcatt cccgacaccc cagccggcac gtaacccaat
     5821 cagcattccg atattcccag ataatccgcc aagaccagcg aatacaacga tgataaacaa
     5881 tcctgtcatc aatgtttttt tcaaaccgat ccgactagat aagaaacctg taaatagcat
     5941 caccacacca gtgactaaca tgtaactagt aaataacagg gtcgtttcag ctggcgtagc
     6001 gtttaactgt gcagcaatcg tttttaagat tgggtctact agacccactc ccataaaagc
     6061 gatcatacag gtagctgcta caactagcgc tgaacttttc ccctttgttt cttcatttgt
     6121 ttgttcttgt atatctattt gattctccaa tatttccatc cctttctctc tattagcatc
     6181 atacatgatt tattttacat gtcaatatgc acatgtaaaa cgtggaaact ttactgtgat
     6241 ataataaaga aaataagacg agaggtagga tttttatgaa tactttagcc tatatattat
     6301 tatgcgtgct tttatccaaa ccacgttctg ggtatgaatt gaagcagctg atcacaattt
     6361 tttgggaagc ccatcacagt cagatctata caacgcttgc caagttagac cagcagggtt
     6421 atgtgaccgt tttggacaaa gacgagcact ctcaaaaaaa gatctaccac ttgactgatg
     6481 aaggacgtgc tcttgtagag gaatggatca aagaggaaac tcccgctcct acgcaaaaag
     6541 atgaatttct agcaaaaatc tatgcttttt cgacgctcga taaaacaaca gctactggac
     6601 tgctattcac tagagaacaa cagctgaaca aaatcatgca aaaaaatcaa aaaaaattga
     6661 atgacctctc gctagacaag aaacaagaat ttggacgtta tgttgtgatc cagcgcagaa
     6721 ttatgctttg tcagcaggaa ctccaatggt gtcagcaagt aagagaacaa atgcagcagt
     6781 tttttgagta agggataaac agaacctttc tagaaatatc tattgaagag caaattatct
     6841 tcaataaaag agcaatacag ttggaaaaga aaaagcgatc cgaacgacag gccaaaacct
     6901 atcgttcgga tcactatttt tctagaactg cattcaagag actatgacaa aaagcatgcc
     6961 aaggcctttt ttcaaataac agtgttccat cattcattac tttgaattgc ttttagcaca
     7021 cttcttgaaa gcgggccaac gatgatcaac tgcaacggta aagcggcaat cacattcatt
     7081 ttccaagcat tcatataagc agagaataat tgatcaggta ttccttgttc catgatcaca
     7141 ccgaataaag acatacatgt caccattcct aaaaccatca agcatgaaat agttaagatc
     7201 atttggacct tgctttctgg atttactggt agtttaaagg caattttttt cgccagcaca
     7261 ccgatgatga agacatccaa aatgaaagcc accacgaatc caggcactag accaatcaac
     7321 aaacttgata aatgaagatc ttgatgcagc cataaattat acgcgctcat ccccaagacc
     7381 atcaaaaaac acatcattgt tgtaaaaatt attccttctt ttttatttgt aggcaatctg
     7441 taccactcct ttaaatttgt cacgaaaatc atcgtagcac atttaaaaat ttctcgtaag
     7501 tacttttttt attttctgcc cttttatttc ataaacttca tcagccgtac gctcgacaaa
     7561 gtaagaatca tgagaagtaa acaaaatcgt tcccggatat atttgcatta gcttctctaa
     7621 agcttcgatc gttgccatat caataaaatt agtcggttca tctaacagca acacattact
     7681 tggcttagta aaaagcaaag caatcgtcag acgggtcgct tctcccccac ttaatgtaca
     7741 taacggtttc gtcaaagttt cctgagcaaa ccctaagtga ttcagcaaac tacggacaag
     7801 cgattctgaa aactctgttt gtctcatgac aaaacgaatg atggattctt cagatgtcat
     7861 ttgataaccc ttttgctgat atacttgaaa gcttactttc ggagagagaa ggattccttc
     7921 tccttgtttg cggatatgtt ctaataaggt tgtcttacct gaaccatttt caccgacaat
     7981 cgcgattttt ttacctaaag aaaactgaaa atcaccattt accagtaatg ttctcccact
     8041 tctttccaat tggacatttt gtcccatgat gggatagcgg ctgtggagtt caagagattt
     8101 tggtactgga aaacggattt gtttcatctg ctgcggcttg gttgtttctc ctattttttg
     8161 gagtcttctc tctaatgttt tcgcattctt ttggatggct ttttgtacac tgtctttttg
     8221 tttagaggaa gacaaccgat ccagtctgat ttgttgcttt ttctttttac tggacacttt
     8281 ttccaacttt tccgcttgtt ttttcttttc ttggatcgat ttttccaatc gttttttctc
     8341 tttcatgatc gactctgctt ctcgtagctg agtctttttc tccaattcct tttgagtgag
     8401 ataggcacta taattccccg aaaactctcg gatttctccg tcttttactt cccagatttt
     8461 cgatgctagc tcatctagaa aatagcgatc atgactaaca aaaaccagcg taccataata
     8521 ataacgaagc tcttcaatca gtcgatcaat actttttcta tctagatggg ttgttggctc
     8581 gtctagaagc atcccttgtt cataagaaga aagaagacgt atcaactcga tctttcgttc
     8641 ttcccctccg ctccatttcc gctctgaagt ttcttccagt cttaactgga aatgactggc
     8701 taattccaaa tttaggtcct ttgcttcagc gagataggtt aattgaggca ggtagttgaa
     8761 ggtgatctct gtttggattt tcccatgatc gggaaaaagt tcaccggcta ttagtttgag
     8821 caaagtcgat ttaccgacac cattttctcc tatgatccct atacgatctt gctgatagac
     8881 acgaagagaa tcaatagata gttctagctg gttgccaaag ctgacttgta gatttgttat
     8941 atttactgct aaattttcca tatgttttac actcctattt catgtaaaac aacaattatc
     9001 gatactaaaa aagagcagaa aaatctgttt gcaaaaaaac tgcatcacat cttttcctac
     9061 tctgaacgaa ataactatga ctaaatcacc aaatctgtca tagctttcac ctattctact
     9121 gtcgttcgaa aaaatggaca tactccatcc atgaaattgt tgtttataca tgtcttttga
     9181 atttatttag ttgttattca aaagttcgaa acgtaatttc atcgatgcag tcatttttcc
     9241 gacctccttt tttattaggt taccacacac gattcaaaaa aagcaatagc tactgaatag
     9301 taactgaaaa ccttttattc gaacatagtg atcttttctg gtgctaaacg aacagactcg
     9361 taaccttctt ctaccgcttt tcctattgat aaaataataa ctggaacata acggtcttta
     9421 tccaaaccaa atgcctctgc caactgatct gcttcgaatc caccaattgg atttgtttca
     9481 tagccatgat cacgcgcaac taacatgaat tgcatagccg ctaagctaga atcgactttg
     9541 actacatcgt tcatttcttc tcttgaaaaa ctcttgtaat aaggaatgat cgcagctaat
     9601 tgttgatctc tgacttcttt tggcatcttc cctgattcgt aagcttggtt gtagatttct
     9661 tcgccatatt cgtaacattg catatcgcca aaaatcatga ccattgcaga agaagtatca
     9721 ttttgtctcg tattgaaacg gatcaaagga cgcaagattt cttttgcttc ctcgctttca
     9781 gcgaccacaa agcgccatgg tttcatattg acagaagaag gtgcagtcgt cgcttctttg
     9841 atcatttcca gcatttcttc gtgtgggatt ttgtatgttt catcatatac gcgaacggat
     9901 cttctaccag tcataattgt tgaaaaatca tttttttgtt ccattattat taacctcttt
     9961 cgtttctgtt gttatattgc aaagttgggt attcaattta tctaaaagtg ttagaaattg
    10021 tttcatttct acatcgctga aagccgggga tagcacggaa cctgtatctt tatggtccat
    10081 ttcacaatgc ttgattttct tctgggcttt ttctgttagc gctacataca cttcccggtt
    10141 gttctgagga tttctctgac gcgaaacata gccatttgct tccaatacct tcagatgacg
    10201 agtaactgct ccttgatcaa tctgcaactt ttcttgcaaa ctgctttgta gcaatggatt
    10261 ttcttctttc agtctcatca tgatctcgta tctagtaaga cttataccga tattttcttc
    10321 aaagatctgg acgatttttt gatcggctaa tttgatttga tataaaaggt gactaatctc
    10381 ttctaaagac ataatttcct cctttctaat aattgactcg tcaacgattg acttgtcaat
    10441 aatagaataa aaaaagaaaa aagtcaaaga atcagctgtg taataaaaaa aacgctctca
    10501 atagaaaagt atagagaaaa gaaatttttt gtagaatgaa cggaaaaaat gataaagaaa
    10561 gcacaacgct aaaaccaaga ttattgattc ttatcaaact atagaagata gctcttctgc
    10621 agtagataat tttacaccgc caaaaatttc cgaaatcgcc ttttgcaaga atcccgtcga
    10681 atattagaaa ttggatcagt atgcttaaac agtaataaaa aagttatgac aagatgttgt
    10741 cacaaccttt tttgagtaaa cggtgttcaa aaacttgcat ctgcggtaat aagttcaacc
    10801 aaacaaaaaa catgaaaatc tgtttttgtt tggctgttct tactacttga tgcagggcag
    10861 ctttttcact acctcttttt aataaccata aaatcctatt ccttcatatc tccagcccat
    10921 cggtgttagc caatctcttt ccttagcact caaggtatag tgatgggtac cagttttttc
    10981 atttggatta aatagtcgat aaattggctt ggaaccacca gaataaaaac ttagaccttc
    11041 ataacgccaa ccgatttttg ttaaagagtt gatctcagat tgtgccattg tgtaatgatg
    11101 gtctccactg taaggattgt ataaacggta gacaggttgt ccgctgtttg gtgcttgcca
    11161 agcaatccct tcatattccc agcctacagt tggcagataa tttttttctc cggcattcaa
    11221 tgtatataaa tgttctcctg tatgacggtt atacagacga tacatcggag aagttgaagt
    11281 tggtgctgta tcatactgtg tcagattata ggtttcgatt acattgttca atgtagaacc
    11341 ataattaggc gcagtggcat aacgacctgt tagccaagcc gtagcatctt tgtaagagtt
    11401 cgtattgctt ttccatgcac cggaatagta gtaaacgcct ggctgaaaag aagtcgtctt
    11461 caataccgtt acgttatctt gcaatgattc tttgtacgaa ggatattttc taaaagcggc
    11521 attcaccgta atccattgcc cattcacata ttccgaagta ggcatcgtaa cagattggcc
    11581 attatagctt cctttaatcc caaatagatt gtaattaggg gcagaagcca aagtactgtt
    11641 cccccagcca ctttcaacga tggcttgagc aatcatgact gatgcatata agtcattggc
    11701 acttgccaaa ctttgtgcag ttgaggcaat actatcaatg aacgcttgtt gagaattagc
    11761 agatgagcga gcataaaaag catagccagt atagttttcg aattcagaca aatctgcttg
    11821 atgggtatgt gtcaatgttt gcccatctgt caattggttc gtgatttctt ctgcattctc
    11881 tggattgttc tgagcttctg ctgatgtact gtcttcggtt tgtgtttgtt ctgttgtttc
    11941 agttgttggt tcttcggttg aaattgtatt ttctgagaca gtagctgact gcaaagtact
    12001 ttctgtatcg ttttcaattc ctgtttctga agaactcgat gtctgagttg cgacagtttc
    12061 tgtcgattct tcagctagca ctgttgtgtt ggcaactgct agatttccta aaagaataac
    12121 gctaaataat aaattctttg ctttcatctt ttttctcctt tgaattatga aacttttcct
    12181 aaataacagt gtaactaaaa aagtaaaagc aagtcaatgt ccatatttaa ataacatttg
    12241 tttcttttta ataaatttgc tttttctgca taaaaagacg taaatgaaga atattcttct
    12301 ccattcacgc cttaaattga tggtcgtttg aataactatt taacaagtaa ttctctctgg
    12361 atattatccg ttatggatta tacttcctgt gtcgtcggac ggataatcat gttgctgaca
    12421 gacatccggt ctggcgtttc tatcgcaaat gctacagcag aagctatatc ttcagatgtt
    12481 aatccccatt ctttttgcgc ttcatgaagt tcaagagcag cctttttgtc gctgatggtt
    12541 tgatataatt cagtttgaac agctcctgga gagatgatcg tagatttgat gttattttgc
    12601 cgttgctctt gacgtaatcc ttccatgatt gcacggacag caaattttgt tccgcaataa
    12661 acggcggaat caggataaac aacatgtccc gccacagaat cagttgaaat gatatgccca
    12721 gatttttgtt tttccatgat tggaagtacg gcggaaattc catttaacac acccatgatg
    12781 ttgatatcaa gcatattttg ccattcatca cggtgacctt caactaatgg agcggttggc
    12841 atgattcctg cattattgta caatacatcg attcgaccga acttttccat cgctaaatcg
    12901 ataactgctt ggacttgtgc aaaatctctt acatctgctg tttgaatata tagctcagct
    12961 tctggtaaag attcttttat tgcttttagg cgatcttctc ggcgtgcagc tataactagt
    13021 ttagcccctt tttctgctaa tagcttcgtt gttgcttcac cgattccgct tgaagcgccc
    13081 atgatgacaa tcactttttc tgataaatca ttcattctat tctcctcctg ttttgaaaaa
    13141 tctcttgctt atactcacta tctcttattt catcttactg ttcaaataat ccgttcgaca
    13201 ggtttgacga ttttggcagg gattcctgca acgatggtat tgtctgggac atctttcgta
    13261 acagttgcat tcgctgcaac aatggcattc tcgccaatcg ttacgcctgg cagaatagtt
    13321 gctcctgctc cgatccaagc atttttcttg atgtggattg gctttactga caagcctctt
    13381 cgttcttttg gatcggttag atggttcacc gtgatgaggt tgacacgagg accaatcaat
    13441 actgaatctt ctaaacagat gccacctaag tcaacgaaca tcacttgacg attgataaag
    13501 acatttttcc ctatactaat atgtttgccg aaatctgtat aaaaaggcag cagaacagtc
    13561 accgtatcat ctactttgtc actaatgata ttttctagcc gtttgcggat atctgctggt
    13621 tcatggtacc cagtattcag cgctgctaaa ggctcttcgt tttccgcttg gatctgatgg
    13681 atcacttcaa agagcggatc cgttactcga atctctttat tgacgatttg tttttcgatg
    13741 aggcttgtca ttttgctccc tccttttatc cttactttat aacggacggc ttatgatgtc
    13801 taatacttat aaaacatact taactattcc ttttaactat acttagtggt atgctttttt
    13861 aaaaacagga gggaaaaaat ggatattcgt atactgacgt attttttagc agtagctaga
    13921 gaaaaaaata tcagccgagc agcaaaatct ctgcatatca cgcaacctac tctctcaaaa
    13981 caactgaaag atttagaaga agaacttggt gtgacacttt tcactcgagg ctcccgagag
    14041 atacagttga cggattctgg tcgatatctt tattcaaaag gaaaagaaat cttgtcgttg
    14101 gtagaaaaaa cggcgaacaa tttaacaaat gacgcaatca tctctggaga aatctacatt
    14161 ggcggaggcg aaactaaagc aatctctttc atttctgata gccttcattc gttgatcaag
    14221 gcgcatcctg atatccagtt tcatttatat agcgggaatg cagatgatat catagacaaa
    14281 ctggatagcg gattacttga ttttggactc gtaatcgaac cgacaaacaa acaaaaatac
    14341 cagtcatttc gactgccagc ccaagatcgt tggggacttt tgatacatcg gaatcatcct
    14401 ttagcaaagc aaacagtcat ccatccgcag gaactgaaaa ctgttccttt gatcatttcc
    14461 cggcaaacgt cagtggacag tcaactagct gaatggctag gtttcagcat agatcagtta
    14521 tcgatcgtcg gaacatataa cttattgtac aatgcttctt tgatggtcga taacgggact
    14581 tttggtgcat tagctctaga tgggatcatc aatacttatg ggacggaaaa agtattcatc
    14641 ccactcgatc cgccattaca agcttcactg aatctcattt ggaaaaaaga ccagcctctt
    14701 tctcctgctg ctcgtaaatt tttagatgtc ctaacggaga aatacagtta agtagagttt
    14761 ttttccttcg ctttcagctt tttaacaacg aataagttaa gcaaaagatc caatgattaa
    14821 ataacataag tttcttaatt tgttccttcc ttttatttct gataattcca gtaaattact
    14881 ataattataa aaaaagaatt gacaaaacat aactgtctat ataaaattga ttacgttaac
    14941 aataattcgt ttcatgtgac tagatcatac taggcatgaa aaatctctga ggaacatggt
    15001 ttccctagga ggtttttcgt gtctattttt gtttggccgc aatcaactgg tctagcaaac
    15061 gtgaaaacca aatcttcaaa aagggtgcgc gcatgaaaat caaaaagatc tttaatcaaa
    15121 atgcagtatt ggtagatgac ggtggacagg aaaaagtagc tattggaaaa gggattggat
    15181 ttgacagaaa aagaaatgat ttgatttttg atcgtgatgt cgaacggata tttgtcatgg
    15241 aaccagaagg tcaaatcaag ttgcaaaatt tacttaatca gattgatgaa cgctttttat
    15301 ttgcagcaga aacgatcatt gatcatgcgg aaactgtttt gatggaaaag ttgaatgaac
    15361 atgtattgat cgctttgacc gaccacattg ctttttctgc ggagaacatt aataacggta
    15421 tcgtcatccg caacaaactt ttaagagaaa tcgaagtgct ttacagtgat gaattcagta
    15481 ttgctcaatg ggcagtagag tatctgacaa aagagcttgg gattccatat acttatgacg
    15541 aagcaggata tatcgcaatc catattcaca gcggacgaag cggtcggaac aataaccatc
    15601 gcagtatccg tgaagtgacg attgtatctg acatcatcca tttagtggaa tcagaattgg
    15661 aaacagatat ccattcagaa ccattttcac tgaattattc aagactggtg aatcatttac
    15721 gactgcttct acaacgaacc catgcgcaac aatatgctgt tttagacacg gaaatcgtag
    15781 aaatggtcaa acgaaaatac ccagaaagct ataagatttc taaaaaaatc cgtgtgttgc
    15841 tgaccaaaga ataccagctc gcgatcacga aagaagaact gggttacttg gccatccata
    15901 tcgagcgttt aagaagcgca atcgtacaaa caaatgttaa caatcatgag gaggaaaaaa
    15961 attgaaagca tatctacaac gaatgggacg ttcccttcaa cttccagttg cggtcttacc
    16021 tgctgctgct ttactagtag ggatcggaaa ctggtgggca tcttatagta acgacattgt
    16081 cgctcatttt ttacaagctg gcggtaacgc agttttaggt caattacctt tgctgtttgc
    16141 cgttgggtta gcactaggga tgtcagtgga caaatcaggt gctgctgcct tggcaggttt
    16201 ggtcgcattt gaagttccag taaatgtttt aaaaactgat tcagtagcta ctttattgaa
    16261 tatcaaacca gaatcagttg atccatcttt tgctcagatc agtaacgtat ttattggtat
    16321 tattgccgga ttgattgcgg cagctcttta taatcgtttc cacgaagcaa aattaccgat
    16381 ggctttatct ttctttagcg gcaagcgtct agtgccaatc ttggctgcct ttgtcatgtt
    16441 gctgatcagt gcagtgctac tgctcgtatg gcctccggtt tactctgctt tagtttcttt
    16501 tgctaaattc attttgagtt taggctgggg tggtgcaggt ctttatggct tcttcaaccg
    16561 tttactgatc cctacaggat tgcatcaagc aatgaactcc gtgttctggt ttgacgtagc
    16621 aggaatcaat gatattggta aatttttggc ttctgaagga acaaaaggcg taacaggaat
    16681 gtatcaagct ggatttttcc caatcatgat gttcgggctt ccagcaggag catatgctat
    16741 ttacagaaat gcacgtccag aaaacaaagc aaaaacagct tccttgatgt tagcagcagc
    16801 ttttgcttca ttctttactg gtgtaacaga accacttgaa ttctcattta tgttcgttgc
    16861 ttggccatta tatgtcttgc atgcaatttt cactgggatt tctttagcag tgagtgcatt
    16921 cttccattgg acagcaggat ttgcctttag tgccggattt gtcgattact tcctatcttt
    16981 gaaaaatccg attgcgaatc agccattgat gttgatcgtc caaggattag taacagcagt
    17041 gatttactac tttggcttta actttgctat caaaaaattc catctgatga ctcctggccg
    17101 cgaggaagca gatctttcag atgacgatac tgcaacgact aattcagaca ataaatatgc
    17161 ggcacaagca agcaaaatct acgctgcatt aggcggagcc gacaatgtaa cttcgatcga
    17221 taactgtact acacgccttc gtttgcaagt caaagataca ggcctgatcg atcaaaataa
    17281 aatcaaagcc actggcgtac ctggtatgaa gatcatcgac ggaaaaaatg cgcaagtcat
    17341 cgtaggtaca gaagtacaat tcgttgcaga tgagatggca aaactacatg gtggtgctgc
    17401 aacacgacct gcacaaacaa acaccgtggt taaaacagaa acatttgccg gtggaacgat
    17461 cgaacaagat atttacgcta tcgcaaatgg gaaactgatt ccaatcactg aagtttcaga
    17521 tgatgtattc gcggaaaaaa tgatgggtga cggctatgct gtattaccag aaaatggaga
    17581 aatcttctct ccaatcgctg gtacgatcac aaacattttc ccaacgaaac atgctgtcgg
    17641 aatccaaaca gatgctggta tcgaagtctt gcttcatatg ggcatcaaca ctgttgactt
    17701 aaaaggcgaa ccattcactt tatatgtaaa agaaggtcaa aaagtcgcaa gaggtcaatt
    17761 gattgcttta gttgatcttg ccgctattca atctgcaggc aaaaacacgg atatggtcgt
    17821 tgtattcaca aatggcgaca aagtccaaag cttagaaatc gaacccgcac gtgatgtaaa
    17881 agcaaatgat aaaatcggct ctgtttccaa caaagcctga gccatcgtct tccccagact
    17941 tttttatcga taaacaaaca ggagctgaga caaaaatctt gtctcagctc ctttttccga
    18001 ataaaaacgg cgttctcctg ccaactccgc ggtaataagt ccagccaaac gtaacatatg
    18061 aagagctatt ttttatttga ctcttcttat tacttgatgc agaacagctt ttttacaacc
    18121 tctgataaac ggtgttcaaa aaccagttta tcggtatgaa gtcaaattta tgcaaaaatg
    18181 tggaaagcca ttttcacaaa atttttcttc atactcaaaa ctaatcggct ttttcacaac
    18241 ctctttatac attattcctg atccaatatt tcttttaatg ctgcttcaag agaagttaat
    18301 ggttttccca atactttttc taaatcatca gaggaaatag ctaactgatc ctttttaata
    18361 tcatgttgga tcgctaaaaa catgtcagct gcttcttgag ggaatccggc ttcttttaga
    18421 ttttcgacaa acgctgcatc acttgcttca ataatttcta actttttacc tgtcgcacgc
    18481 tctaatgcct tggctaattc ttcatagtca gttagattgc cggataattc taagatttct
    18541 ggagagtcac tttctactag tacttttgct gcagcttctg catattcacg tttcaatgcc
    18601 caacctgttt ttccatttcc tgcagcataa acgaattgac cagtttttaa agcctgccca
    18661 atgataggta attcattctc tacataccaa ttattccgta aaaatgtatg ggaaatacct
    18721 gaatccttaa tcattttttc agtgaattgg tgatctggcg ctaatacact gatcgagtga
    18781 tcggcatctg caaaacttgt ataagcgata taagataccc cagctgcttg tgctgccttc
    18841 actacattct tatgttcggc ttgacgattt cctggaacgc cagagacaaa aagcaatcga
    18901 tctattcctt tcaacgcttc tttcattgag tctaaatcat cataatcacc aatacgtata
    18961 ttaaatccag cttctttcag tgcttctcct ttttcttcac tacgtactag tacatagatt
    19021 tcattttgtg gaaccatctt ttttaagaat tccagcgcat aaccaccaaa acctccagtt
    19081 gctcctgtta ctaaataatg catatttgcc actccctatt ctttttattt gttaagattt
    19141 acagctgtac atttataaat tacaccttta tcataaagag tgtggtaaga taagtcaagc
    19201 aaaaaaaatg aaaggatgac aactgatgaa gtattctctg caatttagtg atgcaatcca
    19261 tgtacttgcc tatattgaaa tgtttcaaga tacccgatca ctttctagtg agatgattgc
    19321 cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc atgagtcagc tcaaaaaatc
    19381 cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc cttgccaaaa gtccagatca
    19441 gatttcttta ctagatgtct atcgcagcat cgaaggtaat acacagctta tccaagtcga
    19501 tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc caagaagctt tagaagaaag
    19561 ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct aagatcacac ttgatagtct
    19621 gatacataaa atagccgttt tggaaaaaga aaaaagacca gaaaacacag gcctcgtaga
    19681 gagattttta taattctctc tactgtgcct gcatttttct gatcggaatc gtctacataa
    19741 attcttttat tctccggggg acaaaagcct tgtcatgccc ctttttcctc tctaatgctc
    19801 aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg ttcaagtagc tgaccctcgg
    19861 cattagttct gaaaaatgca aaatatggaa agctatttcc catttttcct ctctaatgct
    19921 caggtcaaag cgctactttc acgacctcta tattatcatg gtttattgac taccggtatc
    19981 cagatttctc ccatatattt cccgttggta actcccattt cgactacagc atttggaccc
    20041 ccaacatagg cgtaatcttc tacttctctt aaaacatgcc caaaggccgt attcgtcaaa
    20101 tcatttctta attcttcagg cgattctgct aaagcgatta caacaagata cgttcctttt
    20161 gggaatggga tgattcgggt agtgtttgga acatcctgac tcgtttgaac accgacatag
    20221 tacatcattt tcccgttata gggttcgttg actgtaaaga aataatgatt ttcagcagct
    20281 tgtttcaatg catctattgt tccattaccg ataacttttt gctcaaatgc ttgtttctct
    20341 gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt ccacaccaat acccgtcacc
    20401 gtaaaatctg gtttttcttc gatcctatac tttgccattt ctcccaccct ttctattata
    20461 ttaagttcat cttacataaa attaaaggga aatgacacga ttacgctctt ttttctaggg
    20521 atatttttat tttttaacta tttttttgct ttcactgcaa tccaaatctc actgtaaaca
    20581 ttactgaaat cctctcccca ttttgtaaaa gagatctcgg gagcttcgac taactcataa
    20641 tctgaagaag gaagccattc tgcatagatt ttcccccaag tatcttgtaa agtttgggga
    20701 aatggccctt tattaggaaa aatggcccaa gtgtgttctt ctatagcaag catttctaaa
    20761 tcagcgtacg gattttcttt tgtcgtagca aagccaatca tgtgcatcaa actgcccttt
    20821 tcttccaagc gggctccatc aaatccataa gaaacgttga ttacttgatt tggatataaa
    20881 tctcctaact tatgcatctc ttccctttga gtctccgtga tcgtctgcgc taacttttgt
    20941 atttcttgat tgactccttc aaatttgaca ggaacttttt tcgccacacc tgccacataa
    21001 aactgttctt tcttttcgat acgaaattcc atcgattttc ctcctctgac atcaataaaa
    21061 aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc tgatttctga aggcagatat
    21121 cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg tttcatatcc atatctaaac
    21181 gccgtttctg tcactcttga tccatctagg agatcgcgat tagccaaagc caatctacgg
    21241 tttttgatat agtccattag cgacatccct gcaataaacg taaagatgcg ttttaattga
    21301 tattcagaga ttcctgtatt ttcggctatt attttatagg aaagtccttc tgtcaaatgt
    21361 tcttcgatgt aatcgatcaa ttggttcaga tctttaagca tatttatctt cctccttgct
    21421 tgccttttta tcatattatc aaagaaagtc aattacttga tgaatcagga accaatttag
    21481 tcagatgtag aaaatgttgt atggatctaa agaaaattct caagcagcgt ttcgtaacgg
    21541 ataattggta ttatctgcct atctatgttt tacctttaga aaaataaatt ttggggaaga
    21601 cacattctaa gtaaacaaag cggtaaaaat atcttttatt cccttagtta atccgcttac
    21661 tacctactgt acaaagcaaa ttgttgttca aactgctgat cagaacgctg cttggatttt
    21721 tctttgcgat acatcatacc tcttttatca attggaacaa ttatttattt ctaacaaaat
    21781 cacttcattt ttgtcagata aataaaaaac aaaaaaagtt ccatctttaa aacacgctat
    21841 tcttttactt tttctcacat tctctaagaa aagaaaagga gaatgaattt ttgacaattc
    21901 gagcaaaagt gattatcaaa tatgtaaaat cagctacttt tttcttaatc gtttctttat
    21961 actaaatata aataagtgtt tcatgaaagg agaactagat gaataattgg cttgagtatt
    22021 ttcctgaaaa cgttttggaa cgcggttaca gctatcatct gcacggtttt gtccgtcatt
    22081 tgaactatac aagcaagtac ttgtccgcaa cagtttctgg cacggaagat tataaggtag
    22141 tgatcacttg ggatgaaaag accaacatga cttgtgattg tctatatgcc atagaaggaa
    22201 aaaaatgcaa acacatggct gctgtcttat tcgcttacga agaacgtcca ataaaaaaat
    22261 ccaactactc actttccgaa ctctcgtccc ttgtttcctc cgctagttcc tctcttgtac
    22321 gggagctttt aacagagatt cttatagaac atccgcaatt tatcgaacgc ttcaaagtta
    22381 agatgccatt tcatgcaata aattattcag ataaattaac aactatcatc cataaatacg
    22441 atcatattat caagaaaaac aaaaacagga aaacagcgaa gttcatcatg gagatgcgaa
    22501 agttcatcca agaagcagtt gaatcgctca ttcagcaaaa tgcctatctt cccgcattcg
    22561 aattgatcaa tgaagtgatt gctactctcg aaacattcta ttgggagcct gaggatgaac
    22621 gaacccttct tctgatagag gactgttatt atttatggaa agaattatta gcagaagcac
    22681 ctcatgcaga aaaaaggcaa atgttctctt ggttcgtctg ccaagtcgat catactgacg
    22741 cctcttattc aaaacgctac tccataaaaa tcctgaaaga agactttcgg gaaaaagaat
    22801 tttctaacca aaagaaaaaa atagataaaa aaactaaaga aacggtaaag aaagacgatt
    22861 tcaatgaaaa atagcaagta aacgataaca accatcctaa atccacaaga aatacagcag
    22921 accttgcttt aaaaacacga atcatgcaaa ggatgaagta aagaagactt aacgcgtacc
    22981 caatattagt catttgacta ttaggtacgc gttttgtttt ataagtcatg acaaatttcc
    23041 ttcgttgctg ggtagatttt ccggcattgt tgatagattt tatgatactt ttctacattt
    23101 tgtaagagag gttccactgc atctgtatat tggataaaat tctgacaaca actttcaggt
    23161 gtgtcgaacc actctaatct ttaaagataa atattaaaat aacgattaat aatattaaca
    23221 gtctttattt ttcaccacca aaaacctatc tttgcatata ctaaatagac gtatatacac
    23281 agataggttt gtcttgtgaa aaataatgat tatccttacc aaaaaatgtt tgtttttcta
    23341 catgttcgta cttatcaaaa aatatgatcc ttattgaaat tactggctat ttatattcca
    23401 acgacttctt gtgttaattt ttgttatctc atagtaaatt atgtttcatt ttcacttaat
    23461 ttagttgtca cgtgttcgtc aattcgtaaa aacggtaaat atataaacac acttgcggct
    23521 ataattaata tttgtaaaac agctgctcgc cagtctccgg ctgttgctaa aaatcccgat
    23581 ataactggtg gcgtagtcca aggaatttgc actactacat gattaattaa tcccacagca
    23641 gttgcaaaat atgctactgt caaagaaaaa atcggtgcaa gcacaaaggg aataatcaga
    23701 ctgatattaa atacaatagg caatccaaaa ataataggtt cgcttatatt gaatatagcg
    23761 ggagttaccg ataatttagc aaagtcctta taatcttttc tacgactgaa gataaatatt
    23821 gcaatcaata aagcaatcgt atttcccgat ccacccatta ccgcaaaggt atctttaaag
    23881 gccatattga taatatgtgg aatttgctct ttgtttgcat aagctgccat attttcttgc
    23941 atattctgaa tcaaaaacgg atctaacaat gaacctgata ttactgcttg atggatacca
    24001 aatccaaaaa atagattagc aatagatgta attaacaaaa atcctggtaa accagttgta
    24061 attttactta atggctctgt aactatcgtg gtaattagct tatttatatc catattaaac
    24121 aattgaatga ttataaatga caataaagca aacgaggtaa tcgtaataat gattgggatt
    24181 aatacattaa aagactttaa aacagcggga ggaatatttc cggatagctg aatctgtagt
    24241 ttcttattat tagaaagttt aataaataat tctgtagccg ctaatccaac aaatatacct
    24301 acaaacattc ctgaagctcc tgtataggat ataggtatca cacccgtcac ttcaacagct
    24361 ttatccgcat tttcaggagt aaacatcatc tgcataggtg ttaatacaac aaatgtcgaa
    24421 atagcaacta ataccgctgc aatatgattt gtataatttc tgcttgcaca catatgataa
    24481 gatactgctg ctacaactaa taatgtagtt atgcttaatg taccattggc aattgaagta
    24541 ccaatttgtt gtaacgtggt caatgtacta gtatcgacaa tttcccccat gaatcctgtt
    24601 ggttctaaga tcactgaatt aataagtgtc acaaatcctg ctaacatcat aaatggcata
    24661 aatgtagcaa acgcatctcg caaagttctt aaatggatct gattccccaa cttagtcgca
    24721 actataccaa atttttcaaa tacaatgtcc ttcctgctac ttttgcccat attttttctc
    24781 ctttatgctt attgtaatcg attacttttt ccacccaaat aatacatcac ttatcaaaaa
    24841 aagtaaatac ttttaattaa atatatatat cttttttagt ataaaaaaat aagctctgaa
    24901 aaaataattt tcccgagctt atttttcaac aaaaacagct tcaaaaacaa agtcttgata
    24961 taaatgtctc gataccgaat actcgaaagg tttaccagac gatagagcaa caactttgtc
    25021 tatctcaatc ataaattcac ctggatctat ttttaatatt tttgcgtcaa attcattcgc
    25081 agtatctcct ttgatacgta tgtgcgaagt ctttatttcc agacccagtt catttgtgat
    25141 ataagcatat acagatttct ttaaatgttt tggttccaag cctggtatga ctgctaatgg
    25201 catgaatgtt tgctcaatcg agtatggttg acaatcaata aaacggcttc gtacaatatt
    25261 atatacatag tcttttacac tgatacttaa tttatcagct acttttttcg atggaagttc
    25321 aattgagaaa gtatggattt ctgaatctac gtgttcttca ccaaccacgc taaacaaacc
    25381 ttcgtttgga ccaagaactc gtgagttatc aattggtgtt ctgacgactt cagtcccata
    25441 cccacttcta cttcgcaaaa ctccttcgga aacaagtaag tctacgcctt tctttactgt
    25501 taacttgctt gtatgataaa taactgccaa ttcatctcct gtaggaagtt tctcaccaat
    25561 tttatactct ccatttacaa tttttttctt tatatctaag taaatttcca tatacttcgc
    25621 aatttttttc aatggtgacc ctccaatcaa aaacatatct tcatctatac tttaacataa
    25681 ataaaccgat aaaatccaca tcaaaattat acacacaata aaaaagatat atatatttaa
    25741 acaaaactat ttactttaag ttgtaagcgg tgttatcatt aagtggaaac aggaggtaaa
    25801 aaaattatga caactatgaa aaagctaact tttccagatg atttttggtg gggttccgct
    25861 tggtcagctg agcaagcaga aggaaaagga gaaacaggaa aagcagagac tatctgggat
    25921 cgctggttta aagaacaacc ttaccggttt tatcaacgaa tcgattcctc tattacaacc
    25981 gatcacatcc atcaatataa agaagatata gaactaatga aaaaaactgg gcataactcc
    26041 tttcgcgttt ctatttcttg ggcacgaatg tttccaaatg gcggtaccgg aaaagtaaat
    26101 cccaaagcca tttctttcta tcgaaaatta ttttccgaaa tgaataataa cggaatcaaa
    26161 gtatttgcca acttatatca ttttgacatg cctgctactc ttcaagataa aggaggatgg
    26221 gaatcacgtg aagtagttga tgcttatgtt cattacgctg aaacttgttt taaagaattt
    26281 ggtgacttag tttgtcattg gtttaccttc aatgaaccac ttgggcctat tttaggtact
    26341 tatcttgaag attttcatta tccaaacctc attgacttta aacgcggagc gcaagcagca
    26401 ttcttcacta tacttgcaca cgcaaaagca atacaagtat ttaaagaact agctcttcct
    26461 agtaaaatag gcgttattct aaatttgagt cctacttttc ctcgtagtca aaatcctgct
    26521 gatgtgaaag cagcagaaat cgctgattta ttttatacgc ggagcttttt agatcctatg
    26581 gttaaaggga atttttctaa aaagcttatc ctgttattac aagaatataa tcagcttcct
    26641 gaagattata cgaaagaaga tcttgtatgt atctacgaaa ataccgctca aattcttgga
    26701 ctaaactatt acgagccacg tcgcgtcaaa tctcgttctt ctatggtgga tacatctagt
    26761 ccatttttac cagagtggtt tttcgaacca catatcatgc ctggacgacg aatgaacgaa
    26821 taccggggat gggaaattta cgaaaaagga atttatgatt tgtgcatgga tatcaagaac
    26881 cattatggaa acatcgaagc atttatctcg gagaacggaa tgggcgttgc ggatgaagaa
    26941 cgtttcatgg atgatacagg gcaaataatt gatgattatc ggattgagta tatcaaagat
    27001 catcttgctt acttatggaa ggcaataaat gaaggatgta acattaaggg gtatcatctt
    27061 tggacattta ttgattgctg gtcatggatc aacgcctata aaaaccgata tgggctggtt
    27121 tcactcgacc ttactactca aaaaagaaca attaaaaaaa gtggcgaatt ttacaagcaa
    27181 ttaagtgata caaatggatt tagatacgat gtagacttgt tagttgaata atattctaaa
    27241 attccacttg aagtgaacac attagaaaac aagaataatg agaaatacca ataacaaata
    27301 ctttttcttc atacttcatt tatacttgtc agtataagag actgtgacaa atgtagtgat
    27361 cctcagaagt taggtctgga aatctaactt gagaagattt ttttaaacta cgtccagtct
    27421 tttttatttg tttaaaattg aagttgacaa gtcttcatta aaaatttaga atattcacaa
    27481 gtttgacgac aattatgaaa atttatgtcg tgctaaagga gttttgttat tggatgaaaa
    27541 gttagatata aaaactgcga tcaaagacac gttacctacc gtttttggtt atatcggtat
    27601 tggacttgca tttggtatcg ttgggaaagc tgccgggttt catccgctgg tcgtcacgtt
    27661 gatgtccctg ctgatctatg ctggttctgc ccaatttatc acggtcagca tgcttgctag
    27721 ccatagtcca ctgctctcca tcgttctctc gacctttcta gtcaattccc gaatgattct
    27781 gatgagtatg acgattgctc cttatttcaa gaaaaatcgg ctgcttcaaa atctgctgat
    27841 tggcacattg ctgacagatg aaagtttcgc actgggaatg aataaattga actatactgg
    27901 acaaaagtta aactttcgtt ggatgaatac agctaattgg atttcttatt tgacgtgggt
    27961 gggttcttct cttgttggcg cacttttagg gaattttatt actgatccga aaaagtttgg
    28021 tttggatttc gccatcgtcg ctatgtttat cgggttactt tatcttcaag tcatttctga
    28081 tagaaacacc tctaaacgat tacagttgat cctgattggt ctcactttga ttctggtata
    28141 tgtcggactg atttttatcc caagtaactt agtgatttta gttgtaacac tgattgggtg
    28201 cggattgggg gtgtggatca aacatgcctt cttttgagtt tacattgctg actattttag
    28261 gttgtacttt agcaacttgg ctttctagga tcctaccatt tgtcttactg aaaaaattcg
    28321 atttgccgca accgttgctt gagtatttaa gttttgtccc gatcgtcatt atgtctgctt
    28381 tatggttcag cagtctattt acccaaaata tcggacatct gccgcagatc aatctcgaaa
    28441 atgctttggc ttcagttcct acacttttag ctgctattct ttcaaaaagc ttattggtga
    28501 tcgtcttggt aggaattctt tccctttcgt tgattcgctt attataaata aaaaaacaag
    28561 agcttatggc aaattactgt catgcgctct tgtttttatc aaagtcaaat aagaaaaaaa
    28621 tcggcgtatt cttgcttatc cgttgaacgg accactaaca acgacttttc ctaatatatg
    28681 tcctgtttct acgtctttgg ttgcttgttt caagttcttc gcattcatcc catctgaata
    28741 gaccttgctc aatgtactgc ggataatccc ttcatttgct aaagcagcaa tgtgcgctaa
    28801 agcttctcct tgcgtttcga tttcatagtt atagtctgtt ttagcgaaca tatactccca
    28861 gtcgaagctg atagattggt ttttccaaac acctatatct aacggctctt tgatccctac
    28921 gatcgttccc acatgtccaa atggtcggac aaggtgtttg atttgatcaa agtagcgggt
    28981 aatatcgaat aatacagcga catactctac ttgatcgatt cctaattcac gaaaactttt
    29041 acttaagtcg tgatgataat cgattggata gtctacacct gtttttttca gccattcaaa
    29101 attcttcgga cttgcagtcg cgtagacttc taggccagcc caatgcgcta gttgattcaa
    29161 aatcgaaccg acgcccccag ctccgttgat cactaagatt tttttcccgc ggttggcatt
    29221 ttcttctgga gtcagaccaa atttttcaaa taacaattca taagcggtca atgaggtcaa
    29281 cggcaaggct gcggcttctt catctgaaag attttttggt gcaagagcga caatacgttc
    29341 gtcaaccagt tggtattctt gattgcttcc tgctcttgtc gttgtacctg cgtaaaaaac
    29401 gcgatcgccg acagaaaatt tttgcacttc atcacctaca gcaacaactt tcccgactcc
    29461 atcaaaccct aagatacgta aagcatttct tatcccgtta tcttggcgaa gtttcgtatc
    29521 gacaggatta acagatactg cgttgacttt taccagaaga tcccgtgaac tgggtacagg
    29581 tatctgttct ttttcatcaa taaagctttt tggatcatcg atcgacaacc cttcataaaa
    29641 accgactacc ttcattaatt ccttttctga catacgaatt cctccttagc ttcatcaagt
    29701 tggagcatcc atacagtttt catttcaata tatatagtat gctatttgtt ccacttttat
    29761 tcatcataat tattctctta cttaaagtaa actatttgca cttttttggt taaaaaagag
    29821 gttgcgacaa gacttttgtc acaacctctt ttaaacggtg ttcaatcaac tgaccctcgg
    29881 tattcgctca aaaaacgaca aaatatgagg agctattttt gtttggctgt tcttattact
    29941 tgatgcagga cagctttttc acgacctcta attcacggtg ttcaagcaag aaatcattgt
    30001 tcactgaaaa gcgttggatg ttctttttca aaggtgtcta agatctctcg tacttcatca
    30061 gtagatttcg tattcatcaa ctgaactcgc aagtcatttg ctcctggaaa tcctttgata
    30121 tagattttaa agaaacgatg tagtcctgtg atggaacgcg ggatgatttc tgaataatga
    30181 tcttgcagat ctagttgcag acgaagtagt ccgatcagtt ctttttctgt atgttccctc
    30241 ggttcttttt caaatgcata aggattcttg aaaatccccc ggccaatcat gatgccatct
    30301 acgccatatt tttcggccaa ttcttctcct gtctggcgat ctgggatatc tccgttgatc
    30361 gtgatcagtg tttgcggagc gatttggtca cgtaaagcaa tgattttagg gatgacttcc
    30421 caatgtgcat ctactttact catctcttta cgcgtacgca aatggacaga aagattggct
    30481 atatcttgat gaagtaggtg actgatccat tcttccatct cagacatttc cgtatagccg
    30541 atacgcgtct tgacgctgac aggcaaaccg ccagctttag ccgcttcaat caattgtgcc
    30601 gctacttctg ggcgaaggat caagccactg ccttttccac gttctgctac attagggact
    30661 gggcagccca tgttgatatc gattccttgg aagcccattt ctgccatagc aatgctcatt
    30721 tctctaaaaa attctggctt gtctccccaa atatgggcaa ccatcggctg ttcatcttct
    30781 gtaaaggtca atcttcctcg tacactgtct tttccatctg gatgacagaa actgtctgag
    30841 tttgtaaact cagtaaagaa gacatccggt gctgctgcat gctttacgac atggcgaaat
    30901 acaacatctg ttacatcttc cattggtgct aaaacaaaaa aaggctttgg cagctctttc
    30961 caaaaattag tagtcattta tttgttactc tccattctat caagcagtga agtcgcaatc
    31021 tttctcaaaa acattgtcat tatactagga aacaaaaaaa gaagcaaagt gaacagctta
    31081 aaagatgttt ctgattgagc aaaaaaagac tgtgacaaaa atcttatcac aattcctttt
    31141 ccggaataaa tggtgttcaa aagcttgcat ctgcggtaat aagtccaacc aaacgaaaaa
    31201 taggaggagc tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca
    31261 acctctccac taaacggtgt tcaatcagct gaccctcggt attagctcaa caaacgacaa
    31321 aatatgagga actattttcc cgtttgtttc tctaatactc aggtcaaaac gctgatttca
    31381 caacctcttt tctaacttct caatcctctt cctttattga tcaaatacca agtaacggcg
    31441 tacaaaacaa cgatgaatag cacaagtacg atcatcgatg ttgctactgg cacatcgatt
    31501 gttccaagga atccgtaacg gaaaccggag atcatataaa cgatcggatt gactttcgaa
    31561 acagcttgcc aaaatggcgg caacatagag atggcataga aaacgccacc tagataagtt
    31621 aacggctgca agacaaatgt aggcacgatc gatacatcgt cataagactg agcaaaaatc
    31681 ccgttgagca gtcctgctaa cgaaaacaag attgccgtca tcaataatgt aatgatgacc
    31741 atgaaccatg aatacacatg aagtggtaca aagaacaagg aaatgatcgt tacgagagag
    31801 ccgacgagaa tactgcgacc cactccgcca atcacaaagc cccaaatgat cacatgcgta
    31861 ggaacaggcg ctaccaagat ttcttcgatg tttttctgga atttttgaga gaagaaggac
    31921 gaagaaacgt tggcatacga actagtgata gcagacatca taatcaaacc aggcacgatg
    31981 aattccatat atgaaaaacc acccatgtca ccgatccgac caccgatcat ttttccgaaa
    32041 ataacaaagt acaaggatgt cgtgatcaca ggcggaacca gtgtttggac ccagatacgc
    32101 aaatagcggt tcgtttcctt gatagctaaa ctttttaatg cagtaaaata aagattaaac
    32161 atttttctcc tccgtatgat tattttcttc tgtgattttc aaaaacagtt cttctaaacg
    32221 attcgactta ttcctcatag aaagaacttt gattccttgt cttgtcagct gatcgaagat
    32281 tccgttcacc ccttgatttc gttcaacttc gacagcgatt gtctgttcat cttcaaatgt
    32341 acaagcgtat ccttcaatca caggtttggt ctcatatggc gctaaatcaa agataaatgt
    32401 ttcaaattgc agtttggata gaagctcttt catactagta ttctcgatca gttcacctga
    32461 ttggatgatc ccgatgttgc gacaaagcat ttcagcttct tctaaataat gcgtcgtcaa
    32521 aatgatcgtt gtaccatttt cgttcaattc tcggagaaac tcccacatct cgcgtctcaa
    32581 ttcaatatcg actcctgctg ttggttcatc caagatcagc aaacgtggtt catgcatcaa
    32641 tgccctagca atcatcagtc ttcgcttcat tcccccggaa agcatacgtg cacggacatt
    32701 tctcttttcc caaagattgg actgcttcaa atatttttcg ctgcgtttca tcgcttcttt
    32761 gcgagagaca ccgtagtagc ctgcttgatt cacgacgatt tgctggaccg tttcaaaggg
    32821 attgaaattg aactcttgcg ggactaatcc aatctgttgc tttgctcgga ctagatccgt
    32881 atccagatca taaccgaaga cattcacttt tccagatgtt ttattgacta aagaagtaat
    32941 gattccgatc gttgtagact tcccagctcc atttggtcct aatagcgcat agaaatctcc
    33001 ttctttcacg gaaagatcga ttcctcgcaa tgcttcgacc ccacttccat aaaccttttt
    33061 caaattattt atttcaagcg catttgccat ttatttccta tctccttata gacatgattc
    33121 tttattgtat catggaatac agcagatgaa aaaacaactt ggttccagcg aaaaatcagg
    33181 ttgctgggct caggaaaatc tcctaatgaa agacatcaat cggacgaagt cagacaacct
    33241 tttcagaaaa aacaaatcga agataaagga ttactattca tatgtgcaac aaaaggagcg
    33301 tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa cggcggaagc
    33361 aaaagccaag atttttgatc caataaatac tttcgatcac ttcgcctatc ccaatacatg
    33421 ccactgccgc ttttcatcaa ataacgcggc ttccgttttt gcggtttcta ctaaagtctc
    33481 tgggtaatcc aaaactttca gcaaggcaat cgcatttcgg gtccttgaag gtccttcttt
    33541 taatttgaaa tcaaaactga ttccttttcc ttctgttact tgttcttcaa agtggacatt
    33601 ctcacaataa ttctttaaaa tctctgtcaa ttcgatatca tgtgtggcga caaatgctaa
    33661 agatggatac tccgcaagcc accgaacgac tgaagcggaa gaagcaatcc gttcgatcgt
    33721 atttgtccct tttaaaatct catctacgaa gcagtagcag cgttctttgg aagccacttg
    33781 gtccaacaaa cgtttgatcg atttgatttc tgaaacaaaa taactgtcgc cttcaaataa
    33841 atcatcttcg attgccatgg aagtcaacac atgtccaggt tgcagggtaa actgttctgc
    33901 aatcgctgtt tggatcgtct gtgctagaat acagctgatg gctatacttt tgacatacgt
    33961 agattttcct gatgcattgg aacccgtgac taatgtattc ttctgccagt tgaccggatt
    34021 cactaccgct tcttttaaca atggatgata gatatctttc gctgtcacac cgccctcagt
    34081 aaactctggt cggcaagtga tgggcatata agtacggtaa ttcaatattg cagcggctac
    34141 ttctaattct cccagcaatt cccacagctt gatggcttca gttgaatgct tttctaattt
    34201 agtgagaacg aaatgatagg agataaatgg cagcatgaac atgatgttga catattcaaa
    34261 aatcaactct gcttcactcc cactcttcat acgaaatgaa aaacctaatt tagggatgtc
    34321 tcttaatggt ttagtttgct gtttcagctc ttcttgaagt ggtgtcggca gttttgctag
    34381 ctgattggcg gctgaaatcg ttgaaaccaa ataactcatg ctattcagct ctgtttctag
    34441 tgtttgtttc ttcactagat aatagaccgt attgaatact aacccaccga ttgccaaata
    34501 gattcctagt acttgtccta aaagaagcaa acccaaaccc accagcggaa gcaagccaag
    34561 aaaaataaat aaacctacgc gtccaatctt tttacttttt ccatccgcta gatattgttt
    34621 tgcaaaatta tgatcttttt ttcctaaacg agcgaattga tattggattt tttctctcag
    34681 ttgaggattt tcctgataaa aagcaatcag tttttctaac tgctgatctt caccaaaatc
    34741 aaagctgcgt aaacgttgat acaacgcttc tgaacctaca ctagaatagg tactgttgat
    34801 tccttcgaat acttcgaaca tatccaggtc ataccaagta agatcatcga tttcgctatc
    34861 ccatgaacgg aacttcttct ccgtgagcca tgcttccttc aagctttctt ctttatcaaa
    34921 tctcggttga taaggaattt tttcccattt gctacgaact gtttccttta atttcaaacg
    34981 tgaaaaaatg tctaaagcaa ctaataaaat aacagctgca ataataatta aaacgataaa
    35041 ttctctttga cccatatccc tctccgttcc tttatttgtt agctttagta tagcactgtt
    35101 gcgctatttg aaaagagggt aaaaaaacac ctttcaaaat aaaaggtgtt tttttcttgt
    35161 atattacata tttatctctc atttatcaaa attgacaaat aatcataggg aggaattgtt
    35221 gttaattctt gtttattctc cagtgcattg acaactgtcc caagggaaag gatagcctca
    35281 ggtactattt tttcttgttc tgttggatta gctaagcgaa gaacaaatcc ttgttcatga
    35341 aaataagaag gataaatcga tgatacaatt aagtcttcag gtaattcaat caatgaaaat
    35401 ttacgaggaa catcaagttc attttgtaat ggccaaatct tgttatctaa cctgtgaata
    35461 aatacattca gtttctgctt ttgataagaa atagattgtt ctaaccgttt ttctgcctgt
    35521 tttgccactt tgaactcatt aaatcttcct tcttctacat taaatccaaa agtgacttta
    35581 tactcaccta tctcttgagc tagcggtgtt tccatcatga catgcccttc atttgtcgta
    35641 tctcctgaag ctcgcccagg tcgccaagca agattaggtt ttccaagttc ccctgttgtt
    35701 gaaaataagg ttatgattaa ttgattttct atacgttcat actcttttaa accatctgca
    35761 taaaacgtaa aataatgatc attttctgcc acagagacac tcttatcgaa tatttctaaa
    35821 ttaacaggtt tctctaccat agtttctgac caattcggag gaatgacatc aggggtattt
    35881 tcaataaatc cgttttgaat ttgtgcaatt gatttttcag atttatctaa aacattaatt
    35941 gctaagcgca tacgatgcga gtaaacagta ttatgaattt tgagtgtgcc ttcaacgatt
    36001 tgactttctc ccagactgaa cgatatttca taagatattt cttccatttc gggtttttca
    36061 gataaacgat cttttaaatc tttaggaagt tgagcttttc cgtaaacaac taatgtttct
    36121 tgtaaagaat ctttatatac tttagctgtt tctaatttta gagatagttc tgtatctcct
    36181 tctaatggtg aataatcata cgtatcgcca tcatttgctg aatcgatcaa atgaacgaaa
    36241 tcaagatatt gtctatctcc aactatcaaa ttcaattgcc catctttaaa agaaagttta
    36301 tatttattgt tacttatctc agttttgtct atctcgattg ctgtttctaa tttttcatta
    36361 tttttctcaa attcaacaac agtgtatcct agtgctggca catttacatt tatttttatg
    36421 tcaagttcat aataagctgg ttcatcaaaa tattcgaaac ctgtagcaat catccgataa
    36481 gcatttttcc gttctggaaa ataaacttct ttttcaatga tattataggg actacctttg
    36541 aagtgtattt tctttgaatc agctactaca tgcacgattt tcgatccact ataattctca
    36601 gtcgttgtgt tgaaaacaag gacttcattc gattttagct ttaatgcatc agccatccgt
    36661 tttacaataa ggttttcgat tccgtcagct atctcattag cttctttgat tcgatggaaa
    36721 atatcttccg caacattatc tgaaacacag ccaccaatac tatcatgagc ctggttttgc
    36781 aaaatctttt tccataaccg acgaagtagg cctttactga tatggatacc atttctttct
    36841 gcaatcagca tgagcggctc aactcgtttt agaatttttt gttccaattt aaaattttct
    36901 attttcattt ttgttcttac tgagccaata gaacgatgaa cacgagagta aaccggctga
    36961 cgaagttcac ctttatattc aggtaattct tttttgtttc tgataacttc tacataagaa
    37021 ggataatctg aaataatatt gtggaattta ctgtatttat tcaacttctc tacgacttga
    37081 tcaaaattta aaatcattga cttttgatct acacccgaag gtactaaaat atctttgttt
    37141 tttccttgca tatgaagcat ttcaactgct tcatccaact tttcttttgc aaattcagga
    37201 atatctttaa ttgcgtctaa ggtcatcatt ccagtcatat aaccaaatgg aaaattcatg
    37261 gcataaacaa atttatctcc caatcctttc cagataaaat aaggagatgg aaccatcgtt
    37321 tcaaagttta atcctcgcca acacatgaaa ttatcgattt ctacttgatg caaaagtgta
    37381 ggcaaattcg cattgaaccc aaacgtgtca ggcaaatacc ctaccatcat tggatctcca
    37441 tatttaagga tcgtatcact gattccaatc attaagtttc ttaaaattga ttcagcatcc
    37501 actaataagg catctgtttg tgcataccac ggtcccacga atagttgtcc tgttttcatc
    37561 agtcgttgga taaccttaag cttttgcgga ttgatctcca aatactcatc gacgattgaa
    37621 gtttgtccat ctaaacaaaa gtttacttta gggttccttt ccaattcatc tagaacttca
    37681 gtaaagacct gatcagacaa tacgatggca tcttcatttg taaaatacca ttctctgtcc
    37741 cagtgcgtgt gttgaattat atgtgcattt accatatcag attctcctac tttccttctt
    37801 ctactgaatt tacttgttgt tcttttttat acttgatgga ttttagtgca ttgaccatta
    37861 acgctgtaac cactccccca ataacaattg atactaaata taaaggtata ttcgtaacaa
    37921 aaggaattgc cataaaggtt gaaagcattg tttcttgagt aacaccaaaa aatccattta
    37981 gaccacatgc tactgcagtg cccaccacga tgcttggtat tactcgtaaa ggatctttca
    38041 cggcaaacgg gatcgtccct tcagtaatcc ccacaaggcc cataatcata gctgtctttg
    38101 cattatctcg ttccgattca tcataaagtt ttttgtttaa aattgttgct aaaaacattc
    38161 caaatggcgg aatagcaatt cctaataaca tggctgtact aggtccaaag cttccgcttg
    38221 aaaaagaagc aaccccaaaa gcatatgcga ttttattgat aggtcctccc atatcaaacg
    38281 ccatcattcc tcctaaaata gccgacatca aagcagcatt tgctcctgac atgccttcta
    38341 gccaattagt cagtcctgtt gtcattgctt gaataggcgt agctagtaca taccataata
    38401 tgattccaac aactaatgta gtaacaaaag gaatcagcat aattgatttt agactaataa
    38461 cttgcatcgg tacttttact tttttcaatg cattagctaa atagccacaa gctaatccag
    38521 caaccattcc tccaataaat cccataccaa gattttgaca catcatccca gtgataaaag
    38581 ctggtgctag accgggacgg tcagcaattg aatatgcgat ataggctgaa atcatcggta
    38641 cgataaactg taatcccgtc tgaccaatca ttcgcaggac tccccagaat gtatccgtct
    38701 ggtcccaaac acctgtgcca ccaaaaatga ctgcaataga agttagtaac cctgctgcta
    38761 cgacaagcgg gatcatatag gaaaccccac tttggaaatg atttagaatt tctcttcctt
    38821 gtttcttgaa ttccattagt aactccccca cgatatattt tttatttgtt aattaatgca
    38881 attgcttcat caatcgtctc ttcaccatct tttactacct ctgaggtccc tactgttaaa
    38941 atcggtttac cgtcaaagcg acctcgttct gaaacatttg tatctactgc aaatatgaca
    39001 acatctgcct cggaaacatc cgaaattgaa agtttgtttt ctatccccat agccccctgt
    39061 gtttctactt taatatctaa ccctttcttc ttcgcaaact tttctaaatt agcttttgcc
    39121 atataagtat gggcaatccc tgcgatacat gctgttactg ctactatttt tgtcatatga
    39181 aattcctcct tttaaaatga tagagctttt accaattctt ttttatttct cgaatctttt
    39241 attcttttaa caaactcgtc atccatcaat cttccagata attctgctaa aatacgtaaa
    39301 tgattagtac ctttatcagt gtcttttatt gctaacaaaa agacgagatc aactggttga
    39361 tcatctaatg cgccccattc aacagaccgc tttaacttgg ctacagccac tgttgattca
    39421 attactgcta ggcttttgcc atgaggaatg gcgatatttt tcccaattcc tgtggtcata
    39481 tggttttctc tgtcaaatac gtctttttga aattgtttgt ggtcagacac aaacccatta
    39541 gtctctaaca atttcgataa tttttcgact acactttttt tatcagatgc atttaaatct
    39601 atcactatat tatttatatt gattttttca ctgatcattt ataagccttc tttcaatata
    39661 taaactaatt tttcaaacga cgaactcgtt tttaaatttg ctaataactc atgattcgaa
    39721 gcgatttcat tgaatgtttc ataaatttta ttcaattcag gttttacttt ttcattaagt
    39781 gcaaaaaaga aaacagaatg aacaagtgtc ccatcccaat caattccttc tggattaacg
    39841 tagacacaga ttactggctt ttttataaaa tctacttcga tatgcggcat agcaaaatca
    39901 ttcatcgctg ttgaagatag tttttctctt ttgattgctc cctctagtat cccttctttc
    39961 gcgtaatttt cttttaccaa ttttttggta attatattta aaacgttcac ttgattatcc
    40021 tttatttggt gggtaaaaaa gcaaaatcgt ttatctaata aatttagaaa agcatcttct
    40081 gtttgttcat ttaactgtag atactgtttt acttttctga catctgcccc taacatcaaa
    40141 ggactaacaa caataacagg aaaatttgta ttttcaatcg gaatcgtgct tataacaagt
    40201 tcatcagtga cttttctatc ttgtagttca ttgatgctta gtacatcttc tatctcaacc
    40261 atatctgcaa aaccgttatt tattctttgc tctaataatt ttgatgttcc atatccgcta
    40321 ctacaaacta atatcacttt cgttttgtca ggtttgtaac gatccaaaag tgattgaata
    40381 tggagtgtta cgtaagcgat ttcatcttca ttaaaatgta tacagaatct ctcttcgatt
    40441 tcctctaata aatctacact tatcataaat gaccttttaa aagaatattt gattttgtcc
    40501 gtataagggt tatagatatt tactcccaat ttgagtcttt taactgctgc attgagatgt
    40561 aatactagat tattgatcaa ttcttcatca ggataaaatt catttaattt aattcttact
    40621 aactcttgta gctcaacacc catatctaaa taggaaagct tcgtttgatc taagtcgtga
    40681 ttcatagcat ttttttcaat cgaagtaatg tgaatgtcaa cataagcttg ttcatctatt
    40741 ggcacaataa ttgaaaatgc tttttcaatc attttgatta aaataagtgt attctttgag
    40801 atttcttctt cagaattatt actacgtgat aagaaattgc ttgtttcaat cctttctatc
    40861 gcaatagcaa ggtggatagc taaagtttga aattcataat ctgtaaattt caattgtgtc
    40921 ttattcatgt atcgattaag caattcggct acttttttca atatgtcctt atttaagaaa
    40981 ttattcgctt caccaatgaa attgatattc aagtctaaga gatctgtttt actgttagat
    41041 gctgtaaagc caccccaata atagttcaca acttctgaca tcaaccttct tttacttttt
    41101 tcatcagctt tgatgcgcac gccatttcga tctgaaacta aggacatccc atgcttgttt
    41161 agtctttttc taacatcttt cattgtgctt tctaccgtcg acctgctcac gtataattcg
    41221 tcagcaagat tttgaatctt tagagaatca ttagtattca ataatttagc aaacacataa
    41281 gttagacggt cctccggaga gtctgcgata ttgattttat gactggataa taaatttcga
    41341 agtgtttctt tttttccaat aagcgaaacg ccttttttag gttgaaccaa catttgtaca
    41401 tctggcattt tttggattat ttctttcaaa attaaaatat ctttgctaat tgttttcgta
    41461 gatacatata attgttctga taattctttg taagttgtgt gctcattttc aatcaaaaag
    41521 tatagtattt tcatttgccg ttcgctaaat tcgatgccca ttatcttcac ctcctgaata
    41581 cagcttaagt gtacaattat tatctctatt ttcatacaga agaaagttct tgattaatgt
    41641 agaagtttct aatattcttg attatttcaa atcaataaaa aagcctgcaa tatttatatc
    41701 acaggctttt ttctctatta aatatatata agataataca tttttctact agttctcact
    41761 aatcttgtat aattaaaccc tccgcaactt gacggagatg gagaagatgc ccccgtctaa
    41821 tctagcggtc atctctcctc ccattccttc caccaatttt tttgacaggt aaagcccgat
    41881 tccgctagat tccgtatttg tgcggctggt attttcggta taaaaacgct ggaagacttt
    41941 ttcaacagag gtttgcgttc ctggtttgat aggattggcc actgttaatc gaatgaatgg
    42001 atcctctttt gaaaatgtca cctttgcttg tccatctgca taacgcaata aattctgtat
    42061 gatattttgc agcactcgca gcaacatgag cggatctgct aatacagttg tatttatcga
    42121 gtgttcagcg aacgctacct cgatattttt ctcagaaaat tgttcataaa aagagaaaaa
    42181 tacttcttcc acctctttag aaaaagaaag cgtatggaga tccatttctt tttgcttcgt
    42241 ctctattcga gcaagatcat aaaactgatc cgtcatactg agtaatcttg caacagattg
    42301 tttgatgatc gttaaatact tctcccgttt ctccgtatcc tctacctgtt ccagtaattg
    42361 tacataaccg ttaatagcag tcaaaggagt tctgagatca tgagaaaggc cgacgatcga
    42421 tagtctgatg ttttcttcca tttcttgaaa tgcttgtcct ttttgttcat tttcatccaa
    42481 ccatgtattc agtgcatcta ctaggtccat tagattcttt tctcgaaatt cgactgaaag
    42541 acgaccacca tattcttgtc gttcagaaag agtggcgatt ttcttagtta atctcttgat
    42601 ttccctttgc aggaagaaaa taaaacttcc cataaagata acaacgagaa gcaacagcca
    42661 tttaatcaaa tctaaacccc actccccaca ccgtatgaat atacacagca tgtgcctttg
    42721 ctagcttccc tcgaagattg gaaatatgca tattcactgt tttctcacta tcaaaatatg
    42781 gttcttgcca aactgtttca taaagatttg ctcgcgaaaa tacttttttc ggatgttcta
    42841 aaaaaagctt cagcagatcg aattctcttc ctgtcaaatg gacagccaca ccattcacat
    42901 ttacatccct cgactctttg tccagtaaga tttccttgta atagatgcgt tgcgacagat
    42961 cttttacttg gacagaagtc tgatgacgaa gttggatgcc gattcgtaac aaaagttctt
    43021 cgatatcaaa tggtttcgtc acatagtcat ccgctcctgc tgccaacaag gaaactttat
    43081 ctctttgatc gctttttgct gaaagaacga tgatcggaac attcgatgtc tgtcggattt
    43141 ctgctaacaa tgcttcacct gaaagccctg gaagcatgag atctagaagg atcaaatcga
    43201 caggatatgt gcttaacaat aattttcctt ccgtacctga ataagcatca agaagtttgt
    43261 atctctgttc aagaacctcc tccagtaagg aatgaacagc ttcatcgtct tcgataatca
    43321 aaatagtttc cagcaggacc acctacttaa tgtcagattt ttggaaaata aacattccta
    43381 gagctgatga taccacgatt gttactagac tgaccagaat cattttcggt gcttgcgaat
    43441 aagttgcttg ttgcgcaaag tccgtataca tgagccacgt ttccgtaaac cactccgtta
    43501 gaaattccaa gcctttgatt tttgcgaaaa caccgggaat gaaggccgtt cccatgatat
    43561 aaagaaaaga aagaagcaaa ctgacactgg tacttctagt gatgaatgtc aaagccactg
    43621 gaacagataa tgtccctaat gtcagcagaa gcaatacagg aaatactttt agaacataat
    43681 ttccatagtt tttgattccc tcaacttcac caaatccgaa agcaagtgtg taagcaagca
    43741 tggctagtcc cgtgatcaaa accacgccaa gtgttgtgat caaaagcgta acgagaagtt
    43801 tcgacacata ataagtcatt cgattccgtc ctaaagataa cgtattgcga atcgtaccgt
    43861 tttgaaattc ttccccaata taaaagcacg caaatgctgc gaaagccaga agaatccatg
    43921 cagccatttt ttctaccatt aaaatccctg ttgcaccgtt gatgactgta tccgttgctt
    43981 ggtttaattc attgccgtat tttgtatgca tataccattc gttccaagaa taaaaaagcg
    44041 gaagtacgac catcagtcct agtgagaccc acattttacg gctcttccat acttttattt
    44101 tttcagcagt taatagatta aacatgtgga ttgcctccag ttaattgtaa gaaataatct
    44161 tccagttttt gcccaactag gtgaatacca tccacaggaa cttttgcttc taccaatgct
    44221 tgattgatgg ctgctacttg gtcaattcct tcaaaaagct ggataacacg gctagattgt
    44281 acaaaataat ccctataacc aagagagtcg agaaccgtta ctgcttgttc cgtcgccgaa
    44341 gtgtcaattt ttataaattg acgagattct tgtgccaatt cttctttcga taattctttg
    44401 atcaagtgtc cttcatgcaa aataccatag tgagtggcga tctgtgacaa ttcatctagc
    44461 aagtggctag aaagcaagac ggtgatgccc cgttctttta ccaaacgttg gatgatttct
    44521 cgcatttctg ccatccctgc tggatccatc ccattcgtcg gttcatccaa aatcaaaaat
    44581 tctggattcg tgatcagtgc atttgcaata gctaaacgct ggcgcatacc taaagagaaa
    44641 ttctttgctt tctttttccc tgtattttcc aatcgcatca ttttcagcag gtcttcgatt
    44701 tctctatccg acacaccgcc gttcgctgct tggatacgta ggttatctct tgcagttaat
    44761 tctggataaa gagcaggggt ttcaatcgat tgacccatac gtcgtcttgc tgcctgcaaa
    44821 tccgtcgttc caaataattc gatcgaacct tcatcaatcg agatcaaacc cataatagtt
    44881 ctcataaagg tagacttacc cgctccattt tccccaatca atccatagat cattccacgt
    44941 ttgatttcga ttgatacttt atctaatgct ttggcagcac cgtatttttt ggttatacca
    45001 gttgctttca agaccgtttc atttccaaaa tccatactta tccttctttc ttattgatga
    45061 gtgaagtata gttgacgggt ataaagaaag cagccagaaa tgtataaaga aagtgtaaat
    45121 tttccaattg aatgtcaaaa aaaacaatcg gacaatacgt gtctttccta ttatcaggca
    45181 gtttgttata cgcttgtatc agtttcctga ttctttcttt tcgaccaaag tcgtttctct
    45241 gtattcctct tcactgaaaa tttttgcttc tttcagatca agcttgagta attttaccag
    45301 accggttata aggataacta tagcaagact ccctcccaga aaaattagac tgtctcgcag
    45361 acgtggttgc gttgtcttcc aatcaaagag cgcaccaaac agtgctaatc caagtggact
    45421 ggccaccatg gtaatcgttg ttatcgttga cataagtcgt ccttgtatat gcgttggaac
    45481 ttctcgctga agccagacca tataaaaagc aaaagaaaac attaatcctt aaaaacggac
    45541 ttatgaaaaa taatacatgc cgtttgggat ttacaattag ctaccaaata agaggttatg
    45601 acaaaagact tttcacaatc ccttcttccg aataaacggt gttctcctgc caactcctcg
    45661 gtcacaagtc acaatattta tcaaacatga gaagcaattt ttgtaaattc cttcttattt
    45721 cttgaagctg accacttctg tcacaacctc agaagcggat aaataatatt gtttgatgat
    45781 actttatctt tttcccgttt gtttatagat cgaatgatat tatagaccaa gaatcctacc
    45841 tattaacata gctaaaaaca caaaaaaggc actttccaaa ttgtggaaag tgccagaaaa
    45901 gttaggatta aggtaactgc gctcagcatt gcttcgccca gtacgattct cgtaactcgt
    45961 gaactcgaac gataatcgca attaacgttt tgagaactgt gaagctttac gggctttctt
    46021 aagacctggt tttttcttcg tatcattgaa taagtttgaa aaaccttgat ttataaaggt
    46081 tttcccgtaa atatatttta ttatatttga ttaaatttga aatgtttgtg ttctaaaatg
    46141 tgttctaatt taaaggcagt atatttcgta ttttagatta aatttttagg ctcattcatt
    46201 ctcaaatcca ttctattcag tcaataaaaa ttttaaaaag actttataaa caaagatgtt
    46261 caagcgagca tcttattttt ttgtgcttaa tttgaaagga gaacatttca tgtataaaaa
    46321 acaaaaaaag aaattatgtg tattaactat tttgagtttg gctgttcaag caattgttgg
    46381 agcaattgct cctacgatta cttttgctga tgaaattacc catccacaaa cggtaaccgt
    46441 agaactagat ttagcacatc aatatgctgt tgaaggaact tttagtgatg gtcgtccaat
    46501 gtcagaagtc actgttccgc attatgcagt gtacaacggc tttaaacaag atattttctg
    46561 tattgaacca ggagtcccga tttacaatga gttcactcct ggctatgaga aaaacccgtt
    46621 accagatatg tccgataaag ccaaattagt ttccgtttta tggaaaaaag taggtacaga
    46681 tgcagatact catattgtgg cacagaagat gatctggcaa gaagttaatg ggtataccct
    46741 tcactcaata aaacgatcag atggtagtgc cgtaaatatc gcagccattg aggcaaaaat
    46801 aaatcaagcc attgacgatt atcagaagaa accaaccttc cataatagta cggctaaaac
    46861 agtattaggg caatcgacta ctgtgacgga tacgaataat ctgaatttgt cagagttcga
    46921 tgaggttgtg gaaaatgccg caaacattga ttatcgtgtg aatggtaatc agttgataat
    46981 caccccaaat gccaattcaa aagaaagtgg tgtgctgacg cttaagaaat ctgctggtac
    47041 cggaacacct gtcgcctata aaaaggctgg ccaacagact ttaatggccg gggcgattga
    47101 taaacctaat acctacacaa tcaaaattga tgtggaaacg gagggttctt taaagatcaa
    47161 aaaagtcgat aaagaatcgg gtgatgttgt accaggaacg gttttccatt tagactttgg
    47221 aaaaacttta cctgcaaaag acgtgactac tgacaaagaa ggcattgcta cattggatga
    47281 gattcctcat ggtacaaaag taaccattac cgaaaaatca gtaccggcgc cttatacgat
    47341 tgataccacc cccatgacta ccaccattaa agcaggcgaa accatttacg tgacttcaaa
    47401 aaacgcacgg gaaaaagggc aaatcattct ggataaaagc ggagttgaaa cagggagtga
    47461 tctttggaat gacaattatt ccttagctgg taatacgttt gccattcgca aagacagtcc
    47521 aaccggtgaa atcgttcaag aaatgaccac ggatgaaaac ggtcatgcgg aaacaccaaa
    47581 agagattgct aatgcgttgg aattgggaac ctattatgtg accgaaacta aagctagtca
    47641 tgggttcgtg aatacgttca aacctgtaaa agtcgaattg aagtatgcca atcaaaccgt
    47701 agcccctgtt accagtaacg taaaagggca aaatcaagaa gtcactggcg aaaccacttt
    47761 gacgaaagaa gacaaagata ctggggataa agcacaaggt aaggcagtct ttgagggtgc
    47821 tgaatacacc ttgtttactg ctaaggatgg aaaagctgtt aaatggagtg aggcttttaa
    47881 accagagtta gcgaagggaa cgaaaggttc tgatgaaacg gtcactttga ctttagacga
    47941 aaagaaccaa gttgccgtta aacatttagc tatcaacgag tattattggc aagaaacaaa
    48001 agcgcccgaa ggatatagcc ttgatgaaac aaagtatcct gtatccatca aaaaggtgga
    48061 tgatagcgaa aaaaatgccg tgattacccg aaatgttacg gcaaaagaac aagtgattcg
    48121 ctttggcttt gatttcttta aatttgctgg atcagctgcg ggcactaccg aaactggctt
    48181 caatgatctg acctttaaag tgtcgccatt ggaagggacc aatgaaatca caggtgccga
    48241 agatgaagcg accacagctt ataacgagca attagggttt gatggttatg gcaagtttga
    48301 aaatcttcct tatggggatt atttacttga agaagtagaa gccccagaag gttttcaaaa
    48361 gattacgcca ttagaaatcc gttctacttt taaggaaaac aaagaagact ttgtgaagag
    48421 tgagtatgtc tttaccatta ccgaacaaga ccaaaaacaa ccaattaaaa cggtgaccgt
    48481 tccttacgag aagctgacga acaaagcatt ttctgttagt ttgaaccgtt taatgctcta
    48541 tgatttgcct gaggaagaag atagtttaac ttctcttgcg acttggaaag acggaaacaa
    48601 agaattaact tctctggatt ctaccgagct agttgataaa ttgagttaca atctacatga
    48661 aatcaaagaa gactggtatg tggtagcgca agccattgat gtggatgcga caaaagctgc
    48721 ccaagaaaaa gatgaaaaag ccaaaccagt ggtgattgca gaaacaagcg caacgttggc
    48781 gaacaaagag aaaacaggaa cttggaaaat tcagcataaa ttaaccgccg aacaagtttt
    48841 aaataaaact attgtcttat tcaactatgt gtatgaaaat aaggaagctt ttgaagcagg
    48901 cgataagcca gtagcgaagg atgttagctt gaataaccaa gcccaaactg tcagttgtac
    48961 agtggaacac catgtttcta tccaaacaaa ggcccaccta gaaaacggtt ctcagacctt
    49021 tactcatggt gatgtggtgg atatgtttga tgatgtgtcg attactcatg atgtactgga
    49081 tggctcaaaa gaagctttcg aaacaattct gtatgcttta ttaccggatg gtacaaacaa
    49141 agaaatttgg aaatctggca agattgatta tgaagtaaat gataaagaat tcaccaaaac
    49201 tgtgcttgcg aaaaaagtag ataccggaaa atatccagaa ggaaccaagt ttacttttgc
    49261 ggaaatcaat tacgataaag atgggaatat caatggaaaa cacaatgaag atttgaaaga
    49321 aaaatctcaa accttaacac caaaagaagt tccaaccata ctaagtacgc cgaaacaacc
    49381 ggaaacacca actgttccaa gtggctctca agaatctagt cccacagtga agaccttccc
    49441 tcaaaccggg gagaaaaatt ccaatgtttt actgttcatt ggttttactt tgatttttgc
    49501 gacggcgggc tattatttct ggaatcgccg gaactaaggt gatgagatga tacaagtaaa
    49561 tcctaagaac caacgtgcgc gaccgcctcc taaaaaagta gtcgcgctat ttttgtatcc
    49621 aaaactaaca atgaaaagag gaaaagaaga tggaattgaa atttgtcgtg ccagatatgg
    49681 ctgaaacctt tggaaagtta agttatgccg gtgaaggaga aattataaca gaaggatatg
    49741 gacggaatac tacggtgatt ggtcgcagtt atcatttgta ttccagtaag caacgggccg
    49801 atgatattga ggtggtagta gctgcggaag ccggtgaaaa ggattttgat caagaccaac
    49861 cgctaaaagc cgtgaatccc catttggttg ccaaaggcta tgagattgag aatcgtgggt
    49921 ttactgatta cgtgttgtat gttgatgatt tagtgaaagc ataggaggaa aagaagatga
    49981 gattaacaga aggtattgtc gtagattcag gtttaacatt tgggaagttg cgtttttccg
    50041 cattacgccg agaagtacgg aagcaaaatg aggatggaac aattggtaat gaggtaaaag
    50101 aacgaaccta taatttaaaa tcctctgcac aagggcgaat gattcaagtt agtatcccag
    50161 ctaatgtacc cttacgcgag tttgcttatg atgcagaggt agagttggtc aatccaatcg
    50221 tggataccgt tgccaattat gtttttcgag aaggaactac cgttaattgg ttcattaagg
    50281 cggatgattt agtcttgaag cggcagccga atcaaggaaa tcctacgaac caaaatgaaa
    50341 gaaagaaata ggtgaagatt atggaaatta atgttgaaca tattttagat tgtctcgatc
    50401 aatatggaaa aggcgagctg actgaggaac aactcgttaa agcattaacc tctgatgaaa
    50461 aaatgtttct gattatacat caaggtttac ttggagaaaa tagcgacagt gaagaagact
    50521 ctgatgtact agactggtta ggagaagaag agtctttctt tatagttgtc gaagtaaatg
    50581 aaaacttatg tcggcaggca gaatccattt tggaagaaat tggtgtggag atgccggatg
    50641 ctattgaagg ctttttaaat caattggttg aaacgaaaca actcccctcc tcgtagcagt
    50701 aaatgactag cataactttt tgaaattgcc taatgaaatc ctattgggct ttttcgattg
    50761 gaggtggaaa ccatcaaaat gtacaaagga catcgcatac gcgcaggaga tcagcacttg
    50821 gtttatcact ttgttcttgg ctggctactc gctctgttca tcggttggat gagcgtcttt
    50881 tattttcaag agtttagaca atttgatatt tctaagctat cactttctac tattgaaatc
    50941 gtttggtcta taaaagattt agtatgtctg cttggaagtc tcgctttttc aggagctatg
    51001 atattgcttt atattcactt ttttcttgat cattggcgaa gcttgtggca tcgacaaaag
    51061 ctagctcgga tgattctaga gaaccattgg tatgaagtga aacaaactca aagtgaaggc
    51121 tttttcaaag atttgaatag tagccgaacc agagagacta tcagttactt ccccaaaatc
    51181 tgttatcgaa tgaaagatgg attactgtct attcgcgttc aaatttcact tgggaaatac
    51241 caagatcagc ttttaaaatt ggaaaagaag ttagaaagcg gactgtattg tgagttagta
    51301 gaaaaggaac tcaaagactc ctatgtggag tatactttac tgtatgatat gatcgccaat
    51361 cgaattggga tagacgaagt agtggcagaa aatgggactc tgcgattgat gaaaaatcaa
    51421 gtatgggctt atgattcttt accccatatg ttaatcgctg gtggcacggg tggagggaag
    51481 acctatttcc tcctcaccat tatcgaagca ctattgaagt cagatgcaga attgtttatc
    51541 ctcgatccca aaaatgcaga tttagctgat ttaggtacgg tgatgcctca tgtttattca
    51601 caaaaggaag aaatttctgc ttgtgtggaa gatttctatg aacgtatgat ggctcgtagc
    51661 aaggcaatga aagaaatgtc taactacaaa acaggagaga attatgccta tcttggactt
    51721 ccacccaact ttttaatctt tgatgaatac gtggcttata tggagatgtt aacgacgaaa
    51781 gaaagtgcgg tgattttgaa taagctcaaa caaatcgtga tgttgggtcg tcaatctggt
    51841 ttctttctga ttttggcttg ccaaaggccg gatgcgaaat atttaggaga cggaatccgc
    51901 gatcaattca actttcgcgt ggctttgggt cgtatgagtg aactcggata ttccatgatg
    51961 tttggggagg tcgaaaaaaa cttctttatg aagcacatca aaggtcgagg ttatgtggat
    52021 acaggtggca gtgtgattag tgagttttat acgccacttg taccaaaagg gtatgatttc
    52081 ttagattcaa ttagtaaatt agaaaagatg aatgattgag tgatcttcaa tactgacttt
    52141 atacttcaag taacgtataa tacttttata tagtaggaag aaaggggata attaatatgg
    52201 aaagtaatga ttcttattta gagtatgcaa aagcaaataa ggataagttt atttcttata
    52261 ttatcaaagg gaaatccccc gaagttggac gagacgcagt ttttatggca gggagtcctg
    52321 gggctggaaa atcagaggtt gccattggat tagctgagaa ttatgataac catgtgatta
    52381 ttgatgcgga ttactttcgc acccagtttc ctgattataa tggaaaaaac tctagtctct
    52441 ttcaaaaagc atcttcttgg ttggtagagc aggcatttag atatgtctta gatcatggct
    52501 attcttttat tctggatgca acttttgcaa tattaagtgc tgaaaaaaat atctcgcggg
    52561 cgttgaaaaa acattttcga gtgacgattt tctatgttta tcaagaccct aaaatcgctt
    52621 ggaaatttac acaagaacgt gaaattgcag agggacgtca tgtgccgaaa aaggcattta
    52681 ttaacgcttt tttcaaatca agagagaaca ttgcaaaagt aaagagtaaa catccagatg
    52741 tattgcttca tatcataata aaagattata cgaataatat ttccgaagtt cattatgcta
    52801 cggataatct agaattattt ttaccactag ggtatagtag gaaagatttg gaggttcaat
    52861 tacatgactg agaaagaaca agtaacgaaa attgtaaaga aatacaataa gagcattgcg
    52921 gatttatcgg aaaatgctac tgcaaaagag ttcaaaacgg tgattaaata tgtagccgat
    52981 caggccaatg aaaaacaacg gaaattagtt ggattaaata aaaaatagta ggacaaatta
    53041 ataatgtatg agccaagagc aaaatgttct tggctttttt ctttgcaatg aatgaggtaa
    53101 tgtatgagat ttttagattt attcgccggt attggtggct ttcgtttagg tatggaacag
    53161 gcgagccatc attgtatcgg tttttgtgaa attgataaat ttgctagacg tagttataaa
    53221 gcaattcatg atacaagtaa ggaggtggaa atgcatgaca tcacaagtgt atcagatgag
    53281 tttattcaat ccctcggacc agtggacatc ctttgcggcg gatttccgtg ccaagctttt
    53341 tcaattgcgg gaaagcggca aagattttcc gatactcgag gtactttatt ctttgaaatc
    53401 gctcggttca ccactcttct ccgacctaag cttttattcc ttgagaacgt ccgaggattg
    53461 ctcaatcacg aaggaggggc tacgttcgag acgatcctcc gaacgctgga tggattgggg
    53521 tatgacgtgg agtggtaggt gcttaactca aaggcctaca ttccccaaag ccgggagcgg
    53581 atattcctta tcggacattc tcgagacgca tgtaccgaac aagtatttcc tatcattgga
    53641 ccgtcttcaa catctgatca aaacatcaga aatttggtaa atatcaatcc ttccaatcga
    53701 ggaatgggtg gacaagtcta tggttcagat ggcgtagcgc caaccttaac aggtgatgaa
    53761 ggaatcaaaa tcgcactgcc agcaagggat ggaatctctg tagcaggact attac
//
LOCUS       DADVXV010000009        52348 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.009, whole genome shotgun sequence.
ACCESSION   DADVXV010000009 DADVXV010000000
VERSION     DADVXV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.009"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(7..1581)
                     /locus_tag="KB969_000481"
     CDS             complement(7..1581)
                     /locus_tag="KB969_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6868495.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(1836..2345)
                     /gene="mreD"
                     /locus_tag="KB969_000482"
     CDS             complement(1836..2345)
                     /gene="mreD"
                     /locus_tag="KB969_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBB6868496.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(2349..3203)
                     /gene="mreC"
                     /locus_tag="KB969_000483"
     CDS             complement(2349..3203)
                     /gene="mreC"
                     /locus_tag="KB969_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBB6868497.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(3358..3996)
                     /locus_tag="KB969_000484"
     CDS             complement(3358..3996)
                     /locus_tag="KB969_000484"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBB6868498.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(3997..4647)
                     /locus_tag="KB969_000485"
     CDS             complement(3997..4647)
                     /locus_tag="KB969_000485"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBB6868499.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(4660..5559)
                     /gene="rsgA"
                     /locus_tag="KB969_000486"
     CDS             complement(4660..5559)
                     /gene="rsgA"
                     /locus_tag="KB969_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBB6868500.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(5724..7793)
                     /gene="pknB"
                     /locus_tag="KB969_000487"
     CDS             complement(5724..7793)
                     /gene="pknB"
                     /locus_tag="KB969_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBB6868501.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(7790..8530)
                     /locus_tag="KB969_000488"
     CDS             complement(7790..8530)
                     /locus_tag="KB969_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBB6868502.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(8543..9901)
                     /gene="rsmB"
                     /locus_tag="KB969_000489"
     CDS             complement(8543..9901)
                     /gene="rsmB"
                     /locus_tag="KB969_000489"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBB6868503.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(9901..10839)
                     /locus_tag="KB969_000490"
     CDS             complement(9901..10839)
                     /locus_tag="KB969_000490"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBB6868504.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(10832..11323)
                     /gene="def"
                     /locus_tag="KB969_000491"
     CDS             complement(10832..11323)
                     /gene="def"
                     /locus_tag="KB969_000491"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6868505.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(11338..13746)
                     /gene="priA"
                     /locus_tag="KB969_000492"
     CDS             complement(11338..13746)
                     /gene="priA"
                     /locus_tag="KB969_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBB6868506.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(13999..14304)
                     /locus_tag="KB969_000493"
     CDS             complement(13999..14304)
                     /locus_tag="KB969_000493"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6868507.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(14309..14923)
                     /gene="gmk"
                     /locus_tag="KB969_000494"
     CDS             complement(14309..14923)
                     /gene="gmk"
                     /locus_tag="KB969_000494"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBB6868508.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(15410..15694)
                     /locus_tag="KB969_000495"
     CDS             complement(15410..15694)
                     /locus_tag="KB969_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868509.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(15712..16602)
                     /locus_tag="KB969_000496"
     CDS             complement(15712..16602)
                     /locus_tag="KB969_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBB6868510.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(16622..16840)
                     /locus_tag="KB969_000497"
     CDS             complement(16622..16840)
                     /locus_tag="KB969_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBB6868511.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(16810..18510)
                     /locus_tag="KB969_000498"
     CDS             complement(16810..18510)
                     /locus_tag="KB969_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBB6868512.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            18777..19550
                     /locus_tag="KB969_000499"
     CDS             18777..19550
                     /locus_tag="KB969_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868513.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(19631..20200)
                     /gene="thiT"
                     /locus_tag="KB969_000500"
     CDS             complement(19631..20200)
                     /gene="thiT"
                     /locus_tag="KB969_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBB6868514.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(20266..20368)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(20374..21345)
                     /locus_tag="KB969_000501"
     CDS             complement(20374..21345)
                     /locus_tag="KB969_000501"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6868515.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(21439..22812)
                     /gene="glmU"
                     /locus_tag="KB969_000502"
     CDS             complement(21439..22812)
                     /gene="glmU"
                     /locus_tag="KB969_000502"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBB6868516.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(23315..24133)
                     /gene="purR"
                     /locus_tag="KB969_000503"
     CDS             complement(23315..24133)
                     /gene="purR"
                     /locus_tag="KB969_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBB6868517.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(24300..25124)
                     /locus_tag="KB969_000504"
     CDS             complement(24300..25124)
                     /locus_tag="KB969_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6868518.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(25097..25777)
                     /locus_tag="KB969_000505"
     CDS             complement(25097..25777)
                     /locus_tag="KB969_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6868519.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(25800..26738)
                     /locus_tag="KB969_000506"
     CDS             complement(25800..26738)
                     /locus_tag="KB969_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBB6868520.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(26983..27846)
                     /locus_tag="KB969_000507"
     CDS             complement(26983..27846)
                     /locus_tag="KB969_000507"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBB6868521.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(27988..30561)
                     /gene="mprF"
                     /locus_tag="KB969_000508"
     CDS             complement(27988..30561)
                     /gene="mprF"
                     /locus_tag="KB969_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBB6868522.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            30702..31508
                     /gene="proC"
                     /locus_tag="KB969_000509"
     CDS             30702..31508
                     /gene="proC"
                     /locus_tag="KB969_000509"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBB6868523.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(31587..33143)
                     /gene="rny"
                     /locus_tag="KB969_000510"
     CDS             complement(31587..33143)
                     /gene="rny"
                     /locus_tag="KB969_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBB6868524.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(33554..34603)
                     /gene="recA"
                     /locus_tag="KB969_000511"
     CDS             complement(33554..34603)
                     /gene="recA"
                     /locus_tag="KB969_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBB6868525.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(34712..35953)
                     /locus_tag="KB969_000512"
     CDS             complement(34712..35953)
                     /locus_tag="KB969_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBB6868526.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(36193..36771)
                     /gene="pgsA"
                     /locus_tag="KB969_000513"
     CDS             complement(36193..36771)
                     /gene="pgsA"
                     /locus_tag="KB969_000513"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBB6868527.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(36980..37903)
                     /locus_tag="KB969_000514"
     CDS             complement(36980..37903)
                     /locus_tag="KB969_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6868528.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(38642..39928)
                     /locus_tag="KB969_000515"
     CDS             complement(38642..39928)
                     /locus_tag="KB969_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6868529.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(39921..41189)
                     /locus_tag="KB969_000516"
     CDS             complement(39921..41189)
                     /locus_tag="KB969_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBB6868530.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            41441..41902
                     /gene="mscL"
                     /locus_tag="KB969_000517"
     CDS             41441..41902
                     /gene="mscL"
                     /locus_tag="KB969_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBB6868531.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(41961..42407)
                     /locus_tag="KB969_000518"
     CDS             complement(41961..42407)
                     /locus_tag="KB969_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868532.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(42500..42745)
                     /locus_tag="KB969_000519"
     CDS             complement(42500..42745)
                     /locus_tag="KB969_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBB6868533.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(42860..43438)
                     /locus_tag="KB969_000520"
     CDS             complement(42860..43438)
                     /locus_tag="KB969_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6868534.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(43515..44045)
                     /locus_tag="KB969_000521"
     CDS             complement(43515..44045)
                     /locus_tag="KB969_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBB6868535.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(44049..44909)
                     /gene="rlmB"
                     /locus_tag="KB969_000522"
     CDS             complement(44049..44909)
                     /gene="rlmB"
                     /locus_tag="KB969_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBB6868536.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(44902..45297)
                     /locus_tag="KB969_000523"
     CDS             complement(44902..45297)
                     /locus_tag="KB969_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBB6868537.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(45294..46706)
                     /locus_tag="KB969_000524"
     CDS             complement(45294..46706)
                     /locus_tag="KB969_000524"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBB6868538.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(46703..47239)
                     /gene="cysE"
                     /locus_tag="KB969_000525"
     CDS             complement(46703..47239)
                     /gene="cysE"
                     /locus_tag="KB969_000525"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBB6868539.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(47325..47564)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(47561..49021)
                     /locus_tag="KB969_000526"
     CDS             complement(47561..49021)
                     /locus_tag="KB969_000526"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBB6868540.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(49191..50348)
                     /locus_tag="KB969_000527"
     CDS             complement(49191..50348)
                     /locus_tag="KB969_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBB6868541.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(50382..51752)
                     /gene="radA"
                     /locus_tag="KB969_000528"
     CDS             complement(50382..51752)
                     /gene="radA"
                     /locus_tag="KB969_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBB6868542.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(51815..52342)
                     /locus_tag="KB969_000529"
     CDS             complement(51815..52342)
                     /locus_tag="KB969_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBB6868543.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT        14205 a        11400 c         9369 g        17374 t
ORIGIN      
        1 tcattcttac atgctgacag caaagtcagg ggcaaaccat tgaactgaac caacttttac
       61 gctttcgcct ggttgaggag catggatata ttgtcctccg cctaaagcaa tcgctacgtg
      121 gtaagttccg ccttgtgacc cccagaataa caagtctcca gcttttgctt gagaaactga
      181 aatttttgtt ccagctgatt cttgaggaac tgtccaacca ccgatgtcac gaccagttac
      241 ttgcatgtaa acatagcgtg tgaaccctga gcagtcaaag ccacttggat ctttaccgcc
      301 ccaaacatat ggagtaccaa tatatttgta agcttctgct acgattgctg caccattcac
      361 acttccagaa ggagctggag caggtgttac aggttttggt tgttcaggtg ttggtgttgg
      421 cgttggagcc ggagtactac ttcctgtgcc gtttcctgta tcaacacttt gatctgttga
      481 tggtgttgta ggcgcaggtg ttgttgattc ttctgttgtt gaagattcag gcactgttgt
      541 tgattcttct gttgctgaag attcaggcac tgttgttgat tcttctgttg ctgaagattc
      601 aggcgctgtt gttgattctt ctgttgctga agattcaggc gctgttgatt cttctgttga
      661 agattcaggt gttgttgatt cttctgttgc tgaagattgt gtagctgatg atgattcttc
      721 agtcattgaa gattgtgtag ctgatgattc ttctgttgct gagctttgtg cagtagatga
      781 agcttgagta gcttgtgctt cagcctctgc ttgttcgcgt gcttcttttt cagctttttc
      841 ttgtgcagct tgttgacgag cttgttctgc tagacgttgt tgttcacgaa tacgagcttg
      901 ctctgcttca gcttctgctt tttgacggtt caagtcagct ttcttgtctt cagcagttgc
      961 ttgttcagca gctaatgaag ttttcagtac gttcaaatca gcttgtttag ataaaagatc
     1021 gcctttttga gattccaaag cagcttggtt ttcagctaat tcttttagtt tagcatcgtt
     1081 ttcagctttt ttgtcttcta cagctttttt atcttgtttt tgttgttcca tcaagtcgtt
     1141 gtttgctttt accatcgttg tcattgcttg aacgcgtcca atagcatctg ctaatgaatc
     1201 agcattcaat acagcatcga tgtagtttga gcttgtgttg cttacttgtg cttcgcgtgc
     1261 ttgtttttgg attgtatctt cacgtttttc aatacgttct tgtaaatctg caatgtcttt
     1321 tactaattgt gcagattctt gacgcaatgt atcttgtttt gctaataggt cttgtgcttg
     1381 tgtgttgatt tcagaaactt ggctttctaa ggcatcgatt tgtgattgtg catctgcttg
     1441 ttgatttttc aagtctgcaa tcttttgatc ttgctgttgt atctgagaat caaaatcgtc
     1501 cgccgcggca gcgatcggtg atgctacggc agtcaaggtc attgaacata ccattactgc
     1561 tgatattaaa ctctttttca ctcttcattc ctccgactgg cttaatttaa taaatatcta
     1621 aatatattta agtctttctt aacgatataa aaattgtacc atagcagtgt gtcaacgata
     1681 taatagttat gttacaaaaa tgtttcaaaa caacttttaa aaatgacaaa actgttcgtt
     1741 tcagaaaatg atcatgaaaa agccgcgtta agtctagcat ttcttaagat aacaacgatt
     1801 ctttttcgct ttcgacctaa aaataaaaaa agaaattatt catcactgaa taatttctta
     1861 aagggaaaaa tgaataatac aaatataatc atgttcaaca gcagtgtagg tcctaaaaac
     1921 cttgtaataa aatacgtgtt atttactact gctaatttaa aaatcaactg gaccaccatc
     1981 gtaaacaatt cataacccgt gacaaagatg atcatactga aaaattcagt aaagatgttg
     2041 acatggataa cgtctttcat tacatacatc aaccatacaa ttaaagggag agctactgca
     2101 tagataccga taacgccaat atagtaagcg tcatagatag ccccgagaac aatcgtggta
     2161 atcagtaaat aacgtttttc aaacgccata ctgcaacata ataatgccaa tatcagaaag
     2221 tgggcatttg acatataggt gcctttcgac cactccccta gcattcttgt taaatgacca
     2281 tctatcaaca tcaaaaagaa caaaacgatt ggcagatagt acttcattgt ttctttcttc
     2341 aacatggact aatcctccgc tagccgttgg acaatcgtca caactgacac gtcatacatt
     2401 tctgcataag gtttcacata aacttcccga tccagcccat aactatctgg tttcgtttta
     2461 ataaccgtac cgatcggcaa gttagctgga gaattccctc caagaccgga tgtctggaca
     2521 acatcccctt ctttgatatc cgtatcacca gttaattggg tcaccactaa ggcatggagc
     2581 ttttcatcat agtttttaag caaaccaaac gcttcgccat tagccgaaga tacccgtact
     2641 ggaaaatgat tggagctttc attagaggat gacagtaatt cgattttaga cgaagccgta
     2701 ttgacctcga tcactcggcc aatcaatcct ttttgcgaca tgactgccat atttgcttcg
     2761 ataccgtctt tagaaccctt gtctacgatc agcatgtcct gccaactgtc aggcgaacga
     2821 gtaatgacat ttgccgttac tttttcgtaa ctagtcagcg tctgattcaa ctcaagttct
     2881 tttttcaacg cttcgatttc tctctcgtaa ttcttgtttt gctgtgaaac gtcatcatag
     2941 ctatcgattt tttcttttag ccgctcattt tcggcataag ttgaaaaaag attatggaca
     3001 gaatctactc catttcgtac ccaccgtact ggggcagaga ttgttttatc aaccattgca
     3061 acactgtcat taacgatgga ttggaagaaa ttgggctttc cttcattcgc tcgctgcgca
     3121 gcggtcacac ttagtatcgt caccacgatg ataacaataa ccaaggtaat aataatattt
     3181 ttattaggat tgaacttctt cacaaagaca cctcgaatta attagactct tgtgttcaat
     3241 tttatcacta aatgccgtga aacaaaaggt aagttgctcc tcttaagctt ttttttagca
     3301 aataatagat tctgtcattt ttagcctgaa agacaaattt ttttatttgt ttatggatca
     3361 atctttgctt tgaataactg caatcatacc atctgaaaaa gaaaattctg cggtatctga
     3421 aagaaattcg ttacttgcat aagatgtcgg atattctact tctttatttt ccaatacata
     3481 cttgctgcct tttaatgtaa gattcgagac gggagtcaag cagcaataag ctaaatactt
     3541 catatctggt atctgtctta ctatatgctc tccaggcaaa taataagaca aataattttg
     3601 acaatctctg ataataagct gatgggcaaa gggtttgaag cgaggttcca tacctaacca
     3661 gagattggct aaaagatgat ccaatcttcc gcccgtagct ccaatcaaag tgacttccgc
     3721 ttgcgggtaa cgttcaaatg tttttaagat acctaactgt gtatctgtat cgtctttttc
     3781 tgcaggggaa cgggtatact ctttggcttt tgcaaatact tccttctgct cttcgttcga
     3841 caatgaatca aaatcaccca ctgccagatc tactgggtag cctgcttgaa gcaggtacag
     3901 cgcaccacgg tctatcccga cataggcatc gtatttggac agcagagact gcggccagtt
     3961 ttgcggatta cctccagcag ctaataaaat tttcatttag tctaatgcct cttttaatcg
     4021 ttcgatttgt ccgactggat tttcggctcc atagatatat gatcctgcaa cgaagacatc
     4081 cgcccctgca tctttacaga tttttgctgt ttctggaacg attccgccat ctacttcgat
     4141 tgcataagtc caattgttct ctctacgtag atcagcgagt tccgtaattt tttctactgt
     4201 ttcttcaata aagctttgtc cgccgaaccc aggattgaca gtcatgacta gtacttgatc
     4261 agccaaaggc aaaacatgtt tgatcatgga gactggtgtt cctggattga taactactcc
     4321 agctttaact cctaagcttt ttgtcatttg aagtgcccga tgaatatgag gagttgcttc
     4381 gacgtggaca gtaatgatat ctgctccagc ttttgcaaat gctggaatgt agttttctgg
     4441 atcaacgatc atcagatgga cgtctaacgg taatttagta acaggacgga ttgcctgaac
     4501 aatatttggc cctaatgtga tatttgggac aaatcggcca tccattacat ctacgtggat
     4561 gtaatctgcg cctccttttt ccactaactc aatgtctctt tgtaaattgg caaaatctgc
     4621 actcaaaatg gatggtgcta tcttcattct tgtttcctcc tattttcgtt taccttcttt
     4681 ttttgcatac attggttttc ttttttcgat ttcttgtaag aattgcaaat aattgtcgta
     4741 acgtgtctgt gcgataccac ctgtttctac tctatgtttt acttcgcagc caggttcttt
     4801 agcatgcatg cactctctaa atttgcaatg gacagaagct tctacaaatt caggaaattg
     4861 tctcggcagt tctcctgctt caattgtcaa aaagtcaatc gagctaaatc ctggtgtatc
     4921 tgctactaac ccgccataga taggaatcag ttccacatga cgtgttgtat gccgtcctct
     4981 tccaagtgca tcagaaatct ctcctgttgc taaattcagt tccggtgata tttgattcag
     5041 tagcgtcgat tttcctgctc cagactgacc cataaagacc gatagccgtt ctgggaagta
     5101 acggatcagt tctgtcgtat cacccgtatg attgggtaca atcaccggat agcctatttt
     5161 agtataggtt tgcttgatct cttcgatttt ttctgggtcg tctgacaagt cggtctttgt
     5221 caaaaaaata atcggttcga tcgactcgta ttccaaggta actagaaagc ggtcaagtag
     5281 attataagaa aatgcaggct ctacgatact tgtgacaatg attccaagat caacatttgt
     5341 gactggtggg cgaactaatt gattttttct cggcaagatt tccagaagat agccgtctgt
     5401 ttgattttca ctctcaaaga tcacctgatc tccgacaagc ggcgtgattt tccgattccg
     5461 gaaatttcct cttcctcttg tttgataggt ctctccgttt gcgtatacat agtaaaaacc
     5521 gctgattgct tttctgattt gtcctttgat aagtgccacc tccgtttttg tttattttac
     5581 catacgaaga ggaaagtagg tgttattcca tgcaaacttc tcaaagtata tggcttgaaa
     5641 attgatcaaa agagatagaa acacaaaaaa gagaatgcaa caaatcaatg tcgcattccc
     5701 ttctgatata ttttattcag cacttatttt gaactttctg aggtgctagc tgatgaactt
     5761 gtggagctgg aagattcttc ttttgaagag ttgcttgtgc tactggagct acttgagctg
     5821 ctagaactgt ctgaagagtc tttttcagaa ctagaagacg ctggatctgg tcctttagag
     5881 taaattacgt tcacaaccat tcctttggta attgtcgttc ctgcccctgg tactgtacga
     5941 atcactttat ctttatccac cgtgtttgaa tattcggaag tctcatgccc gatatattct
     6001 gcaccgacac tagctaaata actttgtgct tcgctttttg tatagccgga gatatcattc
     6061 aatttaggct ctgttccttg gcttacgaca aaattgatgt aagtttcttc tgctacaact
     6121 tcacccgagg ctggatcctg actgatgatc gaacctgatg gtacagtgtc gctatagtca
     6181 taagtagcac taatattatt gatattgaat ccttgtgtaa caagccaatt acgaacagtt
     6241 tcgtagtttt ctcctacatg actactcaaa gtcactgttt ctggtccttt gctgactgtg
     6301 aaagtaatcg tgtctgtttt aggatcgact tctgtatctt ctgatggaga ttgcgaaatg
     6361 atcattccgc tttctacctc tgaactgaat tcctcttctt tttgaatcaa gtcagcagaa
     6421 aaccctaatt ctttcaaact tgcttcggca tcttcataac ttttaccact gtaatcatct
     6481 aatttgattt ttttcgtgcc gctactaata tacagagtga cttcgcgttt ttgcttgact
     6541 gtcgttcccg ctgccgggtc tgtcttcact acattacctt cttcgatttt gtcatctgca
     6601 atttcttctg tttttgttgc tacttctaat ttcgcttttg cgagtgtttc tctagcagaa
     6661 gcttcagaaa gatcagaaac atcaggaaca acaacttctc ctcgcccgcc agaagcaaag
     6721 aatacagctg ttccgattcc taaaacagca agaatagcta ataggatcag ccaccatttt
     6781 ttctgtcctt tctttttagg atcaggcaga acttcttcct cctctggtaa ggtttcgttt
     6841 tctggcttgt cttttggcag aggcatagat ttgaatgaat caggcattgg tgcatcttcc
     6901 gtaaggggtg tgataacttt tgtttcatta tccatcacat gaggctgcca tttttcttcg
     6961 tttgcacgag ctggtgataa tactgtagaa agatcatcag acatttcctc ggctgactta
     7021 taacggtctg caggttcttt agccgttgcc cgtaaaatca cgttttccag tgcttgtggc
     7081 acatttggat caagtgcttt tatagatgga agatcatctt gaaaatgttt taaagcaatt
     7141 gttacagcag attcaccatc aaacggtacg ctacccgtca acatctcata aaggatgatc
     7201 cctaaagcat aaatatctga ctgcttcgtt gccatacttc ctctggcctg ctcaggggac
     7261 agataatgaa cagatcctag catcgtattc gtctgcgtga tcgatgtttc agataaagcg
     7321 atagcaatcc cgaaatccgt gatttttaca acaccttcat tatcgatcag tacgttttgg
     7381 ggtttcaaat ctcggtggat gatttgatgg ttatgagcta aagaaatagc agaaaggatc
     7441 tgctgcataa tatttactgc tgtttcataa ggaacaggat aatgtgtttg gatatatcgt
     7501 ttcaagtcca ttcctttgac gtattccatc accagatact gcatgttgtc ttcttcacca
     7561 acatcgtaaa cactaacaat gtttggatga acgagttctg ttgctgctaa agcttctctc
     7621 tgaaatcgtc gaatcgcagt ctggtcattt tgaaagtcaa atcgtaagac tttaactgct
     7681 acatcacgat ccaagattaa atcgtgcgcc aaaaatacat ttgccatacc accgctaccg
     7741 atatttccag tgatttgata acggccattt aattttttgc ccaactcgat catacactgt
     7801 cctccttata ttcgataaga agaacggtga tattatccgc tccgcctgct tcattggcac
     7861 gatcaatcag ctcagttact ttatgagaca atgggccttc ttgattgatg atcgttccta
     7921 tttcttcttc agacagcatg ttcgtcaagc catctgaaca taacagcagt cgatctttta
     7981 gttgccaaag atgagtagaa acatctactt cgactgttcc aggcatgccg acagaacgtg
     8041 ttaaaatatt tttccttgga tggttcactg ccatttcttc gctgatttct cctgatttga
     8101 ctagttcatt gactaaagaa tgatcctccg tcaattgcat gattttatct tcacgaatca
     8161 aataagctct gctatcccca acattggcaa tcgtgaacca gtcatctgac agagcggccg
     8221 ctacgattgt tgttcccata ccgttatatt ccggctgttc ttgtccacgc tgataaatca
     8281 gcatattttc ttcttgaatc gattgaatga accattgggc gattttttca tcgtcaacag
     8341 cttcttgttt ttcccaagct tcgcctagat tcgttaccgc catctgactg gcaatgtctc
     8401 cggcacgatg accacccatc ccgtctgcta atacagcaag cttgagacct gaacggctgg
     8461 taaatacact ggcatagtct tgatttgtgt tacgtcgtct tcctacatct gattgatatt
     8521 caatctgcat tttttcacct cattactttt tgcgcaaaca acaaatgaaa aatccatctg
     8581 tgtaaaactg atgcggatac aaagtcaaca ttttctcttc gattgatgat tgtagcatag
     8641 gattggtcaa aacatcaatc ctctcaaaat cagggtgtct ttccaagaaa gcagaaacaa
     8701 cgtcttggtt ttcttctttt aagatcgtac aagtgctata agtcagaata ccggaagact
     8761 ttaaagttgg tgcgcagctt tctaaaattt ccaattggat ttttggtaaa ttcgctaatt
     8821 catccggctg ttttttataa cgaatatctg gttttcgccg aagcagccca agacctgaac
     8881 aaggcgcgtc tactaaaatc cgatcaaact gctctgcttc gaactgttta ctgacttctc
     8941 tagcatccat cttttgagcg tagacagcag aagagacacc tagacgtgct gcattatctt
     9001 caatgagttt gactttgtgt tcgtgtacat ctaaagcgac cacttctcca ccgcatgacg
     9061 gatctaaaaa agaagcaata tgcgtcgtct tacctccggg tgctgcacag gcatctaaga
     9121 catgatgttc aggctcgatt tgcatagacg gcgctacaag catcgaactt tcatcttgga
     9181 tcgtcatgac gccatcgtgg aacaatgagc tagaagctaa atgccctttt ttcgctacta
     9241 taccgtatgg actgacttgg cttttttcag ctgtgatctc ttcttcttgc aaaacagtga
     9301 tggcctgatc tctggaaagt cggcgtgtat ctactcgggc actagcatgg ctaggctgat
     9361 atagcgataa accgagcttt tcagtttctt cgtatccgat ttgatccacc agtcgtttcg
     9421 tcatccatag aggcaggctg attttgacag aaagtctttc gataggatca gcaatgcctt
     9481 gcagatctgg tgctccttga cgctgataat tcctcaagac accatttaca aatttccctg
     9541 tcccaggatt tccttttact tttgcgattt cgaccgcctc gtttaaaata gcatgtgcag
     9601 ggactttatc taaaaattct aattggtata cagaaagata aagaagcatc ttgacccagt
     9661 catccacttt ttttgcttta gcgatcaatg gtgcaacgta aaattccaat agtcgctgat
     9721 ggctaatcgt accatagatc aattctgtaa ataaacccac atctttttga tttagctcgc
     9781 tttgtttgat catctcattc aacaaaagat tcgagtaggc gccacccttg ttcactcgct
     9841 ctaatgtcag taatgccata tatcgtactg attttttcat ttttttaggg atttttttca
     9901 ttatttcacc tgctgaccaa tctgaacttg ctgaccgctt ccgttaagga aatcatgtac
     9961 ggcctgtttt cctttaccag ctggctgtaa ttcattgatg gctaagacgg tctgtttacc
    10021 gcaagcaatc catagatttt ttttgtcttt ccggatgatc gtaccaggtg ctttgtctgt
    10081 agtttctgcc aatacttcaa ccgataataa tttccagcgt atgccctcat aggtcgtgaa
    10141 tgcaattggc caaggacgca ttccgcgtac ttggttgtca atttcttctg cagttttatg
    10201 ccaatcgatt gcttcttgtt cccgtgtgat gtttggcgaa aaagttgctt ctgactcgtc
    10261 ttgaggtact ggtttttgtc catccaaaat attgggcaat gtttctagca atagctttct
    10321 tcctaaaagg ctaagctttt caaacatcgt ccctacatca tcttgtttag tgattggtat
    10381 gctttcttgc gcatagattc cgcctgcatc catttttttg atcatttcca tgatcgttac
    10441 accagtttct ttctccccat tcatgatggc ataatgaaca ggcgcacctc cccgatattt
    10501 aggaagtaaa gaagcatgga cattgattgc ccctaatttt ggtacttgca ataacttttc
    10561 aggcaagaat tggccaaatg ccgcagtgac gatcacatca ggcaccaatt caatgatttc
    10621 ttccatttct ggcgaaccgg agattttctc tggctgcagc acacggatac cgtgcttcag
    10681 agccgctttt tttaccggtg tcggcgtaat tactcgtttc cgcccaactg gacggtcggg
    10741 ctgtgttacc actgcctgga tctcgtaacc tgattctatc agcccttcaa gaatcggcac
    10801 agaaaaagca ggtgtgccca taaatactag cttagtcatc aagatgttcc tccatatatt
    10861 cttcaagttc ttcttccggg atctgctgta tcattttctc aatgaacaag ataccgtcta
    10921 agtgatcgat ttcatgctgg aaggcacggg ctaaatagcc aaaagccgtc acttctatct
    10981 cttctccgtc tcgatcataa taacgcacgg tcacttcatc tgctcgcttg accgttccat
    11041 agacatgcgg aatactgaga caaccttcta cgtcaaggct ttcacctttt gcttcgatga
    11101 tttctgggtt aatcagttca aatttctcgc cttcatctac ttcgatcaca gcaattctct
    11161 tgttttgtcc tacttgagga gcagcgatcc ctattccgtc attcgcaatc attgtctcat
    11221 ataaattgtc taataaagcg attgtctcgt ccgtgattac atcgattggc tgagcagttc
    11281 tttttaattt atcattaggg tggatcaata taggatagcg cataatttgg ccctttctta
    11341 aataaagttt aatggttcgt tgtcaattgc cacaaaaaga ccttgtcgct gttctttctg
    11401 gcttccattc aaaatttcat ccaaaacatg aggaagattc ggttcatgtt tatatttgat
    11461 gattagttga taataatatc ggtttttcac tctcaaaatc atgctgggcg ttggccctaa
    11521 tagcaagctt tgagggctta acacttcttt tagctgattg gcaatctgaa agattttctt
    11581 tgccgctact tgttcttcag gatggctggc ggttattttc acagtaaagt aataaggagg
    11641 atagcctcca cgatgccgta catgcatttc ctgctgataa aactgctcat aattttgttt
    11701 tttagccaat tctatggcgt aatgttgagg attgaatgtt tggatcacga cttcgcctgc
    11761 tttttccgct cgccctgctc gtcctgaaac ttgggtaagc aattggaatg tatgctcact
    11821 agaacgaaaa tccggtaaat tcagggaggt atcagcattc aacaccccaa ctaatgtcac
    11881 ttctggaaag tccaaacctt tagcaatcat ttgtgtccct aataatatat ctgcttcttt
    11941 tgcaccgaat ttttgtaaaa tctgttcgtg tgcccctttt cttcgagtgg tatctacatc
    12001 catacgcaaa atcctagctt gcggataaag ttctcggagt tcctcttcta ctttttgagt
    12061 acctgttcca tagtagcgga ttttattgcc gccacaatta ggacagcgat tgggaatagg
    12121 ttcttcatgt ccgcaataat ggcagcgcat tgaacgtgta tccatatgca gtgtaagaga
    12181 gatatcgcaa ttaggacatg gaagaacaaa tccacagtcc ctacacatca caaaagacga
    12241 atatcctcga cgattgagca gtaggacagt ttgttctttt ttgtctaatc gattttgtat
    12301 tttttcctgc aaattagcag aaaaagtaga ggtccgatga ttctgaaact cttcacgcat
    12361 atctacgatc tcaatagctg gaagctgtgc agctgctttg gctcggtggt ttaactgcaa
    12421 taactgataa acgccttttt gagctcgtgc tcttgattct aaagagggcg tcgcgcttcc
    12481 tagaactatt gggcaatgat gatatttact gcgccaaatt gctagatctc tcgcatgata
    12541 acgcggtgtc tcatcttgtt tgtaacttga ttcatgttct tcatcgataa tgatcagccc
    12601 gatatttttc agcggggcaa aaatagcaga tcgtgcgcct actactactt gcgcttcttc
    12661 ccgctcaatc ttgcgccatt catcatattt ttcaccttgg gaaagtccgc tatgtaagac
    12721 cgcaactgat tctccgaagc gtcctttgaa tcgctcgacc atttgcggag tcaatgcgat
    12781 ttcaggcact aacataatag ccgttttatt ttctgacaaa acatcagcga ttgcctgaag
    12841 atatacttct gttttcccgc tgccagtgat tccctccagc aaaaagacct gatctttttg
    12901 ctgctgacct gctgtgatga tttgttcgac agcatttttt tgttctgcat tcagttccaa
    12961 tgccgtcgtt tggtcaaata ctcggtcttt ataagggtcg cgataacgtt ctgattctat
    13021 aaactccagc cagccctttt cttttccttg attcaagaca gcagtactga ttcctttatt
    13081 tttgaaataa gcaattggtt cttcttggct cagttcagat aaacacaaaa gaagttcttt
    13141 ttgtttcttg gcattttgcc gtaattttgc ccattcttct tcgatttgct tttcagttaa
    13201 caaagaacgg accaaacgaa tcgtttttac tttatttcgt gtatggactt catatttgat
    13261 atctactaat tgctcttggc gccagcgaat caattgagaa aggctgcctt cttcttctgc
    13321 ttccttccag gaaatcactt ctcgctgatc aaacaatacc tgaacttctg gtgtgtctgc
    13381 caaaggatag atcaatttat catattctgc tttcatcaca ctcggaagca tcgtttgtag
    13441 acaagtgatt ttgaatgcgt aagtaatttt tttcatataa tcagctaatg aaagtaattc
    13501 ttcattgacc accggagcaa ggtctagcaa acgaataact gccttcaaag atggattagc
    13561 tgattcttct gatttttgga tagccataac aaatccttgg acatgacgat tgccattacc
    13621 aaaagggact tctactcgca tcccgacttg caaagctgtt tccatttcag agggaaccaa
    13681 ataagtgaat ggctgatcgg tctgcatagt aggtacgtcc acaatgactt cagctgttaa
    13741 tgtcatggtt cgtttcctcc tttttttgtc ttttcttatc aagcgacaaa aagttccttg
    13801 cctattttac tagagatcga tggatttgtc ttatcttctg ccaaatccta acaaaaaatt
    13861 aacagcagat aagaaaaaaa agaactgtgt caaaaagttc agacacagcc ttttctacca
    13921 gacaataagt ggcgaatgtt tgaaaaggaa acagctgggt ttgcttttct ttttagatgt
    13981 tcgctctatt tttctttatt acattttttg ctcttcacgg atacgtgatt ccaattcgtg
    14041 ttgttcacgc tctttttgtg cttgacgttc ctcttcttcc atcttcaaac gttcacgttt
    14101 taattcagga tgtggatcat tgactacatt tcctgcatcg atttcttcta aagcttgacc
    14161 gacgcttttt actgaatcaa aagaatctag agtaggctgt gcacttgcat ccaattcatg
    14221 cgcgcgttta cttgctaaaa tcactagaga atattttgaa tttacacgat ctaatagtga
    14281 gtcaattgaa ggttttaaca tcataagact acatctcctt taacatttta atatatttac
    14341 cgattacgcg atctactcga aaatgttcac tggcaataat gtttttgatt cgttcaactg
    14401 ctagcggcac ttcatcattt acaacagcat agtcgtaaag agccatcatt tcgatttctt
    14461 cttttgcaac tttcattcgt ttttcgatta cttcatctgc atctgttcct cggcctacga
    14521 tccgtgattt taattccgct aaatctggcg gagtcaaaaa gatgaataca ccatcgggca
    14581 ctttttcttt gacttgtttt gctccttgga cttcaatctc caagaaaaca tcttttcctt
    14641 catccaatgt cttgttgaca tatgacaaag gagttccata ataattcccg acatattctg
    14701 cgtattccag catctctcca gcttcgatca ttgattcaaa ctcttctttg cttcggaaga
    14761 aataatcaac gccttcgacc tccccttcac gcattttacg ggtagtcatt gagatcgaat
    14821 actgaaaatc attatcctca ctctcaaaaa ttgcttttcg tactgtgcct tttcctacac
    14881 cggatggacc agacaacacg attaataatc cacgctctga catgacgacg tcctttcaac
    14941 tagtcttttt gtacttatcg tttattttgc actttttttc tgcaactttc aaggttatct
    15001 ttaattatag ctagaaattg gtaaaaaagc taccctgtac caagaggtcg taaaaaagct
    15061 gtcctgcatc aagtaataag aacagccaaa cataaacagc ttctcatgtt tttcgtttgg
    15121 ttggggttat tatcgcagat gcaagctttt gaacgccgtg tataagaggt cgtgaagaag
    15181 ccgattagtt tcgagtatga agaaaaattt tgtgaaaata gtttctcaca tttttgcata
    15241 aatttggctt aataccgaga aaatggtttt tgaacatcac ttattcaaaa taaaaaaaga
    15301 ttgtgacacg aattttgtca caacctttaa atgtattcct agagcaaaga agctaagcga
    15361 agaaatccaa ttctgtttat ttattgtatt tctttgttca gcatccttgc taaaagccca
    15421 tattggacaa agtattcact acacccatga tctcatcttt tcgagaacgt gctttttctg
    15481 tcggatcttc tacctcttct gtgtcaattc gaacaataaa tttccgattc atcgtcacgt
    15541 aagcaccgtc gttgatcaaa ataaacagtt cgttctcatt atagtctgca caggcatctt
    15601 tccatacgtc aaagccgttt ttttcagaag ggatatcccg tttaaccaca gtttttccac
    15661 ttaattcgtg gaacgttacg tcataatatt tcattatctc tacctctttc gtcattcaat
    15721 attttgtact tgttctctga ttttttctaa gatcgtctta gactggacga cttgattttt
    15781 aatttcgatt gcatttgatt tggaaccgat cgtgttgatt tcccgattca tttcttggat
    15841 caggaaatct aattcccgac ctacaggaca ttgtgcttcg ataagttcat ctagtttttg
    15901 tacatggatc gccagacgat ccagttcctc gtgaatatct ccgcgttcca acaagatggc
    15961 tagctccgtc aacaaccgtt gctcatcgac tttcgctcca agaaattcct ccagcttttt
    16021 ttgatacctt atttgaaatt ccttttcata gatttctaca aaactatcga gtttttttag
    16081 tacttctttg aattcttcag tattcttttt caacactaaa gctaaagctt gaccttcttt
    16141 ttctcgactc gcctcaatag aatcaagtgc gcttttcaat gtatctagag ctaactgtgc
    16201 caattcttcc atgctctctt ccggtttttc ttctaccgtt acgaagtttt cgtccagcac
    16261 gaagcgttcc gccatccgac taattgacac ttgattttga ctaccgtatc gttgttgaat
    16321 tccgtctgtc aattgagtga taagtgaatc aatcaattcc cagttgatga cgatctgttt
    16381 ttcgtttttg ccaatataag ctagattcac aaatacttcg attcgaccgc ggcttaactg
    16441 ctgtttaata agctgacgaa aatcgttttc aacaaagttc aggattttag gacttcgtat
    16501 ttgaacatct agaaaacgct ggttgacact ttttatttca atatctaact gatacgcttt
    16561 tgtttcgcgg atggctttgc caaaaccagt catacttttc attcgacagg gtccttcctc
    16621 attacatatt ttctattgct ttttgcagtt gttcaaactc ttcgttcgtc aatgtcaggc
    16681 ctttccccat tttttcatgg tctggcgccc aatctcgaag atcgaatttt ggcgggcgac
    16741 cattccagct gactaggttc agttctttac gccacccctt gttgttttct gacaatatag
    16801 cgatttcttc tacgatttca tatgaaaatt cttgtgccat ggttgttcct ccttgagata
    16861 atataaatat aggatcagta atgtgtcaac tggttgctta agcaattcat gctgcaaacg
    16921 atccttgcgt tttccttgta gcagataatc aaaataaaca gttttcgtgc gctcattttg
    16981 tattttttgc tggtattttc gataccttcg ccattcttca gtacttaatt gaccaatttg
    17041 tgccaataaa tcatccggca tactttttat atcttgttgg cagatcattt gaatcatcat
    17101 gtctacttga tagatttcat tgggcagtaa aaaatgtttt tttgctaaaa gttctagcat
    17161 cgccaatccg catgtctctg gtacgaccct gttcttatat aaattacgca gtttttgcca
    17221 aaattttatg cttttgaaaa aagataattc taactgaatt tcttttgtta agtaagacaa
    17281 aaatcctcgc cagtatgttc ttgcaggttt aacagaatga aatgtatacc agttcccata
    17341 gtaatagcct aatcgttttt tcatttccag atagcctaat tgtaaattta attggttcct
    17401 ttggctatca aaaagcagaa agctgcctag tgtccacaat gtttgacatt tccaatggat
    17461 aaaaatgtct ggcatacgaa tttttttcgc tgggcctggc ccttgcacat ctacgacaaa
    17521 tgcctctgtt gctcctttgt taatcgcaat atcaataggt attttgttgc gatacccacc
    17581 gtctgcatat ttattttttc cgatctttcg ataagccata gcgggataaa atgaagcaga
    17641 ggcgagtatc caatctggta tttcttctgt ttttgtctgt tggatatcag tcactacttc
    17701 cgctagttct ggcagtttag tagacaccgt atataaacgt attttgggat tatgtttgag
    17761 taaggacaaa tccaaattgt ctttgaccat cttttccaat ggagcagaag aaaccccgcc
    17821 ttcaattagt gctgttttcg tcatttggcg tctttctcga tagaagcgtt cacgaaggtc
    17881 ttcaactgca gccatttctg gtaacgcaag cacttgtctt gtcgacagct ttttccataa
    17941 attcacagct tttttcatat ctccttgtaa aatcaatgcg ccgttcaacg cacctaccga
    18001 ggtacctgtg ataatctcaa agttgatatc atgttccttc agcgcctgcc acacaccaat
    18061 ctgataagca ccgtgcgctc ctcctccacc taaaacaagt gctgtatgat agaccagctt
    18121 tttatttaat tgtgtggttc cttgatagcc gtttttatga aaaatacgca accattcttc
    18181 tgatagagga gattgaaata aaaaacaaca gttttcttta ataaaaaaac gagcgcaagc
    18241 ttccatatac cgaaaaaatt ttttccattc aaaagtttca ccttcaatca acagattatt
    18301 aaaaataaca tctcctctac ttttagcaat agtaaaatag acggtatatt ttttcgatac
    18361 tgctttaaaa gcacattgct tttttgcaga acgccaaaaa gcgtctctac tttcttgatg
    18421 actttgaaaa aatggaaggg gttgttttgc ttgctggata ggcgaataca gcgacatttt
    18481 ctgtgaaaag taaacttttt ttatctccat cgcgctctcc tttttcttca agtataccag
    18541 tacgtcataa aaaggtcatg agtctcgtat tcgactttgt agattccata agaaaacaat
    18601 tcataaaacc tcctttaaat aaaaaaatac aaaaatcaca aaaattaatt gaaaatgaga
    18661 gtgttttcaa tgaaaacgtg attttgtaat ggaattttaa aataaaagaa acaagctttt
    18721 ttaatgcaaa tgttgtaaaa taaaagagat taagaggaaa taagaggagg aacatgatga
    18781 ctgagtcagt ttatgtacat attgatacca caagtaatgc tgttttaaca aaagggctga
    18841 ctgctactga ctttgcaaac agtatcgtgc attttcctca aaacttgctc ttgcttgatc
    18901 catctgcttc tgctggagaa tatgaatccc atacagggct gaaagtaatc cgtggtacag
    18961 aaaatattca gcgtttcttt tcctcttctc gtaacaggcg tggattcgat gaattgaagt
    19021 ggatcgactt tactgattta acgatgctga aagaattgac acctttagaa atttcagaat
    19081 tattatattt tggtcatatg aaaacacatc ttcattcgcc gtttttttat aaactacaga
    19141 ataattttgt atacttcgat cttaatgatc agctgaatcg gatttattat cgctatttag
    19201 atgaatttta taggattttt gctagtaaat taagttcgat cttgtcagat aagatcaatg
    19261 taaaaaaatc ttttttcaaa aaagaaacac ctgttgaaaa aatcagtgtg gaattattga
    19321 aagaaatgcg taatttgatg caggaaggga tcattttttc ttttgatcaa gttggtttga
    19381 tcgatggtaa atatcgtatc ccaatctatg tgattgaaga ttatatttgg aaattaaaag
    19441 gcacccggta tcgagaagag gaaatcatcg ctactttaat ctactctgtc accgatcgac
    19501 actggcaatt ggtagaagat gccgatcttt cttatctgcc attgaagtag atctatttct
    19561 tatcaaaaaa taaaaaggaa acaagaaact aggacatgat tctgtctcaa gtttcttgct
    19621 tcttttttat ttacagctcc tgtcgtttat ctggcacaaa aatcgaagga gtcgtttgtt
    19681 ggatccctaa taaaacgatg atcgttacaa tagctgtact caacccgctg gcaccattca
    19741 ttacgaaaga aaagagccaa ggattcatcc cccatagtgc atacgctccc cagaaaacca
    19801 ctcctgcaat aaaatgccaa aaatatctgg aaagtgcgcc aatcaatgca ccaaacacga
    19861 tgctttttct aatttgtttc gtattatcgt ctacatagcc tttttggaca tttgaagcca
    19921 tgagccctgc tgcgcctgca aaagtatagg caatcgggta ctcaatcaac acttgaacga
    19981 cacttaaata ataaacttgt cccaacggaa aatgtaggat gccccaaatg aaacctgcca
    20041 gcatccctgc ctttgtccct cttcttaacg caaaaagagt caatggaatc tgccctaatg
    20101 aaatagaaaa actgctgccg atctggatcg gaatcaacga caacaccatc gctaacgctg
    20161 caacaatcgt tccttctacc caaactctat tttttcccat aaaaaaactt cctcctttga
    20221 ataaaaaagt cacaaaggag gaagcagctt tcgaaaatag tcaaacagct gtttattcac
    20281 aattcctacg ctcgcataac cgatacaggt acgaagggtt tagaaataga ttcaatctca
    20341 gcccaattgg actccccttt gtgagtttat ttattattta ttttttgttt caaacaatgg
    20401 actaactggt ttgttttcat ggatacgttt gattgcatct cccattagtc cgccaacact
    20461 tacttcatcg attttgtcga ttttacgatc ttctggaaga tagatcgagt ctgtaacaac
    20521 tagacgctcg atagctgaat cttctattct ttgtaaagca gggccggata atactggatg
    20581 tgtacatgaa gcatacacac tagttgcacc agcttctttc aaagcattgg cagccaatgt
    20641 gatcgtacct gctgtatcga tcatatcatc gatcagtaca caagttttgc ctttgacttg
    20701 tccaatgata ttcattactt ctgcaacatt tgcttttgga cggcgtttgt ctatgatcgc
    20761 aatcggagat ttcaaaaatt ccgctaattt acgtgcccgt gtgacaccac catggtctgg
    20821 tgaaacaacg acaacatcat cgcctttgat tcctttttct aagaaataat tggcaataag
    20881 tggcgcaccc atcaaatgat cgactggaat atcaaagaaa ccttggattt ggactgcatg
    20941 aaggtccaaa gtcagcattc ttgttgcacc agctttttga atcatgtttg ctactaattt
    21001 cgctgtgatt ggttcccgtg cacgtgcttt acggtcttga cgcgcatagc cataataagg
    21061 catgactacg ttgattgttt ttgcacttgc tcgtttcagt gcgtcaatca tgatcagcaa
    21121 ctccatcaag ttatcattga ctgggctgct cgttgattga ataacataga catgcgatcc
    21181 acgaatactt tcttcaatgt ttacttgaat ttctccatca ctaaattgag taacagatga
    21241 ttttcctaac tcgacgccga ctgctgctgc aattttctct gctaatgggc gattggaatt
    21301 taacgcaaaa atttttaatc ttgggtcaaa gtaatgtttt gacatgggga cctccacttt
    21361 ctttttcaca actctagaat tctacctaat aaatagtagt catatttttt aaataaatca
    21421 agtgattttg caaaagtctt agtttagata agggagtttt tttgcatatc cttctttatt
    21481 gacttgtctt gctctcgcaa ttgccagcgc atattctgga atattgtctg taattgttga
    21541 cccggcagca atcgaactgt ttttagctac ctcgacaggt ccgatgatat tcgtgctaga
    21601 accaataaag ctgtggtcgc cgacagtcgt atgatgtttg ttctttccat catagttgac
    21661 gaagacaaca ccacatccga cattgatttc ttctcccagc gtagcatcac caacataagt
    21721 caagtgaccg actttagttc ctttgccgat ttgagcattt ttcacttcca caaagtttcc
    21781 gatatggacg ttttcgccaa tttcagcttt tggtcgtaaa tgtgcataag gtcccacatc
    21841 tgcatgtttc ttgacatggc tgctttcaat gactgagttt tcaatgacga cgtgatcctc
    21901 aatcctactg tctacgattt ttgaatgtga cccgatgaca caatcagaac caatgactgt
    21961 atttccttgg atttgtacac ctgcttcgat caatgtgtct ggaccgattt ctacgcctgc
    22021 atcgatgtat gtcgttgctg aatcgacaaa gcttacgcca ttgaccatat gcatctggtt
    22081 aattcgcttt ctcatgatct catttgcttt agctaacgcg atccgatcat tgactcccat
    22141 tgattcttca aaatcatccg tttgataagc agcaactgta tggccttctt cttttaagat
    22201 ttcgatgata tctgttagat agtattcacc ttgagcattg tttgttccaa ctttgcttaa
    22261 cgcatcgaac aaagcttcgt tgtcaaaaca gtaagttcct gtattgattt cttgtacaag
    22321 agcttcttct ggtgttgcat ctttttgttc cacgattttt tctacgatcc caatatggtc
    22381 acggatgatt cgtccatatc ctgttgggtt ttctgcttgt gccgtcaaga tcgttgcact
    22441 tgcatttttt ccttggtgat attcaaaaag attgttcagc gtttcagtag tcaataatgg
    22501 tgtatcgcca ctgataacta acgttgttcc tttttttcct tccaagaaag aagcagcttg
    22561 caaaacagca tgtcctgttc ccaattgttc tgcttgtaac gcatatttac tgcgttctcc
    22621 tagttgtgct ttaacttgtt ctgctccgtg tccaacgatc gtaatcactt catctggttt
    22681 cgtttcactg acccgattaa tgatatgttc taccataggt ttaccagaaa cgggatgtaa
    22741 aactttatat aattttgact tcatgcgggt acctttccct gccgccaaaa taattgcata
    22801 acgtgcgtcc aactgcgtca ctcctaaata tagtttgctg atttcagttt atcccagtat
    22861 acccattttt tcaacaaaac aagtgatttt cttttatccc agcgttttct ggataaaaaa
    22921 atagatagac cataacgggc ctatctattt ggtaaccggt gctctcctgc caactcctcg
    22981 gtcacaagtc acactactca taaaacatga aaagctgttt tttgaaatcg tttcttgtga
    23041 cttagagtta aacggtaggc ttacaacctc ttcattaaac gtttttcaat cagctgacct
    23101 tcggtattag ctcaataaac ggcaaaatat gaggagcaat ttttccgttt attgagctaa
    23161 tactcaggac aggacgctga tttcacaacc tctagataaa cggtgttcaa aagccagttt
    23221 ctcggtatta agccaaattt atgaaaaaat gtggaaagcc attttcacaa aatttttctt
    23281 actactcgaa actaagcggc tttttcacaa cctcttattc tgaaaaataa tttcctggca
    23341 caaccgtaat atttttcgtt tgagtatcta catctttgac ataaagcagt gacgtataat
    23401 catcgatggc gcgatgaccg ttgaattttg attcggcaaa tacagtgatg ccaacaagtt
    23461 ctgattcgaa ttcttcaatc aagctcttca ttccgttgac tgttccgccg cctttcatga
    23521 aatcatccac tacaaggaca cgtgaaccac gtttcaaact tctcttagac agttccatct
    23581 tttcaattct ttcagaagat ccagacacat agttgacact tactgttgat ccttctgtta
    23641 tttttgagtc ccggcgtaca ataacgaatg gcgcattcag ataataggac acagcttggg
    23701 caataggtac gccttttgtg gctacagtca ttacagcatc gattttttca ccaaggtatt
    23761 tagaagcaat gattcttcca acttgacgca gcagttcagg ttctcctaac aaatcagaga
    23821 gataaacata tcctcctgga agcagacggt cttgttctga tagacgttct gctagagatt
    23881 caatatattt tttcgcctct tcatatgaaa tttcagggat gaacaataca ccacctgcag
    23941 cacccgggat tgtttccaag gttccatacc ctcgttcttt aaatgttttc ttgatgattc
    24001 ccaaatcttc actgatagaa gatttagcag attcataacg ttcggcaaag cttgttaagg
    24061 aaatcaattc atgcgggtga ttcaataaat actgtgtcat gtcaactaga cgttcactgc
    24121 gacgtacttt cacctattcc aactcctttt aagaaatttt atcgttttac attatataag
    24181 tttttcttca aaaattcgag cattttatga aaaaataaga aaatagttcg gtatttatta
    24241 aaataaaaag aagcctataa aaaatttttc gtttttataa ggcttctttt ctttataatt
    24301 tagttatttt ttcttctgaa ggcaaccaat attcgtttga tgatatttac aatcaggaac
    24361 aaagcaataa agactaatgt gattgttgct cctggaggtg tatctagata aaacgagcta
    24421 gttagtcctg acagcatccc tagaaatcct acacaaacac tgatagcaat cacgacattg
    24481 aagcttttgc ctaatcgcat accgattgct gcgggaagaa ccatgattgc ggatatcaaa
    24541 agtgcaccgg caatcgggat catcacagca atagccacac cagtaatcac attgaacatc
    24601 atcgacatca aatgaacggg tagcccatcc acgtgggcgg tatcttcatc aaaagtcaga
    24661 acatacatcg gccgtttgaa taaaaagaac aatataccga tggcaacgaa taagattcct
    24721 aaaaagatga cttgctccca tgtaatggtc acgatcgaac caaacagata ggattggata
    24781 cttgttgctg aattccctcc gctcaaattc atcaatacta acgctagcgc caaaccacca
    24841 gccattaaaa tggcaatgga gatttctgaa taggttcggt agatcgttcg cagatactcc
    24901 aatatcacag ctgctaatac aacgactagc atggtcgtaa gtgtaggatt aaggttcaaa
    24961 aagaatccta acgctacccc tgctaaagag acatgagaaa gcgtatcagc catcagcgat
    25021 tgtcttctga tcactaaaaa cacacctagc atcggggcga ttccggcaat gaagatagcg
    25081 gcaagaaacg ctcttctcat gaattcatat gaaagcaacg ccattgagaa tcctcctttc
    25141 tcaccagtcg gatctgtctg tccgcatact gtttgatatc ttcatgatca tgggtgatca
    25201 ttagaactga tttcccatgg acatgcgcac tatgtcggag aagacgataa aattcatttc
    25261 tggattcttc atccatacct gttgttggtt catcaagaac aaataagtca gggtcagtag
    25321 caaaaatacg cgctaaactg attcgctgct tttgtccgcc agacaattca cctattcgcc
    25381 gatttcgcat atcccacatc cctacagctt ctaaagcacg ctgtacatgt tgatgatctt
    25441 tttcagagag acgcttgaac cagcggcctc ttggatatct tcctgaacgg actaattcga
    25501 tcaccgtact aggaaaacct gcattgaaag atgcaacttg ttgaggaata taaccgatac
    25561 ttaatttttt tccttcttga tttttctcag caatctttat cattcctttt gaaggtttca
    25621 gtaatcctaa cgatgctttc accaaggttg acttggctgc tccattttct ccagttaaaa
    25681 tgacaaattc acccgcatct acatgataag agacatcttc tagtacaggt tcatcatcat
    25741 agtaaaaggt caaatcagat atttcgatat aacgcacctt acaacctcca ttctaaaact
    25801 taattgatac tttcttttaa agctttcaga tttttttcca tgacagaaat ataattttcg
    25861 cctgctttga tttgttcatt agtcaagctt tctaaaggat tcaacacttc tagcttcact
    25921 cctgtttcat tcgacaatgt ctcagctacc ttcgaagagg cattttcttc aaaataaatc
    25981 actttgatgt tgtttttctt cacaaattct tttagctcag ctaagcgact tggtgtgggt
    26041 tcctgatctg gtgaaacgcc cgaaatcgct acttgtttta agtcgtattg attcgctaaa
    26101 taagcaaaag cagcatgctg agtgacaaat gtgcggtttg ttgcatcttt tagctcatcg
    26161 gagtattttt gatccagtgc ttcaagcttt ttgatataag catcggcatt cttcgtaaaa
    26221 gtttcctttt tatctggata tttttcgcct aattcttcag caatcgttct gacttctttt
    26281 atagctaata ccggatcgag ccaaacatgt ggatcgtatt catgtgaatg accatgccct
    26341 tcttctgatt cttcatgttc gtctgcttct tgcgattcta aacggtcgat tcctttagct
    26401 gcttcgatca tcaaggtctg tttgctatcc actgaatcct ttaacgaatc cacaaaaaat
    26461 tccatgtctg aactattata cacgaaaaca tctgcatcgg aaatttctgc tctttctttt
    26521 gcacttggtt cgaaatcatg cggctccgtt ccagcaggga tcaaaagttt cacgtttcct
    26581 tcatccccta cgatctcttt tgtaaaatca tacatcggat aaaaagtcgt aacgatcgtc
    26641 aaatcctctt ttttgtctgc ttccttgttc gtatttccac atgctgcaaa cagtaaagca
    26701 cctatcatta ccgtagctgt caaaagatat tttttcattt atatgctcct ttcaatgaac
    26761 aaatcggaat tttacgattt attaacgtga actaatgtat caaaataaaa aaacacagtc
    26821 aatagaaatc catcaatttc tgatttaagc atgtatattc ttgattaaat cgtaaaatgg
    26881 atgagttgct gctcatatct agccatttca ctacaataaa aaactgaaga ataccatttt
    26941 aggattcctc agtttttcat cacctatttt acttcttata ttttattgca gggttcgtac
    27001 taaataaact tcctcacaaa aaccttttaa cccattatat actctctgcg ctcttgaata
    27061 atgttgacac aaggcaaaaa cggttggtcc gcttccactc atcaatgcag catctgctcc
    27121 gtacttgatc atacgctctt tgatttgatg gatgactgga tgccgctttc ccgttatatc
    27181 ttctaaactg tttcccattt ttttgatcat ctgctgataa tcttgctctc ggatggcttc
    27241 agcaagtccg tggatgtctt gatgttggat ggcttgcgta tctacttctc taaacactgt
    27301 acgtgtagag acactcattc ttggtttgac caacacaacc cagcactgtg gcatagaagg
    27361 taatacttgg atttcttccc ctttgccacc gacaaatgcc gtacttccgt agacacagta
    27421 aggaacatct gtaccgactt ccaaaccgat ttctgccagt tcttctaacg aacagcccag
    27481 attccataat tggttgatcc ctcttagagc agctgcacag tctgtacttc ctccgcctaa
    27541 tccagctgct actggaatat tcttcttaac aaagatcttg acaccggttt tgatattgta
    27601 tttatttttt agcaataaag cagcttgata aacattgttc cgttcatcta ccggtaaaaa
    27661 tgctttattt gtttctacaa tgattttgtc ttctgttatt tcttcaaaaa atagatgatc
    27721 tgccaagtct acgctcgaca tcaccatttc caactcatga tacccatctt gccgtctata
    27781 taatacatcc agtcctaaat ttatcttggc tggcgctttt tcaatcaatt ccatcctctc
    27841 acccattcga aaagtctaag tcgcaagtat tctatcatag ggaaaaataa aagtatagct
    27901 tatgtctgcc tagtggttga ttttgtcatc gtttcaacag ctttcacaga attttctctt
    27961 cataatccaa acaagttcta gtgattctta taattctgtg agcacttctt ctgccaaact
    28021 cggaacattt cctttttctt ttcctatcag actgagtagc tgcatggtag caaatccgaa
    28081 attacttcct ttcctataag caaaataacg tccttcccaa tgatcgacat attttaattt
    28141 cttttcataa gcagactgga aggaatagaa aaaattacca taattatata cgatatgcat
    28201 gactttttct tgaaagaaag aaaaatctgt ttctccaaca ttagctaatg gagctaagcc
    28261 tagattggct tccgagtagc ccattttctc gtatacaata aacagattgg ctaacagata
    28321 gtcagctaat tcctcagatt ctttaggtaa gacccgcaac aaatcatatc ccgcctgctt
    28381 cttcgtcatc ggctgagcgg tgatgaagcc aacgactttt tgatctttac ggacaatacc
    28441 gacaccgcta gataatacat atgatttatc aaatcgtccc acagagaagt atttttctcg
    28501 tgcaccttga agccattttt gtgaaacttc atttacagct tgatgtaatt cttccggcag
    28561 ttgatcgtac caagtaaaat ggtatccttc tttcatcaaa cgttgatatt caagttgctg
    28621 actcagccga gacaagtctt ctgttgctag atcaacaatc cctgcttcac ctactttcgt
    28681 gaagtgaaaa cccaattcat gaagcatcac tacgtagctt tctgatatct tataaaacgc
    28741 aagctgatag cctaaacaat ctgcttgttt cataaactga ttcgttgctg cccgcatcat
    28801 tttaggattg ccaactggat ctcctaaaac aaagcatttg tttcctttga tctgataacc
    28861 aaaaacgact tgatcttggt cgtcttcttg gtaataaaaa taactgtaac ctgacaagcg
    28921 aagctgatgg cttgtagctg tgcctccgta tgtttccaat aaacggtcaa aacggtcttt
    28981 ttcgtactca ctgccaagct tcgtagtatc ttcagctaaa tattgataaa gcgccactaa
    29041 agctagcaat gagatgccca aaccaataag ccctgagaac cacacatcat ctgaaggaaa
    29101 caaaataaaa tgatttcctg ttattcgacc gactaaaaag cgtccgctgt gatagcctgc
    29161 aattgcgtaa acgataaaca aaaagccgaa caagctagca tcaaagatta tagctcccca
    29221 agaataaacg aattttgttc gataaaattc ttttctggat aaccacacag ctaacagaat
    29281 caagacatat accaatatca actgccaaga taacgtacgt gtgattgtat ttaaaatacc
    29341 aaaagatagt aaagcaatcg taggcagaaa tgcctttttg acttttactg aaagtgctct
    29401 agcaaggccg agtaataaaa agccaaccaa tagattcact gtctgatcta aaaaattgaa
    29461 tgagaacggc aataatactt gaaatagccg actgattgca gacagattag tgattgttga
    29521 tagaagtacc atcatgatcc ccgcaaaata gacagcactt acgagcacga tatgcgcaac
    29581 cttttggaaa aacagtcgcg gaatgttatc taaaaatcga ttgattttga ctcctgtatg
    29641 tgtgatgaac aatagaagtc ccgtcataaa aggtagaaca taataaaaca accgataata
    29701 taatagccaa actactgcta catcttgccg aacagacaat tgactcattc ctaagatcat
    29761 caaaacgtca aaagtcccca ttccacctgg gaccatcgtc agcattccta tcaatgtagc
    29821 aatcatgaac ataggataga tcgaaagcat cgaaatatct attctcatca acttgccgat
    29881 gatcaaaaat accgcaaggg ctcccgtcca ttgtccaaag gatgccagta gcagaccaag
    29941 caagcctttt ggataaaact cgaagaacaa tgtctttctc tttagataag caaaaaagaa
    30001 aatgactggt gctaaaaaac taccgccgaa aagccagatc caatagcttc gaaaaatact
    30061 ttctgactga ataaaaaaga catcaataaa tgtaagaaac gaccatacag acaaaccagt
    30121 cagcataaat agtgcgactt ttgatacagt ggctaaaacc atttttctat ttgtctgctt
    30181 tccataaaaa ctagcccgca gacttgctcc taccacacca ccaaaaccgg cgagattgtt
    30241 gatcgtgttt gttacccacg cagcaagaag aaactctttt ctttccattt ttggttttcc
    30301 ttgtttttct aagactctga tcgtcaccca atcatacaac aacatcggag tgacacccag
    30361 cagtccagcc agaatcatga gcaggatcgt catgcggctt tgttgtccca tcctttgcca
    30421 aatatcttgc caactcatgc cattagcaat atttgcgact tgatttgcca caaagactaa
    30481 cacggagccg aaaaaaatca gttttaaaat cagactatgt tcctttatcc attgcagcat
    30541 caagtatcgt ttatttttca cattttccca ttcctaactt gtatactttt gtgtcatacc
    30601 ccaatgttat cttatttatt ttaatttttc cactttagac ctgttctttg cttgcgatga
    30661 tagaaaaaga aagatatcct aatgctaaag gagaggataa catgaaagta ggatttatcg
    30721 gcacagggaa tatggcacaa gctattattg atggtttatt aaaaaaagga acagtctcga
    30781 aagaagaggt gttcgtttcc agtggacatt ttgaaaatgc acaaaaattt gctgctgaaa
    30841 ctggcgtcca tgcatgcaaa agtaatcagg aagttgcatc acaatcagat atcgttcttt
    30901 tagccgtgaa accaaaaatc attgaaaaag tattggaaga actaagagaa tatagccaga
    30961 aagtcttatt catttctatt gcttcaggaa aatcattaat agatttagaa acagcgcttg
    31021 aagatcctca ggcctccatc gtacgtgtga tgccgaatgt caatgtcagc gtaggagcag
    31081 gcgtttctgc gatttgcaaa aatgaagctg ccacggagga acagcttcag caagctacga
    31141 tgatttttga agcaatcggc agcgtctatc ctttagcaga atcagatttc agtacattca
    31201 ttggccttgc tggcagctca cccgcattcg tttacatgct gatcgatgcg atgggacgga
    31261 ctggtgtact gaatggtttg tccaaacaga cagccactga gattgctgca aaagcaatta
    31321 tgggttcttg tcaaaaattc ctttcaagtg ataaaaatcc atgggaactt gtagaccaag
    31381 tttcttctcc tggcggtaca actgttgcag gtgtagttgc cttagaagaa gcaggattca
    31441 tcccagcaat catcaaagga atcaatacga cgatcgagaa agatcttgag atgttgaata
    31501 aaaaataatg atagcaatgt tttttcgtgc cttacaaaaa aagaagagct gtggcttttg
    31561 ccgcggctct tcttttgtat tttttattat ttagcataat cagttgcacg agtttcccga
    31621 ataacgatta ctttgatgtg tccaggataa tccagttctt cttcgattcg tttacgaata
    31681 tcacgtacta aacgaacagc gtctaaatcc gagatttctt ctggcttgac cattacccga
    31741 acttcgcgtc cagcttgaac tgcgtaactt gattctacac cggcgaagct gttcgaaata
    31801 ttttccagac ttcttaaacg acggatgtag ttttctaatg attcacttcg cgcaccaggt
    31861 cttgctgctg agagcgcatc tgctgcagct acaaggacag agataacaga agtagcttcc
    31921 acatctccat gatgagaagc gatcgcgttg attactactg ggttttcttt gtacttggca
    31981 gctaattccg caccgatctc aacgtgagat ccttcaatct catggtcaag tgctttccca
    32041 atatcatgga gcaacccggc acgttttgct aattggatat cttcgccaag ctctgctgct
    32101 aagataccag ctaattttgc aacctcgacc gaatgcttca agacgttttg tccataacta
    32161 gttctgaatc gcagacgtcc gatgatcttg attagatctg gatgaagtgt atgagcaccg
    32221 acttcaaacg ctgcctcttc cccgtattcg cgaatacgtt catccatttc tttacgagat
    32281 ttctcgacca tttcttcgat acgcgctgga tggattcgtc catcttgtat cagtttttcc
    32341 aaggtcatcc gtgcgatttc tcttcggatt ggatcgaatc cggaaagaac aactgcttcc
    32401 ggtgtatcat cgatgattaa atcgatacca gtcagcgtct caagcgttcg aatattacga
    32461 ccttctcgtc caatgatacg acctttcatt tcatcattcg gaagggtaac gactgaaaca
    32521 gtcgtttctg aaacttgatc tgctgcgcag cgttgaatcg ctaatgataa taagtttttc
    32581 gctttgcgat ctgcttcttc tttggcacgc tgttcagatt cttttaccat tagagttaac
    32641 tcatgattca gctcttcttc agtcgatttc atgatgacat ctcgtgcgtc ctcttttgat
    32701 aaaccagcaa ttttttctag ttctttttgt tgatcttcaa tcattttttc aacgtctttt
    32761 tctcgctctt caattaattg ctgttttgaa ctaagtgctt cttctttact ttcaagtgag
    32821 ttctcgcgtt tttctaacga gtcatcttta cgattcagcg tttgttcgcg ttgaatcaaa
    32881 cgattctctt gagattttaa ttctaactta ctttctctca gctcactttc aacttcagaa
    32941 cggtatttct gattttcttc cttagcttct aacaatgctt ctttttttag agtttctgct
    33001 tctttttttg cactatcgat gattccagca gctgatgatt gtgcaccagc tatttctttc
    33061 tcgtgacgtg actttgcgac cataaaccct aaaccaagac cgacaattaa accgatgata
    33121 gcgaggagaa tgttgaatac cataaaatcc acctccatac tatctttttc atttttatca
    33181 tctatacagc ttctatgata aattattcta aactcgtcaa tatgcatctt cgcatatatg
    33241 tgtacaaaaa acatgcacaa ctttattcta atgtttgtac cccgtagtgt caactttaaa
    33301 taaacaaaga aacggctttc tacttattca ttaaacgatg gtttttaaaa taaatgacac
    33361 tagtttcata taggtaaacc tttaaattga gaaacttttc tattaaatta ttctttgtag
    33421 atgaacagat atttttattt tatgtaccca ctcgtataat taaataactc acgatttctt
    33481 tattcaataa aaaaacggca ggtcaaggag agtacctact cttcagacca gccgtttttg
    33541 tttatcataa tttttattct tctactaaag gcaattcttc ttgtcctttt tcatcttctg
    33601 ggacagcgac ttcttcacca ataccataag ctgctctaac tagagcagaa acttctgcca
    33661 tcatttcagg atgattagcc atatagattt tagcgttttc ccgtccttga ccaatccgat
    33721 cttctttata agaataccaa gcaccgcttt tatcaacaat gtctttttct actgccatgt
    33781 ctagaagttc tccttcttgt gagatcccta aaccatacat gacatctact tcagcgattt
    33841 tgaaaggagg tgctactttg ttttttacga ctttgatctt tgtacggtta ccaacaatat
    33901 ctgtaccttg tttcaattgt tctgcacgac gtacttccaa acggatcgtt gcgtagaatt
    33961 tcaatgcgcg tcctccagga gtgatttctg gattcccaaa catcacgcct actttttcac
    34021 ggatttggtt gatgaaaata gcgattgttt ttgttttgtt gatcgaacca gagagtttac
    34081 gcaatgcttg agacatcaaa cgtgcttgta acccgacatg tgagtcaccc atttcgccgt
    34141 cgatttctgc tcgtggaact aaagcagcaa ctgaatcgac tactacgata tctacagccc
    34201 cacttgatac taaagcatca gcgatctcta gaccttgttc tcctgtgtca ggctgtgaaa
    34261 gaagtagttc atcgatattc acacctaatt tttgtgcata ttgcggatct aacgcatgct
    34321 cagcatcaat gaaagcggcc gttccgccat ttttttgtac ttctgcaata gcgtgtagtg
    34381 caactgttgt tttacctgaa ctttcaggtc catatacttc gatgatacgt ccacgggggt
    34441 aaccgccgac acctaaagcg acatctaacg caagagagcc acttggaatt gtagagattt
    34501 gttggtcgat tttttcgccc aatttcataa tagagccttt accatagctc ttttcaattt
    34561 ttttcagtgc agcatctaag gctgctttac gatcatctgc caatacgata atcctcctta
    34621 tatttacaaa tcagagcaac atttcattat ccttatcata tcttttttag tgaaaaaaag
    34681 caagaaaaaa ccgaacaaat attcgcattt atcattttct taaaagctgt tttctcaaaa
    34741 gatcaaatcc ttgcataacc gcattatatc tgatagcagc acgatctctg gcaaagtgat
    34801 atttttccga aaccacgccg tctttagatg aaatagcgat ccatactgtt cctgcagatt
    34861 gaccttctaa cgtgtccggt ccagccactc cggtgaaagc tacactgtaa tctgttcttg
    34921 ctatctcacg tgcttgaatg gccatctgct ccacacattc tttgctgact gttccatatt
    34981 ctgctaatag ctccggatca atctccagaa aaccagcttt tgtttggagc gagtaggtaa
    35041 cgaatccgcc tggaaatact tcagatacac cagcaatgtc gcctaatgcg gcttggaagg
    35101 cgccggctgt caaactttcc gctgctgtta cagtctgctt gttttctttc agtagttcca
    35161 ctacgacttt tgctagcgaa ttatcatcgc cgtatccata aaaatattcc cctactcgtt
    35221 cttggatttt ttcttctaat gctaaaagag cttgattccc tgcctgaaca tcatttgttt
    35281 tcactgtcag tcgtaatgtc acttcatttg gtttggcata tggtgcgatc gttggattga
    35341 tctgtgtctc aatcagatct tttagctcag tgaccagtcg cgattcacca atcccataaa
    35401 agcgcaaaac tttagaaatt agtttttctt cagaaggaaa acgttcctct agtaaaggac
    35461 gtacttgttc cacaaacatt ggtttcaact cattaggcgg accgggaaga aggatatacg
    35521 catgtgtatc tgtttgataa aaagtcccta aagcaagccc tgtacgattt ggtagaggaa
    35581 ccccgccttc gataatctgg gactgttgca gattgttttt ggtcattttt cgatgggttg
    35641 tttcaaaata tgccaataat tttttgtatc cttccgtatt ttgtatgaga gacttaccga
    35701 ggtgagccgc agttgcttct tttgtcaggt catcttctgt cggtcctaat ccgccacata
    35761 agagtatgag ttcacttctt gtttcagcta gagcaatcaa ctcttctaaa cgctgctgat
    35821 tatctcctac aactgtttga taataaactt cgatacctag atcagctagc tgttctgaca
    35881 agaaagtggc attcgtattc acgacttgtc ctagtaaaag ttctgttccg acagctatta
    35941 tttctgcttt cattacttcc cgctccctta tatagtatac gctgtatttt tatatttttt
    36001 tatttaaaaa gagggcaagg agctgtgaca aaaatcttgt cacagctcct tgttccaaat
    36061 aaacagtgtt ctcctgccaa aacctcggtc ataagtcaca atatacataa aacatgaaaa
    36121 gctgtttttt gaaattatcc cttgtgactc agagttagac ggcaggctca caacctctcc
    36181 actaaacgat acttacattg atcctttgaa cacaccgctg tttttgatga agtaatccac
    36241 acctgaatag atagtaaaga tcagacaagc ataaagcatg atttgatcta ctggaatacc
    36301 gatcaggctg aatgggatat tattgataaa cagcaagata atagcaacca tttgtgtagc
    36361 cgtcttgact tttcccggcc aagctgcagc catgacttct ccatgttcga caagtagtaa
    36421 acgcaagcct gtgacggcta attcacgaca gacaatgatc gctactaccc aaccaggggc
    36481 ctttccttgg tcaaccaaca tgataaaagc agtcataact agcattttat ctgccaacgg
    36541 gtccgcaaac ttgccaaaat tagtgacaag gcctcgcgca cgggcaattt ttccatctaa
    36601 ccagtctgtg atactagcta aagcaaaaat aactgcacct actagctgtg tgacagccag
    36661 tgtggtgtct cctacgttaa attgtcccca atctaaaggt aaacctacaa ccaaaatgaa
    36721 aatcgggatc atacaaattc taagtacagt taatttattt ggtaaattca cactatcgac
    36781 tcctttcttc cctattctac gtgactatca gcgaagtttc caccgatatt atttactttt
    36841 ccaaatgaat ttattcaaag gagtattttt attgaaattg atctttttga attaacgaag
    36901 aaggaccgcg acacagattt gtcacgatcc ttctttttta tacctacaag taaacagatg
    36961 cgtaaactaa tttatacgat cattctgcgt attgaagagt aaggttcaca ttttttggac
    37021 tctgattgtt ttcccctgga ttaactggta cggattctcc attcgctttg atcgttgcat
    37081 tgcttgctgc accaatcgtg atggtcgcat ttgttgctgt ttccggtaac acggtactct
    37141 gtgtttcatt tgctgccagt gtcccttgat aaacataggc attgtctact agcacaccta
    37201 accatacacg attgacagca gtaaattcaa gggttacagg cttggtagcg tctgtgatat
    37261 ttactgcgat ggcactgcca gaatcttctc ctgtagctat tgccattttc ttttcttcac
    37321 ttgattttgt tgttgattct actgtagaag actctttggt ctgcgtgctt tgctctgagg
    37381 aagaggactc ctcgactgat ccttctactt taagcgaaga agctgtgtct ccgattattg
    37441 gatcagcttg acgatcttgc caagtcatat agcccacgac aacgacaatc gccaaagcaa
    37501 ccaatcctaa taaaatgaca ggaagacttg tccaaaagcg acttggatgc gattcttcct
    37561 gatgcattgc ttttctagaa gtacttactg tttcaggctg cggacgttca gggaccgatc
    37621 ctgtcaattt gcttttccca tcaaaaacat cgactaaatg gtctccatct tctcctacag
    37681 cttcagcgta ttgccgaata aatgcccgca cgtaaaattt accaggcaat tggtcaaaat
    37741 catcattgtc gattgcttcc aaataacgtt tttgaatttt tgtaatctgc tgtaattcat
    37801 ctaaagatat ttttttattc aggcgtgctt gccgtaattt ttctccgatg gtttcaaaag
    37861 ccactcgttc atcttctcca gtctgtttga ttctccgaag catctgctgt tgcaacgaaa
    37921 gacgttatgt ttgggtgctg tgacaaaagt catgtcacag ctcctttttt ccgaataaac
    37981 attgttctcc tgccaactcc tcggtcacaa gtcacaatat ccaataaata taagaagctg
    38041 ttttttgaac ttgttccttg tgactcggag ttaaacggca ggctcacgac ctctttctta
    38101 aacggtgttc aatcagctgt tcctcggtat tagctcaaaa accggcaaaa tataaggaga
    38161 tatttttccg tatgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttcct
    38221 taaacggtgt tcaaaagctt gcatctgcgg taataagtcc aaccaagtta aaaacattaa
    38281 gaagctgttt ttacttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc
    38341 ttggtacacg gtgttccaga agtagcttct tcggcaataa gccgaaatat cacaaaaatt
    38401 tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctgaccactt ctgtcacaac
    38461 ctctttgatt acttcgtttg attttatttt aatataagtt gattaaaaga gagcatgatt
    38521 tgttttattt tctcactaat ttttccaaca caactaagaa taccataaaa gctgattttg
    38581 gaggaggttc ctactacaag tctaaaacga aatttaagac ttttcctcat aaaatactgg
    38641 tttattttgg tctcatgtaa aactcgctga aggcctcttc acttataaat gcttccccag
    38701 ctgccagtac gtctttcatt tggatcgaat cgatgatttc aggaagatca aataaagttc
    38761 gatcgccaaa taaactttgc gtaaattgat tggcaatata ttcgatcgaa tttaatgatt
    38821 ggaaatattg tccaagcatt ttcttcttca gcaaatcgag atttgtttct gacacttccg
    38881 gatcatcagc gaatccaaga atgatttctt tgactttttc tgctgctttc tctggttcgt
    38941 ccgtatctcc gctgaagtcc gcaaagtgaa attcacgatc caagctgaat tcaaaaccaa
    39001 agctgtcatc gataattcct tgattgtaca tcgctagata gtttcgagaa gtattgccta
    39061 aaatcatttg gaacaacaga ttgattgctg ttttatagcg taacagttct gttccttctt
    39121 gcggcaatgt gtctaatcct ttaataccaa gtacaaattt atctcgtgta atggctgctt
    39181 ccaatgcact ttgtttgatg atttcttttg tgttttcagg gaaataacgt acaatttctt
    39241 gctttggagg gaaatttttt gcttcttggt tttcccgaat aagtttcatc aatttctcag
    39301 gctccatctt accaactaca aataaaacca tattgcttgg ctgataaaac gtccgatagc
    39361 acgtatacaa gtcttgagct gtgattttgt cgatactttc aaccgtgccc gcaatatcga
    39421 tatgcaatgg gtgtgtagga tacaagttat ttagtatgcc aaaaaacatc cgccagttag
    39481 ggtcgtcttc atacatttgg atttcctgac cgatgattcc tttttccttg tttacagttt
    39541 cttctgtgaa gtaaggtgct tgtacaaaat cgatcagagt cgtcagattc ttttctacct
    39601 gatccgtcgt agaaaacaga tagctggttt tcgtaaaact tgtgaaagca ttggcggaag
    39661 ctccttgttt cccaaataat tgaaagacat caccatcttc tttttcaaac aacttatgtt
    39721 ctaaaaaatg ggcaattcca tctggaactt tcaccttttc tttttcacca tagggaataa
    39781 attcgttatc gatcgaacca taattcgtac tgaacaaacc atatgtcttg tgatagtcat
    39841 ttttaggcaa caaatacacg gtcaaaccgt ttggcagtac ttcatgataa agtgtttcat
    39901 tgatttgctc atattctgtt ttattcattt gcatttcctc ctgctaaaaa gaagattgcc
    39961 tgcaattcga tttgctcagc tacttgttgt atctctttga tcgttacgct ctccatacgt
    40021 ttcaaccatt cttcatcaga taattttgtt tccggcagcc agctgtccaa aaaagaagct
    40081 tcgattgccg cttgcggaga gtctagagaa agcagatatt ggtttctcag cattgctttt
    40141 gtctgagaca gttccaactc tgttatttca ccatttcgca aactttctaa ttgctcgtga
    40201 atcagatgaa gtacttgatt tcggttcttt tcatcgatac cggtttggac actcatgaat
    40261 cctcggaacg tatccacgct actagaggca taataagcta gactttcttt ctctctgaca
    40321 ttcatgaaaa gtttagagtg aggaaaaccg ccaaataaac cgttaaagac cattagcgca
    40381 aaacgttctg gttcatcgta atacacattt gtctgataag ctaggttcag ctttgcttga
    40441 acgattggct cacgtacttg tcgttccttc acgatattca cttgaggttg ggtataaaac
    40501 agatctggat aaactgtttc ccgcgactca aatggtaatt gcccaactgc ttcagctgct
    40561 ttgtccggat caacatcgcc gacaacaaaa atgtcgattt gatcatttgc catcatttct
    40621 tgatagtagg acgctagcga actagcagtg atcttgtcca aatcttcgac tacgcccaac
    40681 cctgggatct tttgttccgg gctgttttca aaataaagtt cttgcaaggc ataggaagca
    40741 aaagtttgtt tatcttcctt caaactttcc aaatatagac gcagattgtt cttttccaag
    40801 tcaaacgtca actgatcaaa ctgatgattt ttaatatttg gataaaataa aacctctttt
    40861 aaaaaatcta ccgcttgaga aaaaaggttt ggatcattga catattcacc attcacaaaa
    40921 ctgatccctg cgtttagcca atgtaaattt cctttttttc taactgataa tccaaagctt
    40981 gcgccataaa gctctgcaag ttgcgcactt aactttgtct gatccgaata attcaaacta
    41041 tttgtttcca acatgctgct gagaagtgaa cgtttcgtga tgacttcttg ttgcagacgc
    41101 gcagtaaaac ggataaaaat ccggatcgtt ttgtattgtt ttgttggtaa gacatgaaga
    41161 ttcacgcctt ctgccaattg atacaccata tttatatgct ccttttcaca gttgattgcc
    41221 cgcttactct tttaatgggt caacctgcct tttttactta ttcctctgct tgaaatttat
    41281 aagttcaggc aattcgccgt tttttctaaa tgatgttaca ctttatagta tagcatagat
    41341 gttttttatc aaaagaaaca gacggctaaa agcgtatatt gtttttttat tttttatttt
    41401 tcgatatact aaagacaaat aaaagaaggg agggtcattc atgatcaaag aattcaaaga
    41461 gttcatcatg cgtggagatg tcttggatct tgctgtcggc gttgttattg gtagtgcgtt
    41521 tacaagcatc gtaaaccaag tggtgcaagg cttgatcaca ccactaatag gttggtttgt
    41581 cgcaatgatc acaggtactt ctgatttaga aggagcactt tcaattcttg actggtcgcc
    41641 gacaaaaggc gtcacatttg cgtttggtaa cgttattagt gctatcatta catttctgat
    41701 cactggtttt gtcttattct tagttgtcaa agcggcaaac cgtgcgaaga atttacgctc
    41761 caaagaagag caagtggaag tggaagaaac tcctactgca gaagattatc ttagtgacat
    41821 acgcgatctt cttgccaaac aagtggcaga agacaataca catccagtag agcaaacaaa
    41881 tctttccgat acttctaaat aataaagaat ctaaaaaaaa gaaagccgat tttcagtgtc
    41941 ggctttcttt ttttagattc ttaacttgct acttgttcct ttttcatgtc gatatgtgga
    42001 atatcatctt ccaaatacac atctgagatt gccttgaatc caaacgactc ataaaaagct
    42061 tgtaggtatt cttgtgcgcc gatcacgatt ggtttttctg gaaaattttt ctggatcatg
    42121 ttaatcgttt cttgaacaat ctttcttcct aaaccatctt tacggttgtc ctgatgaaca
    42181 aggacacgtc caaaatggat actctccgct tcttcatata ctcgcgtgta ggcaaggatc
    42241 ttcccatcag tatcttgaaa aaacgtatgc caagcttctc catcaatgtc atcaacttct
    42301 tgataaggac actgttgttc cacaacaaaa actgcgattc gttctttgac gatcgcgtaa
    42361 aactctgctg ttgacaattc ttcaaatttc tttacctgat attccactaa gcaaacgccc
    42421 cctgcttttt tattcttagc ataccgattc gcacacaaaa aagcaaacga accttacgaa
    42481 tctcaggctc gtttgctttt taaactgctt cagttaaaaa ttcgatctca actgtccgag
    42541 taagtacatc tgaatagctg taagatactc gttcaaaaga attttcttca ggatccaaat
    42601 caacaacgaa tactgaagga taggtttctg ttaaaacgcc gcggcgttct gtttgacgct
    42661 ttcttcctgt ctgagcaacc aacatgattg ggctgccgat acgaccttct aaatctttct
    42721 tgattgaagc taaagttgtt ggcatacagt tcacctctac tatcaactat accacatatt
    42781 tttaaaattt tcaagtttac cataaaaaaa aaagaaatgc aataaaaata aataagaagc
    42841 tcattaagat ttttctaaat tattcctcat tataaaattt caagtgtttt tttattttga
    42901 gttttactct cccgtaagcg ctcattactt gcttgtgatc cattgctaaa cattcagcca
    42961 tgtctacaaa atcaacgcct tgcatataat aatgaaaaat tttagcttct atttttgaaa
    43021 actggatttc gcaattttcg attgcttctt ttaataaaag atgctgaatt gctaaaggtt
    43081 cttgcaatgt gatctctgct aaaaagtctg gtccttctgt ctctattttt tggtcgattg
    43141 agacttcatc tttttgatca cgacgcttca gcgcgttctg cttcctcaac agagaataga
    43201 tttgattgct tataacgctt ttataataac ttccaaagct aacacctttg cttttttcgt
    43261 aagttctcaa tgcctgatat aaagcgatcc ttgcttcttg ttcccaatcc tcagaaacat
    43321 aatttcttaa ataataggtg tttttcaaac gtagtaaaag tggaaaatat ttttgataca
    43381 gggcagcaaa tgcttcttcg tcaccattac gtgcagcgcg caataactcc tcagacataa
    43441 aataattcct ccataaattc gtttatggag gaatcttatc atcaatgatt catcgaactg
    43501 attagaacga tatgttattt attttttctc attaaatcgt ccaatttttg ggacaatttt
    43561 tttaactgct cttcattcca tggagaatta cgtcggaaat caataaaatg catatcttta
    43621 ttttcttggg ctattgtttt ttccgttttt tttatcgtct tatataattc ataagcagaa
    43681 gttcgtaatg ctccttggga aaagatcatc cactgttctg ctaaatcgct tgtcgccact
    43741 gtcacttgtg tcaaacggtc attcagctga ccagcgattc tctcgatata actgtcagcc
    43801 gtttcgtctt ctttcgtaaa aacaacatcc aactggtatt tcttataatt ttgttggatg
    43861 cccggaacta gttgggcatc gaagacaacg atgacttcca ttccttcata tttcgcataa
    43921 tttgataaac gatgtaaaag agcttctctt gcatccgcca ttttgtcctg ctttttaagc
    43981 tggacaagtt ccggccacga accaatcatg ttgtagccgt ctacaatcaa cagctgtttt
    44041 ttcatggtct actccccctg acgttgggaa aaagcctgat acataagcaa accagcagca
    44101 acactggcat ttaagctctg gacgtgcccg gtcatcggga tcgtcagcaa ttcatccatt
    44161 tcttttttca atcctggact cattcctttg ccttcattac caatgactaa agcaattgat
    44221 cctttggcat tccatttttg gaagtttgtg ccggtcatat ctgtgccaaa tacccaaaat
    44281 cctgtttctt tgagctgttg cacagcttgt accaaattcg tcacgcgtgc aacagggaca
    44341 tgttcgactg ccccagtgga agtctttgtt acgataggtg tgattccaac tgctcggtgt
    44401 tttggtatga tcacaccatc gacgccactt gcgtctgctg tccgtaaaat cgacccaaaa
    44461 ttgtgtggat cttcgatgct atccaaaatc aaaaagaagg ggtcttcttt tttctctttt
    44521 gttcgttcaa tcagttggtc aagggataaa tattcataag gtgtaatcgc aagaacgact
    44581 ccttgatgca cgccgtgatc gctcaaagtt tctaattttt gtttaggaac ccatttgact
    44641 ggcacagctt gttcacgtgc gatttctttc agttcttcta ctttttctcc tcgtgaatct
    44701 tcttgaagaa agagtttatt ccctcgccct tgttgtagcg cttctactgc ggcatggtgc
    44761 ccaaagacga aattatcttc taatgcttct tcattttgat cagaaactga ctgatttcgt
    44821 ccagtttgct ttttatttga atatctattt tgttttttgt cttcaaatcc acgtttcgat
    44881 tgatgtttgt ttgttctttc tttacccatt tttttcacca actttctgaa tacaccagcg
    44941 gatcaattct tccatccgct cggtttgttt tgtcaaatgc agatagccca tgagcgcttc
    45001 gaaccctgtt gcgacccgat acgtcgtaac atcagcattt tttgcgctcg tatggctttt
    45061 agcatttctt cctctgcgat aataaagttc ttcttcttct gtcaaaagat gttcttccag
    45121 catttgctga atcaaaaagg cttgtgcatt cgcagaaaca taattcgttg ccgcacgatg
    45181 cagcttattg ggttttgttt ctccttgatc aatcaggtgg tcacgaacat agatttcgta
    45241 aatcgcatct ccaacataag ccaaggctaa accgttcaat tgtgtgtaat ctctcatgct
    45301 tctcttctcc atcgggttcc ttgcggtgta tcttctaata agatcccttt ttctttcaac
    45361 aaatcacgaa tttcgtcgct tcggacaaaa tcacgattgc ttcttgcttg atttcgttct
    45421 tcgatcaatt gttcaatctc ttcatctaat aactcttctg ctgtaaataa aataccgaag
    45481 atcgaaagcc attgcgagaa taaagcttct ccttgtgcca agacagcggc agaaactttc
    45541 ggctggtcta gataagtgtt cagccactta gcaagctcat agaccactgt gatcccattt
    45601 gctgcattaa aatcatcgtc catttcttcg atgaatcgct gttctaaatt ttctaacaaa
    45661 gcgattttat ccgcatcatc tgccaaattc tctgaggcag tttcttggcg gaatttcaaa
    45721 ttgtcaaacg tattcttcag tcgttgtaaa ttggtggctg cttctttcat cgtcgtttca
    45781 ctgtagcgga tcggacgacg gtattgtgtg gtcgccatga agaaacgcaa gacttgtgga
    45841 tcaacgtttt tgatcatttc atgtacagtg atgaaattcc ctagagattt actcattttt
    45901 tcatcgtctt cgccaatcgt tacatagcca ttgtgcatcc agtaattagc gaattttttc
    45961 cctgttttcg cttcactttg tgcgatttca ttttcatgat gaggaaattc taaatcttgc
    46021 ccgccaccat ggatatcgat cgtttctcct aaatgttttg ttgccataac ggaacattca
    46081 atatgccaac cgggacgtcc tttgccccat ggtgaatccc aagaaatctc gccaggtttt
    46141 gcttgtttcc ataaagcgaa atctaatggg tcttcttttt gctgctgttc ttcccctgta
    46201 cgctgacttg ctccgacttc cagttcatcg atggattggt cacttaattt cccataattt
    46261 tcaaatttac gggtacggta atacacatca cctgaagatt cataagcata gcctttttca
    46321 accaacactt gaataaatgc taaaatatct ggcatatgat ccatgactct tggatgcagt
    46381 gtagcaggtt cgacattcaa cgctttcgta tcttcttcaa atgctcggat gaaacgatca
    46441 gcaacttctg gtgctgtaat acctaattcg tttgctgtac ggatgatttt atcgtctaca
    46501 tccgtgaaat tcgatacgaa atcgacttta tagcctcgat attcaaaata gcgtcgaatt
    46561 gtatcgaaag caatggtgct acgagcattt ccgatatgga tataattata cacagtcggt
    46621 ccgcagacat acataccgac atgtcccttt tgtataggga tgaattcttc tttttttctg
    46681 gtcaatgtat tgtagatttt tatcattctg atctcctcac tttttctcct ttgattcgaa
    46741 cgacttttgc tggtactcct accgctgtag cgtcgtctgg aacatctttc aacacaacgg
    46801 cacctgcacc gattttggcg ttttttccga tcgttaccgg tcctaatatc tgcgcattcg
    46861 cagagagcat ggctccttgt ttaacagttg ggtgtctttt acccgtttct tttcctgtgc
    46921 cgcctaatgt tacgccatgg aataaaatca catcgtcctc gatttctgcg gtttcgccaa
    46981 tgacgattcc cattccatgg tcgatgaaca cgccagttcc aatcgttgct cctggatgga
    47041 tctcaacacc agttaggaaa cgccagaatt gagcattgat cttcgccaat aaaaagagcc
    47101 ggtgctgata taaaaaatga gagaaacgat gccaaaacaa ggcatgaaaa ccagggtatg
    47161 tcaaaacgat ctcagctgtc gaacgtgcag ccggatcgtt tctctttgct gcatcaatcg
    47221 ctcgggtaaa ccaactcatg actttccact cctttcgtaa gaattttatg taggaaatca
    47281 tcttcttata aagaaaagaa gcgcctttta aataagtttc cttatcaaaa gacgctttcc
    47341 gcgtggttcc acttttcttc ataatcaatg attatctctg acagctaacg cctgttatac
    47401 gttcttggct actttgtttc ctataaaaca gtttttcctg ttttctgtgt ttcgccaaga
    47461 ccactcccag aggcatttcg gcaaccattc attgatacct tgcaccaccc ggtatctctc
    47521 ttgtaatgat cagctgctta cttttttctg ttcatcgtgt ttagttcagt acttgattta
    47581 aatgtgctaa tgatttttca cgaccaagca attcgatcgt ttcaggcaat tctggaccat
    47641 gcatttgtcc tgatacagct acacggattg gcatgaaaag attttttcct tttacgccag
    47701 tttctttttg aacagctttg atggcagctt tgacagttgg agcatctact acttccattt
    47761 gttctagctg tgctttgaat gcgtggagaa cagtaggaac tgtttcacca gcaagtactt
    47821 cttttgctgc ttcattcaat acaggatgtt cattgaaaaa tagcgtagac agatcaacga
    47881 tttctgcagc atagctcatt tgaggttgat acaggctaac gatcttcttc acccattcga
    47941 ttgtcttttc atctgggttt tctgctacac gtccatcagc gattagataa ggcagacaca
    48001 tgtcagtaaa tgcatctaga tccattgctt tgatgtaatg gttgtttacc cattgcagtt
    48061 ttttcgcatc gaaagctgcg ggtgatttac ttaggcgttt tggatcgaac attttgatca
    48121 attcttggtg ttcgaagatt tcgtcttcgc ccacaggtga ccagcccaat aatgcaataa
    48181 agttgaacat tgcatctggt agatagccta attcgcgata ttgttcgata aattgcaaga
    48241 ttgattcgtc acgtttgctt agttttttac ctgtttcact gttgatgatc aatgtcatat
    48301 gtccgaaggt tggtggtgtc cagccaaatg cttcatagat catcagttgt tttggtgtat
    48361 tggcaatatg gtcatctcca cgtaaaacgt gagtgatttt catcaaatga tcatcgaccg
    48421 caacagcaaa attataagtt ggcataccat cgcgtttttg gatgacaaag tcgccaccga
    48481 tattatcgga ttcgaacgaa atagcgcctt tcaccatatc tgtaaatgcg tattctgtat
    48541 tgcgaggcac acggaaacgt acaacagatt ctagaccttg tgcttctttt tctgcttgtt
    48601 cttcaggtgt caagttcgca catgttcctg cgtaatgagg catttctcct cttgcgcgtt
    48661 gtgcttcccg ttctgcttct aattcttctt ctgtgcaata gcatttgtat gctcgattgc
    48721 tagcaagcag ctgatcaatc agcggttgat agatttcttt acgttcagat tgacggtaag
    48781 ggccgtattc tccaggattt tcaggagatt catcccaatt cattcccaac caagcaaggt
    48841 tttccaactg gcttttttcg ccatcttcga tattacgttt ttggtcagta tcctcaatac
    48901 gaataataaa gtctccatca ttgtggcggg caaacaaata attgaataat gcagttcttg
    48961 catttccaat atgcaggtgc ccagttggac ttggtgcata gcgtacgcgt actttcgtca
    49021 ttttcttcct cttctttcaa actagacttt gactaacagc aaaaattccg tcagttacgg
    49081 cttctcaaat atcatttatt taaagccact cagcacaaat tttacctttt ctaaggtaaa
    49141 tagtaaagcc aactggttga atttccttac cagttggctg aatttctttt ttattttgat
    49201 tgtttagtct ttttctctgt ctctttttta ttgtcgattc ctcgtcctgc atgtgcaggt
    49261 ttagcaaaga tcatgcgtcc agcagctgtt tgaagggcac ttgttacaac gacttcgata
    49321 cgttcattca tgtaatgctg tccatcttct acgacaacca tcgtgccgtc atcaaggtag
    49381 gctactcctt gttggcgttc tgtcccggct tttactacta gaacattcat cgtttcacca
    49441 gggatgacga ctggttttac ggcatttgcc aacgcattga tattaagaac aggtacattt
    49501 tggaattcag agactttatt caagttatag tcattggtta caatgacacc atctaaaagc
    49561 ttagccaatt tgatcaattt gctgtctact tcactgatat cttcaaagtc tccatcgtac
    49621 atttcgacag atataccctc ttctttttgc aaggcattta ggatatctaa tccgcgacga
    49681 ccacgcacac gtttcaaact atcccctgag tccgcgatgt attgtagttc gtaaagaaca
    49741 aaattaggga tcatcaaggt tccttctaag aatccagtct ttgtaatatc ataaatccga
    49801 ccgtcaatga tcacgcttgt atccaagatt ttatatttat ggaaattttc tcctgatttt
    49861 cgttctaaca gttgactctc aacttgacta gctgtttctt gctcgatttt tttgcttcgt
    49921 gaaccaaaaa ctttcttcca ttcttcgatt cgtgtcgttc ccattctcaa tcccagatag
    49981 cctaagatga tcatcagtaa aatcggcaat acactattga cgaatggaat ttccatattg
    50041 taaagagggg tcgagatcac aacacctaaa gtcaatccga tgatcgcacc gatcgcaccg
    50101 aagagaagat aagtcaagct gacctcactt agtttttgtt ctacttgttt gataatagct
    50161 gagatatgtt tggccaacag caaagataat aaaaagaaaa taagtgcgcc taacaggctg
    50221 ttggtaaatg tattattcag ccatccgttt gactgttgac cgattgcctg ccaagctgag
    50281 ggtaaaaatg aaatacccaa gcttgcgccg acaatgatca tcagcaaagt aatgacacgt
    50341 ttttgcatcg tttttcctcc gtttcgacaa tcatttatta gttagcggaa cacacgcttc
    50401 aacgtttcag ccaaagttgc tactccaact atctcgattc cttttggcgc ttcccagtta
    50461 cctaagttgt ttttaggtag gtatactttt gtgaagccga gtttttggac ttctttgact
    50521 cgttgttcaa tatgactgac acgtctgatt tctccagtca gtccaatttc accgatgaaa
    50581 cattccgttg gctgtgttcc tttttcttta tagcttgaag caatactgac agcgatagct
    50641 aaatcaatcg ctggttcatt taattttacc ccacctgcag cttttaagta agcatcttga
    50701 ttctgaagaa gcaacccagc tcttttttcc agcactgcca tgatcagaga tacccgattg
    50761 aaatcaagac ctgttgttgt tcgtttggca tttccgaaca tagtaggtgt gactaatgct
    50821 tggatctcta ccaaaattgg acgtgtccct tccattgcca caacgatagc agagccagtt
    50881 gcaccgtcta ggcgttcttc taagaaaatc tgtgaaggat tagcgacttc ttccaatcca
    50941 tgctcatgca tttcaaaaat cccaatctca ttcgttgagc caaatcggtt ttttactgct
    51001 cgcaaaatcc gaaaactatg atgttgttca ccttcaaaat ataacaccgt atccaccata
    51061 tgttctaaca ttcttgggcc ggcgatcgag ccttctttgg taacatgacc gacgataaaa
    51121 atggctatcc catttgtttt agcggttttg agtagttctg cagtggtttc tcttacttgg
    51181 ctgacacttc ctgccacact tgtgatgtct ggctgcgtca tcgtttggat ggaatcaatg
    51241 ataacataat caggggagat atgttcgatg gcacgactga tttcgttcat atctgtttca
    51301 gcgtatagat aaaattctgt gttgatactt ccgaggcgtt ccgcgcgtaa ttttatctgc
    51361 tctgcgcttt cttcgccgga tacatataag acttttccgc ctatggctgc taattgctga
    51421 gaaacttgta acagcaaagt ggatttcccg atacctggat cgccaccaat caagaccata
    51481 gaccctggca ccacacctcc gcctaacaca cggttcagtt cttctaattt tgttttgatc
    51541 cgaggttctt ttttagggac gacgtctgcg atttttgttg gttttgcttt ttctcctgtc
    51601 aaacttgtcc gagttctgcg gtccgttgta tcttgttcga tttcttcgac catcgtattc
    51661 cattttccgc aatttgggca gcgtcccaag aacttaggcg acacataccc gcaattttgg
    51721 caaacaaatt gtacttttga tttttttgcc attgtaccgc ctccttttat cctaatcatg
    51781 agacattaaa tcaagcttaa gtatctttaa cgttttattt actggaagaa ccaaatccgc
    51841 cttgacgttg agcagtcgtt tgatcttgat ctgcttttaa aaacggcaaa aagatccctt
    51901 ggccgatacg ctcgcctttt ttgatcacta catccttgaa accaaagttg gtgaattgga
    51961 acatgatatg gccttcattt gcctcattat tgtaataatc actgtcaatc acacctactc
    52021 cgtttgtcaa cactaaaaac cgcttcaacg gattgcttga acggttagca agctgcaaaa
    52081 attcatcttc tcccatgtaa gctttgattc cagtaggcac gagggttggt ttcaattgtt
    52141 tttcattttc tgatacatct tttttcaatc catctgcgac tgtttccaac ccctttttcc
    52201 agcctgcttt ccagatactt ggaatcacga cctcttctgc tgcttcaaaa tcatagccag
    52261 cagcatgatg tgtagcgcgc tgcggtagat tgatattttg atctttatat ttagaaataa
    52321 cttcaaatcc tctttttctc accggttt
//
LOCUS       DADVXV010000010        51259 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.010, whole genome shotgun sequence.
ACCESSION   DADVXV010000010 DADVXV010000000
VERSION     DADVXV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 51259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.010"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(53..1558)
                     /locus_tag="KB969_000530"
     CDS             complement(53..1558)
                     /locus_tag="KB969_000530"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBB6868544.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(1650..2240)
                     /locus_tag="KB969_000531"
     CDS             complement(1650..2240)
                     /locus_tag="KB969_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6868545.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            2419..4065
                     /locus_tag="KB969_000532"
     CDS             2419..4065
                     /locus_tag="KB969_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6868546.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            4114..4833
                     /locus_tag="KB969_000533"
     CDS             4114..4833
                     /locus_tag="KB969_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBB6868547.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            5312..6259
                     /locus_tag="KB969_000534"
     CDS             5312..6259
                     /locus_tag="KB969_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868548.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            6271..7191
                     /locus_tag="KB969_000535"
     CDS             6271..7191
                     /locus_tag="KB969_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6868549.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            7232..8689
                     /locus_tag="KB969_000536"
     CDS             7232..8689
                     /locus_tag="KB969_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6868550.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            9034..9648
                     /locus_tag="KB969_000537"
     CDS             9034..9648
                     /locus_tag="KB969_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6868551.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            9641..11365
                     /locus_tag="KB969_000538"
     CDS             9641..11365
                     /locus_tag="KB969_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6868552.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            11362..12813
                     /locus_tag="KB969_000539"
     CDS             11362..12813
                     /locus_tag="KB969_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6868553.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(13286..15439)
                     /locus_tag="KB969_000540"
     CDS             complement(13286..15439)
                     /locus_tag="KB969_000540"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBB6868554.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(15441..16487)
                     /locus_tag="KB969_000541"
     CDS             complement(15441..16487)
                     /locus_tag="KB969_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6868555.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            16637..17926
                     /locus_tag="KB969_000542"
     CDS             16637..17926
                     /locus_tag="KB969_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBB6868556.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            17939..20641
                     /locus_tag="KB969_000543"
     CDS             17939..20641
                     /locus_tag="KB969_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBB6868557.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            20626..21483
                     /locus_tag="KB969_000544"
     CDS             20626..21483
                     /locus_tag="KB969_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6868558.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(21554..22453)
                     /locus_tag="KB969_000545"
     CDS             complement(21554..22453)
                     /locus_tag="KB969_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6868559.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            22622..24793
                     /locus_tag="KB969_000546"
     CDS             22622..24793
                     /locus_tag="KB969_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6868560.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            24861..25202
                     /locus_tag="KB969_000547"
     CDS             24861..25202
                     /locus_tag="KB969_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6868561.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(25478..27232)
                     /locus_tag="KB969_000548"
     CDS             complement(25478..27232)
                     /locus_tag="KB969_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868562.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(27243..28079)
                     /locus_tag="KB969_000549"
     CDS             complement(27243..28079)
                     /locus_tag="KB969_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6868563.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(28081..28764)
                     /locus_tag="KB969_000550"
     CDS             complement(28081..28764)
                     /locus_tag="KB969_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBB6868564.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(28923..30317)
                     /gene="uxaC"
                     /locus_tag="KB969_000551"
     CDS             complement(28923..30317)
                     /gene="uxaC"
                     /locus_tag="KB969_000551"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBB6868565.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(30356..31855)
                     /locus_tag="KB969_000552"
     CDS             complement(30356..31855)
                     /locus_tag="KB969_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBB6868566.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(31848..33269)
                     /locus_tag="KB969_000553"
     CDS             complement(31848..33269)
                     /locus_tag="KB969_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBB6868567.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            complement(33329..34321)
                     /locus_tag="KB969_000554"
     CDS             complement(33329..34321)
                     /locus_tag="KB969_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6868568.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            34553..36751
                     /locus_tag="KB969_000555"
     CDS             34553..36751
                     /locus_tag="KB969_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6868569.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            complement(37209..38081)
                     /locus_tag="KB969_000556"
     CDS             complement(37209..38081)
                     /locus_tag="KB969_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6868570.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            38381..39355
                     /locus_tag="KB969_000557"
     CDS             38381..39355
                     /locus_tag="KB969_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868571.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            39377..40069
                     /locus_tag="KB969_000558"
     CDS             39377..40069
                     /locus_tag="KB969_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6868572.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            40035..41543
                     /locus_tag="KB969_000559"
     CDS             40035..41543
                     /locus_tag="KB969_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6868573.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            41617..42720
                     /locus_tag="KB969_000560"
     CDS             41617..42720
                     /locus_tag="KB969_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6868574.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            42723..44060
                     /locus_tag="KB969_000561"
     CDS             42723..44060
                     /locus_tag="KB969_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6868575.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            44047..44925
                     /locus_tag="KB969_000562"
     CDS             44047..44925
                     /locus_tag="KB969_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBB6868576.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            44922..45845
                     /locus_tag="KB969_000563"
     CDS             44922..45845
                     /locus_tag="KB969_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBB6868577.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            45842..46252
                     /locus_tag="KB969_000564"
     CDS             45842..46252
                     /locus_tag="KB969_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBB6868578.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            46256..47824
                     /locus_tag="KB969_000565"
     CDS             46256..47824
                     /locus_tag="KB969_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBB6868579.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            48064..49482
                     /locus_tag="KB969_000566"
     CDS             48064..49482
                     /locus_tag="KB969_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6868580.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            49494..50804
                     /locus_tag="KB969_000567"
     CDS             49494..50804
                     /locus_tag="KB969_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBB6868581.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
BASE COUNT        16518 a         9055 c        10466 g        15220 t
ORIGIN      
        1 tcacagtccc tttttttctt agaaatggga aaccactagt atataaatac cattattctt
       61 caatcaaccg cttcacgatt gcataatccc cttcataagg ttcatctaca ccattgattt
      121 tttgataggg atccacgcct tttcccgcaa taacgactga atcttgcgga gcgctttctg
      181 ctaaagcgcg tcgaatcgct tcaggacgat ccatttcata atgaacgatc aaatctggat
      241 tagtaattgc ttcattgatt tcttccgcga tttttttcgg atcttcaaat gctgggtcat
      301 ctgccgtcaa aaaggcgatg tcagctgttt ctgatagcac ttttccaaaa tcatgtcgac
      361 gggagattgc tttgtttcct gggctgccta atacaacaat tacacggcca tctggatgtt
      421 catttttggc aaattccagc aatgttttca agcttagata attatgtgca tagtccacat
      481 agacatgcgc tccattggat tggatcaatt gatccattcg gcctggtaca cgagcttctt
      541 ttaatccgtc ttgtgcatct tgactggagg cacctgttag tgctgcggca atgatcgcac
      601 tggctgcatt ttcttggttg aatcctccag ccagcaaaat atcataagca gtatcgcaga
      661 tagctaagcg atcttcatga gaagataaag taaaaccgtg agtaccttta tctgaacgga
      721 tcacttgata attgctttct tccgaacgac cataagtgat cgttggaatc tggaatagat
      781 cggctgtttc cctaagtaaa tcaaaatagt cactttcatg atttaaaaca actgtttttg
      841 aattcaagat caattgtcgc ttgcaataga aatagtcatc aaatgtcgga tgttcgatcg
      901 gactgatatg gtcaggcgag atattcaaga agattccgac atctaaagtc aagccgtata
      961 cgcgttgtgt tttgtaagct tgtgaagaaa cttccatcac tagatgagtc ataccatttt
     1021 caactgcttc tgacatcata cgatataaat ctaatgactc aggcgttgtc aaatgggatt
     1081 tgaaatatgt tttgccatct aacgttgtat tcatagtaga aagcaatgct gtttttttat
     1141 ttgttgtgtg atccaagatt gcttttgtaa agtacgcagc agttgtttta ccttttgttc
     1201 cagtgaatcc gatcactttc aatttatttt gcggatagtc gtaaaaagcc atagcaagaa
     1261 gcgccattgc tttacggata tccgttacga tgattcctac tgctgaattt tcgtatggtt
     1321 gttctgatac ataatattga ataccctgtt cgattgctga atccaaatat tcttctttga
     1381 aattcattcc tttacagaaa aacaaagtag aagcatcagc ttttcttgaa tcataactta
     1441 actgaagaaa ttcagctttt tctggtacat caagatgcca gcctcttgtt gaaacaaatt
     1501 cttttaatag attttctttt aatagtaaat gacggatgtc ttctaaagag aagctcattg
     1561 attgatccct cgctttattc aatttcttgg tttattatag cacactcttt ttaatatatc
     1621 gtttgtttcc gctatgacaa aatccagctt tattcaaatt ttcttgacac aggggacaag
     1681 cggatgagta ttttcataaa caatgaactg actgtaatag ataggagaac gaatagtgtc
     1741 tccaacaatc caaaaacata ataattcaaa aagacgataa gactattggt aagtaaaagt
     1801 ccttgcggca ttggaagccg aaaaaatttg tggaaaataa tcggcggtat cgttataccg
     1861 ccatttgagg ccccgactgt gtacaatgtg taaaccccaa gactgaacaa aagacttcct
     1921 gaaatcagtg aaaagaaatg tgaggagatc atttccactt ttggaacaat ctctaaaaca
     1981 acaggaaaaa gcagacttcc cgctacagtc ttaaaaaata ctgattttcc taataggaca
     2041 gcggctagaa gcagcatcat aagattgatg ctccaaacag taactgagcg ttggatagaa
     2101 aaggccgttt caactaaatg tccgatggcg cccactccgg cggaagctat atcgtgaggg
     2161 agcaagaacc aattcaatcc aactgtgata aagaaaagac ctaaaaatat aacgggtagt
     2221 ttttttattt cttgtgtcat tgatatctcc tataaatgtt agccataaaa ggctgtatat
     2281 ttctttactt taccaaaaaa acgaaaccga attcaaaaaa acaattgttc ttataaaagt
     2341 tatataaaat cgattgccag tttctgtttt accaattaaa atgatagtaa tgttttgtag
     2401 aaagttggaa tctgaccgat ggataatcaa agaaaaccag cattagatca attaacaccg
     2461 caagaaaaaa tggcacgagg ctctgcttgg atgaccgcca gtaatatcat ttcaagattg
     2521 ctaggcgctg tctatatcat tccctggtat gcttggatgg gcgaaaatgc taaggctgcc
     2581 aatggattat tcaatatggg atacaatata tatgcattgt ttctactgat ctctacagca
     2641 ggaatacctg ctgcgattgc aaaacaaact gcacgctata attcattgaa tgaatatggc
     2701 acttcacgac gattatttat ccgtgcatta cagatgatgg gcgggctagg cctgttgttt
     2761 gctttgttca tgtacatcgc ctctccttgg ctagctcatg cttctggtgg cggagaagaa
     2821 ctgattccaa cgatgcgttc tttgagtatc gctgtattgg tttttccttg tatgagtgtg
     2881 atacgagggt attttcaagg caatcaagaa atgatgcctt atgcgctgtc gcagattgta
     2941 gaacaggtgg cacgtatttt ttatatgcta ttggctacat tcatcatcat gaaagtcatg
     3001 gatggtgact atgtgacggc ggtcacgcaa tcaactttcg cggcatttat cggtatgcta
     3061 gcaagtattc ttgtcctttt gtattttttg aagaaacatc aagcgtatac atcggcgttt
     3121 attcactaca gcgaaaacaa aataaatatt gcaacgaagg aattgttgtt agataccgtt
     3181 aaagaagcga ttccgtttat tattgtgggt tcaggggtaa cgatcttcaa attagtcgat
     3241 cagttcactt ttatgaagat catgtctgca tccaccgagt attccaatgc acagttactg
     3301 gatctttttt cgatttttag tgccaatcca gataagttga cgatggtagt tattgcattg
     3361 gcaacatcga tcgcgtctac tgggttaccg ttgattacag aagctgttac gttgaaagat
     3421 cgagtaggtc tggcaaaatt gacaagcgga aatttacagt tgttttcatt ttttatgttt
     3481 ccggcgacat ttggtgttat gttacttgcc tatccgctaa atacattatt ttatacaccg
     3541 gattctctag gaagtaatgt actgatccaa gcaagttttg taggactctt cctaggacta
     3601 tatatgctag tttccaacat gctgcaagga atgtttgaaa acaaggcggc aattaattat
     3661 ttggttattg ggtttctagt gaaactcctt cttcaatacc cagccattcg tttatttgaa
     3721 gtatacggcc ctttattggc gacaatgatc ggatttgctg tgtcttgtac cttgatctta
     3781 aagagaatcc atgaagtagc ccgctttaaa ccaagttttg tctggcgcag gacattgctg
     3841 atctttattc ttaccttgat tatgcttttg gcttcgtgga tcacaaagat gatttttggt
     3901 gcttttttaa acgaagatag caaattccag tctctattgt tgattcttgt agtagcaggt
     3961 ataggggctt tagtgtatgg ttatttagct ttgaaaatcc gcttggcaga aagactacta
     4021 ggaccaggaa tagcgcgttt acgacataaa ttaaaaataa aataagtgaa tcagaagagc
     4081 tagattgatg ctcttttgaa atgggggaaa cgcatgcgtt tagataagtt tttagcagat
     4141 atgggacttg gcagccgcaa agaagtcaaa ggattgatca aaaaaggaac gatcgaagtc
     4201 aatggacaag tggtgaaaag cgataaagcg caagtaaatg aattcgaaga tgcggttact
     4261 tatttaggag aaatcattac gtatcaaaaa gatttttact acattttgca taaacctgca
     4321 ggagtcattt ctgctactca ggataatcat gatcaaaccg taatcgattt attggaagac
     4381 caggattatc gggaagatct ttttccagtc ggccgattag ataaagacac agagggcctc
     4441 ttgattttaa cgaatgacgg ggtgtttgcc catcagttac tatcacctaa aaaacatgtg
     4501 gagaaagaat atctagctga ggttagcggt ataatgacag aagaagatat ccgtttattt
     4561 gcagaaggac tgattattga tggcgatgag cagacattgc cggcaaaact ccaaattgat
     4621 caagtagatc aagagacaga aacttcaatt atccgtctga ttttgcatga aggaaagttt
     4681 caccaagtta agcgaatggt caaagcagta ggaaaagaag tcttatattt aaaaagaatc
     4741 cgtatgggaa aattttggct gcctaaagat ttgaataaag ggcaatatcg acccatgacc
     4801 aaagaagagc tagaacaagt gagagaaaaa taattgaatg gatagctaaa agaataagca
     4861 gagtagttgt agcgccatct gaaaagcaga cttgtccgtc tgactttcgg atggcttttt
     4921 tgtgaaattt cggcttattt ccgtagaagc tacttctgga acaccgtttg ttcggaataa
     4981 gggactgtga caagactttt gttacagtcc ccattgttcc ttgtgactca gagttagata
     5041 gtaaggacac gatctcccta atactcaggc caaaacgctg aattcacaac ctctgataaa
     5101 cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta
     5161 ttttcccgtt tttttctcta atactcaggc caaaacgctg atttcacaac ctctcctata
     5221 ctttgtttca ttttccctat actttgttta tttattctca ttattgaaag cgctataatt
     5281 acgttgcgaa tgaatcgaaa ggggttttta gatgaaaaaa cgaaaggggt tcaatcattt
     5341 ttttatgaat ctatggcgtt ataaagcact tgtcctgatg gctgtaccgg gtatgctttg
     5401 gatgattttt ttcttttaca tacctgtaat ggcgaatgtc gtagcattca aaaattttca
     5461 tatttcagca gatgggttct tggctagctt gagggaaagt ccttgggtgg gttgggaaaa
     5521 tttcaaattt ttattttctt cggatcaagc atttctcatc actaaaaata caattttata
     5581 taatgtagca tttatccttt tgaatctgct gatctcagtc gtatttgcaa tcattatgag
     5641 cgagttgaga aataaacgac tcgttaaagt ttatcaaacg atgtccttac taccttattt
     5701 tctatcttgg gtcattatca gttactttgt ttacgctttt ttaagtcctg acaaaggaat
     5761 attcaatcag tggatcactg gacatggagg agaagctgtc aattggtata atgaaccgaa
     5821 atattggccg tttatcttgg tgttcattgg tacatggaaa gggattggtt ataacagcat
     5881 tatttacttt gcatctgtta tgggaatcga tccgacttat tatgaagctg ctatggttga
     5941 tggagctagc aaatggcagc agatcaaaca tgtgacgata ccacaactta ttccactaat
     6001 gacgatttta acgattttag ccgtaggaaa cattttccga gctgattttg gcctgtttta
     6061 taacattcct aggaattccg gtgcattata tgatgtgact caagttttgg atacgtatat
     6121 ctacaatggc ctgacatcca caggagattt tggtatgacg gctgctgcag gactttacca
     6181 atcagttgtc ggctttgtct tgttgatgat cacaaatacg atcgcccgac gttttgatag
     6241 cgattctgca ttattctaag gaggaaaaaa atgaaaaaaa agaaagtgga gagagtccaa
     6301 gtccgctctt tcaataagac ggctaatttt ttctctaata taatgattgc actctttgct
     6361 atttcctgta ttttgccatt tatatttgtt atcgccatct cttttaccga tgagtccata
     6421 ttgtcgactc acgggtacag tttttggcca gaaaagttca gtatatttgg ttatacgtac
     6481 ttgttcgacc agatgcagga taaaattttc caagcgcttt tcgtcactgt acttgttact
     6541 gttttaggta cactgatcaa tagcacggct acttctttat atgcttatgc gatttcacgg
     6601 tcaaactttc cattccgtcg tttttttacc gttttttgtt tgattacgat gttgttctca
     6661 ccagggatgg tggccaatta tcttgttatg acaaatcttc ttcagttaaa agatacgatt
     6721 tgggcattga tcttgccaat ggctgtcagt cccttcaata ttattgtgat gcgcacattc
     6781 tttaaacgtt cggtctctga ttcgattatt gaatcggcac ggatcgatgg agctagcgaa
     6841 ctgcgaatat ttgttcagat cgttttaccg ttagctgttc caggtattgc gacaatcagt
     6901 ttatttgccg cattgggtta ctggaatgac tggttcaatg ctttactata catccaagat
     6961 gataagctag ttccactaca gtatcttttg atgaaaatcc aaagtaatat tcaatatctg
     7021 acacaaaatt caggagcagg aagccaattg acaggcggat tagcctcagt tccaggagaa
     7081 tctgccagaa tggcgatcgt agtcatctcg acgttgccta ttgcgatcag ctatccattt
     7141 ttccagaagc attttgtcaa aggtctaaca atcggcggag taaaagaata aagaaacaaa
     7201 aatataaatc ataaaattag gaggaagaaa aatgaagtta tggaagaaac tagcctttac
     7261 aggtgtttca gcgttgttgt tgggaacatt agcagcatgc ggaggttctg gttctaaaga
     7321 ccaggcagaa gctagcaatt cggacacttt gcagatgtat caaatcggag ataaaccaga
     7381 taatttcgat caattgatgg aagtagcaaa caaacgaatc gaaaaagaga tcggtgtaaa
     7441 agtcaatatc aattacattg gctggggcga ttacgaaaag aaaatgaacg tcatcatttc
     7501 ttccggggaa aattatgata tcgcctttgc gaacaactat gtttccaatg cccaaaaagg
     7561 agcctttgct gatttgactg aattagcgcc taagtacgct gaaaaagctt ataatgattt
     7621 agatgaagca tatattaaag gaaatctggt caatggaaaa ttatatgctt tcccagtcaa
     7681 tggaaatgtc tttgctcaac aagtacttac ttttaacaaa gctttactag ataaatacga
     7741 tctttcaatt gatggaatcc aatcttacgc tgatgcagaa aaagtcttga aggaattcca
     7801 tgaaaaagaa ccaaacacgg cagcttttgc cattggacaa ggcttcaaag tccaagggaa
     7861 ctttgattat cctttaggga atacgttacc atttgctatt gatctggatg gagatgattc
     7921 gaaaatcatc aaccaatacg ataatgaaac gtatatcgga ctgttacgta caatgcatag
     7981 ctggtacaaa caaggactca ttccaagtga cgctgcaacg agcaataagg attatccact
     8041 agaaggaaat acttggctaa tgcgtggaga aacacaagga ccgtatgatt atggcgatac
     8101 aattttgaca aatgcagcaa aacaagaact tgtctcaaaa gcaattactg ttccactaaa
     8161 atctacagct caagcacaaa tggcaaattt tgtcgtatca aatacttcaa aaaataaaga
     8221 aaaatcagta gaacttctag ggctgcttaa cagtgatcca gaattattga atgggcttgt
     8281 ttgggggatc gagggagaag catgggaaaa agtcgatggt tcagatgata aaatcaaatt
     8341 gctagatggt tatcagccaa atacacatat gtctgcttgg aatacaggaa acaacaagat
     8401 tctatataca caagagtcta ttacggatga catgattgcc aaacgtgatc aatcgattgc
     8461 tgatgcagaa acttcaccga ttttaggatt cagcttcaac actgacagtg tcaaaacaga
     8521 attaagtaat atttctaatg tcatgaatca atatttagat ggattgaata cagggactgt
     8581 tgatccagat gaaacattac cgaaattgaa agacgctttg gacaaggctg gctatgataa
     8641 ggtattgaaa gaaatgcaaa aacaatatga tgagttccga caagaataat aatgaataaa
     8701 gacaaagggg ttgtgacaaa agacgtgtca caacctcttg ttccgaataa acggtgttca
     8761 aaagccagtt tctcggtatt aagctaaata tatgtaaaaa tgtggaaagc catattcaca
     8821 aaatttttct tactactcga aactaagcgg ctatttcaca aactcttggt aaacggtgtt
     8881 caatcagcta accctcggta ttcgctcaca aaacgacaaa atatgaggaa ctatttttcc
     8941 gtttgtttct ctaataatca ggtcaaggtg ctgattgccc aacctttttt tgtataatga
     9001 gaaagtataa acttaatgtt tggaggagaa gatatgttag ggaaggtttt ggaagagtta
     9061 tttatccgga tctgggtcat tataaaacta accttgtatt tctggatata tacatttgcc
     9121 ggcgggatca tctttggatt aggtgcggca tggaaaacag tcaatgaact attttatttg
     9181 tacggattcg agtataaaga aatcacaata aaaagaggct ggaatatata taaaagaaat
     9241 tttttaagag gcaatctgct atttagttta tttttatctg gtactgcttt attgagttac
     9301 aatttatatt tatctgttca aatcaaaggg ctcatttttt tagctattga ttttatttta
     9361 ctttttgcct tgctctgcct atttgctact tatcaataca gtatgatttt agatagtgaa
     9421 tatacgatct ctgttcctaa tctgctaaag ctaagtttta tttcggtttt ttccagcttt
     9481 tcgtcttttc taaaaataat tattggtagc ggtataattt taggcgtgac ttggcaattc
     9541 aaaggattga tcctgtttgg tgtcattggt cttttgacgg tttggaatgg tacgatgaca
     9601 acacattggc gtgaagaatt agataaacag ttggaaagtt atgaataagt ttcggattct
     9661 attttcaaaa ggaaccttac taaatcgtct gttgcggaaa tacgcggtta tcatgatcgg
     9721 tgtaacgatg actgctaccg ttatttttag tatccatact tgggaacaaa atcaaaaaca
     9781 ggcagaaaac atgacaagtg atgccgttca aagcacaagc agaatgctga atgataaaac
     9841 aaccttgagt aggatcatca aaaaccagct tgtagggaat tccgaaaaga tcgaaaatgt
     9901 gacgacctac ttaacaaaac ccatagatca gtatctgatg tatgtatacg aacagcaaaa
     9961 cagtaccgat gaattagttt ctttcccaaa tcaaatcaaa gatctctacg caaattatga
    10021 agaactaagt gcgatatata tcgtgttgaa tcaactaccg gagtattatg aatcttctag
    10081 agaaaacaaa ggtggggaaa taaaaaaggg gacaccaaaa ttactagacg ccttttatat
    10141 caagttgcct atcacacaag gaggagctga gtcaggaagt atttttattg gttttcaaaa
    10201 gaaagaacta gatatgattt tagaaaatct aacgtcattc aatggactct ctttatacat
    10261 gatttctgga acgacaaatc gactatacac attccatgat aataaaatag ctaaagaaac
    10321 gtttgaaaga caagaaatga tcatcacaga gagtctgaag aaaaattcac aattgccgat
    10381 tgacgatctg gaaaaaaaca attttgttca acaccaagaa ctgtctgatg attatcgtat
    10441 attagctgta ctagataaaa aaagtgtaaa aatcgaaacg ggaaaaaatc ttgccccgct
    10501 gatcattggt atcattattt tagacaatat actgcttatc tttctttata aaacattcaa
    10561 acgatattca cagcaagtat ctatcgtcat gcaggccatg gatcaaacag cagcagggaa
    10621 tttagagacg cggatcgaca taacaaacac ggaatatgaa ctgaaggaac tttcaatcgg
    10681 tatcaacgaa atgttggata gcatcaatca gtttgtagaa gacatctaca aattagaaat
    10741 caaacagcaa gacgcacata tgcgggcgct tcaagcacag atcaatccac actttttata
    10801 taatacatta gaatatatcc gaatgtatgc aatcagcgaa ggaagtgaag aattagcaga
    10861 tgttgtgtat gcgttttccg ctttgcttcg aaacaatacg aatcaagaga aaacgatcac
    10921 tttaaaagaa gaactggact tttgcgaaaa atatgtctat ttgtatcaaa tgcgttatcc
    10981 taatcgagta gcctatcatt ttatgatcga tcctgatttg gaaaagatcg aagtacctaa
    11041 atttgtgatc cagccattag ttgaaaatta ttttaaacac ggtattgatt ttactcgatt
    11101 cgataatgcg ctaagtgtca aagtcttgca ggaaggcaaa cgggtaagga tcatcatcaa
    11161 agataatgga aaagggatga ctgaaaaacg gctaaaacag attgaagaaa aactgtctca
    11221 tcctaaagtg gaacttcacg gttctatcgg tctgcaaaac gtgaatgaac gtttacgtgc
    11281 cagcttcggc agcagttatt atatgtcgct tgagaataat gagacaggtg gactgaccgt
    11341 ttctattaca ttcaaggagg gatgagcgtg tatcaagtgt tattggtaga tgatgaatac
    11401 atgattttga atgggttaaa aaagataatt gattggcaaa gtttaggctt tcaaatagta
    11461 gcaacagcag agaatgccaa agaaggacta gctgtacttg aacagcgaca gattgattta
    11521 gtagtaacgg atgtgacaat gccagaaata aatggactgg aatttattga agcggctcaa
    11581 aaagaacgtc ataattttga atttatgatt ttatcaggat accaagaatt cgattatttg
    11641 aaaggaggta tgcaattagg cgccgtgaat tatttgatga aacccgtgaa taagttcgaa
    11701 ttggttgaaa gcctcaagaa aatcaaaaca cggttagatc agcaaaatga acaaaaaaat
    11761 caacaagaaa tctatcaaga actgttattc agtcaatggt tgaatgaaga attggatgaa
    11821 ataagtgaag aagaaataat aggacaaata agtgagaagc agcataggat agtattgatt
    11881 caactggcaa gaactcatga tactcttatc aatagatggt tgcaagaacg gcaacaaatc
    11941 ttttactatc aacgaaatta cggagaccgt gtattgatca cgttgttgtt ggaggcagat
    12001 gaagttgatg gcttctgttg ttttgttcaa gaaaactttc ctgatcagga atggctgatc
    12061 agtatcgggg aagagacaga ttctttggac aaaatccctg aaacattcca acaagcgaaa
    12121 gacaatctac agttgcatca attttatgga gataaagacg agcatgtttt ttacgcagta
    12181 caagcagaaa caaaagatca aaccatcgat ttttcaagtt tcagacgcgt gctgcaaaat
    12241 aaacaattgg aagtcgctca aaaaatgatc actgattttt ttgaacagtt tcagttagca
    12301 gccatgatgc cggaagatat acgatattcc agttttttac tgtttatgga gattcaacgg
    12361 gaattgattg atctggaaga tgaggaatat ttacaaggaa tcgaaaaaat ccatcaggca
    12421 aaaacggtgc aagaacttca gcagctactt ctgtcattca tcaaaaagca tcagagacag
    12481 aaaaagtaca gtgacaatgt ggaaaaagta atcgtaatcc tgcaccagca ttatcaagaa
    12541 ccacttacac tcaaagaagt gtcagaaaac ctgcatttaa atgtcatgta tctaggacag
    12601 ctgttcaaaa aagaaacgaa aaaaagtttt tcagcttatt tgaaccattt acgtatggaa
    12661 aaagcgaaac aactgctttt gcacagtaat caaaacatca atgagatagc aagtgagatt
    12721 ggctacaaca acaccacgta tttctctaaa ttattcaaga aaatcgtcgg cagatcccct
    12781 aaagagtacc gagaaaacag tggagaatca taaaaaaaaa agccaatgta atgaaataac
    12841 ttataaaaaa ttgtctagaa atctaatttt gggctgttct tattacttga ggcaaggcag
    12901 ctttttcatg acctctcgat aaacggagtt caaaagccag tttctcggta ttaagccaaa
    12961 tttatgcaaa aatgtggaaa gccattttca caaaattttt cttaatactc gaaactaaac
    13021 agctttttca cgacctctcc actaaatggt gttcaatcag ctgaccctcg gtattagctc
    13081 aaaaaatggc aaaatatgag gaactatttt gccatttgtc tctctaatac tcaggtcaga
    13141 acgctgattt cacaacctct caataaacgg tgttcaaaag cttgcatctg cggtaataag
    13201 accaaccaaa cgaaaaatat gaggatctat ttttgcttgg ctgttcttat tacttgatgc
    13261 aggacagctt tttcacaacc tcttgttaat tatagtttga taaggaaaaa ggcaaatctt
    13321 ttgcttgata tttcttaggg tgagggatga tccctaattg gtaagagatc gtgccgcctt
    13381 tcagcaaatc ttgatgggta aaatataatt tcgtatattc tctgtccatc cgtttgattt
    13441 tatggataaa ttgttgctgc ggccgattag gcgttgcttc aatcgtcaat tcctttccat
    13501 ttgacaaaag caaaacagcc ttgtcaatta atggcatacc gataacatat tcaccggttc
    13561 caggcgtgac aggataaaat cccagactat tgaagatata ccaagcggcc atacttccat
    13621 tgtcctcatc tccagggtaa cccattggag aatcgtcgaa ggtctgagtc atcaactgtt
    13681 taagcagtgg ctgtgccatt tcaggttgtc ctatataact gaacaagtaa ggatagtgaa
    13741 aacttggctg gtttgaaata gctaattgtc caaattctat cgcggccatc tcactcattt
    13801 cgtggatctc aaaaccatat cctcctgggt caaacgttgg gggctgattg cacagctcaa
    13861 tgagtttttc tttatatctc tcactgccac catattttcc gatcagtcct gaaaaatcgt
    13921 gataaacagc aaagctgctt tgccaagcac ttccttctgc ataatcttgt ccccaacgat
    13981 tagctgaaaa tggttctctg aacttgccat ctttatcttt tgaacgcata aatcctgact
    14041 catagtcaaa gatattttga tagttcaatg attgctgctg atatttcttc gtcatttcct
    14101 cttcttctag taccttggca acttggctaa tacaaaaatc gctataagca tagtctaatg
    14161 tgtgattgac tgattcgtgg tagtgattag gaacatagcc atatgtcaag taatcttctg
    14221 ttccttggcg tccataattt ggatgtttgc tttgaaccgt agcacctttt tccattgccg
    14281 ttagaaattc aggcatcaag tctcgtcgga tatcttttac agcagcatct gcaatgaccg
    14341 catcgatcaa tgtcccaggc ataagtccac gttcatcagg agacagccat tttggcaaat
    14401 agccactttc tctatagctg ttcaaaaaac cttccagcat ttcttcgtat ttttctacag
    14461 caatcaaaga ataaagagga taaaccgttt tatacgtatc ccaaaaccca ttatttgtat
    14521 agagaacacc aggttttata gatcgactag tcgtatcata gtggattttt tgcccactag
    14581 gatcaatttc ataaaatgtt tgtggaaata aaaacacccg atataaatta tgataaaacg
    14641 tccgcaattg ttgttgatca tggtgtgtga gctgtatacg atcaaaatag gactgccatt
    14701 gttcttgact gtgagcaagg taagtctctt tgctttggtt ttgttctagt tccaggttat
    14761 aagctgcttg ttccgagctg ataaaagatg tcccaaatcg gatagtttgt ttttttgtct
    14821 gttcaaaata caacgggatc gagtcgctat ttttgttgga aacagctaac tcatcaattg
    14881 ttaaaggata ttcaaatctc aatataaaat aaaaagaaaa atcaggatct tctgaaccag
    14941 caaaatgtgt gatttttcct tccactgtgt aaggatctat aacaaagagc tgatggcgtc
    15001 ccggaaagga taaaagtaaa ccgctgtcat ttttgctgta atcaatagat aagattccgc
    15061 catacatgct aggtatcaat gtagaacaga tgccataacg taattgacag atcgacagat
    15121 gagtcgggca aaatatactt tcttctgggc ggtaagaact ttgagcatgg aaaagggtgt
    15181 tctcctgtag ttttccattg atcggcgtaa acagcatatg actgaaatca cccatccaag
    15241 gacttggttg atgggtaaga cggtagcctt gaaaaacgcg gtcatcagga tgaaaccacc
    15301 agctgccgtt ttgatccgta gtttgcggtg caaaataatt catcccaaaa ggaacgccag
    15361 tataaggctg gcagttccca ttagagaaat ttggctgatt cgctgttgca tgtctagtat
    15421 ctatttgacc gatattcatt ttatttctcc tttgttgatt gtcttttgat gaatgaaact
    15481 ggaaatttac tatcggatgg tcgatctttt gtctctaacc aagtgaccaa agcatctccc
    15541 gcaagcttac ctaactgttc aaaatcttgt gcgatggttg tcagtggcgg gtcaacaaga
    15601 gctgctgctt ggatatcatc aaatccgata attgaaaaat cttcagggat atgataacca
    15661 tgctgtctca agagattcat ggtctggata gcgacaacat cgttttcaca aacaaaagca
    15721 gttacttcat acttagtgat ataagaaagc aattcatcta atgtcgcgct tttgtcatcc
    15781 agtgaagtgt ggaaagtcaa accagctttg tccaatgctt caaggtaacc aaggtaacgc
    15841 tgtcgaacgg attgtggatg agtctgcgta ccaaacaaat aagcgatttt tgaatgtccc
    15901 tgttcgatca aataagaggc agcaagcgca ccgccttgga aattatcgga aagaacggta
    15961 ggaaaaggta actcatagat ttttttatct aatatgacga cagggaattc tttcaatgaa
    16021 agctcaaaaa gtaagtcaag atgttgttct gtatcaagag cataataaat caatccgtca
    16081 aattcattga ttagctcttt tgctgtttta ttttgtagaa agtcaagcgt cgtcatcatg
    16141 acatcaatct gtttatcttg catcacaggg ttcaatccct tgctaaaatc accaacagac
    16201 aaatcagcga catatggaag aagaaacaga atccgtcgtg tttttgtagg agaagcaaga
    16261 atctgttccg gagaagcgga tttaacgaaa ctgcctttcc cgcgaacgcg ataaataagt
    16321 cctaattgct ctaattcagt caatgcacgt ttggaagtga ttctgcttac tttataggta
    16381 cgtgaaagtt ctttttcagt tggtagttgg ctgtctacag gtaattcacc agttaaaata
    16441 gccgtttgca aatcattaaa tattgtctgg tacaatggtt gagtcatata aacacctctt
    16501 aatgatatat catattcaaa taataccata atggatgaaa aagtaaataa aaagatattt
    16561 tttgaaagcg tagacataat tggctgtatg aagtataatc tttaaagata tatcaaatag
    16621 aaagaaggtt ttattagtgg tttataaaga tataccaaaa tcggtgcaga aatttatgga
    16681 agatatcaca caaaaatgtg gggatatcca tgcggactgg gcaaagaatt ttacagcagc
    16741 atttgccaat actctgttga caacagtcaa aaagcaaaat gacggaacca cctttttatt
    16801 gacgggagac attccagcga tgtggttaag agactctact gcacaagttc gtccttattt
    16861 agtgattgca aaagaagatg aggaattagc tgacatgatc agcgggttag tcaaaaagca
    16921 atttttttat atcaatatcg atccatatgc gaatgccttc aacgaagaag ctaacggtgc
    16981 tggccaccaa acagatcata caaaaatgaa cgattggatc tgggaaagaa aatatgaaat
    17041 tgattcttta tgctacccaa tacagttggc ctatcttctt tacaaaaata caggaaaaac
    17101 tgatcaattc aatcaatctt ttattgaagg tatcaaaaaa atcttggacg tgttcaaaac
    17161 agagcaagat catgaacact ctccttatac atttgtacga gacacgacaa gaaaagaaga
    17221 tacgctgatc aatgacgggc gaggtgcaaa aacagctttt acaggaatga catggtctgg
    17281 tttccgtcct agcgatgatg cttgccgtta tggatatctg gtaccatcca atatgtttgc
    17341 ggtggtcgtg ttaggttatg tggaagaaat ttttcaaacg atactcgatg ataaagaaat
    17401 tgtacagcaa acacagaaat tgaagaaaga gatccaagag gggattcaga atcacggacg
    17461 aacggttaat caaaaagggc aaacgattta tgcatatgaa gtagatggaa tgggaaacgc
    17521 cacagtcatg gatgacagta atgtgcccaa tctgatcgcc gcaccttact tgggatattg
    17581 ttctgaacaa gaggaagatt atctgcaaac aagaagaaca ttgttgagta aagaaaatcc
    17641 atatttctat gaaggaaagt acgcaaaagg aattggatcc tcccatacgc cagaaaaata
    17701 cgtttggccg attgcattag ctatggaagg aatgacaacg tcagacaaat ctgaaaaaga
    17761 gcggatattg aatttacttg tagcaactga cgcaggaaca caccttatgc acgaaggatt
    17821 cgatgtgaac aatcctgaaa attatacgag agaatggttt tcttgggcaa atatgatgtt
    17881 ttgcgaatta gtcatggatt actttgatat tagagtagaa aagtaggagg tatcgtaaat
    17941 gaaaaagaaa gtatatatca tttctcatag ccactgggat cgtgaatggt acatggctta
    18001 cgaacagcat cacatgcgac tgattgaatt gatagacgat ctactagagc tatttgaagt
    18061 tgatccgtcc ttcaacagtt ttcatttgga tgggcaaacg attattttag atgactatct
    18121 tcaagtaagg ccagaaaaaa gacaggcaat ccaacaagca atcaatgaag gaaaattgag
    18181 aattggacca ttttatatct tgcaagatga ttttcttatc agctcggaat cgaacgtgag
    18241 aaatatgctg attggcatgg aagaaagccg taaatgggga acccctgtca tgttaggcta
    18301 ttttcccgat acatttggaa atatgggaca gacgcctcaa ttaatgaaac aagctggtat
    18361 ttcagcagca gcgtttggcc gtggtgtaaa accaattggc tttgataatc aagttttgga
    18421 agcagaaaac tattcttccc aatactcaga gatgtggtgg aaaggccctg atcaaacagc
    18481 aatctttggt ctgctatttg ccaattggta tagcaacggg aatgagattc cagtagaaaa
    18541 agaagcagct cttgcctttt ggaagcaaaa attagcggat gcagaacaat atgcctctac
    18601 gaaccactta ttgatgatga atggtgttga tcatcaaccg gtacaaaaag atatatcaaa
    18661 agcaatccat ctcgcaaatg aactgtttcc agattacgag tttattcatt ctaattttac
    18721 tgactatctg gaagcagttc aaaaagatgt gccagaagac ttaggctcag tagaaggaga
    18781 attgacaagt caagaaacgg atggctggta tactttagcc aatacagcat ctgctcgggt
    18841 ttacttaaaa caatggaata ccaaggtcca gcgacagcta gaaaatatta cagaaccact
    18901 tgcgacgatg gcttatgaag ttagtggaaa ctatccccat gatcaattag attatgcttg
    18961 gaagacatta atgcaaaatc atcctcacga cagtatttgc ggttgttcag tcgattctgt
    19021 ccatcgggaa atgatacctc gttttgaaaa agcagatgaa gttggaaagt atcttgcaca
    19081 agattcctta gaacagctga ccgcagcaat cgatacgacc ggattcccaa aagacagctt
    19141 tccatttgtc attgtaaata ctgcaggaat ggataaaact ggtgaagcag aaataaccat
    19201 cgaattagaa agaaaaagat tcgctgaagg aatacctgaa caactatatc aagagttaga
    19261 aaatttgcct aaacgtaagt atcatgtaga aacaaaaagt ggggccacta taccagctat
    19321 tttatctgaa gaaactgtcc aatttggtta tgatttgccg aaagaccgtt tccgtgtgcc
    19381 atatatggca agaatgatca aagtgacttt accattagaa aacatgccag cattttcttg
    19441 ggaaacattc gcgcttgtag aaggggaagc gaaagcagaa gaaaaggaaa caatgattca
    19501 tcagagtgga cgaatcatcg aaaacggccc tctacatttg acgattgaaa aaaatggtac
    19561 cattacaatg gaagatcgca aaaacaaacg aaagttgaat aatctgcata tttttgaaga
    19621 tatcggcgat ataggaaatg agtatatctt taaacaacct ttctgtgatc agccaatcct
    19681 atccagtaac aaagaaaact ctgaagtaaa agtattagta gatacaccgg aaatagcaaa
    19741 aataagtatt ctacaggaaa tggaaatccc tgtttctgca gacgagcgtt tagaaaaaga
    19801 acagcagatg gttgtggaat ttcgttatcg aaaagcagaa cgatccaaag aaaaacgaat
    19861 ccttcaaata aaaacaatca tgacaatcag aaaagatagt aaaaaaatcg actttgaaac
    19921 gactctcgac aatcagatga aagatcatcg cttacgtgtc ttgtttccta caaagttaca
    19981 tgtggaacat cacgaagcag atagtatttt tgaagtggtg aagcgcccaa accatgtgtc
    20041 taaaagttgg gaaaacccca cgaatccgca acatcagcaa gcatttgtca atattcatga
    20101 tgaagagtac ggtgtaacag tcggaaactt tggtttgaat gaatatgaag taacagaaga
    20161 cggacaaatc gcagtgacgc tacttcgcag tgtgggagaa ctaggcgatt ggggatattt
    20221 tccaacacca gaagcacagt gtctaggtga gcatcggttc aattacagca ttgaactaca
    20281 tggaccagaa gaaaaattct ctacttattt gcatgcatac gcagcacaga ttcctttttc
    20341 cactcaacaa atcaaacatc atgaaggaac attgatttca aaacaacaat atttaacgat
    20401 aaaaagtgaa acgtttgcaa ttacagcttt gaaacgcagc aagtttagtg ataaagtagt
    20461 agtaagaggt ttcaatatgt ctagtcattt agaaaaattg gaaataacta aagacaatgg
    20521 aaaaactgtc atattgaatc tgcttgaaga accaacgaag caagcggttg tcccaataat
    20581 ccaaccttat gagattcgga caatcggatt cgaggaggaa aacgaatgta tggcggaata
    20641 gaagcaggcg gaacaaaatt tgtgtgtgcg gtttcagatg gtggagaaat tttagaaaaa
    20701 ttaagtatcc ctaccacaac accagaagaa acattggatc aggtatttga attttttgat
    20761 cgttatgaat tgaagggaat cgggattggc tcattcggcc cgattggtat cgacaaaaca
    20821 aaagataatt acggatacgt tttggcaact cccaaaaaag ggtgggcaca attcgatttt
    20881 cttggcacaa tcaaggaacg ctacaatatt cctgctgctt ggacaacgga tgtcaatgct
    20941 gctgcatatg gggaattgaa gcaaggagca gcacaaggaa aaaatagttg tatttacctt
    21001 accgtgggaa caggaatcgg tgcaggtgtc gtgatcaatg aagaaatttt ttcagggatc
    21061 gcacatcctg aaatgggaca tatttgggtg aaacgccatc cagatgacca ttatgaaggt
    21121 acttgtcctt atcataaaga ttgtttagaa ggattagcag caggaccgtc tattgaggca
    21181 cgcacaggga tcaaagggca agatctgccg caagatcatc ctgtttgggc tattcaggct
    21241 tattatattg ctcaagcact gatcaactat acgttgacgt tagcacctga aaagattatt
    21301 ttaggcggtg gggtaatgaa tcaggatcat ctccttcaaa aaatccgtca gcaatttgtt
    21361 gaattgatgg gtggttatat ggaaacacct caagtaagtg aatatatcgt tcgttgggga
    21421 ctgccgaatg aaagtgggat tatcggtagt ttgctgttag cagaacacga acatcaaaag
    21481 taagcagaca aattacacaa aaagaacaga gtcttatcat tatctgctga taagactctg
    21541 ttctttttta tttctattcc cataatccag gtaaagcttt accgactatt ttttcttgag
    21601 taaatggatg gatcatgtgc agttctaatg catggagcat cagtcgttca gctgttctat
    21661 tttggtagag agggtctcca acgatcggat gtcccttatg agctaaatga actctgatct
    21721 ggtgtgtacg tccggtttcc aaaacacaat agacttgtgt ttgttcagaa agtactttgt
    21781 tgacagtgac atgtgtcaag gcgctctgac catttttatc atctacgacc ctttttctcc
    21841 gatcatggcg atctcgtcca attttattgg tgatggtcat atctttggca atttctcccc
    21901 atacgatggc ttgatatctc cgatagatca ttttttgttc caacattctt ccaagtatcg
    21961 gcaagacaaa tggatttttt gcaaataaaa cggcaccgct tgtttctttg tccaagcggt
    22021 ggacaacgta aggtcgttgc tgtttagtgt cgagataagc agctaaatga ttgagtaagg
    22081 tactgttttc tgtcggttca tttggatgag tcttcattcc tgcaggctta tccactataa
    22141 tcaaatgctc atcttcatat aaaacacgga tgtgcttcgc atctcctaat tgaacttctt
    22201 gataattata atctgtttct tcgaataaca atgtgatctg gtcattgccc tttacttcat
    22261 gatggaacaa agcaggttgt tgattgatcc aaacgttttt acgtatacgc aaaaagtgtc
    22321 gaacctttct aggaactaac cattcctttt caagcaagtc gcgaattgtt gtttcaggat
    22381 ggttcatagg taaagtgatc gtgattttca caagtgtact cctttcagtg caatcgcaga
    22441 ctaattgtac catttttaaa acatatttaa gaaaaaactt acatttttct gttcattctt
    22501 atgttactct acttgcacta acgtaaaaaa acatattgaa ctacaactta agcaggaaga
    22561 aaacactctt tcactatggt aaaataagac gattgaatca aatagacagg agaagaagca
    22621 aatggatttt caaagcattt tagaaaagat aaaagctgct ttgatcagtt tttggcgttg
    22681 gatcagacca tatctcggac aattccatcg atggcgaaag cgcatctgga aaaaatatca
    22741 tgtgaacaaa ttgattttgc tgattggttt gatctgtgtc ttagtgacaa gtatctacct
    22801 ctttatttta gcaaaacaag caaatgtcga aacgttaaaa tcaggattaa gccaatcgac
    22861 agtcatttat gataagaaaa acgaagaagc tggcacactg tacgcccaaa aaggaacata
    22921 tgtagaatta aacgcgattt ctccctatat ccaagatgca gtaatctcga cagaagatag
    22981 gaatttttac gagcatcacg ggtttgatat caaagggatt gcccgtgcag cagtccgaat
    23041 ggtcttgtct ggcggaacat cagggggcgg aggaagtacg atcactcagc agcttgccaa
    23101 aaatgcgtat ctgacattag accaaacgtt tgatcgaaaa gcgaaggaat tatttttggc
    23161 aatcgagatc gaaaagaagt acagcaaaga agaaatcttg accatgtatc ttaacaatgc
    23221 ctattttggc aacggggtat ggggtgtcca agacgcttcc agaaagtatt ttggagtaga
    23281 tgcaacgaat gttacgctgt ctgaggctgc tactttggca ggaatgctga aaggtcctgg
    23341 tatttataat ccgatcgatc acccaaaaaa tgcgaatgat cggaaaaaca cagtactaag
    23401 tgtaatggaa gaaaacggaa aaatcacaaa agaacaagaa caagcagaaa gccagacaga
    23461 tatcagcgcg tatcttaatg acacatacga taattcagat tctggttatc gttatcctta
    23521 ttattttgat gcagtgatcg atgaagcagt taacgagtat ggtcttgatg aagaagatgt
    23581 catgaataaa ggctataaaa tctatacagc tttagatcag gattatcaaa agcaattaga
    23641 agctacttat caaaacagtg cattattccc agcaaatgct tcagatggtg ccatggtcca
    23701 atctgcttca gtagctttag atccgaatac aggtggtgta caagcactag taggacgaag
    23761 aggagatcat gtctttagag gattcagctt tgctacacag atgcgtcgtt caccaggatc
    23821 aacgatcaaa ccattaagcg tatatacacc agcactggaa gctggataca agccttccag
    23881 tatcttgaaa gacgaaccgc aaagttatta cgatgcgcat aattttgacg ggacatacca
    23941 aggagaagta ccgatgtatc aagctgttgc acaaagtttg aatttgccta ctgtatggct
    24001 tttgcatgag atcggtttac aaaaaggata tgataaagca gaagaattcg gcctgccttt
    24061 agcaaaatct gataagtatt atggcttagc ccttggtgga ctggaaaaag gagtatctcc
    24121 attgatcatg gcgggtgctt acagtgcatt tgccaatgat ggtcagatgt atacgccgca
    24181 tcttatcacg aaaatcgttg attcgactgg agcggtgatc gtcgataaca caaacaaaaa
    24241 accaaaacag gtcatatcaa aggaaacagc cgatgaaatg accagcatgc ttcttggtac
    24301 attttcaaat ggaacagcgg ctgctgcgaa tcctgcaggt tatacgatag cagggaaaac
    24361 aggaaccaca gaaactaatt tcgatgccac aaaagcaaat gaccaatgga tgatcggtta
    24421 cacgccagac gtagtgattt cgacatggat gggttacgaa gaatccagca agctgcacta
    24481 tttggaaggg acaagtggaa atgttgtcgg gaaagtcttc aaatcagcgg cagaaggcat
    24541 ccttccgtat acttcaaaaa caggatttag tgtagcagat gcctatgcca caggaggaca
    24601 agtggtagct gcagatcaag ttggaaacac aggaaattct aatggagagt ctggaaattg
    24661 gcaagataac ttgaatcaat atggtgaaca agcaaaagaa gggctgaaaa acttcggcga
    24721 tatggtgaaa gaaggcgttc agggaattgg tgaagcggct aaagacctct ggcggaaata
    24781 tcaaggagag tagccccttt gaaaacgaat aaccccatgt tacaatagag agtaactact
    24841 aaaagaaaag agggcataac atgtcaaaca tctacgatag cgcgaatcaa atcgaacgtg
    24901 agatccgtga attaccagaa ttcaaagcgt tgaaagaagc gtacgagaaa gtacaagcaa
    24961 acgaagaagc acacaaactg ttcaaagact tccaagcgat gcaaatcgaa ttacaagaaa
    25021 aacaaatgag tggacaagag ttcagcgacg aagatgcaat gaaagcacaa gaaatggctg
    25081 tgaaaatcca atcagaagaa gtaatcaatg acttgatgca aaaagagcaa ggcttcagta
    25141 caatcatcaa tgacttgaac cgtatcatca tgacaccagt tcgcgacctt tacagcgaat
    25201 aaaactattt tatgaaacaa cagagggtgt gaaagagacg ttcggccttg agcgatgaca
    25261 aaattgcttc ttattgccga taggctgtct cttgaacacc atttaccaag aggtcgtgag
    25321 cctaccgttt aactctgagt tacaaggaac aatttcaaaa aacagcttct catgtttgat
    25381 gactattgtg acttgtgacc gaggagttgg caggagaaca ccgtttattc agaaatagga
    25441 gctacgacaa aagtcttgtc atagctccta ttttttgtca ttcatttttc aagcggtaga
    25501 aatagccttt ttgagctaac agtttttcgt aagtacctat ttcaacgatt tttccttcat
    25561 cgatcacaac gattttatct gcctctttga tcgttgaaag ccgatgagcc acaataaaag
    25621 tagtgggtgt ttctgtcagg taattcaggg cttgctggat ttttttctct gactggttat
    25681 ctaaagctga ggttgcttca tctagcaaaa tgatttttgg ctgacgtatc aacgctcgtg
    25741 caatggagat acgttgcttt tggccaccag acagcttgtt gccatgttcg cctactaagg
    25801 tatccagacc atcaggaagc tggtcaatca gtgaagaaag ttgcgcagct tcgatgactt
    25861 catctaaacg ttcttttgat acgtttttca agccataagt gatgttctct ttgatcgaag
    25921 cggagaacaa caaagtggtt tgaggaacaa cggctaaata atttcgcaca cttcgcatat
    25981 ccagttcatc caaaggctga tcatctagaa aaatttttcc tgaagtcggc tggataaatc
    26041 caatcaataa gttaaggagt gtagattttc cagagccaga tggcccaaca aaagcaattg
    26101 tttctccagc tttcacctct agagaaaaat gatcgataat cggtttgagt gagtccggat
    26161 aaagaaaaga aacatcctca aaacgaaaat ttccatccaa atgttggatt tttttcttac
    26221 cgtgataagt ttctacatcg ccagcaatca acagttcgcc aatagaagtg atagattcca
    26281 tgccttttga aatcgtagga atcagcgtga tcattccaga aacggaattg acgatcgtcg
    26341 tgaaatacgt ctgatacatc acgacatcgc cgggttggat gcgcccttgt aaagctaata
    26401 tcccagtgaa aatcaaacaa atcagctgaa atatctgaaa actagcccag ctgactgatc
    26461 cgaaaacaga ttgcaggata tctaagtgga atcctttttc atagatttga gtaaaatgct
    26521 tatttaagcg agttgtttcg tgtttttcta acccatgagc tcgagcaatc ggtgctaatt
    26581 cgatcacttc gatcactttt gcagaagtct cttccatttc ttgcctgaag tctgagttgg
    26641 actgtctgat ccttttacgg aaaaagagag taacgaatgc ggcgagagga acagtcaata
    26701 agaaaaacat gaaaacaaca ggacttttat aaagcgtgat acctaaagct acgaataaat
    26761 tgacagcgat atttaatccg ctgacaaata cttgagagga caacgtttgg atagcttcta
    26821 catcacggat gatctttgac tggattcgtc cagattgcaa ttctttttga taaggaatag
    26881 atagttcttg gattttcttg ataagggtcg ctcttagtcc agcttctact tgacggatcg
    26941 aagtgctatg gtattttaca tgaaaataat tcgtcaatat attttgacca atcagacaag
    27001 ccatcaaaaa agcgttgaaa taaatggcct gcaactgaga agaatctttc gatgaagctg
    27061 cattgattac attggcaata gcgatcggca ttaaccaaga tggaagatgt ttgataataa
    27121 aaaagagtcc tgacatggca aaacgccaat aatttccctg ataaagatgc agcaatgtct
    27181 gaaaagcatt tgcatgatat ttttgataac ttttctgtat tcgttcctcc ataatcttct
    27241 ccttaacaat cttggtaaat aaactgcaag tgttctattg cttcaggaac ataaatctca
    27301 ggagtagctt caagagtggc gtacattaga ggacgctcat atttgatata atgcagtacc
    27361 gggcggaaat ctaaacagcc cttgccaaca ggtaccatgc ggatctttcc attttccatg
    27421 atatagtctt tgagatgaag cgctgtaata taaccatgta aattgtccaa ggcacctcgg
    27481 atcacttttt cctgatcagc atgattttct ttatgcatca aattcgcaca atctaaaatg
    27541 atttttaaat ttggtgaagc tacttcatcg attaaacgtt tagctaactg atagttatag
    27601 attggatgat tgatccctgc ttcaacagca acagttacgc caaaattttc tgcatgagcg
    27661 actaattcaa tgatagaatt tctggcgatc tgataagctt cttcagtaaa attttctttt
    27721 gtgtaaccga cagagacact accggtttcc gtagcaatca tcttggcttg ataggcagag
    27781 cacagagcaa tttgctgttt gaaagttgcc aatgcttgtg cacgaacttc ttgatttttg
    27841 ctggataggt tgatatagca tcctaaaatg gaaagttcga tattgttttt ttggaagtat
    27901 tcaccaaaat aggcagcact cccaagtgtc atgtcagtta atttaagttg ttcaggaaat
    27961 gctttttgtg gtgcaaattg gatatgggac aagtgaagct gtgatacttt ttgaacgatt
    28021 tcttcacgat ttcgaacatc taaatcgtgg gcacggatgc ctaaatttaa tggaaacatc
    28081 tcaaactcct ttttgtaaat aattagcaag aggcagacgg gattctttta tcaattcaac
    28141 aattattcgg gcaactttat cagcgccttc tggactaaag tgggtattgt cttttagtcc
    28201 ttctgggtaa tttttacaag tatcaggtat aagatgcagg tagaattttt ttgtctcttc
    28261 ttttgagaag gtctggaaca attcttgtga tcttgagaac acatctaaaa gaggaatatg
    28321 gtgtttctca gcaaatgcac gcatcgcttt tggatagtct ccaagtatat ctggattcaa
    28381 tgttccgttt tctaagtaat ctcgtcgcgt cacagatgtc agtaagacca tttggacgtt
    28441 cgcttttttt gcgcattcaa aaaatatctg cagatttttt aaatagctac cgaagggaag
    28501 cgtacctctt tcttcttgga ttttctggtc gttatgtcca aattgtacaa ataagaaatc
    28561 attcggctga aactgtgaag ctagacgggc taaccttcct tcctggataa atgatttggt
    28621 gctgcgtcca ttctttgctt ggttattgat ctggatctcg ggtgaaaaat aagcagagat
    28681 tttttctccc caacctgtct cgggacgctt gttttcatct ttttctgccg cagtagaatc
    28741 accggcaata tggatagtag gcatgttatc tcttctttca taaaggttta taggcaatga
    28801 agcagaacag caagagaaga agacggagca aatttggtcc gtcttcttct ctaaaacgtg
    28861 gataaacgga ttccgttatt tcactatcct gtttttgatt cgttactgtt actattaatc
    28921 aattaggcaa aaaagccaaa gtaattttta gcatttgtat aactaatcgc ttgaactaga
    28981 cttcctaaaa gttgttcatc ttcaggtgct tctcctcgca tgaccatttc gcctaaaaat
    29041 tcacaaagaa cacgacggaa atattcatgt ctagtgtagg acaggaaact tcttgaatct
    29101 gtcagcatgc cgacaaaatt ccccaaagca ctaccatcag caaattgtgt caattgatcg
    29161 cgcataccag ctcgagtatc gttgtaccac catccagaac ctaactgcag ttttccattc
    29221 tgttcttttt ggaaacagcc catcaaagct aaaatcgcag gatagtcatt cggattcaat
    29281 gaataaagga tcgtctttgg caactgatcc gtttcttctg cacggttcaa taatttttgc
    29341 agaggaatag tcaaagaaag atcattcatt ccatcatagc cggtatcggg ccctaatttt
    29401 tccaacattt gtgtattaca gttacgataa gcatggatgt gcagctgcat cgtccaatta
    29461 tgagaatgat agaagtgggt caaatgtatc agtgtttctg tacgataagc atcgatttca
    29521 tctgaagata atagtttgtt agctcgtgct ttttgaaaaa tctcttctaa tactgtttca
    29581 tccgcttctt tatagcgtaa gatgtctaaa gcgtggtcgg aaacacgaca tccatgttga
    29641 tggaagtatt ctatccgctg ccctaagact tctatcagtt cttgataggt ggtgatcgtt
    29701 tggtcagctg cttcttccag tagtgtgacc catgcattaa atccttcttt ttcaatattg
    29761 agtgctttat ctggacggaa tgaaggtaga accttcaaat ctggttcttc atgagcaagc
    29821 aactgatgat agtgcaagtc gtctgcggga tcatctgttg tacaaatcac ttctacattc
    29881 gatttttttg cgatttcccg acggcgaaaa tcaggagctg ccaaaatttc atttgcttgt
    29941 gtccaaattt tctctgcatt ttcttcattt atcaacaagt caataccgaa gaaacgcttc
    30001 aattcaagat gtgaccaact gtaaagcgga tttccgataa tttttggtac ggtttgacac
    30061 caagctaaaa atttttcaaa atcagaagca tttcctgtga ttttttcttc aggcacgccg
    30121 caagctcgca tcaagcgcca tttgtaatga tcgcctccta accaagcttc tgtcagattg
    30181 ctgaaattgt tgttttcgta aatttctttt ggatctaagt gacagtgata atcaataatg
    30241 ggcatgtttt ttgcgtagga atggtaaagc tttttcgccc aatcgtcttt taataaaaaa
    30301 tcatcagata aaaacataaa tcttccttct ttctttttat actgttttat gaaaatcaaa
    30361 gtgttactcc gtttttaaaa atggcaattt ctcgaacgtc attttgttca tttttcgttt
    30421 cttctccact agctacagcg atgatttttt gaacaaacga ttctaagatt acttccattg
    30481 gttgttctaa taagacgcct gcattaaaat ccatccaatg acctttgcgt tcaaaaagag
    30541 ttgtattcgt agataccttg accgttggga catatgagcc aaacggagtc cctcttcctg
    30601 tggtaaacaa gaccaactgg caatcggatg aagcaagagc agaggcagct acaagatcat
    30661 tcccgggagc ttgcaataaa ctaagccctg gttttctgat tttttcgcca tattgtagca
    30721 catcaacgac aggagagctt cctgattttt gcgtgcagcc taaagactta tcttctaatg
    30781 tagtgatccc acctgcttta ttaccaggag atgggttttc gtaaactggt tccccgtaag
    30841 acaagaaata ctgtttgaag tcattgatca agtcaacgat tgagtcaaaa acttcttcat
    30901 tttccgctcg tgccatcaat acttgttctg cgccaaacat ttctggcact tctgttaaga
    30961 tcgtgctgcc tccttgagca atcaagtagt cagaaaatgc accaagtaaa ggattagcag
    31021 ttattcccga tagaccatca gaaccgccgc atttcaaacc gacattcaac ttagagagcg
    31081 ggactgatat gcgctggtca ttttccgccg ctgttaaaag ctcttctaat agagccacac
    31141 cttgttcgat ctcatcgtaa acatcttgag ccactagaaa tttcactcgt tcttcatcat
    31201 attcacctaa aatttttttg aattcaggaa ctgtattgtt ctcacaacct aatccaaata
    31261 ctaaaactcc tccggcattg ggatgattta ctgcgtccgc taaaatttct cgagtatttt
    31321 gatgatcttt tccaagctgc gaacagccat aaggatgctt taaaatcgta atatggtcaa
    31381 actgtcccag atctggatgt ttttccttga actgtttgac gatcagttca gcaatgccat
    31441 tcacacaccc aacggtaggt actaaaaaca aatcattacg aatccctact tttccatttt
    31501 ttcgcaagta accttgaaat gttcggttct caaaaaggta atgacttgga tggacatctt
    31561 tttcatatcg ataatccaat tcaccagaaa gattggtttt tacattatga gtgtgcagcc
    31621 attgaccggc agttacgtct gtcgtcacat gaccgattgg atagccatat ttgatcacgt
    31681 tgtctccagc tttcaaatca cccaatgcaa tcttatgacc ttgcgggata tcttcaagag
    31741 tggtgatcgt ttgctgatca atcgtcagtt gtgtttgttt tggaataggg gttaatgcga
    31801 cgaccacact gtctcgtcga tttaatttca ttgttggttg cagggtttca agcatggacc
    31861 atcgttcctt tcatttcttg taatactgac cggacacctt tttgatcgat ctttgcagct
    31921 atttcttgaa ctgtatctgt cacattcggt atttgagaca aatcttctcc ccaaagcgca
    31981 gcgttttgca ataatcgagg aatagctgtt ccattatcag accaagcatc agtaaattcg
    32041 cttatcgtct tttcatcatc atgtggcttt acttgatcgc ctcgatacat aagaagtagc
    32101 gcagctagtg aaacagtgat taacggtggt acctgatttt gttcttcgat atacttcttg
    32161 aacactggaa gcagacgggt gctgaacttt gaaacactat ttaatgaaat cgcttctaat
    32221 ttgtgatggg caaaaggatt caagaaacgt tctttgattt ggtcagcata aatggctaat
    32281 tcatctttag gtaaagaaag cataggaatc aattctagat tgaataactg atcaacatat
    32341 gcggagaata aaggatcttt cattacttct tctacagttt ccaattccgc caacaaagca
    32401 agagggacca tcgctgtatg cggtccatta agcaaatgca ccttacgttc acgataagga
    32461 gtcatatcat ctgtgatgat gacattcaag ccagcctgtt tgaatggtag ttgattctcc
    32521 aattctttag gcccttcgat cacccaaagc atgaatggtt ctgctttgac catcaattga
    32581 tcttcatagt tatgccgttg attgaaaaca cctgcatctt cgcgaggata acctgggacg
    32641 atgcgatcaa ctaaactaca acagaaaaca ttttcttttt ctaaccactc aacaaaagca
    32701 ggttctaaat cccatttttc tgcgtagcgt aaaatgattt cttttagacg ttcgccgttt
    32761 ctgtcaatca gttcgcaagg aatgatggta aagccagctt tgtttaattt gaaacgtcgg
    32821 tataaaaagg ctgtcagttt gcccgggaag ctctgtgggg gagtatctgt taaattatca
    32881 gtctccacga attggattcc tgcctctgtt gtattggaga cgatataggc caagtcgtca
    32941 ttttctgcta gagatagata agcatcccat tcatcataag gattgatcat ttgttctact
    33001 acggtgataa tctcggaagt atcaacgatt tcgccattgc tgagtccttg taaaatgacc
    33061 gtatataaat tatcttgctg gttcatcata tttccaagac cttgttctaa aggttgaatg
    33121 attgcaacat tacctttaaa caattgttgg ttattcagct gctgaatctg ccaatcaata
    33181 aatccacgca taaaattgcc ttcaccaaac tgaagaactt ttacaggtgc ttcgtttttt
    33241 ttcactaatt cttttgtcag ttttttcata taaacttcct ttctgtgtta tgcacacgtt
    33301 aacattttta tataaaatta cttgtagttt acaagtaatt gatcgactca cgaaggatca
    33361 acaaggtgga gagctcaatt ttagattgtt cgatcgtcct gccttcgatc aaatctagta
    33421 aaagctttgt tccttcttga cacatttctt tcaaaggctt acgtacggtg gtaagcggcg
    33481 gattgagata ggagacgact ggagaatcat cgaacccgat cagagaaatg ttctggggaa
    33541 cacggaggcc agctaaatgt acagctctca atgcaccaat cgctatgtcg tcgttgccgc
    33601 aaaaaaccag agtaggcagg tcagaaagtg ataataggta ttccatgttt tggaggccgc
    33661 tttctaagct gtaatctcct gttaaaaaat aggctggatt gacagggatg ctcgcttttt
    33721 ttagactttt caatacccct ttttcccgtt cttttgtcga acgaaaattt ttctttccgc
    33781 caatataagc gatcttcgta tgtccgcatc caataccgta atctactgcc tgcataacac
    33841 cggccgcatc atcggcagtg acgttgataa ccgctggatc attgatgtga cgattgacaa
    33901 caacgaaagg aaattctttt tctttgagat agtcgatgaa aggctgatca tcatcacttt
    33961 gactcataac gatcagtcca tcgtagcgtt gcaggttgat ttctgttaaa tcaacaacat
    34021 cgatactttc aacagataaa ctgtaatttg tgtctaatac tgaatggatg cctgcaatgg
    34081 aatctgctag gaaatttgat gaagttcctt tatgcaaact tgagaaaaat agtccgatta
    34141 gatatttttt ttgattcact aaaccttttg cactatagtt tggcgaataa ttcatttcct
    34201 tagctagttg tcgtattttt tgttttgttt cattttttat taaactgctg ttattcaaag
    34261 cacgagaaac tgtcgtatga gaaacgccag ctgctttagc gatatctttg atcgttacca
    34321 ttccatcatt ttccttactt tttcactttt tgttaacgca ttcatcatat tacgataact
    34381 acgataagtc aatagatctt tgatatgaaa agattgcaca cgttaaaaat tacttggatt
    34441 tttattttta attatgctat tcttgaaagc ggggaatgct catttaatta gatgagtatc
    34501 aattttacag aaaaatgaaa gccttttatt ttaaaaggag gagaggaaga aaatgaagaa
    34561 aagtacagta ttttataaaa tatttttacc gatgttttta ttaggagccg tacttgtcat
    34621 aggatttagt ttattcattt accagaatac ctatgaatcg atcgaatcga gttatttaac
    34681 agacaaaaag aatttgctca ggcaagttaa aactaacgtt gaatggaaaa ttagaacgat
    34741 tgaatattcg ttttctacgt atggttcgac caaaaatttc tcggacatat tcaagcatcc
    34801 gctgacatat acagattact ccacttattc tgaaatcagg aaagaactaa attttataga
    34861 aacgattgtt atggatgata ataattatga tttagtcagt ttggctggta aatggggagt
    34921 aatcaatgga tcgttgagtc aactgaccga agaggaagtt gaaaagtatc aacagaagta
    34981 cataaataac aaaaataatt tattttggca aaagaaaaac aaaggaatcg aaatggtgat
    35041 ttctttgcca atgtttgaaa aagaaaaata tgcattggga attgctacga tagagaaaca
    35101 tacaatagaa caagttgttg gtgaaagtgg agaagacata ctttctattg aaaacgaagt
    35161 tggcaacctt tttactactc agacagtaaa aaataaagag caaccaactg tattaacgga
    35221 cgtggatcta gattacaatc agctgaaagt gataagagaa aaagataaaa cgtatatagt
    35281 actgaaatca gattataata attggattta cagattagaa gttgactcta gtgcaattgg
    35341 cgcaatgatc cgcaatctga gaatcgggct agttgcagtg tctttaacac tggtaggact
    35401 cattggtctt ctttcctact tattttcgga cagatttgcc cgtccgattt ctcaaataca
    35461 ggaacgtctg aatcttaaat caaaaggatt cagtgggaaa gaactagatt tggtcgctca
    35521 atcagtcagt cggatcatag gagaaaaaga agcgttaagt gcacacttag ttacccaaaa
    35581 gccacagctg gaaacgctat ttgtacttag tttatttaga aatcgagtag aaaggcgaga
    35641 actagatcag cggttgcagc aatttggtta tagttctcaa aatgactgct attatacagc
    35701 tttggttcaa atcgatctgt tagaagatag tcacggtggg gagcgtgatt tgctactttt
    35761 agcgatcaac aacatgatca cggaaattgt gccaaaggaa aatcgaatgc tgccgatcgt
    35821 tttgaatgaa gaaatgcaag ccactattta tcgaatggat aaagatgatg cagaagcaag
    35881 caaaaaagtc atggagtatt gccgactcat tcaaaaacgt gtaaaagaat acttgaattt
    35941 aactatcagt ataggcatca gtaaccggtt cgaaacgctg aatgaaagca agcaatcggt
    36001 tgatcgggca aaagaagccc tgtattatcg tgtaaatact ggtccaagtt caattatttt
    36061 ttatcaggaa atcgttcctg ctgctcatga aaaaacactt attagatatc cgatagaaga
    36121 acaaaatcga ttgtttgaag ccattcgttc tggaaatcag gaagtgaaga atttagtaca
    36181 tgaattgatt gatgcattgt ttgcacaaaa taaaaatcct ttgagtcggg aagtagtttc
    36241 ggtccgcttg atcaatgaac tcgttcaatt aggacagtta ttgggagtag attcaaaaaa
    36301 ctttgataac atgaaacaaa tttatgtaaa agcactgaac aattatcatc ccaaagaact
    36361 agaaaaactt gttttagaac aattagttct gccaatcaca gaatgctctc aagcaatcac
    36421 tgatcatgaa tttaaaaatt tgtcggagaa tattatgcat atcgtctaca cagaatatga
    36481 tcgtgatctg tctttagatg tgatcgctga taggttgcat tataacccta actatttaag
    36541 taatgtattt aaaaaggaaa caggagaaaa atttggtgat tttgttcaaa atcatcgttt
    36601 agaggtagca aaaaaatggt tgaaagagac taacctctcc gtaaaagaga ttgcagaaag
    36661 attgcaatat cgaaatccgc aaaattttat tcgtttcttt aaaaagaagg aatcgattac
    36721 gccgggagaa tatcgaaaaa aatatttgtg aatcaagagg ctgtttttct tgtggactga
    36781 ttcaagcaat aaaagaagtt agaataaccc tagtatttgt atttatggat agttaaattt
    36841 caaggctaag cacgcaaaaa gaactgtgac aaaagtcttg tcacagttct tttttacgaa
    36901 taaatggcgt tcaagagaca ggctatcgac aataaggcat aattttgtga aatatgggaa
    36961 gctatttttc aaaatcgctt cttattgctc ctgtgggtta ctcgtcgcaa tgtttgtgag
    37021 agtttttatc atcgctcaag gctgaacgtc tctttcacaa cctctgatac acggtgttcc
    37081 aggagtagat tcttcgaaaa ataagccgaa atttcacaaa aatttaagaa gcaattttcg
    37141 taaatgcctt cttatttctt gaagctgacc acttctgaca caactaccat tttgcgttca
    37201 gtacataatc accctttgac agaacctacg agtgctcctt tgacaaaata tttctgaaca
    37261 aaaggataaa caatcagcat aggcactgtt gcaataacga taacagccat tttaactgtt
    37321 tgtgctggtg gaatcacatc aacggcacta ctttctgctt gcatcccact tgatacaatg
    37381 acgatttggc gtaaaagaat ctgtatcggc catttagatg aatcgttgat atacaaaata
    37441 gcagtcatat aagtgttcca gtaagtaaca gcataaaaaa gcgagatagt agcaatagac
    37501 ggtaacgcta atggcagcat aattttgaaa aatacaccaa aatctgtgca accatccatt
    37561 tttgctgatt cttccaaact atccggcaag gcttggaaaa agtttctcat aatgatcata
    37621 ttcattgcat taacagccac aggcaggatc atggcccagt aagaattgac cagccctaga
    37681 gaacgaacaa ctaagaacgt tggaatcatc cccccgctga acaacataga aaatacaaca
    37741 agaaagttga cgaaacctcg accaaacaaa tactttctgg aaagaccgta ggccatcagt
    37801 gaagttgcac acatactgac gatcgttccg acacctgtaa caccaatcga aacagcaagt
    37861 gctctaaaaa tggtcggcgt agaaagaatg tagcgatacg cgtctaaaga aaaggtagta
    37921 ggaaaaagga taaacttttt cgcgacgact tcttgtgtag aagcaaaaga tgtagcgatg
    37981 atatttaaaa aaggaacgat acagatcaaa gctagcaaaa ttagaaacgt attgttgaaa
    38041 agtgtaaaac ttctttctcc tatagagact ttctttttca tatagatagg ctcctcctca
    38101 aaataaatta aatgtttctg tttctatatg ttcaatttat catcggtgaa agattacgta
    38161 tataatcatt tcctatgcta agtgtcagat agaaaaaaat agaaggtttg ctatgcgtag
    38221 tttatttgtg aaaaaataca ctttatcgtt ttgtatagca caaaaatcat tgctatgtaa
    38281 gcgtttttac ttacggtaaa aatgattata tacgtaattc agatagttat ctatcatgaa
    38341 gtcataagca gcaaacattc acaaaactaa ggaggggctt atggaaagtg taaagaaaca
    38401 agaaccattt caactgacgc tatcgaaaaa agaagaaaag ctcagaagac gaaaaaaaat
    38461 aattgcagga atcaaaacga ataaattttt atatgtgatg attctgccgg gagtccttta
    38521 tttcttgatt tttaggtatc ttcctatggg gggactcgtt attgcttttc aagattatca
    38581 accattttta ggaataatgg gaagtccttg ggtcggtttc aaacatttca ttcgtttgtt
    38641 tacagaaccg acattcttta cattattaag aaatacgttg atcttgttcg gattaaatat
    38701 cttcgtgttt tttccgatgc caatcatttt gtctttacta ttaaatgaag taacgaacaa
    38761 acgattgaaa aacgggattc aaacgatcat ttacatccct cacttcatgt cttgggtaat
    38821 cattgtttcg attacttatg tatttttgaa tgttgacgga ggggtattga atgaattcct
    38881 tgcaacaatg ggatttgaaa aaatcagttt tctaacatcc cctgaatgga cacgcacagt
    38941 atatatcgga caagtgatct ggaaagagtt gggctggtct acgatcatct acctttcagc
    39001 gataactgca gtcgatacac agttgtatga agctgcagaa atggatggag caggacgctt
    39061 acgcaaaaca tggcatgtta cattgccggc aattcgtcca gtaatcatta ccttgctgat
    39121 tctaaaaatc ggtcagacat tagacttagg gttcgagcat atgtacttgt tattgaattc
    39181 attgaatcga agcgttgcag aaattttcga cacctatatt tatacagctg gattgaagaa
    39241 tggacagtta agtttcagta cagcaatggg attgtttaaa ggggtcgtag gattgtttat
    39301 ggtaatttta gctaataaga ttgccaaaaa gctaggagaa gacggcgttt actaagatag
    39361 aaagagaggg aaagatatgc tgcagtcatt agataaaata aacggaaggc taaatcgtat
    39421 tttacagttg gtttatttga attttctgtg gggcggttta gtcatcgcag gtttgggagt
    39481 ttttactttc ggtcctgcat cgtatgcgat ggttgcagtg attagaaaat ggctgcgctc
    39541 aaaagaaacg tttcctttga cgaaaacgta cttcacatat tttaaagaaa actatcgtga
    39601 aaccttgctg atgagctgga tatatggcgc catcgggatt gttttacttg tggatctttc
    39661 tttcatacac aattggtatc ttaggatcgc tttgtatatt gctgcgttca tatatgtgct
    39721 ctcagcactc tatattttcc caatcatggc tcattatgat tggaaaggat attttttcaa
    39781 aatgaaaatg gcatttttat tcggattctc acatcttcat tactcattag tgttgatatt
    39841 aagtatggta gggatttatc tgatgatcat ccaaacaatg ccaggtgttt taacctttat
    39901 cggtggcagt ctcttctttt ccgcagtcac gtggacagca aattctatat tttgccattt
    39961 ggaatggaag aactcatata cagaaaaaac agaagaaaac aaaaatatta ttaaaacagt
    40021 gaaggagaaa atttatgaaa aaagcaacgc tcgtaaaatt aggtcttagt tttgcaggaa
    40081 ttctagcact tgccgcatgc ggcagcagtt caagtaacag ttcttcagag acagaagatg
    40141 gaaaagctaa aatcacttgg ttaaatattt tgcatcatgc ttcaccgcct acagacacga
    40201 ttgtgaactt gatcgaagaa aaaaccgata cggaactgac attcaactgg attcctgatg
    40261 cttcaaaaga agaaagatta acaactgcat tggcttctga tgaactagga gatatcgtta
    40321 cacttcaaat tgcgatgttg aaaaactctt ctgtccgcaa tgcgttaaaa tcaggcgtat
    40381 tctgggatgt atcagaatat ttaaaagact ataaaaattt aagtcaaatt tctgaagata
    40441 gaatcgaagc tgcgagtatc gacggtgcct tgtacggcgt accgatacaa aaagactacg
    40501 ctcgtgctgg cttagtcatt cgaaaagact ggttggataa tctaggacta gatgttccaa
    40561 ctaccatgga tgagctttat gaagtagcta aacaatttac agaaaacgat cctgatggaa
    40621 atggtgtgga cgacacagtt ggttttggcg atcgtgcgcc tagtgatatt cgttatacca
    40681 gctttaaact tttcacttct tattttggag caccaaatgg ctgggctgta gacgataatg
    40741 gcaaattcac tccagaattt gatacagaag agtatatgaa agctttgaat ttttcaagag
    40801 atctatttga gaatggctat ttggcacaag actttgcagt tacccaaaag actgatcagc
    40861 aagaacaatt tgcacaagga agaactggaa tctacactgg aatggtggat atcaagaatc
    40921 tgaagacgat gggtcaaggt attcaagatg atatggaatt agtgcctgta aacaagatct
    40981 cagatggtga aggcggcggt tatcatgttt ggtcagaagg aaatggtatt ggcggcttgc
    41041 tagcatttcc caaatctcaa gtaaaagacg aagcacaatt gaagaaatta cttcaatttg
    41101 ttgatgatct tttagaagaa gatgtgtata aattgatgac tggcggtatc gaaggaacgc
    41161 attatgaatt gaatgatgat ggttctatcg aatttatcga tatggatctt tggcaacaag
    41221 aggtgcaacc gttatcaagc tctcgtccta gtgaagtgac gttctctttc aaagatacag
    41281 accctgaaaa agaattctct aatcaattga tcaaagaaaa tgaagaattt gctgtaatgg
    41341 atccttctgt gccattggat tcaccgacga acaatgaagt aggatcagaa attgaaaaaa
    41401 tcgtcattga tgctacggtg caatacatca tgggacagct tgacgaagat ggattcaaaa
    41461 aagctgtaga agactggaaa gcacaaggag gcgatcgaat cacacaagag tacgaggaag
    41521 catacaaagc agcggcacag taatatagac gattgggaca aatacttctt ggtatttgtc
    41581 ccaaatccta ttttaatttt taaaggagag caaataatgg aaaactggtc aaagaaatta
    41641 gcaaaaagta tcatggaaag aacacctcgc ttatatgaag aaaagtggta taaaggaaaa
    41701 tggtcttatg actatggcgt cgtacttaaa gggttccaat tactttggga acgaacccaa
    41761 gaaaaaattt attttgattt cataaaagac aatatcgact atttcgtgca agaagatgga
    41821 acgatccgtg gctacagcgt tgaagaatac aatatcgacc atgtaaatac aggaaagctt
    41881 ttctttttat tgtacaaaga aacaggcgaa gaaaaatata aaaaagcagc agaactcctt
    41941 tcccagcagt tggcaaacca tccacgcaca tccgaaggag ctttttggca taaagaaatt
    42001 tatccttatc aaatttggtt ggatggctta tatatgggtt ctccttttta tgctgaattt
    42061 atccagaatt ttagtgaaga aaaagattac caagatgttt tgagacagtt tgaaatcagt
    42121 tataaacatc tattcgatcc aaaaacaaat ttgctgattc atgcatggga tgaaaagaag
    42181 gtccaaccat gggctgatcc aaaaacaggt ctatcccatc atttttggag ccgatcgatt
    42241 ggctggtatt tgatggctgc agcagatacc tatgaattac ttcatgaaga aacagattgt
    42301 tctttgctga aagaaattct agaaaagaca ctggctgcat tacttccata tcaagaagaa
    42361 aacagcggga catggtatca agtaacaaca gaaacaaaac ggaaaggaaa ttatctggaa
    42421 gcttccggca gtagtatgtt tgtttacgca atggctaaag gaatacgttt gggactgctg
    42481 aacaaagaag aatggcttcc acaagtgaag aaatcacatc aaggattact tgatgaattt
    42541 gttctggaaa caaaagaagg ctggctgaac ttgaataaaa actgtcaagt agcagggtta
    42601 ggcggagcag atcagcgaga tggttcatat gcttactaca tcagtgaacc aattatttgt
    42661 aatgatcaaa aaggcgttgg tgcattcttg caagcattga ttgaagtgga ggcattataa
    42721 atatgtatga tattttgaca tttggcgcat caattgatga attgaatact gaagcaatac
    42781 aacaagccat tgatgctgca gcaagtgacg gaggcgggac cgtagttgtt ccagcaggtg
    42841 aatttctaac aggagcttta tttttaaaaa gcaatgtcga acttcattta agcgcaggag
    42901 cggttctgaa attctctgac gatccaaaag attatcctgt tgttcattca cgttgggaag
    42961 gagtccatcg aaaagtttat gcttcctgta tctatgctca aaatgtagag aacatctctg
    43021 tcactggttt cggtacatta gatggaaatg gaaaaaaatg gtggcatact tttagaaatg
    43081 aaccagataa tctcgcttat cctcgtccta aattgatgag tttccataac tgtcatcgaa
    43141 ttactgtgaa agatattaaa ttgatccagt caccaagttg gacgatcaac ccgattcttt
    43201 gcagtaatgc aacgtttgat aacttgacga tcttgaaccc agcggattca ccaaatacag
    43261 acggaattga tccagaatca tgcaaaaatg tgcgtattag taattgccat attgacgtgg
    43321 gagatgactg tattgcaatc aaggcaggga ctgaagatac gtacgaaagg atcgcttgcg
    43381 aaaatatcac gatcacaaat tgcacgatgg tccatggaca tggcggtgtc gtattaggaa
    43441 gtgaaatgag tggtagtatt cgtaatatta ccatttcaaa ttgtatcttc caagaaactg
    43501 atcgaggaat acgattgaaa tctagacgag gtcgaggcgg gatcgttgaa gatattcgag
    43561 tatccaatat agtcatggat aatgtgatgt gtccatttat actgaatctt tattatttct
    43621 gtggtccgcg agggaaagaa ccgtatgtat gggaaaaaaa ggcttatccg atagatgaac
    43681 ggacaccagc attcagaagg atccattttt cgaatatcac ggcaaggaat gtccatgctt
    43741 ctgcaggttt tatttatgga ttagcggaac aattcataca agaaatcaca tttgacaata
    43801 tcgatgtctc gatggcccaa gatgcagttc ccggtgttcc tgctatgatg acaggaatag
    43861 aggaaatgag cagacaagga ttttatattg gctttgcggg taaggtttcc tttaaccaga
    43921 tgtcgattga aaatcacgag ggaccagcat ttctattaga aaatactaaa gaaatcagta
    43981 ttgagaaatt ccaatcaaat caatcagaaa atatggatga actggttgtt cgtaaaaact
    44041 ttgcttatgc agttgaatga ttttttaggt gctccatcta gcagacatac ccctagtgga
    44101 aaacgattat accgagaaaa acaaaacggt tttatgcttg aatactatca attgtactta
    44161 aatgaattgg aaacagtacc agccctctat gcttatccag aaaaagaagg accgtttccg
    44221 ccggtccttt acctgcattc tcacggcgga gatttttcag tcgggaaaag tgaattgatc
    44281 catggtgctc cttacttagc ttctccatct tttgcagaag tactgacagg aatgggatat
    44341 gctgtttggt cgattgatgc ttggggattt gaagaacgcg gaggtatttc tgaaagcgag
    44401 ttgttcaaac aatttttatt aacaggaaaa acgttatggg gaatgcgtat ttatgatgtg
    44461 atcagcttga tcgattattt ggagacaagg gaagacacag atactcaacg gctcgcaacg
    44521 attggtcttt ctatgggagg cttattaagc tggtgggtga cagcattgga ttctcgtgtc
    44581 aaagtttgta ttgatctagc ggcacaggtg gacatcgaaa tacttttgct acatcgccgc
    44641 ctagatcatc atgggtttta ttactatgtg ccaaatctat tgacagctta tacaacgtta
    44701 gcaatccaag aaaaaatcgc tccgcgccct cgtcttagct tagttggaaa aaacgatacg
    44761 atgtgcttgg acgaaggcgt actgaagctg agaaaagggc tggacaaaaa gtatcaatca
    44821 atgggtagtc cagaaaactt ttcttctttt tctttaacag gcggtcatat ggaaacacaa
    44881 gaaatgagaa atatttggaa acaattcata agggagcatt tatgaggatg aaagacaaac
    44941 tgataattgg aaagaatgct atagataccc cgacggattt tgaaactatc caagaaggaa
    45001 tcgattattt ggcaggcctg ccggatagcc atccaaaggt cttgatagta aaagaaggaa
    45061 gatatgatga atatatagaa agcagattat ccaattttaa acttgtggga gcaggaacag
    45121 tagttatctc cggtaatcgt tttgcaaaac aggagtatct tgacggtagc cagttaggga
    45181 ctttccgaag tgctactttt ttcttagaag gatcgaatgt cgtattagaa aatcttcaca
    45241 tcgaaaatac agcaggtcca ggagaaaagg taggacaggc tgttgcttta ttcaattcag
    45301 gagatcgcgt atctttaaaa aactgtcgac tatctggtta tcaggatacc ttatgcacgg
    45361 gtccgttgcc tgatttgcaa aaagatggta ctcctttttg tacaccggct tctgccaatc
    45421 ctgagtattg tcgtcagacc tatgaatatt gctggattga aggaacggtg gatttcatat
    45481 ttggtggggc agatgccgtt tttcatcagt gtcatatcca tagcttagcc agtaaaaatc
    45541 ctggatacat cacagcagca tctacgccga aaaatcaaaa aacagggtat cgttttgaaa
    45601 gctgtacctt gactgcagaa cctgatacta gaaacgtcta tttaggaaga ccgtggcgtc
    45661 cgtatgcaaa tgtcttattt gaagcgtgta agataggtgg gcatgttcac ccaactggtt
    45721 gggataattg ggatgacaag aaaaatgaac agactgtcaa attctctgaa cgtaataaca
    45781 attatgaaac atcgatcaaa agacctgaat ggatacattt agaaaagcag ggggttcaga
    45841 aatgaaaaga aaatgggaac tattgctagg aatggtcggt ggcagtctat ctttgatttt
    45901 ctttggcggg ttagcagtta ctttaagtaa tatgtctgcg tcagagttta aaaaaagtta
    45961 tcagtcgctt gctgtagatc attcaacttt gtctttagaa aatacatttg gattattaca
    46021 ggacatgact ggtctgtttg ccgttgtgtt gtttatttca cttgcttttt tagcagtagc
    46081 attgtttttg actgctaaag gaaaatactt aacaactgcc actggtttgt attttataac
    46141 aggattcata ttgttgattg gcactcagtt tattgcgttt ccttttgcat ttttttattt
    46201 cgcagctggg gcattcagtt tatatcgagt aagaatgaga aaaggagcct gaatcatgca
    46261 gactatcaaa gtgaaaaatc ctattttaag aggattcaat ccagatccta atatattaag
    46321 agtgaaagag cggtattaca ttattgtctc ctcttttgaa tggcttccag gaatccgagt
    46381 atatgagtcg aaaaatttag tcaactggtc acatacaacg gatattttga ccactcaagt
    46441 atctttgcaa ggaaatccta caaatggaag tatatgggcg ccacaaatca gttatgctga
    46501 tggattgttt tatcttgttt acacagatgt caaaagtgca ggccgtccgt ttaaagatgt
    46561 ccacaattat ttgatcactg catctgagat cacaggtcct tggtccgaac caatttattt
    46621 aaatagtaac ggctttgatc cttctttgtt ccatgatctt gaaacgggaa aaaaatggct
    46681 tgtcaatgaa ctatgggatt atcgtctgga cacaccgaat aaatccagcg gtatcgtatt
    46741 acaagaatat gatgcagaga agaagaagct tgatggtccc atctataaaa tatttgcagg
    46801 tacagaatta gcgaaaacgg aggcaccaca tttgtatttt cgtaacgggt attattattt
    46861 gatgacggca gaaggcggta caggaagagg acattcagtt acagtttgcc gagcaaagaa
    46921 tattactggt ccttacgagc ttgatcctgg ttttcctatg ctgacagcta gtgacaaacc
    46981 tgcttctaca ttgcaatgta caggacatgg gagcttagta caaaccccgt caggaagatg
    47041 gtacatgaca tatctttgta ccagaccatt aaacggtgcg gctattttgg gaagagaaac
    47101 cgctattcaa gaagtgtatt ggacgtccga cgattggtta agacttaaag atagccagac
    47161 aactccgatg gaagaaataa tgattgagac aaatgaagag gtacaacaag aaaaagatca
    47221 tcagtttatg gatacatttg aaggagagct aaagaagaac tggaatgcca gacgcatttt
    47281 gccaaatgct gattggtgtg atacaaaatg tagaccaggt tttttacgtc tgatttccgg
    47341 tgaatctctt caatctacct tcgaacatca tttgttagct attcggcaaa cggattttac
    47401 ttttgatgcg gagacagcat ttgaatacat gcctaataat tttaatcaga tggctggact
    47461 ggtactgtac ttaaatgaat ccaattatat ttattgttat gttacttgga atgaggacaa
    47521 gggaaaatgc ctacgtatga tagaatcaga aaacggagta gcacaaatag aagattggac
    47581 gattccactc acagaaaaga agactttttt gaaagtcact gtaaagaaag agacagcaca
    47641 gtttcatttg aaagacgtat caactgaaga atggaagaaa gtaggtccgc aaaaaaacat
    47701 gtgtatactc tcaggagggt ttactggaaa ttttatcggg atagcagtgc atgatctaaa
    47761 taaaaaaaga ggaagttatg ctgattttga gtttttcaag tatgatggaa aagatcatct
    47821 gtaatttaat tctttaataa atgaggttca ctaacttatt ttcactagtt agtgaatttt
    47881 tttgtttgta tatattgtta tgtaaaaaaa gttatcaatc ttatgcatca atgtttttag
    47941 attatttttt gttttttatc tgtcaagata atgcaataaa aagccaacat tgtgaatata
    48001 aaaacaagaa aaaaagagtt ataattttga aaacgtttac tagaagaggt aggaggaatt
    48061 caaatgcttt cacaaaatgc tgttacagca aatacaataa aaaaagaaaa aaaggaattt
    48121 gggatttccg ataagatagg ctacatgttc ggtgatctag gtaactgttt tattttaggt
    48181 ttagtcaata gtttcttgat gatttattat acgaatgttc ttggcgtttc aggggcaatc
    48241 gtaggtacgt tattcttgat ttcgagaatt ttggatgcgt ttgctgatgt gatggttgga
    48301 agattatgtg atgtctcaga gttaacagaa actggccgat ttattccttg gatcagaaaa
    48361 atgaagtatc cattttgctt agtgactgtc attttgtttt tgccattcgt ccaacatctt
    48421 ccaatgacgg tgaagattgc ttatattttt gtttcataca ttgtttatgg gatttttctc
    48481 tcaacaatca atatcccgta tggagcaatg gcagcagcaa ttagctcaaa tcctaatgac
    48541 cgcacctcgt tgtccacgtt ccgaagcatt ggttctgcga ttggcggatc aactacagga
    48601 ttcttcattc cgattttaat gtatacccat aacaagagtg gacaacaagt cgtttcaggg
    48661 aatcatttct tttggatttc aatcggatgt gctgcaatag catttgtcgc atatatgtta
    48721 acttgtaaat tgactactga aagagtaaga gttgtcaaaa acgaaaaagt atctgcttct
    48781 cagttggtaa aaggtttgtt agctaatcga gcactgatta ttttagtcat tgttgacatt
    48841 ttcattgtga tcaatcagat tttagctggg acgaatatga cttatttatt caatgattac
    48901 ttccataata aacaagcaat gtctgttgct cttttattta cttacggaac agtagtagtt
    48961 ttagcaccat ttgctacaaa gctgacaaaa ttatttggta aaaaggaagc aagcgtattt
    49021 gcgttacttg cttcttcatg tatgtacttg ctgatgtatt tccttcatat aacaaatgca
    49081 tgggtatatc tgattctttt atttatcgct actttaggat ctggtttatt caatttgatg
    49141 gtctgggcat tcattactga cgtgattgat tatcatcaat ataagacagg cttaagagaa
    49201 gatggaacag tatatggagt aaattctttt gcgagaaaag taggacaagc atgtgcagga
    49261 gcggtaggcg gatttatgct ggcactcatt ggttaccaat cgtctacaac aggtggagcc
    49321 atccaatcag ttttagtaca agaaaggatt tatacgatgg caaacttgtt accagcattc
    49381 tgcttatttg tatccgcaat cattttgcta gtaggttacc cactgaatcg ttcaaaaact
    49441 gtatttattg gtgaagaatt gaaaaaaatc aatgaaagat agggagaaac gtattgcgga
    49501 caaaaaaagg gattatcaat gctttgaact ttaaaacaaa cgacactcaa caagatgata
    49561 caataatact gcaaaaagca atcgatcaag gtgcgaaaga acacttacct gtatttattc
    49621 caaaaggcat ttatttagtc ggagcccttt ttttaaaaga taagagtcat cttatctttg
    49681 aagaaggtgc agtcctcaag gggagaacag atatcgaagc atttccagaa atcgatacac
    49741 gagtagccgg cgtagaaatg aaatggccag cagcgatttt gaatgttctc tcggcgaaag
    49801 atattcttat agaaggaaaa ggaataatcg acggtcaagg agaccattgg tgggagctgt
    49861 attggggaaa agatcaaaaa agcgggacaa gagctgaata cgatcaaaag ggacttcgtt
    49921 ggattgcgga ttatgctatt aaacgtccac gcgcttgttt actgtatcat gcagaacatg
    49981 ttgttgttcg tgatttgatt tttcagaaat caggtttttg gaacttgcaa atcacttatt
    50041 ctaacgatgt attagtagaa aaagtaatca tccgcaacaa tgatggacca agtacagatg
    50101 ggattgatat tgattcttca acaaatgtgc gtgtctatga atgtgatttg gcctgtggtg
    50161 atgattgtat tgctattaag tctggcagag atggcaatgg tgcaagagtc aatcgaaaat
    50221 catcaagaat cgaggttgct agatgtaaaa tccgttcagg atacggtgta actattggta
    50281 gcgaagttag tgctggagtt agtgacgtat atattcacga tatcgatttt tttcagtcag
    50341 actgtggtat tcgaatgaaa tcttcaaaag aaagaggggg agtgatcgaa aatatcaggg
    50401 tagaaaatct gaatatgatt gatgtacaat ttcctttttc ttggataatg gactggcata
    50461 atgaatacaa tagaaaaaat agcaatgacc ttgctcaaat gccagaaagt tggcaagcag
    50521 tggctgaaga aatacctgaa tcaaagcaaa tgacgaaagt caaagacata cacatcaaaa
    50581 acgtacaggc atgcctttct ccaggttact cacttccttc ccgagctttt gatttagtag
    50641 catttcctga aaagcctata gaagatgtct gcttttctca ttgccaaata actgcaaaag
    50701 aattcgggcg aatcgaagca gtacaaaact tatgtttcaa aagctgtgat ttatctatag
    50761 aaactggcaa cacagctgca aacaatactt ttgacaatcg ttgaaattat aataaggtca
    50821 agcttaaata atattttagc ttgaccttta ttttttttaa tgatatatta aacaacgttg
    50881 tcgcgcttca ttgaaacatt ttatgaaaat tccaaaaaag agttgacaca tgtttttaga
    50941 cgtgataaga taactaagtc gttaaaaaga accacttgcg aagcttgatt ctatcgaaaa
    51001 aaacttcaaa aaagttcttg acaaataaca aacgataagt tatgataaat gagttgctga
    51061 aagatttcga aaaacgaaat cgaaaaaaac ttttaaaaaa gagttgacaa tcgtttgtct
    51121 ctctgatatg atataaaagt tgctacggca gccaaaaatg aatcgggaaa cactctcgat
    51181 gaagtagacc tttgaaaact gaacaaagta agacaaacca aatgtgtagg gcgtcttgat
    51241 tcaattcaag acaataaac
//
LOCUS       DADVXV010000011        49976 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.011, whole genome shotgun sequence.
ACCESSION   DADVXV010000011 DADVXV010000000
VERSION     DADVXV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 49976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.011"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(180..872)
                     /locus_tag="KB969_000568"
     CDS             complement(180..872)
                     /locus_tag="KB969_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6868582.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(875..1660)
                     /locus_tag="KB969_000569"
     CDS             complement(875..1660)
                     /locus_tag="KB969_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6868583.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            1897..3297
                     /gene="lacG"
                     /locus_tag="KB969_000570"
     CDS             1897..3297
                     /gene="lacG"
                     /locus_tag="KB969_000570"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBB6868584.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            3322..3639
                     /locus_tag="KB969_000571"
     CDS             3322..3639
                     /locus_tag="KB969_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6868585.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            3652..5325
                     /locus_tag="KB969_000572"
     CDS             3652..5325
                     /locus_tag="KB969_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBB6868586.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            5339..6970
                     /locus_tag="KB969_000573"
     CDS             5339..6970
                     /locus_tag="KB969_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBB6868587.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(7461..9026)
                     /gene="guaA"
                     /locus_tag="KB969_000574"
     CDS             complement(7461..9026)
                     /gene="guaA"
                     /locus_tag="KB969_000574"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6868588.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(9085..10008)
                     /locus_tag="KB969_000575"
     CDS             complement(9085..10008)
                     /locus_tag="KB969_000575"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBB6868589.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            10204..10809
                     /locus_tag="KB969_000576"
     CDS             10204..10809
                     /locus_tag="KB969_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6868590.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            11117..12133
                     /locus_tag="KB969_000577"
     CDS             11117..12133
                     /locus_tag="KB969_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6868591.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            12274..13575
                     /locus_tag="KB969_000578"
     CDS             12274..13575
                     /locus_tag="KB969_000578"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBB6868592.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            13621..14283
                     /gene="deoC"
                     /locus_tag="KB969_000579"
     CDS             13621..14283
                     /gene="deoC"
                     /locus_tag="KB969_000579"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBB6868593.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            14304..14702
                     /locus_tag="KB969_000580"
     CDS             14304..14702
                     /locus_tag="KB969_000580"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBB6868594.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            14768..15850
                     /locus_tag="KB969_000581"
     CDS             14768..15850
                     /locus_tag="KB969_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6868595.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            16062..17624
                     /locus_tag="KB969_000582"
     CDS             16062..17624
                     /locus_tag="KB969_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868596.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            17617..18750
                     /locus_tag="KB969_000583"
     CDS             17617..18750
                     /locus_tag="KB969_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868597.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            18750..19706
                     /locus_tag="KB969_000584"
     CDS             18750..19706
                     /locus_tag="KB969_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868598.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            19805..20971
                     /gene="deoB"
                     /locus_tag="KB969_000585"
     CDS             19805..20971
                     /gene="deoB"
                     /locus_tag="KB969_000585"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBB6868599.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            20995..21813
                     /locus_tag="KB969_000586"
     CDS             20995..21813
                     /locus_tag="KB969_000586"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6868600.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            21830..22537
                     /gene="deoD"
                     /locus_tag="KB969_000587"
     CDS             21830..22537
                     /gene="deoD"
                     /locus_tag="KB969_000587"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBB6868601.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(22835..23521)
                     /gene="gpmA"
                     /locus_tag="KB969_000588"
     CDS             complement(22835..23521)
                     /gene="gpmA"
                     /locus_tag="KB969_000588"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6868602.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(23693..24274)
                     /locus_tag="KB969_000589"
     CDS             complement(23693..24274)
                     /locus_tag="KB969_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6868603.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(24407..25090)
                     /gene="rpiA"
                     /locus_tag="KB969_000590"
     CDS             complement(24407..25090)
                     /gene="rpiA"
                     /locus_tag="KB969_000590"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBB6868604.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            25409..25822
                     /gene="rpsL"
                     /locus_tag="KB969_000591"
     CDS             25409..25822
                     /gene="rpsL"
                     /locus_tag="KB969_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBB6868605.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            25906..26376
                     /gene="rpsG"
                     /locus_tag="KB969_000592"
     CDS             25906..26376
                     /gene="rpsG"
                     /locus_tag="KB969_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBB6868606.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            26470..28557
                     /gene="fusA"
                     /locus_tag="KB969_000593"
     CDS             26470..28557
                     /gene="fusA"
                     /locus_tag="KB969_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBB6868607.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            28729..29916
                     /gene="tuf"
                     /locus_tag="KB969_000594"
     CDS             28729..29916
                     /gene="tuf"
                     /locus_tag="KB969_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBB6868608.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            30323..30631
                     /gene="rpsJ"
                     /locus_tag="KB969_000595"
     CDS             30323..30631
                     /gene="rpsJ"
                     /locus_tag="KB969_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBB6868609.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            30662..31291
                     /gene="rplC"
                     /locus_tag="KB969_000596"
     CDS             30662..31291
                     /gene="rplC"
                     /locus_tag="KB969_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBB6868610.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            31319..31942
                     /gene="rplD"
                     /locus_tag="KB969_000597"
     CDS             31319..31942
                     /gene="rplD"
                     /locus_tag="KB969_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBB6868611.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            31942..32232
                     /gene="rplW"
                     /locus_tag="KB969_000598"
     CDS             31942..32232
                     /gene="rplW"
                     /locus_tag="KB969_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBB6868612.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            32271..33104
                     /gene="rplB"
                     /locus_tag="KB969_000599"
     CDS             32271..33104
                     /gene="rplB"
                     /locus_tag="KB969_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBB6868613.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            33147..33425
                     /gene="rpsS"
                     /locus_tag="KB969_000600"
     CDS             33147..33425
                     /gene="rpsS"
                     /locus_tag="KB969_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBB6868614.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            33448..33795
                     /gene="rplV"
                     /locus_tag="KB969_000601"
     CDS             33448..33795
                     /gene="rplV"
                     /locus_tag="KB969_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBB6868615.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            33809..34465
                     /gene="rpsC"
                     /locus_tag="KB969_000602"
     CDS             33809..34465
                     /gene="rpsC"
                     /locus_tag="KB969_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBB6868616.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            34468..34902
                     /gene="rplP"
                     /locus_tag="KB969_000603"
     CDS             34468..34902
                     /gene="rplP"
                     /locus_tag="KB969_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBB6868617.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            34892..35080
                     /gene="rpmC"
                     /locus_tag="KB969_000604"
     CDS             34892..35080
                     /gene="rpmC"
                     /locus_tag="KB969_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBB6868618.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            35105..35371
                     /gene="rpsQ"
                     /locus_tag="KB969_000605"
     CDS             35105..35371
                     /gene="rpsQ"
                     /locus_tag="KB969_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBB6868619.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            35429..35797
                     /gene="rplN"
                     /locus_tag="KB969_000606"
     CDS             35429..35797
                     /gene="rplN"
                     /locus_tag="KB969_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBB6868620.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            35834..36142
                     /gene="rplX"
                     /locus_tag="KB969_000607"
     CDS             35834..36142
                     /gene="rplX"
                     /locus_tag="KB969_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBB6868621.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            36170..36709
                     /gene="rplE"
                     /locus_tag="KB969_000608"
     CDS             36170..36709
                     /gene="rplE"
                     /locus_tag="KB969_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBB6868622.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            36728..36913
                     /locus_tag="KB969_000609"
     CDS             36728..36913
                     /locus_tag="KB969_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBB6868623.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            36949..37347
                     /gene="rpsH"
                     /locus_tag="KB969_000610"
     CDS             36949..37347
                     /gene="rpsH"
                     /locus_tag="KB969_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBB6868624.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            37379..37915
                     /gene="rplF"
                     /locus_tag="KB969_000611"
     CDS             37379..37915
                     /gene="rplF"
                     /locus_tag="KB969_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBB6868625.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            38076..38432
                     /gene="rplR"
                     /locus_tag="KB969_000612"
     CDS             38076..38432
                     /gene="rplR"
                     /locus_tag="KB969_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBB6868626.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            38453..38953
                     /gene="rpsE"
                     /locus_tag="KB969_000613"
     CDS             38453..38953
                     /gene="rpsE"
                     /locus_tag="KB969_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBB6868627.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            38968..39147
                     /gene="rpmD"
                     /locus_tag="KB969_000614"
     CDS             38968..39147
                     /gene="rpmD"
                     /locus_tag="KB969_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBB6868628.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            39191..39631
                     /gene="rplO"
                     /locus_tag="KB969_000615"
     CDS             39191..39631
                     /gene="rplO"
                     /locus_tag="KB969_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBB6868629.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            39631..40926
                     /gene="secY"
                     /locus_tag="KB969_000616"
     CDS             39631..40926
                     /gene="secY"
                     /locus_tag="KB969_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBB6868630.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            40988..41635
                     /locus_tag="KB969_000617"
     CDS             40988..41635
                     /locus_tag="KB969_000617"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBB6868631.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            41826..42044
                     /gene="infA"
                     /locus_tag="KB969_000618"
     CDS             41826..42044
                     /gene="infA"
                     /locus_tag="KB969_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBB6868632.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            42077..42193
                     /gene="rpmJ"
                     /locus_tag="KB969_000619"
     CDS             42077..42193
                     /gene="rpmJ"
                     /locus_tag="KB969_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBB6868633.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            42211..42576
                     /gene="rpsM"
                     /locus_tag="KB969_000620"
     CDS             42211..42576
                     /gene="rpsM"
                     /locus_tag="KB969_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBB6868634.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            42604..42993
                     /gene="rpsK"
                     /locus_tag="KB969_000621"
     CDS             42604..42993
                     /gene="rpsK"
                     /locus_tag="KB969_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBB6868635.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            43073..44011
                     /locus_tag="KB969_000622"
     CDS             43073..44011
                     /locus_tag="KB969_000622"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBB6868636.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            44039..44419
                     /gene="rplQ"
                     /locus_tag="KB969_000623"
     CDS             44039..44419
                     /gene="rplQ"
                     /locus_tag="KB969_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBB6868637.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            44691..45530
                     /locus_tag="KB969_000624"
     CDS             44691..45530
                     /locus_tag="KB969_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6868638.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            45506..46375
                     /locus_tag="KB969_000625"
     CDS             45506..46375
                     /locus_tag="KB969_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6868639.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            46365..47162
                     /locus_tag="KB969_000626"
     CDS             46365..47162
                     /locus_tag="KB969_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6868640.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            47365..48111
                     /gene="truA"
                     /locus_tag="KB969_000627"
     CDS             47365..48111
                     /gene="truA"
                     /locus_tag="KB969_000627"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6868641.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            48776..49013
                     /locus_tag="KB969_000628"
                     /pseudo
     CDS             48776..49013
                     /locus_tag="KB969_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(49157..49933)
                     /locus_tag="KB969_000629"
     CDS             complement(49157..49933)
                     /locus_tag="KB969_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6868642.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
BASE COUNT        15797 a         9145 c        10885 g        14149 t
ORIGIN      
        1 atgttaatta tagatagaga tgaacgcgtc atatggttaa aagaatgaaa aagtcaaaga
       61 tacactgcta tatttcacta aggatatagc agtgtatctt tcatgtcgtt tcactggcag
      121 ttttttataa aaggaggtgt gcatttcagt tgcttttctt tggtagttag ttgaatcgtt
      181 taagaattaa cggatgtggc agacaggtgc tctgtccaaa aaccagtaaa atctttgatg
      241 gttccatctt tatttagctg tgcctgttca aatactgttt tgtttttacc gaatggatca
      301 attgcaataa ttgttccgat ccccgcacgt ttggcagcaa gtaatcctga gtaagcatct
      361 tcgataacaa gacaatcagc cggagctaag ctcagtttgt ctgccgcttt aagaaaaata
      421 tccggttgcg gtttcccagg gaaagagccg tcgtcataga caatcttgtc ccagtcaaac
      481 cagcgggcta aatcgaaaat atcaaaataa aaagcaacat tctctttgac agtagccgtg
      541 gcaatcgtta atggaatctg ttggtcagtc agctggtcaa gagtcgcttc aagccctttt
      601 gtcaactgaa gctcgttttc attttgcaag caaagcatac gataatagct ttctttttct
      661 tctgacaata cggcgatctc agaggcggtc aaatgctctg aaatgaaatg tttcaaaatc
      721 tccgtattcg tccgaccatg aatatttttt aaaatatcct cgtctgataa accatctttt
      781 gtatgatcat gtatcatatg cagccaagca gcttcatgca gatgagagtc caaaaacatt
      841 gttccgttga aatcaaatat aatccctttc atagttacgc tcctatagtg gtattttcgg
      901 ttgaatcagc aatttgcaga tcgacatatt gtgcatagtg ctcttgaacc tcccgcgaga
      961 tctggcgatc cgtaatgagc agatcgaaat catgcaaatt ataaaacaca taaaaatcat
     1021 ctcgattgaa ttttttatta tcaacgagta gatatttctt acgggaatta tttagagcga
     1081 tctgctgtgc ttctccttct tcggtactgt aagtagagat cgcttcgttg tgaacgccat
     1141 ttgaactgat aaatgctttt gtaaacttta gtcttcttaa attgtcgttg gtgatcggtc
     1201 cgacaaatgc gccggtattt ttccggaaat caccgccaat cagtagaatt tctggtccat
     1261 ctgcttgagc aagaatatca aaaactggat aattatttgt aatgatccga attttcttgt
     1321 tcagtaaatg cgtcgccaat agttcgattg ttgtacctgg tcctaagaaa atcgtttctc
     1381 cctcgtgaat caaggaggct gctgtggcag caatttcttt tttttcttga atctgcagag
     1441 tggctttttc agtgtgagaa agttcttgat ctaaagtgta ggaaagactt tgagcccctc
     1501 catggacacg cagcagcttg cccgattttt ctaattcatc taaatctctg cgaacggtca
     1561 tatcagaaac atctaattga ttgatgattt cattaacggt aaggattcct tttttattga
     1621 ccatttctac gatagtaagc aatctttctt ttttcaacat tgtcttcacc tctaatttaa
     1681 ggataatcta tcatataaac ggacaacagt caatctaatt cgaacaaaag taaacattta
     1741 gggtggtttt tatgtttgtt acaatagatt ttattgctgt tttctggttt ttatgattat
     1801 ttgtgtttgt ttttgttgac aaatgttttg gatgcgttta caatgcaatc agttagaaag
     1861 agcgaaaact gattatagat ttgaggagag atgtacatgc ttaaattacc agaagatttt
     1921 atttttggcg gagccacagc agcctatcag gttgaaggag ccactaagga aggtggcaaa
     1981 ggcgctgttg cttgggatga ctttttagag gaacaagggc gattcagtcc cgatccggca
     2041 agtgattttt atcatcaata tgcaaaggac attgaattgt gtgaacgttt tggtgtaaat
     2101 ggtctaagat tatccattgc ttggagccgc atttttcctg atggagctgg gaaaccaaat
     2161 ccagaaggaa tcgcttttta tcatcgtgtg ttcgaagaat gtaagaaaag aaacgtaacg
     2221 ccgtttgtga cgttgcatca ttttgatacc cctaaacgtt tgtttgacca tggagatttt
     2281 ttgaatcgag aaacaataga agcatttgtt tcctatgcca ttttttgttt tcatgaattc
     2341 aaagaagtca aggtgtggag tacctttaat gaaatctatc cagttgcaac caatcaatat
     2401 ttgttaggtg ttttcccacc aggaatcaaa tatgatttta caaagatcgt cgcctgtctt
     2461 cataatatga tggttgctca tgcccgtgta gtgaactatt tcaaagaaaa cgaacttccg
     2521 ggtgaaattg gtgtagttca ctcattagag acgaaatatg cggcaacaga cgcgccggaa
     2581 gataagcatg ctgccttttt agacgatgca ttgtcgatcc gtttcttatt agatgctacc
     2641 tatttaggct attattcaac tgaaaccttg actgctcttg atgagatatg tgaagcaaat
     2701 caggccagct atcattttcc tgaagaagat ttcgttgaat tgaaaaaagc atccacgcgt
     2761 aatgactact tagggatcaa tcactaccaa tgccattttg tcaaagctta cgatggagaa
     2821 aatgcaatcc atcataacgg tacgggtgaa aaagggacct ctgtttataa agtgaaggga
     2881 atcggagaac gtatttataa agaaggaatt cctcgaactg attgggactg gctgatttat
     2941 ccagaaggtc tatatgactt gttgctgcga attaaaagcg attacccaca ttacaacaaa
     3001 atctatatca ctgagaacgg gatggggtat aaagatcagt ttgaagatgg cattattatg
     3061 gatcagccga gaatcgacta tttgagagtc tatttggaat ccttaagcaa ggcgataaca
     3121 gccggggtaa atgtgaaggg gtattttttg tggtcgctta tggatctttt ctcatggaca
     3181 aatgggtata acaaaaggta tggcttgttt tatgttgatt ttgaaaccca gaagcgttac
     3241 ccaaaagaat cagcttactg gtacaagttg gtcagtgaaa ccaaaacgat tatttaataa
     3301 gtgataatgg aggaagaaaa gatgaataaa gaggaattac aaatgcttgg ttttgagatc
     3361 gttgcatatt caggcgacgc tcgcagtaca ttattgaaat tattgaaaga agtaagacaa
     3421 ggaaactttg aacatgttga ttcggcgttg aaagaagccg acgaaaattt aacccttgca
     3481 cataattcgc aaacaaaaat tttagcggaa gaagcatctg ggaaagagat ggagatggga
     3541 ttcattttta tccatgggca ggatcattta atgaccactt tattgctgag agatctgatt
     3601 caagacttta ttgtactgta cagacagaat caaggatagg agaagaacgc tatggatgga
     3661 atcattaaac aaatcgaaaa agggaaacca ttttttgaaa aaatctcacg taatagttat
     3721 ttaggagccg ttcgtgacgg atttttaaca gcgatgccag ctattttatt ttcaagcatt
     3781 ttcattttga ttgctgcggt tcctgagatt tttggttacc aatggcctga atctgtctcc
     3841 acatggctat ggaaagtcta taattattcg atgggtgttg tagggttact cgtttcagca
     3901 accactgctc gctgcttggc tgattcgatg aatcgtcgct taccgaaaaa caaagtaatc
     3961 aacaccacct ctgtgatgct ggcctctgtg gtaagtttcc tgttgttaag cgtctctccg
     4021 attgaaggtg gattttcaac ggaatatatg gggacaaagg gactactggc ttcctttgtc
     4081 gctgcatttt taacagttaa tttatataag ttttgtgtgc tgaaagatat taccattaaa
     4141 atgcctaaag aagttcctgg aacgatttcg caaaccttcc gagatatttt tcctttctct
     4201 ttttcagtat ttgcggccgt tttaattgat ttaggcattc gacaaatctt ccaaatctca
     4261 tttgcagaag caatcattac ggtgctgcag ccgctattta cagcagctga cgggtactta
     4321 ggaatcgcta ttatctgggg agcgatggcg ctgttttggt ttgtcggtgt tcatggaccg
     4381 tcgatcgtgg agccggcaat tgcggcaatt atctatgcca atgtggaaac caatctgcaa
     4441 ttgttcaatt ccggtgaaca agcttctaaa gtactgacgg tgggtttagg gaattttgta
     4501 ggaactatgg gaggaactgg ggcaacattg gttgttcctt ttatcttcct actctttgct
     4561 aagtctaagc agttgaaggc agttgggaaa gcttccttta ttccagtaag tttcgctgtc
     4621 aacgaaccat tgctatttgc ggcacccatg attttgaacc cttatttttt tattccattt
     4681 ttgttaacac ctgttgtaaa cgtttgcctg ttcaagtttt ttgtcgatgt attgggcatg
     4741 aacagcttta tgtacgtttt gccttgggca actccagcac cgatcggttt ggttctagga
     4801 acgggcatgg gtatcttagc ttttgttcta gcagcggttc taatcgtcgt tgacttcctg
     4861 atctatctac cattttgcaa agcatacgat gctgtcttag tagagaaaga agcacaaaaa
     4921 gcagaggtga tcgcaaccga ggaaggtgct tctgccgatg tacgtgagga agtacctgtg
     4981 gcagcgagtc aagttatcag cgatgcaaat aaagaaatca atgtgttggt actttgtgct
     5041 ggcgcaggga caagtgggat gttagctaat gctttaaaaa aaggtgcatc tgaatcgaaa
     5101 gcaccgatca gtgcaatggc gggtgcttat ggttctcatt acgaaatgct gcaggatttt
     5161 gatatggtgg tcttagcacc gcaagtcaat tcttactatg atgatatcaa agaagacacc
     5221 gatcgcttag gaatcaagct ggttgcgaca aaaggagcag aatatatcgg attaacgaga
     5281 gatcctgaaa aagctgttca gtttattctg aaccaatttc aataaaggag gagccataat
     5341 gaaaatggga atttggttgc gtaaagctgt tttatttgca gctgtgttag gggctttggg
     5401 ggctgtttca aaaactgttg aagcatctgc cagcgaattt attcgcggag cagatatttc
     5461 gatcctgtca gatatggaaa aatctggtgc aaaatattat gaagacgata tttcaaaaga
     5521 tgccttagag attttaaaaa ataatggtgt caactatgtt cgactgcgtt tgtggcagga
     5581 tccttataat agtaatggag aaagttatgg agcagggaca aatgatctgg aaacgacgat
     5641 tgaccttgca aaacgagcaa aaaatctggg acttaaggtg ctgctggatt ttcactacag
     5701 tgatttttgg gttgatcctg ggaaacagaa tcttcctaaa gcatggcaag gtctgacctt
     5761 tgaagaaatg aatacggcat tgtacgacta tacaaagaac gttctgtcgg aaatgaagca
     5821 gctggacgtt tatcctgata tggttcagat cggcaatgaa ctgaatagcg gaatgctctg
     5881 gccttatggc aagtcttggg gagaaggcgg gggagaattt gatcgattgg ctgctttttt
     5941 gaagtctggt atccaagctg ttcgagacac tcaacctaaa acaactccag taatgctcca
     6001 cttagctgat ggtggcgata caggagcatt tacttggtgg tttgatgaaa tcacgagtcg
     6061 aggtgtgtca tttgatttaa ttggagtgtc gtattatccg tattggcacg gttcaatgaa
     6121 tgaacttcaa accaatatga atgcgatcag ccaacggtat ggtaaagaag tgatcgtagt
     6181 tgaaacagct tatgggcata caacagcgaa tgccgatact atgccaaatg cttttggtga
     6241 agccgaagca gctgcggggg gatatgaacc aacaccgaca ggacaagcag agtatttgct
     6301 ggatcttgcc gatcggattc aggcagtacc gaataatcgc ggggcgggct tcttctattg
     6361 ggaacctctt tggtacaacg gaaatgtgag ttgggcaaca caagcaggta tgaattatct
     6421 cagtgttcaa tccactatgg gaaacgaatg ggacaaccaa gcgatgtttg attttgctgg
     6481 aaacgccttg ccaagcttgc gtgcgtttaa acaagcaggg gcgcaaataa atctagttaa
     6541 aaatgcaagt ttcgaaagcg atggaccaac gaccagtcct tccaattggc aaacctggtt
     6601 tcaacaagga accgctaagg gtacgatcaa aacggaagcg ggcacttttt ttggggacta
     6661 caaactaact ttttggcagg atcaagcata cgaggcatca gcttatcaaa atgttagtgg
     6721 cataagcaaa ggaacttaca cattgagtgc ctatgtaatg tctgggggag agtttgatac
     6781 taatcagtta tatatcaaaa attatggtgg agcggaacta aatactgcgg ttgttaaaac
     6841 aagtgaatgg acaaaaatta caatcaaaga cattccaatt acaacaggtg tttgtgaaat
     6901 tggggtttat agcaaggctt caggaaatgc ttggacgaac gttgattttg tttcattggt
     6961 gaaacaatag actgcggatc gtttcgattc aagatcggag gttcccttca gccacatcgt
     7021 tagcgtagaa ggcaggaatc gaacctgcac ctcgcctttg ccaaaaataa ccagaaacga
     7081 tttccagtca tttttaccaa aacgagtaaa gcaccagact tcatctacac tttgtattat
     7141 gctaaagaga gttcaacgat ttcgtaagaa gcaatgaaaa aattgcaaaa agttgtgcag
     7201 ataacataaa gtttgtttaa gaaagggtaa ccttagaatt ccgtcgtgaa tatgatttga
     7261 gcacttagat ggatagaaaa aagttctcgg aaaacagttc gtttttcgag aacttctttt
     7321 tatgataaga atgaaacaaa ttaacttata ttatagtctc ttttggtagg gaaccatctt
     7381 atttttaatg aaaatcaagc attttagcta ttgaagaatg ttgatttata gggattcccc
     7441 ctccatatta tgttggctct ttattcccac tccactgttg ctggtggttt agaagtgatg
     7501 tcatacacga tacggttgac gtgggctact tcgtttacga tacgtacaga gattttttgc
     7561 aagacttccc atgggatacg ggcaaagtca gcggtcattc cgtcgattga agttacagca
     7621 cggataccga ctgtgtagtc gtaagtacgt ccgtcaccca taacaccgac agagcggatc
     7681 cctggaagaa cagtgaaata ttgccagata tcacggtcaa gtccagcagc tgcgatttct
     7741 tcacgcaaga tagcatcaga ttcgcgtacg atttctagct tgtcttcagt gatttcgcca
     7801 agaacacgaa taccaagacc aggaccaggg aatggctgac gccaaacgat tgaatcaggc
     7861 atgcctaact gagtccctaa ttcacggact tcgtctttga ataatgtgtt taatggttcg
     7921 atcaattcaa attgcatatc ttctggcagt ccacctacat tatggtgaga tttgatcgtc
     7981 tgtgctgttt ctgtaccaga ttcgataacg tcagtataca acgttccttg tgctaggaaa
     8041 gagacgcctt cttcaccagc aagttttgtt gcttcgtcat caaaaacata tacgaattca
     8101 ttcccaatga ttttacgttt ttgttctggg tcagatacac ctttcaactt gtctaagaag
     8161 cgatctcttg cattgacttt gatgatgttc aagccgaatt ttccgcctag actttccatt
     8221 acttgttccg cttcgccttt gcgtagcaga ccgtggtcaa caaagataga tgtcaattgg
     8281 tcaccgatcg ctttttgtaa aagaacccca acgacactag aatcaacgcc acctgaaaga
     8341 ccaagcaaga cttttttgtc accaacttgt tcacggattt tttctacttg catatcgata
     8401 aagttatcca ttgtccagtt accttcacag tgacaaacat caaaggcaaa gtggcgcagc
     8461 aattcgattc cgtattcgga atgacgtact tctgcatgga attggatacc ataaaaatta
     8521 cgtgttgtgt cttggataga agcaatcgga caatctttgc ttgttccgac tgtttcaaag
     8581 ccttcaggaa ctttagttac caagtcacca tggctcatcc atactgtttg ttgttttggt
     8641 gtttctttaa acaagacagc ttgatcgctt gttacttcta acaaggcttt cccatattcg
     8701 cggtttttag caggctctac ggaaccgcca agtttgtacg tgatcaattg cataccatag
     8761 caaatcccta atacaggaat acctaaattg aagatctcag gatcgatccc aaatgcattc
     8821 tcatcatata cactgtttgg tccgccagaa agaatgattc cctttggatt catcgctttt
     8881 acttcttctg cagtaatgcg gtggctcaat aattcggaaa agactccaag atcacgaata
     8941 cgtcttgtga tcaattggtt atactgacta ccgtagtcta atacgataat cttttcaacg
     9001 ttcgtcatat cggcaacgtt tgtcaaattt attaccccta tccctttaaa ttttatctca
     9061 aaatagtcaa actattttaa aatgctaata ttttcgcatg aaaatcgaat cgatgatatg
     9121 attttcagtt ttatggagaa ttatatcggc tcttcctcgt gtaggcaaga tatattcctg
     9181 taaatttttc aaattcacat ttttccatac atcttttgcc attttaaagg cttcttcacg
     9241 atctccgata gcaaaacgat aataataatt ctctggattt tggaaagccg tatccagtaa
     9301 cgcaccaaaa cgatccaaat accatttttc gatcagcacg ggatcggcat cgacatagac
     9361 agaaaaatca aaaaagtcgc tgacgtagat ttgctgattc gcaggtaatt gaagcgtatt
     9421 gatcccctca acgatcaaga tatcaggctg ctggatcaat tcgtacttgt ctggaatgat
     9481 atcatacaca tcatgtgagt aaacaggtac ttttatctct tcctgaccag attttacacg
     9541 gttcaagaaa tcgatcagca tctccatatc ataactttca ggaaatcctt tacggtccat
     9601 gattccacgc tcttttaata tacgatttgg ataaagaaat ccgtcagtcg tgatcagctg
     9661 aacgtttctt cgtttgaagg tacgagacaa aatcgtctgc agcagtctgg ctgttgtact
     9721 ttttccaacg gctacacttc cggcgatccc gataataaaa ggcggtactt ctacgtattt
     9781 atgaagaaat aaacctttac tcaagaacaa agattcaaat tctttcatat aaagataaat
     9841 cagatgagca agaggtacat agatatctcg aacatcctgc atggaaatgc ggtcattcaa
     9901 acttttgata ttatctagtt catcttgtgt caaaggtgct tgcccattac gataaaattc
     9961 tcgccattct tctcttgcca cacggtagta gttcattgga tcattcatat tagcctcctg
    10021 cgttctccca tcaatggaac tattttaaca caaaataaac gcaaacccca ccacttaaga
    10081 gagattgccg atctttttgt ataatcttta taatagaaag aaacggagtc ttattcttga
    10141 cttgcgcacg gatacataaa aggatagact gttgtcatga aagaaatgag aaggatggaa
    10201 gacatgacaa atcattacta ttctgaacgc ccagatacgg cgcacgattt tgaacaatgg
    10261 gcttttgagt taaaaggcag aacctttcaa tttgtaacag attctggtgt attttcacgt
    10321 gaaacagtgg attatggttc acgtgtcctg attgatgctt tcgattggga agagttacct
    10381 gatgaaggaa agatcttaga tgtgggatgc gggtatggac cgattgggtt agctttggca
    10441 tttgcgacac agcggtttgt tgaaatggtc gacattaatg aacgagcggt aagtctagcg
    10501 caaggaaacg caaagcgtaa ccaaatcgaa catgttgata tccatcaatc gaatatctat
    10561 gaagcagttc atgaagaaac ctatgcagct atcgtaagca atccgccgat ccgtgctgga
    10621 aaaaaagttg tacatgaaat tttgacaggc gcatatcctc ggttgaagaa gggcggtaca
    10681 ctgacaattg tgatccagaa gaaacaagga gcgccgagtg cgcaaaagaa aatggaagaa
    10741 acatttggta atgcagaaat cgtcacaaaa gataaaggat attatatcat caaaagtgtg
    10801 aaagaataac tagctgaaaa atagtggagc gacgaaagag tggaactggg cgtgcatgta
    10861 cgggtacgta tcagttcttt ttttgttgag aagtttttaa aaacaaagaa ctattttttc
    10921 ttcaaaaaga aatagtagga acagagtcgt tgttttttac gataaaataa ataagataca
    10981 gaacttgtat agaaggctgc caagtcggta gataaaggag gtttttatca aaaaacatac
    11041 tttccttttt tctctattct tttcttgggg gttttggtac actgataggg aatttagata
    11101 gaagggagcc aataggatga agctgaccat cagagatatc gcagaaatgg caggcgtatc
    11161 agtaacaact gtctcacaga ttttgaataa caaaggaagc agatttagtg ataagacaag
    11221 aaaaaaagtg ttgtcgatcg tgaatgaaca tcattataag cccgattatt tcgcttcaaa
    11281 tgtgatcaat cgacattcaa agaccatcgg aatgatcgtc cctgatgtca ctgatttctt
    11341 cttctccaaa ctgatcgaag gtgtagagag ctatttgaat cctttgggct atgtgatcat
    11401 gttatgcaat tctcgtcata gccaagaaaa tgagatcaag tatttacaag agctttccca
    11461 ccgctcagtg gacggaatct tgctggccac accaaatatt ttacctgaga aatatgcatt
    11521 agacagcggt ttttatcaaa aaatgccaat cattttaatc gatcgcggat tgaatcgtcg
    11581 ggataacgga cggcttatcg taaaggaata tgagggcgcc tatcaagctg tttcgctgtt
    11641 tattgaaaat ggccatacga agatcggcat gctgaaggaa accactggat actatcaatt
    11701 agaagaacgt ttcaacggat atcgtcatgc gctgaaagat catggcctgc cttttaatgg
    11761 gaaatttgtt gaacatggag agttgactgt ccaaggtgga tatactgcat caaaaaaatt
    11821 actcaaacat aaagatatca cggctatttt ttgcgggaat gatgccatgg cgatcggatg
    11881 ctatcaggcg atcgatgaat tgggcaaaaa aatcccagaa gatatctcag tcataggatt
    11941 cgatggatta aagctgtcag aatacatgat tccgcaattg acgacagtgc agcagccaag
    12001 ttttgatatt ggattttatg ctgcacgttt cctgatcgat acgatcgaat ttcctcaaag
    12061 aaaagttccg aacaaagtgt tcgaaacaaa attaattatt cgtgagagcg taaaagtatt
    12121 gacaaagggc taactcggcg gtatattgct tatgtaagca tttacaaagg ctagttagtg
    12181 ctttttttat ttttagtaaa ccagtttact aaagtggttt acctttccta aaaataatgt
    12241 ataataccga atgaagacaa ggaggatcag gcaatgcgaa tggtggatct gattgaaaaa
    12301 aagagggatg gaaacgagct gtcgaaagag gaaatcgagt acatcgtcac gaactatacg
    12361 aatggaaaga ttccagatta tcaagtcagt gcattattga tggcaatttt ttatcaagac
    12421 atgacaaatg aagaaatcac gaacttaaca ttggcgattg ctaattctgg tgatgtcatc
    12481 gatttgagtt ctcttgaagg aataaaggta gataagcatt cgacaggtgg cgttggtgac
    12541 acgaccacat tgattttagc ccccctagta gctagtgtcg gagtgacagt ggctaaaatg
    12601 tctggacgcg gtctaggtta cacaggtggt acactagaca agctagaagc aattcccgga
    12661 tttcagatcg agctttcgga tgaagaattt gtacgcattg ttaatgaaag taaagtagcg
    12721 gtaattggtc aatcaggaaa cttggcaccg gcggacaaaa aattgtatgc cttgcgtgac
    12781 gtcacagcga ccgttgattc tcttccgctg attgccagtt cgattatgag taaaaaaatc
    12841 gcggcaggag cagatgcaat cgttttggat gtgaccactg gagacggtgc tttcatgaag
    12901 aacatcgaag atgcaagacg tctggcaaag accatgacga gcattgggaa actggctaac
    12961 cgagaaacag tggcggttat ctcagatatg tcagaacctc ttggcgaagc tatcggaaat
    13021 agtctagaag ttgtcgaggc aatcgaaaca ttacaaggaa atggtccaga agatctagta
    13081 gaaatgtgct acgccttagg aagccaaatg gttgttcttg ctggcaaagc taagacaacc
    13141 gatgaagcaa gaacgttgct tcaagaagct ctggaatcag gtaaagcgtt agcaaaattc
    13201 aaagaaatga tccaaaatca agggggagac ccagcgatcg tggaacatcc agaacgaatt
    13261 ttgactgcac gctacacaat ggagcttcct gctaaacaaa gcggagttgt gtcaaaaatc
    13321 gtggcaaatg aattaggaat tgctgcaatg atgctaggtg ctgggcgtaa aaccaaagaa
    13381 gaagatattg atcacgctgt tggattgaaa ctgcataaaa aaattggtga cactgtgaca
    13441 aaaggtgagt cactattgac gatctatagt aacgacgaag aaatcacttc tgtcattgaa
    13501 ttattatata aaaatattga aattggtgaa tcggcaatga agccaacgtt gattcatgac
    13561 atcatcacag aataaaggaa aaaagcggac tttaccgttt taaagaaaag gggaaaagaa
    13621 atggaactaa accgaatgat cgaccatact attttgaaag cagacgcatc taaagaagct
    13681 gtgatgcaaa ttatcgaaga agcaaaaaaa taccattttt attctgtctg catcaatcca
    13741 gcatgggttg cgctagcgaa agaacaatta caaggtgagc cagtagccgt atgtacagta
    13801 atcgggtttc ctctaggagc aaacacaccc gagacaaaag catttgaaac aacagatgcc
    13861 atcaataacg gtgcagatga agtcgatatg gtcatcaata tcggtgcttt gaaatcaaag
    13921 gatgatcaac aagtccaaaa agatatcgaa gcagttgttg aagcagcaaa agatcgtgcg
    13981 cttgtcaaag ttattattga aacatcgtta ttagatagag aagaaatcat ccgagcttgc
    14041 gaaatagcaa aagctgcagg cgctgatttt gtcaaaacat caactggttt ctcaacaggc
    14101 ggagcaaagg tagaggatgt ccgtttgatg cgtgaaactg taggaccaga aatgggtgtc
    14161 aaagcttccg gcggtatcca taacgaagaa gaagcaatgg caatgatcga agctggtgct
    14221 acaagaatcg gaacaagcgc aggagtagca atcgtatctg gttcaactgg tgaaggctat
    14281 taattttttc aaaggagaag ctcatggcag aactcaaaca agaatggatc aacacagcta
    14341 ttgaagcgtt agataaagcc tatgttcctt attcccattt tccggtaggc gcttgtctcg
    14401 taacggaatc aggcaagatt tatcaaggca tcaacattga gaatgcatca tttggattaa
    14461 cgaattgtgc cgagcgcaca gcttttttca aagcagtatc tgaaggagaa aaaacattta
    14521 cgcatctagt cgtagcgggg cacacccccg atcctatctc tccttgtggt gcatgtcgac
    14581 aagtaatggc agaattctgt tcccctgata tgccggttac gctagtagga gacaatggtg
    14641 tgacgaaggc aacgaccgtt cgtgcactgc tgccttatgc atttactgaa aaagatctat
    14701 aactcatgtt cattcagtca gctgactgtt gaaaaataaa acaattattt taggaggctt
    14761 tacagaaatg aaaaaagcaa aattatttgg tttaggtgct gtcgcactag cagcagggtt
    14821 atttttaggt gcatgcggca acaacggctc tactgattca tccggtggca aaagctcatc
    14881 agacacaaca actgcagcat tgatcacaga cacaggtggt gtagacgacc gttcattcaa
    14941 ccagtcagct tgggaaggac tagaaaaatg ggggaaagat caaggacttt cacgaggaaa
    15001 tgatggcttc caatatttcc aatcttcaaa tgaatcagat tacatcccaa atattgacca
    15061 agcattgaat gctggattca aaacgatttt tggtattggt tataaactaa aaccagcgat
    15121 ccaagaacaa gcaacaaaca atacaggtac gaactttgtt attatcgatg atgtcatcga
    15181 tggattagat aacgttgtat ctgcaacttt caaagacaac gaagcttctt atcttgcagg
    15241 tgttgcagca gcttatacga ctgaaacaaa cgtagtcggc tttatcggcg gtgtaaaagg
    15301 tgaagtaatc gatcgttttg atgctggatt caaagccggt gttgatgcag gtgcgaaaga
    15361 attaggaaaa gaaatcaaag tattgaatca atatgctggt gacttctctg ctccagataa
    15421 aggacgttca attgctcaag gtatgtatgc acaaaacgca gatatcatct tccatgcttc
    15481 aggcggtaca ggtaacggtg tattccaaga agcaaaatca ttgaacgaat caggcgacaa
    15541 aaaagtttgg gttatcggtg ttgaccgcga ccaatcagac gaaggcgaat acacattaaa
    15601 cggcgaaaag aaaaacttca cattgacatc tacactgaaa gcagttggaa cagtagtaga
    15661 agatttggca caaaaatcag cggacggtaa attccctggc ggcgaacaca ctgtttatgg
    15721 attgaaagaa gacggtgttg gtctaacaga aggacaactt tctgacgaag cgaaaaaagc
    15781 agttgatgaa gcaaaagaaa aaatcatttc aggtgacgta aaagttccag aaactcctga
    15841 agaaaactaa aaccatttct atagccttgt tagacacatg tttgacaagg ctatggtttg
    15901 attagaacaa gaattgttca tttatccaag ctgccttgtg acagtttgga taagggaaca
    15961 actccctgaa gtaatgtttg tttcaaaaga agaacgctca ctaagcgtga atcttagtca
    16021 atcgttgccc tagatagaaa tcgttaggat gtgaaaaaaa ggtggttcaa gaaaatattg
    16081 tcatagaaat gcagaatatt accaaagaat ttggaacatt caaggcaaat gacaacatca
    16141 atttacaagt aaaggcagga gaaattcatg cgttgcttgg agaaaacggt gctggcaaat
    16201 ctacattgat gaacgtgctt tccggattat tagagccgac atcagggaaa attttgatgc
    16261 gtgggaaaga agtaaagatc acaagtccga ccaaagccaa ccaattaggg attgggatgg
    16321 tccatcagca ctttatgctt gttgatgcct ttactgtaac agaaaacatc gtgttgggaa
    16381 gcgagcctag tcgcgcaggg atgcttgacc ataaaaaagc acgaaaagag atccaaaaag
    16441 tttctgaaca gtatggattg tcagtcaacc cagatgctta cgttcgtgat atttcagttg
    16501 gaatggaaca acgggtagaa attttaaaaa cactttaccg aggagcagat gtactgattt
    16561 ttgatgagcc gacagctgta ttgacccctc aagaaattga tgaattaatc gtgatcatga
    16621 aggaattagt caaagaaggc aagtcgatca ttttgattac gcataagtta gatgaaatca
    16681 aagcagtagc tgaccgctgt acagttatcc gccgtggaaa aggaatcggt acagtcaacg
    16741 ttaaagacgt aacctcacaa caattagccg atatgatggt tggaagaacg gtttcattca
    16801 aaacgatgaa aaaagaagcg aagcctcaag aagtcgtttt gtctattgaa aatctagtgg
    16861 tgaaagaaaa tcgtggatta gaagccgtga aaaacttgaa cttagaggtt cgtgctggcg
    16921 aagtacttgg tatcgctgga atcgatggaa acgggcagtc ggagttgatc caagctttga
    16981 ctggtttgcg aaaggcagaa agcggacata tcaagctaaa aggggaagac atcactaata
    17041 aaaaaccccg aaaaatcact gaacatggtg taggacacgt gccagaagac cgtcataaat
    17101 acgggttagt cctagatatg acattatctg aaaatatcgc actacaaacc tatcatcaaa
    17161 aaccttacag taaaaacggc atgctgaatt attcagtaat gaatgaacat gccagagaat
    17221 tgatcgaaga atatgatgtt cgaacaacga atgaacttgt tcccgcaaaa gctttatcag
    17281 gcggaaatca gcaaaaagca attatcgctc gtgaagtcga ccgagatcct gatctgttga
    17341 ttgttgcaaa tccaactcgt ggactggatg taggtgcgat cgaatttatt cataaacgtc
    17401 tgatcgaaca aagggacaaa tacaaagcag tgttactgat cagtttcgaa ttagaagaaa
    17461 ttttaaatgt ttcggatcgt attgctgtta tccatgaagg agaaattgtc ggtatcgttg
    17521 atccgaaaga aacatctgaa aatgaattag gtctattgat ggcgggctat accttagaag
    17581 aagcacgaaa agagttagaa aagggggctg gcgcacatga atgatcgcag cgaaaaattc
    17641 cgtaatttat tagtgcctgt actttcagtt gttttaggat tgatcttagg cgcgatattg
    17701 atggctgctt ttggttttca gcccatccaa ggttattctt ctatgctaga tgcagccctt
    17761 ggttcgcaaa gagggatagg tgaaacgtta aggcaagcaa cgccgttgat ttttacagca
    17821 ttaggttttt ctgtagctaa ctcagctggg tttttcaata ttgggctttc tggacaagca
    17881 ctttgcgggt ggatcgtcag tgtctgggtg gcacttgcgt ttccagatct gccaaaagtt
    17941 gttttgcttc cgttatgcgt gatcttaggt gccttagctg gtgcgatggc agcggctgtt
    18001 ccaggtttac ttcgagcatt ttttggaaca agtgaagtga tcgtaacaat catgatgaac
    18061 tatatcttat tatacgtaag cacatttgct ttacatgaag tgatgcctga aagctatcgc
    18121 tcaagtttgg actcttccaa tatgatcagt caaaatgcct cactgcggtt accatggtta
    18181 acacaagctt ttggcggctc tcgcgtaaac tcaggattat ttttagcaat catcgcgctt
    18241 attttcgttt ggctgctgat gaagaaaacg actttaggat ttgaaatccg ttctgttgga
    18301 ttgaatcctt ttgcttctga gtatgcagga atgagtagta aacgtacgat cgttttgtcg
    18361 atggtcattt ctggcgcttt ggcagggctt ggcggtgtgg ttgaaggatt aggaacgtat
    18421 caaaacttct ttgttcaaac gacttcgcta tctattggat ttgacggaat ggctgtttcc
    18481 ttgcttggtt ctggatcagc aatcggtatt cttttatcag cgatcttgtt cagtattttg
    18541 aagatcggtg gacttggcat gcagacagga gcaggtgttc cgtttgagat cgtcaatgta
    18601 tcgattgctt tgattatctt ctttgtcggg atcaacttcc tgattcgttt cgtcatggct
    18661 aaagtcttcc aagggaaaaa acaagaagag atcgttgcga caatagaatc gaaaccaacg
    18721 aatcaaaacc atgaaggggg cgaactataa tgtcgactat cgaattaatt gccttgatcc
    18781 ttacttctac actggtttat tcaacaccgc taattctaac gtcactaggc ggaacttttt
    18841 ctgaacgaag cgggatcgta aacgtagggc tagagggaat catggtcatg ggtgctttta
    18901 gttccatcgt tttcaacttg acgatgagtc catcacttgg ttctatgaca ccatggatcg
    18961 ctattttagt gggtggcgtc gtaggtatcc tattttctct gattcacgca gtagcaacag
    19021 tcagtttgcg tgctgaccat attatcagcg ggacagtaat taatctgatg gcacctgctt
    19081 taggtgtttt cttgatcaaa gcatggtatg gtaaaggtca aactgataac atcacgcaga
    19141 atctggggta tttttctttc ccaggattag cagatattcc ggtcattgga ccaattttct
    19201 ttaaaaatac attcttacct gcttattgtg ctattttgat tgctgtccta gcttgggtga
    19261 tcatcttcaa gacgaaattc ggcttgcgcc tccgttcagt tggtgaaaat cctcaagctg
    19321 ccgacacatt aggtatcaat gtatatgcta tgcgttattc aggcgtactg atttctggct
    19381 tgttaggcgg tatgggcggt gctgtttttg ctcagtcgat ttccggtaac ttttcagctg
    19441 gtacgatcgt tggacaaggg ttcatctcca tggctgctat gatctttggt aagtggaatc
    19501 ctttaggggc aatgggtgcc tcattgttct ttggttttgc tcaaagcttg agtatcattg
    19561 gcgcacaatt accagttatt tcttcgattc cgccagtatt gctgcaaatt gctccatatt
    19621 tgctgacaat cattgtgctg gttgttttct tagggaaagc ttctggtcca aaagcaaacg
    19681 ggaagaacta tatcaaatca aaataatctt ttagcgaata aaaagggtgg gttacgggaa
    19741 gtgtttttcg tctcgccctt tttgttttaa aggcaataaa aataaaaaga aagaaggaat
    19801 aatcatgttt aaacgcgtac atctgatcgt catggattca gtaggaattg gagaagcacc
    19861 agatgccgat aagttcggtg atgttggttc tgatacatta ggacacattg cgaaagaagc
    19921 aggattgaac gttccacatt tagagcagct tggtttagga acgatccgtc ctcttgaagg
    19981 tgtggaatca gtgaaagatc atcaaggcta tgcgacgaaa ttagaagaag tttctgtagg
    20041 gaaagatacg atgacaggcc actgggaaat catgggattg aatatcaaaa ctccatttcg
    20101 tgtgtttcct aatggattcc ctgatgatct gatcaaacaa atcgaagaat tttctggccg
    20161 taaagtcgta tgtaacaaac cttatagcgg aacagctgtt attgacgatt acggtgaaca
    20221 ccaaatgaaa acaggcgatt taattgtata tacttctgcc gatcctgtcc ttcagatcgc
    20281 ggcacatgaa gaaatcattc ctttagaaga attatatcgg atttgccaat tcgttcgtga
    20341 tataacaaaa gatgatccgt atatgattgg ccgaatcatt gcacgtccgt acgtgggtga
    20401 accaggagac ttcacacgaa caagcaatcg ccatgattat gcgttgaatc cattcggaca
    20461 cacagtcctt gattctttga aagaagcagg aaaggacgtg attgctgttg gaaagatcaa
    20521 cgatattttc aacggacaag gaatcactga atctgtccgc acgaaaagca atatggatgg
    20581 cgttgaccag ctgctgaaag ttatgaaaaa cgatttttca ggaatcagct ttaccaattt
    20641 agtagatttt gatgcattat acggtcatcg tcgggatgta gtcggctatg cgcatgcgat
    20701 tgaagaattt gacttacgaa ttccagaatt gcttgaagcg atggaagaag acgacttgct
    20761 aatgattaca gccgatcacg gaaacgatcc gacgtttact ggtaccgatc atacgcgaga
    20821 atatgtaccg ttattggttt acagtaaaaa aatgaaagaa caaggggcat tgcctcaagg
    20881 atattattca gatatttcag caacgattgc tgagaacttt agtgtttctt cgactgaaaa
    20941 tggcgaaagc ttcttgaaat tattaaaata atctttttaa ataggagaaa gcaaatgacc
    21001 aagttaagcg agatgttaca agaaacgacc cagtttatcc ttgataaagg agtaaaagaa
    21061 attgattttg gtttgattct aggttcagga ttaggtgaat tagcagatga aatcgaagat
    21121 gctgtaatga tttcttatga tgagatcccg ttctttcctg tttcgacagt agttgggcat
    21181 gcaggaaagc tagtttatgg gtctctggca ggcaagaaag tgttagccat gcaagggaga
    21241 ttccactact atgaaggtca ttccatgcaa acagtgacct atccagtacg tgtgatggcc
    21301 ggactagggg cccattcagt cattgtgact aatgcatgtg gtggtgtcaa cgaatcattt
    21361 gtaccaggag atttgatgct gattaccgat catatcaatt ttactggtga aaatcctttg
    21421 atcggtccga atgaagatgc aatgggccct agatttccag atatgagtca agcttatacg
    21481 cctgactatc aagcaacagc aaaagcagca gcagaaaaac taggtttgga tcttaaagaa
    21541 ggcgtatata tgggctattc tggaccaact tatgaaacgc ctgcggagat ccgaatgtct
    21601 cggacaatag gagccgatgc agtagggatg tcgactgttc cagaagtcat cgtagcagct
    21661 cacagcggat taaaagtgtt aggaatctct tgtattacca acttagcagc aggtatgcaa
    21721 gcgaatctga gccatgaaga agttgtagaa acaactcaga gagtcaaaca atcttttaaa
    21781 gcattggtta aagaaacatt gacattattg taataggagg aacaataaaa tgagtgtgca
    21841 tattgaagcg aaagaaggcg agatcgccga taagatttta cttccgggag atcctttgcg
    21901 agctaaatat attgcggaga cttttttgga agatccagtt tgttacaatc aggtacgcgg
    21961 tatgttaggc tttaccggca aatataaagg agaacgtatt tctgttcaag gaacaggaat
    22021 gggaatgcca tcagccacca tctatgccca tgaattgatc cagtcgtatg gtgtaaagaa
    22081 attgattcga gtaggtacat gcggtgcatt gtcaaaagac gtccatgttc gtgatttagt
    22141 actagcacaa ggtgcagcga ccagttcttc gatgatcgaa aaaaatttcc aagcctttca
    22201 ttttcctcca atcagtgatt tcaatctatt actgaaagca tatgagatag ctaaagaaaa
    22261 gggctatacg gttcatgtag gaaatgttct ttcggaagat tctttctaca aagatgattt
    22321 gacagagacg ttccaattag ctgaacttgg cgttttagga gtggaaatgg aagcagcggc
    22381 tctttattac ttaggcgcga aataccatgt gcagacatta agtttgatga ccgttagcga
    22441 ccatttgatc accggtgaag aaacaacagc tgcagaacgt caatctacgt tcaatgaaat
    22501 gatcgaagta ggattggaaa cagcgatagc agaataagaa ggaaatgaaa aagctgccct
    22561 gcattaagta ataagaacat ccaagcaaaa atagctcctc atgtttttga cttggctgga
    22621 cttattattg caaatgtaag cttttgaaca ccgtttacca agaggttgtg aatctgccgt
    22681 ttaactctga gtcacaagga acaatttcaa aaaacagctt ttcatgtttg atgaatattg
    22741 tgacttgtga ccgagaagtt ggcaggagaa aaccgtttat acgaaaaaag ggactgtgac
    22801 aaatcgtgtc acagtccctt ttttatagtg ttttttatag gtagtatttt ttagcaactg
    22861 ttaagtcatc atttaattca taaacaagtg gttgacctgt tggaatttca agatccatga
    22921 tgtcttcgtc agagatacct tcgatatgtt tagctagggc gcgtaatgag ttaccatgtg
    22981 cagctactaa aacagttttg ttgtctagta atgctggagc aatttcatct tgccagaatg
    23041 gcaaagcgcg ttctaatgtc actttcaagt tttctccacc aggaatatcg cgtttgtcta
    23101 acattgcgta acgacggtca tttgctgcag aaccttcgtc agtttcttcc attaatggag
    23161 gaagagtatc gtaagaacga cgccagatgt gcacttgttc gtcgccgtat ttttcagctg
    23221 tttctttttt gttcaaacct tgtaatttac catagtgacg ttcgtttaag cgccatgatt
    23281 tgatttgtgg tacccaaagt tgatctgaat attctaagat caagttacat gttttgattg
    23341 cacgagttaa aacagaagtg taagcaacat caaattcgat tccagcttct ttgattttgc
    23401 gtccgccttc ttttgcttct tcgattcctt ctggtgctag atttacatca gcccaaccag
    23461 taaattggtt caatgcattc cattcactaa gaccgtgacg agaaaaaact aattttggca
    23521 tgtttagctc tccttttaag ataggtttat atttctgaaa ttttcagttc tgttttattg
    23581 tacaattttt tggaagagat ttccatcgaa aaattagata agattctatg agaaaacaag
    23641 tagagaatat aaaaaaacga acagtgccca cgcaactgtt cgtttttagg tattagatgc
    23701 ataattgctc gatttctttt tcaggtaaat tgatatattt ataacatgtt ccaactgaaa
    23761 caccgcattt tgaagaaata aattggatcg tttctttttt ttcataatag agacgtcgga
    23821 tttttttgat cgtttttgca tcgatttttg gtcttccgcc gatttttcct tttttacgag
    23881 cttcatctaa tccaactaat gtacgttctt tgatcaatgc gcactccatg tttgctaggt
    23941 tttccattaa ttggaaatag atttttccca tttcgcgcgt atcgattcct tcatcaagac
    24001 taatcaagtg cagcccgcga tctttgaata attgcgtgag ttctgttaat tgccgcgtag
    24061 atttgcctaa tcgatgaagt tggcaaatga ctagtgcatc gccttgttgc atgtcagcga
    24121 tcactgactc caaatgaaca gcagtagaat cattttgttc cacttcatat gtctcatgga
    24181 aaatttcttg acaaccaaag tcagataatt gatcaacctg agttgttaaa tcaacgtcat
    24241 ttatggttgt gcgtgcataa ccaataattt tcatggtgat tcctttctag cagtgatttt
    24301 ctaactggat ataacagtaa aaatgtagca taaagtacgt caaaaagata gttttttcgc
    24361 aaattttccg ctgtcttttt ttattggatg atcaagcagt ttttctttat ttacgacgga
    24421 ttgcgtcaag aatctcaacg cctttttctg agccgacaac tactttagaa accatgttta
    24481 ggaaaagccc atgttctact accccaacaa gttcatctaa ataggtagct aagctttctg
    24541 gctgttcgat gacttctaga tgcagatcaa tgatgtaatg accaccatct gtggttaaga
    24601 cttctccgtt ttcgtctgta cgcaagacgg gttggaatct tttttcttca aaaatatgaa
    24661 gtagctgttg ggagccataa gggatcactt caactgggag tgggaacttc ccaagtttat
    24721 cgactaattt agaagaatca acgatccaaa tcgtttcttt tgagtacgta gcgactattt
    24781 tctcgaaaag caaagcagcg ccgccgcctt tgatcccttg aaaatcagca ctgatttcat
    24841 cagcaccgtc tattgtcaaa tcgactacgg ggacttcatc aatactcttt aacggtattc
    24901 ctaatttttc cgcttgttct tttgtcgcat ttgaagtagt aactcctgtg atacgtaaac
    24961 cttcttcacg catacggcga ccaatctctt ctaccatata ataggcggtt gaaccggtcc
    25021 cgagacctac gatcatcccg tcctttacga atttcgcggc ttcaatgcca gctaattgtt
    25081 ttaaattcat ctttgcgtcc accttttttt agtttgagca tcgtgctttc ctcactattt
    25141 tagcgtgatt tacggtaaaa agataccatt cttttttatt ccaataaagc tttttcaaaa
    25201 aaaattgcat ctcttgttga catgtttttt cattcgtgat attctaacaa aggtgcttta
    25261 tctacaggtt tctgtgaaga aacgtgctga ctgtttatca aagcatattt gataaggatg
    25321 cagacattgc atttattttt tatcacaaaa aaagaaccac ctggatgtgt ggaactagac
    25381 gcaaatcgtg ggaaggagga aacaaggaat gcctacaatt aaccaattag tacgtaaacc
    25441 tcgtaaatca aaggtggaaa aatctaattc acctgctttg aacaaaggat ataacagctt
    25501 taagaaaact caaactaacg taaactcacc tcaaaaacgt ggggtagcaa ctcgtgtggg
    25561 tacaatgaca cctaaaaaac cgaactcagc tttacgtaaa tatgcacgtg ttcgtttgtc
    25621 aaacttaatt gaagttactg cttatatccc agggattggt cataacttac aagaacacag
    25681 tgttgtatta ttacgcggtg gtcgtgtaaa agacttacca ggggtacgtt accatatcgt
    25741 tcgcggtgct ttagatactg ctggtgttaa cgaccgtaaa caaagccgtt ctaaatacgg
    25801 aactaaaaaa cctaaagctt aattttaatt attaaacaaa tgaaacttgc ttctactata
    25861 tagaagtaat tactatgaac aatatttcgg aaggaggagt tacggatgcc acgtaaaggt
    25921 cctgttgcaa aacgtgatgt tttaccagat cctatttata actcaaaatt agtaactcgc
    25981 ttgatcaacc gtgtaatggt tgacggaaaa cgcgggattg cagctaacat tatctataat
    26041 gcctttgact tgatcaaaga atctacaggt aacgatccat tagaagtgtt tgaacaagca
    26101 atgaaaaacg ttcaacctgt tcttgaagtt aaagcacgtc gtgttggggg ttcaaactac
    26161 caagtaccag ttgaagttcg ccctgaacgc cgcgttactc taggtcttcg ttgggtagta
    26221 aactacgctc gcttgcgcgg tgaacacaca atggaagaac gcttagcaaa agaaatcatg
    26281 gatgctgcaa acaacacagg tgcttctgtt aaaaaacgtg aagacactca taaaatggct
    26341 gatgccaacc gtgcgtttgc tcactatcgc tggtaagatt ctctctgttt ggtcggcttt
    26401 tataagtcga cctcagatag tgtccttatt tttagcaact agatagtaaa gagaggagaa
    26461 acaaggagaa tgaccagaga attttcttta caaaacactc gtaatatcgg tatcatggcc
    26521 cacatcgatg ctggtaaaac gactgctact gaacgtatct tgtactatac tggtaaaatc
    26581 cataaaattg gtgaaactca tgaaggagct tcacaaatgg actggatgga acaagaacaa
    26641 gaacgtggta ttacgatcac ttctgctgct actacagcac aatggaaggg tcaccgaatc
    26701 aacatcatcg acacaccagg acacgtagac ttcacagttg aagttgaacg ttcattgcgt
    26761 gtacttgatg gtgctgtaac tgttcttgat gcacaatcag gtgttgaacc tcaaactgaa
    26821 acagtttggc gtcaagcaac aacttatggt gtacctcgta tcgtatttgc aaacaaaatg
    26881 gacaagatcg gtgctgactt cttatattca gtatcaactt tacatgaccg tttgcaagca
    26941 aacgctcacc caatccaatt accaattggt gcggaagacg acttcacagg aattatcgac
    27001 cttgtaacaa tgaaggctga aatgtataca aacgatcttg gaacagagat cgaagaaaca
    27061 gaaattcctg aagaataccg cgaattagct gaagaatggc gcgaaaaatt ggttgaagct
    27121 gtagctgaaa ctgatgaaga acttactttg aaatacttag aaggtgaaga aatcactgaa
    27181 gctgagttaa aagaaggtat ccgccgcgca acagttaacg tagaattcta cccagtacta
    27241 tgtggttcag catttaagaa caaaggggtt caattactat tggacgctgt tcttgattac
    27301 ttgccatcac cgttagatat cccagctatc aaagggattg accctaaaac tgatgaagaa
    27361 gtagaacgtc ctgcagacga cagcgctcct ttctcagctt tagcatttaa agttatgact
    27421 gacccattcg taggtcgttt aactttcttc cgtgtgtact ctggtgtttt acaatcaggt
    27481 tcatacgtac aaaacgcaac aaaaggcaaa cgtgaacgtg ttggtcgtat cctacagatg
    27541 catgccaact ctcgttcaga aatctctgaa gtttacgctg gagatatcgc tgctgctgtt
    27601 ggtttgaaag acacaactac tggggacaca ctatgtgatg aaaagagtct agttattctt
    27661 gaatccatgg aattcccaga accagttatc caagtcgcta ttgaacctaa atcaaaagct
    27721 gaccaagata aaatgggtgt ggctttacaa aaactatctg aagaagatcc tactttccgt
    27781 gctgaaacaa acgtggaaac aggcgaaaca atcatcgctg gtatgggtga acttcactta
    27841 gatatcatcg ttgaccgtat gcgtcgtgaa ttcaaagttg aagctaacgt aggtgcgcct
    27901 caagtatctt accgtgaaac tttccgtgct ggcactcaag ccgaaggtaa gtttgtacgt
    27961 cagtctggtg gtaaaggtca atacggtcac gtatggattg aatttacacc aaatgaagaa
    28021 ggtgctggtt tcgaatttga aaatgcgatc gtcggtgggg ttgttcctcg tgaatacatt
    28081 ccagctgttg aaactggttt gaaagatgct atggaaaatg gtgtcttagc tggctatcca
    28141 ttagtagata tcaaagctaa actttacgat ggttcatacc atgatgtcga ttcaaatgaa
    28201 actgccttcc gtgttgctgc ttctatggca ttacgtgcag cagctaagaa agctaatcca
    28261 gtaatccttg aaccaatcat ggctgtagaa gttgttatcc ctgaagatta tttaggtgat
    28321 gttatgggtc acgtaactgc tcgtcgtgga cgtgttgaag gtatggaagc tcgcgctggc
    28381 ggccaacaag ttgttcgtgc gatggttcca cttgctgaaa tgtttggtta tgctacaact
    28441 cttcgttctg ctactcaagg tcgtggtaca tttacaatga catttgacca ctacgaagat
    28501 gtaccaaaat cagtacaaga agaaatcatt aagaaaaacg gcggaaaagc tgaataattt
    28561 cttgaaaccg gatagtcctg caaagagatt atccaaagag actatatttt taatatagtt
    28621 tcgtgtaaaa taattatcga tgatatgggc atgtggtgta ccttgtgtac atcatatacc
    28681 tatcagacaa ataaaaaata tattgtattt ttaggaggac attttaaaat ggcaaaagaa
    28741 aaatttgacc gttctaaacc acacgttaac attggtacta tcggacacgt tgaccatggt
    28801 aaaactacat taacagctgc aatcacaact gtactatcta agaaaaacgg cggccaagct
    28861 atggcttacg atcaaatcga tggtgctcca gaagaacgcg aacgcggaat cacaatctca
    28921 acagctcacg ttgagtatga aacagataca cgccactacg ctcacgttga ctgcccagga
    28981 cacgcggatt acgttaaaaa catgatcact ggtgctgctc aaatggacgg agctatcttg
    29041 gtagtttctg ctgctgacgg cccaatgcct caaactcgtg aacacatcct attgtctcgt
    29101 caagttggtg ttccttacat cgttgtattc ttgaacaaag tagacatggt tgatgacgaa
    29161 gaattactag aattagttga aatggaagtt cgtgacctat taacagaata cgaattccct
    29221 ggtgacgatg ttcctgtagt tgctggatca gctttgaaag ctctagaagg cgacgcttca
    29281 tacgaagaaa aaattcttga attaatggct gcagttgacg aatacatccc aactccagaa
    29341 cgtgacaacg acaaaccatt catgatgcca gttgaagacg tgttctcaat tactggacgt
    29401 ggtactgttg ctacaggtcg tgttgaacgt ggacaagttc gcgttggtga cgaagttgaa
    29461 gttgttggta ttgctgaaga aacttcaaaa acaacagtta ctggtgttga aatgttccgt
    29521 aaattgttag actacgctga agctggagac aacattggtg ctttactacg tggtgttgca
    29581 cgtgaagaca tccaacgtgg acaagtttta gctaaaccag gtacaatcac acctcataca
    29641 aaattctctg cagaagtata cgtgttgaca aaagaagaag gtggacgtca tactccattc
    29701 ttcactaact accgtccaca attctacttc cgtacaactg acgtaacagg tgttgttgaa
    29761 ttaccagaag gaactgaaat ggttatgcct ggcgacaacg taacaatgga agttgaatta
    29821 atccacccaa tcgctatcga aaacggtact aaattctcaa tccgtgaagg cggacgtaca
    29881 gttggtgccg gtgtcgttac agaaatcaaa gcttaattca cttaagtttt aaagtaaagc
    29941 aacatttatt cggacgtaat cgctcggaac gaaggtctta ggatctttgt tccgagcttt
    30001 tttatttatt gcaggatcag gaaaaaagac aggagtatta taaatagaag aaacacgaaa
    30061 taaaagagtc agtattttct aaatgaaact ttatgaaaac aaaatgtttt ttacaagaaa
    30121 aagccttgct ttgtgagttt atatatatta taatgacaaa ggtgcgttta ctttagtgaa
    30181 ttgcacagac gtaatcagaa tgatttcgtc ggctaagaaa cgagaggttg cgacacgccc
    30241 ggacgctttg ccacgaacga gcgtgacgga aattttcgtg gagctatgtc tacttttcaa
    30301 aataggcgaa ggagggaaca agatggcaaa acaaaaaatt cgtatccgtt taaaagcgta
    30361 tgaacaccgt attttagatc aatcagcgga taaaatcgtg gaaactgcaa aaagaactgg
    30421 agctagcgtg tctggtccaa ttccattacc aactgaacgc agtctttaca caatcatccg
    30481 tgcgactcat aaatacaaag attcacgcga acaattcgaa atgcgtacac acaaacgtct
    30541 tatcgacatt gtgaacccaa caccaaaaac tgttgatgct ttgatgaagc tagacttacc
    30601 atctggtgta aacatcgaaa tcaaattata aaactaaaac aaaaataatg gaggtgtact
    30661 catgaccaaa ggaatcttag ggaaaaaagt gggaatgaca caaatcttca ctgaatctgg
    30721 tgaattaatt ccagtaactg ttgtagaagc tactccaaac gtagtactac aagtgaaaac
    30781 aatggaaacg gatggctacg aagctattca agttggttac caagatatgc gtgaagtttt
    30841 atcaaacaaa cctgcgaaag gtcatgttgc aaaagcaaac acggctccta agcgcttcat
    30901 tcgtgaattc aaaaatgttg agctaggaga atatgaagta ggaaaagaaa ttacagtaga
    30961 tgttttccaa gcaggagaca ttattgatgt aacaggtact acgaaaggta aaggattcca
    31021 aggggttatc aaacgccacg gacaaagccg cggaccaatg gctcacggtt ctcgttacca
    31081 tcgtcgtcct gggtcaatgg gtccagttgc acctaaccgt gtatttaaaa acaaacgtct
    31141 tgctggccgt atgggtggca accgcgtaac tatccaaaac ttggaagttg tacgtgtcga
    31201 tgcagaaaga aatgttatct tgatcaaagg taatgttcct ggagctaaaa aatctttaat
    31261 tactatcaaa tcagctgtga aagctaaata attgtaggaa gaaaggagga actaaggaat
    31321 gccgaatgta gcattattca aacaagatgg aagccaaaac ggtgaaatca cacttaacga
    31381 agaaatcttc ggaattgaac ctaatgaaag tgttgtttac gatgcaatcg taatgcaacg
    31441 tgcgtcatta agacaaggaa cacacgcggt taaaaaccgt agcgctgttc gcggcggcgg
    31501 acgtaaacca tggcgtcaaa aaggaacagg tcgtgcacgt caaggatcta tccgctcacc
    31561 acaatggcgt ggaggtggcg tagtctttgg accaacacca cgttcttaca gctacaaact
    31621 tcctaaaaaa gttcgtcgtt tagcaatgaa atctgtattg tcagaaaaag ttgctgaaaa
    31681 caacttggta gcaatcgaag gcttgaactt cgacgcacca aaaacaaaag aattcaaaca
    31741 agttcttgct aacttatcta tcgactctaa agtattggtt gttctagaaa aaggtaacga
    31801 ctttgctgct ttatcagcac gtaacttacc aaacgtttct gtagtaactt ctgataatgt
    31861 gagtgtgcta gacgttgtat caaatacaaa agtgttagca acacaaactg ctcttactca
    31921 aattgaggag gtgcttgcat aatgaactta ctagacgtaa tcaaacgccc agtgatcact
    31981 gaaaaatcaa tgcttgccat ggatgacaag aaatacactt ttgaagtgga cactcgcgca
    32041 aacaaaactt tagtaaaaca agcggtagaa gctgcttttg acgttaaagt caaaaacgtg
    32101 aacatcgtga acgtacgtgc gaaattcaaa cgtatgggca aatatgcagg atatacaaaa
    32161 aaacgtcgca aagcgatcgt tacattgact gaagattcaa aagaaatcca attattcgaa
    32221 gctgctgaat aagcactaat agataactca ttaaattagg agggaaaaac gtggcgatta
    32281 aaaagtacaa acctacctca aatggtcgtc gtaacatgac aggttctgat tttgctgaaa
    32341 tcacaacatc aacacctgaa aaatcattgt tacaaccatt gaaaaaccat gctggacgta
    32401 acaacaacgg ccgcatcact gtacgtcatc aaggtggcgg acacaaacgc caatatcgcg
    32461 tgatcgactt caaacgtaac aaagataacg ttgttgcaac tgttcaaacg atcgaatatg
    32521 atccaaaccg ttcagctaac atcgcgttag tacactatga agatggagtg aaagcttaca
    32581 tcttagcacc taaaggacta gaagtgggta tgaaacttgt ttcaggtcca gaagcagata
    32641 tcaaagtcgg aaatgctctt ccattagaaa acattccagt tggtactgtt atccacaaca
    32701 ttgaaatgaa acctggtaaa ggtggacaat tgatccgttc tgctggtaca agtgctcaag
    32761 tacttggtaa agaaggcaaa tacgtattga tccgcttgaa ctctggtgaa gttcgtatga
    32821 tcttagctgc atgccgtgct acaatcggtt ctgtaggtaa cgaacaacac gaattaatca
    32881 acatcggtaa agctggacgc tctcgttgga tgcgtaaacg cccaactgta cgtggtagcg
    32941 taatgaaccc taatgatcac ccacacggtg gtggtgaagg taaagctcct atcggacgta
    33001 aagcaccagt ttctccttgg ggtcaaccag ctcttggtta caaaactcgt aacaaaaaag
    33061 ctaaatcaga caaacttatt gttcgtcgtc gcaaaaataa ataattactt tgaccatgtg
    33121 tcgcacattt tgagaggagg ttcaccatgg gtcgtagttt aaagaaagga ccttttgtcg
    33181 atgagcattt aatgaaaaaa gttgaagctc aagcaggggt tgaaaagaaa aaagttatca
    33241 aaacttggtc acgccgttca acagttttcc caagttttgt tggatatacc atcgcagttt
    33301 atgatggacg taaacatgta ccagtttaca tccaagaaga catggtagga cacaaattag
    33361 gtgaatttgc acctacaaga acttatcgtg gacatgctgc tgacgataag aaaacgaaac
    33421 gctaatttga ggggaggata aatccaaatg gcagaacaaa tcacatcagc taaagcaact
    33481 gcaaaaacag ttcgcacttc acctcgaaaa gcccgtttag taattgacct tatcagaggt
    33541 aaaagtgtcg cagatgcaat ttcaatcttg aaattcacac caaacaaatc tgctggaatc
    33601 attgaaaaag tattgatgtc agcagttgcg aatgcagaaa ataactttga cttagatgtt
    33661 gaaaacttgg tagtaagcga agcttttgtt aacgaaggac ctacaatgaa acgtttccgt
    33721 cctcgtgcaa aaggatcagc ttctccaatc aacaaacgta caagtcatat cacggtagtc
    33781 gtatcagaaa aataaggagg gataatcagt gggtcaaaaa gtacatccaa ttggaatgcg
    33841 tgtaggcatc atccgcgact gggatgctaa atggtatgct gaaaaagagt atgctgagtt
    33901 cttacacgaa gatttaagaa tccgtaaatt tatttcaact aaacttgctg atgctgctgt
    33961 atcaacagtt gaaatcgaac gcgcaacagg tcgcgtaaac atttcaattc acacagctaa
    34021 accaggtatg gttattggta aaggcggttc tgaagtcgaa agcctaagaa aagaattaaa
    34081 caaattaact ggtaaaagaa tccatatcaa tatcgtggaa atcaaaaaac cagatctaga
    34141 tgcaaaatta gtaggtgaag gaatcgcacg tcaattagaa aaccgtgttg ctttccgtcg
    34201 cgctcaaaaa caagccatcc aacgctcaat gcgtgctggc gctcaaggga tcaaaactca
    34261 agtatctggt cgtctaaacg gagcagatat cgctcgttca gaaggatact cagaaggaac
    34321 tgttcctctt catactttac gtgcggacat tgattacgca tgggaagaag cagatacaac
    34381 atacggaaaa ctaggagtta aagtgtggat ctatcgtgga gaaattcttc caactaaaaa
    34441 aaacactgag aaaggaggga aataatcatg ttagtaccta aacgtgtaaa acaccgtcgt
    34501 gaattccgcg gaaaaatgcg cggggaagct aaaggcggaa aagaagtagc attcggtgaa
    34561 tacggtttgc aagctgttga ttcacattgg atcacaaacc gccaaatcga agctgctcgt
    34621 atcgcaatga ctcgttacat gaaacgtggt gggaaagtat ggattaaaat tttccctcac
    34681 aaatcttata ctgccaaagc aattggggta cgtatgggtt ctggtaaagg ggcacctgaa
    34741 ggatgggttg caccagtaaa acgtggtaaa atcatgtttg aaatcgcagg cgttcctgaa
    34801 gaagtagctc gtgaagcgtt acgtctagct tctcacaaat taccaatgaa aactaagatc
    34861 gtaaaacgtg aggaaatggg tggtgaatcg aatgaaggtt aaagaaatca gagaattaac
    34921 cactgccgaa atgcttgatc aagaaaaaca attaaaagaa gaattgttta atcttagatt
    34981 ccaattagca acaggtcaat tagaaaacac tgcacgtatt aaagaagtac gtaaatcgat
    35041 tgcacgcatc aaaactgtgt tgcgtgaaca agctaagtaa ttatggaagg aggccattaa
    35101 gcgtatgact gaaggaagaa atcaacgcaa agtttatcaa ggtcgcgtgg tttcagacaa
    35161 aatggataaa acaattaccg ttgctgtcga aacaaagaaa aaccacccta tctatggcaa
    35221 acgcatgaac tattctaaga aatacaaagt gcatgatgaa aacaacacag caaaagttgg
    35281 cgacatcgtg agaattatgg aaactcgtcc attatcagct acaaaacgtt tccgtttgtt
    35341 ggaagtagtc gaagaagcag ttattatcta ataacacgag attttcctat atagattgaa
    35401 tgcaaaatct gaaaggagga tacacaacgt gatccaagca gaaagtcgtt taaaagtcgc
    35461 tgataactca ggcgcacgtg aaattttgac gatcaaagtc cttggtggat ctggtcgtaa
    35521 aactgctaac atcggtgatg tgatcgttgc tacggttaaa caagcaacgc caggtggggt
    35581 tgtcaaaaaa ggtgacgtcg ttaaagccgt tatcgttcga acaaaatcag gagctcgtcg
    35641 tacagacggt tcatatatta aatttgatga aaatgctgca gtgattattc gtgatgataa
    35701 aagccctcgt ggaacacgta tctttgggcc agttgcacgt gaactacgtg aaaacaactt
    35761 catgaagatc gtttcactag caccagaagt tttataatct tgagacactt atcaaaggag
    35821 gtgcgaaaca gttatgtttg ttaaaaaagg cgataaagtt aaagttatca ctggaaaaga
    35881 caaaaacaaa gaaggcgttg tactagcagc gttcccgaaa aaagataaag ttattgtcga
    35941 aggtgtaaat gtcgttaaaa aacaccaaaa accttctcaa gctgctcctc aaggtggaat
    36001 tgttgagatg gaagcgccaa ttcatgtttc taacgtgatg gtggttgact ctactggtgt
    36061 agctggccga gttggctaca aagaagtaga cggcaaaaaa gtccgtgttt ctaaaaaaac
    36121 cggtgaagtt ttagataaat aaaagtttaa ggaaggaggg tcttactgaa tgaaccgcct
    36181 aaaagaaaaa tatcttaaag aagtaactcc atcattgatg gaaaaattta actatagctc
    36241 tgttatgcaa acacctaaag ttgaaaaaat cgtcatcaac atgggtgttg gtgatgcggt
    36301 atcaaacgct aaaaacttag ataaagcagt tgaagaatta actttgatca ctggtcaaaa
    36361 accaatgatt acaaaagcta aaaaatcaat cgctggattc cgtttacgtg aaggaatgcc
    36421 aattggtgca aaagttacat tgcgcggaga aagaatgtac gaattcttag acaaattggt
    36481 ttctgtttca ctaccacgtg tacgtgactt ccatggtgta agtaaaaaag cctttgacgg
    36541 tcgtggaaac tatactttag gtattaaaga acaattgatc ttcccagaag tagattatga
    36601 tttagtagat aaagtacgtg gtatggacat cgttattgta acaacagcaa actctgatga
    36661 agaatctcgt gagttgttga cacaattagg catgccattc caaaaataat taaaggaggc
    36721 gaactacgtg gctaaaaaat caatgattgc taaaaacaaa cgtcctgcaa aattttcaac
    36781 acaagcttat actcgttgcg aacgttgcgg acgtccacat tcagtttatc gtaagttcca
    36841 tctttgccgt atttgcttcc gcgaacttgc ctataaaggt caaattcccg gcgtgaagaa
    36901 agctagctgg taaaaagtaa attcgcataa gaaggaggta aaagatcaat ggtcatgaca
    36961 gatccaattg cagattttct aactcgtatc cgtaacgcaa acatggttaa acatgagtct
    37021 ttagaagtac ctgcatcaaa aattaaacgt gacatcgctg aaatcttgaa acgtgaaggt
    37081 ttcgttcgtg atgttgaata catcgaagat gacaaacaag gcgtgatccg tgttttccta
    37141 aaatttggta aaaacggcga acgtgttatc acaaacttaa aacgtatctc taaaccaggt
    37201 ttgcgtgctt atgtcaaagc tgacgaagta ccaaaagtat tgaacggttt aggtatcgca
    37261 atcatttcga cttctgaagg tgttgtcact gataaagaag ctcgtgaaaa aaatatcggc
    37321 ggcgaagtta tcgcttacgt atggtaatca agtagaatct acaaggaggt gtctttaagt
    37381 gagccgtatc ggaaataaag tcgttgttat ccctgaagga gtaacagtta ctcaagacgg
    37441 aaacaacgtt acagttaaag gaccaaaagg tgaattgact cgtacttttt cagcagatat
    37501 caaaatgaat atcgaaggaa acgaagtaac tttcactcgt ccaaacgaca gtaaagaaat
    37561 gaaaacaatt catggaacaa ctcgtgcgaa cttcaacaac atggttgtag gtgtcagcga
    37621 aggtttccaa aaagcgttag aactaatcgg ggttgggtac cgtgcacaat tacaaggatc
    37681 aaaacttgta ttgaacgttg gttactcaca tccagtagaa atcacaccac cagctggagt
    37741 aactgttgaa gtaccagcta acacacaagt aattgttaaa ggtgcgaaca aagaagaagt
    37801 tggcgaatta gctgcaaaca ttcgtggaac tcgtcctcca gaaccttata aaggtaaagg
    37861 tattcgttat gttggcgaat atgtacgccg taaagaaggt aaaactggta aataatcgtt
    37921 tagaaaaatt gcatagaagc cagcagcagg aaaaaggcat ttggctgaag tttaccttca
    37981 aaaaaataca tttttacttg tgccgcagct tctatttttc gaaacgtatt tactgcttga
    38041 aatagtagta caataaaaat aaagaggtga caattgtgat tacaaaacca gataagaaca
    38101 aaacacgtca aaagagacat cgtcgtgtac gtaacaatat ctctggtact gctgagcgcc
    38161 cacgcttgaa cgtttttcgt tctaacaaaa acatctacgc tcaaattatt gatgacgtag
    38221 cgggtgtaac gctagcaagt gcctctacct tggataaaga aatttcaggt ggaacaaaaa
    38281 cagaagcagc acaagctgtc ggtaaactag ttgctgaacg tgcagctgaa aaaggcatta
    38341 aagtagtagt ctttgaccgt ggtggatacc tttaccatgg ccgtgtgcaa gctttagctg
    38401 aagctgctcg cgaaaatgga ctagaatttt agaagaagga ggaataccat tcatggttta
    38461 tatcgatcca aaacatttgg aattagaaga ccgcgttgtt gcaattaacc gtgtaacaaa
    38521 agttgttaaa ggtggacgtc gtctacgttt tgctgcttta gttgttgtcg gtgacaaaaa
    38581 cggacacgta gggtttggta caggtaaagc tcaagaagtt cctgaagcaa tccgtaaagc
    38641 aattgaagat gcgaagaaaa acttagttga agtacctatg gttggttcaa caatcccaca
    38701 cgaagtaatc ggtgctttta gtggtggtag aatcctaatg aaacctgctg tagaaggttc
    38761 tggggttgct gctggtggac cagttcgtgc cgtattagaa ttagctgggg tagcagatat
    38821 cacttctaaa tctttaggct caaatacacc aatcaacgtt gttcgcgcaa cagttgaagg
    38881 tttgaaacaa ttgaaacgtg cagaagaagt tgcagaactt cgcggcaaat cagttgaaga
    38941 attaatcgga taaggaggac aacaataatg gctgaattaa aagttacttt aaaacgcagt
    39001 attatcggac gtcctcaaaa ccaacgcgat acagttaaag cgttaggtct tacaaagatt
    39061 aacagttcag tggttaagcc ttctaatgaa gcaattaaag gcatgatcaa tactgtttct
    39121 cacctagtgg acgttgaaga aatttaattt agaaaaatca taactagaac attaaggagg
    39181 tgccaaacct atgaaacttc atgaattaaa acctgctgaa ggttcacgcc aagtacgtaa
    39241 ccgtgttggt cgtggtactt catctggtaa cggaaaaact gccggacgcg gacaaaaagg
    39301 acaaaaagct cgttcaggcg gcggtgtgcg tttaggattt gaagggggac aaacaccatt
    39361 gttccgtcgt ttaccaaaac gaggattcac aaacgtgaac cgtaaagact atgcagtcat
    39421 taatcttgat gtattgaacc gctttgaaga cggagctgaa gtaactcctg ttgctttagt
    39481 tgaagctgga atcgtgaaaa acgaaaaagc tggaatcaaa gtattagcta atggggaact
    39541 aaacaagaaa ttaactgtga aagcagcaaa attctctaaa gcagctcaag aagcaattga
    39601 agcggctggt ggatcaatcg aggtgatcta atgtttagac tattaaaaga tgcttttaaa
    39661 gtaaaagaca ttagatcgaa aatcctattt actgtatttg tgttgtttgt atttcgccta
    39721 ggtgcacata ttactgtacc aggcgtaaat gctgcttcat tgcaaaacct ttcttctttg
    39781 ccatttttca acatgttgaa cttggtaagt ggtagtgcga tgcaaaactt ttccattttc
    39841 tcaatggggg tttcaccata cattactgct tctatcgtca ttcagcttct tcaaatggac
    39901 atcgtgcctc gatttgttga atggtcgaaa caaggggaag ttggtcgtaa aaaactgaat
    39961 caagcgactc gatatctgac attagtattg gcatttatcc aatctgtcgg tatcactgct
    40021 ggattcaatc aatacgctca attaggtttc gtgaataatc ctaacgtagc aacttacgta
    40081 acgatcggtt tgattctaac agccggtacg atgtttgtta cttggctagg agaacagatc
    40141 acagaaaaag gtatcggaaa tggcgtatca atgatcattt ttgcaggtat catttctaga
    40201 ttgcctgaaa gtatcagaga aatttatgaa gattacttta taaatattga tccttcagac
    40261 atatggaaat ctgctatttt tgtggccatt ttactagtag cggtcttgtt gatcgtgaca
    40321 ttcgtaacat ttttccaaca agctgaacgc aagatcccga tccaatatac gaaacgcgta
    40381 gctggcgcgc ctacaagcag ctatctgccg ttgaaagtaa atgcagctgg agttattcca
    40441 gttatctttg ctagttcgtt tattgctacg ccaaatgctg ttttacaagc attgagcggt
    40501 agattcggtt ctgaaaactg gtacaaagtg atgatggaga tctttaacta taatacagca
    40561 cctggtgcta cgatttatac gattctgatc gttgccttca ctttcttcta cgcctttgtt
    40621 caagtaaacc ctgagaaatt agcggaaaac ttgcaaaagc aaggaagtta tataccaagc
    40681 gtacgccctg gtaaggggac tgaagagtat gtctcaagat tactgatgcg tttaagtaca
    40741 gttggtgcag tcttccttgg tttagtggca ttgcttccaa tcattgctca aatggtttgg
    40801 gatcttccac aatcaatcgg attaggcggt acaagcttac tgatcgttat cggtgtagct
    40861 ttagaaactg cgaaacagtt agaaggctta atgctgaaac gtaaatatgt tggattcatt
    40921 gagtaagaaa gcgtgttgag gtttcccctc aacacacgtt ctcacacatt tattaggagg
    40981 gaaaacaatg aacctcattt taatggggct gccaggcgca ggtaaaggaa cacaagctga
    41041 aaaaatcatt gatgcttatg gtattccgca catctcaaca ggagatatgt tccgcgcagc
    41101 gatgcaaaac gaaacagctc ttggcctgga agcaaagtct tatatggata aaggtgcatt
    41161 agttcctgat gaagtaacaa atggaatcgt gaaagagcga ctagctgaac cagatacaga
    41221 gaaaggcttc ttattagatg gctttccacg tacgctagat caagcaaaag ctctggacgc
    41281 aatgctaaaa gatttgaata aaaaaattga tgctgtcatc gatatccatg ttggtgaaga
    41341 aatcttggtc gaacgtctag ccggccgatt tatctgcagc aattgtggag caacttacca
    41401 taaaattttc aaccctacaa aagttgaaga cacatgtgat cgttgcggtg ggcatgaatt
    41461 ctatcaaaga gaagatgata aacctgagac ggttaaaaat cgtctggcta tcaacatcaa
    41521 aaatagtgaa ccaatcttgg cttattataa agaacaaggt ttgctaaaca ctattgatgg
    41581 tgctcgtgaa atcgatgctg tatttgcaga tgtacaaaaa atcattgaaa aatagcacga
    41641 ttgcccgtag ccgacttgca ttatgcagtt actcttgtca agttcaataa attatgatag
    41701 aatatgtcag tccgacttct agagaatcct ctagatgatc cattttgaga attttgaggt
    41761 gggaactgca gtttccgcca ttttatcgtg tgaaaatgcg aaacaagtac aaggaggtac
    41821 tgtgcgtggc aaaagaagat atgattgaag tcgaaggtac agtcgtcgaa actttgccga
    41881 atgcaatgtt taaagttgaa ctagaaaacg gacaccaagt tcttgctact gtttcaggta
    41941 aaattcgtat gcattacatc cgtatcttac ctggtgacaa agtaacggtt gaattgtctc
    42001 catacgatct taaccgtggc cgtattactt atcgctttaa ataattgtac tccgtaaaac
    42061 tacaggaggt attatcatga aagtaagacc atcagtaaaa ccaatgtgcg aacattgtaa
    42121 agtaattcgt cgtaaaggac gcgttatggt gatttgccca gcaaatccaa aacataaaca
    42181 acgtcaagga taattggagg tgctataaat atggctcgta ttgcaggagt agatattcct
    42241 cgtgataaac gtgtagtagt ttcacttact tatatctatg gtattggtaa cactactgct
    42301 aaaaagatct tagctgatgc tggtgtatct gaagatgttc gcgttcgtga attaacgaat
    42361 gaacaaacag atgctatccg tgcagaagta gataaattaa aagttgaagg ggatcttcgt
    42421 cgtgaagtga acttgaacat caaacgtttg atggaaatcg gttcttaccg tggaatccgt
    42481 catcgccgtg gattgcctgt tcgtggacaa aacacgaaaa acaatgcacg tactcgtaaa
    42541 ggcccagctc gcgctatcgc tggcaagaaa aaataattct taagtgaagg aggttaaaac
    42601 ttcatggcag caaaaaaagt gaatcgtaaa cgccgtgtga agaagaatat agaagcaggt
    42661 attgcacata tccattctac attcaataac actatcatca tgatcactga tactcacgga
    42721 aatgcattag cgtggtcatc agctggttca ttaggtttca aaggaagcaa aaaatcaact
    42781 ccttttgccg ctcaaatggc agcagaaact gctacaaaag cagcaatgga acacggatta
    42841 aagactgttg aagtaacagt taaaggacct ggttctggac gtgaagcagc aattcgttca
    42901 ttacaagcta caggtttaga agtgactgca attcgtgacg tgactccagt tcctcataat
    42961 ggtgcccgcc ctccaaaacg ccgtcgtgtt taatgagtgc cgctcatttt gagttttatc
    43021 agtaacgtca ttgaacaaga cacttttcgt tttgaaaggg gtaaagataa gaatgattga
    43081 gttcgaaaaa ccaagaatcg caaaaattga tgaagaaaaa gattatggca agttcatcgt
    43141 tgaacctctt gaaagagggt atgggactac tttagggaat tccctacgtc gtattttatt
    43201 atcttctttg ccaggtgctg ccatcactaa tattcaaatc gatggtgtac tgcatgaatt
    43261 ctctaccatc aaaggtgtta gagaagacgt cactcaaatc atcttgaaca ttaaaggctt
    43321 agcgctgaaa atgtatggcc aagaagaaaa aacccttgaa atcgatatta ccggacctgc
    43381 tacagtaact gctggcgata ttatcgttga tagtgatgta gaaattctta acaaagatat
    43441 gtacatctgt agtgtctctg aaggagctac gttccatgct cgcttaacag tgaaacctgg
    43501 acgtggttat gttcaagcag atgaaaataa aaaagaagat atgccaattg gcgttcttcc
    43561 agtcgattca atctacacac ctgttcgtcg tgtgaactat caagttgaga acacacgtgt
    43621 tggacaccgt gaagattttg ataaattgac gatggagatt tggacagatg gttcaattga
    43681 accgttggaa gcaatgagtt tgtctgcgaa aatcatgact gaacatttgg atatttttgt
    43741 gaacttaact gatgaagcaa aaaatgctga aatcatggtc gaaaaagaag aaacacaaaa
    43801 agaaaaaatg ttggaaatga cgatcgaaga gttagacttg tctgttcgct cttacaattg
    43861 tttgaaacgt gcaggaatca atactgtaca agaacttaca aataaatctg agcctgaaat
    43921 gatcaaagtc cgtaacttag gacgtaaatc attagaagaa gttaaagcaa aattgcacga
    43981 cttaggttta ggtttacgta aagaagatta aaacctttta cgaaggaggg aaaccaacgt
    44041 gagttatcgt aaactaggac gcacatctag ccaacgtaaa gcgatgttgc gtgatttaac
    44101 aactgattta ttaatcaacg aacgtattgt gactactgaa gctcgtgcga aagaagttcg
    44161 ctcaactgca gaaaaaatga tcactttagg taaacgcgga gatttgcatg cacgtcgtca
    44221 agctgcggct ttcgtacgta atgaagttgc cagcgtgcgt gaagaaaatg aggacatcgt
    44281 cattgaatca gctttacaaa aactgttcaa cgatattgca cctcgttacg cagaacgtca
    44341 aggcggatac acacgcattt tgaagacaga accaagacgc ggtgatggtg caccaatggt
    44401 tgtcttagaa cttgtctaaa atcacactaa taacatcact ttatagatga ttcttttaga
    44461 gtgttatgat gttggaagat atttttccga gtctagctca gcgctgctcc tcaagcgaat
    44521 atcgcttggg gagtaagcac tcatcataaa gtgttttttt ataccttcaa ttacctgtca
    44581 tgacagatat gtttgaaggc ataaaaaaac attttaagcg agaaataatt gaaaattttg
    44641 tctttttttg atagtgttag taggaacttt aggatgaaga aggagtaatc atggagccaa
    44701 ttattgaatt agaaaagata aattataaat accagccaga tgatcttcgc cccgcattga
    44761 aagatgtctc ctttacaatt gataaaggtg agtggatcgc tattattgga cacaatggtt
    44821 caggaaaatc gacacttgcc aaaacgatca atggattgct tctgccagaa tcagggatcg
    44881 tgaaagtggg aaatcaaata ttggatgaag aaaatatttg gacgatccga cagatggttg
    44941 gaatggtttt tcaaaatcca gacaatcagt ttgttggttc gacagtagaa gatgacgttg
    45001 cttttggtct tgaaaatcaa gggattccca gagaagaaat gctagtgcgt gtgaaagatg
    45061 cacttgagaa agttagaatg gctgagtttg cttcacgcga gcctgctcgt ttatcaggag
    45121 ggcaaaaaca acgtgttgcc attgccggcg tggttgcctt acgacctgat atcattattt
    45181 tagatgaagc aaccagtatg ctagatccag aaggtcgtga agaagtgatc tctacgatca
    45241 agaagatcaa agaagaaagt caattgaccg ttatatctat cactcatgat attgatgaag
    45301 cagctaatgc caatcggata ctagtgatga gacaaggcga acttgtccgt gaaggtacac
    45361 caaaagaaat tttttctgct ggtcctgaac tgatcgactt aggtctagat ctaccatttc
    45421 ctgaaaaact gaagagcgca ctgaaagaac gtggggttga tgtgcccagt gaatatatga
    45481 cagaagaaag gatggtggat tggttatgga catccgtttt gaacaagtag acttcactta
    45541 tcagccgaat acaccatttg aacaaagagc cttatttgac atcaatatga cgatcaaaga
    45601 aaacagttat actgcattag tagggcatac cggaagcggg aaatcaacct tacttcagca
    45661 tttgaatgcg cttgttaagc caacaagcgg tacagtccat attggagaac gagatattca
    45721 gccggatacg gataataaga atttaaagcc catccgaaaa aaagttggca tcgtctttca
    45781 gtttccagaa gcacagctat tcgaagaaac ggtagcaaaa gacattgctt tcggtcctaa
    45841 aaactttggt gtcagcgaag aagaagcact agtcctagca aaagaaacat tagaacaagt
    45901 tgggctggat gaaagctatt tggaacgttc gccatttgaa ctttcaggag ggcaaatgcg
    45961 tagagtagca atcgctggtg tgcttgccat gaggccggaa gtacttgtat tggatgaacc
    46021 aacggcagga cttgatcccc agggtagaaa agaaatgatg gagatgtttt ggcgtcttca
    46081 taaggaacag cagatcacta ttgtattagt tacgcattta atggatgatg tagccaattt
    46141 tgcagattat gtctatgtgt tggaaaaggg acgaatcgtt aatagcgggg agccgcaaga
    46201 ggtctttcaa aacattgaat ggctaaaaga aaaacaacta ggcgtaccta ctgccaccga
    46261 gtttgcagaa gaattaatgg ctaaagggat gaactttgct accttgcctt tgacagctga
    46321 agaattagca gacgctatcg tccattatgc tggaggaaat gcccatgatg aataaattga
    46381 tatttggtcg ttatatgcct ggagattcct tgatccatcg attggatccc cgagctaaat
    46441 tattagccag tttttatttt atcggaatca tttttttagc aaataattgg gaaacgtacc
    46501 ttttgttggc atttttcaca ttactttctg tcttcttgtc aaaagtagat ttgaaatttt
    46561 ttatccgagg cattcgccca ttgatctggc taatcctctt cactgtagct ttgcaggtct
    46621 tgtttacaag tggcggagaa acttattgga gttggggtgt tttccatatc actgaatttg
    46681 gtgtgatgaa cggcctcttt attttctgtc gattcgtgtt gatcattttt atgtcgactc
    46741 tactcacgct tactacaccg cctttggaat tatcggatgc gattgagtac ttgcttcgtc
    46801 cattgaaagc cgtacggttc ccagtccacg aaatttcatt gatgctgtcg attgctcttc
    46861 gttttgtgcc tacattgatg gacgaaacag aaaagatcat gaacgctcag cgcgctcgcg
    46921 gtgttgattt tggtgaagga aacctagttc agaaaatgaa agcagtcatt cctttgctga
    46981 ttcctttatt tgtcagcagc ttcaaccgtg cggaagatct tgcgactgct atggaagcaa
    47041 gaggctacaa aggtggggaa ggaagaacga aatatcgtgt attgcattgg cataatagag
    47101 acacgatggt tatcattgct tttgtattat taactgtgct actgatcttt ttgagaggat
    47161 aaacgttcag tgggccgcta tctattcttt tcttgctgat ctgtttgcaa gaaaggatgc
    47221 gagcagtgta tgacaagaaa tattagggtc tgtggcagac taaggtcaca ggcctctttc
    47281 ttttatctga aaagaaagaa cgaaaaaatt ttataaaaaa atcattattc cagataacct
    47341 tttaggaaca aaggagagaa aaacatggta cgttacaaag caatcattgc atacgacgga
    47401 acaaatttta atggattcca aaaacagcca aatgggcgta ctgttcaaga agaagtagaa
    47461 aaaacattac aaaaaatggc aaatggaaaa gaaatcacgg tctttggttc gggaaggaca
    47521 gatgccggag tacatgcgat tgggcaagta atccattttg attatccaga ggagcgtccg
    47581 ttagaacgaa tgcgtttcgc gctagatacc cagtcaccag aggatattgc tgtaagacaa
    47641 gtagaaattg tttcagaaga cttccacgca agatatttgg tcaaagaaaa gacgtatcaa
    47701 tttcgagtgg atatagggaa accacgcagt ccttttcgac gccattatgc aagttatttt
    47761 ccttaccctc ttgatttgga aaaaattcag cgggcgcttc ctgatttatt agggactcac
    47821 gatttcacct ctttttgtgc atcaggaagc tcgatagagg ataaagtacg tacgatctac
    47881 gaggctaaga tggaggtaaa tgaaacaaaa gacgaattgt tgtttacatt taggggaaat
    47941 ggcttcttgt ataagatgat acggatctta gtaggaacgc ttttgaaaat tggcaatggc
    48001 cgattgcctg aagatagtat cccagatatt attgcgaaaa aagatcgtaa tgcagcagga
    48061 cctacagcac atcctgaagg actttatttg tatgaagtga aatatgaata agaggttgtg
    48121 acagaagtgg tcagcttcaa gaaataagaa ggaatttacg aaaattactt ctcaaaattt
    48181 tgcaaaattt cggcttattt tcgaaggagc tacttctgga acaccgtgaa tcagaggttg
    48241 tgaaaaagct gccctgcatc aagtaataag aacaaccaaa caaaaatagc tcgtcatatt
    48301 tttcgtttgg ttgggcttat taccgcagat gcaagctttt gaacaccgtt taaggaagag
    48361 gttgtgaaat cagcgttttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    48421 tattttgccg tttgttgagc taataccgaa ggtcagctga ttgaacaccg tttaagaaag
    48481 aggtcgtgag cctgtcattt aactctgagt cacaagtaac aatttcaaaa aacagcttct
    48541 catctttgat gaatatcgtg acttgtggac gaggcgttga taagtgaatc atctttttgt
    48601 tacctatttt ttctgtaacc aaaaaacgat ggaacgttgt tttgattgcc cttaatgagg
    48661 acagtcggaa caggtttgtc atttttatat ttaaatggca caaatttttc taattatttg
    48721 tcatttagcg ctgaaaattt ttgctattta tctaaaaaag tgataactac ttaagatgaa
    48781 gcagaatatt tacgccatac ggcatacaac cgcgaaaaat ataaaaaaaa gaaaacgatt
    48841 gaacgcgttt ttgcagtcgc aaaggaaaag catggaatgc gctacatcaa gtatcgagac
    48901 ttggaaaaca atcaggtgta tacgctgatt gtttttgctg caatgaatct gaaaaagttg
    48961 tccacttggc agttggaaca tatgtcttca tatcttttat tatacaaaaa tagcaaaagc
    49021 accagtctac actcttagta aagaggaaac tgatcctttt gtctacattc ttaaagtact
    49081 taaactaagt actttatttt actctttagg attgatacag tagcatctat ccctttatta
    49141 ataatctttt atttttttaa ataaagatgt tgtctccatc ttcaggcact aaaacttttt
    49201 cggaaattcc tttttcttta ttgaaagact ttaattcttc tcttgacagt ccccaatggt
    49261 ttacagcttc catatgaacg gcaataattg tggaatctgg tattgcttta tgcaattcat
    49321 ataaatcgtc tttccccata ataagagatt ctccaactaa aaaatgatta tctccagcat
    49381 ttgctactat gatttctgga ttatactgat caatagtttg tttaacagct tcataccaaa
    49441 ctgtatctcc tgtaaagtat agtgtcttct cagtcgaatg tttgaaaaca ataccgcaaa
    49501 cattacctac ataattcaag atttctcctc tgccatgttt gccttttgtt ttaaccaatt
    49561 gtatagattc aaaaactgtg tcttctcgta gtacctccac atttttaaaa ccatatagtc
    49621 gaatttcatt cgcatcattt tcatcttgca caaataattt tatttcttta ggtaggacct
    49681 ctttcgctat atcgtcccaa tgatctagat gtaaatgtgt tacaataaca gcatcaatac
    49741 cgttgataat atcttcgact ggcattggca aatcaactag aggattcatt tgatcttttc
    49801 ttggtgatgg aaaaggacct ttcgaaataa atggtggaag tgttcctttt tccgctaaca
    49861 ttggatcaat taaaaatttt ttacctccat agtctaagat agctgttgca ttacgaatgt
    49921 gatgtatatt cataaacgtt gtctcctttt tgttgatatg aaatattttt agtata
//
LOCUS       DADVXV010000012        46944 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.012, whole genome shotgun sequence.
ACCESSION   DADVXV010000012 DADVXV010000000
VERSION     DADVXV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 46944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.012"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            51..1196
                     /gene="tgt"
                     /locus_tag="KB969_000630"
     CDS             51..1196
                     /gene="tgt"
                     /locus_tag="KB969_000630"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBB6868643.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            1293..1673
                     /gene="yajC"
                     /locus_tag="KB969_000631"
     CDS             1293..1673
                     /gene="yajC"
                     /locus_tag="KB969_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBB6868644.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            1978..4575
                     /gene="adhE"
                     /locus_tag="KB969_000632"
                     /gene_synonym="adhC"
     CDS             1978..4575
                     /gene="adhE"
                     /locus_tag="KB969_000632"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBB6868645.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            4804..5910
                     /locus_tag="KB969_000633"
     CDS             4804..5910
                     /locus_tag="KB969_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6868646.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            5927..6955
                     /locus_tag="KB969_000634"
     CDS             5927..6955
                     /locus_tag="KB969_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBB6868647.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            6961..7440
                     /locus_tag="KB969_000635"
     CDS             6961..7440
                     /locus_tag="KB969_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBB6868648.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            7456..8751
                     /locus_tag="KB969_000636"
     CDS             7456..8751
                     /locus_tag="KB969_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBB6868649.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            8762..9586
                     /locus_tag="KB969_000637"
     CDS             8762..9586
                     /locus_tag="KB969_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6868650.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            9751..10650
                     /locus_tag="KB969_000638"
     CDS             9751..10650
                     /locus_tag="KB969_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6868651.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(10776..11645)
                     /locus_tag="KB969_000639"
     CDS             complement(10776..11645)
                     /locus_tag="KB969_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBB6868652.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            11798..13258
                     /gene="rhaB"
                     /locus_tag="KB969_000640"
     CDS             11798..13258
                     /gene="rhaB"
                     /locus_tag="KB969_000640"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBB6868653.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            13255..14511
                     /gene="rhaA"
                     /locus_tag="KB969_000641"
     CDS             13255..14511
                     /gene="rhaA"
                     /locus_tag="KB969_000641"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBB6868654.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            14525..15370
                     /gene="rhaD"
                     /locus_tag="KB969_000642"
     CDS             14525..15370
                     /gene="rhaD"
                     /locus_tag="KB969_000642"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBB6868655.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            15372..15683
                     /gene="rhaM"
                     /locus_tag="KB969_000643"
     CDS             15372..15683
                     /gene="rhaM"
                     /locus_tag="KB969_000643"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBB6868656.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            15765..16916
                     /gene="fucO"
                     /locus_tag="KB969_000644"
     CDS             15765..16916
                     /gene="fucO"
                     /locus_tag="KB969_000644"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBB6868657.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            17043..17801
                     /locus_tag="KB969_000645"
     CDS             17043..17801
                     /locus_tag="KB969_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBB6868658.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            17901..18545
                     /locus_tag="KB969_000646"
     CDS             17901..18545
                     /locus_tag="KB969_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBB6868659.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            18552..19559
                     /locus_tag="KB969_000647"
     CDS             18552..19559
                     /locus_tag="KB969_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBB6868660.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            19575..20417
                     /gene="kduI"
                     /locus_tag="KB969_000648"
     CDS             19575..20417
                     /gene="kduI"
                     /locus_tag="KB969_000648"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBB6868661.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            20437..21240
                     /locus_tag="KB969_000649"
     CDS             20437..21240
                     /locus_tag="KB969_000649"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBB6868662.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(21489..22553)
                     /locus_tag="KB969_000650"
     CDS             complement(21489..22553)
                     /locus_tag="KB969_000650"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBB6868663.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(22550..23635)
                     /locus_tag="KB969_000651"
     CDS             complement(22550..23635)
                     /locus_tag="KB969_000651"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBB6868664.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(23648..24625)
                     /gene="mvaD"
                     /locus_tag="KB969_000652"
     CDS             complement(23648..24625)
                     /gene="mvaD"
                     /locus_tag="KB969_000652"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBB6868665.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(24618..25562)
                     /gene="mvk"
                     /locus_tag="KB969_000653"
     CDS             complement(24618..25562)
                     /gene="mvk"
                     /locus_tag="KB969_000653"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBB6868666.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            25878..26537
                     /locus_tag="KB969_000654"
     CDS             25878..26537
                     /locus_tag="KB969_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6868667.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            26622..27527
                     /locus_tag="KB969_000655"
     CDS             26622..27527
                     /locus_tag="KB969_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6868668.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(27529..28161)
                     /locus_tag="KB969_000656"
     CDS             complement(27529..28161)
                     /locus_tag="KB969_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6868669.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    28312..28437
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            28481..29005
                     /gene="infC"
                     /locus_tag="KB969_000657"
     CDS             28481..29005
                     /gene="infC"
                     /locus_tag="KB969_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBB6868670.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            29077..29277
                     /gene="rpmI"
                     /locus_tag="KB969_000658"
     CDS             29077..29277
                     /gene="rpmI"
                     /locus_tag="KB969_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBB6868671.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            29330..29689
                     /gene="rplT"
                     /locus_tag="KB969_000659"
     CDS             29330..29689
                     /gene="rplT"
                     /locus_tag="KB969_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBB6868672.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            29941..31278
                     /locus_tag="KB969_000660"
     CDS             29941..31278
                     /locus_tag="KB969_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBB6868673.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            31326..33455
                     /locus_tag="KB969_000661"
     CDS             31326..33455
                     /locus_tag="KB969_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBB6868674.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            33430..34119
                     /locus_tag="KB969_000662"
     CDS             33430..34119
                     /locus_tag="KB969_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868675.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(34527..35204)
                     /locus_tag="KB969_000663"
     CDS             complement(34527..35204)
                     /locus_tag="KB969_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6868676.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTRFRWLR
                     LTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDYFED
                     IQDRPIK"
     gene            complement(35340..35534)
                     /locus_tag="KB969_000664"
     CDS             complement(35340..35534)
                     /locus_tag="KB969_000664"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868677.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(35584..36024)
                     /locus_tag="KB969_000665"
     CDS             complement(35584..36024)
                     /locus_tag="KB969_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBB6868678.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(36028..36873)
                     /locus_tag="KB969_000666"
     CDS             complement(36028..36873)
                     /locus_tag="KB969_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBB6868679.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            37022..38440
                     /gene="pepV"
                     /locus_tag="KB969_000667"
     CDS             37022..38440
                     /gene="pepV"
                     /locus_tag="KB969_000667"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBB6868680.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(38497..39444)
                     /locus_tag="KB969_000668"
     CDS             complement(38497..39444)
                     /locus_tag="KB969_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6868681.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(39667..40017)
                     /locus_tag="KB969_000669"
     CDS             complement(39667..40017)
                     /locus_tag="KB969_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6868682.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            40217..41296
                     /gene="pepA"
                     /locus_tag="KB969_000670"
     CDS             40217..41296
                     /gene="pepA"
                     /locus_tag="KB969_000670"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBB6868683.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            41440..41760
                     /locus_tag="KB969_000671"
     CDS             41440..41760
                     /locus_tag="KB969_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6868684.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            41782..42246
                     /locus_tag="KB969_000672"
     CDS             41782..42246
                     /locus_tag="KB969_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6868685.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            42451..43056
                     /locus_tag="KB969_000673"
     CDS             42451..43056
                     /locus_tag="KB969_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBB6868686.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(43095..44384)
                     /locus_tag="KB969_000674"
     CDS             complement(43095..44384)
                     /locus_tag="KB969_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBB6868687.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            44812..45291
                     /gene="rlmH"
                     /locus_tag="KB969_000675"
     CDS             44812..45291
                     /gene="rlmH"
                     /locus_tag="KB969_000675"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBB6868688.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            45494..46044
                     /locus_tag="KB969_000676"
                     /pseudo
     CDS             45494..46044
                     /locus_tag="KB969_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299296.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
     gene            46115..>46944
                     /locus_tag="KB969_000677"
     CDS             46115..>46944
                     /locus_tag="KB969_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfa13 family transposase"
                     /protein_id="HBB6868689.1"
                     /translation="MNDFTTEIMEILINKGDLDDLFRRHLELAINALLQAELTVFLDY
                     EKYDRAGFNSGNSRNGNYSRSFKTEYGELNLVIPRDRNGDFSQQTLPAYKRTNDSLET
                     TIIQLVQKGITMSEISDLIEKMYGHYYKPQTISNMSKIVSEDVSAFKERTLEAKYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRG
                     LEEVLLVVTDGLSGIDDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     "
BASE COUNT        14986 a         8456 c         9996 g        13506 t
ORIGIN      
        1 tatgatggtg ggagttgtca agatatttta tatagaaagt agggaaatga atgacgcaac
       61 ctgccattcg ctatcgttta atcaagaaag aaaaacatac tggcgcgcgt ttaggggaat
      121 tgatcacgcc acacggaact ttccccacac caatgttcat gccagtagga acattagcta
      181 cagtaaaaac aatgtcccca gaagagttga aagaaatggg tgctggcgtt attttaagta
      241 atacatatca tttatggcta cgccctggtg aagacttagt agaagaagct ggcggactgc
      301 ataaatttat gaactgggat caaccgattt taacagattc aggcggcttt caagtttttt
      361 cattaagtga tatgcggaat atcgaagaag aaggcgtgca tttcaaaaat cacttgaacg
      421 gttcgcgtat gtttttatca ccagaaaaag caatcaacat ccaaaataaa ttgggctctg
      481 atatcatgat gagttttgac gaatgtccac cattcgatga aagttacgac tacgtgaaaa
      541 aatcagtaga acgtacgtct cgatgggcag aacgaggatt gaaagctcat gctaatccag
      601 accgtcaagg attatttgga atcatccaag gagcagggtt tgaagatctt cgtcgtcaaa
      661 gcgcgaaaga tctagtcggg atggatttcc ctggttactc aatcggcggg ttatctgtcg
      721 gggaacctaa atcagaaatg aatcgtgtat tagaattcac tacaccgttg atccccgaaa
      781 acaaaccacg ttacttgatg ggtgtcggtg ctgctgattc attgatcgat ggtgttatcc
      841 gtggagtaga catgtttgac tgtgtcttgc ctactcgaat cgctcgaaat ggcacatgta
      901 tgacttctca aggccgtcta gtagtgaaaa atgcgaaata tgcccatgat ttccgtccaa
      961 ttgatgagaa atgtgattgt tatacatgta aaaactatac acgtgcctat atccgccatt
     1021 tgatcaaatg tgatgaaaca tttgggattc gtttgacttc ttaccacaat ttatacttct
     1081 tgttgaatct aatgaaacaa gtacgtcaag caatcatgga tgataatttg cttgaattta
     1141 gagaagcctt ttttgaagaa tacgggttca ataaagaaaa cgcaaaaagc ttctaaagga
     1201 aaatctttta aaaattaagt aaaaaactag tgttatcagc atttttctgc taaagtgttt
     1261 tttgtagata cagaattagt gaggtgaaaa aaatgggaac attaccaatg cttgtgatgt
     1321 ttatcgcgct attagcaatg tggtttttta tgtcacgttc gcaaaagaaa caacagcaag
     1381 aacgtcaaaa cttgttagat agcatgaaac caggtgattc agtcgtaacg atcggcggat
     1441 tacatggagt tgtttcagaa atcgacaatg acaaacggac agttgtttta gactgcgaag
     1501 ggatcttcct tgagtacgat cgtgcagcaa tcaaaacggt caaaccaggg actgtcgtaa
     1561 caaatgatgc aacgactact gttgaaacaa cagaagaacc agctgagaca gttgaagtaa
     1621 aaactgaaac aacagaaacg ctggaagaga cagaagagaa ggaagaaaaa taagtatcaa
     1681 agcttattta aagacgaggt agggcagaaa gatgtcctac ctcatttttt attcaaaaaa
     1741 gaaagagata agagcatggg atatattgct caatattgaa taatcgggtg tgtcatataa
     1801 ataataataa ataactttat atatttttct atacaaacac ctgtaaataa agcaatttta
     1861 tatttaaaaa taactgtgaa aaaaatcaca aaaaagtgtt tacatagaaa aataaatatt
     1921 gtatgatata catgtgaatt atttaacaaa taaccatgac ccattaggag gataatgatg
     1981 gctaaagtaa tagaaaaaga aaaaacgaag acaattgacg tacaagcaat gattgatgat
     2041 ttggcagaaa aagcaaatgc agcattgaaa gaaatggaaa gctttgatca agaaaaagta
     2101 gaccatatcg tgcatgaaat ggcaatggca gctttggatc aacatatgcc attagcgaag
     2161 atggctgtag aggaaacagg ccgcggtgtt tacgaagata aagcaatcaa aaatatgtat
     2221 gcgtccgaat atatttggca taatatcaaa catgataaaa cagttggtgt gatcaatgaa
     2281 gatgtccaaa aagggttgat tgaaattgct gaaccagtcg gtgtggtttg cggagtaact
     2341 ccaacaacga atccgacttc cacaacgatt ttcaaatcaa tgatcgcgtt gaaaacaaga
     2401 aatccaatcg tttttgcttt ccatccaagt gcccaaaaat cttctgcaga agcagcacga
     2461 gtggtacgtg atgctgctat cgctgccgga gctcctgaaa attgtatcca atggatcgaa
     2521 catccttcga tcgaagcgac ttctatgcta atgaaccatc caggtatcgc gatcgtctta
     2581 gcgacaggtg gagctggaat ggtcaagtct gcttactcta caggaaaacc agctttaggt
     2641 gtaggtccag gtaacgtacc agcttatatt gaaaaaacag caaaaattaa acgtgcagtg
     2701 aacgatttga tcgtttcgaa aacatttgat aatggaatga tttgtgcttc tgaacaagct
     2761 gtgatcgtgg ataaagaaat ctatgcagca gtaaaagcag aattccaagc acaccaagtt
     2821 tatatcgtaa aaccagatga attgcaaaaa ttagaagatg cagtgatgaa cgaaggaaaa
     2881 tatgcggtca atccatcaat cgttggacat tctgcgatgg aaatcgcaaa attggcagga
     2941 atcagtgtac caaaaggaac gaaaatgctg attgctgaat tggaaggcgt aggcccagat
     3001 tatccgctat caagagaaaa actttctcca gttcttgcca tgatcaaagc taacaacacg
     3061 gaccatgcgt ttgatttgtg tgaaggtatg ttgaatcttg gaggattagg acatacagca
     3121 gttatccatt cagaaaacga agagttgcat gtcaaattcg gtcttcgaat gaaagcttgt
     3181 cgtattttag tgaatacacc atctgcagaa ggcggcatcg gtgatatcta taacgaaatg
     3241 attccgtcat tgactttggg atgcggttct tatggtaaga actctgtttc tcgtaacgtc
     3301 tctgctgtaa acttaatcaa tgtcaaaact gtagcgaaac ggagaaataa catgcaatgg
     3361 ttcaaattac cgccaaaaat cttctttgaa aagaactctc tattgtactt agagaaaatg
     3421 gaaaacgttg aacgtgtcat gatcgtttgt gaccctggta tggtccaatt cggttactgc
     3481 gatacagttc gtgaagtatt ggcacgacgt aaaaatgatg tgaagatcga agtcttctca
     3541 gatgttgaac cgaacccatc gacaaatacc gtatacgcag gaacgaaact gatggcagac
     3601 ttcaagccag atacagtaat cgctcttgga ggcggttctg caatggacgc agctaaggga
     3661 atgtggatgt tctatgaaca cccagacaca tctttctttg gtgcaaaaca aaaattcttg
     3721 gatatccgta aacggacata taagatcgac aaaccagaaa aaacacaatt cgtatgtatc
     3781 ccgacaacat cagggactgg ttctgaagta acgccatttg cggtcatcac tgacagtgaa
     3841 acacatgtga aatatccgtt agcagattat gcattgacgc cagatgtcgc aatcgtcgat
     3901 cctcaattcg tcatgtcagt tccagcatct gtcacagcag ataccgggat ggatgtgtta
     3961 acacatgcaa tcgaatccta tgtttcagtc atggcttcag attatacacg tggattgagc
     4021 ctacaagcaa tcaagttagt ctttgactat ttagaaaaat cagtaaaaac acctgatatg
     4081 gaatcacgtg aaaaaatgca caacgcttct acaatggctg gtatggcgtt tgctaacgca
     4141 ttcctaggta tttgtcactc agtcgcacat aaaatcggcg gggaatacgg gatccctcat
     4201 ggacggacaa atgcgattct tttaccgcat attatccgct ataatgcaaa agatccacaa
     4261 aaacatgcga tgttccctaa atatgactat ttccgtgcag atacagatta cgcagatatc
     4321 gcaaaattct taggtctgaa aggcgaaaca acagaggaat tagtcgaagc tttagcaacg
     4381 gctgtttatg aattaggaaa atctgtcggc atcaacatga gtctaaaagc tcaaggagtc
     4441 acacaagaaa cactagatac aaccgtagac cgtatggctg aattagctta cgaagaccaa
     4501 tgtacgacag ctaatccgaa agaaccattg atctctgaat tgaaacagat catcattgat
     4561 gcttacaacg gataagcaaa agaaagcgta gaaaaaagat aagaaaatag atgaaaaaga
     4621 acttggaaaa cgttgtttct ccaagttctt tttttaattt ccaagtaact gaaagttact
     4681 tttgttattt aacatttagg tcaattttag acagtttttg ttcaaaaagc gatatttata
     4741 gtggacggta ttactgctat attaaggata taaaatgaaa gcgtttaaaa aggtggcgta
     4801 aagatgatta ttaaagaaga gatttttgta cctaaagaat tagtgaaaga aaaaattgac
     4861 ctgctcgttg aaaacctgac aacgatcaaa gacgataatg gtgaattttt gttggacttt
     4921 gatggactga aagtagatga caaaagctgg acagtgtgga attggccaca aggtgtcggt
     4981 ctatatggta tttataaaaa ttaccagatg acaaaaaatc ctcgcgctta tcaagtggtc
     5041 aatgaatggt ttgaggatcg tatggaagaa ggcgctccgc ccaaaaacgt caatacaatg
     5101 gcaccgctat tgactatggc ttacttgtat gaagacacga aagattcacg ctatttgcct
     5161 tatttagaac aatgggcaga atgggtcatg aatgacatgc ctcggacaaa tgaagacggg
     5221 ttacagcatg ccacatatgg accggaaaat aagaatcagt tgtgggacga tacattgatg
     5281 atgacagtgc ttcctttggc aaaaatcggg aaactgttga atcgcccaga atatttagaa
     5341 gaagctcgtt accagtttat gatccatatc aaatacttga tggataaacg aacaggattg
     5401 tggtatcacg gctggacgtt tgaaggaaat cataactatg ccgaagcatt ttgggctcgt
     5461 ggaaactgct ggttgacgat tgctattcca gagatcattg aaatcttaga attatcgaaa
     5521 gaagatgcat tgcgcaaatt attgatcgaa acacttgaag cacaagtgcg tgcattaaaa
     5581 acttatcagt ctgaaagcgg tttatggcat acgttgttgg atgatccttc ttcttacgta
     5641 gaatcttctg caactgcagg atttgcttac ggtattttga aagcggtcca taaacgttat
     5701 ttaccacaag aatataaaga agtcgcttat cgtgctatcc aaggattgct tgaacaaatc
     5761 gatgaaaaag gagaagttca aaacgtttca atcgggacag gaatggggga cagtttagat
     5821 ttttatcgga atatcggaat cacagcaatg ccttatggac agtcgttaac ggtgctttgt
     5881 ttgacagaat tgctcgtctc ttattgttaa aagaaaggaa acccatatga aaaaaacatc
     5941 actgctgttt gcagcaagtt cgcttagcct aggtctgcta ggtctaagcg gctgcggaaa
     6001 taattctagt gtggcaactg tcgcagatgc agatgtaaat gagatagtta ccttgcgctt
     6061 tgcttatgca agcaacagcc agccagtaat tgatgcaatg aatgaatttg ggcgtttagt
     6121 aaaagaaaaa acagatggtt ccgtacagat ccagtatttc ccagatggac aactgggtgg
     6181 agaacgtgaa ctgatcgaat tgacacagtc aggagcagta gatttcacaa aagtaagtgc
     6241 ctcagcgttg gaaagtttct ctaaagatta ttcgattttt tcagttcctt atctattcaa
     6301 tgatgaagaa catttcttta aggtgatgga taatgaagaa ataatggagc caatctacca
     6361 atcgaccaaa aatttaggat ttaccggatt gacctattat gattctggtc agcgcagctt
     6421 ttatatggta gacggtccga tccatacgcc ggaagatttg aagggaaaga agatccgtgt
     6481 gatgcaaagc gaaaccgcta tcaaaatggt agagctttta ggcggttcgc ccgtacctat
     6541 gggaagtgat gaagtgtaca cgtctcttca atccaatttg atcaacggat cagaaaacaa
     6601 tgaatttgtc ttgtatacag ctggacatgg tggtgtggct aaatactatt cctatgatga
     6661 gcatacacgt gtgccagata tcatcatcat gaatgatgcc atcaaagaac agctaactga
     6721 tgagcaggaa aaagccattg aagaagcagc gaaagaatca acggtttttg aaattgaagc
     6781 ttttgcaaaa gcaattgaag aagaaaaagc tttagcacaa gaagaacatg gagtccaatt
     6841 caatgatgta gataatacac cgtttcgaga ggcagttgcc ccacttcatg atatattcaa
     6901 aaacgatcct acctacaaag acctttatca aaagatccaa gagcaaggag cgtagctgtg
     6961 atgaaaatga ttttaaacaa ggtattagag atcctgggag ctgttttgct tgttgggatg
     7021 gtcgctgttg ttttatggca agtattttcc agaacggttt taggaaatcc aaatacggtc
     7081 acggaagagc ttgttcgatt cggtcttgtc tggtttgcca tgttgtcttc cgcgtatgtt
     7141 gtgggacaaa aagcacattt agccgtaacg gttttaagtg aaaaattaac tggcaaaaaa
     7201 agtaaaattt tagaagttgt tgttcaaagt ttatttctgg tatttgctgc gatgatcatg
     7261 gtgtatggcg gatggaatgc tgtcacattg acaatggggc agatctcgcc ttctttaagt
     7321 attcctatgg gatatgttta tctgtcagta cctgtatcgg gggtactcat cattatctat
     7381 agcctgatca atctaatcga tacattaagc aacaagccag caattcaaga aaaaatataa
     7441 aaatggagga ataaaatggc aatagaagcc ggattagtgt tattttttgt atttgttgtg
     7501 ttgcttgtat tagggatgcc gattgctata agtattgcat tctcatcgat gatgacttta
     7561 ttgttagtta taccgtttga tgtttctgct tttagttcag ctcaaaaaat ggtgggaagt
     7621 atcaatagtt tttcgctgat cgctattccg tttttcgttc tctcgggcat tatcatgaat
     7681 aatggaggga tagctaagaa actagtggat tttgcgatgt tgttcgtcgg gcgcgtgccg
     7741 ggggctttgg ctcatacgaa tgtgttaggg aatgctttat ttggttccat ctctagctcg
     7801 gccattgccg cttctaccgc gattggcgga gtgttgatcc ctcagcaagt ggaagaagga
     7861 tatgaccgga agtttgcgac agcggtcaat atcgcgtcag ctccgacagg tatggtcatt
     7921 cctccaagta ctgcttttat catgtattca cttgttgctg gtggtgcttc gatctctgct
     7981 ttgtttatgg gaggttatct cgtaggcgct ttgtgggcgc taggaatcat gctagtagca
     8041 ttcatcgttg ctaaaaagaa taaataccct gttgtcgaaa aaggacagat ggctcatgct
     8101 ggaaaaataa taaaagaggc gattcctagc cttctattga ttgtcatcat tatcggtggt
     8161 atcttgacgg ggatatttac agcagtagaa gcttcagcga tagctgtcat ttactccctg
     8221 ttgattgcta tgttttacta taaaacggta aaactaaaag atatacctaa tatgttgttt
     8281 caatcagtag caatgtcagg gacgatcatg ttcttattgg ctacttcttc catgatgtct
     8341 ttcgccatgg cgtttaccgg tattcctcag gcaattagtt cgttgattat gggcgtaacg
     8401 gataataaat ttattattct gttattagtc aatcttgtgt tattactggt gggtatgttt
     8461 atggatgtgg cgcctgctat cttgattttt acaccaatat ttttaccaat cgtcacaagt
     8521 gtaggggttg atcctgtaca ttacgggttg ttttcaatca tgaatctgtg tgtaggctcc
     8581 atcacgccgc cagtaggtac aggactatat gtcggtgcaa gtgtaggagg cgtaaaagca
     8641 gaggcaatgc tgaaaccgct tcttcctttt tatggggtta tcttagtcgt cttgtttttg
     8701 attacttact tcccgcaaat cgtcatgtgg ctacccaata tgctgagtta ggagaatagt
     8761 tatgttgaac attacaatta gaggacatga tctttccgaa gtccaaacga tagaagatct
     8821 tgcagaaaaa acaaaagaac aagggattca tacactgcag ctcgccttag gtctttcgtt
     8881 tcctgaaata ccttctggcg caaatgagat caattctggg atgggaaatt atgtcaaacg
     8941 agttttagaa aagcaagaag tgaccgtagg aattttaagt tgctatatca atatgattca
     9001 tccagattta acgatacgac aagagttgct gacaaagttc gagcagtatc ttcgctatgc
     9061 ttcttccttt ggtgcgtcga tggttgcttc ggaaactgga tgtgttttgc cggaaatcca
     9121 atatacggaa gaaaatttca cagatgaagc atttgctgaa gctgtgtccg ttatccgtcg
     9181 cttggtaaaa gctggagaaa aataccaaat gatggtgggg atagaaccag gtttgaatca
     9241 tccggtgtat tctttagcaa gggtagagca gctgatccaa gcagtagatt cggactatct
     9301 aggaatcatt ttagatccga ccaatttgat cacaagtagt gattatcaag aacaagtcca
     9361 attggtagaa gaagcttttg aacgttttgg tgaaaagata tgtgcggttc atttgaaaga
     9421 ttttcgtgtc gaacaggaaa aaatcgtgcc ggtaaatttg ggagacggtg tgatcgagta
     9481 cacaaaaatc aaagaaatca tcatgaagaa tcgtccgtac ctgtatgtgg ttcttgaaga
     9541 aacaaaagat gatgggattc gttatggaag aagtcttctt gaataatgta aagaagacgt
     9601 tggttaacta atatttagaa tggagggggc ggggctagaa gatgccacgt ctcttctttt
     9661 ttataagagt atataaaagc agctcttttt gattacaaaa aacgtggtat aataaaattg
     9721 tgcataagtg aacaaaagga ggtgcggcac atgctccaaa agaaaatcag cggtgaacaa
     9781 gtcaatacga tggtttctga tcagtatgaa atctatcatg tcaaagatgt cgtcagccaa
     9841 aataaaacga tctatcatca tcatgatttc tatgagatcc atgctacatt aaagggagaa
     9901 gcgacttttt atttgaacgg acgacaattt acgatcaaag caggaagtgt gctgctcatc
     9961 cattccaatg atttgcatcg tatcgtccgc caatcttcag atgtattcga gcgtgtctat
    10021 atctttgtca ccccttcttt tctagaaagt cgttccacgc catggtctaa tctatcggct
    10081 tgttttcaac caatgggaga gaagaggagt cgtgtattgc aaatagaaca ggaagtattg
    10141 aagcaaaaat tatcatttat cgaccatcct cctgataaaa aaatttacgg tgaagacata
    10201 aaatatgaac aagctctggt agaatacttg atttttctca atcaagttgt acaaaaagaa
    10261 gagagtgcgc aagaacagaa tgctgtagtt cctaatgagc gtgtggaaca aatgttacaa
    10321 tatatctcaa aaaatttatc tcatccgctt tctttagagg aaatggaaaa gcagtttttt
    10381 gtcagcaaat accatatcac acgagaattt aaaaagtaca ctggatttac gtttcatcag
    10441 tatgtaatga agaaaaagct gatctatgcc aagcacttgt tgcgagaata ccgcagctct
    10501 agtgctgtat atagtaaaag tggtttttct tcttatccgc attttctgaa agcattcaag
    10561 agagagttcg gcataacgcc taaagaattt ttgaaacgtg atacacagaa acagttggtt
    10621 cattatgaac attttgaaga tgaacaatga gaatgatcac taaaaaataa ccgcagtagc
    10681 tgctgttgtt tacatagaag cagaaactgc ggttatttta tttttatcta tatatttcaa
    10741 aatattttga aaaaatgacg tacatattat atgaatcagc tgaatttacg aaagtctctc
    10801 ggcgatagtc ctgtttttgc tttgaacagg cggctaaagt aagcaaaatt ctcaatccct
    10861 atttcttcgg aaatcattcg aaccgtaaat tctgtatacc gaagaaggtc tttagcgtaa
    10921 gaaagttttt tgctgatcaa ataatcgatt ggtggagaac cgataaattt ggaaaaatct
    10981 ttgctcagct gatatttatt caataagaat tgttgttcta attgatcaag tgtaatcgtt
    11041 tctttgaaat gttcgtctaa gtattgcttc agtttgtaaa cgtaggcggg aatatcctct
    11101 tcttcgaaat ctagctgata cttttgcaaa atcagttcat tcagcaactc gtggatagct
    11161 acagaggact ggaaatcggt acgggcattc gtgccttgtt gcatgtggat caattctgtg
    11221 atcaaatggt ggatcttgtt ttctgatgga tctcctgttg aatggaaggt gttatggccg
    11281 tcttttgtga actcctgata aaatgattgg acgttctgac cattcaaatg gatccaatcc
    11341 atttcccatg gttcttcgct gatcgtttga taacgctgat attcttggca gtcaataaaa
    11401 aataagtctc cagcttttag ctgttgctga ttatcattat atgtaagcga acctttgcca
    11461 gacaaagtaa actttatcaa gtaagaaggt aaatgtgctc gttcagtata gtaagggatt
    11521 ggtgctttga agtaaccgat ttcttggata taaaaaaata aattcctgct tctttgtgta
    11581 ggcgtcaaga tcactctttt tgagtcttcc gaccatgagt ggttggcttt ttcccagtaa
    11641 tccatgtaaa cactcccaac ttgtcaagat aatgcaatta tataccaaaa tagtgtgaag
    11701 caaaatataa gattctgtat tatgatagca ttgtcaataa atgataacgc tttattaata
    11761 aagtgctaat caacaataaa gtaaaagagg tggagaaatg aatccaacat ttgttgccat
    11821 cgatatcggt gcatcaagcg gacgactaat gaaaagtacg agggatgcaa aaggttcttt
    11881 gatcttggaa gaagtacacc ggttcaaaaa cggctttcgg aacaaagacg gtcacgatcg
    11941 ctggaagatc gattatctta tcaaagagat tttgattgga tttgaaaaat taaagcagac
    12001 agggattgat cgcctttttg cggggatcga tacatgggca gtcgattact gtctgattga
    12061 tgaacaaggg gatcggataa atgatccgat tgcttatcgg gacaagcgta ccaatggagc
    12121 agtagaacag ttttctgaaa tctattctct agataagttg tatgagcaga cagggattca
    12181 gatccagcct ttcaatacct tgttccaatt gtttgctgaa gaaaaagaaa atttggcaaa
    12241 agcacataaa ttgttactga tacctgatta tttagggtat gtctttactg gtaacatggt
    12301 gacggagaaa actaatgcat ctactatgca gctgctgaat gcagggacaa aagaatggga
    12361 aatagaactt cttgaaaaaa tcggtgtctc gaaggaatta tttccaccat tgacagagcc
    12421 gggaacgata ctaggagatc tgcaaaaaga acaattttca aaatatgatt tgccagatgt
    12481 gacctttatc acagtagcaa gtcatgatac ggcgtcagct gtattaggaa cgccaggtca
    12541 aggagaacgt tggggttata tcagcagtgg gacatggtcg cttttaggga ttgaaacaaa
    12601 gatcgccaat gtttctcgca atgctttttc tgaaaattat acgaatgaat ggggtgccca
    12661 taacacggtg cgttttttga aaaacatcat ggggatgtgg ttgatccagg aagttgcccg
    12721 aatgcaagag tacgagtaca gttatgcgga attggcagag cttgctgcaa aagaaaaacc
    12781 gctgcagcaa gtgatggaaa tcaatgaccc tcgatttttg aatcccccaa atatgataga
    12841 agagattcag caatactgtt ttgaaacaga gcagccagtc cctgtctcat cgggagctat
    12901 cgctcgttgt gtgtatgata atcttgctct ttgttacgca caagagctga tcaaagtaga
    12961 acacttaact ggaacgaaat tggaaaagct gcacatcgta gggggcggat cgaataatcg
    13021 tctactgaat caattgacag cagattatgc cggaatcatt gtagaagcag gacctagtga
    13081 agccacagca atcgggaatg ttgccatgca aatgctcagt acaggtcagt tttcgaatat
    13141 agaacaagca agaaatgtaa tcaaacagtc gtttccatgt gaaacttttt acccagatga
    13201 aaataagcaa aacacgatgg aatggtacgt gaataaaatc aaaggagtaa tcgtatgaac
    13261 acgattgaaa gaaattacga acaagcaaaa gaaaaatatg caactatcgg tgtagataca
    13321 gatgctgtac tagaaaagat acaggacatc aaaatttcta tgcattgctg gcaaggagat
    13381 gatgtcaaag gtttcttgac accggatggc gaattgaccg gtggaatcat ggcgacaggg
    13441 aattttccag gagccgcacg aacacctgaa gagcttagac aagatctgga gaaggcttat
    13501 tcgttgatac cgggcaaaca caaattgaac cttcatgcta tctatttgga tacagaagaa
    13561 tctgtcgatc taaatgaaat tgagccgaaa cattttgaaa aatgggtaga gtgggcaaaa
    13621 aaagaagaaa tcggtcttga cttcaatccg actttctttt cgcatccaat gatgaaagac
    13681 ggctttacat tggctcatcc agataaagaa gttcgtgaat actggatcga acacgggaaa
    13741 agaagccgca aaatcgcgga gtactttggg aaagaaactg ggcaaacaag tatcaataac
    13801 ttttgggtac ctgatgggat gaaagataat ccgattgatc gttttacccc acgggaacgt
    13861 ttaatggaat cactcgatga aatttttaca gaagagttag atgaacggta tgtacaagat
    13921 gcagtagaaa gcaaactatt tggtttaggc gctgaagctt atacagtcgg ttcccatgaa
    13981 ttttatatgg gttacgggtt gactcgtgac aaacttgttt gtctagatgc tggacatttt
    14041 catccaacag aagtgatttc caataaatta tcttcattag ctttattcag caaaggaatc
    14101 atgttgcatg tttcccgtcc agtgcgttgg gattcagacc atgtggtttt gatggatgat
    14161 gaattgcagg aaatcgctaa agaattagtc cgtaacgaat tgttggaaaa aacaaatatc
    14221 ggtctggatt tctttgatgc aacgatcaac cgtatcgctg cttgggtcat cggtacgaga
    14281 aatacacaaa aagcactgct gaaagctatg ctggaaccag ttgagcgatt gaaagaaatg
    14341 gagctggctt ttgactttac ttcaagaatg gcttatacgg aagaattgaa agatttcccg
    14401 tatgccgatg tatggaatta tttctgttac aaaaatcaag ttccagttgg tttggattgg
    14461 ctggaagaag tccaggaata tcaaaaagac gtgttggaat taagaaaata ggagtgtggc
    14521 tatattgaaa aaaatagata ttttacaagc gccttatgtg aaagaaatga tcgaaacgac
    14581 gtcgaatctt tatcgcttgg gatgggatga aagaaatggc gggaatattt cttatttact
    14641 aaaagaagaa gagatcacac cgttcttgga tcctgaaaaa gtgatccgcc gcatctcgat
    14701 gatttttgat gccagccgtt tagcaggatg ctattttatt gtaactggtt caggaagata
    14761 ttttaaaaat gtagcgagcg aacctgccga gaatcttgga atcgttcgag ttgctgaaga
    14821 tggcaaaaca ctggaacttt tgtgggggct ggaaaacgaa tgccttccta caagcgagtt
    14881 gccaagtcat ttcatgagtc atatcgcccg tttagaagta gacccagata atcggatcgt
    14941 tatgcattgc catgctagtc atctattagc gatgagtttt acgcatgaat tagacgaacg
    15001 ttcctttagt cgtacgctat ggcaaatgtg tacggaatgc ttagttgttt ttccagaagg
    15061 aatttccatc attccgtgga tggttccggg aacaaatgag attggggaag caacagctga
    15121 aaaaatgaaa gaaactcgat tggttttatg gccacaacat ggaatctacg ggtcaggaaa
    15181 agacatggat gaagtctttg gtttgatcga gacagcagaa aaggcagcag aagtctatac
    15241 gtacgtcaaa gcgcaaggac caatcttgca aacaatcacg gacgaaaacc tgtggcattt
    15301 agcagatgcg tttggtgtca ctccaaaagc aggttatttg gaggaagttc atacgaaagc
    15361 aggtgtctga catggtgaaa aaagcttttt gcatgaaagt ttacccagaa aaacaagaag
    15421 aatacaaaaa aagacatgat gaactttggc cagaaatgcg tacagcactt cgtgaacacg
    15481 gggtcatcga ctattcgatc tatcttgatc cgagtacaag tttgttattt ggttacttag
    15541 tgatcgaaga tgaaaagtta tgggaaaaaa tggcaaatac atctatcaat caaaaatggt
    15601 ggaagtacat ggaagatatc atggagacaa atccagatgc ctctccagtc agttgggaat
    15661 tgatgccagt ctttgaactg tagcaacaag caactgggca accggttgct tggggttctt
    15721 tcgtttttat tgtgaaaaat aatacaaatt aggaggaata gaaaatgagt aatcgaatga
    15781 ttttaaatga aacatcgtat tttggaaaag gagcgattga gtcgatcgtc cctgaatttc
    15841 agcagcgagg attcggcaaa gcagctgtca ttactgacaa aggattgatc gagcacggta
    15901 tagcaacaaa agtaacagaa cttctagata aagcagcaat cgcttatgct ttatacgacg
    15961 ggatcgtacc taatccaacg atccaaaatg taaaagatgg agtggctttt gttaaagagg
    16021 cagaggcaga ctgtttgatc gcaatcggtg gaggttcgcc aatcgatacg gcaaaagcca
    16081 ttgggattat tttgacgaat ccagagtttt cagacgtcat tagtttagaa ggtgttgctg
    16141 atacgaaaaa tccatgttta cctatattag ctataccaac gacttctgga acagcagcag
    16201 aagtaacgat caactacgtc atcacagatg aagtaaatca ccgaaaattt gtttgtgttg
    16261 atcctcatga tatcccaatc gtcgcgttca tcgacagcga tatgatgatg ggaatgccga
    16321 aaaaattggc tgcatcaaca ggtatggatg ctatgacgca tgctattgaa gggtttatca
    16381 caaaaggcgc ttgggaaatg actgatatgc tgcatttaaa agcaatcgaa atcatcggcc
    16441 attctttgga agcttctgta gatggcgatc aaaatgggcg agaaaaaatg gcattaggac
    16501 agtatattgc gggaatgggc ttctcaaatg tcggtttagg actggtacac gggatggctc
    16561 acccgttaag tgcatggtac aacattcctc atggcgtagc gtgtgcagca cttttgccaa
    16621 ctgtcatgaa atataacaaa gaatatactg gagaaaagta ccgtgagatc gctcttgttc
    16681 tagggattaa aggagcagct gaaatgtctt tagaagatgt aagagaagcg gcttgtggtg
    16741 agatcgatcg gttgagcaaa gcggttggaa tcccagaaac catttctgaa ttaggtgtaa
    16801 aagaagcaga tattccagca attgcagaag atgctttgcg agatgtatgc acaccaggaa
    16861 atccaagaga aacgacagta gaagaaatca ttgctttata tcaaagtttg atgtaaaaac
    16921 gaagcggatc ttcaacatta aattgcctgt aaagagaaat ggtagtttat atctggatat
    16981 ctcttttaaa ttgatggtat ttccgctata atttttctta taaagaaata ggagaatatt
    17041 atatggaaaa taaaaagcct tatggaactg tattgatcaa agcctctaaa atactagact
    17101 atttagcgga aaaccaagat gtctctttgc agacgatcgc aaagggtgtg ggaatgacct
    17161 cttctacagt cttgaaaata ctagatactt tgttgatgat cggctacgta aataaaaatt
    17221 cagagaaaaa ctatcgttta ggtgcaaagc ttattcgcta cgcgaataaa aacattgaac
    17281 aaatcgattt ggtagagttg actttaccgt ttttagaaca gctgcagcaa aagatcgatg
    17341 agactatcca cttaggggta ttggacaaca atgagatctt gtacgtgaac aaactagatc
    17401 caaaacatca aacgatccgc atgtcttcaa aaatcggaat cacccgacca ttatacaatt
    17461 ctgcgatggg caaagccgta ttagcagaat tcagtgaaga gcagtacact gattatcttg
    17521 aaaagcatcc gttgatccct tacacagaat atacgatcac caatgcatta cggttgaaaa
    17581 aggaaatcaa aacggtaaaa gaaacccaca tcgcatttga cgatgaagaa atcgaacgtg
    17641 atattttttg tataggagcc tcaatcgtga aaaacgaaca aatcattggt gcatttagtg
    17701 taagtatgcc gaaatatcgt ttaacagatg agacaaaaga acaaataatc agtgccctca
    17761 agcaaacaaa aagcgaaatc gagcaaagaa ttcaaaaata atgaaaaaag cgtttgcaat
    17821 ttttcttttc tgccgtataa tatgggtata gatttccaag ttataaaata aaatttctaa
    17881 ataggaaata ggtggagaag atgaaaaaaa ttgatatttt atctcgattg aaaaacgccg
    17941 gagtgattgc ggtggtacgc ggaaaaagca aagaagaagc tttgaatgct tgccacgcaa
    18001 tcatcaaagg tggtctaact ggtattgagt tgacttttac agtccctcaa gcagatcaag
    18061 taatcaaaga acttttgtca ttctacaaag accaaccaga aatagtgatt ggcgcaggca
    18121 cagtattaga cgctgtcaca gctcgcttgg ctatcttagc tggcgcagag tatattgtta
    18181 gcccttcctt tgatcaagaa acggcagaga tgtgcaatct gtatcaaatt ccttacttac
    18241 caggatgtat gactattacc gagatcaaaa cagcgctgaa aagcggggta gatatcgtca
    18301 aactatttcc tggaagcgct tatggaccaa gtatcatttc tgccttcaag gcgccgatgc
    18361 ctcaagtcaa tatcatgcca actggcggtg tgagtctgga caatatgaaa gagtggttcg
    18421 atgctggtgt cgtaacagtc ggagtaggtg ggaacctttt agcacccgca gctacaggag
    18481 attttgacaa agtaacggaa gtcgcgcaac agtatgcagc aaaaatgaaa gaaatcaaga
    18541 ggtagctgct tatgggaaaa gtagtgacac tcggagaaat catgttgcga ttgtccacag
    18601 agcagggaac ccgtatcgat tcaagtgaac gattcgctgc ccattatggc ggaggggaag
    18661 caaacgtagc aatttcttta gctaattacg gacatgaagc gatttttgct acaaaagtac
    18721 ctgataacgc attgggaaaa gcagtcaaaa agcacttgca atgttatgga gtagatacga
    18781 aacaggtatt atctggtgga tcaagactag gtacttatta tatggaaact ggtagtggcg
    18841 aacgcgccgc ctcagtgatc tatgatcgtg ccggatcaag ttttgctgaa atggatcatt
    18901 tggaatggtc gctagaggag ttattccaag gaatagatat atttcatgtt tcaggaatca
    18961 ccccagcttt gtctaaaaaa tggcaaaaaa tgacgaaaca ggtgatagaa gctgcaaaaa
    19021 aagctggctg cctgatcagc ttcgatatca actatcgtgg aaaattatgg acacagcaag
    19081 aagccagcga agtaatccat cagcttttac ctttagtaga tatctgctca gctggaaaaa
    19141 tggatgctct ttatttgtta ggtatcgaga aagcgccaga agcagaagaa caacctctaa
    19201 tttattatta tcaaaaaatg caggaaaagt tcccgaatat tcaggtgttt tattcgacca
    19261 agcgtaccgt tcattcagca agtgaaaatg aattgaaggg gacattgtgg atgaaccatg
    19321 aatatgtgga atcccaagtc catagaatca ccccaatcgt ggatcgagta ggtggcggag
    19381 atgcttttgc aggtggcgtg ctccatggga ttttatccaa tatgtctccg caagaaatca
    19441 ttgattttgc tacggcagct tctgccttga agcatacgat ccatggggac tgcaaccaat
    19501 ttagtcaaga agaagtcgca caatttttag catgcggctc tggaaaaatc attcgataga
    19561 aggagtagaa gaaaatgcaa gaaatggaaa cacgttatac acacagtcca gaagatatcc
    19621 gtcattattc aacggaacaa ttgagaaaag aatttttagt agaaaaggta tttgaaccag
    19681 ggaaaatcag tttgacttat acgcacaacg atcgaatgat ctttggtgga gtgacaccta
    19741 ctgaaaaaga attagaaatc acattagaca aagaactagg tgttgattac ttcttagagc
    19801 gtcgtgaact aggtgtgatc aatatcggtg gaccaggatt catcgagatc gatgggcaaa
    19861 aagaagaaat gaaaaaacaa gacggatact atatcggaaa agaaacacga catgttgtat
    19921 tttcttctca agatgctgaa aacccagcta aattctatat tagttctgtt ccagctcatc
    19981 ataaatatcc aaatgtaaaa atcagtatcg accaagtaaa accaatggag actggtgaag
    20041 gcctgacact gaatgaacgt aaaatctacc aatacatcca tccaaatgta tgcgaaagct
    20101 gtcaattaca aatgggttat acgattttag aaccaggaag cgcttggaat acgatgcctt
    20161 gtcatacaca tgaacgtcgt atggaagctt atgtctactt tgattatgcc aatgaagata
    20221 cacgtgtgtt ccacatgatg ggcaaaccag atgaaacaaa acatttagtt gtagacaatg
    20281 aacaagccat tatttcgcca agctggtcga tccattcagg tgtaggtaca agcaattact
    20341 cattcatctg ggcaatgtgc ggagaaaata tcacctatac agacatggat atggtgcaaa
    20401 tggatcaatt aaaataagca taagggagag aaaatgatgg aatttagtat ggatatgttt
    20461 cgtttagatg gaaaagtagc attagtcacc ggtgctgtct atggtattgg atttgagatt
    20521 gcacgctctt tagctacagc aggagcaaaa atcgtattta ataacttgaa tcaagaatca
    20581 gttgatgaag gtatagcgca ttataaagaa gcaggcatcg atgcaaaagg ttatgtctgc
    20641 gatgtgaccg atgaagaagc ggttcaagcg atggttcaac agatcaaaga agatgtaggt
    20701 tcagttgata ttctagtcaa caatgcaggg atcatcaaac ggacaccgat gatcgaaatg
    20761 gatgcggcag acttccgcca agtaatcgac gtggatttaa atgccccatt catcgtttca
    20821 aaagcagtta ttccggatat gatcgaaaaa ggcggcggta aaatcatcaa tatctgctcc
    20881 atgatgagtg aattaggacg cgaaacggtc agtgcttatg ctgcggcaaa aggcggatta
    20941 aaaatgctga cgaaaaacat cgcttctgaa tacggtcaat acaatatcca atgtaatgga
    21001 attggaccag gttatattgc tacaccgcaa actgctccat tacgcgaaac acaagaaaac
    21061 ggtgaacgtc atccattcga tcaatttatc gttggacgta cgccagcagc acgctggggc
    21121 gagccaatcg atttggctgg accatctgtc ttcttggctt ctagcgcatc tgatttcgtt
    21181 aacggccatg tcttgtatgt ggacggaggc atacttgcct atatcggaaa acaaccttaa
    21241 aagagcttta gtacactgtt tagtggagag gttgtgaaat cagcggattg aacgaatacc
    21301 gaaggacagc tgattaaaca tcatttattc gaaaaaagag gctgggacag aagcatttaa
    21361 ctccaagaaa taagaaggaa ttcacgaaaa ttgcttttca aatttttgtg aatttcagct
    21421 tatttccgaa ggagttgctt ttacttccgc cgtttgtacg tgtttagagc gtgagacaaa
    21481 agtgttcttt acttttgtcc cacgctcttt tctgtgcgtc ttccatactt cactaagtcg
    21541 atccctcttg cttcgcacca atccttcact ggtccggaaa agatcagaga ttgttggtgt
    21601 agggccgcgg tattcgttgc gccgaccata gtataaagca gacgaagctc ttcttgccat
    21661 tgcttcatca gtataatagt ttcttctacg ccgtgattca tcagatgcgt cagtacggtt
    21721 cctgaagtac ccacggcatt tgcgccgaga caaagggctt taaatatgtc ataggcattg
    21781 cggatacctc cggaggctag gatttccata gaagtgtctg cttcatttgc ttcaagcaat
    21841 gaagagactg tcgattgccc ccagtcagct aaataactca gttcccgctt ggagcgacgg
    21901 gcgttttcga tctgggtgaa gcttgttccg cttcgaccgc tgatatcaac tgtatgaact
    21961 cctaaagcag ctagatcatt gagcgtttct cttgtcatgc caaaaccgac ttcttttacg
    22021 atgaggggga cgtcaatggc tgtttgagtt tcttgaataa gtactttcca attggtaaaa
    22081 tcacggtctc cctcaggcat aaccaactct tgaggtgcat tcaaatgaat ctgtaaggca
    22141 tctgcgtgaa acaatcggat agcttctttg gctctttcga cagaagtccc tgcaccgatg
    22201 ttggcaatga ttttcccgtg aggatattct tgtcgcataa tcgtataagt atcggctaaa
    22261 gaagggactt tcaaggcagc gctgactgaa ccagtggcaa tcatcaaatc tgcttctctt
    22321 gcgacgattg caagatcttg gttgattttt tttgtttttt cgcttccgcc agtcatcgca
    22381 ttgatataaa atgggctgct tagtgtaaac ccaactgcct gtgtacttag atcgacatca
    22441 gaaactgcta tttgcggcaa agggttatgg atgatccgta cgaagtcaaa ttcgtttttt
    22501 tgtttatcat gaaaggcttt agctagtgaa acatgttcgt cttttcgatt catcggtttt
    22561 cctttctttg atcgctatag acatgtaacg gcagtggagt gatttctgct ttttcccatg
    22621 cactcattaa aggaagaatg ccagatttct ggtcaacaat tacgattccg caatcgcccc
    22681 cacctgcacc agaagatttt gcggctcctt catactgttc agctaaatta cacaatttgt
    22741 tcaaagcagg cgtttcgatg acgaccccag tgattgcaga taaatcatgc agtaattgtc
    22801 ggttttttcg aatcatctgt tggatcaacg ttacattatt ttctttaaac cctttgatca
    22861 tttcgttgac acattctgta ctatttttta agaaaagctg ataagccacc attttatctt
    22921 ctctcgaacg gtgaacttga tcgaccaaat cagaagtaga ggcagggcta cccgtccaac
    22981 caatcaataa acgtaaatct tcaggagcaa tcaatggctc aatggataga cctggccaat
    23041 ccagggcaag taactcactg atagaatgct gagtttcttg ttcttggagc caaggatggt
    23101 cgaaggttga gaaagcgatc cagccaccat aacagctagc agcgatgtcg ccgcaggaac
    23161 cattatcttg aactgctaaa ttggctagtg ctgcaatctt gaaaatctcc aactgagata
    23221 aattcaacgc gtaaaaaaca ttcaaggctt tgaccgttgc aacggtcacg gcaccgctag
    23281 aacccaatcc atatttccgg ccatttgaac tgtctaactc acttgttact ttcagatcat
    23341 aaaaggataa aagaatgttt ttttcttgtg catacttttc agtcaagcga atagcagcaa
    23401 ggatataatg aaaaggattt tcccgaatat ctaaaactaa ttctccgttg cgtcttgtcc
    23461 aacgtacagg catcccacta tattgtgcag attggatact tccgactttt cgtgcagatt
    23521 ctacagtgac tgtcacgaat tgatcgactg cagcgataac tgctggatgg cctgtttcaa
    23581 caactgcata ttctccggca atatagagtt tgcctggtgc agatacttca atcataaaaa
    23641 tctcccttta ttcaataatc gcaattcctg gaccagcatg tgcagtaatt acttgttctt
    23701 tgctaaataa tttggtaaat gtttcttgta cctcagataa atggctgttt tccactaaaa
    23761 ctttgacatt agggccagca tccatcgtaa agtagcatgg aatgccttgc tttctcaatt
    23821 gtcgcaccgc atccatcgct tttaagctgt caggagacca gtaagtgaat ggaggctggg
    23881 cagctaaagt cgttccatgc atttttagtc cgtttctttc catcgtttct ccgagaagtt
    23941 ggaaatcttt tgttttgatt gcttgtttca attgatatag atccccttca acggaatcta
    24001 accagccttg ataaaaactg gatgtttcga ctgtccgacg catcccattt ctgctggaca
    24061 cttctttttt ctggtcgttg atcaaaacga aaaccattgc taaatcgtct tcgaaagaat
    24121 cggaagggac tggcttagcg taagaactta agtcgtcatg gcctttttcc cattcgacga
    24181 aaccaccgaa aatacttcgg caagctgaac cagacccgcg tcgagcaaat cttgaaagag
    24241 agagatcatc taatccaagc ttaagagcag tattgcaagc gcctgctaaa gcagctagcc
    24301 cgctggcaga ggaggctaat ccagctgcgg taggaacgaa attctgactg attactgaag
    24361 cttttagtga gaggccggct tctttacgaa aaaggtcaag aaactgactg actttttttg
    24421 ttgctttttc gtcttgcaag gtgccatcta gataaaattc atctaccata tagctatcag
    24481 aaaagatgac ttctgtctct gtataaaatg catccaatgt taacgaaagg ctgttgttca
    24541 ttggaaggat gagttcttca tttttcttac cccaatattt gattagagca atgttggtat
    24601 atgcgcgtgc tttgccttta aacataggta tgtactccta atccttgtat ccaagtttca
    24661 gcagcacccg catcttcaag tgcttgactg atttcttggg cttttgtttt tgtttgtgct
    24721 aatgcaatca tacagccacc gcgtccaccg ccagttaatt tggcacccaa tgccccggta
    24781 tcttttgctg tttggatcaa tagattaaga aaatcattgc tgattgtcag cttttccaga
    24841 agtgattgtg attcatccat tgtctgtgcc aacgtttctg gtgaattttc aatgattgct
    24901 tgttttgctt gcttcgtcaa gtatcctaat ttttggatca tttgtccagt ttcatgaggc
    24961 tgggtttcaa agaggtgagc gacatctttg acggcttctc ttgtttgtcc tttgattcct
    25021 gtatcagcga caatcaaaaa agcatcgatg ttcaaagaaa agtagtcgaa aggatgccct
    25081 tttgtaaaat aaatcggctg caagctgcta gtagcggctg catcgattcc actaggatta
    25141 ccatgggcga ttttttccga aagctggaca ttttctaata gtatttcacg agacaaagga
    25201 aatgctaagt aatcataaaa agcacgagtg actgctgtgg cgactgcagc gcttgatccc
    25261 attccacgtt cagcaggaat cgtgctttca atggtcagtt gcaagttttt ttggatgtca
    25321 tgctgttttt ttaagtgaat gaataatttt ttgatatttt ttaatgcatg aggagcttcg
    25381 gctaaatttc ctgaatagta ggaagaaacc agttgatcgt ccattgcatc cagctcttca
    25441 aggaatgcgg tgacttttgt tgcatagaaa ggaaaggcaa tcgctggttc tccataaaca
    25501 accgcgtgct cgcccatcaa tatgatcttt ccgcttgatt ctccttggcc atagtttgcc
    25561 ataatctaac tccttctcac gtaaaagtga tttttaagca aaaaataaag cgcccaaaac
    25621 gagttgcgct gcttcacgaa tttttttgtc cactaagggt ctcaaaaaac attcctcctt
    25681 tattttacta aaaccatctc agaagtaaaa ctaagaatac gttttctaaa gaaaaaacac
    25741 ttttttctta agaatttttt gacttttttt cttctttgac tagaaaaaaa tacaattgac
    25801 actactagat attgggggta tatttaaaaa ggttggagtt aaacacaata tttagtgatg
    25861 aagtgagctg gaggtaaatg agcgtgatcg ttttagcagg tacaattggt gccggaaaat
    25921 caagtttaac agaaatgatg gctgaacact ttgatagtca ggcattttat gaatcgattg
    25981 atgataatga agtcttgccc ttattttatg caaaccctga acagtatgct tttttgctgc
    26041 aaatttattt tttgaataaa cgttttgcaa gcatcaaaca agcaatgaaa gatgacaata
    26101 atgtattgga ccgttcgatt tatgaagatt cactgctttt ccatctaaat gcagatctag
    26161 gaagagcaac agaaacagaa gttcgtgtgt atgatgaact gctggaaaac atgatggaag
    26221 aacttcccta tgctgcccat aaaaaacatc cggatttatt agttcatatt cgtgtatctt
    26281 ttgatacgat gttggagcgt atcgaaaaac gtggtcgttc gtatgaacaa ttgtcctttg
    26341 atccaagtct atacgattat tacaaagaat tgaacagacg ttacgatcaa tggtatgaag
    26401 aatacaaaga aagtccaaaa atccaaatcg atggagaccg ctataatttt gtggaagatc
    26461 ctcaagcaaa agaagaagtc ttgaaaatga tcgaagaaaa attagcagag attcgccaaa
    26521 ccaaagtagc catttgattt acagttgctc aaataaaggg taaaccttta tttgagcgac
    26581 ttttttcttt atactggaaa caaatgtcag gaggatagag tatgcgggaa aaacactatt
    26641 ttaatcaaga ccgtaatttt tggatcaatg tacagcaaaa cgatgtgcta gctgttaaaa
    26701 acttaaaaga agaatatggc attagtgacg agatgctgac ttattctcta gataaaaatg
    26761 aacgggcgcg cgtagagtac gattcttttg atgaagcgtt actgcttgta tcaaatgttc
    26821 cgcaccagca aaaagtcgat aatcattatg aaactagtcc tatcgctttt attttaaaag
    26881 aagacggttt gtttacattt accacgccga ataccgagta cgtgattcga ctaattcgat
    26941 cgcttttgga acgaatgcca gacatgagtg tatacagttt attgtttcgt acattgtttt
    27001 tgatttctga ttcctttttt cctttaatcg aggaagtgaa tagtgaacgt cagcggctta
    27061 atctgaaatt aagagaaaaa acaacgaaca agaatctgct gcaactttca gatttagaga
    27121 tcggtttggt ttacttagtt acaggaacaa aacaaaatgt agtactttta gaacaaatca
    27181 aggcattggc tatttatcgc aagttgtcag aaaaggaaaa agaagagttg gacgatgcgc
    27241 tgatcgaagc acgacaagca gttgaaatga cgaacttagc ttcgcagatt ttagaccagc
    27301 tctctggcac ttataataat ttgctgaata acaacttgaa tgacacgatg aaatttttga
    27361 cggtctggtc gctgatcttg accgttccaa ctattgtgac aggattcttc ggaatgaatc
    27421 tccagttacc ctttacccat tccgttttcg gatggggaat cgccttgatc atcagtttgg
    27481 tcttatctat ttggatgctt attgcactgt ggcggcggat tcgttgatct agtctttgat
    27541 ctgcaaacca agggcttggg cgatcacaag tgcttgctct tggttgacga ttagtcccgc
    27601 caaagaatct tgagataaag cgattgctgt gaagaaatta gtcgtaaagt ctaatccctt
    27661 cagagaagtt cgaaaccagt tcgaaccggt caactgattg tcagacaaaa aaaggttttt
    27721 ccaagtgacc tcataaaatt cgctgtcttc taattgacaa tgatcgaagg agacagcttt
    27781 caagtttgta ctactaaagg aagccatcga agcaatacaa tcagtgaaag tacagtctcg
    27841 aagataactt tcggcaaaat tcgtacctgt taatttacat tgatgaaaca cgacttggtg
    27901 gaaactgcca ccaatccact ccagattgga aaaatcacat ttttcaaaaa tgacattact
    27961 gcattcaaaa tgacgtaaaa ctgttttttg catcgtaagt ttttggatat gactctctct
    28021 taataccata tttttggcat cgagatagct ttggtcaccc ccgttgatca gaagaccaga
    28081 gaagatctcc tcatcttcta aataaaactc tccctttgta agaagaggaa gagaaggtgg
    28141 aataggttcg atttttttca tgtgggttca cctcgttttt ctttagtata gcaaagaagc
    28201 gggaatcact gctagaaagt ctgctaatct aatcattttc agaaaaggaa gacaaactgt
    28261 atgaaaaaca ttgacaaaaa gattagtttt tgctatacta tgatggttga gaaataaaag
    28321 cagaagcacc cgcttctcgc cttagttgat aatgtcactg ggctagatag ttttcactgg
    28381 ttctattagg tgaagtacgc gcgggttctg taagagaact cgttttttta ttgccgttta
    28441 ttcggtaagc ttttctttct ctcataatat ttggaggtga atgaccatag caaaggatat
    28501 gatggttaac gacggcattc gtgcacgaga gttacgattg atcggttcag atggtgagca
    28561 attaggagtt aagacaaaag cagaagcatt gaatattgca gaacaagcaa acttggatct
    28621 tgtgttagtt gcccctggtg cgaaaccacc agttgcgcga atcatggact acggtaaata
    28681 ccgtttcgaa caacaaaaga aagaccgcga agcgcgtaaa aaacaaaaag tgatcaatgt
    28741 aaaagaagtt cgcttaagtc ctacgatcga cttgaatgac ttcaatacaa aacttcgtaa
    28801 tgcacgtaag ttcttggaaa agggcgataa agtgaaagct tctatccgtt tcaaaggccg
    28861 tgccattacc cataaagaaa ttggtcaaaa agtcttgaat cgcttagctg aagaaactgc
    28921 ggatattgca acagtggaac aaaaagcgaa aatggacgga cgcagcatgt tcttgacgct
    28981 ggcaccgaaa aacgacagta agtaatttga atgactaact ggctgttgga cagccgatag
    29041 tcggataacg aaagattttg aggaggaaat atagtcatgc caaaacaaaa aacacaccgc
    29101 ggatcagcaa aacgtttcaa acgtactggt aaaggcggat tgaaacgctt ccgcgcgttt
    29161 acaagtcacc gtttccacgg caaaacaaaa aaacaacgcc gtcaattgcg taaagcaagc
    29221 atggtttcta gtggcgactt caaacgtatt cgccaacaac tagcaaaaat gaaataagaa
    29281 gtacaaataa cagaatctga agatttattt ttattaggag gaattataca tggcacgtgt
    29341 taaaggtgga acagtaactc gtaaacgtcg taaaagagtg ctaaaattag caaaaggtta
    29401 ctacggttca aaacacactt tatttaaaac agcaaaagaa caagtaatga attcatacaa
    29461 ctacgcatat cgcgatcgtc gtcaaaagaa acgcgacttc cgtaaattgt ggattgctcg
    29521 tatcaacgca gcagctcgta tgaatggctt gagctactca aaattaatgc acggtttgaa
    29581 agttgctgaa atcgacatca accgtaaaat gttagctgac ttggctgtta acgatgcagc
    29641 agcatttact gcattggctg accaagcaaa agaagctttg gctaaataag ctaaacaatt
    29701 ataaagagga aagaagataa cgaaaagtta tgttctttcc tcttttttta tttacaatcc
    29761 tccatcaaat gaaacaggac aataacgtat aagtctaaaa tagcataatt aaggtttttt
    29821 aattgaaaac tgaacattta tggtcaccct ttaatgaaag cgctaactac ataagttaga
    29881 atgagtttga ctgatatatt agtttgctta tcagaaaaac aaaatggacg gaggaataac
    29941 atgagtgata ttattattgg tattttgtta gttatctcat tctttttcat ggtctggtac
    30001 tgtgtaaaag gctacaactt gatggtcggc tttgccatca tggctactgt atggatggga
    30061 ttagcgctag tcggaaacac gttttcacca aacccggcga tggaagggca aggagtaatt
    30121 gatgtgttga cgcatatcta tacgacgggg ccagctgagt acgccaaatc gatcttggta
    30181 aatgtcttct ttggtgcctt tttcgggcgt gttctagtag atagcggaat cgcagctacc
    30241 ctgattcgaa aggtagttga acttggaggg gacaagccaa gaatcacgat gagcttacta
    30301 tgtattgtaa ccgctgttat attcatgtcg atgacaggaa tcggaccagt gatttctatt
    30361 gcagttattg tgttgccaat cttgatgtca ttaggtattt cagtaccggt tgcactgttc
    30421 tcatttatgg gctcgattat ggctggaatc tttgctaata tcgtcaattt caaacaatat
    30481 caaacgattt atgctggttt caatccagcg gctgaaagct atacttataa tgactatttc
    30541 caaattggta tgattgggat gattgtaagc ttagttgtgg tactaacggt cgctaatata
    30601 tcaatgaaca aaaagaaacg ctatgcaatg gcagcaaacg taccagctga aggtggcgac
    30661 gcaccaatga tctcatggtt agccgtatta ttaccagttt taggggtcgt tcttttagat
    30721 cttccaatca tcttaggttt tattctagca ggtatctggg cattgctgtt tactggaaaa
    30781 ttgcgcggag gttataaaga aatctgtcgt cagtttgcga aattatttac agatggcgca
    30841 gtagatgttg cgccaatggt tggtttcttg atgaccttag cgatgttcaa taattcagct
    30901 gcgtatgctt ctccttattt ttcagctatt tttggagatt ggataccgca atcaccatta
    30961 gtcttggcaa tcgtatttgc tatattgaca ccactaggat ttttccgcgg tccaatgaat
    31021 ctagtcggtt caggctcagc tattttagct gtcgtattag ctgttaatcc aacgatgtcg
    31081 ccagcctttt tgttcccgtt atttgcaatc acaacgattg ctcctcagca tttagatatt
    31141 acacaatctt gggttgcttg gggattaggt tatacaaaag taacttctcg agaatatatg
    31201 aagaaatcca tcccaactgg ttggatcatc ggagcgatct tatgcctgat cacgttctta
    31261 ttgtacggga acgcctagta aacaaaacgt cgataaaaac gattagatga atggaggaaa
    31321 agaaaatgaa acgttttgtg cgaatgggaa ttgatgttgg cggtacacat acgaaagcag
    31381 tcgcaatcga taatgcgacg cacgaaatca tcggaaaatc ttcagtgaaa acaacccacg
    31441 atgatgtccg tggagtagcc gcaggtgtcg ttcagtcttt tcaaaattgt ttgctggaaa
    31501 ataatatcag tccagaagat gttgtgtttg ttgcacattc taccacacaa gcgactaatg
    31561 cactgattga aggagacgta gcaaaagtcg gcgtaatcgg gatggcaaaa ggtggattag
    31621 aaggtttttt agcaaaacga caaactagat tgaacgatat cgatttaggg aataagaaaa
    31681 aaatagagat tgtcaatgca ttcttacctg tcaaacactt aaatgtagac cgtgtttcag
    31741 aaacgatttc ttctttagaa agagaaagag cggaggtctt ggtttcttct atggcatttg
    31801 gagtagataa tggggaacca gaacgagttg tttatgaagc agcatcggta aaatcgatcc
    31861 ctacaacgat ggcttctgac atcacaaaat tatatggatt gacaagaaga actcggacag
    31921 cagcaatcaa tgcatctatt ttaccaaaaa tgctagatac ggcaacctct acagaagatt
    31981 ccgtacgaga agcaggggtc aatgtttctt tgatgattat gcgcggagac ggcggagtaa
    32041 tggaaatcaa tgaaatgaaa aaacgacctg ttttaaccat gctttccggt ccagcagcat
    32101 cagtcatggg ctctttgatg tacttgagag cgtctaatgg tgtttatttt gaagtaggcg
    32161 gaacaacaac caatatcggg gtcattaaaa atggacgtcc agcaatcgat tattcaattg
    32221 taggtggcca cccaacatat atctcttcat tagatgttcg ggttctaggt gtggcaggcg
    32281 gttcgatggt acgggctaat cagtcaggaa tcatcgatgt cggtccacgt tctgcacata
    32341 ttgccggtct agattatgca gtatttacgg agacagaaaa aatcaaaggt cctaaggttg
    32401 aatttttctc tcctaaagaa ggagaccctg ctgattacgt caaggtagtg atggaagacg
    32461 gagaagaagt gactattaca aatacatgtg cagccaatgt ccttggatta gtgcaagaag
    32521 aacatttttc ttatggaaat gtcccatctg cacgaaaagc catccaagca ttagctgatt
    32581 attgtcatac gacggttgaa gacatcgcag aacagatcat ggaaaaatcc tatgctaaga
    32641 ttgaaccggt gattttagaa ttggcagaca agtatcactt ggagaaagat cagatttctc
    32701 ttgtaggtgt agggggcggc gctgcctcat tgattactta ctttagtaat aaaatgggtg
    32761 tgaaatattc gattcctgaa aacgccgaag tgatttcttc tattggtgta gcacttgcaa
    32821 tggtccgaga tgttgtagaa cgtatcatcc cttcgccaag taaagaagat atacgatcgt
    32881 tgaaaaatga agcgatgaat aaagcgattg aatcaggcgc tacaccagaa tcgatcgaag
    32941 tccacgtaga aatcgatcca cagacttcaa aagtaacggc tatcgctact ggttctacgg
    33001 aagtgaaagc aaccgatcta accaaggaga tcacaacaga agaagcacta gagcttgctg
    33061 cagaggatat gcgattaaat aaaaatgaag tttgcttatt ggaaaataca cctttctttt
    33121 atgtatgcgg cgaacagaat cgttcaaaaa atgctggaag tcttcggatc atcgatcaaa
    33181 aaggatttat caaggtccaa cgtggacatg cttcatgtat gaaaacaact gcagccaatt
    33241 atatgacagc tgtcgaacaa ctttgggaag atatggcagt ttatcaaact gaattgattg
    33301 cccgaccaga attttatctc tgcttaggag caagagtctc tgattttaca gcgacggatc
    33361 tggaacaact acagcttttg atggatctgg aagtatctac tatggaaccg gaggaagaag
    33421 tgatcgtcgt tgccggaaat atcaaacaaa cataagttag aagagttact aaacgaatta
    33481 caacagatcc ccgaagaaat ttggggattc taccagtttc ggcgagattt attttggaaa
    33541 aagattcctt tgtccaagca gaaaattctt atacaacaat caatcgattg tggtatcgaa
    33601 acggcatgta gcatcaaaaa aaagtaccct tttgccgatg taggagaaat ttgtgaacaa
    33661 atggctgttc caatcgtttc ctgtgaatca gagcaaataa acgaacgaat cacttttgca
    33721 acttatgcag aagatgaagg gattcgattg atgacggagc cgttagaaaa attaaaatgt
    33781 tcaggactag cttcgatctc taaagaaaca gcgcaagctt tgattattgg acatgaacta
    33841 tttcaccaca tcgaagcttc tgttaaggga atttatacgc aaagcgaaaa aattgtgctg
    33901 tggcggttgc ctttttatac acatcaatca aacattcgtg cattgagcga gatagcagcg
    33961 atgagttttt caaaagagat gaatcaaagc gatttttcgc cttatgtatt agaggcagtc
    34021 ttactttggc catataatga aattcgtagc caagggatct tagaagaaat aaaaaaaata
    34081 gaaaaaagat gtacggagta tgatttagat tacaaataaa gagactgtga caaaagtcgt
    34141 gtcacagtcc tttttttccg aataaacgat gttctcctgt caactcctcg gtcacaagtc
    34201 aaaatattca acaaacatga gaagctgttt tttgaaattg ttccttgtga ctcggagatg
    34261 aacggcaggc tcacgacctc ttggaaaacg gtgttcaaaa gcttgcatct gcggtaataa
    34321 gtccagccaa gttaaaaaca taagaagcta tttttacttg gctgttctta ttacttgatg
    34381 cagggcagct ttttcacaac ctctcaataa acggtgtgca atcagctgac cctcggtatt
    34441 agctcaaaaa aaacggcaaa atatgaggaa ctattttgcc gtttctttct ctaatactca
    34501 ggtcaaaacg ctgattccaa aacctcttat ttgatgggtc tgtcctgaat atcttcaaaa
    34561 taatcggggt aattatgaat cacgtattct tgctcctcga taatcatatg taaatgcatc
    34621 gtgcaaagaa atccgacttc atcaaagtta tgatcaatca ttgattgaag cattgtctga
    34681 tgttcatcta atactcgacc ccagtctaat tctgaaatcg tcaaacgtaa ccatctgaaa
    34741 cgcgtactat aactttctag ccaatcccaa atttctcgtt ttccagcaat ttcataacaa
    34801 gttcggtgaa aatcagtatc caaatcaaaa aaagcttttt tattttgagc gattactgcc
    34861 tgatcggttt gttctagtat tttttctagt ttagcttgat cttgcttggt cattttcgca
    34921 ctgcattctt gcaggatcgg tttttccaac ttttcccgcg tataacgggc taatgaagca
    34981 gatcggatat cgatttttga aacataagtg ccggactgtg gaatggtttt tacaagctct
    35041 tgattgcgca gttggatcag tgcttctcga atcggtgtac gcccgatagc tagttgttct
    35101 tctaacactt tatcggagat tttacttcca ggtgctaact cggaataaat gatttgttta
    35161 cgtatagatt cataagcttg ctgttgcaaa ttattgataa ccatttaacc ttcctttcta
    35221 tgcagatata atctattata acataaatcg cttacaaatc gtgtgggcat aaaaacacag
    35281 tctgcaaaaa aagccctgat aggcatgcct attagagcct cgaaaagaaa aatattgaat
    35341 caatctggtc gtacctcttg gatcggtttg acacgaccgc cgattctttt agcaaaagct
    35401 tcggattctt ttttgtcttt gaaaatgagc agattgtcta agtttttttc ccgagtgcga
    35461 cagccagttt tatcgatgta accgtgcatt actttaacga catacatggg gatcacctgc
    35521 ttttttcttt tcattatacg aactactcga cacaatacaa gaaaaatgct tagacggtct
    35581 ttattaagaa tttacatcat ccaaagaagc gtacgcttgg aataactgat ctaactccgg
    35641 attgactttg ctcagcttca ctaatcgttg cgaatcagaa agtaaaaaac agtgtttact
    35701 actgccagta gtttttaatt ttttgtcttc agttcccaca atttcgtagc taaaatccaa
    35761 ccgtgtcccc gtatactttt ggatagttgg atggatgctc actttttctc cgtaatggat
    35821 catttcttta tagctgcaat ttacttccag aacggggatg atgatcccag attcttcgat
    35881 ttttttatag ggaaacccta gatgtaccaa taaggctacc cgagcctctt caaaccagcg
    35941 gatataattg ctgtgatgaa taatccccat ttgatctgtt tcataataaa aaggttctcg
    36001 cacataacct gtaaatttct ccatgactca tgcctcgttt tccattgatt ttttacaaaa
    36061 ataattcatc catttcggaa gtgcttcgct gatttgtgtc ggcaaaacaa tatattgttc
    36121 ttttgccagc tggtctccaa tgaaactatg aagataaata gctgctgcaa tcgtttggtc
    36181 attttgagga aactgggcta aaaatcctgt gatcatccca gctaaagtgt cacccatgcc
    36241 gcccgttgcc atagcagcag aacctaaagg attggtgtag aagtgctggt gaccataaat
    36301 ttttgtctca tgacttttca aaacgagcac agcaccgatt tcctgttgct tctttttgtt
    36361 ttctttatcc cgttgttctt gtatcggtag agaactcaac cgttgccact ccatttgatg
    36421 aggtgtaagt acagtttgtt cgggataggg tagcaaaaga tgattagcag caagtaaact
    36481 taaagcagag ccatcaatca ccagccattg ttcttttgat tggttttcta gtacttgttt
    36541 gaaacgttcc aaactcttag aagaagtacc caatccggga ccaatcaaga gtacatctgc
    36601 ttgctttatt acggaaagaa actggtcagt atccgtccaa actacaatca ttgcttctgg
    36661 cagatgactg tgaagagcac tccgattttt ttcatcagtt actacagtcg tgagacccgc
    36721 tccgctgtgt acggcagcta aagcactcat aatgattgct ccgccatatt gttcattgcc
    36781 gccaatcaaa acgatacgtc caaatgttcc tttatgtgaa atttttggac gaggtgtgat
    36841 gactcttttc actagttgtt cgtttatcag catctaaaaa cctcctttta ctcattatag
    36901 cgtatatttt ttttagagaa aaacagataa gaaaaggaat tgtcagattt tttgaactat
    36961 ttttttctgt aatttgtggt atcatgaaca cgaagactta aataagtgga ggattaactt
    37021 tatgacaatt gattggcaaa aagaagtaga agcacgtaaa gaagacttgc ttgaagactt
    37081 gaaaaatctt ttacgtgtca acagcgagcg cgatgactca aaagtaacac cagatgcacc
    37141 atttggacct ggacctcgcg acgcattgaa acatatgtta gcttatggcg aacgtgatgg
    37201 atttaaagta aaaaatgtcg ataactatgc agggcatatt gatcttggcg aaggagacga
    37261 aacgctaggg atatttggac acatggatgt cgttcctgca ggagatggct gggacacaga
    37321 tccttatgaa ccagtaatca aggatggaaa gatctttgca cgcggatcaa gcgatgacaa
    37381 aggtccaagt atggcagctt actatgcgat gaagatcatt aaagaacttg acttgaaact
    37441 atcaaaaaaa gttcgcttcg tagtcggcag cgatgaagaa agcggctggg gcgatatggc
    37501 ttattatttc gaacatgaag aagaaccaga ttttggtttc tcaccagatg ctgaattccc
    37561 aatcatcaat ggtgaaaaag gaaatgtttc tttagcttta cgcttcaaag gcgacaatgc
    37621 aggagattat gtcttgaaat cttttgtttc cggacttcgc gaaaatatgg tgccaggaac
    37681 agcaactgca gcacttcaag taccaagtgc agatgcagct atcgcgatgg aagaagcatt
    37741 ttaccaattc atcgaagcaa atccagtaag cggaacgatt gaagcggaca atacgtatgt
    37801 aaaaatcgaa ttagttggta aaggcgcaca tggtgcaagc ccacaatctg gtatcaatgc
    37861 aggttctttc ttggcattgt tcttagataa ctatgaattc ctaggatctg ctaaacaatt
    37921 tatccatgta gcagctgctt atgtccatga agatttttat ggagaaaaac taggagtcgc
    37981 ttatgaagat gaaaaaatgg gcaaattgac aatgaatgct ggactatttg cttttgaaga
    38041 aaatggtaca gaggaagcga acttcatcaa tatgaatttc cgttttccaa aaggtgtaac
    38101 agtagacgga ttgcaaagtg acatcgaaca aacagtgggg caagaaggcg caacagttac
    38161 tcgaggtgct cgcgtaatgg aaccacatta cgtaccaatg gatgatccat tggtggctac
    38221 attattgcaa gtctatgaag accacactgg agaaaaaggc tacgaacaaa tcatcggtgg
    38281 cggaacttac ggacgtttgt tgaaacgtgg cgttgcttat ggagcgatgt tcccaggata
    38341 tactgataca atgcatcaag caaacgaatt tatgagtctt gatgacttgt tcagagcaac
    38401 agcaatctat gcagatgcca tctatcgttt ggcgaaataa ttaattaaaa agaggatcaa
    38461 gaattgcaaa ttatttttgc agtcttgatc ctttttttac tttctactgt ggtattcatg
    38521 ataaacatga tatagattca attcatattc tttcttagcg ttcgtgacga ctgtatccaa
    38581 aatcaaccct gttactaatg aaagaagtgc taaagtcatc aatccagtac ttaaaatcgc
    38641 agaagggatg cgtgtaataa agcttgtcag catatattcg cgaatcacag gaatccccgt
    38701 gaccaatcca aataaaaaga agaagatggt ccaaatccca aagaaaagca aaggcttata
    38761 atctttaaac attttaataa tcatcatgat cactttgaat ccgtcagaga atgtattcaa
    38821 ttttgattcg ctgccttcag gacgatcacg ataatcgatt gggatttcaa cgaacttgaa
    38881 ttttttatct aaagcatgga tcgtcaattc cgtttcgatt tgaaaaccag aactcataat
    38941 aggaaaactt ttgacaaaga tacgattgaa tcctcgatag ccggtcatga catcaagaat
    39001 ttttgtttta tacattctag taattgtatt tctaacaagg ttatttccaa aatcgtggaa
    39061 aggtctctta ttctcatcaa agtaggttcc atttgatagg cgatcaccaa tgaccatatc
    39121 tgcttcacca gaacgtaatt tctcgagcaa accatgtaca gcttctgcag gataagtatc
    39181 atcgccatct accattaaat aatagtcggc atcgatatca aagaacattt ggcggatcac
    39241 atttcctttt ccttgacgag gttctttttt tacgattgct ccaccttgaa cggccaattc
    39301 gtatgttcga tcggtcgaat tattatcata gacataaata tctgcttctg gtaattctcg
    39361 tttaaagtct gcaatgactg ttgaaattgt tgcttcctca ttgtaacaag gaatcagaac
    39421 agcaattttt tcttgttgtt ccatttttca ctctccttaa ctatagaaaa caaaagctaa
    39481 attaaaaata cctcataatc aaaggaaatg ctagtttttc ccgctaaata tcatttattt
    39541 aaaaagaaaa tactggaata tatgtttgga aagctctatc taaaaaacca cccactacaa
    39601 aagaaggaca tgatacctct cttttgaata gtgggtgcgt attcgttctc tcactttttt
    39661 gacgtattaa tctgttgcac ctttttttct tgaaatttct aatacggttc ctgtatgagc
    39721 atctgctaaa aattcataat aaacagtttc gccatcttct attcgagaaa gacctccccg
    39781 ataagcactc gaccgaacgg cgaatttcct aataggttcc ttttcaaaag agatccaaga
    39841 accttcgatt gcaccttctt ttagaaaaga tgacttgata ttttcaagta cttggtctgc
    39901 tgacaatact tttttgcgat gataccaaat cgttgaagct accccgctca ataatcctag
    39961 accgattcca actgctaacc cgcctttaaa atagcttagt tcgctttctt catacatgtg
    40021 gacatacctc cttcttctca cttgttactc cttgtgctta ttttaccaca ctctcatatt
    40081 ttctttgaaa taaataaccg ctaccagaaa aaataagcta taataaatac gatcggtctg
    40141 cagaaaaaat catattttat ccgcagatca atataagtct gagaggagtt tagtctgaaa
    40201 tttagacgaa tagcatatgg aagaaaaaac atttcaacga atcaaagagt taacagaatt
    40261 acaaggaaca agcggttttg aacaagatgt tcgcgcttat atggaaagtc atatggaacc
    40321 gctggtagat gagttacagt tagatggttt gggcggcatt tttggtctgc gccatcatga
    40381 agaagcggat gcaccccgtg taatggtcgc agcacatatg gatgaagtcg gattcatgct
    40441 gacacaaatc caagaaaacg ggctttttaa agtcgtacct ctaggcggct ggaatcctta
    40501 cgttgtttct gctcagcgtt ttacacttaa aacctctact ggtaagaatt atccatgtat
    40561 ttcttcttcc gttcccccac atttattgcg aggaacaagc ggacaaaaat cagtagaagt
    40621 aaccgatatt ttgttcgatg ctgggtttga atcaagagaa gaggcaatga gttacggtgt
    40681 ccttccagga gacacaatcg ttccttacgc tgaaacgatc aaaacagcca acggaaagaa
    40741 tattatcagt aaatcatggg acaaccgcta tggctgtaca atggtattag aagctttaga
    40801 agcgttgcaa aatgaaacat taggtcatac attgattgca ggcgcgaatg tccaggaaga
    40861 agtaggcttg cgtggttcta aagcttctgt caataaattc aagccagatc tgttctttgc
    40921 agtagactgc tctgcagcag atgatacagt gacgaaaaat ggcacattcg gacatttagg
    40981 agaaggtaca ttgatgcgta tccaagatcc aggtttgatc atgcttcctc gtttgcgcga
    41041 gtacttgctg gatatcgctg aaacaaacaa tatcccttat caatactttg tttcaaaagg
    41101 cggtacagat gcaggtgctg ctcatacaca aaacgaagga atcccaagta cagtgattgg
    41161 cgtagtggga cgttatatcc atacgcatca aacgatgttc agtattcgcg attttgaagc
    41221 tgcacgagaa atgttgattc aaacactgaa aggtttggat aaatcaacag taaatacgat
    41281 cgtatacgga aaataatgcg atagtgaaac tataaaatct ggcaaaagat tgctttttgc
    41341 cagatttttt ttataaaaag aggatcaatg tttgttagtt cgaaagaaag gtgtataatt
    41401 taattgaaaa atacataaac agaaagtaga ggacaaagaa tgattatccc aaatagttta
    41461 gaagaattag caggctacgt agaaactgga aagagtgtat ttttctttac tgccggctgg
    41521 tgcggagact gccgttttat caaaccgcaa atgcctgaaa ttgaaaatga cttttctgat
    41581 tggcaattta ttgaagtaga ccgtgacaag tacatagatg tagccgctga atggaacatt
    41641 tttggtatcc caagttttgt cgtgatccaa gacggaaaag aattaggtcg tctagtgaat
    41701 aaagatcgta aaacaaaaca ggaaatcgaa tcgttcctag aaagtgtaac aaaaggctga
    41761 catctgttag gaggggtcaa gatgaatcaa gaatataaga atattttagt aggtatcgac
    41821 ggtagtgaac aagcacttgc tgctttcaaa aaagcggtag aagtggctcg ccgtaataat
    41881 gggaaagtat atgtagcaaa cgtaatcgat cagcaatttt ataactttat gggctatgca
    41941 cctattgatc aaaatctagt cgatcagcaa actgaaacag ccaaggaaat gatcgaagaa
    42001 tgtaaagaat atgggaaatc tgttgattac acaaatatag aaggaattat tgcatatggt
    42061 tctgttcgtg aatccatggc agtcaaattg ccaaaaaaat atgagatcga tctaatcatg
    42121 gttgggcagt caggtctaaa tgcagtcgaa cgctttatga caggaagtgt agccagctac
    42181 gtgatacgtc attcaccttg tgatgtcttg atcgtttctg acgaagaaga acagccaagt
    42241 aattaagcaa gtggaacttg tacgaccttt ttaatcaatt aactaaaaca gtaaagggac
    42301 tgtgacaaaa gtcttgtcac agtcccttgt tacgaataaa tggtgttcca gaagaggctt
    42361 cttcggaaat aaagcatgaa aaaaatttca tgcagtgaat gcaatttttt gttaagataa
    42421 atctcagcaa aggataatgg aggaaagaac atgatttttg cttataacaa agcacacgtc
    42481 ggagacacct tgatggttat tatagccgac gataaaggaa cagaaaacac tgttgaacgc
    42541 aaatggaatg ttgctcggat caaagatgaa caaggtcaag ttgttgcttg gaactttttc
    42601 catatctccg atcatctaac aatcgaaggg aacggccaag taagcttaac agatgaggaa
    42661 ttagcgaaat tgaatcgatt gatcaaagaa gcaggattcg aagaacagct tgaagctgat
    42721 catgaaccga agatcgttgt cgggtacgta aaaacatgcg tcccacatcc tgattctgac
    42781 catttatcga ttactgagac agaagtagac aatggtacag tattgcaaat cgtttgcggt
    42841 gcacccaata tcgaagctgg acaaaaagtt gtcgttgcaa aaccaggagc tatgatgcca
    42901 gatggaatga tgatctggcc aggaactttg cgaggggtag atagctatgg aatgatctgt
    42961 tccgctcgtg aattgcattt gccaaatgct ccagcaaaaa aaggaatctt agtattgcct
    43021 gaggatgccg tagtcggaga agcatttcca aaataaagag gttgtgacaa gtctttgtca
    43081 caacctcttt tttattaatt ttcactattt tgattttgtt ttaatgccga ttgatcgatc
    43141 gtcaattcaa cagtagttgt tttttctttc gagccttcat agtaagtgat tttgacagaa
    43201 tctcccactt ttttcttata caaagcagat tgaagttcta caccagaaga aacttctttg
    43261 tcatcgatct tagtaatgac gtcgtattgt ttcaatccag ctttttcagc cggtgtagct
    43321 gtttggacat ttgtcacgat gacaccgtta gttacagatg aaggaatctt caagatttgt
    43381 tcttgttgct gagtagaaac ggcagataag tcgaccattg tgatacctag agctggacgt
    43441 gtcacttttc cgtctttttc cagttgattg atgatattca ctacatcgtt acttggaata
    43501 gcaaatccca ttccttctac gcttacatta gaagtagatt cagaagtact tgcgatctta
    43561 cttgagttga taccgataac ttgtccttcg atattaacta aaggaccacc agaatttcca
    43621 gggttgattg ctgcatctgt ttggatcgca ttgatattga ctgtttcgtt cgattcattc
    43681 gtacttgtca cttgtcggtt caaggaagaa atgattcctg aagtgacaga atttgcatat
    43741 tcagatccta gtggggaacc aatcgcaatc gcaggctcac caaccttcag agcacttgag
    43801 tcaccaaaag aggcaactgt ttcgactttg tctgaattga tcttcaacac cgctaaatct
    43861 gaataagcat ctgttccaac taattcagct tttaccttcg taccgtcttt catcaagact
    43921 tcaagacctt gctggccatc tactacgtga ttattcgtga ctacataagc agtattcccg
    43981 tcttttttgt agatcacgcc gcttccttca ctataagctt ccaaattact atcatctgag
    44041 ctgctacttt cttcttgctg cccgaatagt ccgccaaaac cgcttgattg gttttgactt
    44101 tgtaagttga taacagaaac gacagcgtct tgaactttat ctaccgcttt ggtgatatca
    44161 gaatctacat tgactttgac attttccaca actgtttcac cggcagaatt ctgattgccg
    44221 cttgtagcag tagaactatt gttgccagtg cccatcgctg cataaaaaat gccagctgtc
    44281 agtagtcctc caacgatccc tccaacaagc cccagaccta acttacgcca gaggctatta
    44341 tttttacttt ttttcatctt tggtgtcaca ttttttctat ccatgtgttc ctcctccaat
    44401 tacattcatt tatctactgt tagtatagtc ttatttgttg actttagtct actttgagac
    44461 tgtgaacttt ttatgaaaaa ctttaggaaa aatcattgtt ttcagatgaa aatatttgat
    44521 tttctttttc cacagatact gtgtaaaact acgcggatag gattggaaaa ataagggata
    44581 aaacatatcc acagcctgtg tataaagtgg ataaattctt ataaaacgta tgtttgccta
    44641 atgaatgtga tgaaataagg taaaataaca ctgttttctg tggataaacc tgtggatgtt
    44701 gtgcataact gttggggaaa tctttttaac aaaaatagcc aaaataaaca tatagacgaa
    44761 aaaattgatt ataataaaca aagtgagcat gaagaccaaa ggagagaaaa catgaatatc
    44821 aaaattatct cagtaggaaa attaaaagaa aaatacctga tccaaggtat caatgagtat
    44881 gtcaaacggc tgaatgccta tgcaaaaatc gaattgatcg aagttcctga cgaaaaagcc
    44941 ccggagaatt taagcgaagc gcaaatgaga caagtaaaag aaaaagaagg ggaacggatc
    45001 ttagcgaaaa tcaaagaaca agaatacgtc tatgccttag caattgaagg gaaaaatcct
    45061 acaagtgaat cttttgctaa acaaatcgac caattaggta tccaaggaaa aagccacctt
    45121 gtttttgtta tcggcggctc tttaggactc agcgaagccg tcatgaaaag aagcaatgct
    45181 cagatctctt ttggaaaaat gacgtatcca catcaattga tgcgtctgat ccttgtcgag
    45241 caaatctacc gtgccttccg gatcaatgcg ggggctccat accacaaata atgatatttt
    45301 ttaagagaaa aaattatccc tattttaaat aatagcaata ggtagtggta gggagaaatt
    45361 tataaataac ttttttattt gctttggtag ccaagtaagt tgcaaaagaa aaatagatac
    45421 tgttaaaaag ataatgtaga catagaaaca aatacgtaaa attttagtta gaataatggc
    45481 aaggagaaaa aacatgatag atgaaaaaaa gtgtttaaaa aatctattag aggatatgga
    45541 tgatattgaa gaaaactatc taaatggact gggaaaacaa atatatttca gatacttaag
    45601 ctatctaaaa atgaaataag acatagtaat tttttagctt ttttgtttgc tccaaatgaa
    45661 acccacaatt tatctgatga gttttttaaa atgtttttga aaaggtatat agattctaat
    45721 gatgatacca aagctgctat caattatttt gatgctttac ttaatagcta tgaagattta
    45781 attgtttaca gagaaaataa gaatattgat attttattgg tatcggaaaa aaataaaata
    45841 gtggtgtgca tcgaaaataa aattctgtct tcggagtctg gagggcaact taataaatac
    45901 caaatatata tagaacgcaa ttattctaac tataaaaaaa tttttgtttt tttaactcca
    45961 gatggaaatg aacccacaaa tcctagttgg ggcataatta cttacaagaa tatcgttgaa
    46021 gagagtgtaa aatattttgt gtaaatagaa aaaaggaagt cccttctgta gaatagagtt
    46081 accacaacac attcacagaa aagaggactt ccatatgaac gattttacta cagaaattat
    46141 ggaaatacta atcaataaag gtgatttgga tgatttgttt cgtcgtcacc tagaattggc
    46201 tattaacgct ttattacaag ctgaattaac ggtatttctt gactatgaaa agtatgatag
    46261 agctggattt aattcaggta attcccgtaa tgggaattat tcgcgctctt ttaaaacaga
    46321 gtacggtgaa ttgaatttag taatacctag agataggaat ggagactttt ctcaacaaac
    46381 tttacctgct tataaaagaa ccaatgactc tttagaaacc actattattc agctagttca
    46441 aaaaggaatt actatgtccg aaatctctga tctaatcgaa aaaatgtatg gtcattatta
    46501 caaaccacaa actatttcaa atatgagtaa aattgtgtct gaagatgttt cggcatttaa
    46561 agaaagaact ttagaagcta aatactcagt catttttatg gatgctactc atattccctt
    46621 aaaaagacaa accgtatcaa aagaagctgt ctatatagta attggtatca ggttggatgg
    46681 aactaaagag gttctaggat ttactatagc tccaactgaa tctgcttatg tttggaaaga
    46741 gattcttcaa gatctaaaag accgtggttt agaagaggtt ttgttagtcg taacagatgg
    46801 tttaagtggt attgacgata gtattcatag tgtttatcca aatgctcaat ttcaacaatg
    46861 ttgtgtccat atatctagaa atatcgctca taaggttcgt gttagtgatc gacaagaaat
    46921 ctgtagcgat ttcaaattag ttta
//
LOCUS       DADVXV010000013        44769 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.013, whole genome shotgun sequence.
ACCESSION   DADVXV010000013 DADVXV010000000
VERSION     DADVXV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.013"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            158..550
                     /locus_tag="KB969_000678"
     CDS             158..550
                     /locus_tag="KB969_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6868690.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            578..1918
                     /gene="glnA"
                     /locus_tag="KB969_000679"
     CDS             578..1918
                     /gene="glnA"
                     /locus_tag="KB969_000679"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBB6868691.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3111..4721
                     /locus_tag="KB969_000680"
     CDS             3111..4721
                     /locus_tag="KB969_000680"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBB6868692.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5013..5882
                     /locus_tag="KB969_000681"
     CDS             5013..5882
                     /locus_tag="KB969_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBB6868693.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6047..7318
                     /locus_tag="KB969_000682"
     CDS             6047..7318
                     /locus_tag="KB969_000682"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6868694.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7315..8610
                     /gene="rho"
                     /locus_tag="KB969_000683"
     CDS             7315..8610
                     /gene="rho"
                     /locus_tag="KB969_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBB6868695.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8709..8972
                     /locus_tag="KB969_000684"
     CDS             8709..8972
                     /locus_tag="KB969_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBB6868696.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9417..9866
                     /locus_tag="KB969_000685"
     CDS             9417..9866
                     /locus_tag="KB969_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6868697.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9923..11341
                     /locus_tag="KB969_000686"
     CDS             9923..11341
                     /locus_tag="KB969_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6868698.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11341..12201
                     /locus_tag="KB969_000687"
     CDS             11341..12201
                     /locus_tag="KB969_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBB6868699.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12375..13148
                     /locus_tag="KB969_000688"
     CDS             12375..13148
                     /locus_tag="KB969_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6868700.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13295..13660
                     /locus_tag="KB969_000689"
     CDS             13295..13660
                     /locus_tag="KB969_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBB6868701.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13808..15016)
                     /locus_tag="KB969_000690"
     CDS             complement(13808..15016)
                     /locus_tag="KB969_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6868702.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15035..15313)
                     /locus_tag="KB969_000691"
     CDS             complement(15035..15313)
                     /locus_tag="KB969_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868703.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15467..16162
                     /locus_tag="KB969_000692"
     CDS             15467..16162
                     /locus_tag="KB969_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6868704.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16604..17401)
                     /locus_tag="KB969_000693"
     CDS             complement(16604..17401)
                     /locus_tag="KB969_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBB6868705.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17398..18582)
                     /locus_tag="KB969_000694"
     CDS             complement(17398..18582)
                     /locus_tag="KB969_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBB6868706.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18607..19854)
                     /locus_tag="KB969_000695"
     CDS             complement(18607..19854)
                     /locus_tag="KB969_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBB6868707.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20069..21814
                     /gene="dnaX"
                     /locus_tag="KB969_000696"
     CDS             20069..21814
                     /gene="dnaX"
                     /locus_tag="KB969_000696"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBB6868708.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21834..22148
                     /locus_tag="KB969_000697"
     CDS             21834..22148
                     /locus_tag="KB969_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBB6868709.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22173..22769
                     /gene="recR"
                     /locus_tag="KB969_000698"
     CDS             22173..22769
                     /gene="recR"
                     /locus_tag="KB969_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBB6868710.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22833..23477
                     /locus_tag="KB969_000699"
     CDS             22833..23477
                     /locus_tag="KB969_000699"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBB6868711.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23492..23821
                     /locus_tag="KB969_000700"
     CDS             23492..23821
                     /locus_tag="KB969_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBB6868712.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23835..24773
                     /gene="holB"
                     /locus_tag="KB969_000701"
     CDS             23835..24773
                     /gene="holB"
                     /locus_tag="KB969_000701"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBB6868713.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24809..25633
                     /locus_tag="KB969_000702"
     CDS             24809..25633
                     /locus_tag="KB969_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBB6868714.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25626..25973
                     /locus_tag="KB969_000703"
     CDS             25626..25973
                     /locus_tag="KB969_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBB6868715.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26042..26914
                     /gene="rsmI"
                     /locus_tag="KB969_000704"
     CDS             26042..26914
                     /gene="rsmI"
                     /locus_tag="KB969_000704"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBB6868716.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27023..28144
                     /gene="dinB"
                     /locus_tag="KB969_000705"
     CDS             27023..28144
                     /gene="dinB"
                     /locus_tag="KB969_000705"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBB6868717.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28198..28800)
                     /gene="nrdG"
                     /locus_tag="KB969_000706"
     CDS             complement(28198..28800)
                     /gene="nrdG"
                     /locus_tag="KB969_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBB6868718.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29115..31304)
                     /gene="nrdD"
                     /locus_tag="KB969_000707"
     CDS             complement(29115..31304)
                     /gene="nrdD"
                     /locus_tag="KB969_000707"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBB6868719.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31603..32397
                     /locus_tag="KB969_000708"
     CDS             31603..32397
                     /locus_tag="KB969_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868720.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32387..34429
                     /locus_tag="KB969_000709"
     CDS             32387..34429
                     /locus_tag="KB969_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6868721.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34710..34859
                     /locus_tag="KB969_000710"
     CDS             34710..34859
                     /locus_tag="KB969_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBB6868722.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34870..36384
                     /gene="dltA"
                     /locus_tag="KB969_000711"
     CDS             34870..36384
                     /gene="dltA"
                     /locus_tag="KB969_000711"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBB6868723.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36381..37586
                     /gene="dltB"
                     /locus_tag="KB969_000712"
     CDS             36381..37586
                     /gene="dltB"
                     /locus_tag="KB969_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBB6868724.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37631..37864
                     /gene="dltC"
                     /locus_tag="KB969_000713"
     CDS             37631..37864
                     /gene="dltC"
                     /locus_tag="KB969_000713"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBB6868725.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37867..39135
                     /gene="dltD"
                     /locus_tag="KB969_000714"
     CDS             37867..39135
                     /gene="dltD"
                     /locus_tag="KB969_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBB6868726.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39276..40358
                     /locus_tag="KB969_000715"
     CDS             39276..40358
                     /locus_tag="KB969_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBB6868727.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40358..41161
                     /locus_tag="KB969_000716"
     CDS             40358..41161
                     /locus_tag="KB969_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6868728.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41231..41971
                     /locus_tag="KB969_000717"
     CDS             41231..41971
                     /locus_tag="KB969_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6868729.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            41982..42986
                     /locus_tag="KB969_000718"
     CDS             41982..42986
                     /locus_tag="KB969_000718"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBB6868730.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43031..44728)
                     /locus_tag="KB969_000719"
     CDS             complement(43031..44728)
                     /locus_tag="KB969_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868731.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14371 a         7820 c         9331 g        13247 t
ORIGIN      
        1 gtacgaaaat caactagata ccttttttgt gttcttattt ttttgttatt ttataaaaaa
       61 tagagatctc atgttagaaa acctaacata tgcagttgac aatatttttt ttaattggta
      121 cactttagcc aacttataaa acgaaagggg acgtctgatg ggagaaaagg aattgcgccg
      181 atctatgtcc gtatttccaa ttggtacagt tatgaagctg actgatttgt ctgctcggca
      241 aattcgctat tatgaagaac aagatttagt tcatccggaa cgaagcgaag gaaaccgacg
      301 tatgtattcg ctgaatgata ttgatatgtt gcttgagatt aaagactatc tttcagaggg
      361 attgaatatg gctgggatca aacgtgtata cgaaatggca caggcgaaaa aacaagaagc
      421 aaaaaacaag aagccgttga cagatcatga cgttcgacaa atttttcgtg atgagatttt
      481 ggcgcaaggt gggttaagca aaacaggtca ttatcagtcg caaggattgc aaagacaatt
      541 ctttgactga ataaattaaa aaaggaagag ggataccatg gtaaagaaac agataacagg
      601 tgaagaaatc aaacgaatca ttgaggaaga aaacgtacga tttttacgat tgatgttcac
      661 agacatctta ggtacgatca aaaatgtaga agttccagtg agccagatcg acaaagtatt
      721 agaaaataaa atgatgtttg acggttcttc gattgaagga tttgttcgaa ttgaagaaag
      781 cgatatgtat ttgtatccag atctctccac ttggatgatc ttcccgtggg aaagtgctca
      841 tggaaaagtt gctcgtttaa tttgtgatat ctataatccg gatgggacac catttgccgg
      901 cgatcctcgc gggaatttga aacgagcatt gaaagatatg cgcgaccttg gttttacctc
      961 tttcaattta ggacctgaac cagaattctt cttatttaaa ttagacgaag acggtgggat
     1021 cacaacgacc ttgaatgata aaggtggtta ttttgatttt gcaccaacag atttaggtga
     1081 aaattgccgc cgtgacatcg tgttggaatt agaaagtcta ggctttgaag tggaagcttc
     1141 acatcatgaa gtagcgccag gacagcatga aattgacttt aaatatgcag atgtggtaga
     1201 tgcttgtgat aatatccaaa ccttcaagct cgttgtcaaa acgattgcac gcaagcatgg
     1261 acttcacgcg actttcatgc cgaaaccgtt atttgggatc aatggttctg gtatgcattg
     1321 caatatgtct ttgttcaatg atgaaggaaa tgttttctat gataaagacg gtgaattgga
     1381 actaagtgaa acagcttatc atttcttagg tggtttgctg aaacatgctc gtgcctacac
     1441 agccgtttgc aatccaacag tcaattctta taaacgtctc gttccaggtt atgaagcgcc
     1501 tgtttatgtc gcatggagtg gccgtaatcg ttcgccatta gtacgtgtac cagaatctcg
     1561 cggtttatcc acacgtttgg aattgcggtc agttgatcca tctgcaaacc catacttggc
     1621 aatggcagta ttgttgcaag caggactaga cggtatccgt aatcagatca caccgccagc
     1681 agctgttgac cgtaacattt atgtaatgga tgaggaagaa agagaagctg cacatatcca
     1741 ggacttacct tcaactatcc ataatgctat caaagaattg cgtaaggata atgtaatgat
     1801 tgacgcatta ggacaacata tcttctcaaa ttttgttgaa gcaaaacgtc tcgaatgggc
     1861 ggcattcaga caaactgttt ccgagtggga aagagaacaa tatctagaac tttattaaaa
     1921 caggaatacc gtgaattaga ggctgtgaaa tcagcgtttt gacctgagta ttagagaaac
     1981 taacggaaaa atagttcctc atattttgcc gttttttgag ctaataccga gggtcagctg
     2041 attgaacacc gtttagtgga gaggttgtga aaaagctgcc ctgcaacaag taataagaat
     2101 agccaagcaa aaacagcttt tcttgttttt gaattggctg aacttattac cgcagatgca
     2161 agcttttgaa caccgtttac caagaggttt tgaaaaagac gtttagtttc gagtattaag
     2221 aaaaattttg tgaaaatggc tttctacatt tttgcataaa tttggcttaa taccgagaaa
     2281 ctggcttttg aataccgttt atccagaggt tgtgagccta ccatttaact ccgaatcaca
     2341 agaaataatt tcaaaaacag cttctcatgt ttgatggata ttgtgacttg tgaccgagga
     2401 gttggcagga gaacaccgtt tatttagaaa taaggaggca cgacttttgt cgcatctcct
     2461 tattttttac ttatgtgatt cgttaccttc aatgaatccc tacaaggcac ttttgttgaa
     2521 aaaaaggtca tctttgaaaa aattagtgga attgttttgt ttttgatatt atttaataga
     2581 aaagatatgc caaaaatccg agaactgtgg actacgtttt ttacgtaaag gaggtaaata
     2641 agggtgaaag aaaaagattg tttctacgat aagctatata aactgttgct gcaagtagga
     2701 aaaagtagtt ctttgttagg tgggatatta tctatcataa tgtttgtttt atttttttat
     2761 ctattatttc acttaaaatt tttcagtaac gattttctga tttgcttagg tttaacgtta
     2821 gctatgttta tatcaagctt attatgtggg ttaaattttt tttgcactca taaaggactt
     2881 aagaaataat ttctcaaagg atatcgaaaa agaaaaaatt gtaagcggat agtattcatt
     2941 tgagtacttg actttccctt agtcagcttg tattatacac cttgggcacc cttttagagg
     3001 gtcagaagtt tacagaaatt tcggctccct attcttattg aagaataggg agctttgttt
     3061 attgtctgag acttttcctg cacataaatt aaaaaggagt ttttgaactt atgacaaaat
     3121 atatttttgt gaccggcggt gtcgtttcat caatcggaaa agggattgtt gcagcttctt
     3181 taggacgctt attgaaaaac cgcggcttaa aagtaactat ccaaaaattt gatccataca
     3241 tcaacgtgga tccggggacg atgagcccat atcagcacgg agaagtattc gtaacagatg
     3301 atggtgctga aacagatttg gatctgggcc actacgaacg ttttattgac atcaatttga
     3361 acaaatactc caacgtgacg acaggaaaaa tctattctga agttttgcgt aaagaacgta
     3421 agggcgaata cttgggagca actgttcaag ttattcctca tattacaaat gagatcaaag
     3481 aaaaaatcat gcgagcagct aaaatgactg attcagatgt gatcattaca gaagtagggg
     3541 gaacagtagg ggatatagaa tctttgccat tccttgaagc acttcgtcaa atgaaagcag
     3601 atgtcggtac agataatgtt atgtatatcc atacaacatt gattccttac ttgaaagctg
     3661 ctggagaaat gaaaactaaa ccaacgcagc acagtgtaaa agagctacgt ggtttaggta
     3721 tccaaccgaa tattttggtg gtacgtacag agcaacctgt ttctcaaagc gtgaaaaaca
     3781 aattggcaca attttgtgat gtcgaaccag aagcagttat cgagtcgcca gatgtagata
     3841 cactttactc catcccatta gttttacaag cacaaggaat ggatcaaatt gtttgcgacc
     3901 atttaaaact agatacacca gaagcagaca tgacagaatg gaaagaatta gaagaacgtg
     3961 tcttgaactt gaagaaaaaa gtacggattg cgcttgtcgg taaatatgtc gagttaccag
     4021 atgcatatat ctcagtagtt gaagcattga aacattctgg tttcgcctat aattcagaca
     4081 tcgagatcga ttggatcaaa gcacaagaat taacgagaga aaatgtagaa gaacgtttga
     4141 aagacgcaga tggaatcttg gttcctggtg gatttggtga tcgcggagta gaagggaaaa
     4201 tcgaagcgat tcgttatgct cgcgaaaatg acgttccgtt tttaggtatt tgtcttggta
     4261 tgcagatggc ttgtgtcgaa tttgcacgta acgtcgttgg attagaagat gcgtcatcag
     4321 ctgaaacgaa tccagataca gcaaacaata ttattgattt aatggctgat caggaaaaca
     4381 tcgagaattt gggtggaact ttacgccttg gattataccc atgtaaaatc aaaaaaggaa
     4441 cgaagacggc tgaagcatat gatggagccg atgttgtgca agaacgtcac cgtcaccgct
     4501 atgagttcaa taacaaatat cgtcaattgt ttgaagaaca agggctagtc ttttcaggtg
     4561 tctcaccaga taaccgttta gtagaaatcg tagagctgcc agagaaaaaa ttctttgtgg
     4621 gatgccaatt ccacccagaa ttgatttctc gtccaaatcg cccgcaaaaa ttaatcaaag
     4681 catttgtcgg agcatcatta gcagatcacg aaacaaaata atttttgaac ttgatagaaa
     4741 gagaaaagta gcaagagaag gggataagca attttcttgt cacttttctc tttttctgat
     4801 ttgttattat ttgtaggaaa aaagatagaa agcaaaagac ttttttcgat taaagcgcta
     4861 ttggatattt tattttttgc aaaaaacttc ttgaaaattt tcattttcat tgattttagt
     4921 agaaaactac cgaaatgttt ggtaaaatag ggtcgttggt taagaattgt cttaacaaat
     4981 ttagttttac aaaacttagg aggaatttta ttatgccagt agtatcagga gctgaatttt
     5041 taaaagctgc tcgtaaaggc ggttacgctg tcggcggatt caacacaaac aacttggaat
     5101 ggactcaagc aatccttgaa gcggctgaag caaaacaagc accagtactt atccaaacat
     5161 caatgggtgc agctaaatac atgggtggtt acaaaatctg taaagattta atcactgatt
     5221 tagttgaagc aatgaacatc actgttccag ttgctatcca cttagaccat ggtgattacg
     5281 aagctgcttt ggaatgtatc gaattaggct atacttcagt aatgttcgat ggttcacatc
     5341 taccatttga agaaaacttg aaattagcta aagacgttgt tgaaaaagca catgcaaaag
     5401 gtatctcagt tgaatgtgaa gttggttcaa tcggcggaga agaagacgga atcatcggta
     5461 acggcgaatt agctgatatt gaagaatgca aacaaatggt tgctacaggt atcgactact
     5521 tagcttgcgg tatcggtaac atccatggtc aatatccaga aaactggaaa ggattagctt
     5581 ttgaccactt acaagcaatt gctgatgctg taggtccaga catgccttta gtattacatg
     5641 gcggatcagg tattcctcaa gatcaaatcg aaaaagctat ctcaatgggt atctcaaaag
     5701 taaatgttaa cactgaattc caattatcat ttgctgcagc tactcgtaaa tatatcgaag
     5761 ctggtaaaga taaagaaggt aaaggattcg accctcgtaa attattagct ccaggtaaag
     5821 cagcaatcgt tgaagatgct aaatctcata tcgactggtt cggttcagct aacaaagcgt
     5881 aagcatccac ataacagata cgatatatag gaatggagaa cgacttttga agtcgctctc
     5941 cattcttttt tacttaaaac ggcagaccat gctcgtttct tttttttatc tatgataaaa
     6001 tacaagcata tccatgaaaa aagattaata aacaaggtgg aaacagatga aaaaaatcgt
     6061 aatcaaagga aaccgacctt tagctggtga agtaacgatc agcggtgcaa aaaatagtgc
     6121 agtcgcattg attccagctg caatcttagc tgattcccca gtgatcttgg aaggtgtgcc
     6181 ggacatacaa gatgttcatt cattaattga aattttagag atcatgggcg caactgtcca
     6241 tttttccaac aacatactag aaatcgatcc tcgagaagtc gtatcgattc cgatgccgca
     6301 cggaaaaatc aatagtttgc gtgcttctta ttattttatg ggaacactgc ttggtaaatt
     6361 tggcgaagcg gtagtaggcc tgccaggtgg ctgttattta ggccctagac cgattgacct
     6421 acacgtcaaa ggatttgaag ctctaggtgc tgaagtgaca aatgaacatg gtgccatgta
     6481 tttacggaca gaaaataaag gattgcgtgg caatcggatt ttcatggacg tggtttcagt
     6541 cggagcaacg atcaatgtga tgttagctgc tgtaaaagca aaaggacaga cagtaattga
     6601 aaacgctgca cgagaaccgg aaatcataga tgtggcaact ttactgaata atatgggggc
     6661 aaaagttcga ggagcgggta cagatgtgat ccgtatcgaa ggagtcgaaa cattacatgg
     6721 ctgtcggcat ttcatgattc ctgaccgcat cgaagcagga acctatctag cattagcagc
     6781 tgcagtagga aatggtatca aagtgaaaaa tgtgatcttt gaacatttgg aaagctttat
     6841 agcaaaattg caggaaattg gtgtccatat gaaaatcagc gaagatgaaa tcgaagttta
     6901 cccctcgaaa gaattaaaac ccgcaaacat catgacctat ccttatccag gatttgccac
     6961 agatctgcag cagccactta ctgcgttact attgatgact acaggcactt cagaaatcat
     7021 cgatacgatc tatgcgaaac gtgtgaacca tgtgccggaa ctagcacgaa tgggcgctga
     7081 tattaccgtg gaaggaaata tgatcatcgt gaatggtcca aataaacttc acggcacaga
     7141 agtcgtggct tctgatcttc gggcaggtgc ttgtttagtg attgctggac tattggcaga
     7201 agggacaacg acgatttaca atgtagatta tatcttacgc ggttatgatc atattatcga
     7261 gaaactaaca gccttagggg catcaattga aatgatagag gaagtgggag ctgaatgagc
     7321 gattatttga caatggcaga actagagaac aaaacgttaa aagaagttta tagttatgcc
     7381 aaagaattta aaattcctta ttacagtaag atgaataaaa aggaattatc tctagctgtg
     7441 attcgtgcac aagcagagaa acaaggattt tattatatgg aaggaatatt ggatatcgtt
     7501 ggtcaagatg gttacggttt tttacggcca atcaattatg gaccaagtgc agaagatatc
     7561 tatatttctg cctcacaaat cagacgattc agtttgagaa atggggacaa agtggcagga
     7621 aaagcccgtc cacctaaaga atcggaacgt tattatggtt tgatgcacgt ggaaagcgtt
     7681 aatggaaaag atccggaaga agcaaaagaa cgtccgcatt ttccagcctt aacacctctt
     7741 tatccgcaaa gacagcttca actggaaaca acaccgcaaa gactatctac ccgaatgatc
     7801 gatatctttt ctccaatcgg ttttggtcag cgtggattga tcgtcgcacc gccaaaagca
     7861 gggaaaactt ctgtattaaa agaaatcgca aatggtatca ccgaaaacta tccggaagta
     7921 gaattaatcg ttctactgat tgatgaacga ccggaagaag taacggatct agaacgaagc
     7981 gtgaaaggcg acgtggtatc ttctacattt gatctgcagc cgcaaaacca tactcgagtt
     8041 tctgaattag tattggaacg cgcaatgcgt ttagtcgaag ataaacgaga tgtcgttatc
     8101 ttgatggata gtattactag acttgctcgg gcctataact tagtcgttcc accaagcgga
     8161 cgtacattga gtggcgggat tgacccagcc gcattgtata aacctaagaa atttttcggg
     8221 gcagcaagaa acatcgaaga aggtggcagt ttgacgattt tagcgaccgc tttagtcgat
     8281 acaggaagcc gtatggatga cgtgatctat gaagaattca aaggaactgg aaatctagaa
     8341 ttacaacttt cacgtgaatt atctgaacgt cggatcttcc cagccatcga tatcaaaaaa
     8401 tcaggtaccc gaaaagaaga attattgatg ccaagtgaag aattagaaga aatttggaaa
     8461 cttcgaaaaa atatgactgg agattcatta gaatatacgg aacaactgat ccgctttttg
     8521 cgtaaaacaa aaaacaatca gcaatttttc aaagaatttc aagatgtctc ctttggtaaa
     8581 aaaaatccga ccagaaatct gaaaagataa ttgcaacctt gactgaaaca tgttaagatg
     8641 ttaatgttgt aaatcgacaa atcaactctg gttcagcaaa tggagcaggg caaaggagcg
     8701 aaaaaatcat gaaagaaaac atccatccag attaccaccc agtagtattc atggattcaa
     8761 caactggttt caaattcttg tcaggttcaa caaaaacttc acaagaaaca gttgaatggg
     8821 aagacggtaa tacataccca gtcatccgtg tcgaagtaac ttctgactca catccattct
     8881 acactggacg tcaaaaattc acacaagcag acggacgtgt ggaccgtttc aacaaaaaat
     8941 acggtctcaa agacgcaaac gctgcggaat aataaaaacg ctgataactc aacgtttagc
     9001 agactatctg atagggatag tctgtttttt tatgtttttt gccaatttaa aacttcgttt
     9061 gatgctgaaa aagtcgtagg atcataatgc acaaaacaat gaaaaactag tatatagttt
     9121 taattatcca cttgataaaa acaccttata ttaacgaaat gaagaggggt tatttcgaag
     9181 taaaaaacca tttacctaaa attagaagct aagctttcct ttcaaggaag gctttttgtt
     9241 ttgttataga cttgcgattg tttgtgagct agatcgttca ttttaatgac ttatacacgc
     9301 ggatgatggg tctttttcct ctgttcattc ataatattga acggtacagc tagcgatgct
     9361 atactgacct cagttccaag aaaacgttaa cattttttgt gggggagagg ttttttatga
     9421 ggtttgatca attgatcgca gaagaactga ttgttttcga tccatcgata gattcaaaag
     9481 gatcattatt tgagcgaata ggggatgtgt tgaaaaaaac aaataaggta agaaatgttc
     9541 aaaaagtcgt taaggcacta ttcaaacgag aggaggagat ctccacagga atagaagatg
     9601 gatttgggat tccccatgca aaaagcaaat atgtgacaaa accagcactg tgtttttttc
     9661 atacagccaa attaacggac tatagcggga tagatgaaat gccaattgaa tatatttttg
     9721 ccatcgtagt tcctgaaaaa tcagcagata tgcatctaga gattctcagc acactctcca
     9781 gacgattgat gaatgcagat tttagaaagg gaataaaaga agccactacg ccagcagata
     9841 tcatcagaca gattagtcaa gaatgaaaat agtagagtct ttgtccgagt atcgatagtg
     9901 aagaaaaagg aggaaaataa tcatgaaaat cgttggtgta actgcttgcc cgactggaat
     9961 tgctcatact tatatgtcgg cagaaaaatt agaagtaaca gcaagaaatc taaaccatca
    10021 agcaaaattc gaaacacaag gtgtaaaaac agaaaatcag ttatctgaac aagaaatcaa
    10081 agaggcagat gcaatcattc ttgcagtaga taaagaaatc gaattggacc gatttgccgg
    10141 gaaaaaagta aagcgtgtct ctacaagccg agcaatcaaa gaaccgcaag tagtaataga
    10201 cgaagcattg agagatattg gcgtattcgt tgtgtctaat gaaaaagaac cagctgcaaa
    10261 tgagaaaaag ccgacaatct ataatcattt catgaatggt gtgaattaca tgcttccatt
    10321 tgtgatcgca ggcggaatca tcatcgcact gagttttgcc tttgggatta cagcggctga
    10381 tcccaactca gcagactata atgtgttagc agctgcattt tcaaggatcg gaggagatac
    10441 agcgtttgcc atgatggttc ctgcgttagg cgcggggatt gctacatcga ttgctggaaa
    10501 agcaggtttt gccccaggaa ttgttgccgg attactggcc tctacaggtg gttcaggttt
    10561 tcttggcgga atgattggtg gcgtgctagc agggtatatc tgtgattttc tggcaaataa
    10621 aattagcgta aaaaaagaat tttctgctat ttatcagctg attgtcgtcc cctttttatc
    10681 gatcttaatt attgggcttt tgatggtatt tgtgattgaa caaccgatca catgggtgtt
    10741 ggatgctttg acaaattggc tgaatagctt gggaaataca tccgggctat tgttcggatt
    10801 acttatcggg atcatgatgg cagctgatat gggtgggccg atcaataaat cgacttcgac
    10861 tttctcgatc ggtttgatgt cagctggagt aaatgcaccg attgctgctt gtatggctgc
    10921 aggaatgaca cctcccctag gtattgcttt agccacttta ttattcaaac ataaatttac
    10981 caaagaagaa cggacttcag gtcaatcatg ctggatttta ggcgcttcgt atattacaga
    11041 aggtgctata ccgtttgcgg tatctgaccc gatccgcgtg atacctagtt tgatgacagg
    11101 ttcagcagtc gctgcaggga tttccatggc agtaggagtt acttcaatgg cacctcatgg
    11161 agggatttgg gtgatgctaa ttccaaatgt tatgaacaat ttacctatgt atgtcttggc
    11221 aattgcatca ggtacagtca ctacagcctt tatgcttgga ctattgaaaa aaacagtgaa
    11281 agagaaaaaa caagacaagt ggacgaaaaa tgaaaatcta acaaatgagg tggaagcgta
    11341 atgttatata caatgaaaga gttattgaaa gtggctaaag agaatcaatt tgcagtacca
    11401 gccttcaata tttgcagcta tgatatgatg aaagcaatca tcgaagaagc agagagatta
    11461 gaagcaccag taatcttaga aattcatcct gatgaaatcg cctatttaag tgatgagttt
    11521 gttgcggcag taagagccta tgcttataca agtaaactgc cgatcgttat ccacttggat
    11581 catggcggta cgatagaaga tgtcttacgg gcgattcgaa acggctattc ttccgtgatg
    11641 atcgatgcgt ctttgaaatc attcgacgac aatgtacaga ttacgaaaaa agtggttgcg
    11701 ttagctcatg cggtaaatgt ctcagtggag gctgagcttg gaacgattgg gaataatggt
    11761 tctgctgaag gaggtgctga aacaatcatt tatacagatc ctgatcaagc gaagattttt
    11821 gtgaaagaaa caggaatcga tacacttgct gtagcaattg gaacagcgca tggcttgtat
    11881 ccgaaaaaca gaactccaaa attaaatatc gacttactga aagaattgaa ccaacaaatc
    11941 gatcttccat ttgttttaca tggcggttca ggtaatccgg acgcagaagt cagcgaagca
    12001 gtaaaatacg gagttgccaa agtgaatttg agctcagatc ttaaaagcgt ctttttcaat
    12061 gctttgagag aaatattgag tgaaaatcca tcgatgtacg agccgaatgc aatttatcca
    12121 gcagctaata aaaaggtaca agaagtggtc aaacataaaa tggaaatttt gaacacagta
    12181 ggcaaggcta gtttatacta aaaataaaaa tgtgtggtca agagggtatg acaatagtct
    12241 tgtcataccc tcttaaccac acacgatgtt cagaagtagt tttttcgaaa aatttcttct
    12301 tatttctcga agccaatcac ttctgtcaca acctcttttt tcctgttact atataaagta
    12361 aatggggtga ttttatgttg aatgaagtgg agaatagaca gcaggagatt gtgaattatc
    12421 taaaaaacaa ccaatttgca agagtcaccg atttgatcga gttagtaaat tatagcgaag
    12481 ccacgattaa acgtgacctt gtttttctgg aaaaaagtgg attgatccgt agagttcgcg
    12541 gtggcgccat gcttattgac aatcgaaaaa ttgacgtgcc ttacctgatg aagatcacca
    12601 aattagaaga agaaacagaa aaacgtaaga ttgcagatac agcttcttct ttgattcgag
    12661 atgatatggt cttattcttg gattccagta caacctcttt acacttagtc agaaacctag
    12721 caagatttga tggtttgcag atcattacga atggcatcgt cacagctgct atgttgagtg
    12781 aatatacaac ggcaaaagta tctgtattgg gaggggcaat tgttccgaaa cgagcaacaa
    12841 tcaacggttc aaaagcctat aacgatgcat tgtcatatta tgcggattta gcgataatga
    12901 gttgtcgcgg gctagatttc agccaaggag taacagaaac tcatgaagga gaggcaatgg
    12961 tcaaaaaagc ttttagaaaa caatcagacc ggcttgccgt tttagttaca cagcaaaaaa
    13021 ttgcacataa attcatgcat caagccattg cttttcatga aatcgattat ctggtgacaa
    13081 gtaaagaact gacaaaagaa cagtatgcga aagtaaagga acaccatatc gaatgtctgt
    13141 acggataaat tattacgtga atgttctaag tggcttcctc atttttagat aggaccttat
    13201 ctttgctcgc ttctctcagc cgatggtata ataatgaaaa ggttatcttg ttagataatc
    13261 ttactttttt atccaggaga aaggagtgca gaaaatgaaa catgtgaagg cgttggtagt
    13321 gaaggcaatc atgatctggg cgattctgtg ggtcgtgctg acaggtttat acggtgttag
    13381 ctttatggat tcaacgattg ttggggtaat tattgtagtc atgatctatg tgctagggga
    13441 tctgttgatc ttacgtaaag tagggaacat cgcagcgacg atcgcagatg ctggttcagc
    13501 tgcagttatc ttgtggctct atctatattt tatgaatgat acagtcgata tttggatgaa
    13561 agtattgatt cctgctctat tgatcggtgt ggcagaatgg ttcttccaca agtggttgct
    13621 aagtcaaggc atcgtaccag atgaacggaa aatggaataa atcaacagtt aaactattct
    13681 tatcgataaa tgaaagcttt aaaaataaat agatgtttaa ttaagaataa tcataaacta
    13741 tttttactca aaaaaccgct cagattattt tcagatctga acggtttttt ttatctattc
    13801 atcaagatca aatttcattt ttcaatgatt caatcaattc gccctctgct tcatgactat
    13861 gttttcggcc attaacaaga tagagtgctg tacatatcaa tggaatgact ccggcaatca
    13921 catacaatcc tctaaatgaa gtaagagatt ttagcatccc catcaaataa ggaccaacgc
    13981 ctaagcctag gtctaaacca ataaagtagg tagataaagc aatactgatt cgatgttcgc
    14041 ggacgatttt taaacaaaca gcctgtccat ttgacataaa cgtaccataa cctaggccga
    14101 ctaatgctcc agagataagc aatgtcacac tattcgtcgt tacactcagt aaaaataatc
    14161 ctgctgttaa gaataaatag ctaggataca tcacgtattg ttctcctttg acatcgaaaa
    14221 tccttccagt caatggacgt gtaaatgtga tgaccaaagc atatacgacg aagaaaaatg
    14281 acccagcagc aactaagtgg attacttttg tataagaaga taaaaatgat aaaacacttg
    14341 aataagaaag acccatcaaa aaggcaattc ctgtaatgaa aagtgctttc ttttcaataa
    14401 aactattgat attccatgag cgaagagata ttttttgttc ttcagataat ggaatatttt
    14461 ttacaggaaa gacaaggcag gcaatcgtaa caaagaagac cagtacaatt gaaaaccaga
    14521 taatgaaacg aaaatcagtc atattcagca aaatcattcc taaaaatggc ccaacagcgg
    14581 cagctaaact agtacttaat ccataataat tgatgccttc ccctttttta gatgcaggga
    14641 tatatgcagt aacgatagca tttgtagctg tagaaactgt accgtagccg aatccattca
    14701 agaatcgaac taaatacaat gccccgatag ttggcgtata aagatatgct aatgttgaaa
    14761 ggagatagaa gatcgcgccg cctcttaagg taaacttccg accaaatagt tctaactgtt
    14821 tccccatgaa taagcgtgcc agcaatgttc cgatgatata gatcccagaa gcaaaacctg
    14881 cttggctcaa gctggcgtgt aaggtgtctt gcgcaatgac tgccatgatg accatcaaca
    14941 gataataaat caggtagaca ataaaattga tcaatgtgat tccaataaaa tatttattaa
    15001 ataatttctt ttccatgtat gttatacatt ccccttaagc tgaatatgct tttaattttt
    15061 gtatttgaac ttctacatcg tgataattgg atggatagcg atcaacaagt tggcgaataa
    15121 ataaatctct tgtagacata aacagattta aaaattcttc gcattcgttt gttggattct
    15181 catccactgc tttgatcaat tcgatcgagt tttgatacgc atcatttaaa aagactaaag
    15241 aagctttcat atcaaatctt gtttgatatg ctgtttctaa tcgattaatg attgtgttca
    15301 tccagtaatt catgtttttt ccctctattc ttaaaaaatt ttacttctgc agtataacga
    15361 ataaaaaaaa ggaaaaaaat cgcataagtg atggaaaaag gtacttaaca aatgttaata
    15421 tcattagtaa aatacctttg gactttaaaa agttttaaag tactgtatga tctttttaga
    15481 tgaaagtttg gatgggggag catcattgga tagtagagtc ttaaaggaat atttggacaa
    15541 aaatgatttt ccgattatac gcaaaggata tcataaatat ttgacattcg aagggatgga
    15601 agattcccat acgtatatct tgaaagaggg aacggtaaaa gcaagtgtta tttcaaatga
    15661 tgggagagaa tttaaccttc gctatatcaa agatcttgaa atcgtctctc ttttaaaaga
    15721 cgaatattca caattcatcg attcgccgta taatattcga gttgaatcag aatatgcaga
    15781 gttttatcga atcaatcgtg tgcgcttttg gcaaaatatc aaccaagacc caaagctaca
    15841 acactatgta aaagagtatt accgctatcg tctgctttat tcgatgaaaa aaatgcagca
    15901 aatgctatta aacggaaagc tgggagctgt ttgtacgcaa ctttacgaat tatatgattt
    15961 attcggtgtg cggacagaag aagggatgct gatcgatttt tcgatcacga atgaagaaat
    16021 cgccaaattt tgtggcatct caactgctag cagtgtaaac agaattttaa aacaactgaa
    16081 aaaagatggt attatcaccg ttaaagacca tcatatcgtt attttgaata tggacttgtt
    16141 agaagacaat attatctttt gatgaacaaa gaggttgtga aatcagcgtt ttgacctgag
    16201 tattagagaa acaaacggaa aaatagttcc tcatattttg ccgttttttg agctaatacc
    16261 gagggtcagc tgattgaaca ccgtttacca agaggttgtg agcctgccgt ttaactctga
    16321 gtcacaagga acaatttcaa aaaacagctt ttcatgtttg atgaatattg tgacttgtga
    16381 ccgaggagtt ggtaggagaa caccgtttac caagaggttg tgaaaaagct gttctgcatc
    16441 aagtaataag aagagccaag taaaaacagt ctcttatgtt tttaacttgg ctggacttat
    16501 caccgtagat gtaagctttt gaacgccgtt tatttgcaac aaaaggggct gtgacacgat
    16561 ttttgtcaca gccctttttt tgcgaacatt catttagcaa tttttagaaa cttctgccgc
    16621 caccgccaaa agtcccgcca ccgctagaat gggtagtact tccgccaccg ccgcttccag
    16681 gaggtgggct tttggggatt cttcttgtcg tgacaaaaga atttgtcaga cgatcggttt
    16741 tttcagttaa tttgatactg gatttttctc ggaatggata tttgtagatg cctgatttca
    16801 attgataacg cgaaacagtc acaaaataaa agacaagact aaggataaga gccaaaacaa
    16861 cagcaatgat gatttctact gtcgtcaaaa ccttatagcg tgtaattttg ccagtttctt
    16921 cgtctacacg ataatgtcct cctggaactc cgtcttccac atatgttgct gatttagaca
    16981 ggtaagcttt tgcagcattg taataggcag catttgtcat ctgatcataa acatcatcta
    17041 agatcgaatc gattctgcta tcagtcaaat aatcgatcat attaccagaa gtcgaaatgt
    17101 agatttcacg ctgtcccata tctaatagca atactgagcc attttgatca tttccgactg
    17161 cgtctcttaa gtaattatca gcaaagtctc ttggttcttc tgaattagat gtagtcgtta
    17221 cgatcaagac tcgtcctttg attttttcat tcagcttttc tgcctgttgt tccaaagatt
    17281 ggatttgatc tgttgtgaat aacccagcct catcatttac cgtagctgta tctgcatgag
    17341 tagccaccgg ccagccaaca cttactagca aaagaaagaa taaaaaaaat tttttcatca
    17401 tatcaagtaa cctccgatca gaaagaggat cgctagccca gcgaaaatcc caagagcggt
    17461 cagtcccaat tttttctggc tgatcggcag gacaccgctg acctttcctg tttgtccatt
    17521 cattgcgtag tagtagactt ttttacttga gtcattgctt cgataagtaa caagccatac
    17581 cggcagtaat acgtaattat ttacttcgtt tgtgattgaa gcagaagttc gcacaccggt
    17641 caatgttgta tatccatttg cggtatcttt taacagcttc tctgaatagt cttttaattc
    17701 agattgaatc tgtgatttga ttgcctcata ttcgatatct cttttttctg cttggaaccc
    17761 ggctaaatac tggcttttaa aatcaattgc tttatctaac gggaaaggtt gcacgccttc
    17821 gaccatcttt tgttgcgtat tttttgataa ggcatttttt actagttctt taaaagaaag
    17881 cttgcctgct cttgaaacag caaattgctt cgtttctgtg tattcgatgt cacctatccg
    17941 ccatatgcgg ataactgtac cattcgcctg catggcacca tctacttcag catctgtagc
    18001 ccaataaggg aaatacacac ctgtcaactt atcgatttga tccttattga aaaaagcttt
    18061 gggaacaaac cattttttct tggtccaagc gagaaatctg ttgattgctt cttctttctc
    18121 gacagcaaaa ggaagtactt tatttggcaa gaattctccg cttaaacgtc ccgatagtac
    18181 gacgggatta tggcagtagt aacaataagt cgcagcagtt gtcgcatcag tcacgatctc
    18241 tgcaccacag ttgggacaaa gaaaaagatc tatcgctgcg gtattatctg cagattcgtc
    18301 cgctgtatct gaaaaaccgc ctgcctcgtc aaccgctttg cgctcggctt cattcatatc
    18361 ggcaagctgt tcttgggctg taaaagtaaa atcttcggta ggtgaaggtt cttctttgct
    18421 ttcttcgcca gccatacgcg cttctttttg cttttgctca tattggctga cttcttcttc
    18481 tgtatagata ttcaggcagt attcgcaatg aaatttttgg tctttgggat caaaagtcaa
    18541 cggaccgccg caattaggac atttatgtgt aagaacatcc atcagctgca cacctttcta
    18601 aataaattaa ttaacgggga ttcctttaaa cggtttacca cagtttggac agaatttagg
    18661 gatgccgttg gaaagatcca cgatctcatt gcattcactg catcgcattt gtagcttagg
    18721 ctgaacgttt tctacaggtt tggcagctcc gcagttggaa cagaattttc cggaattttc
    18781 tgtcccgcaa actggacatg tccaagtatc cgcatttcct tgtgcagttt gttgattttg
    18841 tttttctgct tgttgtttga tttgttcttg gttattttga gctgcttgag aaagataaga
    18901 accatttgca ttcattccca tacctacacc cataaagccg gtcattgctc ctgcttcatt
    18961 ttttccggct gcttccatac cacgtgcaat ggaaccttgc acgtagcctt cacgtacgct
    19021 aggatcacct agcatcgccc cttcgttacg catattgatc agtttcacag aatcatcggt
    19081 gtaagaaatg ctggctacag ccacagaaac aatctccatc ccacgtaatt cacgccaaga
    19141 atcatccaat gcagtatcca tgtatttgct taattccaaa ctcttagatg gtacataaga
    19201 aatccgttga ccatctgcag acatctgatt gattgctgat tgtagcgctg ttaggaattc
    19261 agctaaatac tgctcattga tatcattgat ttccacttgt gttttgtttt tagggattgc
    19321 gtttgtataa aataaaatcg ggtcaacgac atgaatagaa taagtgccat gtgcccgtaa
    19381 gaataattct gcgttataga aattgtcaaa gtagttcaac ggcgcgcttg taccgaattt
    19441 gattcccttt atttcttgga gattgatata aaaaacttgt tgtttctgcg gtgtgacgcc
    19501 gccaaatttg aatcggtcaa aagtttcagc aattgcttct ttcagtgttc cattgaacat
    19561 ggaaggagct gcgtcatttt taatggtgta ataaccttcc tcagcggtat aatcgatgat
    19621 ttttccacca tcgaccaaaa gcatcatcat gtttggatag acatggacga ctgttccgtc
    19681 tgttaaaaca tcttctgttc ctttacgatt ggagccacgt ttgtcatctt tgcggacttt
    19741 gacacctttt gtcatgaccg ttgtatcact catattgtct ggttcgatga cttctagcca
    19801 ttgatctgcc agaccgccgc caaccatact tgttgctgct ttgataagac ccataaaaaa
    19861 ttcctcctct gattcagcta gtgccaaaca attattgttt atttattata ccataggaag
    19921 atgtgaaact tctcggacta gagacggaat tgaaatggaa aattgcgtat tgtttaaata
    19981 cctgaaaaag ccgagaagga tagtagtttt tttacctaat atcacgtata ataagagata
    20041 gtgaattttt taaaaaaggg ggatccttat ggcatatcaa gcactttatc gagtctggcg
    20101 ttcgcagcgt ttcgaagaca tcgttggaca aaaagctgtg acacagacac taaaaaatgc
    20161 tattgtttcc cacaaaacct cacatgccta cttgtttaca ggacccagag gaaccggaaa
    20221 gacgagtgca gcaaagattt tcgcaaaagc aatcaactgt ccgaacagta aagacggtga
    20281 gccatgcaac gaatgcgaaa tgtgtcgatc aattactgct ggtacgcaag aagatgtgat
    20341 cgaaatcgat gctgccagca ataacggagt cgaagaaatc cgatttatcc gtgatcgggc
    20401 aaattatgcg cctacaaagg cagcgtacaa agtgtacatt attgatgagg tacatatgct
    20461 ttcaacagga gctttcaatg ccttgttgaa aacattggaa gagccaaaag aaagtgtcat
    20521 attcatctta gcaacgaccg aacctcacaa aataccagct acgatcattt cacggactca
    20581 gcgatttgat tttaaacgga tcaatacggc agatattgtc gaacatcttg aatttatctt
    20641 gaaagaatcg actatcagct atgaaccagc tgcattgaat gtgattgccc gttctgcaga
    20701 aggcgggatg cgggatgcat tgagtattct tgatcaggca atctcgttta gtgaaggaac
    20761 aattacttta gatgatgcca tgcaagtgac aggtagctta actgacgaaa tgatggacag
    20821 ttacttgagt gcttgcgtga aaaaagaagt accagaagca ttggaaacat tgaaccaaat
    20881 tctcgcagcc ggcaaagaat cacgtcgctt tctagaggat atgttacaat actgccgtga
    20941 cttgctgatg tatcagcaag cacctaacct agttgaggaa caatcgagta cgatcagaag
    21001 tacatttaca gaattggcac aaactgtttc agcggatcag ctgttttcaa tgataaagat
    21061 tttgagcgat actcaaaatg aaattcgttt taccaatagt gccgctattt atttggaagt
    21121 cgctacagtc aaacttgcac agctaccgtc tgcttctgtt ccttcagcag atgtagcatt
    21181 tgcagatgat cagatagtaa aacagctaca acaagagatt aaggaactaa gaaacgaaat
    21241 caaggaacta cgcagtaata caggaattga gaatacaaaa gtacagccgg tacagcaaac
    21301 aaatcataaa aaacagacaa gtacctatcg tgtaccgacg gaacgagtat ataaagttct
    21361 gcgggaagcg acaagacagc atctgaacca agtaaaagaa gtatgggaag acttgctgat
    21421 gagtctatct gtcactcagc gagcaatgct taaagcaagc gaaccagttg cagctggacc
    21481 tacaggacta gtgattgcgt ttgattatga gattgtttgt caaagagcag caaatgacga
    21541 agaattgcag ctttcggtac acaacaactt aagccgaatg atcaaagatt atgcgcctga
    21601 tcctgtttat attacaagag aaagctggcc agaacttcga agaaattatt tgacgcaggc
    21661 acaagaagag ggaacagaaa actcttttgc ttctgaagac tcagaaggag aaatcgagtt
    21721 gcttcctcaa gaacaagaag taccagaaga aacacttgta gtaaaagcag aggaactgtt
    21781 tggctccgaa gctgttacag tggtagatga ttaataaaaa ggagtagata attatgatgc
    21841 gtggaatggg caatatgcaa ggcatgatga aacaagtaca aaaaatgcaa aaagaaatgg
    21901 cagaagcaca agagctgcta aataaaacag agtttacagg taaagccacc aatgaattgg
    21961 tcaaagcggt ttttacaggc gatcgtcgca tgaaagatat ccaaatcaat gaagaagtcg
    22021 ttgatcctga tgatatcgag atgcttcagg atcttgtcgt aatggcagtc aatgatgcga
    22081 tcgcacaaat tgatgtggaa actgagaaaa aattagggaa atacgcaaaa ggtttgccag
    22141 gattttagtt ttaaactgaa ggagtaatga atatgcaata tccagaacca attgcgaaac
    22201 tgatcgacag ctacatgaaa cttccaggaa tcggtcagaa aacagcgaca agactcgcct
    22261 tttatacgat cgatatgaaa gatgaagtag taaatgaatt tgctaaatct ttgttaagtg
    22321 taaaacgcga tttgcatttt tgtagtatct gcggaaacat cacagaagaa gatccctgcg
    22381 aaatatgtag aaatccttca cgtgatcgaa gcgttatcct agtggtcgaa gagccgaaag
    22441 atgtaatggc aatggaaaaa atgcgagaat atcacggact ttatcatgtt ctccatggtg
    22501 tgttatcacc gatggaaggg acaggtccag aagacatcaa tatttcttct ctgttgcagc
    22561 ggctgcatga tgcagatgta aaagaagtga ttatcgcaac aaatgcaaca acagagggag
    22621 aagcaacagc tatgtatctc tcacgtctga tcaaacccgc aggtatcaaa gtgactcgtc
    22681 tagcacatgg tctgtctgta ggctctgata tcgagtatgc agatgaagtt actttattga
    22741 aagctgtcga aggaagacgt gagttataaa tttctaatta agtgtttttt cagatacaat
    22801 ataaaagcag cacaagagat gggggcaaca atgtgaacgg actatttatt acaatcgagg
    22861 ggcctgatgg tgcaggaaaa accagcatct tgaatgaact ttaccctctt ttgaaagaag
    22921 tagcaaaaac agaaatcatt caaacaagag aaccaggagg cattccgatt gctgaagaga
    22981 tccgagcagt gatccttgat ccaaaaaatg atcggatgga tgaacgtacg gaagcactgc
    23041 tttatgcagc agcaagaaga caacatctag tcgaaaaggt tctgcctgct ctggcaaaag
    23101 ggaaaatcgt tttatgcgat agatttgtcg acagttctct tgcttatcaa ggtgcaggcc
    23161 gacgcatcgg cgttaccgag attgctcggt tgaatgagtt tgctacagaa ggtactacgc
    23221 cggattttac cctttatctt gacgtagatt cagacaccgg attaagaaga atcaagaaaa
    23281 acagacaaaa tcaaatcgac cgtttagatt cggaaggttt ggaattccac cagcgtgtac
    23341 gtcatgctta cttaaagctg gcagaagaga atccggaaag aatccacaaa gttgatgcaa
    23401 gaaaaagctt tgaagaagtg ctgcaaacaa gttatcatac aattattgaa cagtatccgc
    23461 aattttttga aaactaggaa ggtgaacgtt tatgaaaatt attttagcga ttatccaaga
    23521 caaagacagc aaccgtttat caaatgaatt gattgatgca aatatccgtg ccacaaaact
    23581 atcatcgaca ggcggcttcc ttaaggctgg aaacagtacg tttatcgtgg gtattgaaga
    23641 tgaccgtgta gaagaagcat tggaaatcat caaaaaaacg tgtgaatcaa gaaagcaatt
    23701 tgtatctaca cctgttacac tggatatttc gatggatggg ggcgtccctt atccagtaga
    23761 agtagaagta ggcggtgcca cagtcttcgt cttacctgtt gaaggattcc atcaatttta
    23821 ggaggagctg agctatgaat caagaaataa acttggctca aatgcaaccg atcgtgtatc
    23881 agcagcttca acggagtttt gagcatgggc gtatcgctca tgcttatctt tttgaagggg
    23941 agaaaggaac aggaaaacat gaagtaggta tatggcttgc acagcacctg ttctgtaccc
    24001 aaatgaaaga caatctgcct tgtggaaaat gcaacaattg tcagcggatc gaaaagaaag
    24061 aacatccaga tgttttggtt attgaaccgg aaggacaaac catcaaagtc gatcagatca
    24121 gacgtttgca gacggaattc agtcgcagcg gttacgaatc aagaaaaaaa gtttttttga
    24181 tcaaagaagc tgaaaaaatg aatagcagtg cggcaaacag tttgttgaaa ttcttggaag
    24241 agccccctgg agatttttta gcggtgttag aaacagatgc agtaggaaga attctcccta
    24301 ctattcaatc tcgttgtcaa gttctgcatt ttcaagaact ttcgaaagaa gcactgatcc
    24361 atcgattgca agaagagcag attccattgg aaaaagcaaa acttttggct ttcttaacaa
    24421 acagtttagg aaaagcagtt gaaatctctc aagatgaatg gtttaatgat gctaaggact
    24481 tgatttatca atggttcgtt tacttgcaaa agcaagatac tcaagccttt atctatgtcc
    24541 aaaaaaaatt ggtaaaatca tttaaagaaa aaacacaaca gtttacagga ttatctgtct
    24601 tgatgtttta ttatcaggaa gcacagcgtc aagcagtagc aaacggcgaa tatggcaaag
    24661 tgaaacagat aaaccagata attgaacgga tattgatcgc agagcagaaa ctacgcagca
    24721 atgtcagttt tcaggctgtt gcggaacagt tcgttttgca tacgattttt tagcttgccg
    24781 caaaggatga tgatcaagga ggatggaaat ggtagaagta gtaggtgtcc gatatagaga
    24841 tgcaggtcat atctattatt ttgcaccagg agactctgaa tatgtttata gtgacaaggt
    24901 attagtcgaa tctcagcaat ccttacatat tgctactgtt gtccttccta aaaaagagat
    24961 tgatcccaat gaccttcctg aagctatccg tccgatcttg cataaagcgt cacaagctga
    25021 attagaaaaa gacaaaaaaa acaaaaaaga tgcttatgat gcattgaaaa tcgcaaaaga
    25081 aaaagtgcag ttgcgtgagt tggaaatgaa aatggtcaaa gccgaataca catttgatcg
    25141 aaataaattg attttttctt tcacagcgga cgggcgaatt gactttagag aattggtaaa
    25201 agatctggcc gctgtatttc gtactcgtat tgagcttcga caaattggtg tccgcgatga
    25261 agcaaagata ataggcggaa ttggtccatg tgggcgtcca ttatgctgtt cttctttttt
    25321 aggcgatttc gtgcctgtat caatcaaaat ggcaaaagat caaagtttat ctttgaatcc
    25381 aacaaaaatt tccggtttat gcggacgctt gatgtgctgt ctgcaatatg agagcgaaga
    25441 atacgagaca gcgaaaaaag aactccctga ctttggaaaa gtaattgcta cacctgatgg
    25501 taaagggaaa gtcgtagggt tgaatctgct tagccgtatc gttagtattc ggctgactgg
    25561 acgggaaaat cctgtcgaat atgaatggga tgaattgaaa gaatttatcc aagtaggtga
    25621 gatgaatgga taagagatca ttatacgacg gattgaatca attagaatca gagttgagaa
    25681 atacattaac agaacttgtt gaaatgaagc atgctttgca tgagatcgta gaaaaaaata
    25741 caactttgga gatggaaaat caacgtctgc gggaacacct gcgggaattg aaccaagttg
    25801 cacaagctcc agctgaaaat gtgaagcagg aactttctaa gtctcgtatg aatcttgaaa
    25861 aaatttatga agaaggattc catgtctgct acgatttata tggatcaaga agggacaatg
    25921 acgagccttg tgcgttttgt ctagaagtga tctatcgcga aagcggtcga tgaccaataa
    25981 caagaggaga ctggagcgga gaaatactgc tccagtcttt ttattaagga gattgtgaca
    26041 gatgtataat caaaaaagtt tcaagggaaa tccggtatat ggggatttat atcttgtacc
    26101 gacgccaatt ggaaatttag aagatatgag ctacagaagt gttcgtatgc tgcaagaatc
    26161 cgatcttatc gcaagtgagg atacgcgtaa tacacaaaag ttattgaatc attttgaaat
    26221 ccatacaccc caaaaaagtt tacatgaaca taattataaa gaacgtgtcc ctcaattgat
    26281 tgctttgtta aaagaaggaa aaacgattgc tcaagtcagt gacgcaggaa tgccttccat
    26341 cagcgatcct ggacatgagc tagttttagc ctgcataaaa gaagggattt ctgtgatctc
    26401 tatcccagga cctacagctg ggatgacggc tttgattgct tcagggctag tgcctcaacc
    26461 atttttattt tatggcttcc ttccacgtaa gaaaaaagaa cagaaagaaa cattgaaaaa
    26521 gctaaaagaa cagacagtta cgctgatttt ttatgagtca ccttatcgga tcactgctac
    26581 attgacgaat ttcttagaaa tttttggaaa tcgccaagtc gttttgtgtc gggaattgac
    26641 aaaggtccat gaagaatacc ttagaggaag tacggaagag ctactcgctt atatcgaaga
    26701 acatccagta aagggtgaat gttgtctgct tgtagaaggg aatttgttcg aaatgccagt
    26761 gacggaagtt gatgaagagt tgggaacgtt aaaggaacaa gtagaagcaa agatcgcttc
    26821 aggcgaaaaa ccaaatgctg ctatcaaagc agtagcgctg aaaaatgggc tgaaaaaaca
    26881 agaagtctac cgtcagtacc atgaattaga ctgagatagt ataagttgtc tataatgaaa
    26941 gactaatgag gaaatcagct actaactttt caaatctctt gaacgcgaac gaatgttctt
    27001 gtataatgaa taagaggtga ggatgatgga gctgcaattt cctttacata atgatacatc
    27061 aagaaaaatc attcatattg atatggatgc ttttttcgct tcggttgaag aacgagatca
    27121 tcctgagttt cgcggacatc cattagtaat tgccagacac cccagtgaca ctggtgggcg
    27181 tggagtagtg actacagcaa attatgaagc aagaaaattc ggaattcatt cagcaatgag
    27241 tgcacaaaaa gcgtatgagc tttgtccgca agccatcttt aagcctggcg accatcataa
    27301 atacagcgat atttccaaac aagtacggga agtattctat cgttatacag atattgtgga
    27361 accagttagt atcgatgaag cgtatcttga tgtgaccgaa aataaaatca attgcaagtc
    27421 agccatcaaa atcgcccgaa tgatccaagc agatatttgg gagagtgtcc agctaacatg
    27481 ttctgcggga gtaagttaca ataagttttt ggccaaatta gcatcagact atcaaaaacc
    27541 tagaggaatc acggtagttg cccctcaaga cgctgtgcca tttttaaaag ctttgccaat
    27601 tgaaaaattt catggggtag ggaagaaaac tgtacctaga atgcatgagc tagggattta
    27661 tacaggaaaa gacctatatg aatgcacaga aatgatgttg attcgaaatt ttggaaaaat
    27721 gggctattct ctttatcgta aagtcagagg aatccatgat tctccagtaa acgttacaag
    27781 agagcgaaaa tctgtgggaa aagagcatac ttatgggcag ccgttgcaaa cggaagaagc
    27841 agtgctgact cagttgcgcc aactagctga aaaagtagaa gaagcactga gaagagtcca
    27901 aaaacatggg aaaacagtag ttttgaaggt caggtacacg gactattcta ctgtgaccaa
    27961 aagagtgaca ttgccagaat atatctataa aaaagaagca ctcttttatc aagcaagcct
    28021 tatatgggag gaaatcttgg gagtagaaaa aggaatccga ttgttaggga ttactttgac
    28081 gaatctggac ccgatgactt atgaaaacat cgtccttcca ttatgggaaa atcaagaaat
    28141 ataaaaacag ctttgagagt tgaaaccgga aatccgtttt ctctcccaaa gctgttttta
    28201 tatcaagtct tgctttttga tttgttcata ggtttctgtt gcatccgtac atttttccca
    28261 aatcacaact tgattggatt ctaaagattt ttggacgtca atgatccgct ggttgctact
    28321 tccgcgaaat tgtagtttta ggtcacgttt gcttaattca aagcgtccgt caacaaggat
    28381 atcgatttgc gaaaggagtt ctaatttatc ttctgaatct tgtagcaatt catcaaaggt
    28441 atagcctgtc catgaccaga tatcttttgt cgtaccgaac tcttttcgga tacgtcgtac
    28501 gacttgcaga caaacatctg tattcaaaaa aggttcgcca ccaagtaaag ttaatccttg
    28561 cacgtaatcg ttgcgcaagt cagcgatgat ttgttcttct aattcaggtg tgaatggttt
    28621 gccatatcga aaattttgtg cagctttgtt gaagcagcct tcgcaggcaa ataagcagcc
    28681 actaacgtaa agactgttgc ggacaccttc accatcgaca aaattaaacg gtttgtagtc
    28741 agcaatatag ttttggctgt agtcttttgc taaccattct tttggttttg gatttctcat
    28801 aaaaaaactt ctttcattta aggttcaaag atatagctat tgaagataaa atctactcga
    28861 ccacataaat aagaacaaac tgacctaaat ccattgttca agaaagcttg ttcttatttt
    28921 gatagagggc gttcaaagat acaaagccat cgaaagaggg tggtgaaaaa agacttgtca
    28981 tagcctctta ttctgaataa acggtgttca aaagcttgca tctgcagtaa taagcccaac
    29041 taaacgaaaa atatgaggaa ctatttttgt ttagctattc ttattacttg atgcaggaca
    29101 gctttttcac aacctcattt catgtgtttc acacgtgagg aaatttcttt atggcggcca
    29161 tgtaccatcg gacgagcttg cggatttcct aaatagccac aagtacgttt gactacatca
    29221 catgtttttg gatcatgatt tccacattct ggacattcga accctcgttc tgtcggtttg
    29281 aaatcacctt cgaaaccaca ttgatagcaa tgatcgattg gcgtattcgt accaagatac
    29341 ccgattttgt catatgcaaa atcccataca gcttctaaag ctttcggatt ttgttggagc
    29401 atagggtatt cacagtagtg gatgaatcca cctgaacaat attttggata atccttctca
    29461 aattccaatt tttcaaatgg cgttgggttt ttacgcacat catagtggaa actgtttgta
    29521 taatattctt tatctgtgat attttcgatg atgccgaatt tttctgtatc caaacggcag
    29581 aaacggtcag ttagactttc acttggagtt gaatagacac tgaaatgata accatattca
    29641 tccccccatg catctgcatt agcttttaat tctttgacga tatcaagtgt gaaagctttt
    29701 gcttctgggt ttgtttccca ttcgccaccg aagaaagctg aagcaacttc atacaatcca
    29761 atgtagccta acgatacagt agctcgacgg tttttgaata attcattgac agaatcggta
    29821 cgtgaaagac gtttcccgaa agcaccatac atatataaaa ttggcgcatt tgctggaatg
    29881 gcttctttac aacgttctac acgatagaga agcgcatctt tcatgatttc taagcggtca
    29941 gacagtaact gccagaattt attctgatct ccttttgatt cgatcgcgat tcttggcaaa
    30001 ttcaatgtaa caacacctaa attcattcgt ccgacattta cttcttgacc attttcgtct
    30061 ttccaccctt gcaagaatga acgacagccc ataggtactt tgaaacttcc agttaattca
    30121 acgattttat cgtaattcag aatatcagga tacattcttt tcgttgcaca ttccaatgct
    30181 agttgtttga tgtcgtaatt aggatcttca gggtttaagt tcacaccttt tttcaaagtg
    30241 aagatcagtt tagggaagat agctgtccgc ttttcactcc ctaatccatt gattcgaatc
    30301 tgtaaaattg ctttttgaat ttctctttca aaccagtttt ctcctagtcc aaatcctaat
    30361 gaagtgaaag gagtttgtcc atttgaagta aataaggtat tgatttcata ttccaaactt
    30421 tgcatagcat cgaagatatc ttttttggtt tttgcttttg catattcttt ttggcgttct
    30481 ggcgaatcga tccattcttc cgcgtctttt agatgttttt tatagttcaa ttctgcaaaa
    30541 ggagcaagca attcatctgt tcggtcggca gaacagccac catattgact tgacgctaca
    30601 ttggcaataa tctgtgagat ttgtgctgtg gcggtctgga tagattttgg cgattcgact
    30661 tcggcattgc cgattttgaa cccattgttc agcatgcctt tgaaatcaat caagcagcaa
    30721 ttcgtcatcg gtgtataagg atgataatcc aaatcatggt aatggatatc gcctttttga
    30781 tgcgcatttg ctatatgtgg tggcaacatt ttcagtccga ttgattttcc aacgatcccg
    30841 gctgtcagat ctcgctgtgt attgaaaaca ttactgtctt tatttgcgtt ttcgttcacg
    30901 acagtttggt ccttgttgat tagcttttca atcgaaaagt tgatatctgt tgctttactg
    30961 cgagcaaaat ctcgtttggt acgataattg atgtactctt ctgctaattc atattcgttt
    31021 ttttctagta atatatgttc cacgatgttt tgaatctcat agattttgac attttcagca
    31081 aaccggcttt tgatttcttg gacaaccaag tctgcaatca tttgaatttt ttcataagta
    31141 agtggtgata atgagccgtg aattttcttt tctgctttga tcagtgcttc attgatcttt
    31201 tgttcatcga aatcaacatg gcggccatcg cgtttgatga ctttcatctg ggatgtctct
    31261 ggctgctgag taacgacagt tttttcttca taatttactt tcattatctt caactcctgc
    31321 taaattgttc ttgtctatca taaaacaaaa tcggggaagg agcaactaaa tatcggctat
    31381 atatagtatt caatgtgctg tataattgga tttctatact atatgtagtg tatattttat
    31441 tgtgaaaaaa ggtgaaaact tgtagctggt ggatttgttt tttgcatatt taattttgct
    31501 gaataaaata attgaataaa attttttatt cagtccaagt aaaagtgaca aaaacataag
    31561 agcaaattat tcgtagatat gctactatgc aaataaatag aaatgaaaaa tgaaagagga
    31621 ggagaagaat tggaaaagat gatcgaagtg aaacatctaa gtaaaagcta cggcagcaaa
    31681 ctttctcccg tcaaagcctt agataatatc tcattcacag tagaagaagg cgagtttgtt
    31741 gggattatgg gcccaagtgg tgcaggaaag acaacgctga tgaatatctt gtccacgatc
    31801 aatttgccta cgatgggcag tgtctcgatc caaggaaaag aaatcacaaa aatgaaaaac
    31861 agtgagctca gtgactttcg tcgaaaaaaa ctaggattca tttttcaaga gttcaatttg
    31921 atcgataccc taaatgcaaa agacaatatc ctattgcccc tagcagttga acggatgact
    31981 aaagaggaaa tggaaaagag agtaagacat gtagctcaat tgttgaatat agaagaactg
    32041 ctcaaacggt atcccgatga actttctgtc ggacagagac aacgaattgc agctgctaga
    32101 gcacttgttg ttcagccaca agtgattttt gcagatgaac caactggctc tttggactcg
    32161 aagtcggcta cagaattgtt gaactacttg aagaccatga atcaaaaaga aaaagcaacg
    32221 atactgttag tcacccatga tccatataca gcaagctact gcgatagaat tttatttatt
    32281 aaagatggtg tgattttttc tgaagttgtc agaagaggga caagaagaga gttctttgag
    32341 aaagtaatag acatgcaggc gacgattggc ggaggaggaa aaatgaatgc tgtataaact
    32401 agccgttaaa agtttttttc ggcagtcacg aggctatctt gtttattttt tcagtttgac
    32461 tttatccgta atgatctatt attccttcag cgcaatgacc tacgatcaat ctttagtcag
    32521 aagagcaagt caagatactt cgatagatgg tggattgagt tttggtggat ttatcattac
    32581 tgttgttttg ctttttttcg tattcagtgc caaccgattt ttcttgaata gaaggcaaaa
    32641 ggaaataggc atctatcagc tttttggtat gaataaactg cagatatcag gtatatatgt
    32701 gttagaaatc atgataattg gattgttcgc ctgtatttct gggatattac tcggtattat
    32761 tttttccaaa ctcttttcaa tgattttggt tcgaatgatg gatatggatc ttactagtcc
    32821 attttttatc tccattccat cagtagtaga tactttattt gcttttttca tcatcctttt
    32881 agcagtatct gtatattcaa tatggaaaat atggcgctat ccaatgattc gaagttttgg
    32941 agaaaaagaa caagcagata gttcaacaat gcgcttcagg acaaggcacc gattactcgc
    33001 agtcatcggg ttactacttt taacgagcgg atattttgga gctagtcatt ttagggaaat
    33061 cacttcatgg atgatcagtt atcattatct tgatacatta gttttctttt ttcctttttt
    33121 aatttttttc gtttgtgtgg tcggtactta tttgtttttc tgttatacat ttcggttatt
    33181 tttgatcata ttgagtaaat ggaagattta ttactatggt atcaattttt tgataatggg
    33241 taacacgcaa gttcatttgc tcaaaagttg gcgtacaaat tctctgatta cagtcattct
    33301 cggaatttct ttaatgacaa ttggcggcac ggctagtatc tctactattt tatcctacca
    33361 ggagaaagtt tcctccccga tggactatca gtttgatgtt gagacagaga aaaaaatcaa
    33421 gccgattcta gcagaggaag ggcagaagat aactaaagaa atcaccttgc attataaagt
    33481 cattgggagt atctatagtc aaaatctcga agaacctatg tttcaaactg ctaatctgat
    33541 cacggaaaca caatatcaag ccttcagaaa agttaatcca gatttgccga acatttcttt
    33601 gaaatcacct ggtcatactg ttttgcttga tcaaatgcaa actctttttc ggaatatttc
    33661 attatatgga tctagtattg gactgccaga taatcaagaa ttgaagattc aacaaatgct
    33721 tccaagtgta ttaggtgacg aaacaatggt atatctaagt cctgtactga ttgtagatga
    33781 taccgttttt gaaaaagcaa aaggtgtgga ttatcaagta gtcaatgtag atgtatcagg
    33841 tggaaataat gaaaaaatag atgaacgact gagcaatgac ctgtcgataa agtggctcaa
    33901 tgctgtttat tattcttatg atatcgtaaa tggaagtcta caaggagaaa ttagcacaaa
    33961 gaaacttccg gatgaccaaa tgaaggaagc acaatttagc caagaaagct ctcgtttgaa
    34021 tttctcttcc agctattcga aattgcgtgc agttaatcgg cgaatcggta tcaatatttt
    34081 tgtcacacta tttgtcggga tgatcgtgat tattgctact ggtagtattt tgacagtccg
    34141 gcaattagca gaagcagagg aagaaaaaga aaattatcac ctattgacta agctggggat
    34201 tccacaaaga aggatcagac ggatgatctt cgagcaaaac gcacttacct tctttccacc
    34261 catgatatta gggatcactc acgcagtatt tgcaatcaat gtcttcactc agtatataaa
    34321 aactgccgat tactggttgg cttatcttgt gagtggctta ttgatcctta tctatctttt
    34381 gctttatgtc attacgagtc agttatattg tcggattatc gaggaatgat atacggaata
    34441 agacaagata ataaatagaa ctaaattttg aataccattt atttggaata agaggttgtg
    34501 acacgatttt tgtcacaacc tctttatttt ttatattttt taaaagtacg agaaattata
    34561 aagaaaaaag cagtgatttg atgtgctatt tttataaaag ctatgtgaca aaactgttag
    34621 taaaaaaacg gtttctgtaa gctagacaca tgtttctttt tgtcaaaatt agttacactt
    34681 tgtgtgaggt tatatgagga gggaatccaa tgaacaaatg gcgttctaat ccaaaattga
    34741 attattgggg aaaattcatc attcgaacaa ttttttatag tgcagtactg ctgttcctga
    34801 tttatctgta tcactataaa aatattcaag gaggaacttt tatctataac gaattttagg
    34861 aggaagagta tggaaatcaa aacgattatt gaagcaatcg atgattgggg aataaatgaa
    34921 cctgatcgag ttgcttatca ggcggatgag acgcatactt ttggtgaatt gaaacaagca
    34981 tcagacgcac ttgcttatta tttagaaaaa aaggtagaag gcgatggacc aattgtcgtt
    35041 tttggcaatt tggagtttga aatgattgtc tcatttctag gggttgtcaa atctggccat
    35101 gcctatttgc cgattgaaga gcatacaccc aaggagcgta tcctatcgat ctttcgggtg
    35161 gctaaaccat ctatggtcat cagtatcggg gactggatag aagatattcc ttcggttcct
    35221 gtcataacaa aaaaagaatt tcaagaaatc aagaagatac cagtaggatt ttatcccaga
    35281 aatagcgtaa aaggtacaga aaatttttat attattttta cttctggtac tactggagaa
    35341 ccaaaaggcg tacaaatcag tcatgataat ctagtcagct ttgttcaatg gacgatggaa
    35401 gactttggga tcaagcctgg tatgcatttc ttagcccaag cgccattttc ttttgattta
    35461 tcggtatttt ctatttatcc tgcattagtt tctggcggaa tgctgaagcc gttaaataaa
    35521 gcagttgttc aagactttcg tcaattattc gcgacattgc cagccttgaa gttgaatgtg
    35581 tgggtttcta ctccatcatt tatggatatt tgcttgatgg aacctacatt caatggagaa
    35641 aatgtgccgg aattggacat gtttttattt tgcggagaag aattgacgaa aaaaactgca
    35701 gaaagtctac ttgatcgatt cccaaatgca cggatatata atacttacgg tccaacagaa
    35761 gcaactgtag ctatttcaag tattcagatt gaccagcatg tactagatag ttatgaccga
    35821 ctaccgattg gctacgtaaa aaaagacacg aaagtttcta ttgtccaaga aggtaaacct
    35881 gtttcaaaag gagaaacggg tgaaatcatt attgcaggac caagcgtatc aaaaggttac
    35941 ctgaacaatc ccgaaaagac agctgctgcg ttcttttgtc aaaatgactt agcaagttac
    36001 catacagggg atgcaggtag actagatgaa tatgggcttt tattttatga aggacgtatg
    36061 gatcagcagg tcaaattaca tggataccgg attgaactcg gggatatcga acattatctg
    36121 ctccaagaca accgaatcaa acaagctgtc gtcgtaccaa aataccaagg aacaaaagta
    36181 cagcagctgg ttgcttttgt cgtattagaa aacaaaacga aacagccgga ttttcagttg
    36241 actaaatcta tcaaagaaca attactagaa gttgtaatgg attatatgat tcctcagaag
    36301 ttccattatg tcgatctgct gcctcagaca gttaatggaa aaatcgatcg aaaaaaatta
    36361 acagctgagg tgaatcctga atgatgttac ctcatatgat cccttatgca gagccgtttt
    36421 atttttttct tttagccatt gcgcttgtac cgatcgttct atctttattg atatgggaaa
    36481 aaagattacc agtttatcaa tcagcagtga cacttttctt tttatttgtc agctttggag
    36541 gtaattattg gcaacaggga gcggcgctga ttgggtatgt tttgtggcag acgatacttg
    36601 tatggggcta ttttgtttat cggcaaagga aaaatcagac aggatggttt tttgccgccg
    36661 ttattttagc gataattcca ctgtttttaa cgaaagtgac tccttttttt gaacatggaa
    36721 aagcatcgtt acttggtttt ttaggaatct cttatttaac ctttaaatct gtacaaatga
    36781 tcatggaaat aagagatggc atgatcaaaa catataagcc atttcgttat atccagtttc
    36841 tgctgttctt tccaacaatc tcttctggac caatcgatcg ctataggaga tttgaaaaag
    36901 atcagctcca tccgcctgtt cgtgataaat atgttgatct tttgggaaaa ggcgtccaaa
    36961 atatttttgt cggtttttta tataaattca ttatcggtta ttattttggt caagtactgc
    37021 ttcctgtagt gggacgcatt gccttacagc atggtggtat ttcatgggca ttagtaggtt
    37081 atatgtacgt gtacagtatg tatttgtttt ttgattttgc tggctatagc ttatttgcag
    37141 tcggtacaag ctacatgatg ggatatcaga caccaatcaa tttcaataaa ccttttttat
    37201 catggaatat caaagaattc tggaatcgtt ggcatatgac gctgtccttt tggttccgtg
    37261 attatgtata tatgcgattg atgttcttca tgatgaagaa aaaatttttt aaaagcaaga
    37321 tcgtaatgtc aaatatcggt tattttgctt tgtttcttct aatgggtata tggcatggat
    37381 tgacgtggta ctacatcgta tatggactgt atcatgcttg tctgatctgt ctgacagatg
    37441 catggatccg atttaagaag aagcataaag agcagttgcc ttctaacaaa tttacgcatg
    37501 gcttagccgt atttttgaca tttcaagcag tatgttttag cttcctgatt ttttcaggat
    37561 ttttagataa actttttttt agctaacgaa tagtgacata ttaatttata taacaaagga
    37621 gaaaaggaaa atggaagaac aaattttatc aatcttagaa gaaataacag gaacagatga
    37681 agtaagaaaa aatcgtgata ttgatctatt tgatgaaggg ttgcttgatt ctttagcatc
    37741 tgttcaatta ttagtcgagc tagacggaga gctggatatc caagtccctg tatctgaatt
    37801 cgagcgagag gattggtgca caccgaataa aatcattcaa caagcaactg cattgaaggg
    37861 ttgagtatga aaaagaaact ttttgctatt ttcggcccgg ttgttttagc tgttggctta
    37921 ctgtttgtgt tttttacctc ctcctatcaa gtagatatct ctaatccaga aacgattaga
    37981 cgtgcctctt cttccatgtc agtgaacgtg ttgaaaggag atgcgataaa aaattatgca
    38041 ttatctgaaa aacaatatat tccttttttt ggctcaagtg aattaagcag aatcagtcca
    38101 tttcatccgt ctgttctggc agaaaaatac cagcgaaact atcgtccatt tttgctggga
    38161 gcacccggga cacaatcgtt aagccaatat atgatgatgc gttctgcagg agatgctatg
    38221 aaaaacaaga aagtcgtctt tattatttct cctcagtggt tcgttaaaaa tggtgtaaaa
    38281 actgattact ttaatacgta ttattctgaa cttcaaacat acgactggtt gttttcaatg
    38341 aagaaagtaa cgcctgctga tcgctattta gctagaagat tattaacttt ctcaaaagta
    38401 aaagagaatg atacgttgac ggcgattctg caaacgatca aaaaagggaa gctaccttta
    38461 cctgaatctt tgaatcagct gcgcagccaa tggaacatgc tgaagagaga ggatgaagta
    38521 ttcagcaata ttgggttgaa agatcgacag caaaaaatcg atcatgagtc aaaacgatta
    38581 ccaaaacaat accaagaaac agaattatcc attttagcaa atcaaattgg agaacgagaa
    38641 acgacgaata atccattcgg gttgaaaaac gatttttata cgcatcgtat ccgagcccac
    38701 gagccagagc tcaaacagtc acaaaaaaat tgggattatc gtttttcgcc agaattttct
    38761 gattttcagc tggtcttgga tcaattagca aaaaaccata acgaagtatt gttcatcatc
    38821 ccaccggtta acgagaaatg gagcgattat accggactat ctcaagaaat gttacaagga
    38881 tttgccaaaa agatcaaatt tcaattaaat agccaaggat tcaatcgaat agctgatttt
    38941 gtcaatcaag cgggtaccaa ctattttatg gaagacacga tccatctagg ctggaaaggc
    39001 tggttggctg cagatcaaca gatcagaccg tttttagaag aaaatcatat tactgctagt
    39061 aagtatcatc ttgacgatgc tttttttagc aaatcttggc aacatcaaat accagataaa
    39121 ctacaattaa aataaagaaa acaggcgagt gttgctcgct tgttttcttt atttttgaat
    39181 attctgaata aaagataaaa ataccaagtt tgcctgaaca aaaatcataa gcaatggtat
    39241 aatcacaata tgaatataga aatgggggaa aacatttgga tacaaaagaa gaacagctac
    39301 ttattgattt aacttctgca aaaggagtac ctggaaatga agaagaggta agagaagtat
    39361 tcagagaata tgccaaacca ttcgctgatg atatttttta tgacggttta ggcagtgtga
    39421 ttgccaaaca tggtgctggc ggaggcccca aggtctttat ttctggacat atggacgaag
    39481 ttggttttat ggtaacaaaa ataaccgaaa aaggattctt ggaattccaa actcttggag
    39541 gttggtgggg gcaagtcatg cttgctcagc aagttgaaat caaaacacgt gaagggaaaa
    39601 tcgtccacgg tgtgattggt tccaaaccac cacatgtttt aacacctcaa gtaagaaata
    39661 aaccttatga aataaaggat atgttcattg atattggcgc atcaagccaa gaagaagcca
    39721 aagagtgggg catacgtcct ggagatatgg tcactccata tattgaatac aaacgaatga
    39781 atggcagtaa atatttactg gcaaaagcat gggataatcg tatcgggaca gctgtttctc
    39841 tgcgagtatt agagaatcta tctaaagaag cacacccaaa tgttttattc gcaggaagcg
    39901 atgtgcaaga agaagtaggc ttgcgaggtg ctcgaacaag tacacacctt gtaaatcccg
    39961 atattgcttt tgctttagat actggtacag caggagacac tccaggaatg acaccaaaag
    40021 aagcagattc gattttagga aaaggcccac agattttgat ttttgatgca tctatgatcc
    40081 cgcataaaaa attattgaat tttgttattg atgtagcaga ggaaatggat attccattcc
    40141 aatatacagt gatttctggc ggaggaactg atgcaggaca aatgcatttg acaagagatg
    40201 gtgttccgtc tgtagccatt accgttcctg ttcgttatct gcattcccat acatcagtga
    40261 ttcatgaaga tgattatttg aatacagtga aactagtcac agaattagtg aaacggcttg
    40321 atagtgaaac agttgaaaaa attcggagtt atgaataatg aataatagaa tacctatttc
    40381 tgaatatcgg aaaaaagcac gagtttcttt ggaaaatcaa tggggaatca atacttggct
    40441 tgttttctta tctataatat ttacgagcgt catccagaac ttttttgacg gtttcagtcc
    40501 ttttccggaa gaaagcatgc agcagcactt attgagtttt ctagtcgata atttactttt
    40561 attcgcattc aactatgcat tgttttacat tgcgctagta gttgtacggg gtggcagacc
    40621 aaaaagtaac cttttatttt cagttttcca aagaaagtat tttggttcga tacttggcat
    40681 caatttgatc aattcagtca tcaactggct actcaacagt ttaatctttc tgcccatgtt
    40741 tttaatcagc ggagtgagta cttatatgca gctgcttttc agttcaaatg cggtacctac
    40801 gggtgtcatg ccagaagatt ttcttgatat cagctttgtt ttatcgatga tagggatgat
    40861 ttttgtttca gcactcatca tgagtattgt tggcggttta ttccaatttg ctgcatggac
    40921 aaagttcgac tatcctgatt tgtcggttat tcaatgtttg aaatatggct ggtttttatt
    40981 gaaagataga attggtacgt atattttgtt gcagctgtct tttatcggct ggtatttgct
    41041 aggagcaatc gctttgttca tcggtctttt gtgggtcatt gtttatgtga atgtgtcagt
    41101 tgcagaattt tatgaacaag cacggattga aaaaggaggt ccagacgcct attttactta
    41161 gcatgtaagc agtttattca tcaaaaaaat aacttttgtg gtaggataaa tctttgaggg
    41221 ggaatgtacg atgaaattaa ctgttttagg atgcttagga gcgtatcctt ataaaaatca
    41281 agggacaaca ggttatttgc ttcaatctga cgggttcaat ttgttgatcg atgcaggtag
    41341 tgctacgctg atcaaattac aagaacacct tgatccactt gatctagatg ctgtgatcct
    41401 tagccattat catcatgatc atattgctga ccttggtgta ttacagtatt actggcaact
    41461 tcatcctaag agaaatccgg agacattgct ttcaatttat ggacacacaa aagattccat
    41521 tcactttgaa gaattgacgt tggaaaatgt ctcaaaagga catccttatt ttgaagctga
    41581 agaattaaaa attggtcctt ttctgattac ttttatggaa acaatccatc cagtagtatg
    41641 ttacgccatg cgtatcgtag aagaaacaac ggggaaagta ttcgtattta caggtgattc
    41701 aggttatttg gaaagtttcg ctgattttgc gaaagatgct gatttgtttc tagcagatac
    41761 ctatcttttt gaaggaaatg aacatcatca tgcccatttc acttcaaaag aagctggaga
    41821 acttgcgaaa tcagctaacg taaagaaact tgtacttaca cacctacctc agtttggtga
    41881 tttagaacaa ttgaaaaatg aagcgcaaaa ggcagcaggc aaagggattg atatagaact
    41941 tgctgcagtt gacaaagtgt ttaacattta ggaggaagaa catgattttt gtaccaaatg
    42001 aaaaccacga cccaagaatc aatttagcaa ttgaacaata tttgctgcaa gaaatgcctt
    42061 tagatgaacc tattttgctc ttttatatca atgaaccttc aatcatcatc ggcagaaacc
    42121 aaaatacgct tgaagaaatc aatcgagatt atgtggaaga aaatggcatt catgttgtcc
    42181 gtcgcttaag tggaggcgga gctgtctacc atgattttgg aaacctgaac tttagtttta
    42241 tcatgcctga tgatggggat tcattccgtg actttgcgaa agtaacacag ccaatcatcc
    42301 aagcacttca tgaattgggt gttgctgggg cggaattgaa aggccgaaat gatctagtca
    42361 ttgatggcat gaaattttct ggcaacgcga tgtatgctac caacggtcgg atgtttgctc
    42421 atggaacaat tatgttcgac tctgatatca atgaagtagt caatgcatta aaagtaaaaa
    42481 aagacaaaat cgaatcaaaa ggaatcaaat cgatccgttc tcgtgtaacg aatatcaaac
    42541 catttcttcc agaagaaaag caaaaaatga caacagaaga atttcgtcaa gaaatcttgt
    42601 tgaaaatttt cggcgtagag tcagtagaag aagtaaaaac gtacgaattg actgatgaag
    42661 attggaaaaa aatcaatcga atctctgagg aatattatcg aaattgggat tggaattacg
    42721 ggaagtctcc agatttcaat ttctctcgcc aaaaacgttt ttctatcggt tcgattgaag
    42781 tccatttgaa tgtctcagaa ggaatgatca aagaagcaaa aatctttggc gatttcttcg
    42841 gactaggaga tatctctgac gtggaaaaaa aattggttgg acagaaatat gataaagcat
    42901 ctctatcaaa aatagtcagc caaattgatg tgaagaaata ttttggtgcg atagaaccag
    42961 aagaattgct taccttactt tattgaaaat aaaaaatagc ggaatccaca tatatggatt
    43021 ccgctatttt ttatacagga ttcgggtaat ttcgagagag ttgaacagtg atccgatcaa
    43081 tgaaagtatc tttttcctgc gttagtgttc ctgtgtaacg atccgctacg tctttcatca
    43141 tcattaagtc aaaacgttcc tgatcatcta attcttctgt gatgcctcga ctaaataggt
    43201 ttgtatcgta atgtgcacta tgttcgcaac aaatgacgaa atgttcctct tgttcgtgta
    43261 tcgacaaata aatttttcga tacagtggat tttcgatggc atgagtttct ctaaaggaat
    43321 gctctaaagc gtggatcaaa agttgagcca gatcgtcatc gttgatagga agttcttcgg
    43381 gaagatctgc ttggaaggtt atctgaatat tccgtttggc agctaacttc tggtaacgcg
    43441 ctaagataag atttgtcacc tggtggttgc aaaaagaaca cagcatttcg aaattttttg
    43501 cttcttctaa tatcttttcc acatagtttt tagcttttgt ttggtccgta tgcattaaat
    43561 cttgcagatt ctccatctct tggacaaatt ccaggcgaag tgtatttact tcttggatat
    43621 gctgtcgaag ctgctcataa tgttgctcca acaaatcatt tttgattttt aagaaatcta
    43681 cttgtctccg atctttgtcg gtatttaaga tgtgatcgat tagattgtag ctgataataa
    43741 cgattagaat gataatatat aaaatcgtag accaattgat cgttgtttga tagataccta
    43801 atgccgtttg gatgtaaatc aagcaatgga taatggctac caagacgatc caaggtgtac
    43861 aagctacata aaaacggtta ttcttatatg cttcgccaat gcatgcaagt gaagtgacta
    43921 aagtgcttat aacactagca atattagcaa tcggcattaa ttcaggaagt tctgcaggag
    43981 taaaagttgc ataaagcaga acgccgataa aaatcaaaag ttggaacgta caaaaaattc
    44041 cgtaccattt tttatagtaa aacattcggc tccaatagta gcagatgatg aaagctgacg
    44101 ttaagataat aaataaatga gataaaaaag aatgaacgaa tggttcaaaa agaataccac
    44161 ttaaaatatc ttctgataca gcttcaaatc ctaatgccaa agcaaagcaa cttaagagaa
    44221 taagtgagta ttcaagacgt ttttgtttat acatcaagta gatcgtatag aaaaaggtcc
    44281 ctatagcgat aaaaacagcg attatcatcg tcaatacttg cggcactgat tgtgaataaa
    44341 taaaactaat caatggtcca gttgttccta gataaacttt cggtggcagt ccagcatagt
    44401 tctgataagg agatgagact gtaagggtca atttttttcc gatataattt gctggtaaat
    44461 ctatcacagc caatgagagt ccgggattgc tttcttcctg ataatctttc cgttggtata
    44521 aaatcttttc gcctagatat acagtaatcc attgatggtt tcctttgatt agtaaatttg
    44581 cttcgtccaa cggtttttca agtgtcgttt ccataatgaa tgtttcgtct ttatccacgg
    44641 taggaatcgt acgagtgtac ttgctgtcaa acttaaaatc aggatcatct tttgtataga
    44701 aaacccacga atcttttatt tctttcattt gattgctgtc cgcaggagaa aaaataaaat
    44761 aaaagaaat
//
LOCUS       DADVXV010000014        41704 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.014, whole genome shotgun sequence.
ACCESSION   DADVXV010000014 DADVXV010000000
VERSION     DADVXV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.014"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(12..617)
                     /gene="dhaL"
                     /locus_tag="KB969_000720"
     CDS             complement(12..617)
                     /gene="dhaL"
                     /locus_tag="KB969_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBB6868732.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="KB969_000721"
     CDS             complement(645..1655)
                     /gene="dhaK"
                     /locus_tag="KB969_000721"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBB6868733.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="KB969_000722"
     CDS             complement(1630..2076)
                     /gene="dhaM"
                     /locus_tag="KB969_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBB6868734.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            2179..2499
                     /locus_tag="KB969_000723"
     CDS             2179..2499
                     /locus_tag="KB969_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBB6868735.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(2611..3480)
                     /locus_tag="KB969_000724"
     CDS             complement(2611..3480)
                     /locus_tag="KB969_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6868736.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(3576..4880)
                     /locus_tag="KB969_000725"
     CDS             complement(3576..4880)
                     /locus_tag="KB969_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6868737.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(4877..5386)
                     /locus_tag="KB969_000726"
     CDS             complement(4877..5386)
                     /locus_tag="KB969_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868738.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(5561..7696)
                     /locus_tag="KB969_000727"
     CDS             complement(5561..7696)
                     /locus_tag="KB969_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6868739.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(7779..9434)
                     /locus_tag="KB969_000728"
     CDS             complement(7779..9434)
                     /locus_tag="KB969_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6868740.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(9436..9750)
                     /locus_tag="KB969_000729"
     CDS             complement(9436..9750)
                     /locus_tag="KB969_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6868741.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            9920..10180
                     /locus_tag="KB969_000730"
     CDS             9920..10180
                     /locus_tag="KB969_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBB6868742.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            10194..10508
                     /locus_tag="KB969_000731"
     CDS             10194..10508
                     /locus_tag="KB969_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBB6868743.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(11238..11792)
                     /locus_tag="KB969_000732"
     CDS             complement(11238..11792)
                     /locus_tag="KB969_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBB6868744.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(11918..13847)
                     /locus_tag="KB969_000733"
                     /pseudo
     CDS             complement(11918..13847)
                     /locus_tag="KB969_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(14153..14869)
                     /locus_tag="KB969_000734"
     CDS             complement(14153..14869)
                     /locus_tag="KB969_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6868745.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="KB969_000735"
     CDS             complement(14870..16693)
                     /gene="glpO"
                     /locus_tag="KB969_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBB6868746.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="KB969_000736"
     CDS             complement(16707..18203)
                     /gene="glpK"
                     /locus_tag="KB969_000736"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBB6868747.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(18339..19799)
                     /locus_tag="KB969_000737"
     CDS             complement(18339..19799)
                     /locus_tag="KB969_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6868748.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(19789..21084)
                     /locus_tag="KB969_000738"
     CDS             complement(19789..21084)
                     /locus_tag="KB969_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6868749.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(21416..22093)
                     /locus_tag="KB969_000739"
     CDS             complement(21416..22093)
                     /locus_tag="KB969_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBB6868750.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(22123..23214)
                     /locus_tag="KB969_000740"
     CDS             complement(22123..23214)
                     /locus_tag="KB969_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBB6868751.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(23315..23749)
                     /locus_tag="KB969_000741"
     CDS             complement(23315..23749)
                     /locus_tag="KB969_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6868752.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="KB969_000742"
     CDS             complement(24333..25790)
                     /gene="ascB"
                     /locus_tag="KB969_000742"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBB6868753.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EWVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(25787..27682)
                     /locus_tag="KB969_000743"
     CDS             complement(25787..27682)
                     /locus_tag="KB969_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6868754.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(27740..29515)
                     /locus_tag="KB969_000744"
     CDS             complement(27740..29515)
                     /locus_tag="KB969_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6868755.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(29565..31061)
                     /locus_tag="KB969_000745"
     CDS             complement(29565..31061)
                     /locus_tag="KB969_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6868756.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(31255..32877)
                     /locus_tag="KB969_000746"
     CDS             complement(31255..32877)
                     /locus_tag="KB969_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6868757.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(33205..34518)
                     /locus_tag="KB969_000747"
     CDS             complement(33205..34518)
                     /locus_tag="KB969_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6868758.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(34763..34987)
                     /locus_tag="KB969_000748"
     CDS             complement(34763..34987)
                     /locus_tag="KB969_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868759.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(35007..35429)
                     /locus_tag="KB969_000749"
     CDS             complement(35007..35429)
                     /locus_tag="KB969_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBB6868760.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(35571..36281)
                     /locus_tag="KB969_000750"
     CDS             complement(35571..36281)
                     /locus_tag="KB969_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868761.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(36299..36796)
                     /locus_tag="KB969_000751"
     CDS             complement(36299..36796)
                     /locus_tag="KB969_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868762.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(36833..37285)
                     /locus_tag="KB969_000752"
     CDS             complement(36833..37285)
                     /locus_tag="KB969_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6868763.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(37420..38025)
                     /locus_tag="KB969_000753"
     CDS             complement(37420..38025)
                     /locus_tag="KB969_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6868764.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(38475..39095)
                     /locus_tag="KB969_000754"
     CDS             complement(38475..39095)
                     /locus_tag="KB969_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6868765.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(39097..39966)
                     /locus_tag="KB969_000755"
     CDS             complement(39097..39966)
                     /locus_tag="KB969_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBB6868766.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(39989..40396)
                     /locus_tag="KB969_000756"
     CDS             complement(39989..40396)
                     /locus_tag="KB969_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBB6868767.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(40415..41704)
                     /locus_tag="KB969_000757"
     CDS             complement(40415..41704)
                     /locus_tag="KB969_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6868768.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT        11760 a         8982 c         7021 g        13941 t
ORIGIN      
        1 ttttattgaa cttaaggttg attgatcaca tctaaaagcg ttgaaaataa aatggcacta
       61 gaagcagctc ctgggtcgat atgtccgatt gcacgctctc ctagatagga agctcgtcct
      121 tttttagcta ccaagacttt ggtgtgttct tttgcctggt caatgatttc ttttgttaaa
      181 ttccctgcct tcaatgcctc tgtgactggc agccaaacat ctaacatcgt tttatcgtca
      241 gcttctgcct ttcctcggct ttgaataccc gctgttccct gctcgatcac ttcgcctaat
      301 ttttcttgag aatcaataga atcgacctct tttgtcgctt tcatcatgtt catgaatgca
      361 gatccgtata acggaccaga agccccaccg actttcgata tcatcgccat agagaatact
      421 ttgaatgtat cgctgattgt ttcaggatga tcggcttgaa aagcttcttc ataagctgaa
      481 acccctcttc ccatgttatt tccatggtct ccatcgccaa tcggggtatc tagatcactg
      541 agatattgtt tgttctgatt gattgcctct gcaaattgcg tgagccattc ttggatttct
      601 tgaacggtta gtttcatatt atcacccttt tatcttgaga ttttttacca tgaaatcgtc
      661 tgtacattgc tttctaaaga atctttccat tgtgtctccg tcaagtcgat cagtgttaga
      721 gaaagacctt gcatatctag tgaggtcata aaattaccga cttttcggaa aactacattg
      781 acgcctcttt cttccaacag agctaaaaca tcattcatga acacgaactg ttccatcaaa
      841 ggcgtcccgc ccattccgtt gactagtaca cctgcttctt ttggtaaatt cgagtaatca
      901 tctaaaatct tagtaacaag ttcctttgcc agtactttag aaggctgcat cttttctcga
      961 cgatagcctg gctcaccgtg gataccaaca ccatactcga tctcatcttc tcctagttcg
     1021 aatcctggtt tccctacttc tggtacagtt gctgctcgaa gcgctagacc gatcgtctta
     1081 gttgcctgta cgaccttttc tcccagttct ttcaactcag ctagggaagc accgtttctt
     1141 gctgcatcgc ccacgatttt gtgtacaagg acagtacctg caactccgcg ttttccagca
     1201 gtatacgtac tattttcaac ggcgatatca tcatctacga tcacactttc tacttcaata
     1261 tcgtccatag cagctaattc ctttgccata tcgaagttca atgcatcccc tgtataattc
     1321 ttaacgatca gcaaaactcc ttttccacta tcggcttcct taatagccgt ctgaatctga
     1381 tctggagttg gagaagtaaa cacatcacca agcaccgctg cacttaacat cccttcccct
     1441 acaaacccgg catgggatgg ttcatgtccg cttcctccac cagaaaccaa accaacttgt
     1501 tccgctttct gattcttggc tacaacacgg gaagattcta cacgatgaac aagttctgga
     1561 tagcttttta ctaatccttc cagcatttct tcgacaatat tgcttggatc attcatgatt
     1621 tttttcaatt tattcccatc ctttctttcc ggcattttgt gcttctgtta agatttgctg
     1681 agtatcatct gttataccgg cagtgatggc tgctgcaaaa gctccttcca ctaaaggcgc
     1741 atccaccaga tgataacgtt gctgctgctc ttcttccaac atgtcttttg ccagttccga
     1801 gttcaatacc gcgctaccga tatccgcaaa aacaaaataa ctagctgcat cgcttgattc
     1861 attgactgct tctacgattt tcatcgggtc tgatccgatc tcgccattta ttccgccgag
     1921 agaaaaaatt tgcacctctt cggatttttg catctgctca atcatttctt taataccatc
     1981 tgttactttt tgactatgag aaataagcaa aatacttttt ttcacaagaa tcttcctttc
     2041 ttttacatag ttgctaacga ttggtttcgc tttcattaat gaacaattca agtatataat
     2101 aaatttctaa ttttgggaaa atatgtgtag tgcttcttga agtttgttat actttaatta
     2161 aaagagagga gtgatcgaat gattacaaca acaacgaaca gtgtagaggg aaaagccgta
     2221 gtagcttata aagggatcgt ttttggtgag gtcattactg ggatccatgc atttaaagac
     2281 ttggaggcgg ggttgcgaaa tatctttggc ggccgctcaa aaagctatga aaacgaacta
     2341 atgggtgcaa gagaagaagc acttgccgaa atggccgaac gtgcaaaagc attaggagct
     2401 gatgcgatca ttggcgtaaa aatggactat gaagtattag gcagcgacaa tggcatgctg
     2461 atggtcacat gtagtggaac agctgtctcc acgagataag taggggacat ctgttttaat
     2521 aactaaagag agatgggaca tgtagtggca ctcaagaatt agatttttca gtctaacttc
     2581 gaggtactct accttcccat cctctctttt ttatttcttt ttgcggatga ttccgtaagc
     2641 tgctgcgact aacacacccg cccctgctaa ggaataactg acagaagctg ttttttcatt
     2701 tgtttttggc aaagtctgac ttgttgattt ggatggctct gtcgtttgct gaactgtttc
     2761 tgtcgtgctt ccagaggtca ctgatttttc tcctgccgaa tgcaaaatat cttttattcg
     2821 ttggaaacta gctgctaagt cagctttttt tgcttcaaaa tcattagcaa ctgtttgtgc
     2881 ttcgctgatc tttccgtgga ttgcttgact ggccgctgtg atatccgctt gagtttgact
     2941 tagctttcca gaagctgttt gagcaacctg atttaattgc tgattgaatt cttttgcttg
     3001 ttggatcttc ccgtcaagat ctgtttggac agcttccgct tttgctttcg cttcggcaag
     3061 ctttttctca agttgtgcac ggtcatttcc cactttattt ttaagatcag ctaaatcttg
     3121 atcgattgct gcttggtctt ctttcaattt gttttttgca gcttctaatg cttcttcgag
     3181 ttcttttctt ttattttcca agtcttgcaa atgatcgatt tggtcagaag aggtagaact
     3241 atttattgat gtatcttctg aagatgaaat cgtttctcct gaattatctg tcggtacatt
     3301 ggaagtcatt tctgtttccg aggcaccgtt ttcagcacca gaagagctta tggttgttga
     3361 aggttctgtt tgagcaggtt cagaagtttc cgcaaaagct gtctgtccca ataagaaaat
     3421 actggaaaca gcaattggcc agattaacgg cttcattctt tttttcatca cttttcccat
     3481 ccttactact ttttaactaa tttcttatta taagcaaaaa tgtttggaag aaccataaac
     3541 acaacaggct gtttgtctaa aaaacggtgc atcttttatt tttttgtacg ttccgggctt
     3601 ttccatgtcc cgcttccata acctaaaatc gttttgactg ctggaatgaa agtcgtcacg
     3661 atcgttatcg cgttcactat ccagaacaaa agcatatata gtggtgcgaa aagaaggtat
     3721 ttcaattttc ttcgtcgatc atctacaatc agcgaagcta gcaactggaa aaatcctgcg
     3781 accatttcaa agcagatgaa cacaaaactg aatgtaaaag taatataaat ctgttcgtag
     3841 tttccttgat atacataatg cccgattaat ccagcaaaaa gaactacgga aatacaaaag
     3901 aatattgacc agacaatact caatgtttga tcaatgaaga tgatcgttct tccaatatgt
     3961 ttaaaaggat ggagcatcac ttttttgaaa ttcgtcagcc agacttctgt tccacctttt
     4021 gcccaacgtt ttctgtgtcg atatagcatc ttcaacgtca caggtacttc catgaaaaag
     4081 ataatctcag gagcaaaaac agataaccag tcatttaact gatgatccca agcaatactg
     4141 atgtcttctg tcgctcgatc ttgtctgaat ccgcccacat cgatcaaggc ttcttttcga
     4201 tacatcgtat ttgctccact gtacgcataa agaccaccga aaacagctga ctgtgttcgt
     4261 ttaatgatgc ccacgatact tgagaattca accgtttgag attttgcaat caatttggta
     4321 cgattttgga catccatatt tgcagtgacc gcagcaatat gtcttgcacc agggcgaatg
     4381 aaataattca catacctaat cagtgcatct ggctccggta ccgtgtctgc atcattgctt
     4441 aaaatcaatt tcccttttgc aaaggcaagt ccgatattaa acgcgtgggc ttttccttta
     4501 tttttttcga tccgaaccac acgaagatta gcgtattttt tcatcagtct agctaatatt
     4561 tctggtgttt ggtccgttga accatcgtct gtcactaata cctcatagtt gtgataattc
     4621 aatttcgtca tcaaatactc gattgtatat tcgatcacaa tttcttcatt atgggctggc
     4681 accatgatcg tgatgaacgg ttcgacactc aagggaacat ctacccattc tttttgctta
     4741 tgtttgtata aaaacacata acaccagaca ccaataaacc atacaaatcc gcctaaaatc
     4801 ggataagaaa cgagaaaaaa atacataata gacaaacaag tatctaagaa taaattacct
     4861 gtatgggtga ttgagatcat ttcagttcca ccccattttc tttatacaaa tctgcaatga
     4921 atgtcgtatc tagatttttc tcttcggaga cagaataaaa acggaccgtt tctctctctt
     4981 cttttgttcc aaaacgttcc gtatacactt cttcaagtaa ttcttgtctt tttttcaatt
     5041 tttcatcttc atattcaaaa gatttattta cttttttgta tagatttcga ttgttccacc
     5101 tagtcaatac aaatgaggta atcaggaaac tgaaaaaaat caatacaaaa aagccgatta
     5161 agaaatacag cattttcttt tctgataaaa aagcgtacaa ggaaaaatcc ttggctcttt
     5221 ctggtctcgt taatgggaaa aagacccata taaaaggaag aacaacgatc atccatccta
     5281 aaagagccac taacgtttgc caaatcttta accagtaatt accttttgaa aaatacttat
     5341 ctttcaccaa aattgatgca acttcttctc ttgttacttt tttcatatcc tcacctcacg
     5401 tttttttgtt acgacgtagg agtttaccat acatttcatt tcttttcaca taaagtgttc
     5461 ctaaattttt cctaagaaaa agaacaaaac atttctcatc agcaaatgaa aaatattttg
     5521 ttctttttat cagttgttct ttttattttt tatctcttaa ttatgttgct ctttccaata
     5581 cgacaatgct tttcattcct ctagatatcg ccgtgtacat ttgtctgcgt cttctttgct
     5641 catctccatc gttttcaaat ggatataaga ttacatgatc aaattccagt ccttttgcta
     5701 gactcaaagg aatgatttgg cagttttcta atccatatga atttttttta atcgattctt
     5761 gtagcgtttg ggtttcctct tctgtttggg tgataactgc cgctttttct ccttttagag
     5821 aaaccaaaat ctcagctagt attttcaaca attcttcaga ggatcgaaaa gagcggtatt
     5881 cgggttcttt tccttgcggt cggatcgata cgatgtcgat cttctcttga tccacagcat
     5941 aggttttgaa aagctctgtg attgctccgc tagaacggta actatttcta agatcatacc
     6001 gatggatcgg cagatggtag tcgtcgaaac aacgcataat atcagcaaaa gtagtggaag
     6061 aattaaagat tgcctgattc tcgtcaccta ctaaagtaaa gtgagttttt ggaaataatt
     6121 cgatcaatag acctaattgt gccagggtat aatcttgtac ttcatcaatc aatagatagc
     6181 gaaatgctgg tacatttacc ttttcaacaa gtaaatgacg aatagctaat ataatgactg
     6241 cttcatcaac agtacgtgtg ggttgccaag cataagctga gccatatcgt ttttcataaa
     6301 ttctttcaaa caactgatgc tcatccaccc atgccatttc ttcgatttgt ctggttattt
     6361 ttcgatattt tttttgtaaa agtttccttg cataagctac aatactttgt tccgaatcat
     6421 cagaaatcaa tttaccgaat aattccaact gcctatcttc tgtcaacgag agtacctgat
     6481 tctgcacagc aggacttttt gcttgtttca aaagatgatt cttccattcg ctcatcagtg
     6541 cctttttcgt tgcttgaagc ctatcgatca atttaggatg agcaggaact ttctcatata
     6601 ttttttcgat cgttttttta gaaaggactg tttttccatt tttagtaagt ccacggataa
     6661 aattcggatg atctaaaaac aaaggatctg attgttttag attatcgata aactttttgc
     6721 tacgcaaacg ttctgtctgc tccgatacat tttctcccgt gatacgtttg aaataagcct
     6781 cttcaccttc tatttcctct gctgaaagct gtgaaaccag ctgtatgatg gttagattca
     6841 gtggatttct ttcacctaat gatggtagga cattcgaaat atagtcgata aaccgatgat
     6901 taggtgatag aatcagcaag tcatcggatg tcatcgtatc tcgatataaa tagagcagat
     6961 acgcaatacg ctgcatgata gcagaggttt taccacttcc tgctacgcca tttaccaaga
     7021 tattttgact tttcacatcc cgaatgattg tgttttgttc cgattggatc gtagcagtga
     7081 tagccttcat ttcattggtc tcatcttggc ctaagacttc taataatacg tcatcttgaa
     7141 tagctacaga cgtatcaaaa aacttgacca aacgatctct ttccaaaaga aattgtcgtc
     7201 tttctttaat aaccgtatcg attttatttt gacgaaccgt ataagaagat ggaccaatca
     7261 tgttattgta aaaaagttcg gcaattggtg aacgccaatc ataaacaaga ttttcatctg
     7321 catcatctgt gaaatttgct gtaccgatat aaaaggattc ttttggctca ttatccagaa
     7381 agtctacaac gacttttcca aagtagggac ttttcaataa acgttcgatc tttgctagct
     7441 gattttctgc gtttttctgt ttgatattca tctgatcgat ttctctattt ttcatttcaa
     7501 tcatcgaaaa agtatccagg ttatctaagt aactgtcaaa attcaatcga agctcgccag
     7561 ccatttcttt caacgactgg tttccttcta tttttgccgt atccatcgat tcccgcagtt
     7621 cgtttttttt atcaattagc ttttgataca cgttcttcag atatgcttct tctaactgtt
     7681 tttgtgtgtt gaccatacac attctcctct ttttttaaag tggtggaacc gattagttta
     7741 cctcttttaa gagtcgaatg caagcttttt aacgagtatc atttgttagg atatatcagt
     7801 tcttcaggtc ggacagtttg atataaagaa aatgcaccat caaggttttt tacgtggtag
     7861 ccagactgct tcaagattct ttccgctaga tagctacgta atccgctatg acagctgacg
     7921 atatattctt gttggctgtc taattcattt aatcggtccc gaagttcatt caaagggata
     7981 tgtttggctt ccttgaattt gcccttttcc aattcttctg ctgttcgcac atctaataaa
     8041 atttttcctt ttgctagttc tgtcggcaat tcatgccatt gtacggtttc actaagccct
     8101 tctgcaatgt tcattgctgc atatcctagc atgtttactg gatctttggc tgagccaaat
     8161 ggcggtgcat acgtcaattc taattccggt aaatcgaaga tcgtcaaatg ccctttgatt
     8221 gctgttgcta aaatatcgat ccgtttatcc acaccttttg ccccaacacc ttgtgcacca
     8281 taaatctcgc cagtctctgg atggaagatc aacttcagta aaatatctgt tgcttctgga
     8341 taatagcttg catgatcttt tcctgataca tgaatgactt caaaagacag ttcgttttct
     8401 ttggctgttc tttcacttaa accggtggat gcggcagtca ttccaaacgt tcgtataatt
     8461 gctgttccaa taccgccttg atttcttcga gaaattccgg aaatcgtgtc cgcaacttgt
     8521 ctaccttgac gattggctgg tgaagcaaga gaaataagtg catcttttcc agtgatttgc
     8581 tgttttacaa cgatagcatc ccccaccgca taaatatcag gaatattcgt ttgataacgt
     8641 tcgtctacta ggataccccc gcgtatgcct aattcgattc cagcggtcac tgctagctgg
     8701 ttatcaggac gaacaccaat ggataaaata actaaatcag cagggatggt acgcccatca
     8761 tccagtcgca atcgtttccc gtggtcttca aatccagcga cagcatgaga agtaatcact
     8821 tctactcctt gatgagacaa ttctttttct ataaaagctg ccatttcttc atccagtgtt
     8881 ggaagaatat gtggtgcttg ttcgatcacc atgacttcta aacctcttct ttttaggttt
     8941 tctgccattt ccaatccgat gaatcctgca ccaacgatca cggcacgctt tggctgtttt
     9001 tctaatgcat gcatcacttt atcgatatct ggtacatttc taatagaaaa aacattgtcg
     9061 gcttctgtta tccctggaat cgatggaaca actggttttg caccaggaga taaaaccaat
     9121 gcatcgtact gttcaatgtg tttttgaccc tcatgtacga cttctaccgt tttgttttcg
     9181 ggaaagatgg ctgtcacttc atgatttgga cgcacatcta aacaaaaacg agcggataat
     9241 gattctggcg tttggacaag aagattttcc cgttcactga tttctcccga aagataataa
     9301 ggcaagccgc aatttgcaaa agaaacatac ggtccttttt caaaaacaac gatttctgca
     9361 tcttccatta atcggcgaag ccgtgtagca gcagacattc cacctgctac acctccgaca
     9421 ataacgattt tcatcttatt tccctcctac tgttcgatca aaccattgat tcatgccacc
     9481 acgtacattc actacatcat aaccagattt ctttaattct ttagctgctt gtttactcct
     9541 catccctgat tgacaaatca catagacggt cttttctttg tctccatcat atctgtttat
     9601 actttgtaat ggaacatttt tagctccttt tatatgcccg ccccggtatt ctgcaggtgt
     9661 tctaacatca agtaacgctg gattttccaa aagcttttcc tttaattctg ggactgttat
     9721 cgattttatt gattgaaata gcaaattcat tttctgcacc tcatttacat ttttataaat
     9781 acctcatggg gtatattaaa caggagcttt attaatatgt caaccagaat gactcttcat
     9841 ttttttcact actttttata tttgcataaa ataccgataa ggggtattat ctaattataa
     9901 aaatagagga gaatgtgtta tggagattga taataaaaat atcctgaacc gtttgaaacg
     9961 tacagaggga caaattcgtg gtatccaaaa aatgatcgaa gacgaaaaag aatgtatgga
    10021 tgtcatcact caattaagcg ctgttcgttc tagtattgat cgcgtaatgg gcatgatcgt
    10081 tgcagataat ctgaaaaatt gctttgagaa acctgatagt aatccagaag aacaagcggc
    10141 taaactagaa caagcgatca agatgattat taaaaagtaa aggaatgatt tcaatgaaag
    10201 tcgttttcca tattgatgaa ttagaaaaat ggtcagaaac agggaaaaac gtaaaaaacc
    10261 tgataaaagc ttctccagaa acgacgattg tcgtatctgt aaatggcatc gcgattaccg
    10321 gttatctaga ctctgccaat gcagaattct tagatttgca aggagtcgtt tttcacgctt
    10381 gcgccaatgc tatgcgtgct aatcatattt cagaaagttc tttacctgaa caagtaatcg
    10441 ttgtaccagc aggtgtcctt gatttagttg aactgcaatc ccaaggttat gcttatatca
    10501 agccttagtc agtagaggtt gcgacagaag tgatcagctt caagaaattt cggcttattt
    10561 ttcgaagaag ctacttctgg aaaaccgtga atcaaaggtt gtgaaaacgc tgtcctgcat
    10621 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcgtttg gttgggctta
    10681 ttaccgcaga tgcaagcttt tgaacaccgt ttaaggaaga ggttgtgaaa tcagcggttt
    10741 gacctaagta ttagagaaaa aaacgggaaa atagctcctc atattttgcc gttttttgag
    10801 ctaataccga aggtcagctg attgaacacc gtttaaggaa gagattgtga aaaagtcgct
    10861 tagtttcgag tattaagaaa aattttgtga aaatggattt ctacattttt gcataaattt
    10921 ggcttaatac cgagaaactg gcttttgaat accgtttaag gaagaggttg taaaatcagc
    10981 ggtttgacct gagtattaga gaaacaaacg gaaaaatagc tgctcatatt ttgccgtttt
    11041 ttgagctaat accgaaggtc agctgattga acaccgttta ccaagaggtt gtgagcctac
    11101 catttaactc cgaatcacaa gaaataattt caaaaacaac ttctcctgtt tttggttcgg
    11161 ttggcttatt atcgagaagt agctactggg agtctattta tcaaaaaaag gaatgcgaca
    11221 taggtcacac ccctttttta ttttctttga aacatctttc ggtactcgac agcatacaag
    11281 acaaaagatt gtaaaagacc gtaagtgatg acggcaaaaa tgactctcac ccacagcgtt
    11341 ggtaattctg ggaaaagcag caaaaggatc atgccaacat agatgacagc agtcgctact
    11401 ttgccatacc acttcgctcc acttaatttg atatttttag atagcccgat taatccagct
    11461 acaaacataa agccttcttt tatcaagaat agaccaaaca acagccaaag ccacggtcga
    11521 taccatgcca tagacaaaat cagaaaaagt tgtgtcaatt tatctgcaaa cggatcaagc
    11581 accttcccta agtctgttac ctgattatat ctccgagcaa tgaccccgtc tagataatca
    11641 gacaaacctg agacaacaat gaccgctcct gctatataaa atgactgtct cagcacaaaa
    11701 taaagataaa tcggcagcaa aaaaatacgg aatatcgata aaagattcgg aatcgtttgt
    11761 atttctttac gccagtctgt gcttaatttc attttatcgc cctacctcct cagcactctt
    11821 ttctttttat tttagcttac acggggaata aaaccaatga tttcactgtt tttatttttc
    11881 tttacagaca ctgatattat gagctaattt gagataatca cttgctgttt tcatcgttta
    11941 ctcttctttc ttcctgtcgt ttgcgcattt cttttactag tactttatga gctttttttg
    12001 atcctcgctc taggtcacgc tgccgtttac gtgttttata atcgataaac agactgtcta
    12061 aatcgtaacc tgtcgggtac agatcttctg ctgaacgcac cagacgaaca cgctgacgag
    12121 gcacgtggat tatttttttg tctaaatata catcaatcgt atcttcacct atatcttcat
    12181 aaactaacgc ttctttttgg tattcattga caaatatccg atcacctttt gcaaagagct
    12241 gacgttcttt tttattctcc ttcctatttg taactgctgt cttaggaaga aattcttttt
    12301 tctgtgtccg ataggctttt tccgccaagt aacgctctgc ttgatggatc aatttcatcg
    12361 acatatccat tttatgagca atccacaaag cttggctttc tcctgtttct tccaacccgc
    12421 aactgatatt taggacgaag tgcttcccga tcgaaagcca tagcagccgg cacaaaatct
    12481 tcatgatctc cggcgaattt cttgatttct ccataatggg tcgtggcaat gatcaatgcc
    12541 ccttgctcat acatagattc catgattgcg atcgctagtg cagccccttc atttggctct
    12601 gttccactgc caatctcatc taaaagtacc aacgtattcc tttttatctt tttcaaaata
    12661 gcagcgatgt tttgcatatg accagaaaat gtactcaacg cattttctaa attttggtgg
    12721 tcaccgacat cgacgaaaat ctcatcaaag acagcaagct ctgtcccttc ttttgccgga
    12781 acttgcatac cgaacatcgc catcaaagtc aataaaccga ctgtcttcaa cacgactgtt
    12841 ttgcctccgg catttgctcc ggtgataatc aagcctcgat agtctttacc gatttcaaca
    12901 tccaatggta ccgcatgctc aggtaaaaat ggatgtctgc cttgcttgat aatgatatgt
    12961 tccgatttat tgattctagg tgtgcttcca ttgatttctc ggctaaattt tgcccgagca
    13021 aagatgatat ctaacaccgt gatcgtttcg atcaataaat cgatcacttc ttcgttttct
    13081 gcgatagcac cagtcaatgc cgccaggact tgatattctt cactgatttc ttcagctttt
    13141 aacaactgat agtgttcatt caatttagaa atcacagttg gttcaataaa aaccgtcgtt
    13201 cttttatttg attcatcgat aatcgttcca tctattttat ttttatagct ggctttgata
    13261 ggaatcgtat agtattcgcc tttttgaaca atcattgctt cttggatcat ttctttgttt
    13321 ttcggatgac gcaagaattt cagtaatttt gactggattt ctttttcgat tagttgtaat
    13381 tgtttgcgta ctttacgcaa attacgtgac gcgtcgtcac tgactttatt attttttatt
    13441 ttctggtcaa tcaactcttc tacatttatc aaatcaggaa gatgtttgct ataagcaaac
    13501 aacaagggtg tctggtattg attcttatca aaaaactttg tgatcatccg actgcttcta
    13561 agaaaatccg catattcgat caaatcggtt ggctgcagaa tcaacccttt tttgacttgt
    13621 tctgtcagtg catcgatcct cggcaacccc ataaatggaa catgctgact gctttctaag
    13681 atcaagcgtg cttctcttgt ttcttcttga cgatccaaga cagtttgtag gtttgtcgag
    13741 accgtcatat cgctgattcg ttttttgcta tagtttccaa ttgctcttgc ttggatttcc
    13801 tttttgatcc gatcaaattg taattgacta atcatttcgt tgtccatatt ctctcctttt
    13861 cttgaagaga tacctgtccc aaaataaata agggcctaga gataaataaa aggatagaac
    13921 acagcttaaa aaagtcatgt cctatcctta ttagaataca aagatattgt tttcctgaca
    13981 ggtaccgttt cataagcaca ccaaataaac tttgtttatt ggctattcga cttactgatt
    14041 agataccagc tacactcaca aaacataccc cattcttcta ggtcttattt attttccact
    14101 taactatagc aagacacatt ttggttgtca aactttagta tgttttatag atttacacca
    14161 ttaatgaata gacacctacc gcgataattg ctccgatcat tggacctgcg attggtaccc
    14221 atgaatatgc ccaatctgaa gttcctttat tagctattgg caataccgca tgtgctaatc
    14281 gaggaccaaa gtcccgagca gggttgattg catatcctgt tggccctcct aatgaaagac
    14341 cgatggctaa gatcaatcca cctacagcga atacgttcgt tccaggtgca aattcgtttt
    14401 gtccaaaagc tagcaaccca agaactaata caaatgtacc aattaattct gtgatcacat
    14461 ttgctggata attccgtata gcaggacctg ttgcaaacgt tcctaaaatc gcgctttcat
    14521 ctttcgttgc attccaatgt ggcaaataag aaagccaaac aagaatggcc cctgcaaaag
    14581 ctcctaaaac ttgcgcaatg atgaaaggaa cgacaagatt ccaactaatt gcccctgtca
    14641 tcgccatagc tagagagact gcaggattca aatgagctgg gcccatgaat ccagaaatat
    14701 agacagccat tgttacagcg agtccccaac caaatgcgat gacaatccag ccagaagcct
    14761 gtgctttact tttgtttaaa ttcacagccg cacacacacc atctccaagc aaaactagga
    14821 tcagtgtccc aataaactcc cccatgattt gagtcatatc actgttcatt tatttctccc
    14881 cctttagttc ccgcagatct gattctgcaa tcaatgcttc taaacgttta gtctgttgcg
    14941 ccttctcctc ttctgtccat tcaaaatatc cagcaattgc atcgatcaca ggttgcttga
    15001 tctcatcaag ctgatctcgt tcaaacaaca gatgatttgt acgacgaatg agataatcgc
    15061 ctggggccaa aaccatttct tcttctaaac cataacgtaa ccgagctgac tcagcgagac
    15121 tcaaaccagg ataaggtgcc atttcttttg ctaattcaaa gatacgtcgg gcattagtcc
    15181 cgtaaaaatc agcgatataa gtagcatctt cttcctctaa accggctgct actccttctt
    15241 ttgctaattc tgtcactgtt tcttctaatt tagttggatc gaagtttcca cctgaaatct
    15301 gatatttttt agagtcgatt tctttcgtct ctattccgta ttcttctttt aataattggc
    15361 gtatcaatcg caaagctcct tctgccatct tacggtaatc ggtgattttc ccaccagata
    15421 aagtcagcaa accatctggt tctctttcta aagaactacc tctggaaatc gtagaaggtg
    15481 ctttttcatc acggctgttt tccaaatggt tcaacacgtc ttctacttca gcacgagaaa
    15541 ctttgttttc cttatattca cttactgtat cgacaacttt attgaagctc ttgtctgaaa
    15601 tcgatccatt atctccacca ttgtaatcag aaccagaatt accaatcaac agtggacgaa
    15661 gtcctgccca gcttgcttcg atatcattca atgtgatatt tgcttctgga tagcgatgat
    15721 tgatcacatc caatagataa tctacatctt cttgtgtgac tttcggatcc gtaaaatctc
    15781 cttggtaatc cgtatctgtc gtaccaaagt aagtcttgtt ttctcttgga atagcaaaaa
    15841 ccatccgccc atcttgcttt cctgtatcga agtatgtggg ttgcggtaca ggcagttttt
    15901 tcgcatctac aactaaatgg atccctttag ttggacgcat tttaggagag actggacgcg
    15961 taaaattcaa gtttcgtact ttatctaccc aaggaccact cgtattgatc actaattttg
    16021 ctttgatttc gatcacttca tctgtcagca ggtcacgagc tttgacgcca acgatttgat
    16081 cgccatcata taaaaagcca accgctttca ttttacttac tagataagcc ccatcttcgg
    16141 cagccttttt gatattatca atcactaaac gggcatcatt gttgcggaaa tctagataga
    16201 cacccgcgcc ttttagccct tcttttttca aaaacggttc tctttccaat acttcttctg
    16261 gtgtcagcgt ataattctca tatttggttc ctgtcacatt tgccagtttg tcataaaggt
    16321 ccattgctac tttgaccgag aacatattga aggttgttgc tccttcgccc tcatagattg
    16381 gcaaaagcat tggatctggt tttgggatgt gtggggcaat actttgtacg actgcacgtt
    16441 caccaactgt gtcagctact acttccacat caaatgtctt cagataacga ataccgccat
    16501 gaacaagttt ggtcgagcga gaggaagtcc cttctgcaaa atcctgcatt tcgatcaatc
    16561 ctgttttgat tcctgatgct gctgactgga ctgccacacc ggcaccagtg attccgccac
    16621 cgatgatcaa cagatccaat tcttcttgct gcattttttg aatgctatct tgtcttgtct
    16681 tgtttgaaaa catatggatt tcctccttat tcaaatgctt gggtagcttt tactgctttt
    16741 ttccaaccgt tgtaaagttt ttctcggcgc tcttcctcca tttgaacttc aaatagcttg
    16801 ccagcttcat aaaattcgcg gatctcgtct gtatctttcc aataaccgac agctaatcct
    16861 gctaaaaatg ctgcccctag cgccgttgtt tccaagtttt ctgctcgttg gatcggtaca
    16921 ttcaagatat ctgtttggaa ttgcatcaga tattcattgt ttgctgcacc gccatctact
    16981 ttcaatacag gaatcttgat tccagtgtca tcttgcatcg tatcgatgat atctctcact
    17041 tgataagcaa tcgactgtaa agtagcttta atgatatctt cttttgtcgt accacgtgtc
    17101 aagccaaaca tagcccctcg tgctgcctga tcccaataag gagcacctag cccaacgaat
    17161 gcaggaacaa cataaacctc atcttcgctt gtagagcgtt tcgctgcgtc ttctgaatcg
    17221 ctagcttttt gcaacatttg aagtccatct ctcagccatt gaatcgaaga accagccaca
    17281 aaaatacttc cttctaaagc atagtaaacc tttccattta tgccgtaacc aattgtcgtc
    17341 aataaattat ttttggataa ttgcggtttt tcaccggtat tcatgacaat aaatgaacct
    17401 gtaccataag tattcttgac catgcctggt tcgaatgcca tttgtccgaa taatgcggct
    17461 tgctggtctc ctgccatccc tgaaattggt gcttcgcttc cataaaaatg ataaccttgc
    17521 gtataaccat aaacttctga gttagaagtg acttttggta acatcactcg aggaatattt
    17581 agtaaatcta aaatctcctg atcccaatct agctgatgga tattgaacaa catcgtccga
    17641 ctggcattcg agtaatcagt aacatgtgct tgtccatcgg tcagtttcca tactaaccaa
    17701 gaatcgatcg ttccaaacat caattcgcct ttttcagctc gttcttgcgc gccttctaca
    17761 tgatcaagaa tccagcgtat cttcgttgct gagaaatagg catcgatcac taaccctgtt
    17821 ttttcgtgga aaaattcttg atagccttca ttttttaagt tatctgcaat tccagctgac
    17881 tgtctggatt gccaaacaac tgcatgatag attggacgtc ctgtatcttt ttcccatatt
    17941 actgttgttt cacgctggtt cgttatgcca atcccagcaa tctgatttgg tttgatccct
    18001 gattcgatga acgctccggc aataactgac tgtacagaat tccagatttc atttgcatca
    18061 tgttccaccc aactttcttg cgggaaatat tgcgtgaact ctttttgaga actgccgatg
    18121 tgtcttcctt tcttgtcaaa gataattgct cgtgagctag ttgtaccttg gtcaatcgcc
    18181 atgatatacg ttgattctgt cattgtgatt ccctccatta tatgcaaacg ctttctttaa
    18241 ctactcttat catactactg ttttaaaaaa agaaactgtc aaaattttat tctttttttc
    18301 tttttttgac agttttttat tatgaagcta ttttttaatc aattcttttc ttttttcagc
    18361 gtctctattc ttcttttcaa tcgaataatg tcgtaaggtg acgcaaattc tgacagataa
    18421 tattcacact gttttttgtt tctctggcaa aatgtgatca ccaaatcata ttctttacct
    18481 tcttcataac ttccaatctc aataccgccg attcccctca gttctctgat cagatattgt
    18541 tgaaaagcaa tacgataaat cggcagactt tctaaatcga ttccaatcac tactggtttt
    18601 gcaatataaa aatcgatcat caaaagaaca ttggcatact ggatcatcag gtaactaagc
    18661 tcactatctt cagctctttt cctcggcaat tgctgcaccg ctgtttcctg taatttcgcc
    18721 agtaactgtg ttaaggaatg cccgagcatt ttctgctgct gttccaaaag ccgatcacgc
    18781 tcatagactt cgatctttcc aacaaagaaa aaccattcat tgttgatctg ggaaatttgg
    18841 tagcctactg ccttttcttc tttgattttc aaacgacgag gacgataatg ccataacatc
    18901 gtttcccgaa tgtaagtatc taaaacagcg gttggtaact ttttgctccg tgtcaaatca
    18961 tactgataaa atatttcttc gtctactatc gaaaaagaaa caaaaaagct gtaaaacatc
    19021 attgtttcgt atacattcag ttctgctgct gttcgactaa gatgcatcac gatgattgga
    19081 tcgattgctt gataaagccg gtccgactga tagagtaatt tcttttcttt caaagttgcg
    19141 tacgtacttt tttcattcaa tagtcttttt ttcgtaatcc cgagccagca agcaatctgt
    19201 gcttctgctg atgccgtaaa cgttgtttct aatacacggt ccaatcctag aatgaacggt
    19261 cttttttctg gtgtattttg caaaaaaagc ggtcgctgat cttccgggat atattggaat
    19321 agttcataat aaaaatatcg tatctgtagc tcttctccgt ataattgacc gtttttgatt
    19381 tgtaatccaa attcctctaa gagctggttc aattctttga tctttcgaaa aacagaagac
    19441 tcactgatat taaacgctgt cgctaatcga acgatggata cttgctgatg ttctaataaa
    19501 tagacgagca tcttaaactt caagctttcc tgcaataaaa acaatagaat tttttccaaa
    19561 cttacatctt cgtccaacac aagcagcgcc tgatactcat ttcgctgtac ttctactttt
    19621 ttttccatca ttcggccaat caattcaata tcttccaaat attgatcaaa cgaggctttt
    19681 gacagttgga catgctctct caaaccattg atagaggctg ttcccccttg cagaacaagg
    19741 tttcgcaaaa tcaggatctg taactgctct tttctttcta ataatgcttc aatcttcata
    19801 ggcagtattc gccacctttg accacaccat atctggcaca cggtattctg gctggaaaaa
    19861 tagctcatgt tcttctaact gttcaaacgt ccatccttct tctactgcaa ttgtcagttg
    19921 gtcaagaagg tggaacatct cttttttgct ttggagctgt gctccaagaa tctttttttc
    19981 agaatcaaat agaaatttga gtttaacttt gctttgattt attgctgtaa gcttgtagtc
    20041 tacgtatcct gtttcaattt tttggggata aaaaatgctc tcttcttctg tcaaacctac
    20101 gcttcctaag aaatagccaa accactgatt gccgactgga cgataggttc cctgatcctt
    20161 tgtctgtgag ccactaattg tcttgctgac atttcgtgct gtacggacag cgttatttac
    20221 tagagaaaca tacatttttt catttgttgg acgaaaagtt acttggatcg catcgccaat
    20281 cgcataaacg tctttttgag acgtttgcaa gtagtcatct acccagatcg ttccatcatc
    20341 attcaatgtt aattgttctt cccacatctg attgtcggga cgagaatgat tagccagcaa
    20401 aacaagatca tagttctcct ttcttttttc cgtctctaca atagcggttt cattttcggt
    20461 caaagacaca acttgttctt ctaaaaaaag tgaaagccct tgatttttca tttcctttac
    20521 taacggttct gtcatttcag gatctagata acgaaaaaga attgactttc ggctttcgta
    20581 aagatggatt tgtttttttc ttgatgccaa cccttcagct atttcgattc ctgcttgtcc
    20641 tgcaccaata attgcaattt tctttgcatt catgatcttt tgctgaagag ccgttacgtt
    20701 ttgtatcttt ttaactgggt gaataagcgt tgattctgca gaaatatttc gaaacttttg
    20761 atttgaacca gtcgctagaa tcaaacgatc aaaatccaat ttttttcctc ctgctaaaac
    20821 gacttttttt tctttcaatc ctattactgt cttttctgtg taaacatgga ttcgatagcg
    20881 gtcagtcagt tcttctttcg tgatccaaga aagttgtttt tcactggtaa cctttccttt
    20941 taatatcaaa ttgaacccgc tgggaatcca tcctaacttc gattgctttt caatcaaata
    21001 tatttcactt gttggcatca attggcgaag ataaatagcc gcatgaatcc ctgcaaacga
    21061 cccgccgaca attacaatgt tcatctgcat tcctctttct tataaggtgt tctactgcta
    21121 acttctcaat cagaaaacac agtattcata actcgctttc aaccttatga tacatagcga
    21181 tgcagcagaa tcaaccctct ccatcatacc gtgttctagg tctgcttctc aataatgtac
    21241 tagtggacct aattgaagag tatcatttct gaagagatgt ttcaaaaaat gtactcttat
    21301 aaaagaaaaa aactcgcctt ttacgtacct ctgtccaaat aggaaacaga aaagaacgaa
    21361 aagacgagtt ttagcgtgtg taatgtaata gttagaatag acacatcatt tatttttaat
    21421 tctttaatgc ttcaacaact gcttcgccta attgatgagc agattgagga ttttgccctg
    21481 taagaagccg cccatcaatt tgaaccactt ctgaaaaagc tgctccagac tgatagtttg
    21541 ctcctttttc tttcaaagca tcttctgcta agaatggtac ttcattcgtt gtaccatttg
    21601 cttcctcttc ttcattactg aacccagtca ctgtacgtcc agctaaaata gattttccag
    21661 actcatctgt aactggcaac aatcctacaa caccgtgaca aacagctgag accagccctt
    21721 catttcgata gatttgtgaa gcgactttcc caagatctat tgcttctgga aaatcccaca
    21781 ttgttccgtg gccaccagca taataaaccg ctgcataatc atttgcatcc acatcatcag
    21841 gacgtaaggt atttcccaag gcccgatttc tgaaatcttc atcttcataa taggcccaat
    21901 cgatttcatc catattcaaa acactttgcg gttctaaagg tacatatccg cctttaggac
    21961 tgacaaaatc tgcatcgatc ccatttttta ctaatacatc ataaaaatga gtcagttcac
    22021 ttaaccacaa acctgtagga cgctcgatct tttcgtactt ttctacattt gttaatacga
    22081 tcaatacttt cattttccca tcctctttct ataaaaattg cgttattgat aacgtgcttt
    22141 caagaaatta tataatgggc ttggcaaata aagctcttta tatgcttttt caaaaggttt
    22201 cgttacaaat tcatcctcac ggttttccaa taatttctct gcccagtcag gatcgacgat
    22261 catttgctgt ccaattgctg caagttctgc atatttcaat acctgctcta catcttcgcg
    22321 attgcggatc ccaccgacac caactaaagg gatctttcct tgaatcgtgt tatggaccac
    22381 ttcaagaatc gatttatcgt tgtatttatc agaacgagct attcgatcat acatatttaa
    22441 tgaaacatgc agataatcta gttttgactc acgtaatcgt tcaagaagcc agatcgtgtc
    22501 ttcaaaacgg atacctggtg tttcatattc ttctggtgag aaacgatacc ctacgatgaa
    22561 tggtttttta gcatattgtt caaccgctga gaaaaccgtt gttaataatt cttcaataaa
    22621 acgataacga ttttccaagc taccgcccca ttgatcctct cgtctattcg aatgcggaga
    22681 gaaaaattgt tggatcaaat acgtatttgc tccatgcaac tcgattccat caaatcctga
    22741 ttcaatcgct ctacgtgtgg ctttgccaaa tgcttggatt gtttcaacga tttcttcttc
    22801 actcattgct cgtggtgttt ccgcatcagg acgttttgct gcaactgcac ttgcagatac
    22861 aggctgttct ccagataaag ttgctcgact tgtcattcgt ccaccgtgga aaatctgaat
    22921 aatcgctttt gcgccttctc cttggattgc tttcgctagc tcacttaatc gaggaatcat
    22981 ttcatcatga gcgatgctga gttcacctgg ccagcctttt ccgatatctt ggacatttgc
    23041 agcaccagta ataacagcac caagaccttt agaacgttgt ttataataag tgatctcatc
    23101 ttcggtgatc actccattga aaaagctgag ttgtgtcgtc ataggcgaca gcatcaatcg
    23161 gttcttcaat tgaactcctg aaggtaaagt aattgattga tcaaattgtg acattgtcat
    23221 tcctcccata attcgctctg attaacctat cgagaatcat ctatcattaa accactcgat
    23281 tagttgtaca tgcaactaat ttgcttaaaa aattttattt tttttgtaac ttatctgttg
    23341 catcattcat tgtctgggct aattctttac ttgcttcatt tcccaaaact gctttgtatg
    23401 actgatgaag ttcttcccag ctaccatcga cttccttagc aaattggcgt ccttgttctg
    23461 taagataaac taatgacaag cgaccttcgc taactgtttt gacgtatcct ttatattcta
    23521 atttttcaac aaaacgagca atcgttgatg gggcggaata gagcatttgt gcaatatctt
    23581 tttgtggtat tccatctttt tcttttaata tcaataaaat aaaaccataa gttggtgcca
    23641 gacctgtcct tctaaacgct tcatcagcta atttattcaa catgcgatct agctttttca
    23701 cgctaaagaa aagacattca tctaacgctt tttcaattgg cttttccatt tcatcccctc
    23761 cattggcgta catatcatag tatgattttt attttttgtc aaaaaacacg gaataatgtc
    23821 cgcctcctct gtctagattt gaaaaaaaga agtagccatc ttcaaagaat ttcggcttgt
    23881 tttcgacaaa actccttctg gaacaccgtg aatcagaggt tgtgaaaaag tcgtttagtt
    23941 ttgagtatga agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt
    24001 aataccgaaa aactggcttt tgaacaccgt ttatatcaga ggttgtgaaa aagccgtcct
    24061 gcatcaagta ataagaacag ccaaacaaaa atagttcctc atattttgtc gttttttgag
    24121 ctaatgccga tggtcagctg attgtacacc gtttattgag aggtcgtgag cctgccgttg
    24181 aactccgagt cacaaggagc aatttcaaaa aacagcttct catgttttat gactatggtg
    24241 acttgtgatc gaggagttgg caggagaata ctgtttattc gtaaagaagg ggctgtgaca
    24301 agacttttgt cacagtccct tatttccttt tattatagga tttcgccatt tgattggatg
    24361 acttgtctgt accaatcaaa tgattttttc tttaaccgtt tctttgtgcc attcccttcg
    24421 tcatcttgat caacatagat atatccataa cgttttgaca tttgtgaagt agaagcgctg
    24481 acgatatcaa tgcagcccca cgacgtataa ccaaataaat ctactccatc tttgatagct
    24541 tccttcatct gctcaatatg ctgcttcaaa tagtcaatgc ggtaatcgtc ttgaacggtt
    24601 ccatcttctt ctactttgtc tatagctccg agtccgtttt cagctatgaa cagtggtttt
    24661 tgatacctat catataattg attcaaagca attctcaaac ccttaggatc aatctgccag
    24721 ccccattcac ttgatggaag atacggattt ttaattcctc cagttattaa gtttccttgg
    24781 acccattccc aattttctgg atgagcactg actgcactag acatgtagta gctaaaagaa
    24841 acaaaatcaa cagggtaggc tgctaagatt tcttcatcac ctacttctat ttttaagttg
    24901 acaccttttt cttcaaacat tcgttgcgta tacgctggat aatatcctct tgcttgaaca
    24961 tcactaaaga acaaagaagt tctttgctgc tcaattgttt tttgaatatc atccggatca
    25021 caagaatacg gaacaagaag ctgatagctg atcatacaac cgacttgtga acctttgata
    25081 atttcatgac aagcttttgt agctaaagca cttgctataa actgatggtg tgcaccttgg
    25141 tatttcgctt gttccaaatg gggatggttt tcttcaatta ctcctacgct aacaaaaggg
    25201 tgatgtttta cacagttgat ctcattgaaa gtcatccaat attttacttt atttttatag
    25261 cgtttgaata ctgtttcagc gaaacgaacg taaaactgaa taagctttcg attaggccat
    25321 ccaccatatt ctgtaaccaa atataacggc atttcataat gggaaagaga aacgactggc
    25381 tcaatcccat attttagaca ttcgtcaaac acttgatcat aaaaaaataa tcccgcttca
    25441 ttgggtgttt cttcatcacc atgaggaaaa attcttgtcc atgcgataga catccgatag
    25501 catttaaaac ccatttcagc aaataaacgg atgtcttctt taaagtgatg atagaaatca
    25561 tttccgtgtc ttttaggata ataatacttg ctgttgggat cctgcgccgc ttttacttgc
    25621 tgatgcgtca tcatatgcca ttgatctgtc catttttctt taggtaaatc gctgtcgaat
    25681 gtatacacat cagacacaga taatcctttt tcatctacat cccatgcacc ttcacattga
    25741 ttggccgctg tcgctccgcc ccataaaaat ccttctggaa attttttcat atcgatcccc
    25801 ctaaacttgc tagttttctt gtttgattat ttttcttatg actagtaatg atatttttga
    25861 atctactact atttgtaaca ataaccattg tggtcggatc atatccctct ttgattaatt
    25921 cttgcaaatc tacttccatc aataaatcgc ctttacgtac tttttttcca tcagatactg
    25981 cactttgaaa gtatttgcca tttaaattca ctgtatcaat accgatatgg atcagtatct
    26041 ctgctccttc ttcactgact accccaattg catgtttcgt tggaaaaact gttgaaactt
    26101 ccccgtttac agaactgtag atttttccgt ccgttggaat gatcgcaaac ccttctccta
    26161 aagatccact agcaaatgtt ggatcgttta cttcagataa atcaattatt tcacctgctg
    26221 caggagtact taacactata tcctttgagg attcttcttc gatttcatcc ttgtagccga
    26281 aaagaaaagt tagcatacag gaactgatca tcgctaagaa ataactagca actagccaaa
    26341 caaatccttc accaatataa atcgggaaag acaaaatact tcttgtagca actgccaaag
    26401 caccggctcc tgcggcacca gctactccac caaatatagc tccacatata caagcaatgt
    26461 aaaatggtcg tttatattta agagtcacac cataaacagc aggttcagtg attccaaata
    26521 atgctgtgat aaatgcagat aaagataaac tttttacttt cttatttttc gttttcaaaa
    26581 ataccccaag tactgctcct gcttgcgcag ctacggcagt catacatgct ggacctagcg
    26641 tatcacgacc gtagaaagaa agattgttgg tcattactgg tacaagtccc caatgtaacc
    26701 caaaaatcac taacacttgc caaaatccgc cgataacagc accagataaa acagggctaa
    26761 agttataaac agctaaatat ccagctgcaa tcagctgact tgcataatct gcaattggac
    26821 ctacaactaa taaaataatt gggaccatca cgatgataca aatgaatggt gtcaataaat
    26881 ttcgaatact ttcgtgcaag cttttgcgaa tcttaggctc aatataagaa agaacccata
    26941 cagctaaaat tgctggaata accgtacttg tataccttgc tagaatcacg ggcatcccta
    27001 gaaatcgcaa ggttatgcta tcactatatg cactgacaat cgtaggataa acgagagctg
    27061 ctgcaataac catagcgatg aaacgatctg tattgaactt ttttgcagca gtatatgcca
    27121 aaaatatagg caagaaatag aaaaatgcat cagctgctgc attcaaaatg atataagttc
    27181 ctgattcagt agttaataaa ttcaaactcg tacataaggc gagtactcct ttgatcaaac
    27241 cacttcctgc caagacgcct aaagtcgggg caaaaacagc ggcgatcatg tctataaaag
    27301 agtttaaaat gccttttttc tcagttcctc tctttccact agatgcatca tcttctagtt
    27361 tcatttgttt ggataatacg tcatacactt catttactgc atttcctact acgacttgaa
    27421 acattcctcc agcttcgact acagtgatca caccttctag ttgctctacc ttctccttat
    27481 ctgccttctt attatctttt agggtaaagc gtaaccttgt tgcacaatgg taaacattgc
    27541 tgacattttc ttcgcctccg acaaatcgga caatatcttt cgctaattgt gaatagtcca
    27601 tttttacttc ccccttgtta attaatgccg tagcaatcct tcttacaaga taagtatagt
    27661 tcttagaaaa cggtttctcc attcaattag taccccttct aatagcgaac gaaactgtac
    27721 aatagtgtgt atggtttact tagccgagca aatcactcac tgcttgaaag aaaacaagta
    27781 tatcgtttct cttatagtca aaggagacaa aaaaaacacg cttgatcttc ctttgctgat
    27841 gtataagtgg tatctcaagc tgatactctg tgatttttgt ttctacttgg cttttgataa
    27901 gacagcacaa caaagtctcg gcatttaacg gaagcataac taggtcagaa ctaggagaga
    27961 ttagttgctg aatggaatct atctttttat ggatttttat ttgattttct tctttgtagt
    28021 aatgatcaag cagttttgtt ttcttttttt cttcaactat ggtcagcttt tcacgcaaaa
    28081 tctgataaat ctcccaagat tcaaactcat ctagaacact aggtagataa atcaaatcat
    28141 cccactcaaa aataagctct tgctcagtag tcaaaattgc atcatattcc gttattttgt
    28201 ttgattgatt tttgaaaaga tacactggtt ctatccggca ttctttgatc cacatgttca
    28261 tactttgttg aatctgtttt tttagtgtat tcaaaatact aattggctgg ttactaacaa
    28321 tcagtatctc cccttgtttt cgaaaaggat tcaacgcttc ggcaagatac aaaacaaaat
    28381 aagcgctttc agctaaattg ggacgtaatt gaaaatgtat tgggaagaaa cgccgaatta
    28441 aataaatttc taaaggataa cgggagatga tcttttgtac aaaatgattc atggtattat
    28501 gtccggcatc catcctcgtt ttcatttgtt tgatatgggt tagcaaaaat tctgtttcat
    28561 ggaacaataa cgaaacagga agatctaaaa aacgaataat cgtttgctca aatgctctta
    28621 gattcttctc tatttctttg tttttttcat cattaatcat caaataattt aactctaata
    28681 gtcgattttc aattgcttgt ttttcttgat tggaaaaaga atagggtagt tctgatgata
    28741 acttttttgt gagggtctct accatcggaa taaataatgt atacctgttt gttttttcta
    28801 aaagttcttc tcttcgaaga atggtcaaaa cgagataccg agaaaatcgt atgaagtcct
    28861 ctcctgaaac aatataatta tatgatataa gaacctcttt taatgtcttt tggacagtcg
    28921 gcatgatatt ggaaaaaatt gtactgattt gttgaggaaa ccttgcgtgt tggatcaccg
    28981 tttctgttcc aacaagagat aagaaaattc tttttgaatt ttcttcagca atgattttta
    29041 gtccttttgt cgacgaaact tccagttcta atttaggatt gcgctcgatc caacgcaaaa
    29101 tcgtttttat ttgtaatgat acggctgttt ttgaaagaaa gaaaatgtct gctatctttt
    29161 gcatactgac ataccctttt tgaaacaata agtacgtcac aatagttgaa gctcggaaat
    29221 ccatgctgga atagatttta tgtttcgtca cctcttgtat gatttgctgt ttagtttcag
    29281 attcaattga ttctaaaaaa taacctgaac gtttatttga ctggataatg attttcttct
    29341 cgtagatagc aagcatattt ttgatttcag tttggatcgt tttcttgttg gtacctaaag
    29401 cttcagctaa ttcttcgctt gttatccaat gattcttatt tcttaatact acaagaattt
    29461 ggagttgtcg tttatttaag tccatttgct tacacctcct ctttgttata aacatacagg
    29521 aaaaacctct caaatgacaa tagtcacttg cagaggttta aaaatcattt gaagaaagat
    29581 ctatattcaa ggtttttacc attagactgg ataatttgtt tataatattc aaaactatct
    29641 tttttcaatc tcctaaagct tccgctccca tcattttgtc tatccacata aataaagcca
    29701 tatcgcttcc tcatttcccc tgttcctgcc gatacgatat cgattggtcc ccaccataag
    29761 taaccaatga tttggcaacc atcttttatt gcctcagcaa tttcctgaag atgtattttt
    29821 agatactcac aacgttttgg atcgtggatt cgattcaatt catctggtgc ttcatctagt
    29881 ccaatgccat tttcaactat gaataatggt aattcataac ggtctgtcaa ttcattcatg
    29941 acataacgaa accctagagg atcaattggc caactccaag gttcgggaga tttttccttc
    30001 aaaaagggat tatcgaaacc atttgctccg ccagtatcta cgcgcatttc tgcttctttt
    30061 ttatagacag cgctacgata ataactaaat gcaatataat ctgccgtgtt agcttgcaag
    30121 cactgttcgt ctccatctaa cattactggt gcacagtctt cttccttcca tgtcctgtaa
    30181 atataagctg gataatgccc tcggcacatg acatcggaga aaaaccatga attgcgttta
    30241 aattgcagtg aaccaaatac attctctgga tcacagtcat atgcataagt cgctaatgca
    30301 gaaaagctac acataatacc catcttagca tttggatcga ttttctttaa taattgagta
    30361 gcacgggcgt tcgctagaaa catatgatga caggcttgat aaatcacttt ttttgttagt
    30421 gtagcaatgg gttcaagttt atctctagca gggaatgtaa ccaatccagc agctgcataa
    30481 ggcatacgaa aagcattatt gatctcatta aaggtcatcc aatatttcac tttcccttgg
    30541 tagcgttcaa agacggtctg cgcataaaat tcaaaaaagt cgattaattt tcgattttgc
    30601 caccccccat actctcctac caatgctaag ggggtttcat aatgactaag agtaattact
    30661 ggctcgatat catatcgatt taatgtattg attagtctgt cataaaatac gagaccagcc
    30721 tcatttggct tctgttcgtc tcctcttgga aatattcgtg cccatgagat gcttgttcga
    30781 aaagctttta aacctaactc cttcagtaaa cgaatatcct cttcaaatcg atgataaaaa
    30841 tcaatcgctt catgagaaag ataatggagt gattcgtcta aagcaatctc ccaaatcttt
    30901 ttttcttcat tccactgaat actaggatgc tggttcatga tcccgataag cgtatctgtc
    30961 acattaggta atttgccgtc ttccaaccat gcaccttcac attgattagc agctactgct
    31021 ccgccccata aaaaattttc tggaaatatt tcctgatcca taactatctc tcctcgctat
    31081 caacaatttc ttacttgaag tatagctcga ttcatcaaaa caagatattc taactatttc
    31141 ggcagaagag aagaaaaaaa ttgaatgcta ctcttcattt ttaatattta tatataacaa
    31201 atacataaga cgatccccga aagaaaacac tcgttaacca tctaagcaaa cgatttattt
    31261 tacttccaac acaaatgctt cataaggtcg taaatcaact ttgccgtctg gtaactgttt
    31321 cagaggataa tttgacacaa taacccttaa agcttcacgt ggaatagtga acgtctgctt
    31381 ttcactggac atattacaaa taacgagcca ttgctggtct tcatatatgc gagaataggc
    31441 aaagacatgc tcaggcgtct tttccactaa ttcatagtct ccccagacga tgatgtcatg
    31501 ttttctacgc aaatcgatca atttcttgta catataaaaa acagaatctt gatctgctaa
    31561 cgcttcttct gcattgattt ctttataatt tggattgact cgaagccatg gaattccagt
    31621 agtaaaccca gcatgttcac gggcgttcca ttgcataggc gtcctagcat tgtctcttcc
    31681 tttcgccttg attgattcca agatttcctc ttttgtaaat ccagaagaaa tcctttcgtt
    31741 atacatattg attgtctcaa tatcttttgc ttccgcgata tcatcgattg ggcaattcgt
    31801 catgcctaac tcttctcctt gatagatata aggggtgcct ttcatcatat ggagcaagat
    31861 agcaaacatc ttggcacttt cttttcgata cacatcgtca tttccccaac gagaaacaat
    31921 tcgcggaaga tcgtgattat tccaaaataa actattccat ccttcatcac ctaaagatgt
    31981 ttgccatttg gataatactt ttttcagttc agagatactc aagggtttca aatcccattt
    32041 gtctttgcct tcttgctgat ctaatcctat gtgttcgaat tggaagacca tggataattc
    32101 atttctttta ggattggaat aaagtttagc gatttcggta gttgctcccc atgtttcgcc
    32161 aacagtcatc agatttttgt caccaaaagt tgcttgattc atttcctgaa gatactcatg
    32221 cagtttaggt ccattacttg tgatttcttt atccggttct ttgccaatca tatcgatcac
    32281 gtccatacga aagcccccaa tacctttatc gatccagaaa ttcatcattt gataaatctc
    32341 ttggcgaacc tgtttatttt tccaattcaa atcaggttga cgcttgctat acaagtgcag
    32401 aaaatattgc cccgtttttt catccaactg ccaagcagaa ccactgaata ttgagcgcaa
    32461 tctattaggc tcttttccat tgaccggatc acgccaaata taatagtccc gataaggatt
    32521 ttctttattt ttacgggcct caatgaacca cggatgttca tcagaagtat gattcaccac
    32581 cagatccatg atgatacgga tatttctttt ctttgcttct tcaatcagtt cttccatttc
    32641 ttccatcgta ccgaattctg ccatgattgc ttgataatta ctgatatcat acccattgtc
    32701 atcattcgga gactcgtata ctggagaaag ccaaattgca tcaataccta aatacgccag
    32761 ataatccaac ctggaaataa tcccccgcaa atctccaata ccatcttgat ttgaatcttg
    32821 aaaacttctt ggatagattt gataaacaac tgaatggtgc caccattttt gttccatgat
    32881 tttcctccta taaatggatg tttctatttt ttgcttaatc atttatttta gtctctctca
    32941 ctaaaaattg taacgctttc aaatagctat tgcaccttgt tatcggtaac agaataaaac
    33001 aaaaaaacag ctgaggaaat tccctcaact gttttttgaa aggattgatt tatgcaggga
    33061 agaatgctga tttcacaact tctttataaa cggtgttcac tcagctgtcc cttggtatta
    33121 gctcaaaaaa cggcaaaata taagaaacta ttttttcgtt tttttctcta atactcaggc
    33181 cagaacgctg atttcacaac ctctttattt cacattcaat atccacatga atcccacaaa
    33241 tacaaagaac agaccataca tgattggaga tacttctttt cctcttttag ctgctaacat
    33301 ggtaattgga tagaagataa aacctaatgc aatcccatct gaaatactat aagtcaaagg
    33361 catgccgatc aagatcaaga atgaagggat cgcaatctct aagtttcccc attcgatttg
    33421 tcgcaaagat tgtgccatca atactcctac cataatcaat gctggtgcag ttacttgtga
    33481 agtaacaact gatagtaatg gagaaaagaa caagcctaac aagaagaaaa tccctgtagt
    33541 aatagctgtg atacctgaac gtcctccaac ggcgatacca gctgatgatt ctacaaatgc
    33601 accaacagga gaagtaccaa ataaggaacc cgcaagcata gctgttgaat cagaagctaa
    33661 agctttccct acacgaggca tcttgttgtc tttcatgaaa cctgcttggt ttgctaatcc
    33721 aactaaagtt cctgctgtat caaagaaagt cacaagcaag aatgtcagca ctacgaccca
    33781 catttgaaga gaattgatgt cccctacatg ttttaatgca actaaaaatg ttggtttcaa
    33841 acttggtgct gcggcaacaa tttcagaagg cattggaatc aaacctgtga ccagacctaa
    33901 aatcgttgta gctgccatcc cgatgaagat gccacctggt acacgccgaa caagcaagat
    33961 agcagttacg actaatccaa aaatcgtcaa ccaagtagaa ccaacgttga gtgatcctaa
    34021 tcctactaat gtagattcat tcgaaacgat gatcccacct tcgctcagac caaggaaagc
    34081 gataaataga ccgataccgc cagaaatcgc atatttcaaa tctgctggga tcgcatcaat
    34141 gatcatttcc cgcagcttga agattgtgat caaaataaaa atcaaagaag caacgaatac
    34201 gccggctaat gctgtttccc atggaatccc cattcctaaa caaacagaat aagcaaaaaa
    34261 agcattgatc ccaagagcag gtgccgttcc aattggataa cgggctaata cccccattaa
    34321 aacacagccg atcgcactgg ctaatgcagt cgcagtaaac actgctcctt catccattcc
    34381 agaagcacct aatacagttg gatttacaaa taagatataa gccattgaga taaatgttgt
    34441 aaatcctgcc agtacctcac gttttaccgt ggtgttcaat ttttctattt cgaagtagga
    34501 aagtattttt tccttcatct tccatccccc taaatccgaa cattataaat aaagtccgtt
    34561 aaaatttcga tttattaata aaacaacgtg ttttatcata tactaaaaca aaacataagt
    34621 aaacaaaaaa ttcggatttt aagcaaaatc cgaacgttcc atctgattaa atccctttat
    34681 ctcaaagttc atgaacattc actttggatt acaagaattt ctttattgtg ttaataaagt
    34741 ttcttcattc tagtctcaaa aatcaatagt gtgatttgat tttaccattt cgtttctgtt
    34801 cttctttgat gaattctttt gtatcgacag gattcagatt atttagtccg ccaaaacctg
    34861 tatcgaccat ttttccccag ccttttgtct tcttttttcc tgatttgaga ttctttgctc
    34921 gaagcttctc actatgtttt gctcgccgat acttcaaata accttctaat cttcccatta
    34981 gatccactgt ttttcctcct ttttattcaa tcagacgact cagcttttcc tataacaaaa
    35041 taattgcctt cagggtcaga aaaattgaaa gtcaagatgc cattgttatc tgtgatttct
    35101 cctggttctt ccatgttctc gtagatagtt tcaaattcat ccgtaaaaaa tactaaagaa
    35161 ggcggtggtc ctaatacctc tggtgaaaac ttctgcacaa atacttttgg gaatacgcct
    35221 aattctaatt cttttgagat gctgagtaca atactcttaa attcttctgg caattcgatt
    35281 gtttcagaaa tttctgcacc aattttttct acaaagaatc ggcaaatcat ctctacgtca
    35341 ttgacataaa gcatcacacg tgttttttgt atcatcattt gacccttctt tctatttgat
    35401 tttctttcct gtctataaac tgattccatt atatcacgaa agcgcaaaca ccttgtgttt
    35461 gatactattc aagaaaaata aagcaatagt ttctaggatt gctttcctcc acaaactttt
    35521 tttacaaaaa aaaaacggca atgaatgccg ctcttcttat ttcgattctt ttataattct
    35581 gcttctgatt catctttggt tagtgtgtgt ctaacactag ttacgccaaa tgtttgatcg
    35641 attttttcct tcaacgcttc gattgcctgt gcgccacgtg ccgcttgttc agcattgatg
    35701 gattcaatga ccagcaccgc tgcttgtgtt tcttccgtca gcatcgttct ttgggcttca
    35761 cgccagttga gacagcgaca gatcgctcct tgttcatcat agtagatgat ttcttccgga
    35821 agtgccggag catcggaatc tgcacctaaa ggcaggaatg attcgccacc ttgggctttt
    35881 cctaaatgca gatttcctgc gatcttttcg atatcttctc cgccgcaagg tacgccaaaa
    35941 gacaaggaaa tactattata gatatctaca agcggattga ttgggaaaaa ttcccgttct
    36001 tgatttgcac gtttcagtaa agcttcaata gaagaacgtg cacctttttt agtcttgaat
    36061 gtggtaaatg cctgacgcca ctgagcaatg acttcgtttt ggctgaatgt ttcttctgta
    36121 aggtaatttc ttgcttcttt tgctgcctca ttcaataatt gatgatacgt ttcttcactt
    36181 tcttttgtta cgtggttatc gataccattt acggataaga tttcgatggt tgcttcagga
    36241 aatacttccc agaaattggt atccactatt acttttttca tctgttcaca cctcttgatt
    36301 agaataattg cttgatgaat agatagtctg tttggggatc atctcccata taaaaaacat
    36361 gttcgctgta tttgataaat ccttttttac gataaaaagc gagcgcaaca tcgttgtgtt
    36421 cccaaacacc gagccaaatg gctgtttttt gcttttcttt tgctttttca atagctgtat
    36481 ctagtaaaaa tgtaccgata ccttgatgtt taaatttttt tcgtacatag attcgctcga
    36541 tttctaaaaa atgatcagcc atttcctcag attgactcgt tcctgtattt agtttcaggt
    36601 aacccgcagg ctcttgatcg atactcacta ggaaaaaatc ggtttcttta tcttttagct
    36661 cttctgtaag tttttctagt gcataagctt gtgtcaagta atcagctaaa tgctccggtg
    36721 aattatcttt tccaaatgta tctgtaaatg tttcgatact aatttgttgt agtaagtcta
    36781 catctgaagg cgtcattttt cgaatttcgt atttattcac ggcttcttcc tttcaataga
    36841 tccttttatt gccttttttg acaaaattcc aatcttcgct aacattcttg catactttat
    36901 ttaaaagata ttccaattgt tttgcttctt cgtcagaaag accatttaat gcgactgcat
    36961 tggagtagtt gttttctcga atgatgaaag gatagatttc tgctcctttt ttagtcggat
    37021 agagtttctt gattttttta ttttctttat cttccaaacg ttcgatcatc ccattggatt
    37081 ctaatttctt gattgctcgg gcagtcgttg tacgatctac tttgatcatt tctgctagtt
    37141 tttcttggat gattccagga ttttcgcaaa tacgtactaa ataaagatac tgtcctcttg
    37201 ttaaatcgac ttctttgaat tcgatattgc taatagaatc tagcgctcgg gcaatcattc
    37261 cgatgtctcg aaggatttca gccatttcat cccaccttta ttttgtttgt aagactagtt
    37321 cacctctttt tgttgcaaat gcaactattt tcaataaaaa aatcaagttc ttttttaata
    37381 actagtaaag tatattcttt tcttctttta cgaaaaagct caatcacaat agatctggtt
    37441 tttgttttct aaaataagta actgtttctt cgttgttcgc ttttctgata gctttggcaa
    37501 ctcttctata ctaaaaaatc ccatgttgga agtttcatta ttctcaataa acttggcctc
    37561 ttcaccgtgg atcgcacaag caaaaacaag tttataatac tgaaaaagct gtggaatatc
    37621 tttttgttta ttcgtatcaa aaactgctcg caactgagta gtttctactg ttaatcctgt
    37681 ttcttcatag acttctttac gcacattttc ttcaggagac aatcctattt cagcaaatcc
    37741 accaggaagt gaccattctt tcgtccgttt atcttcgatt agtaggacct tgccatcttt
    37801 tttgatatag gcacgaacat ctacttttgg tgttggatgt ccttctccaa tcgttgtgag
    37861 cgcttttatt tcttcgaaag tttcttttcc tatttcactg atcagttcca atgaaatcgt
    37921 ccggatctcc tcaaaacgct ctttatcaaa tacatctttt ccataatata gaccagcttg
    37981 agaaagtgcg agtagtcttt tgtattgagc caacttcttg ttcattctct tcccttcttt
    38041 tttagcaaat gtatgactat gtaatcaagt atagaagact ggtttaatta cggcaaataa
    38101 atataatgaa atctgcaata aataaaagaa tgttaaaaaa ctcgagaaca aaagacattc
    38161 gacttctctg gggctgtgaa taaatggcgt tcaaaagctt gcatctgcgg taataagccc
    38221 caccaaacga aaaatatgac gagctattct tgtctggctg ttcttattaa ttgaggcagg
    38281 acagcttttt cacaacctcc ccactaaacg gtgttctcct accaactcct cggtcacaag
    38341 tcacaatatt catcaaacat gagaagctgt ttttttgaaa ttgctccttg tgactcggag
    38401 ctgaacgaca ggctcacgac ctctcggtaa acagcgttca aaagccaatt tttcgatatt
    38461 aagccatttc tttgttactt attgtcattg atttcttttt ctaatttatc caatagtgga
    38521 gtgtaatcca cttgagtata gtctgttaca tcaaattcat atagtgttcc taactggaat
    38581 ttgtcatatt ttcggtcggc gatgatcttt ttgaatgctt ctttcgtaat atgattggtc
    38641 cctttcgttc gatcttccaa tacgtcacca tagtgataat gatccatgat atagctcaaa
    38701 tgacgatctg attcacgatc acgtttgtac cgacgttgcc ataacacttc aaagtctgct
    38761 gttaggcgaa tcgtgatcac ctgatatccg tatctatctg ctaattcttg gagtcgtgct
    38821 ttttgcttat cactaaaagg atactcggac acaatcactt tctttcctgc ttccatatac
    38881 aaatcaagtg ctttgtaata gaaaggataa actttcgtcc tttcttgttc cgcccgttct
    38941 tccaaattgt taaacccgat ggattctgca tagtattcct tgatttcatc gagcgtgatg
    39001 gcatacatat ctggaaatcg ttcccgtagt ttattcataa gatatgtttt tcctgtacca
    39061 ggactaccag ccagaagaat gaaatacttt ttcatctcat ttatttccta agttaattgg
    39121 actttccaag ttcataaaca gtccaatctt atgcttgaca atttctttta ctgcttcatt
    39181 tgctggaatc acattatggc gaagagactt gttgatttct gtttcactaa aggtttcttt
    39241 agctactttc gtccagttga ctaaaagctc cgttccaaca ttgaatttgc ggatcccgtt
    39301 attgatcaat tcaggataat cttcttcttt cacacctgtt cctccatgga taactagggg
    39361 gacatcaact actgcatcga tttctttcag caagggaatg tttacttctg tttttgattt
    39421 gaattgtcca tgattcgtac cgatagcaat agctaatgca tccacgcctg tagcttctac
    39481 aaatttcact gcgtcttccg gtcttgtata taccttgtca ttttcagcga catggattcc
    39541 ttcttctgta ccgccgattg ttccaagttc tccttctacg gaaacaccgt gcgcatgggc
    39601 atattctact actgcttttg tcttcaggat attttctttg aaaggcagat gggacccatc
    39661 atacatgaca gaagtatatc cgctgtcgat tgcttctttg atatcatcaa agtctcgggc
    39721 gtggtctaag tgcaagactg catcaaccat ttcttcttct gcaatagctg tcattacatt
    39781 gactaacaca tgcatgccga tatatttagc ggtatcgaca cttgtttgaa taatgatcgg
    39841 cgaacccatt tcttttgctg cgcctagcat agcaggaagc atttctaggt tatgcgtatt
    39901 aaaagctcca actgtaaaat tcaactcttc tgctgttttt gttacttctt tcaatgttgt
    39961 atacatcttt tattgccacc ttatcttttt atttgtttcc tttgatcgtt acttgttttg
    40021 caatttgtcg catctcatcc attttgccca tgtagtaatc gatcccttga tcatcaccag
    40081 cacgagcagc atctgcacgc ttctggttat agaggctcat cagtttttta tacccatctc
    40141 cgatcgtctg tttattttcc aaactctttt ctaaatattg gatggcttga tcgttcacat
    40201 acaattcaga aaatttaagt ccaacttgtt cataaagttt cgctaattta tgcttatctt
    40261 gggtagtgga aatctcttgt ttcaattgtg taatctctga ttgaatcttt tcggtcgctt
    40321 ctggcgatag ggctttttct tcttttgcca gaactttttt cggttctttt tcttttttct
    40381 taaaaaatcc aaacatcatt ttccctactt tcaattaaaa tgctttcaaa actgggctta
    40441 agatccaggc atataagagt gctgcggcta ctgtatctac atcggttgct gtagcattgt
    40501 tgaatcccat cgaattaaag atcgttacta gcaaagcggg caataatgta ataaagaaac
    40561 catgagcaat accgccaatg atcgctcctc ggcgtccgcc aactgcgttg ccaaatatcc
    40621 ctgctgtccc tccggcaaag aaattggtta gcataccagg taaaatcatc gctaagccga
    40681 acatgggcaa agtaaacatg gcaataatcg taccaatcgt tgtcgtaatg aaacctaaaa
    40741 tgacagcatt tgggctataa ggaaagaaaa ctggacaatc taaggcaggg atcgcatcag
    40801 gaactaattt catagctatc cctcgaaatg ccggcacgat ttcacctaac agtagacgta
    40861 caccagctag caatacatac acacccacta cgaattggat ggcttgtaaa aaggcaaaca
    40921 tgatatagtt ttgatctcct gataattcag aagcgaatgg ttcgcctgca aataaaacag
    40981 tgatgatata tagcgggacc atcacgacca tgacagacaa ataagtatct tgcagaaatt
    41041 cgaaatgtgt cggcaacttg atatcttcga tcgacttttt attttcgcct ttctcaccaa
    41101 aaagcttagc aacaccggct tcaaataagt acccgatcgt acaaaaatga cctaaagcaa
    41161 tatcatttga tccagtgatt ttacgaatga tcggttgcgc tactgccggc atagcaatgg
    41221 cgaaacaagc tccgataaaa ccaccgacca agatcaatac gatccctcgc agaccggcaa
    41281 aatagccaaa gactgtcgtc atcgttgcca tccataaaat tgcttgacca gttaaaaaaa
    41341 tgtacttcca ttttgtgaaa cgagccaaaa taatattgaa tacaaaaatg gctaagaacg
    41401 tcagtgcaat atctctacct aaacccaaat cattcattgc ttgaccattg atagattcaa
    41461 tagaagggat gatcccttgc atatgaaatc cttcagtaaa gattttcccg aaataagtta
    41521 aacttccaac gatgatgctc gaaccggcac tcaacacttg aaatcctagg agtgtcttta
    41581 acgtgccaga gatgacttgt cctgctgatt tcttctgcag tagtagaccc aacatagcaa
    41641 tcaatgcaat ggtgatcgat gcctgagtca aaatattttc gatgataaaa ttgataacgc
    41701 ccat
//
LOCUS       DADVXV010000015        41008 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.015, whole genome shotgun sequence.
ACCESSION   DADVXV010000015 DADVXV010000000
VERSION     DADVXV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.015"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..615
                     /locus_tag="KB969_000758"
     CDS             <1..615
                     /locus_tag="KB969_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6868769.1"
                     /translation="TGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKKDYVVFE
                     EEFGHLEGDTIVGIHHKSAVITLVERLSKAIIVLKPEGRKAVDIENSINEWLQSVPKN
                     LFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMD
                     FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
     gene            complement(793..2790)
                     /gene="tkt"
                     /locus_tag="KB969_000759"
     CDS             complement(793..2790)
                     /gene="tkt"
                     /locus_tag="KB969_000759"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBB6868770.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2892..3143)
                     /locus_tag="KB969_000760"
     CDS             complement(2892..3143)
                     /locus_tag="KB969_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBB6868771.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            3290..3913
                     /gene="lexA"
                     /locus_tag="KB969_000761"
     CDS             3290..3913
                     /gene="lexA"
                     /locus_tag="KB969_000761"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBB6868772.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            4093..4311
                     /locus_tag="KB969_000762"
     CDS             4093..4311
                     /locus_tag="KB969_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868773.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4600..5112)
                     /locus_tag="KB969_000763"
     CDS             complement(4600..5112)
                     /locus_tag="KB969_000763"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBB6868774.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(5126..7423)
                     /gene="recJ"
                     /locus_tag="KB969_000764"
     CDS             complement(5126..7423)
                     /gene="recJ"
                     /locus_tag="KB969_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBB6868775.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7565..8008)
                     /locus_tag="KB969_000765"
     CDS             complement(7565..8008)
                     /locus_tag="KB969_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBB6868776.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(8009..8797)
                     /locus_tag="KB969_000766"
     CDS             complement(8009..8797)
                     /locus_tag="KB969_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6868777.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8794..9735)
                     /locus_tag="KB969_000767"
     CDS             complement(8794..9735)
                     /locus_tag="KB969_000767"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBB6868778.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9912..10499)
                     /locus_tag="KB969_000768"
     CDS             complement(9912..10499)
                     /locus_tag="KB969_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBB6868779.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10720..12027)
                     /gene="obgE"
                     /locus_tag="KB969_000769"
     CDS             complement(10720..12027)
                     /gene="obgE"
                     /locus_tag="KB969_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBB6868780.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            12321..13331
                     /gene="gap"
                     /locus_tag="KB969_000770"
     CDS             12321..13331
                     /gene="gap"
                     /locus_tag="KB969_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBB6868781.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(13416..14351)
                     /locus_tag="KB969_000771"
     CDS             complement(13416..14351)
                     /locus_tag="KB969_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6868782.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            14537..15496
                     /locus_tag="KB969_000772"
     CDS             14537..15496
                     /locus_tag="KB969_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBB6868783.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(15582..16676)
                     /locus_tag="KB969_000773"
     CDS             complement(15582..16676)
                     /locus_tag="KB969_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6868784.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16865..17626
                     /locus_tag="KB969_000774"
     CDS             16865..17626
                     /locus_tag="KB969_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6868785.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17741..18181)
                     /gene="fabZ"
                     /locus_tag="KB969_000775"
     CDS             complement(17741..18181)
                     /gene="fabZ"
                     /locus_tag="KB969_000775"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6868786.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            18401..19156
                     /gene="fabI"
                     /locus_tag="KB969_000776"
     CDS             18401..19156
                     /gene="fabI"
                     /locus_tag="KB969_000776"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBB6868787.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(19266..20279)
                     /locus_tag="KB969_000777"
     CDS             complement(19266..20279)
                     /locus_tag="KB969_000777"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBB6868788.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            20444..21364
                     /locus_tag="KB969_000778"
     CDS             20444..21364
                     /locus_tag="KB969_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBB6868789.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(21644..22144)
                     /locus_tag="KB969_000779"
     CDS             complement(21644..22144)
                     /locus_tag="KB969_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6868790.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(22251..22769)
                     /locus_tag="KB969_000780"
     CDS             complement(22251..22769)
                     /locus_tag="KB969_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6868791.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(22770..24125)
                     /gene="rph"
                     /locus_tag="KB969_000781"
     CDS             complement(22770..24125)
                     /gene="rph"
                     /locus_tag="KB969_000781"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBB6868792.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(24128..24949)
                     /gene="racE"
                     /locus_tag="KB969_000782"
     CDS             complement(24128..24949)
                     /gene="racE"
                     /locus_tag="KB969_000782"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBB6868793.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            complement(25111..25767)
                     /locus_tag="KB969_000783"
     CDS             complement(25111..25767)
                     /locus_tag="KB969_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6868794.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            complement(25783..26430)
                     /locus_tag="KB969_000784"
     CDS             complement(25783..26430)
                     /locus_tag="KB969_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6868795.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            complement(26443..27258)
                     /locus_tag="KB969_000785"
     CDS             complement(26443..27258)
                     /locus_tag="KB969_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6868796.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            complement(27272..28009)
                     /locus_tag="KB969_000786"
     CDS             complement(27272..28009)
                     /locus_tag="KB969_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6868797.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            28263..29273
                     /gene="trpS"
                     /locus_tag="KB969_000787"
     CDS             28263..29273
                     /gene="trpS"
                     /locus_tag="KB969_000787"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBB6868798.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            complement(29443..31863)
                     /locus_tag="KB969_000788"
     CDS             complement(29443..31863)
                     /locus_tag="KB969_000788"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBB6868799.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(31868..32911)
                     /gene="pheS"
                     /locus_tag="KB969_000789"
     CDS             complement(31868..32911)
                     /gene="pheS"
                     /locus_tag="KB969_000789"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBB6868800.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            complement(33220..33561)
                     /locus_tag="KB969_000790"
     CDS             complement(33220..33561)
                     /locus_tag="KB969_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6868801.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            complement(33630..37352)
                     /gene="addA"
                     /locus_tag="KB969_000791"
     CDS             complement(33630..37352)
                     /gene="addA"
                     /locus_tag="KB969_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBB6868802.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            complement(37349..40876)
                     /locus_tag="KB969_000792"
     CDS             complement(37349..40876)
                     /locus_tag="KB969_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBB6868803.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
BASE COUNT        11673 a         8785 c         7160 g        13390 t
ORIGIN      
        1 acgggagaat tcaatgtttt acatttaccg atgcaaggaa aacgaaaacc aaatggttat
       61 aaggaaaaac gtggaaaaca ggcattcaaa agaaatattt ctgagcgtaa aaaagattat
      121 gtcgttttcg aagaagaatt tggacattta gagggtgata cgattgtcgg catccaccat
      181 aaaagtgccg tcatcacact cgttgagcga ctttcaaaag ccattatcgt cttgaaacca
      241 gaaggccgta aggcagttga tattgaaaat tcgattaatg aatggcttca atccgtaccc
      301 aaaaatcttt tcaaatcaat tacctttgat tgtggaaaag aattctctaa ttggaaaagt
      361 attagtaata cgaatgatat tgatatttat ttcgcagacc caggaacgcc ttcccaacgg
      421 ggattaaatg aacattcaaa cggactcctc cgaaaagatg gactaccaaa agaaatggac
      481 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
      541 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      601 ttttgtctcg cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat
      661 tctttgtttt gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc
      721 ttctaacaca taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac
      781 aattgcttgg atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc
      841 aaattcttct aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt
      901 tgcgccctct gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac
      961 acgtttcttc actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa
     1021 gaggtcaaag cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt
     1081 ttgagctttc acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt
     1141 ttctccttgt gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc
     1201 ttttgtagaa ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc
     1261 tgttgtctcc atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat
     1321 cacttgaaca ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg
     1381 tccgtcttct ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg
     1441 gattgctgct aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc
     1501 gtagatacga gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc
     1561 gcggacaccg aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc
     1621 agccaccatt gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat
     1681 agctttcgat aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc
     1741 aacttcataa gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc
     1801 ttcaaattgt tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca
     1861 tgcatcttca gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc
     1921 ttctggaaca gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc
     1981 atcttcacca agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc
     2041 gatgactgtt tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat
     2101 cgctttagag attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata
     2161 tgcttcatag cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga
     2221 aatatcgttt gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga
     2281 acttgcttct tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata
     2341 gtgatccatc acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat
     2401 tgccataccg acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc
     2461 atctgtatga tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt
     2521 caaatcatcg attgtcactt gatagccagc taaatgaagc aagctataca acattgctga
     2581 cccatgtcct gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg
     2641 atttactttc aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa
     2701 tccaggatgt cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt
     2761 aacgccaagt tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt
     2821 ttacctttat ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc
     2881 agtatttttt actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct
     2941 tttaattttt ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata
     3001 tgatgacgca taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct
     3061 tgttcttcgg cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc
     3121 tctatttttt caggtgacag catgctcagc cctcctttta ctctccttca tattatataa
     3181 aaactgaaaa aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc
     3241 gctttttata tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca
     3301 aactgaatca agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg
     3361 atacccgccg actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt
     3421 tcacggtcat cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc
     3481 tcgtgcaatc gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat
     3541 tccagtactt ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga
     3601 cttctttcca atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat
     3661 tcgtggagat agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa
     3721 gcaagaaact gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac
     3781 ttgcaaacga ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct
     3841 cgaaccaatc atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag
     3901 tcatatctat taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg
     3961 gtctcaaact cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt
     4021 tacaaaccga acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag
     4081 aggtgagaat tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta
     4141 ggtattatta ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt
     4201 actttgtggt tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt
     4261 catgaagatc atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg
     4321 actgctaatt attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt
     4381 cacatccttt ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat
     4441 tgcggaaaaa gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa
     4501 atagcgaccc tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct
     4561 tctttaagaa taacatcaag aatagcttct tttttctgct taatattcca ttaatgtaat
     4621 gatgtcatat cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc
     4681 gcagcctacg actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc
     4741 tccagtagct agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt
     4801 atgcaatgtc aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg
     4861 aggtaacttc ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg
     4921 acatcctacg atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt
     4981 tgcataattt acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg
     5041 ggaaatatct cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc
     5101 ttttaaatcc actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat
     5161 cgctcaaaag caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc
     5221 tctcagtcaa aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg
     5281 taacaaattt caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac
     5341 gcaaatattg agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga
     5401 tcaatttaaa caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat
     5461 caggtgaaat ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca
     5521 gatccgctaa atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa
     5581 ttattgcctt tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag
     5641 gcacgaattt caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc
     5701 tctgttcacg gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat
     5761 cagataccat cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta
     5821 ccacatctac ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg
     5881 catcaagctg actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga
     5941 ttcttttgat attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg
     6001 taccaaatgg cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca
     6061 gcaatacttc atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta
     6121 tatattggtt catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga
     6181 ctgctgcatg atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa
     6241 aaagattcaa ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag
     6301 taaggacaag cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa
     6361 cgccttcatg ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg
     6421 ctaatgcttc ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca
     6481 atttttttgc ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag
     6541 gacgtggatc gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg
     6601 ttgtttcgtc tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta
     6661 tccgttctga atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag
     6721 tcaatgaaac taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg
     6781 gttcttccaa taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa
     6841 atggatagtg ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct
     6901 caggtagttc gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta
     6961 ccgcatcatt tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga
     7021 tcttttcttg gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga
     7081 atacttctac ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga
     7141 tcccatctgc gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt
     7201 ggattcggct gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt
     7261 cctttggatg taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta
     7321 acttaccgac aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag
     7381 gctctgtctc gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt
     7441 agttattata gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca
     7501 gatccgctag acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc
     7561 cctattagtc aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg
     7621 ctttcaattg actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca
     7681 actccgcacg ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct
     7741 tttgaagttc tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt
     7801 gctgccatag tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac
     7861 cgatgatcac taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat
     7921 ttttattgtt caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca
     7981 cattgctttg ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat
     8041 aatcaccaat cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt
     8101 gattgatttc ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag
     8161 gttctaaaac gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga
     8221 agaaatttgt ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca
     8281 attctaatcg caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg
     8341 ttgattttgc agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc
     8401 ttctttctgc catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga
     8461 cttcaaacat atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa
     8521 aacccgcatt gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata
     8581 attcgtccac gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc
     8641 tcaagcgtct gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta
     8701 taacgattgc tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac
     8761 tacctgttac taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg
     8821 aatctcaatg ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc
     8881 tttttcaagc tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag
     8941 ccgttttgcc tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata
     9001 gttgtgcgcc attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct
     9061 attttccgca agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat
     9121 tcgtcctttt ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag
     9181 ttggatcgtt tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc
     9241 ttttagacga tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa
     9301 actgtcgatc ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat
     9361 cggggctgtt tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat
     9421 acctaaagag acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt
     9481 atccccacct tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc
     9541 gtgtaaatgt gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat
     9601 ctgcatttgc gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag
     9661 tttcaatgct atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa
     9721 aaattgtaat tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa
     9781 aagaagggat aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag
     9841 cgatagcgtt ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct
     9901 gctgtttttt attaatttga agatccagaa ctttcattgt cgttggaagt ttgcggatgt
     9961 ttgtccttcc aagtcttttg tgcagcttct ttcgcatgat tttcagcttc tttcgcatca
    10021 tgcacatctt tttcgacatc ttcataatcc aagcgagtaa tttctccgcc taattccatc
    10081 attaccaatt gattcagtgg gcgattgtcc tcttcatcag caatcaagat cagtcctgta
    10141 gctccttcac cgattttatt tcctacaaag tcgaacacgg tctgggcatc ttttatttct
    10201 ttggcatctt gtgtcgcacc gatcattcct ccggcaaacc atcctaataa aatccctagc
    10261 ggaccaccta atacaccaac caacattccg attaatccac ccgtagaaga tttgttatta
    10321 ccggtaaagt cgataaaatc ttctattttg aattgatgtg tcccattagg atcatggctg
    10381 acaactgcca tctgttctcc tttaatcgaa cgaacagcat gtaacttttt gatttctgaa
    10441 aatgcctgat atgcctggct ttctacttga aaatttaaaa tgattactcg tttgctcatt
    10501 aaaaacgccc ctttcatacc ttcttgttat ttattttacc tttaattgaa aaataagaaa
    10561 agaaaagcac tctttttttc caataaaata gggctgtgac aaaagtcgta tcacagctcc
    10621 tttttccgaa taaacggcgt tcttgaagct gatcacttct gtcacaacct cccttaaatc
    10681 tgaatctata ttttttggta tttgttttta tttgcttgcc tattcgacaa attcaaattc
    10741 aaactcaccg atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa gagcttcatc
    10801 cacacccata ccacgtaatt gacgagcaaa acgcatcact gtttcatcat gatcgaaatt
    10861 cgtcatttgg aataattttt cgatcttctc accagataag atccacgttg catctgaatc
    10921 acgatcgatt tggaactcag gaccttctgg attgaatcca tagtgtacag tttcttcttc
    10981 cagttcttct tcgtacaatg ggaattctgg cgttacttct aacaaatctg ctgtagcatt
    11041 caataacgcg tccaatcctt gtcgagtcac tccagaaatt ggaaatactg ggatgtcatc
    11101 agcaaattca tcttcttttt ccttgttcag ctgttctttg aatttcacta gattttccgg
    11161 tgcatccggc atatccattt tgtttgccac gatgatttgc ggacgctcta gcaagcgtaa
    11221 gttataagta gataattctt tgttgatggc aagatagtct tcataaggat ctcgtccttc
    11281 catcccactc atatcgatca catgtaaaat tactcgtgtt ctttcgatat gacgaaggaa
    11341 ttgtgtaccc agcccaacac cttgcgaagc tccttcaatc aagcctggca agtctgctgc
    11401 ggcaaaactt ctgccatcac ttgtagtaac cattcctaga ttaggtacga gcgtcgtgaa
    11461 atgataagcg ccgatttttg gacgagcaga tgaaataacg gatagtaaag tcgatttccc
    11521 gacagatgga aaacctacaa gtccaacgtc tgccaatact ttcaattcta gttcgatttt
    11581 tcgctcttgt cctggttcac cgttttcagc aatttccggt gcaggattcc gaggagaggc
    11641 aaaacggata ttccctcgtc caccgcgtcc accttttgcc acaactagtg tttgaccatt
    11701 ttcaattaaa tctcctaaaa gagcaccagt ctccgcatct cggacagtgg ttccttgtgg
    11761 tactttaaca taggtatctt ctgaaccacg accgtgcatc cctttactca tcccattttc
    11821 acctggctgc gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac gtaacccttc
    11881 atcgacgatc aagatgacat cgccgccacg accaccgtct ccgccagccg gtccgccgtc
    11941 aggaacgtat ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc cagctttcac
    12001 atcgatcgtt acttgatcta aaaacatgga cataattaag tcctcctatt attcatttat
    12061 ttatttgact gcctgaattt ccacaataaa caaaagtctt acttatttta tcggtgaaat
    12121 ctgattttgt ctatcatttc agcaaaaaga ttgtttacct tcttcttttt ttatcatttg
    12181 gtaaggtttc caaccttttt tctgctacca agtataattt tttgacaaaa tattctttgc
    12241 gtagcagaat aacagtgtat taattgtatt aattgaggat gccgtttcac agcaccccta
    12301 ataaaggagg aacttttgat atgacagtaa aagtaggtat taacggattt gggcgtattg
    12361 gccgtctggc tttccgccgc atcaaagaag tctcagatga tattgaagta gtagcaatca
    12421 acgacttaac aagtccaact atgttagcac aattattgca atttgactct actcatggta
    12481 cttatcctgg cacagttact gcaacagaag actcaatcgt agtggatggc gaagcaactc
    12541 gtgtttatgc agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac ggtgtagata
    12601 tcgtactaga atgtactggt ttttatacat ctgaagaaaa agcaaaagcg catttagatg
    12661 ctggtgtcaa acgagtagtt atttctgccc cagctggtgc tatgaaaacc atcgtctata
    12721 acgtcaatga tgatacatta gatgaaaacg acaaaatcat ctcagcaggt tcatgtacaa
    12781 caaactgttt agcacctatg gcttatttct taaataatga atttgggatc gaagttggta
    12841 caatgacaac agttcatgcc tacacttcca cacaaatgct cttagatgga cctgtaaaag
    12901 gcggtaattt gcgtgctgct cgttcagctg ctgacaatac tatcccacat tctactggtg
    12961 ctgcgaaagc aatcggctta gttatccctg agctacaagg aaaattacaa ggacacgcac
    13021 aacgtgttcc agtcgttgat ggttcattaa ctgaattggt ttcagtattg aaaacaaaag
    13081 taactgctga tcaagtaaac gaagcaatca aaaaacacac agttgacaat ccttcattcg
    13141 ggtatgatga ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa ggttcgatct
    13201 ttgacccaac gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt aaaactgttg
    13261 catggtatga caatgagtat ggatttactt gccaaatgat tcgcttacta gaaaaattcg
    13321 ctaacttgta atttgataga tcaatcgata aaagaagcct ttgactggat ccagtcaaag
    13381 gcttctttct tttcatcccc tacttttaaa ctcgttcaat gaacatattg gcttaaaaat
    13441 tgttggacta cttgctgata tttttcagga tctgtcttgt atgcttccgc atgctcggct
    13501 ccttttacaa catacttttc ttttggtccc ttcgttgcac gatagacctt atctaacatt
    13561 tcaaatggta caaatgtatc ttcgtctcca tgtataaaga gcattgggcg ctggtttttc
    13621 ttcaattgtt ccactgcatt tgcttcaccg aaaaagtagc cagcacggac ttttgtcact
    13681 agactcgtta cttgcataag cggaaatgct ggaagactaa acatatcgtc tagctgataa
    13741 gcaagctcat catgaacgga agaataaccg caatcttcaa tgattgcttt cacattatct
    13801 ggtagttttt ctccgctagt catcataact gttgctgctc ccatgctgac accgtataga
    13861 acgatttctt gcgattttcc attgttttct agcactttgt ttatccactg tacatagtct
    13921 ttacgctctg gccatccaaa tccaatgtaa tccccttcgc tttttccatg tcctcttgca
    13981 tcaggaacaa ggacattgta acccatatca tgaaacatct ttgcgtaatt ggtcatcgtt
    14041 tcagcgtttc ccatatagcc atgagccaca agagctgttt tttcactttt cgtttcagca
    14101 ggaagataaa tcgctgataa tttcagaccg tcttttgaag tgatggtcca atcgcttcgg
    14161 ttttcttttg aactaaacca tttatgtgca tccgtttctt tggatgtctg tgttgtacca
    14221 ggtgtatctt cgtctaaaaa gtctttctca gaaggcacaa cagcataatt ataaaaataa
    14281 ttccctgcaa acactaacgc aacaatcaga gctaaagcga cgcctaaaag gattttcatc
    14341 caaagtttca taaatcatcc atctcatttc tcttttttca tataaccttg aattagtata
    14401 atcaaagaat ctctactatg caatgttcat ttttataacc cgcgaattgt aaaattaagt
    14461 tagaaaaata aaaaggcatt tatggtacac tcaaattgta tttccgacga aagaaaacaa
    14521 aggagtgtaa ccataaatga cctacaaaca tcttaccata gacgaactga caatgataga
    14581 atcatattat cttcaacata ataagccggt tgaaatcgct aaccgaatgg gacgtgctat
    14641 acaaactatt tataatgtag tcaataagtt caagcaaggc aagactgctc ttgattattg
    14701 gcaccagtat aaagaaaata agaaaaaatg tggtagaaaa gtcattcaat tacctgctca
    14761 tgaagtagat tacattaaag agaaagtcac tcttggttgg acgcctgacg tcattatcgg
    14821 gcgaaaagaa aggtctgttt catgcggtat gagaacactt tatcgtttat tttctaaagg
    14881 aatatttgat attgacacac taccgatgaa aggtaaaaga aaacccaatg gccatcagga
    14941 aaaacgggga aaacaacagt atcagcgctc aatccatgat cgacctgata attatcctga
    15001 tttcaattct gagtttggtc accttgaagg tgatacgatc gttggcattc atcataaaag
    15061 tgccgtcatt actttagttg aaagattatc taaagtcatt atcacgatta aacccaacgg
    15121 ccgtaaggca ttagatattg aaactgccct taatcaatgg ttttctcgct tccctaaaaa
    15181 cttctttaaa tctattacgt ttgactgtgg aaaagaattt tctaactgga aagccattag
    15241 taaccaacat gatattgata tatattttgc ggaccctgga acaccttctc aacgcccatt
    15301 aaacgagaat tctaacggga ttctgcgtcg taatggactg ccgaaatcaa tggattttag
    15361 aaaagtgaat cagacattta tttccagtgt cagcaatcaa cgtaatcata ttccaagaaa
    15421 atcattgaat tacagaacac caatcgaaat atttttgagc tatgtacaag aagcatttta
    15481 ttctagctta atttgacaaa tcataaccta taaaaaaaca aaataaaaaa gcagaaataa
    15541 ctggctattt ctagcggatt atttctgcaa taactaatta tctatttttt attttcaatt
    15601 aatttaaagc ttgaccatgg tttcaaaaag tcaaggagga ataattcgtc atcggagatt
    15661 cttcctacaa cattgacacg tccgtcgttt ttcatatcct tcaaggcgat ttgtgtttct
    15721 cctttgtatt gaccgtaccc ttcattgtca atcagtacat ccccatgatg catatctcgc
    15781 gtattatgag gcgggaaatc tttatctttg tagtatacac gagtcatcgt tgaacgaagg
    15841 atatattctg agcgatcccc tcgataacta tgaaggttat caaacaagca gattcgttcg
    15901 ttttctgtaa taccttcttc cgtatctact ttcaatgttg gataatccgc gttaaatgct
    15961 tctgccattt ctttcaattc ttcttcactt gcgtacgcat ttccaataga aatatcatca
    16021 atcaatcctg taaggattaa atgcttcact tgtgtcgcaa tttcaagatc tcggtggtct
    16081 tccagcgtgc acaagccatc ttgcgtaggc caagggccaa actcagcaga ttgcgaattg
    16141 acgaatgcca tcgtattcaa attatatttt ctgaattttt ctgaacaaaa aacaaagtgt
    16201 tcgtatccta aaccagagta tcgatgagga taaaaattat gagaacctaa taaattatcc
    16261 gtgtttggcg aataactcat gatgttgtca acgtaattcg tgcccgaact catattgatc
    16321 tcgattttga taccaaaagg attgcgcgtc atttttgctt cttctgctcc tgtgaatccg
    16381 atatctaagc ggaccccgta ggcacccatc ttatggaaaa aagataagtc atcgtaagaa
    16441 atctccaact gttcaaataa cgctggattg atatcaacca ttacttccat gcctaggcta
    16501 ttcgcgtaat caactacttc tttaaattct gaaagaactt tttctttatc atcattgatc
    16561 tgcagcaaac tggtaaaaac ccgtttatac ccatacttat gagctaaatc caagtacgct
    16621 ttgtcctttt caaatgttga ccgttctgga taaatcgaga ttcctaattt tcccatatta
    16681 ccatttcctc ctgcatcttt tcgtttttgt atccacttac attatagcaa acacaaagta
    16741 aatggtctac accttttctt tttcttttaa aataaatgat aaattccaat aatttaagta
    16801 ggtattttcc ctctattttg ttatcattaa agataacaaa atagtaaatt ggaaaggaac
    16861 agttatgaag aaaaataaag ttattttaag tattagttta gcagcagcat tgctgtttgc
    16921 tgctggttgt tctgcaaaca acacgacttc ttctagttcg tctacagaaa gttcaaaaag
    16981 tacatctact gcggaaagca cgactgccag tagcgtcgat ttgaacgcat tggaattacc
    17041 acaattgacg aaagatgtcg ccgaaaatga agatctggtc gaaatggtga cgaataaagg
    17101 cacaatcaaa atcaaattat ttcccgaaca cgcaccaaaa gcggttgaaa actttatgac
    17161 acatgcaaaa gacggttact acaacggact gactttccat cgcgtcatca aagatttcat
    17221 gatccaaggt ggcgatccta aaggcgatgg cactggaggg gaaagcattt ggggagaagg
    17281 atttgaaaca gagatcaaca accaccttta taatataaga ggtgcgttat ctatggctcg
    17341 ctcacaagat cctaacagta acggcagcca gttctttatc gttcaaaata cagatgatat
    17401 gcatgatggt cttttaaaag acgactatcc tcaagcaatc atcgacgctt ataaaaacgg
    17461 cggttatcct tcactagatg gccattatac tgtcttcggc caagtgattg aaggaatgga
    17521 tgtcgtggat gctattgcaa atatcgaaac agatagttca gacaaaccaa aagaagaagt
    17581 aaaaatcgat aaaatcaata tactgcaaga agcaaaacaa aaataaaaaa ataacgtctg
    17641 aatcctgcat agatgacaac gtatgctagg attcaggcgt cttcttttta cataaaaagc
    17701 aagtaagctt ccttttgttt tgctatatca ggttttatag tcaagcattt tggttgacga
    17761 tgaacgtgaa ctcgcactca cagacttttt tatcatctac atatgctgca gataacgctg
    17821 taccgactga tcccttcatt ttggtgattt caaaatgaca tttcagcaca tctcctggaa
    17881 caactttttg acggaatttg gccttattga tcccaccgat ataagctctt tttcctagaa
    17941 actcttctga ttttaggata agtatcgaac ctgcttgtgc cagtgtttct agaatcaacg
    18001 cacccggcat cactggattg tcaggaaagt gaccttggaa aaaatcttca ttgattgtta
    18061 cattttttgt cgcaacgatc ttttttcctg gttctaaagt atctacataa tcaatataac
    18121 aaataggata acgattagga atcaattcca ttacttcagt agcagataat acgtaagaca
    18181 taattaaact ccttctttca ggcaattgcc attttcatta ctttgactat caaagtatca
    18241 tattcctaaa tatttagcaa tcttttttta atttaagaaa aaatagtttg acaatcaaaa
    18301 cattttgact aataattaag aaatcaagaa gttattttag ctattattct ctattttttt
    18361 acgactatca aatttttatc agaaacaaag gagagtcatt atgtcatttc tagaaggaaa
    18421 aaaaatcgtc attatgggcg tcgctaacaa aaaaagcatt gcttggggtt gtgctgaagc
    18481 aatgttgaaa caaggggcag aaattatcta tacttaccaa aatgaacgaa tgaaaaaatc
    18541 attagtcaaa ttggtcggcg aagaagcatt cactgtagaa tgtgatgttt ctagcgacga
    18601 aagcatcgaa aaagcaatga atgccatcgg tgaatatgct ggggagatcc acggccttgt
    18661 ccatgcagtt gcttacgcca acaaagaaga attgtccgga aatgtgtctg atatttccag
    18721 agacggctat caattagctc aagatatcag cagctactct ttaattgctg tatcaaaata
    18781 cgcacaaccg tttcttgcac caaacagcgg gatcgttagc atgacttatc taggttcaga
    18841 acgcgcaatc ccgaattata acatgatggg tattgcgaaa gcttctcttg aagctgctat
    18901 ccgttatttg gcagctgagt tctcgcctaa aggaattcgg gtcaatggaa tctcagctgg
    18961 ggcaatcaaa acattagctg tcacaggtgt taaagactat caaaaactga tccagttatc
    19021 tgaatctcgt acgcctgatc agcaaggtgt gacgatcgaa gaagtcggta atgcttgtgc
    19081 tttcttaatc agcccacttt ccagcggaat catcggtgat attatctacg ttgacaaagg
    19141 tgtccatctt tcataaactt ttgttgcatt ctttaaagta aaacatataa aaatcaggaa
    19201 aaaacttttt aaagtctctt cctgattttt tctttttacg tttttttcaa ctcattactt
    19261 tgaaattatt ccacgacttc aatccagcct tctggtgctt ctatgtctcc aaattgaata
    19321 cctgtcaatt catcatacaa ccgttttgtt actggtccta cttccgtttc actataaaat
    19381 acatgaagat tgttattgtg ataaatccca ccgattggag aaataacagc cgctgtacca
    19441 catgcaccag cttctgcaaa ttgatctaga tcatcaatga aaatatctcc ttcaattgct
    19501 tgcagtccta gtcgttcttc agctaactgc aacaaggaat atttcgtgat acttggtaag
    19561 atagagggcg attgcggagt gatgaatttt ccgtcttttg taattccaaa gaaatttgct
    19621 gcacctactt cttcgatttt cgtatgtgtg gctggatcaa gataaacaca atctgagtaa
    19681 tccagttctt ttgcttctgt tcctggaagt aaactcgctg cgtaatttcc gccgactttt
    19741 gctgcaccag tccccttagg agcagcacga tcgtaatcag atacaataaa attcgttggt
    19801 tttagtccac ctttgaaata cgctcctact ggcgtacaga agacgacaaa taaatattct
    19861 ggagctggat ggacaccaat gttttcaccg accccaatca gtaaagggcg caagtataat
    19921 gtagcgcctg ttccataggg cggcacaaaa tcttcatttg cttttaccac ttgcttgaca
    19981 gcatcaacga acatcttttc agggaccatt ggcatcagca atcgtctagc actttgattc
    20041 atccgtcgac tattttgttc aggtcgaaag agattgacct tgccgtcttt tcgacgataa
    20101 gcttttagac cttcaaaaca ttgctgacca taatgaagcg ctggagagcc ttcatgaatc
    20161 gtcaggtaat tatcttctgt caattctcct tcttcccatt gtccgtcttt ccatttggca
    20221 ataaaacgcc aaggagtttt gatataagaa aaacctagat tgttccaatc gatttgcata
    20281 tacttaccac cttcgttatt ttctccacat tttatcatta tccatattat ttgtcatttt
    20341 attttcagct tttttccttc attatagtta tttttgctat ttcctttttt gaaaacttct
    20401 tggtacaata cagaaagaat caaattttag aaaagaggat tttatgtttt cattattagc
    20461 aactgccggt acgacagact cttctggcga gacattgaca gatcaagctg tcagcaaagt
    20521 aaatgcgttt cagcggtttt gggacgggat tgattgggac gccattttgg ctgcctttat
    20581 ccaaaaaagt ttatatctga tttttttgat cgtccttttt tggattcttc accgtgtggg
    20641 aaaatatctg attgataagt cttttaatca gtattctaaa aaagccattc taaacgagag
    20701 ccgcttaaag actttacata gtcttttaaa tactattttt cattataccc ttggtttctt
    20761 ttttatctat gcaattttat ctgctatcgg tgtgccgatc ggatcacttt tggctggtgc
    20821 cggaattgca ggtgtggcaa tcggtcttgg tgcccaaggg ttcatgagtg atgttattac
    20881 cggatttttt attatcatgg aacaacagat ggatgttggg gactacatca agctagcaaa
    20941 cttaacgatt gaaggaaccg tcgtatctgt tggtatccgt acccttcagc tgaaagcaac
    21001 ggatggtact gtccatttca tcccgaatcg aaacatcacc acgatcagca atctctctcg
    21061 tgcaaatatg caagtacttt tagatattcg gattgttcct gaagaaggat atgacaaaat
    21121 ctatgagatc attgatcgag taaatcgtac attagctgaa aaataccaag aagagctcca
    21181 aactgaacct tctatctttg gattagtgga tcttggaaac agcaattttg cgattcgtac
    21241 ggtctgctac gcattgaacg gaaaacaata tgccttaaaa gaagagttct tgagctccta
    21301 tgtcaaagaa ttgacagctt ctggtttcac gattccgaac agtccaattg ctgtcggaaa
    21361 ataatttgga caaacgatgc aacgaatctc actaaaaaga gcgtgggaca aaagtaaaga
    21421 acacttttgt cccacgctct aaacacgtat aaacggcgga agcagaagca actccttcgg
    21481 aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaattcct tcttatttct
    21541 tggagttaaa cgcttttgtc ccagcctctt tttcaagata aagtcaaaac tggtacgctg
    21601 ttttttctac ttattttttg attatctttt agtttctcgt tctttagctc acgatatcga
    21661 tttgttcttt taattcttcg attttcggag acaatatatt acgacgttct aattcatgca
    21721 ccatgaagtt tacggcttta agcagctctt ttcttgtaat gattcctttg aaaatccgat
    21781 cttctgtgac aaccggtaaa aaaggcgaat cgactaacaa atggagtact tcttctagtt
    21841 cccaattttc atcaattgtc ggaacatctg tttctgtcac atcagcaacc gttagtcctt
    21901 ctaacgggtc catgctgatt gtttgcaagt caatcatttt attgaccaca tctgataaac
    21961 ttactagtcc tacaaagtga tcatcttttc ctaatacagg aattttggaa taaccgacct
    22021 tcgataacac aagtaaacca tgggacaatg gatgatgata cataacattt gccacatttt
    22081 ctgcaggaat caaaaacgtt tcctgatttt ccagcagcat ttctcttact ataggtccaa
    22141 tcatctgatg gcctccattt ctatttcatt caacactact attttaccga aaccggatgc
    22201 aaaattcata aaataaagct tatttttatt aaaaattaga gtttttttat tcagcgctct
    22261 ctcgaaaaag aaaaggccaa ctcttcaact gcctgatggg cacggttata gtattgaaca
    22321 gaaatttggt catctaaact ttcgataaga gcatatgatg ggatttggat cgggcctcta
    22381 ggctgagaaa tgctaccagg attcaaaaac aggattttct gatccatctc acagcctatt
    22441 tgatgggtat gaccaaaaaa caccatatcg gcagttgcag ctcgagcttc gattgctaac
    22501 tgtgtcaaac caaatcggac attcgataaa tgaccgtgag tcatgaatac tgtatcctga
    22561 ccagtttgga tcactttttt ctgttcgaat cctggtccat aatcacaatt accttgaacc
    22621 acttggaatg tatcccataa tgggtcagaa gcttctaatt ccgaatcacc acaatggaaa
    22681 aagatatcca cttcagaacg ataacgatct actaagtcaa cgaggatatc tctgtctcca
    22741 tgattatcac ttactactaa ataccgcatc tatctctctc cttccagcca ttgtttccac
    22801 tcggcactca attttttcat tgcttgagcc cgatgactga tcttgttttt ttcttcgctc
    22861 gataattctg ctgctgtttg tttcttacct tctgggataa ataaaggatc atacccaaag
    22921 ccattttcgc cagatggtat acgggctact cgaccgggcc attccgcttc tactacaagg
    22981 ctgtcttttt tgggtgccgc gaatactaac gtacaatgga attgtgctgt tcttttttca
    23041 tccggcacat ctgtcaattc atataataat ttggcgttat tccccgcatc acttttttgt
    23101 tcccctgcaa aacgtgcaga atagattcct ggcataccgc ctaaagcatc cactttcaaa
    23161 cctgaatcat ctgctaagac tggctgatca agcaattgtg caatcgtttc tgcttttaat
    23221 cgggcatttt cttcaaatgt gctgccagtt tcttccacat ctggcaattc aggatagtca
    23281 agtaatgttt ttacatgata tcccgcttct ttgaacatat ttcgaaactc ttctgctttt
    23341 cctggatttc ttgtcgcaat gatgattgtt tttgtttctt ctatccgctc atcattttga
    23401 gcaaactctg ttagcaaagc atgtttttgc tctttgatca aatcttcaat cgcgtttttt
    23461 ccaaaaaaga gcatttcatt caactgttca ccatcaaacg ttgcttcttc tccagttcct
    23521 tgaatctcca cgaattttcc agattctgtc attacaagat tcatgtctac aagtgctgcg
    23581 gaatcttctt ggtaatccaa atctgtgacg caagtcccat ctggtaagat tcctacgcta
    23641 actgcagcaa gatgttcttt tattggatct tctgacaatt ctttttctct taaaagtttt
    23701 tcaatggcta atttcaatgc cacaaatgcc ccagtgatac ttgctgttct agtaccgcca
    23761 tccgcttgga tcacatcgca gtctacgatg atactacgtt ctcctaattt ttccaagtct
    23821 actactgcac gcaaggaacg accaataaga cgctggattt ccattgttct accagaaagt
    23881 ttccctttgc tgctttctct acgatttctc gtactcgttg ctcgaggcag catactatat
    23941 tctgctgtca cccatcctgt tcctgtttct ctcaaaaaag ggggaacaga attttctatt
    24001 gttgcagaac aaataactgt tgtatcacca aaacggatca ctaccgatcc ttctggatat
    24061 ttgaaaacat ttgtttgaag ctccagtttg cgaagctctt gggcttttct cccgtcatga
    24121 cgcatcctta ttttcctccc aattcgatat gttctacatt taagtgtccg attccaagcc
    24181 agtcttcagc tatttcctcg aaaagtttgg cagagccagt tgtataaaac tggcataatg
    24241 tccgaccatt ttgcggtgaa ttgctcaaat tgaaataatc taacagcata gatacttcac
    24301 ctactgtttc tgctccagaa tcgatcagtt gaacattttc tcccattaca ttttgaatga
    24361 tggggcgtaa taatggataa tgggtgcatc ccaaaatcaa tgtatcgatt tttttagtgg
    24421 ttaaaggagc taatgtttct gccacaattt ttttcgccac cgatgaatgg tattcattac
    24481 tttcgacaac tgaaacaaat ttgggacaag caagacttgt cacagtcaat tctggtactt
    24541 tctctttcag tgctttttca taagcttgac tttttaccgt accaatcgta ccgataatgc
    24601 caacttgttt attttgtgtt ttttttactg ccgctctagt accgggaagg atcacaccga
    24661 tgactggaat agaaagagca gctttgattt cttctaaagc caccgcagtt gcggtattgc
    24721 aggcgatcac cagcatcttg attccttgct ccaccagata atccgtcatt tcccaagtat
    24781 actggattac ctgttccgcg ggtctagggc catatgggca gcgtgctgtg tctcctacaa
    24841 ataaaatatt ttcattcggt aattgtttca gggcttcttt tactacagtc aagccgccga
    24901 cacctgaatc aataaatccg atagggcgat tatctgtcaa tcgtatcatc ctttttttca
    24961 ataaattcta tcctccctat tgtgtacttt ttagcgtgaa ttttcaagtg ctcttacttg
    25021 cttaaaacaa tcgaaatctc tttttttcga atggaaagag gaaaagcggt tgtgacttta
    25081 gtttgccaca accgctaaaa gaatcatcta ttaataactg taccgtctct tttccaagta
    25141 accggaaagc agagaaagcg cgtaacatac cacgaagtac ataagtgtca tgatgatgaa
    25201 catcggaagc acataattgg tgttctgtcc ataaataata cgtgcctgat gagaaagttc
    25261 aggtaaagaa atgattactg ctaatgaagt atctttgatc agtgaaatca attggctcac
    25321 aattgccggg atcattgatt taaatgcttg cggtaacacg atcgttcgca tcgattctac
    25381 ataagtcagt cccgttgata atcctgcttc catctgtcct tttggaacag cattgagtcc
    25441 agctcggaaa atttccgaca acatagctga ctcaaaaatc gttaatgctg cgacagcgga
    25501 ccagaagatg ttcatctgaa tgccgatttg aggtaaggca aagtaagtga agaaaatgat
    25561 caataataat ggaagattcc gtataatatc aatcactaca ccaaggattt tggaaaagaa
    25621 agggatattc gcaaaacgaa tcacacctgt cagaccaccg atcaagaaac taaaaatgat
    25681 cgaaaacaat gaaacttcaa cagtaacctt taatccttcc aataaaaaac ggatattcat
    25741 ccatgaaaaa gcgccgctaa aatccatgta tttcccctcc ttctatgaac gaaccgccca
    25801 ttttttctca agataaacca ttaagtaaga taacggtagc gtgataacta agtaaaataa
    25861 cccaacgatg atatacgtat cgaaggtatt gaatgtttca ctagcgatca agtctccttg
    25921 atacatcaaa tctaaaccag ctacgattgc taaaatagat gagtttttta cgaggttgat
    25981 aaattggttg cctaatggcg ggataacgat tttgaatgct tgcggtaaaa caatataacg
    26041 catgatttct gaataggtaa aaccagaaga tagtcctgct tctgtttgac cttttggtac
    26101 ggtttgaatc cctgaacgta ctgtttcagc aataaaagca gatgtataga tcgttaatcc
    26161 aatcgtacct gcttggaatc catctagatt aaaccaataa atcggtacga caacataaaa
    26221 aaacatcacg atgattaata atggaatgtt tctaaaaaat tctacatatg cctttgctaa
    26281 ggcgctcact actttattct ttgataattg gaagattgcc attaacgttc cgataatcaa
    26341 actaaacaca agtgctaaga cactcgaaaa caatgtgatc ttgaacccgt cgacaaagat
    26401 tggtccataa gtttgtatca attcgctcat tgcctctccc ccttactcta cttttccttc
    26461 agtttcattt ggaaaccatt tttgatagat tttatcgtat gtgccatctg catgcatttc
    26521 ctctagcgct tggttaacag ctttcaagaa gttttcttgc cctttgttga tcgcaatccc
    26581 gtaaggctca ttagtaaacg ttccaccaac taactcatac tctggatttt catctgcaat
    26641 ccctaacaaa atcgcattat ccgtagtcat cgcgtctccc tgaccagatt gtaaagcagt
    26701 aaatgcttct gcatagtttt ctaattctaa aatttttgca tctggtgcat gctgtcggat
    26761 attcgcagcc gatgtagaac ctttgactgc tagaaccgtt gtagaagcat tcaaatcatc
    26821 tacacttttg atttggcttc ctttctttac caacaaagct tggccagcat cgaaatagac
    26881 atctgaaaag tcaacctgtt tttttcgttc atctgtgatc gtcatcgttg caataattgc
    26941 atcgatattt ccgtttttca ataatggaat ccgagtttta gaagtgactt caacaaattc
    27001 tgtttttcca ttgtcaccaa ggatcttttt agtgattgct tttgcaatat ctacatcaaa
    27061 tccttgtaca gttctgctct caatatccat cattccaaat aatcgagtat catacttgac
    27121 accccagatg atttcattgg tagatttgct tcgctctaaa atatcttcat ttgccaaccc
    27181 atttccttta catccggcta gtgcaagaaa agcaatgcct aaaaggaaaa tcaggcgtat
    27241 tttttttaac ctgcgcatct ttttcctcct atcaatgatt gataacttta ctgataaatt
    27301 gctgtgctcg gacttcattt ggattttcga aaaagtctct cacatttctg ctgtcttcca
    27361 atacttctcc atcagccatg aagataacac gatccgccac ttctttggca aagcccattt
    27421 catgtgtcac gacaatcatt gacataccgt catgagccaa ttttttcata acgtctaata
    27481 catcaccaat catttccgga tccaaagcag aagtaggttc atcaaacagc agcatctcag
    27541 gattcatcgc taaacctctg gcgattgcca cccgttgctg ttgtcccccg gataacatgg
    27601 aaggataaga atctttctta tctaacatat tgacagtttt caaaaatttc tccgcgtttt
    27661 tgactgcagt tgcctggtct tgcttcaaca ctttgattgg tgctaatttg atgttttcca
    27721 gaacagtttt atttgggtac aaattgaaat gttggaaaac catgccgatg ttttttcgga
    27781 cttctgtcag ttttgtcttt ttatcatgca agtcagtatc attaatcagc agcttacctg
    27841 aagagatcgt ctctaatcca ttgatacagc gaagcatcgt gctctttcct gaaccagaag
    27901 gaccaatgac aacgacaact tctcctttct cgaattcgag attgatattt tttaatgcgt
    27961 ggaacttgcc ataatattta tccacgtgat caaatttaat cattgccata gaattacact
    28021 cccattatta tttagtaaga tttcttttaa agatgtataa taaaatacat tatatctgat
    28081 agtttagtaa tttgtaaagt ttcttagaac gtttattctc ccataaatat ttcttccatt
    28141 tctaatctat tagttatttt atcctctttc cttgtttttt ccttaggaac tgttgtttct
    28201 tttcaggaaa aacggtaaga tattaagtgc tcagacttac aaatcgtaaa gaggtgtctt
    28261 ttttgaaaaa tattatttta acgggagatc gaccaactgg gaagctgcat ttagggcatt
    28321 acgtcggttc tctaaaaacc cgagtggcta tgcaggcaga tgaagacaac caactgtttg
    28381 tcatgattgc tgacatgcaa gcactgacag ataatgctaa aaatcctgag aaggtttcat
    28441 caaatgtctt gcaagttgct ttagactatt tagccgtggg attagatcct gcaaaatcta
    28501 ctttatttat ccaatcacaa attccggaat tagctgaatt aaccatgtat tatttgaact
    28561 tagtcagcgt aggacgcgtt cggcgcaatc cgactgtcaa aacagaaatc gaacaaaaaa
    28621 aattcggtga aagcgtgcct acaggattct ttatctatcc tgtttctcaa gcagcagata
    28681 tcactgcatt caaagcgaat cttgtacctg ttggtgagga tcaaaaacca atgctagagc
    28741 agacacagga aatcgtacaa agcttcaatc atacatatgg tgaagtcttg gtggaaccaa
    28801 aaggcgtatt cccaccaaaa ggaatgggta gattacctgg aatcgatgga aatggcaaaa
    28861 tgagtaaatc gttaggaaac ggtatttata tctccgatcc tgccgatgtc ttacagaaaa
    28921 aagtcatgag tatgtatact gatccaaacc acatccatgt acaagatcct ggacaagtag
    28981 aagggaatat ggtcttcacc tacttggatg tattcggaac agataaagaa gcaattgaag
    29041 aaatgaaagc tcattaccgc cgcggcggac ttggtgatgt aaagatcaaa cgatacctca
    29101 ttgatgtatt ggaagctgaa tttgcaccga tccgtgcgcg ccgagaagaa ttggaaaaag
    29161 atccttcagc tgttatggaa atcttacgta aaggtagtga agaagctgct aaagtagctg
    29221 cacaaacact ttctgaagta aaatcagcaa tgggaatcaa ttacttccat taattcattt
    29281 actctaaaaa agcaggctgt aaaggcctgt ttttttatct cgtctctgtg ctattccttt
    29341 tttaaaatca aaaaaagaga tgtgacgaag ttgtgtcaca tctttttttc aaatgtatgg
    29401 tcttcaaaag ctacttgatc gttacttact atattttcct tcttagcgaa tacttgcctc
    29461 taggttttct accaacgctt tttcgacttt ttccattgct ttattgattt cttcatctgt
    29521 caatgttgct tctgggttga cgaatgtcag gctatacgcc atggatttat gtcctttttc
    29581 aatgttttct ccttgataga catcaaataa ttggatatct gttaaaaatc ttccggcagc
    29641 agaacggata acttctgtta attcctgatt tgtcacagtt tcttttacaa gcaaagcgat
    29701 gtcccggctg actgctggga attttgtcac tgcttcgaaa acgatccctt tttgagcagc
    29761 ttccactata gcagataaat caaactcagc aacatatgtt tctggaatat cataactttt
    29821 tgtaatcgtt ggatgcactt gaccgacaaa accaataaat ttttcgccaa ggtaaatcgc
    29881 agcagttctt ccaggatgca tttccttcat ttctgtcact gtttgataat ggacatcttc
    29941 agtgatgcct agttgttcaa ataagttttc taaaagaccc ttgatggtga aaaagtctac
    30001 attttgagct ttcgtctgcc aatctttttc ttcccaaata ccagaaatag cgattgctgc
    30061 atgttttact tcttgcggca gatgtgtacg tggatcattt tcttggaaga acacccgacc
    30121 aatttcatat aaagcaatct ctgtattttt tcgggcagtg ttataactga tatcatctaa
    30181 tagtccgctg atcaaattca ttcgtaatac agaacgttct tcgctcattg gccagtccaa
    30241 acgtgtaata ttactttcat ttataacaaa ctgtcttgat ttttcttctg ttgtcaatgc
    30301 ataactgatt gcttcgctca atccgcttcc ttcaaagatt gtacgaattt tacgagtagt
    30361 ttcttgttct tttgacaagc ttccagcaac cgtttctcca cttggaagtg tagatggcaa
    30421 ctggtcgtat ccataaatac gagcaacttc ttcgataata tctgcttcga tttggatatc
    30481 ccagcgtctt ggtggtacta ctacggaata aacatactcc ttttcttcat agctaaatcc
    30541 aagtgcttca aaaatctcat ttacttcttt aacgacaaga gatgttccta aatattgatt
    30601 gatgcgttca agtgaaatct tcactgatac gtcttctgct ttgatctctg agcctttgac
    30661 cgcgccttgt agaacttccc cacccgcaag agaaacgatc attgctgcag caacctcact
    30721 ggcttctcca acagtcgcat ggttgattcc tttttcaaaa cgtgcagagg attcactacg
    30781 caaattaaat tgttttgctg tacgacgaat cgaaattgga tcaaataaag cagattctag
    30841 tgcaactgtt gttgtttcat tcgtgatctc tgagtctaac cctcccatga caccagctaa
    30901 agcaactggt tctttgccgt tagtaatgac gagattgtca gttgtcaatt cccgagattc
    30961 tccatctagt gttactaatg tttcattttc ttttgcacgg cggacaaaga tctcttttga
    31021 tttcaatttg tcgtagtcaa atgcatgtag tggttgtccg aataaaagca aaatatagtt
    31081 cgtcacatct actacattgt tgattggacg aatgccttcg ttcatcaaaa gattttgcag
    31141 ccattgagga cttggctgga ttcttactcc ttcaatgatt ctgatttgat aagcaggaac
    31201 tgcttcttta tcttcaactt ccacttgaat tttatcgcta gcaggacgtg aggattctac
    31261 cagcttttcg tcatcgaatg taggagtctg acgataaatt gccccaactt cataagctac
    31321 gccacgcatt gacaatgcat ccgcacgatt cggtgtgata gataattcaa taatcgaatc
    31381 atccatatcc aaataaggaa aaactggatc gccatttaca gcttcttgtg gcatataata
    31441 gataccttca gcgtattctt tcggtataac actatctgaa tagccaattt cttgtaatga
    31501 gcaaatcatg ccatttgata cttggccacg catttttcct tttttgattt ttacattacc
    31561 agcgatacgt gagttaggaa gtgcaacaat cactttgatt ccaaccttca cattaggcgc
    31621 tccacaaacg atttgagaca gttcgtcttc gccaatatcg acttgacaaa tagaaaggtg
    31681 atcagaatct ggatgtggta cgcattcctt gacttcaccg acaacgattt ttttcaagcc
    31741 ttcttctgga accgttactc cctctacttc gattcctgtc acagacatct tatccgctaa
    31801 ttcttttggt gttacattcg ataaatctac ataacgattg agccatttat atgaaactaa
    31861 cattttctta ctcccccttg aactgactta agaaacgtaa gtcattttga tagaaattac
    31921 ggatatcatt cactccatac cgcaacatag ctacgcggtc tggtccaagg ccgaaagcaa
    31981 agcctgaata ttcttctgga tcgattcctg acatcttcaa cacattcggg tgtaccatgc
    32041 cagctcctaa aatttcgatc catccagtgt atttacatac gttacaaccg gcaccaccac
    32101 atttgaaaca gctgacatct acttctactg atggttccgt aaatgggaaa taacttggac
    32161 gcaaacgaat ttcacgatct tccccaaaca tttttttcat tacgacttct aatgttcctt
    32221 taaggtcgcc cattgtgatg tttttatcaa caactagccc ttcaatttga tggaactgat
    32281 gactgtgggt cgcatcatct gtatctctgc ggaagacttt ccctggcgag atcattcgta
    32341 gagcaccctt agagaaatca tgtttttcca ttgtccgtgc ttggactggt gaagtatgtg
    32401 tccgaatcaa tatctcgtct gaaatataga aagtatcttg catgtccctt gctggatgat
    32461 cttttggcag attcatccgt tcgaaattgt aatgatcaga ttctacttca tatccttcta
    32521 cgatctgata gcccataccc acaaaaatat cttcaatttc ttccatgatt tgtgtcacga
    32581 tatgacgtgt accatgtttt acttttctac caggtagtgt cacgtctatt gtttcttttg
    32641 ccaaagctgc atttaacgct tcttcttcta atacttgttt ttttcgctcg atctcttctg
    32701 tcaaaagatc tcggatctca tttgcgaaac ttccgacttt tggtcgctct tctggactta
    32761 gatctttcat cccacgtaat acttctgtga tcggtccttt ttttcctaac gtttcaacac
    32821 gtatttgatt taattcattt aaatcttgtg ccgctgtgat tttgacgagc gttgcttctt
    32881 tcaagctctc taattgtgct tgtagagaca tgtgcttgtt cctcctttaa attccaaata
    32941 caaaacaaaa agacctcatt cctgttaagg aacgaggtct tcgcgttacc atcctaattt
    33001 gcggataaat gacttacacc gcactcttac ttcgttaacg acaattgccg gtctgatttt
    33061 atcagacgaa ctcggaaagt gaacttcatt tttcaaacac aggatctgct ttcagtctgc
    33121 gacagatctc cctgaactgg tttagccaaa ctactctttt tcgtcatcgt tctttactta
    33181 ttcgtatgga ctatagttta caagattttt tttacaaaat caaccgcatt cttcctctgt
    33241 gatccatttt tcgctccaaa cttgtatttg acgcatcgct ttttgcaagt ctgctccttt
    33301 ttcagtcaag agatattctg aacggctctt ttcgctacag gcaaagtttc gagtgactat
    33361 tccttctttt tctaattcct tcaagcgttc gactaatact cgatcactga ccatcgggat
    33421 ttttgccgca agctcaacaa agcgttgcgg accgttttcg agtagtacat cgataatcaa
    33481 tccgttccat ttttttccta aaatagagaa tgttttttca aatttagggc ataaaacgaa
    33541 ttctgtctgt gttagctcca tcatactcac ctcttcccag agtatagcat aatccttaca
    33601 aaacataagt caagtttgct caattataat tatttgttaa tgtttataat ttgtttcact
    33661 cgaagcaaaa ttaggaaaac attttctact ggcttattca aagcttctga cattgcttgt
    33721 tggtaaagtc ttagctgtcc ttgatatttt tggacgattg catctatttc tgctggatca
    33781 tccggatgta aaataaaatc tgttttaaaa tcatagatat tgagatgatc tttttcttct
    33841 aggtatccat cgacgattcc gtggattaat agttcatctt cttgatttgg atagtcttga
    33901 aatacttcgt cagcaggaag cagcatggaa aaaggttgtt ctcgttttac gttttctttg
    33961 ttggcaatca gctgttgacc aagttctgtt tgaaagaacc atataataga agaaacatct
    34021 acttttttcg cgactttttc gtctactaac cgtttcctta ccaattcctg taatttttga
    34081 tggatactct ctgtagttgg catctctaat ggcagtaatt gtaacaaagc atgcgtagca
    34141 gttccaacag cagctgctga cacttgccga tctttttgca aaaattttgg ttctgctagt
    34201 tgttcttgcg tataacgaaa ttgacgggat gctgctttgt tctgactgct ttccagagtc
    34261 aaacgtgatt cttgtgtatc atctggatct tcgaataatc gtttgatttc agatacagat
    34321 tgataacttg tggtttgtga agaagcttga taaggatatt catatgccag acgtttttgt
    34381 aacgaatctg ctaataaagt ttcatcttct ttcatctgct gatctaagtt aaccagttct
    34441 ttttcagcaa gcaactgtct ttgttcaatg atcgattgct gattcatcca tgaaatagaa
    34501 aactgtgcat ttgaatgttg aagaagagaa gtcgaaattt cttcctctaa gtatttctgc
    34561 atttcaggat gacggatcaa tccgtaacca atccaattca tcaagctgct tctgcccttc
    34621 aaacgtagcg caggatcaaa aactaactcc tcatgatcag ctgcttcaga ccacgtttgg
    34681 atcatttgct ctttattttt ataggaaccg acaatgaaaa gcttttgttc tgcccgagtc
    34741 aatcctacat acaatttacg catttcttcc gacaacaatt tgttttgctt tgccaatttg
    34801 atggcttgaa acggtaacgt atcatataac actcgtgttt caggatccat atagcgaatt
    34861 cctgctccaa gtttttcttc aaaagcatac cgattgcgca agtcttgtaa gttgaactcc
    34921 tttgtcatat ctaacaaaaa tacaactggg aattccaagc ctttacttgc atggatcgtc
    34981 ataacgcgaa cagcattatc ttctattgaa atgactggtt ctgctaagtc tttatctttt
    35041 tcttgcattt tttcaatgaa acgcacgaac tggtataatc ctctgaaaga actttgctcg
    35101 taagctttgg cacgatcaac caatgcataa agattggctt gtctctgtgc ccctgctggc
    35161 agaccgacca catactctag atatcccgtc tcataataga tatcccataa caagtcagtg
    35221 atcgaagaac ggcgagcaag ttctcgccaa tgctctagtt gcttgccaaa atgttccagc
    35281 ttagctgcta attcatcttc gtttgatgct tgataagcaa gcacagcatc atagtaagta
    35341 tgtgcacggt tagctaatcg aatgctggct aattctggtt caatcagacc cacgatcggt
    35401 gagcgcaata cagccgcaag cggaatatct tgatagggat tatcgattaa ttgtagcagc
    35461 gagatcatcg tgcgaatttc tgtcgcttga aaatagtttt gagcatcatt catctctaat
    35521 ggaatatcca atgttttgaa aatctctaaa atcgttaagt tgttcttctt tgtaggtgtc
    35581 aagagaacaa tgtctttgta ctctatcgga cgactttttt ttgatttttt atcataaatc
    35641 ataaaggagg aatcaattaa ttgacgaatt tttagtcctg tcataaaaag ttcgccttct
    35701 gttttgtctt ccagtatatc atccgtcgga atctcaatct ctgattcttc ctgttctttt
    35761 tcatagatca tgatttccgg ctcaaactgt tcattctctg gaaagtctga aaatccttgg
    35821 atcagtttgg ctgcttcgtc ataattgatt tgacccactg ctggatccat tagttgttca
    35881 aaaataagat tcgtaaaaga aaggacttct tttctagagc ggaagttctc agccaaaacg
    35941 attcgacgtc cgccttcttt ctttgagaaa ttctcgtatt tcccgataaa taaactagga
    36001 tctgctaaac ggaaagaata gatggattgt ttgacatccc caaccatgaa catatttcct
    36061 tttgtatcat cgggttctct tagccagtat aaaatggctt cttgtaattg gttcacgtct
    36121 tgatattcat ctaccattac ttctttgaat ttttttcgat aatgttttga agcttcactt
    36181 ggcagccata catctttcgt tttttctgtg agaatctgca acgctaaatg ttccagatca
    36241 ttgaaatcca gcacaccttt ttcccgttta cgcatactga aaccgtccat gaagctttgc
    36301 gtgacttttg tcatttcttc gactaacggt agtgctttgt ccgttaattc ttccatttgg
    36361 cttggggaaa caggaaaata acttttactt atctgctgaa tcagtttttt tgctttatcc
    36421 ctcatgccct tgacttcatt ggaaatttct ttcaattctg ctttccgact gctcttaaaa
    36481 gttgaaaaag ttagttgttc caaaccagca taagcttctt ctaaccgatc ttgcgagaac
    36541 gcttcataga tattcttgat ctgctgttgt tctccagcta cttgctcatg cattttttct
    36601 aatccttcac cttgtgctaa ctgagtcatc tgttcatata actgtacaca ttggtatata
    36661 tctgccaaaa ctaaaggacg gatttgtttt tgatataatc gagatttcgc tagcccctca
    36721 ggcaaacgat aattatcgct taactgttct agccattttt gggggtcagg gttggcacgg
    36781 gcaaactcat aaagagaaaa caccagattc gtcaagccgt catctgaacg atcattagaa
    36841 aaattcattg ttaattggaa aaatcgttca tcattttctg cataaagtgc ttctctcagc
    36901 tcgtcccaca catcctcctt catcaagatc gtttctgttt catctgttaa catgcgaaag
    36961 actggatcaa tatcaattaa gtaataataa cgtcgaataa ctgtcaggca aaaagcatgt
    37021 aaggttgaga tattcgctgt gggcaataaa actaactgct tagtaaaatg ctgtctacgt
    37081 acagggtcac tttcgctatt gacggattct tgtaatgcct cttgaattct ttctttcatt
    37141 tctcttgcgg cagcttcagt aaatgtcaca atcaataatt catcgatatc aaaacccatt
    37201 tttagttttt caatcactct tcgaacaagc actgtagttt tacctgatcc ggcagacgca
    37261 gagactaata gattatctcc ttgatcaaaa atcgcttgcc actgatcatc tgtgaatcgt
    37321 tcattttgcg gttttaaagg aatttgattc actcttcttc actccttttc aatattctac
    37381 gcagtgcttc ttccttatct attttctcca gacggtggta attattttct ttcagcatca
    37441 catcaaacgt acagatgctt ctgaatggac aaaattcgca ggcaatccgc tgtttatctt
    37501 tataagctgg atttagtttg atttctccgg aagtaatcgc atctccagct aaccgcatat
    37561 tttcccgatt atgcgccatg aatagttgca gttcttcttc cgtgaaaaat ttgtctttac
    37621 tgaaactacc tttttggtat tcatctttcg catttttttt cactggatag atcagtgatt
    37681 gttcttttgc ttccagtgaa tgatctagta cttctaaaag agcgggatca tcgacaaaaa
    37741 cgccatcata actaaatttt ttcaatgtat tcttctctac atcatctgtc tccgtcaata
    37801 caggattatg aacatgtaaa taatatgatc ctgctggttt aacagccgcc tttccagtca
    37861 aacgtaccgc atccatcaat gctacgtcca gatacgtcaa taattgcata gccatgccat
    37921 aataagcttc tgtgacatcg aatgaacgtc cgctagattt gtaatcaacg acgcttagcc
    37981 aagtatcttc ttgttcagaa gctacatcga ttcgatcgat tttccctcga acatggagtt
    38041 ttccaccatt actcaacggt aattccagac ctgtgatacc ttttgctcca gcaatctgac
    38101 caaatagaat ctctgtctga agaggatgca tgcctgtatt tttgctctgt ttttgcaaag
    38161 cccatgtcac tttttgaatc gtctgtccta actggtagcg gatatagttc attcttgcag
    38221 aactatccaa tatctcaaac cgaagttctc cgaatacttc ctgcagcact ttttcagtaa
    38281 agtctctacg ctgcgcatcg gacatattca ctaaggataa ttggtttgaa aacagtagct
    38341 tgaagaaacg atccaatgat tcatgataaa aatcaccagt tgctgctgga gttagaccat
    38401 aaacagttcg ttctttcaat ttcaaaccaa attgcatgaa gtatttgtat tcacaattat
    38461 aaaaattctc catacgtgaa attgaagtat aaatctcttt tccataaagc tcttccgcca
    38521 ttttttctgg catcgaaaca ggaacattta aatgttcctg actttcaaaa atctgtaaag
    38581 caaaatttcg ccatgacgaa ttcagtacta attctttgag cttttgccag tgctttggta
    38641 caggtttttt ttcatctaaa gctaatcgat aaatcctatt gactgtattg attccgcttc
    38701 tgtaagtccc tacataacaa ttagggtcgc tttcgatcgt caaatgctct tttctctcga
    38761 cgggaacaga taaatattct gtgattctac gcaaataagg agacatcttc agcgaaccat
    38821 ctgtgtcata gctttgtgca taactaagat ataatcgatc tgttccggaa agaaaaacaa
    38881 gataggcttg gaaaggctca aaagagatac tttcctttga tgggtcgaat aaaaactgtc
    38941 catctggcaa ggcctgattt aatacttctc gttcttcact ggacaacaat ccttttgtct
    39001 cttttcggtc tggaaacact tgatcattca accctaatgc aaaagtgacg gcagcttgat
    39061 ttggtcgaac taattccaaa cgattgattc gcacttggtc gattgcggta gggattttac
    39121 cataacttag attttctaga ccacttgtaa tgatttcttg gaacagtgac cagtcaaaag
    39181 ccgattcacc ataaattact acatattcat ccaacagatc aatcagcgct ccccatgtct
    39241 gctcatggtt tcttgccgct tctaagtttc ctctgtctac ttcctgatta cgccaaaaca
    39301 ataattgttg ctgtacgcca ctttggatca aaaattgata aaaaacattt gcggcctctt
    39361 gtcctgtttt gcttttcttt atttttttca aaaatactgg tacagctttc tgaaataatc
    39421 gtctaatcgt atttgactgt tcttccaaat actgtacgtc ttcaatctgt tctgcttcaa
    39481 aatcatacgc cacaaactgc cagtcttttt cacgagtcca ataagttcct tgataattgt
    39541 aagcaagtgc tacattttca gtgatgtcca gttttttcct gaattcatct cgctcttgtt
    39601 tccattcatc aagttcggtt tctgcttccg tcgacagaaa taattcagtt ttgaaaaaac
    39661 gcataatatc acttagccga taagaatagc ggtcaagagc gaacagactg ttgatccatt
    39721 cgatcagcgg atgattttcc atcatttgtt cttcatcgat ataaaaagga attgccattt
    39781 cttgaaagat cggccgaagg atatttccat ataaagacat attttttgtc agcacttgga
    39841 tatcacgata acggtagttt tcttcactga ctagtcgtct gatttcaaca gctaattgtc
    39901 ggacttcttc agttggattt tcagcttccc acaaatggag atgctcttgt ccccctattt
    39961 tgtgtactgc cgctttcttt tggctagatg tctcttccca cattgtttgc agcagttgaa
    40021 gctctgtcgg acgagtctgc tctggtgcaa atcggtccac taatataggg actttccgtt
    40081 ctcttgcact ttgaaaaaga cggaaataaa gctttccagt ctcatgaaag agcgtaagta
    40141 cttctggaag atccgctgta taaggacgat ccagcaataa atcgacaacc aattgcccct
    40201 tttccatcat tgcctgcagt aattgatact cttgaccatt gattcgagaa aaaccactga
    40261 caataaattt gacgttgttg aaatcttgtg tctgcatata atttgctagt atagatagtg
    40321 catcttcatt tgttagtgca cgttgagtca attcgctgtc ataagctgaa aaaatcagct
    40381 tcaagtcttt cattttaagt tgctggtctt ctgcattagg tgaatcacca aataaaagca
    40441 tcaggtcttc tggttgaata tttcctgtac gcaattcact gtagagttct tgtaattgac
    40501 gaataaaccc tcttttattg atttctccgc gaaagattgt taattcttcc tcattttttt
    40561 ctaaaatctg tcgcaagatc attgcagatc ctgattctga taattcattt cctgtaagaa
    40621 gagttgtctg ttgcagcaaa taccaagcca gacgataaaa actaaatact tgaacgtttg
    40681 ttgtgctgaa agtttttttt ccgcttcttc ttcgcatctc cgctaaaatt tcttgttcct
    40741 gttcgaattt gctgtagttg ggaacaagga aaaatacttg gttacttgca tcctggtcga
    40801 gccaagcgga tgcttcgtcg atcaagactt gacggtgatc ttttttcccg tttccaagaa
    40861 taaattgtaa agacatgctt ttcctccttc aacacatgat acggtgctcc tttattatat
    40921 caaaaaatac tgaacatttg ttctatattc ttcaaattat atccttttaa ggttctgata
    40981 tttctacttt tttaagtata cgcaaaaa
//
LOCUS       DADVXV010000016        39976 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.016, whole genome shotgun sequence.
ACCESSION   DADVXV010000016 DADVXV010000000
VERSION     DADVXV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.016"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(150..695)
                     /locus_tag="KB969_000793"
     CDS             complement(150..695)
                     /locus_tag="KB969_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6868804.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(707..1399)
                     /locus_tag="KB969_000794"
     CDS             complement(707..1399)
                     /locus_tag="KB969_000794"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBB6868805.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1418..1702)
                     /locus_tag="KB969_000795"
     CDS             complement(1418..1702)
                     /locus_tag="KB969_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868806.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1715..2278)
                     /locus_tag="KB969_000796"
     CDS             complement(1715..2278)
                     /locus_tag="KB969_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6868807.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2506..3168
                     /locus_tag="KB969_000797"
     CDS             2506..3168
                     /locus_tag="KB969_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBB6868808.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3292..4488
                     /locus_tag="KB969_000798"
     CDS             3292..4488
                     /locus_tag="KB969_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBB6868809.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4589..5965)
                     /locus_tag="KB969_000799"
     CDS             complement(4589..5965)
                     /locus_tag="KB969_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6868810.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(6002..6869)
                     /locus_tag="KB969_000800"
                     /pseudo
     CDS             complement(6002..6869)
                     /locus_tag="KB969_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
     gene            complement(6958..7983)
                     /locus_tag="KB969_000801"
     CDS             complement(6958..7983)
                     /locus_tag="KB969_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6868811.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(8001..8675)
                     /locus_tag="KB969_000802"
     CDS             complement(8001..8675)
                     /locus_tag="KB969_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6868812.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8859..9752)
                     /locus_tag="KB969_000803"
     CDS             complement(8859..9752)
                     /locus_tag="KB969_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6868813.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9826..11523)
                     /locus_tag="KB969_000804"
     CDS             complement(9826..11523)
                     /locus_tag="KB969_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6868814.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11516..12829)
                     /locus_tag="KB969_000805"
     CDS             complement(11516..12829)
                     /locus_tag="KB969_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBB6868815.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12829..16866)
                     /locus_tag="KB969_000806"
     CDS             complement(12829..16866)
                     /locus_tag="KB969_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6868816.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16879..17337)
                     /locus_tag="KB969_000807"
     CDS             complement(16879..17337)
                     /locus_tag="KB969_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6868817.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17635..18153)
                     /locus_tag="KB969_000808"
     CDS             complement(17635..18153)
                     /locus_tag="KB969_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6868818.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18155..18772)
                     /locus_tag="KB969_000809"
     CDS             complement(18155..18772)
                     /locus_tag="KB969_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBB6868819.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18769..19623)
                     /locus_tag="KB969_000810"
     CDS             complement(18769..19623)
                     /locus_tag="KB969_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6868820.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(19620..20531)
                     /locus_tag="KB969_000811"
     CDS             complement(19620..20531)
                     /locus_tag="KB969_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868821.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20572..21906)
                     /locus_tag="KB969_000812"
     CDS             complement(20572..21906)
                     /locus_tag="KB969_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6868822.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            22114..22944
                     /locus_tag="KB969_000813"
     CDS             22114..22944
                     /locus_tag="KB969_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBB6868823.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23188..23506)
                     /locus_tag="KB969_000814"
                     /pseudo
     CDS             complement(23188..23506)
                     /locus_tag="KB969_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23628..23822)
                     /locus_tag="KB969_000815"
     CDS             complement(23628..23822)
                     /locus_tag="KB969_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868824.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(24327..24512)
                     /locus_tag="KB969_000816"
     CDS             complement(24327..24512)
                     /locus_tag="KB969_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868825.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(25362..25703)
                     /locus_tag="KB969_000817"
     CDS             complement(25362..25703)
                     /locus_tag="KB969_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6868826.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(25703..25933)
                     /locus_tag="KB969_000818"
     CDS             complement(25703..25933)
                     /locus_tag="KB969_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6868827.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            26220..26558
                     /locus_tag="KB969_000819"
     CDS             26220..26558
                     /locus_tag="KB969_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868828.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(26763..27002)
                     /locus_tag="KB969_000820"
     CDS             complement(26763..27002)
                     /locus_tag="KB969_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6868829.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(26978..27325)
                     /locus_tag="KB969_000821"
     CDS             complement(26978..27325)
                     /locus_tag="KB969_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBB6868830.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(28057..28638)
                     /locus_tag="KB969_000822"
     CDS             complement(28057..28638)
                     /locus_tag="KB969_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6868831.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(28821..29447)
                     /locus_tag="KB969_000823"
     CDS             complement(28821..29447)
                     /locus_tag="KB969_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6868832.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(29469..30800)
                     /locus_tag="KB969_000824"
     CDS             complement(29469..30800)
                     /locus_tag="KB969_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBB6868833.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(30955..31356)
                     /locus_tag="KB969_000825"
     CDS             complement(30955..31356)
                     /locus_tag="KB969_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6868834.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(31442..31648)
                     /locus_tag="KB969_000826"
     CDS             complement(31442..31648)
                     /locus_tag="KB969_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868835.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(31743..33245)
                     /locus_tag="KB969_000827"
     CDS             complement(31743..33245)
                     /locus_tag="KB969_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBB6868836.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(33263..33718)
                     /gene="argR"
                     /locus_tag="KB969_000828"
     CDS             complement(33263..33718)
                     /gene="argR"
                     /locus_tag="KB969_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6868837.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(33816..34433)
                     /locus_tag="KB969_000829"
     CDS             complement(33816..34433)
                     /locus_tag="KB969_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBB6868838.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            34654..36027
                     /locus_tag="KB969_000830"
     CDS             34654..36027
                     /locus_tag="KB969_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6868839.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            36102..37214
                     /locus_tag="KB969_000831"
     CDS             36102..37214
                     /locus_tag="KB969_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBB6868840.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(37286..38923)
                     /locus_tag="KB969_000832"
     CDS             complement(37286..38923)
                     /locus_tag="KB969_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBB6868841.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(39091..39699)
                     /locus_tag="KB969_000833"
     CDS             complement(39091..39699)
                     /locus_tag="KB969_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6868842.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT        11517 a         8471 c         6926 g        13062 t
ORIGIN      
        1 aagttgttga taataaagag atttattaac gtaaaaagaa taagtttttt taaaataacg
       61 tataaaaaag agcataaaac aaagtcgttt gttttatgct cttcttttat tattttgtgc
      121 tttttatttt atcaaatcac tttgtttttt tataaaattt ctgcgcctag tgtggactca
      181 aaatgtctca atgcccattc atgtccaacg ggatcgaaac ttgccacgga atctttgaaa
      241 atatggagtt tgtatcctag attatacgca tcgactgctg tatgcaacac acagatatct
      301 gtacatacgc cggtcaaata aatatctgtg atctggcgtt ctcgcaaacg gatgtctaga
      361 tctgttccac taaaagcgga ataatgccgt ttgtctatcc aataaacatt ttcctcttgc
      421 tcatagtctt ggtataaact ttttaaagag ccgtacaatt cccgtccacc cgttcctatc
      481 acattatgcg gaggaaataa gcggttctcc ggatgaaagg aatcttttgg atcatgcgca
      541 tcaatggcaa aaacgacaaa atccttttga tcaataaact tctttgtatg agcagtcagc
      601 tttttttcaa ttacttgtcc tgctgtccca gtagtcagct ttccatcctc tgcaacaaaa
      661 tcatatgtgt agtcaatcga gatcaatgcg ttcatcttag tcctccttat acgagatgtt
      721 tgacaaattc gatcaccatt tctgctgatc gtttgcctgc gtcttcgata aattcgtcaa
      781 agctttgtgt cgccgagtga tctgctgtgt cgctcattgc acgtacgatc aaaaatggga
      841 tattgaactg acgagctgtt tgtccaacag cggctccttc catttcgcaa gctaatgctt
      901 cagggaaatt cgttaagatt tctttgattt tatctggcga gtcgacaaat gtatcacctg
      961 taacgatcaa tccttctttt gcgttcaaat tcgttgcttt tgctgcttta accatttcac
     1021 tgcgcaaata tgtgcttgct tcataatata gaggcattcc tggtaattgt cctgggttgt
     1081 agccaaatcc tgttgcatct gcatcaaaat aagctacttt gtctgatata acgatgtcac
     1141 ctacttgtaa gccttcaccg attccgccag ctgaacctgt attgatcacc atgttcacgc
     1201 cgtattgttg gatcaacaga cttgtggtaa tagatgctaa gacttttcct ataccggaac
     1261 gtacgacgat cacttcgtgg ttacctaatg aacctgaaat aaataaagcg cctgcgcgtt
     1321 cccatgataa tggttcgctt aggttctctc tcaaaatttt tacttcttct tccattgcgc
     1381 cgataatacc gattttcatc tttttaattc cttctttcta tataaatgcg attgctaaaa
     1441 aaaccacaca taacattagg ataacaataa taagagattt catcaaaaaa gagttccatt
     1501 tggtcgtctt ttcccgttcg ctgatccttg ttttcgtgat tggtttattc tttttgcttt
     1561 ctttacgata aaagctggca atcttttttt cttcttgctg ataagctgtt tctgcttttc
     1621 gctgtttttt taatgactcg cttgcttgtg cttgttgtcg cttgcgaagt tcgcttcgcg
     1681 taataagcgg tcctttggcc ataagccgat ccctctactt tcctttggtc aatagttccc
     1741 agtattgaat cgcataaatc gtctttgcat cacaaatcaa ctgatctttc atcgcttgtt
     1801 gcgcctcttc aagagttaga tgatacaact ccagtacttc gtcttcatct tgtgctaaag
     1861 gattctcgac cttctctacc ccttgtgcat gataaatatg aaggacttca tttgcaaaac
     1921 ctggtgaaag atacatcgaa gtaagatggc tcagcgactt cgcacgatag ccagtttctt
     1981 cttctaattc tctagctgct gtcatttcgg gattttgtcc ttctcctgga tcgatttttc
     2041 cagctggaat ctccaaaatc actttttcta aaggttttcg aaattgtttg acaagaagca
     2101 gacgatcttg ttcgtcaaaa gcaatgatcc cgacaccgcc aggatgaaat accagttctc
     2161 tcttcgaagt tcctccatct ggcaaacgaa cttcgtctac agcaacatca ataatttttc
     2221 cgctatagat ttctttgcga ctgattgttt tttcttcaaa ttgctcattg ttcagcatat
     2281 cttctcctgc tttctttgta atcataactg cttttttttc atttttcaat ttttctcaaa
     2341 aactccttat tagtttacca tagataaacc ttagattttc tctaaatata gaaaatcctt
     2401 ctttagtccg atactctttc tagtagtccg tatgctaaaa taagtatgta atcgaataac
     2461 gaaaagaatt caatactcaa cgataaatga catggagggt ttattatgat aaaacgaaat
     2521 tggccgtggc ttctagcatt ggtcttgcta tttctctttg tccgaaacaa tagtttttct
     2581 tttgttctag gacttttatt gataggtgta gttttagttt tgtggggact ctttggttcg
     2641 cgcaggaaaa agggaaaaca agaagaaatt cctgcactga ctgacgaact tgaaactcac
     2701 tatgaaaaaa gcggtatgac agcgaatgaa atttcatttt ttcgacaaac aatgaatcaa
     2761 acaaaaaatg agatcaatca attgcaaatg aatatgcagc agacagccaa acttaaagca
     2821 atcgatctcc gccatgatcc agtcaaagca gcgaaagctt tattcaaaga attggtgaaa
     2881 gaaccaaacc gactgcatga agcaagtcag tttctttata cgcatctgcc gaatctagtt
     2941 gatttgacaa ataagtataa tgagatcaat gaccatgaga tcaaaaacaa acagacctat
     3001 gaaaaactag aagaaagcgc gcagatcatc gaccagctgt cagctttaat cgcacaagat
     3061 tatcaaaaat tcgttgctga ggatctagat gatatcgacg tagagatatc tgttgcgaaa
     3121 cagagcttaa agcgtgataa taaatatgaa ccagaacaaa aggattaact cttttgttca
     3181 taaaagaaga ctcggaacat tcagatgatg tctggctgtt tcgagtactt tttctaaagt
     3241 agagacattc atgtaagaat cgagaacaga ttcaacaagg aggaattttt tatggatcat
     3301 aaaccgactg aaacaaaaga tgttacacca gttaacgata cacttgaaga tttattgaac
     3361 aacccgtttt caactccaac agatacgctg accacttcac aacaagcgga gattgatcag
     3421 ctccaagagc aacagacagc tgctcgttta attgacaaac taccggcgga acgccaagaa
     3481 caagctaaac agctagcagc aaaaatcgat gctaatgatg cacagtctgt catcagctac
     3541 ggatcggctg cccaagcaaa attaagtgaa ttctcacaat cgatgttgaa tcatgtgcaa
     3601 gcacaagata ttggtcctgt aggagattcc ttaactgaac tgatgtatcg tctccaagaa
     3661 gccaatcctg acgaactgcg tgccggagaa gggaacatct tccagcgtgt cttcgggaag
     3721 gtcaaacaat cgatctatga agtgacagca aaatatcaaa agattggtgc acaaattgac
     3781 aagatttcag tgaaattaga taaagaaaaa gacggtctgc taaaagataa tctgatgtta
     3841 gaacagcttt accagaaaaa caaagactac tttgatgcac tgaatattta tatcgctgct
     3901 ggagaattga aaatggaaga acttcaaaca acgatcattc cagaagcgat gaaaagagca
     3961 gaagaaactg gcgatcagat ggatgttcag attgccaatg attacacgca attcctagat
     4021 cgtctggata aacgtacgca tgatcttcgc ttagctagac agatcacgat ccagcaagca
     4081 ccacaaatcc gtttgatcca aaacacaaat caggccttgg ctgaaaagat ccaagcatct
     4141 atcgctacag ccattccgct gtggaaaaac caagtcgtga tcgcattgac cttgcttcgt
     4201 caaaaagatg cagtaactgc tcaacgccaa gtctctgaaa caacaaacga cttattgaag
     4261 aaaaattcag aaatgctgaa aatctcagcc atcgaaacag cgaaagaaaa tgaacgtgga
     4321 atcgtggata tcgagaccct tcaaaccact caaaatgatt tgatcgaaac aatccaagag
     4381 acattgcgta tccaaaaaga aggaaaagaa aaacgtcgtc atgcagaagt agagcttgga
     4441 cacatggaag aagatctgaa acaaaaactg ttggatttaa cccaatagat cacctttcgc
     4501 ttgttactaa aacaaacgcc caacaacagt ttattacaac tgttgatggg cgtttttctt
     4561 atctttcttc taacttctcc attggagtct atttctcatt catcttgctg tgtccatagc
     4621 catagccaaa ataaatgatc agtccaataa ccattacgat accgaacacg atccatgtca
     4681 cagtttgcag acgaagcatc aatacaatac aagtcaaaat ggagacgatt ggcaatagcg
     4741 gaacgaatgg cactttgaat tctccagctt ttggtttgcc aaacattttt ctcaacttca
     4801 gtaagcctag actaacaagc atcaaatagg cgagcgccat gatattcgtt agttccgcta
     4861 atacattcaa tgggaaaaat ccggcaaaga atacagctgc cacaccagcg gcataagtcg
     4921 cttttttcgg tgtacgatgc ttttgatcga tttctgtcat aaacttagga agtaagccat
     4981 ccttgctgac agcaaacagt aaacgagcaa gtgaatacat catcgagatc gttaccgtca
     5041 gtagcgttaa aattgcccct acagcgatca ccgcgcccac tgttccatgt cctacatacc
     5101 tcattgcaaa agccactggg tcattgactc ctagttcagt atacggaacg attcctgtca
     5161 agatcagcgt cacgatgatg taaaggacag tagcaatcag tatcgaacca atgattcctc
     5221 ttggcacatc tttttgcggg tttttgactt cctcggctgc cattgcaacg gcatcaaatc
     5281 ccaagaaagc aaaaaacaca agagctgcac catctagcac accggaaaaa ccaaaaggca
     5341 tgaatggctg ccagttatca ggtttaacga aaaatattcc tacaatgata aacaacgcga
     5401 tgataccaaa tttgacatat accatggcat tattcaaacg taatgctttc ttggcttcaa
     5461 gcgacacgat gtaagtgacg aatatcacta cgagcaccgc aatcaagtca atgtatgtac
     5521 cattttccgg attgtacccg ccagttaatg cttgtggaag ttcggcccct aaacttttca
     5581 aaaaaccttg catatagcca gaccatccgg aagcaacaga ggaaaccgct agtaaaaatt
     5641 ccccgatcaa caaccaccct gtcagccagg cagcaaattc accaaataca acatacagat
     5701 aggcatatgg cccaccaatc actggcactc gcgaagcaaa ttctgcgaaa cttagtccag
     5761 acaaaatgac aacgattgca gctaagacaa atgaaagtga cagtgctgga ccagcatttt
     5821 gattggccgc aacccctgtc accacaaata ttcccgtacc gatgatcgca ccaattccaa
     5881 gcatgatcaa atcagacgtt tttagttctt ttttcatctc actcgtatga ttgagattga
     5941 tctctttctt acgaaacaaa tccattgaag ttcctcccca ttttaggttg gaaaacagcg
     6001 attaaactgt tttcatatac cctaaaaggg ataccaccta aaatgactaa aaggcaacca
     6061 acaataacat aaatgagctc ttttttcgtt tttctttcgc caaggatgaa aatcccacct
     6121 aaagtagaga taatgatccc catttgtgaa agtgagaagc caacagctaa accaagtgat
     6181 ttgactgtta gaagcatgca gatgtttcct aagccccata ataatccaca gatcatgttt
     6241 ttccacacaa actgatcgac tttaacttta cggaaagcaa agaagcttgc gcctaagatc
     6301 attccgatac tttgaggtaa gataattgac atcgcatcca aattcgccca gttgacgatg
     6361 atggtatata caccataacc aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa
     6421 tcaagcattt tattatctgt atctattttt ccttcgtcat cttgtcgggc agtcaaatac
     6481 gcaccgctta caagaagagc taaagcaata ataccgtata cataatcttt cgtttgtgtc
     6541 cattcatgga agaaaacggc tcccgcaatc gtattcaaaa ttaattgaaa accagtagac
     6601 aatggtagcc ctacagaaac acccatgtac ttcattccat ggaactgtcc attttgtcca
     6661 acactccaag ctaagccgga taaaaatccg atcaagaaaa tccaaggggt gattacagga
     6721 ctaacaacga aaaagacaac taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt
     6781 tgttgattgg catcgccacc aattttacca cttactaaac caatactacc ccatgccaac
     6841 atagggacta atgctattaa aatttccata accaatctcc ttttatttca catgataaga
     6901 aacttatcag cgaaaacgtt aacaacacaa gcactttttt tcgtttctaa cgattttcta
     6961 acgtttttca ttataaaaat ttaagattgg gaaaaataaa gtcattgttg tcccttttcc
     7021 ttcagttgat tcagccgtca aatggatacc taatttttcg gccagatttt ttgctaaata
     7081 aagtcctaat cctgttgaat gtgttttgct aagtcgacca tttctcccag taaatccctt
     7141 atcaaagatc cgtttcaagt cttccgctgg gataccgatc cctgaatctt taactgaaag
     7201 gctgactcct tgcgcttcct tttctatgct cacaatgatg tttccgtgat ccggcgtata
     7261 tttgatggca ttactaagca attggttgaa gataaaagcg atccatttag catcggtcaa
     7321 aacagtatga tcctcaccaa cgatctcgta gcgaatattt ttttggataa aataatttgc
     7381 ctgactgcgt atcacaggct gaatgattcc ttttagtcca tattcttgga tgaggtagtc
     7441 ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt tctacgtatt catcgatttt
     7501 tgataattca ttttctagta atgtatactt ttgatcgtca atatcgaact cgatcgaacg
     7561 aactagcaat ttagaagcgg aaagtggcac tttgatttca tggacccatg agtcaatata
     7621 atctttttgg tcttgttgat tactgattgc tgattgcatt acttcttggt gttcacggat
     7681 cagctgattg atatattctt ctaccagttt ttcttcttct gtcctcccac cactcaaata
     7741 attttgcaaa ggggaagttt tttgtatgtc ggctaatttt ccccaccatc ttctcttgct
     7801 caagtaacca cccagcagat aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc
     7861 aattgtgctc aaatcaactt tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc
     7921 aataaaaaac agccatccca agatcaatgt ccactgatct ttcaaatatt taaaaaaatt
     7981 catcttaacc gctcatcctt tcagggaacg atatatccct gtcctacttt tgtttcgata
     8041 tatccttgga tacctgcctg ttcgattttt cggcgtaacc gattgatgtt gactgtcaat
     8101 gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt
     8161 aagatctttc cattgtgctt catcaaaata aataatagac gatattcatt tttgctcaaa
     8221 tcaatgatct ctccgttgat ttccatactt ccgttgtcaa cattcaacgt aatgccattg
     8281 tggctcatca tttcactaga taattctgtg tagttgtaag aacggcgaag taatgcattg
     8341 atttttgcaa tcagtacatc gatttggaaa tgttttgtca caaaatcatc tgcccccatg
     8401 ttcatagcca tgatcatatc catattcgta ttcctgctgg agataaaaat gatcggtact
     8461 ttcgatactt cacgtatttt ttgacaccaa taatagccat ccaaaacggg aagattaata
     8521 tctagtaata caagctgtgg ttcttctctt tcaaagtctg agaacacttg attgaaatcg
     8581 gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg
     8641 atctcttcgt cttcgactac catgattttt gccataaaaa atccctccat ctttcttctt
     8701 gctactacaa tatcaaagaa gcccttgtga aacaagttgg cttacctgga aaatgtcatt
     8761 ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc
     8821 agcttaaatt tattatgtta ttcttaataa ttggtctatt atctgttatt tttctttcgt
     8881 tgtttttgtc ttttaaattt tcgataacac caataaccga aaagcgttag cactagcaat
     8941 atacctagaa ggagtataag taatcgataa agatggtatt tttttgtctg ttctatcttt
     9001 gaagagactt cttctgtaaa gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc
     9061 acggtgtaag gtgtacaagt gataagtgtg actagatcct gcttttctct aattgctaat
     9121 gtatttgttt ttgttggaag gacaacaatt ttctcaacga cttcataagc gagcatccga
     9181 ccatacactt caagatagaa tcggtcatct tgctccattt cttcaagatc cgtaaagagt
     9241 tttttctcag caataccgct atgggcggta atcacggaat gtgtactctc tcctccagtt
     9301 ggaaaagagg tgccttgcag gactgtcgct cctctatcta acaaaagatc attcgtttca
     9361 tcaaataaag gcaagctaac attgattttc ggaatataga tggctccgat catatgttgt
     9421 tcgtaatatt cttttcctgg attttggaca tttctaaccg cttgctcaaa aggatctttg
     9481 acttgtccca ttcctgggat tactgatgta tgagcaagcg tctgattttt cttttcatgc
     9541 actgctaatt gttgctcatg tttttcttct ttatcgcgtt caagctgctt ttgataattc
     9601 tcgatccttc tttgatccaa ataattgctg agagcatctg ctaaaaatgg atatgtaaaa
     9661 actgcagctc cggcaagaaa catcactgcc ataaataatt gtaataaaag actgatttgg
     9721 gtttgaggtc tattacctat tttctttttc attttcttca ccttcttatt taaaaaaact
     9781 gcagcaacct ttataaaacc gattgctgca gcttattttt gttgcttata cttcagactt
     9841 cattttagat ttacggtacc agctgtacgc tccaatcatc aaacttattc cgattagtaa
     9901 gaatgccaag agcccgttcc caccagtagc aggaagtgac ccgcgtttca tattcggtac
     9961 tctttctggc cctggatttt ctactcctac gatctgaatt tcttcattat agcttccata
    10021 agagatgata aattcagtaa aggctgcctc acctgttgga agtacataac cttctggcgc
    10081 catggtctct ttcatttgat aggttccata atctaaccct tgaacctcaa agtatccatt
    10141 tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc
    10201 tgattcataa acagctaaag gcgactcccc tttataaaat attgcgtatt cagaacggtc
    10261 ttcattccac aattcgaatc ttgcatcttt aagcaattca ctgcttgatg catcatattt
    10321 ttcaaacttt cttccacctg ttgtgacttt ctctggcggc tctactcctt cttcataatc
    10381 aaattcatca tttcgtccga tttcaataac cgctgtgttg ttatggaaat catccgcttc
    10441 tagttctgtg gaaaccttca aattatacgt gatcgttaaa tctcctccac gtgcatctgc
    10501 taatctacct aaagtatcta ctttggctac tccattttct tctgtcaaaa tcgtcacgac
    10561 aaacccgttg cttactactt ctactatata atcttgtcct tttgttaaaa tcgtctcgcc
    10621 ggctcgcact tctatttcct gatcataata agttagacca actgtaggcg tatctgtgat
    10681 tttgtaattt ttgataacag cgcttccgtt ttcaaggaca gaatcgatga aataaggaat
    10741 aggtgctgtg atcgtgtaag aagccgtttt tcctctttct agatcaatat aagaaatcgt
    10801 ttcttgttct ccagcttcat taataatcgt tacttgtcta aggtcgcttt cctctacatt
    10861 catctgttta tctgcttctc tgatttcgtt tttcggatac aaatgcacat ctgtattgta
    10921 tgtgtctttc catgtagaac catcccacac gccatccacc atatcaggca tcatcactgg
    10981 catcataaca accattggag acgcgattct ggaaatatga gctggcgaat aagtttctaa
    11041 gaaaagatag actttatctc tagaagaagg tgcttcttcc gtcacttgga cggtagagaa
    11101 taccgcttct ccagcttcat tcgttgtttg tttgtcaata cttgtcagtc gatattttaa
    11161 aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc gcttcggcag aattaagacc
    11221 gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa tcgtaatata cttccgttac
    11281 gtcaaacaaa tcaaaatcga ctcctggaat attttcttca ccaaaatccg tagaaaccaa
    11341 tccgctattc ggtcgttctt ccggaacaga tgagaaacct tttttgtgta atgtaatcgt
    11401 cacttcactt ggtttttgtg cgacttcttc ggctttgact agttttccgt tcccgaaaat
    11461 ccctattccc gcagtaacga gtaacagtac actcattccc gtgacaatca tttttttatt
    11521 catttttttc tccccgttct ttttttatta ataaaacagc acctaacaat aaaagaattc
    11581 ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg gaatacggac cattttcctg
    11641 attgacctgg attgcttgga ccactcggct ctttcggttt gtccgttgtt tcttttacgg
    11701 tctcgttata aacacgtggt gttgcggatt cataggcaga gactggaact ttcccggatt
    11761 ctaattcagc catctcctgt ccgttaacta ctacatattg tggttggcct tttgcatcca
    11821 cccaaaattc agggatgatg acctcgattc tcttacttgc ttcatccatc tcgtaacctt
    11881 ccacaccttt taattcttca aaataatagg tgccagaagg caagaaacgt tgtcctgtcg
    11941 taacaaggcc ctctttatcc gaaatgaatt tgcttacatt tttgtcattc aaaggatcat
    12001 tgtctgctgg tttgatccat tgatttttca agtcattagc aggagccata tctaaataat
    12061 atttcccccc ttctatcatc tgatatagag caaaaacagc accttctaat ggttttcctt
    12121 tttcagttgt tcctctttga cgtccatact tgaagaagta tggatctctt agataaccga
    12181 catttttagg atagatatga atctcttgca gttcctcggt tgattctgtc gggtgataaa
    12241 ttggcaaaat agcagcaatt gggatagctg tctgatcgat atcaacatcc aatccaactt
    12301 ctggatcaat cgattcttcg aaaatcaaat aaactgcatc ccgatcttgg tttttcttag
    12361 gtgctttgat acgtgcaatc ccgtctccta atccgccaac cgtatctttc ccagttgtta
    12421 ccgaagtccc tatttggaca agcctttctt ctgtgattag ctgacggata ttgtttctgt
    12481 tcgtttcagc gatttgctgg acgaattctt taggagtcat gttttcagca gctttttttt
    12541 catgataata atcggtcatg tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct
    12601 gtgaaatgat atctgctgtt tcccctgctt cctcagagat agccaagcca tcattttcat
    12661 ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat ccgtttatgc aacacgaatt
    12721 ccacgacatc ttcccctgat tcttctgccg acatcgcatg tggaagaagg actgctgcaa
    12781 gcggtagtaa aacaagtaat tgaagcatca aacacaacag ctttttcatt accttgctcc
    12841 ctccttttta gattgtctga caaacaaacc ataggctgct cctgcaagcg ccatgaagaa
    12901 tgcagcaagc aggatataga ataatcgtcc ggatcctcct gtagcaggca acggattttc
    12961 aggatcgttc ccgacactaa gctgtaatct gattcgattt gtctccaaaa gttcatattc
    13021 taactcttgc tgtagatcag gcgtctctgc ttcttcgttt ggataatacg aaatctcaac
    13081 ttttagtgta cccgcttctt ttcctggaac tacccgatca ttttctatgt caggttcttc
    13141 tcgataacta atttctaaaa taaagtaacc tggaagtttt ctatagctgt caggtgactt
    13201 cacttccttg atccgataga ccccttccaa caagtctgaa gcattgaata gggaagaatc
    13261 gtttggatct ggtgccaagc ctccctcgat gatttcatac tctcctgcac tattttgttt
    13321 ctcaattgaa aattctgcgc cttcaagacg tcggctattc atactgtcaa ttttcaaaag
    13381 ttccaaatcg attggcgcta gttcatcttc taaggttact tgtagtacac catcgatgat
    13441 ttcatagcct tccggcaagg gagcagtttc gtcttcgatg accgtatctt caatgataaa
    13501 cttaccttct tcattcagtg caaactggaa cacttgatca gatagccgat acccatttgg
    13561 tgcgacagat tccgagacct catattcacc aatagacaga tgcagaggtt ggtcgtaatt
    13621 taaatcgaca tacttttcta ctcctacggc acgagaatag aagtatccga tcccaggcaa
    13681 acgtttcgat tcttctggtt ctaacggatt accagtgtat gctcgataca gcgggaagga
    13741 agaatccccc actttcctga tatcgaaacc tgcaccatct aatgtatggc cttcatggtc
    13801 taattttcta actcggatct cccgataatc aaacgtattg taagcagtga atgctaccca
    13861 taaacgatcc tcttcatctg ttgtatacgt gagatattgc caattttctt cacctgtttg
    13921 cttgagttgg atagtcccta tagcattatc gtaaagtcgc aagatccatg tgtcattttc
    13981 atcaggttct ttgaaacctt ctgggttctg gctctcaatg attttgtatt ctgcatagtt
    14041 ggtagtttct tcactatcct tataaacaaa tgaatctggc tctccgattg gatgaataac
    14101 tttctcacca tccacgatta catatttccc gtcttcatct actgaataga acgtgagtct
    14161 ccctttctct tcctctactt cgttcacacc agaaagccct ttcgctactg gatatccgat
    14221 ttccagtccg ttaccatctg tttcataaag ttcaaactct gcgccattga ttggcatatt
    14281 actgccttca attagtttat tgatattcat gtggattggc ttgaattcat ttcgcatttc
    14341 cagtttgaca tacaactcat catactctgt gccttctatg ttaggctctt gtacaacaga
    14401 aagcttgtga tattctcctt cataatagga attcggatct ttaccttccg gtccgccgac
    14461 tctcgaacca gatgtatatt catctacaag ctcgtagtga cctaacatct catcttcgtt
    14521 ggctgcatat tttttgattt ggaattgata cgtctcatct actaactgat aacgtggtgg
    14581 tccagcgatc tctctgatcc aaaatatgtc gctgactgct ccagtttcat ctcctaaaat
    14641 cggcatcttc gtttcaaaga tcgctattcc gtccgtggta gttttacttg tttcgattgg
    14701 ttcggcttcc ccactctctg gattttggtc atataatgca aattcgactc cagccaacgg
    14761 ctcgccattt tgacccttct tgctgacttg gaaattacgg cctttatgtt cgtaacgaat
    14821 ggaagaagat gggaaataca tccgtccagt agtgatatca ttctcataat cctccaggtt
    14881 ctgaatatag gccatattgt tcactgtgca aaaatttccg tcttgagctc ccgcatcaag
    14941 ttttacttgg tacttgatcc tgaccatttc cccttcacct aaagaaatcg gagaaaattt
    15001 ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc gccactactt ctggtggggc
    15061 ttgtccatga cgttcttcat cccatatttc tggctcttgg tacttcatgc cgttttctcc
    15121 tggatctaga tggtaaaact gaatatctgc cgatctgcca gctccaaatg gtgagacatt
    15181 aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat
    15241 atcctccaag gctgtaacaa tgtcattctt gttgttcgca ttgtaatatc gcggtgttac
    15301 gccatcttct tctaaatcag caatattttt caatacattt cgtccaatag catctagtcg
    15361 ttgtctcccg ctaacgtttc catcgattcc taaaccaatg gagaagatac ttggcgggtt
    15421 ctcttgatac ttgtttttca gccaatgatg ataagcaact gtgttgatcg cagatgactt
    15481 ttcttgcgaa gtaggactgc cattcgtatt gttattagaa gaaccatcac caacccagtg
    15541 agtcgcttta ttatctcctt cttttacctc tccataacga tagtgtacat ttacttcatc
    15601 ttctggacgg ttaaagtcag atgcataggt aactggatga gtaaaccctg cattagaagt
    15661 attcccagaa aactcctcaa aatttctgaa caaaacgtca ttatcttcag caatcttatc
    15721 ttccatcaca gtccagttgc tccaagctcc attagtgctc gtacgataac ttgactgaat
    15781 cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt tttctggatt
    15841 tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa gccctagtgt
    15901 aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg
    15961 attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt tattgatagc
    16021 tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg ggtcagagag
    16081 cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag tttgactatt
    16141 ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa cgatatcgat
    16201 tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt aaagggttgt
    16261 tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt ctacccattt
    16321 tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt catttcccca
    16381 aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg atccattatt
    16441 agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac tatcatcgat
    16501 caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat tgctttgtgt
    16561 ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcgggtagc gatgctgttc
    16621 gttttcaact tctccgctag gatagatata ttcatagggg tcttgcgtag ctgttggccc
    16681 aagacgctcc aaaataccgt tgaataactg gcgttgaatg cgctggagtg cttgaccgct
    16741 gggtacgatt ggttcgtcca gcttttccat ctcattttct tcgctacgtt gaatttcagc
    16801 ggaatcttct gtatcagttt cattttcttg taattcttgg ttatctattc tttcatcaac
    16861 caccacttga agaggtagtt acccttcgtt cacatcgggg atcttttctg tttcaaaaat
    16921 caatgtgccg gtttctgctt cttttgaata aacttttccg acataccatt cttgaccatc
    16981 gatcgtctcg acttttaggt cttctccatc ttcatcatag gaggatagac ctgttccacg
    17041 aacgtttttt acggtaccaa tcccggcggc tgccgcatcg attgctaaac gtattctacc
    17101 ttcattggca ctttcctttt tttcaaaagc cagatgccat tcaagggttt cttctttttc
    17161 aatatacttc ccttcaattt ttgcatagtc ctcatctaag aatacctcat cctcctttgt
    17221 ttctgttgac tcagcagcta catccagggt cgtcatatga tagactgact ggaaatatgg
    17281 tccaaatagc aaactgacag ttactaactg caaaagcttc aattttaacc ctttcacatc
    17341 cttatactcc tttcaaaaat atttgtcttc tttcacaaca atcaacaaaa caatgcccat
    17401 ctaattataa tttaatttaa ttttaatttt aaatcaaatg atatcctttt tagttaaaaa
    17461 acaccaatta tacaacattt attattaaaa ttaaattata aaattttata acgttctcat
    17521 ttaacaaaac ttaagttatt aagacaaatg aataaacaac tacgctttcc tcgaaacaaa
    17581 aaaataaagc acaaatgcgc atttacgcac tcatgcttta ttcgtacaat taattcagat
    17641 aacggcagcg cataggatgc caataacact tcctaaaata gctcctccta aaatgtcagt
    17701 aggataatgt aaaagtaaaa aaatcctcga ataagcgatc aaacaagcaa ataaaaaggc
    17761 taatattcct gcaactggac ttaattcgaa caacgcagct actgataaaa aggctagcgc
    17821 tgtatgtcct gaaggaaaag aagaagtctt cggtttactt gtgtaaagga caagccgacg
    17881 atttttttca taaggtcttt tccgtcttgt cgtttttttg ataaaaagca aaccaacaaa
    17941 aaaatagatc aaactgccga taagaatggc tagaccatat tctctagtat caggtatcaa
    18001 gactaaaaca gcagcaagga gcaaccaaat aaaaccacca ttagagatat tactgataaa
    18061 tttcaaaaaa ttgatttttc gactatccgt tttccgttgc ttggcgaact tgttgataat
    18121 actatcatcg attttagcaa tcaaacgcaa catgttattc ctccttttta agaacctttt
    18181 cttgcgtacg atggataaaa agcaggactt gaaaataaaa caagaaactg aaacctaata
    18241 aagcaaaata gattggtcct gcaaaccaga atgcgacaag aaggatcaac gtgcctgcca
    18301 aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa aaatgcagta atccaagaag
    18361 cttctttttg ttccagttga agcaagattt tgtaactaaa gagaagcgcg cttaatagaa
    18421 gcaaaaacaa cgtagtatac atcaatgtat agccaattcc cccaccccaa tagcggaaaa
    18481 tctgataatc gatcaataga agaagaaaat aaacacttgc taaactatct tgctttccat
    18541 aaagagagaa gttctcacga aactttttcc agaatagtga accgagcttt ttctcttcat
    18601 tttttttgta atgataaatc atatacagaa ctgttcgact tgcagttcct aatgtgaaaa
    18661 caggcaagac gcacaggaac catagtagct gtaaatggat aagacgtgga atccattcaa
    18721 tgatttctaa gaaataatca ttggcttttt taccaatcga tcgattcatc atccttttga
    18781 acctcctgtc aaatccatcc cttcaatgaa ataacgttgt gcaaaaaaga acagcaaaat
    18841 cgtcgggatc aagacaagtg ttgctcctgc catcagataa ttccattgtg tcgttgcttg
    18901 gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt tcttgatctt ggatatataa
    18961 cagaggacct aagaaatcat tccaagctgc gttgaaggaa ttgatcgcaa tggtaatcaa
    19021 ggcaggtttc gtcaatggaa gcatcaaatg actccaaata tacaaatgat tcgctccgtc
    19081 gatttcagca gcttcgatca attcattatt gatcgataag taaaattgac gcatcagaaa
    19141 tatattgaac gcattgccga agaacgatgg aacgatcagg ggcaaataag tacctaccca
    19201 gccgatcttg gagaataata catattgagg gatcatcgtt acaaaccccg ggatcatcat
    19261 cgtagaaaga accaaagcaa acatcagctt tttcccagga aaatcaagct tcgcaaatcc
    19321 ataagcaata aaagaatttg aaaggacatt accgatcact actagcacag tgatgaataa
    19381 tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc gtatccagat agttttccca
    19441 tacgattttt tctgggaaaa aggtcggagg ataacgaacg atttcttcca ttggtttcaa
    19501 tgaagtaaac accatccaaa gcaatggaat gatcaaaatg attcctatta ctgtcatgag
    19561 gacataactt agtatttttt ttgtttgccg attcacactg gtctttttga aataatccat
    19621 catttgccgt cacctccaga ataatagacc cacttaggtg caagcttcaa attgacaaac
    19681 gtcagaacca acacgatcag aaacaggatc attgacatag ccatcgcata acccatatca
    19741 aaagctacga acgccttgtt ccacatatgc agattataaa aaagcaaaga atttgcaggt
    19801 ccgcctgttc catttttcgt catgacataa gcttcttgaa aaatttggaa agaaccgatc
    19861 gtagaggtga tcacatcgta aaaaataata ggagtgatta atggcaaagt aatacttttg
    19921 aactttcccc aaacgcctgc tccatcgatt tctgctgatt catataaaga tctaggaaca
    19981 ttttgtaatg tagctaagta aagtagcatt gctcctccag aactccatat tttcatcaaa
    20041 atcaacgcag gtttcgtcca ttgtggatca aacagccaag ctggtccagg gatatggaac
    20101 cagcccagaa atgtgttgat caatcctgca gatggagaaa gcagctgcat ccataagatg
    20161 tagactgcta ctcctgataa gactgccggt aaatagaaag ctgtacggaa tacactgatt
    20221 cctttgattt tttgattgag tactgtggct aaaaacacac tgaaaatcgt cgtcagcggt
    20281 acattgaaga tgacgaaata aacggtgttg tataacgatt tccaaaataa atcatcgtga
    20341 acgaacattc ttttgaaatt tgctagacca atgaaattca tcttggatgt caaattataa
    20401 tcggtgaaac taccaataac tgaaaaaagc ataggcccta gcataaatac caagaacccg
    20461 ataataaaag gcgagataaa taaataggcc catcttgctt cttttttctt tcggatagat
    20521 aaacgcttca aattttcttg cctcctctgt acctagacag tcaaaaatgg attattgatt
    20581 ttgcttgact aagttttcta ctgctttttg tgcatctgcc aatccttctt ttggtgattt
    20641 tgttcctaaa agaatctggt caatctgttc attcactaat gtcgtgtaat ccggagcatc
    20701 taaaggaact ggtgtgatca ccgtattttt aaagttttcg tccgccattt gatagatcat
    20761 ttttccttta tccgttaggt tgtcattatt cactaaattc tcattggctg tcttgctcgc
    20821 catgatatca aaactttttt cgccgaattt ttcttgtact tctggagaag aaagatattt
    20881 gatgaattca taagaggcct caggatcttt tgctccgtat ggtacttcca agacgaatcc
    20941 gccaccccac gaccaatggc ctgaaccttc ttctttttct gggagctgca tcacgccaaa
    21001 atcaaaatca tccggtgcat tttccatcaa actagagtaa taattgatat tttgggcacg
    21061 catggctact aatccggaaa taaatggatc agatacacca gacccaaatt cggcttctaa
    21121 tttattgatc gtatttttcc cataataatc ttgccagtct tggatccact ccaaggcttc
    21181 cactttattt ttagtatcaa tcttgacttt ttcatctttg tcaaaccaac tagtcccgtt
    21241 atctgcgttt agcgcccata catcagcccc taaattccat aatggataaa aaccgatgcg
    21301 tgtaaattct tttccttctt ttttatctag tttacgtgct gtttcttcta attcatccca
    21361 agttgtcggt agatcttgtt cactgattcc agcttcttta aataactttt tattataaaa
    21421 aatgacttgt gtatctgtat tgaatgggat cgcataagga tcaccttcat attctactgt
    21481 atcccaaagc tgcggataaa aatccttaga agtgtctttt tctacatatt tggagagatt
    21541 agttgcttgc tgtgcttctg ctctttgggc aacggaattt atgtcctgta caataacatc
    21601 gggtgcattt ccagctgtta ttgcagataa agatttagtc cagatgtcac cccatggctg
    21661 atacttataa tttacatgga tctcgttttg tgattgattg aaatcctcaa tgatttcttc
    21721 gatagcttct tttcgtgcac cggatcccca aaaggaccag aaatcaatat tttttcttcc
    21781 atcacttgtt ttttcagaag aatttgctgc acttgaactg gcatcgcttg cattacttga
    21841 tccgcatcct cctaataaaa acaatgctga acttgccagc aaccctgtaa acaataattt
    21901 tttcatattt tacctccaaa ttttaatgta accgatgccg gttttaatat aacgatatca
    21961 ttttgttctg aaaataacaa tttataaggt atgattctaa aaaaattatt aatgatacca
    22021 atactttata taattcgcga gcgctttctt tgaatttttt aatctttcgt agcagaatga
    22081 gaatgtatta aaaatagatt aggaggaatt ttgatgttta gacaccagaa agaattgcag
    22141 tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga aatatctgca ggagctgatc
    22201 ggcggccaat atggcgagat gagtgtagct atgcagtacc tgttccaagg ctggagctgc
    22261 cgaggagaag aaaaatataa agatatgctg atggacattg caacagaaga aatcggccac
    22321 gtggaaatgt tggcgacaat ggttgctcgt ttattagagg gtgcgcctgt tgaagatcaa
    22381 gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta tctctggaat gaatccacag
    22441 cacgcgatcg tagctggctt aggacctcgt cctgctgaca gcgtgggcaa tccatggagc
    22501 ggtgcctata tcattgcgag tggcaacttg ttagcagact ttagagctaa tttaaatgcc
    22561 gaatcacaag gaagacttca agtagcacgt atttacgaaa tgatcgatga tcgtggcgta
    22621 aaagatatgc tgtctgttct ccttgcaaga gatagctatc atcaaaatct atgggaatgt
    22681 gcagtgaaag aattagaaga aaaagaaggt tcaatcttag tcccaagtac tttcccgcgt
    22741 gacaaagaac gaaaagacat tgcttatgac ttctataact tctcagaggg agaccaaagt
    22801 agtgaaggtt cttgggctag tggcaaagca ctggatggcg aaggcgaata tcaatggttg
    22861 aaagaaccta agatcgaagg cgctgcacca aaattagaac cagtaacacc aaaaatgtat
    22921 gggacacctc cattcaagaa ataaatatct acccgtagaa acacccgttt tttgttccac
    22981 acgctttgtg agcaaaactg actaaagtca ttaatcataa ccacccttca aaagggtggt
    23041 tttctctaga gctataagct caaatcaccg gccagcgcct aaagacgctg gctttcatat
    23101 tttatgttca agccatattg cctttgccag ttttgcccac ctcttaaaag gtttatgtac
    23161 tactccttag cccttaaaag gatcgtctta ctctcgtaca ctcagcttat ctaacgcact
    23221 atcatgtttt tcttgttctt gaatgtactt tttgatggtc gcttcatttt gtcctacttt
    23281 tgtcacatag tatccttcca cccaaaagtg tcgataccca aatttatatt ttagatttgc
    23341 acaatctctt gatgatctcc tgaatattgg ctcgatattg attataaatt atttttcttc
    23401 tatactttgg tgtgaataca atgtggtatt tacacatcta ctttgtacgg gctaaactat
    23461 ttccctttat tgctccaccc gcatagcaag tggttttgta tttcaatcgc tcggcgcgct
    23521 caattaggtc taaagacaat aaatctaaaa acccgctgct tcactgacag aaacaacggg
    23581 ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca atctatttta tttttttgat
    23641 tttttataaa tggaaaatgc ttcaagaagt ccaagaaata aagccgtata aaaacaagaa
    23701 cctatgaaat ctttatttat tagatattca acagaaatcc cgataacact agccaacaat
    23761 atatttatca gaagtgtaaa ataaggatgc tttttataga atagaactag tgttgttttc
    23821 atagactctc ctttcttcat atttccaatt aatcacaaat tcacggcatt actagaaaaa
    23881 ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc cctacaaacc aggccatctt
    23941 gtgtttaata actataccaa atctaaggta cctctaaatc taaattccat ttgtggcggt
    24001 gacctccaat ttttaactct tctatctccc atccagtata cataaccttg atacttcgac
    24061 cacttatata tcgaacacac aaatacctat ccattgcagg agtactacct aacttagttg
    24121 ctacttgcat ctaaataaca gctgaaaaga taggacttac tcttagtaaa gtatctgaac
    24181 tattaatttt taaactatca tttttatcct caactacatg cacatctgtt gcaacttcac
    24241 tttctgtctc atccagataa atgattaagg aatcgggaat tgcaatatct tcagctgacg
    24301 ctggaatagt tgagctaaat tagtcatcat atctttatta taaaataacc aacagcaaaa
    24361 aatacaatga aaaacaaact tggaactaat gtatcattaa taaatgttga aaaattcagc
    24421 aactcattac tgtatgattt tagcagccca accaacatat accctataaa agctaataag
    24481 atggttagga atcctttaga atttttactc attcatagac acttccttaa ataactttta
    24541 ttatagaagg tattgtaaat aataatattg acaaaaagtg actcaaaata aaaaaaacct
    24601 tacattatac tggaatgaac tgtattgata gtgtacctaa aagctctact gacataagat
    24661 cgtgtaatcg gtaaagtaat tttattaatt atacgggatg taatcaatta gagaataaac
    24721 taatcataaa aggtactttt acattcataa ttgtcgcttt gagattctac tttggttcac
    24781 tatctgaccc aattgcacat tttcgatcat tacaagtatt ggtgtcgtta gaacaactaa
    24841 ataaaaacta gcggtagatt tttcagaatc tatgctaatt tctgtatgga tgttccagtg
    24901 atggcaaatt tctcttttca ttgtttttct tgtcgcatga tatgcctttt tgtgttattc
    24961 agttaaacta tagaaattct ttcctagaca gatcttgatc ccaaatttta cgtttttgag
    25021 catcgatata gtttaaaatg acattactca tatctaaaga gtttagattt tttaggacta
    25081 aaactgtcag ttgttctttt tcttctttct gttaaagtat tgtcgcgact tttcgtatac
    25141 gttaagatat gtcgtgaaaa aacaagtttt gtgacacaaa aaaacgaatg acttgaggaa
    25201 atcacctcaa tcattcgttt aaaatgctat atattcttta gtttaagata cggaaattaa
    25261 tgccatcgac cacactagta gaatgaacga catttacttg gccttttttt aatttcgtta
    25321 tgtttagcat ataaaaatat tatagagttt acttacaatg cttaaaacat atactgtata
    25381 atctgatcaa ttttagccat gtcttgcaat ggtaagtttt ctattttttt gagttttcgt
    25441 tccttaaaat caagagattt taattgtgta ataattactt gtccttttat atctagctct
    25501 tcaggtaatg agtaacgtgt cggtaaattc tttatagtgg aagtaattgg acatatgacc
    25561 gaaaacattg ttttacggtt aaattcataa cgagagacga ctagtcctgg tcgtcttttt
    25621 tgaatttctt ttcctacgga gggatcaaaa tcaatccata caatatcacc ttttttagga
    25681 atataaattc tttcttctga cactataaaa tttctctccc ttcaggagtt aaatcttccc
    25741 attcgtcttt ctcataatac tcggcctctt ccccaccact aaatggatct tcaatttttg
    25801 gaactaacgt aattgttcca tcatcagaat acacaacgat atattcttgg ttttctgaag
    25861 gtttctttcc gttatcagaa ggtaaagtta ccactacaga acttccttgt aatctagatt
    25921 ttgtaacaag cattatcatc actcccttaa taaaagtata ctatataaca ctaagtaacg
    25981 caaaattccc ctttgtaaac tatctagaaa attgttttgt ttaaagtata tcttattgga
    26041 tataaataga aataaattgt agccagttca ttttttcttt aactaaaaaa ataatccaag
    26101 aaacattgaa cctatggatc caaaagctac ccaaatacta tagctaaccc cccgctacct
    26161 tcaattttgc agataaaacg ctttgggaga aaatttcaaa gacaacaggc catcctatca
    26221 tgcccgatta taaacaaaaa gctggctatt ccttttgctc tgacaaattt caattgggaa
    26281 agttcacgaa actagcaggt gaagaagttt caactgttcg gatcaaagaa tgcccgcttc
    26341 aaatagaaac attggttcaa cgaatttcaa ctagacaaga ctttgctatt gtagaacgtg
    26401 agatcgtagc tatttttgta gaagaaggga ttttacatga tccaactcat atcaatgtgg
    26461 ataaatggca acctcttatc tataaattca gagaatatac aactgccaac cagtcgttaa
    26521 ctttgaattt tagattccaa gaattcaaag agtcataatg ataaacatcg ttaggtataa
    26581 ataaaaaaga ctcgcagcac gagtaaaaaa caaatagaag ctatacatta gaaaggtcga
    26641 ctgtgaccct atagatgcag tatatgcagc ttatgagcat ttcttctgtt ctctttgttt
    26701 ttgggatctg tgctgaagtc tttttcgttt tttgccgctc tttctttgaa aaatcgatta
    26761 tgttatacct tctccattac taattcaggc atctgctgag taatgatttt tcgcgcaaaa
    26821 gaaatatctg ttacccaagg ttcgatttgt tcttcagtca agacaagcgg cattcggtca
    26881 tggattggtg cgactgtgcg gttaggttca gtagtcatta tgattgattc tgccattttt
    26941 tcatcctgat ggctacgata aaaaccgcca atatacacta ttttttcctt atttgaaaac
    27001 ataaatttgt ctttttcttc attccactca ttgggaaaac acaacgattt tgcaaaaatg
    27061 gttgatgaaa ggtctttttt tcttctactg tctctgcacg ggcattaatc atcaattgtc
    27121 cttttttaaa tccggtaaat ccccacttca tgatttccgg agtgaggatg ttttcttcct
    27181 cttttcttaa cgtcacaaca agatttgacg gaaaaacttc tccagctgct aattctgctg
    27241 cctgcttcgg ttgtttcgtc tgggcttctc gataataatt ctgaaggagc tctgactcta
    27301 gatcaaaaaa ataacgacca cacatcctaa tccctcccaa tctttttttc tatcatacac
    27361 tgcaacaaga agttcgcacc aacaaaacgc tttcaatttt tgtagaacta aaaaagttgt
    27421 gacaagtgac aaactctcca gtgaatggta ttctcctgcc aactcctcgg tcacaagtca
    27481 caatattcaa caaacatgag aagctgcttt ttgaaattgt tccttgtgac tcggagtgaa
    27541 acggcaggct tacgacctct gggtaaacgg tgttcaaaag ccagtttctc ggtattaagc
    27601 caaatttatg caaaaatgta gaaagctatt ttcacaaaat ttttcttaat actcgaaact
    27661 aagcgacttt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat
    27721 aagcccaacc aaacgaaaaa tatgagcagc tatttttatt tggctgttct tattacttga
    27781 tgcagggcag ctttttcaca acctctccac taaacggtgt tcaatcagct aaccttcggt
    27841 attagctcaa aaaacggcaa aatatgagga actattttgc cgtttgtttc tctaatactc
    27901 aggtcaaagc gctgatttca caacctctaa tacacggtgt tccagaagta gcttcttcga
    27961 aaaataagcc gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt
    28021 cttgaagctg accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa
    28081 caatctttct ttgatcaatt gaaaattctg cctaagtagt gatagatcct gtgtgacttt
    28141 caacaataag atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc
    28201 ttcatcggac agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgaccca
    28261 ttgattgact aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat
    28321 aatcaaatta cctacaggac agccatgata agtgatctgt gtctcatgat cagcgaaaat
    28381 ccagtccaac atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc
    28441 gaacaattct gtctgccata cgtccatatg cgcatggatc accgctagac aaacttcttt
    28501 ttttgaagaa aagtaataat aaaattgacc ttttcctgta tcagaagctg ctagaatatc
    28561 tcggattgac gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat
    28621 cttttccttt gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca
    28681 gtaaattcat cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca
    28741 cagccctcac tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga
    28801 ggacaaaagc aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact
    28861 tgatctgcaa taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg gccaggagca
    28921 ccaattgcat ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg
    28981 gaatcgctac acaagtttcc gttcattcca ccaagaatta ctgtgtcgat tccatttttt
    29041 ctcaattgga gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgatg
    29101 atcgtatttt catccaaata aggtttcaat tcttcgataa aatcggctcc tgaaccttct
    29161 tccactgatt catattgact ttttctagca aacatctgct gctcaagcat catatgttct
    29221 cctgcaccgc caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag
    29281 agtttgtatc ctttttcttt tgcttgtttt accatttcaa tcatattttc gatcgtattg
    29341 tatttttcta agatatcttt tgtcaaacca aagccaccgc ctgctggttt caagaactcg
    29401 acttgcgggt cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca
    29461 ttcgttattt attttaatac atcatttaga gcttcactca ttgtcggatg agaatagatt
    29521 tgatctctca ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg
    29581 acttcatgag aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg
    29641 actaaaactt tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt
    29701 gtcatatact tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa
    29761 cctacattgg ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc
    29821 gttgttcgtt tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag
    29881 atataagtga actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct
    29941 gtacgaaggt attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt
    30001 tctaatccaa gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct
    30061 tggattgtta cttcttggcc atcttctgta aaggtgacgg cagctgttga ttcttggtct
    30121 gctacttgat ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct
    30181 aaaatcattt gcgcgatatc ttcatcttca cgtggaagaa attcagaatg ggcatcaaga
    30241 acgacaactt tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca
    30301 gccccgatga tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca
    30361 atcaagtagc gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta
    30421 ttgatgaaaa tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt
    30481 tgatggttag aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg
    30541 atcatatgat aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc
    30601 tctgtaaagt cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg
    30661 atgttgatac atgttccgcc atacatacgt gttgactttt caacgactaa aaccgattca
    30721 ccttttgaag ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata
    30781 ttttgatatt tttccatcat ttttccctcg cttctttttt acctaccgat tggtacaaaa
    30841 atatgataac cgataattgt ctattctcca aatcatctgc tttatttgtc aaaaaaaacc
    30901 agacaaaaag cggtcctttc acgtttttag tctggttcga tttcctttat tcttctaaac
    30961 aatcgttact tctacatcga tatttcctct agttgctttg gagtaagggc agaattcatg
    31021 cgcatcttct gcaatttttt gggcttcttc ttcgctgatg ccatcgatat gcacttctaa
    31081 tactacaccg atctgatagc cgccatcatc taaattataa agagagacac gtgcttttac
    31141 tgtggactct gctgtcattc ctgcttcttt gatcatatgt tgtaccgccc cattgaaaca
    31201 agaagcataa cctgctgcaa ataattgttc tggatttgtt ccttctgcat ggattcctgg
    31261 aggagtgatt ttcatatgca tcgagccatt tggtgcctcg acttctccat tgcgcccgcc
    31321 atggttgatc attgctgttt cgtatgcttt tttcattgta ctgctccttt cgattgacca
    31381 tttgctactt ggctataatt atagtgtatg acaagtaagg cgctttctac aaaaattctg
    31441 cttattcgaa taccagaatg ccgtcttcta ctatttttcc aaaaaacaaa aaaatactac
    31501 tcgtgaacaa cagcgtcata tttgttccaa aataaatagc aatcttttct acataatctt
    31561 ttatatgatt gattttaaga tacatatata ccagaaagtt gaccccataa accaatactg
    31621 ttaaaaaaat aaccatattc gttaccattt tttcctcctt ttgctggtct ccctaccagc
    31681 actcgattta accataccac tttttttgcc gtccaagcaa ctagcctttc aaaaagactg
    31741 gtttattctg ctgttaatga ttcaagatca gaaaaatgtc cgaataattt tgctaatttt
    31801 actaacgcca acttgttctt tccgaattca tcattttcta tctgtaatac tagtaacggc
    31861 tcatgtaagc ttaaacggat caaaaaccag ccgtttccgt atggctcttc tagatcatat
    31921 cgaatacctt cttcattttc cgggtcgaag ttcatccctt tttcttcttc caacagtcgc
    31981 ttcatttctt ctaatatctt gtttccttgt tcgcgtggtt catcgctgaa caattttaat
    32041 cggatttctt gtacttctac gggctgtttc aactctttga tttgttcatc taatgtgata
    32101 ccttttcttt ttaattctgg caaaagcatc aggatctttg cgatgacata tgcaccatca
    32161 tccagaaaat agttttcctt gaatgcagcg tgtccgcttg tttcgatggc tagctgtgta
    32221 tctttcccaa gacggttaag ttctaatgct ttattgatta catttcgata gccggaaata
    32281 taacgaactt ggatgcctcc tttttcttca atgaatcttt gtagatgaga agaagtaggg
    32341 gaattcgtca cgattcttgt tcctggatgc tcttttaata cgattgtact taatactgcg
    32401 atcaaattat ttcgattgat cactgttcca gaagcactga caactgcaga acgatccaca
    32461 tctgtatcga aaatgatccc aagatctgct tcatttgcta aaacagcctg cttgatactt
    32521 tccatcgctt ctttattatc aggatttggg atatgattag gaaatcggcc atctggttcc
    32581 aaaaattggg aacctgttga atccgcacct aagctattca atactttttc agcaaagaat
    32641 ccaccagcac catttccggc atcaacaatg attttccaac catttagtgg tttgctttct
    32701 agtgttccaa tccccttttt aatttttgtg actaaatctt gcgcataagg tgtcaaaagg
    32761 tctgcttttt ctacgcttcc agtttgttcg ctttttattt tttgctgctg tgataggata
    32821 aaagcaatat cttctttttc tgctcctcct tctgaggtaa agaattttat tccattataa
    32881 taatagggaa gatggctagc agtcagcata accgcagcat cgcacgagaa ctgttcaaat
    32941 tgagtggaca taaacatagc aggcgtagta gctaattcga aatcgatgac atgtatccct
    33001 tgttctttca gactttggat caacgcctct ttcagtgctg gtccgcttat cctactgtca
    33061 tgaccaatcc caatcgtcca ttttttattt ggatcggttg atttcttctt tttctttatc
    33121 cagtttgcta gtccccagcc gatctttttt accatgtctg tcgtcaagtt tacttcatat
    33181 ccttcaactg gtaatgcgat tcctcgaata tccgatccat tttgcagcgc tttcatatct
    33241 ttcatataaa agtcctcctc atttattccc tcattttttc cagcttttct gcaaatcgct
    33301 gtgcttcttc ttctgagcgg caaataataa tgaatgtatc tacaccggcc atcgttccga
    33361 caacttcagg gtaagccact tcatctagcc aattcgttac cacatcggca ccatttcgtt
    33421 cagtcaatac gataaccatg aactgaacag actggatacg caaaacctcg cgtctaattg
    33481 ctgtacgcaa acgttcttca tttaaagaaa cagatggctg gttaaataat gtatagcgta
    33541 ctattttgtt ttcattttga ctttttacta acttcatttc tcgaatgtct cgagaaatcg
    33601 ttgcttgagt cacatcggcg cctgcttcat gcagccgcgc aagcagctct tcctgtgtcc
    33661 caataggttg ttctgtaatg atctggcgga tcagtgcttg tcgctgtttc tttttcatat
    33721 tagacacctc tcaatgttga ttatagcaaa agataagtaa tatttcttca tattttggta
    33781 ttttttactt ttattttttg ttttcattca ggttgctaac ctttttctat tttaacacgc
    33841 aaaatcgtct tcattttttc aggtgctgat tttcttggat cgctgatgta aatctctttg
    33901 tgttctttag aagctctttc atagccttct tttgcgatga atgcttctaa tttctcaaac
    33961 gttgctggtt cttcggcata gggcccgacg tgtaagattt gggcacaaag accttcttcc
    34021 atctttttga atactacttg ttctttcaag tcttccggaa gtttgctaga acgctgaatg
    34081 gcttcttgtg ctatcgcttc tgtaacaaag tcaggctgtc ggatcatcaa ttgataagaa
    34141 aaatgttctt ttttcatcac tggttcatgc aaatactttt cttgcagtcc ccattgtcct
    34201 tccagtggat agacagtata catctgataa tcaggaatca gccaattttt tttaggcgac
    34261 atgcgtattg catagctgac tgcatataga caggctactc ttcgtttaaa gtcttcctga
    34321 ttcgggtcgc cgatccctct gatgctaaag aatgattttt taggaacctc tagtatttgc
    34381 gggctttttt tcatactata gctcttgtct ttacgccatt caattttttc catttttctt
    34441 cctccgcgaa attccattta gttatttatt atcatacctc tttttgagtg acttggctaa
    34501 tcgtgttgac actatttttc agtttgtgct agaataagtg aagtaaataa atcgtacaga
    34561 taacacgttt cggcgtgtcg agagagaggc ggtttctatt tttataatag aaatcactct
    34621 ctttttttac gaaatttttt agaggtgatg taaatgacaa aacaaaaaca gctgctttta
    34681 gtacctgcag taattgcaac agggatgatg tcttttgcgg gcgtattgat cgagacggcc
    34741 atgaatgtaa ctttcccaac tcttatcaga cagtttgatt taacgactgc acaagtccaa
    34801 tgggtaacaa cgatttatct tttgatgatt tcgatcattg ttccgctgtc tacttatttg
    34861 aatcgcaatt ttagtctcaa aaaactcttt ttagcttcaa atctgctttt cttggcaggt
    34921 ataatgatcg atttcttctc tcctaccttc atggtcctat tgtttggtcg attgctccaa
    34981 ggtgcagcga caggtatcgc tcttccgttg atgttccata ttatcttgac atttgccccc
    35041 ctcaatcgac gaggcgcgat gatgggtgtc ggtactttga caacggccat tgctccagca
    35101 attggcccca cttatggagg cattatgact tcacatttta catggaatca tatcttcctg
    35161 tttcttgtgc ccgttttgtt tctttctttg attatcggct ggtttgctat tcccgagatg
    35221 gcagtacaaa aaagtggtta tttggattgg ataagcgttt taggaatttg tcttttgttt
    35281 agtggaagtc taacattttt gagtacgttg ggaacagttt ccagctggat tgctttaatc
    35341 atcggcggta ttggctggtt ccttttttac tatcgaagta aaaaagtgga gcatccactg
    35401 atccgactgt ctattctttc aaataaaaca ttccgcttgt ttttgattgg cttcttagtt
    35461 tatcagtttt tattacttgg tgtatctttt gtcttgccga atttccttca gatcgttcaa
    35521 ggaagtagtc cttttgtcgc tggattagcg atgcttcccg gcgcagcggt tggtgctttg
    35581 ctttctcctt tttccgggaa aatgctggat caatatggtc cgaagaagcc aatttttgct
    35641 gggctgattc tttctttgat tggttggcta gcattattcc tactcatagg acacgcttca
    35701 gtgggtgtat tgattgcttg tcatgtgttt tatatgatcg gtatcggatt atcttacagc
    35761 aatatgatga ccaccggaat gaatgcactg aatgaagaac tacaaggaga cgggaacgca
    35821 atgttcaata ccttgcagca gttttctggc gctgtggcta cttcattagt agcggtcatt
    35881 atcaattacg tccagcatca tacttcccat aactatgaag tgtctactac attaggatca
    35941 aaagcagcat taggcgtctt gttgctgttg cttctcgtaa gctttgctcg attcgcctat
    36001 tatctgttct ttgctaaaaa agcgtagatt ccatatacgg caggtgttgc atctgccgtt
    36061 tttttgtgtg aaaatggttg tttgtaaaag gaggcttttt tatggaaaaa attgccatta
    36121 tcggtggcgg gatcattggt atgaccctag ccagttactt agatacatca aaattcaatg
    36181 ttgctttatt tgatgaaggg acaggacagg caactaaagc tagcgctggg attatctccc
    36241 cttggttgtc gaaacgcaga aacaaacaat ggtatcgtct ggctaaagac ggcgctgctt
    36301 ttttccctaa acttataaaa gatttccaac ttgatcaaac gatttacgca caatcaggga
    36361 cacttttgct tcgacctgaa aaagatttag ctgaattggc tgttcttgcc gagaaacgaa
    36421 aagaagaagc gccagaaatt ggaaacatcg aatggctttc acctgaacag acatctcaag
    36481 cacttccgtt attgaaacca gcagtttcac tgcgtatcag tggtggtggt cgtctggatg
    36541 gaaaagcata tttagaacat cttggtcagc gtttagcaca aaaacaaatg gagcagatcc
    36601 aggcaaaagt cactttgcat aagaagagcg attcttggct catcaaggga ccgtttggag
    36661 aatacacagc tgatcgtgta attttgacac ctggcccggc acttaagcct ttattacaag
    36721 aattaggcta tgctgcagat atacgtccgc aaaaagggca gctcttagca tttcagacat
    36781 cttataagat gagtcaagac tggcctgttg ctatgcttga cggagaagct gatttcattc
    36841 ctttcatgga tggaaagatc cttttaggtg ctacccatga aaacgatcaa ggctgggatt
    36901 tggctcctac tagcgaagct tataagggat tgactaagag tacagaacag ttcttgactg
    36961 atccagatca gataaaaaac tggccatacg agttccgtgt aggtacccgt gcttatacgt
    37021 cagatttttc cccatttttc ggcgtactgc cagatgatcc aagcttactg gctgctagcg
    37081 gtctaggctc ttctggcttg accacaggtc cttatatcgg ctatctatta gccaacttct
    37141 taaatactgg tcattggcct acggaagatt atcaaaagga catctccacc tatattacga
    37201 aaaatccatc atagaaaaac agctttttca agtaaggatc ccgagcgata ttgcgcatgg
    37261 attacttctt gaaaaagctg ttattttagt tcaatttctg aatcaaattc tccaaacttt
    37321 cttttgcttc atctggcaag agatcttttc ctatctgagc ttcaatgaat cgtaaacgaa
    37381 tatcaagtcg ttgtttcacc agatttttat aggacgtatc ctcaaaagaa acaggaaaat
    37441 ctggtatagg taaatagtgg atgtcttcaa atggaccaaa cgacttgaat tctgccgttt
    37501 gttgcacgat tctttcaacg attgacaatg tcgtttcagg tttgattttt ttatcatcga
    37561 aatatccagt attcaggaca tagcaggctg tttgctgttt caaaaacaac tctcgaaaag
    37621 cttgatagtc ttccctaaga ggatagacac ggaaaggatt agcaaatggt tcaatgacta
    37681 gctcatctag ctgtcttttt gtagtgatat tttccgcgtc tgatcgtttt gttgctaatg
    37741 ttgcaccaaa agacgctgct aaaactgggt cattgatctt gataattggc ggaagcgaat
    37801 catctttcat gatccaaaaa acagcatcga tcttttcgct aagatgatcg actcggtcgg
    37861 gtgtcgcata acgtgatttg actgtccgcc catttccgtt tcgtatatct cctgttacta
    37921 ggactttttc tcctttactt gtacatgtca cgcccacatt ctgacaagta aggaaagaag
    37981 aaatggccgg atcatcagac ggatagtctt gtgttttatc aaagtaagaa ggttccaagg
    38041 cagtagcaaa accatttttt cgagaaataa cgaaagcatc gtcatgcaag atcgaaacag
    38101 agtgaccttc cgtatgtttt gctaaggtaa tcgttgattt tccagaaccg gacaacccaa
    38161 atacagccat cgtataggtc tggtcattac tagcatattg tttcatccca ccgtggcagg
    38221 caataaagcc attgcgattt cccaatgccc aagcaagcgt caaagtcgct ttttttaatt
    38281 ctccaaagta acgtaatcct agcacagccg ctgtattatg gagagcatca aacaaaatga
    38341 gtccatttgg aaatgtttca tgtgtccatt cgggatcaca aaagatataa agatctccct
    38401 catcaaagga aacagacttt tgataagtct ctaagatctt cgaattcgct ggctgaaaat
    38461 tcagcaaata agaatacaaa ttgttctcaa atccttctgg aatcagcaaa tgactttgca
    38521 cagaaaattc ttcagatagg ccaacgatta cttttgtatg gtaaaactgg cgcttgcgac
    38581 tttgatacac agcttctctt aaaattttct cgtatttgct ttgttccttg tctaagtcct
    38641 caaagatccg ccgagcactt gctgttcttc ccacaatgct tccatcattg aatactagtg
    38701 tcctaacatc agctggtaaa tctagttctt cagcatgtga gattgttaaa tctgtgatga
    38761 tcgttcctgg actccctttt gctagttgat aagctgtctt cctatcaaaa acttcatgaa
    38821 cattattacc gtaaaatgtc gtttctacaa tcgatcgaat actggataac agtggatttc
    38881 cacttgtgat ttcgtttaat tcgagactct cttttgtact catggctcct cctcattccc
    38941 taaacaaaaa aacgttttct ttattataca ttattcgagt ttttatttgt actgctgcgc
    39001 tgtgggaagc aaacgagtta tttttcacac aaaaaaaccg agaacttgaa taaacaagtt
    39061 tctcggtttc atcattttcc ttttatcggc ttagtaccag ccgtttgcta accagaatgt
    39121 tttagcagca tcccatgaac cataacgaga tgttacatat tgttctgcta cacgttcttg
    39181 attggcagct gaatagtcgc cgtttaagta tgaagcatct aattgataac ggccgatgta
    39241 acgtccgtta gtagctgtgt atgaaccgcc tgattctttt tgtgcgatcc attcttttgc
    39301 agagcttgaa gttggcgctg ttgcagcagc tggggcagca ggagctactt caactgtttc
    39361 aacaggtgca acgtatgtat gttcttgcgt tgctgtttca gttgtagatg ctgtattttc
    39421 tgttgttttg ttttctgttg ttgctgaaga atcatttgaa gttgggattg ttaattgttc
    39481 accaacataa atgcggttga tgtttgcgat cgaatttttt tcagcaattg catcgatcat
    39541 tgagttgtct cctgcaaatt tttgtgagat cttagataat gaatcacctg attttactgt
    39601 ataaacttca tcagcgtgag catttgtagt tcctacaaac attgcagtag caccagcagc
    39661 aaaagttgta cctaaaacaa ttttcttaaa tgaattcata ttaaactcct ttttttctcc
    39721 gttttttatt ctttcgacgc tattaacttt atcatttaga aatatttcat aggtaaaaga
    39781 aacatgacat ttaatgacaa aataacgaat tatttaatat ttgtaacatt taaacaaata
    39841 tttttttgat acaaaaccat aaaagccttg ttgtataagc aaagtaatcg tttttctatg
    39901 tttttttatt tttgaatgaa aaacgcagat tctgtaacat tcactgcaat aatccataaa
    39961 aaaaagcaaa aaaatt
//
LOCUS       DADVXV010000017        36107 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.017, whole genome shotgun sequence.
ACCESSION   DADVXV010000017 DADVXV010000000
VERSION     DADVXV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.017"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..865)
                     /locus_tag="KB969_000834"
     CDS             complement(<1..865)
                     /locus_tag="KB969_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6868843.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIA"
     gene            1036..1404
                     /locus_tag="KB969_000835"
     CDS             1036..1404
                     /locus_tag="KB969_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBB6868844.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            1574..2005
                     /gene="mraZ"
                     /locus_tag="KB969_000836"
     CDS             1574..2005
                     /gene="mraZ"
                     /locus_tag="KB969_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBB6868845.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            2026..2985
                     /gene="rsmH"
                     /locus_tag="KB969_000837"
     CDS             2026..2985
                     /gene="rsmH"
                     /locus_tag="KB969_000837"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBB6868846.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            2990..3391
                     /gene="ftsL"
                     /locus_tag="KB969_000838"
     CDS             2990..3391
                     /gene="ftsL"
                     /locus_tag="KB969_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBB6868847.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            3392..5584
                     /locus_tag="KB969_000839"
     CDS             3392..5584
                     /locus_tag="KB969_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBB6868848.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            5610..6572
                     /locus_tag="KB969_000840"
     CDS             5610..6572
                     /locus_tag="KB969_000840"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBB6868849.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            6586..7947
                     /locus_tag="KB969_000841"
     CDS             6586..7947
                     /locus_tag="KB969_000841"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBB6868850.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            7973..9061
                     /gene="murG"
                     /locus_tag="KB969_000842"
     CDS             7973..9061
                     /gene="murG"
                     /locus_tag="KB969_000842"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBB6868851.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            9076..10296
                     /locus_tag="KB969_000843"
     CDS             9076..10296
                     /locus_tag="KB969_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBB6868852.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            10452..11777
                     /gene="ftsA"
                     /locus_tag="KB969_000844"
     CDS             10452..11777
                     /gene="ftsA"
                     /locus_tag="KB969_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBB6868853.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            11800..13041
                     /gene="ftsZ"
                     /locus_tag="KB969_000845"
     CDS             11800..13041
                     /gene="ftsZ"
                     /locus_tag="KB969_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBB6868854.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            13058..13735
                     /locus_tag="KB969_000846"
     CDS             13058..13735
                     /locus_tag="KB969_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBB6868855.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            13749..14348
                     /locus_tag="KB969_000847"
     CDS             13749..14348
                     /locus_tag="KB969_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBB6868856.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            14363..14650
                     /locus_tag="KB969_000848"
     CDS             14363..14650
                     /locus_tag="KB969_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBB6868857.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            14699..15481
                     /locus_tag="KB969_000849"
     CDS             14699..15481
                     /locus_tag="KB969_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBB6868858.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            15502..16209
                     /locus_tag="KB969_000850"
     CDS             15502..16209
                     /locus_tag="KB969_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBB6868859.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            16471..19269
                     /gene="ileS"
                     /locus_tag="KB969_000851"
     CDS             16471..19269
                     /gene="ileS"
                     /locus_tag="KB969_000851"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBB6868860.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(19318..20844)
                     /locus_tag="KB969_000852"
     CDS             complement(19318..20844)
                     /locus_tag="KB969_000852"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBB6868861.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(20859..21506)
                     /locus_tag="KB969_000853"
     CDS             complement(20859..21506)
                     /locus_tag="KB969_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBB6868862.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(21690..22019)
                     /locus_tag="KB969_000854"
     CDS             complement(21690..22019)
                     /locus_tag="KB969_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBB6868863.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            22196..22924
                     /gene="sfsA"
                     /locus_tag="KB969_000855"
     CDS             22196..22924
                     /gene="sfsA"
                     /locus_tag="KB969_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBB6868864.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            22940..23953
                     /locus_tag="KB969_000856"
     CDS             22940..23953
                     /locus_tag="KB969_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6868865.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            23953..25230
                     /locus_tag="KB969_000857"
     CDS             23953..25230
                     /locus_tag="KB969_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6868866.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            25293..27995
                     /locus_tag="KB969_000858"
     CDS             25293..27995
                     /locus_tag="KB969_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6868867.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            28147..28464
                     /locus_tag="KB969_000859"
     CDS             28147..28464
                     /locus_tag="KB969_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6868868.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            28494..28814
                     /locus_tag="KB969_000860"
     CDS             28494..28814
                     /locus_tag="KB969_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6868869.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            28922..30382
                     /locus_tag="KB969_000861"
     CDS             28922..30382
                     /locus_tag="KB969_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6868870.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            30450..30671
                     /locus_tag="KB969_000862"
     CDS             30450..30671
                     /locus_tag="KB969_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868871.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            30702..30884
                     /locus_tag="KB969_000863"
     CDS             30702..30884
                     /locus_tag="KB969_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBB6868872.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            30884..31297
                     /locus_tag="KB969_000864"
     CDS             30884..31297
                     /locus_tag="KB969_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBB6868873.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            31420..32601
                     /locus_tag="KB969_000865"
     CDS             31420..32601
                     /locus_tag="KB969_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868874.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(32672..32836)
                     /locus_tag="KB969_000866"
     CDS             complement(32672..32836)
                     /locus_tag="KB969_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868875.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            32990..33063
                     /locus_tag="KB969_000867"
     tRNA            32990..33063
                     /locus_tag="KB969_000867"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33024..33026,aa:Arg,seq:cct)
     gene            complement(33132..34271)
                     /locus_tag="KB969_000868"
     CDS             complement(33132..34271)
                     /locus_tag="KB969_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6868876.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(34570..35205)
                     /locus_tag="KB969_000869"
     CDS             complement(34570..35205)
                     /locus_tag="KB969_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868877.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(35318..35953)
                     /locus_tag="KB969_000870"
     CDS             complement(35318..35953)
                     /locus_tag="KB969_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBB6868878.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(35987..>36107)
                     /locus_tag="KB969_000871"
     CDS             complement(35987..>36107)
                     /locus_tag="KB969_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBB6868879.1"
                     /translation="SKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
BASE COUNT        11924 a         6152 c         7474 g        10557 t
ORIGIN      
        1 cagcaatagg taacttaatg ttcattccat agatactgcc gacgattgtc ggtatagtta
       61 aaataatcgt taaagaagtt aaaattttca taatattatt cagattattc gatacgattg
      121 ctgaaaaagt ctgattcatt tgttctacta gttttaattg aatgcgagaa gtagtcattg
      181 cctgctctgt ttccaccaat acatcacgta aatgattttt caaagcatga ttttcttgga
      241 aaagtttatt ttgcgctagt tctttcaatg catctaaatt agcagaagtc gcttctctga
      301 aataaacgag gcttttttgg atatccatga tttgataaag ttgtttgttt tcagtggata
      361 cttgaagttt ggcttccaaa gtatcgcatt gagattgaag cgtagctaaa taactgttgt
      421 aagagagtgt gacctgccaa atgaattgaa agaagatatt gagattaggc gaaatatcac
      481 tttttggaaa ggtctggcta aagactttct ttaaaaacag tggttcatga ttcgtaattg
      541 tgataagctt ctttttgggc gtcaaaataa tagagagcgg gtatgtatcc acttgaaaat
      601 aaccgctagg acttgtttta gcaaaaggat attgtaacaa taataacgct ggctttgtca
      661 actttgattg attgaattct tctgtacggg aattttctgc atcgtccaat atggaagtga
      721 tgtaatctga cggaatttca aattgatgtg tcagctgatg aatctcttct tgattaggac
      781 gttctacaca ataccagatc gtttggtcag tttcctttcc ggtattacgc agtttctcat
      841 tatctaatgt aaaatatttg atcatgattt tcctcctgtt gcctgtttct tttattataa
      901 cggataggga attggaatac atggaatgtg tttgtaagat atagaatata actgcataaa
      961 tttaaataaa atgaaacagt tgtgtaaagt atatacagta tacttgaagc aacgataaaa
     1021 aaggagttta cgttcatggg cacattcaca ccacttatct tgttttggta tatttacccg
     1081 gtaatcgttt tgtttggttg ccaatttctt gtaaaattat tttcgttaaa tcgtcgtttt
     1141 aaaataaaag cccctgattt ggcgattcct tttttgtggg gcggtatgca tgcattgtct
     1201 agaaatacag ggacaatttc tatcttaccg tttttcttta tttctgtttt gctaatggga
     1261 atttgtattg ctgttttcca agcatattat tatgaagaaa ttatttatcc gcgttatttc
     1321 aagatgactt ggcgtttggt ttttctgttg acaatcgtct tgtacgctgt cttgatcatt
     1381 gtgaacatac tttcttacct atgaaaaaaa tagaaaagct gtaaaaagtc ttttaaaagg
     1441 ctttttgcag cttgattttt aaaaaaatgt ttatgaataa aaaaagttgt tcccggattt
     1501 cccagaaaag gtggtagaaa gtgggggatt gtggtagact aattttagtt agtggaggaa
     1561 tggggggctt tcaatgttga tgggtgaatt ccaacataat attgatgcaa aaggacgttt
     1621 aatcgtgccc tcaaaacttc gtgaagaact tggcgaaaag tttgttctga cacgcggatt
     1681 ggatggctgt cttttcggct atccgatgag cgaatgggaa aatctggaag ctaaactgaa
     1741 cgaaatgccg ttggctaaaa aagacgcacg tacttttgtg cgattcttct attcggctgc
     1801 cactgaatgc gaacttgata aacaaggacg aatcaatata cccagcacgt taagaaatta
     1861 tgcagctttg acaaaaggtt gcgtagtcat cggtgtatct aaccgaattg aaatttggga
     1921 tgagacacga tggcaagatt tttctgcagc agcagaagag aactttgacg aaattgctga
     1981 aagtatgatt gatttcggac tataagaata ggaagaggct gactaatgac tgaaacattt
     2041 caacactata cagtcatgtt gaaagaaacg gtagatggat tgaacatcaa accggatggc
     2101 gtttatgtag actgtacact cggcggtgcc ggacatagtg aatatttatt aagccaacta
     2161 agttctaaag ggcatctgta tgcgtttgac caagatcaaa aagcaatcga tcacgccaag
     2221 ctgcgtttag cttcttatgt cgaacaaggt atggtcacat ttatcaaagc gaacttcaga
     2281 gaattagaag aacgcttgag tgagcatgta gataaggtag acggcatttt gtatgatcta
     2341 ggggtttcct ctcctcagct agatgaagca gaacgtggat ttagttatca tcaagatgca
     2401 ccgttggata tgcgcatgga tcagtcagct cctttatccg cttatcacgt aattaatgaa
     2461 tattcctacc atgaattagt aaagattttc ttccgctatg gcgaggagaa attttccaaa
     2521 caaattgctc gtgaaatcga acgagtacga aaaacaaaac caatccaaac aactggtgag
     2581 cttgtcgaaa tcattaaaca agtcatccca gctcccgcaa gaagaaaagg cgggcatcct
     2641 gcaaaaagaa tttttcaagc tgtgcggatt gcagtaaatg acgaactcgg tgccgaagag
     2701 gcctctttag aacaggcaat ccggttattg aaagtcaatg gaagaatcag cgtaatcaca
     2761 ttccattcat tggaagacag aattgtcaaa agtatgttta aagaatatag tacggtacaa
     2821 gatctaccac cgggacttcc tgtcatacct gacgaattcc aaccagaact gaaagtcatt
     2881 actcgtaaac caatccttcc ttcagaggaa gagctaacag aaaacaatcg atcacgcagt
     2941 gcaaagttac gtattgcaga aaaaataaga atgaaagagg agtagaatga tggcagaatt
     3001 aaagaaaatg caagattacg aatatgattt acctgaattg gtggatcagc cggaacaaca
     3061 aatgcctgat tcttcttcga atcaagaaat cattcttcca caatcaccgg caaaacgatt
     3121 aaagcagatt tctgctttgg aaaaaattgc tgtggcaagc gtggcgattg ctattgttgc
     3181 tttatgtgtt ttaacagtta tgctgcgcac aaatatcagc ggagctgaaa aagaaatcac
     3241 gtcaatacaa acagaaatca atgataaaaa gcaagaaaaa acgagtttag aacaagaaaa
     3301 aaacgaactt tctcgtactg aacggattaa acaaatcgca gaagaaaaag gattgtctat
     3361 taatgacgac aatttaagga aagtgaagta aatgagtctt aaaaataaaa ttcggcggtt
     3421 tatggaaaag aaaaatctaa atccgatgaa caatcgcaaa aaagtaggta tcattttatt
     3481 tgctacgagt attggattgt tctttttatt tgccgtccgt ttctcgtata tcgttattgg
     3541 aggtcatgtt gctggtacct cattagctga aaaaacaaaa cagttgtacc aaggaagtga
     3601 agtagtaaaa gcaaaaagag gaacgattta tgatcgtaac ggtgtggcgc tcgcagaaga
     3661 tgcctcctct tattcaatta aagcgatact ctcaaaaaca tatacctctg gggataaaaa
     3721 actgtatgtt gaagaaaaga attttgataa aatagcagaa atcctgcata agaatctttc
     3781 tatagacaaa aaagatgcac tgaatatttt agaggacggc gcaaaaaaag agctgtatca
     3841 agttgaattt ggtagctatg ggaaaaatat ctcccaagaa accaagcaaa acatcgaagc
     3901 ggacatgaaa aaagaaggtg tcgctggtct ttattttgtc gaccatcagg ctcggatgta
     3961 tccaaatggc gtcttttctt ctcattttat tggatacgca gttccagaca aagatgagaa
     4021 tggcttagtt ggtaaactag gtttggagtc tgcttacaat gatatcttga gcggtaaaga
     4081 tggtaagatt atttatcaaa aagataattt tcaaaatcct ctgccaggta cagtggcaga
     4141 agaagaaaaa gctgtcgacg gacaagatat ctacacgact ttagacagca gactacaaag
     4201 ttatttagaa acactgatgg atcaagtaaa tgaagaatat cagccagaag aattgacagc
     4261 agtcctgatg aaagcaaaaa ccggagaaat cttggcaatg ggacaacgac ctactttcaa
     4321 tcctgaaaca atggaaggat tgactggaaa agatgctatc tggcgtaatt tcttggtaca
     4381 agatagttat gaaccaggat caaccatgaa agttttcact actgcagctg ctatcgaaga
     4441 aggagaattc aacgagaatg aaaccttcca atctggaaaa atccaagtag aagatgctac
     4501 gatcaatgac catgactttg gtgaaaaagg tgtgctgacc atgcgtcaag ctctttcatg
     4561 gtcaagtaac gtcgggatgg tcatactgga acagcgatta ggcggacgat ggtataacta
     4621 tttacaaaaa ctgggatttg gacaaagtac tcattctgga ttagatgatg aagtaaacgg
     4681 tgctttacct acattaaata ttgtcgaccg agcaatgagt gcttatggac aagcggtagg
     4741 tgtgacgaat ttccaaatga tgaaagcttt cacttctatt gcgaataacg gtacaatgat
     4801 tcaacctcga tatatcagca aagtggtgga tccccaaact ggagaagagc gaacaactca
     4861 aacagaagtt ctagggcaac ctttttcaaa agaaacaaca gaaaaagtcc gtgaatatat
     4921 gagagatgtt gtcgaaagcg aaaactacgg tagtgcttat ggtgtatata gtgtacctgg
     4981 atacaatgta tcggcaaaaa acggaacagc ccaaatcgct tctgatacag ggggatatca
     5041 aacaggagat acagcctacc tgtattcgat tgtggagatg gttccttctg aagatccaga
     5101 ctatgtcttg tatctaacaa tgaaacaccc taagacatat gatcgaatgg cattggctaa
     5161 aatcgcaaat ccattgatga aacgggcaat ggattttaaa gaaactgaag aagattcaga
     5221 tacagaaaca aaaacagaaa aagtatccgt agccgattat cgtaatcttg aagcggacgt
     5281 tgcagcagct gatgctcaaa aaagtggact gcaacctgta gtgatcggta atggtaaaaa
     5341 agtacaaaaa caatctactg ccaacggtga tcagttgatc tctggagaaa aactgatcct
     5401 atatactggt ggtgataagc tgatgcctga cgtaacagga tggtcaaaag cagatatcat
     5461 gaagctgggg aaaatcctcg gtattgaagt tagttttgat ggagatggtt attgtgtcaa
     5521 acaagaactt gctccatatg aaaaaatcac tgaagacaaa cttagtttta ctttagaaga
     5581 ataagaagag aaataggaga gaaaagagca tggaatggac acaagcattg attcccattg
     5641 tcagcagttg tgcaatgaca attgccgcaa tgccgctatt tattggttat tttcaaatga
     5701 aaaagcaagg tcaggcgatt cgtgaggagg gaccaaagtg gcacaatagc aaagccggaa
     5761 ctcctacaat gggcggctta gtgtttctga tcggctctat tttgacagga atttgggttg
     5821 gagcttggca aaaacagcta actcctactc ttttcatctt gctttttgta ttagcgttat
     5881 acggagtaat cggctttctt gatgatttta taaaaatatt caagaaaaga aacatgggac
     5941 tgaactcgaa gcagaaattg attggacaga ttctaggggg aatcatcttt tatcttgttt
     6001 accgttctga aggttatcca ggtgtattga atttcttcgg actagatcta cctttaggaa
     6061 tcatttatgg tattttcgct ctcttctggc ttgttggatt ttcaaatgca gtaaatctga
     6121 cagatggcat cgatggatta gttgctggct taggaagtat ctcttttgca gcttacggtc
     6181 taattgcttg gcatcagcat cagtatgatg tattaatcat ttgcttaagt gttttaggag
     6241 gtttactggg tttcttcgtc tacaacagaa aacctgccaa gatttttatg ggagatgtcg
     6301 gttcattagc gttgggcgga cttttagcgg caatttctat aatgctaaac caagaatgga
     6361 cattgctttt gattggtttg atctatgtta tggaaacagc aagtgtgatg cttcaagtta
     6421 cttcctttaa gcttacagga aaacgaattt ttaaaatgtc tccaattcat catcactttg
     6481 aaatgtgcgg atggtcggag tggaagattg atacagtttt ttggttgatc agcattgtga
     6541 cttcgttgat cacattatgg atcgtttggt aggagatgac gggaaatgaa aaaaatatca
     6601 acatatgaaa ataagaaagt gcttgtctta ggactcgcaa aaagcggagt aagtgcggcc
     6661 aaattattac atgaattggg cgcacttgtc accgttaatg atggaaaacc ttttgacgaa
     6721 aatccggaag cacaagagct gctttcttta gggataaaag taataacagg tagtcatcca
     6781 atcgaattgt tggatgaaga attttcattg atggtcaaaa atccagggat tccctacagt
     6841 catcctttag tagcaaaagc ccaagaaatg ggtattccgg taattacgga agttgagcta
     6901 gcttacgaag tagcggaatg cccaattatt gggattacag gaacgaacgg aaaaacaacg
     6961 acaacaacga tgacaggact actactgaat gcaggagcag atcaaggaat tgcacgttta
     7021 gcgggtaata ttgggtatcc agcaagtggt gtagcgcaag aagcaaaatc agaagataaa
     7081 attgtgatgg aattgtctag cttccaactc atgggaatca cagatttccg ccctcatata
     7141 gcggtgatta ccaatatcta tgaagcacat attgattatc atggtacaag aaaagaatat
     7201 gtcaaagcta aatggaacct tcaaaaaaac atgacagaaa aagattatct gatccttaac
     7261 tggaatcagt cagaactaca agaattagcg caaagaacaa aagcacgcgt actgcctttc
     7321 tcgacaaaag aagtgttgga agacggtgtg tatgctgacg attactcaat atactataaa
     7381 aaagaaaaaa taatggaaat atctgaactt ggcgtaccag gtaagcataa tgtagaaaat
     7441 gcactagctg ctatttctgt agcaaaattg tatggtatat caaatgaagc tatacgagaa
     7501 acgttgcatt ttttccatgg cgtaccacat cgtacgcaat atgtaggaga aatccaaggc
     7561 agaaaatttt ataatgattc aaaagcaacc aatattttag cgactaaaat ggctctaagt
     7621 ggatttgaaa cgtctaaggt cgtgttattg gctggcggat tagacagagg aaatacattt
     7681 gatgaattaa ttccttcatt aaaaggaatc aaagcaatgg tcgtatttgg ccaaacaaaa
     7741 gaaaagttga tggatgctgg aaaaaaagca ggcatcgaga caatagtaac agccgattct
     7801 gtagaacaag cagttccttt agcattagaa aacagtacag atggtgatgt agttttatta
     7861 tcaccagcga atgccagctg ggatcaatac ccaaattttg aaactagagg aaacagattc
     7921 atggaagctg tgaaccgatt aaaatagaaa aagtagaagc gagcgataaa aaatgaaaat
     7981 tttggttaca ggcggaggaa cagggggaca tatttatcca gctcttgcct ttgtcaatta
     8041 tgtaaagact caagaaccga atgctgaatt catgtatgtg ggagcaaaac gaggtctaga
     8101 aaacaaaatc gtccctgata caggaatgcc tttccatacc ttggagattc aaggatttaa
     8161 acgaaaaatt tccatgcata acatcaagac ggtccgattg tttcttaaga gtatccgtca
     8221 agcaaaaaaa atcctcagtg attttcaacc agatatcgtt atcggtactg gaggatatgt
     8281 ttccggagcg gtagtgtacg ctgcagccaa aatgggtatt ccaacagtta tccatgaaca
     8341 aaacagtgta ccaggtgtta ccaataaatt tttaagccga tatgtggatc ggatcgctct
     8401 ttcatttaaa gatgcggctt ccttttttcc tgaaaacaaa gcagttcttg taggtaatcc
     8461 tcgagcacaa gaagtagcag atactaaaaa atcagatatt ttgaaaacat ttgatttgga
     8521 tccagaaaag aaaacagtct tgatttttgg cggtagtcaa ggagcactta aaatcaatca
     8581 agcagtatca gtttttttaa gtgaatatat tccttcttct taccaagttt tgtatgcttc
     8641 aggagataga tattatgaag agatcctaaa taaaataaat cctgaaatac aaaatattag
     8701 tgtccagcct tatatcaaaa atatggcaga ggtcatggct tccagtgatc tgctggtggg
     8761 gcgtgctggt gcaacttcga tcgcagaatt cacagctctg gggttaccgg cagtgttggt
     8821 tcccagccca tatgttacga atgatcatca gactaaaaat gcaatgagtc ttgttcacgc
     8881 aggagcagca aaaatgattg cagataatga actaacaggt gaatcactaa gtcagacagt
     8941 caacgaaatc atgggtgatg aagaattgca aaagcaaatg tgccgagctt ctaaagaaca
     9001 aggaatccct gatgcttcaa aacgtcttta tgacttagta aaacaaataa tcaaaaaata
     9061 aaggcggtgg tcttagtgag taagaaaaaa gaaccaaaaa aattgtctca tccgtcttct
     9121 gatgaaaaca atttgactcc ttggcaaaag gctaaccgaa aatatctggc agaacaagag
     9181 atgaaaaacc aagagccaaa aaaagaagac ataacattag atacacccct ttcagattct
     9241 gaagaagaaa aaacggttca agaggaacag caagaagaaa gccagtccga gaaaaaaatc
     9301 gaattttttg aagagatcaa gcaaaagaaa aacggtggac catataacgg ttcttttttg
     9361 aaccggctgc ccaatttaaa aagtcaacgg cacaaagtac tatttcgtcg gttagctttg
     9421 atcatcactg tattgggtat accgctgatt tttttgatct attatgtttc tccttatagc
     9481 aaattacaag cagttgcagt atcaggcaat aagacagtca acagccaaga aatcatctct
     9541 gatacaaaat tgtcattagg agaaaatgtt tggggacagt attttcatcg atctacttat
     9601 atcgatcgcc ttaaaaaagc acagccaaga atcgaaacag caaatataca tttcaaaggg
     9661 atgaatgaat tcgatttgga tgtaacagaa tataaagaga ttgctttgat cgcaaaaaac
     9721 aatcaatact acccagtgat tgaaaatgga acagtattag atgaaaaagt agcaaatcct
     9781 acaaaaaatc tccctatctt ggaagagttc aaagactctg caaaaatcaa agaattaaca
     9841 aagcaataca atcagttatc atcagaatta caaaaagcaa tttctgaaat caagtacacg
     9901 ccaagagcaa gcaataaaaa tctgatccaa ttgaatatga atgacggcaa tcaagttatt
     9961 gtaaatatca ataatcttgc gaaccaaatg aaatattatt cgcaagtagc caaagatatg
    10021 gatgaaaaag gtgtgatcga catggaagtt ggtatcttct cgcatcctta cggtagcact
    10081 caagaaacgg aagaatcggg ccaatcggaa gaaacaactg aaagtgaaga aaatgcggat
    10141 caaacaaacg aatcaagtga agaggcagaa acgcaaaaag cacaaacacc tggatcgtct
    10201 agcacaaacg gatcatctga ttcaaatgat tcaagtgaaa caagtcaaat agaagataat
    10261 ccaagtacaa ctccgtcaag tttaaatgaa aattgataaa acaactttaa aaagtaagaa
    10321 tgtactttct aaaaaccagt aatttatggt agaattggaa gcagtgaata tatctattaa
    10381 taagtatatt ttaaaacgga cgctagttgt tcgcttgtat atggaatagt aagtaggagg
    10441 gaatcccatt catggcaaaa acaggaatgt atgtaggcct tgatattgga acgacatctg
    10501 ttaaagttgt cgtggctgaa tatatcgaca gccaaatgaa tattattgga gtaggaaacg
    10561 caaaatcaga agggattaac cgaggcatta tcgttgatat cgataaaacg gtccaagcga
    10621 tacaacgagc agtacgacaa gcagaagaaa aagcaggtat ccagatcaaa ggcgtaagtg
    10681 tcggtttgcc agcaaacatg cttgaagtag aaaattgcca gggaatgatt gcagttaacg
    10741 gagattcaaa ggaaatcacc gatgaagatg tcagaaatgt ggcttcagct gcccttgttc
    10801 gttcaatacc tcctgaacgt caaatcgtgt caatattgcc acaagatttt actgtcgatg
    10861 ggttcgaggg aatcaaagat cctcgtggaa tgatcggcgt aagattagaa atgtacggtc
    10921 tgttgtttac aggacctaaa acgatcatcc ataacatacg taaatgcgtg gaaaatgccg
    10981 gattaatcgt caacgaaatg gtgattactc ctttagcgct gactgaatca attctttctg
    11041 acggagaaaa agattttggt acgatcgtca ttgatatggg tggcggccaa acaacaacgg
    11101 ctgttatgca tgataagcaa ttgaagttta ccaatcttga ccaagaaggt ggcgaatttg
    11161 tcactaaaga tatctctatt gtattaaata cgtcatttaa caatgcagaa gcgttgaaaa
    11221 taaactacgg ggatgcatac ccagaacgga catcaccaga tgaagaattt ccagtagatg
    11281 tgattggtca gtcagaacca gtgaaagtcg atgaacgcta cttgtcagaa attatttcag
    11341 ctcgaatgga acagattttc aacaaagcaa aagatgcatt ggaccaaatc gaagcattag
    11401 agttgccagg tggcgtcgta ttgacaggcg gagctgctag tcttcctggt gttgtggact
    11461 tggcacaaga aatcttcggc gtaaatgtaa aattgtatgt tccaaatcac atggggctga
    11521 gaaacccggt atttacaaat gtaataagta tcgtggatta ttcagcaaac ttgagtgaag
    11581 tgtatcaatt ggcaaaaatt gctgttacgg gtgaaacctc agcagctcgt caaatggtag
    11641 ttgaacaaga aacaacaaac acatatgaga gctatgaagc acctgaagaa acaatctacg
    11701 atgagccgga accaaaagag tccggagaaa atgtaaaaaa taaaatcaag ggtttcttta
    11761 caaatatttt tgattaattc atcctgggag gaataagata tggaattctc aattgataat
    11821 aatatcaatg acggcgcagt aatcaaagtc atcggagtcg gtggtggcgg tggaaatgct
    11881 gtaaaccgaa tgattgaaga aaacgttaaa ggtgttgaat tcattacagc caacacagac
    11941 gtgcaagcat taaaaaattc aaaagctgaa acagttatcc aattaggccc caaatatact
    12001 cgtggtttag gtgctggttc tcagccagaa gttggacaaa aagcggcaga agaaagtgaa
    12061 caatccttac gcgaagcttt agacggtgca gatatgattt tcatcactgc aggaatgggt
    12121 ggaggaaccg gtacaggtgc tgcaccaatc gttgcaggta tcgcgaaaga attgggcgca
    12181 ttgactgttg gtgtcgtgac acgtccattc acttttgaag gaccgaaacg tggccgtttt
    12241 gctgcagaag gtatcgctcg tttgaaagaa aatgtggata cattattaat tatctcaaat
    12301 aaccgtttat tagaagttgt agataaaaag acaccgatgc ttgaagcttt ccgtgaagca
    12361 gataatgttt tacgacaagg tgtacaaggt atctctgatt tgatcacagc gccaggttac
    12421 gttaaccttg actttgctga cgtgaaaaca gtgatggaaa accaaggtac agcattgatg
    12481 gggatcggtg tggctagtgg agaagatcgc gtagtagaag caacgaaaaa agcaatctcc
    12541 tctccattgc ttgaaacatc tattgatgga gctgaacaag tacttcttaa catcacaggc
    12601 ggtttggata tgacattgtt cgaagcacaa gatgcttcag atatcgtagc aaatgcagca
    12661 actggcgatg taaatatcat tctaggtaca tctatcaatg aagaaatggg cgatgaaatc
    12721 cgtgtgacgg tcatcgcaac aggtatcgat gaatcaaaaa aggaacgcaa gtctagccga
    12781 ccagctagac aagcacaaat gcaatcacct gctcaaaaga ctgtattaga tatggatcaa
    12841 gctaaaccaa cttcttcaga agaagaaaac agttttggcg attgggatat cagacgtgaa
    12901 caaaatgttc gtcctagagt tgatgattcc aattttgaca atatcgaaaa aaaagaattt
    12961 gatacattca accgcgaaga aacaaaatct catggcgatg atgaattaaa tacgccaccg
    13021 tttttccgtc gtaaaaaata aaggagagga agagcacatg attgctgaca acttgcagaa
    13081 aatcaagcaa gaaattcagg attcgtgtgc tcttgttcat cgtgatccga aagaagttac
    13141 attagtagct gtaacaaaat ctgttgaatc cgctcaagct gaagaattgg ttagagctgg
    13201 cgttatgaat tgtgcagaaa accgagtaga taaattatta gaaaagaaac aagatttatt
    13261 tgattttcct gaaataaagt ggcatttaat tggtaattta cagcgcagaa aggtaaaatt
    13321 gattgtaaat gaaattgatt actttcatgc gttggacagt ttaagattag cagaagaaat
    13381 ccagaagcgg ttagagaaag aattatcctg ttttattgaa gtaaatgttt ctggtgagga
    13441 atcaaaacat ggaatttcac cagatgagct tttaccgttt gtggaatctt tagctgcctg
    13501 cacaaaaatc aaggttgttg ggttgatgac tatggcgcct aaagaagctt ctgatgagca
    13561 aatccataaa gtgtttggta cgctgaaaga attgcgtgat cttgttcaag caaaaggtta
    13621 tgcccatgca ccatgtagtg aattaagtat ggggatgagt caagactttc aaattgcgat
    13681 tgaagaaggt gcaacattta tccgtgtagg aacagcgcta ttcaaagacg aataaaggag
    13741 gaacaaaaat gccgctttta aacagaggag caattgctaa ttttttcgga ttagctgatg
    13801 aggaagagta cgaataccaa gattatcctg aaacaacaaa aaaggctgta cagccaacta
    13861 aaaaaaatac aacacagaat caatcaactc attctgtatc tgctgcgaat actcatgaaa
    13921 aacaaaaaac ggcgacttca cgtcctgtaa cgcatgaaag tattcagccg gctgaaaaga
    13981 aaaaagtaat tgaactacat caatcaccta caaaaactgt agcgaaagaa agaacagctt
    14041 caagaacctc tacacaacct aaagcaaatc ttgctggaaa aatcactgta atggaaccaa
    14101 gagcttattc tgaagctatg gcgattgcta aacgaatcat tgctggagaa gcaaccttag
    14161 tgaattttca tttagtagaa gaaaaacaag cgagaagaat cgttgatttt ctaacaggaa
    14221 cagtttatgc actagatgga gatatcaaac gtgttggaga tgagattttt ctttgtacac
    14281 cgactgggat ggagattgac agttcaaccg ctcaatcttt tgcagatgcg aatttgtttg
    14341 atctgtaaga ggaggaacta cgatttatac tattgcacta ttacttcatt tacttcaacg
    14401 ggcagcctat ttctatagca ttatcttgat ggtatatgca ttgctctctt ggtttccagg
    14461 cgggtatcaa tcagggctag gacgattatt agctaagatc tgcgaaccgt atatcagttt
    14521 gttcgatcgt ctgcctttga ggattggacc cttggatttc acaattttag gggcaatcct
    14581 gatcttgaac ttagccgtac aaggtttagc acagatcgtt atatggataa ctgtccattt
    14641 agtttattga ttgaagcaac aaaatcttta ttctcagaat agataggagg ggaaaatttt
    14701 ggatgcaaat gtataccagc actttcgggc agatgaacgt acatttatcg attcggtagg
    14761 cgattggatt gaacaggttc aaggacaata tgcaccctat ctgaccgaat ttcttgaccc
    14821 aagacaatcc tatattttag aaacactgat tcgacaaagc agtgatttgc gtttcatgtt
    14881 ttatggcgga tatgaacagg cagaaagaaa aagatgtttg attttccccg attattacga
    14941 acctgtagag gaagattttg aaacagcatt gtatgaaatc cattatccta gcaaatttgc
    15001 cagcctaagt catgggaaaa tccttggaac tttagtggga acggggatca aacgctctta
    15061 ctttggcgat atcatctcgg acggtgatcg ctggcaagta tttattgcaa atgaggtgga
    15121 tcattttgtt gctgcacaag taacaaagat tggaaaggtt gctgtacgct tggaaccaat
    15181 caaatacaca gaaatgatta tgccgaaaga tagctggaca caagaaagag gaacagttag
    15241 ttccatgcga ctagacagtg tgatctctga gatttataat atttccagac agcggtccaa
    15301 gcagctgatc gaagctggta aagtaaaagt gaactggaca gaaaatacaa gacctgattt
    15361 tgtacttgaa ctattagata ttatttcagt cagaggttat ggcagagtcc agatccaaga
    15421 acttgagggg aagacgaaaa aagaaaagta cagggtactg ttcggtgtat tacgtaaata
    15481 aaataaaaag gtggtttact catggcttta actccattag atatccaaaa taagacattc
    15541 ccgacaaaaa tgcggggata taatcaagac gaagtagatg atttcttaga tttagttgtt
    15601 cgtgactatg aggaattgac tcaaagaaat cgagaattag aaaaagcagt caaacattct
    15661 gaagaaaaac ttgagtactt caatgaatta aaagatgctt tgaaccaatc aatcatcgta
    15721 gctcaagata cggctgataa agtaaaaaca agtgcaagca aggaatccga agtgatcgtt
    15781 acttctgcac aaaacaaagc agatgagtta gttgcgaacg ctgaaaaacg tgcacatcaa
    15841 ttaacaactg atgcagaaga aaaagcaaga aaaatcttga cagatgcaac agaaaaagca
    15901 agacagcttg cgacagaaac tgaagatctt aagaaaaaaa cacgagtatt ccatcaacgt
    15961 atcagcttga tgcttgagtc tcaattagaa caagtgaaaa gtccggaatg ggatgaaatt
    16021 ttacaaccat tctccagcta cgtgactgac agccatgaag tgatcaaaga agttttagca
    16081 aaacagcttg acaatgaaaa tgatactgat gtaaactcag acacaggagt catagaagca
    16141 cctatgacgg catttgatac acaggctatt gatatctcga tcgtgcctgg tgaaaatgaa
    16201 aacgagtaga acagaaaagc actttgttat tcttaaagcg agccgatgag agtggaagtt
    16261 cggtaagaca ctgcatggtg aaagatcctc tacttgagac ctgcttttcc gaaattagag
    16321 taagaagcag cggctgacct cgttattggt cacagagagt ttgcactaga tagatgcaac
    16381 taaatttggg tggtaccacg gcatgttcgt cccttgcggc tgaacatgct tttttgtgtc
    16441 cggaaaacaa ataaaggagt gtatggttga atgaaaatga aagaaacctt gcaattagga
    16501 aaaacaaaat tccctatgcg tggtaatttg ccaaaccgag aaggcgagtg gcaaaaagaa
    16561 tgggaagaaa atcgaatcta ccaaaaaaga caagagttga acgaaggaaa acctagcttt
    16621 gttcttcatg atggacctcc atatgccaat ggtaatatcc atttaggaca ttcattgaat
    16681 aaaatcagta aagacattat cattcgttca aaatcaatgt ctggctatcg tgcaccatat
    16741 gttccaggat gggatacaca tggattgccg attgaacaag tattggctaa taaaggcgtg
    16801 aaacgtaaag aaatgtccat ggcagaatac ttggaaaaat gtcgtgaata tgcactttcc
    16861 caagtagata agcaacgagc agatttcaaa cgcctaggag ttgcaggaga ttgggaacat
    16921 ccttatgtta cattagatcc ttcttatgaa gctgcacaag tacgcgtatt tggtaaaatg
    16981 gctgaaaaag gctatattta caaaggattg aaaccaattt actggtctcc gtcaagtgag
    17041 tcttctttag cggaagctga aattgaatat aaagatgtaa aatctccatc tatttttgta
    17101 gctttcaatg tcaaagacgg caaagatatt cttgatgaag atacagcttt tgtcatttgg
    17161 acgacaacac catggacatt gccagcaaac caaggtattg ctgtaaatcc aaaatttacg
    17221 tatgtattgg tggaagccga tggccgtaag tttgtcgtag cgaaagattt gctagaaaca
    17281 gtccaatcag aaatcggttg ggaaaatgta acagttctaa aagaatttgc tggacaagaa
    17341 atggaatata tgactgcaag tcatccattc tatgaacgtg aatcacttgt gattttaggc
    17401 gatcatgtta ctttagacgc tggtactgga ttagtccata ctgctccagg acatggggaa
    17461 gatgactata tcgctggtag caaatataaa ctatctgtag tgtcacctgt agactcaaaa
    17521 ggattgttta cagaagaagc acctggattt gaaggtatct tttatgacaa agcaaatcct
    17581 atgatcactg atctattaaa agaaaaagga gctttgctga agctagattt ctttactcat
    17641 agttatcctc acgattggcg gacgaaaaag cctgtgatct atcgggcaac tccacaatgg
    17701 tttgcatcta tcgataaatt ccgtcagaat attttggatg aagtagaaaa agtagagtgg
    17761 gttatcccat ggggtaaaac acgtttgtat aatatgatcc gtgaccgcgg cgattgggta
    17821 atttcccgtc agcgtgcatg gggagtacca cttccgattt tctatgctga aaatggagaa
    17881 gcaatcatca caccagaaac aatcgaacat gtggcaaaat tatttgctga acatggatca
    17941 attatctggt ttgaaaaaga agcgaaagaa cttcttcctg aaggatttac ccacccaggt
    18001 tctcctaatg gcgaatttac aaaagaaaaa gatatcatgg atgtctggtt tgattctggt
    18061 tcttctcatg aagctgtttt acgtcagcga ccagaattat cattcccagc agatatgtat
    18121 ttagaaggat cagaccaata tcgtggctgg ttcaactcaa gtatcacgac tagtgtggct
    18181 atcaatggtg tagcaccata caaatcagtt atttctcaag gatttgcttt agatggtgaa
    18241 ggccgtaaga tgagtaaatc tttaggaaac atcattgcac cagaaaaagt gatcaaacaa
    18301 tttggtgcag atatccttcg cttatgggta tctagtgtag attatgaagc agatgttcgt
    18361 gtttctatgg atatcttaag tcaagtggca gaagtatatc gtaaaatcag aaatacgatg
    18421 cgtttcttat tagcgaatac agaagatttc gatcctaaaa aagatactgt ttcgtacaat
    18481 gatttacgtt ctgtagacaa atatatgacc gttcgattga accaagtaat caaagaaatc
    18541 cgagaagaag ggtacgacaa atataacttc atgcatattt accgtacagt tatgaacttc
    18601 ttgacggttg atctatcgtc attctacctg gattttgcta aagatgtagt ttatattgaa
    18661 gcagaagatg attatcaacg tcgttgcatg caaactgttt tctatcaaac agctgtagct
    18721 ttgacaaaat tattgactcc tatcattccg catacagcag aagaaatctg gtcattcctg
    18781 aaagaagaag aggagtacgt tcagttaagc gagtttcctg gttatgaaga gtttgcaaac
    18841 caagaagaat tgatggatac ctggactgct ttcatggact tccgtgataa tgtcttaaaa
    18901 gcattggaag aagcaagaaa cagcaaattg attggtaaat ctttggaagc aaaactaact
    18961 gtttatccaa aacaacaagt tcgtgaaatg ttaaaagctt tggatgcaga tattgcacaa
    19021 ttattgatcg tttcaccaga ctactttgaa gttatggcag cagatgaaca agtgccagat
    19081 aacgctatgg tatttgatga tgttgctatt acagtggaaa aagcagacgg ggaaacttgc
    19141 gatcgctgtc gccaagttcg taaagatgta ggagtagatg aaaaacttcc tcatctatgc
    19201 ggtcgttgtg caaaaatcgt tgaagacttc tatcctgaag ctgtagctga aggattcgaa
    19261 gaaaagtaaa agggaaaagg gggtgtgaca tgttctttgt cacaccccct tttgttatca
    19321 atcgtttaat tttccacgtt cacgatacca gttatctggt tgccagatcc attcgaatcc
    19381 gtctttttca agtagttcga aagctgcttt aggtcccatt gatccagctt tgtagttggg
    19441 aaaatccggt tgtgtttggt cccaagcttt tcgaatgaca tccacgatat gccaagattg
    19501 agcgacttct tcccaatgag agaagttcgt tccatcacca ttcaacgcat ctaatagtaa
    19561 tttttcgtaa gcttctgggc tattttcaac catttctgca ctatttctaa attccaattt
    19621 gattggttcc gtttcaaatc cttgccctac ttctttccca ttcaaggata aagaaaatcc
    19681 ttcagttggc tgaatataga tcgttagaac attaggtgga agtgtcgtat cgtcacatgg
    19741 ttcatcgaca gatgttttga atacattaac aggaacttgt ttgaatacga tgttgatccg
    19801 agtccctttt tcagtcaaac gtttgcctgt acgtacatag aaaggaacac ctgaccaacg
    19861 gaagttatcg atagtgaatt tgcctgcgac gaatgtttca gtctctgatt gagcatccac
    19921 tttgtcttct tcgcgatagc ccttgaattg tacaccatcc aattcacctt gagcatattg
    19981 cccgcgaacg aagttttcta acacttcttc ttcgttataa atgcggatag ctttcaatgc
    20041 tttgatcttt tctgtacgga tttctttttc ggaaaatgct actggcggtt ccattgcaag
    20101 taatgctaca acctgtaaaa tatgattttg caccatgtct ttaagtgcgc cactatgatc
    20161 gtagtagccc ccgcgatctt ctacaccgag gttttcgcca aaagtaattt ggatattgtc
    20221 gatatagcga ttgttccatt gagcctcaaa aatattattg gcaaaacgga tagctgagat
    20281 gttttggatc atttcttttc ctaaataatg atcaatcctg aaaatatctt gttctgggaa
    20341 tacttctctg atttgctggt tcaattcaaa agcagactgg taatcagaac cgaacggttt
    20401 ttctatgatc aaacgattga agccattttt tgtcataata ttttgtgatt tcaaatgaga
    20461 aacgatcgtt ccaaaaaatt gaggtgccat agccaaataa tagacacggt taccgtttaa
    20521 ttgatagtgt ccatctaatc ggtcagacaa ttcttttaat gtctgataat gcgttgaatc
    20581 atttacatca tgggattgat agtaaaaatg gcttgcaaag gtagttgctt cttcatctga
    20641 aggattcaat gcacggattg tttctttgac aacttcacgg tagtgctcat cgctccaggg
    20701 acggcgagcg gttccgatta cagcaaaatg ctcgcctaaa tttccttttc tgtaaaggcg
    20761 gaacaaagac gggtacaatt tacgctgggc taggtcacct gtaccgccga atatcgtaaa
    20821 caatacattt ttttcattag acatgtggat acactccttt atattttatc gacaaaaatc
    20881 gtgctggccg ccttaaagct gacggggatt ttctttctat cattttggat agtgatcggt
    20941 ccttcataag ctgcgatgtc aacgatctca tattcttcgt tgatattcag gtcaatagtg
    21001 actaagtaat ccaacaattc tttttcatca agcactcgtg cgatacgcac ttttgtaccg
    21061 acaggatagg actccaatgt ttgtcggcgt tcttcatgga caacttcctc ttttttagga
    21121 atcgatcctc catgaggaca atgttcagga tgattcaaat agttttctaa atgatctgca
    21181 agatgttccg aagtcacatg ttccaatact tcagcatcat catggacttc attccagcta
    21241 tagtctaaat gttcaactaa aaaaacttcc cataagcgat gtttgcgaat cagactgcta
    21301 gctttttgca gtccgcttgc agtcaattgt acaccttgat aaggggaatg ttctacaagc
    21361 tcttctttca caagtttaga aatcatttca ctgacagatg cagctgagac atctagacta
    21421 gatacgattt gtttattgtt gactttcgtt gtatctccac ctagttctaa aatgattttc
    21481 aaataatctt ctcgatttgg tgtcatattc gatcatcctt tcatggtaaa aaaccatcat
    21541 tagtaagtgt aacaaaaaaa acgttaattg actatttttc taaataaaaa acaaaggatt
    21601 tttagacgtt tttacaacaa aaaacgaaag atgatagaga agactcattc tttcgtttat
    21661 aaaggatata tatatacatt gggagggatc tatttttcag ataacaactt atatgaagtg
    21721 tctgcagatt cgtcataaag agtttgttcg ggataagaaa agataagata aaaaccatac
    21781 tgatcacgta cgactaaacg atattcatct atttctacca cagatgtgcc aagagactga
    21841 ccgttgatca aaaacgtgta atcagatgta atctgtaatt gttgtttttg ctggctatca
    21901 ctaaagaacc atgtaccttg atactttgag agtccttctg acttttccgc ttgttttttc
    21961 tttttcaagt aaataaaact tgagagaacg gtaatgagtg aaccaagaaa atagatcatt
    22021 ttttttatca ccaaatcact cctttatgag aaaataatcg catagacata ttctttcttc
    22081 tttatttcat tgtaccgaat aaaagctaaa atttctctaa gactttcgac tggttttttt
    22141 actgtttttc tacaaattat gataggatac atagtaggaa gaaaggtgac ataatttgaa
    22201 gtatcagcaa gtggaaatag ctttttttat tgaccgcccg aatcggttta tagcacattg
    22261 tatgaaaaaa gacggagaaa taattattgc gcatgtcaaa aatacaggta gaggaaaaga
    22321 ggtcctgata ccaggcgctg aagtggctat tgtatttgct cctggaccta aacggaaaac
    22381 cgcctatgat ctgattgctg taaaaaagaa gggtgactgg tttaatatcg atagtcaatt
    22441 gcctaatcgg ctggcaattg atggtatttt agacggcacg atccttttac caggattaac
    22501 tggtccattt acggtataca agcgtgaagt aacttatctt cactccaaat ttgatattta
    22561 tttagagacg gtggtcggac aaaaagcatt tgttgaagtc aaaggtatga cacttgaaaa
    22621 taaagcgatt ggtgcttttc ctgatgcgcc cacactcaga ggattgaaac atataggaga
    22681 attaacgtat gccgcacaag atggttatgc cgcttatgtc ttgtttattg ctcagttcga
    22741 acatcttcat ctggcaacga tccatgaaga aatgcaacca gcactagctg atatggttcg
    22801 acatgcgcag caaagcggag ttcaaatcct cgcctataat tgtcaagtat cggcagatga
    22861 ggtaactgtc aagcaggcca ttccatttga tgtagatatc ccttttgaag atcctataca
    22921 atagaaagaa ggtaaaataa tgatcaactt aggtattatc ggaacaaatt ggattactca
    22981 tcaatttgtc caagcagctt taagcacaaa aaaatatgaa ttgacagcgg tatattctag
    23041 acatttggaa aaagcacagg aatttggttc tcattatgaa ggggatatcg aattcgcaac
    23101 agatttgaag acttttttca atattactca tatggacacc atttatattg cttctccgaa
    23161 tagtcttcac tttagtcaag ctaagcaagc aattttggca ggaaaaaatg tgatagttga
    23221 aaagccagct ttttcgacgc caaaagaaat ggatgaaatc atccatttgg caaatgaaca
    23281 caatgtgtat ttttttgaag cagcaagaaa tatccatgaa tcaggtttta aaaagattgc
    23341 cgattactta ccattaaaag acgagataat cggtgcaaat ttcagctata tgaaatattc
    23401 ttcgcgctat gaccaagtat tagatggaga agaaccgaat atcttctcga ctcatttctc
    23461 aggtggtgca ttgatggatt taggtgttta ccttgtatat gcagctgttg cttggtttgg
    23521 aatgccaaaa gaagtccatt atttcccaag aaagatttct actggtgtag atggtcttgg
    23581 atgggggatc ttacgttatg agaattttga tgtatcgatc cagccaggta aaatcggtga
    23641 ttcttattta ccgtcagaga tttattttga ctcaggaacg ctagtgatga atggagtcaa
    23701 tgcaattgaa caagcacaat ttcatgatcg cgcgcataaa gaaatcattg atttggcggt
    23761 aacagctgca gaaaatccaa tggcagatga agcagaggat tttgccaatg tcatggctca
    23821 tccgaaagat ccagcttggg gattgttgta tgaagagtgg atcgagctag ctagaaatgt
    23881 gaaccaagtg atttatgatt taagaaaaaa tggcggcatc aaattcgatg cagataatga
    23941 ggaagatttt taatgaacga atttgtacaa gtatttcccg aaaattggca gaaaaaatat
    24001 gaggataaag ggtttatctc accttctctt attcaacgag cagtttttca gccactaagt
    24061 aataaacaaa gtatagtagc ggtttctcct acaggttcag gtaaaacact ggcttatctt
    24121 tggcctctac tactaaacgt ggaaccaggt gaagcaagtg cgttggtcat ttttgcttct
    24181 tctcaagaac tagctattca agtagcagat gttgcacgtg aatggggaaa agacaaagag
    24241 ttgaaagtcc aatctttggt gggcggagcc aacgtcaaac gtcagattga gggtttgaag
    24301 gaaaaaccag aaatcttgat tggtacacca ggaagaatat tggaattgat gaaagcaaaa
    24361 aaaataaaag cacatcaagt gaaaacaatg gtatttgatg aagcagacca gctatttgac
    24421 gctgggaaca gccaaatcat tgatcaaatt cttcatcaag ctccaacaga gtatcagcta
    24481 gctttttttt cagcgacagc agatcgttcc cttgaaagca ttgaaaaaat cactgggaaa
    24541 acgtttgaga caattgacgt gacagcagag gacgattctc gaaaaggact gagacattac
    24601 tttttacgtg taccgatacg aaagaaagat gactacttga gacgtctcac gcatatagaa
    24661 gattttcatg gtctgatttt ctttaatcaa ctgactgaat taggcgtaat ggaagaaaaa
    24721 ttgctgtata gaggtgtacc ggtaggaagt ctggcctctg atcagaacaa gctactccga
    24781 aaagcagcgc tagaacaatt caaaaagaaa atggtcagag cacttttgac cacagatgtg
    24841 gcggctagag gtttagatat tacaggtctt ccttatgtag tgaatgcaga agttccgtta
    24901 agtgaagaag cttatttgca tcgttcggga agaactggtc gaatgggtaa tgaaggaata
    24961 gtaattacac tcgtacaaga taataatcta agagatttaa aacggctttt acgtccatca
    25021 aatataacac ttgaagagat ttttttatac ggaggtaagc tgcaaactga gcagccaacc
    25081 aaagaagatg cagctcctgc agtaaataaa aagtatgcga aaactttttc tggaaaggag
    25141 cagaacccag aatataacaa agaaaaaata agaaaaaaag ttaaaaataa atcaaaaaaa
    25201 gagagaaata aaggagcaag gcgcaaataa gcgccttttt atgctatgat tatgaaaacg
    25261 ggaacaaaat tggttgccag aggaggggtt atgtgaaaga acgtcaagaa gagatcttgc
    25321 agctattgac agaaaaccaa caaggattga cagcaagtga tgtagctgag cgcttaacta
    25381 tcgatcgaag caatgcaagc cgatatttaa gtgaactata caaggcccat catattgtaa
    25441 aaaccgctgg ccgaccagtc gtttactctt tgccaacgga aaagtcaaaa tctgatgaag
    25501 tgcatgtcga ctcttctacg caagtgactt ttgaaacact cgttggagaa aatgattctt
    25561 taaaagtcag catacagcag gcaaaagctg cgattcttta tccaccgcgg gggttgcata
    25621 cgattatttt tggagaaact ggtacaggga agtcgatgtt tgctgaatgt atgtatcatt
    25681 ttgcaatcga ttcagagatg ctttctgcag atgcgccatt tgtttctttc aattgtgcgg
    25741 attatgctca aaatccgcaa ctgctctttg gacacatctt tgggatcaaa aaaggggctt
    25801 acacaggagc agctcaagat agtcccggtc taatagccaa agcagacggc ggtatattgt
    25861 ttttagatga gatccaccgt ttaccgccgg aagggcagga aatgctgttt actttcattg
    25921 ataaaggtat ttaccgtccg cttggagaaa gtgcacaagt acatgaagca tctgttcaga
    25981 tcattggggc gacgactgaa tcttcagaaa gtttcttatc tacgttcaat cgacggattc
    26041 ctatggcaat caccttgccg aatcttgctt cacgttcact ggatgagcgt tatgaaatca
    26101 tctctctttt tatcaaacaa gaagcgaatc gtttgaatca acgtatcgat atcgaaaaag
    26161 aagcgattct tgccttcatg ctttatgatg cggaaggaaa tatcggtcaa gtgaaacgag
    26221 acttgaaact agtctgtgca aaatcttttt tacattaccg tactcatcat gagaaaaagc
    26281 taatcattcg aaaagaagaa ctttcccttc aagtacaaaa aggattactg aaaatcaagg
    26341 aaataccgga acgtctcgac cgattcatgg acagcaaaag tcagtatttg acatttgaac
    26401 caggatttgc tgatgttgtc tggtcacaag atccagaacg aaacatgcag gtctataacg
    26461 atattgagga aaaagtcact tctctttccg aaaccggtgt ggagaacatt gatctagaga
    26521 ccctcatttc aaaagatgtg gatgcttatt tccagacata tgtcaaagaa ttgactaaaa
    26581 gttcgattcc caaagatctt ttgccagatg aaatctggcg gttaaccaat caattgtatg
    26641 atgtggctga aaaacggtta gaccgtattt ataatgaaaa agctcgtttt gcttttgctt
    26701 tgcatctgca aagtacattg gatcgtgtga gagaaggtca tatgatcgtc cacccagatt
    26761 tgaataacgt acggaaaaat tttaagaggg aattccaggt agcaatcgat ctttcaacga
    26821 tcattgaaga agaagaacaa gttgagattc cttttgatga aatcggcttt attagtatgt
    26881 ttctttctat caatctagga gaaagtgagc ctgttaaaga aaacaaagta gatgttctca
    26941 tattgatgca cggcagacag actgcttcaa gcatgttgga gatggcacaa gaactattag
    27001 gaacaaaagt agggaaagct tttaatatgc cactggttat ggaagttcaa acaatgtatg
    27061 aagaagtgtt acaatatgtc aaaaactatc aagagcattt gacgaatggc ctactcttgt
    27121 taacagatat gggatcatta aacaccttca gtgatttgat ttatgaagag actggcattc
    27181 ggacgaaagc tatcacgatg acaagtacca tgattgtgat agaagcgata cggatggcaa
    27241 gtgttggaag aagcttagaa gatatttatc aaaatatcca gctttccttt gaatcgatcg
    27301 tacgtgatca gttcaaagcg gaaaagtctg aaactttaca gcgtaaaaaa gccgtaatcg
    27361 tgacatgctt tactggtgaa ggagtagctg ccaaattata tcagcgtatt atgccagtga
    27421 ttaatcaaaa taaggtagaa ctgatccaga tgcagttttt agaacgtgaa tcattcaaaa
    27481 aacacatcga tgccttattg gaagaatatg agatcaaagc aattgcggga acagttgatg
    27541 ttgattatca aaatatccca tttttttcag cctatgacgt ttttgatgat gaaaaactaa
    27601 atattttaaa gcgtatagct gatgatgaga tcccgacagc taaaattgtc gattcacttg
    27661 ctggatcatt aagcgatgtc ttttctattg atgaactgat ccgttcattg caaaagacag
    27721 ttcagcagat ccagaccgat ttgtcgatta tcgtggaacc tggagtagat actggaatcg
    27781 ttatccattt agccttcatg ttagacggat tgatcaaaca agaaagccat cggcaatttg
    27841 agaaactgtc tattttctca aaaatttatc gtttggaaat ggatatcgtt cgggcaaact
    27901 tgatggcact agaacgaaaa tatcaggtaa aaattccaga agatgatatc gcatttctta
    27961 cacaaatgtt tcttgaaaat aaaataaaaa aatgaacaca ctaatcatac tgtttacaca
    28021 ctaaacatct gtgtgcgcac tataaaaaag agctaaaaag catgaaaacg ctatttcagc
    28081 tctttttttt attggcatgc ttcttgcgtt atataaaagt gtaaaaaaat aaaaggagtg
    28141 ttaaaaatgg caaaaaaaac aatcatgtta gtttgttcag cagggatgag tacgagttta
    28201 ttggtcacaa aaatgcaaaa agcagcagaa gaaaaaggga tggaagccga tatttttgcg
    28261 gtctctgcct cagatgcaga taataattta gaatctaaga atgtcgatgt attattatta
    28321 ggtcctcaag tacgtttcat gaaagctcaa tttgaacaaa aacttgcgcc taaaggtatt
    28381 ccattagatg tcatcaatat gcaagactat ggcatgatga acggagaaaa agttcttgca
    28441 caagcagaaa atctaatgaa ataaatcaag tatgcagttg ggggtataac aacgtggaag
    28501 atcaacaaaa tctagaagcc atcatggggt taatcatgtt tggcggtaat gcaaagagcg
    28561 atgcaatgga agcgattgcg gctgctaaaa tcggtgattt tgagttagcg gataggaaaa
    28621 tcgctgatgc agaagaatca cttatacaag cgcatcatgc acaaacagac atgttgacac
    28681 aagaagcaca aggaaatcat atgcaagtga cattattgac tgttcacagt caagatcact
    28741 taatgacatc tattgcgttt actgatttag caaaagaaat catcgaactt tatcgtcgcg
    28801 tatacagcga ataaatacaa cttctttttt gaacggaaga agaaaaattt ttgaacggat
    28861 tttttatttt gttataagga gaactctctt tatataaaaa acttatagga ggaagtaaaa
    28921 aatgaacgga ctatcaagtt ggatggagaa atacatcctg ccggttgccg caaaaatcgg
    28981 agcgcaaaaa catttagttg ctttgcgtga tgcttttatc ggcatactgc ccgcaacaat
    29041 ggcgggatca gtcgctgtaa tgatcaatgc aattattcgt gatttaccgc aacagtttaa
    29101 cagtacctat gctgacagtt tagcagcaga caaaggaatc tttgccgtat tgaatgtcat
    29161 catcggaatc aatggttttg tctggaacgg tacactagca atcgccggat tgatctttgc
    29221 cttttcttgg gggtataatc ttgcccgagc ttatggagta aatgatctag ctggggggat
    29281 cgttggttta gctaccttga ttcaaggtat ttcctttggt ccagcattat cagcagcatt
    29341 agatgtgaat gttccttcaa atgtcgcaga tgcaatcaat agttctgaga ttggtgcaac
    29401 gattgcagat ggcacactgt cagttggatt atggggttgg ctaaaactag atcatttgaa
    29461 tggaaacgct tattttacag ttatgatcat gggagctatt tcagtcatta ttttttgtaa
    29521 attgatgctt gccaacatta cgatcaaaat gcctgattca gtaccaccag cagtatctaa
    29581 agcatttgca gccattttac cagcgacgat cgctttatac gtcattgcta ttatcaatta
    29641 tatcgtaggt cgtgtagctg atgggcaact gatcattgat ttggtgcaaa aatatattgc
    29701 agaaccattc ctaggattat ctcaagggtt gggagcagta ttgatcgtca cagtatttgt
    29761 tcaagtattc tggttctttg gtattcatgg atcaaatgta ttggcaccag tgctagaggg
    29821 aatctgggga caagcacaac taatcaatat tgatattttc caaaaaggtt ataacggaaa
    29881 aactggtaca ccagccgtgt tagatgcaat cgaagatgga aaagcttata tgtgggtccg
    29941 cggatcgttc gatgcttttg catggtttgg cggatcaggc ggaacgatcg tcttactgat
    30001 agctatcttg attttctcta aacgtgcaga ttatctaaca gtagctaaat tatccattgg
    30061 gcctggtatc ttcaatatca acgaaccagt gatgtttggt ctgccaatcg tattgaatgc
    30121 aatcatgttt atcccattct tgattgctcc agtagtagca acagcaattg gatggacagc
    30181 tacttatctt ggcctagtcg ctccggtatc gcagcaagtc acatgggtag taccgccgtt
    30241 cttattgtca ttcttagcaa caggagcgga ttggcgggca ccgatcgtaa cattagtatg
    30301 tatggtcgtg actttcttga tttgggcacc atttgtcatc tctgcaaaca aaatggaccc
    30361 tgccgcaggc gaacaacaat aagatgaacg tgaggagcgg gacgctttaa gtttcgttcc
    30421 tcataatgaa ttttcgagga ggaactgaaa tgattacaat tgccagtgca atgcaacaag
    30481 atgaaatcaa agaattgtta gaaggataca atgaagaagg aatgactttt acatttaaag
    30541 aaaaacaagg aatcaagctg ttctttgaaa caagtgcaga agatccggaa gttgcggcta
    30601 aaaaagcaaa ggaactaatc aaagcacagc cttggggaac agtcctttat tttcaatcaa
    30661 cagctgttta gaaaatggtt taaaaagata ggatggttga gatgataaaa aacggtttat
    30721 ttttatgtag tattggttct ttgatcgtgt tgtatagttt gaatccacat tcgcaaaggt
    30781 atgatttgta tagtatggtc acaggtcttt ttctaacagg attaggaatc tatttcttca
    30841 tgaaggggaa aaaaagagaa gaagcaaagg agaaaaataa ctaatggaaa tcacgaaaaa
    30901 attaaatatt ccagcatcgt ttttttacga taaagttatg gactctgtcc ttttcgatgt
    30961 acgtaaagcg accggcaaat cagtaactag aaaacagctg aaaaatttgg agtacgtcaa
    31021 acaattctcg caaaataacc gggctcgcat aaaaatcgaa gaagtcattg aaaaccagtc
    31081 ttataagttt cgtacatcga caacgaagaa tgaattcgtc gttcattatc aaatcaaacc
    31141 attggacgat tcgacctgtg aggttcatta cacagaaaaa atggagtctt atggcatgct
    31201 tcaaaagttg aatgatatgc ttttaggaac aatcttgatg tattttaaac ggagacgttt
    31261 caaaaaaatg ctagatatga tcgaagcaac gtattaaatc aatgaaacat ggtactattt
    31321 agttattgaa aaatgaagta agctagaagg aatttttcat aggaagatag atctttcctg
    31381 cgaatcctca ctagcttttt tgtaggaagg ggcagcaaaa tgacaaacaa agtaagagag
    31441 ctaggtgtat cttcgattga ggaaatgttt gatttagcca cttatgcatt taatggggca
    31501 gatacacctg aaaggcgaga acgttttcgt acacttgcgg agaattcttg gaattacgga
    31561 ttttttgatg aggaggatcg gctaacaagt caagtcatgg cgaccccttt tccagtgaat
    31621 ttttacggac aagagtacct aatggccggc attggctatg ttgcttctta tccagaagca
    31681 aggggacaag gcgggatcaa tcagatcatg gaaaagatcc ttgaagattg ccgtgatcgt
    31741 aaagtaagct tatcttatct ggcgccattc tcctatccct tctatcggcg ctatggctat
    31801 gaacaatcat ttgataaaat cagttatcaa ctaaacagtc gtgatgtgcc gtttatcaaa
    31861 aaaaaatctg gaaaaataaa gcgtatggat tttgaagatg caaaagctgc aatcagaaga
    31921 atttatgaac agatgccgga aaaccaacga gctggtctga agcgcgaaga ctggtggtat
    31981 acgtataaat tcaagcaaaa aggcaattac cagtttgctt tgcattttga tgataatgag
    32041 gaagcaacgg gatatatcgt ttatcagctt gcaacgtctt cctttattat tgcggagtgg
    32101 ggatttttgg atcatgatgc tttttgcagc cttgttcgct tcgtaagttc tcacaatggt
    32161 gcttttgaaa catttgaata ttcatgcggc tacggcggta atgatcaaaa ttatctatta
    32221 gaaaatccat ttgcttctgt aatgatcaca ccttatatga tggcgaggat cgtagatatt
    32281 tctttgtttt tggaaaatta tccatttaaa aagagacaag ctgcatttgc cctacaaata
    32341 gaagaagatc attatgcgaa atggaatgaa ggaatcgtgg aagtaacaat cgaaaatgga
    32401 aaaaatcatc tctcaaaagt agaacaaaca aaactcccaa tcgttcgagg aagtatccaa
    32461 catatcacgc agctattatt agggtatcgt aaagtggaag agttggtatt ccaagaaaga
    32521 atacaggtga caaaagaata tgaagaaacg ttaagctcaa tcttgccaca gcaacagcca
    32581 attcttaatg actatttttg ataaaaaacg ggtgatgaca atatttttgt caccaccctt
    32641 ttgtttttca tttggcattt gaaggaaaat gttaaagtaa atcctctttt ttcgtaaatt
    32701 tgaatttttt gttttctttt gttttagggt tttctttttt gtggtcttgg attgcttctt
    32761 tcgtaatctt ttcccgattt tttttagatg aatctaagcg ttctgcgtat actttttctt
    32821 ttggcttatc attcattgga aaggacctcc ctacattatt tcattctacc tctagtttat
    32881 catctgttaa ggactagtgg aaacgttttg cctaacttat aagctgattt ttttagcaga
    32941 taagcttgca agtaaaaaac aaacaagcta caattgattt attgaaattg ttcctgtagc
    33001 tcagtaggat agagcaatcg cctcctaagc gataggtcgc tggttcaatt ccagtcagga
    33061 acgtataaat aacccctgta tcctttgcgg tacaggggtt tgttttgtat ttgtgccaaa
    33121 aatgtgccaa actagttatc atttttatat aaactatcga acacagtatt gattttttct
    33181 ttatcctgat cttcaagctc tcgaacaata tgaagataag tagacattgt agtttctaaa
    33241 ctgctatgtc ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata
    33301 gatgcatgtg tatgccttag tccatgcaaa gtaaattgct tttcaatccc taattctttt
    33361 aattttttgc gcaaatattt gctgacggcg tttgatgaaa ctaatccatt ttttaagttg
    33421 aaaaaaacaa aattatgagg gtttttgatt tcaaaattct cgaataattc tttttgattg
    33481 attttaaact tttttaagag atcaatcgta tgtttatcaa tggaaatttt cctatttgaa
    33541 gtttcgtttt ttgtttttcc ccattcattt aatttataat tccatgtttt attaatagtg
    33601 atgatttgat cttcgaaatc gatatcttcc catgttaatc ctagaagttc agcaaatcgc
    33661 attccagtgg caccagcaac taacacgagc ataggagaag agtactgcgc agaaaggttt
    33721 tcttctacga gtttcattaa agatttaaat tgatcataat ctaaatattt atcttctttt
    33781 ggcttcaatg aatcttttcc tttgattact gcttttctag ttggatcaaa cggaattaat
    33841 ccttcttcta cggcatcttt caacgacgct ctaatatggt tattaaactt aataacggta
    33901 gattttacat ggtctttagc atacttattt aaaaagcgtt gatatcccac tctatctaaa
    33961 tcagaaatca ataccgctgg catatatttc tttatgttca ttaacgtatc ttcgtatttt
    34021 ctataagtga taggagatac tgttccttct ttataaagtt gcatccaatc ctcaaagtaa
    34081 tctgataata atagattttt gcgatcccct ttaaggcctt tgttcaagtt atattctaat
    34141 tcgttggcgg catcttttgc ttctcctttt gtcttaaatc ctgattttct tatcttcgtg
    34201 tattttccgt catctttttt gtatgaaatt tcgtattgcc aactatttcc acgtttgact
    34261 aatcttgcca taattgaatc agctctcttt ctctgataca ataggaacta taaagaagcc
    34321 cattgtttgg gttttattat tttttgcaca tcctttttgc ttgccggcgc aaggatgtgc
    34381 tatttgtcgt tttaatggta taattggatg tgtattagat catccaatca gaggtgttta
    34441 ttatgattaa agtgattttt aaaagaataa ctgaacttcc agagtttaga ttatttgttg
    34501 attattggta tgtctggttt tttattgttg cattgctgat aggtctagat gtcatattag
    34561 aaagaaaact taagtaagag ttgagttaat aaattgaatt cctaaatgag atattttgta
    34621 gcccatattt tgtttgccga catcacctaa tactatggag ctaatcgttt tttctaacag
    34681 accaaaatca gataatctat ttaagctacc atctattagc tcttgtgaat agccagacat
    34741 gctgatattt ccagtgaaat tttcgtttcc acgactcatt aagcatgcta acaattgaat
    34801 ctcaatcgat gttaattgat tcagtacaag aagataatac tcctcgttat cccatgaagc
    34861 gttgttaatt cgaagtaaac aattcttata aagattttta tacatatcta ttttattttg
    34921 tgcctttgat ttttctacct cgtcatttat cccttcgaat attccaatga gttggtcctt
    34981 gttctctaag ttgaaaacat cttctggaat ttgatcgcga atgttttcta atgattcgtt
    35041 taaatttttg tagaatttct cgatgcgttt gaaacgcttc tcgtttttag acccaaaata
    35101 aagtgactgc acaacgccac caatataagg aattgctcca ataccgcctt caactattaa
    35161 ttcaagatat tcttttttgg ttagtttttc attgctatta tccatagtta cctcctattt
    35221 tgtcatttcc tttacaagca ttgtgactcc tgatggcact cttttgtata ggttttatta
    35281 ttgtgcacaa tctaactctt agtggggcgt ggttcattta ttttttactt actttactat
    35341 taatcatatc ccattgagca taggattttt ctatgttcga tcctcttgaa ctaatttctc
    35401 ctgtaaaagt tactttatcg ccctttgtaa aggtatcagc attgtttaag tccttcgcaa
    35461 aaattacata tgaaacttta ggtgttgcag aaatatcatt ccaactttta tcatcgtact
    35521 ctttgtctgc tataatggct attctagtag tcattgattc gataacagtt ccttcaaaag
    35581 tatatgtttt accactaata tatttagtaa aagctgtatt ttgctcagta gctggagtaa
    35641 tagaataata actatctaag aaagcacccc agtcatgatt atttgtctct aaaaattctt
    35701 caaattgagt taggctttta ttgctgctgt tagatgtagt agtttgagta tcagatgatg
    35761 agctttcctg tttgttattg tcatttgcct cgtttgatga ggaaagcgag aaacctacgg
    35821 tagtaaaaat aatcccgata ataaggagaa tcataggtgt tttcttattt gtttttttga
    35881 taaatcttac aattaacatg attaaaccta taataaataa aacaatacca gtaaaaccaa
    35941 atataccgtc cattaataga tcctctttct cttttgatat tgaatattat aaaccaagca
    36001 attctttttt cttaaaatcg aattcttctt gattaataat cccttcatct aacaactctt
    36061 tatacttttt aatttcatct gcacttgaaa tttgtgtttc tttggaa
//
LOCUS       DADVXV010000018        35537 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.018, whole genome shotgun sequence.
ACCESSION   DADVXV010000018 DADVXV010000000
VERSION     DADVXV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.018"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            217..1983
                     /locus_tag="KB969_000872"
     CDS             217..1983
                     /locus_tag="KB969_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBB6868880.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2085..3344
                     /locus_tag="KB969_000873"
     CDS             2085..3344
                     /locus_tag="KB969_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6868881.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3491..4792
                     /locus_tag="KB969_000874"
     CDS             3491..4792
                     /locus_tag="KB969_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868882.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4795..5646
                     /locus_tag="KB969_000875"
     CDS             4795..5646
                     /locus_tag="KB969_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868883.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5659..6474
                     /locus_tag="KB969_000876"
     CDS             5659..6474
                     /locus_tag="KB969_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBB6868884.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6625..7791
                     /locus_tag="KB969_000877"
     CDS             6625..7791
                     /locus_tag="KB969_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6868885.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            8021..8668
                     /locus_tag="KB969_000878"
     CDS             8021..8668
                     /locus_tag="KB969_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBB6868886.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            8752..9696
                     /locus_tag="KB969_000879"
     CDS             8752..9696
                     /locus_tag="KB969_000879"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBB6868887.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            9831..11282
                     /locus_tag="KB969_000880"
     CDS             9831..11282
                     /locus_tag="KB969_000880"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBB6868888.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            11303..12139
                     /locus_tag="KB969_000881"
     CDS             11303..12139
                     /locus_tag="KB969_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBB6868889.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            12139..12798
                     /locus_tag="KB969_000882"
     CDS             12139..12798
                     /locus_tag="KB969_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6868890.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            12924..13613
                     /locus_tag="KB969_000883"
     CDS             12924..13613
                     /locus_tag="KB969_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868891.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            13619..14575
                     /locus_tag="KB969_000884"
     CDS             13619..14575
                     /locus_tag="KB969_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBB6868892.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            14619..15131
                     /locus_tag="KB969_000885"
     CDS             14619..15131
                     /locus_tag="KB969_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868893.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(15387..15935)
                     /locus_tag="KB969_000886"
     CDS             complement(15387..15935)
                     /locus_tag="KB969_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6868894.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(16024..17205)
                     /locus_tag="KB969_000887"
     CDS             complement(16024..17205)
                     /locus_tag="KB969_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBB6868895.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(17441..18949)
                     /locus_tag="KB969_000888"
     CDS             complement(17441..18949)
                     /locus_tag="KB969_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBB6868896.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            19108..19299
                     /locus_tag="KB969_000889"
     CDS             19108..19299
                     /locus_tag="KB969_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868897.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            19502..20419
                     /locus_tag="KB969_000890"
     CDS             19502..20419
                     /locus_tag="KB969_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBB6868898.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            20412..21485
                     /locus_tag="KB969_000891"
     CDS             20412..21485
                     /locus_tag="KB969_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868899.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            21633..22151
                     /locus_tag="KB969_000892"
     CDS             21633..22151
                     /locus_tag="KB969_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868900.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            22132..22524
                     /locus_tag="KB969_000893"
     CDS             22132..22524
                     /locus_tag="KB969_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBB6868901.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            22600..23535
                     /locus_tag="KB969_000894"
     CDS             22600..23535
                     /locus_tag="KB969_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBB6868902.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            23668..24447
                     /locus_tag="KB969_000895"
     CDS             23668..24447
                     /locus_tag="KB969_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBB6868903.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            24440..24757
                     /locus_tag="KB969_000896"
     CDS             24440..24757
                     /locus_tag="KB969_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBB6868904.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            25001..26611
                     /locus_tag="KB969_000897"
     CDS             25001..26611
                     /locus_tag="KB969_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6868905.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            26768..27616
                     /locus_tag="KB969_000898"
     CDS             26768..27616
                     /locus_tag="KB969_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6868906.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            27847..28326
                     /locus_tag="KB969_000899"
     CDS             27847..28326
                     /locus_tag="KB969_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868907.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            28359..30587
                     /locus_tag="KB969_000900"
     CDS             28359..30587
                     /locus_tag="KB969_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6868908.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            30716..32359
                     /locus_tag="KB969_000901"
     CDS             30716..32359
                     /locus_tag="KB969_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBB6868909.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(32432..32977)
                     /locus_tag="KB969_000902"
     CDS             complement(32432..32977)
                     /locus_tag="KB969_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBB6868910.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(33000..33485)
                     /locus_tag="KB969_000903"
     CDS             complement(33000..33485)
                     /locus_tag="KB969_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6868911.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(33475..34287)
                     /locus_tag="KB969_000904"
     CDS             complement(33475..34287)
                     /locus_tag="KB969_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBB6868912.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(34426..>35537)
                     /locus_tag="KB969_000905"
     CDS             complement(34426..>35537)
                     /locus_tag="KB969_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBB6868913.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        11626 a         6395 c         7110 g        10406 t
ORIGIN      
        1 tggagaaatt gatcgcttaa gataaattca ggacactaaa tagtacagga agtagactaa
       61 aacttttaaa agttttaagt ctatctattt ggcaagttta aaaaataaaa attcggtatc
      121 aaaaaactgt taccgataac atttttgaaa gcgttgtctt ttgcttctct atcacttata
      181 gtgatgacgt catattaaaa cacaaggagg aaatcaatgg atacagctgc aatttatcat
      241 cgaccggaaa gtgaatatgc atttctatat acgaatacaa gatttcgtat tcggcttcgt
      301 actaggaaaa atgatatcaa aaaagtatat gtgctatgtg gagatccata taccataaca
      361 actgaaaaat ggtatcaaaa acaacgacca atgaaaaaat gtctaagtac caatgttcat
      421 gattattggg aaattgaagt gacgagcgaa acaagtcgct tacagtatgc gttccatgtt
      481 gttggggaag ataacacgga ctgtttttac ggtgatcaag gaatttttcc ttatcgagaa
      541 aatgtgatta ctgaaccaaa tttttatttt cgaatacctt attttcatca aatcgatcga
      601 ttcactattc cagaatgggt aaaagaaaca gtatggtatc aaatttttcc cgaaagattt
      661 gcaaacgggg acaaagcaaa tgaccccgaa cacactttac cttggggaag taaagatcca
      721 gaccgagaag actttttcgg gggagatttg caaggtgtga tggatcattt ggattacttg
      781 acggaccttg gcatcaatgg catctatttt tgtcccatat ttaaagccac atccaatcat
      841 aaatacgata cgattgatta ttatgaggtg gatcccgctt ttggcgataa aaaactttta
      901 aaaaacttga ttgatgaagc acataaaaga gggatacgta tcatgttcga tgctgtattc
      961 aatcatatgg gtgtccattc accacagtgg caagacgttc tcaaaaacgg agaaaaatcg
     1021 atctataaag actggttcca catccgtttt ttcccagtag attcttatca gatgactgac
     1081 ttaccagaaa ctgctgaaaa tatcccatat gatacttttg cttttactcc attcatgccg
     1141 aaactaaata cagcaaatcc agaagtgcaa aaatatttgc tggatatcgc aacttattgg
     1201 ataaaagaat tcgatattga tggatggcgt cttgatgttg ctaatgaagt cgatcatcat
     1261 ttttggaaaa aattcagaga agcagttaca gaaatcaaac cagacatcta tatccttgga
     1321 gagatttggc attcctctca agcttggctg caaggggatg aattccatgc agtgatgaat
     1381 tatgcattta cagattcgat taaagattat tttgcaaaaa agaaaatcac agcttcacaa
     1441 atggtcagtg gaatgaatca tcagcaaatg ctttacagag atcaggtgaa cgaaggaaca
     1501 ttcaacttat tagattctca tgatactgcc aggatcttga ccctttgcca aggtaacaaa
     1561 gaattgatga agtctgtgat ggcctttatg tttcttcaaa aagggtctcc ttgtatctat
     1621 tacgggacag aaatagggat gactggtgaa gatgacccgg attgccgcaa atgtatgata
     1681 tgggagaagg aggaacaaga tctagagcta ttcggtttta taaaagaact tgtttctcta
     1741 aggaaacagt tgtctaagat tatttctgaa ggttctactc agtggctaat agtaaatgat
     1801 cgtgaagata agctctattt cacacggaaa ctagagggac agatcatcta tgtttacttt
     1861 aatcagtcaa aagaaccttg ggtagtagaa caggaaaatg aggtgattct tagtcaaaat
     1921 tgtcagttgt tagaagacgg gaaagcagag atacgacaat acggattttt gatcatgtgt
     1981 tgaaaactgt taccggtaac aacaagaaag cgtttgcaaa tgaagatttg tgcccattat
     2041 aataagggtg taacagcacg ttgaatacaa aggaggaaat gaagatgaaa aaaagaagtg
     2101 tgaaacagtt gggtttaggg ttaatctctt taggaatctt aggcggatta gcggcttgtg
     2161 gcaatggtaa ctcttcagca gaaggggaag ccgatgaagg aaaaacgtta acagtttccg
     2221 ttgattctgg atataaagat tatataaacg aaataaaaaa cactttcgaa aaagaaaacg
     2281 atgtgaaaat caagctagta gaaaaggaca tgttcgatca gttggaatca ttagcgttag
     2341 atgggcctgc tggaaaggga cctgacgtta tgatggcagc atatgaccgg atcggtgcgt
     2401 taggacagca aggacatctg gcggaagtaa aactgggaaa tgaagcagct tacgatgaaa
     2461 cagacaaagc ccaagtgact tatgatggaa aaatctacgg agaacctgca gtaatcgaga
     2521 cccttgtttt gtactataac aaagatttag tcgatacagc accatcaacg tttaaagatt
     2581 tggagaatct atccaaagac agtcgttttg cttttgagtc agaagcagga aaaaatacag
     2641 gatttttagc taaatggact gacttttatt attcctatgg tttaattgca ggttacggtg
     2701 gctatgtatt tggtgatgat ggcacaaatc cttcagatat cggtttgaat aatgcaggtg
     2761 ctgtagaagg aatctcttat gcaacagatt ggttcaaaaa tgtttggcca aagggaatgc
     2821 aagacataaa aagtgcagga gacttcgcca gccagcaatt catgtccaat aaaactgcag
     2881 caatcattga cggtccatgg caagcgcaaa catacaaaga aaacaatatc aattatggtg
     2941 tagccaaaat tcctactcta aataatggac agccttatca accgtttggc ggaggaaaag
     3001 gatgggtagt cagcaattat gctaaaaaca aagacctctc tcaaaaatgg cttgattatg
     3061 taacgaatca ggaaaatcaa gaaaaattct ttgaaatggt aaatgaaatc cctgcaaacc
     3121 aacaagctag ggaaacagca aaggctaaaa acgatgaatt aacaacagct gtgattgaac
     3181 aatatgaaac agctcaagcg atgccaaaca tcccagaaat gggcgaagtt tggacaggtg
     3241 cagaaaactt gatgttcgat gcagcatcag gttcaaaaac accaaaagaa tccgcagatg
     3301 aagcagtaaa aacaatcagt gaagccatag aacaaaaata ctgattaaaa tgataaccgt
     3361 ccatttttat aaaaaatgga acaggtgctt cagataaaag tggcaagagc gagatggaaa
     3421 attatcttgc tcttgttgcc attatcttaa aagcagtttg cggtttagca agtttagagg
     3481 gggcattcag atgcagcaag ataaaacaag caatatcaac gaaaaaaaaa tcacgctttg
     3541 ttcacttatt ccagggatgg ggcagtttgt aaatggccaa gcttttaaag gtatcgtttt
     3601 tttcgccata ttcgtcctat tcattggtca gatgcttctg ggcggatttc atgcattggt
     3661 aggattggtt actttgggaa gtataccaat ggaagatcat tcattattta ttttgattga
     3721 aggcactttg caattcatca ttacaatcat tttcttgatt ttttacggtt tgaatctttt
     3781 agacgcttat cgagtagcga agatgcgtca agagggcaaa aaaatcaatc ggacgatgaa
     3841 ggaagtcata cataatatag gtgatgaagg ttttccttat ctattgacac ttcccgctta
     3901 tcttctcatg atttttacga tcattttccc agtcctagtt acattgttca ctgcatttac
     3961 taattatgac ttcaatcata ttccaccagc cagtttaatt gattgggtag gggctaaaaa
     4021 cttttttagt atcttctttt taagctcata tcgtaatact ttttttgcag tcttttcgtg
     4081 gaccgtgatt tggactttat gtgcaacaac tttgcaaatc acccttggta ttctcacagc
     4141 ggttgttgct caccagaaat ttattaaatt caaacgtatt ttcggtatca ttttcttatt
     4201 accatgggcg gtcccagctt ttattactat catgagtttt tcgaatatat tcaacgatag
     4261 cgtaggtgcc atcaatactc aagtgattcc tttcataaac cagcttcctt ttgtagatat
     4321 cagtgcaatc tcttggaaaa cggacccgaa ctggacgaaa gtagcaatta tcttagtgca
     4381 gggctggtta ggatttccct atatctatgt gatggttaca ggaatcttac aatcgatttc
     4441 agaagactta tatgaagcag caaaaatcga cggagcaaat gcatggcagc gcttttcaaa
     4501 catcacgctt cctgctgtct tcctagtggc agcgccaaca tttattacac agtatacggg
     4561 gaatttcaat aatttctcca tgatctatct gtttaacaat ggcggtcccg gaagcgtagg
     4621 cggaggagct ggttctactg atattcttat ttcctggatc tataaactta cgactggaac
     4681 ttctccgcag tattctatgg cttcagcaat cacgttgatt atctccgtca tcgttatctg
     4741 tgtgtcattg ctggtattta aaaagacaaa tgcgttcaat atgggggatt aacaatgaaa
     4801 aaatttcatt cgagtgctcg attccaaaaa cgactttctc acttttttac ttactttttt
     4861 cttttaatac tgtcagtcat tatcatctat ccgcttttga tcacagcaag tactgccttc
     4921 aagtcaggaa atattgcagc ttttagttta gatctttcaa gtgactggac tttaggaaac
     4981 tttactcggc tattcagtga aacactttac gggacttggt ataaaaatac attgatcatt
     5041 tctgtcctaa caatgatcgt acaagtgact gtagtaactt tggcgggcta tacttatagt
     5101 cgctatcgtt ttatcggccg caaatcaagt ctgatgttct ttttagtgat tcagatggta
     5161 ccgactatgg cagcattgac tgccttttat gtcatggctt tcttattaga agcgctcgat
     5221 aagtactggt tcttgacaat gatctatata ggcggtggaa ttccaatgaa tacttggctg
     5281 atgaaaggat actttgacac tgtaccaata gatttagatg aatctgctaa acttgatggg
     5341 gcagggcatt tcaggatttt tttccagatt gtattaccgc ttgtcaaacc gatgctcgcc
     5401 gttcaagcat tatgggcttt tatgggacct tttggggatt tcatgttagc taagttcctg
     5461 cttcgaacac ctgaaaatca gactgttgct gtcggcttac aaacatttat ttctgatgtg
     5521 acaaaccaaa gagtctctct ttttgctgct ggggcaattt tgattgcact accgatttgt
     5581 ctattattct tctttttaca aaagaacttt gttaccggcc tgacatctgg cggaacaaaa
     5641 ggataggagc agagtatcat gcaaacattt ccgttaaact atttttccgc attacgtacg
     5701 ccaactcaag tgtttgcggg acgcaaacta ttatcatggc ctaaattttt cttgatattt
     5761 gtatttttag tttccttgat ggtcatgcct gtgactcttt tttatgccaa tcagatccaa
     5821 gcgattccat tagaacaatt tctatccgtt cattcgctga tcgatgaaca aggaacccaa
     5881 aaattttctg aacttgaatt atctgaaact gggttacaag catcgcaaca aacgatagct
     5941 gtgacccctg aaattttggt aggtgtgtct ttatctgaga aacaacaatc cgatcatgga
     6001 acttttattg attttgagaa ggaacaatgg gtgatccaac aaaaggataa atctggtata
     6061 cgccgctata cgatgaatta tagcccatct ttccaaccag attctgtacg tacgcccgaa
     6121 gatttccaac gatttttaga aagagaattt tatgccagta atcgtccaac aatcatttta
     6181 tcttatagtt taagtcttgg tcttgtccta tttgtcatga cgagtctcat tttattcggg
     6241 gcttcctttt tcttgtggat gacaagaaaa agccaacttt catccattca tacattcaaa
     6301 gagagtgcaa atttgatgct gaatgttatg ggaataggtt ccatggcagc agcagttgta
     6361 gggtttatcc actttgactt tatcttgatg ctaagtgtcc aaacaacgat aactgtcttg
     6421 ctgcttttat gggtttttgt caaaacaaga ttcaaagata agcgtgtcga atgacaagtt
     6481 taagcgattt atgcgacaat gaatgtgaaa aaaatgaaaa ataaagtagt ttttgaaaaa
     6541 tttctgaaaa aattaaactt cttagttgat tcttttcttt tttagtatta acgtaatagg
     6601 gtagtttttt taaggaggaa aatcatgtta gagaaaactt tatacaatca attattttca
     6661 cgttctttct cgctccctgt cgaagtaaat tattgggacg gtacaacgaa acaatacgga
     6721 gatacggaca ctcctcccca aatcaaaatc aatatccatg aagaaatccc aatgaaagag
     6781 attacaagta acgcatcttt ggcactagga gaagcctata tggatcatcg aatcgagatc
     6841 gagggaagta tccaagcatt gatcaacgat gcttatcagc aagcaaacag ctttttacga
     6901 ggaaaagatt atctaaaatg gctgccaaag aaagaaaaac atacgaaaca aaaaaacaaa
     6961 gaagatatcc atgcgcatta tgacttaggt aacgactttt ataaactttg gctagatcca
     7021 actttgactt attcttgtgc ttatttcaat acacctgaag atacgttgga acaagcacaa
     7081 atcaataaag tccatcatat cttagacaaa ctctttatca aagaaggcga aacgttgctt
     7141 gatatcggtt gtggctgggg aacattgatg ttcactgcta ccaaagagta taatgtcaag
     7201 gcaactggga tcacactaag tgaagaacaa tacgatttga ttaccaaaag aataaaagaa
     7261 gaacatttag aagataaatg ccgtgtatta ttaatggatt accgcgaact aaaaggcgaa
     7321 acgtttgatc atatcacaag tgtaggtatg ttcgaacatg taggttctga aaatcttgaa
     7381 ggttatttca aagtggtaaa agatttattg aaaccaaaag gaacagcttt gatccatgga
     7441 atcagccgac aacaaggcgg tgcgacaaat gcttggatca ataaatatat tttccctggc
     7501 ggttatgtcc ctggtgttac tgaattagtt gataatatta caaaaaacga tttgcaactg
     7561 attgatttgg aaagcttacg tcgtgactac caattgacat tagaacattg gacaaagaat
     7621 tttcatcaag tccaagatca agtcacgaaa gaaatgggtg attccttcta tcgaatgtgg
     7681 gatctatatt tacaagcttg tgcagcttca tttgaatcaa gtaatatcga tgtgattcaa
     7741 tatttgcttg ttcaacctgg aaacaatgac atcccaatgc atcgtgcata attgaggcaa
     7801 aagtactgtt taaagactat ttaaaaagaa gctaagtttt atgatgctcc agaagtgaac
     7861 ttttttgtct aacttctagg attgtctcta aagcttagtt tctttttctt tatattttca
     7921 taataaaagt ttggttcttt aatttttaaa catgacagaa aattttttct tcgttatact
     7981 tgtaatagaa tactatttta taacaaaggg gatcgaatca atgaaaaaaa ctgttattta
     8041 tactagttta tttgcagctt tgtttttagc tgcttgtcaa tcaaatacca atcaaggcac
     8101 atctgggaat acgtcttcca gtagcgaaca gcgctcttca caggtatcgg actcctcaac
     8161 aaaagcaagc acatcttcgt ctagccagac aaaaagttct agtgaagcaa gtactcagtc
     8221 agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc caagataaat acccagatac
     8281 tgcaattact agtttggaat tagatagtga ttggggatct tacttctaca agatagaagg
     8341 tgtcgatgat caaaaagaat acgaagcaag aattgatgct caaaatgaaa aaatggagac
     8401 agagaatcca gaaactctag atcgagatga acaaaatggt caaaagaaaa aagaagatgg
     8461 tctggatgtt gataaattga tcacgattga ggaagcagca aaaatcgccg tcgacaaagt
     8521 aggaagcggt acggcaacag attgggattt ggataaagat ttaggtacta cttattggga
     8581 agtcaaagta aaagacggca atcaaagtac atcagtcaag atcaatagcc aaacaggcga
     8641 agtactgtca actgaacaag atgattaaga atttcttcgg aaaacaagag ttgatttttc
     8701 ttttagtcat gatacactag acaaaataac ttgtttgaag gagcgattta cttgagttta
     8761 gaaacgacct ttgccaatca tatctttgcc aatcctttga tgaatgcatc tggtgtccac
     8821 tgcatgacta cccaggaatt agatgaactg gctcattcag aagcaggagc atttatcact
     8881 aagagctgta cgatcaatga acgaaaagga aatcccgaac cacgctattt tgatgttcct
     8941 ttagggagta tcaattctat gggacttcca aacttaggtt tttcttatta tctagagtat
     9001 gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac cgttattttt ttccattgcc
     9061 gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa tagaaaaaag tgggtttaat
     9121 gggatcactg aattaaattt atcttgtccc aatgtgcctg gaaaaccaca actagcttac
     9181 gattttgagg ccacttatga aacactgaaa gaagtattca gcatcttttc taagccgcta
     9241 ggaatcaaat tgcctcctta ttttgatttt gctcattttg atcagatggc tgatatcttg
     9301 aatcagtttc cattgaccta tgtcaatgct atcaacagtg tgggcaatgg tttgtatatc
     9361 gatacagaac aagaagcagt agtcatcaaa ccaaaagaag ggttcggcgg cattggcgga
     9421 gagtatatca agccgactgc tttggcgaat gttcgcgctt tttatacacg tttgaaacca
     9481 gaaatccaaa tcattggtac aggtgggatt cggacaggac aagatgcatt tgaacatctg
     9541 ctatgtggcg caagcatgtt acagattggt accgagcttc ataaagaagg gccggaaatt
     9601 ttttctagaa tcataaaaga attaacgcag attatgtcag aaaaaggata tacgtcaatt
     9661 gacgaattta aaggcaaatt acgcaccatt tcatagcaaa gagacgaagg tcatgattga
     9721 tcttcgtctt tttttataaa aaacactcgt ctgttcattc ctgtgcaagc gtactcattg
     9781 tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa ggaggataat atgaatgatg
     9841 caacagaatt agcaaaagag cttaaagaaa aagaatttag ttttcaagaa ctagttacgg
     9901 atatacagaa aaaaataaag aagcaaaatc atgaattgaa tgcgtttgtc gcgcttgaac
     9961 cattcgagag taattcccac gagctattga ttccccagtc agaaaaaggg ccattggctg
    10021 gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa gggatggcta gctacttcag
    10081 gatctcgttt atttgaaaca caccgagctt ctcatacatc taattatgtg cggcaagcag
    10141 aagcgatagg tctagttcct tttggacaaa ccaatgcgcc agagtttggt ttcaaaaata
    10201 ttacagaccc agtcatctat ggcccagcaa gaaacccttg gaaccttgaa tgtacaccgg
    10261 gcggatcaag tggaggagct gctgctgcag tttcatcagg aatcgttcct ttagctggtg
    10321 ctagtgatgg cggtggttct attagaatac ccgcttcgtt ttgcggattg attgggctga
    10381 aaccttcgcg agggacgatg ccagttggtc catatgcttg gagaggatgg caaggagctg
    10441 ctattgattt cggcttgaca gtttctatga gagacacgga ggctttattt tatgggatga
    10501 gaagtatcca ttccggtgcg ccatatcaag tatcgccagt tgagtggcaa acacatccaa
    10561 gaaaaaaacg gttgaagata gctttttgtg ttgattcacc gatccactca cagattagtg
    10621 aagaggcagt acttgctgta aaaaaagctg tagatttcct tggaaaagaa gggcatgatt
    10681 tgacagagat tccttaccca ctagatggtc gtaaactgat cacgtcttat tatcagatga
    10741 atggcgcaga aacagcagca atgatccgct cgattgaaac aggcatccag cgagctgtca
    10801 gaaaagaaga acttgaaccc atttcttgga ctttgttcca atatggtcag aagctctctg
    10861 ccgctactta catcgattct ctgcatgtat gggatgaagc agcaattgtc atggaaaacc
    10921 tacatcaaga atacgatcta ttcctttcac caacgactgc atttaccgcc cctaaaatca
    10981 gcgaagattt gcaaagtgat gcgataagag cacagatgga acacatcagt gattgttctg
    11041 aagtagaagg tttagacgtt gtttcttcca tgtttgagga gagcttgaag atcacacctt
    11101 atacacagtt ggctaatctg actggacaac cagcaatcag cttgcctact catttgacaa
    11161 aagaaaacat gcctctagga atccaattta tggctgccag aggaagagaa gatttgctat
    11221 ttcaaatcgg ctatctattt gaagcaaatc atcagttcca tttaccaaat ccatggaaat
    11281 agcagaaaca aggagaagaa gaatgaagaa aaaaagattg tttgctctaa taactagtgc
    11341 cttttttatt ttaagcgctt gcggtacagc tgccgctaat caggaagata acagctggag
    11401 taatgtagaa aaaaagaaag aattagtagt agcgacttct ggcacactgt ttcccgcatc
    11461 ttattataat gatcaaaatg aattagttgg ttatgatgta gatttggcaa aagaggtggc
    11521 taaacggtta aatgtcaaaa tctcctttaa agaatacaac gtggatggac aaatcacttc
    11581 tgtttcaaaa agagaatcag attttgctgc gaacgatttt ggtatcacaa aagaaagaga
    11641 aaaaaaattc tccctttcag agactttcaa atattcattt gacagtatga tcgtacgaaa
    11701 aaaagatgat tcaggaatcc actcacttga agatcttaaa gggaaaaaag cagctggcga
    11761 acccaatact agctatatgc gtttagcgga aaaacacgga gctaaattag tcacatatga
    11821 caatgccacg aatgatcagt atttaagcga tgtagcaaat ggtcgaacag atgttattct
    11881 aaatgattat tatctgcaga aaatggccgt atctgcttta ccagatatcc ctgtaaaaat
    11941 actggagaac gtttatttca atgaaaacga aagtggtttt ttattgaaag aaggaaatga
    12001 tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg aaagaagatg ggacgacaaa
    12061 gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc aaaccgaaag aaacgatggc
    12121 tgagtcggtg agtgagtgat gtactttcct ctaattgatt tttccctcat gtggacttca
    12181 cttcctttcg tactgcaagg cttggtatac acattaggga ttggcttcgt gtcgtttctt
    12241 ttaggaaatc tggtagggtt gcttttgaca gttttaggtc ttttggattg gctgcctctg
    12301 aatgtattta ttcgttttta tttatcgttc tttagaggca ttcccgcact agtcctgctg
    12361 tttctgttat attttgggtt accttatcaa ttaagtgcct taacggcttc agtcatctgc
    12421 tttacgatta ccagcagtgc atttattggt gaaatctatc gaggatcact agcaggcgtt
    12481 tcttcaggtc agtgggacgc tggtttagct tctggttttt ctttctttgg ggtattgaaa
    12541 tatatcgttt tgccgcaagc ttttcgaatc tcagtaccgg cactcagtaa cgtagctatg
    12601 gatctagtga aaggtacttc gttagcagca acaatcacag tgccagaaat atttcaaaaa
    12661 gcaaagatca taggcggtcg gacattcgat tatttttctc tctatatttt agttgcactg
    12721 atttattggg tcatttgtat cgggatcgaa aaagtgcaac agtatttaga aaaacgttct
    12781 atgcatcagt caatctgaaa aatagaaatg gtgctagcgt ggctggcacc atttctattt
    12841 tttgtttctt gtatattctg cctagtattt taaaaccatt tcatgtaaaa tgtaaatcga
    12901 aaatatgttc ggaggtagaa aacatgaaga ccccgctaac catcgaaata gaatcctcgt
    12961 tataccaata ttgcatcgag caaggcggct tggttgtaga agaagtcacg atgcctgatg
    13021 accaaggaat tgtagatacg cttagctgct tgacaaaatt tgatggaagc cgagaatggc
    13081 gatgctatga gctgaaagtg acaaaagcag attttcgctc tacagccaaa ctgtcatttg
    13141 ttggacatta taattatttt gttttaccaa gtaaactata tgaagaagta aaaactgaaa
    13201 tccctacagg aataggtgtt ttagtgtatc gtccgtacac ggttgaagag gagatgcctg
    13261 cctctggtac atttctgatt gcgaaaaaag cagcaaagaa agagcttgct gtaccggaag
    13321 aagctttgac aaaccgcttc atggcttctt tattcaggga agtaagaaaa gcaaagcaaa
    13381 tggagcgagg cgtaaaatat tttccaacag atcaattgta caaagaattg aaaagacgtt
    13441 cagaaaatca agatccattt tctaacgaac gatattatga acggttttta gaggaaatag
    13501 ctagtcaggc aatcaatgag ttgcaagaag aagttatcgc gcttcagcat gattatgaat
    13561 atttgaggca acaacagcag atccgtcggt tgcctacaga gccattggag tgaaaaatat
    13621 gtactatcct tatttaagag gaaaacaatt tgacctatta gcattaaaag aagcactgtc
    13681 gcgaggattg ctctccaata aaatccaacc agtgatcgaa ccagtacgtg attccgctac
    13741 gcttaaaaat gtgatcgaat tatttcaaaa aaagcaccat cgaatcgctg tgatccaaaa
    13801 tccccaagta ggacaattca aattattcga tcagcatgtg cacagttgga cagtcaaaga
    13861 aaatagctct gtcgtccctg cacagatctt aacgccagaa aatctcagtg aagtactgga
    13921 ttcacctcca gcgtttcttg ttttcgatgg acagcactac ccaaaagata cagaggtgtg
    13981 gaaacagttg gcaggagttg attcgaaatt tttgatacca gatactagtc gctttcgcat
    14041 ctggctgccc gaaaacaaaa ttgtgatccg tgactctttt caaacgagaa agcatgttga
    14101 aagttatgca gataaaacag atgacttttt tagtgatgac tatctttttt tccacgcaga
    14161 cggatatatt ggattttctg atttcacgat cgaaggtagc cgttatttcg ataaagggtt
    14221 ccctagccga gcgcttgcta tccatctaac gtatattgat gcttacggca atatacgcgt
    14281 gaaacatttt gtctctgaca gtaacgactc tgctaaagac caagcattga agtttcttga
    14341 agcaggagat aaaatgaaaa aatggatcat gcgtcaccat catcaactct tgattacttc
    14401 aggaatgatt gaattattgg ctctttacca gcaacaaaaa ttccctggac tgggagtgtt
    14461 gaaaaagtgg tcacttatgc atcatttgga acttattagt cacctgctag atcatccaaa
    14521 agattggctt aaatattatt caaaagttca ggaactatat gaagtgatcc aatgattaga
    14581 taatgtaaat gaaaaaggaa tagaaaagag gaaactggat gtatattcgg caaacaagga
    14641 aagaagaagt agaagaagtg gtagaaatca ttaatgccgc agcggatttc attgcttcgc
    14701 aaggctctcc tcaatggcaa aacgggcaga aaccaacaaa agaaacgatt ttgaacgata
    14761 ttgaaagaaa agaaagctat gtattaatag tggaagatca aattgctgga acagctgcat
    14821 tagtctcaag cgtggatccc gtttacacaa aaatagatgg tagttggaaa gaatcaactg
    14881 gtccttattt atcgattcat cgtgtcgctt tagcagaaag tactcgagga aaaaaactag
    14941 caaaaccgtt cttagaacat ttgttgacga ttgcagccag caaaaatatc caagatatcc
    15001 gtatcgatac ttatccagct aatgaaccga tggaaaagac catctattct gctggattca
    15061 cttatcaagg gatgattgaa tttccttttg aacacggcga aagaaaagca tatcaaataa
    15121 tcatcaattg actataaaat catctgagca aagataaaga cattaacact actgaaaaaa
    15181 acaatcatat gatagccaag aggttgtaac agaagtggcc agcttcaaaa aacaagaaag
    15241 aatttccgaa aatgcttctc aaatttttgt ggaattttag cgtattttac gaaatagctg
    15301 ctttctgaaa ctcccttcat cgagaggtcg tgacatagct tttgtcacga cctctcggct
    15361 tatcctacga gtattattcg atacatttat atcaataatc ctttttttat tttatctgca
    15421 gcttcttgga acgctccatc gtttgacacg actaaaagtg aggggatagc tttcaaacgt
    15481 ttcaactgtg ctaaatcttc tacataaacc gccagtctgg ctgaaatctg ttcagatgaa
    15541 tctccacgtt ttttcaggcg cgattgcaat gtttctttag agatcgtaat aaagatagga
    15601 cggactaccg tcccgaaata ctcatataaa tgccaaaaac catttgctgt caaaacggcg
    15661 taacaatttc ctactgtcag tttcttttta atttctgctt tactggaacc atatttatgt
    15721 tgagcatatt ggtcccactc tgcaaactca tttcccttga tcatctgatt gaatgtattg
    15781 tcagaaacaa aataataatc ctcttgatct ttttccccag gtcttggtga tcgattcgtg
    15841 taagtaatga tcttttgttc cggctgaaaa atagcttctg cgagtgaagt ttttccagaa
    15901 ccagaaggac cgataaatac atagcaataa ttcattgtca tttctccttt gatgattgaa
    15961 caagtgaaaa agctttggaa aatatttcca aagcttttaa aagtaacttt gcttttttgt
    16021 atattatacc agcaagccag tcacaatagc acttaaaaag ctgactaaag tcgctgttag
    16081 caaaattttc aatccgtgtt ttgcgacaag atttcctttt tcttcattta atcccttcat
    16141 cgcaccagaa atgatcccga tagaagagaa gttggcaaat gaaacgagga agacagatat
    16201 aattgctgtt gtacgctcag taaaatggaa attaccattt gctaattctg tcatagcaac
    16261 aaattcattt gtaaccagtt tagtcgccat gatactaccg gcatccactg cttctttcca
    16321 tgggattccg ctgatgaagg caagaggggc aaagatgtaa cctaggatct cttggaaagt
    16381 gatgccgaat atcccgtgga agatagcatt gatcatggca atcaaagcaa caaaaccgat
    16441 aagcatagca gcaaccgtga tcgccacatg gaaaccatca agaatgtatt ctcccaacat
    16501 ttggaaaaat gtctgttctt tgttttcttc aatgatcagc tcatcttctt tttcttctaa
    16561 tacataggga tttacaattg aagccagaat ataaccgcca aataagttca aaacaagggc
    16621 agtgatcaca tatttagaat cgatcagtgc catataagat ccgacgatcg acatagaaac
    16681 tgtagacata gccgatacac tcatggtgaa caaacgtttc tcagatagga agggtaattc
    16741 cttttttatg gaaataaaaa cttccgattg tcctaaaata gcagaagcta ctccattata
    16801 agattccaat ttgcccatcc cgttgatttt acttaatcct agaccaacag ctttcataaa
    16861 taatggaaga atcttgatat agcgtagaat accgataata gcagaaataa atacaattgg
    16921 catcaatacg gaaagaaaga aaggtgcact tcctttattt gctacaccgg caaaaacaaa
    16981 gtcaacacct tgcccagcaa aagcaagaag atgatcaaac atttttgcca atacagaaac
    17041 aaccgctgta ccaaaagttg tacgtaataa tacgaaacca agaacaagct gtaaaacgaa
    17101 catcacaatt agtggtttca atttgattgc ttttttgtta ctgctgatca aaaaagcaag
    17161 ccctaatgtg acaaataaac caataatacc taataaataa ctcaaataat cactcctatt
    17221 ccaaattccg ttttatttta cctgttttgc aaataaaata ctaatcttta gtgaaatttt
    17281 cattactttt ttagagtgaa acgcattcat tttccattag aaaataaagc gaacaaaata
    17341 aaaggtttaa aaagtgtaac gtcttagtaa agtctataaa aaaacgaaac tatcgattaa
    17401 gctaatagtt tcgttttcaa catttataag taaacttttt ctattggtaa tatagatttt
    17461 cggaagggta gacaggtgcg caggtaatat cgattcctag ttttttcaat gtttgttcat
    17521 catttttatt gaccatcaca gtagagtggg cttgtgctcc ctcaagttca gctagtttat
    17581 cataagcaac ttgagcgatt ggattcgtta ctgcactgat tgataaagcg atcaagactt
    17641 cattgatgct tagtgcatcc aaagaggaat gaagtgtctt tgatttcaat ccttgtattg
    17701 tttcaagaac taatggtgac aataaaggaa tgtcatctgc gatatgggct aaatgtttta
    17761 ctgcatttaa gataactgcc gctgacgcat ccatcaatga acttgtacgc ccggtaatga
    17821 tgacttcatc tggtaattcg attgcaatca cagcagaagg atcttttgta ggactttgcg
    17881 cttgaatctt atctgcatag tcatgggcag ggactaccac gtttcggtct tcaggacgta
    17941 aaccgacttc ttccataatc agtttgattc gattaactgc ttcttcgtcg atcaatcctt
    18001 ttttgaagtc gcattctgtt tggaaataac gacggatgat ttcttgttta gaggcttctt
    18061 ggacaacggt atcatccacg atcccaaatc ctacacgatt cacacccatg tcagtaggag
    18121 attgataaac agattcttta ccagtaattt tttcaataat acgtttgatt acaggaaatg
    18181 tctcaacatc ccgattatag ttcacagcta ctttattgta ggcatcaaag tggaaggaat
    18241 cgatcatatt gacatctttt agatcgactg tggctgcttc ataagcaatg ttcagcggat
    18301 gtttcaacgg aacattccat actgggaaag tttcgaactt ggagtaacca gctgcatgtc
    18361 ctttttggct ttcatgatac agttggttca aggaagtagc gagctttcca cttcctgggc
    18421 caggagctgt cactacaacg attggtttag ttgtttcaat atactcattt tttccaaaac
    18481 catcttctga gacgattttt tctacgttga ctggatagtc ttcgatttct gagtgtttat
    18541 agaccttgat gtttcgtctt tctagtttat tgataaagac tttcgtggca ggctgtccac
    18601 tatagcgagt gataacgaca ctgttgatta ataagccata accacgtaat tcatcgatta
    18661 accgcaagat atccatatca taagtaatcc cataatcacc acggatctta ttacgttcaa
    18721 tatctccagc atagacgcaa atcagtattt cagcttgatc tttcaatttt tgcagcaatt
    18781 tgattttcgc atcttcttca aatcctggaa gtacacgttt cgcatgcttg tcgtcaacta
    18841 gcttcccacc aaattctaaa tataatttgt catagtggtt cactcgttcc aaaatatacg
    18901 ctgactgctc ttcaatatat ttttctgaat caaaaccaat ttttttcact aggttccctc
    18961 cttaagtact aaagcatttt ttcatttttt tgaggattcg tcaactggaa gagcgaaatt
    19021 cctcaaaaaa acaaagaaaa tggtttaaac caacttgtct agatagttat tcattggtat
    19081 gatagttttt gataaggaag gtgctacatg aaaaaaagac agaaaaagaa aaacgcatat
    19141 aaacactata tccgttcgat ttttaccggt tatgaaagaa tgcttgaaga tcccgaattg
    19201 gaacaattga cgtttactta tctaaacgaa gaaacgcagc taactcgtga tgagcatcag
    19261 cgcattcatt tcacaacaag agatctgcct agtaaataaa aaataagata aaggtcatcg
    19321 gattcgattc tgtcctatca gatggaaaga ctagttgatc gaaaaaaagg ctgtaccaaa
    19381 ttttggtgca gcctgtttta tggagcattg cccgctcttt tttataacaa ttttttacag
    19441 aaaatggtac tattgaagta ttaataagtg aaaaacagat gagtaagagg aggcaagtag
    19501 tatgaaagag ccagatacaa atgcaaatta tgagccagac gaactagagg agacgaatgc
    19561 ggatcaggat acaggacaag aatcgtcttc tttttacgat atcaaagaaa aagcaagcat
    19621 gaatctttcc caattattag aagacttaca ggcttttgaa aaagctgtcc gcgaagaaga
    19681 tatccctgag atctaccgtt tatacaatgg ccgattgaat gaagaattaa aaagaagctc
    19741 aaatgaaaat cacgagatcg atcaattgct gatgcgtaag atccatgatc gttttttaca
    19801 ggaatttcct tttatggaac aagtagaaaa catctcgcca acgatgagct attacaaaat
    19861 cggcacttat taccatgatc ggcccacggt cggtattgat gcaagtctgc cagaaatttt
    19921 tgttttgcct aagatcgatg aagagtggga gaaatattcc caaccggagt caacggacta
    19981 tgacaaaaaa atcaatgagc tagacgcaaa ggtgatcact gctcagacag aaattgaacg
    20041 tttagatgaa caaataaaag aaatcaatcg acaaatgact gatttgaacg acaataaagg
    20101 attcttgaat cgtaaaaaaa tcgaggaaga aattcaagaa ttagagaaga agaagcaagt
    20161 actatctaat gaaaaattag gctggcttcc ttatattgag acgcctgaaa caatccagca
    20221 gcaaaaagaa gcattgaagc aagaagcaag agcagaccag cttcgtgcag ccatcgtaga
    20281 aaaagaacaa aggcaaatca gacgctattt cggtagcaaa gagggattcg gtcaagcaat
    20341 ccatgaattc ttgatgaatt atcttggcaa tgagaatcct aataatcaat ctaatgaagg
    20401 aggttccgag tatgaatgaa cacgatgaag cagaatggac aaaaaatgaa gaacaaacag
    20461 aagatcatga agaaacgaac acttcattgg aagaacaaac aagtaatcct ctggatgaca
    20521 cagaagaaat ccctatgcta gaggaaacaa aaatacacga aaaagaaaaa gtaactccga
    20581 cgaatacgaa tactgcagaa aacacccatg cttacgaaat aactgaaaat cccgggtatt
    20641 tagaaggaaa agagcaagat catcaagata tcgtcagttt gattgaaaca gcggaagcag
    20701 aattagcgga tttacgtatg agaaaagatt tgatcgaatc agattttcca caattattag
    20761 aatcatatga tcgttttata ttgaatgaag aaccaatctc cacgatcgga aagacaagcc
    20821 tgatcgaata cttcacgtat gaattactga aaccgttgaa tgatattggt ctggaacggt
    20881 caaattcagc ttatgacaca tggaaaacaa gacatttttc gatcaattat acgttgaatg
    20941 gacaaaacga attagtcttt tcctttgtat taccgaccat cgatcaacga taccaagtgg
    21001 aatcgatgag tctcctaaac gtatcaccag agacaatgga aatcaatgtc caagatgacc
    21061 gggtgctttc tttgatccga cactggtcag tggatcgagt attctctgca gggcagatca
    21121 cgatattcaa tcacaaattg aatcaattat tagcccatgc aagaacactt ggttttaccg
    21181 ttaatcagac attactagac aatacgaagc cacttcgttt gaatcttcag agcgaatttg
    21241 aattgacgaa tgaagtattg gatgatattt ttatcgtggc aatgaaaaat ccatcctacg
    21301 atatggaaaa gatcaacgaa actacttatc aagtacgatt agataaagga cagtctttaa
    21361 cgataacaac aaacgaaaaa gatcaaacag tcttgtcgat ctcatctgga gactacccac
    21421 gatctgtcat tgatttcttt atcaattacg aattcttggt cccattaatg gtgagaaagt
    21481 cctgattgga taagttggat taccagatgt cattcagata attctgttcc aaaggacttg
    21541 cggcagttat ccagaataat tgtcacaagt cttttctgta tgtactaaat ggacgtgaat
    21601 aacttgctga tgaaggaggg atttcattag gaatgtccac aaataaaata gcacagctta
    21661 gcttattgtc tgctgcttgt gtagcaggta ggatcgcttt tcaatttatt ccgaatttcc
    21721 agccaatgac tgctattttt ttatttatag tactttactt aagcttaaaa gatgcgttaa
    21781 ttgtcatgag tctttctatt gcgatcagca gtttttattt tggtgttgga ccatgggtca
    21841 tcggccaatg gatcagctat actgttgttc tgagtttgtt ttcaatcgtc tgcttgagaa
    21901 aaacagtgca aaggaatcta tggttaaagg gagtctgttt ttttctggcg ggcatggttt
    21961 acggaatagg tatgaccgtt tttgatacgc tgttatatcg tttgcctcaa ccttggatct
    22021 attaccttca aggggtgtcg tttgatttga tgcacagtat aggcaatgtt gtgttctttc
    22081 ttgtttttct gccagtcgtc aaacgttttt acaatcattc aggaggaaaa aatgaaaaaa
    22141 ataatttata gtttgcttgc aatgagtgtc agtatactca ttttgacaag ttgcagtaca
    22201 acctatacac aatcggcttc caaccaaaag gaggaagtaa aaacatcgca aaaagcaaca
    22261 atcacgttac aagaaaatgg tcaaaacttt tcggaaaaag aagtgttctt caaaaaaggc
    22321 gatgatttac tgagtatttt gaaacgaaat tttgaagtca aagaagataa cggcttcatc
    22381 acttcgcttg aagggcactc acaggatgag aaaaatcaac tctattggat gtttactgtg
    22441 gacgggaaaa gtgctactac tggtgccaaa gagatcaaat tgaatgatgg acaatcggtc
    22501 attttcaatt tgtctaaact ataagtttca taaaaaactg ttaaagggcg aatattgcca
    22561 taattcagtg agttcagttg atgaaagaag gaaaataaca tggaaaattt taaaaaaagc
    22621 ggaatgtttt ccgtaattgc tgctctaggg gctaatattc tagttgctat cagcaaattt
    22681 gtcggctatg caatcagtgg cagtgccgcc atgctaaacg aaagcatcca cagtatcgtt
    22741 gattgcagca atcagatttt gctgttattc ggtgataaac aagccaataa aggacagagc
    22801 gagttgcatc aatttggtga aggacgagca aaatactttt tcagtacaat cgtcgcaatg
    22861 atgcttttct tcggcggtgg ggcacttggg gtgatggaag cttttgaaaa gttgacgcat
    22921 ccatcccatg aagtgggtaa tccgatcatt gttatagcaa tactgttatt tggtttggta
    22981 atcgaaggaa gttcgttacg cgtggcaatg aaagaaatca aagaattgaa tactgaaaaa
    23041 ctttccacga tgcgcttttt gcgcgaaagt cgacacagtg aaatactgat tatttttacg
    23101 gaagacttgt gtgctgtaat cggtttggtc ttggctttag caggaacaat attgacttat
    23161 gcaaccggga ttgctgcatt tgatgcgatc agcggattgc tgatcggttt cttgctgatg
    23221 ggagccgcca ttttcctagc aaaagaattt tatagtctga tcatcggtga aagcgtgaca
    23281 gcaagcgatt tatcaaaaat caagttagct tttgaacgtc ctgagatcag tcggctgatc
    23341 gatataaaaa cagttcattt aagtccaacg gagattttag ttgcagcaaa agcagatatc
    23401 gttggtaaca aagagaatga agcttactcg gtcatcaatg atattgaaaa aaatatgcgt
    23461 cagtctcttc ctgacaagaa gatgtatata tacattgaaa cagataaata tgacccaaat
    23521 tattctcgta aataaaacgt ttattcatga attgaagcaa aaatgagaaa aatataatct
    23581 tgtttttaaa taaaacggct acaatttagc gaatttatgt tacaatgagt ccgctgttta
    23641 tttgttgtaa ttaaaggaga tattttaatg aacaaaaaga aaagtgcgcc atggcttcaa
    23701 gctttgcatg cagtgatgcc actttgtata agctatatac cagtaggatt agcttgcgga
    23761 gtattgttgc aaaaagttgg atttgatcct ctcttatcag gactgttatc gattctggtc
    23821 ttttccggtg gcgcgcagtt tttagttgca tctatgctta cgacgcaagc atcatttgca
    23881 acgacattat tgatggtttt ctttttagaa ttacgctata cattattagg agcaagtctt
    23941 gccggtttta tgaaaaaaga aaagcggacg tttttggctg tcttttctca atcactgaat
    24001 gatgaaaact atgcggtgaa ctacttaaag ttttcaactg acccttcctg gaataaaaga
    24061 aaggctttat atgtcaattg gttctcaatg actgcatggg ccggtagcaa tatgatcggt
    24121 aattttttcg gctcggtgat tcgagtagat gctgaccttg tccattttgc tttgacggcc
    24181 atgttcattt tcatgtttat catgcagatg aaaagcgcac tactgatctt tacaggttta
    24241 ttctcaggcg tattaggggt cgtattcatg gtattattcc aaaatacttt cggattgatt
    24301 gcagcaacag tcattgcttc atttgccgga tttatgctgg agaaggcatt caaaaaagaa
    24361 aaagctaaga aactaagaga ccgcggtaaa gatgtcaatg agccgctctt caacttcccg
    24421 gaacaggagg ccaatcacca tgactaaact atatttgcta cttttagttg cttgtctgtt
    24481 catcgtggca tatatcccgc gcttgttccc gatgctttat tttactcatc gaaaagtgcc
    24541 atcctggttc agtgactgga tgaaatatgt accggtggca ttatttgcgg cgttagcttt
    24601 taaagatgtt ttcattactc atgaacatct ggatattgct tggaatatca aaatagctgc
    24661 aatgattcta gtagcaggcg tggcttacaa aacacgttcg atggcgttgt cagttttgac
    24721 aggacttgcg tctgtctttt tgctgtctat gctttaaact gttttatttt attaaaaaca
    24781 gagattgcga cataagttgt tcaaactgat ctatccgaac tgcatttgca acagtcaatt
    24841 ctggatgcaa gtttattcgt agggataaaa aagattagtg ttggcttatg atgcaagctc
    24901 ttttttattt taggaattag agagggattt gtccttctat gattttttgc tataataggg
    24961 aagatgttta ttttatgaaa gaatagttga gggaatttaa atgaataaaa aattgatgca
    25021 aggaacattt tggctaacct ttgctaatct tctatgtaaa gttttagggg tagtctattt
    25081 gattccctgg ctaagtatga tggggaacaa tcaagatggt atgcttgcta cgacattgta
    25141 taatgttggc tatcttcctt atggattgtt cctgatgctt ggtacagtcg gatttccaaa
    25201 tgcgattgca aaaaaagtag ctgtagccac aaaagaagga gataacgctg cttgtcggct
    25261 gatttttaga agtacgatca atatcatgtt tgtcatcggt atcgcctctg ctgcactgat
    25321 gtatttattt gctcctttac tagccggaat cagtccgatt gctaacgtta ataatgggat
    25381 actagctatc agaagtttat gcccatcttt gattgctatc ccaattctta gtgcaatgag
    25441 aggatatttc caaggaaaaa atgatctgcg gccttatgga acttctttga ttatcgaaca
    25501 ggctgtgcga gtgatcgtta tcttggctgg tacttattac ttgcgcgtat tgactgacgg
    25561 aaccatatta gaagctgtat tgatcagtac agtcgcttct ttcttcggtg ggttagctgc
    25621 gattatccat atgtatatcg tcggacgcag aaaagacttc ttcgaactta aagatttttt
    25681 gatttccagc cgttatttcg aaagagaaaa ccgatctgcc tctgtctcta tcattcggga
    25741 aacactaccg tttatttttg tcggctcagt cattactatc gttcaaatga tcgaccaagt
    25801 aacgatgaaa ccactgcttc actttttccg tccagagatc gcagatcagc aactggaatt
    25861 cttattcagc cgtgcttctg tcaatccaaa taaattgaca ttgatcctga tctccatggt
    25921 aggaacagta gctataagca gcttgccaat attaagcacg atgaagaaaa aagatcggat
    25981 acaaatcgaa aaaacagtag gagatagttt ttcgattgcg ttattgattc ttcttccttc
    26041 attgactgga atgtctttat tagctggacc actatacaca ttgttttttg gctatgatcc
    26101 tgaaagtgtc ggatatttcc aaatggcttt gctagcttct ttgtttttct ctttattcac
    26161 gatcctatct acgatgcttc aatctttgaa tcaccatcgt tttgcgatcc gattaactgt
    26221 agaagcaatt atcctgaaag tcatcttcca agtaatcgga ttaggattag ttggcggata
    26281 cgggatgagc ttatcaaatg gcttagcatt cggtattgtc tttgttcgcg gctatcactt
    26341 tatgtgcaaa gaataccgaa tagcaccttt agcaaagatc agcaattttt tcttaaaaac
    26401 tttccgctcc accctgatta tgcttgcagt atgttttgcc gttttctttt tgctgaatca
    26461 gcgattgtca atggaatcaa aaagctatgc aatgatttat tgtgtggctg taggaagtat
    26521 tggcggctta gtatttttat tttctcaatt cggaaaaaat gggtttcgaa tgttgaaaaa
    26581 tgttaaacat catagcagaa gcaaagaata ggttaactaa tcgttttttg ctgtcacttg
    26641 aaaaacggca actcgtatga ttacgcttgt cgtttttcta ttttccaatt ttagtttcat
    26701 atctaatctt acttatgata tagttataag gtctggaaaa attctttgaa acgaggaaat
    26761 taaacacatg aaacttgcag tagttacaga tagttcggca tatctgccgg aacgtatcaa
    26821 gaaccatccc gacttattcg ttattccaat ccctttgatt atggatggga aaatttataa
    26881 cgaaggaatc gatatcgaag cggatgaata ttatggactt ttaaaaaaca gtaaagattt
    26941 tcctactact tcacaacctg tcgtagggga agttttgggt ttatatgagg aattgaaaga
    27001 gaaagggtat gacacgattt taagtatcca tctttcttca gggatttctg gctttgtcaa
    27061 cacattattt gcgatgaaag atgacatcag cggagtaacg gtcattcctt atgactctaa
    27121 gatcactagt atgccgatgg gacacatggt agaagctgcc ttagacttaa atgatgaagg
    27181 tcagtccctt gatgaaatac ttgcacatat cgatcgaatc cgagataata cctacgctta
    27241 tctgattgta gatgatttga acaatttagt acgaggagga cgtttgacaa atggtgcagc
    27301 gctgattggc agcttattaa aaatcaaacc gatcctgaca ttttctgaag ggaaaattgt
    27361 tttattcgaa aaaatccgtt caagtaaaaa agcatttgct cgagctgaag aaattattgg
    27421 tagaagaaat aacgaaatac aaccgccagt caaactttac gtgatacatg caaataattt
    27481 agaagtagcg attgcggaga aagagaaatt gcagaaaaaa tatccaaatg cagaaatcga
    27541 aattggtcat ttcggaccag tcattggtac acatttaggt gaaaaagcca tcggcattgc
    27601 catttcagcg caataattcc ttttattcaa aaaacatacc aaaaatattc caacatcatc
    27661 ttggactttc tacatgttac taatgagcgt gtaaaagaac gagatggtgt ttttatttct
    27721 atcaatgaag ctctttttct ttgcaatcct cacttcaatc ctctataatg tcgcatatag
    27781 tttagtaaat gagtaaacta ctaatttact tatttactaa aaataaaagg atgaggagtt
    27841 aaaataatgg aaataccaac aaatttaaaa cataaaccag taatcgttgt agaagactat
    27901 gataaagttg atggaagaaa tgcattaaat acggatgcaa aagggctttc actgggcctt
    27961 gctcagtgga atgatcgtgg aaaagtcgat atctcaggca aggtatggcg acatactgga
    28021 gaaaaatggt cacgacagtc ggaagaatta ccaatcacac gtattttaga tttagcgatc
    28081 ttagctgcac aaggaagttt atacttccaa gatgcttatc gttatgaaaa attttatgat
    28141 ccagaaaatc cagtcgtaga catcattgga ttacaaggga accgaatgac ggtagaagta
    28201 gataccaaaa atccaaagat cgatgaagac atcattttgt attacgatac actacaaaaa
    28261 gacggagaac tgattgggga acgattccgt attttaaaac gtcttttaga tgagctagga
    28321 tattaataga cagagatgat caaaagggga agagaagcat ggagaatttc tcactaacag
    28381 aaaaccgaac cttttcacgg ctagaaaagc aaatgatctg gaagaaaccg aaaagccatc
    28441 ggacaagtgc agaagaatgg cggatcgcct ccgaaatcaa agggaattgg caagatcctg
    28501 aaatgaaaat cagtaacgta cttttggaag gagatgccgg gtcggggaag acacaattag
    28561 ccaaagcact atctgctgat ctgcaacttc cctatacaaa agtgacctgt tttgcagata
    28621 tggacaaatc agatgttttc ggagccttat tacctgtagt agattctaat aaggaacaag
    28681 accaagaatt actagaagct atttaccaaa cagatacact tgaagctgta ctgacactga
    28741 tccagaacca ttacggcatt gatccttttt ctgctaaaga aaaattagca gagctagttc
    28801 aaaggatcga agctgattat ccagatgcaa tccattacag ctattaccct tctgaaatcg
    28861 ttcgagcgat tgaaaaagga tatttattag agattcaaga gccgactgtc atccgagatg
    28921 cctctgttct tgtggcactt aactcagcgc tcgaaccaaa tgggatgttg aatttaccga
    28981 caggaatcat tcgtcgccat ccagattgcg tcattgtgat cactacaaat cgaaattacc
    29041 aaggaaatcg cccattaaat gaatctttaa gagatcggat gcaacatgcg gaaaaaatgg
    29101 atcttcctgc cttagaagtc atggcagaac gtgcgatggc gaaaactatg atccaaaaac
    29161 aagaacttct cttaaagatg gcagagatta tccgtttgtt ggatgaaact gcaaaagcta
    29221 acgccatcaa aggtgtagca ggaatgcgtt cttattttta ttgggcaaat acctataagc
    29281 aaggacaaga tttactccag tcgatttatc caaaagtttt gtataaatta tccactgatt
    29341 cagatgaatt ggcaattctt gaacaagctt tgtctgacag tggattgcta ctggaacttc
    29401 aggacatatt gagaaaagaa aaatggggtc atcctcaatc tgagcataca aaaggaagaa
    29461 ccattagcgc cgaagaagca aatgaacgaa acatcactga aaatgctgaa gaaattctgc
    29521 gcttagatga aaagaaatcg ttgtctgctg aagaaccaaa tgagggagaa gagaaacaag
    29581 aagaaacaat agaaaaaaac gagattcctc ctcaaatgca aaaagaacgc agtagcgata
    29641 tcgaaggaaa aaatcaaaaa gaacaacaaa caggagatga ttctcaagaa atgtctgctt
    29701 ctgacatgga agcacatgat aaggaaatca agaagcaact gaataaagaa gcgcgacaaa
    29761 tcatgaagga aacgattcat gaaaaagaag gtctcatcgt tcaccgacca gctttccaag
    29821 gaaaaacgcc ggaagcacgt gagctacaca tgcaagtaat gccaatagta gaatcactta
    29881 gccggcaaat tttagagtta ctggataatg aacaaacaga gacgtaccaa aaaggaaaat
    29941 acgaaggtca gcggttcaat gcaagcaaag tagcatatgg tgatttgaga aattttgaca
    30001 aaaagaaccc gccacatgag caaccttctt tagcggtagc tgtacggatc gatgaatctg
    30061 ggtcaatgat acgggatgat cggatcgaag cggcaaaaaa agcagcgatt gccattgccg
    30121 aattttctaa gaaagtcgat atcccattgt tgatttacgg agatacagca gaccgttcgt
    30181 caagagaaaa gacttctttg ttttcttata aagaatttga agacggattt caatggttaa
    30241 atgaaaaatt agtcactatg aaaccaaggc aaaacaatcg tgatggtgct gcacttcgtt
    30301 tagcagcaga aaaattaaac agacaatccg caacaaccaa actgttgctt aatattagtg
    30361 acggtcagcc aaaagcgttg ccggattata caggcaaaaa agcaaaagaa gatatccagt
    30421 ctgttttgaa agaatatgaa cgtcaaggaa tcctatttgt ctccgcagct attggccaag
    30481 acaaagaaga aatcaagtcg atctacggtg aaagtcgttt tgtagatatt actgacttga
    30541 atgaatttcc caagcaaatg attcaactga ttgcccgcta tctatgataa aataaagctc
    30601 aacgaacgca cttagcagat tcgttgagct tttcgtttct agttaccggt aacaaggata
    30661 cttctaaaat agaatcggtt ataatcaaga gggaccgtta aaggagtgaa acgatatgat
    30721 acaagaacaa aaatggtgga aagaagcagt aggctatcaa atctatcctg ctagtttcaa
    30781 agatagcaat ggcgatggtc aaggagacat caatgggatc cgtgaaaaac ttaattattt
    30841 gaaagatctt ggtatcggct ttatctggat caatccgatc tatcaatctc catttgtcga
    30901 taatggttat gacgtaagtg actatcaaga tatagaagag agattcggaa cgatggaaga
    30961 ttttgattta ttgctaaaag aagcacatga attagggatc aaagtgatta tggatcttgt
    31021 catcaaccat agttcggatc agcatcaatg gtttgaagaa tcgaaaaaat ctaaagaaag
    31081 cccgtatcgc gattattaca tttgggtcga cggggtagat ggcaaagaac cgaataattg
    31141 gacatcgatt ttcggcggtt ctgcttggga gtattctcat gaaactggac agtattatct
    31201 gcatgttttt gcaaaagaac aaccagactt aaattgggaa agcgagaaat tgaaagaaga
    31261 actattcaat atgatccgat ggtggttgga taaagggata gatggatttc gtttagatgc
    31321 gatttctcat gtaaaaaaag atgaatattc agtaaaagcc acagagaacc ctttctcacc
    31381 ctttcaaaat gtctcaggaa tcgaagaaca tttgaccgat ttgaaacatg tttttgaaga
    31441 gtacgatatc atgactgtcg gagaagcaag tggtgtcact gcagaagaag gaccacaatg
    31501 ggtagggaaa gacggttatt tcgatatgat attcgaattt gatcatatcc atatctggca
    31561 gcaagaaaaa gaagggcaat tagatgtcct taaattgaaa cttgcattaa gcgcttggca
    31621 aacttcattg gatggtatcg gatggaacgc tttatatatg gaaaaccatg atgttcctcg
    31681 tgccgtttca gtgtttggag atactcgtcc cgatttttgg gctatgtctg caaaagcaat
    31741 cgctatgatg tatttctttt tgcaaggtac gccatttatt tatcaaggac aggaaatcgg
    31801 aatgacgaat atgccctttg aatcgatcga tcaagttgat gcagtagatt cgaaaagact
    31861 ttataaaagg ctgcttgcgg aaggtaagac aagagaagaa gcattggata tcattcgtga
    31921 aacaacgaga gacaacagca ggacacccat gcaatggact tcggaacaat atgctggttt
    31981 ttctacacat gaaccttggc tgatcactaa tccaaatacc aaaacgatca atgtagaaca
    32041 acaagaatat gaaccagagt cggtcctgca attctataag aacatgatcc gcattagaca
    32101 aaccaataaa ggtctgatat acggttctta taaagaatat cttcatgaac atccacaact
    32161 ttatgtctat gaaagatatt tagaagatga acaatatctt attatggtaa acttaacaga
    32221 atcacttgct gactatgaac ttccaaaaga agcagatcag tcctggacat tactcttgtc
    32281 aaattcctct agcggagaat ttgaagctaa aggcatacta gcaccttatg aagctcggtt
    32341 atataaaaca aacaagtaaa acttcctcgt taaagttcat tagttggact ttgcgaggaa
    32401 gtttttcaga ttgctctgtc aattactcat ttcaataatt cgctctagga ccaccgatat
    32461 atttaggacg agagcgaagg gctgtcacgt gagcttgtcc aagggttttc aaacgaggtc
    32521 tgacaggtac ttggacatgt ttgatatgca taccgattga tgtgtcaccg atatcgatac
    32581 cggcttgtcc aactacgtgt tccacttcga caggatcatt gaactggtca aaagcagcaa
    32641 cagaacaagc acctccagca tgtagtgcag gaacaacaga gacaatttcg aaattttttg
    32701 cttctgccac tgttcgttct actactaatg ctcggttcaa atgttcacaa ccttggacag
    32761 ctagcgcaat ttctttagga tccaacaact cttttaacgt acggatgatc cattgaccaa
    32821 cttccgcact ggaatttttt ccaatatgtc ctccaacgac ttcgcttgtg ctgcatccta
    32881 aaacaaaaag atcacctttt ttcaagtgtg cctcagccaa tatgtcatta actatttcag
    32941 tcaattggtc ttttaattct ttttctgaca acttcatttt ctaaaacctt ctttttcaat
    33001 taatattgct tccgtgcttg aatacgttga agacttgcag ttataggaaa ggcaagtccc
    33061 attccaatca gattttggaa gatgtttcct ggtatagaag ccactccagc cggccaatca
    33121 tataaaatcc aaccggcgat accatagccg atgatcataa ctaagcttcc taataaaagc
    33181 cctaatcccc acatacgagt agaagatttg ctgaaagaac cagcaacata tccttgtaac
    33241 ccgtggatca ctaatgaaaa aactgcccac tgcggatatc ctgaaatcaa atcgatcaat
    33301 agaccactgg aagcaccaac aactaatcca cccgttggac cataaagaaa agcagcggta
    33361 tagatcccgg cctcgcataa tgtcacaaat ccattcgtag ccggtacagg gatcaaaatt
    33421 gttaatgaaa gggcaactgt caacgcaatc agcatagcat agatcgttaa ttgcttagtt
    33481 ttcatttctc attcctcctt tttgaatacc gccagaccag acacttccgg tatgatcgtt
    33541 catcagcacg ccattagaaa tacaatgggc aacaaatttt ttactttctg ctactgcttt
    33601 ggtaaaatct gcccctaaca caagattcgc tgttattgca gaagaaaagg cacaaccggc
    33661 cccgtttact gttgtagtgt cgattttttt atgagaaaat acctcataat gatcaattga
    33721 atagagaaga tccacagctt catctccagc catccttgtg ccgcctttga tcacaatgtt
    33781 ttttgttcct gaagcagtga gttctttagc gagatggatc atttctgtta acgaagaggg
    33841 aagagcttga ccagaaagta aagcagcttc tgccaaatta ggcgtaatca tcgtaacaag
    33901 tggaaaaagt tcttcgatga gctgcgaaat atacaattga ttgatcacag cttcagtttc
    33961 tttgaatgcc aaaacagggt ctaaaatgat tgggatattt tgttttgttt ttatgaagtc
    34021 tcgaacaacc atgattgctt cacttgaatt caataaccca attttgatac catctaatga
    34081 agtcatttta tcaatcgaaa ctaactgtcg tttaagcaat tccaaagata tagattccag
    34141 cataaatcgc tcattaatat ctagtgcccc tatagaagtc aaggcgctta gtccgaatag
    34201 accaaaattc tcaaaagttt ttaaatctgt ttggattcct ccaccagcaa atggatcaga
    34261 accgccaatt gtcaagattc ttttcataac attttcctcc atgaataaga gtataacgaa
    34321 attttcaaaa aagaaaaaca gccaattggc atatttttat ctcatccaat ttaaaaaaac
    34381 aaaaagaaaa gaaagaccaa aatggatctt tctttcctta aatagttagg acttttgtga
    34441 ttttaattct ttctcgattt gaagccgttg cactttcatt gtagctgttc gcgggattgc
    34501 atcaaaatca cggatgatag ggacgttcaa gcgaggaagt tcatggactt gctcccacca
    34561 tcgattccaa tccatttctt tatcaggagc taaagcaata atcggttgtg gagaatgatt
    34621 tttatccctt acaatcacta cttctgccaa aaaatctaac gaatctaata aaaagtcttc
    34681 aatagctaat gtactattga tcgtttcgat caaatccact tgccgatctt tcaaaaatag
    34741 gtggccatgc ttatccataa aaccgtaatc tccgctatcc caccaatcgc cataaacatt
    34801 ttcctggaac cgtgcatctt ccttgtaata agtcaaagcc cgtcctttag acagtaattg
    34861 tatatgacca tctgtgtttt caggtaggac attcccaact gaatctgtaa tccgagcgct
    34921 tgtcatgtct tccagtccaa cgcccatatc tcttgcatca cttgttttca aactctctag
    34981 tgtatgagcc ttaagaatca ttggtccgca ttcactttgg ccatatactt gaagaaatac
    35041 cgcatcctgt gccatcgacg ttcgcaaaaa tgtcttcatt gtctggttgt ttatagcatc
    35101 aaaagtggag tgatagtatc ggatacccga aaaagcttct ggatgctcct tagcagtaaa
    35161 acgccactga acaaagttat tcggatgggt ctctagtgca attggccggt gagcttccaa
    35221 catatgaaca acttttgaac tttgtgcgtt tgctaaaggc atcataggaa atcccatgga
    35281 catcaaagaa gagataccaa tattgaatct ggaatgcact ggagagatgt gaaaagcgat
    35341 taatttcttt tccgaaattt ttgtgaaaac tgttttttgc catttcgtcc gccatcccat
    35401 agaatgagca gaatgacaaa taagtttagg gataccagtt gtaccagaag tatgggtcat
    35461 ataagaaatt tcatttttgt ctaaaaatga ttgagaaaca gacaaagcag gttgttccat
    35521 taaataaaga ataggaa
//
LOCUS       DADVXV010000019        35519 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.019, whole genome shotgun sequence.
ACCESSION   DADVXV010000019 DADVXV010000000
VERSION     DADVXV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.019"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(154..780)
                     /locus_tag="KB969_000906"
     CDS             complement(154..780)
                     /locus_tag="KB969_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868914.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(1075..1410)
                     /locus_tag="KB969_000907"
     CDS             complement(1075..1410)
                     /locus_tag="KB969_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6868915.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(1397..1681)
                     /locus_tag="KB969_000908"
     CDS             complement(1397..1681)
                     /locus_tag="KB969_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6868916.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(1737..3260)
                     /locus_tag="KB969_000909"
     CDS             complement(1737..3260)
                     /locus_tag="KB969_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6868917.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(3253..4428)
                     /locus_tag="KB969_000910"
     CDS             complement(3253..4428)
                     /locus_tag="KB969_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6868918.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(4432..4617)
                     /locus_tag="KB969_000911"
     CDS             complement(4432..4617)
                     /locus_tag="KB969_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868919.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(4583..6277)
                     /locus_tag="KB969_000912"
     CDS             complement(4583..6277)
                     /locus_tag="KB969_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6868920.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(6274..6747)
                     /locus_tag="KB969_000913"
     CDS             complement(6274..6747)
                     /locus_tag="KB969_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBB6868921.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(6816..6971)
                     /locus_tag="KB969_000914"
     CDS             complement(6816..6971)
                     /locus_tag="KB969_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBB6868922.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(7105..7485)
                     /locus_tag="KB969_000915"
     CDS             complement(7105..7485)
                     /locus_tag="KB969_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6868923.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(7489..7704)
                     /locus_tag="KB969_000916"
     CDS             complement(7489..7704)
                     /locus_tag="KB969_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868924.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(7707..8114)
                     /locus_tag="KB969_000917"
     CDS             complement(7707..8114)
                     /locus_tag="KB969_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBB6868925.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(8380..9855)
                     /locus_tag="KB969_000918"
     CDS             complement(8380..9855)
                     /locus_tag="KB969_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBB6868926.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(9845..10693)
                     /locus_tag="KB969_000919"
     CDS             complement(9845..10693)
                     /locus_tag="KB969_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBB6868927.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(10730..11092)
                     /locus_tag="KB969_000920"
     CDS             complement(10730..11092)
                     /locus_tag="KB969_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868928.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(11093..11251)
                     /locus_tag="KB969_000921"
     CDS             complement(11093..11251)
                     /locus_tag="KB969_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868929.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            complement(11392..12016)
                     /locus_tag="KB969_000922"
                     /pseudo
     CDS             complement(11392..12016)
                     /locus_tag="KB969_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(12013..12324)
                     /locus_tag="KB969_000923"
     CDS             complement(12013..12324)
                     /locus_tag="KB969_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868930.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(12368..12661)
                     /locus_tag="KB969_000924"
     CDS             complement(12368..12661)
                     /locus_tag="KB969_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868931.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            12855..13502
                     /locus_tag="KB969_000925"
     CDS             12855..13502
                     /locus_tag="KB969_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6868932.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            13563..14708
                     /locus_tag="KB969_000926"
     CDS             13563..14708
                     /locus_tag="KB969_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6868933.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(14789..15094)
                     /locus_tag="KB969_000927"
     CDS             complement(14789..15094)
                     /locus_tag="KB969_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBB6868934.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(15119..15550)
                     /gene="ruvX"
                     /locus_tag="KB969_000928"
     CDS             complement(15119..15550)
                     /gene="ruvX"
                     /locus_tag="KB969_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBB6868935.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(15547..15813)
                     /locus_tag="KB969_000929"
     CDS             complement(15547..15813)
                     /locus_tag="KB969_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBB6868936.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(16068..16793)
                     /locus_tag="KB969_000930"
     CDS             complement(16068..16793)
                     /locus_tag="KB969_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBB6868937.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(17154..17224)
                     /locus_tag="KB969_000931"
     tRNA            complement(17154..17224)
                     /locus_tag="KB969_000931"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17190..17192),aa:Gly,seq:ccc)
     gene            17341..18093
                     /locus_tag="KB969_000932"
     CDS             17341..18093
                     /locus_tag="KB969_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6868938.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            18109..18588
                     /locus_tag="KB969_000933"
     CDS             18109..18588
                     /locus_tag="KB969_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBB6868939.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(18839..20419)
                     /locus_tag="KB969_000934"
     CDS             complement(18839..20419)
                     /locus_tag="KB969_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBB6868940.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(20412..21155)
                     /locus_tag="KB969_000935"
     CDS             complement(20412..21155)
                     /locus_tag="KB969_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6868941.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(21331..22107)
                     /locus_tag="KB969_000936"
     CDS             complement(21331..22107)
                     /locus_tag="KB969_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6868942.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(22355..23191)
                     /locus_tag="KB969_000937"
     CDS             complement(22355..23191)
                     /locus_tag="KB969_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBB6868943.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(23202..24131)
                     /locus_tag="KB969_000938"
     CDS             complement(23202..24131)
                     /locus_tag="KB969_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBB6868944.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            24323..24676
                     /locus_tag="KB969_000939"
     CDS             24323..24676
                     /locus_tag="KB969_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBB6868945.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(24750..25406)
                     /locus_tag="KB969_000940"
     CDS             complement(24750..25406)
                     /locus_tag="KB969_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6868946.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            25632..27566
                     /locus_tag="KB969_000941"
     CDS             25632..27566
                     /locus_tag="KB969_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6868947.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(27652..28875)
                     /locus_tag="KB969_000942"
     CDS             complement(27652..28875)
                     /locus_tag="KB969_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6868948.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(28869..30767)
                     /locus_tag="KB969_000943"
     CDS             complement(28869..30767)
                     /locus_tag="KB969_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBB6868949.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(30761..31879)
                     /locus_tag="KB969_000944"
     CDS             complement(30761..31879)
                     /locus_tag="KB969_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBB6868950.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(31962..32795)
                     /locus_tag="KB969_000945"
     CDS             complement(31962..32795)
                     /locus_tag="KB969_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6868951.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(32788..33705)
                     /locus_tag="KB969_000946"
     CDS             complement(32788..33705)
                     /locus_tag="KB969_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868952.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(33932..35056)
                     /locus_tag="KB969_000947"
     CDS             complement(33932..35056)
                     /locus_tag="KB969_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6868953.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            35239..>35519
                     /locus_tag="KB969_000948"
     CDS             35239..>35519
                     /locus_tag="KB969_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6868954.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLA"
BASE COUNT        10689 a         7158 c         5777 g        11895 t
ORIGIN      
        1 tgaatgagaa acccatatca aagaactata aaggttatca aaacagcgtt tatgactaaa
       61 tgaattagag ttatctatca ctatttttca agcgatttaa accaaatggc atacaatatg
      121 gcatacaaaa acttcaataa gccgtggggg tttttaaatt tcttcttgtt ctttaaaatc
      181 aatgagtgga gctacataat ttgaatccac tttttcaaac gtcacttttt gcatcgacga
      241 atgttttctt tcccaagata acgtaaatag atttgactct ggacttataa agtctacttc
      301 accttctagt attactttct tatgcaaata ttcctctaat aaatatagac ttgctaaagc
      361 atacaacaca ttttccaaat ttgcttcctt ataatttgaa gaacgaccat gttttactct
      421 gttatatatt ttccaccaat ctggtgtatc ttcaggccac ccatctccaa aaggttttag
      481 tgaagtcaat gttaaagaat tcataaccct aacaccatta tccaaacaca ttaattcgct
      541 agatttaata acagctttaa aatcagttat gcttttattg ctactgctat caaatccgca
      601 aagttctttg aaaataatct cacactccga accaatcgct agtagtagtt tttgatattc
      661 aatagagaat gttttgaaat tattctcatc gagcatcaca aaatctgtgg tattaataaa
      721 ctcattttct aaatgtagat aatacttcca ataaaaattt gtaaactctg ctttgtccat
      781 taaatcacct cttttgaatt ataacaaaaa aaacacgtcc acaacagacg tgttctttga
      841 tttctacaca atcagcttgc caaaaccatc caatcagtcc tagcatgcct gtattaaaat
      901 tgaacgttca tcatctatca tctttcttag tccagcatgt ttgcaaccac acctacaatt
      961 ttcagtccaa caatagattt cgactagcta agtcttgcaa aattcaggca gctaaccctt
     1021 catttactac cttaattata ctaaataccc acaacgttta caagtgtaat cattctaaga
     1081 aatctgttta gctatgatcg ttgtataatc tttaaacgcc gttccttcat tgattgaaat
     1141 aattttataa ctcttgtttt tccaagctac tttcatatcg tttgttagtt cataatcttg
     1201 atcgtatcga ataataaacg tcaacgttcc ttcaagaatg gtacctacac tagcaagcac
     1261 gtcttttagc atttgtgaac gcacattagc ccaacattca aatacagttt cttcactatc
     1321 caccatctgc ccatcttcat cttttacccg ttttgtcttt ttaaacttga ctctctcagt
     1381 caattcattt acattcttaa tgattggcat aataagcacc tctcatttgt tgtactaatg
     1441 cttgtaccgt tactggtatc cgttcgctgc tggcttcttg acggttcaaa taccaatgtt
     1501 gagtaagtaa tgacaccgcc aaatcaaatt gctgataatt atccatatct ttatccgttg
     1561 cgctactatc aatagcactt tttatatatt cgcctgctgt atcaatcaat tgttgaataa
     1621 agtcatcatc aatagtgtga tcgatccgca tacttttttt tatgctatcc aaaattacca
     1681 ttttatctct cctaatgaaa aaaaggcagt gggataaacc gccgcccaat atttttctat
     1741 acttttggtg ttacaactgg cgtaaactca atatacactg aagcattttg atcaattttc
     1801 ttataatcgt tgcgaacgat cactgcaagt ccttgtgagt agtaatcgaa tttttcccat
     1861 tgagtcgtta cttgatttct acgagcaaca aagatagatt gtgcaatatc ccccataatc
     1921 atagggaatg ttccagcttt aggattggca aacaatgtat ctgcaatcaa tactactggc
     1981 ataccgaata atgatttacc actaggtgct gtcacatcgg gttgtaaaat gtaacgtcca
     2041 tctgaatctt tcaatgtatc taggtggtaa tatccgcttt ggtttagaat taccatttta
     2101 tttaatgctg ggtctaatgc cacattgtat agttgtttca aatcgtccaa cgtagcagcc
     2161 gttttcttag tgaatgtttt taataaatcc atgatatgct tattgtcagt gttttctacc
     2221 aatttcgcta actgatcttt gacctcttgt acaatattca ctgctgaatc ttccacaacc
     2281 tcatttgata aggcaatctt accagcacga gtttctactt tataatcaac tgaagtaaac
     2341 atttcagcgt caatatcacc aatttcagca agttcagctt ttgttgctaa cactgcttgt
     2401 tggttagttg ctactggata tttaccttgt ccatttgata ctgtttttac tgttgcatat
     2461 tgagctaagt tataatttga acgtttcaaa tcaaagactt caccgattac ttcttcggga
     2521 acaactgccg ctgcatttac agtagtgact ccatcacgca cttcgccttg tgaacggata
     2581 tattcttcat acccacgcaa ttctgttttt tcgttatcga ttaaagtttt ttccatgtta
     2641 ttactctcct tttgtgcttt agaagtggat tctaagctat tgtttgtttg ttttgcttgg
     2701 ttgttactca taaacgattc gtaagaacgc ttatttactt ggacatttga tgaatcataa
     2761 gcgggaacgg tcacgacact aatttcatta agtgctttga ttttatctat tgatcgttca
     2821 attgtgccat cttctttttt gtcgaatgaa tctaatccaa gcacgaaccc aaaggacata
     2881 gaatcaacaa ccccttttga gatattctca tacacatcat ttgaataggt cgtgtcggtt
     2941 agctctgctt caaaatgtaa tcctgtatca tcgacattca atttcaacgt acctgctttg
     3001 acactagcta gtggctttga ataatcgtgt ccatataata agaacacatt tgataaatcc
     3061 acctctttta atgcttcggg tgtaatcact tctacaaagc cgcctaaatc ttttgacggt
     3121 tgcccgaatt tcaacgcata gcctgaaata gttttgccgt ctgttggttg tttttcattt
     3181 tctttctcta ctttgggaga atcggctgtt agctcagctt cttctgtcag ccgtttttcc
     3241 ttttcttctt cattattcaa ctggtgtaac tccttcctgt tcttttaatt gatatttctc
     3301 caacgtatct aaatacgtaa agttcaaact tgctagtaaa cgatcgccac catccatggg
     3361 gggtagcccc attttcgacc gcccctcatt aatcgtgaga agtgaccctt tgacctgatc
     3421 caatacattt tttacttttg tttcaggatc agtctctagt aactgatcgg aattaaagcg
     3481 gatattggtt tcaagtttcg tatctaattc actcacaaac acattaaagt aatgaatcag
     3541 cgtactttgg atatactgga gattactttg aacggtgcta gaatgttcat tttcaacgcc
     3601 taaacgctca atcggtacac caaacgcctt ggcaatttgt tttgtgttcc aatcattgga
     3661 attgataagc ttcaaaacat cggtgtttat ttctaatgtt ttgtagtcca ttgtttcatc
     3721 aagaatgatc gttctaagag cattatctcc actacttgaa ccgttggctt cttcaaactt
     3781 ttcacgaatt gcgttctttg ctgatccgtc taaatctgac ttatgaacct tcaaaatacc
     3841 tgacccactg acaccacgag taaagaaatt gtgcaatgtg cggttgccag cttgttgaat
     3901 tttcagttca tcacgtaacg cataaagtgg tggtaatcct gttaaaccat cttgggtgaa
     3961 atatttgaag tgcaaaatat cgctagactt cacacgtctt tttttatcac caatctgata
     4021 agacaacgta ccattatcta attgagtaac cgttacactt gagttaggta ataagtgaat
     4081 ttcttctacc ttttcaccgt tgcgtttaat ctctgcaaag ctattaccgt ttagcaacat
     4141 attgaccgcc aaagcaaact ttaaatgcca accatccatt tctgaattag gtttctcgtt
     4201 tagtaacttc accagttcat tatcagcttg tggcatattg tttttgacca attgaatcgg
     4261 acttgaagca atatcactag caataattcg aacggctgca aacacatcac tatttcttaa
     4321 tgcacgaacg cttgtaaagc tggtggtgta atcatccgat tggattgata ccacatgttg
     4381 taggaaagga tctcccgttg tattttgtct cgctttaaaa aatgccatct tttaacctcc
     4441 cttctgttct gtatttagca tgaccgctac cccaataagc actatgccca gcgctaacaa
     4501 gccatagtag acatttgtta gtaaggtgat agcaaccaac acacacacca atccaagaag
     4561 taaaagaacg gtatgaatgt aattagaaag aaaattcttc acttgtataa aattcattgt
     4621 ctgctttcgc tccttccgtt gtggtgaagt aatccattgc aaacacatag gcattgatta
     4681 atgcagctat tggatcaatt ttgttactgt tctttgattt attaatctga atgccgttgt
     4741 tatccgtttt taaaatagcg ttgttcactg catgggtgag aatcgtattt ttattgtgaa
     4801 taacgttgcc ttcataaact tgttctctaa aagttcgggt cggaacgttt agagtaatcg
     4861 ttccttgtct tacttctaac attgggtagt tggctttttc agctttactg ataagcgaat
     4921 tagcgttata cgggtcataa caaatcccca tacattccaa atcattttct tgaatcaaat
     4981 cttgaataaa ctgaaatact tggtcatagt ccacgattcc actttctaat tgagtaatgg
     5041 aacactcacc agctttttct agttctcgat aaggcaaacc gtcgcgcttt tctttgtctt
     5101 gaagcccata tttggtggct acaaagctat gtgaatcaca ataaagttcg ccgttatcta
     5161 gcggtacgat ccatgaaacg ctagttaaat catctgtttt agataaatcc actccgatat
     5221 aaacgggctt gcctgtaata tcttgtggtt ctacttcggt tgcctgccag tcttcagcaa
     5281 tcatatagct gtcctcactc gcttgtctcc ataaattgaa gtttttcacc aatacagaat
     5341 taaggttatt ttgtttcaaa gcaaggttca catcatcttg aatggttgga atcattactt
     5401 ttttgatttc ttcactttca aaaatcggat tggctttgat ccatttctct tgatcgtgaa
     5461 tttcttcggg atcgtccaat tcccatatcg ctataaagta cctgtcggct tgttcttcgc
     5521 cttttagcac acgatctaac aataagtatt cctcgtacat aggaacgttt aaatcaagcc
     5581 cagcggtact aataacacac aataagccgt tcttttgttg ggtcattcct gacttaatga
     5641 cgttgtacgt tttacgagtt tttgcttcgt gccactcgtc aagaattgcg gttgttggtg
     5701 caaacccatc tagcgtgctg gtttcactag ccagtgccat agcgaacgaa ttagagggca
     5761 agtgctgaat cttagagttc ataattttca gttgtggtct taaaaactta ctagacttga
     5821 ccacgtttct aagtgaatta gacagcatat catagcccaa tttagcttgt ttcaaagcgt
     5881 tacttacaaa caatacttgc cttgcttctg ctggttcttg ttccataatc aacgcattgg
     5941 cagccatgcc acttgcgata tacgttttcc cattcttacg gctcatactg gtaaacgctc
     6001 gattgaatcg cctgtaattc ccttctttag tacgccagcc ataaagactg cctagaatga
     6061 atttttgaaa tcctaacatc ttgattgctt taccgtccgt agatggtagc aactcaatga
     6121 atttaatcgc tttggtggct tgttcttcat cgaacacata agggaagcta tctgacttag
     6181 aacgctccaa atcgcttata tgacgctcac acgcttggat aattttcttg ggtgcaatca
     6241 gcttacctga taggactttc tcaatgtaat cattcatgaa ttcatcaact ctttgaacgg
     6301 gtcttcgggt tcatcatttt taaccttgtt caaagctagt tttgatcgtg attctaaggt
     6361 catacctagt gaggtggctt gttttttcaa atcactcata gcttgtgatt gaacccgaac
     6421 cgctggattg gctttcttta ctccgttttc gcatgtgata aacgtacctg attttcttat
     6481 ctcggcttcg gctgttttca ttcgagcaaa ggctaaacaa taggctacca atgaaccata
     6541 atctgcttca ctcaatggat aatctttttt taatgttggt acgatacgat tccattcact
     6601 tctagcgctc gctgccatcc agtcaggggg cgtgatattt attaatggtt gctgcttgaa
     6661 caattcttct ctagcgtcca cacggattgc tttttcttca cttgatatat tgccttttgt
     6721 atcgtgtaat attttagggt gtcccatgtt gtcctccttt cagacaaaag aaaaaggaac
     6781 gtaagcaatt aagctcacat tccttcgttt ttcgatcaga atttttcttt atctaattta
     6841 tctatataaa tgatttttcc gttctgcatt tgaatggtca cttgaccaaa atgaggtaac
     6901 tcaatggtgc gctgtttccc tgttttatca gtaataacaa ttgtattttt caataaatct
     6961 cctactttca ttatatactt tttcacttgt gattacaagt gtaatcgtta tttgtaatta
     7021 cccttatgcc ttttcacaac ggttatttgt accaaaatga gtaggcatcg attgtcagta
     7081 agtttcacac tatgccccct taactcaaag ggtactcttt tctcgtcttt gtctttcatt
     7141 ggctgtcttg gaattatggt gtgcatggca taaagaacga aaattagttt catctaaccg
     7201 tctattccaa tcatctttta gttcaatttt gtgatctaca acatcagctt tccttatcaa
     7261 gccttcttct aggcaatcct cacatactgg atgatttaac cgatacaagt atgaagcctt
     7321 tcgccatgtt ctactttgat agaattgaaa atatttacct tcgctttgct ttctttcttc
     7381 acgcttaatt gccgtttgct ttgctttatg cttcccacaa tacttctgcc tataatcaat
     7441 caatgtttta catccagcat gattacattg ttttttaact gccatagatt accaaccaaa
     7501 gcgatctcgt tcgtcagaat catcttgttc ccattttgat ttgtattcaa tataaggcga
     7561 aactatcttc aagcacgttc cgtctttaaa attaacttta gtgattttat cttcctcaaa
     7621 actaataaag tctacatctt cttgagtgtt tgaatactca atgtgtttct caccatcgaa
     7681 gtatctaata ctttccatat gcataattat tctacctcca ataaattagt tatcaattca
     7741 tcatctgtta gtagcaaagc caagaactta tcatggatgt ttaaaaacaa attatcctca
     7801 ttcgatgtaa gctctcgttg tctcgctcga tcatataggt taagcagaca attaaattca
     7861 tccattagct cacctgtatc atcatagttg ccactatcta ccaatgatcc cactactagc
     7921 gattgacacc acgctactga ctcctgcagc caatcaggtt cttcttccat tatctttaat
     7981 acttctggat caaatgtgga ataatcttct gttaccaatc ccacactaaa tgccagcgtg
     8041 ttcattagaa accgatccat ttcatctgta tattgaaagt tcggtgcttt gtttgttgaa
     8101 ataatattga gcatttactt tcctccttga ttcgtaacac gtggtaacac ctacgtaaca
     8161 ggtacccgtt accactcaat cccaacgggg acaagggttc tagcgttttg gtaacaggta
     8221 acgggtaaaa tccagtaaca ttattcccca gcatattagc taactatttc aaaagtttta
     8281 aggaaataag gtgttacccc gttaccaaat tgctgtatcc cttggggcag taagggtaaa
     8341 ctagtaacgg gctaggtgtt actgacccgt tactacccgt tactttttgt actttccagc
     8401 tcgattttta ttttcatagg catttgactt attgtaaaat cctcgtcgtt tatttctttt
     8461 tggcagttgc ttccgttccc aaccaggaat actgctaata atcaaggcaa tctttttagt
     8521 ttctgcatct gatcgaccat tcaataaatc ctttgcttgt ttatcaaaaa cagcttccaa
     8581 aatatcagcg gtgagtacgc tatcaactaa ataaaactct tgttgcatag tagctccatt
     8641 atagaaatgc tgtaaatttt tctcattaca tttactgtca ggatagttct gataataaga
     8701 acgtctcgcc cacgctggag cttcttccca tttatacggg atttccattt ccaaatattt
     8761 agtgattgct tctttaattg gattctccat cttggcatcc tcttgatagt cttttgcaat
     8821 ttctaagact tctttatctt catcgggact aaaatagatt cgttgtcctt tatcaaaaag
     8881 cacctttgct tcagctaaca cttgaagaaa atattcatcc tttgttttaa acggattcat
     8941 ctttggctta ttcttacaag gcaaaggata aaaacggcgg tttcctgtat catctttcaa
     9001 atactgccca tcattcgacg ttccaataaa tacacattgc cttgcccaag ctatgacatt
     9061 ccgaccataa ggaggtctaa ttttatcgat cttggcactg atgaagtttt ttatctgttc
     9121 aattttagtt ttgttcattg aagataattc tccaagttca ataattacat tgccttgaag
     9181 ctgcatataa tcatctttct tttcacctag cgaatctaat gaatcggtga aaaaatcatc
     9241 cgtgtaaagt aatgctggaa cggtactctt accaatccct tgcggtccat ccaaaactgg
     9301 aacgatctca aactttattc ctggtttata gatacgtgcg actgatccga ctatccaacg
     9361 ttttgttact tctcgtgtgt aaaggttgtc gtctacccct aaaaggtcaa taaacagtgt
     9421 ttccagtcta ggctgttgat cccatttaac tttttcgata cgttctttta ctgggttgaa
     9481 aacattcttt ctagccacat ttactactgc tttgtgtatt ttgttgtcat caaaaactac
     9541 attgtagttt tcttcaatat atgccgttaa ggcatcctca aaactgtctt cccattctcc
     9601 agcggtacga ttgatccaag gagaatcttt taataggtga atgtatccgc taaattcgtt
     9661 ataagcaatt gttccagcta aattgctatc attggttaaa atcaattctg cattcacaac
     9721 actgttactt ttaatctgat cgtctttatt gcatcttaat cgtgacatcc aggttttcaa
     9781 ttcaatgata ttgtcttcac gctcgctggc ttcgggaaag tctaaaatac tatctaattt
     9841 atgcttatga gccatgagct ttccccctca aatctttttt aatcatcgat cgaataattt
     9901 gattcacttc tttatctttt agcggtggtt cattgtacgc atttgctgta taaatcaatt
     9961 ctgctaaagt ttgattatct acaccgtgcc atagtaacca accgcataac ttagttaaat
    10021 gatcgtttct actaccttcg ccagcgcctt gaacaatcat atctaatttt tttgctgtcc
    10081 ctgtttttgc tacgggtcgg tattgagtct ttatttcttg cggttttttt agcagtaggt
    10141 tcactagcca atcgggagct ggtgcaatat tatttagaga tacgttttca ataggttcat
    10201 atgctctccc aacacttctt gaaataatca tagttggcgc tattggaact cctttagtga
    10261 taatatcaat cccgcttaaa cttttacctt tatcatcacg cccgaagata tcagcaaatg
    10321 cacctgtttc ttgttggata attacaccat caggaatttt aaagaagaaa tggattcctt
    10381 tacctggtgt gatttccgta taagtagaag gaaatggatc atacattgaa gcaagttttt
    10441 tataattctc aacgccgttt cgtgtttcag aatgttgatc taggtcaact accaccattt
    10501 gatgatcttc aagcattaac ccaatatttc tagttgcatc ttccgtccac cattcattaa
    10561 tttgattaga atcgttagtt gcatcattcc aaccactaga gccttttatt ggaattttag
    10621 ttccaggaga taagggataa attgaccatc ccgacttttg taattccgtt gctgcttgat
    10681 aattatttgc caataaacct ctcctccttt ttcaaaatac tggtataaat cattcagaca
    10741 cctccatgag cttcaactgc tcaagttcgt atttcaaccc atcccgaaca aattcagcac
    10801 cttttaattg attctgatac tttacccatg tattaaatgt tttcaccctt gcttcttgca
    10861 tatcagtaat gtttaaccat gcggttaaaa tctgattttt tagctcgttg atttctcgac
    10921 aaattatttt gtgttctgca tgttttttga gtacatacaa aactgttagt ttttcattga
    10981 atgaatttcc aaagtaggtt ttcccgatat tattttctag ttcagcgatc ccttgattaa
    11041 tttcctctaa ttcaaggcta tcgagttggt ttaatagttt tgttttgtac atctacttat
    11101 gccctccagt tcttaattga tagtcgtact cgtcataagc agtgaagaga tataacgcta
    11161 atcctgcaaa gatagctatt tttgcaatta atggtaataa gccgaaaatt ccgccgatta
    11221 aaatgcttcc tataattaag tttcgtttca taatggttcc ctccgatttt ttaatatggt
    11281 ataatcggaa caaagaatat cgggttttat cccaattaag ttgcctttat cctgtccgcc
    11341 aagactgtta tggataaggc tttttctttg ttctcgatca tgttaatgct cctaagttgt
    11401 ctgcaattca gcagaacgat tataaatttt ctcactcact gaaaactgca acccatattt
    11461 ttctttaaca gtcattaatt ctactgtctc atctaaaata ggttcacgat caaccaacat
    11521 ttcaggagtc atatctttct tttttaccat tttggaatga ccataaatag ttgatacagc
    11581 tttattggct atcacattcg ctttaatgta gtctactggt tttggttcag taatagcgtg
    11641 gcttaattta gtcattgctt ctttttggtg ttctttgtct agcatgcgga atacttgaaa
    11701 gccttcaagt cctgtggact ggcgtagttc tttgatgatg tcgaaaatcc agtcttgaaa
    11761 tgcctcggct tcttttttac ggcttttgaa tgccatgcgg taaatatttt ttttcgttga
    11821 tgatgtttac atcttgtgtt ctgcccaatg aatcgatgac cttactagta gtaaccccat
    11881 ctttaggcaa agagtgaatg gctctagtaa cctgtttaag acctaacgct tccgcaacat
    11941 ctttcgccac tgcccaccat tcatcattaa tatcgacaaa tcttataatg tgtccgttcc
    12001 aaatttcagt tttcattcaa cgtcctccag ttcaagccct agcaagctcg ctaacaactc
    12061 aacttgctga tacaaaattt cttgatactc ttcaatagaa agtcgttctt taaactctgc
    12121 ttgtactaaa tcgttcaagc cacgcaatac tccgcttacc gttggttctt gtggtagcaa
    12181 tttttgatag tccatttgtt cgtacaaaca ttcaaacgtt tcttctagcg ctttgccttc
    12241 caagtttgct aattctgccg ctgtgtcttc tgtaagaatt gttgataata ctttttcgat
    12301 tgctttattt tgtgtcgatt ccattattat ttcctcctat taatcccttt gcccccacgg
    12361 cttgcgttta tttttggtat tcttccataa agcgatcaca ttcatcttgt gaaattctta
    12421 cgactccatc aactataatc aactttaaac cgttaggaac atatttctgc atcatagtat
    12481 tgtatgaaac gttcatatac ttagcagctt gtgccttgtt catatatttt ggaaactggt
    12541 actttttttc taataatgaa agtaacgttc cttgagtttg ctctacttgt tgaacaactc
    12601 gatcgtcaat aattttaaaa gctggatcat caagcgtgag tttgtcaatt tttaattcca
    12661 tatttatccc ccctcgttag catacatttc tatacaaaga ttttaaaaaa atgcaagagg
    12721 ctcttgaata catttctata cctcttataa actcaatata ccatcatacc ttttcatttg
    12781 caagaatttt aacatacttt tttgaacttt tatgtttcac acatatttaa atcgtgatat
    12841 agtagagaaa atatatgaat ggtggtgaaa atgtggctag aaaaaaatac cccgaagcag
    12901 tggagacagg acaaagaatt agactggcta gaattgaaaa gggactctca atggaacaac
    12961 ttggaggtaa attatcccca ccggccagta aaggtgccgt tagtaattgg gaaaatggct
    13021 ataatcttcc caataacacc aggcttaaac aactttcaaa ggtattagat gtatccacta
    13081 cctatctatt aaacggatct tatacattaa gagatatgca tatgatgccc gaaattaagc
    13141 gaaatgtgct tgaaaagcaa ttgaaaaaaa ctattgaaaa aaataactct ataattgatt
    13201 ctaatctttc taatgctatc aataacatcg aagaagataa cctgactgtc tcacagaaga
    13261 tttatttaac aaacgcaata aaatatctta aaacaggatc tcgaattgaa tttcctgacg
    13321 ggagtacccc aattgcttat ctcgcagctc ttctaaatac gcttttacga tatgactcat
    13381 taattaatga ttcagaaaaa aatacagatg agaaaaaaga gtatcaagaa ttttatgaaa
    13441 atgatcttct aaaagagttc acagctcttg ttactgagct aaataaacac tattcaaaat
    13501 aataataaac tgcctcctcc aaccgccccc acggcttgct acactatgga gggaaaacta
    13561 ttatggcaac attcaagcaa tatgaaacta aaaaaggtaa attttggctc tatgaagcct
    13621 atcttggaat gaacaaaatg actggcaaac ctgataaggt tcgtagacga ggttacaaaa
    13681 caaaaaaaga agcccagctt gccttgtcac gcttgcaagt ggactacgat aaaaacggta
    13741 ttaaaaaagc gaacaacgaa acgtttaaag aagtttatga cttgtggcta gaaacatata
    13801 aaaccactgt ccgagaagcc accttcatga aaactgaaat caagtttaga aagtggattc
    13861 ttccaaaata tggaaatctt cgtgtgaatg aagtcacggt aaaaaaagcc caacaaattg
    13921 taaatagctg ggctgaaact actgaccaat acaaggtact tcattcaact tctaagcgta
    13981 tttttagcta cgctatcaat cttgggatta ttgagactaa tccactagac aacgtattaa
    14041 tgcctaaaag aaccaccact aagcataaag aaaaggtcaa agtttacagt aaagaacaac
    14101 tgatcacctt gtttgattac ctaaacagca aacctgaaac ttatcgaaac gactttgata
    14161 aaacgttact acgctttctc ttttatagcg gggttaggat cagtgaagcc cttgcattga
    14221 attggtcaga cattgatttt caagaaaata cggtcaccat caataaaaca ctaagccaat
    14281 ccaaaaatgg ctataaaatc agtgatccta aaactgattg tagtgctggg gttcttccac
    14341 tagatgaaag aacaatttct atattaaaaa aatggcagat taatcagcgg aaatatatgc
    14401 tgacacttgg tgtaactgat ccgactatga ttttttgtgg tatctataaa gaactaatca
    14461 cacaccacgc tatttatgca agattgatta ctatttgtga aaaagctatg gttccatttc
    14521 tcggtgtgca tgtagcaaga cacactcatg cttcaatgct cttggacgct ggagctacta
    14581 tggtagaagt tcaaactaga ttacggcata caaaaattag tcagacgatc gattgttacg
    14641 gtcacttggc aaaagaaacg aaagaaaaga ctgttgaaaa attagtacaa cacttaaata
    14701 ttgactagat ggcatacaat atggcataca gtaaaaaata aaaaaaggag aaaccctatc
    14761 atatcaaggt ttctcctagc tttatagtct attcttcttc ttccgccatg aatgtattga
    14821 atacttcttc aatcatgtcc cattctgcgt ctgtttcgat ttgttctaac tcgccttctg
    14881 ttccatcttc gttttcgatg tatgcataag cttgtaattc tacatcttca tcttctgaaa
    14941 caccagcagg atataaaaga acatagttac gtccaaattc ttcttgtccg tcaactgtta
    15001 gtaggatttc atataatgtt tcatttcctt ggtcatccac caatgtgatg tgttcgtgtc
    15061 cttcatggtc gtgggaatgg ttatgttctg tcataagatt acctcttttc ttttattatt
    15121 aaaataattg cttacctgag ccgtctaaat aattttgtaa gatcatcaca gctgctaatt
    15181 tatcgatgac tttttttcgt ttggctcttg aagtatttgc ctgctctact agcatacgtt
    15241 ctgcctgaac agtggttaat cgttcatctt gataatcaac tggcaaggag aatagttctt
    15301 tgatcttttc tccgtatgac atggaagctt ctgcccttgg tccgatggaa ttgttcatat
    15361 ttttaggtaa tccaactaca aaccggtcta cttcatattg tgctactaat tccttcaacc
    15421 gatcaaagcc aaactcttct tctgcttcat tgatccgaat gatctctact ccttgagctg
    15481 tccagccaaa ggggtcactg atagcaacac ctactgtctt agaaccgaca tccaagccca
    15541 ttactctcat aaattcactc catgatttga gaggtagtcc ttgacaatta cttccatgat
    15601 ctcatcgcgt tcgtgacggc gaatcaaatt tcgagcatca cgataacgag gaatgtagga
    15661 cgggtctcca gaaagcaagt agccgacaat ctgattgatt ggattgtagc ctttttcttc
    15721 caaagcccga taaacaatcg ctaatgtttc gctcacttct tttttgcgac tatcgtcaaa
    15781 accaaaacgt acggtttcat ctgtaaaacc catgattcta cacctctttc ccgcaaggta
    15841 attccagctt accttctaca accttatttt actcgaagaa agggaaaact acaaacaaat
    15901 attccaaact tccgaataaa ttaagaaaca ctatttgtat gtttttttcc ttttttctgt
    15961 agctttatca aaagtactct tttcataaag tatacgctat atttctttga atgtatgttt
    16021 ttacacaatt ttttcataat attcataaaa aattcgaata gctgctacta attttttgtt
    16081 tttgttgctt gtcctgtctc ataattgatc gtgtagccat cttgaacatt gtagataaag
    16141 acattgaatt caattttttt gtcttcaatg ctttctgctt ccaattgcac tcccctggct
    16201 accagttcat tcccctcaaa atgaggagtg acacggtagc gtacatgatg atttgtttct
    16261 ttgatatatg ccgcaatatc attttcgtga gcaagcatgt atggagcatt caacgaacgt
    16321 gtccctgtca tcaagttttt aatgttgtta ttttgaccag tcagctggaa accaattaaa
    16381 tggctgcgat tatataacca ttgcccgtca cttaatttct tttgtttcca acctgtcggg
    16441 tcaatataca aaggctctct cttttcagta gggaacaaat cttttccaag catagcattg
    16501 gcttgtccta ctctgttcaa tttatcaata tttgaatagc tttcccatgt tcctttggaa
    16561 aggctaagat cctcttttgt aaattccggc tgattcccat tgatttctat ttcttgatgt
    16621 tttccatcat attctggcac atccgctact tgagaagctt gtggtgtgga atcaaaaata
    16681 gttgtaatct gctgaaagat atctgaatct ttttgtgtgg tggaaacacc gaatgcccct
    16741 gcaatcacag cagcgacgat ccccacgatc gccttggttg tttttttgct catttcttta
    16801 ctcctttact aacagctccc taaatcttaa catatgttcc cctataaata aatactagaa
    16861 agaaatagaa acagcaaaaa ataaaacctg ttttaagatg gcttaaaaat acaaaaaaga
    16921 gacggattcc tcgtctctaa tcagtcacca ctctatctgt aaggtattta ttattattca
    16981 aaaattttct tcatactcaa gacaatacac tgatttcaca accgcttggt aaacggtgcg
    17041 caaaagcttg catctgcggt aataagtcca tccaagttaa aaacataaga agttgttttt
    17101 gcttggctgt tcttattact tgttgcagag cagctttttc acaacctatt ttaagcgggt
    17161 gacgggaatc gaacccgcga catcagcttg ggaagctggg attttaccac taaactacac
    17221 ccgcaataca aaaacagtat acgcctcttt tattccttcc tcaagttttt ttattcttta
    17281 cgcttctggt atgttttgta gtaaaataaa actaatcaat caattattgg agaagatgct
    17341 atgacgggaa aagaattaga tctgttgctg gacacttgtt tactcgctgg gaaaatcatg
    17401 atggaaagca atgcggagat gtatcgggta gaagatacga tgagtcgaat tgctttagct
    17461 tctggaaatt tccgtttggt cagctatgtc actcaaaccg gtctctttat tggtcttgat
    17521 cgtacctcga ccatccgaat ggaacaaatt accaaccgtt cgattaattt agaaaaagta
    17581 gtaaaagtaa atgatctttc acgtaaatat gttgcttcag agctaacatt agaagaactt
    17641 tactgcgaac tgcaagcaat cgaccgagac cgttctttct ttcctgtctg gttgcaaatc
    17701 gttagcgcgg cagtgatcag tggaacaatt atggtgttat ttggcggaaa gatgaccgat
    17761 ttacctgtga ctttagtcat tggaggattg ggatacgcag cttatctata tagtttgaaa
    17821 ttttttagaa tcaaattttt atcggaattt ttatcttctt tattgattgg catagccgct
    17881 atctacagcg tacgttttgg cttaggaagc aatcaggatc taatcattat cggatgtgtg
    17941 atgcctttag ttcctggagt tcaaattacg aacgctatcc gtgatttgct agctggacat
    18001 tatgtctcag gagtttctcg cggaacagaa gcgatgatga ctgctacgat gatcggtttt
    18061 gcgattgctt ttattttcca gcttttttat taggaaagga acacaagtat ggggacgata
    18121 tttattcagt tttcttttag ttttttagcg actgcggcat ttgccgttat tacaaatgta
    18181 cctaggcgtt cattgatttg ttgtggtctt tctggtgctt ttggctggat gatctactgg
    18241 atctgtgttc aaataggcgg atctgctgct tttggttcat tgcttggttc tttaggagta
    18301 gcattcatca gcgatctttt ctctaaacgt ttgaaaatgc ccgtaacgat tttcaatatt
    18361 cccgggatgg ttcctctagt ccctggtggt ttagcttatc aagcggttcg aaatctcgtt
    18421 actgaatcct atcgagaagc ggctcattat gcggtccaag caattatgat tgctggagca
    18481 atcgctttag gtcttgtatt atcagaagtc tttaaccata acatccgtaa tttcaaagta
    18541 aagcgtgacg caatcatgat gaaacgaaaa aaacggcttt ttaaataaac gaagtgtaac
    18601 aaagaaaagg ttgtgaaaga gacgttcagc cttgagcgat gacaaaatat ctcacaaaca
    18661 ttgcgacaag taaccgcagg agcaataaga agtaattatg agtattaaaa aaagttttgt
    18721 aaaaatagct tctcacattt ttacataaaa ttgacttaat actgagaaac tgacttttga
    18781 acaccctcta tctgtaaaaa aggggctgcg acatgatttt tgtcacggcc cctcttcttt
    18841 attcaaattt tttccaaaac gttcgttgat aataaacgat ccatagagcg gaaagtatta
    18901 gaactaaacc gatcacagga atattcacta accaaaatgg ataaaacaaa gccaacattc
    18961 cgtataagac gataagaata atactgatga tcaatgaacc catcatagtt gcgactaaac
    19021 ccaaacttcc tgaacctctg ttaaataatt ggttaatatt ggtccagttc agcagcagca
    19081 accgataatc tctagcgaaa taacgtagtg acaataagta gcagccgaat aaagaaccaa
    19141 atagcaagct agggataaaa aacaaaggca gctgaaaaga cagtccgctt aataatgcga
    19201 tcccaccagt taaaaaactc tgcaatatcc atccgaatct gaacttttct tttaaatatt
    19261 ggttcataga gattggcaaa gaacggataa acagaaaatt ttcttgatcc aaagaaataa
    19321 gattgctgat aaaagaagtc tgattaactg ttaagaaagc caatgcgatc cctaccagga
    19381 aaacaacacc gattaactta ttatctaaat cagttaattt tatttcgcct cctagggcaa
    19441 aagcaagaat aaaaatgatt ggagttaaca aggaagaaga aagaacttgc ataatcaaat
    19501 taggttcttt tactaattga gcattgtaac taaataaaag ctgatgcaca ttttggttct
    19561 ttttatgggt tctttttatt ttgaactcac tgtttgaatc agtcagttgc tctgtaagct
    19621 ttggtactat cagctgtttt acagcaagga aaaatcccag agccgtgata gctagtattc
    19681 cccaacccaa taaaccttgt tgagaaagtg gctgactggc agcatcatag aatggcaata
    19741 atatcgaaat cggatgccga tctgttaact cattttcaat agtccccgtt tgatgattca
    19801 tccacatgat tccagcaaat gcgatcagca tcgagctgcc aagcaagata ctagaaactg
    19861 tttttctatg ttttttaaac actgctgttc gagccaaacc aaaaacaatc aaactagcca
    19921 gacaaaaaag aataatcaaa aatagagaaa acaaaaggat tgagataatg atagtaagca
    19981 aaatccctag atcagctcgc catccggtta aaataaacat gactagaagc ggaaaaacaa
    20041 aaggaatgat ggtcaaagca actaccaaaa tctttgctga aaaaacctgt tcttgtccaa
    20101 aaggcagagg caaaaatact tgcaggtcat ttccttcaaa aaagatatta taaatgactg
    20161 atatactttg agttaaacct aacataccaa aaagtgccac gtaataagta aagaaacctg
    20221 gcaatttaac aaagttcata gcaaacatag caaatccgta aatcagtaaa aaaatcagcc
    20281 ctgaaaaaag attttgagac aaaagataga tagttaatcg ctttcccttt tttcctttct
    20341 ctcttgcttt attcgtgagc tgtggattaa catataaaag attaactcga attaattcta
    20401 ataattgtcg cttatacata cggtccatct cctgtcgctt gccttccagc cattttcaaa
    20461 taaatctttt ctagcgtttc atcaggtgag ccattcaata attcactaac tgccccctga
    20521 taaatcaatt cacctttctt caaaatagcc agtttatcgc ataactgttg tgcggtatcc
    20581 aatacatgtg tagaaaaaat gactgttttt ccttttgcgg catgagcctt catcatttct
    20641 ttcaaatcaa atgctgcttg aggatcaagt ccttgcaaag gttcatccaa tacccaaata
    20701 tctggatctg gcagcaacgt gccgatcaaa atcgtttttt gacgcattcc atgtgaaaaa
    20761 cttgcgattg tttcattttg atgactatac atatcaaaaa gcgctgtcaa ttctgctaaa
    20821 cgcttttctt ttttttgtgt gtctaattca taggcagctg aaatcaagtc ccaatattct
    20881 ccagccgtca attgtaaaaa aatatctggg gaatcaggca cataaccgat tttttgtttg
    20941 atactcaatc gattttccgt caatttcatt ccatctacta aaatcgttcc cgatgatggt
    21001 tcaataatac taactaaact tttaatcgta gttgattttc cggcaccatt atgtcctaaa
    21061 aatccaaaaa tttccccttg tcttatcgag agagacaagt cttttaatgc ttgttttttc
    21121 ccgtaacttt tacttacatt gatgaattca atcatttctg tactcctttt gtttgttatt
    21181 actttttatt gtacccttcg ttattggtgg agtaaatgtc aaaaagagtg cataacaaaa
    21241 aaggatagaa acgactaggc tgctacttgg gttgttctct tctacaggaa aacactcttc
    21301 taacaggtaa gatatgagtc tttgttttct ttaaaatgat tcattttcta tcttttcttg
    21361 cataaaattc tttagtttat caatacttct ctttcccatc tctagttgtt ctccatttgc
    21421 aaatgttact atttcgttta ctctgctaat agatgtaatg ttttcagtat taatgatata
    21481 agcttttaaa tctttacata aatactcata ttcgagtgat tttttatatt ttttaattgt
    21541 gccgtttacg agaatctctt catctttcaa tactaggcct attttatttt tataacctgg
    21601 catgctcatt agataaagga tttcatcgta atggatatag tgatcgctat taccataacg
    21661 gacagttgtc cacctttttt tcgtagcatg ttgaacagga tagttttctt tttctttcaa
    21721 taagtaactt tggatgcttt ttttattttt ttcataagtg aattctttta tcaaataacc
    21781 actaggcgta atctttcgat taataacagt tattgcttta ttcggatgag acgttagata
    21841 aacaatttta cacttttcat tcttttctct aagcatttcg cctagttcga taccgctata
    21901 ataggcgttc aaatcgatgt ctaggaaaaa aatatctgag gaatagattt cattattttt
    21961 aatgaattca acaaattgta taacgttcaa tccctgaacg atctcaaatt tccaaggact
    22021 taataaaatt ctggattctt ccaaaatttc tactagcatt ttttcaaaaa ccaaactatc
    22081 atccaaaata aatatacgcg ttaccataaa aagtacctcc actcgatatt ttactatcaa
    22141 aatcatttca tacaactttt caacatacat gttaggaata aattgtaatt ctcttcacaa
    22201 tcttttccaa cacctttgaa accgatatca aatactttca ggatgctgct tctaaaataa
    22261 atatcaaaca aatgaataca tcatgcaaaa aaagccagac aaccgacgtc cttgcgtgtc
    22321 agctgtctga gctatgttta tttattttgt tcttttaaaa agaacgatac acatactgat
    22381 ttttcggagc agagactttc tcagcgtttg taacaactac agatgggatt tcacgcttga
    22441 atggttgata atagtctgat tggatggttc cttctatttt ataccattca tcatttttaa
    22501 ccgttactcc ttccggcata tgcgtcaaca aaccaaagac tcctgaatct gccacacaat
    22561 ggataatgcc gaatcggaac aagaagatat ctgtattgct atcgttcggt gtttggtaaa
    22621 caaatccttc atagctgatt tttttgccaa tgaattcgct agggtaatta taaattagct
    22681 ccataacttc taaatagttt tcatctgtga tcttgatagt ttgcttatcc ccatactttt
    22741 ctttcaactc attcatttgg tctaagtagt ctgatttgtt gaaataaata ctggtatccg
    22801 gctttaagta ttgtgtctgc atctccggat cccctactga ttctttactt actgggaaat
    22861 taaatccttt ggcttctacg atcgtagtgt cgagactaac tgttggaaac aacgtcccca
    22921 cgattactgg caaagctagc agtacataag cgattccacg ttgataaggt tttgacaacc
    22981 catggtcatg atcgtgctcg tgtgcctttt cttctgcttt tccgtttttg acccacaaat
    23041 acagctgaac taaagccaaa agagcagata aaatcattga aagaatagct aagtagcgat
    23101 aatggacatt gatatattga tcgagtttgc cagaaacttg caagtacatc atcaattcga
    23161 aatacccaga taaaatcaaa aaccgcagca tattttccct cctaaataaa taatgtgaat
    23221 ccaataacgc taagggcaat cagtccgatc agcgataaaa taaagcgtcc tgtaaaatat
    23281 cgtttcatca tcagtagatt tttgatatcg accattgggc caaagaccaa aaaggcagct
    23341 acaggtgctg tgccgaacag acttaacaaa gaagatccta taaacgcatc tgcttctgag
    23401 caaagagaca tcgtaaaggc caataacagc atgatgataa tggctaaaat ctttgttgag
    23461 ccgagcgtta gcataattct agttggtaaa taagtctgca tcgcagctgc gattaatccg
    23521 ccaatgatca aataacgacc tgtatcaaaa aattcgtcga ttgaatgtgt caacacatgc
    23581 ccagtttgat ggatcagctg attttttggt tcattcttct cactttgttc ttcttcatgg
    23641 acatgatgat ggtgattttc tgctacttta gacgtgattt tttctttcaa tacagcgtct
    23701 ttttgaaaat aggcaagcca gacaccaatc acaagggcaa caaaaaagct gcctatcacc
    23761 cgccagcttg ccatctgcca agaattgcca aatgcgataa aagtggaaaa aatcacgatt
    23821 ggattgatga tcggagcagt cagcataaaa gcaaacgctg tgtgaactgg tacgcctttt
    23881 ttaacaaatt gatgaacgat cggtacgatg ccgcattcac atgaaggaaa gaaaaatcct
    23941 aagatcgaac cagtaaaaat agagaagata cgattttcag gaagccatct cttcacacgt
    24001 tctggggtca aaaatacttg taaggcgcct gagataagac agcctaataa tacgaaaggt
    24061 aatgcttcaa taacgatcga taagaaaatc gtactcatct gcaaaaccga atttggaata
    24121 aaagaaaaca tgagtttcct cctttttatt tctagttcat tcgctttgca aatatacgct
    24181 tttattcaaa aaaaacaagt tgctctgtaa atttttacac aactcttatt ttttaccaaa
    24241 gcacttcaat tgactttttc tgttattccc attaaattaa ggtctcatac atatcacttc
    24301 tatcataaaa gggagaataa aaatgaaaca aaccactaac ttgactgaag ttcaagacat
    24361 actgcaacag tcatccgttg ccgtcattta tctttcgatg cctaattgca gtgtttgtca
    24421 cgctgttcgt ccacgactag aggaacttct cacacattat gatattccgg cacttcattt
    24481 ggatgcattt gaaacaccag aagtagctag taaatttgaa gtgctgactg cgccagttgt
    24541 cctgattttt catcaaggaa aagaagtctt tcggcaagca cggttcatcg actttaaaaa
    24601 aatccgttat ctactagatg aactgacagc agaagatgat tccctttctt atgaagaaat
    24661 cttccgaaca aaataatcgt tgtccaaaca gaaaaaagcg attgaacaag tgaaagtttt
    24721 gccttcattt gttcaatcgc tttttatttt tattctgctg tattttcgga atgcgcattt
    24781 gcgtcagaat gcaagaaata gatcaaggtt tgcaattcat tcgtcaaatc aacattttgg
    24841 atcaatacat ctgacggagc attcaatcga gcagcggtaa agttcaagat tcctttgatt
    24901 cctgcttccg ttaactgatt gactacttct tgtgctcttt cagcgggtat cgttaaaatt
    24961 gctacttcga tttgttggat cttgatttgt tctgacatat cttccattgg ataaacgggg
    25021 ataccgtcta cgatgcgccc aacgatttcc tcattcacat caaaagcaca actgatacgt
    25081 atgctattac tttgatggaa tttgtatttt agtaaagcac ttcccaagtt ccctacaccg
    25141 atcagcgcaa catttgtcaa ttgatcgtcg tttaatgtct ttgcaaaaaa gtgcataaga
    25201 tcttctacat cataaccata cccacgtttt cctaattcgc caaaataaga aaaatctcga
    25261 cggatcgttg cactatctac ttgaacggct tcacttaatt cagttgaaga cacttttttc
    25321 tttccagcat tatttaaaat ccttaaatag cgataataca aaggcagtct tttagctgtc
    25381 gcctttggaa taatatgatc tttcacgaaa tgacctccac gtattgtcta attacatctt
    25441 tgatttctcc atcatagcag tatttatagg aaaaaatcaa ttccattgct cagatattgt
    25501 gaaattttat tctttattca tttatttatc atttctgcaa atctcgcagt ataatggaat
    25561 ttatggtaga ctactaattg aaaaatagtt ttttatttga ggagaattca caaagtagaa
    25621 aagaggattc catgatatta ttacaagcca atcagattgc tcgccatttt ggtgcagaag
    25681 tcttatttga aaacatacat ttagaaatca gtacaggcgc tcgtgtcgct ttagttggca
    25741 gaaatggcgc tggaaaatcg actttattaa agatcattgc tggaattgaa gcacctgatg
    25801 aaggaaagat cgctaaaaat aaaacagcga ctctcggata cctcgctcag gacacaggac
    25861 ttgattccaa tgaaacagtt tggaacgaga tgctgaaagc ttttgaacaa gttagacaaa
    25921 tggaagagcg gatgcgcgag ctagagattt tcattagcga aggtacgcca gacacacctg
    25981 cttatagttc ttatttaaaa gaatacgacc ggctgcaaca cgatttttca gatcgaaacg
    26041 gctatggtta tgaaaatgaa attcgttccg tattgcatgg gtttaaattc gattcttcat
    26101 tttatgatca gaaaatcgat actttatcag gcggacagcg cacacgttta gctttagctc
    26161 gcatgctttt gcaacaccct gacattttga ttctagatga accaacgaac catttagata
    26221 tcgagacact ttcctggctt gagaattatc tgcaaagcta tactggtgca ttattgattg
    26281 tttcccatga ccgttatttt ttagataaag tagtcaatga agtctatgaa ttaagcagaa
    26341 gaaaaatgcg ccattacaaa ggtaactatt cgaaatatct agatttgaaa gcagaacagt
    26401 tagcaagtga atggaaggct tatgaaaagc agcaaacaga aatccataaa ttagaagact
    26461 tcgttgctcg gaaccttgtt cgcgcctcta ccacaaaacg agcgcaaagc cgcagaaaga
    26521 cattagaaaa aatggaccgg ctggatcgtc ctcaagggga tgaaaaacaa gcaaactttc
    26581 tattcagtat agaaaagcct tctggaaatg tagtcttgca aatcgaagat gccgctatcg
    26641 gatatgataa tgtcacctta tctgaaccaa tcaatctaga tatccgtcgt caagaagcga
    26701 ttgctctagt aggtccgaat ggtatcggga aatcgacgtt gctgaaatca atcattcacc
    26761 agatcccttt tatccgtgga aaagaaacgc tagggacaaa tgtcaccatc ggctattacg
    26821 atcaaggtca agctgatctg catacaaaca agacgatcct agcagaattg tgggatgagc
    26881 atcctaccac tccagaaaaa gagatccgaa gtgctttagg tgctttctta ttttctggcg
    26941 aagatgtaga aaaaccaatc cctctgctaa gtggcggtga aaaagcacgg gttgctttag
    27001 ccaagttagc gatgaacaaa gaaaattttt tgattttgga tgaaccaaca aaccatttag
    27061 atattgacaa caaagaagta ttagaaaatg cattgatcga ttatgacggc acactgcttt
    27121 ttgtttccca tgaccgatat ttcatcaatc ggatcgcgac aaaagtcgtc gaactctctg
    27181 aaaatggcag caaagtctat ctaggagact atgattatta tttagagaaa aagcaggaag
    27241 aagaagaaat cgccgaattg ttggcacaag atgagccaga atctgctcct gctcccacga
    27301 acaaatctga ttattaccaa agcaaagaac agcaaaagct tatccgtagc cttcaacgaa
    27361 aaattactca ggttgaagaa gaaatggcgc ggatcgatga atggatcgat cagttggaac
    27421 aagaaatggt cgcgccagaa aacctggaag atcacgtaaa actcaatgag ctgaaccaag
    27481 atttagaagc tgctagacaa gatcaagaaa caaaattgac ggaatgggaa gaactaagct
    27541 tggaattaga agaatatgaa aattaacgaa aaaaccaaaa cagaaaccat tcatgctgtt
    27601 ttggtttttc tttttttatt ttatcaaaca aaaattccat atttaccttt ttcaccaata
    27661 agaagaccaa ttactagtca ttctcactaa agcttctaaa taatagtaat caccccaaat
    27721 acaaggtgta tttaccccat tatttttggg cttattataa acagactgtg ttaaaaagcc
    27781 atcttcttct tccgttgtag catatctttc tttcaattgt cgcataattt tccaaacagc
    27841 agactggtat aagttctttt ctgttttgtc taatagacct gattctatta attctaataa
    27901 tccacaaacc atgatcacca tactagatgt atctttttct tctctgctag aatcatcaaa
    27961 gatcaaatcc caataacaaa tggtatcttc tggcaaccga ttcataaaat aattggctaa
    28021 tattttgctt aaatcaaaat atttttgttc tttcaaataa cgataactta atgcaaaacc
    28081 gtaaatcccc catgcttggc ctctagccca acaggaatta tcactataac cttgatgcgt
    28141 acttccatat cttggttttc catctttgac atccatataa aatgtatgat aagttgaacc
    28201 atcttctctt actaaataat ctgctgcatt ttgaatatga gcctgagcag cttttttata
    28261 tttttgattt ccagtttctt cactcgccca atacaataat ggaagattca tgcaacaatc
    28321 catgatcatt ctaccttgtt gtgaaggatc actaggatct ccccaagctt gtataactcc
    28381 tgccttctcc caaaaacgct gaagtaatgt ttctgcagca tcaattgaag cttccttcat
    28441 ttttcgattt cccgttattt tataatctgc tacggttgat aaagaataca aaaaaccaag
    28501 atcgtgatga ttagtgataa tttgacagtc aatcctgtgg ataaaatcta tatctgcttt
    28561 ttcagctgtt tgttgaaata aaggatcacc cgtcttctca aataacaacc aattaattcc
    28621 tgtccaaaat ccttctgtcc aaccaatatt gtctcttaat ggataacgtc cttttatagg
    28681 acactcgctt gggaattgat actgactgtt actgatacgt ttgattaacc tctccgtgtg
    28741 tctgcgacaa cgctcgatct cattattcca ttctttttcc attaattctt tataacattc
    28801 atttatccat ttttctggat gtattatctc ttcaaacatc actttatcaa gcatttcccc
    28861 accagccttt agcataattt tagtcttttt ttattgtttt tattttggat agttagcccg
    28921 gttgtcccat caaaatcaat tttgggacga ttgttccata cttctaaact ataatcccga
    28981 tcttgatgag caaccactcc tgttccgagc caatgggttc cttttccaaa tgtaccctct
    29041 aatccaggaa taaaagtgtt ttcccatgtc atcaagtttg tattgggcaa acccataata
    29101 gctgtggatt ttcgtttaat agtatcgtca cttaaacaga taatacctga aaagccagct
    29161 tcactcaccc tatagttttc cttgtcttct tctatgatta ttccttcttt ctcaggagaa
    29221 cattcaatag caaaccctgt ctcatataga acatattctg tatctaattc tactttgtgt
    29281 acgcgaatct gccagccttc aaaaggaata agccaagttc tgatttttgc ctgtaaagta
    29341 ggttcccatg tagaggcaag tacctctttc ttacatacaa tgtctcgtac attatttcga
    29401 acgatgaact gtccataggt tttgatgctc tcattcttaa aactggtcgt gatatatgtg
    29461 tccgctcgct gaatccctag cattgaatcc attgccattt ctgctttcaa ttgattcgct
    29521 cgcggtatcg aaaaaccaaa ttgactagaa taagcaaatt ttaaatattt ttcattggtc
    29581 aatgtatgga aatttggccc taattgtccc gcattcaaaa aaaatgtatg tccattatca
    29641 tgttgtatga gcaaattggc ttctgaaaga agtttagttc cttcacgaat aggcataggc
    29701 atttctttag ccgtccaata ctcatggtct tcaggtagcg ccaacaataa aaaaatctta
    29761 ttcagccata atggagataa cgtactatta tagggttcag tcaatgtcaa ttgagggtag
    29821 gtataaccaa tattcaggat acctttttca tcaaatattt ctttttgcat ccaccatctt
    29881 atattccgat tgactaaccc cttgatttca cctaatttaa aaggcaaaag atcggcccac
    29941 aacatagctg accaaaagct tgaaactgca aaacgataaa tcatgcttcg accaaaaggc
    30001 acatttgcac catcttccgc aaaaaaatga atatagtctc tagaaaaatc aatagctcgg
    30061 ttcttatata tctggctaat gggcttttct ggttctagta cgctataaat caaaccataa
    30121 taatgaaatg caaaaggatt ataataatct tggcgacctc ttgaactgtc tcgataccag
    30181 ccattttgaa gataacaatt ttctatatta tcaaatgctt ctttcagtgc tgattcttta
    30241 actggataac caaatttttg gataattgtt ccgacaatta tcttaaaaaa ttgccaatta
    30301 ccatctgcac attcatattc aaaaatttgc gagaaccaat gaataatctg gcttttttct
    30361 cctgtatcta attttttcca taataattgt tcatgatgat ataacgctaa taacattgcg
    30421 ggcatttcta ccatacgctg gtctctttca tgtatttctc cccaataatc gggatgggaa
    30481 ggatctgttc cagcttttat tcctgataga attaatttca accatcgttc atctaattgg
    30541 tcaattgcgg gccccgctcc ccataaaacc cgagagaatc cttccattcc tgcaatttta
    30601 tttccatatc ctaccccttg atgtatataa tcaatttgtg cgccacttgc tcgataaaac
    30661 ggctggagtg gttgatttat ctttttaaat aagtcaaagt aatcctgtct ggtccttaat
    30721 agtggtactg gatgtttcat tgtattttct cctcttttta ctaccaaata gctaattccg
    30781 actgttctaa tcgaagtaag ccttcaataa aaaaataatc agaatagatc agtggcacat
    30841 tataagtcag ttctctatgg tatgcttctg ctccgcctcc aatgatccca tcttcatcca
    30901 tattccaatt tgcatagtgc ttttctgtct tttggagtat attgatagca gcttcatgat
    30961 acatttttga tcgtacagag gaaacatatc ctgctaattc cagaagaccg catgcagcgc
    31021 atactccagc actggtatca atattcgaat cttttacagc aaaatcaatg agaggaatat
    31081 aaccagtttt ttcgattttc tgaataaaat ttactgctat cttttctgct atagctagat
    31141 agtacggatt ttttgtgtaa cgataactta acgcgaatcc atataaagcc catgcatttc
    31201 ctctgctcca acaagaattc tcattgtatc cttgcccgcc aagtaaccga atatatttcc
    31261 ctgattctgc atcaaattct gcgatatgcc cggttgatcc atctttcctc actagatact
    31321 tagctgttgt atctgcatgc tgccgagcaa ttttagagaa cctcggatca ccagtttccc
    31381 tcgaagccca atacagtaat ggtaaattca tcatactatc aataatcatc caaccaggtt
    31441 tatggtcatt ccatgctact aaatagttcc ctgaaatatt atagcgtcca gcaagtaccg
    31501 tagctgcatg taaccctagt tgtcgactat gtttgttttg agactgttga taatgtgcaa
    31561 tagccgatgg taagaataaa aaacctacat catgatgaac gtctgaaaaa tggtacaggg
    31621 cagattctaa taattgttct tgttgtattg ctgcctcttt gaacttttct cgttttgtct
    31681 tgtgaaagag ctgccataaa ataccactcc aaaaaccatt ggtccaccag tcgattcctc
    31741 tgtcctttat tacgtctgta tattttccgt tgtaagaaat atatggaatt ttattcccca
    31801 ttctgtctaa ttccgcatct atcttttcag aagctacatt caaaattttt cttgaccatt
    31861 ccttcgtctg ttcattcatg gatatcccgc cattctttta atttttatga atgtggagtt
    31921 gctcctagaa cgaactagat ggttaacatt cgttattttt tttacttatt tgcagctcca
    31981 atgtcattct ccttaaattt agactgcgcc cacacataaa tcaagaccat tgggatcact
    32041 gaagttgcta aaattagcat aattgcgcca taattaattg gctcacctgt actagaaacc
    32101 gtcatatttt tgataattaa gggaaccgta tatttatctt tatctgaaag catgactaat
    32161 ggaaatagat attgattcca acttcccata aagataagta aaccactagt aataatcgta
    32221 ggtgataaaa tcggtacagc gattttcgta aaaatcaccc actcattggc accatcgatt
    32281 ctggcagcct ccatcagtgc tgtaggaaat tgactgctat attgtcgcat cataaacact
    32341 gaagttgtac tggcaatcga agggatgatc acacctgcat aagtattcga taatcctaaa
    32401 cgactcataa tgtaaaataa aggaatcaat gtggtaaaaa aaggcaccat cctagatagc
    32461 ataactgtat tgaacaacag tttattcccc ataaaacgat actttgctaa tgcataaccc
    32521 gccattgtag aactggctgt agctaaaact gtactgatta cagcaataac aatcgaattc
    32581 caaataatca agggataatt atatctcgcc atgatggctt gccagttttt taatagcata
    32641 tccccaaact tgaaattgat tccgccactt aaaatttctt gattactttg cgttgaagct
    32701 acaatcatat ataaatatgg catcaaaaat attaaggcac caaacacaat aatgacgtac
    32761 gtaaaaattc tgctttgtat cttttgttta gtcattttta tcacctccga atttaaattg
    32821 aatagccgat aatataacag atacaaacac catcgtccag gcaatagcag aggcttttcc
    32881 aaaatcaacc atttcaaaac ttgttttata taaattgact cctacgacca aagctgaatt
    32941 ttctggtcca ttggaagtcc caaagaatat atttgggata ttgaaattac ccaagccatt
    33001 gatagtggct aaaactgtgg ccattaaaat gattggcttt agcatgggga tcgttaataa
    33061 aaagaattgc cgaaatttcg atgctccatc tatttcagca ctttcgtata tctctttaga
    33121 aatcccttga agaccagcta aaaataaaat agtgttatat cctacactaa gccaaatcat
    33181 cgtgatgatc attgatattc gtatccaaaa aggatttgtt aaccactgta caccgttaat
    33241 tcctagcgca ttcaaaaatc cattgaataa cccagtcgga ttgaaaaaag tcatgaatac
    33301 ggaagctaca gccaccgttg atgtaatggt tggaatataa tagacagttc taaaaaatcc
    33361 ttttcctttt aactgtgctg aattcaataa aacagcaaag taaatagcta atagcatcgt
    33421 tattggaatt gatcctgcca tgataatcaa aacattcgtg taagatttaa taaacaatgg
    33481 atctcggaag atagctagat aattgtcaaa tccaacaaat tcaaatgagt agccaatttt
    33541 cataaaacta aaagcaaacg agataatgat gggaatcaaa atcgtcacaa taaagaaaat
    33601 aacaaaaggt gtgaccaatc cataagcact ttttttatga gacgtatctg ttgctttttt
    33661 cttgctgttc tttattgtct tgcttggtaa cgaagattgc atcatcgtta agtcctccta
    33721 atatttttta atcaccagtt aattttacgc cgtacttatg agcaaaattt tctgcttctt
    33781 ttagatatga attttcaaaa tcacctgttt gccaatagtt atatgcagcg gtagtcaaat
    33841 aagacgtagc atctgaataa gtggctggta aaacagtatt tgatgtattt tcattgattt
    33901 tattcaatag ttcatagtat ttttgtcctc cttagtagtc aaactttttc tcagctgctt
    33961 ctgtttgata ggccaatgag ttagatgtag ccacgcccag ctccagtgcg ttggctaagc
    34021 attcttcatc tgtcagcata aatgtaagaa attgttgtgc cacttgtgga ttttttgcat
    34081 ctttagggac ataaaaactt gatcctcctg atactgcacc ttttcctgga ttttcttttg
    34141 aaaaaggaat cagtggagcc atgcgccatt tgtcagatgc atcaggaaaa ttcaaagaca
    34201 tattcgtagc ataccagccg ccagcaacaa acattgcaga ttcttgaaat gctttctcag
    34261 catcttgtgc accgtagaaa tgtacaatat ctgagtcgat catttctttg attaactttg
    34321 cagcatgttt cgcttcttta gtattcagac ggatatttcc ttcttcatca agcaaagatt
    34381 gattctgctg ggctagcatg ttgataaaca attcttggtc cccagattct ggcaaggcaa
    34441 ttccaaaact accagttttt tcttttaatg cttttgccac ctggatatat tcttcccaag
    34501 aactgatttc ttcaaaatct acacctattt cagcaaattt ttttggttga taataacaaa
    34561 gtgctggggt aaaatcacta gcccaaggaa taatcgtttc attactcgtt tgttgacgca
    34621 aaatattcaa tttttgatca taaaactgat cgccatattt gtcataaaat ccatattcat
    34681 cagcactata aaaagcatct tgaaattttt ccagcacacc tgctgctgaa gtgtctgcca
    34741 tggagataat atccggcata tcttcgtgtg ttaccaattt tggggtgatc atttgtactg
    34801 ttgctgttcc cgaagctaca ttcacaattt ttaagtcaat atttgctcca gttttgcggt
    34861 tatagatttt tgcagcattt tcaacatagt ttgtcagttt gccgtttgcg acatatactt
    34921 ctaatgtagt ggcttttttt atcattggat ctgcgatgtt tgctgttact tcttcgttag
    34981 tttttccaca tgcacttaag ctgaataata gggtaatgtt tagcaaagct atcaccaatt
    35041 tgtatctttt tttcatgtct atcccttctt tcttttcaag ttcttatata aaacgctttc
    35101 acttatgtat attaacggaa ttagtaacac aaatatttat ataaaaaaat attttacttg
    35161 tcgttttggc ttttcatttt tgttataata gtcattaatt ataaatagaa agctttttat
    35221 ataaaaagag aaaggaaagt ggttcttttg ttaacaaaca accaatcctc caatcttgtc
    35281 aaaaaaacac taacctattc catagatacc catcttcatt tatctgctgc tccctatttt
    35341 cgactactaa taaatgaaag cgctaattta tatgctgaat ttgcacataa atctatagaa
    35401 ctagataatc cttccctttt attcattgat aaacagcaag aagtccaaat cttttctact
    35461 caaaaggaaa cacaaacttt tatcattatc cagttttatt ttgatgagca attattagc
//
LOCUS       DADVXV010000020        34955 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.020, whole genome shotgun sequence.
ACCESSION   DADVXV010000020 DADVXV010000000
VERSION     DADVXV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.020"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="KB969_000949"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="KB969_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBB6868955.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2020..2922)
                     /locus_tag="KB969_000950"
     CDS             complement(2020..2922)
                     /locus_tag="KB969_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6868956.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2919..3611)
                     /locus_tag="KB969_000951"
     CDS             complement(2919..3611)
                     /locus_tag="KB969_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBB6868957.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3654..4295)
                     /locus_tag="KB969_000952"
     CDS             complement(3654..4295)
                     /locus_tag="KB969_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6868958.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4333..4647)
                     /locus_tag="KB969_000953"
     CDS             complement(4333..4647)
                     /locus_tag="KB969_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868959.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4635..5987)
                     /locus_tag="KB969_000954"
                     /pseudo
     CDS             complement(4635..5987)
                     /locus_tag="KB969_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5984..6916)
                     /locus_tag="KB969_000955"
     CDS             complement(5984..6916)
                     /locus_tag="KB969_000955"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBB6868960.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6913..7689)
                     /locus_tag="KB969_000956"
     CDS             complement(6913..7689)
                     /locus_tag="KB969_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBB6868961.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7743..10928)
                     /gene="carB"
                     /locus_tag="KB969_000957"
     CDS             complement(7743..10928)
                     /gene="carB"
                     /locus_tag="KB969_000957"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBB6868962.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10933..12009)
                     /gene="carA"
                     /locus_tag="KB969_000958"
     CDS             complement(10933..12009)
                     /gene="carA"
                     /locus_tag="KB969_000958"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBB6868963.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12014..13294)
                     /locus_tag="KB969_000959"
     CDS             complement(12014..13294)
                     /locus_tag="KB969_000959"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBB6868964.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13313..14239)
                     /locus_tag="KB969_000960"
     CDS             complement(13313..14239)
                     /locus_tag="KB969_000960"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBB6868965.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14252..15535)
                     /locus_tag="KB969_000961"
     CDS             complement(14252..15535)
                     /locus_tag="KB969_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBB6868966.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="KB969_000962"
     CDS             complement(15549..16088)
                     /gene="pyrR"
                     /locus_tag="KB969_000962"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBB6868967.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16323..17234)
                     /locus_tag="KB969_000963"
     CDS             complement(16323..17234)
                     /locus_tag="KB969_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6868968.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17231..17695)
                     /locus_tag="KB969_000964"
     CDS             complement(17231..17695)
                     /locus_tag="KB969_000964"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBB6868969.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17700..18398)
                     /locus_tag="KB969_000965"
     CDS             complement(17700..18398)
                     /locus_tag="KB969_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6868970.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18385..18771)
                     /locus_tag="KB969_000966"
     CDS             complement(18385..18771)
                     /locus_tag="KB969_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868971.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18918..20588)
                     /locus_tag="KB969_000967"
     CDS             complement(18918..20588)
                     /locus_tag="KB969_000967"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBB6868972.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20771..21004
                     /locus_tag="KB969_000968"
     CDS             20771..21004
                     /locus_tag="KB969_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBB6868973.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21103..21534)
                     /locus_tag="KB969_000969"
     CDS             complement(21103..21534)
                     /locus_tag="KB969_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBB6868974.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21613..22026
                     /locus_tag="KB969_000970"
     CDS             21613..22026
                     /locus_tag="KB969_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBB6868975.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22064..23212)
                     /locus_tag="KB969_000971"
     CDS             complement(22064..23212)
                     /locus_tag="KB969_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6868976.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23334..23930)
                     /locus_tag="KB969_000972"
     CDS             complement(23334..23930)
                     /locus_tag="KB969_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6868977.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="KB969_000973"
     CDS             complement(24130..26772)
                     /gene="alaS"
                     /locus_tag="KB969_000973"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBB6868978.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27160..27591
                     /locus_tag="KB969_000974"
     CDS             27160..27591
                     /locus_tag="KB969_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6868979.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27636..28985)
                     /locus_tag="KB969_000975"
     CDS             complement(27636..28985)
                     /locus_tag="KB969_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6868980.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29055..30218)
                     /locus_tag="KB969_000976"
     CDS             complement(29055..30218)
                     /locus_tag="KB969_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6868981.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30347..30670
                     /locus_tag="KB969_000977"
     CDS             30347..30670
                     /locus_tag="KB969_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6868982.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30853..32202)
                     /locus_tag="KB969_000978"
     CDS             complement(30853..32202)
                     /locus_tag="KB969_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6868983.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32271..33224)
                     /locus_tag="KB969_000979"
     CDS             complement(32271..33224)
                     /locus_tag="KB969_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBB6868984.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33326..34516)
                     /locus_tag="KB969_000980"
     CDS             complement(33326..34516)
                     /locus_tag="KB969_000980"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBB6868985.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9949 a         7639 c         6119 g        11248 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaaattctg tcacaacccc tcttttttga
     1981 tcaacggtgt tcaataaaca gcgttctcat ctgcttttct tagctctgct ggtccagtaa
     2041 ccgagtaagc tctttgataa atctttgagc gatttcactg agcggacgtt tcgccgaata
     2101 aatgatataa aattcattta gttcgccttc tgccaaaggg attaaccgca agtgctcgcg
     2161 aatccctcca atcacaatac cagatcctga agcgtaagca tcagtttcaa gaacgatatt
     2221 catcaaagta cctcgatcac tcgtataaat cactgtttct tgatcaggga tctcgataag
     2281 gtcttcataa aaatacggga aattatttcc atcctgtgta aaacgaactt gaggataaga
     2341 taacaattct tctttggtga tctctgcgtg ttcagctaat ggatgtcctt gccttaaaaa
     2401 aatatgcgtt ttgaattttc caatgctgcg gccacttagc tctccttgtt gtaaatatct
     2461 tctgatacca gcttgattat gctcattcat ataaataatg ccgatctcac tgtgctgctc
     2521 tttgacttct tcgatcactc tcgctgttgt cgtctccatg atccgaaatt gtttgatctc
     2581 gtctttgaat tcctcgagta gctgtgcggt caaaggacct aagaaatcat aatgctgggc
     2641 agcgatcgaa aaattgtctc tcttttcact cgttagatag tgagtttcta atgtatcaag
     2701 ctggaccaat attttctcgg cacgatttaa gaagtcttgc ccttcttctg ttaaatatgc
     2761 ccctcgattc gttcgagtaa acagcgtgat ccctaactcg gtttctaatt ctttgatacc
     2821 agctgaaaga cttggctggg agacaaacat tttctttgcc gcttctctga aactaccatt
     2881 gtttgctaca gcgaccacgt atttcatctg ctgaatattc attgctcaaa ctcctcgaaa
     2941 taataaattt ctcttccatt caagggctgg attggtcggt tgttcggtcg agcatactga
     3001 ccatcgaagg ggagaagaaa ctcttggttc agttttccta catgatccat tacaaaccat
     3061 tggattggcc cgctggtagg cggagttgtc aatgagccaa tataatggaa atggcttttt
     3121 tgctccggaa agaacacatc cggatttacc caatgctcat gtttttctaa gttccaactt
     3181 tccccatttt cttgattata cagccaacct tcctgtacca ttagctggta catgacaccc
     3241 acaactagat tctctttttt gctgttcata tgaacaaaat gaaattcaat atcttcctgt
     3301 tttccgttga tgatatgttc agaaggcaag tggaaatgaa tatctgtcaa ataatagcgt
     3361 tctttcttga actctacata actgagttgg tcaaaaggta ctaaatgaat cgtgtttttg
     3421 aattccttgt cagtaaaccg ttgcttttga taatgaaagg aaagcgtgtc tccttctatt
     3481 ttggtttctt cccccttggt caaatgaata ggcgactgca atggaaattc cgcacctctc
     3541 gcaaaccaat cacataaact cgcccaattt tccggacctt tgtctccaga atagccccat
     3601 tcgacatcca tattcttttt caactatact tccccctgca tctcatatca tttttatttt
     3661 tcttctttct ttacaatcgt tgagacggtt tctaaaaacg cctcttttcc ataaaattcc
     3721 tggttcaata gttccggaaa tatctcttta aagaaatact gaacagaagg ccgatgttca
     3781 aagcttttaa tcgtagtcac tgcctcaatg aacatctcct tataaacttt ttccgggtta
     3841 tttttgatga tttcatcaaa agattcataa agaaggtcaa ccttatctga aatggctaat
     3901 agttctcctt ctacggtttc atcttttcct tcgaacaacc gacggcgata aacttcttgg
     3961 aactcagctg gaatctcttg gttgatgaat tcgtccgtca tcttttcttc aactgtttgc
     4021 agcatccctc ttaactcttt gcttgcgtat ttcaccggcg ttttgatatc accaataaaa
     4081 cgctctgtgt agtcatgatt caatgatttt tcatagagca gtttccaatc gatcggttgt
     4141 ccattcgctt cttcaatgtc tcctagaact tgcgcaatag atgctacacg atacgaatgt
     4201 gctgcaactg tatgctctgt atatttaaaa aatccaggtg cccttgtgat cgtctctaaa
     4261 ttgttcaatc ctaaaataaa ttcattcaac cccataaaag ttacctccct ttgagatttc
     4321 tttttccgaa tatcatatca ttaaataact gatattcgca acatttccgc tctttaccat
     4381 ttttgaaaca gctcccttac caaaaaatag agaaaatcta tatataatag aaaaaagaga
     4441 agagattatt ctcttctttc tgctaaccag tcttagaaaa atgaatttta aaaaaatcaa
     4501 aaactgatca cgatagaagt ttcttttcat acctgatgaa aagatgcttc tcgcaatcag
     4561 tttttggatt tttgctattc caattgatga ttctggagac acaaatcgga tttctctatc
     4621 ttcatcaagc gcgcttaaat ctgccaattt tcaggatctt ttttccattc ttttagcaga
     4681 gttaattctt gctcatcgat ataacgatct tctaaagctg cttcaatcaa tacagaataa
     4741 ttggtcaacg tcataagagg gatttcggct ttttcgaaat ttgcttttcc ttttggcaac
     4801 tcatacgtaa agatagccgc aacaccaagg atatccgcac cttctctttt tgctgcttca
     4861 gctgcttcca agacacttcc gcctgtagaa atcaaatcct cgatcacaac catcttctga
     4921 ccttcaaata tacgtccttc gatttggtta cctttcccat gatctttcgc cttacttcga
     4981 atatagacca ttggcaaatc cagtatttcc gctacccatg cggcatgagg gattcctgct
     5041 gttgcagttc cagcaatcac ttgtacttca gggtaagctt ctttgatttt gcttgctaat
     5101 ccttttgcga tctcttttcg gacttttgga tagctcatcg tgattcggtt atcacagtaa
     5161 attgggcttt tgattccact tgcccatgta aaaggattac ttggatttaa aaatactgct
     5221 tcaatttcta ataagtcttt tgcgatactt tgttcaacat tcattttagg ttagctccat
     5281 tctgtttgaa tcgtttgata tgctttataa ggattagttg actgagtgat tggtcgacct
     5341 ataacgataa aagttgagcc gatctttttt gcctgagaag gtgtgactac tcttgtctga
     5401 tctcctgcga ctgttccttc tggtcttata cccggagtta agcaaacaaa ttcgtctcct
     5461 gccatttctt tgatcgcttc tacttcccaa gcagaagaaa ccacaccatc taatcctgct
     5521 tttttggcac agctagcata atggatcaca cttttttcta aagaaacttc gattagttga
     5581 tcggcatgca tttcttcttc acttgtagaa gtaagctgag tgatagctag aagtagcgga
     5641 cgttttccac cttctggagt cccctcttct aatcctcgca ttgccgcctc catcatacga
     5701 ataccgccag cggcatgaac acaggtgaga tcaacaccaa gctttgccaa tccccgcatt
     5761 gctttttcga ccgtattcgg aatatcgtga agtttcagat ctaaaaatac attatgacca
     5821 gcctctttta gataacgtac gatttcaggt ccttcttggt agaacaattc cattccgatt
     5881 ttcacaaaca atttttcttc tttcgggaaa aatcgaagaa agtcttctac ctcttgccta
     5941 gttgaaaaat ctaatgcaat aattggtcgt tggtctagtt gattcatcgt tcacgttcct
     6001 ctctcacttc tttgattaat ctttccagcg attcgatgcc tagttcgctc attcgcacag
     6061 ggagctcttt aattagttta ggacagatat acggatcggt gaaattcgcg gtccctatag
     6121 ctacagcact tgctccagcc ataaacatct caagaacatc atccactgtc tgcacgccgc
     6181 ccatcccaat gattggaagg ctggatatac ttgctacttg gtgaatcaaa cgaatagcga
     6241 caggcttgat tgctggtccg gagagtccac ctgtttgatt ggctaaaatc ggttttcttg
     6301 tcttaaggtc aatccgcata ccaagaagag tattgatcat cgtaaaccca tctgcccctc
     6361 cagcttcgat tgcctgagcg attggaacga tgtctgttac atttggggac aatttgacat
     6421 agacaggaac agaagaaact ttctttactg cttgtgttaa ttgaaaagca acatcagaat
     6481 ctgttccaaa agcaattccg ccatgtttga catttgggca agaaatgttc agctcgattg
     6541 ctttcacatt tggtgcttcg ccaattttgc tacaaacttc tacatagtct tcttcacaag
     6601 caccagcaac atttgcgatg atgggtaact cattgtactc ctctaattct ggaagaagtt
     6661 tatgcataac aacgtctaga ccaggatttt gcaaaccaat tgcattcaac atgccagatg
     6721 gtgtttccgc cactcttggc gtgggattgc caaagcgggc atttggagtc gttgccttga
     6781 ccatgatcga tccaagctga ttcaaatcat agtattttcc gtattctttg ccaaaaccga
     6841 aacagccgct tgccggcatg ataggatttt ttaattctag gccaggaagt ttgaccgcta
     6901 aaggattctc attcatataa ttacctctcc tattttaaaa atcggtcctt cgtcacaaac
     6961 tttcacactt tttgttcctg tttcatcttc cggcgtatga caaacgcaag catagcaagc
     7021 ccctatccca catgccatgc gggattctaa tgataactgg acattttgat gcgaagaaaa
     7081 cagctgttcc actgtcttca ataacccgtt tgaaccacat gcaaaaacag ctgtaggttc
     7141 cgtcttcgtt cctaacaata aattaccgac atttccgtgc ataccgtatg ttccatcgtc
     7201 agtagcgatt cttgtttctc ctagacgatt aaattctttt tcataataaa cgacttcatg
     7261 tgtggcaaaa cctaaaaaat gcgttggctt aattcctttt tcgactaact gttttgataa
     7321 ctcatataga ggagggacac cgattcctcc accgattata aatacttcgt ctcctgtatg
     7381 aagattggac aaatcaaaac cattgcctaa aggacccatg acatctaaat ggtctccggc
     7441 agaaagagta gagaagactc tagtcccctc accttccacc cgataaatga tacggcaagt
     7501 atttgtttcg tggtcgatat gattcaagct aatcggtcgg cgtaatagca agtctgcacg
     7561 cggcacgaga atatgcaaga actgtcctgg ttgctgcatt tcttttacta gatcaccttt
     7621 caatgtcatt tcaaaaatct ttggtgccag ctgtttttgc tgaacgattt ccatcatttc
     7681 ttgtttcatc tgtcccctcc tgcaacggtt tttcgtcttt ttgtcttaac atgtgctcgc
     7741 cgttaaatag ggttagttga aaaagcacgg gattccatca ctcgaacgat cgcatctgct
     7801 gtgtctaaag aagtaaacaa tggaatacca tgttcaactg cttctcttcg gatgatgaaa
     7861 ccgtctttag aagcatttcc ccgatcttta tcaatcgtat tgacaaccac ttgtgtttta
     7921 ccatctctta ttaagtcgac tacatttttt tctgctgctt cctcagaaat tttcgctact
     7981 gtttcaacga ccagaccatt tttttcgaaa taagcagctg tatgtttcgt tcctatcaga
     8041 ctatagccaa tttctgtaaa acgtttagct aattctagtg cttcttcttt tgtttcgtcc
     8101 gcaatcgtaa ataatacggc tccatattca ggcaagtgta atccagaagc ttcgaatgcc
     8161 ttgtacaaag ctttgtctaa ttgtctgtca gatcccatta cttctccagt cgatttcatt
     8221 tcaggcccta agtaagtatc aactttctgc aatttcgtaa aagaaaagac aggtgcttta
     8281 acatgaactt cttttgtttc tggataaagt ccgttttcat aaccaagtgt ctttagtttc
     8341 tctcccaaaa tagctttcgt cgcaatttgt gccattggaa ttcctgtcac cttacttaag
     8401 aatggaacag tccgacttgc tcgaggattg acttcgatca cataaacctc attttcatgg
     8461 atgacaaact ggatattcat catcccgaca caattcaaac ctaatgctaa gcggatcgtg
     8521 taatcttcga tcgttttctt gatcgattca gataatgttt gaggtggata cacagccatt
     8581 gaatcccctg aatggacacc agcacgctca atatgctcca tgatccctgg gatgagtact
     8641 gtttcaccgt cacaaatcgc atccacttcg cattcaccac caagcaagta acggtccact
     8701 agtactggat gttctggaga tgctttcaca gcatgttcca tgtaatcttc taaatctcgc
     8761 tggttttcaa cgatttccat cgcacgtccg cctaatacat agcttggacg aacaagaact
     8821 ggataaccaa ttctcgaagc gataaccacg gcttcttctt tacttgtagc agtatcccct
     8881 aaaggttgag gaatatccaa ctctttcagc gcttgctcga ataaatcacg attttccgca
     8941 cgatccaagt cttcgatcgt tgtccctaag atttttacac cagcagcagt caaaggttcg
     9001 gctaagttga ttgctgtctg accaccaaat tgaacgatta ctcctatcgg ctgttctagc
     9061 tcgatcacat tcatcacatc ttcgaaggtc aatggctcaa aatataattt atccgaaata
     9121 gaaaagtcag tcgaaactgt ttcaggattg ctgttcatga tgattgcttc gtatcctgcc
     9181 tgctggattg ctttgacaga atgcacagtc gcatagtcaa attcaacccc ttgtccgata
     9241 cggataggac cagatcccag tactagaatt gagggctttt ctgatcgtga actttcattt
     9301 tcatattcat aggaactata aaaataaggt gtttttgatt cgaattccgc tgcacaagtg
     9361 tcaaccatct tatatacagg aatcaaatca ttttcttttc tcatctggcg aacggcttct
     9421 tcgtttattt cccacagctc cgccactttt ttgtctgtaa aaccgttttg tttcgctgtt
     9481 ttcaatatct tgtcatccaa cggctgctgt ttcaactgct gttcgatttc tacgatatgc
     9541 aacagtttat ctaaaaagaa taaatcgatt tttgtcaaat ccgctaattc ttctatggtg
     9601 taccctcttc taatagcttc agctacataa aacaggcgat catcttgtgc tcgaaccact
     9661 ttttggatta ggtcatcgtc cgtgatgtct gccaactcag gaagttcgat atggtgtgta
     9721 ccgatttcta aagaacgcac agctttcaat aaagactctt cgatattccg accgatagcc
     9781 atcacttcac cagttgcttt catctgcgtg cctaaaagcc gttctccgtt ttcaaactta
     9841 tcaaacggcc agcgaggaat tttagctaca acataatcta atgcaggttc aaattctgca
     9901 aaagtcgttc ctgtaacagg atttttcatt tcgtctaatg ttaatccaag cgctatttta
     9961 gcagctagct tagcgatcgg atagccagtc gccttacttg ctaacgcaga tgaacgagaa
    10021 acacgcggat tgacttcaat cacataataa ttaaaactat gtggatcaag agcgagttgg
    10081 acattacagc ctccctcgat cttaagtgct cgaataatcg aaagagaagc atcacgaagc
    10141 atttgatatt catggtcaga caatgtttga ctaggggcaa atacgataga atcacctgta
    10201 tggataccca ccgggtcaaa attttccata ttgcagacaa cgattgcatt atcagccgaa
    10261 tctctcatca cttcatattc aatttcttta aaacctgcaa tacttcgttc aatcaaacat
    10321 tgggtagcgg gggaaagact taatccattt tctgatacga tacgtaattc ttcttcattt
    10381 tcacacatac ctccaccagt tccgcctaaa gtaaaggctg gacgaacgat gacaggatag
    10441 ccgattttat ttgcaaaatc tacagcttct tctactgtat tgacgatttc agactcgggg
    10501 attggctgat tcaattcttt catcaactgt ttgaatagat cacgatcttc tgcttgatcg
    10561 atcgcagaaa gctttgttcc tagaagttct atgttcaatt cttctaaaat acctgatgct
    10621 gccagctcca ttgccatatt gaggcctgtc tgtccgccta aagttggaag gagagcatct
    10681 ggacgctctt ttcgaagaat ccttgataca aattcaagtg tgatcggttc gatatatact
    10741 tgatctgcca cttctttatc cgtcatgatc gtcgcaggat tagaatttac taaaaccact
    10801 tcatatcctt cttcttttaa ggcaaggcag gcttgtgttc ctgcgtagtc aaattctgcg
    10861 gcttgaccaa tgatgatcgg accagatcca atcaccataa ttttcttgat atctgtacgt
    10921 ttcggcatct gtttactgct cctttcctgc gtccatcatt tccataaatt catcaaataa
    10981 atgtagtgca tcatgcggac caggggcagc atctggatga aactgcacac tgaaagcggg
    11041 ataatctctg tgtttgactc cttctactgt tccgtcattt acttctacat gagttacgat
    11101 gagtttttct ggatcaatcg tggcttcatc gactgcatag ccatgatttt gagaagtaaa
    11161 atcaattctt ccggtcgcta cttctcgtac cgggtgattt aatcctcgat gtccgaattt
    11221 cattttatag gtatctgcac cgttggctaa agcaaataac tggtgaccga gacaaatacc
    11281 aaaaatcggt acttttcctt ggattttttt gatcatttcg attgcttctg gcacatcttt
    11341 tggatcacca ggtccattcg tcagcatgac tccgtctggt gatagcgcta aaatcgtctc
    11401 ggcatctgtg ttatagggaa gtactgtgag gttacagttt cttttactca attctcgtaa
    11461 aatactatgt ttcaagccga agtcaatgac aatgactttc cgacctgttc ctggacttgg
    11521 ataaggtttg ttagttgaga cttgctgcac ttgattggtt gctagaacgg ttgctttcag
    11581 ctgatcaaat gcatgttcga aggaatctcc agcatcaact atactagctt tcatcgttcc
    11641 gacttcacgg attttgcgag taagggcgcg cgtatcgata cctgatattc caggaattcc
    11701 tttttgtttc aaaaatgaat ctagcgtcat ttggtttcgc cagtttgaag ctacacgtgc
    11761 atgttctttt actactactc ctttgcatgt tggagaaatc gattcataat catctctatt
    11821 taccccataa ttacccacca taggataggt aaatgtaatg atttgaccgt taaaactttg
    11881 atcagtgata gtttcttgat aaccagtcat acttgttgta aaaacgattt ctccgaagac
    11941 actagcatct gcaccaaaag cctttccttc gaaaactgtt ccatcttcta atataagcaa
    12001 acgttccata cttttattct cccttctgcc acacaagttt tccgttgaca aaagtcattt
    12061 gtgtttcgcc ttttactttc cagccgataa aaggtgtatt ctcccctttt gataaaaagt
    12121 cttctttatc gatcgtgcaa gtttgtgtaa tatcaaaaac tgctacatca gcgggggcac
    12181 caaccgttag cgttcctgca ttcaaaccaa aaatctcagc cggtttaact gccaaccaat
    12241 tgatcacttg ttccaacgtg aatcgaccag tttctacaaa atgagtatag atcagttgaa
    12301 acgctgtttc gcttcctacg ataccaaatg gtgatttcat gaaactttgg cttttttctt
    12361 ctaatccatg gggggcatgg tctgtagcga tgcaatcgat cgtaccgtca agcaagcctt
    12421 cgatcaaagc ttctctgtcc tcccgtcctc ttagcggcgg gttcattttc caaaagccga
    12481 aatcttcggg aatatcttcg tcgatcaaaa taagatgatg gggtgaaact tctgctgtta
    12541 cgtggattcc tgcttttttt gcgtctctga ttacacggac actttcttta gtagaaacat
    12601 ggcaaacatg gtaatgaaca ccagttgctt cagctagcaa cagatctcta gcaatttgag
    12661 aagactcggt tacgcttaag atcccgggaa gaccaagttc ttctgccttc ttgccagcgt
    12721 gcataacgcc gccaaataat aaagattcat cttctgtatg ggctactagg gctttattgt
    12781 tttttgcagc ttctttcata gccagataca tcgtcccagc tgtttggaca cctacaccgt
    12841 catttgtgaa agcaaaagca ccttcttcaa tcagtgcttc ttgatcaact aatttctcac
    12901 ttcgcagatt ttctgtgatt ggcgcatact gcaatacctt cacaactgca tcttttctaa
    12961 tgatgtcata tacttgtctc agcttttctg ccgtatcagg tacaggattt aaattcggca
    13021 tcgcgcatac agtagtgaaa ccgccacgag cagctgagcg agtcccagct tcgatcgtct
    13081 ccttgtatgt aaatcctggc tctctcaaat gaacatggac gtccactaaa ccaggtgtga
    13141 tcaattgtcc ctttgcatca aacacttcat caaattcggc ttctgagaat cctgtaccga
    13201 ttgctttgat tcgcccatct tctatccaaa tttctgctgg tgtcgtcata ttttttcgtg
    13261 tattgatctg accgttttta atgagtgttt tcattttttc atcctcctat aattacgctt
    13321 ttccatttag cactgcttct aagattgcca ttctgacgaa tactccattg ctcatttgct
    13381 gaacgatccg cgactgtaat ccttccacta atgaatcagc taattctaca tcacggttaa
    13441 ctggtgctgg gtgcataatg attgcatgtt tttgcaactt cttcgcacgc tcaactgtta
    13501 acccatgttc ctgatggtag ccttcttttg agaaactttc ttttccatca tggcgttcgt
    13561 gttgcacccg aagcatcatc atgacatcaa cttgatctag tagttcatcc aatggcatat
    13621 aatgtccgta cacttcgaat tcatcgtcgt accattctct aggacctgag aagaatactt
    13681 gtgcgcctag acgttttaac atctgcatat tggatttagc tacgcgagag tgagtgatat
    13741 cacctacgat ggcaactttc agaccttcaa aatgaccaaa ttcttcataa atggtcatca
    13801 aatcaagcaa gcattgggtt ggatgctgtc cgcttccgtc tcctccattg ataatcgaac
    13861 actggattgt tttactttgt atcagttcgt cataatagtt ctcatcacca tgacggataa
    13921 ccgctacgtc tacgcctaat gctgacatcg tcagtactgt atcgtatagt gtttcccctt
    13981 tttggacaga gcttgtgctt gcttcaaatt caatcacttc tagccctagt tttttctccg
    14041 ctacatcgaa gcttttatgt gtgcgagtac tattttcgaa aaagaggttt gtagcaaagt
    14101 actggcgctt ttgcggagtc caattagcac cttgcttgaa ttcctgccct ctgcggatca
    14161 agcccataac ttcttgatca gtaagtgcct caacggtcaa taaatgcttt aagctgatac
    14221 gttctgattt gatgatcata atgtttcctc cttagttttc ttcgcttcgt gaagtttctg
    14281 gtaagataag atttaaaatg atgccaagta cagttgctaa tgccattgcc gacaatgtaa
    14341 atgtgcctac ttcaaagacg agtccgccaa ttcctactac taagataact gaagcaatca
    14401 acagattttt ctttttatca aaatcgattt tgttctcgat taaaatcttc attccacttg
    14461 cggcaattac tccaaataag ataaaactga ttcctgagat gactggtcca gggatactta
    14521 aaatcaaagc gcttaatttt cctacgaatc ctaaaatgac tgcaaatact gcagctccac
    14581 cgatcacaaa cacgctatgg acacgtgtga tagccagaac accaatgttt tcaccgtaac
    14641 ttgttacagg aggacctccg acaaaggctg ccacgatttg tgctaatcca tcacctgtca
    14701 acgtcttatg aagacccggt tcttcaaaga aattacgttt agttagttta ttcaatacca
    14761 taagatggcc gatatgctct gtcatcgtca caaaagcgat gggtgccatt gttgtgattg
    14821 ctccaagata tagctttggt tcatattgta caaagggaat ctcaaagtta ggaacagcaa
    14881 accaggcagc gtctacgatt ggcttagtat ccacgattcc aaacagcaag gctacgatgt
    14941 atccgctaat aatacctagt aaaatcggaa tcaatccgag aaaacctctt agccacatgt
    15001 tgaagaaaat tgttaatcct aatgtgatca gcgctacagc aatatacttg aaatcatacg
    15061 tgccctgatt atacatagca tttgttgctg catttgccgc aagtcccaac ccgataacca
    15121 tgatgactgg accgacgacg attggaggca agattttatc cagccatgct gaaccgatct
    15181 ttttgatgat cagcgcaaca atcaaataga ctaatccagt tgtgactgct ccttgtgcaa
    15241 tcgctggata accatctgtt ttcatcaaaa gctgcatcgc tgcaatgaaa gcgaagctgc
    15301 ttcctaagta cgcaggtatc tttcctttag tagtaaataa gtacaccaat gtacctagtc
    15361 ctgaactgac tagcgcaata cctggatcga tacctactaa gatggggact aacacggttg
    15421 ctccgaacat cgtgaacaag tgttgtaaac ttaatcctac ccaatgtcct ggggttgggc
    15481 gatcgtggat atctaacacc acgtcatcat tatgaaatcc ttttttctcc gacatgtttc
    15541 tctctcctct aatcttcctc tttcaaaatc atgatgcgat cttgtccatc aagctcttgc
    15601 atctctacta aaatctcttc cgcccgagat gttggaatgt tcttcccaac ataatctgca
    15661 cggattggca attctcgatg cccacgatcg accaggactg ctaatgaaat ttttcttggt
    15721 ctgccaaaat ccattactgc gtccattgct gctcgaatcg ttcgtcctgt atacaaaaca
    15781 tcatcaatca aaataacttc ttttccttct aaggaaactg ggatgtcaga agaatgaagt
    15841 tccggttctt ctggattttc ttttttgtca tctcggtata aagtgatatc cagttctcct
    15901 acaggaatat cgatatcttc tagctgcttc aggcgttcgg caattcttga tgcaatgtag
    15961 attcctcgtg ttttgatacc taccaatacg atatcttgga tactatggtt tctctcgata
    16021 atctcataag taattcgagt caatgctcgc ttcatggtta cctgatctac tacttctttt
    16081 gcttgcattt tcattccccc tacttttttg cataaaaaaa ctcctgccct aagaggacag
    16141 gaggaatgtt tagactgagc gtatactgat acactgatag ctatactatg tcaatgagca
    16201 atctacttat ggcgcaccat acgtatcctt gctcccaccc ttcttagcct cacgggacta
    16261 aacttaaagg aattctatta agttttatgc tttcgttgtt aattactata ccgttatcta
    16321 aattaaaatg caatgttttt tcttaatttt tctaaagttt tttcaaaaac ttctggaaga
    16381 ggtgcttcaa agatcatctt ttcgtttgta gtcgggtgcg taaaacctaa catttgcgca
    16441 tggagaaact gaccattgcc tttcaaagtt ttcttcggtc cgtatactgg atctccagct
    16501 aacggataac cgatatactt catatgcaca cggatctggt gtgttcttcc ggtttctagt
    16561 tttaattcaa ccagagtaaa tccttcgaaa cgttccaata cagtaaaatg tgtgacagcc
    16621 gacttcccat cttctcttat cgcctgcatt ttccggtttt ccttcgaacg gccgattggc
    16681 gcattgatgg ttcctttttc gtgaggaatc tctccatgga ctaaagcaac atatttgcgc
    16741 aaagaggtct tatcttttaa ttgctgagct aatgattcgt gtgcctggtc atttttggca
    16801 accattagca gtccggaagt atctttgtcg attcggtgaa caatacctgg acgaataacg
    16861 ccgttgatcg tagaaagatc cttgatatgg tacatcagcg cattgaccat tgtgccatgc
    16921 gtatgacctg ctgaaggatg aacgaccatt ccttgaggtt tgtttatcac cgctacatct
    16981 tcatcttcgt aaacgatcgt caacgggata ttttctggga ccacatctaa tgtttctggt
    17041 tcggggatca agacagtaat ctcgtctcct tgttttactt tgtaatttgc tttgactggc
    17101 tgtccattga cagaaaccgc tccatttttc agccacagct gaatttgcga acgactgtaa
    17161 tcggtgaata aattagtcaa tactttatcg atcctaccag attcatggtg aatcgtcgtt
    17221 ttaagttctg tcattttttt ctttgatcct tttcatctaa aataatataa attaacatac
    17281 aaatcactcc acatacaagt gtcacatctg ctacgttaaa aatcggaaag ctcataaaat
    17341 ctgtctggaa catatctact acatagccaa gacgaatacg gtcgataaaa ttgccaatcg
    17401 caccagctag aatcaaactc aatccaatca tgaaccagcg attacctttt tcacgatttt
    17461 taatcatcaa tgtgagaatc acaacgactg caatgagtgt cactatagta aagaaccaca
    17521 tcttcccttc tagcatactc catgcggctc cagtgtttcg aatatgattc agtgacaaaa
    17581 tacctggtat aagatttttc gtctctccaa gcgctagatt atcagtgatc caccatttga
    17641 ccaactgatc cactcctact agcaaagcgc tgaatatcca ataaataatt aacaaaaaat
    17701 caatcctttt ctatttgttt ataaatatca cgaggtcgta cgatcccgag cagattacca
    17761 tcgggattcc catctttagt gataagtacg gcttccaaag tcccttgctc acgaaacatc
    17821 gcttcaacct cgtaaatatg tgttttagct ggaacaaaat gataatttgt gtactttccg
    17881 ttttggatga tcaaatccaa cgctcgttta tttgttaaat caaccggacc tttttggctt
    17941 tcttttgcta gccaaaaccc gatattacgt aaagtaatca atgctacaaa ttttccttta
    18001 ttgtataacg gaaattgtga ataccttttt tctgctacta tctttaacag ttcaagtaac
    18061 ggaagatctt gttcaaaacc tgttacacgt tttgcaaatc gaggcagcac ggtttcaggc
    18121 tgaatcagtt cttgttcgat cagctggatt cgcttgactg tccaatcatt tggctctgca
    18181 atgacaaaat cgactgcgat ccgatcatgg acgatcgcat tccttaactg agcaagctgt
    18241 aaaagatcat cttcgtattt tctgatcatt aattgttttc tttgagctag gcgtctgaca
    18301 agttcggtaa atcccatatt tcgtgcattt cccatctcgt ctctcatcca tttttcgatt
    18361 cgattgaaac tgattaaaaa aagatcagag tttgccataa ttttcctcct tgatcaaata
    18421 tgcccggttt tttatataga aaaagaacgc aatcaacaca ataactgcaa aaaaactgaa
    18481 aaataaattt tgtaggaaaa cggcccccaa cccagttgct agaaataaaa acggatagat
    18541 ttgaagaatc aagtaattca ttgtgatcac ataagcaggc tttgcttctt tcactgtata
    18601 aacggggctt tttagccaat aaaaggtgac ctgcatcgta aagggcactt ccagatcaag
    18661 cgttatcttt tgttcatgac tgagaacact gcgtttttca ttgttgattc ttagctgaat
    18721 cgagctaccc ataccgtaaa aaccggtttt tcttataaat gtcgttttca tcataccctc
    18781 ctattatgct ttagtatagc tcaaaataca ataaagaaaa agaatgatcc tagtgtaaac
    18841 aaaattaatt ccctatcgtc taaaaaaaga agctgtagtc aaaatacagc tccttcgatg
    18901 gtagattata atcaagctta aaacaatccc aacacttctc cgtcatttgt cacgtccata
    18961 ttcaatgcag caggtttttt aggcaaacca ggcatcgtca taacatctcc agtcaaggct
    19021 actaaaaatc ctgcccctaa ttttgggatg atttcgcgga tcgtgatggt gaaatcttcc
    19081 ggtgcaccta gcagtgaagg atcatcagaa aatgaatact gtgtttttgc catacaaatc
    19141 ggcagtttgt cccatccatt cttcgtaaac tcttctattt gtttttgcgc ttttttgctg
    19201 aaaacaacac catttcctcc gtaaattttc ttgacgattg tttctgtctt ttcttgtatc
    19261 gtttcttcta ggcggtataa tggcttgtaa ttagcttctt ttctatcaat caatcgtact
    19321 acagcttttg ctaaatcaac gccgccttct gctccatctg cccatacact cgctctcttg
    19381 gcaagaatcc cctgattttc acacaagtgc tccaacagtg tgagttcatt gtctgtatct
    19441 gttacgaatt cattgattgc gacgatcaca ggtagctgat attgttccat attacgtata
    19501 tggcgcttta aatttgcaaa acctactttc aaagcatcaa gattctcatt tttaagttca
    19561 tcttttttca ttccgccatg cattttcaat gcacggacag tggcgacaat caccacagca
    19621 tccggcgctt ttttcaagtt aggtactttg atatctaaaa atttctctcc gccaagatct
    19681 gcaccaaatc ctgcctctgt gacaacgtaa tctgctaatc tcaatgctgt cttggtagct
    19741 aaaatactat tgcagccatg agcgatattg gcaaacggtc ccccgtggac aaaagctggt
    19801 gttccgtaaa ttgtttgtac aagattcggc ttgattgcat ctttcagcag taatgccaga
    19861 gcgccttctg ctttcaagtc tccagcagtc acaggctgac ggtcaaatgt atagccgaca
    19921 acgatccttg caagacgagc ctttaaatct tcaaggtctg ccgcaagaca caagatagcc
    19981 atgatttcgc tggcaactgt gatatcaaac ccatcttctc ttggaacacc ttggattggc
    20041 ccacccaagc caacaattac tttacgcagt tcacgatcat tgagatcgac tacccgtttc
    20101 caaatcactc ggcgggcatc gatgttcaat tcatttcctt gatgaatatg attatctaaa
    20161 agagcagata atgcattatt agctgttgtg atagcatgca tgtcaccagt aaaatgcaag
    20221 ttgatatctt ccataggcaa tacctgtgca tatcctccgc ctgcagcacc acctttgatt
    20281 cccatcacag gaccaagtga gggttctcgc aatgcaataa cagatttttt attgatttta
    20341 ttgagcgcgt ctcctaaccc tacagtgatc gttgactttc cttcgccagc tggtgttgga
    20401 ttgatggaag taactaagat caaatgcccc tcagcgttat cctttgatcg attgattcca
    20461 gaaaaattga ttttcgcctt atatttccca tacagttcca aatcgtcttc cttaagatct
    20521 aatttactag ccacttcaac aatcggttct agctctgttt cttgtgaaat ttgcagatca
    20581 ttcttcattt gattacccct tttcacgaac tttattcaac aaaatatctt ctttgttaag
    20641 atatgccaat tatacctttt tttattcaga aaaaaaacat aaaattacag gtttttaatt
    20701 tatttgacgt acttataaat actctttata atgaaggcta tgatcagact ttagaaaggt
    20761 cgtgagtgct ttgaccacag gaattgtaaa atggtttgac aacaaaaaag gatacggctt
    20821 tatcagttat gatgacacag aagaaatttt tgtacatttt actgcgattg aagaagaggg
    20881 attcaaaact ttggaagaaa atcaagtggt cgaatttgag atcatcgaag ggaatcgagg
    20941 aacacaagct gcccatgtca agaaaggcaa cgttcagact accgatacta gtatgcatga
    21001 atagataaac aaatagagtg agacgctaaa cgggatgaac cgtacgtctc actcttttct
    21061 tttcctgtaa aaattcgttt ttttaggttc tgatttttaa aattagcttt ttcttttttt
    21121 cgtataagga taaggaattg attctgattt gggtccgttt ttttcaaaat gatcaaaaag
    21181 gactacttga tctttttttc gcatcatgaa aacagatggg gctttctcat cttgcaacat
    21241 catttgcacc ccagtattag ttggcgtcaa agatcgaatc tgtccgacag atatttctcg
    21301 gtctttccaa aaagcagcat aacgtataat cacagagttt gattttaaaa taaaagaacg
    21361 ccgcaaacct agaaatagaa aaacaagaaa aatacctaaa acaaaattgc ttttccaata
    21421 aggacctgtg ttttctaaag aaagaatcag actaaaaaac agaatgatca aggtcaatga
    21481 ccaatagatg atcgtatgtg ccagttcagg ctgccatcga atattttttt tcattctcta
    21541 acctctcacc gattcagtaa tgatataatc ttaccataac attagtttga acaaaaagga
    21601 gaatctcttt ttatgttaaa agtatacatt gatgcctcta caaaaggcaa ccctggtcct
    21661 agtggaggtg gaatcttgat tgtctatcaa ggtaaacaag aacagctatc tatcccgctt
    21721 tctataggga caaaccatca agcagagttc gaagtctttt taaaaacttt agaatttcta
    21781 aagaaaaacg acttacagaa tgaaacgatt ttctgttttt cagacagcaa aacactagtt
    21841 tctacggtcg acaaaaacgc aacgaagaac gagctcttcc ttccctacct tcaaagaatc
    21901 caagaacttc tatccgaatt ttctttattg atcctgcaat ggttgcccga aaacaaaaat
    21961 aaaggagcag ataatcttgc acgtcaggct ctccataaac aattaaaaga aaaaaagact
    22021 ctttaaatta aaaactttaa ggagtctttt tatagtttct catttaatat aaaagataat
    22081 tgtgatcaaa cgtaatttcc aattggtaat ctccgatttt ttcttctatt tgactacgta
    22141 agattctttc tagttctgta tcaacaaact ggaatttctc agggaccact acatcaaatt
    22201 gcagcgtttt tccttgatga attactctaa aatcatgaat attaagccct gtacctgttt
    22261 caagaagaat ttgctttaac tgccgcaaga tattatagta tttttcgtta tcaacaggca
    22321 ttggatccaa gtgacagaca agttccacat ccaaagactt tttaaagtct ttttctatca
    22381 gatcaataat cttatgagcc acattcaaat tcattgattc atctacttcg atgtggactg
    22441 atgcaaagcg tttattgggt ccatagttat gcaccaataa atcatgatag ccaagtatat
    22501 catcgcaagc atttaaatgc tcttccattt cttcaatctc tgctggcgtt gggcgacttc
    22561 ctaatagttc gtatacaaaa tttcgaagca tcgtcaatcc actataaagg atatataatg
    22621 ctaaagcaaa acctatatat ccatcaatac gccatccagt tacccattcg attgctgctg
    22681 aaagcaatac agccagtgta gtaaagacat cattataact atctgttgct gtagctctca
    22741 atgtttcaga atcaatggat tgcgcaataa cctgatacat tttgccttgt gcaaatttca
    22801 aaaagatgga aatgattagg acaaaaaaga cgatgggtgt taaagagaca ttttctggat
    22861 ggatgatttt ttcagcagaa gactctaaaa attgaaatcc tacataagta atgatgatcg
    22921 aaacaaataa cccactgata tattcgaagc gttcgtgtcc ataaggatgt tcctgatctg
    22981 ctggctttgc agcaatttta aatccgatca aagtcaatat ggatgaagca gtatctgata
    23041 gactgttcac tgcatcagcc ataatggaga cacttcctga aaaaagcccg atcattagct
    23101 tagagacaaa caagatcaga ttcgtaacca atcctaagat acccgctagt actccttttt
    23161 ttgtccgctg ttgcggtatt tgtttctttt tttcttcttg tttcttagcc aagtttttta
    23221 ccccttctag tttgcttgtt gctcaggtaa aaagatggag aggacgattg ttttcctctc
    23281 ctctcttcct ttttctatct atcgtgcgtc ctattactat taaaagatgg tcattattct
    23341 ggtttcaacg gtgttgctgc aaataacgct tttgctagta atggtgttat gattcccgca
    23401 cctattgctt ctggtatccc attgattgct gcaacccctg ctaaggtttt aaataaaaga
    23461 gcagagtcta caccataggc atctgccgtt gcacctgtat aaaataatcc catgaatcct
    23521 aacactaaga ctgtattgac caatgaaccc agtacccctg caaaggctga gctgatcgtt
    23581 attgatttat ttttttgata aatccagtgg aaaaccaagc ctgctactaa gccaacaagt
    23641 actctgggaa ctaccgagat aatcggattc gtgaacacta atgtatcaaa tggcgttgtt
    23701 ggcatggcat aggcacgaac aattgtagcg attccccaaa acaagccaat caccatgcca
    23761 tcttttgggc ctaatactac tgcagcaata attactgtga tatggataat tgttaaacta
    23821 atgaatccta atggaataaa ccccagccaa ggaaccatcg cttgtacgat gatgattgct
    23881 aacaagatcg cacgtaagac tagtcgaaag gtcttatttc tactattcat tttttcaccc
    23941 ctttttattt atactaatcg taaaaatttc tgtcactttc gtcaactaaa gaccatccga
    24001 atccgaccat ttgattagat gcgccatcca attgaaaaaa gtatgagggc aagacttgtt
    24061 tgtcttcgcc cccataatca tgtttcgttc aatgtttgaa cttttgtttt tctgtcaaac
    24121 gtaaacgccc tattgttgcg caacccattc tttcgcagct ttaagtgcat ctggaatacc
    24181 agcaggattt ttcccgccag cttgtgccat gtctggacgt ccaccaccgc caccgcctac
    24241 tttcggtgcg attgctttaa tcaagtcgcc agcttttagt ccagcttcat ttgattcttt
    24301 cgtcattgcc gctagcagac tgacttttcc ttcttgttcg tttgctaaaa caagaatatc
    24361 tgaaatattt ttttgtttcc attggtcagc taattgacgc agctgattca tatctttcac
    24421 ttttacttgt gctgcaatga ttgtttttcc attgatcgtt tctggatctt tgaatacatc
    24481 accagcttgt tgattcgcta acttgctagc taattgttca ttttcctttt gtagctctct
    24541 tacttgctgt tgcaattgtt ccgcttttga aacaacttct ttcaattgag gtgatttaac
    24601 aattgttgct acttgtttta gttgtttttc ttcttcttca agtagttcgt acgcttcttt
    24661 acttgttaca gcctcgattc gtcgcacgcc tgcaccaatt cctgattcag aaacgatttt
    24721 gaagattccg atgttttctg tatttgctac atgtgtgcct ccgcacagtt cgattgacca
    24781 gccgccaata tttactactc gaacgtcatg tccgtatttt tcaccaaaca aagccattgc
    24841 acccatgttt ttggctgtat cgatatctgt ttcaattgtt tcaactggga tagcttccca
    24901 gattttttcg ttgacgattc tttccatttc agctaattca tctgaagtga tttgaccaaa
    24961 gtgggtaaag tcgaatcgta aatgtccagg agcgactaaa gaaccagctt gatttgcatg
    25021 ctcgccaagt acttctttca atgccttgtg cagtagatgg gttgctgtat ggtttttgat
    25081 gatccgattg cgcatcgatt gatcgatcaa tagatgatag gtttgtcctt cactcattgg
    25141 tgcttttact tctacggtgt gcataaattg accattaggc gctttttgaa catctgtaac
    25201 aactgctacg atttcgccta cttcattcat gatccatcct tgatccgcta cttgcccacc
    25261 catttctgca tagaaaggtg tttgatcaaa gatcatttga gcttcacctt ctgcgacttc
    25321 attcaaaaga gactcacctt taacgatgac caataattga ctatctgatt cttgttctgt
    25381 gtatccaatg aatttacttt ctactttgat atctgtcaat aaagcagatt gtacccccat
    25441 tgatttttca gtactgcggg cagagcgagc acgttcgcgt tgtgcatcca tttctttttc
    25501 aaaaccagca tgatcaactt tcagtccttc atcttctgcc acctcttccg ttaattctac
    25561 cgggaagcca tatgtgtcgt atagtttgaa gatgtctttt cctgctagag tcgtcccgtt
    25621 ttcgtttttt acttcttgga tcacttgatt taagatttcc aaaccttcat tgattgtttc
    25681 attgaaacgt tcttcttctg tacggataac tttttcaata aattcttttt gttgaagtac
    25741 ttcaggataa taacttacca tgatttcccc aacaacaggg actaaacgat ataagaatgc
    25801 ttgttcaata cctaattttt tcccatgcat gacagcacga cgaagcaaac ggcgtaagac
    25861 ataccctctc ccttcattcg atggcaatgc accgtcgcca atagcaaatg aaagggcgcg
    25921 aatatgatct gcgattactt tgtaagaaat atctgttact gggttttcac catattttac
    25981 ttgtttgctt agcttttcta cggcgtggat aataggcata aacaagtctg tctcaaagtt
    26041 cgttgacgca tcttgaacga ttgagaccat gcgttccaat cccatccccg tatcaatgtt
    26101 tttatgagga agtggttcaa atgtgttatc aggcttatgg ttgaattctg aaaatactaa
    26161 gttccagatt tctaaataac gttcattttc tcctcctgga tagttttcag gatcgtcttc
    26221 tgctaaatcg ttataagctt ctccacggtc atagaaaatt tccgtatccg gaccacatgg
    26281 gcctgcaccg atatcccaga agttgtcttc tacatcaata atgtgatcta gtggcaggcc
    26341 aacttcttca tgccagatgc gttttgcttc tgtatctttt ggataaactg ttacataaag
    26401 tttttctgga tcgaatgcca tccattttgg atcagtcaaa aattcccatg cccagtggat
    26461 ggcttcattt ttgaaatagt caccaatcga aaaattaccc agcatctcaa acatcgtatg
    26521 gtgccgtgct gttttaccga cattttcgat atcatttgtt cgaatagatt tttgggcatt
    26581 tgtgattctt ggattttctg gcacaactga accatcaaaa tattttttca atgttgcaac
    26641 accagagttg atccacaata aggttggatc gttcacgggg atcaaagacg cactaggttc
    26701 aatcgtatgt cctttagatt ggaagaaatc aagaaacatt tgtcgaactt gtgcactact
    26761 taattgtttc atgtcattac ctgctttcta taaattaaat acaaaaaaac accatcacag
    26821 ccaaggacga aaactcgcgg taccaccttg attgcaatga tgtgtaatca ttacctctta
    26881 aactcgataa cgctgagctg cgtcggtatt tctaccaaaa tagaaaaagg gagcaatttg
    26941 attagtgact attctttttt cagccaagaa agaattttct gtgagtctta aaaaacaaat
    27001 catatccttt tcgtacttaa ttagtatacg cattctattg atcactgtca atatctcaat
    27061 ttttattttc atttcctttt ggtcatactc cacgattttt ggtacgataa gaataaagga
    27121 atcaatacat ctctgctatt catgacaagg aggaatatga tgaaaaaaat agttggagcg
    27181 gatgaatgga tacgcgcagc tagctgcttt ttgagatatc aagtttttgt attagaacaa
    27241 gggattcctg cagaactaga attcgacgga aaagatatcc cgcaacaaac ctattatcta
    27301 tttcttgatc aaaaaagacc agtagctact ttgcgttatg aaaagaaaac acctacttgc
    27361 ttcaagccgg aacgattttg cgtagcaaaa gaataccgag gaaaagggtt aggcggtcag
    27421 ttgcttgaag ctgctgaaaa acgggcggtt tcagaaggtt gtcagactag ttatgtagta
    27481 gctgaaatga cggctgtaga tttttatgaa aaacaagggt atcatacttg cacagaacct
    27541 tttattgaag atgaagtact ttgtatcgga atgaaaaaaa gtctagctta aaaacaagag
    27601 attgtgacac gccttttgtc acaacctctt gttttttatt tatgtgaatt tttcttattt
    27661 ttacgagcag tacggctttg ctgtctgcgt tcgattttgc gttctttttt atttttttct
    27721 gcaattgccc aatcgatttt tttcttataa ccaggcttga tctttttctt tttcttcttc
    27781 acaagaccaa tcagcgtggg atctaataca tcttttgatt tttctcgttt ggcacgtcta
    27841 ttacgatcgt atgttttgac gatttccccg tttttgattt cttttggttc aaatgagacg
    27901 cccaattttt ctatcgcatc aatggcttgc tcatcatttg gcgaatataa cgtaatggcc
    27961 gttcctttta agccattacg tccagtacgt ccgacacgat ggataaagaa gtctagatct
    28021 tctggaattt ctgcattaat aacatgagag acaccttcga tatcgatccc tctagcagct
    28081 aaatcagtcg ctacaacata ttgatactcc agattctgta cttgtcgcat cactcgtttt
    28141 ctctctcttg gggtgatgtc tccatgaatc tttgctactt tcaagccttg gtttttcaag
    28201 taatcggcaa tttcatccac atgctgtttt gtattggcaa atacgattgc taaataagga
    28261 tgaccaattg tcagcagttg ataaatcatt tgattctcat ctttaccttt tgttgaaatc
    28321 agccaatttt caatgtcttc agaaataact gcttttggtt tgatttcttc aatgattgga
    28381 ttttccatgt attttcgtaa gaatggacga agtttttctg gaatagtggc agaaaaaact
    28441 aaaaactgca gcttttctgg taatcgactt gcaatttggt ctacttcatt taaaaaaccc
    28501 atatccaatg tcatatccgc ttcatcgaca acaaatgcaa atgcggtgtg aatcttcagc
    28561 gcttgttcat tcatcatgtc taatattcta ccaggcgtgc ctactacaac ctgtggctgt
    28621 tggtgatgca gacgatttaa ttgacgctgt ttgtctgtac cgccgacaaa attcgagaca
    28681 cggatctccg gtgtagaaaa tttagcgatt tgtgtagctg cttcatagat ctgtgcagct
    28741 agttccctac ttggagctgt aataacaact tgtacttcct ctttttctgc attgattttt
    28801 tcaaacaaag gcaacaaaaa cgtatgtgtt tttcctgtac cagtttgaga ttgcccaatg
    28861 atattttttc cttttgcaat taaaggaatc aaacgttcct ggacctctgt gggctgtttg
    28921 aagccctttg cggttaacgc ttcattgata aacggtttga agcggaatat atcaaaatta
    28981 ttcattcgtg cacctcttct ctttaaatta tcacgacttt ggcattataa cacagacaaa
    29041 gcgtttttgc tcagctaatt tcgagaatca tcatcctttg tttggccaat cgtgctaaca
    29101 gtatatgtgt gactagcttt ttcataaaac agaatccgtt tttttctcaa aaatgatagc
    29161 aagatattta aaataaaaat accttgtagt aacaagacac cgagagaaat gaatactgca
    29221 ctcatctgca acaccgtatt cgttgtcgaa ttcatgattt gctgaagcaa ctgccccaac
    29281 cagcttaaac cataaaaaag aaagtacaga tacccgtagc ggatcatcaa tgcttttaaa
    29341 gaaattcgtt cgcggtcttc ttccaccaaa cggatacgca caattttttt gccaagtgtc
    29401 catccattgg ttataaacgg tacaatcata aagtataccc ctacttctaa taaaagccac
    29461 cagatatgag aagtaactgc ccctgaatcg aacgcaattt taaagaaaat cgccgctacc
    29521 aaattaataa gagataaaaa tgtccagtcg atcaaataag cgaccaagcg tcgagtcaat
    29581 gagacagtct ttcctttttc ataagaaagt tcatccattc gtcttcttgt aggaagcata
    29641 aatgtaaata acggcgtaac gacaaaacca atgattccac ccaatgtatt tgtcactaaa
    29701 tcattcacat caaataagcg gtatggtctt gggtagataa aataaagtcc acttagctgc
    29761 gtcaattcaa aaaatagaga aaggcagaaa ctagcaatca tcgttttcat aaaagaaagc
    29821 cggaaataat atcttaaata aatgccaaac ggtatgagta ataaaacatt aaaagctggt
    29881 tccaaaaata cactctgctt cattgccggc aggtaggtac taggttcaga caagaccaat
    29941 accgtgttgt ctctgaaatg ttgccatgaa gcaaataaat gcagctccat ctttggccct
    30001 gtcatttggg caaccgtctc ctttgccgga agtggtaaga tcaccaaaaa atacgcacac
    30061 aataaataaa aaacgaaaga atacaaaata actgcccttg ttactagaaa tgttccatac
    30121 tttcgatatt cataaataaa aaaaacagat gagatcgcta aggctaaaaa tggaaaaaca
    30181 atcagcgcaa aacgaatcgg ttcgatataa cttgccatat gactcctcct tgattctttg
    30241 tatctctctt atcttagcag tcctttgctg tttcaagcaa gtaacgaggc tattatttct
    30301 catttctttc aaagtaaagt aagataaaca caaagggggt gtcgagatgc tgaatatgta
    30361 ctttgttttt ggcgtaccta tttttttact gttcctttat gctacgatcg cttatgtaag
    30421 aaaaagaact acaattcatt atttaggatt tattctcctg attatttcgg gtttcatgct
    30481 agtcttcaat cttcagactt ggcagcaagc acttcttgaa atggataaaa tgactccaca
    30541 tgctttgtct aaagtgcttg gctaccctgt ctatctgatt tggcttccca ttttcatttc
    30601 tggttgcttg gttttattaa atatttatcg cggcgtacgc cgaatagttc agttacgcaa
    30661 atcaaagtaa aagacagaaa tcggttgagc ccgatttctg tcttttactt tgctatttca
    30721 tcgtagacaa aacgacattt acgtgatcaa aattaacgag tacttttgac atttcttcca
    30781 cgtactcctc atttaaataa aatattttgt ttggcagaga agtgcagttc taataaaatt
    30841 cgaatgtttt agctatctac gttttaaata gagataaatc gggataccag caagtgtcaa
    30901 tactatcccc atcgaagcta aaaaggtctg agtgataagc gtgcttgata cgataaaagt
    30961 ccctccaatg attgctacta gtggaataaa cggatacatt ggaactttgt atggtcgaaa
    31021 caaatcaggt tcttttttac gaagaagaat gacaccaaca aagaccatcg tataaaaaat
    31081 ccaaatgaca aagatcagca tatccgttag tgtatcaaaa ccaccgatca tcatcatgcc
    31141 aatagcgatg actagctcta agatacctgc ggctacagga actttagttt tatcatgaag
    31201 tttagcaaag agcttgctaa aaggcaggtt gttttctttt gccataacat aagggagacg
    31261 cattccagta agggtatagc cattgatggt tccataaaca gaaatcaaga taccaactgt
    31321 gaccagtctt ccaccgaagc cgccaaaaat catttttgca acgtcacttg ccgcattgct
    31381 gtttcctgcg actccgtcga tagatgcggt tcttaagaac accgcattta ctaataaata
    31441 aacgatcatg attccgatga ttcctaaaga aattgctttt ggcaaatctt tcgccggctt
    31501 tttcaattct cccgaaatat ttcctacgtg tatccaaccg tcgtatgcga acatcgttgc
    31561 tagcaagccc gctcccaagg ctgagaaaaa tgaaagattt tctcctgctt ggatcggaaa
    31621 cagttggaag tctactcctt cttgtcggaa caaaccgaaa atgacgatca caaacaaagg
    31681 aataagcttg cagacaagcg taatcgactg aaaagcccct ccagctttag aacctaaaaa
    31741 attgatcaac aggatcgata cagcagctgt aacagctacg ggaacaatca ttgactggga
    31801 aagaccaaat agattgacga actgtgtacc gaaaatgatc gacaaggctg ctacatttgc
    31861 tggaaaataa atcacgactt gcgcccagcc caataaaaaa gctgctgtat ttccgtaaat
    31921 ccgttcgata tatttaatca tccctcctgt ttctggaata gcagctgcca gttcagctcc
    31981 tgttagtcct gcacagacag aaatcatacc accgagaaac caagaaaaca tatgcaaact
    32041 ggcggatcct gtaacttctg ctacgcttgc ggctttaaaa aatacccctg caccgatcac
    32101 tgtgcccata acagtcgata aagcagtaaa aaatcccatc gtacgtttta attcattttc
    32161 tatttttact tcttttactg gcgtggcttg atattcttcc atcccttgtc ccctttcata
    32221 ccatagccaa tcccaaaagt ataaaaaact ttttggatgt ggttcttgtt ttataccgtc
    32281 tctaccaatt tttctttcag tttttccaac atatcctttg tcatcacatc taagtcgtat
    32341 ttcggcgaaa agccccattc ctcttgcgca caagaaacat ctagtgaatt tggccaagat
    32401 tctgctattg actgacgtac aggatccaca tcataatcca tttcaaaatc tggtatgatt
    32461 ttttgaatag atgctttgat ctcttccggg tcaaaagaca tcgccgatat attgaaggca
    32521 tttcgatgaa ccaatcgatc aggatctgca ttcatgagtt ttataatggc atcgatcgca
    32581 tctggcatat acatcatatc cattgatgta ccttgatcaa tgaaactagt gtactttcct
    32641 tctttgattg ctgaataata aatatcgact gcgtagtctg tcgtaccgcc tcctggcaag
    32701 gttgcataag aaatcaatcc agggaaacgg acaccacgag tatctacgcc atatttcaca
    32761 taataataat cacatagtag ttctccagct accttcgtta ccccatacat ggttgtagga
    32821 cgctgaagag tatcttgtgg ggtatgatct tttggagtat ttggaccaaa cgcgccgatt
    32881 gaacttggcg taaaaaattt cagctggaat tctctagcga cttccaatgc attgaccagc
    32941 ccagtcacgt tcaaattcca ggctaattgt ggttttgctt ctgcaacagc tgacaaaaga
    33001 gcagccaaat gaatcaatgt gtccacttga tattgttctg ctatgctgcg cattttttcg
    33061 taatccatta catctaggat ctcaaagata tcgtttttct caatgacttc aggcatgcgt
    33121 atatctgtcg caatgacatt ttcactgcct agttcttgac gtagccgtgt gatcaactct
    33181 gaaccaattt gtcctaaaca tcctgtcacc aatacttttt tcatgatgat cctccctgat
    33241 cttttttact actatcttca gatgattaac aatatatgcg tgaacatgtt ctctaatttt
    33301 aaatagacga aaaaactaaa tttagttaaa taatttccat ttcttttcct attttttgat
    33361 aaactgctac tgcttcatca agcatttccc tcgtatgttc cgcagtcggc atatttctga
    33421 tcctgcctgt cccaagaggc acagttggat aaacgattgg tttagcataa atcccatgtt
    33481 cgatcagctt cttagagaaa gtctgagtca ctttttcgtc tcccaaaatg actggagtaa
    33541 taggtgtttc agacataccg atgttatagc ctactttttt caattcttct ttaaaataat
    33601 tagcattttc ccaaactttt tcgacaagtt ccggatgttc ttgcatcaaa gtaatcgaag
    33661 ccaatgcagc tgcagctgca cctggagtta gcgaagtaga aaataggaat ggccgacttc
    33721 tagctttcaa ccagtcgatt agtgttttcg atccagctac ataaccccca acaacaccta
    33781 tagctttcga taacgtgccc atttgcatat cgattttgtc gcttaatcca aaatgcttga
    33841 cggttcctgc accttttcca gttacgcctg agccgtgcgc atcatcgacg taggtgatca
    33901 gtccatattt ttcaacaatc ggaataattt ccggcaatcg tgcaatgtct ccatccatgg
    33961 agaaaacacc atctgtgata tacatgattt ttttatattt cttactttct atcgcttcct
    34021 ttgctttttt ctcaaggtct ttcatatctt gatgtttaat tcggatgatt tttgctccgg
    34081 ataagcggca accgtcaata atagatgcat ggtttaattc atccgataag atagcatctt
    34141 cttttgtcat tactgcagag atagcgccca tattgcagtt gaatccagat tgaaaggcga
    34201 ttgctgcttc tgtccctttg aattctgcga ttttttcttc taattgctga tggattttca
    34261 gcgaaccatt gatcgttcgg actgctcctg ctcctacacc ataagtttcg gttgcttcaa
    34321 tacatgcttt tttcaattct tcgcgattgg caaatccaag ataattgttg gatgctagat
    34381 tgatcatctt ttttccgtct acgatgatac aagcaccatt ttcactttct agtatgtcga
    34441 tcgtattgta taaccccttt tctttcagtt gatccaattc tttctctaaa tacattgtta
    34501 gttctttgga agacattgtc tccacctcca tattcatctg tcttgcagaa cataccaaac
    34561 atatatcgtg tcattcatct acaaagcaag tatgctatat ttttgataac gcttacactg
    34621 attatgagaa ttatttaacc acatttttta tttacagtat ctttttactt tcaaatgact
    34681 tatatagtat gaacaattac cttttagata atgatctatt ttactctacc tgggcagata
    34741 aatataacac aaccattgat agaagccctt tcgttaaaat caattgtatt ctgaatattt
    34801 aatttattta ttgcatagac caataaaaat acataaaatt tccatcttcg tttatcagca
    34861 atttttaatt ttactctctg aatatttctt aaaagtttta cttgttgaat tcgaaaaaag
    34921 gactgtgaca aaagtcttgt cacagtccta ttctt
//
LOCUS       DADVXV010000021        34772 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.021, whole genome shotgun sequence.
ACCESSION   DADVXV010000021 DADVXV010000000
VERSION     DADVXV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.021"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(228..1115)
                     /locus_tag="KB969_000981"
     CDS             complement(228..1115)
                     /locus_tag="KB969_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6868986.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1112..1981)
                     /locus_tag="KB969_000982"
     CDS             complement(1112..1981)
                     /locus_tag="KB969_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6868987.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2118..3404)
                     /locus_tag="KB969_000983"
     CDS             complement(2118..3404)
                     /locus_tag="KB969_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6868988.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3677..4255
                     /locus_tag="KB969_000984"
     CDS             3677..4255
                     /locus_tag="KB969_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6868989.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4255..5184
                     /locus_tag="KB969_000985"
     CDS             4255..5184
                     /locus_tag="KB969_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6868990.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5181..6917
                     /locus_tag="KB969_000986"
     CDS             5181..6917
                     /locus_tag="KB969_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6868991.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="KB969_000987"
     CDS             complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="KB969_000987"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBB6868992.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7813..8322)
                     /locus_tag="KB969_000988"
     CDS             complement(7813..8322)
                     /locus_tag="KB969_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBB6868993.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="KB969_000989"
     CDS             complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="KB969_000989"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBB6868994.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9623..10714)
                     /locus_tag="KB969_000990"
     CDS             complement(9623..10714)
                     /locus_tag="KB969_000990"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBB6868995.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="KB969_000991"
     CDS             complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="KB969_000991"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBB6868996.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="KB969_000992"
     CDS             complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="KB969_000992"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBB6868997.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="KB969_000993"
     CDS             complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="KB969_000993"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBB6868998.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14677..15651)
                     /locus_tag="KB969_000994"
     CDS             complement(14677..15651)
                     /locus_tag="KB969_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBB6868999.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15632..17515)
                     /locus_tag="KB969_000995"
     CDS             complement(15632..17515)
                     /locus_tag="KB969_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBB6869000.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17533..19758)
                     /locus_tag="KB969_000996"
     CDS             complement(17533..19758)
                     /locus_tag="KB969_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6869001.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19873..20907
                     /locus_tag="KB969_000997"
     CDS             19873..20907
                     /locus_tag="KB969_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6869002.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20974..21987)
                     /locus_tag="KB969_000998"
     CDS             complement(20974..21987)
                     /locus_tag="KB969_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6869003.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22065..22253)
                     /locus_tag="KB969_000999"
     CDS             complement(22065..22253)
                     /locus_tag="KB969_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBB6869004.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22693..22821)
                     /locus_tag="KB969_001000"
     CDS             complement(22693..22821)
                     /locus_tag="KB969_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6869005.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22824..24197)
                     /gene="rlmD"
                     /locus_tag="KB969_001001"
     CDS             complement(22824..24197)
                     /gene="rlmD"
                     /locus_tag="KB969_001001"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6869006.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24308..25363)
                     /locus_tag="KB969_001002"
     CDS             complement(24308..25363)
                     /locus_tag="KB969_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6869007.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25373..26803)
                     /gene="gatB"
                     /locus_tag="KB969_001003"
     CDS             complement(25373..26803)
                     /gene="gatB"
                     /locus_tag="KB969_001003"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBB6869008.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26800..28272)
                     /gene="gatA"
                     /locus_tag="KB969_001004"
     CDS             complement(26800..28272)
                     /gene="gatA"
                     /locus_tag="KB969_001004"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBB6869009.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28272..28577)
                     /gene="gatC"
                     /locus_tag="KB969_001005"
     CDS             complement(28272..28577)
                     /gene="gatC"
                     /locus_tag="KB969_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBB6869010.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28683..30719)
                     /gene="ligA"
                     /locus_tag="KB969_001006"
     CDS             complement(28683..30719)
                     /gene="ligA"
                     /locus_tag="KB969_001006"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBB6869011.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30736..32970)
                     /gene="pcrA"
                     /locus_tag="KB969_001007"
     CDS             complement(30736..32970)
                     /gene="pcrA"
                     /locus_tag="KB969_001007"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBB6869012.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33125..34684
                     /locus_tag="KB969_001008"
     CDS             33125..34684
                     /locus_tag="KB969_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBB6869013.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         9518 a         7494 c         6336 g        11424 t
ORIGIN      
        1 tgacaatcag gacagtcatc ggcaatatag cagcaatcac ttctttaaaa ttttttagca
       61 tgtatcctcc tcctttactc tttaagttta ccttaaaatg aaagagtttt cgagcacaaa
      121 cttaaaacgt tatcatttaa tttttctcaa cataaaataa cacacgtccc aaaagtatct
      181 ttttacttgg aaaaatgact ttgaaggaac gcgcttattg tgttttttta ttttacagag
      241 ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa atacgatggc agttggtaaa
      301 gtagcgatga ctaatccagc catgatcatt ccatagtctg gtgtatagga agcacccata
      361 gcagataaaa caagcggaac cgtccgttta tcaggagatt gcaaagctac taagggccat
      421 aaataattgt tccagctact catgaatgtg atgattgcag ccgcggcata ggtattttta
      481 gccgtcggca tatacactct aaaaaaaata cttagttctt ttagaccgtc taatcgagcg
      541 gcttctacta gatcttttgg aaaagattta acattttgtc gaaagaagaa gatcaaaaaa
      601 gcagtgctaa cagatggcag gatgacaacc aagaaactgt tgattcccaa aaccgttccg
      661 ttcaattgtg aaaacattcg atataaaggg atcatcaatg ccgcaaaagg aaccatcatc
      721 gatagcagta gaatattgaa aattaggtct tttcgtttac tttgataaat ctcaaatcca
      781 tatcctgcca ttgacgaaat cagcaatgca aacacagtgg tcaccaaagc gatcatcgct
      841 gaattccaaa gggaacgagt aaaattcagc tcattggaaa acaaattttg aaaattgatg
      901 atcaagttac tgccaatctt tatttttccc gatgtgatat ccacgggtgt attcgtcatt
      961 cccaaaacca tccagacaaa agggaaaatg gaaataaatg ataggatgct taatgctgta
     1021 tactttaata ctgacccaat tgtcgaacga agttctaatg cttgtttttt gacgttgggg
     1081 cgttcgattg tttctttttc taccatattt ttcatcgact ttctcctcct actttcgttt
     1141 ggattatcga caatatcaca ataaaggaaa caataacaaa ggaaactgct gccgcatatc
     1201 caaaattagg cgtgaattta taactcaaat tatagatgta ttgagatagg gtggtcgttg
     1261 catttgctgg tcccccgcca gtaatatttt gtacttcatc aaaaagctgc aatgtcccga
     1321 tcgtcgaagt aatggaagta aacaaaatga ttggttttaa atttgggatc gtcactttga
     1381 taaactgctg ccatttagaa gcaccgtcaa tagatgctgc ttcataaatc tccgaatcaa
     1441 tattttgcat gcctgaaagg aaaaaaatca tattgtatcc agtccaacgc caagtgatcg
     1501 aaagaatgat cagaactctc gcccaaattg gatgagtcaa ccagccaatc ggtgtgtcaa
     1561 tcataccaat gcccaacaac aagttgttta caaggccaga ttgagaaaat agacttttca
     1621 tgatcagaga ataactgacc atcgaagtga tacatggaag aaagatagcg gttcgaaaca
     1681 accctttata tttcaacttt ttatcattta aaaggttgga aataaaaagt gctagaaaca
     1741 acatgatcgg tacttgtaca agtaaataca ggaatgtatt aaaaaaagct tttttaaaag
     1801 ttgcatctgt caacatccgc tgataattac ctaacccgtt aaatgtcata ttgacagggg
     1861 gaccactttg aaaagacgtg atcaaagcca aaaccatcgg aataaaaacc atgattgata
     1921 tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt gaataaatct ttctgcttca
     1981 ttcttttccc tccaattcta tcattgatta tctacatgaa aagacaagaa agacaatatc
     2041 tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct gatgaaaaag cgaagaaatt
     2101 cactttttta ccaccgatca attagccaat tgtgcttcta cttgtttttg tgtatctgct
     2161 agtaccttgt ctgtctcttc tccattgatg attcgatgaa gagcttcagc tacgactgct
     2221 tcaattgcat aggtctcatg tccgtaattc acttctggta tttcagatgt ccatgttgaa
     2281 aaatcgtcaa agatcttttg accactgtaa aattcagaag cttcttgata agcttcttgt
     2341 tcattcgcgc taagcatcgt agatactagt ccgatttctt tcgcaagagt gcccatcagt
     2401 tcttcattcg aagcaaacgt tgcttctagg aaatctttcg ctgaatcttc tccagctact
     2461 cctttgatca cataccagcc agcgccgcca aggttagaag cttgcgcttt ttgcagattt
     2521 tctggaagtg caggtattgg tgcaatcttc cattttccag attggttttc tgctccttgg
     2581 atcgttgaag aataccaagc gccagttggg ctagaagcta ctgctcctga ttgtatcgca
     2641 gttactccag cattccagtc agaggtttgt tcgactagat cttctttcaa aagagtggca
     2701 aacaattcaa gaccatactt taaagatgca ttgtcttgga tcgtgactgt ctccccatct
     2761 tcagatgtat accattctcc tgcctgttgc ataatcatcc ttactcgacc aaggtcagaa
     2821 ggattgactt cagcgatttt ctttcccgtc ttttctttga catctcgcgc tacttgaata
     2881 tactcgtccc acttcagatt ctccatatcc tcttctgtat aacctgcttc tgccatcaga
     2941 tccgtacgat agaagtttgc tgttacgccc gaatcgaaag gaacaccgta tattttatct
     3001 cctactttgt ttaccgcaaa tttatacggt gcaaaatgat cttcctttac aatagcagac
     3061 aaattagcga atgcatctgg ataagaagtc aaatagcctt gtatcctata atcttcaatc
     3121 aagacgatat tgggcaatcc ttctgtattc ccgctcgcta aagcggtgtt cagtttctga
     3181 acgatatcat cctgagacat cgtaacaact tctatctctg tttcttcgtt ctcataaact
     3241 ttttttgctt cattcactgc tttgatattg aatgtctcat cccacgccca gacagtgact
     3301 ttttcttctt tgtctgctgt actactagca cttccgcatc ctgttaagaa acctgatgct
     3361 gccgctaaac aaacgactcc agcaattaac tttctgatgt tcatttttat ccgctccttt
     3421 tccatccatt agttgtttac gtttgctaca ttcatcatac caaaatttga aaacggtttc
     3481 tttattattc agatacttca aaaatttctc ctaaaataat aaaaaaatac aaatcaacta
     3541 tgacaaaagg aataatctta gcatctagac caaagatcga aatggtgagg tttctttaaa
     3601 ataaaaatat ccttgcattt tctcctagaa ataagtattt ttaaattaca agactattct
     3661 taaggcgggt aaaaaaatgc caatacgcgt aattcttatc gatgatgaac agacgatttt
     3721 agatggaatg aaacagttga tcaattggtc tgagcacggg tttcaattaa tagggacttt
     3781 ttccagtccg ctgaaagcgc ttgatttttc tttggtacat gcaatcgata tcgtggtcac
     3841 agatgtaatg atgcctgaat taaatggaat cgaattatcg cggctattaa aacagcaaca
     3901 acctgaaaca cagatcctta tcctctctag ctatgatgaa tttgatatgg ttaaagattc
     3961 ttttaaagaa ggcgtcgctg attatctttt aaagcctcga ttgagtcctg atttttttct
     4021 aaattcctta actgccgttt cacaaaaaat caaaaaaaag cccaacaaaa gcccaatcac
     4081 caatcgttat gagcagatct gcgagaatct ttcacagcag attgctggac aaactcgtcc
     4141 attgcttgac cctcttcttt ttgaacacac cttgtttttc tgttatatac cgaaaaacgg
     4201 ccattcagtt caaaacaagg ctctaaacaa aaacagtcga tcacccattc attgatggat
     4261 agcgacgatt cgtttactat ttatcctgtt tctacctttt cggaagaatc cggctatgta
     4321 atcaatactg attccaaaga tacacttagg aagtttgttc aaaagtttcg tcaagaagtt
     4381 tttccaggtg atttttttgt tgtttctgat tcttttgcaa tccaagatat caatgaaata
     4441 ttccaagaga tcagaaattg caccaaagga caacgtttct atcataaggg aaagaacctt
     4501 gcttatcagc atgaacttct tccgttatta accaaccacg agcagcaagc aagtagttat
     4561 ttaacaaaaa tcgttcataa agactacgct ttagctgtca aagaacttga gaatttcttc
     4621 acgacgatat tggaacagcc tattgatcca gcttatttga aacatgaggc aatcaatcgt
     4681 ttctatgcat tactcaacgc tttggctgac gagcatgttg ggaatgaaga actttctttg
     4741 ctcaagatcg cccttccttc tttattagcc gatgctgagt atttcgaaga tttttctatt
     4801 cttgtcaaag aaacacttga gaaactcacc cacttttctg caaatgcaaa aaaagacaat
     4861 ttcgatatct tgactttgat ctacgagttc gtccaggaaa attatgagaa agaaatcaat
     4921 ttacaacttt tatccgaaaa atatcatttt tcatatagct atctctcagc catctttact
     4981 gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag tccgtatcag taaagccaag
     5041 ctctttttga cggaaacacg gcttactttg acggaaatct gtgagaaagt cggctatacc
     5101 gaactgggtt atttctccag agtttttaaa gaagagacag gaatgacacc ttctcaatac
     5161 cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga gcatgaactc tttgccaaac
     5221 ttctgttcat tttgttcatc ggtctttttc tgcaagccat cgtcatttct ttgtttattt
     5281 atcatcgatc aagggatgcc tatatccagc tgttcaatca atcgaatgat gtggtactaa
     5341 aaaagattca atctgaattt gaaagtttga atgatacaat cgagaataca ttagccgctt
     5401 ttgattctaa tccagctgtc aaaagctatt tttccaatga tccagcccaa catatggaac
     5461 agcttcagca actaagaaca atccaaaaaa tgaatgactc tctttcaaaa atccatccaa
     5521 tgatcgatta cgatgtattg atctttggag aaaatggaag aacttttgtc ggaaacgaca
     5581 tgctcactgc cgtatctgcc gattcttttt ttcaatctgc gattgctcag agagtgaatg
     5641 aacgtgctgc tgatacacaa atgctttttg cacaccacgg attgactctt cgcgataaga
     5701 aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac attgaatcac gtttacggat
     5761 atgctgtttt atcgatctca tccaagcaac tagcgaatct ttttcaatct gtagtaaatc
     5821 ctgagatatc gaagatctcc ttcatgaacg aagaacagac gatcatcgca tcaaatgaag
     5881 aaaatacaat tgggagccga tcaatgattt tcaaaaaact aacagtaggt gaaacaacga
     5941 tttcaaatgg acagcagttg acccgtcttc ctctgtaccg ccaggattgt acattactca
     6001 gtcaagtcga tcttcattct ttatctaacc aaatgggcgt gatttttccg attattttgt
     6061 ataatatcgt gacacttgct tttgctggct cattggtatt tatgtatttg gatcgacaca
     6121 caaaatcgat ctaccgcttg attgattcgc taaaacggct agaggaagat ggcttaaaag
     6181 ctactgttcc tgtacaagga agccatgaag tccaattgct agggaatacg atcaatcaat
     6241 tgctaagtaa tgctcagcat cattatgaac agacgatcca agacgaaaag aagaaacgtt
     6301 cgcttgaaat ccaaactatg caagcacaga tacagcccca ttttatttat aatacgctga
     6361 ctagcttgaa atttttgatt tggcagaaaa aaacagatga agcagttcaa ggaatcgaca
     6421 gtttcattac tttactaaga agtacgattg ggaaaaaaga agaagtgatt ccagtcaagg
     6481 aagaaatcaa aagcgtacaa agttacatcg atcttttgag tatgcgatat ggcgaaagaa
     6541 tctcggctaa aataatgatt cctgatgaac tgcagtcatt atctatgccg aatatgatcc
     6601 ttcaaccaat tatcgaaaac gcctatcttc atgcttttca caataaaacg caaggattca
     6661 tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt cgaagtgatt gataacggcg
     6721 atggcttcga tactgaaaat accaaacaaa aaaatgatca tttttcagga atcggcatca
     6781 gccatgtaga tgagcggata cgcctaatgt atggcgatgc atatggctta acgatccaat
     6841 cagtgattgg gacaggaacg actgtaacga tttgtctacc gcttcttcct aaaaatcaat
     6901 cagaatatca aaaataaaga atagccaagc gctgattttt ttattttaag ttaaataaat
     6961 caatcagtat tcttgacttt catctacgcg tctcttctac tgtcagcact ggataacagc
     7021 ccaatatttg actttctcct ccgagcatct tgatttcttg gagcgcattc tctactaatg
     7081 tcattggacg gtccaacaac aaatcgatca cgaaaaaata ttctcccaag ctagttttca
     7141 atggtcggga ttcaatctta cttaagttga tttcccgcca gccaaaagct gccagcattt
     7201 tatgaagcat ccctggccga ttagcaggta gtgtcaagat gacactcatt tttactggag
     7261 ctgactgctg gctggtcatc tttcggtcac cgacgatcca aaaacgtgtc tggttcaact
     7321 cattatcttg gatattctca gctaagatct ccaatccaac atgctgtgct gtttctaatg
     7381 aagcaatcgc tgctgcgtct tctttcggat gttctgctac atacattgct gcagcagttg
     7441 ttgattctgt tgctactaaa ggaacattag gataatgcgt ttctaaaaac tgttgtgatt
     7501 gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt tgttgctgga ttgcctaaaa
     7561 gctgctgctt gataggaaga acgatttcac ttttaacttc gacttctgga tgtttggaaa
     7621 gaagatcgat tgtgtgatga acagctcctt ccaatgaatt ctctacagga acgacagcca
     7681 gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg gatggaagca tacgcagtca
     7741 attgttctgt aggaaatagc tgacaagccg cctgataagt gaatgaactt tctggcccta
     7801 gatagctgac gttcatatgc ttttgatcct ttctataatg gtatcgatga tcttttctgg
     7861 tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct tcataccaag aaagtcgttg
     7921 tgccaataat gcttttattt cttctcttgt ttttccaaga gctaaaggtc gaatagacgt
     7981 ttcatcttgt tggatacgat caactagaca gtccgcttct gcctctaagt aaagaacaat
     8041 cggctgtgtt tttaaaaaac gccgattttc tgcactttgg acaatccctc caccagtcgc
     8101 gataattttg tcttcatttg acagctttct taaaatatct gactccactt ttcgaaagct
     8161 tttttcaccg taatagtgaa aatattcggc aatcgacaat tggatatgtt cctcaatctt
     8221 tgtatctaaa tctacatact ctttttgtaa acattgagct aaccctttac cgattgttgt
     8281 ttttccagcg cccatgaaac caatcagcaa aatgctagcc atgagcttct cctcctgaca
     8341 caagttctgc taaatcgtca aaaaatgccg gataagagat tgaaacagct tcagctcctt
     8401 ctagttcgca aggtccatca gctatcaaag cagctacttg cagcatcata ccgattcgat
     8461 gatcgcctct gctggacact tttgcgccat gcagaggtgt cggcccatgg atgatcagac
     8521 cgtctgctgt cgcttttatc tttgctccca ttttctgtaa ttcttctgcc accgcatcaa
     8581 ttctgttggt ttcttttact tttaattctt ctgcgtcttt gatgatcgtg attccttctg
     8641 cttgagtagc cactaaagct agaatgggca attcatcaat cagacgcgga atgatttctc
     8701 caccaatcgt tgctttcttc aaatgactcg tcttgacact taaatcagcc gattggttct
     8761 gttcattgtg attcgtctgg gtaatcgctg cgcccatctc ctccaacaca tctaagatac
     8821 cagttcttgt tggattgacc ccgacatttt ttaacaacag ttggctttcc ggaacaagaa
     8881 gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc tggaacagtt atctgttgac
     8941 cagttaattt ttgcggtccg gtcactatga tcgttttatc ttccactgtg atccttccgc
     9001 caaattgacg aatcatttct tccgtatggt tacgggaacg ttctttttca acgattacgg
     9061 atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga tttgacttgc gcactggcta
     9121 caggcatatt gtatcggata ggtgataaag agcgggttcc tgtcacagtg attggtagat
     9181 actggtcatt ttcttctcct tgcaagtcag cgcccatctc gcgtaaaggt tccatcactc
     9241 gccccattgg acgtttagac aacgaagcat ccccgaacag agtagtcgta aaaggctgtc
     9301 cagccaaaat acccatcaat aaacgtatgg tcgtaccgga gtttcccatg tcaattgatt
     9361 cggttggttg gacaaatgag tggctaccgc gaccatgaat cttgatcacc tcttcctctt
     9421 cttcgatctc gacacctaat tgttggaagg catgtaaagt actcagacaa tcttctgcgc
     9481 gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc tccaaacatg atgctgcgat
     9541 gggaaattga tttatctgct ggtatcctaa cagtccctct taatccatgt atttgttgta
     9601 ataattgcat ttatccagcc tcctatttga tccagcaatg ataactggta ttagacataa
     9661 tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa actgatttgc agtattccta
     9721 aaatatcttc cctggtctct tggatcttca aattaatcaa agaaactccc gcttttccga
     9781 tcagtccagt tacttctgca ataacgccag gttcatctgg cacatcgata aataaatcaa
     9841 aaaaggcagg aatcgcgcct tgcttatgga caggcaactg gtctcgactt tcttttgccc
     9901 gattgaaaaa agaaaagatt tccgattggt tctcagtcat gatccattct gctatttgtg
     9961 tcatttcttg ttgccaatct gccaatcgtt ccaataatat ctgcttattg ctcaacaaaa
    10021 tatctgtcca catgacagga tctgaggaag cgatcctagt gatatctcga aagcctcctg
    10081 ctgccagttg tttggctcgc ggatactctt gattgaattg ttctgcctga ttgactaagc
    10141 cagctgccag aatatgtgga aaatgactta gcattcctgt tatacggtca tgttctcttg
    10201 ctgtaagagt tacatatttt gctttggttc cgcaaaatag ttcttgcagt ttttcaacat
    10261 cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc attttcaaat agtttagcat
    10321 ctgctgcctg tatacctgat ttatgagaac cagccattgg atgtccaccg acaaaccgaa
    10381 gatttttctg ctcagcggat gtcacgactt gctgcttcgt actgctgaca tccgtaatga
    10441 tgacgtgatc agacaagttg attctttcaa ggacatcaag ataagctaag gttgtacgga
    10501 cgggaacggc taataagata acgtctgctt gttctgcacc tgtttcaaaa tcacttgcaa
    10561 cgtaatcaac gatctgctgt tctactgctt gctcacgggt ttttgactga ctatcccaac
    10621 caactactat cagttctgga ttggtctgac gaatacaaag tgccatagaa gcaccaatca
    10681 gtccaagccc cacgataaaa acatgttgtg ccatcttatt tgcccccttt ttagtaatgt
    10741 ttcaagtagt cacggtactc cttcactgca gctttcaact caacaagcga atcacttggg
    10801 aattttgaca atagctctgt cgctaccaca gtggctacaa cattttccgc aacgacgcta
    10861 gctgcaggaa ctgctgtact atccgaacgt tctacacttg ctttgtaagg ttcttttgta
    10921 tcgatatcaa cactttgaag tggcttgtac aatgtaggaa tgggtttcat gaccccgcga
    10981 atgacaagtg gttcgccatt ggtcattccg ccttcgaagc cgcctagatt attggtacgt
    11041 cggaaatagc ctctttcttc ttcccatagg atctcatcca tcacttctga gcctggtaat
    11101 gaaccagaag tgaatccgac cccaaattct acgcctttaa aggcattgat actaaccaca
    11161 gcttgtgcga ttttggcatc tagcttcgtg tcccattgta cgtagcttcc taatccagct
    11221 ggaacgcctc caacgagcac ttctacaatt cctccgatcg tatctccatt tttctttgtc
    11281 tgatcgatca aatcttttat tctttgctca actgctggat caacaactcg tacttctgac
    11341 gcttcagaaa tttctttgat ttcttgaatc gagatatttc caggtatttc tgcttggatt
    11401 ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa gttcttccag aattttcttg
    11461 gcaattgcgc cgattgctac acgcatggtc gtctctcttg cagaggaccg ttcaagcaca
    11521 ttccgaagat ctcgatgatg gtatttcata ccgcctacca aatccgcgtg tcctggacgc
    11581 ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca cttctgctac agacatgaca
    11641 gttgtccaat ttttccaatc tttattttct accactaaag tgacaggtga accaattgtt
    11701 ttgccgtgac ggatgccaga cgtgatccga acacgatctt tttcgatctt catccttcct
    11761 cctctgccgt aaccagcttg tctgcgagcg agttcgtgat tgatttcttc ttctgacaga
    11821 ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt ctggtccatg ggattctccc
    11881 gcagtcatat aacgcatctt acagtcctcc taagtaatct ttgaatgtct ctgtgggaac
    11941 aggaacgatt tttgcttgcc caatcttttc tagcaagatg atattcaatt ggcttcctct
    12001 tgctttctta tcatgggtta tcgcgtggaa taattcatct ggatgactta gatcgtacgt
    12061 aatcggcaga tggaattttt gaagtatcct ttctaaagca gctgtcgatc cagttggaga
    12121 caagccgatt ttttctgcat gagaagtgat ggctaccatt ccaatagcta ctccttctcc
    12181 atgactgact accccatatc ctgctgtatt ttcaattgca tggccaattg tatgaccaaa
    12241 atttaaaata agtcgatttc cttggtcaaa gacatcttct tccactactt ttcgtttgat
    12301 ttccaacgta gcagtaatga ttggaacagc atgttccaga agatcttttt cgtctttcag
    12361 ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct gctgatttga tgatttcagc
    12421 gattccttct cgtaaacgac gtaccggcaa agtttttaga acctcaggat caatcaatac
    12481 accagctggc tggctaaatg ttccgacaag gtttttcgct ttgtttgtat tgactgctgt
    12541 cttcccgcca atactagaat ctacttgtgc aagtagcgta gtcggaattt gaacgaaatg
    12601 gatcccacgc atgaacgtcg aggccacgaa tgctgctaga tcacccacca ttcctccacc
    12661 aagtgcaagt atcccatcgc tgcgggtaaa atcattatct gctaaaaaat cgtataactc
    12721 agctgcttgt tctaaagatt tactggtctc acccgccggt acgattgaaa ggactggttc
    12781 aaaattagct tgtctcaatt ggaacatgat tttttctgca tatagtggag caacgtttgt
    12841 atcagtgatc acagctactt tttgaggtct ccaaatcgtt tgaagccatg atccagcctg
    12901 ttctagtgcg cctttttcaa tatgaatatc gtatttttgg ttatcaacat gtacagtaag
    12961 cattcgtttc acttctttct tttaaaaagc tggaattaat cgagtgtctg aatcttttcc
    13021 attgcttctt tcatgatcgc aacttctttc atcatgcgtg agtaagtctt ttcattcaac
    13081 gattggggac cgtctgacca agcatttgca ggatcaggat ggatctctac gatcatgcca
    13141 tctgctccgc ttgccacacc cgcacgagcc attggtggta caagttccca aattcctgta
    13201 ccatgacttg gatcaacaat cacagggaaa tgagttaatt ttttcatcaa tgggacagca
    13261 cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc gaatcccacg ttcgataaaa
    13321 atgacaggag atttgtcttc gactgcaatg tattctgcag cattaagcca ttcattgatc
    13381 gtaccggaaa ttccacgttt caatccaaca ggtttacctg ttttaccgac agcagatagc
    13441 agtttaaaat tttgcatatt acgtgcgcca atctgtagga tatcgctgta ctcagccacc
    13501 atatcgatat gcccttcatc catcacttca gtaatcactt tcattccaaa ttcatcagcc
    13561 gcttgacgga tgtatttcaa tccttcttct tctaaacctt ggaaagcata tggagaagta
    13621 cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc cggctttggc cattcgcgca
    13681 cattctctga tttggtctaa tccttcgata gaacaaggac cagccatcgt cacgaaactg
    13741 ccgtcaccaa tttttactcc gtctacatcc acgactgtat tgccaggatg gaattctcga
    13801 gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt ctactccttc atagcgtgta
    13861 aatgctcctt cttgtaaact tcgcgtatca ccttttagtc caatcactac tcgttctgtt
    13921 ccttgatcga ttgagacttt gaatccttct ttttcgatat gatcgacgac tttttttatt
    13981 tgttcttccg ttgcttcttt tttcataatt actatcattg tttttcccgc tttcttttgt
    14041 ttacttatct atcttggctg attttctcta ctttttcaag gtggttttac attaattcct
    14101 actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt ctttcctact tatgacccag
    14161 ataatcaaca aaaaaagatg tccctgtagg aaattgcctc tacagtgaac atcttcaacg
    14221 agccttaaaa agcgctgcaa aaatataaaa tagccactat agatgaattt ctctacgtgg
    14281 ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac aaacctggtt tgtttgtacc
    14341 cacgaagtca tgaatacaaa cctatctaaa atagctaaag taatacgtat tcagttttgt
    14401 aagttttcta gatttcataa aaaatcgctc caaactgatg taagaattgt acctagtata
    14461 gacataaaaa aatcgactgt caatcatttt tatgaaactt tttttaattt tctgatagtt
    14521 aactttgttt ttcagaaaaa taacaattgg ttttattgaa gaaaatagtc atgaacaaaa
    14581 gtatctgaga acttttttac tctcttgttc atgacatata gaataaagca gctttgtctt
    14641 gtaaactccg tttttcaaat aataatctaa agattgctac tgaataataa agccgatttc
    14701 atggtcctct tcgctgctga ttcggtaagg tgactcaaca tccgctcccc agctattgat
    14761 acccccgact cctcttactt ttgcaaaaat cgtaagaacc gttcgtcttt ctggcggtag
    14821 ttcttctata tgtgttgcct gttccagttc ttctgctttg aatggtaaag cggaaaaagc
    14881 aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct tcttgatctt tatccgtatt
    14941 atccaacgtt tgatttcttg ttagttctac ccatttcgtt tccatatgca tgccgcattc
    15001 ttggggaaca aggtatgggg aaacggggag tcctgccact ttataaatac cttcgacacc
    15061 accagccatc cgatccggat atgtttcccc tgataggcct tcatactcaa aaaattttgc
    15121 tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat tccggtaatc ctttttgtcc
    15181 ataataatgc atattgacaa gcattttacc ctctccagcg atttggtagg aaattgtcac
    15241 ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg atttcaaccg tttcagcgta
    15301 ttcattactt gaatattgat tatttactgg agcaatcggc aaatcgatct ttttattgtc
    15361 caccagtact tctatttctt tgacttttgg atacaatccg gctcctaacc acataccgga
    15421 tttaaatcca aatccgctac ctctgtcatt atcggtcgtt gctcgccaaa aaactggaag
    15481 tgtttcccgg tatagccatt cttttccgtt tttattgagc gattccagtc cgcctcttgt
    15541 ataagaaaaa atataatgcg tattccccga tttgacacct aatgtacagt cgccgaagac
    15601 gattgcaact ttttccgtat ccatatgact tttatttact gtatttttca taataatatc
    15661 ttacctcctg catggcgggt ttttcttgtc catctgcaaa aacgatccca ttccctgaga
    15721 attcatagtc acttggttta tcgtcaaagt caccgccata gcgcatcact tctctgcctg
    15781 tgattggatc agtcacttgg atcgcctgat ctttaaaatc ccatatatag cctccttggt
    15841 acatttcata acgatcaagc aacgtcatgt aagaatccat tccacctaac gaattcccca
    15901 tgtcatgcat atattcacat aagatgaacg gtttttccgc tttattttca aggtagtcaa
    15961 tgatctcttc tggtggcgca tacatgcagc tttttacatc tgaaatcgaa tcttcgaatg
    16021 ctggatttgg aaaattccct tcataatgga caagtcgatc ggggtctact tttttgaagt
    16081 aatcgttcat ttgtcgaatg ttttcttccg cataagattc atttccaaga gaccaaaaaa
    16141 gaatacttgg atggtttttt aatgtttcga aattcgtttt tgctcgatca agaacagccg
    16201 cctgccactg aggtactgca cctggtacgt tgtaagaagg ctcaaatgcg cccatttttt
    16261 gccatgagcc atgggattcg aggttcgttt ccgccatcac atggattcct gcttggtcgc
    16321 ataaataata ccaagtgatc tggttggggt aatgagatgt ccgtacgccg ttgatctttg
    16381 cattttttat gatagccaaa tctttttcca tatcttctat agtgatggcg cgtccttttt
    16441 tcggatgcca ctcatgtcga tttaccccgt tgataatcat ccgttttcca ttgaagtaga
    16501 tgattttatc tttgatttcg attttacgaa aaccgaagga atagtcaata tactccgtta
    16561 ctcttttttc ttcgtctatc gtctccaatt caagcttata taaattgggc tgaaaatgcc
    16621 cccacagtgc cacattttca aatccatcga tgcgaatcgt catttgctct tttaacggat
    16681 attgctgttg atagatttcc ttcccatcag gatctagtat cgctacattc agctgactgt
    16741 ttttggctac ttgctcaaaa gacaaatcta cttcaagttt gccattttga catttgtcat
    16801 ctaagcgagg tttgatccaa agatcttcta aatggttttg tcctcgagca actaagaaga
    16861 catctctgaa gatcccaaaa aatcggaaaa agtcctgatc ttccaagaat gcagctgtac
    16921 ttcttttgta aacctccaca gctagaatat tttcttcttc caaataaggt gttaaatcaa
    16981 attcagacgg agtgaacgaa tcttcggcat acccgataaa atgaccattc aaccaaataa
    17041 acattgcttg ttctacacca gcaaaatgaa tcgagatttg ttttcccttt agaccttctt
    17101 ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc tttagcagct gaaaagatcc
    17161 cttccgcctc tttctcaggg cttgtcgtga aagggggacg gcgaaataca tgtccctccc
    17221 acggatacat cgtattgatg taatggatct tgtcataatt tgctaattca atatgactag
    17281 gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt tttataaaat gtttttggtc
    17341 gtaccgaagg atttggcgaa taacaaaaac gccatgatcc atttaaagac tgtttaaggg
    17401 aggatgtggt ttctacttct tcccttgttg cataacaaac atgatcgcta tgtgcatttg
    17461 attggttcac tctaaaaact tgtggatcat ctaaccattt tatatttgct ttcatacttt
    17521 tttccttctc tctcataact ttttgaaatg aagcagttct gtttggaaat caccttgaaa
    17581 atcggggaag taaagtccaa ctgtcatcaa ttcggccccc gaaaatatcc gcttcgaggt
    17641 ctgttcctga taaagtgcct catcatctaa ccccatcaga tatacttcat ggaacgctgg
    17701 ttgagctgaa gctagtatcc tccctaaaaa cacaatagct tcatcttgtt taggagacac
    17761 aaacatccat gcggcaatat tttcttcaaa aggactcgcc aaacgataat aatggccata
    17821 ctggatcacc ggacgaatcg tttgatagga tataatttgg tcttttactt gctttttttc
    17881 ttcaggagac agctttgtca aatccagttc ataaccaaaa acagcgctca tagctgtttc
    17941 tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga tttggtacag ctgatacatg
    18001 agctgtgatg gacgaaatcg gataagcaag gcttgttcca tattggattt tcatacgctc
    18061 cactgcatcc gtgttatcac ttgtccatga ctgcggcata taataaataa acccggcatc
    18121 aaaccgtcca cctccaccag aacagccttc ccataagatt tccggataat cagttgtcaa
    18181 atgttcaagt agttcataaa gcccgagcat ataacgatgc gctacttctc cttgtctctg
    18241 tgggtcaagg gtaatcgaat agacatctga aagcgaacgg ttcatatccc atttgatgta
    18301 gtcaagagga atcgtatcta aaatctttct catttgtttc tcaatcgtct gccgaacatc
    18361 taaccttgta aaatccagta catgttgtga tctggaagca gaaggcattc tacctggctc
    18421 ctgcataaga aaatcaggat gtgttcgata cagttcagaa tcaaccgaga tcatttcagg
    18481 ttcaaaccat aaaccaaatt tcaatccttt gctatgagca taatctgcta tttcacgtaa
    18541 tccatttgtc aacttgcctt catactcgaa ccagtctcct aatgaagaat tgtccgcatc
    18601 tctttttcca aaccagccat catctaatac gaacatttcg atgcctagct cctttgcttc
    18661 atcaatgatc gccttgattt tttcactatt gaagtcaaag taagtggctt cccagttatt
    18721 gaccagaatc ggccgttcag caaattgatg acgacctctt gcgattcttt cacgtagcaa
    18781 ctcatggtgg atctgactca ttttgttcaa tccctgactt gagtaagaaa ggatcatttc
    18841 aggtgtttga aaagactggc ctgcattcaa ttcccacgaa aaacgatggc tgttgatccc
    18901 accgacgact ctcaattgat tgatctgatc tttttcaagt tcgaaagaat ggttgccgga
    18961 ataaacaaat tgaagtccga tcgcttctcc agtattttct gtcgtatgat gatgaactaa
    19021 agcaataaag ttattcatat ggtgactgct cgttcctcga cggctttcaa atacttttgt
    19081 tccagataaa acagattgcc gtgaaatctg tctttcattg acatgtgctc ctggcaaagc
    19141 aatgacttca tcaaatcgcc tagtatgggc aaagtctagc tggaaactag ccgctttttc
    19201 tagtttgatt gtttctccgg tttcatttct tatctttaca gatcgtgtga tcactgctct
    19261 atcagtaaat atggtataga acaaatcgaa ataaatcgct gtttctctat ccttaagtga
    19321 aatcaccaac gtttgtgcct ctgacttgtc catcacataa gtttgaggca agccttcgat
    19381 ctctggcttc ccatctgtaa tataatggct gtcatatctc agatccagta agtctgatcc
    19441 attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc atgctgccat gagaagagta
    19501 ttcttgcggt agtgtatctt tcgacagaga ccggtcagga tttaagggaa catttcctga
    19561 aaatccacga tctcttcggg gataattttt attgtctttg tactgcttga ctggtttgcc
    19621 aaaataaata tgcgccaata cattgctttc ttctatcttt atcagataag aaagaaatgt
    19681 atttcgtaaa tggaagactc ggctcttttc atcaaataag atgaaatttt tatctgtttt
    19741 tctatgcgta atatccatca tttcactccc aacaaaacgg aaaccgttta ctttttttta
    19801 taattcctgt atactgttta ctaaacaatt ttgtcaataa aaatttttta tttttttgag
    19861 gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa aggcaaatgt ctctcctgct
    19921 acagtttccc gtgtgttgaa taacgatcag acgatccatg tggctcagac tactcggcaa
    19981 cggatagtag aggcagctgc tgcgttggat tatgacatca gtactcgtaa atatatcaaa
    20041 aagagaatgc cttcgattgg tgtgatctct acgatcggca aagcgagcga agaacaggat
    20101 atctattaca aacatttgcg agtagggatg gaagaagaag ctcgacgtct gcatttaggg
    20161 atgaatcgaa tctataatct atctgataat cctaaacaat gggaagatct agatcagtta
    20221 ggtgcggtga tcgttgttgg gactgttacg aaagaatcga ttaccgcctt gttaaaacaa
    20281 aacatgcaaa tagtcgtcgt ggataaccct gacatccagc aagaggtcga tatggtgtat
    20341 gcagatcttg aacggatgac taaaaccgta ctggaattgt tcttagaaaa tggtcataaa
    20401 agaatagcct atatcggggg atataaagtc gatatggatg aattcggtgg gaagcagatt
    20461 tctataaatg aaaagaggat gcgtgcctat cagcatttta tgatcgatca tcacttagaa
    20521 aaatatatgt cttatcatct aggtggctgg acagaaaaac aaggtgaggt acttgcgact
    20581 aatctattag aaaatgaatc ccctcttcct actgccattc ttgtcgggag cgatccaatg
    20641 gcaattggtg tctatcgggc attgaaacaa aaaaatatcc aaattggaga agagattgtt
    20701 gtagcaagct ttgataatat cgagacaatc gcaaacctct cccctggctt gaccagtgtt
    20761 caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa tggcattgga gcgaattgac
    20821 ggtatacggg acgaaccaat cattttgact tatcctgcac gattgattgt tagggaaagt
    20881 tttatcccaa gaacaaaaag gtattgaaag agaggttgtg aaaagccgct tcgtttcttc
    20941 atactcaaaa cgaaacggct ttttcacaac ctcttactta tacttattca caaaatccaa
    21001 tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa tcaaattggt attcatgggt
    21061 aatctctttt tttgtatctg tataaaacaa ggattgcacg ggtaccttta attctgtcaa
    21121 ccgattttct aatgcttgac cttgctcctg gaatgagtat gcatttccgt cagttatata
    21181 cgttggcgga aattccttag aaacatggtc agccacacta gcttctttca attgctcact
    21241 cgttttccaa tcttttgttc caatcaacga ccacgcaacg gttttgacga aaaacttcat
    21301 aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa tcaacaggtc cgcaataaga
    21361 aatggttcct ttcagactat cttttggaag tagctgtttg attttcattt gtttagcata
    21421 cgcatcattc gtttgtatag ctgcatattg caatgcgatt tgtgaacctg cactatctcc
    21481 accaaaaaat aattgttcca tgtctagcaa tttgtcgtct ttttcttcag ctaataaatc
    21541 tttgatcagt tcattcactt gaagaacttg attagggtat tctgaatcag gcgctaattc
    21601 ataattcatc gcaaccactg cgatgttggc gtctgaaact aattttgtcg caaattcttt
    21661 gacacccgat ttatctccgc cgacgaatcc tccaccatgt acccaaaata gaacaggaac
    21721 aggccccttg ctgttttttg gatagtagat gtcataagta ttctctttat acttggactc
    21781 atacgtcaaa tctgtttttt tcgccacgtt tttttctgct tgatcgaacg tttttttatc
    21841 agtgatttga acagtatttg aaaacatatg gttgatcaag aatgctccag gtctggggga
    21901 aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga atgattccga agaaccatcc
    21961 gataaattta agaattttct ttttcataag gctccctcag tagttagtat taagcattct
    22021 gattatacca tagtgttatt tcctatcaag ctctcctaga tgatttaatg attttcccca
    22081 aacttcttct gcaatgcttt tgacaaaaga aattttttcc attgttcttc aaacaaaaca
    22141 ttttcttctt ctgttgaagc aaatccacat tgaggactta agcacaaacg atccaaaggc
    22201 agatatcgtg tcgcttcgta gatccggtca atcacttgct ggtgctcttc catttcgcca
    22261 tttttcgtta cagtcaaaat ctaagacaac taatttatct tcagagactt tctctaaaag
    22321 aacaaaactc ccagcacgtt cactatcgta ttctaaataa taggcacgga cattttcttg
    22381 agtaaaataa tgggtctgct acgtcgtcat cccccctgat gccgccaaaa tcgaataata
    22441 atttccgcgt caaacatgta tatttagtgt tgaatcattt gagaatatga aaataaaaat
    22501 ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa atctgagaca gaatgacgtt
    22561 cattctgacc cagatttgat tttgcacaac tcaacagtcc ttattggcaa atcgccaaaa
    22621 taatgtagac taactaaaaa gactaagaaa caataacaaa agttaacact tcttagtctt
    22681 tctttagcac gtctatttat taaagatttt agggcctttt ctcatgtttt tacgatcatt
    22741 cttaggtgtt tccatttgtt tggatcggcc tccaccttgt ttctttttga tcaattcttt
    22801 cattttttct ttttggtcca tttttattct cctttaacga atgaagcgac taattcgata
    22861 tgatgggttt gcgggaaaag atctacaggc tgaactttct tcacggcata acctgcttct
    22921 gcaaataact tagcatctct tgcaaaagtt gccggattac atgagatata gacgattcgt
    22981 tctggtgaca tttcgattgc tgattcaata aaatgatgat ctaatccttt tcgtggaggg
    23041 tcaactacga tcacagatgg tttgatccct ttttcttgcc attttttcat aactttttct
    23101 gcttttccga cttcataatg aacattttcg attttattat ttaaagcatt gaactgtgca
    23161 tcttcaattg cttctggaat aacttccatc ccatacacct tatccactct gtctgctaaa
    23221 gacaagccaa tcgtacctat tcctgaataa gcgtcgatca caatgtcttt tttatctaac
    23281 tcggcaaact cgatggctgt ttggtacaga tactctgctt gttgagtatt tacttgataa
    23341 aatgactttg ctgagattcg ataggttttt cctaatagct gatcttcgat atagtctctg
    23401 ccatataaaa ctttttcttt gtctcctaaa atcacatttg ttttttcttc attgatattt
    23461 tggatgaccg aaaccacttc tggcaattct tcatgaatag cttcagcaat ttccttggat
    23521 ttaaagaatt tttctttacg agtaactaaa acgaccatca tttcatggga ataatgacca
    23581 cgacggataa tgatgtgacg aagctgtcct tcattttttt cttcattata tcctcgtact
    23641 tggaaccgtt gcaagatatc tctgactact ttgattgctt gatcgatgac aggatcttgg
    23701 atataaaaat cttcgatagg gactagatca tggctattct ttttgtaaaa accggtggct
    23761 aactgtccat cgatacggcg aacagggatc tgtgctttat tacggtagcc gaatggttct
    23821 gccattccga ccgttggaag tacaggaact tctggcatct tagcaatctt cgccattaca
    23881 tgctctactt gtttttgttt gaagacaagc tgttgttcat acttcaaatg ggctaaaggt
    23941 gcgataccta tgcgaagtaa tgcattgttt tctacaggct gacgatcagg tgattgtgta
    24001 ataaatgttt cgacttttcc atatccaaac ttattgcctg cttttactac tagtatttct
    24061 acttcttctc cagggagtgc attttcgata aataatggat aaccatcgat ttttgctacc
    24121 cccattcctt cataactcaa gtcgacgatt tcgactgtat atcgttcgtt tttctttact
    24181 atttgctgtt ctgtcatatt ttgctccttt aagcctattt ttcaatccta ctgaactcta
    24241 ctataaatca gctaattaca caactaaaac cggcactgac cttactacgt tcagcaccgg
    24301 cttttgatta attcttttga ttaggtgttt cgtctgctat ttttccgtca ccgtcgatat
    24361 cttcatccgt taaacgttcg acttctttta cgaattcttt gctgacaacc tctaattctt
    24421 cttcatctgt acctgtgatt gcttcatcag gaatctgatc ggtattggca aagaactcaa
    24481 tgtgttgatg aagattttgg aaatgcatcg gtgcttcccc gccgtattca ccatctaagt
    24541 tgatcattac tggtcgattg atatcatctt ctgtttcaac gaacaaactg cttgttttgg
    24601 tatagattat tcttggatca tcgacatgtc gaccgccatt cagcatgagt gctgcaatat
    24661 gcaagatctc aaagatattt gctgtcttca caatgattaa agaaaacttc ccatcatcca
    24721 atttggcatc tggcgcgatc tgttcgaatc ctccaacaga gttcgtcagc cctaggaaaa
    24781 acatcgaagc atttccgata tattcccctt catcatactt caagcgcatt ttgattggct
    24841 ttactcgagg gagcatctct gctcctttcg caagataagc aagataacca aaaatactct
    24901 ttagttctga tggaacttca taagtcaatt ctgtcaaata gccacctgca gcgatattga
    24961 tgaagtaact gttatcagaa aggccgatgt ccatttttac ggtttggtgt ttttttatca
    25021 cttctgctgc tgctttaata ttatctctag gaatttttaa tgctcgagca tagtcgttcg
    25081 ttgtaccagc tgggatgatg gccattttag gacggtgttc aagcggagcg attccattaa
    25141 ccacttcgtt gattgtgcca tcgccaccag ctgccactac tagatcaaaa cctagttctg
    25201 cgactctaca tgcttcattc ttggctgaat ctggttctgg tgtagttgca taggcgctgg
    25261 cttcaaatcc tgcttcttct aatgcctgta ggatatccgc caaatttttt ttcaataatt
    25321 cttttcccga ggtggggtta taaattacgc gtgctttttt cattttcagc ctctatcgtt
    25381 tcgctaattc atctttaagt agcttattca cgacaccagg atttgcttgt cctttagttg
    25441 ctttcatgat ttgaccgact aggaagccaa ccgcacgatc ttttccattt ttgaaatcat
    25501 cgacagattg ttggttgtta tccaaaattt cattaatgat tggcagtagt ttgttcggat
    25561 cagataattg cacccaacca tttttttcaa ctacttcttg ggcttctccg ccatttgtga
    25621 tcaattcacg gaagactttt ttggcgattt ttgagctgat cgttccatcg gcgatcaaac
    25681 gaatcattcc tgctaagttc tcaggtgtca attttgtctc agctaattcc agtttctcac
    25741 tgttcaagta agcagaaact tcacccatca accagttaga tgcttgcttg gcatctgcac
    25801 cattttccaa aacagcttca aaaaaatcag acatttcttt tgtaagtgtc aataccattg
    25861 cgtcatactc tggaagtcca aactcacgga tatagcgttc gcgacgagaa gctggcatct
    25921 caggcaaact agcttttact ttttgaatcc attcgtcatc gatcacgaat ttcgggatat
    25981 caggctctgg gaagtaacga taatcactag acccttcttt gacacgcatc aaaactgttt
    26041 tattcgttgt ttcgtcaaaa cggcgtgttt cttgttggat ttctcctcct gaaagaagaa
    26101 cttttgcttg acgtttttct tcaaaagcta aacctttttt cacgaaagat aaagagttca
    26161 agtttttcaa ttctgctttc gtaccgaact cttcttgtcc ataagggcga agagaaatat
    26221 tggcatcaca gcgcatagag ccttcttcca ttttcacatc gctgacttct gtaaattgga
    26281 taattgatcg caatgcttct agataagcgt atgcttcttc tggtgaacgc atatcagctt
    26341 cagaaacgat ttcgatcaaa ggcgtgcctt gtcggttcaa atcaacgtaa gaataaccgc
    26401 caataccatg catgtttttt ccagcatctt cttctaaatg gacacgttcg atccggattt
    26461 ttttcttttt accttctact tcgatttcga tccatccgtc atgaccgatt ggttgatcaa
    26521 attgggaaat ttgatatgct tttggattat ctgggtaaaa gtaatttttc cggtcaaaat
    26581 gagtatcttt agagatttca cagtttaatg ccaaagctgc tttcatcccg aattccagcg
    26641 cagctttatt cattactggc agcacgcctg gataacccca gtcgatcacg tttgtattgc
    26701 tgtttggttc tgcaccaaaa tgagctggcg ctggagagaa aatttttgag ttggttttta
    26761 actcgacgtg gacttctagt ccaatgactg tttcaaaatt cattcgtctt tccctcctaa
    26821 aatagctggt tgttgtttat ggaattctgt tgcttgttca aacgcatatg ccgcttgata
    26881 catcgttttt tcatcaaaat aattaccgat gatctgcaat ccaactggta atccttctga
    26941 taaacctgcc ggtacagaca tacctggaag tccagccaag ttgacaggga tcgttaagat
    27001 gtcactcatg tacattgtga ttggatcgtt aatgttctca ccgattccga atgcaactgt
    27061 tggtgaagat ggcccgatga tcaagtcata atctgcaaag actttttcaa aatctcgttt
    27121 gatcaatgta cggacttgtc ctgctttttt gaagtaagcg tcataataac ccgcgcttaa
    27181 ggagaatgta cctaacatga tacggcgttt tacttcttca ccgaatcctt ctgaacgtga
    27241 gttgacatat acatcatcta atgatttcac attttcagag cgataaccgt agcggatacc
    27301 atcgaatcgt tgcaaattgg aacttgcttc tgatgaggca atgatataat aaacagccac
    27361 accgtatttt gaatgaggca agctgacttc ttccacaaca gcacctaatg aacggaatgt
    27421 ttctgctgct ttcaatacag cttcttttac gccaggggcc acaccttcgc ctaagtattc
    27481 tttaggtaaa gcaatcttca ttcctttgat gtcgcctgtc agtccctctg caaaatcagg
    27541 aactgaaacg cctgaagaag taccgtcttt ttcgtcataa ccgctgatag ctgtcaatgc
    27601 taatgcatta tctttcaccg tacgggtcat tggtccgatt tggtcaagag atgaagcaaa
    27661 ggcaatcaaa ccaaaacgtg agacacggcc ataagtaggt ttcatcccta cgatgccgtt
    27721 aaaagctgct ggttggcgga tacttccccc agtatcacta cctaaagaaa ctggaatttg
    27781 tccagctgca actgctgctg cagaaccacc agaagagcca ccaggtactt ttgttgggtc
    27841 ccaagcattt tttgttttct tgaaataaga agtttctgta cttccaccca tagcaaattc
    27901 atccatgttt agcttaccaa cagggatcat atctgcttga tagattttat ccatgaccgt
    27961 tgcatcataa attggttcaa aattgtaaag gatcttagat gcagcggttg tcaagatatc
    28021 ttttgttacg atattatcct tgataccaat tggaatacca gcaaggacgt tgctttcatc
    28081 aatccctttt tcatctaaag cttttgcctg ttccaatgct ttttcttcgt tcaatgtaat
    28141 gaatgcctcg acctcaggct ctgtttcttt gattcgttca aatgttgttt ttgtcaaatc
    28201 ttgtacagtg atttctttcg atacaagcat atgatgcagt tcttctagag aacgattgtg
    28261 taattctgtc attatgcgcc agcctcccca ttatcgatga ttgcgggtac tttgataaag
    28321 ccgtcttctg tttccggcac atttttcaat aattcatcgc ggttccatcc agcttgcgcc
    28381 cgatcttgtc gcatcacgtt tactgtttca accacattcg acgtaaatgg aacaccttcc
    28441 gtatctactt cttccagcat ttcaaccata tcgatgattt tacctaattg gtcggtaaaa
    28501 cttgcaagtt cttcatctgc gaacgcaagt tttgctaatt tggcaacgtg tttcacttgt
    28561 tcttcactaa tcgccatact accccttctt tctaaacgag ttaaaaactt tgctctctat
    28621 tttaacacaa gagtgccgtg tctgaaattg tttattgaaa tttgtctgaa aaaactcatt
    28681 tttcattctt ctactgagcg acttttagcc aatgcatctg ccatttgatc ttctgtccaa
    28741 acttcgattc ctaattcttg tgctttggtc agcttgctgc cagcatcttc tcctgctacc
    28801 acgatatccg tttttttcga tacgctacca gtcactttcc cgccaagatt ttcgatcgtc
    28861 tcttttgctt cttcacgagt aaatcgtgtt agtttaccag taaggactac tgttttttct
    28921 ttaaaaggag actcgacttc ttgcaattgg gcatttcgaa gccctttgta ttcgaaattg
    28981 acgcctgctt gttttaattc attcatcaat tcatggactt cttcgttact gaaataagtg
    29041 actacactgt cggcaatgat atcaccgatc gtatcaagcg caataatcga ctcatagtca
    29101 cttttactca atgtttctag atcaccgaaa tgttctgcta aaatttttgc tgctttcgct
    29161 ccgacatgtc ggattcctaa cccgaaaatc aaccgctcga ccgaattatc tttgctgttg
    29221 tcgattgctg tcaaaatatt atttgctgat ttttctttta ttttgtccaa cgtcaataac
    29281 tcttcttctg tcaatttgta aagatcagca acatctgcta ctagtttttt atcatacatc
    29341 tgttctagta cgcgcggccc caacccatcg atattcatcg catttcttga aacaaagtgg
    29401 ttcaaacctt ctttcatttg agcagggcat ttaggattga tgcaccgtaa ggctacttct
    29461 tcatccaaat ggacaagttc acttccacaa actggacaat gtgtaggcaa ttggtattct
    29521 tcgctgtctt taggtcgttt atctaacacg acttgcgaaa cttctgggat gatgtctccc
    29581 gctttataaa tcagaactgt atctttcaag cggatatcct tcaacttaat ataatcaccg
    29641 ttatgcaggc tggcacggct tactgtcgtt cctgctactc ggactggtgt catgatagct
    29701 gttggcgtta ctacccctgt tcgaccgact gtccattcga tgttttcgat tagcgtttca
    29761 acttcttctg gcggaaactt gtaagctgct gcccatctcg gtgctttgat agtaaaacca
    29821 agttgatctt gtagcgagaa ttcattcact ttgatgacga ttccatcgat ttcatagggc
    29881 aaatccacac gtttgtcatg atattcttca atgtatgacc acacttcatc aatcgaatga
    29941 catagacgtt tttcccgatt cgtgtggaat ccaatttttt ctagctcttc tagcgcatca
    30001 tactgggttt ttgcttgcat aggaccgaaa tcagctactg tgtataaaaa agtgtccaga
    30061 tttcttttcg ctgtgatttt agaatctaac tgacgcaaag aaccagctgc ggcgttccga
    30121 ggattcgcaa agatatcttt tccctctgct tctctgtctt ggttcaattg gacaaatgac
    30181 cgttttggca tgaaacattc gcctcttact tcgatgttca ttggttcttt taatttgatt
    30241 gggaccgacc ggacagtttt taggttttca gtgatgtttt ctcctacagt tccatccccg
    30301 cgagtcgcac ctctcacgaa atttccatct tcataacgca aagaaacgga aagtccatct
    30361 atttttagtt cacagcaata gtcaactaca cgtcccactg ctttttgtac acgttgatca
    30421 aaagctatca gctcttcttt gctgaaaacg tcgttcaaac tgtaaagcgg aatatcatga
    30481 gtgacttttt caaaaccttc taatactttt ccgcctactc gttgagtggg agaatcagac
    30541 gtgatcaaat caggatattg ttcctcgatt gctactaatt ctgcgtattc tttatcataa
    30601 acatagtctt ccactgttgg tttatcttct acgtagtatt cgcgagacca ttggttcagt
    30661 cttgtacgaa gttcttctgc tcgtttagca gcttcgtcaa tcgtcatttc atgttccatc
    30721 atttaccctc cactactaag ctttttcaat tggcgcaaag gcagccaaaa gacgttttac
    30781 tccttgactt gggaaagcca catctagttc tagatccttc gacgtcccgc ttactcggac
    30841 gactgttcct agaccccatt ttttgtgttt gactttatct ccaggtttcc agctgttatt
    30901 ttcccctcca gtagcacttt tagagggaac aaccgctgtc tctggctgtt tatagctata
    30961 tgctgttttt ttagcgaata caggcgtttt tttaggcgta ggacgcatgc cttcgatttc
    31021 cagtaactcc tgatcgattt cttctacaaa acgagaaggt cggttatatt gcgtccgtcc
    31081 atataatgtt ctggagaaag catttgttaa atacaacgct tcttctgctc gcgtgatccc
    31141 cacatatgcg agacggcgtt cttcctccag ttcgctttct tccatcaatg ctcgagataa
    31201 aggaaaaacc ccctcttcta gaccaatcag gaatacaact ggaaattcta atcctttggc
    31261 tgcatgcaaa gtcatcaatg tcacttggga agcatcttct tctaaattgt caatgtcgga
    31321 aacaagtgcc agatcattta agaagaccgt tagtttttct tctggtgcat cagcgtcttc
    31381 ttcattttgc tgttcgaatt gtttgtcgaa ttcttgtgtg accgttaaaa attcctccaa
    31441 gttttcgatg cgtgcttgtg cttctaatgt attttggatt tttaagtctt ctagatatcc
    31501 gctacgatcc aaaacctctt tcgtcaattc tgtcactgtc aagtatggga tcatctgagt
    31561 gacttcttgg atcatctctc caaatgcacc taattgctgt cctgcttttc caccgatatt
    31621 tgccagatcc acattttgcg ctgcttcaag cagtggccat tcatgaagag aagcaaaact
    31681 gcgtagtttt tcgatagatc ctggtccgat gcctcgtttg ggcgaattaa cgatacgctc
    31741 aaaactgatt gaatcttgag gatttaccag cacattcaaa tacgctaaaa tatctttgat
    31801 ttctttacga tcgtagaact tgtgccctcc aaccatttta taaggaatat ttgctttcaa
    31861 cagagtttct tccattacac gagattgtgc gttcgtccgg tacaagatgg caaagtcgcc
    31921 gtaattccga tgattgcttc gaatctcttc ttgcatccgg tctacgataa aacgggtttc
    31981 gtctcgttca ttatctgcac ggtagtaagt gatcttgttt ccttctttgt tttctgtcca
    32041 caagtttttt ggttttcgat tgctattgtt ttcaatgact tggtttgctg cgctaaggat
    32101 gtttttcgtg gagcgatagt tttgttctag caaaattact gcagcatctg gataatcttt
    32161 ttcaaaatcc aagatgttct gcatatctgc accgcgccag ccgtaaatac tttgatctgc
    32221 atctcccacg acgcacaggt tcctaaatct acctgccaat aaattgacta gcgtatactg
    32281 tgcgtgattt gtatcttggt actcatctac atgaatataa tggaatttgt tttgataata
    32341 cgtgagtgaa tcaggatgtt cttcaaataa tcgaatcgta ttcatgatca ggtcgtcaaa
    32401 gtccatacat tgattatatt gaagctcttt ttggtaagca gcataacatt ttgccgcaat
    32461 ctcttcgtaa taactgcctt gcatttttgc aaaatcctga ggggtctgca ggctgttttt
    32521 tgcttgagag attgttccta atatacttcg aggatcatat tttttcggat caatgttcag
    32581 ttcttttagt atccgtttca tcaaggtcag ctgttcagaa gaatcgatga ttgtaaagtt
    32641 ccggttatac ccgataaaat caacatctct tcttaaaata cgcacacaca tcgagtgaaa
    32701 agtcgatacc cagacatctt cgcctccaga tgcgagaatc gcattgacac gttctttcat
    32761 ttcttttgca gccttattgg taaaagtaat cgctaggatg ttccaaggat tgacttcttt
    32821 ttcctcaatc aaataggcaa tgcggtgtgt cagcactctc gtctttccac ttcctgcacc
    32881 tgccattagc agtaatggtc cgtcagtgtg aagaacagct tctttctgac gggggttcat
    32941 cccgtttaat aattcagctt tggatgacat taacaacatc ctttctttta tcaatcttgt
    33001 taattatagc attttcttgg ctttcattaa actagctagt tcaaaatcat ttgtttcttt
    33061 ttatggattt ttccttgtca attcgttgat ttcgcgctaa attaaaagaa agcgaggcgt
    33121 ttgaatggaa aaaaaaggaa aaatcaagaa attagataag actcagatat attttattct
    33181 aaaaggaata tttgttggac tgctgacagg aatcgtcgtt agcctgtttc gattatctat
    33241 cgaaaagcta agcgatttag ttcgaagtat ctatgaaatg agtcgggaac agccgattta
    33301 cttaattggc ctagctattt gctgcatcct tgcagcattt ttcgtgggtt atctggtcaa
    33361 aaatgaaccg gatatcaagg gaagcgggat tccacaagta gagggacagc ttcgcgggga
    33421 attatcaatg aactggttct ctgttttatg gaaaaagttc attggcggtg tactttcagt
    33481 tggtgcgggc ctttttctag gtagagaagg accttctata cagcttggcg catccattgg
    33541 acaaggagct ggacaattgt ttcggagtcc atcttcagaa gaaaagattt taatttctag
    33601 cggtgcaagt agcggacttg cagcagcatt caatgctcct atcgcaggat tactctttgt
    33661 tttagaagaa atccatcact ccttttctcc acttgtttgg ctgacatcat ttgcttcagc
    33721 aatcactgct aacttcgtct ctctttactt tttcggcttg agacctgttt tatatctagg
    33781 tgaccttcct tctttgccgt tgaaatatta tggttcctta gtgatcttag gagtacttct
    33841 aggcatctta ggttttattt atcagaatgt cttgctggct ttgccaaaat tttacaaccg
    33901 attgccttta ccagcttatt ttcacgggtt cgttcctttc ttgctgattt tgccaattgg
    33961 ttatttatgg cctagtactc taggcggagg caatcaaatc gttttagctt ttggacatgc
    34021 ttccttgcca atcattatga ttatcggttt gtttgttctt cgattcgttt tttccatgat
    34081 ttcttacggt gggggtcttc caggggggat tttccttccg atattgacat tgggggcttt
    34141 aatcggtagc ttttatggaa acattatggt tgatttcggg atggatccaa tctacatcaa
    34201 ggattttgtc gttattgcca tggctggtta tttcacagcg attggaaaag caccgctgac
    34261 agcaattatt ttagtgacag aaatggttgg ctctcttaat catctgatgc ctttaggatt
    34321 ggctgctctt gttgcttata tcgtcaatga ccttctcggc ggtaatccaa tttacgaatc
    34381 attattggaa cgtctacttg gaaatactca gaccgcctca ctaaaaggtg caaggacaac
    34441 ttttgatttt ccagtaacgg cagagagttc tttagacgga ttaatggtac gagacttcaa
    34501 ttggcctaaa aatatgctgc taatctctat acgcagagga aatcaggaaa tcttgactca
    34561 cggtgatacg atcatgaatg taggagatat tttggttatc ttgactgatg aagcaaactt
    34621 gccaagaatc aagcaggaaa tcgaggctaa atcttctatc acaaatttga agcaatcatt
    34681 ttaacgaaca tggaaaaact attttacaac aactattcat ctacactact tgattctata
    34741 tgattctata aaaaaagaag aggctgggaa aa
//
LOCUS       DADVXV010000022        34661 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.022, whole genome shotgun sequence.
ACCESSION   DADVXV010000022 DADVXV010000000
VERSION     DADVXV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.022"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            591..1280
                     /locus_tag="KB969_001009"
     CDS             591..1280
                     /locus_tag="KB969_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6869014.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="KB969_001010"
     CDS             1267..2475
                     /locus_tag="KB969_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6869015.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="KB969_001011"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="KB969_001011"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBB6869016.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="KB969_001012"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="KB969_001012"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBB6869017.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="KB969_001013"
     CDS             complement(6578..7273)
                     /locus_tag="KB969_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBB6869018.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="KB969_001014"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="KB969_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBB6869019.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="KB969_001015"
     CDS             complement(8472..8663)
                     /locus_tag="KB969_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBB6869020.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="KB969_001016"
     CDS             complement(8684..9574)
                     /locus_tag="KB969_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBB6869021.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="KB969_001017"
     CDS             complement(9561..10328)
                     /locus_tag="KB969_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6869022.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="KB969_001018"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="KB969_001018"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBB6869023.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="KB969_001019"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="KB969_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBB6869024.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="KB969_001020"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="KB969_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBB6869025.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="KB969_001021"
     CDS             14899..15282
                     /locus_tag="KB969_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869026.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="KB969_001022"
     CDS             complement(15450..16208)
                     /locus_tag="KB969_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBB6869027.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="KB969_001023"
     CDS             complement(16226..17044)
                     /locus_tag="KB969_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6869028.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="KB969_001024"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="KB969_001024"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBB6869029.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="KB969_001025"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="KB969_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBB6869030.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="KB969_001026"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="KB969_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBB6869031.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="KB969_001027"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="KB969_001027"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBB6869032.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="KB969_001028"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="KB969_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBB6869033.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="KB969_001029"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="KB969_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBB6869034.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="KB969_001030"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="KB969_001030"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBB6869035.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="KB969_001031"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="KB969_001031"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBB6869036.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="KB969_001032"
     CDS             27086..27385
                     /locus_tag="KB969_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBB6869037.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="KB969_001033"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="KB969_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6869038.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="KB969_001034"
     CDS             27973..28209
                     /locus_tag="KB969_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBB6869039.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="KB969_001035"
     CDS             28352..30325
                     /locus_tag="KB969_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBB6869040.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="KB969_001036"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="KB969_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBB6869041.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="KB969_001037"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="KB969_001037"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBB6869042.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="KB969_001038"
     CDS             33204..34496
                     /locus_tag="KB969_001038"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBB6869043.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10564 a         6734 c         6854 g        10509 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa a
//
LOCUS       DADVXV010000023        32537 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.023, whole genome shotgun sequence.
ACCESSION   DADVXV010000023 DADVXV010000000
VERSION     DADVXV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.023"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(41..229)
                     /locus_tag="KB969_001039"
     CDS             complement(41..229)
                     /locus_tag="KB969_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBB6869044.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="KB969_001040"
     CDS             499..861
                     /locus_tag="KB969_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6869045.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="KB969_001041"
     CDS             913..2595
                     /locus_tag="KB969_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBB6869046.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="KB969_001042"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="KB969_001042"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBB6869047.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="KB969_001043"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="KB969_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBB6869048.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="KB969_001044"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="KB969_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6869049.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="KB969_001045"
     CDS             6430..7434
                     /locus_tag="KB969_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869050.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="KB969_001046"
     CDS             7435..8379
                     /locus_tag="KB969_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869051.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="KB969_001047"
     CDS             8379..9341
                     /locus_tag="KB969_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869052.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="KB969_001048"
     CDS             9368..10282
                     /locus_tag="KB969_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869053.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="KB969_001049"
     CDS             10308..12089
                     /locus_tag="KB969_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6869054.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="KB969_001050"
     CDS             12437..13123
                     /locus_tag="KB969_001050"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBB6869055.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="KB969_001051"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="KB969_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBB6869056.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="KB969_001052"
     CDS             16733..17542
                     /locus_tag="KB969_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6869057.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="KB969_001053"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="KB969_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBB6869058.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="KB969_001054"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="KB969_001054"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBB6869059.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="KB969_001055"
     CDS             complement(21094..21546)
                     /locus_tag="KB969_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBB6869060.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="KB969_001056"
     CDS             21696..22646
                     /locus_tag="KB969_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6869061.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="KB969_001057"
     CDS             22639..23598
                     /locus_tag="KB969_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBB6869062.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="KB969_001058"
     CDS             23595..24350
                     /locus_tag="KB969_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6869063.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="KB969_001059"
     CDS             24373..25326
                     /locus_tag="KB969_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6869064.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="KB969_001060"
     CDS             complement(25970..26266)
                     /locus_tag="KB969_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBB6869065.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="KB969_001061"
     CDS             26621..26977
                     /locus_tag="KB969_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6869066.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="KB969_001062"
     CDS             26987..27886
                     /locus_tag="KB969_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBB6869067.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="KB969_001063"
     CDS             28403..29134
                     /locus_tag="KB969_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBB6869068.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="KB969_001064"
     CDS             29279..31306
                     /locus_tag="KB969_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6869069.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="KB969_001065"
     CDS             31414..32511
                     /locus_tag="KB969_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBB6869070.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT        10856 a         5667 c         6997 g         9017 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttt
//
LOCUS       DADVXV010000024        32533 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.024, whole genome shotgun sequence.
ACCESSION   DADVXV010000024 DADVXV010000000
VERSION     DADVXV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.024"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            131..505
                     /locus_tag="KB969_001066"
     CDS             131..505
                     /locus_tag="KB969_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6869071.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="KB969_001067"
     CDS             complement(619..1248)
                     /locus_tag="KB969_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6869072.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="KB969_001068"
     tRNA            complement(1382..1454)
                     /locus_tag="KB969_001068"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="KB969_001069"
     tRNA            1668..1741
                     /locus_tag="KB969_001069"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="KB969_001070"
     CDS             complement(1879..2043)
                     /locus_tag="KB969_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869073.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="KB969_001071"
     CDS             2338..3666
                     /locus_tag="KB969_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBB6869074.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="KB969_001072"
     CDS             3868..4701
                     /locus_tag="KB969_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBB6869075.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="KB969_001073"
     CDS             4717..5454
                     /locus_tag="KB969_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBB6869076.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="KB969_001074"
     CDS             complement(5609..6577)
                     /locus_tag="KB969_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBB6869077.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="KB969_001075"
     CDS             6809..7642
                     /locus_tag="KB969_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBB6869078.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="KB969_001076"
     CDS             7676..8515
                     /locus_tag="KB969_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6869079.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="KB969_001077"
     CDS             8541..9101
                     /locus_tag="KB969_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6869080.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="KB969_001078"
     CDS             9300..11021
                     /locus_tag="KB969_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBB6869081.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="KB969_001079"
     CDS             11186..12328
                     /locus_tag="KB969_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6869082.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="KB969_001080"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="KB969_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBB6869083.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="KB969_001081"
     CDS             14128..14775
                     /locus_tag="KB969_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBB6869084.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKLLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="KB969_001082"
     CDS             15168..17813
                     /locus_tag="KB969_001082"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBB6869085.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="KB969_001083"
     CDS             18123..19436
                     /locus_tag="KB969_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBB6869086.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="KB969_001084"
     CDS             19426..20079
                     /locus_tag="KB969_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6869087.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /gene="radC"
                     /locus_tag="KB969_001085"
     CDS             20134..20826
                     /gene="radC"
                     /locus_tag="KB969_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBB6869088.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="KB969_001086"
     CDS             20976..21176
                     /locus_tag="KB969_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6869089.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21430..23109)
                     /locus_tag="KB969_001087"
     CDS             complement(21430..23109)
                     /locus_tag="KB969_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6869090.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23111..23323)
                     /locus_tag="KB969_001088"
     CDS             complement(23111..23323)
                     /locus_tag="KB969_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBB6869091.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23716..25446
                     /gene="efrA"
                     /locus_tag="KB969_001089"
     CDS             23716..25446
                     /gene="efrA"
                     /locus_tag="KB969_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBB6869092.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25443..27203
                     /gene="efrB"
                     /locus_tag="KB969_001090"
     CDS             25443..27203
                     /gene="efrB"
                     /locus_tag="KB969_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBB6869093.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27298..27495
                     /locus_tag="KB969_001091"
     CDS             27298..27495
                     /locus_tag="KB969_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869094.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27648..28133
                     /locus_tag="KB969_001092"
     CDS             27648..28133
                     /locus_tag="KB969_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBB6869095.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="KB969_001093"
     CDS             complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="KB969_001093"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBB6869096.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29010..29537
                     /locus_tag="KB969_001094"
     CDS             29010..29537
                     /locus_tag="KB969_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869097.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29628..30365
                     /locus_tag="KB969_001095"
     CDS             29628..30365
                     /locus_tag="KB969_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6869098.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30369..31286
                     /gene="miaA"
                     /locus_tag="KB969_001096"
     CDS             30369..31286
                     /gene="miaA"
                     /locus_tag="KB969_001096"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBB6869099.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31288..32517
                     /gene="hflX"
                     /locus_tag="KB969_001097"
     CDS             31288..32517
                     /gene="hflX"
                     /locus_tag="KB969_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBB6869100.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10771 a         5522 c         6874 g         9366 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaagt tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta tttttttgta tgaaaaagta
    21301 aataaattta agaggctatg aaagagccac cttgtatcaa ggaataagaa caaacaaaaa
    21361 tggcttctca tgtttttcat ttgttttctc ttatattcag gacaaggtgc tgatttcata
    21421 acctcttatt tattcttcat ctggtgtcat taccattggc aaaatcattg gatgtctttc
    21481 tgtacgttcg aataagaaag gctgaagcgc gccagtcatc gcttctttca atttatattc
    21541 tgaacagtca ggtccattca aacattctct taaagcgtgg aataagattc gctgagcttc
    21601 attgatcatt tctcctgatt ctcgcatgta gacaaatcca cgagagagaa tatctggacc
    21661 agccaagatt tcttttttct tgatatccac tgtcgcgaca gctaatacaa gaccttcttc
    21721 tgaaagcagg tgacggtcac gtaaaacgac attaccaata tcaccgatcc cgctaccatc
    21781 gatatacaca tctccagcca caaaatgccc agcaggacgc gcagaatcgc tagttaacgc
    21841 taaaacatcg ccattttcca tgatgaagca gttttctgca ggaacaccta catcttgtgc
    21901 tagagaagca tgtactttca acatgcggaa ttctccgtgg acaggaataa aatattttgg
    21961 cttcatcaaa cgaagcatta atttttgttc ttcttgtcca ccgtgaccgg aagtatggat
    22021 gttattgatt tttccgtgaa tcacttctgc accagcttca gacagcaaat tgatcaaatg
    22081 attgacactt gttgtattac caggaatagg tgaacttgaa aagatcactg tatcgtctgg
    22141 ctggatttgg atttgacggt gagtaccatt cgcgatgcgg ctcaacgcgg ccatcgcttc
    22201 tccttgagaa cctgtacata ggatcatcgt ttcattggca ggcaagcgat tgatttcgtg
    22261 tgcatctaca aatgtgccgt ctggaacttt gatatatcct aaacgttgac cgttgacgat
    22321 ggcattttcc atgcttcgtc cgaaaacagc gattttacga ccagttgcca cagcggcatc
    22381 tgctgcttgc tgcaaacgga agatgttaga agcaaagctg gcaaaaatga tacgtccttc
    22441 gatttttgaa aagatcttca aaatagaatg cccaatcgtt ttttctgatt tagtaaatgt
    22501 tggaatctca gcatttgtac tatcagataa aaggcacaag actccttctt ccccgatacg
    22561 agccatttta tgcaagtttg ctggttcgcc aacaggagtg aaatcgaatt tgaagtctcc
    22621 agtcgctacg atatttccag aaggtgtttt caccacgatc cctaatgcat ctgggatact
    22681 atgggtcgtt ctgaaaaagc tgacagaagt ctttctaaaa cggatgatcg tatcttcatt
    22741 gatctcatgg agctctgcat ctcgaagcaa gccatgctca tctaatttgt ttgtgatcaa
    22801 cgctaatgcg agaggaccag catagatagg aatatttgct tgtttcagca agtagggtat
    22861 tccgccgatg tggtcttcgt gcccgtgagt aatcaccaag gcttttactt tgtgtaagtt
    22921 ttgtatgatg tagctgtagt cgggaatgac atagtcaatt ccaagtaaat cgtcttccgg
    22981 gaatttgatc ccggcatcaa tcaaaatgat ttcatcttgg aattgtaccc catacgtatt
    23041 tttcccgatt tcacctaatc caccaatagc aaagacgcct gtctcgttat ttttgatgga
    23101 aagtttcata ttaaaactcc actaatgaga aatcagcatt ttctttttcg tactctagat
    23161 gacttccttc tagaagttga acgaattcaa tattgtatgg ggtattttct tccacacgtt
    23221 ggcgagcgtc tacatcgctt tttgcctcaa tgtaaagaga ttttgtttct tcccgtttag
    23281 ggttgcgtac ttttgtttct tgataataaa ctttatagat cattgttttg tctcctttat
    23341 ctgcgtaaag cagtgattta gctagttgat ttttttagac aacacaaaac gaggggacaa
    23401 gccacctggt ttttcatatg ctttgactag aatactggat tcgagtcaaa gagacaagcc
    23461 tcgtttttgc ttatctgttc ggatattttt tcaaccgtac cttctgtata aaaaatatac
    23521 aacaattaat tgttattcta gcataaaaca gcaaataagt atagaaatca actagattga
    23581 aagaaaaaat caatgtttat catcccgcta taatcataat gactttttta tgagagaagt
    23641 gttctattaa taggctcgtt gtgctatcat ttttagtaat gaaaatgtaa caaaagatta
    23701 aaaggagatg agaaagtgaa actaatgtgg cattatacca tgcgttataa gaaattcttg
    23761 tttttcaatt tcatatgcgt atttggtttt attttgattg aattaggact tcctacgatt
    23821 ttagcacgta tgatcgatgt aggaatccgc aatgatgatt ttgattatgt gaagcaacaa
    23881 gggatattta tgatcgttat tactgtaatc ggtattattt tgaatatctt gttaggttat
    23941 tttggttcga ggattacgac taatatcgta gcagatattc gagatgattt gttcgaaaag
    24001 atccaaagtt attcgcatca ggaatacgaa aatctaggcg tatcttcatt gatcactcgt
    24061 acaacaaacg atgcttatca gatcatgttg ttcctgcaaa atattttacg tatcggtttt
    24121 atggcaccaa tgatgttcat tgtcagtttg tacatggtca tgcgtacaag tgtgacactc
    24181 agtttgtatg tagtaggtgc attaccttta ctattattgg cagtcgtagc gattgctaag
    24241 gtgtctgaac cgttatctaa aaagcaacaa aaaaacttag ataaaatcaa cagtatcttg
    24301 cgggaaaatc tttcaggatt gcgtgtgatt cgtgcattcg tcaatgaaaa gtttgaagaa
    24361 aaacgttttg ctgtagtcaa tgagaattat gcttctagtt caaaaagctt attccgtttg
    24421 atggctgttg cacaaccggg tttttatttc ttatttaata tcgtaatggt attgatcatc
    24481 tggagcgggg cagtgcaaat cgatgcaggc gagcttcgtg taggagattt gattgcgttt
    24541 atcgagtata tattccatgc cttgttctca ttcatgttat ttgctagtgt gttcatgatg
    24601 tatccaagag cagctgtttc agctggacgt atccaagaag ccctagatgc caaaccttcg
    24661 attgtagaag atccaaatgg tatatctgat acaaaaacta aagggtatat cgaatttcaa
    24721 aatgtaacat ttgcttatcc aggccattcg caagagccag tgatacgaaa tgtcagtttt
    24781 acagcctctc caggagagac cgttgctttt attggaagta ccggtagcgg aaaatctacg
    24841 ttgatccaat tgatccctcg cttttatgat gtgagtgaag gaaagatctt gatcgatgga
    24901 gtagacgtga gagattatcg gctaagcaag ttgcgagata agattgggtt tattccgcaa
    24961 aaagcgctgc tatttactgg aacgattgca gataatttgc gatacgggaa agaagatgct
    25021 acgcaagaag aaatggaacg tgcagctgag attgctcaag cttcagaatt catttctcga
    25081 aaaccagatg gatttaatga acatttatca gaaggtggtt ccaatttttc aggtggacaa
    25141 aaacaacgat tggcaatagc cagagccatc atacgccgtc cggaaatcta tatttttgat
    25201 gacagctttt ctgcattaga ttatcaaacg gatgcgaagt tacgtgctcg tctgaaaaaa
    25261 gaaacgacag aatctactgt attgatcgta gcacaacgtg tgggaacgat catgcatgca
    25321 gataagatca tcgtattaaa tgaaggagaa gtcgtcggta tggggacgca tcgggagttg
    25381 ttggaaaaat gcccgattta ttatgatatt gccgcttctc aattatcaaa ggaggaatta
    25441 gcatgaaaaa aaccttttct tccttaaaac gtttagctcg atatatcaga ccgtatcgtg
    25501 agacttttct tttagtgatc ctatttacag ttctgacagt ggctttcaac gtggctttgc
    25561 catatgttac aggacttcct actacagaaa tcagccgtaa tattgccaat ggcgaatcaa
    25621 tcaatttttc ttatatattc aaatgtctca tttggatcac agttgttgga atagggtatt
    25681 gtatttcgca attactttct ggtgttttga tgacaaatgt cgttcaaagt gccatgcatg
    25741 atttgagaag agacatagaa gaaaaaatca atcgtcttcc ggtttcatat ttcgataaaa
    25801 accagcaagg aaatattttg tctcgtgtga cgaatgatgt agatgcagtc agcggtgctt
    25861 tacaacaagc ttttattggt atcgtaaatg cgatattggg aattacgttg gctgcagcaa
    25921 tgatgtttta tatccagccg atgatggcgc tgatctctat gatcatgatt ccaacatcga
    25981 tctggatctc aaaacgagtg atcaatgctt cgcagaaata ttttcaaagc atgcagaatt
    26041 ctcttggtga gctaaacggc tacgtccaag aaaatatgac aggttttagt gtattgaaag
    26101 tatatggacg cgaaaaagaa acattggaag gattcaaaaa agttaatcac agcttgaaat
    26161 actttgggtt tcgtgcagca ttcatttctg gcttgatgat gcctctagtt caattaactg
    26221 cctatgctac ttatattggt atggctgttc taggaagctt ttatgttatt actggggcga
    26281 tcgttgtcgg tcaactacaa gcattcatcc aatatatttg gcaaatcagt cagccaatgg
    26341 ggaacgtgac acaattgtct tcagttttgc aaagtgcatc agcggcaacg aaacgtgtat
    26401 tcgagatttt agatgagcca gaagaaaaag aaaacaaagt agatgcttca ctgccagaaa
    26461 cgattttagg agatgtgaca ttcgatcatg tcgattttgc atatgatccg aagaaaccat
    26521 taatccaaga tttgaatttt gaagtgaaag ctggtcaaac cgtagctgtg gtcggtccga
    26581 ccggtgccgg caagacgaca ttgatcaatc tattgatgcg tttttatgac gtagacaaag
    26641 gagcaataag gattgatgga atcgacacca aatcaatgag tcgcagtgat gtgcgttcgc
    26701 tatttggtat ggtcttgcaa gatgcatggc tttatcaagg aacgattgca gataatatcc
    26761 gcttcggaaa gcttgatgcg acagattatg aagtagttga tgctgcgaaa acagcaaacg
    26821 tagatcattt tatccgaacg atgccagatg gatatgatat ggccatcaat tctgagggag
    26881 acaatgtgtc tttaggacaa aaacagttgc tgacgattgc ccgagcagtg gtctccgatc
    26941 ctaaaatctt gattttagat gaagcaacaa gttcagtaga cacccgttta gaagcgttga
    27001 ttcaaaaagc aatggatcgc gtgatggagg gacggacaag tttcgtcatc gctcaccgtt
    27061 tatcgacaat ccgtgatgca gatctgattc tagtgatgga tcaaggtcag atcattgaaa
    27121 aaggaacgca tgagagttta ttggcacaag gtggatttta tgaaaaactg tataacagcc
    27181 aatttgctga ggaagcagaa taagtcatat aagaataaaa cagtttaaaa cttatttttt
    27241 gttctctatt cttgataatg gtaaagtaaa gttatcaaga aaagtgagga cacggagatg
    27301 gaacagtttt taaatgaaaa aattactgaa gccaaaagag aagttgatcg tttaacgcac
    27361 gtctgtcaga cgaagccttt tgattcagct gatttttttg aaaatgagtt tcaaatcgaa
    27421 cgcttggcag cacaaataga agtgtacgaa ttaattttaa aaaaagtaat agaagaaaat
    27481 atagatgtac aataaaaaca ggtaaaacgt cagttaccag atactgtaaa tagacatctg
    27541 gcctgagcag gttttacctg ttttttttct tatgaaataa atatatgcta tgataccttt
    27601 attcaatagg attagtttct acaaaaaatg aaaggagaaa aataaatatg gaacggttta
    27661 tagcatcaaa tgccacagtg attggtgatg tgacattgtc agaagatgtg acgatctggt
    27721 atcaagctgt tttacgcggg gacagtaatt ggataaaaat aggacaaaga acgaatatcc
    27781 aagatggtac aatcatccat gtcgatcatg atgcacctgt agatattgcg gagaatgtga
    27841 cggtaggaca tcagtgcatg ctacatggct gtacaatcga aaaaggggcg ctgatcggga
    27901 tggggaccac gatattgaat catgcggtta ttggtgagaa tagtttgatt ggtgctggat
    27961 cattagtaac agaaggaaaa gttattcctc ctaatgtctt ggcttttggt cgcccagcta
    28021 aagtgatccg tcctttgaca aaagaagaaa tacaaaaaaa caaagaaaac atccagcatt
    28081 atgtcgagat aggtcggatg catgcgcaag gaaaattcaa ggagcaaaga taggcagtag
    28141 catccataaa ataaaaaagg atggtcagtt tgagttgacc atcctttttt atttggttta
    28201 gataagagag cttaaaaaag cttcctttga aacagattaa tttaatgaag aactgttttc
    28261 catgacttca tcgatcaatc catatgcttt tgcttgttca gctgtcatat agttgtcacg
    28321 atctgtatct ttttcaatca cttcaagcgg ttgtccagtg cgttcagcta aaattttgtt
    28381 taagcgttcg cgtgtttgca aaatatggcg tgccgcaatt tcgatttcag ttgcttgccc
    28441 ttgagcgccg ccaagaggtt gatggatcat gatctcagca tttggtaaag caaatcgttt
    28501 accttttgta ccagctgtca gcaagaagct tcccattgaa gcagccatac ccataacaat
    28561 tgtttggaca tctgctttga caaagttcat tgtgtcgtaa atagccatac ctgctgtaac
    28621 tgaaccacca ggagaattga tataaagata gatatctttt tcagaatctt gagcgtctaa
    28681 gaaaagcaat tgggcgatga tcgaattagc aagatcatct gttacttggc cgcttaacat
    28741 gatgatacgg tctttcaata aacgtgagta gatatcgtaa gctctttcac ctcgtgaaga
    28801 ttgttcaatg actgtaggaa ttaaattcat aatagagttc ctccttgatt tcgtttagaa
    28861 atagtgtacc ataatttagt ttctaatacc taaaatgtag tatacatttt tggtcaaaaa
    28921 aggtcaaata aaaaacttag gcaaattagt cgcataaacc cgctttatgg tatgataagc
    28981 agagaaacaa aacaaggagg aacaacagat tgatagttgg tattactggc cttatcggag
    29041 tgctgacagg tgctgtagtt gtctatatcg gcatgatact gcaaatgcgt cacttggaaa
    29101 ataaagaaca gcgtagacgt gaattggaat tgaaagtcaa agaaatcgag acgctgaatc
    29161 aattaaataa aaagatcaac gagatcttgc aaaaacggac aacgctgatg gaagaatatg
    29221 tcagctttga tgcatttgat gattgttata tcacgattga cgattttgcg tatctccaat
    29281 cattttcagc gcaaaatagt ttttatctgc caaattatat tttagacgag ctatttaaga
    29341 atatctccca tcgaaaagtg attttatctc cagatgaaac aatgaagatt ggtggatatg
    29401 cttataaagg cggacgcgtg attttagaga attttacgga tagtctgact gaaatgatca
    29461 atgaaaaaaa agctcagttg aagactatga cgcgccagcc gattggtttc ttctcgaaag
    29521 atgatgtttg gagctgatat tttgaagcat tgccgttgca catgagagcg tggtaatgct
    29581 ttcttttttt cttaatgata caatagaact gaacggagtg aagaaagatg ttacaaatct
    29641 atgcccatcg cggaagcagc ggcacccacc cagaaaatac gcttcctgca tttgcagaag
    29701 ctgtacgagt aggtgcagat ggtatcgaac tagatgtcca tctaagcaaa gatggttatt
    29761 tgatcgttat gcacgacgaa gaagtggacc ggacgactaa cggtaaaggg ctgattcgag
    29821 aaaaaacatt ggaagaactc aaaaaattga atgcaggggg caaattcagc aaagaatttc
    29881 cagcagctaa agttcctgaa ttgagagaag tgttaggact gctcctccaa aaaaattacc
    29941 gagggatgct aatgattgaa attaaaactg atcagtatga atatcccggt atcgaagaaa
    30001 aattagccga aacattaaaa agtagagatt ggccttttca acatgcatat tgcagctttc
    30061 atttggattc tttggaaaaa atcgcattac tggaaccgga gatacagctg gacttattga
    30121 tgagtacttc tgataaaaag atccaactag cagcagaaac cccttatata gaaggagtac
    30181 atccaaaaaa tacttggttg ttcgaacatc cagtccaggc agctgatttt ccaaaagcaa
    30241 ttcgtgcatg gacgattaac gatgaagaag aaatggccaa atgtcaagaa ctcaaaatag
    30301 atggaataat aactgatttt ccggagaaag ctcttcggtg gaaacaatca acgaaaagta
    30361 ggtaaaatat ggaaaaagta ttagtgatcg tcggtccgac agcagtcggt aaaacagcgc
    30421 taagtgtgga actcgcacaa ctatttggag gagagatcat cagtggtgat tcattgcaaa
    30481 tctataaaaa tctggatatc ggtacagcaa aaatcaaaga agaagagatg aataatgttc
    30541 cgcatcattt gattgatgtg atcgaaccta ctcaacgtta ctcagccgct gattttcagc
    30601 attcaggtcg acaattgatt accgagattg cgaaccgagg gcacctacct atcatagctg
    30661 gtggtacggg tctctatatc caatcccttc tatatgatta tcagttagga gcgacagaag
    30721 aagcgaatcc tgagattaga aaaaagtatg aaacgttagc tgaaacaatt ggttcccaag
    30781 cattatggaa tcagttgaaa gaaaaagacc cggcagctgc tgagaaaatc cactggaaca
    30841 atcaacgcaa agtgataaga gctctggaag ttttagagac gacaggacat agtatcacgg
    30901 cacctaaaga agagccaaag caattgtatg attacctcat gattggatta gatacgaagc
    30961 gtagtattct ttatgaacga atcaatcaaa gagtcgattt gatgctagca gaaggtttag
    31021 tagcagaagc gcgtaaggtg tatgagcttg gagaagtcca ggccagtcaa ggtattggat
    31081 ataaagaatt tttcccttat tttgaaggga aagaaacatt ggaagaagca acagaacaag
    31141 tcaaactaca ttcgagaaga tacgcgaaac gtcagttgac gtggtttcgt aaccgtttgg
    31201 atgcacagtg gtttgatctt ataagtgagc caaatcaaaa aagtcagatt gagcaaacaa
    31261 tcaaaaaatg gctggaggcg gaataaaatg gaagaaaaag tgatcatcgt aggggtagaa
    31321 accgaagcaa accagcgtta cttttcagag tcaatggaag agctagttca gctgacgaat
    31381 accgcatcag gagaagtcgt attcacaatt acacaaaaga gaccacaagt ggatcggcaa
    31441 acgattatcg gtaaagggaa attacaagaa ttagttcaac aagcggatgc gcatgaagcg
    31501 gatttgatca tctttaatca tgagctaact ccgagacaga gccaactgat taccgatgct
    31561 gttggtcttc cggtaattga tcgcgtgcag cttatcttag atatttttgc gatgcgtgct
    31621 cgttcgaaag aagggaagct gcaggttgaa cttgctcagt tagaatacct gctgcctcgt
    31681 ttagtagggc aagggaaaac attatctcgt cttggcggtg ggatcggaac aagagggcca
    31741 ggtgaaacaa agttagaaac agaccgccga catatacgga ataaaatttt tgctgttaag
    31801 aaagaattga aagaagtaga agctcatcga gagcgcaatc gccaaaaaag aaaaaatagc
    31861 gagatttttc agattggact tattggctac acgaatgccg ggaagtcaac tatcttgaat
    31921 ctattgacac aagcggatac ttattcgaaa gatcaattgt ttgcaacgtt agatccattg
    31981 actaagagat ggcgttttgc tgaaggattt gagattactg taacggatac cgtcgggttc
    32041 atccaagacc tgcctacgca actgatcgat gctttccatt ctacattaga agaaagtcaa
    32101 aatatggatc ttttgctaca tgtagtcgat gctagttctc cagatcgtat tttacaggag
    32161 cagactgtct taaaattgat ggatgaactg aatatgaaag aaatgccgat actgactgtt
    32221 tacaataagg cagaccagat cgacccagcg atgttcacgc ctacgctatt cccaaatgta
    32281 ttgatttcta ctcagacgaa agaaggtaag atggcgttga tcgaagcaat caaacgtcag
    32341 ctgatggaac taatgacccc ttatacactt tctgtgccaa gcaacgaagg acagaaatta
    32401 agcgagttga gaagacaaac aatggttttg gacgaagcgt acatggaaga aacaaacgaa
    32461 tatgaagtta aagggtttgc aaaaaccaat tcaaaatggt taagaaaaaa ccaataaaat
    32521 tttatttttt taa
//
LOCUS       DADVXV010000025        32362 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.025, whole genome shotgun sequence.
ACCESSION   DADVXV010000025 DADVXV010000000
VERSION     DADVXV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.025"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(73..1014)
                     /gene="ribF"
                     /locus_tag="KB969_001098"
     CDS             complement(73..1014)
                     /gene="ribF"
                     /locus_tag="KB969_001098"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBB6869101.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(1018..1941)
                     /gene="truB"
                     /locus_tag="KB969_001099"
     CDS             complement(1018..1941)
                     /gene="truB"
                     /locus_tag="KB969_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBB6869102.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(2309..4671)
                     /locus_tag="KB969_001100"
                     /pseudo
     CDS             complement(2309..4671)
                     /locus_tag="KB969_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            5119..5292
                     /locus_tag="KB969_001101"
     CDS             5119..5292
                     /locus_tag="KB969_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6869103.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(5449..5796)
                     /gene="rbfA"
                     /locus_tag="KB969_001102"
     CDS             complement(5449..5796)
                     /gene="rbfA"
                     /locus_tag="KB969_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBB6869104.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(5823..8129)
                     /gene="infB"
                     /locus_tag="KB969_001103"
     CDS             complement(5823..8129)
                     /gene="infB"
                     /locus_tag="KB969_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBB6869105.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(8142..8453)
                     /locus_tag="KB969_001104"
     CDS             complement(8142..8453)
                     /locus_tag="KB969_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBB6869106.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(8450..8743)
                     /locus_tag="KB969_001105"
     CDS             complement(8450..8743)
                     /locus_tag="KB969_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBB6869107.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(8765..9940)
                     /gene="nusA"
                     /locus_tag="KB969_001106"
     CDS             complement(8765..9940)
                     /gene="nusA"
                     /locus_tag="KB969_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBB6869108.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(9963..10436)
                     /gene="rimP"
                     /locus_tag="KB969_001107"
     CDS             complement(9963..10436)
                     /gene="rimP"
                     /locus_tag="KB969_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBB6869109.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(10581..14939)
                     /locus_tag="KB969_001108"
     CDS             complement(10581..14939)
                     /locus_tag="KB969_001108"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBB6869110.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(15151..16860)
                     /locus_tag="KB969_001109"
     CDS             complement(15151..16860)
                     /locus_tag="KB969_001109"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBB6869111.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(16928..18196)
                     /gene="rseP"
                     /locus_tag="KB969_001110"
     CDS             complement(16928..18196)
                     /gene="rseP"
                     /locus_tag="KB969_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBB6869112.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(18357..19157)
                     /locus_tag="KB969_001111"
     CDS             complement(18357..19157)
                     /locus_tag="KB969_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBB6869113.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(19154..19966)
                     /locus_tag="KB969_001112"
     CDS             complement(19154..19966)
                     /locus_tag="KB969_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBB6869114.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(20161..20718)
                     /gene="frr"
                     /locus_tag="KB969_001113"
     CDS             complement(20161..20718)
                     /gene="frr"
                     /locus_tag="KB969_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBB6869115.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(20721..21443)
                     /locus_tag="KB969_001114"
     CDS             complement(20721..21443)
                     /locus_tag="KB969_001114"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBB6869116.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(21579..22460)
                     /locus_tag="KB969_001115"
     CDS             complement(21579..22460)
                     /locus_tag="KB969_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBB6869117.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(22559..23341)
                     /gene="rpsB"
                     /locus_tag="KB969_001116"
     CDS             complement(22559..23341)
                     /gene="rpsB"
                     /locus_tag="KB969_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBB6869118.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            23700..24179
                     /locus_tag="KB969_001117"
     CDS             23700..24179
                     /locus_tag="KB969_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBB6869119.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            24396..25487
                     /gene="phnW"
                     /locus_tag="KB969_001118"
     CDS             24396..25487
                     /gene="phnW"
                     /locus_tag="KB969_001118"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBB6869120.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            25480..25608
                     /locus_tag="KB969_001119"
     CDS             25480..25608
                     /locus_tag="KB969_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6869121.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            25612..26157
                     /locus_tag="KB969_001120"
     CDS             25612..26157
                     /locus_tag="KB969_001120"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBB6869122.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(26611..28302)
                     /locus_tag="KB969_001121"
     CDS             complement(26611..28302)
                     /locus_tag="KB969_001121"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBB6869123.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(28722..29669)
                     /gene="arcC"
                     /locus_tag="KB969_001122"
     CDS             complement(28722..29669)
                     /gene="arcC"
                     /locus_tag="KB969_001122"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBB6869124.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(29784..30803)
                     /gene="argF"
                     /locus_tag="KB969_001123"
     CDS             complement(29784..30803)
                     /gene="argF"
                     /locus_tag="KB969_001123"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBB6869125.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(30894..32123)
                     /gene="arcA"
                     /locus_tag="KB969_001124"
     CDS             complement(30894..32123)
                     /gene="arcA"
                     /locus_tag="KB969_001124"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBB6869126.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         8640 a         6933 c         5731 g        11058 t
ORIGIN      
        1 ctgggcttat ttatcaccca ttttattgta attgctagtt atacataaac aagagatttt
       61 atgcataatg ttttattgct gagaaaaata ttcagctgtt gcttgttcat cctccttgag
      121 ttgttcaatc aattcctcta cactagaaaa tttcacttga tctcttaaaa attgattcca
      181 gcgtaccgcg acatgttcac catagatatc ttgattaaag tccaaaatat acaactctac
      241 agtcagctcc cgtccttcac cgaatgtatc attatgtcca attgaaccca tggctggata
      301 ccatgtttcc ccaattttta tttccgacac ataaacacct tctttaggca aatgaaccgt
      361 gctctttact ttgacatttg ctgtagggaa tcctagtagt ctgcctcgtg catcgccatg
      421 gacaactacc ccttctacct catatgtgca acctaatagt tttgctgctt cttttacttg
      481 tccgctgtct agtaatccac gaatacgggt agagctgatt ttttcacctt gttcttcttc
      541 tttagaaact gtgacgattt tgaatcttcc tttggcatat tcaggaaaat gagcgacatc
      601 tgcaatgtct tttggtccat acgtataatc aaaaccggaa acagcatatt ttgcatgtaa
      661 ccctacgatg tattgatcaa caaattcctg cggtgctaaa tgagcaaaag aagaagtaaa
      721 atcaacttca tataaataat ctatacccaa agcggccatt ttttcttctt tttgcttaag
      781 gctagtcaaa tatttcacgc tgctaggatc gatcttttta aagacaatag atggatgctg
      841 attgaaagtc atcaatgcta atttcaatcc ttctttttgt gcaatttcca tacctgtctt
      901 tatgactttc tggtgtccga tatgcacgcc gtcgaaaaat cccagcacta aaacgacatc
      961 gtcttctgga atttgttctg attggtaagg atgtctgatc ttgatgatat tcattcgtta
     1021 ttcctcattt ctcaatactt tactaggttt taatttgttt ttttctttcg ggtttggctg
     1081 ataaatactg acaacttttc ctttataaaa caaagcaatt tcttctgacg gcatttctgg
     1141 gagcgcaaat acagtataat caagtctcat accgtttttt actttctgcc atacttcatc
     1201 agtaatatct actcgtttga accgttccac tcctttttct attggcagca aacaatcatc
     1261 gattgtccca tttttcacag cttgagctac ttcttctaat gtcagagcat ccttctggga
     1321 cataccggca cttgctgttc gggtcagatc agacatgtgc gcagggtaac caagtttctt
     1381 gcctgtatct acagctaatg tgcggacata ggttcctttc ccgcattcta cttcgaagcg
     1441 ccaagaaatg gttcctgtca cttcgtctct tgtcaattca cttgtccgga taaaacggta
     1501 aatctgagcc tttctaacag gacgctccac tgtttcatta ttgcgggcat attcatataa
     1561 ccgcttaccg ttgactttta ccgctgagta cattggtggt atctgggtga tctcaccaat
     1621 aaatgaagcc atcacttcat ctattttttt ttcagataaa gacatatcta ctggttttgt
     1681 ttctacccgt tctccggatc gatcttccgt cgttgtactg aaacctagag ttatctcgcc
     1741 tacatagatt ttcccagaat ctgtcaaata ttcgataact tttgtggctt ttccaataca
     1801 aatgggcaac acaccgtcta cgtctgggtc aagcgtaccc ccatgtccga tttttttcgt
     1861 atgtaagatt tttcttaatt tgaatacgca atcatgactt gtcattccgc gttctttcca
     1921 taaaggtaat aacccgtcca tgtcttttct ccatttcatt tttgatttaa ctgaattatt
     1981 ataacacatt gcatcaatta ctgacgaatt tgacatcata atgaacggtt tttatttttc
     2041 ggcaataaaa acgtaacaaa attcatgctc acgtaaatag aaatcatgtt atgctttttt
     2101 aaaggaggga atagaatgga agattttttc tttgcaccat ttgattggat ttatgggtgg
     2161 cttacaggta aatagtttgg ttttcacttc ccaaaaacga aaaaaaagac tggccattct
     2221 tccagtcttt tttccgtttt ttttatttat tttttcagtt tcttaatcaa tgtaaaaaat
     2281 tctattttgc gggatcgatt ttatcatttt attggtcaag atttttccat ttccaatcca
     2341 atacttctgg cagatcaata ccattttcac gaatatagtt ttgatgttct tgtaatttct
     2401 gatccatttt tttcgcaaaa tcttctgctt gacttccttt gatttttaaa gctgcgtctt
     2461 ttgccaaatg ataacgatca agttcattta ctacacgcat gtcaaatggt gtcgtgatat
     2521 ctccattttc tttgtagcca tgaatcatta aatgatggtt atgacgatca aagaaaatcg
     2581 tgcggaccaa tgtttcataa ccgtggaaag caaataagat cggtttgtct tttgtaaaat
     2641 attgatcaaa ttcttcatcg ctcaacccac gcggatcttg acttggatga cgtaatttca
     2701 ataaatctac gacattgatg aaccgaattt ttagttttgg gaattcttcc agcagcaaag
     2761 ttacagctgc taatgcttct aagttagatt ccgttcctgc agcagcaatg accaattcag
     2821 gttcctcctc ttttgctgtc gaagcccaat caatgatttt caagccttca ttcactaaga
     2881 cggctgcttc ttctgctgag taaaattgag cacgcggatg tttggaagag atgatcaaat
     2941 tgattttttc tgacgagcgg aatgctttat ccatgactgc gagcaatgta tttgcatccg
     3001 caggcagata ttcacggatg aactccgcct tcttttctgc caaatgtgtc aatattcctg
     3061 gatcttggtg gctatatcca ttgtgatctt gctggaagac tgttgagctt gcaatgagat
     3121 ttagcgaagg ataatcattt cgccaagaaa ggtcatgtga tttccgcatc catttgaagt
     3181 gctgagtcaa catagagtca accactcgca agaatgattc gtaacttgca aaaaaccatg
     3241 ccgtccagtc agaacgtacc cttctaagaa cccttcatct tggtgttccg ataattgact
     3301 gtcgatgacg cgaccagatg gcgaaagcca ttcatcattt tctggttcga ttttttccat
     3361 ccattggcga tttgtcgttt tgaaaacttg attcaatcgg tttgattttg tttcatctgg
     3421 tccaaatata cggaaatttt ctggattttt ctcaatgatc tcgcgaacga atttaccaag
     3481 ttcggtcata tcttctgctt taacggagcc tggtttttca aattgcaaag tatatttttt
     3541 ccaatctggc ataataagcg gtcttggatc gattccacca ttggtgatag gattttttgc
     3601 cattctttgg tcaccagtag gcgcgatttc tctgatttct tctaaaatac gtccttgtgc
     3661 atcaaataat ttttctggtt cataggattt cagccaacgg agtaaagcat ctgcatgatc
     3721 catatgttct tgatctacag gaatcggtac ttggtgtgct cggaaggttc cttcaattgg
     3781 ttccccgtcc cattcttttg gaccggtcca tccttttggt gtgcgtacga tcaatactgg
     3841 ccattttggc atcacgacat ctgttgctgt cttcaggcga gcttcttttt ggatggattt
     3901 aattttctcg attgcttgat ccattttttc agccataaca ggatttaatt tttctgaatc
     3961 atttccttca ataaagaaag gttcccagcc aagtccgtta aagtaatttg ctaattctcc
     4021 atctgattta cgtgccaaga tcgttgggtt ggctattttt gcaccattta aatgaaggat
     4081 cggtaaaaca gctccatcta tcactggatt gataaagaca tttgagaacc agcttccagc
     4141 taaaggaccg gtttctgctt caccatcacc aatcacgaca gcagagatta cttcaggatt
     4201 gtctaataca gctccgactg catgtgaaag agagtatcca agctctccgc cttcatggat
     4261 agaacctggt gtttctggtg ctgcatgaga agcaatgcct ccaggaaatg aaaatcgttt
     4321 gaataatttt tgcattcctg tctcatcttc cgttacttct ggatagatct ctgtgtaact
     4381 tccatctaaa taagcattcg ataccatgac ttgtccgccg tgtcctggcc cttcaatata
     4441 aaacatgttc aaatcatatt tattgatgac tcggttcaaa tggacataaa taaaattttg
     4501 gccaggaatc gttccccaat gaccgattgg atgttttttg acatcttcgg gtttcagtgt
     4561 acgtctcagt aaggggttat ctttaagata aagttgccca acagaaagat aattagcagc
     4621 acgccaccaa gccgtcattt tatcaaagta ttctttacta gaataatcca tacataacac
     4681 tccttttcat tattactctt attctagcgc agatactccc aattgaaacc taataagcac
     4741 ttctgttcat ttgtttggat tttatatcta gccaaatgaa caggtataaa aaaccacgaa
     4801 atttttcctt tcgctgacgt tttttacatt gatccaaaaa acttgtcgtt atcacaatgg
     4861 ctgttccgca gttcatttcg ctcctcatca tgcataattt gctgaatgac gctgggccag
     4921 ttaacacatt gctggaaaac tggggctgga tcgagcaatt cctttcctga ttgatccgtt
     4981 ttatgtaaaa gtctctgtta tctttgtcaa tatgtgaatt ggtatcccag ctactatgct
     5041 aatttctaca gggattatcc aaaatttgga tcgtgaccaa atcgaagcgg cgtaatcgga
     5101 aatatcaata acttcaacgt gatttttctt ttaactgtca acggaccgac aaactcaaac
     5161 ttttatggtg caggttccac tgatcttcta gttacttggc tatacctgac tgtcactaaa
     5221 atagattaca atctagcttc cgttatcggt atcttgatct ttatctatat gcaaaaattt
     5281 atatactact agaaaaaaga aagtcgaatt ttttactttt ctttttctct tttttggtta
     5341 gctgacacgc cgcaagacta aagtcatgga actcttaggt aatacgtctt aatgaaaaca
     5401 aaaaaatccc gcaacccctg atttcacagg atttgcggga gtttttgatt agtctttgtt
     5461 caagtcgcga agcaattcat cgatatggtt gccatagaca actgattcat caagttcaaa
     5521 gaacaattca ggtgtcttat aaatacttag attgtgccct aactctcgac gaatcaatcc
     5581 tgatgcttta ttcaatccat cttgtgctgt tttcttatct gatgctaagt cagataaaat
     5641 gctgtaatag atcgttgctt gctgtaagtc ccccgtaact ttcacatctg tgatcgttac
     5701 gttctccaca cgagggtcac ggaccttttt gcgcaaaata tcattgactt cttttaagat
     5761 ttcttgaccg actcggcggt cacggtagtt agccataatg attggcctcc ttttatcagt
     5821 ttttagtcat ttttgacttc ttccatgata aatccttcaa ttacgtcatc tactttgatg
     5881 tcattgaatt tttcaatcat tgcaccacat tcataaccca ttttgacttc tttcacgtca
     5941 tctttgaatc gtttcagact tgcaagttgg ccttcataga ttacgattcc gtcacggatt
     6001 acacggacac cgctatctct acgaatatat ccttctgtta cataggcacc tgcaatcgta
     6061 ccaactttag aaactttgaa ggtttcacga acgatcattt gaccggtgat tttttcttca
     6121 aattcagggt ctagcatccc tttcatcgca gtttcgattt cttcgatggc tttatagatg
     6181 atacggtgaa gacgaatatc gacttcttca gtatcagctt gcacttttgc ctgcggtgta
     6241 ggacgaacgt tgaaaccgat gataatagcg ttgctggctg ctgctaaggt tacatcactt
     6301 tcattgattg ctccgacagc tgaatggacg atttttacac ggacaccttc cacatcaatc
     6361 ttcttcaatg atgcagccag tgcttctgct gaaccttgta catctgcttt gatgattacg
     6421 ttaacttctt tcaattcgcc ttctttcagg ctttcaaata agttatccaa agtcacacgg
     6481 cttgtggcag cacggttttc taataatgca cgtttcgcgc gttcttcacc cgctgcacgt
     6541 gctgtctttt cgtcttcgaa gactacgaaa cggtcacctg cttgaggtac atcattcaag
     6601 ccagtgattt ctactggcgt tgcaggtcct gcttctttat cgcgacggcc aagatcgttt
     6661 gtcattacac ggacacgtcc gtaagtatta ccgacaacga ttgggtcacc aacatgaagt
     6721 gttccttctt ggacaagtaa ggttgacaca ggacctttac ctttatcaag acgtgcttcg
     6781 atcactgttc cgattgcgcg ttgtgttgga tctgctttta aatcttctac ttctgcgact
     6841 aacaggatca tttccagcaa ttcttcgatg ttttggccga atttcgctga gatctcaaca
     6901 aagatcgttt ctccacccca tgcttcagga attaactcat actcacttaa ttcttgcata
     6961 acatgttgag ggtttgcacc tggtttatca attttattta cagcgacgat gattggaacg
     7021 cctgcagctt tggcatggtt gattgcttca actgtttgtg gcatgacgcc atcatctgca
     7081 gcaacaacta agatcgtgat atctgtgata cttgctccac gtgcacgcat acttgtaaag
     7141 gccgcatgtc ctggtgtatc caagaaagtg attggtttac catcaatatc gatctggtag
     7201 gcaccgatat gctgtgtgat tccgccggct tcgccgcttg ttacacgtga atggcgtaat
     7261 gtatccaata aagttgtttt cccatggtct acgtgtccca taatcgttac gactggcgga
     7321 cgtgagacta atttatctgg atcgacttct tctgcctcga agaatttatc gatatcagca
     7381 atgtcaactt ggactttttc ttgtggttcc atgccatagt ccgtcgctaa cagttcaatc
     7441 gtatctttat ccagtgcttg gttttgattg accatgacac caagcataaa taatttttta
     7501 atgatttctg ctggctcacg atgaattttt ttcgcaatat ctgctacgtt cataccttca
     7561 gtatactcta atacatctgg caattcacgg aatttgcgtg gtggtacagc tggtttagtt
     7621 gattgttgct gtttgccttt tttacctttt ttattataac gattacggtt attattatta
     7681 aatttgccgc gattgttatt gtttggtttg ttgttattgt tagtacggtt ttgattgccg
     7741 ccttggctcg ttccttgacg attttggctg ctggtatttc ccgtattatt ttggtttgtt
     7801 gttggttttt ttccttgatt cacttgaccg ctcccttgac cgcgatcttg ataactgcgg
     7861 ttatttttat ttttttgttg attgttcgtt gtttcttttt tacgttgatc gttcggctgt
     7921 tgattggctg gttttctgct tgcttgttgt gcagcttgtt gtttcgtgct tgggtttttg
     7981 aacgcttgtt gcaatttctt ctcatcattg ctagtaatcg cacccatatg gtttttcaca
     8041 tcgatgccaa gttgttgtgc tttttccacg acgtctttac tagatttttt gagttctttt
     8101 gctaattcat agattctttt gttgcccatg caatcacctt cctaaccttc aattagctcc
     8161 ttggtcttct tcgcaaatcc ggcatccatt attccgaata ccttgcgagg ttttccgatc
     8221 atctgcgtga tttctgcttc agaaaatagc tcaaagcaag gaacttcata atatgaactc
     8281 ttatctttta tcttttttct tgtattctcg cttgcatcgg ttgccacaaa caccaatttt
     8341 gctttttgtt tgcggatttc agcaatggtc agttcttcac ccgtgattag ttttcccgcg
     8401 cgcatcgcta gaccgatgag attcatggct ttttgccgat taactgtatt cattttccaa
     8461 ataactcttt acgtgctttt tggtgagtga catagtcaag aagttcttga taaaactcat
     8521 ctgttaatgt tgtttcgagt actcgatcga gaattttttt atcccaagct tgttgtactt
     8581 cttccggctc aagtgagaca tacgctcctc gtccaggcat ttttccagtt ggatcgatcg
     8641 atacttcccc ttcttttgaa cgggtgattc ggaccatctc ttttttaggt ttcatttcac
     8701 ctgaaaccac ggatttgcgt aaaggaattt tcctttgttt catctctttg cctccttact
     8761 aaagttaagc ttctggtttt tcttcgaccg tttcattgtt gaatgcaatt gtttcatatt
     8821 catcgtctgt taaatctgac tgaacgattg cttcatcatg cagttcttct gtttcttttt
     8881 gttgttcttg attttcataa aattccgtca tgtcagattc tgatttgata tcgattttat
     8941 ggttagtcaa tttagcagct aaacgtgcgt tttgtccgcg tttaccgatt gctagcgata
     9001 attggtagtc tggaacgaca actgtgcagg cctttggatt tgtctcatcg aagatcacat
     9061 ccatgacttg tgcaggattc aatgcatttg caatgaatac agctggatct tcattccatt
     9121 cgacgatatc catgttttcg ccttttaatt cattgacgat tgcttgaact cgttgtccct
     9181 ttggcccgac acatgtaccg actgcatcga tatttggatc atttgagcga actgccactt
     9241 ttgaacgatc gccagcttca cgggcgatgc tgacaatttc aacgattcca tcatagactt
     9301 ctggtacttc ttgctcaaat aagcggcgca ataggtctgg atggctgcgg ctaacaaata
     9361 cttgcggacc tttagacgta ttttctactc gggaaacata aactttgatt cgatcatgtg
     9421 gttgataaaa ttcatttggc atttgatctt gtttagaaag aactgcctca attttaccaa
     9481 gattgacata aatataacgt ttatcctggc gttcgacgat tccttgcatg atgtcttttt
     9541 cataagcact gaattcgtta taaataatcg ttctttctgc ttcacgtaca cgctgtaaaa
     9601 taacttgttt agccgtttgc gcagcgatcc gcccaaaatc ttttggtgtt acttcaaaac
     9661 ggatcgtatc accgatctca tatgctggat tgattaaaag tgcatctttc aatgagactt
     9721 ccaactgtga atccatcact tcttccgtta cttcttttac cgcatagaca tggatctttc
     9781 cttttttctg atcaaattcc acttcgacgt tttgtgcttg gccatagtga cgtttgtatg
     9841 cagaaaccaa tgctgcttct aaagcatcga tcacgatttc ttttgagatc cctttttcag
     9901 cttctaaagc gtctaacgca tttaacattt ctttactcat tttttctgat tcctctccgt
     9961 gattaaaatt ggatagctaa gcgagctttt gcaatatttt ttcggtcaaa agtcaattct
    10021 ttttctcgtg tttttatgcg tattttcaat gtaagctgtt cagcatcaaa tgattgaaga
    10081 aatccttcat attgtttttc gccatctact ggttggtata aggagacatg gacataatca
    10141 ccaagtgcct tttcatagtc gctttctttt ttcaatggcc gctctgctcc cggggaggat
    10201 acctccagga aataagcttg aggaatcgga tctggatctg ctgcatcaag tttttcactc
    10261 agtttctcac tgacaaaggc gcattcttcg atatcgatac cgccttcttt gtcaataaat
    10321 actcgtaaga accagctttt tccttctttt acaaattcga cttcgacaag ttcaaaattt
    10381 tgttcatcta aaatcggtgt caccatttct gtgactgttt caacgacgct actcaaaagt
    10441 ttcgcctcct taaaaaatta agtgcgtaat tccattaaaa agagtgagcg aaaaatccgc
    10501 tcactcacag ttagtatcat tacctataag aactatacca tactctgctt aaaattacaa
    10561 gcagacagga aaacagatgc ttatagcata tcgaataacg ataattgatt ttcatctggt
    10621 agatctttca atacgccatt gtcgttcata tattcgatca atgtttttga aactttaccg
    10681 cgggtggcaa gatcttcttt ggataaaaat ggaccgtctt ttcttgcttc aacgatttgt
    10741 tttgccacgt tggttcccaa acttgggaca gctctaaatg gtgcgatcaa cgtatcacct
    10801 tcaataacaa agttaacggc atccgattta tacaaatcaa tcattccaaa tttgaatcct
    10861 cgttccagca tttcattggc taactccagc actgtcagtt gattcttttc ttttacggaa
    10921 gcatctaatc ctttgtccgt gatttctttc attgcttgtt tcacagcatc ttttcctttg
    10981 cacatggaga ctagatcaaa gtcgtctgca cgtacagaaa agtatgcaca gtaatacaaa
    11041 atagggaaat aaaccttgaa ataagcgaca cgaagagcca tcaatacgta agctgcagca
    11101 tgggctttcg gaaacatata tttgattttt gaacaagaat cgatatacca gtcgggcaca
    11161 ttattttctt tcatcgccga tagataggtt tctcgcaatt catcagggat cttgttccat
    11221 tgtcctttac gaacagtttc catgatttta aatgccatcc cgctatctaa tccagcatgg
    11281 atcaaataaa ccataatatc atcacgacag ccgattactt ccgccagtgt cgcatctcct
    11341 cgtcgaatca attcttccgc atttcctaac catacgtctg taccatgaga tagtccggaa
    11401 atttgcagta gttctgcaaa agttgtagga tgcgtttctt ctagcatccc tcgaacaaaa
    11461 cgagtgccga attctggaat acctaatgtc cctgttttgg aataaatttg ttcctgactt
    11521 actccaagta cttcaggacc ggcaaatatc cgcatcactt ccgggtcatc cgtagggatc
    11581 gtttgtggat cgatccctga taaatcttga agcatccgaa taacagttgg gtcatcatgc
    11641 cctagaatat ctaatttcaa tacattatcg tgaatcgagt gaaaatcaaa atgagtcgtt
    11701 ttccattccg aattttgatc gtctgctgga tattggatcg gcgtaaaatc atagacatcc
    11761 atataatcgg gaataacgat gatcccccct ggatgctggc cggttgtccg tttgactcca
    11821 gtagcgcctt ttgctaatct gtcgacttct gcacttcgaa actgcagatt attgtccctt
    11881 tcgtatcctt ttacatagcc atatgctgtt ttgtcggcga ctgtaccaat cgttccggca
    11941 cggtaaacat agtcttcgcc aaacaatact ttcgtatagt tatgggcttc tgcttgataa
    12001 tcacctgaga agttcaaatc aatatcgggc actttgtctc catggaatcc taaaaatgtc
    12061 tcaaatggaa tatcatgacc gtctttgttt aagcgtgcac cacattttgg acattgtttt
    12121 tctggcatgt caaatccaga accatacgta ccatcttcaa aaaactcgga atattggcac
    12181 tctggacaat aataatgagg ggctaacgga ttaacttcag tgattcctgt catcgtcgca
    12241 acaaagctag agccaacaga gccacgtgaa cctactagat agccatcttc attactttta
    12301 tgcactagtt tttgggcgat cagataaata accgagaagc cattaccatt aatagaattc
    12361 aactcttttt ttaatcgttt ttgaatgatc tcaggtaacg gatctccgta catttgtttt
    12421 gcttttgtgt aactcaattc tgatatttca tcttctgaac ctggaatctt cggtgtataa
    12481 agttcatctt tgactggaat cacttcttcg cagatatctg cgattttatt cgtattttct
    12541 actacgatct ctttcgctgt ttcttcccct aaaaagtgaa atgcagttag catctcatcg
    12601 gttgttcgga aatggacatc cggcaaacta tgacgattca acggattcgc tccgcccata
    12661 gaattgatca aaatttttcg gtaaatggca tcttcttcgt tcagataatg tacattacct
    12721 gttgcaacaa cgattttatc caaacttttt ccgatttcta ccaaattttg gataatttct
    12781 tccaaatcat gttcattttt taccaattct tgctcgatca aaggcgcata gaccgctttt
    12841 ggcataactt caatataatc gtagaatttt gctcggtttc ttgcctcttc tacccctttt
    12901 tgcatcatgg cttcgaatat ttctccctta tcacaagctg agccgatcaa tagattttca
    12961 cgcatctttt tcaattggga gcgtggtatt cgtgggacgc gttcgaagta ttcgacattc
    13021 gacattgaaa tcagtttgaa caaatctttc agtcctgcct gattttttgc taaaatcgtt
    13081 acatggaaag gtcgagccct tttgtaagaa tctccttctc cgatatgctc atttagctga
    13141 tcatgataaa gcatgttatg attgtccatt gcctctttca caaagatcca tgctaagtga
    13201 ccagttgctt cagcatcata gattgctcgg tgatgctgtt ccaagctgac accaaatttt
    13261 ttagataaca cacctaatcc gaaacgtttg aattgaggat acagatatct agctaattcc
    13321 aacgtatcaa tgactggatt ggccgcttca ggaataccat accttgcgta gctagtattc
    13381 aagaacccca tatcaaaagc cgcgttgtgg gctaccaaaa ttgtatcttt tgaaaattca
    13441 aggaacatcc gcaatacttc ttcttccgac tttgatcctc gaaccattcc atccgtgata
    13501 ccagtcagat ctaccgttgt tcgtgacaaa ggatgtcctg gatcgataaa ttcatcaaag
    13561 ctttcgatca catttccttt atacattttg actgcggcta gctcgatgat cgtgtcatat
    13621 actgcagaca atcctgtcgt ttccacgtca aatacgacat atgtggcttc actcaatgct
    13681 tcatgtgcat cattataagc aattgggaca ccatcatcta cgacattcgc ttccacgccg
    13741 tataagattt tcacacctgc tttttttcca gcactatgtg cttccggaaa ggcttgcgca
    13801 ccaccgtggt ctgtaatggc gatagctcgg tgtccccatt tccctgcttg tgccacaaga
    13861 tcagagatgc tgtttgttgc atccatcgta ctcatattgc tatgaacatg aagctctact
    13921 cgtttttccc cttcaggagc ataatctttg cgaggtgtat gtttgacttc tatgatatct
    13981 tgcgcattca tgaccaaatc acggacaaac gtatcttctt gaatacttcc tcgtaccttt
    14041 aaccagctac cgacactgat cgcatcaaat acttgttcat ctttttcgcc gttcgagaat
    14101 tttttgacga taaatgatga agtataatct gtgattttca aagtcaagat cttgcgtttt
    14161 gaacgtagtt ctctgacttc tttgtcgaat acgtacccct caagtgtgac tcttcgttct
    14221 tcttcaacga tactgatcat tggtgtcgtt ggttcatcgg ctggaatatt tcgtcctagc
    14281 tggatgtgga tgggtccttc aagagctggc gattgctctt ttctttcctt tttcttttgt
    14341 tcgtggacaa ctagactttc agctgcttgc ttcataaagg cttctgcctg ttcttgtttg
    14401 cgttcttcaa aaagtttcaa tactcgttcc gcttgctgct catccacttc tggttcgata
    14461 cgaaattttg ggaatccgta actgacgaac aactcttcta ctaatggcaa gtattgttgc
    14521 ttcaaataag aaatagctcc tgtactgtcg attggcaaga tgactttacg atcttttatc
    14581 acaggtacct gcgttttcaa tacttgctgt gctagtggtg tatcgcattg ctgattttcc
    14641 aaagcttggg cccagtaatc ttgcaagagc tgttcatcga atgtctggtc atctgctaag
    14701 atattcagtt tgacttgtgc aatatcttta aaagcgatag tcagatgctg agtcaatgac
    14761 cgatatagca taataggcaa aattttggaa aaatgcagcg taaattccca taaacgcgat
    14821 ttacgatgga ccactacact atccatttca ccagcagtaa gcagtggatg atttttttct
    14881 gcttcctcta gttggatttg ttccaacagt ttttcaaata aatctcgttt ttctgacaaa
    14941 gatatacgcc ctttctgatg agaaacaatg caattgatcg catcttatcc tcttcttttt
    15001 cagtaccttt tagtatactc gttttttctg agttttacat taaaaaattg gaactgcgat
    15061 tcaaatcgca gttccaattt taaaagcgaa tcatcagatt gtcaaaaaca gctgattcag
    15121 ctatttttat tttctgtgtt ttaacgctta ttattcgcct tggttcaaga ggattggtaa
    15181 agtattcacc aattcttctt tacgtacttc aaccatttcg ccagttttct tgattttcac
    15241 ttctacgatt ccatccactg cttttttacc gacagtgatt ctgattggac agccaatcaa
    15301 atcagaatcc gcgaatttca ctcctgcgcg ttcatttctg tcatcaacca gtacttcata
    15361 gccagctttt gtcatcgctt cttctagttc attcgtcagg tttgtttggt attcgtcttt
    15421 tagattcatt tggacgatat gcaaatcaaa tggcgcaatt ccttttggcc agttgattcc
    15481 ttgttcatct gaatgttgtt ctacgattgc tgataataaa cgacttacac cgataccata
    15541 acagcccata atcacaaatt tttctcgtcc attttcgtct agtacagttg ctcccataga
    15601 ttcactgtaa cgagtgccga ttttgaagat atgtccgatt tcgattcctc gagtaaaggc
    15661 aagaacacca ttgttgtctg gtgaaggatc tccttcttgt acaaaacgaa gatcttcata
    15721 agaaagtaca gtgaaatcgc gttctggatt cacattttta tagtggaatc ctgtttcgtt
    15781 cgctccagta atggcattcg ctaaatcttg gacataacgg tctgcatata cttttacgtc
    15841 atctgaaaca ccgactggtc cgacagaacc aaactcagca cctagatatt tttgtgcttc
    15901 ttcttctgtt gcttcttcta aaaagtcagc agataaaaag tttttcagtt ttacgtcatt
    15961 gacttcatgg tctccgcgta ccaaaacaag gacaggttgt tcatccgcaa tgaacaatac
    16021 agacttgatg attttttgag gttcaacaga aaagaaatct gctacttcgt caattgattt
    16081 tacgttaggt gtagctactt tctccaattc aagctgtgtt tcatgcgatt tttttgatac
    16141 atagtagctt gtagccatct ccaagtttgc agcataatca ctttcagtcg aataacagat
    16201 cgtatcctcc ccgatttctg agatcgccat gaattctttt gagtctttcc cgcccattgc
    16261 gccaccgtct ccgataatcg agcgaaattc taagccacaa cgcttgaata cttcggtgta
    16321 ggctttttcg taatctttat atgtctcgtc caaactttct tccgttgcat ggaaagaata
    16381 cgcatctttc atgataaact ctcttccgcg aagcaaaccg aagcgaggtc gtttttcgtc
    16441 acgatattta ggttggattt gataaagatt taaaggtaat ttcttatatg aattgatttc
    16501 attacgcatc aaatcagtaa aagtttcttc gtgagttggt ccaaggatca tttttcgatc
    16561 attgcggtct ttgaaacgat acaagtttgg tccatatgtt tcgtaacgcc cggattcttc
    16621 ccaaagttct gctggcaaga tggcaggcat cagcatttct accgctccga ttttttcaaa
    16681 ttcttcccgc ataatgcgtt tcagtttttc caatacacga tttgctaatg gcagatatga
    16741 ataaataccc gctgatactt ggcggatata tccagctctt agcaagattt gatggcttaa
    16801 tacttctgca tcatttggaa cttcgcgtaa tgttggaatc aacatttttg attgtctcat
    16861 tctatatact cctttatttc ctcaaaatag ttatcgtttg ttattatacc ctatttgtca
    16921 actttttcta gaaaaagaat cgttgaatat cgttccatgt aactagcacc atcaacaaca
    16981 ttaaaaatcc aaagccagct aatgtcaata ttccttcttt ttcttgactt aatggtttcc
    17041 cgcgaatccc ttcaaaaata ttcaagacta atttcccgcc atctaaggca ggaatcggaa
    17101 gcagattgac gattccgaga ttcattgaaa gaagcgccat caaactaata acagttgtta
    17161 caccttgatt tgctgcttct gaagacaatt ggtacatcat gacaggtccg cctaatttat
    17221 ctaaactgaa acctgtaaat agtgatccta aggctttgaa aatttccaat gaaccgctga
    17281 aagcttgacg cgtccctcca atgatcttat ccataaaacc tgtattcatt ggggctttta
    17341 taccaagttg gccaactttt tcgccatttg actctacaga tttcggtgtc acgtcgacag
    17401 attgcacctg accttctcgt tcgatcttaa agtctaatgt tttatccgga tttttcgtaa
    17461 tgactgttgt cagatcattc catgaatgga tttcttttcc gtccacactg actacctcat
    17521 cattttcttt taagcctgct tctgccgcag ctccattagg catgatctct cctacgcgat
    17581 tagtgttcgt cacttgaaca ccaccttgca taaatgccag aatgatgaat aacaggattg
    17641 ccaaaataaa gttattcatg ggtccagcaa agttggtcag catacgctgc cacaatttag
    17701 ccgattggaa ctgtacgtct tttggcgcaa ttctgatttc tgttccgtcg ttttcaataa
    17761 tcgtcgcatc gtgatcaaca gggtaggtta ctacttctgt ttcgtctcca ttcacataac
    17821 cagtgatagt cagctcatct tctaaatcat aacggctcaa ttccatcggg atagcatttg
    17881 tcaattggat tttcttactt aaatttatct tctctacgat gccgtcagaa tttagtaaaa
    17941 gagaaagagg cattcctggt gccatttctg tttcatcatc cccattgcct gccattcgaa
    18001 cataaccgcc aataggtaat aggcgaagcg tatatgttgt cccgtctttt gcttgatgcc
    18061 cataaatttt cggacccata ccgatagcaa attcgcgaac gaggattcct gatcgtttcg
    18121 caaagaagaa atgaccaaac tcatgaacaa tcactaatat accaaaaacg atgataaatg
    18181 tcagaatcgt tttcatagct tttttctcct ttacttgttt tttgtgtttt ttataaaaca
    18241 acgataaaac actataattt taccatagta taccaaagac accaatagta tcaatataat
    18301 gaaaaataaa aacctgcgtc ttttatgaaa ttcacaaaga aacgcaggta tacttactaa
    18361 ataatgccaa ataaatgcat gataggaaat acaaacagca aactgtcgaa acggtctaag
    18421 attccaccat ggcctggtaa gatatttccc gagtctttca catcataatg acgtttgatt
    18481 gcagattcga ccaaatcacc aaattgtccg actgctgaaa aaataatcgt catcagaagc
    18541 atgacaaaca taccatgatt aaatagttct tttgctgggt atagcaataa ataaagaaat
    18601 gcgactacaa cagcactacc aataccaccg agcgcacctt caatcgtttt gttgggcgaa
    18661 atatcaggac ttaacttatg ctgaccataa cgtcgaccaa ccatatatgc tccgatatca
    18721 gttgcccaaa caataaatag accaaatatc aaaacagcca agctttctgt tcgtgcattg
    18781 acaaaattct ggaaacctat tcccacatac aagctgacaa gcacaggaaa acctgcttca
    18841 tcaatcgtat acgtattttt agaaataact gatgttccta aaagaatcat aactataaga
    18901 taaaataaca taaatgtact tacattctct ggaagaaaga aaaaccatct ttcttttggc
    18961 aaaacaagta acactgcacc aacggcggat aaaactcctt caaaacttaa gagtgtcaat
    19021 cctttcatcc gaaacagctc gtaaactcct attactgcta agattgctgc tgtaagctca
    19081 accgctatgc ctccgatcca tataatcgga ataaacaaga ctagcgccac ggctgctgtg
    19141 accacacgtt gtttcatgac tgatcccctt tctcatcttc tgtttttttt acaccgccga
    19201 atcgacggtc tcgattttga taagaggcga ttgcttcttc aagatgcgca ccatcaaaat
    19261 caggccaaag cgcttttgta aaatacagct cactatatgc gatctgccat aacagaaaat
    19321 tactaattcg ctcttctcca cttgtacgga tcatcagctc aggatcttgt aactctttag
    19381 gcaagaaacc tgtcattaaa tgcttagcaa tcaattcatc atcgatttct tctgcgtgta
    19441 tttctccttt tgctacttct tcggcaattt cttggacagc agtcacgatc tctgctctgc
    19501 ttccataatt caaagcaaaa ttcaatacca ttccagtatt gttttttgtt tgctcaattg
    19561 cacgtcttac agcatcttgc gtatgttctg gcaatacgtt ttcataaccc atgacatgaa
    19621 ctttgacatt ttctttaatc aattctggta cgaacgtatc aaagaagtcg acaggtagtt
    19681 gcatgagaaa acttacttca tcttttggtc gcttccagtt ttcagtcgaa aaggcataaa
    19741 gcgtcaacac tttcactcca agccttgatg ctttttttgt gactttcttt actgtttcca
    19801 tgccttcttt atggccagca actcgtggca aacgacggtt ttgcgcccaa cgaccattgc
    19861 cgtccatgat gatggcaatg tgctgaggaa ttggtccatc ggtattaaat tgaaattcgc
    19921 ttttttcttg aatatatttg tttttttgcg gaaaaaaacg taacattctt tttcctccta
    19981 tacttaaaag attcccacta tcttaagtat tatagcaata tctaactgtt tttcctatga
    20041 aatcattgtt tttttattta aaaactgaat aattttttct ttttttaatt tttaaataaa
    20101 agaaatataa ataaaaacag aggaagcgga atgatccgcc cctctgtttt tatgatttta
    20161 ttaaacttcc aataattctt tttctttatc agcagcgatc ttatctactt ctttgatgct
    20221 gttatctgtc aatgtttgta cgtctttttc taatccgcgc aaatcatctt cggtaatatc
    20281 accatttttt tgttgttttt tatattcatc gatcgcatca cgacggatgt tacgaatcgc
    20341 gatttttgca ttttctgctt cttttttaac atctttagct aattcttttc tgcgttcttc
    20401 tgtcagttgc gggataacta agcgaatgac atttccatca ttggttggac tgattccgat
    20461 atcacttgcc ataatagctt tttcaacatc ttgaagaatg ctcttgtcaa aaggtgtgat
    20521 cattaaaaca cgtgcttctg gaatttggat tgatgccatt tggttcaatg gtgttggcgc
    20581 accgtagtag ttcacagtaa tacggtccaa aaggctagcg ttcgcacggc ctgcgcggat
    20641 ttgcccaagt tcacgttgaa gattttgtgc tgcttttttc attttttctt ttgcttctgt
    20701 cataattgca tctgccattt ttatttcccc cttacagttg ttccgatatt ttcgcctaag
    20761 attgcacggc gaatatttcc gtgttcattt aaattgaaga caagcagtgg aatatcatta
    20821 tccatgctta gtgaacttgc agttgaatcc atgacttgta atcctttggc aataacttcc
    20881 agatgagtca gttcttcaaa ttttactgca tttgcatcta ctttcggatc agcagaataa
    20941 acaccgtcta cattgttttt agccatcagg ataacatctg cgccgatttc tgccgcgcgt
    21001 aatgctgctg ttgtgtctgt cgagaagtac gggttgccgg taccgcctgc aaagataacg
    21061 atccgtcctt tttctaaatg acgttctgct ttacggcgaa tatatggctc tgcgatttga
    21121 cgcatttcaa tcgaagtttg cacgcgtgtc ggtacaccca cgttttccaa cgtatcctgt
    21181 aaagctaagg cattcataac tgtagctaac atacccatgt aatcagcttg agcacgttcc
    21241 atgcccattt gtgctccgat ttgtccgcgc cagatatttc cgccgcccac aacgattgcc
    21301 atttcaacgc ccagctcgtg aacttctttg atttcttgga tgatttcttt gattactggt
    21361 ggtttgattc caaatcctgc gtccccagct aaagcttctc cactcaattt taagactaca
    21421 cgctgatatt tcggtgtgac catgttcatt cctccaatat tttctattgc cattttacca
    21481 tacttagatg atttcgacac tctaagactg gtttttcttg ttttgcttaa aaaaagggag
    21541 cgcacaaacc gtgcgttccc gtctgttatt caacagaatt attttttcac ttggctcata
    21601 acttcttcta caaagttatc ttcgcgtttt tcgatacctt cgccaacttc gaaacgtacg
    21661 aatgttttaa cagttgcgcc ttttgatgca acgtattttt caacagtcat atcaggatct
    21721 ttaacgaatg gttggtccac caaagcgatt tctgctttga atttcttcaa gcgtccttct
    21781 accatttttt caacgatatt cgctggtttg ccttcgttca atgcttgttc tgtaagaaca
    21841 gttttttcat gttctaattc agcttctgga atttgtgatt cgtttacata acgaggattg
    21901 atagctgcta cgtgcatagc tacgtctctt gcaactgttt cgtcagttgt tccatctaga
    21961 acagtcaata cggcaatacg tccgcccata tgcaagtatc caccaaatgc agcattgtcg
    22021 tctttttcta caacttcaaa gcgacggaag ctgatttttt ctccgataac ttgagttgct
    22081 tcgatcaagt cagattcaat tgtaccttta tctgttttga ttttcattgc agcttccatg
    22141 tctgctggtt tgttttcagc aacaagttct gcaatttctt ttactaaatc ttggaacatt
    22201 tcgtttttag aaacaaagtc tgtttctgag tttacttcaa cgattgctgc agtgttacct
    22261 ttcacagcaa ctgaagccaa tccttcagct gcaatgcggt catttttctt cgcagccttt
    22321 gccattcctt tttcacgtaa aagatcaact gctttttcca tgtcgccttc tacttcaact
    22381 aatgcttttt tcgcatccat cattcctacg ccagtcattt cgcgtagttc ttttaccatt
    22441 ttagctgtaa cgtctgccat gtttaactcc tcctgtgtgt ttttcttttt aaaaaaagct
    22501 gcttcaaagg agagtgaggc ttgtcgccca gcctttgaaa cagctccatc attcaaaatt
    22561 attctgctga agaattgtcg ccttcaacaa catctacgat ttcttcgatt gatgttgctg
    22621 tgttttcttc tgtgaaatct tcttcaacta cttgatcttc accttggttt ccttcgatga
    22681 aagcatcagc catttttgaa gtaatcaatt taacggcacg aattgcatcg tcgtttgaag
    22741 ggattactac gtcgatttca tctggatcgc agtttgtatc aaccatagct acgattggga
    22801 tatttaattt gtgtgcttct tgaacagcaa tacgttcttt acgtgggtca acgatgtaca
    22861 ttacatctgg gattcttggc atatcagcga taccgcctaa gaatttttca agacgttcac
    22921 gttctttgtt caaaccagca acttcttttt taggtagaac ttcaaaagtt ccatcttctt
    22981 ccattgcatt gatttgtttc aaacggctga tacgtttttg gatagtatcc cagtttgtca
    23041 atgttccgcc taaccaacga tggttaacga agtattgtcc tgcacgagtt gcttcttctt
    23101 tgattgcttc ttgtgcttgt ttttttgtac ctacgaataa tgctacgccg ccttcttcag
    23161 caacgctctt catgtaatca taagctgcat ctactaattt aactgttttt tgcaagtcaa
    23221 tgatgtagat tccgtttctt tctgtgaaga tatatttctt catttttgga ttccagcgac
    23281 gagtttggtg accaaagtgt acgccggctt ctagtaattg tttcatagaa attactgcca
    23341 tgtttgtttc ctccgatttg gttttatttt tcctcttctt atcttctacc ttgccggcaa
    23401 actttttcaa gcacctaccg acaatccaat aagaatgtgg atttgctgat gcataaagca
    23461 ccctcagcta ttatacagac aaaagatccg tatcgcaaga gcaaatatac ttttctgctc
    23521 aacattcaat agtttacctg aaagataaaa agaattcaag aaaaacagta gatttctctt
    23581 tgtttcttta ttatcctttt tccataaaat aattttaggt ataaaagacg aatattattg
    23641 ggcaatcctt cttttttttg ttatgataca tgtgaaatct ttcgtaaagg agaaagaaaa
    23701 tgcgcaaagc tcaaagacat ttgctgatta aacaagtcat tgaagaattc ccgatccgta
    23761 cgcaagaaga actattaaac aaacttgggc attatggcgt taccgccacg caggcaacga
    23821 tttctcgaga tatccgtgat ctaaaaatcg tgaaggcacc tgatgaaaat ggcgtttccc
    23881 gcttcgtatt gtttcgcgaa aaaggaactc ctgagactag gactgaggaa gaggatcggc
    23941 tggttcaaat gattgaagac attgtattga aagtcgaacg agtccacttt ttgacgatcg
    24001 tcaatacctt gccagacaat gctcatttat ttgcatctgt tttagatgag atcaaacctc
    24061 cctctattgt cagtacaatt gctggattcg atacgatcat ggtcatctcg gaaaatgagg
    24121 aggacgcaaa acgagtagaa gaatttcttc accatccaac tgaagtatca cttttttaat
    24181 cagagcacgt attcctaata tggaatgcgt gtttttttat tttcaatatt ttccttattg
    24241 aataaacctt tacactcttt acaaaaatac atcatttttt attcaaattt ttcaacacct
    24301 tgattgaatc acaataatca tcatttatat tggatgttaa caagagcagc ttcttgctct
    24361 ttgtgtattt caaaaaagaa atgaaaggaa atcatatgta taaattatta acttctggac
    24421 cattgacgac ttctgaaaca gtgaaaaatg ctatgctgat cgatcattgt acttgggatc
    24481 aagaatacaa agaaattaca caatggataa gaaaaaaatt attggatctt gctcaagtat
    24541 cggaaggaat atacacaacg gtcttaatgc aaggtagcag ctccttcggg gtagaatcgg
    24601 tattaagttc tgtgatcagg ccagaagata ctgtactgat ttgttcaaac ggcgcatata
    24661 gacaacgaat gatcaacatg tgcgaatgtc tgaaactgaa ctataccgtt tatgaggtat
    24721 cggaacatca aatcctccaa gctcatgtga ttacacagct gattgaagag aatccgtcta
    24781 tctccgcact agcaatggtc catagcgaga ctacttccgg tattttgaat aatttggaag
    24841 agattgctgc tgtcacacaa gaaagagatc ttttgtttat agtggacgcg atgtcaagct
    24901 ttggtgggat accgatttgt gtagccgaac tagggattga ttttttgatt tccagctcaa
    24961 acaaatgtat tcaaggtgtt ccaggctttt cttttgtact tgctaataaa gcggaactgg
    25021 aaaaacgaaa aaatgttagc cgaagtttgt cacttgatct atatgaccag taccgcgtga
    25081 tggaaaacga gaatggcaaa tggcgtttca cttcccctac ccatacggtt ttggcttttc
    25141 aacaagcgct gaaggaacta gaggcagaag gaggaatcga aactcgatat tcacgttatc
    25201 tcgccaataa tcatgtgcta cgacaaaaaa tgacagagat ggggttccag cctttcattc
    25261 aagaatatca ggggccattc atcacctctt ttctttaccc taaggactgg cgatttgatt
    25321 ttaatcattt ttatcagtat ttaaagcaaa atggatttgt gatctatccc gggaaaatca
    25381 gcgatcatga atgttttcgt atcggaaata ttggcgagat ctatccggaa gatattttgg
    25441 aactgacagc aattatcaaa gactataagg agaacgttaa tgattaaaac tgtaattttt
    25501 gattgggcag gaacaactgt ggactttggc tgtatggctc ctgtccacgc ttttagaaat
    25561 gcttttctag aaaaaggaat ccaactgact gacaaagaaa tccgctaacc gatgggaaaa
    25621 ttaaaatggg atcatatcca acagcttctt tccctccctt ctgtcaaaaa acaatggata
    25681 gctatttatg gacaactacc tcaggaaaaa gaggtggagg aattgtatca acaatttgaa
    25741 cattatctgt ttaaagattt ggtcaagcat tctaccttga aacccgacac attggaaacg
    25801 atcgaacggt tgagaaacgc tgggatcaat attggttcca cgaatggatt taatgctcct
    25861 atgatgacaa tcgtagcaga aaccgcaaaa aaagaaaggt attcaccaga cttcatggca
    25921 acttttgaag acgtcgaagg gtatggtcga ccgtttcctt atatgatcca taaaaacatg
    25981 cagtacttca aaaacaagtc ggttgatgaa gtaatcaaag tcggagatac ggtctcagat
    26041 atccaggaag ggaaaaatgc cggagtgttg acagtaggtg taattgaagg tagttcgcta
    26101 atggggattt cttatgatga gtaccaaaaa ttagagatgg ggaaaaagat cgtttaaaac
    26161 agtctgttgc tcttagattc caacaagccg gcgctgatat ttgtgtaaac aatttaaaag
    26221 agttaacaga atacattttg tacgctgaca tgaatccaga atgactttta tacaaaataa
    26281 gaggttgtga aaaagctgtc ctgtatcaag taataaaaac agccaagcaa aaatagctcc
    26341 tcatattttt cgtttggtta ggcttattac cgcagatgca agcttttgaa caccgtttat
    26401 tcgaaaaaaa aaagggagct gtgacacgac ttttgtcaca gtccccttat ttgcaaacaa
    26461 acagtgttta agagacaacc tctccactaa acggtgttca ttcagctgac tctcggtatt
    26521 tgctcaaaaa acgataaaat ttgaaaagct attttctctt ttgtttctct aatactcgga
    26581 tcagaacgct gatttcacat tctctttttc ttacatctta tctggtgcat gaagtcctag
    26641 caaacgaagg tcttctttca ataatacagt cactgcataa actagagcta agcgtgcttc
    26701 tttttgttca tcatcagcta aaatcttcgt atgagcatag tatttgttga atgcttgtgc
    26761 taatttgatt gcatgtttcg caatcactga cggttcgtat ttttccccag cagacaagac
    26821 cgtttcaggg tatttttgaa ctaatttaac cacttcccag ctggtatcgt cattcaatgc
    26881 atagtctgct gtttctgaag ggacaaatcc tgctttttcc aacaggctga ctgcacgagc
    26941 atgtgtatat tgcacataag gtccagtttc tccttcaaat cgaacaactt cttccaggtt
    27001 aaagtcaaat gtattcagtc gatcgttttt caaatcgtgg aaaatgactg ccccaacccc
    27061 aacttgttta gctacagcat ctttgttttc caaatcaggg tttttctcgc tgatttgttc
    27121 tttagcagat tggattgctt catttaatac ttcttctaat aagacgatct ttcctttacg
    27181 agttgataat tttttaccac cttgcgtgat caaaccaaat ggaatatggt gcatgtcgtc
    27241 agaccagtca aagcccattt ccttcaagac agctttcaac tgtttaaaat gatagctttg
    27301 ttcattccct actacatata gagattgttt gaagtcgtaa gtacgtttac ggtacaatgc
    27361 agcagctaag tcacgtgtaa tgtatagtgt cgcaccgtct gacttcttaa tcaacgctgg
    27421 attcaggtca taagcagata ggtcaacgat ctctgcacct ttatcctcgt tcagcaaatg
    27481 tttttcttct aaaagtttga cgatttcatc catcttgtca ttgtagaaag cttcaccgtt
    27541 caacgaatcg aaacgtactt ccagcagatc atagatttta ttgaattctt tcatcgattc
    27601 atcacggaac cattgccata attgaatagc ctctttatcg ccttcttcca gacgtttgaa
    27661 ccaagcacga gcttcttcat ttaattctgg ttctgtttca gctacttcat ggaattggac
    27721 gtataaacga agcaattcat tgattggttc tgctttaaca gcttcttctg taccccattt
    27781 tttgtaagcg acgatcagtt ttccaaactg tgttccccag tcacctaaat ggttgatgcg
    27841 gattggctga taaccgattt tttccataat gaaaccgatc gaattaccga taactgtcga
    27901 acgcaaatgt cccattgaga ttggtttggc aatattagga gaagacatgt cgattggtac
    27961 tgttccttga ttcccgatgt tgctatcccc ataatgttct ttttctttca ctactgtttg
    28021 caaaactttt ttgctgataa gttctttatt catgaaaaag ttcaagtaag gtccgacaac
    28081 ttcgattttt tcaaagttgg cagaatcgat tttttctgct aaatctgcag cgatttgctg
    28141 tggcgctttt cggtaaactt ttgctaatga aaaggctgga aatgcaacat ctccgtgttc
    28201 agctgatttt ggattttcta gtaattgctc gacttgttcc agtgttaaat catctttgac
    28261 agcgtcatag acagcttttg cgacaagatc tttattattc atctttattc ctcctaaagt
    28321 gttcccttga ttgttaaaca aaaaaaatct ctagcgacgg catacttagt atgccatcac
    28381 tagagacgag atttcccgcg gtaccactcc aattgtccta aaaaaggacc agctccatct
    28441 gatatcggta gacgaccgtc tgtttaaaac agaattctcc aagtgcgctt cgttgtatct
    28501 tcttcattcg gcttccacca cttccgaatt cgctagccaa gaatgataca agtactctct
    28561 tgttcaacaa atcttagtct tattaaactt tcttgaatta tatcagaaaa aaaaacgaaa
    28621 ggctagtcgt ttcataaaaa aacaatccag atggcctaaa ggagaagaaa taccacctgg
    28681 atagctataa atcatttcgt aaatacgaaa gacttaacaa attaatcagc tacgataatc
    28741 gttccttctt cagaagctaa aagattctcg atattttcta aagaagtgat gattgcctta
    28801 gcgtttggtt ttgcttcaac aaatgcaata gctgcttcta ctttcggaag catgcttcct
    28861 ggagcgaatt gcttttcatc aatgtattgt ttcatttctg aaacagtaac agtttctaat
    28921 ttcttttgat ctggtttttg gtaattgaca tacacattgt ctactcctgt caatacgatc
    28981 agcaaatccg catcgatgat ttcggctaat ttttctgaag caaaatcttt atcgattacg
    29041 gcttctcgtc cttctaatcc agtagctgtt tctacaacag gaatcccacc gccaccaaca
    29101 gagactgtga taactccttg atcgaccagc gtttcgatga cacgtgcttc tttaatcgag
    29161 atgggtttag gggaagcgac tacttttctc catccacgtc cagcatcttc tttgaatgtc
    29221 acagtggagt cagcattcat ttgttctttg gcttcttctt ccgtgtagaa tggaccgact
    29281 ggtttacttg gatttttgaa tgaaggatca ttttcatcca caataacttg agtgactaaa
    29341 gaaaccacat ctttatcgat ccctttttcc ttcagtactt cgcccatggc gttttgtaac
    29401 cagtaaccga tagatccttc tgtcattgca acacatgtat ctaaaggcat tgccggtgtt
    29461 ttctcagaat cagcagcttg ctgctgaatc aataggttac cgacttgcgg accatttccg
    29521 tgggagatga tcaattcatc tccttgttcg ataaatttca ctaaatactt tgctgtttcc
    29581 attaacgctt cttgttgggc ttttgcactt gcatccgtag acaagatggc attgccccct
    29641 aaagcgacaa ctacttttcg tttggccatt tcattcgtcc tttcttcagt tctaccgaat
    29701 tttctagata acaaaacgag ccagcgtttt gtgattttcc ctcaatgctg actcgttttt
    29761 tcgtgagatg aatgtggtta tgcttaaacg cgagggataa acaagttacc taatgttgct
    29821 gccatgatcg ctttgattga gtgcatacga ttttctgctt ggtcaaattg acgagcatat
    29881 ttgctgcgga agacttcatc tgttacttcc atttcagtga tgccaaagcg ttctttcatt
    29941 tgttcaccgt aaacagtgtt tgtatcatgg aaagctggca agcagtgcaa gaagatcaaa
    30001 cgatctgtgt tgtgtgtttt ttctaccatt tccatattga tttggtaagg tttcaacaat
    30061 ttgatacgtt cttcgaattt atcttcttca cccattgata cccatacatc agaataaagg
    30121 acgtctgctc cgtctacacc tttatcaaca tcgtcggtaa tcatcaattg tgcaccggat
    30181 ttttcagcaa agccttctgc cattttgacg atttcttctt caggttgtaa ttcttttggt
    30241 gcaacgatac gcatattcgc tcctaaaatt gcacctgtga ctaataaaga gttagccata
    30301 ttgtttcgac catctccgca gtaagcaaca gtgatacctt ctactgttcc aaagttttct
    30361 tggatagtta aaaagtcagc gatcatttgt gttggatgcc attcatcagt caagccattc
    30421 caaactggaa caccagagaa ttctgctagt tcctctacca ttttttgact gaatccacgg
    30481 aattcgattc cgtcaaacat acgtcctagt actttagctg tatcttctgt ggattctttt
    30541 ttacctaatt ggatatcatt tgcacctaga tattcaggat gtgcacctag atcgatcgct
    30601 gcagtagtaa atgcagaacg agtacgtgta gatgtttttt caaataaaag cgcaatattt
    30661 tttccttcta gatagtgatg tgggatacca cgttttttca agtctttcaa gtgttctgaa
    30721 aaatcgatca aatattgtaa ttcttctttt gtaaagtctt tttctgctaa taagcttctt
    30781 ccttggaata ctgattcttt catattaaac attctccttt agattgtttt tatttaagat
    30841 taaagaggaa atcccgacgg cagctgacag taagactgcc gtcaggaaac aaattacttc
    30901 aagtcttcac ggacaagtgg ttggctcatg cagcgtggac caccacgacc tcgtgacaat
    30961 tcacttgaat tgatttctaa cactttgatg ccatagctac gaagcaattc gttcgataca
    31021 taatttcggt tataagtgac tacaacacct ggagcgattg ccaatgtgtt tgatccatca
    31081 ttccattgtt ctcgaggtgc aacgatctca tctccattac cagttgggat cagtacaaga
    31141 tcatctaatc caagagcagc tttcatcgtt tcgtgtaagt tatctgaatg agtaatcttg
    31201 atatcatcac catctggttc gattgtaaag acatccatct taccgtcttt actttgaatt
    31261 gctggatgga tagtgaattt atcgtgatct accattgtaa atacggtatc caaatgcatc
    31321 attgcacggt tgttcggaat tttgattgcc aacacttttt caaatcctga attttttgcg
    31381 aataggtggc gtgctaattt ttctaaagct ttcgcattag ttcgttgaga aatcccaaca
    31441 gctactactt tatcgcttaa gatcaattcg tctccgcctt cgatatgatc tggattttca
    31501 cgatccaacc atacttcgat tcctttattt gcaaatcttg gatgatgttt caaaatatat
    31561 tctgtaaaca tcgattcacg acgacgtgct tcaaaagtca tcttattgac tgtcatccca
    31621 tttcccattg atgcggaagg gtcgcgtgta aagtacaagt ttggcattgg gtccatgtaa
    31681 aatggatagt catcgtctgc tgacagatca tatagactgc tagaacgtac ttcgatatct
    31741 tttgtacgaa ccccagccat gattttatct accatttctt gcgtttccat tgatagaagg
    31801 aactcatgaa gaccctctct tacagcattc gatgcaatat gagattcatc caacatttta
    31861 ttcaagaatt gttctttgac attgcctgcg tcaatcgctt ctgccgctaa tttttccaag
    31921 taaagagtct cgacgccttc attttgcaat gtcttcgcaa agttgtcatg ttcttcttga
    31981 gcaatcggaa gatatggaat atcatcgaac aacagacgat ccataatatc tggtgtcaaa
    32041 ttttccactt cttgtccagg ccgtttcagt aaaactgtct ttaatttccc tatttcagag
    32101 aaaacgtgaa taggtttatc catgttgtgt tgcctccttc tttttgatta catgtatagg
    32161 atatcctcct tttgtaatca ctttcataat tttgtctcat tcaaaatgag acattcctca
    32221 cattaatatt cgataattaa ataattaaac gtttttctat ttttaagcgt aatttattca
    32281 ttttttattc tgtatacact ttcaaaaaaa tatttattca ttgaaaaaat ttttttgaat
    32341 aaattaaaaa aataaattat at
//
LOCUS       DADVXV010000026        30257 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.026, whole genome shotgun sequence.
ACCESSION   DADVXV010000026 DADVXV010000000
VERSION     DADVXV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.026"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            35..733
                     /locus_tag="KB969_001125"
     CDS             35..733
                     /locus_tag="KB969_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBB6869127.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(901..3540)
                     /locus_tag="KB969_001126"
     CDS             complement(901..3540)
                     /locus_tag="KB969_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6869128.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(4159..5190)
                     /gene="queA"
                     /locus_tag="KB969_001127"
     CDS             complement(4159..5190)
                     /gene="queA"
                     /locus_tag="KB969_001127"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBB6869129.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            5383..6558
                     /locus_tag="KB969_001128"
     CDS             5383..6558
                     /locus_tag="KB969_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6869130.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            6562..7203
                     /locus_tag="KB969_001129"
     CDS             6562..7203
                     /locus_tag="KB969_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869131.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            7200..8117
                     /locus_tag="KB969_001130"
     CDS             7200..8117
                     /locus_tag="KB969_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6869132.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            8114..8785
                     /locus_tag="KB969_001131"
     CDS             8114..8785
                     /locus_tag="KB969_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869133.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(9326..9814)
                     /locus_tag="KB969_001132"
     CDS             complement(9326..9814)
                     /locus_tag="KB969_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBB6869134.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(10015..10281)
                     /locus_tag="KB969_001133"
     CDS             complement(10015..10281)
                     /locus_tag="KB969_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6869135.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(10281..10544)
                     /locus_tag="KB969_001134"
     CDS             complement(10281..10544)
                     /locus_tag="KB969_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6869136.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            11020..11205
                     /locus_tag="KB969_001135"
     CDS             11020..11205
                     /locus_tag="KB969_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6869137.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(11347..13170)
                     /locus_tag="KB969_001136"
     CDS             complement(11347..13170)
                     /locus_tag="KB969_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBB6869138.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(13768..16473)
                     /locus_tag="KB969_001137"
     CDS             complement(13768..16473)
                     /locus_tag="KB969_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBB6869139.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(16779..17726)
                     /locus_tag="KB969_001138"
     CDS             complement(16779..17726)
                     /locus_tag="KB969_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBB6869140.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            17916..18185
                     /gene="rpsN"
                     /locus_tag="KB969_001139"
     CDS             17916..18185
                     /gene="rpsN"
                     /locus_tag="KB969_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6869141.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(18361..18723)
                     /locus_tag="KB969_001140"
     CDS             complement(18361..18723)
                     /locus_tag="KB969_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6869142.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(18734..19855)
                     /locus_tag="KB969_001141"
     CDS             complement(18734..19855)
                     /locus_tag="KB969_001141"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBB6869143.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(19871..20221)
                     /locus_tag="KB969_001142"
     CDS             complement(19871..20221)
                     /locus_tag="KB969_001142"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBB6869144.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(20351..21862)
                     /locus_tag="KB969_001143"
     CDS             complement(20351..21862)
                     /locus_tag="KB969_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBB6869145.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(22184..23536)
                     /locus_tag="KB969_001144"
     CDS             complement(22184..23536)
                     /locus_tag="KB969_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBB6869146.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(23689..24765)
                     /locus_tag="KB969_001145"
     CDS             complement(23689..24765)
                     /locus_tag="KB969_001145"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBB6869147.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            24961..26706
                     /locus_tag="KB969_001146"
     CDS             24961..26706
                     /locus_tag="KB969_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBB6869148.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(26986..27423)
                     /locus_tag="KB969_001147"
     CDS             complement(26986..27423)
                     /locus_tag="KB969_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBB6869149.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(27407..28780)
                     /locus_tag="KB969_001148"
     CDS             complement(27407..28780)
                     /locus_tag="KB969_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869150.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(29102..29590)
                     /locus_tag="KB969_001149"
     CDS             complement(29102..29590)
                     /locus_tag="KB969_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6869151.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(29612..30214)
                     /locus_tag="KB969_001150"
     CDS             complement(29612..30214)
                     /locus_tag="KB969_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6869152.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         8673 a         6465 c         5623 g         9496 t
ORIGIN      
        1 tattggtgtt attaaagaaa aggagggaaa aatcatgcaa tcttctgcag aattaaaacg
       61 ccaagcaaaa gagagtctaa aaggacgttg gggacaagct gttttactaa atctaatccc
      121 tacattgatt ggtattgcta ctattcttct tattatgatt cctattatct tgtttgccac
      181 caccatatat gatggatcag cgagcgtctc agaagcgaca acttcaggag gcggtagttc
      241 aggaggcggt ggcggaatta tttccagcat cattagcgct ttgttcatga gcggtatttc
      301 ttggacttat cttgatattt tacgtggaca aaaagatcag atcgaaccat tcaaagatgc
      361 atttcgtgga ttcaaaggtt tgtttatcgg cggagtgatc agcttagctg tgctgatctc
      421 gatctttaca acattatggg gtttgctatt agttattcct ggaatcatta aaagctattc
      481 ttattctcaa agctatttta tttactacga tatcgtccaa gaaacaggac aaacacctaa
      541 agtactggat acgatcactg caagtcgaaa attgatggat ggttataaag gacaactttt
      601 ctggttagat ctttcattta tcggctggca tatcttagca ttagcaactg ctggtattgg
      661 ttatctatgg ctcagcccat acatttctgc aacaaaagca gcattttatg aacaattgcc
      721 aaaagatatt taaaagagag tgtgacttgt gaccgagggg gtggcaggag aacaccgttt
      781 atcgagaggc agtaaaagaa acattcagcc cattagcaaa aaggaggtgt gacaacattc
      841 atgtcacacc tcctttttgt atagttccag taaaaagaaa atcaacttag aaacagttaa
      901 tcattcctct tcttctgctt ccggtaatcg atggaacttg atcagttcat tcaccgcgat
      961 tggtacgata gataaaatcc ctaccaagaa ccagtgattc aaactgatgt gtactaggcc
     1021 gaatagttct tgcgtaaatg gcagcaaagc aacagccgtt gtaatagcta atgccagtaa
     1081 cgccatttct accaaagctt tattggtcgc taaattgact ttgaagatcg attggctgct
     1141 gcgtacattg aacacatgca gaatcgatga ataagctaag atcaagaatg caacagtttg
     1201 accgacatgc tgacttgcgt ctacccatgg gctgatagta tcgacataac tacctaaata
     1261 ataaccaaac aaggttacga tggtgaagac ccctgcattt atggcaattt tttgcaataa
     1321 acctcgagca aagatccctt catttttcgg aatgggtggc tgatccatga tgccgtgttc
     1381 cgctggctct cttcctaaag caaatcctgg aagtccatca gcaactacat tgacaaacag
     1441 tagttgcaca gctgtaaatg gtgctcccca tcctaacagc atcgcaatca aaacaataaa
     1501 gatctccgaa atattacagc ttagcaaaaa gttgatagct ttacgaatat tctgataaac
     1561 cgaacgtcct tgactgacag cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat
     1621 atctgcggca ctttgcgcca catctgttcc tgtgatcccc atggcacacc caacgttact
     1681 tgctttcaac gctggtgcat cattcacacc atccccagtc atcgctacga ctgcacccgt
     1741 acgttgccaa gatttgacga tccggatctt gtcttctggc gttacccgag catagacaga
     1801 gagagctttg acacgcgcat ctaattcttc gtctgataat tgatgcagtt ctgatcctga
     1861 aagtgcttct gacggatcat tcaagatacc taattctttc gctatggcac tggcagtcac
     1921 cacatgatct ccagtgatca tgactgtttt gatgccagcc tttttcgctc gcttgattgc
     1981 tcctttactt tctggacgtg gtggatcgat cattccgatc agaccaatca aacgtaagtc
     2041 tttttccagt gcttcagaag aaatatcttg cggttcttcg tcataagtag cataaccaac
     2101 agcaatcact ctcagtgccc gtttaccaaa gcgatcatta acgatcgccg cttgttctac
     2161 atcgcctgaa ctaaagcgcg gagcaagaac atcgaatgct cctttggtga ttgagatgta
     2221 tttttcgccc atttggtgaa ctgttgtcat catttttcgt tcagaatcaa aaggaagctc
     2281 gtttactcgt ggatattttt cttctaattc tgcctttgta tgataattct cttcaacagc
     2341 ccttacgatg gctacttctg ttggattacc tttgataaca aggtcgtcat cttcttgctc
     2401 gaccgtcaca tctgtacata gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat
     2461 tgaatcttcg atattcgtta cttcatcttc tttgctccat acccggcgga cgcgcatttc
     2521 attttgtgtc agcgttcctg ttttgtctga gcagataaca ttagcggttc ctagcgtttc
     2581 aactgctggc aactgtcgga tgatcgcatg tttcctcgcc atcttctgca caccgtatgc
     2641 aagtgtcaac gtaacaataa cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat
     2701 cgaagtcatg aacatctcaa ggagtggttc tccttgcagt tcaccaatca caaatactaa
     2761 agccgcagcc gctaaagcga tcatactgat tcgtttgcct agctgattca atcggacctg
     2821 taaaggtgtt ttttgcatag tattttcgtt caaaagatcc gcgatcttac ccatttctgt
     2881 agccatgcca atggcagtga cgatcgcttt cccacgacct gcagcaaccg tacatccttt
     2941 aaataccata ttaagttggt cacctaatga ctcatcttct tcagcaataa atgctgcatc
     3001 tttttcaact gcttcacttt ctccagtcaa cgccgattct tctacacgta attgtgatgc
     3061 ttcgatcaaa cgggcatcgg cagaaatagc atcaccggac tctaaaacaa gaatatcacc
     3121 cactaccagt tgctctgact caacagtggt cactttgccg tctcgtatga cagttgccgt
     3181 ttgtttattc atatcttgca aggattccag tgctttttct gcgtttcctt cttggacaat
     3241 cgccaatacc gagttgatca caacgatagc gatgatcagc agtccttcaa ataaatcccc
     3301 atgttctgta gcaaatgcgg tataaaagga aatcaccgct gctacaagaa ggatgatcgt
     3361 tgtaaaatcg gacaagcttc gaaagaattt tttgatcatc gattctttcg gcgcctcatc
     3421 gaatttattc aatccctgct tttttcgccg ttcatccact tcttgtgaag acaacccagt
     3481 atctggatct gcttctgtta ccttctttac ttcttctatt gtctgcttgt attcttccat
     3541 cctattcctc ctttaaaatc ttcgtacaaa aaaaggtact tattttacta taacatcctt
     3601 tttttattta cttcaaataa agggcttatc gattatttgt taagaaagcg taaaatttaa
     3661 agtgcttata tttgcaaacg ctaccaaagg atgctattat atagatgtaa ggaaggagga
     3721 taccatcaaa tagacagaag aatttctcga tagaacagtg taagcaaaca aagttgttag
     3781 aagtacaggt ttcacccaga catgcgtgta gagtacaaac ctataaatag tgaatgcgta
     3841 tggatgtttg gatcacgaag tatccgaaac aagaagtaat gcgatacgta acaattgaat
     3901 aacgtaaacg tctgaaaatt gaataggaac aagagatgtt tcaaatgttg aagatgtaac
     3961 gaaaacaaaa tttttgttta acatgaagaa attcaacacc gtgctttgca tgtatgatgg
     4021 aaagttacaa tcatttctgt ttatttgaat ccttccgagg tacaagaaag ccgagcttat
     4081 cgagagctcg gctttttctt tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac
     4141 tagcggcttt tcataacctt atttcacgaa catcgcatct ccaaaactaa agaaacgata
     4201 gcgctcttca atcgcatgct ggtaagcaga taaagtcaat tctcttcctg caaaggcact
     4261 aactaacatg actaaagtcg attttggcaa atggaaatta gttgagaaag cttctaccac
     4321 tttgaattca tagccaggcg taatgaaaat atcagtccat ccgctgtctg ctttgatttc
     4381 tccattaaat ttcgttccaa tcgtttctaa tgttcgaatt gaagttgttc cgacagccac
     4441 gattttcccg ccatttttac gtacttggtt caatcgctca gccgcttctt ccgtcaaacg
     4501 gtagaattca ctatgcatat ggtgttcttc aattttatct acgctgacag gtcggaatgt
     4561 acctaaccct acatgtagtg tcagatagac taattcaaca ccctttgctt cgatctcatc
     4621 aagtaattct ttcgtaaaat gcaatccagc tgttggcgct gcagcagaac cattttcttt
     4681 cgcatagaca gtttgatagc gatctgggtc ttccagacgt tctttgatat atggaggcaa
     4741 tggcatttct cccaatgatt caagaatctc tagaaaaatt ccttcatact caaagtcaat
     4801 gatccgtccg ccgtgttcca attcttcttt cactactgct tgcaatctgc catcaccaaa
     4861 agagattctt gtcccaactt tggcacgttt cgcaggtttg atcaatgtct cccacgtatc
     4921 tccttgtgta ttcgttagaa gaaggacttc taaatgcgca ccagtatctg gtttttctcc
     4981 atataaacga gcaggcagaa ctcgtgtatt attcataact agcgcatcac caggctgtaa
     5041 ctcttcaatg atttcatgga aatgtttatc ttccatctct ccagttttcc gatccaaaac
     5101 aagtaaacga gaatgatcgc ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa
     5161 gtcaaaatca aaatcttctg ttgttaacat atcgtcactc actttctatc atgtgcttca
     5221 tcattctatc atgtttttcg ttctgttggc aaaatcagca ctttttcact tctatttttt
     5281 gttttcctaa ataaaaaaac taccctattt gtattttttc attgttttag gcatactagt
     5341 aatagatagt tcttcattga aaatagaaaa agaggtggca ccatgattga atttcaaaat
     5401 gtgtcaaaaa tttataaagg tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa
     5461 aagggtgagt tcatttgttt tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg
     5521 atgatcaacc gaatgactga tccaacacaa gggaaaattt tgattgatgg aaaatccatc
     5581 caagaaattg atccagtgga attgcgacgt cagatcggct atgttatcca aagtattgga
     5641 ttgatgcctc acatgacgat ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc
     5701 agtcaagaag aacggaataa aacagctgaa aaaatgattg atcttgtgga attgccccgt
     5761 gagatgttag atcgctaccc acatgaatta tctggtggtc agcagcagcg tattggagtc
     5821 gttcgtgccc ttgcagcgaa tcaagatatc atcttgatgg acgagccatt cggtgcgctt
     5881 gatccaatca ctcgtgattc cttgcaagac cttgtcaaag atttacaaga gcgtttggga
     5941 aaaacgatcg tatttgtaac ccatgacatg gatgaagcga ttaaactagc aagccgtatc
     6001 gccatcatga gtgaaggccg tgtgatccaa tttgatacac cagaaaatat tttacgtcat
     6061 cctgcaaacg atttcgtaga agagttgatt ggagaagatc gcctactaca agccaagcca
     6121 aatgcgacaa gagtcggcga agttatgcta aatacagcaa tcacgattac accggaaaaa
     6181 tcattacaag aagcaatcaa actgatgagg gaaaaacgtg tagatacgtt gttagttacc
     6241 gataattcga atgtattaaa aggatttatc gatgtagaaa cgttgaataa aaaacgagga
     6301 aaagtatcca gtgtcggcga cattttgaat aaacatgttt tttacgtaaa agaatccgcc
     6361 tatcttcgtg ataccttgca acgcatttta aaacgcgggc tgaaatacgt gccggtcgtt
     6421 gatgaacaga acaaagtcgt aggtatcctg actcgtgcat cattagtgga tatcgtctac
     6481 gatgtgattt ggggagaaga tcccgcaact actgatgttg cagagtcagc tactcctgaa
     6541 gaatctaagg aggtctgacc tatgcagcag ttttttcatc agcacggttc agaaattctc
     6601 tcaaaaggtt ttgaacatct ttatatttca ggacttgctt tgatcattgg tatcatcatt
     6661 gctgtaccgc ttggtgtctt actgacacgt tttccaaaag ctgccacgat tgtgattggc
     6721 ttaaccagtg ccttgcagac aatcccttct cttgctttat tggcattgat gatcccgcta
     6781 tttggcgtag gtaaattacc tgcgattatc gcactcttta tttattcatt attgccgatt
     6841 ttacgtaata cgtacattgg gatgaaaaat gtcgattgga attatcggga tgtggcaaaa
     6901 ggcatgggga tgactgagtt ccaatccatt ttttccgttg aattgcccat tgctatgcca
     6961 acgatcatgg ctggtattcg tttagctgcc gtttacgtga ttgcatgggc tacacttgcc
     7021 tcttatatcg gcgctggtgg tttaggcgat ttgattttta gtggactgaa taattaccaa
     7081 ccagatctca ttttggcagg tacgatccct gtaacaattt tagcactatt ggctgattgg
     7141 cttctaggtc tcttggaaca ccggctgaca ccgatcgcac ttagagagga gaatgaagaa
     7201 tgaaacgtat actaaaaatg accatggttc ttttctctct tcttatactt gcgagttgtt
     7261 ccttccctgg tcttgccagc aatacagatg aagacaccat ttcgatcaca ggtggaatca
     7321 cttcagaagc acagatctta gcaagtctag ttgccggaat ggttgaacat tatacagata
     7381 aaaataccgc aatcatcaac aatctggcta ctacaactat caaccatcaa gcgatgatga
     7441 acggagatgc ttcaatttca gcggctcgct acacaggaac agatttaacg actacattga
     7501 accttcctcc tgaaaaagat ccgaaaaaag cgtttgctac cgtgaaagat gaatttgaga
     7561 aaagatacgg tcaaacgtgg ttcccgtcct atagttttga aaatacgtat gtctttcttg
     7621 ttcgaaaaga caccgcacaa aaataccatc tatctaaagt cagcgatctg aaaaatgtag
     7681 cggatgaatt agtagctggt gtagatactt cttggatcaa tcgtaaagga gacggttatg
     7741 acggcttcca agaaacttat ggcttctcct tcaattcgat attacctatg cagattggac
     7801 ttgtttatga cgcagtcgaa gcaggaaaaa tggatattgt tcttggctac tctacggatg
     7861 gacggatcgc cagttatgat ctagtcatgt tggaagatga tcgtcaattc ttcccaccat
     7921 atgatgctgc tccagttgta gacaacaaga tattagctga tacgcctcat ttaaaagaag
     7981 ccttaaataa gttaggtcat accatcagta cggaaaaaat gcaggaattg aactacgaag
     8041 cagataataa tctagtggaa ccatcagtag tagcacaacg tttcttacaa gaaaaccact
     8101 attttgaagg gaagtgaagc aattggataa aatgaatgtc tttcaacaat ttttctatta
     8161 tttccaggaa aatggctcct atatctttgc acaatttatc cgtcacttcc tgatttctat
     8221 ctatggtgtc ctctttgcag cagttgtcgg gattccggtt gggatcatga tttctaggag
     8281 acgtaaatta gcaaactggg tgattcgttt ggcgaatatc atccagacga tcccttctct
     8341 agccatgatc tccattttaa tcattggatt aggcctggga gtcaatgtcg tgattgttac
     8401 tgtatttttg tattccctct taccgatcat caagaatacg tataccggga tgatccaagt
     8461 agacaaaaac atccttgatg tcggcaaagg catggggatg actgctagac aacgactatt
     8521 catggtagag ttaccactct ctgtttctgt tatcatggca ggcataagaa acgcgttagt
     8581 tgttgccatc gggataaccg cgatcggtgc attcgtcggt gctggtggtc ttggagatat
     8641 cattatccga ggaaccaatg caacagaggg cacatcgatt attttagcag gtgcattgcc
     8701 aactgcatta atggcgatca tcacggactg gcttttaggt attttggaaa gacggctaga
     8761 tccagccagc cgtacatcac gctgatgtta ttgtaaaaaa caaaagcttc tgcgaccatt
     8821 tgttggtcgc aaaggctttt ttagttctgt catttttaag gcaataatcc actctgattc
     8881 ttccctcctt atgggcaaag agttgctttt cttagctatt tatccattcc gtatactcca
     8941 acttcatact gccaacgggt tcatatctgc atccaccgac taagtttttt tcttatccgc
     9001 taaggcattt tgccaatcca ttttcccatc actcgtcatg gaattcatac cacatgatct
     9061 ctaaatactc gtctgcttgt tctttgaatt gggcatcaat tcttacatcc tttggcgtgg
     9121 ctttcattta agccttttcc atcagtcctc gattgttcga tgccttcagc tgcatcatca
     9181 aaactggtga ctgccgtatc ggtaacttcg atcatctttt atacaatcgg gaacttgcca
     9241 tcctcatcct tggctaaaaa catatctagc cattccagct tctcgccatg ggaggtttgc
     9301 ggttcctaaa accggtacac gattcttatg gactgcatcc gtcgcaacta gacttggcga
     9361 tacgatgatc cttcaccaga agagcacccc cgtaaaccaa ttgatcgata tattgccaat
     9421 aagaaaagac attggcgtaa aagatatcga tccctcgtga tgcattgccg ttgatactgc
     9481 tattcatggc cgaaagcgcc acgactttaa cttcttccgt ttgagtgaca ttcatgttcg
     9541 gcaatgtcgc tttggatacc cgctctgcta aaggaacgac actggtattg tatttcgtat
     9601 ctgtatcttt tccaaaagac catgccaacg aatcctctgg gaaccaataa gacgactccg
     9661 gttgattgtc cattgctttt ttcaacatac ttttggctgt ttctcgataa acgacatttc
     9721 caattgtctt cgcctcactt tggcgataat cgatggtcgt tgccactgcc aacactaaca
     9781 acgatgctcc aattttactg attttccttg tcacacttct tcctccttgt tttacataaa
     9841 cccgtcaaca ttccattcct aaactcaaac aatgaccctt caaaggtgga gatataggaa
     9901 caaattaaag aaatcatgca ataaatccaa gaaggttggt tttagaacaa aaaaagagtc
     9961 tcctttttgg ggagactctt tgttaactat ctaaaaaggt tggctcttct cacttcactc
    10021 ataatgtgtc caggcagaat aaatttctac aactttattt tcctcatcaa ctttgtaaac
    10081 cactcgatgc tgtctattca gcctgcgtga gtatctgcct tcatgtgtag gtctcagctt
    10141 ttcaaaagac tgcgtgggca tatatggatc ttccttcaat gtctgaatca cttcttcaaa
    10201 ttgtttcttt aaattcgttt gcttgatttt tcttaaatcc actttcgcag agtttttgat
    10261 tgcgactgta tagttactca tcaaagagct tcccaatcaa tatcatcgat attcgtaaag
    10321 ctactgtcgt ctttttcgcg gtctcgtact ttatctaaag tacctgtttg ctcaagaaaa
    10381 agggtttctt gaatcgctct ccagtcttcc agcccaatca atacagcatt gtttccacta
    10441 cgatcactaa taatctcgat ttcagtatga ttttcattta cctctttcaa taactgataa
    10501 aaatttttac gagcagtgct aggattcatc gttgtattag ccattgtctc tcctcctttt
    10561 tctgatataa ttatagcgta cttgattaag tacgtcaaaa aaatacaata aagcacttaa
    10621 attcagcaaa cttttcctct tttttacata gagaaaaaga ccccttttta gggaggatct
    10681 ttgtccacgc tcacttctta ctcctttacg actagcggta gccaaacgta aagtaattgg
    10741 taacaacgta tcatctttag caaaggtcga atccaaagcc tgtgagtcta tgcaacaaca
    10801 ccaatacacg aaggttcctc gttgcagtgt gacttgattg atatcttgaa taacctgagg
    10861 atacgcacga aagatttgta acggttattc aaaactgatt ttggccgtca agtcttctac
    10921 tgcctcaaaa atgattgcct ctttcgtctc ctgtcattca tgttcactat cgatttgata
    10981 cttgcttaga ccgttgggtt tgtgaatcac caattaaaaa tggcactgag ttatggtaac
    11041 aaaaaatggt cacttgacga ggctgagatt cctacttatg aagacacatg gcacttaaga
    11101 gtcgaggtaa aggaagaagc tgaaaatata ggaggctgta cattatttgg caaaggattc
    11161 ggaaattatg atcaagacat caaaatcaaa atgttttaca gctaaatagg aagaataata
    11221 acatttcata cgctgttccc atctttaatg gcttatagag ggcaccttta gctgagaata
    11281 agacaaaaca gaccctctag cttcaattaa gagctagagg gtctgttttt gattttaaaa
    11341 cttggtttat ttcttcaaat ggtagctata ggtgctgaca acgatatttt cacgccaaga
    11401 caatcgcaat cttaaccgca aacttgtttg gttatggaga atattctgcc agcgtctgtt
    11461 tggtacaaat tgaggaatca acacagtagt tgtatagttt tgtttcgctg catttttact
    11521 tacgatatct acataacgga taattggatt ttcaatcgag cgataagaag agtggacgat
    11581 tgaaaaacgg acatctggga aatgcttttt aaattctgct tcgatttctt tttctttttc
    11641 gacatcttcg tctagcgaaa catgcatcgc aacgacataa tcaccgatcg aacgtgcgta
    11701 attcaacgca ccgatattta cccgtgtcac attcccgact aatacaagaa cggtattccc
    11761 gtcataatca tgtagttttg catcattttc taaacgaagc tgttctgcta cttttttata
    11821 atgatcatgg atcttataaa aaatgaacat aacgattggc ataatgatga agaaaggcca
    11881 aatgtcccct aaccgataga caaacaaaat cgcaatgatt gcatatgaga tgaacgcacc
    11941 cgtaatattg gcaatcgatt tgcttaacca tctttttcct tcttttttcc atttgacgac
    12001 catccctgtt tgagataaag caaatggaat gaacacgccg atagagtata acggaatcaa
    12061 gcgttctgtt gagccatgga aaataaacag caatacgatc gaacctagcg ctagtgtgat
    12121 aatcccattg gaatagccta gtcgatcccc acgatcttga tacatgtgag gcatgaattt
    12181 atcttttgcc agattgtatg caagaactgg aaaagcagaa aaaccggtgt tagcagcaac
    12241 tgctaaaatc agcgctgtag caaattgaag gacgtaatac aaaataccat gtccaaagac
    12301 agctttacca atttgagaca aaacagtgac ttctttttca ggaacgatcc cataccaata
    12361 gttgataaat gtgatcccca cgaagaagaa acctaagatc aatgccatca tcgtcaatgt
    12421 agcagcggca ttttttgctc ttggcttctt aaagaatggt acagcattac taatcgcctc
    12481 caccccagtt aaagaggaag aaccagaaga aaatgctcgt aaaatcaaag cgatagaaac
    12541 acccggcaca gccgctcctg gaagtgcagt agcttgcaat ggcacagcac ctgtcacgat
    12601 attatataaa ccaacaacga tcagtaacga gatcacaagg ataaatgtgt acaccggaaa
    12661 taataggaac gatgcagatt ccctcagccc acgaagattc agcatcatca gtagcaaaac
    12721 gattgtcaca gaaatagcga cttgatgacc gtagagtgct ggcaccgctg atgtgatcgc
    12781 ttcagcacct gctgagacag atactgctac tgtcaacatg tagtcgatca ataaagagcc
    12841 accggaaatc aagccagcat tctttccaag attctcactg ctgacgacat atgctccccc
    12901 gccatgagga taagcatgga tgatttgacg atatgatagc gttaatgaaa tcaataaaat
    12961 aataacaaaa gcggcaatgg gtagcgaata ccagatggct gcagcagaca aagcgactaa
    13021 aacgacaacg atttgttccg taccatatgc aatagatgat aacgcatcag acgacaataa
    13081 tgccaaagca gcaaatcggg ttaatttgtg ctcatcattt tcagcagatt ttaaaggctt
    13141 acctactaac aaccttttta agtaatccaa tttctaaact cctttacaca caattttact
    13201 tcaagtttta tagtcgaaaa tttatagtaa acaagatgtt atagtacgct cactgacctt
    13261 aaaagtcaat aaactttaag aaaataattg gaaaaaaaca gaaaaatatc aagcgctttt
    13321 tcaaacgctt taatacagca aaaatctaac atttttttat gggctttttc tttgaattct
    13381 ataataaaag gatagaactt gacttagaaa atcaagttct atcctttttg atatcttaac
    13441 ttttggaaga gagatgtaag gctgctttct acccatcatt cttactactc gaagcatagc
    13501 gcagttgtca caacctcttg ataaacggtg tttaaaagct tgcatctgcg gtaataagcc
    13561 caaccaaatt aaaaacataa gaagctgttt ttatttggtc gttcttatta cttgatgcag
    13621 agcagctttt ttacaacctc ttggtacacg gtgttcaatc agctgaccct cggtattagc
    13681 tcaaaaaaac ggcaaaatat gaggaactat ttttccattt ttttctctaa tactcaggtc
    13741 aaaacactga tttcacaacc tcttttttta atgaaaaata tggctctcat gcgccgcttc
    13801 tttgaatttc gtcatttttt cttcgatgaa cggatagatt gccgttccta cgattccaaa
    13861 gacaacaaac aaaccgatca tgatccagat tgctttcgta gcatttggcc aataaattcc
    13921 tcctgcagat tcccgtaaca agtttaccgc atgagtaaat ggcaagaacg gattgatcat
    13981 ttggaagaat ttccctgaga cttggatcgg atagttcccg cctccgccag agatcgacag
    14041 tactaagatg ataatagcga tccctttacc gacattatcg aataatgcag ccaagacata
    14101 gacgatcatc atgaacgcta aggcgatcaa gacagcaaat gacacgctgt agaccggatt
    14161 ttggacatct actcctagta agaaaatatt ccctaatgta acgatcaagc tttgcgcaat
    14221 cgccattgtc aaaaatgtca gcatacgagc aacgaattgt tctcgtttcg taaaattgtt
    14281 tcggtctttc tttcctaaat agtattctgt cgtagcaaca cttgaaagaa gaacagcgcc
    14341 gacccacaga catagtgcag tataaaacgg ggtgctagct gaaccgttat ttgcgattgg
    14401 ataaagcgca ttggtttgta gctcaacagg ttgtgtaaag aagtcacttt cttttgttgc
    14461 gtctagtttc aataatttga tgacttcgcc tagatcgact tcttgttcgc cttttcggat
    14521 cgcgtctgct gctttttgga taccagcttt gatatttggc cagtcattgt tgatcaagtc
    14581 cgcagcagcg ttcacagctg tttcgacttc tggcattttt tcatttactg ttgtcaatgt
    14641 accggtgatt tcatttttta gtgctggcca atcattttgg ataaaatcag cggccaatcc
    14701 taatttttgc tgaatgatcg gtaattcatt gttgtatagg tctgcccctt cattgatgcc
    14761 attgacgatg gtatccatat ttccattcag cattgtattg gcatcatgga tttcttgtcc
    14821 aattgcaggc atttcttttt gatatttttc taaaattgcc actgcattcg ttacagttgc
    14881 tttcgttgag ctgagaagcg aatcaaagtc gatctggtcc gctttgctca gtgcgccttg
    14941 tgcagtccca atcgtatcga tgacttggtc tagtagagaa gtgacagtgg aactgatttg
    15001 acctgtattg ataccagcaa tgatgccatt gatattatta acaacggcat caatttgatc
    15061 tagcaattca tcaatagcct tcgtgtcttc attttgaaca gctgtgttca aagcagatag
    15121 gcggttttgc agattgctta gcaagggttt taattgattt agctgatcaa taattggctg
    15181 taatttcgta tttccagcac ttgtttgcaa tttagtcagg aactcgacca gtttatcgat
    15241 tgcattttgt tgttgagata ttccgtcaat aaagccgttc aatacattgc tgatgttttt
    15301 cttttcatca tcagtcagct taccatcttc aatagctgtt cttacagtat ctattaacga
    15361 acctgtcgtt gttgccactt gtccaattga cttcaatgta acatctacac tgtttgtgat
    15421 gcttggtatc gcatctttca gctgagaggc acctgatttt gtttggtttg ctagatcact
    15481 tgcctgattt tctaaatttt tcacatctgg caagatatct tgtacttgtt ggatgatcgt
    15541 caagccttgt tttgcttcat cgattccttg gttcattgtc tcttggatcg aagcaaaatc
    15601 gccgtcgatc tctgctagtt gcttaccggc attttggatc tctgggattt tttcttgcaa
    15661 atcaaggatg atttttgctt gatctttcaa ctcaggcatt ttgtcattca atgcaacgac
    15721 tttttcaccc atctcatcta ctttagggat gtaatccacg aattcatttg ctttattcag
    15781 tttttccttg atttcaggta gttgactttg taattcgagg acttgttttg tgtagccgtc
    15841 gatcgtgtcc aaattttcat ctgttgataa aatcatatct ttaactttat tgatacttac
    15901 taggttcgta tcgatgtcgt aacctatctc attgaatact ttcaataaag tcgaactggc
    15961 tgttttgata aattcatttg tgatttgcga ttggatcgaa cttgctcctt tatcggtgat
    16021 tttcggtgca atcgcattga ttttttcatt taccgtatat tcgatttttg gtttcttgat
    16081 atcaccacta gtaaaactca gcagatcttc tgagaaatcc tttggcaagt aaatacctgc
    16141 gtaatacttt ccggaacgga ctccgtcttc taattgttct tttgaatcaa cgaattgcca
    16201 tcctaattgt ttatttttat gaagcgattc gatgacttgc tccccaatgg ccacttcttt
    16261 accttgaaac tctgctggct tgtctgcact gtaaacagca attggcagct ctccagtatt
    16321 tccatatgga tcccataatg ctttgatgtt aaaccacgca tatagcgaag ggatgatcat
    16381 gatcgcgatg atcagaagtg ttgcaatcgg gtttttgaaa atccgtttcc agtcaagcaa
    16441 atataatcga agcgtatttt tgattgactg catagttctc ccccttcttc ttttttcagc
    16501 tgaattactt taccatgtat ttcatacttt tttcaatcgg cttttttcaa aaaagtcgaa
    16561 tttttggaca tatcacggca attgtctcat tgtaatctct tacatattga gaaataatta
    16621 aggattacag cctttacttt atcatgaaat aaaagggaaa gataatttta tgccaaagtt
    16681 tttatctatt atacgtatac gcaaaaaagc taaaacattt tttgtctttg cccctacaaa
    16741 aatgtttcag cttttttcgt tttttattcc tgtatttctt atttttcgaa tgacaggatg
    16801 attttcccag caggaggatg tccttcaact agctgatgtg cttggatgac atgcttaagt
    16861 gaagcagaca gattcattga aataaaaaca tgaaaggctc ctttttggta ggctttgatt
    16921 atgccagcaa aggcttctgc atctagatat tcctttcttg gaacaaacga ttcataaaag
    16981 ccttcctttt tttgccgcaa atctagatct gggaggtcat ttaatgcaac atacctgccg
    17041 cctggtttca tgatctggat gccggtttct cctttgatac ttcctttcgt cgcatcgatt
    17101 acaaggtctg cctgatcagc aaattgcaga cctggatttg ttttatcata agcagcaaat
    17161 gctgaagctc ctaatttttt taccttttcc tcatttttac tggatgcact ggttaagatt
    17221 cggattccct tttcatggag aagctggatc agacttgacc cgaccgcacc tgatgctcct
    17281 agtatcatta cagtatctgt cggctggatt tccgtcaaat ggttgattag attataagcc
    17341 gtaattcctg gcgtgaccat tccggctgct tcttcccaac tcattttatc tggaattttt
    17401 gctacttttg ctgatggcaa cacgacttct tctccgtaag tcccgccgac tgcatggaca
    17461 gctactcgat cacctacatg aacagttgtg acatctgaac caatctctgt cacaatacca
    17521 gcgccatcat tacctggtac ataagggaat ttcaatgttc gtatctcttt catttctcct
    17581 aaacgcaagg caacatcata aggattcaca ctgaatgctt ttatttctac acgaacatgt
    17641 ccagaaccga cttctctggg atgagcatcg atttcttcaa aaacatcttg tgcttctccg
    17701 taaccgttaa ttgcaaatct tcgcatggtc accatctccc tttttcttta agtttacgtt
    17761 tatgccttta ttttgacaaa aaaaatgtct tttcgttttg gcgcatgatt caaaacaaaa
    17821 tagttgtctt ttttcgcgta acgtgttaaa ttatttatct aaaagcgtaa agattacgat
    17881 ttacgctaat aaaaaataat tggaggaatt tgttgatggc taaaaaatca aagattgcca
    17941 aagcaaaaaa acagcaagaa acgattgaac gctatgctgc tttacgccag gaattaaaag
    18001 cgcaaaaaga ttacgaaggc ttgcgtaaac ttcctttaga tgctcgtcca gaacgattga
    18061 aaaatcgtga tttaatcgat ggacgccctc gcggatacat gcgtaaattc gggatgtccc
    18121 gtataaaatt ccgtgaatta gcacataaag gtttgattcc aggagtaaaa aaagccagct
    18181 ggtaatccaa gtctggctgt aatgtaaagg aggagggcgc atggaccact ccttggatca
    18241 tcaaaaaaga tacgttcgct tcttctagca gaaatgctgg tactagaagc agacgtatct
    18301 ttttttacgc acagctggtc cttttttata tgtaaaggct gcatggttac ttcgctatat
    18361 ttatttagta acaggagtca gtgcttcgat acccacacta attttcaatg ctcggtcaac
    18421 ttctgccata atgggtcgat ccaaatggca gaccttttct ttcaatcttg atttatcgat
    18481 cgttctgatc tgctccaaca ggataacgga gtctctttct attcctgttc cagtagcttt
    18541 gatcccaatg tgagtcggaa gcttaggttt agccattttt gccgttatgg ccgcaacaat
    18601 gatcgtcggg ctaaaatggt tacctagatt attttgaata accaaaactg ggcgtgttcc
    18661 gccttgctcc gatcccacga ctggagaaag atcagcaaaa taaatatctc ctctttttac
    18721 cataggatcc tccttattct tgatattctc ttggtatccg ctgtcctaat ccgcaagcca
    18781 cttcatagtg gatcgtacct aattgatctg ctatatcctg catagtgatt tctttgtctg
    18841 catttttgcc gataagcgtc acttttgttc cgacaggaaa ttcttgaggc aatcggatca
    18901 tcagttgatc catacataca cgcccaatcg tttcacagta gttcccttct accaatagag
    18961 aaaaaccctg catctttcgt ggccagccat ctgcataacc gatcggtatc gttccgatcc
    19021 actctgcttc aggagtgata tatgtttctc catagccgat tccttcacct gctgggagtt
    19081 ttttgacttg aatcaattca gaaaccagct caagtgctgg ctgcaatgga taaacttccg
    19141 gtagtgcgtg cccagaggga ttaagtccgt acattgctac tccataacga atcatattgc
    19201 cgattgtttc atcatgccat aaagccgttg cactattgct gacatgtaca tatcgaggaa
    19261 gttcgggaag ttttttcagc acttctataa agcgttcttt ttgcagattc caatatgtat
    19321 catctgcctg atctgctgta gaaaaatggg taaataaacc ttcccattct aatacacgac
    19381 tttctttgat gaatgcagct gcctctttta cttcttcagg tgtacaaaat ccgatacgac
    19441 ccatcccagt gtctgctttt agatgaatcg aaagaggcgt ctctagctta cttttctcta
    19501 aaacagcagc tgctgcttgc aaccattccc gtgtacctgc agttactgat aaatcatgag
    19561 caacagctac agtcagtgcg tcgtaaggaa ccatattcaa gataaggatg ggctgagtaa
    19621 atccagcttc tctcaactcg actccttcat ctaaatttga aacacaaaag cccgaagctc
    19681 cacctgcaac tgctgcctca gctgtttcaa tagctccatg accgtatccg ttcgctttta
    19741 ctactgcaaa caattctttt ccttgcggaa gtcttgcaac ttcatttgct acattttcag
    19801 ttatagcttt tttatgtatc actgctttcg ttgggcggtg ccaagcgaca accatcgttt
    19861 ttccttcttt ctagtcttcc aaaataattt gtgcaaaagc tgtttcattt gtatgagtaa
    19921 tactgaccca tacattgcct tcatgaggtg aacgcgtcac aacaggctga ccattttcat
    19981 tttttaaaat ctcgacatct tgaaaggtaa cttttccgat cccagttccc caagctttag
    20041 agaaagcctc tttgcaagcg taacgcccgc ctaaaaattc tacttggcga tgaaaaggca
    20101 aggactggaa tagtttcatt tcatcagagg tcaagattcg tgcaatgaat tttggttttt
    20161 cttcgatcag ccgagtgatc ctaggaagtt cgactgcatc gatcccaatt ccttttatca
    20221 tatgcttttc tcttttcaat aaatttagaa cactctcatt ctaccaaatt ataaccattt
    20281 tgccacaaat aagtccacaa ataacaaaaa tgaaagtttc tcttaaaaaa gagaaacttt
    20341 cattttatgt ttaatcgtta tttgaacgga ttacaaatcc gcgtttttta tcattgtgac
    20401 gtttaccgcc atctttttgg ctgttattat ttttgctata accgcctttt gatttgtttc
    20461 cacgataatt accgccgtca cgacgattac ggttgtttcc gccaccacgt ttgccatttt
    20521 tattgtatcc ttttttctgc attggcaatg ggcgttctgg tgtgatcttc actggcactg
    20581 catcagctgg atcttttgct gtcgttttta gcaaaagtgc aactaaatct tgtgcagaat
    20641 attcttctaa taatttatct gctgtttgca ggtatttatc tagaccattt tctgcaagtt
    20701 ttgtttcgat ttgttcaact gcagcaccta attgaccttt gaatgcttct ttttcggttg
    20761 gtggacgtaa agtcgtcatc cgttttttcg tcaagttttc aatcacatgc aagtagtcca
    20821 tttcatttgg tgtaacgaaa gtcacagaca taccgccttt tccggcacgg cctgtacgtc
    20881 cgatacggtg aacgtagctt tctggatctt gagggatatc atagttgtac acatgagtga
    20941 cacctgaaat atctaatcca cgtgcagcaa cgtctgtcgc tacaaggata tctaaatgac
    21001 cgctcttaaa tgaacgcaat acgctcattc gtttttgttg agacaaatcg ccatggattc
    21061 cttctgcacg gtaaccgcgt gcttctaatc cgcgtgccaa ttcgtctaca cggcgttttg
    21121 tacgtccgaa gacgattgtt aattcaggtg tttgaacatc aaacaagcga gtcatgatat
    21181 cgaatttttc gtattctttt gcgcggacat agtattgatc gatcaagtca gctgtcattt
    21241 ctttcgcttt gatcttcaca tgatgtggat ttttcatgaa tttaacgcca atattcttga
    21301 tagctggcgg catcgttgct gagaaaagta atgtttgtct ttgatcagga acttgtgaaa
    21361 tgattttttc gatatcttcc aagaagccca tattcaacat ttcatctgct tcatccaaaa
    21421 ctaatgtttg aacggttcca agtttcaatg tgtggcggtt aatgtggtca agcatacgtc
    21481 ctggtgtacc cacaacgata tgtggacgat ctttcaagcc acggatctga cggccaatat
    21541 ctgctccgcc gtaaacggct tgtacacgta cttttttgtc gcgccctaaa cgatataatt
    21601 cttcttgtgt ttggatagct aattcacgtg ttggtgcgat aactaaacct tgtaattcgt
    21661 gacgatctgg atcgattttt tctaacattg gtaatccaaa tgcagctgtt ttccctgtac
    21721 ctgtctgtgc ttgtccaata acgtcttttc cagctaatgc tagtggaatc gtttctgctt
    21781 ggataggcgt tgcttcttca aaaccagcgc gttcgactga tttcaacaat tctggtgata
    21841 attctagttc tttaaatttc aaatgaatcc tcctatatgg ttgttaactg aggatgtagc
    21901 ttttttgcta ccccgtcgat ttgttcggtc aaagtgtatt gtttcttttt gacagtggcc
    21961 acgcacgttt ttatccattc ttagcccctg tggcaccacc gaaaaatcac tttgcgaagt
    22021 ttaggcatta gaaaagccaa acgggtcgcg ttcagcttta tcattattat gacatctggc
    22081 ttcaacaagt tgtttctatg gcaaaaccag tccaatttct cttcatcttt cggcaatagg
    22141 ttattctaac atagtttttc gttttctgca agtttacaga tttttatttc atttgctgaa
    22201 gttgttctac cacttcaaat aagcccatgc tgttgctgcc ttttagcata atactatctg
    22261 ttgcttcaag attttgtttg atagcatcaa tcaatttatt cttttctttt tcaaaataga
    22321 acacaggtag ttgggggtat ttttggttca attcttcttt tagtgcatgc atttgttccc
    22381 cataaaggaa aatcatggcg aatttctcag gatcgatatg ttcactcatt tgcgcatgca
    22441 tatttaaaga ctctttccct aattccagca tatctgctaa cacagcgatt ctgcgtcctt
    22501 ttgttggcag atttttaaaa gtatctaata ccagtcccat ggctgttgga tttgcattgt
    22561 agacatcgct caaaatagct gcaccatttc ctgccgttag ccattcggtt ctgttttgag
    22621 tgatagaaac atgggcgagc ccttggcgta tctcaggtat ggacagtcca aagaagcgcc
    22681 cgatcgtata cgcaatcaaa gcattcgtta cattataact tccaggcagc gggatcgtaa
    22741 atgtttctcc ttctactaca aaatcggttt gtgcttttcc ttttgctgtc acttccgcat
    22801 gaacatcgcc atttccaata ccgaatgttg tgactgtttg tactaatgtt gccgttaaag
    22861 gtgtcagcaa cggttcatct gcgggcacaa cgagtaatcc gtctgataca agtccgtcag
    22921 tgatttccat tttggcttta gcgattcctt ctcgcgaccc aagattttct atgtgtgctt
    22981 caccgatcat tgtgattgct gcagcttttg gttgagccat aagtgaaagt tccgtgattt
    23041 cattggcgtg atccatgccc atttccaaaa cgatcttttc tgtatcttgg ggcatgtgca
    23101 aaatcgtgta aggaagacca atattattgt tgtaatttcc ttgcgtctta tatgttttgt
    23161 atttttcaga caagacagac gcggttagat ctttcgtggt ggttttacca ttgcttcctg
    23221 taattgcaac gacttctgcg cctacttttt ccaagtaata ggttgccaat tgctgcatgg
    23281 ctttcaaagg atctgctaca ggaataactg gaaaattttt tggagcttgt tcaacaggca
    23341 agctccaaaa tgaagcagat gctccgtttg tgatcgcttg ctggataaat tcatgtccat
    23401 ctcgcgtacc agcaagagga acgaataaac ttccttcggt tatcttccgg ctgtcaaatt
    23461 cgacattggt aatctttgtc agtgcagagc attcgctgcc cacggcttgt gcaatttctt
    23521 gtattgttag attcattgag atctctccta aaaaaggttg tgaaaaaagc gtttggccta
    23581 aacggcgggt tcgcatgact ctcacttcca agtaaatttc tctattcgta tttagaagct
    23641 agaatgaacg cggttacgca atcactccag cctcttcttt atttctcttt attcattttt
    23701 ttcaaaaaaa gattgacgct gatggtatcg attcattcct aactggatca gttcttcaat
    23761 caaatcaccg tatttcaagc ccatattttc ccataagagt gggtacatac tgaactccgt
    23821 aaatcctggc atagagttta attcattcag gaataattca tttttatttg tcaaaaagaa
    23881 atcgcaccgg ctcaatccgc ttccacctaa catcgtgtaa gctaacttcg cgtactcttg
    23941 cgctttttga taaacttctt ctggcacttc ggctggaatc tgcatttcga ttttattatt
    24001 gatatatttt gcttcataat catagaatgc tacgtctttt acgacttcac caggcaaagt
    24061 cgtccgaacg tcttcatttc ctaatacagc aacttcgatt tcgcgcgctt caattccttg
    24121 ttcaacgatt gctcgagaat catactgata ggctgttgct aaagcatttt gcagctcttc
    24181 tcggttttct gcttttgtaa tgccgacact agaacccata ttcgccggtt tgacaaacat
    24241 cggataaagc aaagaacctt cacattgatc aaatactttt ttaggatttt ctttccattg
    24301 attcttaagt actggtacat aaggaacttg cggcacacca gcagcttgta aaatatactt
    24361 ggtcatgatt ttatccatgg cacatgcact ggtcaatacg cctgcgccga cataaggcat
    24421 attcaatgtc tctaagaagc cttggatcgt tccatcttcc ccgtttggcc catgtaaaac
    24481 tggaaaaacg atggctcctt cttctttgat ttcgcccgga ttgatcactt ttcctgtaaa
    24541 gccttcctct gtctgtccac ttgggtccca tgaaagatgc aagacatctt tgctggcagg
    24601 tttttctgtt agtaatggac ctttgaccca ttgtccttct tttgtaataa atacgagttg
    24661 aacttggtaa taattataat aaatggcatt taaaactgaa aatgcggaaa gaatggacac
    24721 ttcatgctct gcgctgcgtc cgccatatag taaagtaatc ttcaaaagat tgtcctcctg
    24781 tattctaaat cgttcagtga tttactctca tattttagca caaaacaaaa ataaacgaat
    24841 aacttattta taaaaaaacg agccagcttc taaaagaacg agcgtcattt attttttgtc
    24901 agctagatta tttgtcccgt tttttataaa aagttatgat aaagaaaagg agggatgatg
    24961 atggcgcaaa caaatccacg cagccgcttg gcagaaatca ttcgagtgtt catcaattac
    25021 aatgtagtgc caaactttgt acagcaaaaa aatcccgaac aggtaaaaaa agcctttgaa
    25081 gaactaggcc ccaccttcat caagatagga cagatgcttt ctgttcgaga agatttgctt
    25141 tcttctgcct tcactcaaac attcaaaaca ttacaagata gtgtacctag cgacacattt
    25201 tcaacggtca aaaagacgat cgaaacagaa ctttctcttt cattatcaga tatattcgat
    25261 gatttttcaa aatcgccttt tgcctctgct tctatggggc aggctcatcg tgccaagctg
    25321 aagaacggtg acgcggtagt cgttaagatc caacacccta acatcgccga agagatccga
    25381 cttgatcttc aactatttga acgagcgatc cctttgatca aatacattcc tgaaactagc
    25441 gtagttgatc taaaaggggt actccaagaa gtaaaacgtt ccttgatcaa tgaaatggac
    25501 ttcttaaaag aaagtcaaaa tggcgaacaa ttctatcaaa agaacaatgg ctggaaagag
    25561 atccgcagcc ccaagattta tgacgctttt tgttcgaaaa aagtgatcgt gatggaagaa
    25621 atgtctggta aaaacttgaa tcatttaatg aacgccgaaa acaaaactga aacttttatc
    25681 actggaattc aaaacaagca gctgaaacaa gaagttgcaa agcttttagt tgagaacttt
    25741 atgaaacagg tgtttgatga tggttttttc catgctgatc ctcatccagg gaatctgcta
    25801 ttccatgtac taacaaaaga agaacagaca caagctagcc gaaaaactga aacagtccat
    25861 gaaaaagagt tcggttcctt tgcttttcga gcctccactt ctgcagaaga ccctgttgcg
    25921 ccatatacca tcaactacat cgattttggt atgatggggc atctttctgc aggacttagg
    25981 caaaaactca cacaagccgt tttagcgctg tatacgaaag atgcttatcg aatcgaaaaa
    26041 gcggtccttc gactttgtca gcaagaaggc tcgtttgatg aaagtcggtt ccaccaagaa
    26101 ctgacaagtt ttcttgaaca gtattatgat tctcctattg atgaaatcaa cttgcaagaa
    26161 gtattcacac atgtcgtgac gatttgtcat caaaataatc tgcagttcga tcgtgatatc
    26221 acgcttttgc tgaaagcatt tgggacatta gaaggggtga tccgcgtcct cgatcctgaa
    26281 gtttccctca tggaagtcgc ttcgcctttt gctcaacatt attttctcac tcatctggat
    26341 gtagaagata cattgaaaca aagcggatta gacttattgg aagggatgaa ggctgcgcct
    26401 aagatccctc aacagctcca ccatctatta gaaatgtgga cttcgggaca aggaaaagtc
    26461 aatttggaat tgaaaaagca agacaaatta ttgagcagga tcgaaagtat gatcaatcgg
    26521 cttgttttcg gtatgatttt agctgcattg atcgtagggt cctccctgct tgtccaagca
    26581 gcacctgtag aaaacgcaga ggtcgtttcc ttattaggga tatttacgta tgctattgcc
    26641 gcattcgtca ttattttttt ggcaatcgat gcattgatcc aaatgtataa gaagaggaaa
    26701 aagtagaaaa aggttgtgac agaaagaatc agcttcaaga aataagaagg ggttttacat
    26761 aaattgtttc tcaaattttt gtgaaaattc ggcttatttt tcgaagaggc tacttctgaa
    26821 acaccgagaa taaaaaatgt gaaaaagctg ttctgcaccc agtaataaga acaatcaaaa
    26881 agggaacatg gaacacattt atcctgtttc cctgttccct ttttgatgta ttcgagcata
    26941 aataaaatac cttcgttacc tactatcttc tgtacttggt aaaccttagt caattgcctt
    27001 ttttaacgct tgacgaaaag acatatgatc tttctccgta aagggttttg gaccctttgt
    27061 ccttatgcca gcttttctta actttccact atgataacgt tgttctagaa gcgtgccgat
    27121 attcgcttcg tcaaattctt ttccagagtg atggaacact cgcacaccct tcggcaatac
    27181 aagtgaagct aaaccataat cttgcgtgat caaaaagtca ttcttcttaa ccataccgac
    27241 gattttataa tccgcactat cagctccgcg gtctacgtag acgatttgga catgattagc
    27301 gtattctttg gtcgtataat ggtccacact ggtcacgata accacgtcaa gaccatagga
    27361 ttctcctaat tttatgacat cttcttttac tggagaacca tctccatcaa tgaatagcct
    27421 cattcttttt cgccttcttc cataaatgat aaacagttac taatccgctc agtaaaagac
    27481 caacattgat ccattttgcc aagataagca gttgtacact ttctatcggc actgattcat
    27541 ggttcagcgt gatcaataat agatggattg gctctcccat ttcttttgct aaaacaaaca
    27601 aaagcgtcat caataaaaac tggtggatca cactcccttt attttgagta gtatacttga
    27661 caacgatccg gcgatccatt ggaatagctg tatcagtttg ataatattcc ttatttagcc
    27721 agctgcctgt tactacgtgc cagaaactaa gcagaaagac acctatcgca aaaccatttg
    27781 gaatcaagag gaccaataaa gaagaactca gtccaagcaa ttgcatagcc aatggagacc
    27841 atgttaaacg tttcaaaatc catggtccga ctatttttgc tgcaatcaag cctgctgcat
    27901 aaggcaaata cataaaaatc gaaagttttt ctaatccgta cagtatgcca acataaaaac
    27961 tgctaaataa aaaaaggaaa ttccctagca ttccatttag aaaagtaaac agatttagcc
    28021 agcttggcaa cttccattcc ttcttctggt gtcctaaaac aaacacgaac aagatgaaca
    28081 gcagcaagaa accataaata gcaagatcaa aaagcctttc atcgaataac aatcgggcat
    28141 ttctcaaaag aaacaataag ccaaagaata tcaaaaataa aacaagctct cgcgtagcta
    28201 ccagatttct tttgatgtct ttgaaatcca gttcgtaacg cggataatga ctaaccgtat
    28261 ggtaggccat gacgtaaaaa agtgtataaa tagtaaagct tgctgcaatc tgagtcggtg
    28321 caggcaactc aatcgcttga tacaggagaa atagccagat agctgcaaat aagtactttt
    28381 tcccatccat attgataaaa ccttgcgtct tttcgtgaaa attgaccgtg gtattagcag
    28441 gtacaagcca tgctgcactc agccctagca aaacacttga aaaataaaat aaaggaaaat
    28501 aaaatacgcc taatattcca agcaatgaac cagcaccacc aatcagcaga gcgatcatca
    28561 gcaacgtgta actatctaga ccaaatcgta gactgttgac taaaaatagt ccagtcatcc
    28621 gaaaggcata aaacagcgta aatggcaaaa tcgtcagcca attatgcgag tctgttagtc
    28681 ccaaaaataa aagataagga ataaaaataa ccgtgttact taagataaag ggcgttgttt
    28741 gtgtaaaatt acgcccaaat cgtttgagtt tttcgaacat gacaatggct ccttaaacag
    28801 tcttataact aatctgctct tcgattttag cattaaaggg gaaataaacc aattttacag
    28861 aatatattct tgtaaaaaaa aatacagaaa gaagcataag cttctttctg catttttacg
    28921 gtacttgatt actcaagcag acaagccctt ctccacaaaa gtcttgcccg acacccctgc
    28981 atccggcagg tgataaagat agaaatcaat tatcctgtgc ctccaaaatc aattaggagc
    29041 tctgtaaacc agagtccttc tcgacccgtc gcataaattt actttaacac agttcctatg
    29101 tttatgcgag agcttttttc attttataat cgaccatttg aaatccttga ccgatatctg
    29161 aaataagttc ttctgtaatc tcaaatcctt catgcttata aacctcgatt gcttgatgat
    29221 tcccctgatt cactcgcaaa aagatctctc tttcctttgt ttgcgcagca agttcttcat
    29281 accagcgaaa aactgaagaa gtcaatcctt gaccacgtac tttatttagc aaatataatt
    29341 tacttaaata aatttttcca tttatctctt cataagcagt gtaaccgaca gtcttttctt
    29401 cgctttttaa taaaaagtag gacacacctt ctgtcagttc tttttgaatc tgtttttttg
    29461 actgataagt tttcagcatg taatccactt gtttttgacc aatgatcggc acaaaaactt
    29521 ccggccatac ttcttgtatg actgccatca gctcatccag ttcattttct gttactttta
    29581 ttttttccat acacccacgt ccttttttac attataaatg accttgcgct tgatggaata
    29641 aaaagagcat gatcatgcta tacacaccca ccgaccacgg tttcaagaaa atcacaatct
    29701 gcataaattc cctaaaagat aatttcgtca aaccagctac tagacagatc aagtcgtctg
    29761 gcgcaaaggg aagcagcaag gtaacaacta gtactttttt aatatctttc gtttttcttg
    29821 tcagcaattc atcaaatttc tgatactttt ttggcgataa aataagctgg acaaaggcta
    29881 cgccatagta acggacaagc aaaaatccga ttgcttcccc aatcactagg ccaatacaac
    29941 tatataaaag cccaaatcca ttgccaaaca tcagcatgcc cgctactgag gagatccctc
    30001 ccggcaaaat aggaatgatc acttggatca cttgcaacag aacaaatatc atcactgcat
    30061 acttgccaaa ttgctggata aacgcttgca aagacgtgct cgatcgaaaa atcccatgat
    30121 gataagcata aagaatcaac acaaagaaaa aaaacagacc aataatgggc atgatctgaa
    30181 gacatttttg taaaactgat ccttttttag acatctatat tccccacatc ttttttcatt
    30241 tattaaaact gcctcct
//
LOCUS       DADVXV010000027        30055 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.027, whole genome shotgun sequence.
ACCESSION   DADVXV010000027 DADVXV010000000
VERSION     DADVXV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.027"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(29..1261)
                     /locus_tag="KB969_001151"
     CDS             complement(29..1261)
                     /locus_tag="KB969_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBB6869153.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="KB969_001152"
     CDS             1516..2085
                     /locus_tag="KB969_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6869154.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="KB969_001153"
     CDS             complement(2263..2703)
                     /locus_tag="KB969_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBB6869155.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="KB969_001154"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="KB969_001154"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBB6869156.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="KB969_001155"
     CDS             3657..4580
                     /locus_tag="KB969_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBB6869157.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="KB969_001156"
     CDS             complement(4805..5044)
                     /locus_tag="KB969_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869158.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="KB969_001157"
     CDS             complement(5049..5468)
                     /locus_tag="KB969_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6869159.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /locus_tag="KB969_001158"
     CDS             complement(5695..6933)
                     /locus_tag="KB969_001158"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6869160.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="KB969_001159"
     CDS             complement(7040..7675)
                     /locus_tag="KB969_001159"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6869161.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8017..8652)
                     /locus_tag="KB969_001160"
     CDS             complement(8017..8652)
                     /locus_tag="KB969_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6869162.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="KB969_001161"
     CDS             9164..10306
                     /locus_tag="KB969_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBB6869163.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="KB969_001162"
     CDS             10299..10505
                     /locus_tag="KB969_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBB6869164.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="KB969_001163"
     CDS             10584..11777
                     /locus_tag="KB969_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6869165.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11982..13121
                     /locus_tag="KB969_001164"
     CDS             11982..13121
                     /locus_tag="KB969_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBB6869166.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="KB969_001165"
     CDS             13114..13914
                     /locus_tag="KB969_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6869167.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="KB969_001166"
     CDS             13914..14741
                     /locus_tag="KB969_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6869168.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14719..15453
                     /locus_tag="KB969_001167"
     CDS             14719..15453
                     /locus_tag="KB969_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6869169.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="KB969_001168"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="KB969_001168"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBB6869170.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="KB969_001169"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="KB969_001169"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBB6869171.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="KB969_001170"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="KB969_001170"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBB6869172.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="KB969_001171"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="KB969_001171"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBB6869173.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="KB969_001172"
     CDS             19038..21071
                     /locus_tag="KB969_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869174.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="KB969_001173"
     CDS             21115..22395
                     /locus_tag="KB969_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBB6869175.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22605..23411
                     /locus_tag="KB969_001174"
     CDS             22605..23411
                     /locus_tag="KB969_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869176.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23423..24643
                     /locus_tag="KB969_001175"
     CDS             23423..24643
                     /locus_tag="KB969_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869177.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24633..26219
                     /locus_tag="KB969_001176"
     CDS             24633..26219
                     /locus_tag="KB969_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6869178.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26258..28396
                     /locus_tag="KB969_001177"
     CDS             26258..28396
                     /locus_tag="KB969_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6869179.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28764..29747)
                     /locus_tag="KB969_001178"
     CDS             complement(28764..29747)
                     /locus_tag="KB969_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBB6869180.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         9601 a         5276 c         5967 g         9211 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    22441 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    22501 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    22561 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    22621 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    22681 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    22741 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    22801 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    22861 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    22921 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    22981 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    23041 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    23101 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    23161 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    23221 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    23281 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    23341 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    23401 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    23461 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    23521 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    23581 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    23641 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    23701 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    23761 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    23821 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    23881 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    23941 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    24001 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    24061 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    24121 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    24181 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    24241 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    24301 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    24361 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    24421 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    24481 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    24541 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    24601 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    24661 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    24721 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    24781 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    24841 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    24901 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    24961 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    25021 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    25081 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    25141 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    25201 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    25261 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    25321 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    25381 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    25441 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    25501 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    25561 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    25621 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    25681 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    25741 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    25801 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    25861 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    25921 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    25981 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    26041 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    26101 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    26161 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    26221 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    26281 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    26341 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    26401 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    26461 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    26521 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    26581 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    26641 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    26701 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    26761 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    26821 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    26881 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    26941 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    27001 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    27061 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    27121 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    27181 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    27241 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    27301 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    27361 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    27421 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    27481 gtctagaaga aacatcaaag gaagcgtacg tcctggcaga atttctggat tttatgagat
    27541 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    27601 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    27661 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    27721 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    27781 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    27841 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    27901 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    27961 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    28021 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    28081 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    28141 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    28201 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    28261 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    28321 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    28381 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    28441 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    28501 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    28561 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    28621 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    28681 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    28741 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    28801 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    28861 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    28921 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    28981 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    29041 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    29101 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    29161 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    29221 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    29281 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    29341 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    29401 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    29461 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    29521 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    29581 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    29641 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    29701 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    29761 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    29821 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    29881 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    29941 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    30001 agaggtgtat aaagcttttt attagacatt tttaaattcc attacaattt gctta
//
LOCUS       DADVXV010000028        29955 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.028, whole genome shotgun sequence.
ACCESSION   DADVXV010000028 DADVXV010000000
VERSION     DADVXV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.028"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..616
                     /locus_tag="KB969_001179"
     CDS             <1..616
                     /locus_tag="KB969_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6869181.1"
                     /translation="FVFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVG
                     KYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGT
                     GVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPF
                     ILALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            613..1386
                     /locus_tag="KB969_001180"
     CDS             613..1386
                     /locus_tag="KB969_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBB6869182.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1383..1781
                     /locus_tag="KB969_001181"
     CDS             1383..1781
                     /locus_tag="KB969_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBB6869183.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1966..2637
                     /locus_tag="KB969_001182"
     CDS             1966..2637
                     /locus_tag="KB969_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869184.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2696..3136
                     /locus_tag="KB969_001183"
     CDS             2696..3136
                     /locus_tag="KB969_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869185.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3148..3816
                     /locus_tag="KB969_001184"
     CDS             3148..3816
                     /locus_tag="KB969_001184"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBB6869186.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3880..4503
                     /locus_tag="KB969_001185"
     CDS             3880..4503
                     /locus_tag="KB969_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6869187.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4559..4945
                     /locus_tag="KB969_001186"
     CDS             4559..4945
                     /locus_tag="KB969_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBB6869188.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5158..6549
                     /locus_tag="KB969_001187"
     CDS             5158..6549
                     /locus_tag="KB969_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBB6869189.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7160..7528
                     /locus_tag="KB969_001188"
     CDS             7160..7528
                     /locus_tag="KB969_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBB6869190.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7708..8649
                     /locus_tag="KB969_001189"
     CDS             7708..8649
                     /locus_tag="KB969_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBB6869191.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8718..9449
                     /locus_tag="KB969_001190"
     CDS             8718..9449
                     /locus_tag="KB969_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBB6869192.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9593..11773
                     /locus_tag="KB969_001191"
     CDS             9593..11773
                     /locus_tag="KB969_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBB6869193.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11793..12275
                     /locus_tag="KB969_001192"
     CDS             11793..12275
                     /locus_tag="KB969_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBB6869194.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12291..13052
                     /locus_tag="KB969_001193"
     CDS             12291..13052
                     /locus_tag="KB969_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6869195.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13183..14517
                     /locus_tag="KB969_001194"
     CDS             13183..14517
                     /locus_tag="KB969_001194"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBB6869196.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14824..15309
                     /locus_tag="KB969_001195"
     CDS             14824..15309
                     /locus_tag="KB969_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBB6869197.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15302..15985
                     /locus_tag="KB969_001196"
     CDS             15302..15985
                     /locus_tag="KB969_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBB6869198.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16111..18756
                     /gene="polA"
                     /locus_tag="KB969_001197"
     CDS             16111..18756
                     /gene="polA"
                     /locus_tag="KB969_001197"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBB6869199.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18801..19637
                     /gene="mutM"
                     /locus_tag="KB969_001198"
     CDS             18801..19637
                     /gene="mutM"
                     /locus_tag="KB969_001198"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBB6869200.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19601..20230
                     /locus_tag="KB969_001199"
     CDS             19601..20230
                     /locus_tag="KB969_001199"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBB6869201.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            20282..20614
                     /locus_tag="KB969_001200"
     CDS             20282..20614
                     /locus_tag="KB969_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6869202.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20926..21417
                     /gene="nrdR"
                     /locus_tag="KB969_001201"
     CDS             20926..21417
                     /gene="nrdR"
                     /locus_tag="KB969_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBB6869203.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21440..22813
                     /locus_tag="KB969_001202"
     CDS             21440..22813
                     /locus_tag="KB969_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6869204.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22813..23739
                     /gene="dnaI"
                     /locus_tag="KB969_001203"
     CDS             22813..23739
                     /gene="dnaI"
                     /locus_tag="KB969_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBB6869205.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23868..24308
                     /locus_tag="KB969_001204"
     CDS             23868..24308
                     /locus_tag="KB969_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBB6869206.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24452..25153
                     /locus_tag="KB969_001205"
     CDS             24452..25153
                     /locus_tag="KB969_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBB6869207.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25150..26271
                     /locus_tag="KB969_001206"
     CDS             25150..26271
                     /locus_tag="KB969_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBB6869208.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26286..27518
                     /gene="pepT"
                     /locus_tag="KB969_001207"
     CDS             26286..27518
                     /gene="pepT"
                     /locus_tag="KB969_001207"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBB6869209.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27650..28558
                     /locus_tag="KB969_001208"
     CDS             27650..28558
                     /locus_tag="KB969_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBB6869210.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28593..28865
                     /locus_tag="KB969_001209"
     CDS             28593..28865
                     /locus_tag="KB969_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBB6869211.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28876..29922
                     /locus_tag="KB969_001210"
     CDS             28876..29922
                     /locus_tag="KB969_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBB6869212.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
BASE COUNT         9964 a         5142 c         6584 g         8265 t
ORIGIN      
        1 gtttgttttt gcaccgttag aaggagaaga cctcgcttca tttctggttg gtgcggcaat
       61 catgatgatc ggaatgacgc tctttttgtt tggagcagat tattctatga tggaagtcgg
      121 agatctagta gggaaatata tgatcaaaaa gaaaagtttg accgttttgg tcagtttggg
      181 atttgctatc gggatcgtga tcacgattgc tgaaccttcc gtgcaagttt tgggacaaca
      241 agtatatgat atatctgacg gagagattgg cagagtgttg ctgattggga tcgtcagcgt
      301 cggcactgga gtatttctag cctttgcgct gcttcgggtc gtattcaagc tatcctatta
      361 tcaattgatg gctataggct acataggcgt tttgatcgcc tcatttttca ccagttccga
      421 atttatgccg attgcttttg attcgggggg agtgactact ggtccagtaa ctgttccatt
      481 tatcttggcc cttgccggag ggatgactag tatgatcaaa caaaagaaaa atgaaaatga
      541 cagttttgga atggtcggta ttgcttcgtt agggccgatt cttgccgtga tgattttggg
      601 ggtgatcttc caatgagttt ctggcagcaa gtgatagatg gaatcgaaat cgttaccatg
      661 gaagtcattt tggcagtggc acctatcgta atcctatttg ttttaatgaa tatcattagt
      721 tttcgtatgc gcaaaaagcg tttctttgac attatgaaag gtttcttgat aacgactatt
      781 gggttgatcc ttttcctgca cggagtcaat atggcttatg taccggtagg acagcattta
      841 ggcagtgcta ttgcgggatt gccttacaat tatatactgg ttccccttgg ctttttaatg
      901 gggttcttag tagggtttgc tgagccggcg attcatgtaa tgatcaaaca ggttgaagaa
      961 ttgagcgagg ggagaatccg atcgaaaatc atgctgatgg taatttcaat tgggatcggc
     1021 gcagcagtag gattgtctat gtggcgtttg ctcgtcggat tctctcttta ttatttcttg
     1081 atcccaggat acgggctagc atttatttta ggacgaaaag tggacaagat ctttttagca
     1141 atggcttttg ataacggtgg agtagcaacg ggcccgatgt gttcgacatt tattttatca
     1201 atgagcgtgg caatcgctgc acaaattgaa ggaagagatc cgatcattga cgggtttggt
     1261 gtggttgcaa tgattgcatt gacaccaata ttatccactt tagtactagg atatatttat
     1321 aaacgaaaag atgaaaaaga cagaatcgaa aaagaaagat tgcaaaaatt gggggaaagc
     1381 aaatgaaaga tcttgtagca ttgaatcttc acatgattgt gacgatcgtt gacggaggaa
     1441 tgggcgaaga tgttatcgac ttttcaaaag aagcaggtgc agcaggcgga acgatcttac
     1501 atggaagagg ttctggtgta catgattcag ggaaattttt aggtttggac atttcgccag
     1561 aaaaagatat tgtgttgaca ttagtacccg atagtttgac gaataaagta atggatgcga
     1621 ttggtcaagg catcaacatc gatattccag gtaatggtat ttgttttagt attgatgtag
     1681 acaaagtcat tggtatcact aagattcatc aatatcgaga aattatcgga atgcaagaac
     1741 ttttagatga aaataacgat agagaaaagt ctgaatcata gacaagcgtt tgaagaggaa
     1801 ataaacacaa acaagaaggc ggatgagcgt tatttccgct tttttgtttg tatttttctc
     1861 gtgaatactt atgaaatagt aaatttttat gaaattctac tctaagcatc agactttctt
     1921 ttcaaaatat gctattttaa aaatgatgaa aaaaggggga gaaaaatgaa ttttttagtt
     1981 gttttaaaag atactctgat tgagcgattt acatttctat atgttcaatt gcaggaaaat
     2041 aaaacattgc tgcatttttc accagagttc catctagagg ggctaacatt aggagaaatc
     2101 tatcaagcag aagggctgtc ggctgttttg cactttttta aggtagaatt ggaattacca
     2161 gtaaaagatt atatcgagct ttctcttgaa tcttgggatc gagcagtggt tgaactgttt
     2221 ccagaaggtt taatgatcga tacaaacgat gggaagatcc atctgactgc agcagaactg
     2281 caaaaacaaa tgcgttatca aatagatgac gaaaattctt tttctatttt tagacgtcag
     2341 caaaagattc taaaaagctt tttaaaagtg atcagtaaaa aacggaatct gatcaaaacg
     2401 acacagctgt tgaaaaaata tccaggtctg cttcacacgt ctattcaatt tcctcaattg
     2461 attacgatga tccatcgttt tatacgtatg caacagctac catctaagaa gctgtttctt
     2521 ccattgacgg acacatttcg agtagtcaac agagaagata aaaagaaagt gattgtgatt
     2581 gactttacca gaaatcggaa tgtccttcac caagttgcaa tggaaaaggc caattaaggc
     2641 tttttctttt tggatttttt tgtcataata aatattagat gatggaggag ataatatgat
     2701 gcaaacatgg ttagaaaggc taatacgatt tcagcagaac tatcacaaac ttatgcaggg
     2761 aagatatgcg aaatttgatc agttgaatcg cggtctattg atcgctgcgc ttgtctttag
     2821 tttgctaagt cgttggttgc cctatagaat cggacaattg ttgttcatcg tctttttcgg
     2881 atggatgata tttcgtttcc tatcaaaaaa aatctacccc agactaaatg agaatcaacg
     2941 ttatttgaaa tatcttgata gagtcaaaga aaaatatcat cagataaaaa acaaaaagca
     3001 agtcaaaatg gatcgaaaaa gttatacttt ttttgagtgc ccgaattgtc atcaaaagca
     3061 gcgtgcacct aaaggaaaag gacgaatacg tgtgacatgc aaaacatgtg gtataaaatt
     3121 cgaaacgaat gtttaaggga gaaaagaatg aaattagtat tattacgtca tggcgaaagc
     3181 gaagcaaatt ttgaaaatta ctggacagga tggctagatg tcgccttaac agaaaaagga
     3241 aaagaacaag cagcagttgc cggtcaaaaa atgcttgaag ccggacttca attcgatgcc
     3301 gtttatacct ctgttttgaa acgtgcgatt cttaccggac aagtcgcact agaagaaatg
     3361 ggtcagttat ggcttcctat aataaaaaca tggcgtctaa atgaacggca ttatggggat
     3421 cttgtgggta aaaacaaaga taagatgaaa gaaatatacg gaaaagatca agtaaaaaca
     3481 tggcgcagag gatatacgga agttccgccg ttaaccgcag aaaatagatt tgaccgcaga
     3541 tatgatcact tggatccgca tttgatccca tacggagaaa gtctggaaat gacagtgaat
     3601 cggatcattc ccttatggca agatcatcta gcaccaaaac taaaagatcg gcaagattta
     3661 ctagttgtgg gtcatggtaa tagcatccga gcactgacaa aatatttaga agatgttcct
     3721 gaagatcaaa tggatacgat cgatatccca aatgcacaac caatccagta tacattagca
     3781 gatgatttga caattctgga caaaaaaata ctttaaagaa cacctttatc taaaagtgag
     3841 agatagaaaa aagaagcaaa ggaatggaac aaaaggaaca tgaaaaatta tatatgggac
     3901 tttgatggta cattgtttga tacgtatccc gcaatggtag atggtgcatg gcaagcacta
     3961 aaagattttg gtatcagtat ggacaaaaaa gaaatctact tcaaaatgaa aaagtattct
     4021 actagttatt tgatcaatga atcaaacttg aatgccagag agtttaatga attatttcac
     4081 cgatatgaaa aagaaagtac ggaagtttcc cgtccatttc cagaaacgaa acaagtactg
     4141 gaaatgctaa aagacaacgg cggtcgtcat ttcatcctga cccaccgttt gacagaatca
     4201 acatggggcc tgttaaaaga acatcgattg gcacatctga ttgaggaagt agtagggatc
     4261 gatcaggact ttcctcgtaa acctgatcca gcatctttaa attatttgat cgatactttt
     4321 catttagaaa gaacagacac gatgatgatc ggcgatcgtc gtttagatat cgaagcaggg
     4381 aaaaatgcag gagtcgctac ttgtctttac gacatcgatc attttctggg tgagatcccg
     4441 gcagattatg tggtaggaaa tctgaatgaa atccttacct tgcagagcat cattaaaaag
     4501 tagtatcccc tttcaaagga gatatgttat aattttcata aaggagtgat aaaattatat
     4561 ggaaatcaga agacaaaaag aagttgtaga agcatttcat tatgatatga gattgccgaa
     4621 ccaagaagta gaaacagatt tgaaagtagg cttctcgcct ttaaaagaaa cgatcgaaaa
     4681 ctatccgaaa gaacatagca tcgtaggagc acgcttagag ttccgtttag tgtttgatac
     4741 atatgtttta tctggaagtg tgagtcagat caatcatatc ctcaatcgga aaattgaagg
     4801 tcaaaatgat gtcacacaag aagaagtgga cgagctagta gcaccgttat tcgatatcgt
     4861 acgccgaatg tcttatgagg tgacagagat cgccttagat cagcctgggg taaaattgaa
     4921 ttttcaatca gaaaaacaag aatagacagt aaaaacatac ctgcgataga ttaaagctat
     4981 cacaggtatg tttttttatt actaattgta agcaaaaaga atgtcatttc gataaaaatc
     5041 gtctaaaata taaaagtcac tgaaaaaaat tttttcagga ggatggttga agaatcattc
     5101 tcgggaacct ttacttcctt cgatggactt gtcattaata atatgaggag gagaaaaatg
     5161 acaacactca tcacagtttt agtggttcta gtttttgcgg cattattata tgtgttctat
     5221 cgtatgcaaa agcgccatac aaaattttca acacgcgtct ttacagcatt aggagttggt
     5281 atcgtctttg gcggtctgct tcaattgatc tttggtgtag acgacaaagt cgttactcaa
     5341 tcaatggaat ggatcgggat tgtaggtcaa ggatatgtat cattcttgca aatgctagtt
     5401 atgcctttag tgtttatttc gatcattggt gcattcacaa aaatgaaagt ttctgaaaag
     5461 ctagggaaaa ttagtgcgac tgtattgact tctttacttg gaacaacagc tattgcagca
     5521 ttgatcggaa ttggttcaac aatgctgttc ggactccaag gagctaaatt cacacaagga
     5581 gctgcagaaa cagcacgaat ctctgaactg gcaacacgtc aggaaacagt tgaaaactta
     5641 tcgattccac agcagatttt atcctttatc cctaaaaacg tttttgctga tttagcaggt
     5701 agtcgtgcaa caagtacgat tggagtcgtt attttcgcgg catttgtcgg aatcgcttat
     5761 ctaggcgtga aaagaaaagc gccaaaagaa gcagcattct tttcagattt agtcgacagt
     5821 ctgtataaaa tcattatgcg gatcgtgacg cttgttttgc gtttgacacc ttatggagta
     5881 tttgctttga tgacaaacgt tttggcaaca agtgattttg cagctatcgt caatttaggt
     5941 aaatttgtcg ttgcttctta cgtagcattg cttgctgttt tgattgtcca ctcactgatt
     6001 ttgattggtg caaaagtcaa tccaatcaac tatttcaaaa aagcctttcc ggtattgagc
     6061 tttgcgttta cttcacgttc aagtgctgga gctttgccat tgaatatcga gactcagaca
     6121 aaagctttag gagtagatga tgcaacagct aatttctcag caagttttgg tttgtctatt
     6181 ggacaaaacg gctgtgctgg cgtttatcca gctatgttgg caacgatcgt cgcaccagca
     6241 gctggagtga atgtctttag tttggaattt attttgatgc ttgtggcaat tgtaacaatc
     6301 agttcttttg gtgtagctgg agtcggtggg ggcgcaacat ttgcttcact gatcgtttta
     6361 ggggcaatga acttgccagt agcaatcgtt gggttagtta tctctgttga accattaatc
     6421 gatatggcac gtacagcagt aaacgtcagc ggtagcatgg tagctggtat cgtgacaagt
     6481 gcacgcatca aagatttaga tcgcgatgtc atcaatgatg attctaaagt gatcgatgtg
     6541 aatgcatagt caaaaagagg ttgtgataga agtggtcagc tttaagaaat aagaagaagt
     6601 ttcctaaaaa tagtttctca aatttttgtg aaatttcggc ttatttccga gaagctactt
     6661 ctgaaacacc gtgaataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     6721 ccaaacaaaa atagttcctc atattttacg tttggttgag cttattaccg cagatgcaag
     6781 cttttgaaca ccgtttaaga aagaggtcgt gagcctgccg tttcactctg agtcacaaag
     6841 agcaatttca aaaaatagct tctcatgttt gttgaatatt gtgtcttgtg accgaggagt
     6901 tgtcaggaga acaccgttta ccagaggttg tgacttgttt ttagtcacga cctctttttt
     6961 tatttattcc atataaatac acattattta ttccgaaaag tgaaagcgca aataacaaaa
     7021 acaaccaact tatttattat taaagaaaag cgtatttaag taggacgatt ctgttgagag
     7081 ctttcgtaga ttttcccatt ttcctatggt aaactgacaa agttgagaat gttagaacag
     7141 atcgtttagg aggaaacaga tgtttacgaa tgaaataaaa atcatgcttt atgtggacga
     7201 tgtagaaaaa aatgcaacgt tttggagagc agttggcttt gcggaaaaag atcgtcaaga
     7261 aatggatggg acgcttataa ttgaagtagg agttgaggac agtcaaacct catttctgtt
     7321 atatgatcga gcatttgttg agtcccattc acctggcaca gctactagtg ccccatcttt
     7381 gatgttttac agtaaagata tctttggact atataaaaaa atgcagacgc aatcagtcac
     7441 attaggtgat atggtacagc ttggagaaga atatgtcttt aactttgctg atcccgatgg
     7501 caactacttt gcggttacag gtaaataata gaaataaaga ctttgttttt ctgtgcgaaa
     7561 caggaaagcg aagtcttttt aattcaaata ataatattat gtaaacaaaa aactttccat
     7621 gcgtaattat acacaagcaa ataaatcgtc aaatgcgaac gccttcttta tactgtttag
     7681 gaacgaaaag aaggaaggaa gaaatacatg gattatcaag tactgcttta ttacaattat
     7741 acaaaaatcg aagaaccaga ggaatttgcc aaaaatcatt tagccttttg caaatctttg
     7801 gatcttaaag gtcgtattct agtagctgaa gaaggaataa atggtactgt gtctggaacc
     7861 gttgaaaaca cgactgccta tatgaaagca atgaaagctg atcctcgatt tgctgatacg
     7921 atgttcaaga tcgatccaag cgaaggacat gcctttaaga agatgtttgt aagataccgt
     7981 ccagagcttg taagtttaaa gctagaagag gacattgatc caaaccaagt gacaggtgcc
     8041 tatctttcac cgcaagaatt taaagaagct attttagatg aacagacagt ggtgattgat
     8101 gcacggaatg attatgaata tgacttggga cattttcgag gggctgtacg cccagatata
     8161 cgcagttttc gagagcttcc agactggatc cgcgagcaca aagaagaatt tatggaaaaa
     8221 cgggtagtga cctactgtac tggtggcatt cgttgcgaga agttttctgg ttggcttgtc
     8281 cgtgaaggat tcaaagatgt cggacagctg catggcggta ttgctactta tggtaaggat
     8341 cctgaagtcc aaggagaatt atgggacggc aagatgtatg tgtttgatga acggatcgct
     8401 gtcgatatca accaagtaga taaacaaatc gtcggtcgcg actggtttga cggaacacca
     8461 tgtgaacgat atatcaattg tagcaatcct gagtgcaatc gtcagattct tgcttccatt
     8521 gaaaatgaag aaaaacattt aggagcatgt agcatagagt gtgcgaaaca tccgcgcaat
     8581 cgctatgttc aagaccatgg aatctctcca gaagaagcag aactgcggtt tacagcttta
     8641 attaaataga aaacaatagt tttgattgtc gaccatttcc aatatgcgct atactagcgt
     8701 tgaggatggt gatccacatg aaatcattga tttatgctat tggggatgtc catggcaaac
     8761 atgagctttt tgaaaaactt attcactatt atgatccaaa gatccatcag cttgttttat
     8821 taggggatct caatgatcga ggtcctcgta caaaagaatg ttttttatta ggaaagcaat
     8881 tagtcgaaga aacaggagcc atttacctcc ggggaaacca tgaagaatat tttttgcaat
     8941 ttctgcaatc accggaggac tggtatgcgc cttatatgag aaatggtgga aaagaaacgt
     9001 ttgaaagcct gattcaccca ggggcatcgg aggaatactc cccaactgaa atctcgatga
     9061 tgatccaatc gagatattca gaactgatta aatttttagt ccagcgcccc ttgtattatg
     9121 aatgggaaaa ttatcttttt gtccatgccg gtgtggattt gacaaagaaa gactggcgta
     9181 agacaagtct aagagacttt atttggataa gggaaccatt tcatgaaggg aaaaacaata
     9241 caggtaagac aattgtattt ggacatacga ttacaccaat gctccatgga gatatgcaga
     9301 caacagacct ctggattcag gatcataaaa tcggaatgga cggtggggct gtattcggag
     9361 ggtcattgca tggggttgtt tttgacaagg aaggtattct tcaagatatt gaatatcaga
     9421 acaacgaagg accttggcat ggaatctgac taatggaaag aatgaaggag ctgtgacttt
     9481 gttgcggctc tttttatttt tatagagaat attgtttctt tcagtagttt aacccaggat
     9541 aaaaagtatg atagaataaa gaagcaattt ttagcagaaa agaggcattt taatgacgga
     9601 aaatttgaac cagacgatca ttcagcttgt acaaaaagaa ctttcagact atcgtcctaa
     9661 gcagttgact actgtactta atttgttaaa tgaaggaaac actgttcctt ttatcgcgcg
     9721 ttaccgaaaa gaaatgactg gaagtcttga tgaagtccag attcgtgaaa tcgaagagcg
     9781 gtatgcctat cttgaaaact tagaaaaacg taaaactgaa gtgattcggc taatcgatga
     9841 acaagggaaa ctgactcccg agttagaagc agaaatcacc caagccgtga aaatgcaaca
     9901 agtggaagat ttgtatcgtc catacaaaca aaaacgacgg acaaaagcaa cgattgctaa
     9961 agaaaaagga cttgaaccac tcgcgaagtg gctgatgcag cttacagatg gagaggtgca
    10021 atctgaagca gaaaaatata ttgacaaaga aaaagaagtc tcttctgccg aagaagcgtt
    10081 gcacggtgct catgagatta ttgctgaaca agtcagcgat aatgcaaaat ttcggacttg
    10141 gattcggtct tatacgtata acaaaggtat gtatgtcagc aatgtcaagg atgagcaagc
    10201 agatgaaaaa ggcgtatatg aaatgtatta tgactttgca gaacccgtcc ataaaatggt
    10261 ttctcatcga atattagcta ctaatcgtgg agaaaaagaa gatattctga aagtattctt
    10321 tcaagtagat gaagcagcaa ttttagctta cttggatcgc caaatagtca aaaatcctgc
    10381 ctctccttct tcttcattcg tcagagaagc ctatcaggat agttataaac gctttattca
    10441 gccagcaatc gagcgagaac tgcgcaatga attgactgaa aaggcagatg agcaagcaat
    10501 cgctattttc ggcgaaaacc tccgtaatct tttgttgcaa ccgccactaa aaggtaaagt
    10561 tgtcctggga tttgatccgg cttatcgtac tggatgtaaa ctagcagtcg tagatgcgac
    10621 agggaaagtt ttagcaatcg aagttattta tcctcataaa cctgcagcgc aagcaaaaag
    10681 agaagctgct ggaccagctt ttatccaatt aattaataaa tatcaagtag atatggtagc
    10741 tatcggaaat ggtacagcca gtcgggaatc tgaacttttt gtggctgagc agttgaaatc
    10801 cgccgaccat aaaacctatt acgctatcgt caacgaagca ggcgcttctg tttactccgc
    10861 tagcgaaatt gcacgaaaag aatttccgca tctacaagtt gaagaaagaa gtgctgtttc
    10921 tattgcccgt cgcctgcaag atcctttagc tgaattagtc aaaatcgatc ctaaagctgt
    10981 cggagtaggc cagtaccaac atgacgtttc tcaaaaacgt ttggctgaac aattggattt
    11041 tgttgtggaa acagcggtta accaagtagg tgtggatgtg aatacagcaa gcccgcagct
    11101 cttgcagcat atatcaggat tgaataaaac aactgcccaa aacattgtca tttatcgtga
    11161 agaaaacgga gaattcaccg cacgaactca attgaaaaaa gtgccacgct taggaccaaa
    11221 agcatatgaa caagcaatcg gattcttgcg agtccctggt gggaaaaaca ttttggacaa
    11281 cacaggtatc catcccgaaa gttattctat tgcaaaagaa atattaactt cagtccaact
    11341 ttcagaaaaa gagcttggta cagaagaagc agtagaaaaa ttgacacgat tatccgtaga
    11401 gaaactggct gaaagcctat cagtcggaga agaaacgtta gccgatattt tagctgggct
    11461 gacacaacct ggacgagata tgcgtgatga gatgccagcg cccttattac gtacagatgt
    11521 attgagtatg gaagacttga aaccagggat ggaattgact ggaacggtcc gtaatgtcat
    11581 tgacttcggc gcatttgttg atatcggtgt gaagcaagac ggacttgtcc atatatcgaa
    11641 actcagcaaa aaattcgtca agcatcctac agatgtcgtg tcagtaggag atatcgtaac
    11701 agtttggata gaacaagtcg atacgaaaaa aggcagaatc agtttgacga tgctttcccc
    11761 ttatgaagag taacaatgag gagtaacaaa aattgacaca agaagaactg cagcagttag
    11821 tagaagagat atcattaaaa agcttccagc ttcctttcaa gcaccaagca atgttcaatc
    11881 cacgcttacg tacaactggc gggcgctatc atttaaacga tcatcattta gattttaatg
    11941 cgaagctatt tgaagagtca gacgaagaga cgattgcagg aatcatcaaa catgaacttt
    12001 gccattatca tcttcatcta gctggaagag ggtatcagca taaagatatg gatttcaagt
    12061 atcttttgaa aaaaacagga gggttgcgct atgcaccagc cttgacgaag aaacagataa
    12121 agatggagta ttatcgatgc caagattgtt ctgccacgat ctgccgcaag agaagaatcg
    12181 atgtacgcaa atatcgttgt ggaagatgtc atggagaaat caaatggatt gagacaaaaa
    12241 gagaagactt taatgaagca caaaaaatca gatgaaagga tagaaggcct ttggaaaaaa
    12301 gtgagcagag gaatctaaaa gactggaatc agctattaaa ttttttagcc gcacctgaag
    12361 agggaaattt tgaggaactg acggcaccta cacttatttt agctggaaac tgtcttccta
    12421 tcttagctga taaagcagca caaatgtatt taaatggcca agtagatcaa ttgtttttgg
    12481 tcggaggggt ggggcatgcg actagaatcc tttatgagaa ttttgaaaag caaggatttc
    12541 attttgaaga tggcatgagt gaaagtgaaa tctgtcgtca gtatctaaaa gaagtctatg
    12601 atttgcccga taaggctttt ctgatagaat cgaagtctac aaattctgga gagaacgcca
    12661 ctttttcact ggagattctt cattccttag gagctgtacc agaaaaaatc ttattgatga
    12721 atgatccgac actgcaacgc aggactcgag caacttttga gaaagtatgg caaaatgaac
    12781 aaactatttt cgcgaatgct gtgccatttg tgccggaaat ccttcacttt tctgaagaga
    12841 tcatctttac agcaaaagaa ctgaatcatc aatggcctaa ggaatatttc catgcgctag
    12901 tattaggaga aatggaacgt ctccatgacg atgagaacgg ctatggtccg aaaggaaaag
    12961 attttattcc tcacattgat atatcagagg aagtttggtc ttcttacacc agaattaaag
    13021 agtcaataaa aacggatttt tctcgtactt gaccatttta gcaagcgaat cctcctttcc
    13081 aaataaattt ggttgaaatt ttcaatcgtt tataagataa tgaggagcgt gttgaatgta
    13141 atagctaaaa gaatggacgc tagataagag aagaggattc aaatggaaaa tcaaaataaa
    13201 ttgtatcatt ttgttggtat caaaggttca ggaatgagct ccttggctct tgttttacat
    13261 gaacaaggtc taaatgtcca aggatcagac attgaaaaat atttctttac acaaagagat
    13321 ttagaaaaag caaatatcac gattctgcca tttaacgcag ataatgtaaa accagggatg
    13381 acgatcattg caggaaatgc atttcctgat tcacatgaag aaatccagcg agcaaaagaa
    13441 ttaggtttgg aagtgattcg ctatcacgac tttattggtc attttatcca aaattatacg
    13501 agtatcgctg taacaggctc tcacggaaaa acaagtacga ctggactgct ctctcatgta
    13561 ttgagtggtg tccgtccaac aagttatcta attggagatg gaacaggaca tggtgatccg
    13621 caagcggaat tcttttcatt tgaggcctgt gaatatcgcc gtcatttcct tgcctattca
    13681 ccagactatg caatcatgac caatatcgat tttgatcatc cggattatta tacaagtatc
    13741 gacgatgtat ttacagcttt ccaaacaatg gctggacaag tgaaaaaagc tatttttgcg
    13801 tatggtgacg atgcttattt acgcaaatta aaagcaaatg tgccgattta ttattatggt
    13861 gtcacagaaa acgatgatat ccaagcacga aacatcgaac gcacaacttc tggttctgct
    13921 tttgatgtct atcatgggga tgaatttgtt gggcacttca ctgtaccagc attcggtaaa
    13981 cacaatatct taaatgcttt aggtgttatt gcagtagctt atttcgaaaa actggatctg
    14041 aaagaagttg cagaagaaat gctgactttc ccaggagtaa aacgtcgatt cagtgaaaag
    14101 atcgtagcag acatgaccgt agtcgatgat tatgcgcatc accctgcaga gatcaaagca
    14161 acgattgatg gcgcacgcca aaaatatcca gataaagaaa taattgcagt tttccaaccc
    14221 catacgttta cgcgtacgat tgcattgatg gatgaatttg cagaagcact tgatttagct
    14281 gataaagttt acttatgcga tatttttggt tcggctcggg aagaacaagg aaacgttaag
    14341 attgaagacc ttggagcgaa aatcaaaaaa ggtggagaag tcatcaaaga aaataatgta
    14401 tctccattgt tagattatca tgatgcagta gtaatcttca tgggtgctgg agatgttcaa
    14461 aaatttgaac aagcgtatga aaaactttta agcagcacga cgaaaaatgt actgtaatac
    14521 aattactgca gtgtccttat aaaaatagaa agagggggag tggcaaaaat cttgccaagc
    14581 cccctttttt gcaacttatg ataaacggtg ttcaaaagct tgcatctgcg gtaataagcc
    14641 caatcaaatc aaaaacatga gaagctgttt tttcttggct gttcttatta tttgatgcag
    14701 gacagctttt tcacgacctc tgtaaactat aggaatctgt taaatcaagg gagcagaact
    14761 tgccttttac gctacttttg gtacaataat gtatgattaa aaataaactg gagggtttct
    14821 atcttgaaca taggtaagcc gagaaaacta ggaaaaacaa taaatgaaat cgaggaaggc
    14881 gactcgttat ccttaacaga atctattgaa gataaccagc ttttgctgta tttgggattg
    14941 acgaatgatg caaatccttt gtatatccaa catgactttg cacaaaaaac agaatatcaa
    15001 cagccaatcg ttccatcagt gatgctgatg gggatcatca caagtgcaat ttcaaagcat
    15061 cttcctggac caggatcaca tgttgtcaat ttttctgtca attttattga accggttttc
    15121 cattatgaaa cactgacttt tcagtttgag gtcataaaag tagataagat gaaggatgtg
    15181 gtgacgattt ctgtagaagc ggagaatacg aacgaagatc gtgtgttgga tgctgtcgtt
    15241 atggtccaac cgccacaagt tcctgaattg gaaatagcaa tcgaaagtga aggtgaattg
    15301 aatgaataat ccaagtacat caatgtcagg tatcaatcgt ttttatgcaa aagtttatgg
    15361 atttttaggt atgggacttg cccttagtgc agtcacttct tacttggctc tttgggtatt
    15421 tcctttgcaa ttagcaactt ttatcaataa ttttccacta ggctttgtgg gtctgtggat
    15481 cgttgaactg attttagtaa tggttctagg cgtaaaagca caaaagaatc cgagcttagc
    15541 aatcggtgga tttattgcct actctctttt gaatggcata acattagcgg ttactcttgc
    15601 atactacgat attggaacag taacgcaagc tttcttgaca gctactttga tgttcatggg
    15661 gatgtctgtt gtcggagtaa caacaaaaag agatcttagc ggggttggaa gagcaggaca
    15721 ggcagcttta atcggagtga tcattgcact agtcttgaac atcttcattt tgagaagtag
    15781 cgtagttgag ctgttcatct ccctactgtt agtcgtcatc tttgcaggga ttacagctta
    15841 tgataaccaa agcatccgta atatctatgt ccagacaaac ggaacagcac atagtggaat
    15901 tgctgtattc atggcattga agctgtattt ggactttatc aacttgttct tggcgtttct
    15961 gagaatcttt ggacggaaca actaaaaaag aaaaaaattc atcagttggg gctataccga
    16021 attatttggt atggtcccgc tttttctttt cgcattccgc aggattcttt gttagaatga
    16081 ataagaactt tacagtaagg agttaagaag atgacaaaaa ataaattatt actcgttgat
    16141 gggaacagtg tggcttttcg cgcattcttt gcgcttcaca attctcttga acgtttcaaa
    16201 aatagaaacg gtcttcatac aaatgcaatc tatgcattca atacgatgtt tgaaaatgtt
    16261 atgcaaaaag agcaaccgac tcatgttctg gttgcgttcg atgcaggaaa aacgactttt
    16321 cggacagaaa tgtatgcgga gtacaaaggt ggaagatcca aaacacctgg cgaattcaaa
    16381 gaacaaatgc catatatacg tgatttgttg acaggactag gggtacagta ttacgaattg
    16441 cccaattatg aagcagatga tattatcggt actttggcag aaaaagtaga caaagatcaa
    16501 tttgatgtcg tcgtgctttc aggtgatcgg gatttgactc aattagctag taaagaagta
    16561 aaagtggata tcactgtaaa aggtgtcagc gatatcgaaa gctatacacc agaacatgta
    16621 gcggaaaaat atgatgggtt gacgccaaaa cagattattg acatgaaggg actagccgga
    16681 gatgcctctg acaatatccc cggtgtgact aaaatcggtg aaaaaacagc tatcaagcta
    16741 ttgaaacaat atggctcagt cgaaggaatt tatgaacata tcgatgaaat gaagcaaagc
    16801 aaaatgaaag aaaatctgat aaatgacaaa gagcaggctt tcttatcgaa aaaattggcg
    16861 accatcaata cttcagcgcc tgtggatgtc tctatcgact cattgaagta tgaagggaaa
    16921 aatctcgata aactcgttcc gttttataaa gaaatggatt tcaatcagtt cctttctaaa
    16981 ttgaatatcg tagaagaaga agtaaaaatg gatgatattt tgtttgaagt cgttcatgaa
    17041 ttcaaagagg aaatgtttac tacggatatg gcgttgtacg tggaaatgat gggcgacaat
    17101 tatcatacag aggaaatcgt cggagtagcg tgggggacag aaaagaaaat ttatgtcacg
    17161 aacgatctat ctgtattcga aaaccgagcg ttccattctt ggatcactga tccgactcgg
    17221 ctgaaaaaag tatatgatgc gaaacgaact tatgttgctt taaaccgcta tactggaaaa
    17281 acgaaaggaa tcgattttga tgtcttgcta ggtgcatacc ttctcgatac gaatgaaaaa
    17341 agcacagata tcgaaggaat agctgctcat tacggataca acgatatcca atcagatgaa
    17401 gctgtatacg gcaaaggggc gaaaaaaggt ttaccagaag aagaggaact cttttttgct
    17461 catttagcgc gaaaagtagc tgcaatcaat gcgttgacac caaaattgag ccaagaactg
    17521 gcagaaaaaa accaagaaga tcttttccgg aaaatggaac tgccattgtc tatcattttg
    17581 gcagagatgg aaataagcgg gatcaaagta gatgcgactc gcttacaaga aatgaagggc
    17641 gagttctctg ctcgcttaag agagatcgaa caaaaaatct acgaagaagc cggcgaagaa
    17701 ttcaatttga attcaccaaa gcaattagga gtgatcttat ttgaaaaaat gggattaccc
    17761 gttatcaaaa aaacaaaaac tggatattcc acagccgtag atgtactgga acagcttcgt
    17821 gaacaagcac caatcgtaga ggatatcctc acctatcgtc aaattgcaaa aattcaatct
    17881 acctatgtcg agggactgct gaaagtgatc caatcagatg gaaaagtgca tacccgttat
    17941 gtccagacat tgacccaaac aggacgatta agctctgttg atcctaattt gcagaacatc
    18001 ccgattcgat tagatgaagg gagaaagata cgtcaggcat ttgttcctag agaaaaagac
    18061 tggctgattt attcttctga ctattcacaa atcgagttac gcgtacttgc gcatatctca
    18121 aatgatgaac atttgaaagc tgccttccta gaaggtcaag atatccatgc cagcacagcg
    18181 atgcgtgtat ttggaatcga aaaggcagag gatgtcacac caaatatgcg taggcaggca
    18241 aaagcagtga attttggtat cgtgtatggc atctctgatt acggactttc acaaaatcta
    18301 ggaatcagcc gaaaagcagc acagcaatac atcgatacgt actttgaaaa atacccaggt
    18361 gtcaaagaat atatggaaag aatcgtacgc gaagcaaaag accaaggcta cgtcgaaacg
    18421 ctgtatcacc gccgtcgata tctgccagac atcaattcaa gaaattacaa tatccgttct
    18481 tttgcggaac gaacagctat caatacacca atccaaggaa gtgctgctga tattttgaaa
    18541 atcgcgatga tcgaattgga taaacgatta aaagaaacag gtcttcaagc tacgatgctg
    18601 ttacaagttc atgatgaact tgtcttcgag gtaccggaaa aagaacttga atcattagat
    18661 aaattggtga aggaagttat ggaacaagct gtttctcttc atgtaccact gatcactgac
    18721 agcagttggg gaaaaacgtg gtacgaagca aaataaacat tgtttaagac agagcaatat
    18781 aatgaaggtg aaaagaaaaa atgccagaat taccagaagt agaaaccgtt cgtaaaggat
    18841 tggaacggtt agtagtagga aaaacgattc aaaaagttca ggtcttgtgg cccaagatca
    18901 tcgagcaacc agagacaccc atctttgagg cttctcttgt tggcgaaacc atccaatcca
    18961 ttggacgtag agggaagttt ttaatttttc atctcgatca ttgtgaactg atctcacact
    19021 tgcgaatgga aggaaaatat caatttacga aagaaaatac accaatcgat aaacatacgc
    19081 atgtactttt cttttttgag gatggaagcc aacttcgcta caacgatgta cgaaaatttg
    19141 gtcgtatgac aatcgtcgaa aaaggagcaa gtgcaactta ccgaggaatc atgaaattgg
    19201 gacctgagcc tttgccagat agcttcttat tagcagattt cgcaaatgga ctgaaaaagt
    19261 cccacaaagc aatcaagcca ttgctgctag accaacgtct agtgactggt ctaggtaata
    19321 tttatgtaga tgaagcatta tgggaagcga agatccatcc agaacaaccg gcgaacacac
    19381 tgcgccccaa agaggtagaa caattacgtc tatcgatcat tgatgttttg gatcgtgcaa
    19441 tagaagccgg aggtaccacg attcgcagtt atttgaatgc attaggagaa tcaggcggat
    19501 ttcaagtagc actgcatgtc tatcagcaaa ctggcaaacc atgtatacgt tgtggaacgc
    19561 cgatcgtgaa aacaaaagtg gcacaaaggg ggacgcacta ttgtccgaat tgtcaaaggc
    19621 taaaaatcgc aaagtaggat ttgttttagg tttgacgggt ggaatagcta ccggtaaaag
    19681 tacggcagcc aaagtctttc agtctcatgg atttcctttg atcgatggcg atgtgattgc
    19741 cagagaaact gttgagcctg gaacgcttgc tctgaggaaa attgtatcag tgtttggcca
    19801 agaggtattg cagcctgatg ggcaactaga tcgagggaaa cttgggatga ttgtttttcc
    19861 atcaaaggaa aaacggcaaa aacttgatca gctattagat ccgtttatcc gaaaagcgat
    19921 aaaagatcaa atcgcctctc taagttccaa tcatccttta gtaattgtag atatcccatt
    19981 gctctacgaa ggtcattatg accactatat ggatgcagta gctgtcgttt atactacgcc
    20041 agaaactcag cttcagcgtt tgatgaaacg taatcaactg acgctagaac aagcgcagca
    20101 gagaattagt agtcaacttc caatcgaaga aaaaaagcag cgtgcggata ttttgttcga
    20161 caacaatgga acaaaagaaa tacttgtggg acaaatcgaa aattggcttt ttgctaatcg
    20221 ctttctttga gtatctgtgt caattttgct atcctgagta tatagaaagt gagggatagc
    20281 gatgggatca ttaaaaaatc aaaaggataa agtcgtaggt aacgcaaaag aaaaaatcgg
    20341 cgagatgctc aataaagaaa atctaatcga tgaaggtcgt acgcaatcag aaacagcaga
    20401 agaaaaagaa aagcagtacc aagcaagaat cgatgaaata gaagaccagc aggcagaaga
    20461 agaagcgaag cggcaagatt tgactcaaga acgaaaaaat ccgacacctg atcgtagtaa
    20521 aacaccgctc ccagaaagtg accacattcc cgatgagcaa aaaatcgagg aacagcgaat
    20581 gaaacactat acaggaatcg aagagaagtt ataaaatagt aaaaaatcga gatgtgactt
    20641 gaagcagatg agaaggtgtt catctgcttc aagttttttg tgctagatga ctaaatcagc
    20701 ttttgtgtaa gttatttctc agtaatcaag gtgatcagta ttggaaaatt gaaatttagt
    20761 aaggacaggg gacacaatta cgcatgaaag tagaaaaaat tgttcttata tccgtgtttt
    20821 ttgggtagga cagtcgcgtt tgtgatttgt ttcgtgttat aatacaacta gttgtaaaga
    20881 aagacacatc ctttatataa aatgcgatgc aagaggtgag acaaaatgag atgtcccaga
    20941 tgtcaacata ataattcacg agtaatcgac agccgtcaag cagatgatgg acgtgcgatc
    21001 cgtcgccgtc gcgaatgtga gaattgttcg ttccgattca ctacatttga acgaattgaa
    21061 gctgctccgt tattagtaat caagaaaaac ggggaacgcg aagagttcaa tcgcgataaa
    21121 attttaagag gactcatccg ttcagcagaa aaaagacctg tagctatgga acaaatggaa
    21181 caaatcgtca accatgtcga aaaccgcgta cgcagtctcg gagaaaacga agtatcgacg
    21241 aatctaattg gtgaatatgt gatggaagat ttagttgatt tagacgaaat cgcttatatt
    21301 cgttttgcaa gtgtttatcg ccagttcaaa gatatgtctg ttttcttaaa agagttgcaa
    21361 gatatcgtgg ataaagcaaa agaaaataat aaagagaata ataaagaaaa caattaagaa
    21421 acaaaaagga ggcatttcct tggaaaatgc ttggaaagag cttcaaccaa aaaatattta
    21481 ccaaggaaga aaagcggctc cgctgagaga agacagcaag aacgccttgc tgtatcttta
    21541 tcagccacta atcggcggag aagccttgag tatctatttc accctgttat cagaaatctc
    21601 tcaagaatct ggcaaaggtc ctgaagggat gcatgcagat ctgcttagta gtctaggctg
    21661 cggtatcccg caattttatg atgcaagaaa aaagctagaa ggaatcggct tactggatgt
    21721 ttattttaaa gaagatagtg atctgggacc tcgttttatt tatgagctgt tagaaccact
    21781 cattcctaaa gcatttttca aagactctgt tctggctttt cttcttctgg aaaaagttgg
    21841 tgaacgacga ttccagaagc ttacccaatt ctttgaacct aaaaggcata cagcagaggg
    21901 atatcaaaaa atcacaaaaa aatttttaga tgtttatcgc ttcaatgaag cagtgtacgc
    21961 tgctaatcaa gaaaacatcg aatcgctgaa taaatctttt gaagaatctg aatcagtagc
    22021 attacttgaa gcagattcga cattcgattg gcagtttttg aatgattggc tggcaaaaaa
    22081 acatattgca agtcttgatg atccaatcat caaacaagtc gacatgtatc atcagcttta
    22141 cggtttcgat gaattgacac ttggcgaact gatcagtcaa tcttatgact ttagtgaaca
    22201 aaaagtatct gaaaaagaac tgcaaaaagc cattttggca atgcagagac gtccggtgaa
    22261 gcaaacaaaa gaaacagttg cggtttctga aaacagtaat gaaccctcgt caaacgaaca
    22321 tttgacaaac gcagcgcttc agctgataaa agaagcacag agcattccac cgatgaaata
    22381 tctggaagca atcaagtcag aaaaaggcgg atatgtttct aaacaagaaa actggttact
    22441 gcaagatctt gtttctcaat caggtctttc cagtagcgtg atcaatgttt tgctgaatta
    22501 tgtactagtg atcaagaata atgctagctt aaatgccagt tatgtaaata cagtggcaaa
    22561 tgaatgggca caaaagaaaa tcgccacagc agaagaagcg atccagcaca ttcggcaaat
    22621 aagtaatcaa gcaaaacaat caaaacaaaa gaagcaaaca aattatcaaa ctggcaagcg
    22681 aaatgttcga cgggaaaagc ttcctgattg ggtcaaccag ccaaaagatg aaaaacagat
    22741 cagcagcgag aaaaaagcag agattgaccg ccgttttaaa gaatacctgg caaaaaagga
    22801 gggtgatatc tagtggaaga cgtaggcaaa gaattgaaga ggatcatcag caaacgcaat
    22861 tatcaagaaa agtatgctga aatgatcgct gaagtcttaa atgatgcgga tgttcaagct
    22921 tttctaagcg cacaccaaga agaattgaca caagcggata ttgaaaaaag ttacgctaaa
    22981 ttgtatgaat tcgtgcaaga aaagcgtaaa tatcaaaaaa acgatccaac gatgatcgct
    23041 cccggctatg agccgaagct gacgttgaat tttcattatg tggatgtcac ttatgtacca
    23101 acggaagcat tgttagcacg gcaaagacaa gaagaaatca gaagccgagt aaaagcaatg
    23161 gatatgccaa aagatattca atcggcttct tttgaaaact ttgaacgtac agatggacga
    23221 ggatatgcga gcttagaagc cctagatttt gtagagaaat atactgctga tccaaaaggg
    23281 tatcataaag gactgtatct agtaggaagt tttggtattg gaaaaacata tttattagga
    23341 gcaacagcga gagaattagc gattgctgga ttcaccacga cgctagtcca ttttccgaca
    23401 tttgccgttg agatgaaaca ggcaatcgga aaagatcaag tggcagaaaa gttagatgca
    23461 gtgaaacgtt cacctatttt gatgatcgat gacattggtg cagatgcgat gagtagttgg
    23521 atacgagacg aagtattcgg tgttatcctt caatatcgga tgcaggaaca gttaccaacc
    23581 ttcttctcat cgaattttac aatggatgaa ttggaacagc atttgtccgt cactcaacgt
    23641 ggagatgaag agccgctaaa agcgaaacgg ataatggaac gcatacgtta tttgacaaaa
    23701 gaaatcgaaa tgactggtcg caaccgacgc aatggttgaa cagttgacaa gtccaactga
    23761 catttgacct agtagtaaaa gcaggtcagc gaatcattat atggacagaa atgaccggag
    23821 acaatcaccg caacaagtaa tgcagaaact taaacggagg attttttatg agggctattt
    23881 tttctagtat atctgtagtt ggtctatttt ttcttttagc aggctgcggt agcgcagata
    23941 gcaacacagg ttctgttgat tcgattgatg cgggtcaaac agtaaaaaca agcagtacga
    24001 aaacggagag acaaagcata tttgtcggaa cgattgaaag tatcactcaa gtagaagcag
    24061 aagaagaaac gcttcagttg aaactcgtcg atgtcatggc caaagaagat ccagcgaata
    24121 tgggaacgtc attcagcaat gacggagtga tcttaaatgc tactgctgaa aaaataagcg
    24181 tggacataaa tgaattgaaa atcggtgaca aagtccaatt tacattagtt gagatgccga
    24241 tcatgacgat gtctatccca ccgcaagttc ctggagattc gattattgat gtttcattga
    24301 acaaataacc aataacattt tttcaaaaat aagaaaatgt tgttttatag aacgaaaagg
    24361 tatatttttt aaggagatat gggaattttt ttattcctag tctccttatt ttatttggaa
    24421 aatgctataa ttatctagaa ggagtgaagc tatgaaccat ttagatttat ctcagcgctt
    24481 agccgcagtg ggtgactttg tccctgaatc cgctcgttta gcagacattg gatcagatca
    24541 cgcttactta cccgttgcat tgatattaag aggaaaaatc gaatatgcag ttgctggtga
    24601 agtcgttcaa ggtccttatg aatcagcacg taagcaagtc aaaaaagatg gattagaaga
    24661 ccgtatcacc gtacgccttg caaatggtct agatgctatc cagccacaag atggtattac
    24721 agctgtcacg attgcgggta tgggaggttc actgatccga gatatcctag aagctggcaa
    24781 gttgaatcaa cgcttaagcg gacaagaacg tttgatcctt cagccaaaca tcggagagcg
    24841 tacattacga tcttggctgc aagaaaatca gtataaaatc caatcagaaa aaatacttga
    24901 agaaaataaa aaaatatatg aaatcattgt agccgaaaaa gaacaaaaac cagttactta
    24961 caatgaaatg gagctgatgt tcgggccatt tctgcttgaa gagaaaagtg agatcttcaa
    25021 atcaaaatgg acaagagagc ttcaacaaag aaaagctatc cgtgaacagc tcaaacaagc
    25081 agctaatcaa gaggcacgtc aaaaacaaat cgagcaggaa atccaaatga ttgaggaggt
    25141 tttaaagcca tgacaatcag cggacgcact ttcatccaaa agtttgaaag ctattgtcct
    25201 cagtggctag ctgaagaagg agacccagtc ggactgcata tcggaacatt ggataagcca
    25261 atccaacgag taatgatgac attagacgtt cgtccagaag tggtcgaaga agcaatcaag
    25321 aaaaaaatcg atttgctgat tgctaaacat cctccaatct ttcgtcctgt aaaacggctg
    25381 gttactgatc agccacaaga aaaaatgtat gcagatttgt tgaaacatga tattgccgtc
    25441 tatgcagcac acacgaacat ggatattatt tgggatggac tgaatgactg gttttgtgaa
    25501 cttctcggta ttgaagtgga gagttattta gtaaagactc atgagattca ttataaaaaa
    25561 ctggccgttt atgtacctgt ggatcatgca cagaaaatgc gtgaagtatt agctgcagct
    25621 ggtgctggta cacaaggtga ttataccggt acaagtttta cctcgattgg acacggtcga
    25681 tttactccgg aagctggtgc acaaccagcg attgggaaag tagggaagac agaacaagtt
    25741 caagaggcaa aagttgaggt tattttgccg gaaactatcg aaaaacaagt gattcaagcc
    25801 atgcggtcag ctcatcctta tgaggaacct gcttatgatc ttttcgctat agatgaacca
    25861 gtcgaaatgt ttgggttagg acgagtaggt gaattgccgc aagaaatttc tatagaggca
    25921 tttgtagaac aagtaaaaga agcgttccaa ctagatggac tgagaatagt ccagccaaaa
    25981 aatgcaaaat cctctgtgaa gcgcattgcg atttgcggtg gaagcggtga aaaattttat
    26041 ccgcaagcaa tcgcccaaag agcagatgtc tatatcacgg gagatatcta ttatcatacg
    26101 gctcatgata tgcaaagcgc tgggttgatt gcaattgatc ccggtcatta tattgaatcg
    26161 ttatgcaagc aacgatttat cgagaaattt gaatcttgga aacaagaaga aaattgggat
    26221 attaactttt tcgtttctga aacaaataca aacccatttc aatttaatta aaaggagaga
    26281 atactatgta cgaaaatctt ttgccacgtt ttttacgata tgtcaaaaca gaaacacgct
    26341 ccgatgcaac aagcaaaacg actccatcga ctcagacaca agttgctttt gcgcaagaat
    26401 tgaaaaaaga attagaagag ttaggcttag ctgatgtttt ctataatgaa gataacggat
    26461 tcgttatggg aacattacca agcaatgttg atcatgaagt gcgttccatt ggatttattt
    26521 cccacatgga tacagcagat tttaatgcag taggagtcaa tccacaaatc attgaaaact
    26581 atgatggcga gtctacgatc gtactagatg cggaagaacg ctatacattg aatacaaaag
    26641 attttccaaa tttgaaaaat tatgaaggcc acacattgat cacaacagat ggcagtacat
    26701 tactgggagc agatgacaaa tcagggattg cggaaatcat gactgcaatg gagatcttga
    26761 tcaataatcc ttctatccct cacggtacca tcaaagtggc ttttggtcct gatgaagaaa
    26821 tcggtgtcgg agcggataaa ttcgatgttg agcaattcga tgtagatttt gcttatacag
    26881 tcgatggtgg tcctttaggt gagttgcagt atgaaacgtt tagtgctgct caagcaaata
    26941 ttacgatcca agggaaaaat gtacatccag ggacggcaaa agatacaatg atcaatgctc
    27001 tacagttagc aatcgatttt cataatcagc ttccagccga tgaagttcca gaaaaaacgg
    27061 aaggatacga aggtttcttc catttgatgg cattggatgg gaatcctgaa gaagcttcta
    27121 tgagttatat cattcgcgat catgatcgtg aaaaattcga agcacgcaaa gcacaaatca
    27181 cacatatcca agaagagttg aatcagcgat ttgatcaaga acgaatcaaa gtagatatgt
    27241 atgatcaata ttacaacatg aaagaaatca ttgaaaaaga tatgagcatc gtggaattag
    27301 cgaaacaagc aatgatcgag cttggtatct ctccagtgat cgaaccagtt cgtggaggaa
    27361 cagatggttc aaaaatctct tacatgggta ttccgacgcc aaatctattt gccggaggag
    27421 aaaatatgca cggacgattc gaatttgttt ctttacaagt aatggaaaaa gcaacagacg
    27481 tgattgtaaa aattgcagaa ttgaacacaa agagttaaaa tcgaaaaaga acagcttatg
    27541 acaaggcgtt cgtcccaatg atggaatgtc atctgtctaa ggctaaaggg caggacaatg
    27601 gaattggttg tcccgccctc ttttttgaag agtaaatagg aggtaaagaa tggaaaagct
    27661 gctagttttt tataacaaaa gttcagggaa agatgagggt gagaaattag cacgctggtt
    27721 tcaagattat gtaaaagaaa agcagccaga attatatgta gaactagctg aaactggccc
    27781 atcgattgat gatgcggaat tagtcaagaa agcagaagcc atagaagctg atactttagt
    27841 aattataggt ggagacggca cgattcatca tatcgtccaa gcgttccaaa aaacattatc
    27901 tcaataccat gtcggattac ttccaggtgg aactgtcaac aaccttgcac gtgttcttga
    27961 gattcccctc aaaaaagaag aagctgctga cgtgatcctg gaaggcaatg tacggaaaat
    28021 agactatggt caagtcaatg atgaagtcat tatctctaca ctgacaatcg gaatcttagc
    28081 agatacagca gtttggatca gtcaagaaga aaaacagcgt tacggctcgt ggatctttat
    28141 caagaagttt tttaagttat tgctgaagaa gaaaaaatat catttggatt tagaaacaga
    28201 cgaggagcat tggaaaggaa aatcccaact gttgacagtc acgatgtcta actccgtggg
    28261 cggttttaca aattttgacg actcagcgac cctagatgat ggaaaatttc atgtaacgat
    28321 cgtaccttcc ttagatattt tccgatttat tttttatttg cctagaatca tgagaggcaa
    28381 attctatacg atccccggca ttacttattt cacagccaaa cgcatgaaaa tccaagcgca
    28441 ggaaaaatct gtgggcactc gaacggatgg agacacgaca gatgatcttc cagttgaatt
    28501 atctgttgta tcaaaaggat taacagttta ttcaccaaag aaagaagaaa aagcttagaa
    28561 atagtagtta acagaaagtt ggaagaagag taatggatgt attgttacac aatcctttgt
    28621 ggttttacct tttcattgtg aatttttact tattttgtct gatggggtat gataaacatc
    28681 aggctagaac tagcggctgg cgtgttcctg agaataattt gatatttgtc agcctgttag
    28741 gcggtggttt gggaggattg atctctcgaa aagttttcca tcataaaact cggaaaaaga
    28801 agtttactat aggattcgct gcaggtgtac ttgttgattt gattctcatt tattttttcc
    28861 attaaggagc aggagatgtc gtctaaagga acgaaaacta aaatcattct gaatctgctt
    28921 ttgctgattg tgatttttgc cattatttat tatttaatca atcaatcatt tgcagatatc
    28981 tttgccgaat tgctgtctac cagtgttgtt gttttggcag cggctgttat attagggaca
    29041 gtttaccaaa tcgctgaagg gcgctcaatc aaagaaattg ctgaaccttt cgcgccgaat
    29101 tttacaacga aagatgggtt cttgacctct agctatattg cgttttaccg aatcgtttcg
    29161 tttggtacag gaacgctgat ctcggagatt tatttttata acaaaaaagg aatgaagcta
    29221 tcccagggag caggggtgac agcactccat atgattatgt acaaactggc agtgatcact
    29281 tatgcattag ctggcttggt catccaattc tctctttttt attctaatgg tccatcaatg
    29341 atctggttta tcatcgctgg tatccttttg acgatcgtga ttgttgcctt tttattggcg
    29401 atgtccgtca gcttgaatgt tcaaatattt tttgtcagct tatcgaataa gttatttaaa
    29461 agtgagcgtt tgcggaaatg ggtggataca tgcaatcagc agatctactc tttaagggaa
    29521 acggtccaaa ccattatcca agacaggact gcgctattgc ggatttatct atggaatatg
    29581 ttaaaacttg tattttggta tgtacttcct tatttgattc tgattgaaaa ccatcctaaa
    29641 atagattttc tactgaccat ttcgtttatc agctttgcag tagtgctttc aggggttatt
    29701 cctacgcctg ctggtattgg ttcctttgaa tttgtctatt tgttattatt cagaccagtt
    29761 gttggaacag ttgacgcagt ttcttcgctt ttactgtatc gtttcagttc ctttatcttg
    29821 ccatttctct atggatttgt gtatgtgatt gctgaacggc gaagagtgat caaagaagaa
    29881 ataatagaag taaaaaaaga gaataaagaa aatcaagggt aggtctttta taagatctac
    29941 cctttttatc aaatc
//
LOCUS       DADVXV010000029        29837 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.029, whole genome shotgun sequence.
ACCESSION   DADVXV010000029 DADVXV010000000
VERSION     DADVXV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.029"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..628)
                     /locus_tag="KB969_001211"
     CDS             complement(<1..628)
                     /locus_tag="KB969_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HBB6869213.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIK
                     IIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLK
                     IHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
     gene            complement(722..1771)
                     /locus_tag="KB969_001212"
     CDS             complement(722..1771)
                     /locus_tag="KB969_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6869214.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFTRGAS"
     gene            complement(1853..2542)
                     /locus_tag="KB969_001213"
     CDS             complement(1853..2542)
                     /locus_tag="KB969_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6869215.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(2648..3016)
                     /gene="rplL"
                     /locus_tag="KB969_001214"
     CDS             complement(2648..3016)
                     /gene="rplL"
                     /locus_tag="KB969_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBB6869216.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(3069..3572)
                     /locus_tag="KB969_001215"
     CDS             complement(3069..3572)
                     /locus_tag="KB969_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBB6869217.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3776..3903)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3982..4671)
                     /gene="rplA"
                     /locus_tag="KB969_001216"
     CDS             complement(3982..4671)
                     /gene="rplA"
                     /locus_tag="KB969_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBB6869218.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4775..5197)
                     /gene="rplK"
                     /locus_tag="KB969_001217"
     CDS             complement(4775..5197)
                     /gene="rplK"
                     /locus_tag="KB969_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBB6869219.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            5540..6208
                     /gene="sdaAB"
                     /locus_tag="KB969_001218"
     CDS             5540..6208
                     /gene="sdaAB"
                     /locus_tag="KB969_001218"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBB6869220.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            6221..7093
                     /gene="sdaAA"
                     /locus_tag="KB969_001219"
     CDS             6221..7093
                     /gene="sdaAA"
                     /locus_tag="KB969_001219"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBB6869221.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(7184..8203)
                     /locus_tag="KB969_001220"
     CDS             complement(7184..8203)
                     /locus_tag="KB969_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBB6869222.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(8376..9281)
                     /locus_tag="KB969_001221"
     CDS             complement(8376..9281)
                     /locus_tag="KB969_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6869223.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(9340..9885)
                     /gene="nusG"
                     /locus_tag="KB969_001222"
     CDS             complement(9340..9885)
                     /gene="nusG"
                     /locus_tag="KB969_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBB6869224.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9986..10156)
                     /gene="secE"
                     /locus_tag="KB969_001223"
     CDS             complement(9986..10156)
                     /gene="secE"
                     /locus_tag="KB969_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBB6869225.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(10180..10332)
                     /gene="rpmG"
                     /locus_tag="KB969_001224"
     CDS             complement(10180..10332)
                     /gene="rpmG"
                     /locus_tag="KB969_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6869226.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            10494..11138
                     /locus_tag="KB969_001225"
     CDS             10494..11138
                     /locus_tag="KB969_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6869227.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(11194..11697)
                     /locus_tag="KB969_001226"
     CDS             complement(11194..11697)
                     /locus_tag="KB969_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6869228.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(11710..11756)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            12294..13259
                     /locus_tag="KB969_001227"
     CDS             12294..13259
                     /locus_tag="KB969_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBB6869229.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(13358..14530)
                     /locus_tag="KB969_001228"
     CDS             complement(13358..14530)
                     /locus_tag="KB969_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869230.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(14517..15662)
                     /locus_tag="KB969_001229"
     CDS             complement(14517..15662)
                     /locus_tag="KB969_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869231.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(15676..16608)
                     /locus_tag="KB969_001230"
     CDS             complement(15676..16608)
                     /locus_tag="KB969_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869232.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            16725..17804
                     /locus_tag="KB969_001231"
     CDS             16725..17804
                     /locus_tag="KB969_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6869233.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17801..18419
                     /locus_tag="KB969_001232"
                     /pseudo
     CDS             17801..18419
                     /locus_tag="KB969_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(18529..18756)
                     /locus_tag="KB969_001233"
     CDS             complement(18529..18756)
                     /locus_tag="KB969_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6869234.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18859..21447)
                     /locus_tag="KB969_001234"
     CDS             complement(18859..21447)
                     /locus_tag="KB969_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBB6869235.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(21467..22126)
                     /locus_tag="KB969_001235"
     CDS             complement(21467..22126)
                     /locus_tag="KB969_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6869236.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(22175..22678)
                     /gene="trmL"
                     /locus_tag="KB969_001236"
     CDS             complement(22175..22678)
                     /gene="trmL"
                     /locus_tag="KB969_001236"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBB6869237.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22899..23765)
                     /locus_tag="KB969_001237"
     CDS             complement(22899..23765)
                     /locus_tag="KB969_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6869238.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23874..24515
                     /locus_tag="KB969_001238"
     CDS             23874..24515
                     /locus_tag="KB969_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBB6869239.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(24577..25938)
                     /gene="mgtE"
                     /locus_tag="KB969_001239"
     CDS             complement(24577..25938)
                     /gene="mgtE"
                     /locus_tag="KB969_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBB6869240.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25956..26855)
                     /locus_tag="KB969_001240"
     CDS             complement(25956..26855)
                     /locus_tag="KB969_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBB6869241.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26857..27654)
                     /locus_tag="KB969_001241"
     CDS             complement(26857..27654)
                     /locus_tag="KB969_001241"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBB6869242.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(27632..28336)
                     /locus_tag="KB969_001242"
     CDS             complement(27632..28336)
                     /locus_tag="KB969_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBB6869243.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            28467..29042
                     /locus_tag="KB969_001243"
     CDS             28467..29042
                     /locus_tag="KB969_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBB6869244.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            29160..29837
                     /locus_tag="KB969_001244"
     CDS             29160..29837
                     /locus_tag="KB969_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6869245.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8779 a         6292 c         5364 g         9402 t
ORIGIN      
        1 ttttatggct aatatatcct ttgtccccta ggatattggg aagattcgct tcttccgata
       61 aagtctctaa cactttcacg tcatggacac ctggattcgt gattgagtaa gtaatcggaa
      121 agccagtctt agtaacgatc atatgaattt taagaccata aaaataagat ttttttgttg
      181 agttatagcc aactttggct atttgattca atagttttgc ttgtctattt ctaactggtt
      241 tacataatgg actaggaaaa ctatctataa ttccgactag ttcacctttg gtgagcttct
      301 tgatgaaaaa gtatcgaata atcttgatag tgtaagctaa gtttgaactt aagcgagtga
      361 atcgactcct actaggaaag tcaccattag gaaataagac ggaacaaacc gctctatacg
      421 tggctctttg gctagtatag ccattaatta tgccccatat aacacaagca ataatcactg
      481 tatcgcgttg cttcagttga tcagtatttc ttcggttttt aatcttatct ggtacacaat
      541 tgtggtatat gttagaaaca gttctcataa tttccttgaa tgttataaaa gtatctgtat
      601 aatgttcagt atattttgat gaacgcatat gtagtcctca tttcttggga gttttgagac
      661 tactatatgc gtttttttgt tgatttacca acatgtttag acattttcct ctaggaaaaa
      721 attaactagc accacgggta aatacagtat tatttcggtt gcttgctgct tcacctagcc
      781 cttgtactcg tgtttgattg gcgacttgac caaattgatt cccgacgtct aataaaataa
      841 tagctaaaag caaaatggcc aaatggcttc cgccaaccaa taaagcaata aagcttattg
      901 tttgcataac aagtcccata tacacgattt ttctttcaga ataagaatct gccagtcgtc
      961 ccacgatagg tgcagcaact gctccagaca aaccaaaaat cgctaatatc cctgcttcga
     1021 atgttcccca attgtaggcg ggactgctga tataaaaaat caacgtagac caaaagatcg
     1081 aaaatgttcc aaacatgaaa aatccactga ctgccgcttc tcttaataga cgttgagaag
     1141 caactaaatg cggcaaactt ttaagtgaat caaggtatga aacagctgta ctactttgct
     1201 ggacagaacg cggcattttc cagtaaagca gaagtgtaag aattccgact gcacataaag
     1261 caaataaata gatcatccgc caagaaaaaa gactggcaac aataccagat accgtccgag
     1321 aaagcaaaat ccccacgagt aaaccgctaa gcaatgtacc catgaccttc cctcttgctt
     1381 ttggtcccgc tagtaccgca ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc
     1441 ctattaaaaa agaagcgcat gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca
     1501 gagagacggc agataacgct accattcgaa tgatcaattt tggacgatcc accacgtccc
     1561 ctaaaggaac taaaaacagt aaccctaacg catagcctaa ttgggtcaac atcgtcaata
     1621 tcccgactgc acttgtgcta acagataaac tagctgctac ttttgttcca atcggctgga
     1681 tgtaatacat attggcaaca acaacgccac aagtgattga taatagtaaa ataagcgaag
     1741 ttgttaaagg tgttttttca ttactcttca ttgatttccc ccatttccta tcttagttta
     1801 caacttatgg aaaagattgg aaatagaaaa atacaactat tcgccacact tattatttgt
     1861 gcttttgttt tccttgtttt ttcttgcgat ctttataaat gaagacaact aaccctacta
     1921 gcacagtaac acttgcaacc aacgtgactg cagttttgtt atatccgtga aacagagctt
     1981 ctccaccaca cgcatacaac acagacgaag ggatgactcc aatcacgatc gacaatatga
     2041 tttgctgtag aggcaatttc atcgcatctg cagcaaaatt gaccatagaa gatggaataa
     2101 ccggtatcat atagcctaac attacaccta tttttggatg tttcatttgt cggattgctt
     2161 gcacccaatg attcgtttcg gttttcttat ctaaaaattt taagcgatgc ataaggaaaa
     2221 ttgcagtgat gttaccaaga gcattaccca aaatgttgat gatcgcacct gtcagtggtc
     2281 caaagctcaa accagcaatg actccaacta ctgaagtagg aatacctgga acagcacaca
     2341 tcaccgctgt caatacgatc aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg
     2401 cgagtagctc tgccttactc gctctcggat ttaaaaataa ttggatgtct gtctgatatt
     2461 ctaaatacaa ccgatagccc actaccagta tcagaatgat tcccaacgag atcaacatca
     2521 atcggattat tttctttttc atatttcctc ctgaaaaaaa tctatattca ttaaataata
     2581 gtttaacata aaaacaaaaa agcaccgaaa tccaacatag gatctcagtg cttttaaata
     2641 gtaaaaatta tttaacagtt acagatgcgc caacttcttc aagtttagct ttcaattctt
     2701 cagcttcttc tttagatacg ccttctttaa ctggtgcagg agcgccatca actacagctt
     2761 tagcttcttt caagcctaaa ccagttgctt cacgaactgc tttgataact ttaacttttt
     2821 ggtctccagc tgcagttaat tctacagtga attctgtttg ttcttcagca gcagcagcgc
     2881 caccagcagc agctacagct acaggagcag cagcagatac gccaaattct tcttcaatag
     2941 ctttaactag gtcgttaagt tctaggatag ttgcttcttt taactcagca acgatgtttt
     3001 caatgttcaa tgccattata atttcctccg tttaattgtt cttttttatt taatgcttta
     3061 tgcggcaatt aagctgcatc tccatcttct ttgtctgcca ctgctttgac agcgtaagcc
     3121 acgttgcgga ctggcgcttg tagtacagat agcaacatag atagaagtcc ttcgcgattt
     3181 ggcaattttg ccaatgctgt gatttcttcc aatgaagaga ctttaccttc gatgataccg
     3241 cctttgattt ctaatgcttt tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg
     3301 actacatctt cgttactgaa tgcaacagct gtaggtccag tgaatacttc gtccatgcct
     3361 tcaaggccag cttttttagc tgcacgtgaa agaatagaat ttttgataac tttcatttct
     3421 acgttagcat cacgaagttg tttacgtaaa cgtgttactt catcaactgt taatccgcgg
     3481 tagtcaacga ctactactga tgcagctgct gtaaattttt cgcttacttc atcaacgatt
     3541 gctgcttttt ttgcgataat tgcttcactc atttttgagt ttcacctcct gaattttgat
     3601 ggaagagttt tttgcactga aaaggcaagt cacttttata gttactttgc tcaaccagta
     3661 ttattcatca cctattcact tcgttcatag tgattctact cgctttgctc gaaaggaaac
     3721 tcctttcgct ttgctcaacc agtattgttc atcatctctt cacttcgttc atagtgattc
     3781 acaataaaaa actctatgcc accgcagaca tagagggact attgaatata ttcaataaac
     3841 gtcctcggta ggaaattaag gcttgatgcc acctactgtc ttcggtacaa gttaattatt
     3901 aacctcaact agcttagcat gctaaactag ttgagtcaag aattattttt cagttggatc
     3961 aatcaacatt ctaatattta attagaaaga agcttggtca acatggatac caggtccaaa
     4021 tgttgttgtg atcgttacat ttttcatgta ttgaccttta gctgctgatg gtttagcttt
     4081 tagcaataca tcatggattg ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac
     4141 ttttccgatt ggtacatgga tatttccagc tttgtccaca cggtaagtta ctttaccagc
     4201 tttcacttcg tttactgctt ttgttacgtc cattgtaact gtaccagttt tagggtttgg
     4261 cattaagcct tttggtccta atactcgtcc tagacgacct acagtagcca tcatatcagg
     4321 tgttgcaaca actacatcaa agtcaaacca tccgttttgg attttttgaa ccatgtcgtc
     4381 gtcacctacg aaatctgcac cagctgcttc agcttctttt gctttgtctc ctttagcaaa
     4441 aactaaaaca gtttgtgttt taccagttcc gtttggtaat acaacagcac cacggatttg
     4501 ttggtctgct tttttagggt ctacgttcaa acggtatgca acttcaactg ttgcatcaaa
     4561 ttttgcaatg tttgtttctt ttgctaaagc tactgcttcg gcaacaggat aaactttact
     4621 tgaatcaact ttttttaatg catcttgcat ttttttgctc tttttagcca ttttggttcc
     4681 tccttgattg tggttataac ggttgtacct cccacgtgtt ctatatcttt caatatagag
     4741 ccaactgaga agctgctgtc ttagggtgta tagattattc tacagtgatc cccatgcttc
     4801 gtgcagttcc ttcaaccatg cgcattgctg cttcaacgtt agctgcgttt aggtcttcca
     4861 tttttaattc agcgatttct cttacttgat cgctagaaac tttcgcaact ttatttttgt
     4921 ttggttcgcc tgaacctttt tcgattttag ctgctttttt caatagaaca gcagctggcg
     4981 gtgtttttgt aacgaatgtg aatgaacggt cttcgtatac agaaataaca accggaatga
     5041 tcaaacctgc ttgatcagct gtacgagcgt tgaattcttt tgtgaatccc atgatattga
     5101 tacccgcttg acctagtgca ggacctactg gtggagctgg agttgcttta cctgcaggaa
     5161 tttgcaattt aacgattttt tctactttct ttgccacgag acatacctcc ttaagtccgt
     5221 gatgtggtta attggagatg catatttctc ctcccacgtt ttatctgatc tgaaaaaatc
     5281 cagacaaata atgtgcaaaa caatgcacac tggtacagta tagcaaattt atttgttttt
     5341 tcaagatttt tttctgctat ttttacattt tgcttgaata aacgctaaat ttattctaaa
     5401 aaaacaacaa tttttcgttc tcatttcttc ttttatgtta cacttgcgct agcatggttc
     5461 aacagatgaa agcaaacaat aacacggttt tttagaccct tgtacaaaga ttcctacata
     5521 acaaaatgag gtggagaaaa tgaaagattt aaggtataga agtgtctttg atattattgg
     5581 acctgtgatg attggtccaa gtagctctca cactgccgga gctgctagaa tcgggaaaat
     5641 catacgtagt atatttggcg aacagcctga ttctgtagat atttatctat atgaatcatt
     5701 tgcaaaaacc tatcgggggc acggaacaga tattgcatta gttggcggcc tgttagggat
     5761 ggaacccgat gatgaacgtt tagctgattc tttgaaattg gcatatgaag ccggtatgga
     5821 agtcttgttt gttcctaaga gtgaaaaagc cgaacatcca aactctgtaa agatgcttct
     5881 aaaaaaagga acacgaaagc tttcagtcac tggcatttcg atcggcggtg gcaatatcca
     5941 gatttctgaa ttgaatggat tcaaaatttc tttaagcatg ggtactccta ccttgatcgt
     6001 tgtccaccaa gatgttccag gtatgattgc taaagtgact agtatacttt ctgagaccaa
     6061 tacgaatatc ggcactatga cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat
     6121 aattgaagta gatgatcctc aagtagaaga aacggtaaaa agactcaaac agctgccaaa
     6181 tatcgacagc gtaaattatt tcgattaagg agctaaaaaa atgtttttat cgattgaaga
     6241 attagtagat caagcaaaag cttatccaag tgtagcagaa ttgatgattg cagttgaaat
     6301 ggaaatgagt ggccgttccc gtagtcacat catcgagatc atggaaaaaa acctctcagt
     6361 aatggaacaa tcaatcaacg agggaaaaga aggtgttacc tccgtcacag gaattaccgg
     6421 tggtgatgca aaaaaattag atgattattt aaatgaggca gactttttaa gtggagaaac
     6481 aatcttaaaa gctgtacgca atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt
     6541 gatttgtgct acaccgactg ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt
     6601 ccgagatcgg cttgatttga cacatgaaca gcaattggaa ttcttattta ccgctggcgc
     6661 tttcgggtta gtcatcgcaa acaacgcttc tatcagtggt gcagaagggg gatgtcaagc
     6721 agaagttggt tctgcaagtg caatggcagc agcagctttg gtttgtgcaa aaaatgggac
     6781 tcctcatcaa gcagcacaag cagtagccat tacattgaaa aatatgatgg gactgatttg
     6841 cgatcccgtt gcaggcttag ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc
     6901 tcaagctttt atctctgctg atatggcatt agcgggtatc gaaagtgtca ttccgccgga
     6961 tgaagtcgtt gctgcaatgt accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac
     7021 agcagaaggt ggcttagctg ttacgccaac tgctaaacga cttgcggaag agattttaaa
     7081 taagagggcg tgataaagct ccttaatttc gagtattaag agattagtta tcttcataac
     7141 aaaaaacgaa gagaggacta attgcccttc tcttcgtttt ttattaatcc atcaatttcg
     7201 tattttttac ttcatcgatc gtttttgttc ctgcaagttg catcgtgatc gacaattctt
     7261 tgttcaggtg ttcaaaaaca gatgttactc cttctgcccc acctagattc aacccataaa
     7321 tcactggtcg gccaatcgca actaagtcag caccacttgc cagagctttg aagacatgct
     7381 ctcctcgacg gacaccagag tcgaaaatca ctggtacacg tttgttgact acttcggcaa
     7441 tttttggcaa tacttcaaag gacgcaggac ctccatctag ttgacgtcca ccatgattgg
     7501 atacccagat accatctgcc cctgcagaga tagcgattac tgcatcttct ggcgattgta
     7561 ttccttttac gataactgga agatgggtga tttctttgat tgttttgatg tcatctggtg
     7621 tcaagccttg ttttgcagct gcataaattt ctgcgattcc ttttccttcg ccattaccac
     7681 ttgcactttg ttcgctatac gcagctaagt taggcattgg taatggaaat tggaattgat
     7741 tgatgacgtc ttcttcacgg taaccaccga gcgttgaatc tgccgttaaa atgatagctt
     7801 tagcccctgc ttctactgct ttgttcaaaa tgaactcatt gaatctgtcg tctttactca
     7861 tatataattg gaaaaactgc ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg
     7921 tatttgcata agtgctgatg gaaaagattg atccagcagc agctactcct ttagctgtat
     7981 cagcttcccc tttttcatgt gccaatcctt gggccgctga tggcgcttgg ataatcggtg
     8041 tatctaattc aattccgaaa acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata
     8101 tccgtggcat gattttcttt gtattaaaag aagtcgtatt ttctttcatc gtccactcat
     8161 cttcagaacc accgcgaata tagccaaaag ctcctgcttc catgcgctct tttacacgac
     8221 cttctagtta ggcaatgttt acaatatcga ttggatgttc ttcattactt gtatgataag
     8281 tcatagtaga tccttctttc atcttcttga ttacatataa atcatactaa acttacaaaa
     8341 agtaagcaaa catttactct cagatacttt tatcgctatt ctttccaaat aaatcgactt
     8401 acaagctgat ctacttcttg gttttcatga agcatactat gagaggcatt ttcacctgtc
     8461 actacttttt cctctatttc atttccgcgt tgcttcaaca acgcatagac cgctaatgca
     8521 ctgtttaacg gtactgttcc atcactcaag tctgtttcat ctagttgacc agcaatcaag
     8581 aaaaatcgag tggttatagg aatattaccg atcatttgct ggtaatcttg atagcggtta
     8641 gaaacgacag caggcccctt tgctaactca tctgtcagag actgcgcact atcatcgaca
     8701 aaatcattaa aaggcgcgcc aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc
     8761 tgtccatacg ttcctaaata gcgtagtgca ctaactcctc ccatggaatg ccccactatg
     8821 ttgactttat ctatgccgta gttttctttc agatacaaaa gacaagtttt gatccattct
     8881 gcttgattcc actcgttatt tttattatct tcaaacaata cttggaccat cggattgtct
     8941 gcttttccag acaaatctcc tgttgcttgt atttgtccat ctgttcctac tgttaaaacc
     9001 aattctttta ctgcttgctg atttttttcc aaacgccgca acatcccttt aaaggaattt
     9061 tctgtcccgc tgtagccgtg gaaaaaaagt gttggaatag tggttttttc tatcacttta
     9121 ctggattctg ccgttttttc tttatcagaa acttcagtag tatttatctt cgtcgtctgg
     9181 caaccactta acgcaaacaa actgataagg actaaagctg ctgcagttgc acgtttgcat
     9241 aaatttttga ttggttctgt catacacctc ttcctttcca tatagaaaaa agaaagactt
     9301 gaaaggccaa tcatatgatc gacatttcaa gtctctttat taatcgattt tatctacttg
     9361 atcgaaatca agttctgtac tggtttcacg tccaaacata tcgatgttga ctttcaattt
     9421 ttctttttct ccgtcaactt ctgttacttg tccttctaat ccagcaaatg cgccttcgat
     9481 gattttcacg acttcgccaa cttctacttc tagatcattt tgtcgcaggc tcataccgat
     9541 agaacgcaag atatgattga cttcttctgg aagtaatggt gctggtttgc ttccggctcc
     9601 gtgtgaacca acgaatcctg tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc
     9661 tgtcatgatc atttcaacaa gtacgtatcc tgggaatgtt ttatgaacga tttctttttc
     9721 tttcccattt ttgacttcag tttctttttc ttcaggaaca acgacacgga aaataaagtc
     9781 ggccattttc atactttgcg cacgagattc gatatttgct tttactttgt tttcatatcc
     9841 tgaatatgta tgcaagacat accagttttt ttcaaaagat tccattgaag gctcctcatt
     9901 tcattgtaaa ataaaaaaac ctcagtacac ccgaagtttt tctttcgctt cattatagca
     9961 ctaaaagtac gttgtggcta gcgagttatt ttaaaatcca gccaaataag ctttggatgg
    10021 ctgtatccat tacgtaaaac atcaatccga aaataataga agtttcgatg actactaacg
    10081 tatctttacg gagttgtttt ctgcttggcc aagttacttg tttgatttca tcttttacgc
    10141 tttttagaaa tttcatgaga caacctccct tgctactgtt tatttcgttt ctttatgtaa
    10201 tgtatattga ttacaatatt tacaaaactt attgatttcc aaacgttcgc cgctttttcc
    10261 ttcactgact gattttgtgt agttgcgaga cccacaaacg gaacaagcga gtgctgcttt
    10321 tttctttgcc atttacttct gcccccttgc tgagaatcag acttatactt cataacagta
    10381 tcacgtaact ttttacttgt caatttgtga aataaactat ctattgtttt ggataaaatt
    10441 atgatatgat taatttgaaa ttaagctaaa atgagacaat tggaggtata gcgatgctat
    10501 taaaaacact tgtatataag aaaaaagatc tgacaaccgt tacagagact agtacattag
    10561 aagaagcatt aaaaatttta gaaacttccg gataccgttg tgtgccgatc ttagattctt
    10621 caggtaatat tttccgtgga aacatttaca aaatgcatat ctatcgtcat aaagcaaatg
    10681 gcggtgatat gacgcttcct gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc
    10741 tggatacttc tttcttcaaa gtattcttta cgatcaaaga gcttccttat attgctgtcc
    10801 ttgacagtga aaatcatttt tatggtattt tgacacatag tacgttgctt aatatgctct
    10861 ctcaatcttg gagcgtagaa caaggaagct atgtactgac aattgcttcc acaggaaagc
    10921 aaggagattt ggctgctatt gcaaaaatca tttcaaaaca cagcagcatt gccagctgta
    10981 ttactcttga tatcgaaaaa gacgaataca ttcgacgtac attgatcacg ctaccggcta
    11041 acactgaagc gaaagtatgt gaaacgatcg tcaaccactt agagaaaaag aattataaag
    11101 tggtagaaat tgaaaatttg caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac
    11161 agctaatctg ctttcttttt tcgcttttta taattagaca cgcttttcaa aatcaagcgc
    11221 gcgatctaaa taatacatca atggtgctga aacagccatg acgataaact cacttaatgc
    11281 aagcgtgcca taggttgtcc aaaatgcttg gccacctgtt ggaactaaca tataagcaat
    11341 cagtcccatg ctgatggtaa agaagatcgt gttcaatact aaacgcatct ttacattttt
    11401 cactttgttt tgcaataaag ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa
    11461 aaccacatcc atgataccaa aaccaaagaa ggcattatag acgatgaccc cgcctaaaac
    11521 tccccaaagc aatttacggt taaagacaac taaatgattc aaactttctg aaatacgaaa
    11581 ctggatcggc cctgaggata caggcgcaac taaaatagtt aacgctagat aaagagccat
    11641 gatgatgcca tttacaacga ttacggataa ccgttgtctg cttttcgttt tttgcatttt
    11701 ctctcctctt ttctcctagt ttttttaacg cgggatggtt gatgaaccgc ggttatgtga
    11761 aacaaacaat aattataaca gacttttcat ttatttcaat ccgtcttatc tgcttttaaa
    11821 aaagcaaaag cttaaacaat gtaaacgttt gctaaaaatc gtgggatatg gtataaagta
    11881 agtgtaaggg gtcataagaa ttcccagtaa agcagacgaa gtaggatctg caagaacaga
    11941 attgttgtga aacttaaata aataaaaaag gatgtgggaa tttgagcaac ctcttactag
    12001 agaacggtct agcaagcagc tgaagatcta agtggacatg ccgaaccttg gaacttctcc
    12061 ttacgtaagt aatggatcat gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc
    12121 tttttcattt tcctagactt ctgctataat aaccaagaat taattttgta acagattttt
    12181 ttgaaaaaac aagtttcttt cattcaaaaa atagaaaaag cttgctaatt attggttaac
    12241 cagcaaacag gagtattaaa atatcttgtt ttattgaata gcaggaggaa atcatgaaat
    12301 tccattatca tatattgatc aatccatcgg caggcagcgg aaatggctat aaagtagcag
    12361 aaagaatttt accggtatta aaaaataagc atattgacta tacacttcat tatagtgaat
    12421 acaaaggaca cgatgctgag attgctgaaa ctttggcaaa agaaacattg attccttgga
    12481 tagaagaaga acagaaaaca atcgatactt tccccctttt gatcatcgta ggaggtgacg
    12541 gcaccttaca tcaggtactt gatactttct atcagatgga agtagaattc ccagttgctt
    12601 atattccagc aggttctgga aatgattttg ctcgaggggc aggccttcca aaaaatccca
    12661 aaaaaggact tcagctgatt ttagcagctc aatcaccaga aaaagtccac ataatggctt
    12721 atgaagaaaa aataagtgaa aaaaaaggaa tagctgttaa taatttcggt ataggattag
    12781 atgcagctat cgtccatgcg acaaatcatt cttccacaaa aaagcgattg aacaaataca
    12841 acttaggatc attttcgtat ttattctcta ttctccgtgc tttattcact caaaaaggat
    12901 ttccaattct ggtagatgca ggaggaaaac aattaagttt ttcaaacgca tttttatgta
    12961 cagcaacgaa gcatcctttt tttggcggag gaatcgcgat tgttccaact gctgatgcgt
    13021 ctaaaccagt cattgatttt gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc
    13081 tcattctttt acttatacag aaaaaacaat tgaaatcgaa atatttccat cactacacaa
    13141 caaacagatt acgtatcgtt tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa
    13201 tggaaaaacg accttttgat atcacaataa ccacaactaa acagttgttt tggtgttaat
    13261 aaaagaggtt ttgtcagaag ctacatctgg aacaccgttt attcggaaaa aaggactgtg
    13321 acacgacttt tgtcacagtc ctttttttac tatgcagtta attctttgcc caattgggtt
    13381 gccatcgata gtttctttct ttacccaaaa taaattggat cattgaaaac accgcagcaa
    13441 aagcaactaa gacacaacca ttgaaccaaa aagattctgc aaatgtttga ttgtaactga
    13501 gtgtttcact gatcaagtta ttattttgaa caaaccaata tgttggtgtg aatgccgcta
    13561 ttttgctaac catttctggc aagtattctg ctggtacaaa caccccaccg ataaagcaac
    13621 tgcctgtgat aaaaatatct ttgatcccac cgctggtttc tgagtttttt accaatgaag
    13681 tgatacaagc cgaaaagcta atgatcggca ataaaaacaa gaaagtattt aaaatatgat
    13741 accataccgt tatatcccac gaggtgtgga tcactaacag aaccattaga agtaagaagc
    13801 cactgaacaa cagcagcgag taactaatca aactaaaggt tactttgcga ttcaagtttc
    13861 gtttggtaat gggcgcactc tggtttcgtt tactgatctc tttgcgatta aacgctagat
    13921 tgatgacgct gaaaccgcta aaaatggata gaaacaaccc ataagacaag aaattaaagg
    13981 ttgtgcccgt caacagcttt ttcatccgct gactatatcc cgcacttagc tcaacttctc
    14041 cagtaaccga gagtgccatt tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt
    14101 cttgaaacag aatcagtgtt tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag
    14161 aaaaggcatc tgggcgactc tgtatcttga tcgtcgccat ctttcctact tcgacttgtt
    14221 cggtaaagtc tgcaggcaga tgtaagataa tgtttacacg attaaaataa agagcatcat
    14281 cgatttcttt ttgtgaggtt ccatccaatg taacgactgt ttccttgtca ttcaaatatt
    14341 tacgaaggcc atcgactaca ggcgactctt cttcactaat caaggcgatt ttcgcatctt
    14401 gcagagaggt attttcaaca tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga
    14461 taattacacc tatcagtaaa ttcgatttat ttgctttaag caatgtccaa atcgttttat
    14521 aaagcgtcat aacgcacccc tctttccatc caagcatttc ctaacgcaaa aaggaaaata
    14581 aatccgatca accatagaag attggtataa aaactagcca aatcagtgta gaaataaagt
    14641 ttatacaaac tttcgctgat caagttgacg agatttaatt gaccaacaat cggaatatga
    14701 agatcaatcc aatacttcac ttgttccgac cccatcatac cagcaaaaaa gctcatcgca
    14761 atcgtcactg aaatcaagat gctatccttt tgcaccagat tcatttttgg tatcaaatta
    14821 ccaaccaatg tacctaacaa aatcgcacac aacgacccca gagcggtaac aatcatcaac
    14881 cattgccaac gttcaccaaa gtctacttga tagataaaac gaaagacagc taacataata
    14941 taaatctctg tcaaaacaat cgtaaagctt gctgccaaat tagcgattga aactaacgat
    15001 tgctttctag gaatcaagga caagcgaata ccatttgacg attgatttgc ttgctgatcc
    15061 tgtacattgc ggacccccca catcgtcccg tagagaatcg ccattccaat cagagtgaag
    15121 aaataaaaac ttttgaaact catattacga cctgcatgaa cttcttgaaa agatacttct
    15181 tgttcaaaaa cagtcatgat gggcgcgaga tcaacgttct ccacttctgc cactttactc
    15241 gaaattatac caatacgctg taaaaattga tccatgacgt ttttcatcaa cgtctgactc
    15301 attcctgctt gacccacatg gagcgaaaca gatgaaccat caatgagata aaaaccagcc
    15361 aaatcatctg catttagctt ttcattcgct tctacttccg atagttcctg tacttcaaat
    15421 aatggtttat cattgacttc gacttgttct aagactgtgg taaaattttc cgaaagcgct
    15481 gtttgatccg ctttgattac aattccagta ttaatcgttt caagattgcc accttgatca
    15541 atctcgccaa aggccgccat aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa
    15601 aacaacatgg atttatttcg cagcagtatt tttgtgcgat atttataaaa atgccaaaac
    15661 attatttccc ctcctctagt ctctcaaatc cttgccagta atctctaaaa agacatcatt
    15721 caaggacgct tctttggttg ctatttttcc gtaactgatc ttttcttctt gtaagattgt
    15781 aagaatcggc aacaatactg tatttagttc agtagttgtt acttggagct gacctttttt
    15841 ataagcgatt ccatcagaag ctattgttcg ctgaatcgct gacaacacat tttctgggag
    15901 taatgggatg tcgatcgtca aacgatccgc cgtccgtacc atatctttta gagattcttt
    15961 ggttccttta gcaatcacct gtccttgatc catgatcacg atctggtcgc aaagaatttc
    16021 tacttcttcc atgtaatgtg ttgtatagac aatggttgct ccttgtcgat tcagctcctt
    16081 gatactttct aaaattttat tccgactttg ggggtctaca gctactgtcg gctcatctaa
    16141 aaaaattaac cgcggcttgt gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc
    16201 accactaagt tctcctggac gaaacgaaac atatttttct aatcccacta attgaatcac
    16261 ctcttcaatc aaggctttcc ttttctcttt ttcggaaaca tataaaccgc aaaaataatc
    16321 gatattttct tgcacactta gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat
    16381 cattgccttg acagcataat tttcaggagt cattgttgtc ccgaacaatt taatggttcc
    16441 tttgtcataa tttaacaaag aaagcataca gttgatggca gtcgatttcc cactgccgtt
    16501 tggacctaac agacctaaga cttctccttc ttgtacttgc agatcaaaat gattcaatgc
    16561 tacaaaatct ccatagcgtt tgactaattt atcaatttcg ataatcatca tgaaaaactc
    16621 cttccaaatt tcttgttgat ctgactataa taaagtgcaa gaaaagaaac tagtgacgat
    16681 tggctaaacc acacatgaca tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc
    16741 tactcaacga aactagcttt ctactggtta tctcattgct tttgctggta agtcaaggat
    16801 tcgttgctat gcaagttatc tatttattga tcgccgtttt attcactggt gtcagttatt
    16861 tactgcctac aaagccaaat tggattttcc aagttattct atttctttta tgtgcctttt
    16921 tacctgatct tgtcctgttt ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc
    16981 accttgatta cttgtttttg ttaggttttt tgttgatttc gacggttggt aatcatcccc
    17041 ccatcaaggt cgcctttgtc gtaattttgc tgtttttttc cttttactta cgaaaaaaag
    17101 atcaacgaac gaccgatctt gagaaaaagt acattgtctc caaagatact cattgggaaa
    17161 aacaacaaga gttatcggaa caaaataaag cattggccct gtcacaagaa acacaattag
    17221 ccttgcaaat tgtggaagaa cggaaccgaa ttgcccgaga catccatgac aatgtcggtc
    17281 atctgctgtc aagtgcgatt ttacaaattg gtgcgcttga aatgatcaat caagaaccaa
    17341 aactaaaaga accattagaa aatttaagtg ccaccgttca cactgggatg gatcggattc
    17401 gtcaaagtgt ccatgacctc catgagacat cgatctcttt tcaacactcc ttagagtttc
    17461 tgatcgctga ttttccttct tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg
    17521 aaacgcagca aaactgcttc ttaatggtca tcaaagaagc cttaaccaac agtatcaaac
    17581 atagtcatgc caaaaccgtt gttttacatt ttcgaacgtt gccggccttt tatcgcttgc
    17641 aaatcacgaa tgatggcacc agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa
    17701 cgatgcgtca acgtgttcaa gaacaaaagg gacaagtcca tattttccaa gaaaaccagc
    17761 aatttcagtt aacgatcatt ttaccaaggg agggacacca atgataacag tagtcattat
    17821 tgatgatgat ccatttgtga cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat
    17881 ccgtgtgtta ggcattggtc attgtgccaa ggatgcgcga aacccatcgt cccgatgttt
    17941 tgctgacgga catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg
    18001 ctaaatttcc caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc
    18061 gcgaagcatt ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta
    18121 ttccttctgt caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga
    18181 ctttcactca aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta
    18241 gtgaacgtga gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg
    18301 cagatgcctt gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa
    18361 agctagattt acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag
    18421 tcttatctaa cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac
    18481 atcttctatt caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc
    18541 agggctgcca ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc
    18601 taacgttttt tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt
    18661 caatttgaat tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc
    18721 taatttcgct aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt
    18781 cagcttagca tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc
    18841 tatttctcat ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt
    18901 ttccatacca atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa
    18961 atctttagaa acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa
    19021 cagatctggt tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc
    19081 ttctacaggt agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa
    19141 tggatcattt ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt
    19201 cattttatca ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt
    19261 cgctacacaa gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg
    19321 agtcactgcc gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg
    19381 caaaataacc atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag
    19441 agtgatttta ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac
    19501 taattcatcc actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat
    19561 atctccattg aatacattca attcgggagt attgactaat tggaggactt tgtctcctat
    19621 ccgataaacg gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat
    19681 ctcctgcatc attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa
    19741 tacttggata tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat
    19801 caagggttca atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt
    19861 gaaatctttt ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc
    19921 atcaccttgc cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag
    19981 atcatggagt acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat
    20041 aacttgcata ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat
    20101 agacatctca tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt
    20161 tttttcccgt ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt
    20221 ttcgttcatt cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc
    20281 ttgggtatat tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat
    20341 tccgttgatc acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga
    20401 acggattgct tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt
    20461 ttcgatacgc cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg
    20521 actgagaagg cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc
    20581 gtaaagatta gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt
    20641 agcaacctga tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg
    20701 ctgaagcaat gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat
    20761 ctgatgcaag atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc
    20821 ggctagatta tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg
    20881 attttcttcg atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa
    20941 ctgactaccg aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag
    21001 ccgaatcgtc tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa
    21061 taccgaagga tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt
    21121 ttctgctgtt ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc
    21181 atttgcagtt gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt
    21241 aggatgatcc actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa
    21301 acttccggtg actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac
    21361 caaaagcact ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac
    21421 gaaataaggc atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt
    21481 ctggtgctgt ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca
    21541 ataatctgca aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca
    21601 tttcacgcaa ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag
    21661 ctccatgtcc tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa
    21721 cagtttcgat acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat
    21781 acagatctaa atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat
    21841 cgatcgactg accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa
    21901 tctctaccgg acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg
    21961 ctgtactgga ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga
    22021 tttcttcgta actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt
    22081 cctgattcca ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc
    22141 tgtctttctt ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt
    22201 gatgcgtcaa ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg
    22261 cagctgtatt cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac
    22321 acttttcttc gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata
    22381 aaaagaagtg ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt
    22441 ttgagatcaa atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt
    22501 ggtaagtaat atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat
    22561 cagttgaaaa acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac
    22621 gggcaatatt tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca
    22681 ggatcattcc tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa
    22741 aaaaaaacgt atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct
    22801 cactaacttt tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta
    22861 atataacacc ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt
    22921 tttctcttag ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta
    22981 tataagtctg ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga
    23041 tctttttgat tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat
    23101 ttcattgctt cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt
    23161 tgattcggat aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc
    23221 aacacttctc catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag
    23281 atatttaaaa ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca
    23341 caccaaaatg cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca
    23401 aatccaacag cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct
    23461 ccgcagccaa catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata
    23521 acgggctgat acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg
    23581 tattctgttt taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa
    23641 cggtgattat ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc
    23701 ggacagcgga acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt
    23761 aacatagttc cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc
    23821 taaaaatatg atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca
    23881 aagaattttg cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc
    23941 ggatcgaatt gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg
    24001 aagaaacgtt aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta
    24061 gagggggcga cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg
    24121 aagcaaagaa attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc
    24181 tagacgaaga ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc
    24241 atatggcttt tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag
    24301 aacatggtgt tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa
    24361 atttcccacg gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg
    24421 gtggtggtgt cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag
    24481 tacacggaac caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca
    24541 acaggcataa tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa
    24601 agaagcaata ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg
    24661 accgcttgct actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc
    24721 tgcaagattc gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat
    24781 aaaattatgt ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt
    24841 gacaacgccg gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc
    24901 agaaatcgca agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt
    24961 tcctgtaatc agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata
    25021 gtgactgatt aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa
    25081 acgtcgagac gctgccttta ctggattttc attaatttct tccacattga ccccggcaag
    25141 tcctgaataa tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac
    25201 gattcctaac aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct
    25261 aaatgtttgt gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct
    25321 catcagatca gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac
    25381 ccctactagc tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc
    25441 tgcttcgttc ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac
    25501 aaattcagtt gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat
    25561 ttcactggca tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag
    25621 cgtattaagc aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata
    25681 gctaggacgc atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc
    25741 gaacatatcc gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc
    25801 tgtaagagat tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct
    25861 gaatgcctga atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa
    25921 ttcttgattt tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact
    25981 gcctccatgt ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg
    26041 taaaaacgca gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg
    26101 ccatacatat catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga
    26161 tgtgtccttc ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct
    26221 atccagtact cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa
    26281 gaataatctc gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt
    26341 ccactgacta aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat
    26401 tttgcgtgcg caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt
    26461 cgcgtcacca catggattac ttggttttcg taaccttgtt ttttataata agcctttaca
    26521 cgattagcca ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt
    26581 ttatttacta ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa
    26641 agtacggttt catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct
    26701 agagaaaaca agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt
    26761 attttcgcta acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga
    26821 gaatgatctt tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc
    26881 tttcacacga tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc
    26941 tattcgataa taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac
    27001 aagataatct tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat
    27061 cggagaaccc aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa
    27121 ggcattgata ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc
    27181 agtaggcgta gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat
    27241 gtatacatcg gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa
    27301 aaaatgctgg tccggtgttt catccaaata actgatccga acatccagca agggataact
    27361 aacactttgt tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg
    27421 ccaatccgtg taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag
    27481 acaatgactg tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac
    27541 caattctggc tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg
    27601 ttctgtcact tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg
    27661 cctcctctct ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc
    27721 ctcttccatg ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct
    27781 cttcatccaa ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg
    27841 gaaaaacgcc ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg
    27901 caagagtccg aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag
    27961 gatactcgat caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat
    28021 ctcgttcttg gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga
    28081 tatcttctac aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta
    28141 aacgtcccat tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga
    28201 ctctcccagt gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga
    28261 tcccccgcag tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt
    28321 cccaatctcg ttccatagct gatacctcta cttcattaac attcattgtt tattctacca
    28381 tatatgcaaa gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc
    28441 aaaatagaca aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta
    28501 tgctgacaaa gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt
    28561 tccgtgtaca gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt
    28621 gtggcctacg gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg
    28681 aaaaagggcg tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct
    28741 tcgaaaaacg tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg
    28801 atcctgcttc attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg
    28861 aagaaggact tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg
    28921 aactagaggt aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt
    28981 tttctttacc ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt
    29041 agaaaccttt cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt
    29101 ataggatgtg aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata
    29161 tgatcgaaat ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac
    29221 agttattaca atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc
    29281 gctttcttcc tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt
    29341 ctcagaacaa tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg
    29401 actgcaaagc ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc
    29461 aagaagcagt cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg
    29521 aagaaatcgg cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag
    29581 aagtattctt ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg
    29641 cagtcgttta caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta
    29701 caagtagcct ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt
    29761 ttaatggtga acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac
    29821 acttgctttc taattaa
//
LOCUS       DADVXV010000030        29096 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.030, whole genome shotgun sequence.
ACCESSION   DADVXV010000030 DADVXV010000000
VERSION     DADVXV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.030"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            278..1063
                     /locus_tag="KB969_001245"
     CDS             278..1063
                     /locus_tag="KB969_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6869246.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            1076..1927
                     /locus_tag="KB969_001246"
     CDS             1076..1927
                     /locus_tag="KB969_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBB6869247.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(2051..2503)
                     /locus_tag="KB969_001247"
     CDS             complement(2051..2503)
                     /locus_tag="KB969_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869248.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(2968..3336)
                     /locus_tag="KB969_001248"
     CDS             complement(2968..3336)
                     /locus_tag="KB969_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBB6869249.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            3486..3968
                     /locus_tag="KB969_001249"
     CDS             3486..3968
                     /locus_tag="KB969_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBB6869250.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            4005..5015
                     /locus_tag="KB969_001250"
     CDS             4005..5015
                     /locus_tag="KB969_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBB6869251.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(5130..5843)
                     /locus_tag="KB969_001251"
     CDS             complement(5130..5843)
                     /locus_tag="KB969_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869252.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(6033..6623)
                     /locus_tag="KB969_001252"
     CDS             complement(6033..6623)
                     /locus_tag="KB969_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBB6869253.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            7107..7334
                     /locus_tag="KB969_001253"
     CDS             7107..7334
                     /locus_tag="KB969_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBB6869254.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            7350..8516
                     /locus_tag="KB969_001254"
     CDS             7350..8516
                     /locus_tag="KB969_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBB6869255.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            8750..9793
                     /gene="hrcA"
                     /locus_tag="KB969_001255"
     CDS             8750..9793
                     /gene="hrcA"
                     /locus_tag="KB969_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBB6869256.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            9887..10450
                     /gene="grpE"
                     /locus_tag="KB969_001256"
     CDS             9887..10450
                     /gene="grpE"
                     /locus_tag="KB969_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBB6869257.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            10501..12330
                     /gene="dnaK"
                     /locus_tag="KB969_001257"
     CDS             10501..12330
                     /gene="dnaK"
                     /locus_tag="KB969_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBB6869258.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            12481..13647
                     /gene="dnaJ"
                     /locus_tag="KB969_001258"
     CDS             12481..13647
                     /gene="dnaJ"
                     /locus_tag="KB969_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBB6869259.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(13729..14394)
                     /locus_tag="KB969_001259"
     CDS             complement(13729..14394)
                     /locus_tag="KB969_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869260.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            14370..14543
                     /locus_tag="KB969_001260"
     CDS             14370..14543
                     /locus_tag="KB969_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869261.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(14588..15325)
                     /locus_tag="KB969_001261"
     CDS             complement(14588..15325)
                     /locus_tag="KB969_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6869262.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(15327..16829)
                     /locus_tag="KB969_001262"
     CDS             complement(15327..16829)
                     /locus_tag="KB969_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBB6869263.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            17088..19082
                     /gene="uvrB"
                     /locus_tag="KB969_001263"
     CDS             17088..19082
                     /gene="uvrB"
                     /locus_tag="KB969_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBB6869264.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            19092..21908
                     /gene="uvrA"
                     /locus_tag="KB969_001264"
     CDS             19092..21908
                     /gene="uvrA"
                     /locus_tag="KB969_001264"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBB6869265.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            22171..23436
                     /locus_tag="KB969_001265"
     CDS             22171..23436
                     /locus_tag="KB969_001265"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBB6869266.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            23440..24171
                     /locus_tag="KB969_001266"
     CDS             23440..24171
                     /locus_tag="KB969_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBB6869267.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            24306..25190
                     /gene="rapZ"
                     /locus_tag="KB969_001267"
     CDS             24306..25190
                     /gene="rapZ"
                     /locus_tag="KB969_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBB6869268.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            25187..26185
                     /locus_tag="KB969_001268"
     CDS             25187..26185
                     /locus_tag="KB969_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBB6869269.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            26219..27154
                     /gene="whiA"
                     /locus_tag="KB969_001269"
     CDS             26219..27154
                     /gene="whiA"
                     /locus_tag="KB969_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBB6869270.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            27697..28347
                     /locus_tag="KB969_001270"
     CDS             27697..28347
                     /locus_tag="KB969_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869271.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            28534..>29096
                     /locus_tag="KB969_001271"
     CDS             28534..>29096
                     /locus_tag="KB969_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBB6869272.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT         9565 a         4897 c         6176 g         8458 t
ORIGIN      
        1 aaggggctgt gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa
       61 gtagcttctt cggaaataag ccgaaatttc ttgaagctga ccacttctgt cacaacctct
      121 ttctttatag aaataaaagg acactagcaa ttcatgaaaa cgattgctag agcgtatcat
      181 ttgctttaga ctatatatct tggtgtacac tcactttaag gcggaaataa aagttatccg
      241 taataacagg tttaggtatg aaaaaggagt gggtactatg tacaaggaat tagaaaacaa
      301 agtcgcagta gtaactggtg gctcaaaggg gattggaaca gcgattgctc aacgattcgg
      361 gaaagaaaaa atgaatgtag ttgtcaacta taactcggat aaagaaggag cagaaaaagc
      421 agtcaaagca atcgaagagg caggcggaaa agcagtctct gtacaagcag atgtcagttc
      481 tgaagaagga atacagcgtt tacttgatac ggctttagaa aattttggga cactggacgt
      541 ttgggttaat aatgctggga tggaaaatca gcatccaacc catgaactta gccttgaaga
      601 ttgggaaaga gtgttaaaag tcaatttgac tggcgttttt atcggaacga aagcggcttt
      661 aaattacttt acagagaata ataaaaaagg aaatatcatc aatatgtctt ctgttcatga
      721 acagatccca tggccaacgt ttgctcatta cgctgcttca aaaggcgggg taaaattatt
      781 taccgaaacg gtagcaatgg agtatgcacc gaagggaatc agaatcaata gtataggccc
      841 tggtgctatc cgtacaccta ttaatgcggc aaaatttgat gatcctgaac aaaaagaact
      901 cttggaaagt atgatcccac taggacgcgt aggtgaacca aaagaaatag cggcgacagc
      961 tgcatggttg gcttcagacg aatccagtta tgttacaggt attacactat ttgcagatgg
     1021 tgggatgact ttatatcctt ctttccaagg tggaaaagga taagggtgaa taaaaatggg
     1081 tttattgatt gcattgatcc cggcagttgg ctgggggatc cagccactga ttttgaaaaa
     1141 gattggtggc agaccaacaa atgagatatt aggaactggt attggagcgg tgcttgtcgg
     1201 cttactcgtt caattattcg cttctccagc tggtatttca gtgactacat ttttgattag
     1261 tttactttct ggtgcatttt gggttattgg acaaacagga cagtatacat ctttcaactt
     1321 gattggtgtt tctaaaacga tgccaatttc gactgcatta cagttagtcg gaacctcgtt
     1381 gattggtgtc ttcgcttttg gagaatggtc tggaagtatg gggaaaatca ttggagcagc
     1441 agcaatcatt cttcttgtat ttggttctgc tttaacggca atcagtgatg atcctggaaa
     1501 aaaaggcggt atcacaaaag gaattagtct attagcatca acaagtattg gttattgggt
     1561 atacagtgca ttgcctaaac tagttgatgc aagcggactt tccattttct ttccgcaaat
     1621 gatcggtgtc tttttagggg cagtgattta tgtgattttc cgtaaaccaa ccgcattttc
     1681 tgaagacaag agttggaaag caacgatcgt tggagccatc tttagtgtgt cagcattggc
     1741 ttatattttt tcagcaaatg aaaatggggt tgctactgca tatatcatta cacagctaaa
     1801 cgtagttatc tctacattag gcggtatgta catcctgcat gaaaataaga caccaaaaga
     1861 aaaaaaatta acgattatcg gattattgct gatcgtagta ggaagcatgg tcacggtctt
     1921 tatttgagga taaagatggt aaaatttcat ttattaaaaa aatatttgtt tgaaccaaac
     1981 agtaagtact tataaaaaaa tagcgctaga atttccaaca tctctggaat ttctagcgct
     2041 ttttaattgt ttaagataca agggaaatat ctgtctggat caataatttt tcattgatcc
     2101 attgactaaa gtttacgaca taattgaagt taccaccgat tagtatctcc gcatgattgt
     2161 ctttataaag atcgtattgt aaaagacggt cttttttatt tgcgtaaaca tcgttatggt
     2221 actggactaa ttgttctcgg aattgattga ttgctgtaaa atcacgatat tgaaggttga
     2281 aacgcatcgt gattggtgca tttagcatga atcgctgcat ttcttttgct gcttcctctg
     2341 cttgatctcc gtataggaac tcaaaaagat tacgttcaga aaatttccat tgcccgccaa
     2401 cctttgttcc ttttagtttt ccttcatgaa gataatttct gatagaacgt gtagtaacac
     2461 ctaattgttc ggctaattca tttactgagt aaaaatcttt caatgttcac cctcctatgt
     2521 gaatggttct actgacttag ttgatatttg cttaatcacg aaatgtagaa agaacgattt
     2581 taattaaggt cattgtaaaa atcaagtcag aaaattctaa cttttatttc tctaaagaaa
     2641 ttcgttctct cctaaagtga tattatattt aaatatacct gaaaataatg ggcagtatta
     2701 tgaaagatca ctgatatttt ctcgtatttt ttccttattc aaaagttttg caggaaaatt
     2761 gctgaaaaaa taattttact aagtagaaaa ttcaaagcca ttcaatcagt gatttttttc
     2821 agcacaagaa agactcctta taaaaatagc agatactttg tcaattaagt gtttaaccag
     2881 ggatgataaa aaggatagga ttgaacaaaa cctgtataag gtgatgaata gtttcctcgc
     2941 cagtaaaagg tttattcgta taaagcttta tcgccaaaat ttatcatgac cttttttatc
     3001 ttcaatatta aatgaaatca attgttcaat caattcccag ttgattacac ttttccaagg
     3061 aactttgatg acgttatccg tatatacgta gcctgcttct tggatatttt tttcaagggc
     3121 acgaatcgct gctttttccg gtgcgataga aaaatgattt ttagcaaaac taaatgcaat
     3181 aataaaggta ccatggtcag taaacatagg ttggttccat tttacagttg tgtctagctg
     3241 gggatacgtt tctgttatct tagcaaaaag gtctttgatc ttttgttgat gttctttttc
     3301 tttgatttga ttgatgatcg gctgaaattt ttccattcta aaacgcctcc attaagtggt
     3361 ttgatttatt ttaccagaaa aacaatagtt atgtataaaa aacgaacaaa acacaagtaa
     3421 tgttgtaacc gctatattta tatgataaga tgtctcaaat aataaaatag aaaagagaca
     3481 taaaaatgat tgacttggca aagaaattct tacacgaaaa tatatatttt gagttgtatc
     3541 atcatcgagc catttataca aatgaagatg ctttggtaat aaagaaagaa caaggattta
     3601 caggtacaga gaccaaaagc ttattcttaa aagataaaaa agataataac tacgtatatc
     3661 tgacttttac tacgaaacaa acggatttca aagcattagg gaagatcgtc ggtaaaaggc
     3721 tttctattgt ttcatcagaa cgcatggaag aacaaacggg acaaaagcag ggcgctgttt
     3781 ctccgtttgg ttatgaaaaa cagattccga ttattattga tgaagagctc ttatcaaatg
     3841 aaaaacttgt ttttgcacca ggtagaccag atcaaacgat ggtcatccaa acggttgact
     3901 taaacaaaat catccagcta cttgagatgc cgatattttt gatgccggca aacgaaaaaa
     3961 acaattaacc aagtaaaata gtgcatactt ggaggtgaag caacatgata agttatccat
     4021 tattagaaag aaatgcaacg attggggtta ctgcaccatc ctcaggcgta tcagaggaac
     4081 accattcgtt actcgaatca gctttaaaga gaatggaaga aaaatctttc caagtagtta
     4141 ctggaaagac gctttggacg caagataagg aaaaatcagg tccagcaaga aaacgagcag
     4201 atgaattcaa tcaaatgatg caagatgaaa atatccaaat gatctttccg acttggggag
     4261 gagaattatt gattgagatt ctcgattttg tcgattttga tgctctacaa ccaaaatgga
     4321 tagtaggtta ttcagatatt agtacgttgc tacttgctgt cacattaaaa acagggatag
     4381 ccactgcaca tggaactaac cttattgatt taagaggaga gtacttggat gaaacgacag
     4441 caatgtggga aagtgtactg aaaacaagag aaggagaatc gattctacag caatcttctg
     4501 aaaagtatca aaaagtgtgg ccccatgagc attcatcatc ttctgttttc catctcactg
     4561 aaccaacaaa ttggcaatca gtcagcggag atgcagtaag gatgaaggga cgattattag
     4621 gtggttgtat tgatacgatc aggcatttaa tcggtactcc ttatggagat gtccaatctt
     4681 ttaaaagaaa gtataatgat ggaaagccga tcttgtggtt tctagaaaac tgtgagctat
     4741 cgtcagttga tttaagaaga tcacttgttc agatgaaact ggcaggctgg tttgatggca
     4801 gctcggggat catgttcggt agaagtgcgg cagaggattt gttagattat aaaatgaagg
     4861 atgtatacga agatctgtca aaggaattaa aactaccgat cttgtatgat attgattgtg
     4921 gtcatgtacc gccacaactg acattgatta atggtgccta tgcagaagta gcggtagaag
     4981 atagaaaagc gactgttttg caaacgttta tttaaaaaat tttttcctgc cttggagtct
     5041 atcaaagacc aataaatcta aatagaaaag aaagtgaaag aagctgacaa aatgctgtca
     5101 gcttcttttt gtataacata ttagaaagtc taattatcta taactgtcac atcgattaac
     5161 tgtttcacgt cattgggatt tcctgtagga atagctacta cagatgcatt atcaatgatt
     5221 tcttgagttg tttctctaat gaacgctgga taagatgttt gatctgcagg catttgccaa
     5281 tgtgaaggaa ctggataact agtgattgtc ccgtcatggt tacttgaata cactaaaact
     5341 ccctggtaac tgtatttccc agtgagcata accacatctt tcggatagac tgcactccct
     5401 gcatcataag gggcgatagg tgttcctgca ggataatgaa taacatgtaa ttcgaaatca
     5461 cccgatgtat ctctaaaagt attacctcta atagctagcc aaacacgtgc gtactcaatt
     5521 tgtagatcag aatatcctgc taacggatct attgactgag aagactgtga ggaggttgtg
     5581 tctattgttg aagaagaaat atttgtctca actgtactac tagatgtaga agaagtattg
     5641 ggctctgaga ctttactgct tgttgaagat gtattcgttt cagtagaagc tgatttctga
     5701 gtacttgatt tttcagctga actggtttgt ctgattgaac ttttgtctgt ggtcgcagat
     5761 ggatcactat tttctttact aggagacgta catcctacaa ggaataaaga gaccaacaat
     5821 aaaataaaac ctaacttttt catataaaat acctcattat ttttttaata ccagtatagc
     5881 ataatcctga atttttgaat ccgtaaaacc ttgtctatga atataaatag agtgtatctt
     5941 ctttgataaa tgtcagaaaa agtgtgacaa ataatcatca gtaaaattac ttgtcacact
     6001 attgataagg agtatttaat tgaagagaat gattaggaga aaggatctcc gtacttttta
     6061 tagtaatcat agaatccaag tttgtataga cgaatcgttt tttctcttat ttcttctgtt
     6121 tcaaaatgga ctgcttgaag aatcaagtct gtgaattcta taggagctgt tccattcgca
     6181 gtaatcaaat tacgatcttt cacagcttgt tgttctataa aatcttcttt attctgataa
     6241 ttttccgatt ctaaccaagg aaattgcgca tttccggtgt gtttgtaacc ttgcaataat
     6301 ccgctctgag ctaaataatc aactgcccca caaatagcag ctactggtac gtctgttttt
     6361 aacaatttat cgattatttg atataaatga tgatttttta tgtcccatga attgccaccg
     6421 atcataataa aaaggtcaac tttttcaggt atttgttcga ttaagtaatc gatttttgtt
     6481 tttaatcctc caatggaagt gacctctgat tggatagaag cagttttgtt ttgccatttc
     6541 tcattttggt ttagtgtgct agtaatataa gcaccttccc aatcggcata ttcctctaat
     6601 agaaacgtaa tcgcagtttt cattttcaag ctctccttta ctatctataa caaggacaac
     6661 agttttaacc tacagacatt cattaaaatt gggtagcgac agcgaaaaca acaattctta
     6721 agttttagac agagtataca gatagtcaac ttaattaaat acgaactaaa taaaaatgac
     6781 aggtaatcat ttttgtttac cagcattata acattttgca tacatggatg acaaaagaac
     6841 caattcccac ttgcttgagt acaatattaa aagaaactgg aaggcaaaaa gtaattatag
     6901 aaacgaaaaa taaatcatat cgggcactca gacatgaaaa caaccctaga gatatataac
     6961 taggtaacca gtttaatgaa agaaaaaatc atccaagaag tcgattcttg gattttttag
     7021 tggatttgtt cgccaaatac gtttagtatg cgtatatgag aggttgtaag caaagcgttg
     7081 tggtctgagc acttaaggag gaatctgtga aaatagcttt tcatattttt gcagattttg
     7141 acttaatgcc gaaggtcagc tttgcgatta ccgtttatcg agaggctgta aaagcaccgt
     7201 gtagctccga tgacaataag caagcatttt tagagctagg tttccttgat tctaaatatg
     7261 cggcttattt caatgagttg gtgcttgaac gcgattttaa gaaggtcgaa aacaggcacg
     7321 acttttcgac gtaaggagaa agaatttcaa tgatagaaac aataaatccc gcagaaaaca
     7381 aggtttctgc gtacattcat atcccatttt gcgagcatat ctgctattac tgtgatttta
     7441 ataaagtttt tttagaaggg cagccagtag atgagtatgt ggaaatgctg ctgaatgaaa
     7501 tgaaaataat gctagaaagt catccgacag cgaatttaga aacactttac gtagggggcg
     7561 ggacaccaac ttctttatct gctaaacaac ttgatcgact gttatcaggt gctagagaga
     7621 tcctgccttt tcaaaatggt aatgagttta ctgtagaagc gaatccaggt gatttgaccc
     7681 gtgaaaaact tcaagtaatg aaaaactatg gcgtcaatcg tttatccatg ggagtgcaga
     7741 catttgataa tcgcttattg aaaaaaattg gacgtaaaca caccgcagaa gatgtgtatc
     7801 aaactatgca atttttagaa gcagaaaatt ttaccaatgt aagcatcgat ttgatttatg
     7861 cattaccggg acaaacacta gaaggatatc tggatacttt ggaaaaagct ttggctttgg
     7921 atctgcctca ctattctttg tactcattga tcctcgaaaa caaaacaatg ttcatgaact
     7981 gggtacgaca aggaagactc gaactgcctg atcaggaaac ggaaaccaga atgtttgaag
     8041 agacgattga agcaatggaa aagcatggac gtcaccaata tgaaataagt aactttgggc
     8101 tctccggaca tgaatctcaa cataacctca tgtactggaa caatgcccac tattttgggt
     8161 ttggagctgg tgctagcggt tatcttggag atattcgtta ccgcaacaaa ggaccaatcc
     8221 aacactattt acgcccatta cgagcaaatg aacgcccggt attggaagaa gaaaaattga
     8281 cacgaaaaaa tcaaatagaa gaagaaatgt tcttaggact aagaaaaaaa acagggatta
     8341 ctaaaaaaca tttctatgat cgctatcaaa aaacaattga atcggtgtac ggtgatgtgc
     8401 taagggaatt agagcaagaa gggttacttg ttaatgaaga agaccgtgtt tatttgacac
     8461 caagagggac ctttttgggg aacaatgtgt ttgagcgctt tttgtttgaa aaatagttta
     8521 aagaatattt gttttttatc tgaatttaaa taaaaaaagt tcaaaaatac aataaaggac
     8581 tattgaaacg ttgatataac tggatttaca tcaattattt agaattagca ctcttgtgtt
     8641 tagagtgcta aaaaatggag tctttctctt gacaggagaa gggcttcttg ctatatttat
     8701 aagtggatta gcacttagaa tatatgagtg ctaatgagag gtgaggaaga tgttaacaaa
     8761 gcgacaaaac gacattttac gtctgatcat ccaacactat acgagtagtg gcgtgcccgt
     8821 tggttccaaa acattgatgt ctgagggagt caaggccagc tcagcaacga ttcgcaatga
     8881 tatgaaagca ttagaagatg aaggattgct gttgaagact cactcttctt ctgggcggat
     8941 tccatctgct ttaggctatc gttattacgt ggatcatttg ttaaaacctg ctcgcgtagc
     9001 agaagatgat ttgctgctga ttcgtcagtc tctaggcaga gaatttcatg aaatcaatga
     9061 gattattaag caatctgctg agatattatc tgagctgaca agctatacga ctttttcatt
     9121 gggacctgaa ataaaagacc gccgactgac tggctttcgt atcgtaccct tgaataatcg
     9181 acagattatt gctatcgtcg taacagatat ggggaatgta gaaagccaag tgttcactct
     9241 tcccgaatat atgggaagtc aggaactaga aaaaatggta cagattgtaa acgaccgtct
     9301 agtcggagat cctctgatga cggtgtacca taaacttcgt acggagattc cgatgattct
     9361 tcataaatat ttccaaacga cagaagggat gtctcagtta tttgacaccg ttcttggtca
     9421 tgtttttgaa gataaggttt atgtcagtgg acaaatgaat ctcttggatt atgagccccg
     9481 tcaagatctt gatcagttca aatcgatgtt ttcttttatg aaagactcag acggacttac
     9541 acaaatgatc actccgatgg atagcaatat tcatatcaag attggtgctg aattaggcaa
     9601 tgatttattg cagaatatga gtatgattca agcaagttac gagatagatg gtcatggaag
     9661 aggtacaata gccttgttag ggcctactag tatgccttat tctcggatgt tcggtctagt
     9721 cgatgtttat cgaagagaac tagcagctaa acttgctgat tactaccgtt cgcttgactt
     9781 gtcaaactcg taatgtgaat aacgaagcta tttgcagctg atcgttctct ctttcttagt
     9841 aagagcaatc aaacagctga ctgaataatg aaaggaagac tgtatcgtga aagaaaatca
     9901 agaagaacta gataaagaaa tgacagatgc tcagccagaa ccggaaatcg atgtcgaagc
     9961 tgcagaagat tcgggtattt cagaagctga agcggaagaa ttcgaaacag cgaaattaaa
    10021 agctgagtta gaagaaatgg aagataaata cttgcgggct cgtgctgaaa tcgcaaatat
    10081 ggcaaatcga ggaaaaaatg agcgtgagca attacaaaaa taccgttcac aagatttagc
    10141 caaaaaatta cttccatcaa ttgacaacct ggaacgtgca ttagccacag aagtgtcaga
    10201 tgatcaaggg gcaggtttga aaaaaggcgt ggaaatggtc ttggaaagtt tgcgtaacgc
    10261 actggaagaa gaaggaattg aaaaaatccc tgctaaagga gaagcctttg atcctaatct
    10321 tcatcaagca gtacaaactg ttccagcgac tgaagataca ccagccgata cgattgtaga
    10381 agtactacaa gaaggctaca aattacatga tcgcgtgtta agaccaacca tggtcattgt
    10441 tgcacaataa ttgtgcggat ataaaactta cactttcaat taaagaagga gacgttaatt
    10501 atgagtaaaa ttatcggtat tgacttaggt acgactaact ctgcagtagc agtattggaa
    10561 ggaaacgaag caaaaatcat cgctaaccca gaaggaaacc gtacaacacc ttctgttgta
    10621 tcattcaaaa atggagaaat ccaagtaggg gaagttgcaa aacgtcaagc tgtgacaaac
    10681 ccaaatacga tttcatcaat caaacgccat atcggtgaag caggttacaa agtagatgta
    10741 gaaggtaaat catatacacc acaagaaatc tcagcaatga tccttcaata tatcaaagga
    10801 ttcgcagaag actatttagg tgaaaaagtc gaaaaagcag ttatcactgt gccagcttac
    10861 tttaatgatg cacaacgtca agcaacaaaa gatgctggta agatcgctgg tctagaagta
    10921 gaacgtatcg tcaatgaacc aactgcagct gctcttgcct atggtttaga taaaacagat
    10981 cgcgacgaaa aaatcttagt attcgacctt ggtggcggta cttttgacgt atctatcctt
    11041 gaactaggag acggtgtctt tgatgtattg tcaacagctg gcgacaacca tctaggtggg
    11101 gacgactttg ataacaaaat catcgactac atggtagcag aattcaaaaa agaaaacagc
    11161 attgacttgt ctcaagacaa aatggcttta caacgcttga aagacgctgc tgaaaaagcg
    11221 aaaaaagatt tatctggcgt atcaagcaca caaatcagct tgccatttat cacagcagga
    11281 gaatctggac cattgcattt ggaaatgaca ttgacacgtg caaaatttga tgaattaaca
    11341 gctgacttag tagaacgtac aaaagtacca gtacgtcaag cgctaaaaga tgcaggttta
    11401 tcacaatcag aaatcgacga agttatttta gtcggtggat ctactcgtat ccctgcagtt
    11461 gtagaagcag tacgtaaaga aacaggaaaa gaaccaaaca aatcagttaa ccctgatgaa
    11521 gtagttgcta tgggtgctgc tatccaaggt ggcgtgatca ctggtgatgt gaaagatgtt
    11581 gttttacttg acgttacacc attgtcatta ggtatcgaaa caatgggtgg agtgttcact
    11641 aaattgattg accgcaatac aacgattcca acaagtaaat cacaagtatt ctcaactgcg
    11701 gcagataatc aaccagcagt agacatccat gtattacaag gtgaacgccc aatggctgct
    11761 gacaacaaaa ctctaggaag attccaattg acagatattc cagcagctcc tcgtggtatt
    11821 ccacaaatcg aagtaacatt cgatattgat aaaaacggga ttgtaaatgt atctgcgaaa
    11881 gatctaggta cacaaaaaga acaaaaaatc acgatcaaat cttcttcagg tctaacagac
    11941 gaagaaatcg aacgtatggt aaaagatgca gaagcaaatg cagaagcaga taaagctcgt
    12001 aaagaggaag ttgacctacg taatgatgta gatgcattgc tattctctgt ggacaaaaca
    12061 ttgaaagaat tagaaggcaa agtggacgaa gaagaagtga aaaaagcaga aacagctcgc
    12121 gatgaattga aagccgctgt tgaagcaaac aacatcgaag aaatgaaaac taaacgcgat
    12181 gcattgaacg aaatcgttca aaacttgact gttaaactat acgaacaagc ggcacaacaa
    12241 caagctcaag aaaacccaga agcagctcaa ggcggagcag atgatgtcgt tgatgctgat
    12301 tttgaagaag tcgatggcga cgataaataa tcagttcact gaatttcgag agaaggccaa
    12361 agttgctact ttggcttttt cttttgaaaa atagtttgaa gtatcggttt ttgtttcaaa
    12421 caaaatatga tatgataaca agcgacgtga aaatgatgag aaccaatagg aggaaagcct
    12481 atggcaacaa aacgtgatta ttatgaagtc ttagggctct caaaaggagc atcagaagat
    12541 gaaataaaga aagcttatcg taagctttcg aaaaaatacc atcctgacat caataaagaa
    12601 cctgatgcgg aagaaaaatt caaagaagta tcagaagcat atgagatttt aagtgacccg
    12661 caaaaacgcg ctgcatatga ccaatacggg catgcaggca cagatccaaa ttacggtgct
    12721 ggtggagctg gtggcggatt tggtggattc ggcggcttct ctggtggcgg cttcggtggt
    12781 tttgaagata tcttcgactc tttctttgga ggaggcggtc ggtcagtcga tccaaatgcg
    12841 cctcgtcaag gtgctgattt gcaatatacg gtcgacttgt cttttgaaga agcgattttt
    12901 ggtgtagaaa aagaaatcaa gtataatcgg gaagaaatct gtcatacttg tggtgggaac
    12961 ggtgcaaaac caggcacaca accaactact tgtcataaat gtcatggtgc aggtacgatt
    13021 aatgtagaac gccaaacacc acttggacga gtgatgagcc gtcaaacttg tgatgtttgt
    13081 catgggacag ggaaagaaat caaagaacct tgtccaacct gtcatggctc aggacatgag
    13141 aagaaagcac attcagttaa agtgaatgta ccagctggtg tagaagaagg acaacaaatg
    13201 cgtttagctg gtcaaggaga agctggagaa aacggcggac catttggtga tttgtatgtg
    13261 gtcttccgtg tagaagaaag tgatatcttt gatcgtgaag gttctgaaat ttactatgaa
    13321 ttgcctttaa gttttgtaca agcagctttg ggggatgaag tccaagtacc aactgtccat
    13381 ggagatgtga aattgaagat ccctgctgga acacagacag gtacgaactt ccgtttacgt
    13441 ggaaaaggcg ctccgaagtt acgtggtggt gcaacaggcg accaacatgt caaagtaaaa
    13501 ctgatcacac cgaaaaatct aaatgaacaa caaagagaag cattacgtgc attcgctgaa
    13561 gctggcggca tcaaagttga agaacagcaa gaagacggtt tcttcgataa gtttaaagat
    13621 gcttttggcg ggaaaaagcg gaagtagttt ttctagtaaa aacgctaagt cattaataat
    13681 taaaaaccag acgaacaatc atatgttcgc ctggtttttt tgtagttgtc atgtttgtac
    13741 caacaaaaaa gccagcttta gaatatgata atcgtcatag tttctagggg tataaccagt
    13801 gagagaatgg aacttgttca atcgatattg caaggtgttt ttatgaataa ataattcttc
    13861 tgagcaattt ttgatgcttc cgttattttt actgaagcat gccaaagtct tcttgaacaa
    13921 atgtacttct tcttctgtca ggcttttcaa aatacgtttt acatataatg ttcgttgatc
    13981 tgacgggatt gctggtaaaa cgatcccgag gtctaaatct tcaaaaaagc ggatctcgtt
    14041 cacagattga tggaaagcta tccattcgca aacttgtttg gcatgaagga aagattgcgg
    14101 tgtctcttgc tctgtataac aaagcgaccc aattccaaag tttagctgta actgatacat
    14161 tttattaaac tttgtctgga ttttatcaag caatgatagc aatgaggctc tggaaatccg
    14221 attgactagg ataatgattt gttgtctatg tacagtgagc aaagcctgtc cgtaataaga
    14281 gaagaccctt tcgagcaact ccaataaagg attgatccgt tcttgacaca attgctgatt
    14341 gtcagaaagt tgtcccacaa ctacataata tggagaagaa aaatcaagct caattaagtg
    14401 agggtggtat cgactatgta cttgatatca tcaatgaacc gatggtactt tcttatgcga
    14461 tggaacaggt agagcgattg cttgtttgtg caggaaaaca agcgatgcgg ctgatacgat
    14521 taggtgagaa aataagaaga taaaaataca cggtcccttc atggcgaccg tgcatttttg
    14581 gtttttatta aatatttaat actttattca agaaatcttt tgtccgttca ttttgcggat
    14641 tttcaaagat ttgttgaggc gttccatctt ctaaaaagtt tccgtcgtca atgaacatga
    14701 cgcgattggc cacttcttta gcgaacccca tttcgtgcgt aacgataacc atcgtcatac
    14761 cttgttctgc taactttttc atgacgttca agacatcacc gaccatttca ggatcgagtg
    14821 cagaagtagg ctcatcaaaa agcatgatgt cagggttcat cgctagagca cgagcaatag
    14881 ccacacgctg tttttgtcca ccagaaagca tttcaggata catatctttt ttatcttcta
    14941 gaccaactgt ctgcagtaat ttgattgctt ttttctctgc ttcttctcta gattctttct
    15001 tcaggtccat cggtgctaaa atgatgtttt ccaaaataga aagatgaggg aataggttaa
    15061 agtgttggaa taccattccg atatgttgtc tcaccaagtt gatatctgtg cttttatcca
    15121 tcaagtgggc gccgtcaata ataatttcac cgtcagaagg ttcttctaaa cgattcaagc
    15181 aacgcaagaa tgtacttttt cctgaacctg aagggccaat gatacagacg acatctcctt
    15241 cgttgatgga tacattgatg tcgtttaata ctgtgttatc gccgtatttt ttgactaaat
    15301 gctcaactaa gattttttct gccatcttac ttcaccttct tttctaaaac ttttgctaat
    15361 tttgtcaatg ctgtgatcaa aatcaagtac atgatcgcaa tgatcaagta aacatacgta
    15421 ctttgtgttg tacgtgcaac aatgatctta ccagtttgca gcaattcgac tacaccgatt
    15481 gcggaaatga tcgttgtgtc ttttaatgag ataacgaact gattgacgaa tgatgggatc
    15541 atgatgcgta tcgcttgcgg caaaatgatt ttttgcattg tccgattata agaaagacct
    15601 aaacttctgg aagcttccat ttgtccgaca ggaacggcgt tgatcccgcc tcgaacaatc
    15661 tctgcgatat aagcacttgc gttaagagtc aaggtgataa caccagcaag gaagtcagga
    15721 atcgtaaatc caacgatacc aggcaaccca aagaaaataa agaacgcaag aaccatcatt
    15781 ggaattcctc ggatgatatc gacataaata ctagcaattg tgcgaagagc gcgtattggt
    15841 gctacactga ataatccaaa aatcacaccg attactatag ccaaagcaaa ggagatcaaa
    15901 gttaggagaa ttgttctcca aagtcctttc aacaatgctt gatagttgtt ttggataagt
    15961 ccaagaaatg ttgattcatc agcagtggaa gactcactgg aagtttctga accatccgct
    16021 acatattctt taataatctt atcgtattcg cctgttcttt ttaattcttt caatccttca
    16081 ttgaacatat taagaagctc aggattttgt ccttttttaa cggcaaatgc atattttccg
    16141 ccagattctt ttttgatcgg tgtttccaat tcttgtcctt gtttgatcgc ataaccgatt
    16201 accggataat catccatcat tgcatcgatt gcgccaactt ttaacccgtc gtacaattga
    16261 tcagcagcat caaaatattt gatagaatag ccatattcag attcatggtc gcttaaaaat
    16321 tcagcacttt cggtaccaac ttttgctccg actgtttttc ctttcaaatc ttcataagac
    16381 ttgatcgaag tatctccttt tttgacagct aattggatcc cgctatcaaa gtaagaatca
    16441 gaaaaatcat agcttttctt tcgttcatct gttacagtca ttccggcaat cattccgtct
    16501 gcttgtcctg attccaaagc ttgcaaagca gcagagaaac cacggtagtc cattcggatg
    16561 ttaaatcctt gcagtttggc gatgttttcc atcaatttta catcgatgcc ttcgtactcg
    16621 ccctttgcgt tttgaaattc aaatggagca aaagcagagt cactggcaat tacgtatacg
    16681 tcttttttgg gctctatttt ttgcattgtc tcgcttgtgc ttgactctgc cgttgtagtg
    16741 ttgtcagctt gtgcaacatg accaaacgca agtgtcacaa gtcctgtcat taagaaaaca
    16801 aatgagtgaa ataaatgctt tcttttcata atcaacctcc taaatttcca atattttatt
    16861 attataggcg aaaagtgctg aatcagacaa gactgtaagc tcgaaaaaat gaaaaaaatg
    16921 cgagtttcta acattttatg ttataaaaca taacatgtat aataagataa aaaagtggcg
    16981 aaagtatgtt cggtgtggta taatttttta gtaaggaatg cctttgcttt ccttttcttt
    17041 ttattggtcg taaaatgaaa aggaatgaat gaaaaggagg acgaagaatg attgagagag
    17101 atacctcccg acactttgag cttgtctcga aataccaacc ggctggtgat cagcctgaag
    17161 cgattaacca attagtggat ggcgtagtcg gcgggaaaaa agcacaaatc ttattaggtg
    17221 cgactggaac agggaaaaca tatacgattt ccaatcttat tgagaaagtg aataaaccaa
    17281 cactgattat tgcccataac aaaacattgg ctggtcagct gtacggggaa ttcaaggaat
    17341 ttttccctaa caatgctgtt gaatattttg tttcttatta tgattattat cagcctgaag
    17401 cttatgtgcc ttcaagcgat acgtatatcg aaaaagattc aagtgtaaat gatgagatcg
    17461 acaaattacg acattcggct actagttcat tattagaaag aaatgatgtg atcgtcattg
    17521 catccgtttc atgtattttt ggattaggct cgccttttga gtaccaaaaa caagtagttt
    17581 cgattcgaca gggagcagaa ctagatcgca atcagttgat tcgtgactta gtcagtatcc
    17641 aattcgaaag aaatgatata gattttcagc gcggtcgttt tcgagtgcgc ggtgatgtcg
    17701 tggagatttt tccggcttca agagatgaac gtgccttacg tgtggagttt tttggagatg
    17761 aggtcgaacg tatccgagaa gtcaatgcac tgacaggtga agttttagga gaaacggaac
    17821 acgtagcaat cttcccggcg actcactttg tgacgaatga tgaacatatg gagcatgccg
    17881 tagcgaatat caaagcggaa ttagaacagc gtttaactgt cttgcgaaat gaaaacaaac
    17941 ttctggaagc tcaacgttta gaacagcgaa ccaattacga tattgaaatg atgttagaaa
    18001 tgggctacac gtcgggaatt gaaaattatt ctcggcatat ggacggacgt aaagaaggtg
    18061 aaccgcctta tacgctattg gatttctttc ctgaagattt tttgatcgtg gcggacgaat
    18121 cgcacgtaac catgcctcaa atcagaggaa tgtataatgg tgaccgagcg agaaaacaga
    18181 tgctagtaga ttacggtttc cgtttgccat ctgctttaga caatcggcca cttcggttag
    18241 aagagtttga aaaacatgtc aatcagatca tttatgtctc tgcgacgcca ggaccatatg
    18301 aacatgaaca aacagatacc gttatccaac aaatcatccg tccgacaggg ctgcttgacc
    18361 cagtgatcga agttcgtcca atcatgggac aaatcgatga tctagtaggc gaaataaatg
    18421 aacgagtcga aaaagaccag cgggtgtttg taacgacatt gacgaaaaaa atggcagaag
    18481 acctcacaga ttatttcaaa gaattaggga tcaaagtcaa atatttgcat agtgatatca
    18541 aaacgctgga acgaacagaa atcattcgag atcttcgatt aggtgaattt gatgtgttag
    18601 ttggaatcaa tttgcttcgt gaaggattag acgtacctga agtttccctt gttgctatct
    18661 tggatgcgga taaagaaggc tttttacgta gtgaacgttc cttagtccaa acgattggac
    18721 gagctgctcg gaatgaagaa ggtaaagtaa tcatgtacgc agacaaagta acagattcta
    18781 tgcgtctagc gatggatgaa acgtcaagac gtcgtacgat tcagcagaag tacaatgaag
    18841 aacatgggat cgttccaaaa acgatcatta aagaaatccg agatttgatt tctattacga
    18901 aagaatcgga agatgataca aaagaagcgg tacaagtctc gtacgaagaa atgacgaagg
    18961 aagaaaaaga cacgttattg atgaaattag aaaaagaaat gaaagatgcg gcaaaagctt
    19021 tggattttga aacagccgcg aatgtgcgag atatgatttt agaattaaaa gcttcaaagt
    19081 aggaggacaa catggctaac gataaaatta cgattcatgg tgcacgtgcc cataacttga
    19141 aaaatataga tgtaacgatt ccacgagata aattcgtggt cgttacaggt ttgtccggtt
    19201 ctggaaaaag ttccctagca tttgatacgc tgtacgctga agggcagcgg agatacgtag
    19261 agagcctttc tgcttatgct cgtcagtttt taggacaaat ggataagccg gacgtagata
    19321 gcatcgacgg attgagtccg gcgatttcta ttgatcagaa aacaacaagt aaaaatcctc
    19381 ggtcgacagt aggtactgtg acggaaatca atgactattt acgcttgttg tttgcacgtg
    19441 taggacatcc gatttgtccc aacgatcata tcgagattac cagtcaatca gtagatcaaa
    19501 tggcagatca agtaatggct ttgcctgagc gcacaaagat ccaagtgttg gcaccgatcg
    19561 tggtaaagaa aaaaggacaa cataaaaaaa tattcgaacg aatccaaaaa gagggatacg
    19621 tccgcgttcg agtcgatggt gagatctatg atttaagtga agtgcctgag ctggagaaaa
    19681 acaaaaaaca tgatatcgcg atcgtcatcg accggatcat tgtgaaagaa gggattcgtt
    19741 ctcgcctatt tgattcttta gaggcggccc tgcgattagc agacggctat gctctggttg
    19801 acgtgatcgg tgaagaagaa atgttgttta gcgaacacta tgcctgtcct tattgcggat
    19861 ttactgttgg cgaactagaa ccaagactgt tctcattcaa tgcgcctttt ggagcttgtc
    19921 cagactgtga tggtttaggt gtcaaattag aagtcgatca agatttagtg attccagata
    19981 gaacgaagac acttagtcaa ggtgctatcg ttccatggaa tccaatcagc tctcagtatt
    20041 atcctcaaat gttagcgcag gcttgtgaaa gtttcggtat cgatttagat acaccattcg
    20101 aagaattacc ggaagagcat caggagatca tcttgaatgg gacagatgat cttttccatt
    20161 tccattatga aaatgatttt ggtggcgttc gcgatgtaga aacgactttc gaaggggtat
    20221 tgaagaatat cgagcgtcgt tatcatgata cgaacagtga tttcacgcgt gagcaaatgc
    20281 gtctttatat gacagaatta acttgtcaga catgtaaagg ttatcgattg aatccccaag
    20341 ctctatctgt tcaaatcaat ggaacgaata tcgggcaaac aaatgagttg tctattcaaa
    20401 aagcagtaga tttcttctca aacttaacgt tatctgaaca agagaaagta attgccaaac
    20461 cgattttaaa agaagtaaat gacagacttt cattcttgga aaatgtggga ctagactatc
    20521 taactttgag tcgcgcttcc ggaacattat ctgggggaga agcgcagcga atcagattgg
    20581 ctacacaaat tggatcgaat ctttctggag ttttgtatat tttagatgaa ccatcgatcg
    20641 gattgcatca acgcgacaac gatcgactga ttggctcatt aaagaaaatg cgtgatcttg
    20701 gcaacaccct cgttgtagtc gaacatgatg aagatacgat gtgggcagca gattatttga
    20761 ttgacgtcgg acctggggcc ggagaacaag gcggacaaat cgtggctgca ggcactcctg
    20821 aagaagtagc taatgatgaa aattctttga cagggaaata tctttcaggg aaaaaatcaa
    20881 tccctgtacc aaaagaacgc cgtaaaggta atgggaaagc aatcaagatc actggtgctt
    20941 cagaaaacaa tctgaaaaat attagtgttg aatttccatt aggagaattt gtagcagtca
    21001 caggtgtgtc tggttctgga aagagtacat tggtcaatag tatcttaaag aaatcgttag
    21061 cgcaaaaatt aaataagaat tctgctaagc caggtaaatt caagacaatt tccggctacg
    21121 aaagtatcga aaagatcatc gatatcgatc aaagcccaat cggccggacg ccgagaagta
    21181 atccagcgac ttatacaagt gtatttgatg atatccgtgg gttatttgct caaacgaacg
    21241 aggcaaaaat gcggggttat aagaaagggc gttttagttt caacgtaaaa ggcggtcgtt
    21301 gtgaagcttg tcgcggggat ggaattatta agatcgaaat gcactttttg cctgatgtct
    21361 atgttccttg tgaagtatgt catggtaaac gatataattc tgaaacatta gaagtgcatt
    21421 acaaaggaaa aagcattgct gatattttgg aaatgacagt agaggatgct gtagaattct
    21481 tcaagcacat tccaaagatt catcgcaaac tgcaaacgat tgttgatgtt ggcttaggtt
    21541 atgtgacgat ggggcaacca gcaacgacat tgtccggtgg tgaggcacaa cggatgaaac
    21601 ttgccagtga attgcacaaa atctctaatg gaaagaattt ctatatacta gatgaaccaa
    21661 cgacaggact tcatagcgat gacatcgccc gcttgttgca tgtattacaa agattagtag
    21721 atgctggtaa cacagtttta gtgattgaac acaatctaga tgtaatcaaa acagcagatt
    21781 atatcattga tttaggacca gaaggtggag aaggtggagg aacgatcctt gcgactggaa
    21841 caccagaaga aatcattaac gtaaaagaaa gttatacagg tcactatttg aaaaaaataa
    21901 tggtataaag aggatagata gctgagatag ttaaaaaaac ataaaaaaat gaatttttgc
    21961 ttgttttatt aatatcagtg ttctagaatc attacatggt agttctttct acactgattg
    22021 gtatagataa aaacttccta taagttcaat ccgttcaaaa aagaattgag caatcggagg
    22081 actttccttt gattgctttt ttctttatgg tatgatattc cttgtgtagt tggaaaagaa
    22141 aaacaagaga ttatgagtaa gtgagagata atgatgaaca gtattgaaaa tgaagaattt
    22201 atccctatat tattaggaag cgacatgaac gtttatggta tggcacgttc ttttaatgaa
    22261 gcatacggca aaatctgcca agcatatgct tcggatcagt tagcccctac ccgctacagt
    22321 aaaattgtca atgtagaagt tattccagga tttgataaag accctgtatt tatcgagacg
    22381 atgcttcgtt tggcaaaaga aagatattct gataagagta aaaaatatct tttgattgct
    22441 tgtggtgatg gatatgcaga attgatctcc caacataaac aagagctgtc agaatatttt
    22501 atctgtccat atattgatta ttctttattt gaaaggctga tcaataaagt aagcttttat
    22561 gaagtttgtg aagaatatga tcttccgtat cctaaaacat tgatcgtcag agaagaaatg
    22621 ttagtaaatg gacatttgga acaggaattg ccttttgaat tcccagttgc tttgaaacct
    22681 gcaaacagtg tggagtatct ttctgtccaa tttgaaggaa gaaaaaaagc ttttatttta
    22741 gagactagag aagagttcga tttaatttta ggccggatat acgaagccgg ttataaaagt
    22801 gaaatgattg tacaagattt tatcccgggt gatgatagta atatgcgtgt gctaaatgcg
    22861 tatgtagatg aagatcatca agttcggatg atgtgccttg gtcatccact attagaagat
    22921 cctacaccag catcgattgg taattacgtt gtgatcatgc cagattataa cgaaaaaatc
    22981 tatcaaacca ttaaggcatt tttggaaaaa atcgaatata caggctttgc caatttcgat
    23041 atgaagtatg atcctagaga tggagaatat aaattatttg aaatcaattt gagacaaggt
    23101 cgtagcagtt tctttgtgac attgaacggc ttgaatctgg ctcgttttgt cacagaagat
    23161 cgagtgttca acaaaccctt tgttgaaacg acctatggaa cgaatcaatc agataaagca
    23221 agattatgga tgggtgtgcc caaaaaaatc tttttagaat atgctcggga aaatgaagac
    23281 aaaaaactag ctgagcaaat gatcaaagaa aatcgttacg gtactactgt attttatgaa
    23341 aaagaccgat caatcaagcg ctggttgttg atgaaatata tgttccataa ctatattcca
    23401 agattcaaaa agtattttca tgtgaaagaa ggctagttca tggagaattt tttcagtatt
    23461 ttaggcggaa tgggcacgat ggcgacagaa agttttgttc gcttgatcaa ccaccgaacg
    23521 aaagctacaa aagatcaaga atatttgaat tatgtcttat tcaatcatgc aacagttcct
    23581 gatcgtacag cttatatttt agatcgatca gaagaaaatc caatgccgtt tctgctggat
    23641 gatattgaga aacaaaattt attgcgacca aacttcattg tgttgacttg taacaccgca
    23701 cactactttt ttgaagagtt acaagcggca acggatattc ctatcttgca tatgccaaga
    23761 gaagcagcaa atgaacttgt ccgtcagcat acgacaggga gagtagcgat tctaggaaca
    23821 gaaggaagta tgaaagctgg aatctatgaa cgcgaagtca aaaatcttgg tttcgaaaca
    23881 gtgattcctg atactgcgct tcaagaaaaa atcaattacc tgatctatca tgagatcaag
    23941 gaatcggatt atttgaatca agagctctat tacgaaatct tagaggaagc ggtagagcgc
    24001 ctaaactgtg aaaaagtcat cctaggttgc acagaattat ctttgatgca tgaatttgct
    24061 gaagataatc attacccagt gatcgatgct caatctattt tagcggatcg aacgatcgaa
    24121 cgtgcattag ctgaaagaag cgaggcattg gatacagcat cggaaaagta aaaaaattgg
    24181 atttggggca aatatcctaa aagatatttg gtccaaatct ttttgtaaaa gaaaaagaaa
    24241 actggtaatg atacgcccgg gatgatataa ttttattatg cacaatgtga gaggggttcg
    24301 taaatatgac agataatttg caattagtca tcataacagg tatgagtggt gcagggaaaa
    24361 cagtagctat ccaaagtttt gaagatatgg gctatttttg tatcgataat atgccgcctc
    24421 gattgattcc aaaattctgg gaattgatca aagaatcagg taaagtcaca aaaatggctt
    24481 taggagtgga tttgcgttct cgttccttct ttgaagaaat ccaaaacatg ctgatcgaaa
    24541 tcgaaaatac gaacttcatc gacacttcta tcttattttt agatgcttca gacgaagaac
    24601 tagtggctcg ctacaaagaa acaagacgag cacatccaat ggcgatggac ggtttgatca
    24661 ctgaagggat acgtaaagaa cgggcgatac tagacgactt gaaagcccaa gcttccgtga
    24721 tcattgatac gacaacattg acaccacgac aattacgtga aaaaatcaat gagtcattca
    24781 aatcaaaggg agaccaagga tttcggatcg aatttgtatc atttggtttt aaatacgggt
    24841 tgccgatcga ttcggatatt gtgatggatg tgcgtttttt gcccaaccct cattatatcc
    24901 cggaactaag accattgacc ggaaaagatc agccagtcta tgattatgtg atgtcctttg
    24961 atgaaacgca atcattctac cataaatttt tggatcttct ggaaactgta ttgcctggat
    25021 acattaaaga aggaaaaagc agcttgacag ttgcaatcgg ctgtacaggc ggtcaacacc
    25081 gttctgtggc attgactgaa cgtttggcaa atgctttagg gaaaaactat aaagtcaatg
    25141 tgacacatcg ggacaaggat aaaaggaaag agacggtgaa ccggtcgtga aaatgaaaac
    25201 ctaccggata agaaaaccaa agatcgtagt ggtcggcggt ggcactggtc tgccagttat
    25261 cctgaaaagt ttacgaaatc aaggagcaga tatcacagca gtagtgactg ttgcagatga
    25321 tggtggaagc agcggtgcaa tcagagaatc gatcgctatg gctcctcctg gtgacttgag
    25381 aaatgtctta gtggcgttat cggatatgcc acaattctat gaagatattt tccaataccg
    25441 tttcaaaaag gaagatcagt ttttagccaa tcatacgatc ggtaatctga tcattgccgc
    25501 agtttccgag atgcggggaa gcacttatga ggcgattcaa ttattagcaa aaatgatgca
    25561 tgtagatgga catgtttatc cttcttcaga aactcctttg accttgcatg ctgtttttaa
    25621 agacggaacg actgcagtag gagaatctaa aatcgcgatc aaccgtaaaa ccattgaccg
    25681 tgtgtatgtc tgcaacacaa atgataaaag tgaagccaaa gcggctcgaa aagtcgtttc
    25741 agcaattatg gacgccgaca tggtcgtttt gggacccgga agtttattca ccagtatcct
    25801 tccaaattta gtgataccag aaatcggcga agcaatgctc aagacaactg ctgaaaccgt
    25861 ctatatctgt aatatcatga cccaaaaagg ggaaacggaa catttcacag atgccgatca
    25921 tatacgtgtt ttacacaagc atttgaatca gccttttatc gatacagtat tggtcaatac
    25981 ggaaaaagtg cctgaagatt atatggaccc agagatctat gatgagtatc tagtacaagt
    26041 cgcacacgac ttcaacggat tgagaaatga aggatgtcga gtgatttcca ccgacttttt
    26101 agaattgaaa gatggtggtg tcttccacga tggagacaaa gtagtagaag aattgttccg
    26161 tttagttttc ggttcaaaat attaagcaat ttattgttgg agaaaggagg agaataggat
    26221 gtcatttgct gcagatgtga agaaagaact aactggtttg gaagttcatc gagaacatgc
    26281 gaaagcggaa ttagctgctt tgctgcgaat gaacggctct ttaggtattg tgaaccagca
    26341 gtttattttg aacgtccaaa cagaaaatgc tgcaattgcc agacgtatct attctctttt
    26401 gaaagatcat tatcaggtac gaagtgagct actcgttcgt aaaaaaatga aattaaaaaa
    26461 gaacaatgtc tatatcgtcc ggttgaagca aggcacaaaa gatgtgttga tggatcttga
    26521 tatcatggat ggtatgatgt tcaatggaca cgtttcggac gagattatgg gaaattcgca
    26581 aaaaatgcgt tcttacttac gtggtgcttt tatggcctca ggttcagtca ataatccgga
    26641 aacgagtcgt tatcatttgg aaatattttc tatttatgaa cagcataacc aagacatttg
    26701 cgatatgtta aattattacg gtctacatgc tcgaacgctt gaacggcgca atggctatat
    26761 ttcgtattta aaaggagcag aaaaaattgc tgatttctta acattgattg gtgcaaccaa
    26821 ctcaatgctc cgatttgaag atgttcgaat cgtacgggat atgagaaatt cggtcaatcg
    26881 tctagtcaat tgtgagacag caaatctgaa caagacgatt gatgcggctt ctaaacaaat
    26941 cgaaaacatc gaattgatcg aagcaaaggt cggtctacat gcccttcctg aaaaacttca
    27001 ggaaatcgca gaacttcggc ttcaacatcc agaggtcagc ttgaaagaat taggggaaat
    27061 gattccctca ggtgcaatat caaaatcggg aattaatcac cgaattcgca aaataaatga
    27121 atttgcggaa aaactgcgtg aagaagcagt ttaatccaaa gaaaaaactg atacatgaag
    27181 caggagatgc gaatgtatca gtttttttta aaagctatac ttgcttttct tccgtcaaac
    27241 tataattcca actttactgg agtaacataa tgttgaaagg cttctattgt tttttaatac
    27301 aatcgtataa aaagcgggga gacaactgaa tgaagatttt agttttatac ataaactttt
    27361 gcttaatata gaagtcctga tatagatagg atcaagtatt tatctataac tggagattaa
    27421 ttaaaaactg gaaggaactg ctcgatcaac cttgagaact gtttttctta cttctggtca
    27481 agattctcgt ggttggtgga taaggatggt tgataagttc attggattag ctagtcgaaa
    27541 acaaccaggt gtaattaatg tagaagtttt aacaagggga tggagtgatt tattcagtga
    27601 taatcataag ttcataaata gtaattggga tgtatggttg gtatacgtta tacctgaact
    27661 tgaactatca agatttggtt tagaatttga gaatcgatgt ttataaaggg agggcaaaaa
    27721 atgtgctttt ttacaacttt tactatcatt atgattgcag tactttttat ttttctagat
    27781 atagcaaagc gaaatacagc atttttatta tatcgggttt tacttcgagc aggtctcata
    27841 acatttatat cgatcgttgg attttttcta ttcacagtta ttgtatttat ttggagaact
    27901 acagcaccac cattgccaga gattacatat ggagaatttc cgtttagtct tgaatatgaa
    27961 atagatgagg aaagaatttt gattgaagat acggtgattg cagaatttat aggaagtttt
    28021 agagggaatg tgacaactca acctagacga agttggagta taaaactttt aaataatagt
    28081 ggagagttga aagcatttca ttatgaattc ttaataatag aaagtgaaga tgtaacaatc
    28141 actttaagta gtggctctgc tggatatttt atgaatgatg gtggaagcaa gccacagctc
    28201 acagtccgtg atcgtattgc aggttttatg catttttctc actatgactt agaagaagct
    28261 cgtaaaatac ttgcagaata tgggatcaca ttaatcaatt gggaatatgc gccaccgata
    28321 agaaattttt tcaatgatta ttattagtct tataaaaaac agaatgtaaa atttatgtgc
    28381 gcgagtattt agttttccat tttttgtttg atagatatat agcattgttg aagcatggga
    28441 tagtggtgcc aattttatca atgaggttgg tcaggcagtt aacataattg gtgatgctat
    28501 aaatccattt aattggaatt ggaggaatta ggtgtggaaa cagtgagatt atggatattc
    28561 atgaaaaatt ttcgttcggc tttgagatat gttattctgg aatcaaaatc aggttattat
    28621 ctgattgaca cagatcacta tactttttgg ggaggctacc tttttccgat ttttaattgg
    28681 ataatccccc ataaggttat gaaaattaac ttgcctgcag aagaaataaa tagattaata
    28741 ctcaacaaag atttacaaag gaaaagagag aaagaacatt ctaatgttgc ttggataggt
    28801 ccagcatttg cagtagtgac ttcttcaatt gtcggtccta tgctagagag tatttatagt
    28861 gatttttcta ttggaatacg ttatttattt gttactttaa gtatagctgt tcttttgtgc
    28921 ataaagggtt atgttagcaa gaagaataaa gatattttaa cactaatcgg tgtaaacaat
    28981 ttatctagta ctaaaattat actgtttcct gaatctataa aagaaggatc aaggttgttg
    29041 ataattttta taatgcttat actgttttct gttttatttg gggtgatgtt tataga
//
LOCUS       DADVXV010000031        28130 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.031, whole genome shotgun sequence.
ACCESSION   DADVXV010000031 DADVXV010000000
VERSION     DADVXV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.031"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(97..576)
                     /locus_tag="KB969_001272"
     CDS             complement(97..576)
                     /locus_tag="KB969_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6869273.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(649..933)
                     /locus_tag="KB969_001273"
     CDS             complement(649..933)
                     /locus_tag="KB969_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869274.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(1011..1205)
                     /gene="ssrS"
                     /locus_tag="KB969_001274"
     ncRNA           complement(1011..1205)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KB969_001274"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(1277..2563)
                     /locus_tag="KB969_001275"
     CDS             complement(1277..2563)
                     /locus_tag="KB969_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBB6869275.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            2701..3372
                     /locus_tag="KB969_001276"
     CDS             2701..3372
                     /locus_tag="KB969_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBB6869276.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            3338..3826
                     /locus_tag="KB969_001277"
     CDS             3338..3826
                     /locus_tag="KB969_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBB6869277.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            3839..4786
                     /gene="prmA"
                     /locus_tag="KB969_001278"
     CDS             3839..4786
                     /gene="prmA"
                     /locus_tag="KB969_001278"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBB6869278.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            4787..5551
                     /locus_tag="KB969_001279"
     CDS             4787..5551
                     /locus_tag="KB969_001279"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBB6869279.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            5784..7997
                     /locus_tag="KB969_001280"
     CDS             5784..7997
                     /locus_tag="KB969_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBB6869280.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            8008..8454
                     /locus_tag="KB969_001281"
     CDS             8008..8454
                     /locus_tag="KB969_001281"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBB6869281.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            8625..9884
                     /locus_tag="KB969_001282"
     CDS             8625..9884
                     /locus_tag="KB969_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBB6869282.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(9973..10920)
                     /locus_tag="KB969_001283"
     CDS             complement(9973..10920)
                     /locus_tag="KB969_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6869283.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            11314..12606
                     /locus_tag="KB969_001284"
     CDS             11314..12606
                     /locus_tag="KB969_001284"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBB6869284.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            12621..14390
                     /gene="aspS"
                     /locus_tag="KB969_001285"
     CDS             12621..14390
                     /gene="aspS"
                     /locus_tag="KB969_001285"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBB6869285.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            14499..15374
                     /locus_tag="KB969_001286"
     CDS             14499..15374
                     /locus_tag="KB969_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6869286.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            15640..17523
                     /locus_tag="KB969_001287"
     CDS             15640..17523
                     /locus_tag="KB969_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6869287.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(17598..17882)
                     /locus_tag="KB969_001288"
     CDS             complement(17598..17882)
                     /locus_tag="KB969_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6869288.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(17872..18606)
                     /locus_tag="KB969_001289"
     CDS             complement(17872..18606)
                     /locus_tag="KB969_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBB6869289.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            18735..19358
                     /locus_tag="KB969_001290"
     CDS             18735..19358
                     /locus_tag="KB969_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBB6869290.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            19550..20671
                     /locus_tag="KB969_001291"
     CDS             19550..20671
                     /locus_tag="KB969_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBB6869291.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            20678..23806
                     /locus_tag="KB969_001292"
     CDS             20678..23806
                     /locus_tag="KB969_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBB6869292.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            23825..27019
                     /locus_tag="KB969_001293"
     CDS             23825..27019
                     /locus_tag="KB969_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBB6869293.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(27165..27872)
                     /locus_tag="KB969_001294"
     CDS             complement(27165..27872)
                     /locus_tag="KB969_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6869294.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT         9369 a         5021 c         5989 g         7751 t
ORIGIN      
        1 cattataaag accgatgagt gcttgccgcg tcttttgttt ttatcacggt tttttgtgca
       61 aaaaaacctg ccgatagttg gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc
      121 tggcaattgg ttttctaaat cagttcggac aacaagcaca tcgcaagctg cgtttctaat
      181 aacatattca gaaacagaac caataaataa acgttctaca gcattcaatc ctgtggctcc
      241 taacataatc aaatctactt gattatcttc tgggatttct ctggcaataa tttgttttgg
      301 tgagccatat tctacgacag aggttacatt attcaagcca gctttcttcg cattgctttc
      361 ataatctgcc aatgtttgct ttgccatttc agtagcttgt tctgcaagca ttccatcaaa
      421 ggatgaaacg gtttggaaag aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt
      481 atttcggata gctacattga ccgccttttt aaaagctaat tcagcttcat cagaaccatc
      541 tacggcaacc atgatttttt tgtattgttg taacataagc attcactcct caagtcaatc
      601 gtattgtact cttttattgt agaacacttt agggaaaaag agaattattt actgctttgg
      661 ttcagcaatt ttttttgcaa atcggatact gaaggtggca gaaacaataa ttacgatcag
      721 taaaaagacc aaggcaataa agcgttgatt gaaaaaagct gttaaaatac ccattacgcc
      781 taaaacagca tatgcagctc cgtaaaattg taggaatcct tgatttttat catttttgtt
      841 gatcaataca aaaaagatat cctgtttatt aaataaataa tagctaacga ataataatac
      901 taaagtggcg ataatcatta aaatcctaat catgaacaaa tcctccaaaa taagcaacaa
      961 atagaaaaag caatttgcca agagcaaatt gctttattct ttaaaagatg gtaatctccg
     1021 ttaatgccgt tgtttgtcct gtagtattga tcccgcgaat tcaagcaggt gggtcccatg
     1081 gtcgtagctt cgaactacca aatgataagg catgttacca gcagtgacac aagacgggtc
     1141 ccaagatatc aataaaaatg ttcggtcaac acacaaagag gacaattcga acatcacaga
     1201 tttcccacct ctatagtagc atatgaattt aaaaagagca atgagagagc tcgcagaaac
     1261 agaaccgttt tcttgtctag ttttttggag gatgcttttt ccactctttt atacggtaat
     1321 actgttgacc cagagcctgt tcatatttcc ctgtatcttt tggctgataa tactgagcat
     1381 tcttcagttt atctggtaaa tattgctgat tgacccaagc ctgatcaaaa tgatgaggat
     1441 actgataacc cacgccacgg ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat
     1501 gatcaggaac atctccagct ttgccctctc gaatatcagc aagtgctgca tctaatgcca
     1561 tgtaggcaga attggatttt ggcgacaagc aaagatcgac gacgacgtct gctagtggga
     1621 tacgtgcctc aggcaatccc aatttttcag cagctaatac agcgttcact gtacgagccg
     1681 cagcagcagg attacctaaa cctatatctt cataaccgat aaccatcaga cgccggcaaa
     1741 tacttgccag atcacctgcc tcaactaaac gggcgagata atgaagtgca gcatccacat
     1801 cacttccacg aatcgatttt tgaaaagccg aaataacgtc ataatgagca tctccatttt
     1861 tgtcatgggt aagagctttt ctttggacac attcttcaat gatcgacagt gtaagatgaa
     1921 tccttccttc tttatctgaa ggagtcgata gtgtagccag ttccagccca ttcaatgcac
     1981 tccgcaaatc gccgttcgtt gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga
     2041 ttgcttgttg tccaaggccg cgttctttat cccttaaagc atgttcgact gccaactgga
     2101 tgtcttgttc tgttaatggt ttgacttcaa agatctgtgt acggctgcgg atcgctggat
     2161 tgatggtaat ataaggattc tcagtagtcg ctccgatcaa gatgattcgg ccactttcta
     2221 aatgaggaag cagaaaatcc tgttttgttt tatctaatcg gtgtacttca tccaataaga
     2281 ggatcactgt accactcatt tttgcttctt ccgctacaac ttgtagatcc ttttttgaat
     2341 ctgtagcggc gtttagcatg cgaaatgcat aattagtaga gccggcgatc gcacttgcga
     2401 tactcgtttt tccagtacca ggaggtccat atagaatcat ggaagagagc atgcgagcat
     2461 cgaccatgcg gcgtatgatt tttccttccc cgactagatg ctgctgacca acgacttcat
     2521 cgatcgttcg aggtctcatg cgataagcca atggctgttg cataggattt tcctccttct
     2581 tgtttttacg tcccttaatt atatcatatt tagcaagatg cctagaaaga acagccttct
     2641 gttgttttgt tttcatagct tatccaacta atattgtgta tgataaagta ggtgagaaaa
     2701 atgacggata aacaaaagat agatgaattt ttttggaata aaacgacgcc agaagtggca
     2761 cgggatttat tggggatgta tttggagcat gacacaccag aaggaagatt agctggatat
     2821 attgtagacg cggaagcata cctaggtcca gaagacgagg ccgcccatag ctatggttta
     2881 agaagaacac cgcgtgtgcg ggcaatgtat gaaaaaccag gtacgatcta cctttacacg
     2941 atgcatactc atcggatttt gaacatcatt actcagccag aagggattcc tcaaggagta
     3001 atgatacgtg caatcgaacc cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga
     3061 aaaactggtc cagatatcag caacggtccg ggaaaattag tggaagcatt agcaattcct
     3121 caagaacttt atggtcagtc tatagcagat agttcgttac gcttagtttt tgagaaaaaa
     3181 aagacaccaa aaaagatcaa tgctttgcct agaatcggta tcccaaacaa aggtgtatgg
     3241 acagaaaagc cgttgcgttt tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa
     3301 aaccaaatcg agaaagattg gggttggagg aaagaaaatg aaaaagaagg atctattaac
     3361 atatttagat gaaataattg aaaaacaagt gacagactat gatgtagctt tagattggga
     3421 tacaaaaaat catacgatcg agatcgttgt tcgcttgttt gcagaaaata aagcacaatt
     3481 tgagattgat gatgcagaag ggatcgtttc gcaagaacca attatcgaat ttgaagacgg
     3541 cgtacttctt tttaatcctc agaaatctgt ttttgatgaa cgcaattatc tagcagtaat
     3601 cccttatgaa ggaaaaaaag ggttggcaaa atcagtagct gattctttag tggaatatct
     3661 aaatgaagta ttagctcaag ggcaaagcga tttgcttgat tttttggatg aagacgatga
     3721 cgaagctgta ttcgagcttc actgggataa tcagcaacta gcagaattag tagaagtaaa
     3781 acagcaaaat gaagcagata cttatttacc gtacccaagt tattaaggag tgacagatat
     3841 gaaatggaat gaagtaaaag tagaaactga aagtgaagca gtcgaagcag ttgctaatat
     3901 tttgatggag gcaggggcga gtggtgtcgc gattgaagat tctttagatg ttgaacattt
     3961 tcagtcggat caatatggtg agattttaga taaaaatgat tttacatcgc tgaaagaagg
     4021 cgcactagtc atggcttatt ttccggaaac gactttctta ccggaaatct tgccttttat
     4081 caaagatcgt atcacacaat tacctgagtt tggtctagct attggaaaaa ataaagtaac
     4141 agttagtgaa gtagaggaaa gcaactgggc aacagcctgg aagaaatact atcatccggt
     4201 gcgtattacg cgaatgctga cggttgcgcc aagctgggaa aactaccaga cagaagatcc
     4261 tctagaaaaa attatcacac tagatcctgg tatggcattt ggcacaggca ctcatcccac
     4321 gacttccttg acattgacag cactagaaac agtcttgcgt ggtggtgaaa cattgctaga
     4381 tgtgggaact gggtcgggcg tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt
     4441 ctatgccttt gatttagacg aagtagccgt tcgttcggcg aaagaaaata tggatatgaa
     4501 tgaaatagcc aaagatgtcc atgtatcagc taacgatctt ttgacaggaa tcgagattga
     4561 aagtgatgta atcgttgcga acattttagc agatatcatc ttattgatga tcccagatgc
     4621 ttggcgttta ctgaagcaaa caggcacgct gatcgtttca ggaatcattg aagagaagaa
     4681 gcaaatggtt ctggatgcca tgttagaaca agggtttatc gtggatcaaa ttttccagca
     4741 aaaagactgg tatgcaatta ttttgaaaaa accagaggtg gaatagatgc agcggtattt
     4801 tttaaaagaa tcatatgaat caaaagacta ttttgtttta gaaggggaaa actatcacca
     4861 cattgtacgg gttatgagga tggaacccga ggatgaagtt tttttggcat tcaatgatca
     4921 aatagccatt gttgcagaaa tcacggagat tactgaagag gctgtttatc tgaaagaaat
     4981 taaaaaagaa gaaaatcaaa aggaactgcc aagttcgatt accatagcga gtggctatcc
     5041 taaaggggaa aagctggatt ggatcgttca gaaatccact gaattaggag cgcaagcttt
     5101 tcttggtttc ccggcatcag cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg
     5161 acaacaacgg cttgaaaaga ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt
     5221 gccatcagta gagttattgg aaacgaaaca agatttattt gagcggctag atgattatga
     5281 cgtggtcttg gttgcttatg aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa
     5341 aattcttagt gaaacaaaac cagatagtcg aatcttagct gtctttggac cagaaggtgg
     5401 attatcccgc gatgaagtcg attattttgt agaacacaaa gggatacttt gtggattagg
     5461 accaagaatc cttcgtacag aaacagcacc tctttattta ttaagtgctg ctagctatca
     5521 atgggaatta atgaatcctt ctttcagcta acgttcttca ttaataaaag agtatcgaca
     5581 gaaagaattg aaaaaatagt caacaatttg tataatagaa acaattattt atacaatgga
     5641 tacgaaaaat cgtttgaaaa agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa
     5701 ctgcacggat tttgggacaa ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa
     5761 aaaagaaagg gggatcgatt cctgtgacaa aagaagaaat tttaacggga cccggtgtca
     5821 taaagctcgt tagtcaatac atgggtcccg aacatgtagc atttgttgag aaagcatgcg
     5881 aatacgcgac tgctgcacat gacggacagt ttagaaaatc aggcgaaccc tacattattc
     5941 atcctatcca agtcgcaggt atattagcag atttaaaaat ggatccccat acagtggcta
     6001 caggcttctt acatgatgtt gttgaagata cagaaatcac tttagaagat ctgagagaag
     6061 aatttggcga tgacgttgct atgttagtgg acggcgtaac caaattaggg aaaataaaat
     6121 ataaatccca cgaagagcag ctagcagaaa accaccgaaa gatgctgcta gcaatggctc
     6181 aagatttacg agttatcatg gtcaaattag ctgatagact acataacatg cgtacgttga
     6241 agcacctgcg agaagataag caaagaagga tcgctcagga aactttagaa atctatgcgc
     6301 ctcttgcaca tcgtctaggg atcagccgga tcaaatggga attagaagat acagcacttc
     6361 gttatctaaa tccaaaacag tattaccgta tcgtccactt gatgcagacg aagagagaag
     6421 aacgtgaaaa atacgtaagt ggtactgttg aagatattcg aatagcgaca gaagagctgg
     6481 ggatttttgc agaaatctat ggacggccaa aacacattta ttcaatctat cgtaaaatga
     6541 aagatcagaa aaagcagttc aacgaaattt atgacttgct agctattcga gtgatcgtag
     6601 attcaatcaa ggattgttat gctgtattag gagcaatcca cacaaaatgg aaaccaatgc
     6661 ccggcagatt taaggattat attgccatgc caaaagctaa tatgtaccaa tctttgcata
     6721 ctaccgtgat cggtccggca ggaaatccgg tagaaattca aatccgaaca caggaaatgc
     6781 atgaaatcgc tgaattcggg gttgctgcac actgggccta taaagaagga aaaaatgaaa
     6841 aagtagaacc agatggtatg acgaaacaat taagctggtt ccatgagata ctcgaacttc
     6901 aagacgaaag ctatgatgct tctgaattta tggaaggcgt aaaaggagat atctttagtg
     6961 ataaagtcta cgtcttcaca ccaaaaggag acgttactga gttaccaaaa ggatccggac
     7021 cattggactt tgcatacagt atccatacag atatcggtaa caaaaccact ggtgcaaaag
     7081 taaatggcaa aatggtgcag cttgattaca aattgaaaaa cggagatatc attgagatca
     7141 tgacttctcc aaattcattt ggcccaagtc gcgactggtt gaaattagtt gctactagca
     7201 aagcaagaaa taagatcaaa cgtttcttca aagcccaaga tcgagaagaa aatgtgatca
     7261 aaggccacga atccgtggtc aaatgtatta cagatctagg atttacgcct aaagatattt
     7321 tgacgaagaa caaactgcaa gaagcactcg atcgttttaa ttatcaaaca gaagatgatc
     7381 tctatgcagc tgtagggtat ggagaagtta gccccttgac gatggccaat cgtctgactg
     7441 aaaaagaacg taaagaacaa aaaatcgagc agcaaaagca agaagcagaa gaaatcatga
     7501 atcagccgaa aaaagaacct gacaaaatga aagtacgtca tgaaggtggc gttgtcattc
     7561 aaggggtaga aaacttacta attcgtatca gtcgctgctg taatccgatt cctggtgatg
     7621 atatcgttgg ttatatcact aaaggcagag ggatatccat tcatcgtcga gattgtccga
     7681 atgttcagcc tgacaaacca aatgtagcag aacgtttgat tgaagtcgaa tgggaagata
     7741 catcgaatac acgaaaagag tatgatgcag atttggaaat ttacggctat aatcgttcag
     7801 gcttattgaa tgatgtactt caaacagtca atgcgctaac gaaaaatctc aacagcgttg
     7861 aagcacggac gaataaagat aaaatggcga cgatccattt gacggttggt atccagaatt
     7921 tatcccacct aaagagtatc gtggataaaa tcaaagcagt acctgatgtc tacagtgtac
     7981 gccggacgaa tggataggag gacagatatg agagcagttg ttcaacgggt aagtaaagct
     8041 gctgtgtcag tcgatcagca agaaattgga aaaattggct acggcctact tgttttatta
     8101 ggcattcatg aaaccgatac gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa
     8161 atgcgtattt ttgaagatga acaaggaaaa atgaatatta gtgtagaaga tgtgggagga
     8221 caaattttaa gtatctctca attcacactg tttgcggata cgaaaaaagg aaatcgacca
     8281 agctttgtgg aagccgcacg accagaaaca gctattcctt tatacgaatc attcaatgaa
     8341 ggaatcagaa gtcgcggcat cacagtcgct accggacaat tcggagcaga tatgtcggtt
     8401 tctctcgtca atgatggacc tgtaacgatc attattgatt ctaaaaacaa ataaagtaat
     8461 ctggttttca ctagtaaaaa ctatgaaaca cgtcgcttaa gttagactga taaactctaa
     8521 cttaagtggc ttttttgtct gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt
     8581 aagcttaaat tatacaagtt attttttata ggaggttgct gaagatgaaa gaagtaccag
     8641 tagtagatat caaaatcaca gatttaaaaa aattgtatca aaaaggatac aacatgttgg
     8701 aggagttacg ccatgaagcg gacgctcccg tcgtcaaagc aaagattttc aataaagaag
     8761 ctatcacgat ctacggatca tcagcagcaa aagtatttta tgatccaagg aatttcaaac
     8821 gaaaaggtgc tatgccaaaa ttagtattga agacactttt tggtcaaggt ggagtacaga
     8881 ctttggatgg agctgctcat caccatcgga aaaatatttt tatggatcta atgacaccgg
     8941 aaagaatgga agattatcat cgtatcttag ataagaatct gacacaagca cttgaagcac
     9001 agcatggtca atttgaacta tttgatttaa gtaagatggt tttctttaca tctatttgcg
     9061 agtgggcagg tatcaattta tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat
     9121 atcaaatctc tatgatcagc ggaacgttta cttctccgat tgatcacata aaaggtgtcg
     9181 aaaatcgcaa aaaatcagaa aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc
     9241 ctgtggctgg aaaagaaaat gtggcattat atgcttttgc caatgccaca gatttagatg
     9301 gtcagctttt acctctggaa gtggcagctg ttgaattatt gaacatcatc cgtccaacgg
     9361 ttgctctaac tgtgtgggcg gcattgatgg gacatgcact tttcagtaga ccagatttgt
     9421 atcagcaatt aaaaaatgac ttttcgacgt tacaagatcc gtttattcaa gaaatgagac
     9481 gctattatcc tttcttccca atgctacctg cgatttcgct gaaagaagta gaagtagatg
     9541 gttatcgtat accagaaggc agttgggtta ttttagattt atatggaaca gaccatgatg
     9601 aacgaacagt tgaagcgcca gattccttta tgatcaaacg gtatgtaggg aaagcaaaag
     9661 atatttccta taaagaagaa tatgagatga ttgcacaagg cgggggaaat tttcgacaaa
     9721 tgcatcgctg tgcaggagaa tggatcactc ttcatagtct acgtgtgttt tccgatcagc
     9781 tagtaaataa gtttgagttc tctgtacctg aacaagattg gacgattcca ttcaatcagt
     9841 ttccgactta tccgaatagc cgagcgctac tttacaagaa ttagattagc ataaacttat
     9901 cgaaaaaaag gaagatcaaa cagtgctgat cttccttttt tcatattact ataaattgat
     9961 aaggtcaatt gatcaaaatc cacgaaatgc ttcatcaatg gtttgataat cttcattgga
    10021 taaatgcaaa tctaaagctt ggacattgtc agatacttgc tctggacgct tagctccagg
    10081 tataactaca gacactcgtg gattcttcat gtaccaagct aaaacaagtt gcgcaggagt
    10141 ggcttggtat cttttagcaa tggggcgaag tacatcgaca gcggttaaaa tttctctgaa
    10201 acgttctcct tggaaatctg gatttctttt tcgaggatct ccttcaccaa attgtttttc
    10261 ctcaccaagt tcatattttc ctgtcagcaa accggaagca agaggaaaat agggaacaaa
    10321 actgattttg tttttttcaa gataagggaa taattctttt tcagcctgcc gatggatcaa
    10381 actgtattta tcttctacta catcgacata tccatctgca ttcgcttctt tcaattgttc
    10441 taacgtgaag tttgacacac cgactgctcg gatttttcct gcttctttta attcgtgcaa
    10501 tgtagcaact gattcatttt ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc
    10561 gatgtaatca gtttgcagac gttttagtgc atcttccacc gattgtttga gaaactcagg
    10621 agaattatca aatgttcgcc ctttatttgg tacatgagca gcttttgtag cgatgacgac
    10681 acgtgagcga tcatattctt tttccttcag tacctcgcca atcagttctt cggaacggcc
    10741 gtttccgtaa gcataagcgg tatcgatcaa attgatcccg ctattcaaag ctgtacgaac
    10801 tacttgtttt cctgtctcat cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt
    10861 tgctcctaat ccaagctgtt ctgcgtagac ttgtgaatgt ccgattctta tttctgccat
    10921 agctgattcc tcctttttgt ctagtctaaa acaaaatacc aaaaagctga actaaaacgt
    10981 ttttgtgagg ggaaatagtc agatatctct tgactttgag actggttttt agtaggttat
    11041 aagtaatatc gaatgtcaat gaaagagcga gtaagttttt gaaactttac aagagaggat
    11101 catcgaggct gaaaatgatc taaagtttca ttagcctaaa gacactctgg agatggacga
    11161 gtgaaaagcc gtcccgcgta cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat
    11221 taggtggtac cgtgtatgaa tttcattcac ccttgttcat gatgaacaag ggtgattttt
    11281 ttatttacat agctaagaaa gggagagaaa actatgagtt tccaaagacc aaaaggaaca
    11341 aatgatattt tgccaggcga atcagaaaaa tggcagtttg tcgaagaaac agcacgttta
    11401 ttattcagag attatcagta taatgaaatg cgtacaccga tttttgaaca ctatgaagtg
    11461 atatcccgaa gtgtagggga tacaacggat atcgtttcaa aagagatgta tgatttttat
    11521 gacaaagggg aacgccatgt gacgcttcga ccagaaggta cagcaccaat cgttcgttct
    11581 tttgttgagc ataaattgtt cggcccagag tatgcgaaac cgttcaaaac tttttatatg
    11641 ggaccaatgt ttcgctacga acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc
    11701 ggagtagaag catttggatc agaaaaccct gcaactgatg tggagagcat ggtgatggca
    11761 cttgatttct tcaaacagtt ggggatcacg caaatccggc tagtcatcaa ttcattaggt
    11821 gataaagaaa cgcgtcaagc ctatcgtcaa gcattgatcg actatctttt accttttgaa
    11881 tcagagctga gtgaagactc taaacgccgc cttcatgaaa atccattacg cgtattggac
    11941 agtaaagaca aacgagatca aaaatttgtg gcagaagctc catctatctt agattatcta
    12001 agcgagcctg ctcaaaaaca ttttgatacc gttgtttcca tgctggatgc attggctgtt
    12061 ccttatgaaa tcgacagtaa tatggttcgc ggactagatt attacacaca tacgattttt
    12121 gaaatcatga gtgacgcacc aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt
    12181 tatgacaatc tagtggaaga actaggtggt ccttcaacac ctggcttcgg atttgcaatg
    12241 ggtatcgagc gattactctt gactatggag gcagaggaag tagttatccc tgcatttaat
    12301 gagttggatg cttacgtggt cgcactcgga gacgaaacaa atatcgaagc attgaaagtg
    12361 gtccaagcga ttcgaaactt tggtttttca gctgaccgcg acttcatgaa ccgtaaagca
    12421 aaagcgcaat ttaagacagc agataaagcg aatgccaaat tagtattggt gatcggtgaa
    12481 gatgagcttg ctagtcaaac gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt
    12541 tttccattag aagagatata tgaacatttt gatgaagtct atgatgaaat gactttattc
    12601 gagtaggagg aaaaaaataa atggcacaaa gaacgatcta ttgcggatta gtttccgaac
    12661 aacaattaga acaaacagtt acattaaaag gatgggtaca aaaaagacga gaccttgggg
    12721 gagtaatctt tatcgaccta cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg
    12781 aaatcaacaa agaagcatgg gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag
    12841 tgactgggga agttagaaga cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg
    12901 aattcgaagt gattgcaagt gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc
    12961 aaattgaaga tgatcaagca atcagtgacg aaatacgttt gaaatatcgt tatttggatc
    13021 tgcgtcgtcc aaaaatgact aaaaacatca aattaagaaa tgcgacaaca aaagcgattc
    13081 gtcattattt agatgataat gactttctcg atatcgaaac accttaccta gggaaatcta
    13141 caccagaagg cgcaagagac tacctagttc cttcacgtgt ccatgctgga catttctatg
    13201 cgttgccgca atctcctcaa ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt
    13261 attatcaaat cgttcgttgt ttccgcgatg aagatttacg tggagaccgt cagcctgaat
    13321 ttacgcaagt agatattgaa acaacgttct taacagcaga agaaatccaa acttacacag
    13381 agggattgat tgcgaaggta atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc
    13441 ctcgtatgac ctatgatgaa gcaatggctc gctacggcag cgacaaaccg gatacacgtt
    13501 ttgatatgga attgatcgat ctaagcgata cagtcaaaga agtagaattc aaagtcttcc
    13561 aaatggctct tgaaaacggc ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc
    13621 gctactcacg aaaagacatg gatcagttag gtcaatatgt aggacaattc ggagctaagg
    13681 ggcttgcatg gctgaaagta gaagaagacg gattgaaagg tccaattgct aaattcatgg
    13741 gagaagcaac agaagcaatc attaaagcaa cagatgcaaa accaggtgac ttgctgatgt
    13801 ttggcgcaga taaaagtgaa atcgtcgctg ctgcattagg tgctatccgg acacgtttag
    13861 gaaaagaatt aggactaatt gatgaatcga aattcaattt cttatgggta actgattggc
    13921 cacaatttga attttcagaa gaagaaggtc gatatgtctc tgctcaccat ccattcacga
    13981 tgccaaaaga agaagatatc ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag
    14041 cttatgatat cgtcttgaac ggttatgaac taggcggagg ttctatccgt attcatactc
    14101 gtgagcttca agaaaaagta ctagaaactc taggctttac aaaagaacaa atggaagaac
    14161 aatttggttt cttgttaaca gctttagatt acggattccc tccacatggc ggtattgcat
    14221 taggattgga ccgttttgca atgttattag ccggagaaga taatattcgt gaagtcattg
    14281 cctttcctaa aaacggaaaa gcagcagatg tgatgagtga tgcaccaagt atggtttcgc
    14341 ctttacaatt gttcgaattg aatattgatg taacgaatat agaagaatag ccgataaaaa
    14401 ggtaaaaagg atttgtcgaa tacgcttctt ttgacaacct tgatttaatt gaaaaacact
    14461 ttataatgaa gccataacat ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt
    14521 gggcttatca tgattacacg accaagcttt cggtatctat cgtttatgcg ttgatcgcat
    14581 cagtcgcatt gaatttcttt tatcagccag gacatattta ttcaagtggt attactggtc
    14641 tagctcagat tttgacgact ttgtcaaaat cactgatagg attcgaagta ccggtatcaa
    14701 caactttgta tttactgaat atacctttgt ttgtattggc gtggttaaaa atcgggaaga
    14761 agtttacaat tttcactttt atcacagtca ctttgacctc cctttgtatc catattttac
    14821 cggaaacagt cctatctacc gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg
    14881 gactaggtat tgggctagcg ttgagaaacg gcctatcatc gggcggtcta gatatcgtga
    14941 gtatcacgat tcgtaaaaaa acaggaaagt cgattggttc tatttcgatc tacttcaatg
    15001 cattgatcgt ttttgttgcc ggaattctat ttggctggca atatatgttt tacagtacgt
    15061 tgtctatttt cgtcagtgga aaagtaactg atgtcgttta tactaaacaa aagaagatgc
    15121 aggtaatgat cgtaacgaaa catccagaaa aagtagtaaa tgaaatccaa aactgtatgc
    15181 gtagagggat cacgatcatc aatgaagcag aaggtgctta taagcatgat aagcagacag
    15241 tattgatgac gatcgttaca cgatacgaac tgcctctact tagagaagca atgaaagctt
    15301 ctgatccaca agcttttgta agtattgcag aaaacgtcca gatacttggt cgtttctatg
    15361 aggatggcat ttagatcgag tttgacaaaa attcatgaaa tactgctgta gacagacgtt
    15421 cgtttgtctg cagttttttt ctaccatagt agaatcagca aagaaaaact gcttttttat
    15481 ttgaaatttt cttaaagttg aaaaaaagca tgtttatttt tttaaattta tgggatgata
    15541 gaaaaaaata gtagagaaag gacacgattc tacttgctat tttcacttaa tacccgtata
    15601 ttacgaatga aaaaagttta tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta
    15661 aaaaacagcc gctacatcac tgggtttgat gggctccgtt cattagctgt ggtgggtgtt
    15721 atcttctatc accttctgcc aactagtatg aaaggcggct atttgggcgt tccgattttt
    15781 ttcgtcgtat ctggttattt gatcacggat ctgctgcggc aggaatggga acaaaatgga
    15841 aaaatcaata tttggcaatt ttatgtcaga agaatgaaga gactctatcc ggcacttgtt
    15901 tttatgcttg tgacagcttc ggcttatatc actttgtttc agcgagggct gttaaacaat
    15961 cttcgaggag ttgtggtcag cagcttactg tatgtcaaca actggtggca aatcaataac
    16021 ggtttatctt atttcgatcg atttgctaat gagtcaccgt ttacgcatat ctggtcttta
    16081 gcagtagaag gtcaaaacta tttggtttgg ccgatcttgt ttgtattgtt gatggtattt
    16141 gttcgtaaaa gaaaatggat cttttatact gtgttaggta catccttcct ctccgccatc
    16201 ttgatgatga tcttgtatac accaggaggc gatccaaccc gtgtttatta cggtaccgac
    16261 actcgtctgt tttctatatg gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt
    16321 ttaaagaaaa acatcccgaa acaagcgaaa aatattctga atatcgctgg aggaatctcg
    16381 cttttggcac tgattctttg cttcttcttt ttagatgatc attacaattt catctattac
    16441 ggaggaatgc tcctagtgag tctgttatgc gtagtgctag ttgcagtgac agcacacccc
    16501 ggagcaagtt tgaatcgatg gctgacaaat ccagtattta cttggattgg caaacgaagc
    16561 tatggcattt atctgtatca gtttccagtt atgatttttt atgaagcaaa ggtgactgat
    16621 attgccgatc atgttttgtt gcatacttta gtggaaatca cattgattct aatcatcagt
    16681 gaactttctt atcgatatgt ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc
    16741 caagtgatga aaggatggtt cagcaaaccg atcatcagta agagcaaacc atgggttgtt
    16801 ccaggcacat tacttgtagc aattgcactc gttggtttcg ttacggcacc gaaaaacgct
    16861 gtaacagccg atcaaaaaca actgcaggca aaaatcgctg aaagtaaaaa attagcagaa
    16921 gaaaccagaa acaattcaga aaacaccact agttcggttg accaagcgat ccttgataag
    16981 tacgagttgt ccaaggcaca agggaataag gcacaaaaat tagaactaac ggcatttggt
    17041 gattcagtta tgttggatgc tgcaacggat ctacaagaac tttatccaaa agtagtggta
    17101 gatggagatg tcggacgaca attatatgcc agtgtaccgt acattgaaaa attaaaggaa
    17161 caagatttgt tgaaagacac tgttctgatc ggactaggaa cgaatggctc attctcggaa
    17221 gctcagtttg atagtgtgat ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc
    17281 cgagtaccga cgaagcgctg gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa
    17341 aaatacgaca atatgacgct gattgattgg tacagctaca gtaatgacca tagtgactgg
    17401 ttttatgatg atcaagtcca tccaaatcct gaagggatga cacattacat tcacttagtc
    17461 agcgaagcct tgctaggagg aagttcaagt acgaacagca gtgagacaaa cgtgacagaa
    17521 tgatagctac aaaaaacttc aggcaaaaac atttgttttt gcctgaagtt tttttatatt
    17581 taccgtgttt ttaacattca tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa
    17641 taacgttctt tttgttttcg ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg
    17701 cttcttgaag aaaatacttc tgcatggatc atcttaacag gtcttctttt ttgaagacga
    17761 gtatatttag caccagtacc attgttatgt tcctctaatc gtctagaaag atcggttgta
    17821 tatccaccat aaaatgtctg atctttacag aataatacgt aaaaataatg ttcatttgcc
    17881 atagagcatc tcacgaatct ctgcagtgta ttctccatcc atattgtaag tgatcaatgg
    17941 tggagcgact ttgaatccgt ctaatttgcc ttctttgatt ccttcaacta acaaaatatt
    18001 tgcctctttt ccaggttttg ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc
    18061 ttccatgacc tgaatgattt ctaagaaccg atcaggacga tggaccatag taaagcgtcc
    18121 atttgttttt agtagcttac ttgaaatatc gatcacttct tctaacgtcg tatgaatctc
    18181 atgacgggcg attgccaggt gtttattagg gttcgtttta tttgttggca gccctttgaa
    18241 ataaggtgga ttacagacga ctaagtcaca agaattatgt cgaacgacag ataagctgtc
    18301 tttcagatcg atggtgtgga cagtcatttg ttcatttaaa tggttaagcg cgatactacg
    18361 tcttgccatg tctgctagac gaggttgaag ttcgatagcg tcgatagccg cctgggttcg
    18421 tttacttaaa aaaagtccaa ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt
    18481 tttaggtaca cgggaaaagt gagcaagcag cacagcatct aaagaaaaag aaaacacttt
    18541 ggaactttgg ataatcttga tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg
    18601 aagcatggat tccctccaaa atgaaaaaaa tagtcgtctg tattatacta tttttattaa
    18661 aaagaaccaa ggtggcttgt caaacctcta ttttttatgc atactatgac cataagaagg
    18721 gaaaggaaga gactatgttt tatcgattta tgcgcggggt agttcgagta ctattagcct
    18781 tagttaatgg aaatgcccgc tatgagaata aagaagtttt accgcaagat gagaattaca
    18841 tactagttgc tccccatcgt acttggtggg acccattata tctggcggta gctgcagcac
    18901 ccaaggaatt cagctttatg gcaaaagaag aactgttcaa aaatccagtt ctgcgattta
    18961 tattaactcg atccaatgct tttccagtta aaagagaaaa tccaggacca agcgtcatta
    19021 aaacacctgt aaagattttg aaatcgacaa atttgagttt gatcatgttt cccagtggga
    19081 caagacatgc tacagaactt aaaggcggaa tggcattgat ttccagaatg tctaaagcga
    19141 aaatcgtgcc agctgtatat caaggtccgt tgacacttgg ggatctgttc aagcgtcaga
    19201 gagtgacagt gcgtttcggc gaaccaatcg acttatcaga tatcaagaaa acggataaag
    19261 aaggtatggc ggagatcgaa cgacgaacac aagcagcttt tgacaaattg gacaaagaag
    19321 tgaaccctga tttcaaatat gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc
    19381 ggtcttttga atctactgtc ctgttcagtt cagacttttt caatgaaaac gagggagaga
    19441 cgtcaagtct gccctctttt tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa
    19501 tggatcaaag tgttataata attagaagga cattttttga ggtgattgaa tgcgtttttt
    19561 acatacagcc gattggcata tcggaaaaaa actacaaggt tatgacttga ttgaagacca
    19621 gcgtcatgta ctatcttcta tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt
    19681 gattgccgga gacttatatg ataggagtgt cccagctgtt gatgccgtag aattatacaa
    19741 tgaattgatg gtcgattgga atttaaagga aaagatcccg atttttgcta tatcaggaaa
    19801 tcacgatagc agtacgagac tttcagcggg tacgccatgg ttcagttatt cgaactattt
    19861 tttgcgaaca cagctagcag aagcatttga accagtcgag tttaaaaacg tacaattttt
    19921 ctttcttcct tactttgaac caattgcagc gagattatat tttgaagatg acaatatccg
    19981 aacgatcaag caagcggtag ccaaggtgat agataaaatg caggagctat ttgattcaga
    20041 aaaaaaacaa gtattgatta gccatttttt tgtaatggga agtgtaaaat ctgattcgga
    20101 aacgaaaatc gaagtaggcg ggttggattc gatccctggt gaactactta caccgtttga
    20161 ttatgtagca ctaggacatt tgcataatca agctgctttg agacaggata atgctcgcta
    20221 tagcggttcc ccattgaaat tctctttatc tgagatcaac caaaaaaaag gcgtatggat
    20281 cgttgacctg acaacaggcc tggagttgaa ttttagggag atcgaacccc tgcatgatat
    20341 tgaagaaata acagcgagtt tcaaagaatt gctggatcct gccttttatc agtccgtcaa
    20401 tcgggagaat tacatctata tctatctcac tgatagaacg atcatcccga atatgatgaa
    20461 ccagcttcgg caaatatatc ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga
    20521 acaaacaaag cgcaaacgaa aagtactaga aatgaaagat cctcaaaaat tagcagaagc
    20581 attttttagt gaaatgacgg aagagcagct aactgcaaac caagaaaaat ggctcggaga
    20641 aacgttgcaa gaaatcatgg aaatggaatg atcaagaatg aaaccgaaaa aattacaact
    20701 taaaaatttt ggtcctttta tcaatgagac cgtagatttt tcacgtttga cagaagcacc
    20761 gctttttttg atcagcggga agacaggagc tggcaaaacg acgatttttg atgggatcac
    20821 cttcgcactt tttggtgaaa cttccggaag acttcgctct ggaaaagaga tgcgttcttt
    20881 gtttgctaca ccagacgaag aaacaagcgt gactttttct tttgaacatc agcagatgag
    20941 ctatgaaatc gaacgaaaac cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa
    21001 aaaacaggca gccaaagtaa cgttgaccat ttttgatggg aaaggaaaag aaataaaaca
    21061 aatcacaaaa cgtacagaag cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa
    21121 acagttttct caaatcgttt tactacccca aggagaattc cgtaattttt tggtttcatc
    21181 aagcagtgat aaagagactg ttttacgtca tttattcggt actcaatttt tccaacagtt
    21241 caatgagcga ttaaaagaaa aagcaaaaca acagcaacaa aaattggatc atttagagca
    21301 agagctgcat cttctgcaaa aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg
    21361 gtttgaagcc gttttagccc aatggacaaa ccatcaggca atactcgaaa aacaaatcac
    21421 ggaagaaaaa gaagctctaa cggaacttca ggaaaaacaa aagcaactag aaaattccta
    21481 ctatcgtttt gaaagcttga aaaaaagtta tgaagaaaaa acgatattaa taaacaagca
    21541 aaaggaatta gctgctcaaa aagacgaaat agaggaaaag aaacgatgga ttgggtatta
    21601 tgaatttacg caacgattag tcgaaccaat ccagcgccta caagaaataa aagttgaaaa
    21661 aatagaactg tcacaaaaaa gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa
    21721 ttatgaagag tggcaaaaaa atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga
    21781 agctgctcaa aaactgcaaa acaaacagat gatggtgcca attgtcgaat ccttacgtag
    21841 taaaaaacaa gacgcagaac aattaacaat ttcattggat aaagaagaat tgaatgccga
    21901 gaagctgtat caaaatctcg ctatctatca ggaaagaact cgaattcttc aagaaaattt
    21961 actggatcag gaaaaactgc aagaagatcg tcttgctttt ggacagttaa aatatctaga
    22021 tgaaaagcag caagaaatag aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat
    22081 aagagaagaa ctcaaaaaag caactgaaga aataacaaaa aatagtcagc tattgaaaga
    22141 acagacagaa caagcagaac agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct
    22201 tcagcttttt ttgcgtccag gggagccatg tcttgtttgt ggatcaacgg aacaccccat
    22261 acaacaatta aaacacgaac agccaaataa ggaagatatc ttaaaagtag aacaacaact
    22321 ggcagaagct gagtctgctg tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca
    22381 tgaaaataat cttcaacaac aattatcaga tttagaacaa aaaatcatgg caacgaatat
    22441 acaattggct gaacaagaag aacacttgca acaggctttg aaaaaggcat ttcctgagat
    22501 aacagaacaa aaaacaaaaa caactcttgt agtaatcgaa caatctttag atagacgaaa
    22561 aagcaagatg gccaatgcaa gaatagagct ggaagaaata agacaacaag cagaaaagct
    22621 cgaacaacaa ttagctgtct acaaacagca gcagacagaa aaaaataatc agctccagca
    22681 actgcaagga gaaatcaaaa gtttagaaca acaattgcaa gatacggata gtaactgttt
    22741 agaagaggag atacgacgac ttgaaaaaca gttagaagaa gactcgaatc aactagctgt
    22801 tgagcagaaa gcaggagtgc aattgttgca agatcttcat acgcttcgga cacagcttga
    22861 tcttcaacat gaacaaatag aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat
    22921 agctaaaaag ttagaaagcc agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc
    22981 acaacagcaa gcacaatata aagaaaacca acgtacagtt acttcttatc atgaagagca
    23041 attagtgaca gctgaccggc tgcgtcaatt agaaaatatc cagctaactg agacattccc
    23101 agatacagaa gagatcagcc aacagttaga agaaataaga cgtatgatcg aaataaagca
    23161 agaaaagata tacggtttac aagaacaaaa aattagtaat caaaaaatct acgatgaatg
    23221 tctttcgatt tatcacacaa gccagacgaa attagatgag cttacgcaat tacagcagct
    23281 ttcgcaaaca ttcaacggag aaaatcctaa gaagactagt ttggaacggt atgtgcttca
    23341 ggtttatctt caagaagtgt tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa
    23401 tcgttatcaa tttgagctag cggataccat tggcagttat cgagggaaaa ccggattaga
    23461 aatcaatatc tatgatgatc aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg
    23521 tgagagtttt attgcagcac tttctttagc attagctctt gccgatgtga tccagacaca
    23581 agctggtggt gtagcaatcg atgcattgtt tattgatgaa ggatttgggt cattagatga
    23641 agaagctttg gaaatggcaa tggaagcttt agaaacgatc gaaagtgaag gaagaatgat
    23701 cggcatcatt agtcatgtaa gagaattgaa agaacgagta ttacaacaaa taagaattga
    23761 tacagaaggt agcggacaaa gcaaaatacg ctatcaactt ggataaaaag ggagattggt
    23821 aactatgaaa tggagtattc cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga
    23881 aggccgagtg ttatcggttg tccctgacca agaagaaaac gtgtggcatg cagaagtctt
    23941 gggcagtgaa ttgtatatgg ttgatttgga tggtacagca aaagagatag attactgcca
    24001 atgtccctat tgggaggaac ataaatattg taagcataca gttgctgtgg aactttattt
    24061 acggtcgaaa aatctatctc gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa
    24121 agcaacaagt gagggagaaa tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa
    24181 tcctcaagcg gtgcaacctt tgattattga ataccaagta gaaacgattg agactaatca
    24241 gtatcaccca gagctttcta ttttggcact ttacttgcgt atcggttcat tggcatcacc
    24301 gaaaaaaaca tatatcgtaa aaaacatcta tgatttttta caagcttaca cagaaaaaga
    24361 aacttacact gttaataaac agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga
    24421 agatcaaaaa atactcacgc atcttgcagg aagtgctcag acgcatcaat tattaggtac
    24481 gaacggctta caagtcaaag gaaaactaga taaaagatat ctgcttctcc cagtagaaca
    24541 agcccgcttc ctgttagagc agatgaatca gactacacgt ttgcatctgc agataaatga
    24601 acaaaacgat caaggaatac aattttccga tcaaaacaaa cctttatcat tcaaagtgga
    24661 aaaatttgga gaagattatt tgctgcaagc attgaatgat tttgattttt tctttatgca
    24721 ttatcagtgg ggagttatcc aagggacatt ttattctctg acgaaatatc aacaaacggt
    24781 ttatcaaact tggaaacaat tgattcgccg attggagaaa ccagaagtag tgttcaagaa
    24841 aaaagaatta ccgtctttgt ttaaagagat tatccctctg ctgtcagaga tcggcgacgt
    24901 agctattgcc cctgcagtag aagaggaagt agcagatatc cccgtcgaat ttattttctt
    24961 tttccgaaaa gcaaaaggaa aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat
    25021 ctattcgact gacccgaagc atgaggtctc gacagaacag gcttttcagg tgttacgtga
    25081 cacagtagaa gagaaacgag tacttgatct attcagaatg tatcgctacc agaaaaatga
    25141 aactggttat gaacgtccat tgccaagcgg ggaagaacta tatgcctttt tccgcacaga
    25201 actatctgtc ttccgtcagt ttggtgaagt cagacttgga agaaaattgc gagagttgta
    25261 tttagatgcg cataaacatc aaccgaaaat cgaagtaacc gagaccggtt catggctcga
    25321 tattcgattc gatgtgacag ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt
    25381 gctgagaaat gatgcttttt atacattaga aaatggtcag gttctttctt ttgattcaga
    25441 agaatttcaa caaacaagcc aagtgttgca acaattacgg gaatcgatac gtacagaaga
    25501 aggaacgatc catgtaccta aaaatcaagg attgatcatt caaaatcaat tggaaaaaag
    25561 caatgctact tttagtgaat cgttccaaac gatggtacaa gatctcattc atccagaaag
    25621 ataccaggca cagcttccca aaggattgaa tgcaacgatg agagattatc aaaagcaagg
    25681 ttttcgatgg ttgaagatgt taggtcatta tcagtttggc ggtattttag ccgatgaaat
    25741 gggacttggg aaaacactac agacaattgc ctttttactt tcggaaaaag aagaacggaa
    25801 aagcttctct gctttgatcg tagcgcctgc gagcttaatt tacaactggc aggcagaggt
    25861 gagaaaattc gccccttctt taagtatcca agtaatcaat gggaataaaa aagaacgtga
    25921 agaattactg gctaaagaca cagatatccg agtgacttct tatgccagct taagacagga
    25981 tctagctaat tatcagtcgc aaaaaattga ttatttgatt cttgatgagg cacaaatggt
    26041 caaaaatagc agtacgaaaa ctgcacaagc attgagagaa ttagctgtac ctcagcggtt
    26101 tgcactgagt gggacaccaa tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac
    26161 gattatgcca ggatttttcc cgactaaaac aaaattcagg gaacttgccg cagaagaaat
    26221 tgcgcaaatg attcgaccgt ttattttacg gcgagataaa caaactgtgt tgaaagactt
    26281 gccggaaaaa acagagatga atctatattc tgcacttaca gaagaacaaa aaactgttta
    26341 tttagcttac ttgcgtcaaa tgcgtgaaga aatcacatca atggattctg aagcattcaa
    26401 gaaaaaccgg atcgggatac ttgctggtct gacaagactg cgacaaattt gctgcgatcc
    26461 tcgtctgttt attgaagatt accaaggcgg ttccggcaag ctcgaacaag taaaagatct
    26521 actggtagct gccaaagaga acaaacgaag agttttgctg ttttctcaat ttacagggat
    26581 gctgactatc ttgcaagaag agttagccga gctagggatc tcgacatttt atttaagagg
    26641 cagtacgaaa ccacaagatc ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga
    26701 tgtttttctg atttccttaa aggctggggg aactggattg aatctcacgg gagcagatac
    26761 ggtcatcttg tatgaccttt ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc
    26821 acatcggatc ggacaaaaaa atgtggtaga agtgtggcgt atgatctctg aaggaacgat
    26881 tgaggaacgc atggattcac tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca
    26941 aggtaatgaa gaacagttga cgaaactgac tgaagaagac atccgcatga ttttaagtgt
    27001 aggagaaatc gaggagtaag agactcgaaa aagcgttcag taatgggtaa gaaagccttt
    27061 ctaaagaagc gattgtttat ttgatttaaa aaatagcaag gaggctggga ttccatttta
    27121 tcccagcttc cttgctatca tttttttatt tctattttta aaggttatac aaagattgtc
    27181 ttcattgtct ctaacagctg atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt
    27241 tcaattttgc gttctcgatg gttgaaccaa agcgcttgcc agttagcact ttttgcacct
    27301 agaacatcat tgtcgtaatt atcgccaacg tataaggtct cttctggaag catatgaaat
    27361 tctttctcag ctagctgaaa aatctctttt tctggttttt ggaaacctgt tgcttgagaa
    27421 atgagcatat tgcgggaagg aatccaattg ttcaattgaa gttgcttcag tttttttgtc
    27481 tgatggtcag tcggcccatt tgtgataatt cctaatggga cattcttttc cttcaagaaa
    27541 tcgagggttt ttttgacctc ctcatgcaag cagatattat caagttcttc ctcgtaaatt
    27601 ttttgaaata agaggccatc ttcttccgta atatgagggt agtctaaatc ttttagtgat
    27661 tggctgatcc gatgtgctcg catatattct agtgtccaat ctcctgccat tacttttggg
    27721 aagttttcat cactatgatg gcggaaccgg atatatagtg gatgcatatc tgcatctgaa
    27781 acaagcggaa cgactctttt gaccgcgttt cgaaatggct gctgctgatc atacatcgta
    27841 tcatcaacat caaacacaac tgatttaatc aaaattttac acgcctttcg gttttcattg
    27901 attttttcac aaatccttga ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat
    27961 aaaggttttt cttactatat ttctatttcc ttgacagaat aaggttttta tatttcagtt
    28021 tttttcacta aaaatcgtga aacacgtcaa taagtttgat gaacaaatta atcattatgg
    28081 tagaagtcga ttgatttatt ttaatgcaat ctctgtggaa ttttcgaaag
//
LOCUS       DADVXV010000032        27806 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.032, whole genome shotgun sequence.
ACCESSION   DADVXV010000032 DADVXV010000000
VERSION     DADVXV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.032"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            1..235
                     /locus_tag="KB969_001295"
                     /pseudo
     CDS             1..235
                     /locus_tag="KB969_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            492..680
                     /locus_tag="KB969_001296"
                     /pseudo
     CDS             492..680
                     /locus_tag="KB969_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            726..1691
                     /locus_tag="KB969_001297"
     CDS             726..1691
                     /locus_tag="KB969_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869295.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            1713..1925
                     /locus_tag="KB969_001298"
     CDS             1713..1925
                     /locus_tag="KB969_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6869296.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            2000..2476
                     /locus_tag="KB969_001299"
     CDS             2000..2476
                     /locus_tag="KB969_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBB6869297.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            2473..4281
                     /locus_tag="KB969_001300"
     CDS             2473..4281
                     /locus_tag="KB969_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6869298.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            4358..4573
                     /locus_tag="KB969_001301"
     CDS             4358..4573
                     /locus_tag="KB969_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBB6869299.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            4665..5528
                     /locus_tag="KB969_001302"
     CDS             4665..5528
                     /locus_tag="KB969_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869300.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            5565..6101
                     /locus_tag="KB969_001303"
     CDS             5565..6101
                     /locus_tag="KB969_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBB6869301.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            6115..6537
                     /locus_tag="KB969_001304"
     CDS             6115..6537
                     /locus_tag="KB969_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6869302.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            6467..8866
                     /locus_tag="KB969_001305"
     CDS             6467..8866
                     /locus_tag="KB969_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6869303.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            8898..10889
                     /locus_tag="KB969_001306"
     CDS             8898..10889
                     /locus_tag="KB969_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6869304.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            10912..11163
                     /locus_tag="KB969_001307"
     CDS             10912..11163
                     /locus_tag="KB969_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBB6869305.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            11153..12382
                     /locus_tag="KB969_001308"
     CDS             11153..12382
                     /locus_tag="KB969_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBB6869306.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            12379..14460
                     /locus_tag="KB969_001309"
     CDS             12379..14460
                     /locus_tag="KB969_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBB6869307.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            14609..18529
                     /locus_tag="KB969_001310"
     CDS             14609..18529
                     /locus_tag="KB969_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBB6869308.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            18530..19474
                     /locus_tag="KB969_001311"
     CDS             18530..19474
                     /locus_tag="KB969_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869309.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            19478..19681
                     /locus_tag="KB969_001312"
     CDS             19478..19681
                     /locus_tag="KB969_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBB6869310.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(19981..20217)
                     /locus_tag="KB969_001313"
     CDS             complement(19981..20217)
                     /locus_tag="KB969_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869311.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(20400..20786)
                     /locus_tag="KB969_001314"
     CDS             complement(20400..20786)
                     /locus_tag="KB969_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBB6869312.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(20768..22096)
                     /locus_tag="KB969_001315"
     CDS             complement(20768..22096)
                     /locus_tag="KB969_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6869313.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(22057..22386)
                     /gene="mobC"
                     /locus_tag="KB969_001316"
     CDS             complement(22057..22386)
                     /gene="mobC"
                     /locus_tag="KB969_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBB6869314.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(22644..23014)
                     /locus_tag="KB969_001317"
                     /pseudo
     CDS             complement(22644..23014)
                     /locus_tag="KB969_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            23159..23344
                     /locus_tag="KB969_001318"
     CDS             23159..23344
                     /locus_tag="KB969_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6869315.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            23502..23669
                     /locus_tag="KB969_001319"
     CDS             23502..23669
                     /locus_tag="KB969_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869316.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            24287..24946
                     /gene="vanR"
                     /locus_tag="KB969_001320"
     CDS             24287..24946
                     /gene="vanR"
                     /locus_tag="KB969_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBB6869317.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            24949..26310
                     /gene="vanS"
                     /locus_tag="KB969_001321"
     CDS             24949..26310
                     /gene="vanS"
                     /locus_tag="KB969_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6869318.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
     gene            complement(26401..27702)
                     /locus_tag="KB969_001322"
     CDS             complement(26401..27702)
                     /locus_tag="KB969_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6869319.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         6947 a         7244 c         7497 g         6118 t
ORIGIN      
        1 gcatggtgat atagatgatg tcagttcgac agtaataaca agagatgatt atgaaaaata
       61 tgatgattcg tacgcgttat ttaaagaaac tttaaaagga gatttgttaa caaaaacttt
      121 tctcttttta ggatttagtt ttacagaccc taatttagaa agaattttat cagatataag
      181 atgggttttg agagaaaacc aaagacctca ttattgtata atgagaaaaa tattatagaa
      241 aaaattttag gttatcgctg aaagccccgg aaatacgggc atttcgcagg atatgagaac
      301 tcaatttact accaatttac tactttcgga ttgagccgca tatatgctga accatactgc
      361 taatacccgc caccccaaat acggcacatc ataaattgaa tacgacaccg taaacgcggc
      421 gttcctcttt cccgtcatgg gagaacagga cgccgctttt ttatgcccaa atagagaaag
      481 gaggcgacgc catgctattt acttccggcc ctgaccgggc gtttgaacgg ctgatgcagg
      541 aaaagcccgg tttcgatcac tacgacggcg gcggggcgga cgcgccggag gattgcggca
      601 cctgccgatt ttaccgcccg gattggaaat atcaattctg ccagtttgca gagtgtccct
      661 atcagccggg caagctgacc gactatgcag cggtcaaatt cacagtgaaa ggagcgaaca
      721 acgctatggc agttttccgt gtggaaaaga acaaaggcta tacggtgatg tcaaatcacc
      781 acctgcggaa taagaacctg accttaaagg ccaagggcct gctgtcgcag atgttgtcct
      841 tgccggagga ttgggactat accctaaaag gactgtccta tatcaaccgg gaaagcatcg
      901 acgcgatcag gacagcggta tgggagcttg aaaaagctgg atatatccgg cgtgagcagg
      961 gccgtgacgc aaaaggcaaa atggccgata tggtctatac catctacgaa cagccggtat
     1021 tggaaaaccc ggtattggaa aatccaacat cggataaccc ggtgttggaa aatccgacat
     1081 cggataatcc ggcgtcggaa aatccaacgc aattaaataa agaagtacaa agaactgact
     1141 tatcaaaaaa agaaaaaata attacagatg gacaaagtac ccattccatt cctatcccat
     1201 ccccgacccc tgcccctatg gagggcgagg cagcggctac gccgccggaa cggaaaagga
     1261 caggaaagga tgaggctgta cggatttatc gggaaatcat tttggagaac atcgagtatg
     1321 cctatctcat tcaggacagg agcattgacc gtgaacagct tgacgaaatc gtagacctga
     1381 tgctggaaac cgtctgcacc gcccgaaaga caatccgtgt cgccggggac gactaccctg
     1441 ccgagctggt gaaatccaag tacatgaagc tgaccggcga acatatccgc tttgtccttg
     1501 actgtctgcg ggagaacaca acgaaagtcc gcaatatcaa acaatacctg cgggctatgc
     1561 tgttcaacgc ccccagcacc atttccaact actacacggc ccttgtcgcg cacgacatgg
     1621 cacagcccga ttggggaaag cctaaatccg gcctgccgga ctattcctgc ggcgagggcg
     1681 aaagcctgta acgagaaaag gaggacgacc ctatgaagca gggcgcattg atttttgacg
     1741 agcgaacaga ccgttacgac atccgctttg atctggccga ctattacggc ggcctgcatt
     1801 gcggggagtg tttcgacgtg atgatcggcg gcaaatggag gcccacccgc attgaaatgg
     1861 ccgaaaactg gtatcttgtc ggcatccggg ccgacgacct ttccggcctg cgggtgcgga
     1921 tttgacctat atctacctgc ggcgtctggt ggttccgcct tagacgccgc ttttgacttt
     1981 ctgacaagga gggatgcgat tgcaggaaga agttactcaa aagaccattg ccctgtccat
     2041 gaaaacgggc aagctcacgg ctcaagtgct gcaagcggcg ctgaaaaagt acctgcaaca
     2101 ccgggccaag ggcaaaaaca cgctgcacca cggccagcag agcctaaagc agcttaaaaa
     2161 gcatggggct gatctctcca acattgagat caccgaggcc aacattggag cgttcaagcc
     2221 atgcgccaag aaatacggcg tggattttac cttacgaaaa gataagacca cccagccgcc
     2281 ccactacgtt gtgattttca aggccaagga tgcagataac cttgatctgg cgtttcggga
     2341 gtttaccgcc aagacgcttt ccaaggagca gcggccctct atccgcaagg ttttgtccgc
     2401 tgtgaagcaa aaggcggcgg cccagaccaa gcagcgggcc aaggagaaaa tcaaggaaag
     2461 ggggctggaa ctgtgaagcc tgacgtaaag aaattgctga tcctgaacct cccgtatctg
     2521 atttttgtgt acctgtttgc gaaatgcggg gaggcgtacc ggctggccgc tggtgctgac
     2581 ctgtcgggga agctcctgca ttttgcggat ggttttgcgg cggcttttgc caacccgctg
     2641 ccaagcctgc acctgtttga cctgtgtatc ggtatcgccg gtgccgtgat cgtgcggctg
     2701 gtggtgtact gcaagagcaa gaacgtgaag aaataccgca aaggcatgga gtatggcagc
     2761 gcccgctggg ggacggccaa agacatagcg ccttacatcg accccaagtt tgaaaataat
     2821 atcctgctca cccaaacgga acggcttacc atgaccggca ggcccaaaga ccccaagaca
     2881 gcgcggaata aaaacgtgct ggtgatcggt ggcagcggtt cagggaaaac gagatttttc
     2941 gtgaaaccca acctgatgca atgctttccg accacggact atccgacttc gtttgtggtg
     3001 acagatccga aaggcacttt ggttctggaa accggcagga tgttccagca ggcgggctac
     3061 cgcattaaaa tcctgaatac cattaacttt tccaagtcca tgaagtacaa cccctttgtc
     3121 tacatccatt cggaaaagga cgtgctaaag ctggtaaata ccctgatttc caacaccaag
     3181 ggcgaggggg aaaagtcagc ggaggatttt tgggtgaagt cggaacggtt gttttattcg
     3241 gccctgatcg gctatatctg gtacgaggcc ccagcggagg aaatgaactt ctcaacgctg
     3301 ctggaaatga taaacgccag tgaagcccgc gaggacgacc cggagtttca aagccccgtc
     3361 gatctcatgt ttgagcgttt ggagcagaaa gaccccgacc attttgcggt gcgccagtac
     3421 aagaaattcc tgctgtccgc aggcaagacc cgttcttcca tcctgatttc atgcggtgcc
     3481 agacttgcgc cctttgacat ccgggaggta cgcgagctga tggaggacga cgaaatggag
     3541 ctggacacca tcggggacga aaagacggtg ctgtatctca ttatgagcga tacggacacg
     3601 acctttaatt tcattctggc tatgctccaa agccagctaa tcaacctgct ttgtgaccgg
     3661 gctgatgatg tgtacggcgg gcggctgcct gtccatgtac gcctgatttt ggatgaattt
     3721 gccaacattg gccaaatacc caatttcgat aaactcattg ccaccattcg aagccgtgaa
     3781 atatcggcct ctattatttt gcagagccag tcgcagctaa aagcgattta caaggacgcc
     3841 gccgagatca tttcggataa ctgcgatagt gtgcttttcc ttagtgggcg cggcaaaaat
     3901 gccaaggaga tttccgatgc gctggggaaa gaaacgattg acagtttcaa caccagcgag
     3961 aaccggggaa gccaaacgtc ccacggattg aactatcaaa aattaggaaa ggagttgatg
     4021 tcccaagacg aaattgccgt gatggacggc ggcaagtgta tcttgcagct acggggtgtg
     4081 cgcccgtttt tatcggagaa attcgatatt accaagcatc cccggtacaa ataccttgcc
     4141 gacgccgaca agaagaatac ctttgacgtg gacagatttt tgactatcac gcgccggaaa
     4201 cggcagcaag tggtaacgca ggatgaagta ttcgacctgt atgaaatcga cctgtcggac
     4261 gaggacgccg ccgctgaata aacagcggct tttttcattc caacaacaaa atcaaaaaat
     4321 cattatgagc cggaaaccgg cagaaagagg taaatttatg gcatttttta attccgcagt
     4381 tactactttg cagactatcg tgatcggact gggcggcgct ctgtgcgtat ggggcggcat
     4441 caatctgttg gagggatacg ggcaggacaa tccgggggca aaatcgcagg gtgtcaagca
     4501 gcttgtcgct ggcggcggcg tggccctgat cggtgtcact ctggttcccc tgctgtccgg
     4561 gctgctgggc tgatcctggc ctttgtccct gtccaaaccc ttaactaatc gcctccgcgt
     4621 cctcccggcc agaccgggag ggcgcgggaa aggaggtgct acccgtgatt agtgaaatca
     4681 ttgaagaatg gataaaaggc atcctcatgg acggtatcac gggcaacctg tccgggctgt
     4741 tcgatacggt aaatgccaaa gtcggagaaa tcgccgccga cgtgggacga accccgcagg
     4801 catggaacag cggtattttc aatatgctgc acagcctgtc ggaaaccgtg atcgtcccca
     4861 tagccggggc catactcgcc cttgtcatgt gctatgagct tatccagatg ataacggaaa
     4921 agaacaatat gcacgacttt gacagctcca tgttcttccg ctggatattc aaatccgcgt
     4981 ttgcaatcct gatcgtaacg aacacatgga acatcgtcat gggcgtattc gacgccaccc
     5041 aaagcgtcgt caatcaaagc gccggtgtga ttatcgggca gacatccatt gattttaaca
     5101 ccctgatacc agaccttgaa agccaattgg aggctatgag cgtgggcgct cttttggggc
     5161 tgtggttcca aacccttgtt gtgggcctca ccatgaatat cctttccatc tgcattttcc
     5221 ttgtgaccta tggccgcatg gtggaaatct atgttgtcac gtcgctgggg cctatccccc
     5281 ttgccacaat gggcaacgcg gaatggcgcg gcatgggcca agggtatctg aaatccctgc
     5341 tggcgctggg cttccaagcc tttttaatca tggttgtggt gggtatctac gcggtgctga
     5401 tacagaatat cggttccgct tccgacatat ccggcgcaat ctggggctgt atgggctata
     5461 cggtgctgct gtgcttctgc ctgttcaaga ccggcagtat atcaaaggcc gtattcgggg
     5521 cgcattgatc ccaaaatcca agcatacaca ggaggaactt gtttatttca acgtacaaca
     5581 tcatttacgc tgacccgccg tggcggtatg actgcaaaaa cgtacagggc gcagcggaaa
     5641 atcactattc caccatgagc attgacgagc tgtgcgccct gccggtggaa cggctggcgt
     5701 ccaaagactg cctgctgttt ttgtgggcca cattccccat gctgccggaa gctctgcggt
     5761 taatcaaagc gtggggcttt tcattcaaga ccgtggcttt tgtatggctg aaacagaacc
     5821 gtaaaagcct tacatggttt tacgggctgg gccgctggac aaggggaaac gcggaaatct
     5881 gcctgctggc aacacacggc aagccgaagc gtcgttctgc ctctgtccat cagtttatta
     5941 tcagcccgat tgaacaacac agcaaaaagc cggatgtgac ccgtgaaaaa atcgtagagc
     6001 tggcgggcga tttgccccgc gtggagctgt ttgccagaca gaaaaccccc ggctgggacg
     6061 tgtgggggaa cgaggtggaa tgtgacctta tcctgacgtg aaaggaggtg ccaaatggct
     6121 tatgtaaccg tccccaagga cttaacccat gtgaaaagca aggttgtgtt tgggcttacc
     6181 aaacggcaac tgatctgttt ttccggggcg ctggtgatcg gcgtcccctt atattttctc
     6241 acccgtgact atcttaccaa cagcgcggcg gccctgctca tggtatttgc catgctgccg
     6301 ggctttttgc ttgccatgta cgagcgtcac ggccagcccc ttgaagtggt gattatgcag
     6361 atcatccagt gctgcttcat ccagccaaag gagcgtccct atcagaccga caacacctac
     6421 accgcccttg tgcggcaata ccagatggaa caggaggtaa aggccattgt ccaaaaagga
     6481 aatcccaaga gaaaccgaaa aaacaaagct gacccgcgcc cagcgaaaag aaattgacgc
     6541 ggtaatccgt aaatataagg gcgacggcag gccccacacg gcgcagcaga gcatccccta
     6601 cgaggtcatg tacccggacg gcgtgtgccg ggtatcgccc ggcgtctttt ccaagtgcat
     6661 tgagtttgcg gacatcagct atcagcttgc ccagccggac acgcagacgg ctatctttga
     6721 aaaactgtgc gacctgtata actatgtgga cgcctccatt catatccagt tttctttcct
     6781 caatcggaaa gttgacccgg tgcagtacgc caagagcttt gagatcgcgc cgcaggggga
     6841 cgacttcgac gacatccggg ccgagtacac cggcattctg caaaagcagc ttgcaaacgg
     6901 caacaacggc atggtaaaga ccaaatacct gacattcacc atcgaggccg aaagcgtgaa
     6961 agcggcgcga gccagattga agcgcatcgg ctttgacctg ttaggctatt tcaagagcat
     7021 gggggccgta gcccatgtga tggacggctg ggaacggctg aacctgctgc atggcgtgta
     7081 ccacccggac ggcgagatat tcaattttga ctggaagtgg ctggccccgt ccggcctctc
     7141 caccaaggat tttattgccc cgtcctccct gtgcttcggc aatgcaaaga cattcggcat
     7201 gggcggcaaa tacggcgcgg taagtttcct gcaaatcctg tccccggagc tgtcggacga
     7261 tatgctggcc gacttcctca atacggaaag cggtgtttta gtcaatctcc atgtgcaggc
     7321 cattgaacag accaaggcga tcaagaccat caagcgcaaa attaccgacc ttgacgctat
     7381 gaagattgcg gagcagaaaa aggccgtccg cagcggttac gatatggaca ttcttcccag
     7441 cgaccttgcc acctacggcg aggacgccaa gaagctgctg acaaagttgc agacccgcaa
     7501 tgaacggctg ttccagttga cgttccttgt cctcaacgtg gccgacacca agcaaaagct
     7561 gaataacgac gtgttccaag ccgcaggcgt ggcccaaaag cataactgtc cccttgtccg
     7621 gctggactac cagcaggaac agggccttgc aagcagcctg ccgctgggcg tcaatcagat
     7681 caagatacag cgcagcctta cgacttccag cgtggccgtg ttcgtcccct ttgtgacgca
     7741 ggagcttttt cagggcggcg cggccatgta ttacggcatc aacgccaagt cccgcaacat
     7801 gattatgctg gacaggaagc aggcccgttg ccccaatgcc ttgaagctcg gcacccccgg
     7861 cagcggcaaa tccatgagct gtaaatccga gatcgtcagt gtgttcttaa cgacgcctga
     7921 cgatattttt atttcagacc cggaggccga atattacccc cttgtcaaac ggctccacgg
     7981 acaggtaatc cggctgtcgc ctaccagcaa ggactttgtg aacccgctgg acatcaacct
     8041 gaattattcg gaggacgata acccgctggc cctgaaatcc gactttgtgc tgtcgttctg
     8101 tgagcttgtc atgggcggca agaacgggct ggaagccatt gaaaagaccg tgatagaccg
     8161 ggctgtgcgc gtgatctacc ggccctatct ggcagacccc cgcccggaga atatgccgat
     8221 cctgtccgac ctccacaaag cgttgttaga tcagcatgtc ccggaggctg accgggtggc
     8281 gcaggccctt gacctgtatg tgtccggctc cctgaacgta tttaaccacc gtaccaacgt
     8341 ggacatcggc aaccggcttg tgtcctttga cattaaggag ctgggcaagc agctcaaaaa
     8401 gctggggatg ctcattgtcc aagaccagat atgggggcgc gtcacggcca accgaagcca
     8461 aggaaaggcc acatggtatt ttgccgacga gttccatttg cttttgaaag aggaacagac
     8521 ggcggcctat tctgcggaga tttggaagcg gtttaggaaa tggggcggca ttccaacagg
     8581 tgccacccag aacgtcaaag acctgctttc ctccccggaa attgaaaata tccttgaaaa
     8641 cagcgacttc attacgctgc tcaatcaggc gtccggggat agaaaaatcc ttgcggaacg
     8701 cttgaatttg tccaccgaac agcagaagta catcgacaat tccgaacccg gcgagggcct
     8761 tttgatcttt gaaaacgtgg tgctgccctt taccaacccc atcccgcaca acacccagct
     8821 ttacaagatt atgacgaccc gcttaaacga ggtggcggga gtatgacccg gcgacgccac
     8881 aaaggaggtg aaccaccatg aaagagctga aagccaaggc gaaagtgacg caggccatga
     8941 cccgcgacgg gctgacgctg gaaaatcagg ccaccggcga ggtggagaac atttccagcc
     9001 gggaggccga acaggatttg tccgcgccgg ggccgggcgg caccgccgat aagctgctgg
     9061 aacgggccga cgccatccat gacggccata aggccaagaa agccgcgaag caggccgggg
     9121 ctgtggccgc cgagggggac gctgccctgc accggccatc cgcccggctc caactgtcgg
     9181 aggaagaacg ggccgacccg gatttacagc cctatatccg aaaatcggac aaacgggccg
     9241 ataagctgga taaggcccgc gccgccatcc ccaagaagcg cgtcccggtc aaggaaaccg
     9301 tctttgacga ggcaagcggc aaagcaaaga ccgtcctgca ctttgacaaa caggacaagg
     9361 ggcctccctc cctgaaaccc aatccggcag gccgtcctgt ttccgaggtt tttctattcg
     9421 gccacgggaa aatccatgaa gtcgagcatg aaaacgtggg tgtggagggc ggccataagg
     9481 gggaggaact tgccgagcgg caggccggaa aagccatccg cagcaccatc cggcaccaca
     9541 ggctgaaacc ctactgggac gcggaaaagg ccgagcgcag gctattgtct gccaacgcgg
     9601 agtatttcta ccagaaatct ttgcgggata acccggagat cgcacaggcg gccagcaacc
     9661 ccatttcccg gttctggcag aaacagcaga tcaagcgcca gtacgccaag gccgcccgga
     9721 cagcgggcca gaccgcaggc gcggcggcac agggcgcggc caagacagcc ggggcctcca
     9781 cgaaagcggc caaggccgca gccaaagaaa gtgaacgggc ggcctccttt gtggcccgcc
     9841 actggaaagg ggcgctggcc gtccttgtgt tggggctttt gatgctgctt atcatcggcg
     9901 gcttacagtc ctgcaccgcc atgttcggca gcgccggaag cggcatcacg gcgtcctctt
     9961 acttttccga ggatagcgat atgttggccg ccgaggacgc ctacgcggag ctggaagccg
    10021 agctgcaaga ctatctggac aactacgagg ccacccatga ctatgacgaa taccattttg
    10081 accttgacga gatcagccat gacccctatg tgctgatttc cattctgtcg gcgctccatg
    10141 acgggatatt taccatcggg gaggtacagg gtgatttgtc catgctcttt gacaagcaat
    10201 atatcctgac agaaaacgtc gtggtagaaa cccgttaccg caccgaaacc gatacatgga
    10261 cggacgcgga gggcaacacc catacagaca cctaccaagt gccgtatgac tattacatct
    10321 gctacgtcac gctggaaaac ttcgacctgt cccatgtgcc agtctatatc atggacgagg
    10381 aaacgctaag tttctattcc ctgtatatgt ccacgctagg aaaccggcct gatctgtttt
    10441 ccggcagcca gtaccccaac gcctccaccc tgacgccgcc gacctactac gacgtacccc
    10501 cggaggcttt ggaggatgcc acctttgccg ccatgctcaa agaggcggaa aaatatatcg
    10561 gttatcccta tgtgtggggc ggcagctctc ccagcaccag ctttgattgc agcggcttca
    10621 tttcgtgggt aatcaatcat agtggatgga acgtgggacg gctgggggcg cagggcctat
    10681 ataacatctg cacccctgtt tccagttcgc aggccaagcc cggcgacctt gtatttttca
    10741 agggaaccta cgacaccccc ggcgtgtccc acgtcggcct gtatgtgggc aacaatgtga
    10801 tgctgcattg cgggaacccg atttcctaca cgaaccttac ttcaaactac tggcaatccc
    10861 atttttacag ttacgggcgt ttaccttaac gccagaaagg agctttcaat tatggcaacc
    10921 aaacttgacc gcatcgaaaa ggacatccag aaaaccaagt ctaagatcgc ggagtttcag
    10981 aaacagcttc gggagctgga aacgcagaaa accgaacagg agaatttgca gatcatccag
    11041 cttgtgcgcg gcatgaacat gaagccggag gaatttgccg cgttcttacg cagcggcgca
    11101 atgcaggccg cccctgccgc aaccccttac catgaacagg aggacaatgc ccatgaagaa
    11161 taagaccaga cggatttccc gtattctccc cgcacttctg gccgtgatgc tctgcgtcac
    11221 ggcctttccc gttaccgccc ttgcaggcgg caatgacccg gcaccggccc cgctgccgga
    11281 ggctacaacc gaacccgcta cgggcggttt ggagcctgaa acagacgaaa ccggcaccgc
    11341 cacggacggg acagaaaccg aggccgaaaa agataccggc cctctgaccg gcaaggacat
    11401 caccgacctg ttttccgcgc tgttcggttc caaggtgagc attgccgcca cggacgacgg
    11461 catccagatc accaccggca ccgacaaaaa agaacctgaa cagaccggca ccgtcaccac
    11521 caacggcggc aggctgaatg tccgcaccgg cgcggggctt gacaagaccg cgttcaccca
    11581 gcttcccaat gggacgacgg ttgaggtagt cggcacagac ggcgactgga ttaaaattct
    11641 cttgccggag cgcatcggct atgtccattc cgactatatg accgtcagcg aaaaggaagt
    11701 agcggctacc ggcgagggcg gtttttccct ctccattgac ccggaggaaa ttgcttctct
    11761 gctggaactg ttcaatggcg gcggggccag cgccgccctg tccccggacg ggaacctgtc
    11821 actgattgac gacatcggca gcgccgcgaa aaatggcaag cagtttatca ccgtggaaac
    11881 caaaaacggc aatgtgtttt atctgattat tgaccgggac gacgagggaa aagaaactgt
    11941 ccatttctta aatcaggtgg atgaagccga tctgctgacg ctgatggagg acggggaaac
    12001 cgtcaccccc gctgctgtct gctcctgtac cacgaaatgc aaggccgggg ctgtgaacac
    12061 gaattgcccg gtatgtaaaa ccaacctgac cgagtgcagc ggcccggagc cgcaggaacc
    12121 ccagccggag gaacccgaag ccccggagga agaacccaag ggcggcgcgg gcggcctgat
    12181 cgtgttcctg ctggtggcgc tggcgggcgg cggtgcggcc ctttactatt tcaagttcaa
    12241 aaagcccaag gctgaaacca ccggcagcga cgatttgggc gagtatgatt ttggggagga
    12301 cgaggatttg gaggacgagg aacccgaaac cgagtttgac ccggaagctg attttgtgag
    12361 tgaacaggag gacgaggaat gacatataaa cttgtaatcg cggaaaaacc cagcgtggcc
    12421 cgcagcattg cgggcgtgat cggggccacg gagaaacacg acggctattt ggaggggaac
    12481 ggctatctgg tgagctggtg catcggacat ctggtgtcct ttgccgacgc cggacgctat
    12541 gacgagcgtt tcaaaaaatg gcgctatgag gatttgccca ttctcccgga aacatggcag
    12601 tacatcgtcc ccgacgacaa gaaacagcag tttgacgttc tctgttcgct gatgcagcgc
    12661 cccgacgtga ccggccttgt gtgcgccacc gacgccgggc gcgaggggga attgattttc
    12721 cgtttcgtct accagatggc gggatgccaa aagccctttg agcgcctttg gatttcctct
    12781 atggaggaca gtgctattaa ggacggcttt gcccacctga aaccgggcgg cgactatgat
    12841 ccgctgtatc aatcggccct gtgccgggcc aaggccgact ggctgatcgg cattaacgcc
    12901 acccggcttt tttccgtcct gtaccacaag aacctgactg tgggccgcgt ccagacgccg
    12961 accttaaaaa tgctggtgga cagggacgcc aagattaccg atttcaagaa agagaaatat
    13021 cacatcgtcc atatcacggc gggcggcgcg gacgcggtaa gcagccgctt ttccgacgct
    13081 gccgaggcaa acaccgtcaa ggcggcttgt gcaaaagcgc aggccgtttg cgtttccgtg
    13141 acgcgggaga aaaagacgga acagccgccc aagctctatg accttaccac cttgcagcgg
    13201 gaggctaacc ggcttttcgg ctataccgcc aagcagaccc ttgactatgc ccaggcactg
    13261 tatctaaaga agctgctgac ctatccgaga acggatagtc aatatcttac cgacgatatg
    13321 ctgcccgccg tggaaagcct tgtgtccggc ctgtgggagc tggtgccgtt tgccaagggc
    13381 ctgaaccttt ccccgcagtt tgaccgcatc ctgaacagca aaaaggtgtc cgaccaccac
    13441 gccattatcc ccaccgctga atttgtgaag cagggctttg gcactctggc cgagagtgaa
    13501 aaaaagctgc tgtccctgat ctgctgcaag ctcttatgtg ccgtggccgg gccgcatatc
    13561 tatgaggccg tcaccgccac atttacctgt gccgggcagg agtttaccgc caagggcaag
    13621 accgtccttt cccccggctg gaaagagatt gaacgccggt tccgttcttc cttaaagacc
    13681 gacgccgacg aggacgccga ggcggtgcgg gagctgccgg agctttgcga gggccagacc
    13741 tttgcagacg tggccgcctc tgtcaccgag catttcacca cgccgcccaa gccctacacc
    13801 gaagatacgc ttttgtccgc tatggaacgg gccggggccg aggatatgcc ggaggatgcc
    13861 gagcgcaagg gattaggcac accggccacc cgcgccgcca ttctggaaaa gctggtgcag
    13921 atgggctttg tccagagaaa aggcaagcag ctcattccca ccaaggacgg catcaatctg
    13981 gctgtggtgc tgccggaggc gcttacttct ccccagctta ctgccgaatg ggaaaaccgg
    14041 ctgaccgaga tcgccaaggg gcaggccgat cctgacgaat ttatggacgg catcgagacg
    14101 caggcgcggg agctggtgca gacctattcc tgtatcagtg aggaaaagca gaaattgttt
    14161 caggccgagc gtgttcctat cgggacgtgt ccccgctgtg gtgaggctgt ctatgagggc
    14221 aagaaaaact actactgcgg aaaccgggcc tgccagttcg tcatgtggaa gaatgaccga
    14281 ttttttgagg aacgcaagaa agcgttcacc ccgaagatcg ccgctgcgct gctcaaaacc
    14341 ggcaaagtca aggtaaaggg cctctattcc gtaaagaccg gcaaaaccta cgacgggacg
    14401 gtgcttttgg ctgataccgg gggcaagtac gtcaactacc gcattgaaca caggagctaa
    14461 aggacagtaa cacagcaagc atagggagtg tggctacact cccggtaaaa tcccccggcc
    14521 gcgtccctgc cgggccgggg atttttgctt gttggggaag tccccaaccc cctatttttt
    14581 gaaacagaac agagaaagga gtgaccgcgt gaacgaagta ttttctatcc aagtccataa
    14641 ccggcagttt ttggaacagg gcaaacaagg cgtctggctg gatttgccca ccacaaccga
    14701 aacgctgcaa gccgccctgc gggatgttgg cattactgcc gacaatccgc aggatttttt
    14761 tatcaacggg tattcctgcc cggaggacag acaccttgcc attccctatg acatggtgct
    14821 ggccgccgac gtggacgagc tgaatttcct tgccgcccgg ctgggccagc ttgacgccgc
    14881 cgagatcgca gagctgaacg ccgccctgca aaatccccgt ggcggctttg agaatatcgg
    14941 ccagatcatc gactacaccg aaaatgtgga ttactatgtg catcttcccg acgttagggg
    15001 ggatggacag ttgggcgact actacctgaa ccgttccggc atggtggata tgccggagga
    15061 atggaaagcc gggattgata cggcgcagtt tggacgccac attgcccagc aggaacaagg
    15121 cgtttttacc cagtacggct atctggtgag aagcggcgac gaatggcagc gcgtccatga
    15181 gggccagccg gtgccggagg aataccgggt gatgcactac ccccagccgg aagctgaccg
    15241 ggaggaaccg caggcccagc agccggaggc atccgaaagc cccgacaaag cgccgccccc
    15301 ggttatcccg atcatgctgg acggcatgaa cagcaaagaa cgcatgaaag tgattactga
    15361 ccgtctggaa accggcgtac aggagctttt tgaaagtagc cgctatatgg cttacttatc
    15421 cgctatgtcc aagatgcacg attacagtct gaacaatacg ctgctgatcg ccatgcaggg
    15481 cggttcgatt gtggcgggct ataacaggtg gcaggatgaa tttgaccgcc atgtgaagcg
    15541 gggcgagaaa ggcattaaga tactggcccc ggccccgttc aaggttaagc agcagatgga
    15601 gaaaaccgac ccggccaccc agcagcccgt gatcggcgcg gacggcaagc ccgtgaccga
    15661 agaacaggaa gtgacggttc cggcctttaa ggtggtgaca gtctttgaca tcagccagac
    15721 cgagggcaag gattttccca tgccctatat cagtgaactt accggcgacg tgcagcagta
    15781 tcaggatttc tttgccgcgc tggaacggac atcaccctat cccataagca ttgagccgat
    15841 ttcagacggg gccaagggcc gctgcttcta cgcaaaacag cgcattgcca tcaacgaggg
    15901 catgagcgaa ttgcagaccc taaagaccgc catccatgag attgcccatg ccaagctcca
    15961 cgccattgac cgggaggccc ccgccgagga acaggcggcc cggccagacc gcagcacccg
    16021 cgaggtacag gccgaaagcg tggcctatac cgtctgccag tattacgggc tggacacgtc
    16081 ggactattct tttggctatg tggccgattg gagcagcggc agggagttat ccgagctgaa
    16141 agcctccctt gaaaccatcc gggccacggc cagcgaattg ataaccgaga tcgacggcca
    16201 ttttgcccag cttcagcagg agcgcgaggc ccggcaggaa caggaggccg tcacggttga
    16261 cgttaccccg gaggcagcgg ccccggcgca ggccgaggaa gaacaggccc cggcccttga
    16321 tccggcagcc gagccgcttg tgactgtgct atggagcgaa agcccccagc taaaggacgg
    16381 ccagcaaatg ccgttgcatg aggccgacgc gctgtttgcc cgtctggatg cagcatatcc
    16441 ggcagaggca ggctatgaca aaaccgcgtt ccgcattgac tgtatctttc agggcgagcc
    16501 ggacagctac gaggggcggc aggattttgg agatagggac ggttccctga tcgaacatat
    16561 ccagagctac caccaatttt acgcgcagga cgaaaactgg aaaaagcatg taatcgctac
    16621 aaccggcata gagggctggg agcaggacaa ggcccatcgg gatatgctgt taggcgagtt
    16681 tgtcccctat atgaagctgc attgcagcct tgcccaaatg gaacagacgg cgcagggccg
    16741 cttacagtcc ggggaaaccc tgacgccgga ggaaacggcc tatttggggg cgcttctctc
    16801 ttatgtgcag gagtgccgcc ccatgctcaa tcagggccag tatcagttgc cggagccgcc
    16861 gaaactggct gacttcgacc agagcttgca ggactacaaa gcacaggtac aggccgagat
    16921 cgcgcaggag gccgccgcag ccggtatgac cgtggaggaa tacgcggcgg ctggctatga
    16981 agcaccccaa caggacacct tttccatcta ccagcttcga ggcggggagg aaacccgcga
    17041 ctatcggttt gagccatacg agcgtttaca ggccgcaggg ctggccgtgg acagtgccaa
    17101 ctatgacctt gtttatacgg caccgctgga taaaagcacg tctttggagg atatttaccg
    17161 cacattcaac atcgaccacc cggcagattt taggggacac agcctttccg tttccgacgt
    17221 ggtggtgctg caccagaatg gacaggacac cgcccactat gtagacagct tcggctatat
    17281 ggaagtgccg gagtttttgc gggaaaatcc cctgcgtacc gccgaactgt ctacggagca
    17341 gaacgaaaac atgattgacg gcattatcaa caatacgccg cccgaaccgc agccggagga
    17401 acccgaacag ctatcttttg aggatgtggc agttgcttcc ggccagacac aggaggaacc
    17461 cccggaggct gcgcccccgc aaacggctgt ccgctattat cccatcaatg agggagccgc
    17521 ccgccgcgcc aaggaagcca tgagcttttc tgactaccgg cccggcagcg ccacggcgga
    17581 ataccggcac tatgtcgatc aggccgtgga aattgcggag cgccagaaaa agcgtgtgga
    17641 gccagagtat cacgaaaaga tagacagcct ccttgacacc tacgcccgca agctggccga
    17701 gaacatgaat aagggctatg agattaccgc ccgcgtcccc tctgtcctga ttgccgggcc
    17761 gtccaatttc ccggtacggg cgaaagaaaa gcagaacgcc gccagtgacc gcaacatgga
    17821 ggaatttcag tacattcagg gcttgcttga caaaatccgc agcaccggca tgggtggtat
    17881 cagcgccgac gatccgcagg ccgtttccaa gctggaaaag aaactggaaa agctggaagc
    17941 gtcgcaggag ttgatgaagg ccgtcaatgc ctactaccgc aagcatggga cgctggacgg
    18001 atgcccccat ctgatcgaaa gaggcattga aaacctgaaa gcggatatgg cgtcgggctg
    18061 gcactatgag aaaaaaccgt tccagtcctg gcagctctcc aacaataacg ccgagatacg
    18121 ccggttaaag ggccgcattg aggaattgac ccgccaaaag gaggcggcct atgtgggatg
    18181 ggagtttgac ggcggcactg tggagatcaa ccgggtggcc aaccgcctgc aaatcttctt
    18241 tgaggggaag ccggatgctg ctgtacgcga cgagctgaaa agcaacggtt tccgctggtc
    18301 gcccaaggcc ggggcatggc agcggcagtt aaacgacacc acaatccgcg tcgctgaccg
    18361 tatcaagtgc atccagcccc tttccggcga aaagcccagc gccttacagc ttgcggcccg
    18421 cagggagaaa gaaaagccct ctatccgggc gcagctcaac gcggccaaga ccgaacaggc
    18481 caagcagcca ccggcgcggg aaaaatcaaa gggattggag gtagagtaaa tgcagaagtt
    18541 tgaaaatgtg gacgttctgg ccgcgctgga acagatcatg cggcagaaca ccgcgtttta
    18601 tcaaagtgac tttggcattg acaaagacat tatcaggcgg gatgccgcca gcgatcaggc
    18661 cgcagacaag accctgctct ggatgtcccg gccctccggg acgtactgtt tccgggaacg
    18721 tgatgttttc ctgaaagaca cccgacagta caacacatgg aaattttacg gggagcagac
    18781 ccgtgacaag atactggcct acgcggtgga gctgaccggc acacagggcg gcactatccg
    18841 gggcaatctc tatgagctgg actatccgca gcatttccgg cacgtcattg aaaccgccca
    18901 gccggtgagt gtgaaccggc tcttttatga gcatggcacc cgtgacatcc cggagagcca
    18961 gcgttttgac ggaagccctg accgggtatt gggaaacttt ttgtactatg aggcccagcc
    19021 ccatgacccg gctgtgctgc aggaggcgct acggacggag cagcacagcc gggggcgggc
    19081 cgtccccggc gatttcaaag tccacgtcac cgctttgcat gacagccgga ttgaaaccga
    19141 ggcccggcgt attgtggaca gcctgaaaga tctgtccgcg cctaacagcc ccaataaaac
    19201 gcatttcatg gtggagatct ccccgcactt tgcggcgatt gcttccacca aggataatga
    19261 ccggctcttt gccatgctgc cctataaatc cctgtgtttt accgggatga aaggcaggca
    19321 tggcgtgtat gccgtgatta accgggacga gcgccgggat gtgagtattc gcaggccccg
    19381 gccctctatc cgcaagcagc tatccgacag caaacaggcc gccagcccaa aaaaggcggc
    19441 ggccagaacc aaaaagaatg aattggaggt ataaggaatg atgcacttta ccgtggagga
    19501 agaaaacctg atctgtatgt accacaatgc agaccggcgc agaacgataa acaggctcac
    19561 cgccgtcatg ccggttatgg atggggatat gcgggcgcag gcccagcaga ccctttccaa
    19621 gctggaacgc atgacggatg ccgactatga cggccagaag ttccacttca cagacgaata
    19681 acgaacagca gacgccgggc gcggcggcca tgtggtcgct tgcgtccggc gtcttttctt
    19741 tttgcctatt cctacgcatt tagaacccgg tattgtcggg gataggatga agtattcgct
    19801 tgcccctgca aacatgcggg agaagccttg cagcgggcgg ttttcaatcc cttaaatgcg
    19861 taggttgcag ctataattag acccctgaaa cagatatagc cgcgcagcgg gtgtatctgt
    19921 ttcaggggtg tgcaggtgat agccgcaaag cggcgtaaga gggtgcagcc ctcttgccgt
    19981 ctatctctgt tccagcggga agctcggcaa tgcttccagc agtttcaggg aaatgcgctg
    20041 ccgtatatct tcgtcaatga ctttcttctt tttgccgttt gcctgtctga tctccaccgt
    20101 ggaaagctcg ttgatgtagt cagcataatg ggccaacact ttttccgtgg cccacctctc
    20161 accggcaacg gcggctttga tcgtttcata gtccagcagc ttttcttgtc cgtccatcct
    20221 gatacccccg tcagactgat tttttctatg ataccatatt cggaagcatg gaaccagaga
    20281 aaacggcgct tttctgctgg taaattctac gcatttagaa cagcacttcg gcggggatag
    20341 gataaaacac ccacataccc cgctgaccat gccggaaaag ccttgaaata taagggcttt
    20401 tacagctcta agtgcgtagg tttccagtat cttttccgct ggcgctcggc ctctttgcgg
    20461 cggcgcatcc gtttggagca ggccgcgcag tatttggccc ggttagactt cggcgtgaac
    20521 gtggccccgc actcacagca gcgtttcact tcgtcccggt ctttggtgat ctcggcatac
    20581 agggccgcat ccagcgggag gacagcggcc ttaaaccagc ggcacagaag cgaataggaa
    20641 atgctctgta cgcaaataca ttcttcgccg tcgtccagca acaggcagtt gccgtcacaa
    20701 tagttgcagc actcatgcgt cagcttccgg gccttgcgat attgagggta attcattcgt
    20761 ggaatactca tagctcttgc gtccattcct ttcccggcgt catacgcaaa atgccgtcca
    20821 cattctgctt gatgatgccg tattcctgca tctgcttttt cgcttcgccg tacttctcat
    20881 acagccgttc cttttcctcg gccaatcgct tgtactcggc tttcagggcg tacagatcgg
    20941 ggagcttttt cacaccctgt ccctttaggg cctttgccgc agcttcatac aaaatcaacg
    21001 tgctttcatg ctcacgccgg aattttgcct tatccgctgc attgcggtat tccatagcca
    21061 cgggccagag ctgcttgtag gtagaaatat tctttatcag caccgccata tccgcaagcc
    21121 ggtgttccat agctttgagg gtagcggcgg cctcgtcgct ggcggcggtg atctcggcca
    21181 ctttgctttc caaatccggg taggtgtcta tcccatgttc agtcaggaaa ttcaaagtct
    21241 ttgcggcctg cttcaaattg tggagcttcg cccacctctc atagcctgcc gactgctggg
    21301 ccttaatgtt gttttccaga tcaatccgca aagaaatccc cttgcgctct ttgggcgctc
    21361 tggtgataac gcggcctttg atacgctctt tgatggcttc ctcggtgtag gcttccccca
    21421 atgtcttgca gcgggtaaag cgttcctgtc cgggagcgcg gaaagaaata aactttcccg
    21481 gcttgatctc atagccctgc gcctgcatga gccgcaggaa atcatcaaaa tcttttgcct
    21541 gcgggatagc ggcgtcaatg gctgctttga gcttcgcttt ccagctcgtc cctttccgct
    21601 gggcgtccca ctcggcatag ctcttgccct tactctggcc gggcttcacc acggacaatc
    21661 cgttttcctt gcacagcctg tcgctggtgc gccggatata ggcatagctc tgtttgttgg
    21721 aaatgtactt gcgctgattt accatatcca cggcacagaa aataatgtga ttgtggacgt
    21781 ggcccttatc aatatgggta gtcagcacat agggatattt cccttgcagc acttcctcgg
    21841 caagctgctt cccgatctca tgggcctgtt ccggcgtggc ttcgccgggg gcaaaggatt
    21901 gtatcaggtg gtggcccaga ttattgccct tttggtatgc ctgcgccagc agcatttcaa
    21961 attcaatgtc cgctgtttca taagagcagg caaaggaggc caccagcagc ttgccgtcag
    22021 ttttgtccgg gttctcgatg tagtcaaggg cttttttcag cgttgacttg ataggatgta
    22081 tctttgtaac tgccatatct gcgccagcgc cccctttata tcctcgatgt cctgtgcgta
    22141 caccggcccc ataccgttca gcctctttgc aatctgattg acgttgacgc cgatcttctg
    22201 tatctcggcg gtctgcgccc ggatgtcgct ggtgtccatg ttgacgatat agccgtcaat
    22261 gagcatcttc cgggcgtagg ctgaaaagtt cttcgtatgc agcagcgcca ttttctgttc
    22321 aatcatagcc cgttcctccg gcgtcacagg gacgcgcagc acgatttttc gctttctgtt
    22381 tgccatgctt caccgtcctt tccattcagg ggtttgggga tttccccaac aagcaaaacg
    22441 gacgcggccc ggcagggacg gggcaggccg tttttccggg agtggctaca ctccctatgc
    22501 ttgctacgtt actgtttctc cactaacaag acgtttccaa agccccaaac tacccgcaaa
    22561 atagccctct ggaaagaaaa aagtgcaaaa aaatagaagc tacgctgtgc agctcccgct
    22621 aaaagtaaaa cagaggatgc cagttacaca tcctccgttt cattcttctt cggcttttca
    22681 attagtatgg cgctgtcaat cgcgccctcg atgatcggca ggtattcttc ggggcagagt
    22741 ttcagcttgt ggctgaccct ttgccgcagt tcgctttcct cccgcatgat ctccgggtta
    22801 aagtagcgtt ccacaggaag cccgcaggct ttaataagct gtatgacaac cggcagactg
    22861 ggaatggccc gtcgttttcg atgttggcaa gatagcgcca gtcaatattt attttctctg
    22921 ccattgcttt gcgcgaaacg cgctttgctt gccgggccgc tttcacatcc gcgccgaaag
    22981 tttcaaagcc gggacaatct tcaatattcg ccatatcgca cctcccactt acattgtata
    23041 tttcatactc tgcccgtgga atgttggtat atgcaccttt cttaaagttt atatttcaca
    23101 ttttgtttct tttattcttc gagcaaaaga attataatgt accctgtgga ggtgtactat
    23161 ggactacatg acgttgaaag aggcaggcga gaaatggggt gtgcccccac gatggataaa
    23221 ctactattgt gctgcgggac gcatccccgg cgctgtaaag atggcgacga tctggctcat
    23281 tcccaaaact gcggaaaagc cgattgacag gcgtacaaag aaaggaaagg cggttactga
    23341 atagtataat gaaaccggcg cattttggat atggttttga agagagagaa agcatggtat
    23401 tttgtcacgg aaaaactata agatgataga tggcaggctg ctccagaccg ataaaaagta
    23461 ttctcatctg aaacagaaag aaaagattta cacatggatg tatgaagaag cgaaacttta
    23521 tcatgacaga aatggaaaat gcccgaaaca aagacgagga agctgctgct gtatcagccg
    23581 tatatggtag aattgaaaag gccggcatct ggattcttta tggtgaagtc tccagacatt
    23641 ggataactgc tggtctaatg cgcctttgag tatggggtga ttgattttaa taccggggag
    23701 gtacggcttt ttgaggaaaa tattctggga tttacatttg gcgattatta catttcctgt
    23761 aactgcaagg acacggatga tgaagatatg aggaatatag acttgctgat tttctactgt
    23821 cttgaacggt attaggactg aatctgctgc gcggagtgcg gcaagagcga ccggagggag
    23881 tacacacagg ccctgcctgt gtgaaaagcc ataccgcaag gtgcattcgc aaaaaagagg
    23941 ccgcgcattt tgctgaggct tggggtgtcc ccaacaagca aaacgagaac gccgcaggcg
    24001 ggcaagtggt ggatcagaat atccgtaaag gatattctga tccattgctt gccagtatta
    24061 tcgggatgtt ttgacaaccg ctgtaatcga aacatcccaa acattaagaa ggtgttaatt
    24121 attattatct tgatttaatt cgtttaaacc aataatatag atacatacac catgaaaaga
    24181 agcgagtatc ccaatgacgg atgattaaaa tccgaaaaga aatcgctttg aaactacagg
    24241 gaaactacag actgttatgt tatcttctta aaatggaggg atttttatgt cgatacgaat
    24301 tctacttgtc gaggatgatg atcatatctg taatacagta agggcgtttc tggctgaggc
    24361 aggatatcag gtggatgcct gcacagatgg aaatgaggca tacaccaagt tttacgaaaa
    24421 cacttatcaa ctggttattc ttgatattat gctgcccggt atgaacgggc atgaactttt
    24481 gcgtgaattt cgtgcgaaaa atgatactcc cattctgatg atgacagccc tgtcggatga
    24541 cgaaaaccaa atccgggcgt ttgatgcaga ggcagacgac tatgtaacaa agccattcaa
    24601 gatgcagatt ttactaaagc gggtggaagc cctgctgcgg cgcagcggtg cgctggcaaa
    24661 ggaaatccgt gtcggcaggc tgacacttct gccggaggat ttcacggtac tttgtgacgg
    24721 tacagagctg cccctgacac gaaaagaatt tgaaatcctt ttgctgctgg tgcagaacaa
    24781 aggcagaacc ttaacgcatg aaatcatttt gtcacgtata tggggatatg actttgaggg
    24841 tgatggcagc acagtccaca ctcatatcaa aaatttgcgg gccaagctgc cggaaaatat
    24901 catcaaaacc attcgcggtg taggataccg attggaggaa tcataataat ggaaagaaaa
    24961 gggattttca ttaaggtttt ttcctatacg atcattgtcc tgctactgct tgtcggtgta
    25021 acagcaacac tgtttgcaca gcaatttgtg tcttatttca gagtgatgga attacagcaa
    25081 acagtaaaat cctatcagcc attggtggaa ctgattcaga atagcgatag gcttgatatt
    25141 caagaggtgg cagggctgtt tcactacaat aaccaatcct ttgagtttta tattgaagat
    25201 aaagagggaa gcgtactcta tgccacacca aatgccaata catcaaatag ttttagaccc
    25261 aactttcttt atgtggtaca tagagatgat aatatttcga ttgttgctca aagcaaggca
    25321 ggtgtgggat tgctttatca agggctgaca attcggggaa ttgttatgat tgcgataatg
    25381 gttgtattca gccttttatg cgcgtatatc tttgcgcggc aaatgacaac gccgatcaaa
    25441 gccttagcgg acagtgcgaa taaaatggca aacctgaaag atgtaccgcc gccgctggag
    25501 cgaaaggatg agcttggcgc actggctcat gatatgcatt ccatgtatgt caggctgaaa
    25561 gaaaccatcg caaggctgga ggatgaaatc gcaagggaac atgagttgga ggaaacacag
    25621 cgatatttct ttgcggcagc ttctcatgag ctaaaaacgc ccatcgcggc tacaagcgtt
    25681 ctgttggagg gaatgcttga aaatatcggt gactacaaag atcattctaa gtatctgcgc
    25741 gaatgcatca aaatgatgga taggcagggc aaaatcattt ccgaaatact ggagcttgtc
    25801 agcctgaatg atgggagaat cgtacccata gctgaaccgt tggacatagg gcgcacggtt
    25861 gccgagttgc tgcccgattt tcaaaccttg gcagaggcaa acaaccagcg gttcgtcaca
    25921 gatattccag ccgggcaaat tgtcctgtcc gatccgaggc tgctccaaaa ggcactatcc
    25981 aatgtcatat tgaatgcagt tcagaacacg ccgcagggag gcgaggtacg gatatggagt
    26041 gagcctggtg ctgaaaaatg ccgccttttt gttttgaaca tgggcgttca cattgatgat
    26101 actgcgcttc caaggctgtt caccccattc tatcgcattg atcaggcgcg aagcagaaaa
    26161 agtgggcgaa gcagaaaaag tgggcgaagc ggtttaggac ttgccatcgt acaaaaaacg
    26221 ctggatgcca tgagcctcca gtatgcgctg gaaaacacct cggatggcgt tttgttctgg
    26281 ctggatttac cgctcacatc aacattgtaa atatttaaaa cttaaatgat tttgggctct
    26341 ttgtcaaata ggactgatag agtgagataa gaacatctaa ggtagaattc cttttctact
    26401 ttagatgttt tttgattcat aggtaatcag attatttagt aagaaaattc tggtcttcat
    26461 tttccgaaag cttcgaaagc cataagcgac tcgtttcaat gctttgatgt gggtatgcag
    26521 attttctatt ttggcatttg aataaggcaa ttcgagggct aaacgaatgc cggattcata
    26581 gtttataaaa gcttttttta tagaatgcag ttcttttgga acggaattgg gcatcgttct
    26641 tacaagttta aagaaagtgt ccgcctcttt gtcgtgaaac gcttgaagaa tttcttgata
    26701 gtaaaaatag gcgattcgta attcgtcaga gatcgaaagc agacgatcca ccacttcact
    26761 ttcggtgaga tacgcccaac caaaattgcg ccatttggtc catttgtcat aaacaagctt
    26821 gtcctgtcgt ttgatcagaa gccgagacaa cgcctttaat tgtcgataat atttggcttg
    26881 tgttggatcg tttcgatcaa agcttttcat gattcgtacg cgaatatcct caaatttacg
    26941 aatgagatgt ttgacaatgt gaaaacgatc cacaacgagt tttgcctttg gaaaacattc
    27001 ctttatcaga gaggcataag aaacattcat gtccgtcacg atgaccttta ccttcaatcg
    27061 tgcgcgtcgt tcaaattgca taaaataaga aacgagagcc tttttcttcc gtgaaggaag
    27121 aatatccagt aattttccag tatcgccatc catacaagaa aaggagtagg gaccgacttg
    27181 atttttcagt gaacgaaatt catccattaa taaacaacgc ggtaaccaat ttctttttac
    27241 ttttgtcatg gggatcagag aagcgagtgt ccgagaaacg gtcgaccaag aaacgccgca
    27301 atgcttagca attgtcgtca ttgcttgttt ttcagttagc tcttctaaaa ttttatagcg
    27361 cacttgttta gcgataaagc agtttctatc gacaatgtag gtattcgccg taaaataggt
    27421 gtggcagcca cgacagtggt agcgttgttt cgctaaagca agataagtca gttggttcgc
    27481 acatttatta agttgaatga gcgatttttt ctttccgttc ttaacgatca tgccttcatg
    27541 attcatctgt ttacacaaag gacagcgacg aatttcttta cttaacgtcg cagaaacaac
    27601 aagactcttg atattcttaa tgctcttcga ttccacattt gtgatgaaaa tgtttttatc
    27661 tttgattcca agtagtagtt tgatatgatg aagatcaggc atacagaacg ctcctttgat
    27721 tgtgttgtgg tgattcaatt ctaacggagc ttctgtatgt tttgtttttt catgctcaaa
    27781 agggaccgat agaatgattt tctatc
//
LOCUS       DADVXV010000033        27424 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.033, whole genome shotgun sequence.
ACCESSION   DADVXV010000033 DADVXV010000000
VERSION     DADVXV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.033"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            245..1414
                     /locus_tag="KB969_001323"
     CDS             245..1414
                     /locus_tag="KB969_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBB6869320.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            1887..2441
                     /locus_tag="KB969_001324"
     CDS             1887..2441
                     /locus_tag="KB969_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6869321.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(2614..3087)
                     /locus_tag="KB969_001325"
     CDS             complement(2614..3087)
                     /locus_tag="KB969_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6869322.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            3099..3635
                     /locus_tag="KB969_001326"
     CDS             3099..3635
                     /locus_tag="KB969_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6869323.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            3675..4046
                     /locus_tag="KB969_001327"
     CDS             3675..4046
                     /locus_tag="KB969_001327"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6869324.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            4330..5601
                     /locus_tag="KB969_001328"
     CDS             4330..5601
                     /locus_tag="KB969_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBB6869325.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            5846..6871
                     /locus_tag="KB969_001329"
     CDS             5846..6871
                     /locus_tag="KB969_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6869326.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            7165..8274
                     /locus_tag="KB969_001330"
     CDS             7165..8274
                     /locus_tag="KB969_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6869327.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            8357..9253
                     /locus_tag="KB969_001331"
                     /pseudo
     CDS             8357..9253
                     /locus_tag="KB969_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            9269..10093
                     /locus_tag="KB969_001332"
     CDS             9269..10093
                     /locus_tag="KB969_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6869328.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            10125..11435
                     /locus_tag="KB969_001333"
     CDS             10125..11435
                     /locus_tag="KB969_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HBB6869329.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            11583..12842
                     /locus_tag="KB969_001334"
     CDS             11583..12842
                     /locus_tag="KB969_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6869330.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            12852..13724
                     /locus_tag="KB969_001335"
     CDS             12852..13724
                     /locus_tag="KB969_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6869331.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            13736..14566
                     /locus_tag="KB969_001336"
     CDS             13736..14566
                     /locus_tag="KB969_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6869332.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            14606..16789
                     /locus_tag="KB969_001337"
     CDS             14606..16789
                     /locus_tag="KB969_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6869333.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            16850..18070
                     /locus_tag="KB969_001338"
     CDS             16850..18070
                     /locus_tag="KB969_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HBB6869334.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            18067..19527
                     /gene="gtfA"
                     /locus_tag="KB969_001339"
     CDS             18067..19527
                     /gene="gtfA"
                     /locus_tag="KB969_001339"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HBB6869335.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            19604..20710
                     /locus_tag="KB969_001340"
                     /pseudo
     CDS             19604..20710
                     /locus_tag="KB969_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            21032..21241
                     /locus_tag="KB969_001341"
     CDS             21032..21241
                     /locus_tag="KB969_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6869336.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMASKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            21234..21383
                     /locus_tag="KB969_001342"
     CDS             21234..21383
                     /locus_tag="KB969_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBB6869337.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            21537..22202
                     /locus_tag="KB969_001343"
     CDS             21537..22202
                     /locus_tag="KB969_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6869338.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(22486..23571)
                     /gene="xerS"
                     /locus_tag="KB969_001344"
     CDS             complement(22486..23571)
                     /gene="xerS"
                     /locus_tag="KB969_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBB6869339.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            23905..24138
                     /locus_tag="KB969_001345"
     CDS             23905..24138
                     /locus_tag="KB969_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBB6869340.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            24135..24542
                     /locus_tag="KB969_001346"
     CDS             24135..24542
                     /locus_tag="KB969_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6869341.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(25679..26197)
                     /locus_tag="KB969_001347"
     CDS             complement(25679..26197)
                     /locus_tag="KB969_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBB6869342.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            27315..>27424
                     /locus_tag="KB969_001348"
     CDS             27315..>27424
                     /locus_tag="KB969_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6869343.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT         9390 a         4170 c         5065 g         8799 t
ORIGIN      
        1 ttattctttt attactatgt ttgggtttta tagcaaagaa agtttaataa gagtttggac
       61 ctagcaaaca atattaatga ggtcattaaa tcttattatc tttagtgata taacgaaata
      121 tctacacaga caaaatgata gcgtaaaata ttttgtgtaa atagatattt agggtagaaa
      181 aaaagaaagt ccattctgta aaattaaagt taccacaacc gaaattttat aggaggactt
      241 tctcatgccc aattttacta cagaaattat ggaaacacta atcaataaag gtgatttaga
      301 tgaattattt cgatgtcatt tagaattagc tgttaattca ttattgcagg ctgaattaac
      361 agcttttctt gattatgaaa aatatgatcg tgctgggttc aattcaggta attcccgtaa
      421 tgggaattat tcacgttcat tcagaacaga gtatggagaa ttaaatttgg taattcctag
      481 agatagaaat ggtaagtttt ctcaacaaac tttacctgct tataaaagaa ccaatgactc
      541 tttagaaacc actattattc agctatttca aaaaggaatt actatgtctg aaatctctga
      601 attgattgaa aaaatgtacg ggcatcacta tacgccacaa accatttcaa atatgactaa
      661 aatagtttct gaagatatta ttgcctttaa agaaaggtcc ttagaatcca gatactctgt
      721 catttttatg gatgctactc acattccttt aaaaagacaa actgtttcaa aagaagcagt
      781 ttatattgta attggcattc gattagatgg aaccaaagag gttcttgggt ttagtcttgc
      841 tccaactgaa tctgcttatg tttggaaaga gattcttcaa gacctaaaag accgtggttt
      901 aaaagaggtt ttattagtcg taactgatgg tttaagtggc attaacgata gtattcatag
      961 tgtttatcca aatgctcaat ttcaacaatg ttgtgtccat atatctagaa atatcgctca
     1021 taaggttcgt gttagtgatc gacaagaaat ctgtagcgat ttcaaattag tttatcaagc
     1081 aagttcaaaa gaagaagcaa ataatcaaat aaggtttatg atagataaat ggaaaaagca
     1141 gtatccacga gtggttaaat tgctcatgaa tcctgctata ttaacctttt ataatttccc
     1201 tccgtcaatc agaagaacta tttattcaac taatttgatt gaaggtttta acaaacaatt
     1261 aaagaaatat accaaaagaa aagagcaatt tcctaatgaa gaatctctgg agagatttct
     1321 agtatctcaa ttcaacaact ataatcaaaa gtttctatgc cgagttcata aaggttttaa
     1381 agaaatacat gatacattag aatcaatgtt ttaacttgat caacagaatg ggcttttcca
     1441 tttacacaaa attattgacg ctcccgacaa aattatgatc ttgcgtaaag ttataaaata
     1501 ttaataaaaa tattttatta atgaaaagct tggtagcacg gttattcata tgctaattta
     1561 tttcacttta tagtaagggg agttcttagt atattgttca aacttaaatt tcatataatt
     1621 taattatgta aattagctat tctaagaact tctacggata actgcccgtc taaaatttaa
     1681 ataagagctt agaatcttca tataagtaag gttaattttt ttgtacaaaa aagtcggaat
     1741 attctgagtt actgaaatga tataaaatca taaactaaat cccttgattt tattgacttt
     1801 caaaagttta tatatataag ttaatgatta tggtaaaata tatacataat cattaactca
     1861 gaatattttt aagaagggaa acaatagtga gctataatgt acaaccgtta aggacaaatg
     1921 aagagataca agattttcag ttttggctaa gaagaacaag taatccggaa agagatagtt
     1981 ttttattttt gtttggaatc aataatgggt tacgtatgtc agatattata ggattaaaag
     2041 ttggagatat acgaggcaaa agtaagccta ttattgttga acataaaaca ggtaagcgaa
     2101 aaccgatttt tatagataat ttgagagaag aaattttatt atatactgaa ggtaaagaag
     2161 aaaatgattg gttatttccg agtcggcaac aaggtcgaca tataacaagg gatcgtgtct
     2221 atcagatata tgcagatata gcagaaaaat taggacgaga tgatatagga acacatacat
     2281 taagaaaaac ttttgggtat cactactaca agaaaactag agacattgct accttaatgt
     2341 ttatttttaa tcatagctcg caagcaatta caaaaaggta cattggtata actgaagatg
     2401 aaataggagc atcacttcgt ggatttaaac taggtgtata atttaaaaat ttttataaac
     2461 agtaaagaca aagattaaaa gctattttta tctagaacga ttttatttca taaagttcgc
     2521 ggaataaaag ctggggttac tggtacttgg tataggttcg tgttatataa actaagtaat
     2581 taaataacat ttttaggttg gaaaaggatg aaattaaaaa aagagaatca atacggtctc
     2641 aaaaacgcaa acgctgcgga ataagaaaaa tactgataac tcaacgttta gcagactatc
     2701 taatagggat agtctgcttt tttcgttttt gaccatactt ttgaccttct gcaaacttcc
     2761 ttgcttttcc tctgtagaac tcatgaaatc tgcaaaacga attgccgttt cctctgtctg
     2821 ctttttcgcg atatgggtgt atatatcatc catagtggtt ttaatatctg tatgtccaag
     2881 tcgaacatac acttctttga cagacgcacc agattcaaag agcagactac aatgggtatg
     2941 acgaaaacca tgaagtgtga tatgttttaa gttattctct ttaatgatga ttttcaaatt
     3001 gtgatttaca tagtctaaat aaaggggctt attttcttct gatgaaaaca aaagttgttc
     3061 accatctttt ataggtttga ttctcatttt tagatattat gcccgcacgt attcatcaca
     3121 tttctattgt gaatcgcttt attcgaccga catttgactt ttatcataat atactcggtt
     3181 taaaattact aatgaaaaca attaatcaag acgatcatac catgtatcac ctgttttttt
     3241 cagataatca ccaccgtgtg ggaactgaac tgactttttt tgaagtacaa gaagggaaca
     3301 accagttttt tggaaccaat acgattgaac gaacgatact aaaagttcct tccgaagcat
     3361 cattgcattt ttgggaaata tattttgaaa cacaaggcgt ttgccattat ggaatcgaat
     3421 cattttctgg acgacctatc ttacgttttg aagggccaga tgcaacacga ttagctttag
     3481 ttcccttacg cgaatttgaa gatattgatg attatttccc gtatgtcaca gaccagatcc
     3541 ctacagagca tgccatttta ggaattgatg ccattcaact acgcgtacaa tattccgatg
     3601 cgactgaacg agagttattg tcggtaggct ggtagcacaa agaatacgtc agtttctttt
     3661 cgggtcatca acgagtgaca atcttagaaa atcaagacac tcagttctat caagaagttc
     3721 agattattca agatcgtgag aatccagttg ccattgaagg gattggtagc gtccatcatg
     3781 ttgcgtttgg cgtagaaaat aaatctgatt tacaacgcat cgacaaacaa ttacaagagc
     3841 gcaattttat aaattcagga ataaaagatc gtgaattttt tgtatcactt tattatcgtg
     3901 acccaaatca attattgatt gaaattgcta caggggaagg aaacctagat gcaaaagcgt
     3961 atgaaaatca aagtccacgc tttgaagaaa ttcctttatt tttaccgcag tacttaaatt
     4021 tcattcgtga acaagtggag caataattag ctaatcaaat ccatgacgaa gagtaagagg
     4081 ttgactcata agtcaaaaaa taaagaaaaa cgcatcaaat ccattctaaa gaatgttgat
     4141 ttgatgcggt tcctattttt ataaactatc attttcgact aataaaacta cttatgagtc
     4201 agcctctctt tttttcttga tttttatacc tctttctagg taaactaaac atctgccaaa
     4261 aataccgtgt ctcattgaaa cattctcaac tatttcaaaa taaaggggag taccaaatga
     4321 acgagtatat tgaaattatc cacgcaagag aaacaactta aaaatgtcag tctcaaaatt
     4381 cccaaaaata aaattagtat ttttaccagc gtatctggtt caggaaaatc atcgattgtt
     4441 tttgatacta ttacccaaga agctggtcgt caactgaatg acacctatga tagttttacc
     4501 cgtttatttt tacctaaata cagtcgtcca gaggttgatg agattgataa tctttctacg
     4561 gcgattgtgg tcaatcaaaa gaagattggt ggcagtgcgc gctcaacgtt agggacgatt
     4621 actaacatca atgcgttatt tcgtgtgttg ttttcatgtt ttgcaacacc tagtttagga
     4681 tatgcaaatg cttattcatt taatgatcct agtggaatgt gttctgtctg tcagggaatc
     4741 ggtaagacga ttgcattttt aataggattg ctttattttt cggctattga taatgctgat
     4801 tttgtatttt ctgatccatt taccgcagaa gttttgtctg gaattgagga acaggcaaag
     4861 aatcatggtt attttgtatt ggtgcataat gttaattcag cagaagatgt taaaactatt
     4921 cagagaaatt ggcgttttga ggggttcatt gttgttggtg tacgtgtaaa agaatttttg
     4981 gaattaaata acgtttttga tggtcctgtt gtttatattg atacgcatct ttcaaaagag
     5041 acattaagag aacttgaaca acaaatgaat cgtttatttg taaatacaaa tgattaccaa
     5101 gctagtacat tggcagtgga acatttgatt cattatggtc atgagaaaat agcgtttctt
     5161 tcttttgact acattgtagg tgaaccaagt gttattcaag aacgacatca agcttatatc
     5221 gatacattaa agaaatatca tttaaccttt aaatcgcatt ggatatataa caactctgaa
     5281 tttgagcgaa tttatcaaga attagctgaa tttactgcaa ttgttgttac tggagattat
     5341 ttagcggcta aattagtaaa atttttaaaa aataagaata aacgagtgat ggaacaatta
     5401 tcgattattg gatttgatga tattactttt gcagaattaa tggatcctgc gttgacaaca
     5461 atacgactaa atccaggtaa caagggggcg attgcttttc accaactgat tggactggcc
     5521 aaacaagaag aaataaaaaa tcaagtacta ctattagagg gagaattgat ttctcgagac
     5581 tctgttcaca aaatcaaata aaaaagctct gtgaaataag tatagttaac aataaaatat
     5641 ccgaacgata gagagaatga actgtgatct agcagttcct cgtcgcaaat tcactagaat
     5701 tagcattatt tactctaaat tgttcggata ttttttcttg tttttaatta tgattacagt
     5761 gcctattttt aacgaaattt gcttattttc aaaatgtatg attatatgtt agtaaacact
     5821 ttcaaatatg aaaagaggag ctattatggt aggaattagg gatgttgcaa aacgggcggg
     5881 tgtgtccatt gcaacagtat cgcgcgtgct aaatgaggat ccgacacttt cagtaaccga
     5941 tgaaaccaaa cgaaagattg cagaatcggt taatttttat cattatgtca aaaaaagtcc
     6001 cgttgcaaaa aatttaacaa atattgcatt aataacgaca gtttctgaag tagatgagtt
     6061 ggaagatccc tattttcgaa cgattcgcag agggattcaa gtcgaagcag aacaaagcaa
     6121 agtcaatttg aagaaaatta ttcgtttgtc agaaacaccg ttggagcaag acgatttgct
     6181 aaaatgtcaa ggtgtgttga ttattgggca ggtgctatct tctgtgattg aagaagtatc
     6241 agcaattaat tcgaatgtcg tagtgattga tgaccctagt attgaagctg aagtagatgc
     6301 agtttatact gatttaacaa aagcaacgaa tcagcattta gatcgattgt ataaaaaagg
     6361 acaccgaaac attgcgttta tcggaggagg acgtgttcgt ttagatagcc aaggaaataa
     6421 acacgtgtca gatgatgatt atcgaaaaat agcctatgag acgtggatga aacaaaaagg
     6481 attagaaaaa tatagtcaaa tttatttaga aggctggacc acacttgacg gaatgcaggc
     6541 agcagattta cttttgaaaa aacatgctaa agataagttg ccgactgcta tcatggtagg
     6601 aaatgatcct attgctgtgg gggtttatcg ttcacttcaa aaaaatggtc tacatattcc
     6661 agaagatatt tcgattgtga gttttgataa tattgaagtt gctgaatttt taacacctgc
     6721 attaaatacg gtgaatgtga atacagaaga aattggaaaa ctagcagttc gcatggttaa
     6781 tgaacgaata aaagaagtta gaaatgtttc gatcaaagtg attgtttcta ataatattat
     6841 tgttagagaa agtgaaaaaa atatcgatta aaaaagtaaa catccaaaaa agggtgttta
     6901 cttttttgtt tactaatatt tttagtaaaa aatctcgaca aaacattaag taaacagtta
     6961 tggtgttgtt aacaaaaaga aaacgcattc aaaacaggag gaattaagat gaaacatttc
     7021 aaaaaaatag ctttaacagg gatagctgtt ttaactggga cattactcgc agcatgtggt
     7081 gggggagata gtaattctaa agacgggcaa gtaactttaa gctatgcgag ttgagatact
     7141 gaccaagctc caggactaag aaaaatgtta gatgaatttg aaaaacaaaa tcctgatatc
     7201 aaagtagaaa tggagacaac gccttgggat caatattggg ttaaattaga agctgcaaca
     7261 acgggaggta atatgccaga tgtagtaacc atgcactcta gcgaatccta taaatatatg
     7321 tcacagaatg ctttgatggg acttgatgat gttatcaaag aaaatgatat tgacatggga
     7381 aactttactg aaggaattgc tgatttctat acgcttgaag acgaactata cgcaatccct
     7441 aaagatgctt ctgtagtggg gctatggtac aacaaagaat tatttgataa tgcaggtgtc
     7501 gattatccag atgaaacatg gacatgggaa acactcagac aagctgcaat tgatttaaca
     7561 gatgaatcaa aaggcatcta tggttttgca tcacatattg gaacagagac tggctactgg
     7621 ccatttattt atcaaaatgg gggagaagta tttgccgatg acaatacaaa atcaggtttg
     7681 aataccccag aagcacaaga agctttagct ttttatcgag atattgcact tgttgatcat
     7741 gcttcaccaa caattacaga attacaagat cctgataagt taagtcgttt tcaatcaggt
     7801 agattagcaa tgatgattga aggaaactgg tttgcaccgg gatttttgaa aaatgactat
     7861 ctagttgaaa atgttgcttc tgccgtgtta cctaagggaa aagttaatgc aacaattaca
     7921 aatggacttg gttgggctgc cagtgcgagt acaaaatacc cagaagaagt gaaaaaacta
     7981 atggcatttt tagctagtga ggacgccaat aaaatccaag cggaaacggg ggcatcaatc
     8041 ccagcactaa aaggctttga agacgagtgg gctgcttctt cagatacaat tgatttgagt
     8101 gcttttggaa aaatgttgga gtatggagtc cctcgtccat acaataaaga tggattacga
     8161 gctgaacaag cagaagttca aattattaac cgtattctgt ctggtgaagt aactgttgaa
     8221 gatggaaccg ctcaaattga aaaagaagtc aatgcgatat tgagcggaaa ttaaattagt
     8281 taattataca atatacaggc gaaaggattc tatttcgtct gtatattaat ggatgaatac
     8341 caaaaagggg gatattatga aaaatcgaat ttttggaaaa tatcgtaaag atcaagtgat
     8401 atggggctat atttttattt ttccaacggc attaggatta attttattaa atatatggcc
     8461 agcaattcaa acagcaattt taagttttca aaaaacggta gggttcggtg atactgaatg
     8521 ggtcggatta agaaattacc aaaaaatgtt tgcagacggt gaagtttttc agtctttatt
     8581 aaacacatta atttatgcag tggtttcgat acctagtatt gttgtattat ccttgttggt
     8641 ggcagtttta atgaatagaa aagttaaagg attgtcgatt tatcggacaa tttattttct
     8701 accagtcgtt gctgcaccat ccgcagtcgc aatgatttgg cgctggatgt tcaataatga
     8761 ttatggactg attaataaca tgttggctaa aataggtctc gatggaccag catggttaac
     8821 ggatccatcg attgcgattt attctattat cattgtagga gtttggagtg ctattggtta
     8881 taacatggtg ttattactag ccggcttata agaaattcct aaagattatt atgaagcagc
     8941 ggaaattgat ggtgctagtc caatccagca gtttttcaac attacgttac cattagttac
     9001 accaacatta ttttttgtag ttgtaacaac agttatcaat gctttccaag tatttgatgt
     9061 tatttttatg atgattactc ctaatagtac cgccatgttt aaatcacaat cattagccta
     9121 tttattctat aaacattcat ttattttaaa tgacaaggga tatggttcgg caatcgttat
     9181 gttcctttta gtgattatat taattattac tgcaattcaa atgaagttgc agaaaaagtg
     9241 ggtaaactat taaggaggct atcaaattat gaaaaataaa tttttttcaa atgcgccaat
     9301 ccatatcatg cttattttag gtggtattgc aatggcatta ccttttattt ggatgatttt
     9361 aacttcaggg aaaacgttgg ttgaatctac ccaaattcca cctacaattt tccctgagaa
     9421 atttcagcta agtaactatc aacaagtact tgatttatta ccattcatgg ctttttatat
     9481 caatacattt ttaatggttg ttggacgagt gattggctcg gttttatttt cagcaatggc
     9541 tgcatatgct tgtgcgcgtc taagttttcc agggaaaaat atccttttca gcttagtact
     9601 tattcaaatg atgattcccg gttccatttt tattactcca cagtatttat tagcacaaaa
     9661 attgggtatt ttaaatacaa ttccagcatt aatattacca ggggtagtta gtgcgtttgg
     9721 tacgttttta ttaagacaat ttttcttagg tttacctgat gaattggagg aagcggccta
     9781 tttagaaggt gccaatattt ggacgatctt tttcaaaatt atgttgccgc ttgctaaatc
     9841 aggattggtt gcacttggaa tattcacagc gttgtttgca tttaaagatt taatgtggcc
     9901 attgattgtc aatacttcaa ttgataagat gcctttagct ccgggattag caaacttaca
     9961 aggacaatat gccacgaact tcccacaatt aatggcaggt tcgttattag caatttggcc
    10021 aatagttgtg atattcatcg ttttccaaag aaaattcatt gaaggaattg ctacaacagg
    10081 tagtaaatta taaaactatt aattagtgat tggagagtaa gtacatgaca aaaattacat
    10141 ttattggtgc aggaagtact atttttgcaa aaaacgtatt aggcgatgcg atgttaactc
    10201 caagtctaca agatgcacat attgcattgt acgatattga tgaaaaacga ctaaaagaat
    10261 caaatttaat gcttaaaaat attaataaaa attcgaatga aaatcgtgct gatattgttt
    10321 cttattatga tcgcaaagaa gcgttaagag aggctgattt tgttatcaat gctattcaag
    10381 tgggtggtta taaaccttca acagtgattg attttgatat tcctaaaaaa tatgggttgc
    10441 gacaaactat tggtgacacc atggggattg gtgggatttt tagaacccta cggacactac
    10501 cagtaatgtt agactttgct aaagaaatgg aagaagtttg tccaaatgct tggttattga
    10561 actatacaaa tccgatggcg atgttaacca tgggtgtttt aaaagcgacg agtattaaga
    10621 ctgttggttt atgtcatagc gttcaagtat gcgtaccaga attgtttgag catttaggaa
    10681 tagccgatca atatgactta aatgactttc aatggaaaat tgcaggcatt aatcatatgg
    10741 cattcttgtt ggaaattaca aaaaatgggg aagatttcta tccaacaatt cgtcagttag
    10801 ctgcagaaaa accaaatcca catccagatt ctgtacgttt tgaattgttg aaacgttttg
    10861 gttactatat tacagaatca agtgaacaca atgcagaata ccatccatac tttattaaat
    10921 caaaataccc agaattgatt gacgaattag ggattccgtt ggatgaatac ttacgtcgtt
    10981 gtgaacaaca aattaatgat tgggaaagca tgcgagagga cattgtaaat aatggggagt
    11041 taacacatac gagaagccgt gaatatgctt catatatcat ggattctatt acgacaggaa
    11101 ctccgtcagt gattgcagga aatgtcttaa ataaaggctt aatcacaaac ttaccgacag
    11161 atgtttgtgt ggaagtacct tgtttagtcg ataaaaatgg cgtgcaacca acctatgtcg
    11221 gtgaattgcc aacacaatta gctgctttaa atcggacgaa tatcaatgtt caagaactga
    11281 cagtagaagc cgctttaaca ctagataaat caaaaattta tcaagcagcg tatttagatc
    11341 cacatctatc atctgaattg tctttaacag atatcaaaaa tttagtggat gatttaatcg
    11401 aagcacatgg ggactattta cctgaatata attaaaaaga agctgaaaga gtaaggaatt
    11461 ttcaattcct tactcttttc ttagttaaat ttagtaaaaa tattgacaaa acacttagta
    11521 aacagttaca ttagtgttaa caaaaagaaa acgcattcaa attgtataag gaggagcata
    11581 aaatgaagtg gtctaaaaaa attattttag cttgtatagc actaggagca acgatctctt
    11641 tgactgcttg tggaaaaaat caggaagatg caagcggtaa ggtagaaata gagtttttta
    11701 atcaaaaaaa agaaatgact caaacgattc aggagattgc taaagatttt gaagcaaaaa
    11761 accctgatat tcatgtaaaa gttgtggatg taccgaatgc tggtgaagta attaaaacac
    11821 gtatgcttgc aggcgatgta ccagatgtca ttaatcttta tcctcaaagt atagaattga
    11881 aagaatgggc gaaagctggt tatttagagg acttaaccga agaaccgtat ttagagaata
    11941 tcaaaaatgg atatgcacaa cgttttgcta ttgaggatcg tgtatatagc ataccattaa
    12001 ccgctaatgt ctatggtttt tactataaca aaactgcttt tgaggaaatg gggattcaag
    12061 caccagaaac ttgggcagaa tttgaaaaaa tagtagctga gattaaagat caaaacaaag
    12121 taccgtttgc gattgcagga gcagaaggct ggactttaaa tggttatcac caactagcta
    12181 tagcgactgc tgctggtggt gaagaggaag cgaacaatgt ttggcgtttc tcagaagtta
    12241 atggaattaa tgctgaaagc aaagaaatgc aaaaagattt taatcgatta gatttgttaa
    12301 gagaaccaaa agctttgcaa aacaactggc aaggtgccgg ttataacgat acagtagtta
    12361 cttttacaaa aggtgatgcg ttgattatgc cgaatggttc atgggcaatg ccgatgattc
    12421 attcacaaaa tccagatttt gaagtaggaa cttttccttt tccagcagat gaagcaggtc
    12481 aaagtctaac gattggcgca ggagacctag ccttatcagt ttctgcaact tctcaacata
    12541 aagaagaagc caaacgtttt gtagaatata tgacaacacc tgaagcgatg cagaaatatt
    12601 atgatgtaga tggtgcaccg tgtgctgttg agggcgttat cgagaatact caggattcac
    12661 cattaagtgg tttaactgaa cttgctttta ctgatcgtca tttagtttgg ttagccaaag
    12721 attggaatag tgaaaatgat ttttatacct taacaacaaa ttatttacac aatggcaatc
    12781 aaaaagccat gattaacgca ttaaatgctt tctttaatcc aatgaaagct gacggaaggt
    12841 aggaaaataa aatgaaaata aaagaaattt taaatcgtta ctgggcaatc atttttgtag
    12901 caattccaat tattttgcag atgatttttt tctactttcc aatggttcaa ggtgcttttt
    12961 acagtttaac taattggact ggtctgactt ataattttga ttttgtgggt ttgaacaatt
    13021 ataagattct tttttctgat ccgaagttta tcaaatcgat tggcttcact ttaattgtga
    13081 cgctttgcat gattgctgga caaattggtt ttggtatttt gattgcgcgg gcgttgaacg
    13141 caaatattaa agggaaaaca ttctttagag catggttctt ttttccagcg gtcttatcgg
    13201 gcgtggttgt ttctttagta tttaaacaaa tttttaacta tggtttacca aaaattggta
    13261 gtatgttagg cattgaattt ttacaaacca gtcttttagg aacaacatgg ggagcgattt
    13321 ttgcagtaat ttttgtttta ctttggcaag gaattgccat gccagtcatc attttcttag
    13381 cgggttttca aagtattcca caagaaatta ttgaagctgc tagaatggat ggggcgaatg
    13441 ataagcaaat tttttggaat attgaaatca cctacttatt accaagtatt tcaatggtat
    13501 ttattatggc attaaaaggt ggcttaacag catttgatca aatttttgct ttaactggtg
    13561 gtggaccaag cgatgccaca acatctttgg ggttacttgt ttataattat gcttttaaaa
    13621 acaatcagtt tggttatgcg aatgctattg ctttagtctt atttatctta attgggattg
    13681 tttcactggc acaattaaaa ttatcgaaaa aatttgaaat ctaggaggtt tcccaatgaa
    13741 aacatcaaaa gaaaaaaata tttctaaata cttgctttta ttattagggg gcttcatgat
    13801 tttagttccc ttagtttcaa cgctattcgg ttcatttaaa acaacacccg atattatgaa
    13861 taatttcttt cgttttccta atccagcgac tttggaaaat ttccgaagat tgttagcgga
    13921 tggaattggt cattactttt ggaattcggc aatcatcaca atcattgcag tagttgctgt
    13981 gacagcaatt attcctatgg ctgcttattc actagcaaga aaaatgactc gtgggaaagc
    14041 atacggattg atgtatttat ttttaatttt aggaattttt gttcctttcc aagtaattat
    14101 gattccgatt accgttatga tgagtaaaat tggtttagca aatatgtggg gattaatctt
    14161 actctatctc acttatgccg taccacagac actattttta tatgttggtt ttattaaact
    14221 aaatgtgcct atcagtctgg atgaggctgc tgaaattgat ggggctagtc actttacaac
    14281 ttatttcaaa attgttttcc caatgttaaa accaatgcat gcgacgacta ttattcttaa
    14341 tgctctatgg ttttggaatg atttcatgct accattatta attttaaatc gtgattctaa
    14401 tatgtggaca ctaccattgt ttcaatataa ttatacggga caatatttta acgactatgg
    14461 tccaagtttt gcttcctata cagtaggaat tgtcacgatt acactagttt atcttgcttt
    14521 ccaaagaagt attatagctg gaatgagcaa tggagcagtg aaataaccaa taaattattc
    14581 tcattataaa ggagttcata aacttatgat tatatttgac aatcacacac aaacatttca
    14641 tttacaaaat aaaaaaatta gctatctatt aggaatcgaa gaaaataatt atttaacgca
    14701 tctttatttt ggaaaaaaga ttacgcacta ttctggtggg tatcgctacc cccgaacaga
    14761 tcgttccttc tcacccaaca atgcaaatgc gcaagatcgt ttattatctt tagacacatt
    14821 accattagaa tttccaggat atggacatgg tgattttaga gaaccggcgc ataatattaa
    14881 attaggaaac ggtagtcgtg taaatgattt tcgttatgat agctacgaaa ttcaaaaagg
    14941 aaagcccagc ttagcgggat tgccagcctt atatacggaa gatgatgatg aagctgaaac
    15001 gctgattatt caattgaaag acgcgattag tggattgact ttacagttgt tctacacaat
    15061 ttatcaaaat cacagtgtaa ttattcgttc tacgcaatta gtaaataata gtgatgaaac
    15121 agtggagatt aaccgcttag ctagtcaatc aattgatttt ccaaatcgtc cactcgagtt
    15181 aattcattta aatggtacct gggcaagaga acgtcaaatg actagagaaa aaattcatac
    15241 agggataaaa gtattagata gtaaacgcgg atcaagcagc catcaacaaa atccgtttgt
    15301 tgctttagta gatgccaaaa cagatgaatt tcaaggagag gcatatggat ttaatttagt
    15361 ttatagcggt aatcacgaaa cggtgattca aaaagatcca tttgaccaaa cacgggtcat
    15421 tatgggaatt aattcattta attttggttg gcaactaaaa actggcgact catttcaaac
    15481 gccagaagtc gtgatggttt atagtaatga aggtctgaat acgttatcac agacgtatca
    15541 tgaattgtat aatcaccgtt taattcgtgg aaactatcgt ttaaaagaac gtcccacgtt
    15601 aatcaacaac tgggaagcaa cgtattttga ttttaacgaa gaaaaaatca tgaatattgt
    15661 cgatgatgcg aagaacttgg gcattgaaat gtttgtttta gatgatggtt ggtttggcgg
    15721 tcgtgaaaat gacttcactt cattaggtga ttgggttgaa acagaaggca aacttgcttg
    15781 tggtttggaa aatttagcca agcaagtgca tgataacggg atgaaatttg ggatttggtt
    15841 tgaaccggaa atgatttctg aagatagtga actatttcga gcacatccag attgggcatt
    15901 gggtattcca ggtcgtgacc gctcaattag tcgaaatcaa tatgttcttg atttttcaag
    15961 acaagatgtt cgtgataata tctatcaaca aatgacggcg atttttgatc gtgtaccgat
    16021 tgattatgtg aagtgggata tgaatcgaaa tatgacagaa gtctattctg tcttgttgga
    16081 ctcaacgatg caaggtgaag tggctcatcg ttatatgtta gggttatatg aatttttaga
    16141 aaagttaaca acgaattatc caactatttt atttgaaagt tgttcgggtg gaggcggtcg
    16201 ttttgatgca ggtttcttgt attacatgcc acaaacttgg acgagcgaca ataccgatgc
    16261 cgtggctcgt ctgaaaattc aatatggaac cagcttagtg tatccaattt caagtatggg
    16321 tgcgcatgtt tcagcagtcc caaatcatca aacaggaaga gaaacgagtt taactattcg
    16381 tggcaatgct gcgatggctg gtgtttttgg ttatgagcta gatctaacgc aattaacttc
    16441 tgaagaaaaa gcagaaatta aagaacaagt tgccttttat aaaaagcatc gccaactttt
    16501 gcaatatgga actttttatc gcttggaaag tccgtttgaa ggcaatgata ctgcatggat
    16561 gtttgtctca aaagaccaaa cagaagccat ggtcttttat ttccgagtat tagcagaagc
    16621 tgcgcatcca ttagtcacat tgaaattagc aggattagca gaagaagcaa cttatcaaat
    16681 ggaagatgta acatttgctg gcgatgaatt gatgaatctc ggtttttata ttgactcaga
    16741 actacatggt gattatgcga cacaacgctt ttatttgaaa cagatatagt agcttgaatt
    16801 tacaatataa gtgcaacacc aaaagagact cattccaaac gaagaaaata tgttttattt
    16861 acacgcattt actaaaaagc agcctgattt gaattgggaa aatgaagaag tacgtgaaga
    16921 aatctatgca atgattaact attggttaga taaaggacta ggcggattta gaatcgatgc
    16981 gatattaaac atcaaaaaaa aactagagta tggcatcttt gaatctgatg gagaagatgg
    17041 gttagccttc attgggccct ggattcttaa tcagtcgggc attgaagtgt ggttaaaaga
    17101 aatgagagag cggacattta aaccacataa tagtatgacg gtagcagaag ccgatgttcc
    17161 taatgaacgt ttagatgaat atattggtga agatggctat tattcgatgg tttttgattt
    17221 tagttatacg gatattgatg tacctgaaac tggtgaatgg tttaaagata gccaatggac
    17281 atggacggat atgcgtacca atatttttac gaatcaatta gttacgcaag ataaaggttg
    17341 gggcgcctta tatttagaaa accacgatca accacgttca attaataaat atattccaga
    17401 agaatggatc aatgattata gtaaaaaaat gttggcgacg ctttttatgt tactaagagg
    17461 tacccctttt atttatcaag gacaagaact aggaatgacc aacatagaaa tggcatcatt
    17521 agaagatttt gatgatgtag ctacgcattc tcagtataaa cgggcattag aatatggatt
    17581 ggcaccagag caagcattga aagctgtcaa taaacgaagt cgggataatt ctcgcacacc
    17641 tatgcaatgg aatacgcaaa aaaatgccag attctcaact tctgataatg tatggttaaa
    17701 agtaaatcct aattatccag aactcaatgc agaagctcag ttaaccaatc aacagtcggt
    17761 attcaattat tatcatcaat taattaaatt aagaaaaaat agtgtataca aagacgtgct
    17821 aatctacgga caatttctac cagtgaaaga taaaaatgaa catattttgc tttatgaacg
    17881 ccaattagaa gataaaatcg tattagttat cttaaacgtt acagcaacag aacaagaata
    17941 ttatgtagat gaacagtacc aacaagtatt aatcaataat tatgaagatg ttttattaga
    18001 tcaaagtcga aaattgcgtt tacgaccgtt tgaaagtatt gtattagcta attatggagg
    18061 acaattatga aaattaaaaa cgaagcaatg ctcatcacct atgcagatag tttaggaaaa
    18121 aacatgggcg aattaaaaca agtcttagac aaacatttac aaggtgttat tggtggtgta
    18181 catctgttgc ctttttttcc atcgacaggt gatcgaggct ttgcgccgag tgattatacg
    18241 acagttgatc cagctcttgg aacatgggaa gatgtggaag cattaggtga agattattat
    18301 ttgatgtttg attttatgat taatcacatt tctcgtgaat caaaattttt ccaagatttc
    18361 aaaaaaaacc atgagcagtc accatacaaa gaaatgttta tccgtattca tgaatttttc
    18421 ccagaaaatc gaccaacaca agaagatatt gatttaatct acaagcgtaa agacaaagcg
    18481 ccgtttcaaa cggtagaatt tgcggatggt acgacagaag aggtttggaa tacctttggg
    18541 gaagaacaaa ttgatttaga tgtgaccaaa gaagttgtga aagaatttat tcgagaaacc
    18601 atcaaagata tggcgaacca tggctgttct ttaattcgat tagatgcgtt tgcttatgcg
    18661 attaaaaaat tagataccaa tgatttcttc gtggaaccag atatttggga acttttagac
    18721 gaagtgcgtc aagaagcagc gaaatatgac gtcgaattat taccagaaat ccatgagcat
    18781 tattccattc aaatgaaaat tgccaatcat gattattata tctatgactt cgccttgcca
    18841 atggtcactc tgtattcact ttatagtgga aaatcagaac gtttagccaa ttggttgaaa
    18901 atgagtccga tgaagcagtt tacaacattg gatacgcatg atggaattgg tgttgtggac
    18961 gctcgtgatt tattaacaga tgaagaattg gattacacct ctgaggaatt gtataaagtc
    19021 ggggcgaatg tgaagaaggt ctattcaagt gccaattaca ataatttaga tatttatcaa
    19081 attaacagca cctattatag tgcattaggc gataatgacc gtagctatct gttagcacgt
    19141 gcgattcaag tatttgcgcc agggattcca caaatttatt acgttgggtt attagcagga
    19201 aaaaatgata ttgaactgtt ggaagcaacg aaagaagggc gtaatattaa tcgtcattac
    19261 tatgatttag ccgaaattga agaagaagtg caacggccag tgattcaaca attatttgca
    19321 cttttaaaat ttagaaatga atctgcggcg tttgatttgg atggaacgat tgaagtagca
    19381 acgccatcag aatcagaaat agtgattaca cgtaaaaata aaaacggtag tgatagtgca
    19441 acattaacgg ctaacttgga tacgaaagaa tttatcattg agtctaaaga tataaaaatt
    19501 ttcactagtg ttgcattaaa attttaacct attccataga acaaaaaatc ctttatacta
    19561 gcacttggat gacttatcca agaccaataa aaaggactca tacatggata agtataaaac
    19621 aaatacagca tttaataaat ggttttctgc cataaaatta ggaaaacttt ctgtcaactc
    19681 ccaaaaatgt atttttgatt acaattcgta tcgtaaaaaa ctgtcttttg aagctgtgct
    19741 caagctcttt ctctacgcag ttaatgaaga aaaagaaagt ttgcgtgatt tgagtacagc
    19801 tcttatcgac cgatcgctcc aactagaaac cgatgtgtca tcgattagtc atacccaatt
    19861 gtctcgagca tttaatgcac ttgaacctaa agtgttagaa gaaatttttc aacaactgtt
    19921 agaaaaagtt caacatcaaa tcaaaccaac caagcgaaat catctgtatc tgattgattc
    19981 cagtacgttt tcgcttagtt taaaacgtca taagtgggcg actttccgtc aaacaaaatc
    20041 aggtgtcaag ttacacttaa actattgtta tatggacgat actacgatgt atccaactga
    20101 ttttacctta acaaatgccc atgaacatga tctcaatcaa ctaccagtat tggtgaatca
    20161 accagaggca acttacgtgt ttgatcgtgg gtattaggac tttgaaaaga tggatcagat
    20221 gcattgggat ggctatttct tcgtcactcg gattaaaaaa aacaccaaag ttcacgtgat
    20281 agatactctg gaaacatcgc cagaaacaga aattctacga gacgagctgg ttcgtttagg
    20341 atctaaaacc tatctaaccg ccaatttccg actagtcact gttcaagata agaacggacg
    20401 tgtgtttcaa tttatcacca atcgaatgga cgtctcttca aaagaaatct ctgatatgta
    20461 tcacgctcgt tggcaaatcg aattgttttt caagcacatc aaacaacaca tgaccattaa
    20521 aaccttcttt tctcaaagtg aaaaaggcgt gcagaatcaa ttgattttaa cgatgatttc
    20581 cgctctcctc acgtttctca tcaaattgga gacgaaaacg gaaaaatcag tgttccaaat
    20641 caaacgattc tttcgttatt tactgtttca gccctttgaa tgttgtctag aaaaattaat
    20701 tcccacatga gaaaaaagaa atttggctcg ttacttttgg ttttcagttg aataacagat
    20761 aaaaaatttt ctggaaaaag tcatcctctg cgtcagcaca gttttttttg acttattttc
    20821 agaggaaata gttttcagaa tattctaaaa tgttttatgc aacactagtg atatttttta
    20881 gaattagatt tctaatgtgc attttttgag tattaaggag caagtataca aagatttata
    20941 aagctgatta aatttgaata aaaatatgca ggaacgctac tatttttagt agtgttcttt
    21001 tttatatttg aataaaaaat gtggtggtta aatggtggtt ataacaaaaa atgaattaat
    21061 gaaattaggt tatgggaagt atcagtctga gagaatcata cgacaggcaa aagcaattat
    21121 ggcttcaaaa agctatacct attacgaaaa tagaagatta ggactagtac ctgttgaatc
    21181 tgtagaagaa gttttaggta tgaagataga ggtagaggag gattttcaga atcatggtta
    21241 attttaaaaa agataaaaat gggaaatatc attttactgc tagtttggga ttcgacaaac
    21301 gaacagggaa aagagtacaa aaaaacgtag aggggttaaa acagttaaag aagaaaaaaa
    21361 gcgtataccg aacttgtttc taattatgga aaagaagcag aaacttctca aagtactatg
    21421 ttgtttgagg agttttttta taaattattc ctaccttatt atcaagggaa agtagaagaa
    21481 agaacatata aaaatcggtt atctacaatc aaaaaaactt ttcttatttc tttaaaatgg
    21541 agttaagaga aatacgtcca attgacattc aaaagtggca aaataattta ttgagcaaat
    21601 ataaaaattc ttatgtaaga aacatgtatg ggatttttca gatgtcatta gatcgagcag
    21661 ttgttttggg actacttgaa aaaaatcctg caaaagttat tggaaatgtg aagaaaagga
    21721 aaactacagt tgatttttgg acaaaagaag aatttacaaa agttatttca actttttata
    21781 ttgatgattt gtaccaacat tttggtttta tttgtatgtg gttacttttt atgaccgtta
    21841 tgcgtttggg agaagccact gcattaactt ggaaagatat tgattttgaa aataaaaact
    21901 tgcgtgtgaa taaaacactc tattataaga gagccaaaac ctatgagttt gtagaacccg
    21961 aaacggcttc tagtattcgt acaatcgaac tagacgacaa tacaattacc tttttaaaag
    22021 cttggaagga gcgtcaagtt tcaataggag gcatgtcgtt tgtactttct tataatggaa
    22081 cacctactca gaaatataca atccgtcata ttatgagaag acatgcaacg atcgttggtg
    22141 ttcatataat ccgcatacac ggattaaggc atagtcatgc ttctttgctt atatcacaat
    22201 aaaaagatgc acttcgaatt aaagaaaggt taaaacatgc tgatgtacaa acgactttag
    22261 gaacttatgg tcatttgtat ctaaattcat tgagagagat aacaaatgat cccacagatt
    22321 atatccaaac taatttttct aaaatcaaac cgacacctat ttacgataat aaaaaataaa
    22381 tgataaacaa aagtaggatc acaccaaaag aaacacacta gaaaaactat aatacaggct
    22441 tttctagcgt gttgtttctt atttccgcct atttatacat tatactcata aagcatttaa
    22501 tgcatcgatc gtagccgcat tgtctatatg ggtatataaa gttgttgtat tggtacttga
    22561 atgtcccaat tgttgggcag ttaataccaa tgaatttgtc tgttggtaga gtctagtagc
    22621 taatgtatga cgcagtttgt gagggctgac ttgaattcta aagccttttg aatattttgc
    22681 taccatccgt tcgattgcaa taccggatat acgcttggct tctccttggt aaattgctag
    22741 aaataaagct ttttcgtttt ctgttacttt atatcgttct ttccgaatag ctagataatt
    22801 agctaaatat tccattgcga atgctgctat attgacagca tctcttttat ttccttttct
    22861 agttactacc acattattct tatctaaaga taggtcatct aaattaatat ttataacctc
    22921 ggagagtctc aatccagatc ctaaaatcag tgcattgatc gccaggtctc tttctacatc
    22981 tcgttgataa tagatcaaag ctcgtttact caaagtattt ttatattcat tggcaatata
    23041 atctagataa ttttgtgtat ccttatctag aaataatttt ttctcaatgg cattggcacg
    23101 tgcagctaac gtagttttat ctgtgatggt tgctacttga tccataggat tattgtctaa
    23161 gtatggtttt cctagaggat tattggaact tttcgaaaga tatttaaata gaacctttaa
    23221 tgccgtgata tttctattga tagtagaagt agatagacct aagttattat tatctttgag
    23281 cttagttttt gttgtctctt tttttacatt ttcttttgtg cgacgtttca aatgagattt
    23341 gtacaagttt aggtcatagg cagttaactg tcttatcgag gtgatagaag tatcaggaac
    23401 gatagactca ctcagaagcc attcataaaa gagcttataa ttttttagat attctaaagt
    23461 ggttcgaggt gattgatctt tatcctcacg atcttgaaca aaatctttta tataatcggg
    23521 catatgaagt atgattgtat ctattttttg atatatttct gtatttttca tgtcattcat
    23581 cctttcaata agtaggggag aagagtatct ctataattgg actataccaa ttatagaatg
    23641 ttttgtcaat tggtatgctc taaaatttat taatttgttt caaaaaaagc atataaacag
    23701 gtatacgttt aataatttaa aataaatggt atacataaat agggaaggaa atagaaggga
    23761 gcaatctaaa ttttttgaat tttcttaatt aattatatag aaagaacaat ctttctatag
    23821 agttagacat gagagggact atgcttgatt taaaatcaac aagcgtatat actgtatata
    23881 caaagaaaaa ggagggagaa gactatggca attaaagaaa gaaaatttag ggaagtgggg
    23941 aactcagtag tattaactat ttcaaaggag tttcttaaag aaaatgggtt aaatcccgga
    24001 gatacggttt ttttagatga agaaaaactt cgagcggcaa ttacaaaaaa acaagcctta
    24061 tctgatgaaa ttgatttagc aatatctcaa gcattaactg aatatgatac tacttttaga
    24121 gagcttgtcg ataaatgagt attcattacc tagaagccaa agatattata aaaatgaatg
    24181 taatccaaat aaaaaaatac tctcctaatg aaccccttgg tgtaaaggat gcgaatgctt
    24241 tagaaatgtg tgtagggcaa cttcgagcct cagcttttgg tgaagaggtt tatccttcga
    24301 tttatgaaaa agcagctatc ctacttatac aattgataaa gaaacatcct tttcacaatg
    24361 caaataaacg tactgctttc ttagctactt ttgtcttttt gaaaatcaat ggacagcttt
    24421 tagctattga tcaaaaagat gctgtaaatt tagcggtata tattgctacg tatgataagg
    24481 atttcgatca actaaaatat gaagtgatca acactataaa gacacatacg cagcccattt
    24541 aaggagttac tgtatgtgtc tttatagggt tattagctgc tatagcgaaa taattgaagt
    24601 aaattacaaa tagctataat tcaaatccaa ctatatagaa aacgtaaatt ttctatatag
    24661 ttggattaag ataacgacta tttattttat catattttta ctatacccta tacttttact
    24721 tggtatattt atgaataatc gcaaatttac ccctatacta ctagtttgta agttagatta
    24781 ataaaaatac taaagttatt tgttctttta ttaaatacac ctacaactta taaattgatg
    24841 gtatttagat aacacgaaag aataaaaata acagctgata gtaaagtttg ttgacgattg
    24901 ctactcaatc gaaagtgagt tagtgcgtat gaacttgctt ctgaaaactt atgaaatgaa
    24961 agacctttta catcttgcag aaatcgttac tgggattaaa ctaagcaata aaaactaatg
    25021 ttcccctcat tctttgaact tctactattt gatttattta ttctgataaa tgacgatttc
    25081 accttcagga tcttcaaatc ccgtatagaa tttatttaag atctcttcag tatcagtaat
    25141 aggataggcg ataggccaca taccctttga tggttagaat aaactgctca aaatctgtat
    25201 cgtatgttgg ctttagcata ttaacaaagg ctatctccaa attataaacc ataagcgttg
    25261 aatcgttctt aacaatttca attcttccta acccaaagtc agaagatata attaccggac
    25321 ttgccttacc cttcatgtgg gttgttgaga ttccatattt aaagggaatt gtcggtacta
    25381 tcggcggtct gaaaaacatc ccaaaaataa aaaaatcttt cccctgctag tctcctaagt
    25441 ccctttgtag cggatatggc accataatct cattttatcg aagtgagtca tggtttatct
    25501 gttggccaac caaaattgat acaatctaac gatgcaccct ctacggcatt ctaggggagt
    25561 gcacttgcat tcacccaata aaaaccggca gttagcaaag aacttatgta gtcgtatgtt
    25621 cttactgtta acatacaaga ggtctccttt ccacaattgc ttagcagtaa acgggaattt
    25681 acaaagctaa tctcttccat tttcttatct ttgttctaaa agtcccaaat ggagcaactg
    25741 tatttacatg aataaattta tatacttccc atacagccgt tttggttgcc tcgtctgccc
    25801 attttctttt gtgtgcagtg aatagatctt catcactcat tgaatcaatc atcatgttaa
    25861 tatcatcaat attacgattg agaatttcct ctaattcttt caatggtaga tgtgcatagg
    25921 tatttgtaaa ccacttatat aactctccta actgattcca tttaaattga tcagaaggcg
    25981 ttttaacaga taatccattt ctttcatcat tttcccattt tagaattaaa ttcgtccaac
    26041 caacttgata tgctaaattt tcagcaggtg ttctatccac ttcctcaact cttttatcct
    26101 tcaattcttc aggaatagtt tcaaattcta aaatatattt agtataagtc ctatttattt
    26161 ctttttttaa ttcttcttta tttttatatg ttctcattat attacctcca taaattccta
    26221 attgtctcct ttaattcatc tataatttca tccacgatat tttaatccgt tctacaatgc
    26281 atatctgata tgcattgact gtctaactca tatgtgaatg atttataaaa tatcccaacg
    26341 tctcatctaa agaaatgttg atcgtcagca aggagctaaa aaatacgaat atatttcttt
    26401 tgtagtaaaa tcggactggt ttgcatatca ttttcttcgt aaatatcaaa atcatgttaa
    26461 ctactatcaa ttactaataa aaactaccac tttaagcgtt aagaactgtt aagtttagtt
    26521 aagtgaggat agttcacaaa atccattgtt aaacttcacg aaagtggtaa aactcaaaat
    26581 gctttatata ggattacagc atcgctcttt cttcgattgc gcgttgggta aaaaatatta
    26641 tgaagtaaaa attgacgatg acacgttcct tacggctcat cagatgaaac agctacaaaa
    26701 acgaaatgat caactcgaag aaaatttaat tctaaaaaag cgattgccat attcacgcct
    26761 cgctcgacga actattaaag gtcaagattt acctgaagat catccttttt aggaaattga
    26821 agctttttat gttgcacaat gcatttataa tactacaatg atgttttcac cagatattct
    26881 tctagggtgc ggtgtaatga aacagataca cttgcaaaag aaaattcacc gcgaatttac
    26941 taaaattatg aataattatg ttaatcttcc gaaatttttt tccaaaatta agggatcaag
    27001 ctggtgttat agattgttta aggttggcaa aaaaataact tctttttaaa caattataga
    27061 aaaccgatac tctgttaagt tggttgacac ggtgtcgatt tttatgactt tcttattctg
    27121 aaacttcact aacggacagt acctaaaaag tctatagtat ggacgtttac gagtactatt
    27181 ttatcaaaaa tgctgctcat ttcaacttat atgttttagt gaactacccc cacttagctt
    27241 ggataggcta caattaacta gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac
    27301 caggaggaat ttttatgtct aagagaacac gaagaacttt ttcacaagaa ttcaagcaac
    27361 aaatcgtcaa tctttactta gctggaaagc cacgtgtaga aatcattcga gaatatgaac
    27421 taac
//
LOCUS       DADVXV010000034        25717 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.035, whole genome shotgun sequence.
ACCESSION   DADVXV010000034 DADVXV010000000
VERSION     DADVXV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.035"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            153..2213
                     /locus_tag="KB969_001349"
     CDS             153..2213
                     /locus_tag="KB969_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBB6869344.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2296..2865
                     /locus_tag="KB969_001350"
     CDS             2296..2865
                     /locus_tag="KB969_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6869345.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKSDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3040..3846)
                     /locus_tag="KB969_001351"
     CDS             complement(3040..3846)
                     /locus_tag="KB969_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869346.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3984..5498
                     /locus_tag="KB969_001352"
     CDS             3984..5498
                     /locus_tag="KB969_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBB6869347.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5901..6884)
                     /locus_tag="KB969_001353"
     CDS             complement(5901..6884)
                     /locus_tag="KB969_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBB6869348.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6889..7536)
                     /locus_tag="KB969_001354"
     CDS             complement(6889..7536)
                     /locus_tag="KB969_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6869349.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7621..8253)
                     /locus_tag="KB969_001355"
     CDS             complement(7621..8253)
                     /locus_tag="KB969_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6869350.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8269..8820)
                     /gene="coaC"
                     /locus_tag="KB969_001356"
     CDS             complement(8269..8820)
                     /gene="coaC"
                     /locus_tag="KB969_001356"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBB6869351.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8817..9554)
                     /locus_tag="KB969_001357"
     CDS             complement(8817..9554)
                     /locus_tag="KB969_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBB6869352.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9551..10540)
                     /locus_tag="KB969_001358"
     CDS             complement(9551..10540)
                     /locus_tag="KB969_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBB6869353.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10798..11340
                     /locus_tag="KB969_001359"
     CDS             10798..11340
                     /locus_tag="KB969_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6869354.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11357..12442
                     /locus_tag="KB969_001360"
     CDS             11357..12442
                     /locus_tag="KB969_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869355.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12454..13260
                     /locus_tag="KB969_001361"
     CDS             12454..13260
                     /locus_tag="KB969_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869356.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13261..14088
                     /locus_tag="KB969_001362"
     CDS             13261..14088
                     /locus_tag="KB969_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869357.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14085..15158
                     /locus_tag="KB969_001363"
     CDS             14085..15158
                     /locus_tag="KB969_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6869358.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15586..18282
                     /locus_tag="KB969_001364"
     CDS             15586..18282
                     /locus_tag="KB969_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6869359.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18358..18846
                     /locus_tag="KB969_001365"
     CDS             18358..18846
                     /locus_tag="KB969_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6869360.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18858..19352
                     /locus_tag="KB969_001366"
     CDS             18858..19352
                     /locus_tag="KB969_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869361.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19373..20182
                     /locus_tag="KB969_001367"
     CDS             19373..20182
                     /locus_tag="KB969_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6869362.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20179..21000
                     /locus_tag="KB969_001368"
     CDS             20179..21000
                     /locus_tag="KB969_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6869363.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21051..23150
                     /locus_tag="KB969_001369"
     CDS             21051..23150
                     /locus_tag="KB969_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBB6869364.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23147..24265
                     /locus_tag="KB969_001370"
     CDS             23147..24265
                     /locus_tag="KB969_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6869365.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24304..25182
                     /locus_tag="KB969_001371"
     CDS             24304..25182
                     /locus_tag="KB969_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6869366.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25373..25525
                     /locus_tag="KB969_001372"
     CDS             25373..25525
                     /locus_tag="KB969_001372"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6869367.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8132 a         4471 c         5429 g         7685 t
ORIGIN      
        1 aagttattat tccgattttc ttgaaacaat aaaaaatcaa aaaaaatact ctcctaatag
       61 tccatcttct tttgatttta tttatataat gaaatcatct tatgaaaatt actacttcat
      121 gtttagacaa gagtagggag gactaagaat aaatgtgttc aaaaagacgt tcaaaacaac
      181 taaataaaca cgcttgtcgt ttagataagg aacggtcgtg ttctgaaaaa cactacgtta
      241 agtttatgat gcgcacgatg ctgatcagtt tatctgtagg tgtctatatg catgtacccg
      301 ttcaggcaac gacacaaacc atcaaggtcg tacgtacctc tgtttctgag accactgatt
      361 cccctatcac tattactcat actttcactg atgcaaatgg aaaacagcta cttcctgcat
      421 tgacttccta taataaagtc agttatcctc caacgataaa ccactactgg ttaattccta
      481 acaaaacatt atggacatcg gaaaccggaa gcagtgtgcc gctttctatc ttttccgata
      541 tgactgatcc tacaaaaggt gatcagttaa aacagatcac tgatattttg aatcatgctt
      601 tgacagatat aaaggacggt ggaagcgcac aagtttctta tgtatatgaa aaagattatt
      661 cacagtttga aagaaagaaa atcgatgttc tggcagggac aaaagtttcg atatctgatc
      721 tggtagaaag gctgaagaac gcagatggaa cacaaggaga tatgtccaaa gtaatttcaa
      781 acaatgggaa tatcgtggat acgactaata caggaacatc tactatttcc ttgtcctatt
      841 ttgatccaat tgctttaaaa acaatgactg catctgctgt gatccatgtt cgtgctgatc
      901 aaacagctat caaaggaaaa gatcttcact taagaacagg agagagttac gcccctaaag
      961 atcttgttga atatgtaaca aaaagcgatg gaacttcagg aaataaagaa gaaatcaaaa
     1021 tgaacgggac agtagatact acaactccgg gagaatatcc cgttgtatta acttatatag
     1081 actcgaaaac atcaaatgtg gcagaaacaa cagctgtagt ttatgtagaa gcatctgctg
     1141 cttcatcgac tgtcatcact cattttatag atagtcaaac aaataaagaa cttcaagcag
     1201 aaacacatat gagtagtgta aatcgtattc ctgatttgcg cctacctgct gaattttctg
     1261 atcgagtgcc aaatatagat ttatcgactt atgaacaaaa tgggaaagtc acttctattt
     1321 ctgattggat gcaagcaaac ggattagaca gaaaaagtca ctggtcggag atccttgaag
     1381 tacttcactc agaactgatg aataatagga agcaatcagg aggggaaatt acctttactt
     1441 atgtttatat accagacaat cgttcattag aaggtcatga tcttattgtt catccaaacg
     1501 aaaaaataaa caaagaagag ttgatccaat cagcaacaaa ttccttaggt aaacccgtac
     1561 cgttaaagga tgtatcggtt acaatcaatg aagtaccatt ggaggatggt tatttgacca
     1621 aacaaacagg tgattttacg attatgtata gttatcatga cccgtattca ctccaagaac
     1681 tccatgctca gtcactatta catgttttac cattaaacaa acagatagat caaaaagaac
     1741 aaaaaagaca agaagaaagc ttgtcagaaa aaaaacaaca aatggctcat gcagtttctc
     1801 caacagggaa agtaaaacaa acaagaagcc tagagttagc aagaatatct agaaaaatct
     1861 cagaatctaa taaaacgata aggcaagaag ctcatttggc cccacaagtt tctggattgg
     1921 aaaatgaaat tttagagcct aaaataaaac aacaatcaga aaaagaattt gttgctaaac
     1981 agtcggaaga tcagaaggaa tcagatgacc agaaggaaac gaagaaaaaa cgcttgtcaa
     2041 ctattgattc caccgatgag catctgcagc cgcaagtacc acttcctagt ccgggaacac
     2101 ccgcacctgg tggaggtatt ccttcttctg ctttaggaga tttcatgcga ggtatggcag
     2161 gaacatgggt atacgctaat cgaaatgaat ttgacgcaga tgactggttc tgatttatat
     2221 ctctatctgt tatagtcaaa taagtagctg agtcatatgt tatttggcat aatggagacg
     2281 aggagggata gaaaaatgtt agataaaacg ttaccttacg cagaaatctg gatgacaaga
     2341 ccacttcaac aaaatgttcc aatcacgcct ttagcggaag gttttgaatt tcgattttat
     2401 caaaaagaag atgaatctgc ttgggcggag attgagactt ccgttgggga atttcaaacg
     2461 acagatgaag cacttgagta ttttcaacaa aactttgctc cttatcctga agaacttgaa
     2521 agaaggatgt tttttgtaga gacaaaaaaa ggagaaaaag tagcaacctg taccgcttgg
     2581 cgaaaaaaat caagagagca agtgtatccg gtttttcatt ggttagcagt gaaatcagat
     2641 taccaaggaa aagggctcgc aaaagcattg actgccagag tcttgcaaga atttcctacc
     2701 ctccatacgg acggaccaat ctatcttcac acacagacat ggagccatca ggcgattgct
     2761 ctttataaaa aaatgggttt tacttttatt gctgaaaatc tagacggcac acctaatcca
     2821 gattatgaaa aagttatgca ggttttaagt aaattagata aataacgaaa tggtgaaata
     2881 agtcctcagt attgggataa aaaacgaaat agtcattcct catatcttac ttttttgagt
     2941 taatactatc ggataactaa tggcatgcca tacattcaaa aaagaagggg cagtgacaaa
     3001 agtattgtca ctgccccttc tcttgttttt tagcatgttt tatcgtttga tttttttagg
     3061 aataaaattc ttgatgaacg taaatttttg gtaatcgttt cgactataga ggtaaccaaa
     3121 tacactgaaa acaactgctc caataaaatt aacaaataaa tccttcatag tatccatgat
     3181 tcccacgtct aagtaaccat tttggatgat tgttttatct gttttaccat ctgcattttg
     3241 actttcaatg attgtccgag tgatatctgg aacatgatag acagtgtttc cgtctttact
     3301 taactccaca ctattgattt gctggatgat cgtatctttt tgcatatcga attgcagtaa
     3361 tttatctgct gaaaattcca caaactccca cataacacca actgtcatcg aaaaacagaa
     3421 ggaaacaact gctagtaata aaggagtcaa gttcatggtt tttgtatttt tattgagcaa
     3481 ataaacaagg gaaaagccga cacccccagc taaaaatccg ctgaatgcat gtagaaaagt
     3541 atcccacatt gaaaaatagc cataaaaatc acttaactct cctaaaactg ttgaactaaa
     3601 aataaaagat aacaaaatga tttctagcat atttggaatc tgtatcttta atatcttttc
     3661 cagaaaataa gggatttcaa ataaaattaa tgtcagtaat aaaagcattg tatttcccca
     3721 gtgttggttc cagacctgat ccactagcat aataacgacg atgatacgta ataaaatata
     3781 gattccgttt gtgattctac ctgcagtttt tgtactgttc gtaaaaaagg ttttcaaatg
     3841 attcataaaa taactccttc atgtatatcc ttaattatac taagaagcgt gtgtttacca
     3901 aagctatatg acttaaagaa aaacagagtt gatattgtga aaaaaatcac ttaatatagt
     3961 ataaggagaa aagggggata caaatgaaaa aattagttgc tggtttatta acagccgttg
     4021 cacttcttgc tatgagcgca tgcggcgcag atcagaaaaa tacagcgcag acaagttcta
     4081 gtacgaagga atctgccgaa gtatcatcag gcgcttctga acaagtatat acagatccaa
     4141 aagaaatgaa agaatcttat gatgtcgtga ttattggagc tggtggtgca gggatggcag
     4201 cagctatcga agcaaaagat gctgggttga atccagtaat tttggaaaag atgcctgttg
     4261 ccggaggaaa cacatctaaa tcatcaagcg gtatgaatgc ttcagaaaca aaatttcaaa
     4321 aagaagaagg aatcaaagac tcgaatgatg ccttctatga agaaacgcta aaaggtggtg
     4381 gaggaacgaa tgataaagaa atgcttcgat actttgtcga tcactctgct gatgcggtcg
     4441 attggctaga tcaaaacggt atcaaactgg acaacttaac gatcactgga gggatgagtg
     4501 aaaagaggac acatcgtccg tctgatggct cggctattgg tggatactta gtggaggggt
     4561 tattgaataa cgtccatgag cgggaaatcc ctatttttgt caacgcagat gtgacagaca
     4621 ttaagaaaaa tggggaaacg gtcaatgaag tgactgtaca tgttcaagga gaagaaccaa
     4681 aagaggtcac cggaaaagca atcgtagtta ccacaggcgg ttttggtgcc agcaaagaat
     4741 ttattgaaaa atatcgtccc gatttagctg attatattac gacaaatcaa gaaggatcaa
     4801 ctggagatgg tatcaccatg attgaaaaat taggtggaca aaccgttgat atggataaaa
     4861 tacaaattca tccaactgtg cagcaggatg agggggtctt gattggtgag gttgttcgcg
     4921 gagaaggagc aatcttggtc gatcaagagg ggaaaagatt tgtcaatgaa atggatacaa
     4981 gggataaagt atctgcagca attacagcat tgcctgaaaa atcagcttat ttgatttttg
     5041 accaaggcgt gcgtgatcgt gccacagcta ttgaatttta tgaccaaaaa ggatatgtca
     5101 caactggaaa gacaatggaa gaattagcag aaaaaatcga tttaccaaaa gaaacactag
     5161 caaaaacagt tgatggatgg aatacggatg ttgcggagaa aaaagatgct caattcaacc
     5221 gtgccacagc catggaacat gacttatcgt ctccgaatta ttatgcgatc aaaatcgcac
     5281 caggaatcca ttacacgatg ggcggtgtga aaatcaatac gaacactgaa gtattagata
     5341 aagaaaacca gccaattagg gggttatatg ctgctggtga agtcacaggt ggcttacatg
     5401 gaaacaaccg gatcggtgga aattcagttg cggagatcat tatttttggg cgacaagcgg
     5461 gcatacaagc agctcgattt gcttcggaaa atgaatgaaa tagaacgtaa ataaaaagag
     5521 gttgtgaaat cagcgttttg agctaatacc gagggtcagc tgattgaaca ctgtttagtg
     5581 aagaggttgt gaaaaagctg ccctgcatca agtaataaga acagccaagt aaaaacagct
     5641 tcttatgttt ttaacttggt tggacttatt accgcagatg caagcttttg aacaccgttt
     5701 attcggaaaa agagcgtggg acaaaagtaa agaacacttt tgtctcacgc tctaaacacg
     5761 tataaacggc ggaagcagaa gaaattcctt cggaaataag ctgaaattca caaaaatttg
     5821 aaaagcaatt ttcgtgaatt tcttcttatt tcttggagtt aaacgcttct gtcccagcct
     5881 cttttttgat cagcatgatt ttattcagtt atcttcaaaa tgatttttcc gatgtttttg
     5941 tttgcttcca tatattcatg cgcttgtttg actgcgctga attggaatgt acggtcaatg
     6001 attggccgaa tcttgccatt ttctagaaaa ggcccagctt tttgcataaa agtttgtgcg
     6061 agctctgctt tatactgatc acttctaggt gtcaataatg taccaagcag ttggacacgt
     6121 ttcccaatca atacaccaag gtctatctca ggcacgatgg tcccacctag cataccaatc
     6181 aagacccaac gtccatcaac ggctatagaa gctaaattct tttcccagta agaagcgccg
     6241 atgaaatcca aaataacatc gactccccga ccttcagtga tttttcgtac ctcttcttga
     6301 aagtcttgtt ttttatagtt gatcaattca tctgcaccaa gttctttaca aaaggcgagt
     6361 ttttcttctg atcctgcagt aacgatgatt ttcgcgtgag aaagctgtct agctaattgg
     6421 atcgctgctg ttcccacacc acttgctcct gcatggatca agacagtttc gccttcttgt
     6481 aattttccaa gccagtaaag tgtttgataa gcagtcaaaa aaacttctga gattccagca
     6541 gcagaaacat agtctagcgt atcagggaga aggattgcac gatcggcagg catcacagca
     6601 tattcggcat aaccacctag attgactaat ccgtatactt ttgtcccagg agtaaaagtg
     6661 gagatatcac ttttattctc aactacctct ccagctactt cgactcccaa aatagggtag
     6721 ggaggtttca aagagactga ttctcttttc ataatatctg ttcgattgac agctgctgta
     6781 tggactttga tcagtaattc gccttgtttt ggtttaggaa caggcacttc aatttgttct
     6841 aatacatcta cagaaccagg atgcttgatt gaaatggcac gcatggatct attcctcctt
     6901 tgcccattct tggaatgctg tattcaactc tttgctacct tcagaaagta ctagagtcgt
     6961 acgagaaata tccgtttctt ccactagagc ggcaagtaca gcagcaactg tagagcgagt
     7021 gatcgttttt gatgccttct cattaggctt agttaattga atggaagtaa cttcttcatc
     7081 gttagtcaat gtgactggtt gaagaatgac aaaatctaag ttagttcgtt tcagccattc
     7141 atctgcataa tgtttagtaa tataataatc tgtcatggac tcaggccatt ttgctggttc
     7201 atctgcataa acagcactga ccatcagata gcgagagaca tgcgcatttt cagctgcgat
     7261 cactgttttg attgcgccat ccaagtctac ttgcagaaga ttctttcctt gagagccggc
     7321 agcaaaaatc aatacatcga tgcctttgaa tgcttcggtc attttttcca cggaccaagt
     7381 taaatcaaaa gagacatacg aaacattctc tttttttact aatgtttggg aagcaacatc
     7441 tctcacccct gcaaaaattt catgggaact tggagctaaa tcttttatca ggtgtcggcc
     7501 aatttgtccg tttgcaccta caacaaaaat tttcatttgg atcatccttt cgacgtcaaa
     7561 tctttccatt caatagtaac accaaaagag aaaaaaatca gagatcggct acgatgacta
     7621 tcagttagta agagaagggt gcttgaagta tcttaacaag acattgcata ctgctgcagt
     7681 cgcaagacct gcgacgattc cttcaggtat accacttgta aaaataaccg ctagaatagc
     7741 tgaataaaca gcatttaaat ttgttccgat gactttggca taatcttgct ggaataaaaa
     7801 gtagatcata ttcatcacta aaatcgtatt ggtcaatgaa ccggaaagtc cagctaagaa
     7861 taaagaaacg gaatctgctt tttgtttcat tagtttgcgc agacctttat aaacgaaata
     7921 aggaaccacc ccaatcaaga tgcgaggaat aaacgcgatc agcaaggctt tccagcttcc
     7981 atgttctgtt ccgatgactg ggataaacgg agaaaagaca aaagacaaag gtgtttggat
     8041 aactgtgcta cggatcatgc tgatcagtcc aaatgtaccg ccaagaaaag cacctagtct
     8101 tggtcctaaa acgatcgaag caatgattac aggaatatgc atggttgttg cattgattgg
     8161 accgataggg ataaaaccta aaggcgtaac agctaataaa atcaaaatag ctaaaaacat
     8221 cgcagttaat gtaaagtttt ttgtattttt cataagtact ccttttttct aagcatttct
     8281 ttcattaaga gtcagcatga cctgttcgat gatcgtctga atatcagcta aggcaccttt
     8341 tccaaaatct ccacaagcta aaagagattc tcttggttca atttcctgat agccgacaga
     8401 tctcaatgtt tccagattac gctgagtgat cgggttttga tacatattcg tgttcatggc
     8461 aggggcaatc aattttggtg ttcccactgg aagcgccatt gcgactgttg aaagaagatc
     8521 gtctgcaatg ccgtttgcta gcttgccgat aatgtttgct gtagcaggcg cgatgagaaa
     8581 caagtcagct tgttttgcta gttcgatatg attgattacc tgcggatttg attcttgcat
     8641 gacgtctgta tggactgcgc gcttcgacag agattgcaag gttaatggcg tgataaaatg
     8701 tgtgctgctt ttagacataa tcacatctac ctgggcacct aatttgacga attgacttgt
     8761 aagatcagcg cttttgtaag cagaaatact tccagtaacg cctagtaaga tctttttcat
     8821 tttgattcct ccagtctaat tttctcagta atcaatgcag caatctcaga tttactttga
     8881 gcttcttcca ctgttccatc tttagataag agatagccgt ggtgtgtctc gccatggatt
     8941 tccgtcaaat catttgcgaa aataaaatca gttttgttat ttatcagact attttttgcg
     9001 actgccagaa gagattcctt tggtacatct actaatagtt tgaaaccaat gatttttgct
     9061 tttggctgcc attcacgtag ataagaaatg atttttggtg ttttcttcaa aacgagcaca
     9121 agatgctcgg tgttagaaga gatctttgaa acagtggtat ctgtctgttc attttccgca
     9181 aaccaattgt ccagttcttc ttgcgttgaa gaagtgggta ggttttttgc cagctgttct
     9241 tctgaaaaac taaaagcagg agtaaaatca ctgactgcca tactgtggat aatcgcatcg
     9301 tagtgttctt ttttcgttag ttcttctaat tgtaaaaata agtccagtgc agattcgatc
     9361 gtataaatcg ttatattgga gtgtcttttc ggtttcagtg cttgtttcgt agtcacgtaa
     9421 tcgattgtgg tatccggatt ggcagctaaa taatcagcta atgcttgccc taatcgtcct
     9481 gtcgaatgat ttgtaatagc acgtacttga tcgatttttt cagtcgttcc tccagctgtg
     9541 attagaatct tcatttatgg tcacctacat ttactagtgt tcttccttgg tgtgttccag
     9601 caagtagttt agatgctgtt tcaggcaatt gatccagagt aatctcttgg acgaccagtt
     9661 catctgcaat ctgcaaatcc gccatctgtt gccataaaga aagacgttga tctattggta
     9721 cattgacaga atcaattcca atcaactgga tgtttcgcag aataaaaggc aagacagtcg
     9781 cgtttagttt gattccccca gcattgccac ataaagctac tgcaccgtta taagagatca
     9841 atggaagaag actgcttagc tgctcgccac ctactgtgtc gatgacatag tcgatttgct
     9901 gttttcctaa agcttttgtt gtctctggca gaaattcatc aggtcgtacg acttgcaaag
     9961 cacctagact ttttagccat gtgacagact cttcttttct ggaaaaggca atgattgact
    10021 ggaatcctag tttatgtaac agggctatcg ctgtactgcc tacaccgcca gaagcaccag
    10081 taacgacaac ttttttatcg gaggtcatac cttgacggat taaagcgttc acacacaaca
    10141 tagcagtaaa ccctgctgta ccaaggatca tcgcttgacg cagcgtcata ttttttggta
    10201 gaggaactaa ccagtctcct ggtacttttt gatattggct ataaccgcct ggatgggtga
    10261 cgccaagccc aaaaccagta gcaagtacaa gatcttcttt tgaaaaacgt ggattgttac
    10321 tttggacgac agttccggat aaatcaatcc ctggagtcat cggatatgtt cgtatcacct
    10381 gaccagactc gctcattgcc aatgcatctt tataattgac atcagaatag gcaattttta
    10441 ccaagacttc attttcagcc aactcagtaa atggcagatc actgattgct gtatggaaaa
    10501 caggttcctt tattacctga aaagatcgaa aagcgttcat tcgtgagaca ctccttttaa
    10561 aattttcttt tatcatacca taaagcctac tcttttattc ttgttcttcc gtaaatttag
    10621 acaaaaatta ggtgaaaaat aaagaatcaa acaactagaa tttattccaa aagataaaga
    10681 aatattcagc aaaaaaaatt ttacaaaggg ttgccttttt caataaattt cgtatactaa
    10741 tacgagtggt agtaaacagg aagtttacta ttagaaaact tcgattcgga ggaaattatg
    10801 gaaattggtg agaagttaag aaatttgcgc atccaaaaga atttgacaca agaagaacta
    10861 ggcgaacgca cagatttgtc aaaagggtat atttcccagt tggaacgaga tttaagttca
    10921 ccatcaatgg aaacattctt ttctattctt gaagtcttag gtgtgactcc agaagaattt
    10981 tttcatcaag aagcagcgaa tctgcaagtg gtttattcaa aagaagatca tacggtttat
    11041 ttcgatgaag aaaacgggta tgaattggaa tggctcgtgg ctgattcgaa tgaaaaagaa
    11101 atggagcctg tcttgctgac ttttgaaggt gcaggagaat ataagacgtt tgaaccttca
    11161 ttatctgaaa cgtttatttt tgtattagaa ggggaattag agttaagctt aggagagacg
    11221 gtctatgtgg caaaagcagg acagtcgatc tattatcaag cgacaaaaca acatcaatta
    11281 aggaatcatc tcaaaaaacg aacaaaagta ttgattgttg caacgcaatc atatttgtaa
    11341 tatagggggt aaaaacgtgg ggaaaccaat catttcattt gatcaagtag tgaaacgcta
    11401 tgatgatgaa acagtattaa aaaaagtaag ttttgagatc gaacaaggaa aattttatac
    11461 actgcttggt ccttccggct gtggtaaaac aacgatccta cgtattatag ctggattcac
    11521 cgaagctaca gaaggggaca tctattttga agggaaacgg ttgaatgatt tgccagctaa
    11581 taagcgacaa gtaaatacag tcttccaaga ttatgcactt tttcctcata tgaatgtttt
    11641 tgataacgtt gcttttggat tgaagatcaa gaaaatgtcc aaatcagata tcgaaaagaa
    11701 ggtaaaagat gctttgcgta tggtccagct tcctggatac gaaaaacggg agattagtga
    11761 aatgtctggt ggtcaaagac agcgtgtagc gattgcacga gcaattgtaa atgaaccgaa
    11821 agtattgcta ttagatgaac cgttatcggc gcttgatttg aaactacgta cagatatgca
    11881 gtatgaactg cgggatctgc aacaacgatt aggaatcacg tttatttttg ttactcatga
    11941 ccaagaagaa gcgttggcaa tgagtgatga gatttttgtc atgaataaag ggaaaatcgt
    12001 ccaaagtggt acacccgtag atatttatga tgagccaatc aatcatttcg ttgctgattt
    12061 tgttggggag agcaatatcg tggacggtgt aatgatcgaa gataatctag ttgagtttgt
    12121 tggtaagcaa tttgaatgtg tcgatggcgg gatgcgtcta aatgaaccag ttgaagttgt
    12181 tttacgccca gaggatttga cgatcacgac accagataaa ggaaaactag tcgtaacggt
    12241 cgatactcag ctgtttcgtg gtgtccatta tgaaatcatc tgttatgatg aacagcaaaa
    12301 tgaatggatg gtccattcaa cgaaaaaagc taaagaagga agcaaagtag gattggcctt
    12361 tgagccagaa gatatccatg tcatgcgttt caacgagtct gaagaagaat tcgatgcacg
    12421 tcttgacagc tacgaagaat aggggggaca agaatgaaaa caatgcgcag gatctattcc
    12481 gtcccttata ttttgtggct cggtttattc gtgatcgcgc ctgtattaat gatcatttat
    12541 caatcttttt ttgatatgaa tgggcaattc acgctgaata attatctatc ttattttacg
    12601 tcggggacat cgctttctat gacgatcaat tctgtatggt atgcattttt gatcacgttt
    12661 ttcacgctga tcatcagtta cccgactgct tattttttaa caaaactgaa gcacaagcaa
    12721 ttatggctga tgctgattat tttgcctaca tgggtgaatc tgctgcttaa agcttacgca
    12781 tttattggga ttttcagtgt gcacggcagc gtgaatcatt tctttgattt tatcgggatc
    12841 gggccgaaac agatattatt cacagacttc agttttctgt tcgtggcaac gtatatcgag
    12901 attccattta tgattatgcc aattttcaat gcattggaag agatgaatcc ttctttgatc
    12961 agtgctagta gagatttagg cgcgaatagc tttgagacct tccgacgagt gatttttccg
    13021 ttatcattaa atggtgtgaa aagtggtgtc caagcagtat ttattccttc tctttcttta
    13081 ttcatgctga ctcgtctgat tggcggaaat cgggtgatca ctttaggaac ggctatcgaa
    13141 cagcatttct tggttacaca aaactggggg atgggttcta caatcggtgt gattttaatc
    13201 attgctatgt tcatcgtgat gctcctgaca ggcgagaaga aaaaaggagg tcgctcataa
    13261 atgaaaaaat ttaaatggtc gtatctttat ttagggatcg tctttttatt cctatatgca
    13321 ccgatcttct atctgatttt ttattccttc aatgaaggag gaacgatgaa cagctttaca
    13381 ggatttactt gggaaaatta tgaagctgtt tttgaagata cacgtttgat cattatcgta
    13441 ttgaatacgt tcatgctggc tttcttatct gcattgatcg ccacgatcat cgggacattt
    13501 ggggctatgg gaatctatta cacgaaaaaa cgacgtgcac ggacagcgtt gttgagcatg
    13561 aataacatct tattagtctc tcctgatgtt attatcggtg ctagtttctt gattttcttt
    13621 acactactag gattcggatt aggttttcag agtgtattgc tttcccatat tgctttcagc
    13681 attccaatcg tcgtcttgat ggtcttgcca aaattgcagg aaatgaacga ttcaatggtc
    13741 gatgcggcta gagaccttgg tgctaataat ttccaagtag tcaaaaatat cattttgcct
    13801 tatctttctc caggaatcat agctggatat tttatggcat ttacctattc tcttgatgat
    13861 tttgcggtta catttttcgt cacaggaaat ggctttacga cgctctcagt agagatctat
    13921 tctcgtgcaa gacaaggaat cagtttagaa atcaatgcgc taagtgcgtt agttttcttg
    13981 ttctccatga tattggtcat tggatactac tttattagta aagaaaaccg tccaaaacgg
    14041 ctgaagaaaa acagaagagt acgcgagggg gtggcacggc tgcgatgaaa aaattacaat
    14101 ctctgttttt aggtattctc atcattattg cggtgctgct gcttggtgtt cgtcaacttg
    14161 aaaaaacaag tggcatgagt ggagcaaagg tacttaccat ctataactgg ggagattata
    14221 tcgatcctag tttgatcacg aaatttgaaa aagaatatgg atacaaagtg aattatgaaa
    14281 catttgattc taatgaagcg atgttcacaa aaatccagca aggtgggaca aactacgaca
    14341 tcgctatacc aagtgaatat atgatccaaa aaatgatcaa agaaaaacta gtacttccat
    14401 tagatcattc gaagatcaaa ggattaaata atattgatcc acgattttta gacttggatt
    14461 ttgatccaga taatcagtat tcgattccat atttttgggg aactttaggg atcgtatata
    14521 acgataaatt ctttgatgca aatcaaatta agcattggga tgatttgtgg aagccggaat
    14581 taaaagacag tttgatgctg attgacggtg cacgagaagt tatggggctt tctttgaata
    14641 gtttaggcta ttctttgaat agtaagaata tggcacagct gacagaagca gcaaataaat
    14701 tgaatcattt aacaccaaat gtcaaagcaa tcgtggcaga tgagatcaaa atgtatatga
    14761 tcaatgaaga agcctccgtg gcagtgacat tttctggcga agctgccgat atgatgtggg
    14821 aaaatgaaca tttacattat gtgatcccac cagaaggatc caatctttgg tttgataata
    14881 tcgttatgcc aaaaaccgtg aaaaataaag aaggtgccta tgatttcatc aactttatgc
    14941 tagaaccgga aaatgcggca caaaatgcag agtatattgg ttattctaca ccaaatgaag
    15001 aagcaaaagc gttattgcca aaagacattt cgtcggacga acaattctat ccatctgatg
    15061 acacgatctc ccatcttgaa gtctacaaag atctaggatc gaaataccta ggcatctata
    15121 atgacctatt cttagaattc aagatgtata ggagataatg gcaaaactca gtaagaatgg
    15181 ggacttatca acgttctaaa gagctaaaaa tcgtcctttt tctatctgag ttttccaatc
    15241 ttctaccaaa agcggatgaa acgccgcttt ttttgtgtta ttttattttt tctaccacgt
    15301 ttttctacca gagaaaagtg gacaaaacca ttgtaaaata gggcccgaga cgggctagta
    15361 aatctaagat tgaaaaagtt acagaaggat aaagtaattg gaaactatgc aaatatactt
    15421 aacccttctg taatctatta ataaaactaa tatatgaatc cagttcaata tttgtagcta
    15481 tgaaaaaaca taaaaatcat attagataaa aactaaattg gtagataaat tattttgtca
    15541 gatatctgag gcaaatattc gactatttgt gtttcaaagt aaaaattgga atacaaatat
    15601 agaatagaca tattgcagcc gatagtttat tatgctttta gacacattaa actggaggaa
    15661 aaaatgaaaa agagcgctaa agatcgagtt tttgatgagc tgatacgact aacagggaat
    15721 atgtcttctg tcactgccga gaaaatttcg aagaatctag gtatctctcg tcagaatgcc
    15781 agccattatt tgacgagatt agtggaagat aaaaaggtcg agaaattacc gggaaagcct
    15841 gttttgtgga agcctttaga tgaatatgcg gttgtagata atacggagca aataaacgaa
    15901 gcctttcatt ctgtagttgg tcatgacgga agtctgagag aggtcattca aaaatgtata
    15961 gccgctgtca aatatccgcc taacggactc agtgtattaa taaatggagc cacgggtgtt
    16021 ggaaaaagtt ttttagccac aaaaattttt gaatacgcta tccatgagca aattattgaa
    16081 aaagatgcac catttgctat cttaaactgt gccgattatg cggacaatcc cgaactgctt
    16141 tcggcaacac tgtttggata caagaagggg gcctttacgg gggctgaaaa ggataccgat
    16201 ggtttattgg caacggccaa caacggctat ctttttctcg atgaggtcca tcgcctatcg
    16261 aaagaaaatc aagaaaagct ctttctattt attgatactg gaaactatcg tccagtcggt
    16321 gaaaatgtaa attggcattc tgctaaggtt cgttttattt tcgccacgac ggaaaaaggt
    16381 gaaaattatt tattagacac ctttgatcgg cgtattcaaa ttagtgttat gttgccaact
    16441 tttgaagatc gccccattcg agaacgatta gagctgattc aattattttt tcaaaatgaa
    16501 gcggatgttt tacaaaaaga tattattgtt tcaagagaag ccttgtcttt aatgttatct
    16561 catcccttta gtgggaatat tggtaagctg aagaatatca ttaaaatcag ttgtgcggat
    16621 gtgtatagtc gaacacaaga agaaccatta acgattggga aaaatgagat cttgattcag
    16681 ttaaatatgc tggaatccga agtagaaagc ttgccgattg ctagtttatt gataaagaaa
    16741 aatcaaaaga taaaaacgga tcgaatcaaa ccgtttgatt atgattcgat tttggaaaaa
    16801 attactcagc tgataaatga aggtaatttc aatgaaaatt tttcttcgat aaagaatgaa
    16861 gtacagcatt tggtgcatca cattgataag gattcttttt tatcaatgag tagaaaattg
    16921 atgattcaga tgtttagaaa ggtctgggta tccgttttag gaaaaacgta cggattgacg
    16981 acgagtggac ctgttgcaga aattattagc agatcctatg tcatttcccc aagctataag
    17041 acagacttaa ccgggataaa tcgtacatta gctgcaaatc tacctcggac gacttactta
    17101 tgtaatcagt tcttggagca tttaccaccg ctctcagaaa aggacgagaa ctttctaaga
    17161 ctgcttattg tcgtgacttt atctgattat gtagatgaat ccatcgagct gaagggcctg
    17221 ttgcttgctc acggagatag tacggctagc agcattcaag cagtagtgaa tcaattatgc
    17281 ggcaattatg tttttgaagc gttggatatg ccagtagaga gtaatgtgtc agagattgtc
    17341 gaatcgacaa ggaatttcgt gaaacggcaa gtgaatacag atagtctagt gctgatcgta
    17401 gatatgggct ctttaaatca aatttacaca cagatcaaga acgatttaaa aggggagtta
    17461 cttcttctga ataatttgac gacttccatt gcacttgata ttggcttgaa gatgacgatg
    17521 aatgcgccat ttaaacagat tgcggaggat gcagcagaca agtattcaat caatgttcaa
    17581 tactttgaag gcttttctca aagtagcaac attatcattt cctgtatgtc gggtttgggg
    17641 atttcggaca aattgaaaga tgtttttcgt catcatttat cggatgaatc catcgaagtt
    17701 ttcacgaagg actacagaga actacgtgaa ttaatcgacc aaaatgatga aacttatttt
    17761 gacaagacaa aattggtcat cacgacttcg gatcttccac gttccttttc aattcctaat
    17821 attaatgttt atgacatctt agacggtgat ggagcagcca atttggagca tattttgagt
    17881 cctgaaatga agccggcaga atttaaccgc ttgattcagg agctagtaaa attcttttcg
    17941 ttggaaggaa ttgcggaccg tttgaacttt ctgaacccaa cgatcgtgat gagtgaagtg
    18001 gaaacagtca tttctaaata tgaaaattac tatcatttca ctttaaatgg ccgtgtaaaa
    18061 ctaaatctct atatgcatac ggcattgatg atggaacgtt tattcttggc tcggacagaa
    18121 aaatctgaag aaccgaatta tgatttgaaa ccagatgaag atgaatttta ttatgtttct
    18181 agaagtattt ttcaatcaat ggagatgaaa tataatttta aagtcaatgc ttatgagctt
    18241 tcgctgctct atgaattatt aggaccgtat attcaaaaat aaagtgtcta aaaagtgtct
    18301 aatctgtttt ttttaggtta gacacttttt ttaatgtgaa ttaacgtgat taaaccaatg
    18361 tttttaaaag ttggcacagg aattgcttat ataaaagtga acagaaagaa aggaattaac
    18421 catatgaaga aaattctaat agcgactcac ggtcacttag cttcaggctt tcttagcagt
    18481 attcaattac tgacggggaa ggttcaagag attacggtga ttaatgctta tgtggatgag
    18541 tgtgattttg aacaggagtt gaatgtattt gtaaaccagg tgaacgagca ggatcagatt
    18601 tttgttttta ccgatttatt tggcggaagt gtcaatcaga agattaccaa aacctttttg
    18661 gagaaagaga ttgctgtaac tattttgtct ggctttaatc tgccaattct gctcgaaata
    18721 gtattggcaa ccaaggaatt aacaaaggag gatattcagg aactggtaaa taaatgccaa
    18781 caggaattaa agatgaccat tcttgatgag gtacatgtag taaatgaaga ggaagatttt
    18841 ttttaggagg aagaaaaatg attaaagcag tgcgaattga tgaacgatta attcatggac
    18901 aagtagcgat gacttggaca aagagtctaa atttaaccgg gttagtagta gcaagcgatg
    18961 aggcggctac caacgatatt caaaagatga cattgaagat ggctgcacca tcgaatgtca
    19021 aagtcattat taaaacagtt gatgacgcga ttcatttgtt aaaagatccg cgggcgaagg
    19081 acatgcgctt gatggtttta gtccctaatg tcaaagatgc ggtaaaagtt gcgaaagctt
    19141 tcccaacgga aatcgaatta atgaacgtgg ggaatgctgg gaaaatgaca ccgccatcgg
    19201 aagataagaa aaccttatca aaggaagtga tgttaacgac gtcagaaatt caagacttaa
    19261 aagaattagt tgaactttat ccagataccg tttttcagcc tacaccggcg atggaaaaac
    19321 gttcagctat ctctattttg agtgattttt agaaaaagga aggagaaaaa ttatgtatga
    19381 tgcatttgta gtcgctttgg ccgtttttat tggagttgct ggacatgaaa tgttcgggat
    19441 gtccatgctg agtcgtccga ttgttgttgc tccgttagca ggagcgttga tgggggattt
    19501 gcagacgggg ttgattgtcg gggcgtcact agaagccatc tttatgggtg tcgtcaatat
    19561 cggaatctct agtacggcgg agccttcttt ggctgctggg ctggctacag cgttcgcaat
    19621 caaaatggga ggaaacgtgg atgcgattat tcccattgtc tttccactag cagtattagg
    19681 attacagtta atgaatatga ttttttcttt tgtatgtgga ccgatggctg ctaaattttt
    19741 caaatttgca aaatctggtg atcaaaaagg aatcatcaat ctgcacttct ttatgtggtt
    19801 tgtccactat gcgctttatg ctcttattcc attctttgcc gttttatttg gagcagatgt
    19861 tgtcaaaagc gtcttggata atattccaga ggtcatcatg aacggattaa cagtcgctgg
    19921 aaatctgctg ccggcagttg ggatggcgat gctgttacgg atgctttgga gtaaaaatat
    19981 tgctgtgtgg tttttctttg gggccgttgt tatggcgtat ctcgagttac cattgattgc
    20041 aattgccgca gttggaacga ttattgcaat tgttatagcc caaagagatc tacaactaaa
    20101 aaatatatct gttcatgcag ttcaaagcga tgctgctgta aatgcaacgc ttgaccaaga
    20161 agaggaggat ttctttcaat gaaattagct gatggaattt ctaaagatga gaaaaaattg
    20221 gttcggaaga tgttttggcg ctcgatgact atgtatgctt cggtgaatcc ggtgacgatg
    20281 ggcggcggtg gtttcgccta ttctatgatg cccttcatta atcatttcta caaaagtgaa
    20341 gaagatcgag ctgcggcgct ggaacgtcat acacagtatt tttcgacgac cattccttgc
    20401 gcgtcctttg tcatggggat tgcggcatcg atggagaagg aaaattctga aaaagctggt
    20461 tttgacgtgg aaagtatcaa cgcgatcaaa acgagtttga tgggaccatt ggctggaatt
    20521 ggcgattcat tgttctgggg agtttggcgt gtcgttaccg cgggactagc gatcaactta
    20581 gccaatgccg gaaatatttt ggcaccaatt atctttttag ttatgttcaa tatacctaat
    20641 tacttgatgc gatactatgg cggcgtttta ggctattcat taggctctaa atatattgaa
    20701 aagctgtatg cgaacgggtt aattgaaatt ctgacaaaag ctgctagtat cttgggtctg
    20761 atcatggtag gtgcaatgac gatcagtatg gtcaaattca ataccgtttt gagcttttca
    20821 atgaagggcg aagaactaat gaatgtccaa gaaatcctcg atagtatttt taaaggaatt
    20881 gtaccgttat tggtaacatt gagctgtttc aaattactag ataaaaaagt cggcgtcatc
    20941 aaaattattt ttggaatggt cgtcttggga attttattgt cattacttgg aatcgcatag
    21001 taggaagctg cagctactag gctgcagttt ttttagcaag gagggaaaag atgactatta
    21061 atgaagtaat ttattcaccc aaacacccat tttttaatgc tgagttaaac gacggaaatg
    21121 tgactacttc aaacgaatac agctactatc ggaatattcc tgatgtaaag ggattgacct
    21181 tcgatgtaag taatcaaaag acattagcaa accttgatgt ttgcgggacg attcaaacgt
    21241 tgacctttta tcgagaaaat ttactaactg aggaaaaacc aggtgtttgg gtcaataaac
    21301 agctctctca aaccaattcg ttatccttaa aggttgaagt aaacgggatt gtctaccatt
    21361 tgtcagaatc ggatcatcgt attgaagtcg atgtgattca agactgtttg cctagatata
    21421 ttcatcatta ttcgacgttt aaggtcattg tagtatcctt tgctcccata ctggctaata
    21481 agcgtttaag tatgcttgtt caacaggttt acattgtgaa tgaaacacac gaaagccttc
    21541 aagtttcagt gaaagatgtg ccttcgtatc aagagaagta ttcggatcag caaaatgtgt
    21601 tgatttctca aaaaggaaat aaggacacga tcgcacaaca ggaagtggca agcttcgcca
    21661 ttgcttttgt ggacccaaat gcttttgaag aagtaatgac ttttcaggaa tctgatatcg
    21721 aaaaatggct gaaggaaaca ttgaactatt ttgctcagct atttgggcag ctgtcaatgc
    21781 caaacgatag agttgtccat ctctatcgtc gtgcacttta tcaaagcttt tctagtttcg
    21841 gtatgaatcg acagggacag gtcgtcggca gcaattgggg cagctatcct gctactaatc
    21901 gaatttggaa taaggatatg tattacgcat cattgccatt caccatgttt gaaccggagt
    21961 tatgtcaaaa aacggttcta tggtttgatc aatatggcgt taagtttcct ggttcaaaat
    22021 ttacaggagg tatcaatcat tctctgagta attcgttatc cagtgcgtta ctggctagtc
    22081 tttattttga acatactggg gatacaaaat tctttgagcg gtgtccgcag gttctactga
    22141 atgcttcaag aattattgag gacatattag ctcaacgtcg gtcaggggaa ccaatgcttt
    22201 ttccatctgt ttggttatca gacgcctttg cacttggaaa gtatcatacc ggcagcaatc
    22261 tttgtctttg gaaggcctgt attggacttg cagaaatttt tgaagcccta gaacaactga
    22321 gtcttagcaa gcgatacaaa aacattgcct gtaaactaaa ggaatcaatt tgtaaacaaa
    22381 tgactatcga tggtcctttt ggtgagcaat ttttggaggg aatcggtgat gaggagaaaa
    22441 caacctattc agtgaagcac tatcaaaaac cgattcttga gcaagggtta atctttttaa
    22501 gtgatgtgat tgtggatgga aaaattaatt tattgatgca tgatggagaa gaatcagaca
    22561 ctacgttgat gcctttttat caatttttag ataataaaga tcatttatat cagaacacca
    22621 tggccttttc tgctagttct ttcaatccaa cctatagcga ggaaatcaaa ggcatcactt
    22681 ggggattaga atccggcgcc acttttcctg gctttatcac tgttttaatg agcgagctgc
    22741 acaaccctca agctttcgta acccgattag aagaactaat ttgtttggca gatttagacg
    22801 gttcgtggtg gtggtggccg tatcgcttag aggctcaaca aggagaagtc gtgcgagact
    22861 ttggctgcgg caaatgcggc tgggcatcgg gtctttttgt cagcctaatg atcagtcaat
    22921 atttcggatt gaaattcaaa aaaggagtat tgcaaattga tcctgttgat aatttaacgt
    22981 tttcttggaa gaatttgaag ttcggtcaag ccttcatttc gattgaatgt acgcaatccg
    23041 agttgagtat ttcaaatttg tcagaaaagc cattgaaaat aagtgatacg aaaaaaattc
    23101 ttcacgtaga aaagggaaaa acgattcaca ttcaaaggag aaaaagatga gtatactaaa
    23161 aaatattacc caatttaaaa aaatccagag tcgagcaatc actcccgaaa atccaacagg
    23221 cgagaaaggt aaagctgcga tgttgccaag cgagctagga ccaagccgca aaggtcgtgg
    23281 cgcaattccg ctgacttctg gtgaagaaac tgtgattgcg gatattactg gaacgggaat
    23341 aattcgtcat atgtggatga cgattcgtga tcgaacagaa tttggcagtt ttgttttacg
    23401 tgatttaatc ttaagaattt attgggatgg gtcggatagc cctgctgttg aaagtccttt
    23461 aggggatttc ttttgtaatg ggtttggaga gcgttgcgag gtgaactcgt tgccgatagt
    23521 ggttaatcct acagggggct ttaattccta tttcgaaatg cctttccaaa catccgctaa
    23581 aattacgatc gagaatttac atccgaagga tatgtcctca tttttttata cgataaatta
    23641 cgctttggtg gacgaattgg aagaaaatag cctatatttt cacgcaaatt ggcatcggga
    23701 acgcattacc aaattacagg aggattataa gttaattgat cgattaaagg gtcaaggcta
    23761 ttacgtgggt acttaccttg cgcttacctg cctagaacgt tattggtggg gcgaaggcga
    23821 gtttaaattc tacattgatg gggatagtga gtatccgacc gtaacctcaa caggttcaga
    23881 agattatttt ggcggggcgt gggcctttca tgagtacgat gagttcggac gtccacatgc
    23941 gaaaaactat tcaacagcct ttttagggta tccttaccaa tcaaatagag atgccacaag
    24001 agatcgtttt gaaacgggaa aattgaatgc cgttcatgcc tttggtgacg acgcaatgcc
    24061 acgacatggt ctttatcgtt ggcatcttca agaccccatc tgttttaccg aagatttatc
    24121 ggtcacttta caacaaatcg gcaacgatga tgttcgctta tttgagcggc aagacgatgt
    24181 tgctagtgtc gcttactggt attcaacaga agcttcagga aatactaaac gtcatttcac
    24241 tgatcgagaa cgcttgccgc gttaatgaag tgtttttcac atattcgaag ggaggaacct
    24301 atgatgatat atggggcaat tgaagctgga gggactaaat ttgtctgtgc agtcggtact
    24361 gaggaattaa cgattttgga aagagtcagt tttcccacaa caactccagt tgaaacaatg
    24421 aagcaggtca ttgatttttt taaacctttt aaggaacaat tggcaggcat cggggtcggc
    24481 tgctttggtc caattgatat tcaatgcaaa tcaacgagtt tcggtcatat cacatcaaca
    24541 ccaaaacttg cttggcaaaa tttcaatttt gtaggaacgc taaagcaata tttcaatatt
    24601 ccgattgaat ggacaacaga tgtcaatgcg gcttgctatg gtgaatatgt tgctggttct
    24661 ggcaaagggt tagcaggtgt tgcatacttc actgtgggaa caggtatcgg aggtggtgcc
    24721 ttgttcaatg ggactttcgt ggaagggttc agtcatccgg aaatggggca tatgttgatc
    24781 aagcgacatc caaaggacaa tttttcagga aactgtccct tccaccaaga ttgtttagag
    24841 gggatggcag caggaccagc gattgaaaaa cggttgggtg taaaaggcca gaatttattg
    24901 gctgacgatt cgttttggca gattgaagcc ttttaccttg cccaatgtgc atacaataca
    24961 acactgatgt tttcgccaga tagaattatt tttggcggtg gtgtaatgaa acaagaacac
    25021 atgaagaaaa aagttcagga taaatttgtt gagcttataa atggatatgt tgaaatacca
    25081 ccaattgata gctacattat tacgcccgaa ttaggtgata atgccggaat aatcggcgga
    25141 ttagcattgg ccagaaaagc ggtaagaaat aagcaaccat aattaatgaa tgtttcattg
    25201 atactcatgt caaaagtatt taaccgagta atcaaatgat caaatgaagt tggataaagc
    25261 gaaaatgaat tcaaataaaa aggctctaag tcaaatcgtg ttgttttcat taaatcactg
    25321 aaaggaaatg cttctgcgtt tccttttttc tttttgttgt gcgctgtata ccttgaggat
    25381 attcactggt ggcgtacact taaatagtaa tatattgtgt tactttatgt ctgtggtaat
    25441 agttatagtt gcttaccaat gtatgttcat ttttcgaaat gttgacttca taatccttgg
    25501 cttaatgttt gaattttttt ggtgatagat tttttcagcc gtataaaata aatcgtaatt
    25561 ctattataga gagttgtgat tataaaaaga tagcaagaaa aaaaaagaaa gtttctatac
    25621 attttaaata ttttattcct atttctattg ctaaaaaagt agaaattcta tatttacctt
    25681 taactctcgc ttctcttgca aatgtagtta gcatttt
//
LOCUS       DADVXV010000035        25106 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.036, whole genome shotgun sequence.
ACCESSION   DADVXV010000035 DADVXV010000000
VERSION     DADVXV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.036"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(612..947)
                     /locus_tag="KB969_001373"
                     /pseudo
     CDS             complement(612..947)
                     /locus_tag="KB969_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1044..1496)
                     /locus_tag="KB969_001374"
     CDS             complement(1044..1496)
                     /locus_tag="KB969_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869368.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(1503..2051)
                     /locus_tag="KB969_001375"
     CDS             complement(1503..2051)
                     /locus_tag="KB969_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBB6869369.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(2096..2428)
                     /locus_tag="KB969_001376"
     CDS             complement(2096..2428)
                     /locus_tag="KB969_001376"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869370.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(2442..2699)
                     /locus_tag="KB969_001377"
     CDS             complement(2442..2699)
                     /locus_tag="KB969_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869371.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(2894..3436)
                     /locus_tag="KB969_001378"
     CDS             complement(2894..3436)
                     /locus_tag="KB969_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869372.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VGQEAQKIDAIKIYYVRSAY"
     gene            complement(3457..4548)
                     /locus_tag="KB969_001379"
     CDS             complement(3457..4548)
                     /locus_tag="KB969_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6869373.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(4556..6766)
                     /locus_tag="KB969_001380"
     CDS             complement(4556..6766)
                     /locus_tag="KB969_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869374.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(6782..9310)
                     /locus_tag="KB969_001381"
     CDS             complement(6782..9310)
                     /locus_tag="KB969_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6869375.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(9362..9772)
                     /locus_tag="KB969_001382"
     CDS             complement(9362..9772)
                     /locus_tag="KB969_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869376.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(9785..10003)
                     /locus_tag="KB969_001383"
     CDS             complement(9785..10003)
                     /locus_tag="KB969_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869377.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(10000..10992)
                     /locus_tag="KB969_001384"
     CDS             complement(10000..10992)
                     /locus_tag="KB969_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6869378.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(11071..11982)
                     /locus_tag="KB969_001385"
     CDS             complement(11071..11982)
                     /locus_tag="KB969_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6869379.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(12001..12345)
                     /locus_tag="KB969_001386"
     CDS             complement(12001..12345)
                     /locus_tag="KB969_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869380.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(12365..12921)
                     /locus_tag="KB969_001387"
                     /pseudo
     CDS             complement(12365..12921)
                     /locus_tag="KB969_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13002..13502)
                     /locus_tag="KB969_001388"
     CDS             complement(13002..13502)
                     /locus_tag="KB969_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869381.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(13503..14048)
                     /locus_tag="KB969_001389"
     CDS             complement(13503..14048)
                     /locus_tag="KB969_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869382.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(14045..15301)
                     /locus_tag="KB969_001390"
     CDS             complement(14045..15301)
                     /locus_tag="KB969_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6869383.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(15661..15972)
                     /locus_tag="KB969_001391"
     CDS             complement(15661..15972)
                     /locus_tag="KB969_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869384.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(15995..17305)
                     /locus_tag="KB969_001392"
     CDS             complement(15995..17305)
                     /locus_tag="KB969_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBB6869385.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(17919..18371)
                     /locus_tag="KB969_001393"
     CDS             complement(17919..18371)
                     /locus_tag="KB969_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869386.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(18373..18738)
                     /locus_tag="KB969_001394"
     CDS             complement(18373..18738)
                     /locus_tag="KB969_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869387.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(18837..23120)
                     /locus_tag="KB969_001395"
     CDS             complement(18837..23120)
                     /locus_tag="KB969_001395"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBB6869388.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(23267..23506)
                     /locus_tag="KB969_001396"
     CDS             complement(23267..23506)
                     /locus_tag="KB969_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869389.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(23596..23868)
                     /locus_tag="KB969_001397"
     CDS             complement(23596..23868)
                     /locus_tag="KB969_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869390.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(23951..24202)
                     /locus_tag="KB969_001398"
     CDS             complement(23951..24202)
                     /locus_tag="KB969_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869391.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
BASE COUNT         7481 a         5368 c         3625 g         8632 t
ORIGIN      
        1 tttacattgg ataactaatt atgactgctg ataacttttg atattaaact agtatctcca
       61 atacaaataa aaaatagata tcttgttcat caaaattagt tcgtggatac ttaccttcat
      121 ttacatcatt cagcggtttc ccattttctt ttattctatt atttcatttt ctaatagact
      181 tggcttcatt tcgcaatact ttttttcaat aggcatcaaa ttggtgttgt ttagatattt
      241 agttgtagtt ttgtgacatg ataagtatgc tcctttttct cttttccact aatacaacga
      301 tcaaagggtg cttttttcaa aaaactagaa aaatcaaaat aagattcgta ttttgattct
      361 atatatcctg tttcaactac atcttatatt tcacaataga ataaatagcc ttttgcatag
      421 ctgcttaact tataagaaat tgcaatttac ttcttcaaag tgaaaacgaa tatgagtaaa
      481 ataaaattat tcttcttaca gataattaaa aatagcgcgt aacaaaaatc ggcattcaat
      541 cacataatta ggattgatgc cgattactta tattctacgt atagttttag tattcttatt
      601 ttttatcacc agtaaccaat tgagaacagc cctaaagcag aatagtcttt tatctcaaaa
      661 cgcttaattt caggcttagg aatatgaata atcttttgag tatattcttt ctcttttaat
      721 cttactgaag aaataccact gcctatcttt tttacaaata tttcatttgg tgtacagact
      781 aataaaacaa tatttgtaat caatccttgc actaaagaat taaaaggaag actatttaaa
      841 acagggtgtg cataactata acatgtgaag tagttatttt gaactttaac ttttaaaaac
      901 tttaaaaata atcttatttg ttcttctaaa caatcatcta tactcatata atcactccac
      961 taattaatct ccccaaaaag acacagcatt aagagatata ccaacacaac agtgcaaata
     1021 actctacatc ttccttcgca accttatttc aataaaccat aaaaattatt ttttaataga
     1081 aactgaaaat taaaactaga aaaagtagtt ttaccgaatg taagagcatc atcaccatca
     1141 atatagaaat acattctttt ccagttacat ttaattttta aacaaaattc tccccaaaaa
     1201 ggaacttttt ctagtgaaaa cttggtaatc tctttgtaat taattcttgt taaagaataa
     1261 ttaaacactt catttttact tgttattttt tcattgacta taactagttc atctggtaaa
     1321 aaaattaacc aacaaacatc gacaaacagt aaatgatata atccatttcc acctccaagc
     1381 atattcaata ctggtgaaca tgccttagaa acacgaatat agttatggtt taaatagata
     1441 ttttctttaa acattgcttg tttaaaagcc atatgctctt gttctaaact tttcataaac
     1501 ttttactcta atgcacagct agcagcagct gctgcaattc ctgctacaat atttacctta
     1561 gctaactctt tagctgcagc ttttcctaat tgtttttctg caatttttaa taataaatcc
     1621 gcagcttttt caaaattaaa agcttttaat gcttcaataa aatctccctg cgtacctata
     1681 gcccaagcca ctcctcctcc aggaagagaa ttaatggcta cacatccagc atatcgtttc
     1741 caatcaactt tctccattct aggaacaata atatgttcat aaaagactct tgctgctctt
     1801 ccttgttcgt tatcttgact gattcgttca cgaatagcac caaaatcctt tatatggtat
     1861 acaccatgtt cgtctaaaaa accaactgta tcaaaataaa aagttaattc atctactaat
     1921 ttattcttta tttctaaatc aactgtattc actttttctg tggcatacac acttgttcca
     1981 gtactaacaa aagtacttaa acctaataag aaaacaccta aaacaccaaa tattttaatt
     2041 attcttttca taatttctcc tccataaaaa ataagttact ttttaaatat cttgtttatg
     2101 aattcattcc ccaaaggcct tttaagattg atacagcagt ccgttcactt cttttagact
     2161 tgtcatacaa gtcttttaaa tgatcccata tcagactagt ttgtctatct agcttcaatc
     2221 cattaaacgc taatgaacgg ttcatttttt ctattacttt agataaagct acagaaattt
     2281 ttataccttc acaacgcgca tcttggattt caataatagt atcatcaatt agtttttgaa
     2341 tttcttgcct atcaacatat tcaatcttag aaagagaatc ttttaaagct actaatgatt
     2401 caacgatttc ttttttctct tcagacattt tcttcctcct tctagtgacc cgtaaagcca
     2461 tgtagagcag agtccattga accagtaatt acactatcta caacgccatt ccaatttact
     2521 ctacattttc catttttcag atttgtcggt ccatacggat agcctttttg acattcaatg
     2581 ttcggattat accagatagg attataccat tcagccgcag aagcagattc agtcgataca
     2641 aacaatccca caccaacaaa tccaatacac atcacactat agccaattag ttttttcatc
     2701 tcgtatccat ctcctaaaaa atagaatagt tcttatagtt attcataaga catatttttt
     2761 ccgtttttgt tttatccttt ctgtcctata acaacttttt tcaagtaaag aatgacatag
     2821 tttttcttaa aaaaacagtc tgtttttttc tatttcttcg gtgtataata aatatgagtg
     2881 ttcatttttt attttaatac gcactccgta cataataaat cttgatcgca tcaatctttt
     2941 gagcttcttg acctactttc aattgaagta atacaaattg agtaacctta ttcattgttt
     3001 cttctccaaa taacaaatat tgatccggat tctctatatc ttgtgtcacc tggtaaagtt
     3061 tcccagttgt tttcatttgt acatgcgggt ctacatcaat actattgtct ttaatacaac
     3121 gatctgtcat atagtccctc acagcttgat tgcgtttata aacatctgtg aaattactcc
     3181 attttctagc aaaatctttt aagaaatttt ttgtcatttc atctatttgc atttgttgcg
     3241 ctgtctcgtc ttctaatgaa ccaatttgac tgttactttc agtactttga agagttccac
     3301 ttgtttcttt tactgcttcg attgtttctt ctgtcgttct caattgtgtt ttttgttttt
     3361 cagaagaaaa ccaatgacaa ccagtaagac ctatcaaaca taaccaacta aatactaaaa
     3421 ttatcccttt tttcacgttt ctagtcactg cctttcttat ttcaccttac gaaccagact
     3481 acgaattttt gtttgattgt acgtgcgttg ataccgagcc ataatccgtc cttgctcggc
     3541 attctgttcc acactagaga aatgttgtcc gccatatgaa acatctgtta taattccggt
     3601 gtgaccatag attccaggag acaatgcacc acctgcttgc caattcacca catctcctgc
     3661 ttgtaaatca cttggttttg ggttcatgat tacttgccaa ccataggttg tccagttata
     3721 atcttcccct attaacatcg caaacatgtg tccagaaccc attaactgtg ggccacctaa
     3781 ttgagataca taccatgccg taccaccata acattcccca ttatttacgg atcgtccaat
     3841 gatccgatcc aaaaccttcg cattgccttt actttttcct gcaataagcg aagttttttt
     3901 tgttggtagg ctattccaat gcttgatcgc aaaagtatca tattccgtta agttatagga
     3961 cgttatgata ctcattgctc ctcgataata cggactccct tcggtaatac ctgctgccgc
     4021 atagcctcca cgacctagaa tcaataaaca acttccagga tctttattgc ccacacattg
     4081 attaaagttg ctttggctcg ccaccataaa gccataatag tcataacaag cttttaagtt
     4141 cggaaacttc atatagaaac caccttcaga accaccaatt ccacgtgcag aaccttgtgg
     4201 gtagggacaa ccaggaaacc aggtaatccc aaaaaagttc gtatcgtttc ttccagattg
     4261 tgactgtcca taagctgatt catagcctaa ttgagaaaga atcacactcg gtaataactg
     4321 atactttaca gctgcaccaa ctgctgcttg cgcatgttca tctgtgattg gaccacgtcc
     4381 tttaatctct gaaaaaatcg gtaatccttc ggtatattcc ccattaaaag cgacagctag
     4441 acctgtagct tctcctccat gctcagaaag ttctcctgaa aaaaagaatg gcaatagaaa
     4501 aaagggaaga ataaagaaaa gaagacaacc tagacaccct ttcttcattt cttcctcatc
     4561 ctttcttcga taatggtttt tggactgttc gtccttttgg taaagtaaaa tcagttcctg
     4621 gttttgcgtc caaaatcggc agtgttttag gatccttttc tattttttcc gattgctctg
     4681 ttggcttatc taaagaagaa aatgcaggtt gtaacgattt tggtgcggaa atcgacggtt
     4741 tactttcaga cgaacgttgc cccggttgtt gcacagaacg atttcctgat agagtggcta
     4801 ccgacgaatt aggaacagag tattggttca ataactgctg cattgctgga taactcccat
     4861 ttttcgcctg atttttcact tggcgaatct gttgtgaaag agaaccagca gctgttaatt
     4921 gtggcacggg tacttttcca gaaggcaacg gaatcgattg accaacaaaa gcgatacctt
     4981 tatttaacaa tggttttctt tgattattcc cttgttgctt actcaattgt gccaatgatt
     5041 gtacctgttg ttttggtctt actgaattca tggacgaatt tggaatcaaa ccatttgaaa
     5101 gaccagaatt ccactctgtt ttcgatttgg tagaagacat ttcaggctct accccatgat
     5161 aacgaacatg acgaccacta taaggcaagg cttgatttga acgcccacct agttcaaagg
     5221 gattaaccac ttgcctccct tttaccgatt cttgtggtgt acgtttttgt tgaaactttt
     5281 gaaatccatg tatcgctgca gaagcgagtg gattcgttgc tcgatacaca ttccctgcta
     5341 atcctgcacc tttgattgcc aaattttgtc cagcagttga tagttgacca ggcagttgtt
     5401 tcatttgaga caaagaatga cttgctatgt ttttcgtgtt gtttatagtt tgatctgcag
     5461 ctcctaaccc tagtttcttt aataaatctt tccgttttac aatgagtaaa attgatagga
     5521 gtgctttgac aaacatattt cctaaaaaac caaaaacagt attcattgga attaaatcgt
     5581 ctactatgtt atagatcaaa aatgccacca aaataatcac actgtaaaaa gatttttgaa
     5641 acatcaagcc caaaaaggac tttaaggtat tcatgagcat ataatcaaat actggaacaa
     5701 aagaagcgag taatgaaaaa ggaatcacaa gtaataaaca caacaccaac atttgaaaga
     5761 taaaacgaat catgccaatc actacaagtg gtaatccaat acttagatta agcaatggca
     5821 ccatagaacc aacgactgct ttataaacag ctttagttgg ttgaatatag acacgataag
     5881 ccttcttttt ccctctatct tctcctgcag cagtggtcac ttttgtctca atatcagata
     5941 attcttcact tgacgcttcc ttggctagaa attcttgtgg ttcaatctct gcttgataca
     6001 attcttctaa atttgttgtc ccataattta acaatatata cggatcaaca acagccgctt
     6061 tataataaag ttggcgcact ttttgaatgg cttccttttg tgtcgttggc actaaaacac
     6121 cattgacatc ttttgtcgcc aattcatcta gactatttgt agcagaaaaa ataaagcctt
     6181 ctacctccac ggacaaatca tttaaccctt tggtaaaagc ttctccttta ctaggtacgt
     6241 tactaccata gccaaaccaa accattgaaa aaatgacaac gaagagaaat cgaataaaca
     6301 ccatttttgc gtaatgtttc cctctaaata tacgaagagt aaatagatat aacacataca
     6361 agacgacaat ccccgcacca ataggatcgt atatttttga ataaatagta tccgaaaaag
     6421 tgaaaaactg gtgaattaac tcgttcattg cagctccttc atagagcttc tcaatgacaa
     6481 aatcaaggcc ttgccaaatc aatttactta aactaaagaa catattcgtc atcattttta
     6541 gaaaatctgt gccatttgcc ccaaataaca ttttgcctaa tgaaaattca ctatcagata
     6601 aataagaaga aaaggtatca atatgaaatt tcccaatctc atagatcgat tgatccacct
     6661 gcttttctgc cgcatacacc aatccaccaa caaaaagcag tccgaatcca atcgttaaaa
     6721 aaaacaaaac gcaccatttc ttttccttat gctttatata agccattgtt tcacctcatt
     6781 tctattgcat gattaacgta tcctgttctt ctacttgaga gtgacttgtt ttttccgttg
     6841 tttgtaatgc agcggtcatt tcttcaaaca aactgtgtac attgagtttt cctacacgtc
     6901 catagggatc taacatccaa cactgtcctt taatcatgtg gctcatttca gctaagttcg
     6961 cttcatttac ttccaaacgt aaatgattca aaatcttttc tcgctcactg tcttcatcaa
     7021 aagcaaagac gacaccaaaa ttcccttttt ctttatctga acctaagtca ccaataaatt
     7081 gtgtatctaa cactaattga ttcatctggg aacgccccac acgtgccatt gctgcaataa
     7141 tactacgtcc tgcgttcgaa ttattaaata cccatgcttc tgtaaaataa atcgctgttt
     7201 tcttactact atctcgtttt ccaaacattt cacaaaaacg acctaaacta atcatcaaac
     7261 acaaagactt tcgatccgca tctgtatata gttctggtcg gacattgtca tttggtaatt
     7321 tcaaatcttg gatctctaaa atcgttgttt tggcattaaa gtctaatccc gggttttctc
     7381 cataagaaaa tcctaaacgt aaaatcgaat cttctaccgt caagcgtaaa aactcaccat
     7441 attctcgaac ctctttttgt tccatttgtt ctaaatagtc gaccacatgc atcaagccaa
     7501 cttgttgtcc ggcttctttt tgaactaaaa cttcttggat tccctttaat accgcccctt
     7561 ttaaaaggtg attggtacct aacggactta actcatcaat catatcctgg gctacttgtt
     7621 tcgcatctac tcgggataaa caaacaattg gatctaatac accataatta cggggatttg
     7681 tagcatctaa cgtgacataa ctcatttttt gcaaatgttc tacaaacaaa gggtaatgtt
     7741 tctgataata cgggtcttga atgagtttcg taaaccattt gcgcttttct cctttgggat
     7801 ccacaaataa actttgtaca ttcataaacg aactatacaa aaagagcaag ccaactaaaa
     7861 aggtcttccc tttaccggtt tttccagtta ctgctacatg aggcgcatca aacaacgcac
     7921 ctttgattcc ttccgcaatg gctagaagat tcaaaaagac aaaacgattt gacgcataaa
     7981 ttaattcttc taatggtgtt ttttctcctc gagaaccacc atcccctaat gtatcttgcc
     8041 gaccaatata ccagccggat tccataccta attctgatac tgctgaaaac aaccattcgc
     8101 caactgcttc tacagttgtt cggtgcttcc aatgtaactg ccgtcccaat ggttgcccta
     8161 ataaacattt atagaacaat tctcgttgat cattttttgc acggtggata tggataatcg
     8221 tatgaagttg ttgaataacc gttgcactat tttgacgaac ttcttcaacc gtttgaccgt
     8281 atacaataaa acatgcgatc caatcgacga caggttgccc attatctact cgttgcttta
     8341 aatgttttac taatcctcga acagttaata agcgttcact aggttcttca tcattttgaa
     8401 ccaattcctt atgctctgtt ttgaaccgtt ccgatagcca attcagtttt aaaccaatac
     8461 ctccctgtcc tttcaagcgt ggatagtgaa ttttcattcg caattctgct gggaaagaaa
     8521 gatcctgagc aaattgaaat agatcacaat ttctcatatt ttcaggtgtt tccccaatag
     8581 gcaacaatgc taaataacta ctccctaact catcttctaa ttgaagaagg cctttatgtt
     8641 ccttcggtat acgtacatac gttccttgat tgtctttcag tacttcccaa ttattttgtt
     8701 cttctacttt gtgagccatt cctcgaatat attgcagacg attgagatac aacagctctt
     8761 tttttactaa gggacgaata gaaaagctat aaagtaattg tgtcacttct tttacataag
     8821 gatcactttc agaaaacaaa gtttccaaat catctacttc taatccaaat aagcgtgcta
     8881 aacttcctgc taaatctaac cagattagat ttattacatc atgaaaactc tccaccgttg
     8941 ctttttcttt gactttgatt cctaaaataa atgaaggacg atagacttga ccttctcgtt
     9001 ccaacaatgt cactgtttct tttgcataat acgcaccaat tgcttgacta tcgggagaaa
     9061 atccctttcc taatgtgtca aacttcgtcc gtaaattcat tgttcgtgga tacatcacca
     9121 actccacatc ttcataatct gctaaaagca acagtaaacg agccatcatt tcttttattt
     9181 cctgtgtctt ttttggtgtg ttttttgaaa ttgttcgtgg aaaaacatga tagtaggccc
     9241 agatacaatc ctctccattt aacaaacaat ttttcttgaa tgcttttact ggttctttta
     9301 caagcaccaa tgaatttcac ctcccaataa aaaaggaaca accagttgat tgtccctttt
     9361 tctaatcctc taaataaaca tacttattca caaaaagtaa ttcttccaat gcattgtttg
     9421 ataccttgtc ccagttataa tacacacaat caccattcat catacgaatc atataacaaa
     9481 accaatccca taaataaaaa tgcacttttt ttccatcagg ttttagtttt gccagtgcta
     9541 acacacataa ataggggagt cctatataaa aaacaactcc tgctggtgga aaaaaagaaa
     9601 tgacccaacc aataaatgaa cgtaaaaata aatattcaaa gattacgacc aacaaaaaag
     9661 ttgctgcatt gactaatgca actggaaatg gaagacgcca attgcttgta atctgttgta
     9721 cgcgataagg ttccgcataa acaatcgaat aatcataagg ttcccaatcc acttcactat
     9781 cctcctaatc cataaataat ttttcaatga ttttaccaaa cgcatcaaat acacgtgttg
     9841 gatcatttaa gaagaaataa actgcggcac ctgctgcgat agatattaat gcatttccta
     9901 cttttgattt cataaaattt cgcaatccca gataaacaac caccattatt aaaaaatagc
     9961 caccttgcgt taatataaaa tctacaattc ccttcagtgt catttccgtt cttctccttt
    10021 cctatccaac caattatgtg ttaatttttc aacataatac tgatttgttt ttttcgtaat
    10081 gacaatcgtc atttgttctt tttgtaaaag tgacgtatca ccatctcgaa agacgaccgt
    10141 tgcttttaca ataaaaggtt ttttcgtttc tttataacgc aatactttca tctctacttg
    10201 atcaacttta gctgtttgat tgagtccttc aggttctttc atcatgtatg acatatcttt
    10261 tgcattgttt ttcgcatact tatctaagaa atcttccaca aatccttcaa catctttcgc
    10321 ttccgacgca tcaaccgttt cgtataatgt gtcatcataa gtaatcattc gttgtttttc
    10381 tgtattcttt ggtagtgccg taaaataagg ataagcaata atacgacagc ccttgtttga
    10441 aatagaaaag ggaagattga gtacttgtgt gattgtcaca cttgtttctt tcttactctc
    10501 tggattcatc gagcgaatat cataagttac tttataacta gcagttggaa tggtttcaat
    10561 ttcttttaat ccaataaacg aagcagcagt taattttcga acacctgaaa cacttcctgg
    10621 ttcttgaata aagttttgtg cataaaactc tttttttaat gtttcttgac gttgttgttc
    10681 ttgttcatga ttatcgaatg tattcatata caaagcaaca aaacgattca taaaggattc
    10741 aatttcaggt gtgtacgtta attctgaccg actttgtact tctttctttt gtaattgttg
    10801 gatttcatct ttcaaaaacg acacttgaac cttcgttttc atggattgaa aaaatgccaa
    10861 gccccctgaa aaacaaagaa ataaaaccaa acaccaaatc catttcactg ctttttttga
    10921 atggattttc ttttgcttcg gtactttctc tgtataaact ttttctttcc gccgtagttg
    10981 tcgttttttc ataagctact ccttctagta tgtttttact agtacgtacg attgacaacg
    11041 ataagcttgt ttttctgaaa aatagtccat tcaattaccc tcattttcta ttccttttct
    11101 ctttctttta tatccaacaa atccagcaat acttgtcaac actcctccta gaacagaaag
    11161 tgcaacatgt atttcttcac cagtctttgg taagactttt gtttttccat ctgctgtttt
    11221 gatttcaata ttgccacttg gaagtttctt tacaggaatc gacaaatcct ttaccaaatt
    11281 cccttcacta tcttggatta atggaatacc atcttttaca ccaacaattg tttgatcacc
    11341 tgctactttt aatggggtgg ttggtgttgg aatatgggtc aattcctcta cattactagt
    11401 gacaatcggt acactcattc cttgagaagt attcgtcgta atttcaccgc ttggggttac
    11461 cgatactgtg acttcttttg ctggaacaat aggtttattt tcttttggaa ttgcttctga
    11521 tttttcaaca ggttgtttcg gttcttcttt ttgttcttca ctggtagacg acatcgttgg
    11581 ctgttccgta cttgacgaat cagtattctt ttcagaagaa ctggttgttc ctgattgttc
    11641 cggagttgtg actatacttg aatccgttgt tgttgaacta tgcacacctt cttcttcgat
    11701 cgaatcagtc ggtaaagttg attcaggaaa ctctggttct ggtgtcactg gctctttttc
    11761 aggtttctct gactgcaatt gttcaggttc tgctggtttt tccgttgttc ctccatttag
    11821 ctctgtctca acatctggta atccttcccc tggcaatgtt tctacaattt ctgacttagg
    11881 tgtttctaca gtttcatctg cataaaccaa tgaactccct aattgaaacg aaaataatga
    11941 aattcctagt gttgttacga ctgctaatgt tgtttttttc atgattattc ctccaatttt
    12001 ttatgcaatt cgtgttttgt tcatagacgc cgcactaata ttatctgaac gataaaagaa
    12061 ctcccgtccg ttttcttcta acccaacata tggattattt ttgaataatt gaatcaatag
    12121 ttcactggtg ttgtattttg gatagtttgc aaaaaaataa tactgtgctt gtcgcccatc
    12181 cgaaaattca acaagtaatt cataacgata ccgcttcaat ccttttcgtt gttttaaagg
    12241 atctctatac caacttgtcc atcgttccat tcgtggatag agatagacac gatacacata
    12301 gaacaatgcc ataccacata ccaccaaaaa taataatcgc cacataaaaa ttcccccttt
    12361 tcttctacct ttcttgaatc atcgaacatt cataccctct atagagattt gaaaaatcca
    12421 tcatcaattg ttcatataaa cgttgttgca aatagcgatt gtttcgaata cataattctt
    12481 catagccatc aatcacttga tcttcttttt catagcatct tgtagctcta tgacgctcag
    12541 cttgcaagac ataaccaaac tctgcaccat atcgttctac tgttaataac tgttgactac
    12601 gcaataatgc aatataacaa tcacaaaaat gttcaaccga catttgattt ttctcacgtt
    12661 tgtgaaatag gtattcttta gaaagcacat tattcgttaa acaatctgat aaatagcgat
    12721 aatctggcgg tcggttattt tcatctgtga atttttccca taataaactg atttttattc
    12781 gttcagcggc tagatagtct tgttcgcgtg gataaaattc atcaatcgca caaagttttt
    12841 tatcacctga ataaacaaat ccatataatg cgaaacgaac tcttcctttt caattggctc
    12901 tcctaaaaat tccagtgaca taccatcttc tccttcctaa aaaaaataaa aaagcagaaa
    12961 ccgatttggc ttctactttt ctttcctttt atagctcttt tttacggaag aatccgcaaa
    13021 tgacattttt tcaaaaaatc aatcggcaca agttcacgaa aacttggagc aattttggat
    13081 agaatcactt ccccatcttg taaaatacaa tcataaaaat catcagttac ttgatactta
    13141 cgcttcttac aataattgat aaaatagtag cgatcatttt ctatttccat tcgttgttct
    13201 actaagcgca tacgaacatc atcatagaaa taagccacaa atcgcccttc aagttcatgt
    13261 ttttcaatgg gatactcttc tggtaacaat ctattttttc gtcgtttata cattgctgga
    13321 taccttagaa gaagttcatc taaacgtctg tcagtatatg gtaactgacg aatcaacgat
    13381 tctaatcgtt ctttatacag atagaataat tggcgcaagc aatagtgtac cgcctctgga
    13441 ttttctaata ctgttggatc acgtgaccaa tacgcaccaa cataaatcat aatttttttc
    13501 atttagacaa tcacaccagc aatactaatg accgatccac aataggtaga acaagtggca
    13561 tagcgaccaa tttcctctaa ttctatctca atctcttcta aagaaagata tgtctgttct
    13621 tctgttggct ggcgactcat ttcccaagtg acagtcacca atgaaatttc ttccataaga
    13681 ggtttttcgc tgctaagtgc tgccacacag ttttcatata tcttcatttt atcgcagcct
    13741 tttttaaccg ctaaaatcgc aggtattggc aatgaaaatc gataaaagcg aatgaattct
    13801 agccttcctt tccttcggct aaattccaac tcttcgagtt cttgttcgta tcccttacga
    13861 acttctaata agcgtgcaat ttcttgccag ttctcttttt cctgataacg tccagctttt
    13921 accgcttgtt caatataagg aactcgaaaa cgaaaataag acaaatcaac catcttttca
    13981 tttaatgctt cgattgcagc ctttaaatcc aacaggcgca gccattctgt tgtcgtatat
    14041 gcattcatgc aattttccct cctgacgttc ccatccattc tagatagttt tgttgctcgt
    14101 catttagttc ggcattatca atcccttctt gtacaaagtc tcttcctaaa atacgatctg
    14161 cttcttgtaa caactttaat gtcggagcta cttgtttcaa aaaccagcgt tctgaacgat
    14221 ctaatgagaa tttttctggc tttactgtaa aatccaattc ttccatcgaa cgaaataatt
    14281 ttgcccatcg tttatcaaca atccgtgcat cactttccag tctatcccaa acaataagtt
    14341 ttgcattaat taaaccaacg ccaatctctc ctaaacgttt cggtgaatca cctaaaataa
    14401 atgcttctac tgcttgtgtt gctttctcat tggctaaccg taactcatat cgattataaa
    14461 taccatattt cgttaatgct tctaattctg aaattttttc tcggttcgca atttcaaaac
    14521 gtttctcata aaaattaaaa aagagaggac tctttcgcga tccaaaatac aaagataatc
    14581 cttcacttcg aaaatagcca tcatctaaaa aacaaccgcc aatattctgg aatctcttaa
    14641 agtccatttc taataaacct gctttttgtt tttctagtaa ttcaaagaga tcgaaatgtt
    14701 cttccgtttc caatccccaa agttcatcta acgcaatatc gaatcggcta cattgcacac
    14761 gtgtataacc agcttccaac tttccttgat ttttccaaat ggaatatagc catgttcgcc
    14821 aatctgtttg ttgttcacgc atgacttcct catattcccg gcaaccttgt cctgaaaatt
    14881 gcacaagtac attttctgtt acagttcgtt ttgaatgcca gaacacccag atattcccac
    14941 gaacagaaag acagtcaaaa agatacaagc ccgttggacg tgtttcaaat tctgtcagat
    15001 ccattcgtaa tacacgttga atcactgttt tgtagtctgt cccaaaaaag gaaagacgca
    15061 aataatcaat cattgctcga agatctattc cgcttttcat atacaatcga aagcgttcct
    15121 tgattcgttg ttcaaaatcc tctgggattt ttcttttccc ttgttccatc tttctaatgt
    15181 aatcttttga gcagcccatc aattgcgcaa atcttgcttg tgatagcggc tttttatctc
    15241 cacttatatt atgaattgca cttaacttct ttctgtagct ttttagctca atcggtgtca
    15301 ttttctcgct ccttttataa aataacaaaa tcgatttttt taacccttta gaaacaccga
    15361 tatatcaact agtccccctc gttttttggg aaaagtagta caactgctga ccttagataa
    15421 tcacttgata caaaagggtt tataaaactt ttttctatgt gttatgttat ttctgccccc
    15481 catattatat atcggggggc tttacacaaa gaggccgtgc gcaagcgcac gacctctttg
    15541 tgagctgcac acgctgctag cgagtgcgca ttataggccc atgcttcgca gccttaatgc
    15601 gcaccgccag gcagagtgcg gctaccagac tacgtctaga gccctcccga tagataataa
    15661 ctacaaaatt aaatgatcta attttgttat ttcactatat ttttcaggag aaaaaacgcg
    15721 ataaattgac aaagttaaat cctcttctaa atctactcga taatgataca atcgagtcaa
    15781 tcgttctata tcttttttcg ttagcaatac ttgattaata acttttcctg taaaaacacg
    15841 ttctttgcgc aaaaagcggt aatcagttac ttgttcaata cgattcaacc aatcataaaa
    15901 cgttctggaa gaaagagaag gattaatcat tcgtattgct gtagctactc tataataaca
    15961 actctctgcc atttaacttc acctccttag ttgattacaa aatatgcgca tcagaaaaac
    16021 ttgttccttt tggatctttt gctaaataca tttggcgctc tagttgttct tgtaacaact
    16081 gattatcatc tcccatcgtt tgatcttgac tatcctcttt tactgtaaaa tcatagacaa
    16141 tcatttcagt aaatttctca aattctttga taaagtgata atctttgtaa acaaatggcg
    16201 caaaaaactc tacaggtaca tcaaatcctg gaaaagcata tccacgacca ggttgatctt
    16261 tgttgtaaaa tggcttattt ttaaaatctt ctccaaaagt cattaaataa ccaatgggag
    16321 acaatcgacc aacagaaata cggaatgtta aattatcccg aacaccactt ggaaaatatt
    16381 ctgcatctgg tcgttgcatt gctaaaataa tgtacatccc tgcttgacga ccctttaata
    16441 ctaatggctg aatcaattta tcgactctat ttctcgcttc catatccaac gaaccataaa
    16501 aagctgccca ttcatcaaaa aagataaaat gcggtggtaa cccataataa gcataatttt
    16561 tccctggttc atatttagga tctttcatgg ttttcatata ggcataccgt tgattcattt
    16621 cttttaatgc atttcgtaaa caaataatca tttcttcatt tattttgtaa aacacatgtc
    16681 ctttgaatac atcgacgtca cctaatgctg ctaaatctgc cgcttttcca tcgcaaatat
    16741 ctactgtccc aacacttaaa caagcttgaa ttaaagaata caataaatag gttttcccac
    16801 caccgattgc accagcaatc aacatatttg gtgattgatc atatacccaa tccaaagttt
    16861 tcattaaatg aatacgtcca ttttctgcta tacattgatc aataggaatc cgaccagaat
    16921 ctgaaaggaa tacataattg attcgggctt tttctcgttc ttcacgaatt aaatcacgca
    16981 aaaatacttc agataacaaa tgacccattt ttaaaaatcg ttcgtgaaaa cgcccaccat
    17041 ctaaaggaaa agaaaccact aattcttgtt tcttttgata aaaataaact tttggtaatc
    17101 tcattttttc ccttgtttgt ttctcactaa cttgtttctt tgtataaaca aaccgattgt
    17161 caattaacat tcgaacaagt aactgacgcc aataaacaga ggcaaaatat ccttctttta
    17221 gtcgcgacca atgcatcaac cctaaaatta acccactaac cagcaacaaa tacaacacaa
    17281 tacttattcc aggaataaga tacatttgcc aattcgaaaa cgtacttaaa cgtggataaa
    17341 atactttcca actaaaccaa cctaacagaa tcaaaaatgg aaacaaaaag aaaccataat
    17401 agcaaaacca taaataacga ttgaaatagc gaattcgccg accacgatac ttgaaaaaat
    17461 gagctttcaa ttgtcacatt cctcctttct gtttttactt ttcctgtgct aaaaactttt
    17521 gacaaaaagc aactaataca ggaatatcac atttagtaaa aaaacataat cgaaaaagat
    17581 ttaatcgatt tttataaggg tgtgcacaca tattacatat tcgtactata cgaatccaaa
    17641 tcacttcctg atgatcttgt ttccactggt acggtaatga aaaacgaaca agatcacgta
    17701 aaaacataca ctgcccaata accgcacaaa tatatgcatt tgtttgtaca aaaatcgttg
    17761 gattgtctcc aaaatactca atcaattgtt ggatattttg ataacaagca caatctctca
    17821 aagtatttga ttggttttat ctgaattcaa aatctcccct tccttctatc ttagataaaa
    17881 agaataggaa gactccttcc tattctttca aaaaaacctt attttttctc tttttcctta
    17941 gaatcaacac ttggttgttt ttgatctaaa cctttttctt gtgattgttt catattagga
    18001 ttatttgttg gagcttctac tttctctaat cctttcgcat aaatcactaa atctgaatat
    18061 tcacgattgc catcttgtgc tggaatatat accacatgat attctggatc aattaatttc
    18121 acaggatcac gtcgtttaaa accagtcaaa tctacatctg ctggaaattt aactcgtcgt
    18181 gcaatctttg gttcatctgg atttccaaaa actaattgtg ctcgctgtga tcgaatttct
    18241 cccgtataat cgcctgtttc attatcaaat acacgatcag actcttctaa tgcgccaaag
    18301 cgtacggctc ctaaacaagt ttcatctaat gcttctgtaa tgtcataatt atttggaaat
    18361 tttaatccca tcttacaaaa cctccccaat ttttacacca gttaaaaaga caccaacatc
    18421 ttgatagcca gttgttcgac gctctgtttg tcccatatca tttgtttcac gactattcac
    18481 tcgttcttta cgaaaaacaa aataagcttc ttcaaatgaa atacgcacct ctttttctgg
    18541 taatcgtaat cttttatcct cttcagctgt gagataaaca aaaaaagcag gctgttcttc
    18601 tcgcgaacac tctgcttgta attgaacata tcgcccagac acaccattaa tttcctttgg
    18661 tggattaggt tcccgtgaac ccaataaaaa tacttgacct aaaaactctt tcttcatacg
    18721 caatgctttt tctgccataa agtttttcct cctcttaaaa accaaaataa attctaaata
    18781 tttctacatt acaatcaaac aagcggttaa aaatcctaac cgcttgttcc tcatgactaa
    18841 tctttggctt tacgtacttt ataaagtgtt atacctaaag caatgactaa tactactaat
    18901 ccaagaacca taagtatact acttgtttgt tcacctgttt ttggcaacat tggtacaaca
    18961 gtagctggtt taacccgttg ttctggtttc actggttgcg gtggttttgg cgcttccaca
    19021 atttgaaccg tttgatcttt gtttgttaga tctacattgt gtttcgccac ttcttcaaac
    19081 gtttctttct catcttccgt tttcgcttgg agccattccg caaaactcaa gccttttcct
    19141 gcaagattgc gaccgtccac taagaattca aataagaatt ccatcatttc tttatcggcc
    19201 gcaaagactt tttccgcatg agtgccttca aatggtgtgc cgtctggtgt taagtagcct
    19261 tgaacaatta agcgatagat ttgaccaatc gcaagaccgt ctactttgac ccattcaagc
    19321 acagtttgat ttggcaaggc caagatctct tttccgccat ttttattcgt cgctttcgtc
    19381 gtaatggttg gattactgat tttgatggtt tggtcattgt cggtaatatc tgcgtgagaa
    19441 gccaataata cgccttctct aaacagatct tcaaagacca cgacttcttt gcctcgcaac
    19501 gcacgtgcgt ctagaataaa gtctagattg actgtaccat ccgttgtttc tgccacaaac
    19561 gttaaggtac ttgtgacttc ttttccatct actagcactg gtttttccgt tactttgtcc
    19621 attagaacac cgttgactgt gtatgttttt ccaacgacca aatcgtggta tttcacagcg
    19681 tctgtaatgg tgactttcgt taatggatta acctctttca agccagtggg tttatgtgta
    19741 gccgttgtac gtacacttgg gttagttact cgtaccgttt gccctttgtc gttgatgtct
    19801 ttatggtttg ctagttcttc atcatttcta aaaagacttt caaacacgac gatttcacga
    19861 ccatttatac ctgtcaaatc aaaggtaaat ggtacgatca ccgtttcatt ttctgctttg
    19921 gcaataaagc caacactcgt ttctaccgta tttccatgca caagcaaggg ttcaccggtt
    19981 gctttatcca ttaagatccc tttgaccaag tatgcttttc ctggaagaat ctcggtaatt
    20041 tcaacggtat cgtttaaggt aaacaatcct gttgggtctg cgactgtcaa tccgtcttca
    20101 aagacagccg tggtatgaac ggttggatta ttcactttca cactttgggc ttcatcgttg
    20161 atatccgcat gtgctgcaac ttcaatgcca tcacggaaaa gtttttcaaa aacaacgatc
    20221 gtttgacctt tcagaacact agcattaacc acaaattcaa ggtcttttgt gccattgact
    20281 ttgtctgcaa taaaggccaa ggtacttgtg atttctttgc catcttgtaa aattggcgca
    20341 ttcgttgcct tgttcatcaa tactcctgaa atggtgtatt cttttccgac aaacaagttg
    20401 gtataagaaa cactgtcttt aatgacgatc gtttctaatg gatcaaccac tttttcacca
    20461 tcggctttat ttgacgcttg tgtttctagt tttggtggaa tcaagtaatt acgtacagaa
    20521 accactaacg tttccccatc atctggcgca ttttgtttga atgcaaccgt gaatgcttgt
    20581 ttatctgtat ttggttggaa actttctaat ggggcatttt ccaagaagta atagtcatcg
    20641 gcaactagac ctttcactaa aatttccccg ttttgatcag tggtatattc accaattgct
    20701 tgatttttac cgttatacaa ggtaaagttc acacctgcga gcggcgtttt cttcttgttc
    20761 cattcttcat acttgaataa ttttacactt ttccgtgctt gacggttcgc aaaatggatc
    20821 actttgatcg gttctgtatc attggtaatc gagaacacta atgggttttg attcaaaacg
    20881 taatttacgg gggctttgat ttcttccaaa cgatagcgat cttttccata agtaagtgta
    20941 ccgttagtta ggaaaaagcc tttttcattg gttttaaaga tatccgttgt ttctgtatca
    21001 tttggaatct ccattgtgac ataacgattg gctaaagtat caaaaatctt gaattctgta
    21061 ttagcaagtg gaatcacttt tcctgtttct tgatccactt tcaccacttt aagacgttgt
    21121 tcaattactt tatcttctaa aacataatgg aaagtttgcc cattttcaga aattgtgact
    21181 tcaagtggtt caaatagttt atacccttct tttcctttgg tttcagaaag aatgtacgta
    21241 tcaaagacaa cggtattttt accaaaagta gcataaccat cattgtctgt cacaacggtt
    21301 ttcaccactt tgccagttgt ttttgacgtc aaagtgattt caatgccagc taattttggt
    21361 ttgttatctg gattcgttga atcgactaaa tctttattag caactttcac taaatcaatg
    21421 gttcctttga tcacttgatc ttttgcggtc gcattgacag tttttccagg ttcaacaaca
    21481 atttcaattg cttcatcaga aagcacataa ccttttggcg ctttgatttc ttttaaaaca
    21541 tatttgccag gatcaagatc tttaatttct gcctgtactt tgccgttaat ttttttcaag
    21601 gtaatttctt taatcttttt cccatctgct tgatacaaac catagaccgc attttctaaa
    21661 gaagctgcac cttgtgcttt cacaccagtt tccgcatctt ctttaaacac acgaatgttt
    21721 ccttgtttta gaatttgtaa attaataaca gacgcattag gttctgttgg atgtaacaca
    21781 ccaattgttt gagctcctgg acgacgatag gctaatggcg caccttgaac tttaatttta
    21841 ttcaattgaa tttttgcttt atccggtgcc tcttttgtga ctgtaatcca tacttcattg
    21901 ccgtgaatag atacattgac accttttggt ttttgaatgt ctttcacata tttcaaaaaa
    21961 tcatttttat tctttacttt caacgtttcg ccaattttta ccgtatgtgt ttgattatta
    22021 aaagttgctt tttcaccaaa gttattaatc aaacgttgaa tttctgcttt tcgacgatca
    22081 taatcaacac ggatattttt gattgggatt tttgtgccca aagcttccca aatcataaat
    22141 tgtgccgcaa tgtattgttc atcggatttg tctttatttg tgacatatcc taaataagag
    22201 atcaagcttg tttttttccg tacatttgaa tttttcaaat agtttttcaa agcagtagct
    22261 gtataaactt gaccttctgc ggctgagaca ccaggctcaa tacaaaacgc cacttgtcca
    22321 ttaatctcaa aacgaaccat ataatttaaa gtgaagttta gattgttcgg actagaagta
    22381 acaccaatat tttcgcccca atcaattttc cgaccaccta aaacagctgc attggttgca
    22441 cggcgaacac gaaccgaacg attggttggt actgttacta acagtgtagg tgtacctgtt
    22501 tttggaatgt tctgctcttt tttcttttga ttttcaatac tagccgtaga ttctttgttt
    22561 ggtttcgttg gttgattttg actagctgcg gttgaagaga ttgttttttc aacgttttcc
    22621 tcattttttc cttctttgtc agcagtagcc gctggttgtt ccactgtttc ttctattcgt
    22681 ttcttttctt ccgcttgttt ctcagaagac tctggctgca cagaaggcgt tgcttcggca
    22741 gctttttctc cttctagagt ggacgtttct gaagcagggg ttgtaattga ggcagtttct
    22801 tcaactggtt gtgaagtacc aggactattc cctgggtgtt gtgtttcccc aatcgtctga
    22861 tcgagagtcg ttttggaatt gaccgttggc gcttctgtca caggggcctg ttcaacagtg
    22921 gcttcaccag ctgggacccc ggcttctgct ggttggactt ctgtcacttc agaagcgact
    22981 tgggcaatgg cttccatcgt aggttgtata gccgtcgttt cttctgcatg tgcttgagca
    23041 gttcccacca agaaacagaa ttgagaaaaa gccaccaatg cgagtgcttt caaccaattc
    23101 attttcgttt ttgcatacac aagaattcct ccttttcctg agaattttat ataataaaac
    23161 aaaacgccgt taccaaaagt gataacgacg tgaactgtct cttctatttt tatctggcgc
    23221 tcttatctga acacatttca tcaatgattt taccctccca ctataattac agaacaaaaa
    23281 aagaacctgc ttcgtggaaa tcaactgtcc atttcccaat tggaatacca gcttttttgg
    23341 caacttcacc atcaccaaat ctcatgccat accaattact accttcatcc ttaatttctt
    23401 tccaaccata tgacatagct tcatctaatg aatcaaaaat catgacacta ttgccaattg
    23461 ttacaggatc tggcttaaga tcttctggaa gagaaatatc aatcatacca taatgatccg
    23521 attcctcagt attattgtca ttactagcta ctggtttggt tgttctactg gcttattttg
    23581 atacaacaag tactcttatt cttcttttac ttctccgttt tcaatttccc attcaaacca
    23641 ctccgcaaag tcttgcttaa aaccatctac tcgataccta ttttgtaaat aggcatcttc
    23701 tgacgtcgta ggatctaaat aggtaggttt attctctgga cgagcataga cacctaccca
    23761 tgtttcgtaa tctccttcaa aataactatc taccaaatag cctttttttc taagaatctc
    23821 ccgaacttga tttttaatta ttgatacttg ttcaaaacca tcactcattc tatcacctca
    23881 aataactcta gattctcata aatattcccg acaatttcaa tcctatcaat gatctctaac
    23941 aaatcgctac ttatgcttcc ccattcgtat aagaatttcc cttccgcaaa ataaattttc
    24001 cataaacttc ttcatgatcg tcccaaccaa tatcactctc gaaaaattcc acgttgttct
    24061 tatcttttag ctcagtaaat gccataagtt caacatgttt tccaacctcg aaacaatcac
    24121 accacccatc aaccgttaca cgtgtgcctt caatacctaa gaaactttgt cctcgtgtat
    24181 taaacactaa aactttccgc attttttgct cattaattaa tcacgcgcga aatctaggaa
    24241 tcacaactta ttcgcttctt ctttataaat aaaaaaactc caataatcgg aaattactat
    24301 cttttcctca ttcctttttt aaatcttcat acttcttctt atctttgtcc taacctaata
    24361 acacaaattt tgaagaaaaa ctcagtaaaa cctgattctt tttttatctt cacaacaacc
    24421 aactttttct tcagatcctt ttactagaac ttgtatacaa aaattgttga atgctgatat
    24481 aatttgcggc tacttgaaaa aacgatagat gtaaaaagat aaatagaatc attttttatt
    24541 ctatatcagt ctatgattca ttgcttatca atcacccaac ccattcgatg ccgttttttt
    24601 tagagaaatt taaaaaagac cgtacgaatc tcgcattatc cgattacttt tccagaaaag
    24661 atccccaatt ctgtataaat aaccctatct tcttgttggt ttcattttct catataagaa
    24721 ttcagtcaat ctacccacta tgaccattac tacgtccaac acaactgaca tattaaccac
    24781 gtaagtattc cctcacagat ctccgaatct ccatggtatg gattcccatc ctgacgctgc
    24841 agaggacaac atatttcatg tggctctgta cccttttgat ttggaaacac tacaaatcaa
    24901 tactcatcta taacttatca agcgaacttt cgctaggctt ctagtgatta ctaaattgtt
    24961 ggataacata catagcccat tttatctagc tgttattcat aacagttagt tcttgtatta
    25021 cttcttccgc ttgtgttgcc attgagcttg tcaaaaagtt acttagaaaa aagctgccag
    25081 taaagcaact ttcaacaaac cctttt
//
LOCUS       DADVXV010000036        24416 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.037, whole genome shotgun sequence.
ACCESSION   DADVXV010000036 DADVXV010000000
VERSION     DADVXV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.037"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..840)
                     /locus_tag="KB969_001399"
     CDS             complement(<1..840)
                     /locus_tag="KB969_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6869392.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMD"
     gene            complement(1064..3004)
                     /gene="thrS"
                     /locus_tag="KB969_001400"
     CDS             complement(1064..3004)
                     /gene="thrS"
                     /locus_tag="KB969_001400"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBB6869393.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3341..3520)
                     /locus_tag="KB969_001401"
     CDS             complement(3341..3520)
                     /locus_tag="KB969_001401"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBB6869394.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3567..5390)
                     /gene="cadA"
                     /locus_tag="KB969_001402"
     CDS             complement(3567..5390)
                     /gene="cadA"
                     /locus_tag="KB969_001402"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6869395.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5668..7947
                     /locus_tag="KB969_001403"
     CDS             5668..7947
                     /locus_tag="KB969_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6869396.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8040..8687)
                     /locus_tag="KB969_001404"
     CDS             complement(8040..8687)
                     /locus_tag="KB969_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869397.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8866..9585)
                     /locus_tag="KB969_001405"
     CDS             complement(8866..9585)
                     /locus_tag="KB969_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6869398.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9716..10867)
                     /locus_tag="KB969_001406"
     CDS             complement(9716..10867)
                     /locus_tag="KB969_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBB6869399.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11084..11824)
                     /locus_tag="KB969_001407"
     CDS             complement(11084..11824)
                     /locus_tag="KB969_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6869400.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11828..12151)
                     /gene="rsfS"
                     /locus_tag="KB969_001408"
     CDS             complement(11828..12151)
                     /gene="rsfS"
                     /locus_tag="KB969_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBB6869401.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12208..12801)
                     /gene="yqeK"
                     /locus_tag="KB969_001409"
     CDS             complement(12208..12801)
                     /gene="yqeK"
                     /locus_tag="KB969_001409"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBB6869402.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12785..13435)
                     /locus_tag="KB969_001410"
     CDS             complement(12785..13435)
                     /locus_tag="KB969_001410"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBB6869403.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13445..13756)
                     /gene="yhbY"
                     /locus_tag="KB969_001411"
     CDS             complement(13445..13756)
                     /gene="yhbY"
                     /locus_tag="KB969_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBB6869404.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13772..14881)
                     /gene="yqeH"
                     /locus_tag="KB969_001412"
     CDS             complement(13772..14881)
                     /gene="yqeH"
                     /locus_tag="KB969_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBB6869405.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14878..15405)
                     /locus_tag="KB969_001413"
     CDS             complement(14878..15405)
                     /locus_tag="KB969_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBB6869406.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15585..16370)
                     /locus_tag="KB969_001414"
     CDS             complement(15585..16370)
                     /locus_tag="KB969_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBB6869407.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16363..17232)
                     /locus_tag="KB969_001415"
     CDS             complement(16363..17232)
                     /locus_tag="KB969_001415"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBB6869408.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17233..18612)
                     /locus_tag="KB969_001416"
     CDS             complement(17233..18612)
                     /locus_tag="KB969_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBB6869409.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18620..19039)
                     /gene="fabZ"
                     /locus_tag="KB969_001417"
     CDS             complement(18620..19039)
                     /gene="fabZ"
                     /locus_tag="KB969_001417"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBB6869410.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19064..19540)
                     /gene="accB"
                     /locus_tag="KB969_001418"
     CDS             complement(19064..19540)
                     /gene="accB"
                     /locus_tag="KB969_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBB6869411.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19543..20778)
                     /gene="fabF"
                     /locus_tag="KB969_001419"
     CDS             complement(19543..20778)
                     /gene="fabF"
                     /locus_tag="KB969_001419"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBB6869412.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20797..21534)
                     /gene="fabG"
                     /locus_tag="KB969_001420"
     CDS             complement(20797..21534)
                     /gene="fabG"
                     /locus_tag="KB969_001420"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBB6869413.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21546..22463)
                     /gene="fabD"
                     /locus_tag="KB969_001421"
     CDS             complement(21546..22463)
                     /gene="fabD"
                     /locus_tag="KB969_001421"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6869414.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22570..22794)
                     /locus_tag="KB969_001422"
     CDS             complement(22570..22794)
                     /locus_tag="KB969_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBB6869415.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22847..23809)
                     /locus_tag="KB969_001423"
     CDS             complement(22847..23809)
                     /locus_tag="KB969_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBB6869416.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23819..24259)
                     /locus_tag="KB969_001424"
     CDS             complement(23819..24259)
                     /locus_tag="KB969_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6869417.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         6681 a         5437 c         4248 g         8050 t
ORIGIN      
        1 atccataaaa tattcttgga ttgcttctcg tgtttttttc actttttcgc taagcttttc
       61 gtttttagcc atatagaaat aaaaaatgat atcgatcgta gcaaattggg ccaaaagtga
      121 attagttgcc gcacttcgat tcgtgatttc ttttggtcta gatgtttgta cgagtacatc
      181 ggctatcttg ctaagcgggt tatttccaaa ttgcgtcaac gcaatgattt cgatattcat
      241 gcttttcgcc agctcggcta atgcgactac atctgcactt ctacctgagt ttgaaacaag
      301 ccaaagcact ttctttttct cattgctgac aagttgcggg agcaagacgt ggatatcttt
      361 ttcaaaaatg attggcttac cgacacgaga ccatttttgc agaatatctt ctactactaa
      421 agaagaggcg ccaaccccat ataaaaaaac agtctctgcc gattccaaac actctacgac
      481 tttttggatc gtttcttctt ctagaatatc tactgtttct tttatcgcta cttgtgcatt
      541 gttaccaagt ttgtttttga tagagtaaaa ggactcattt gcttctatat cactaaaacc
      601 ttcatcgatt ccagtctgta gttctgttga aatcgtgatt ttgaagtccg tcagactttg
      661 aaaaccgatt tttttggaaa aacgtacaac tgtcggcgca ctcaacccgg aagcttctgc
      721 taattcatta gctgtcattg tagggacctt ctcaatatta ccgataatgt agttggccaa
      781 ctttttttct gctgaagaat aatcttccat catactttca atacgactaa ttacgctcat
      841 aagttcctcc acccttttaa tgatagtcta tgtaagtata ccatatcaga cccttattca
      901 cggtcgtata ctggataaaa aacaaaaaaa caatccgccc aacagaatat cttatcccat
      961 caatcccaca gattctattg agcatctgtg tctttgagga atacctgtta tctattgttc
     1021 ggattgcttt ctatctacta cttttttaca ggaaatttac ctattagttt tctctgctgt
     1081 aatttttgac ttctgcttcc atagcatcaa taaagatatt caaatcttct acagctgttt
     1141 ctttacttcc ataacgacgt acgttcactg ttgcatcttc caattccttg tctccaacaa
     1201 ctaattggta agggatcttt tgtgtttgag aggcacgtat cttatagccc attttttcat
     1261 tacgatcatc aacttctaca cgcaacccct tcatttgcaa acgttctttg atttcataag
     1321 cataatcgcc atgtgcatca acagaaacag ggatgattgt tgcttgtata ggtgccaacc
     1381 atgttggaaa agcgcctttg tatacttctg ttaaataagc gacaaaacgt tccattgtag
     1441 aaacaattcc gcggtggata actactggac gatgcgtatt ttccccgtct tctccaacat
     1501 atgtcaaatc aaagcgctct ggcaataaga agtctaattg tatagttgat aatgtttctt
     1561 ctgtaccaag agctgttttg acttgaacat ctagttttgg tccgtaaaag gctgcctcgc
     1621 cttctgcttc aaagtaatct agttctaatt catccatagc ggctttcagc attgcttggg
     1681 ctttttccca cattgcgtca tcatcaaaat atttatctgt attgtttgga tcgcgatagc
     1741 tcaagcggaa acgataatct gtaatattga agtcagcata tactgccacc atcaattcaa
     1801 gcgtacgttt aaattcatct ttgatttgat caggacgaac aaatgtatga ccatcattca
     1861 acgtcatttc tcgtacacgt tgtaaacctg acaaagcacc tgatttttca tagcgatgca
     1921 tcattcctaa ttcagcgata cgaattggta attcacgata agaatggatc gtgtttttgt
     1981 agaccatcat gtgatgaggg cagttcattg ggcgaagaac aagcatttcg ccatctccca
     2041 tatccattgg cgggaacatg tcttcttgat aatgatccca gtgtccagat gttttgtaca
     2101 actcaacatc tcccattatt ggtgtatata catgttggta acctagacta acttctttgt
     2161 ctacgatata acgttcgatc gtgcgtcgga ttgttgcccc ttttggaagc cagaatggca
     2221 aaccagaacc tacttctggg gaaaccatga acaagtcaag ttcttttcct agtttacgat
     2281 ggtctctttc ttttgcttct tcacggagac ggatatattc tttcaaagct ttcttgtcaa
     2341 aaaaggctgt cccgtataca cgttgcatca tttgattgtt tgagtttcca cgccaataag
     2401 cacctgccac tgataataat ttaaatactt gtatacggcc agtggatgga acatgtggtc
     2461 cacgacacaa atcgatgaat tcgccttgtt gataagcagt aatcacttct tcttctggca
     2521 attcactaat cagttctact ttgtacggat cacttgcaaa aatttctaat gcttcctgtt
     2581 ttgaaagaac acggcgttcg atcggcagat tttctttgac gattttcatc atttctgctt
     2641 cgattgccgg caaatcttct gcagttactt ggttttgtcc attatctgta tcgtagtaaa
     2701 accctgaatc gatagctggt ccaacgccaa agtggatatt tggatagagg cgacgcatgg
     2761 cttgggccat caaatgagct gctgaatgac ggactaagcc aagtgcatct tcatggtctg
     2821 gtgtgatgat ctcaatactt gcatcttcct cgattggacg agtcaaatca acgagttttc
     2881 cgttcacttt accagctaaa gctttttttg ctaagctttt tgaaatgctt tcagcaattg
     2941 ccaatgttgt tgttccagac tcaaattctt tgactgcacc atctggaaaa gtaattttta
     3001 tcataatagt ttcctccttg aaatgttttg attgatcaga tcatcaagct gaaaaacaaa
     3061 aaaatcctag catctcttga aaagagatac taggacgaaa agttcgtggt tccacctaat
     3121 gttcaaacgc aaatgcgttc ctcaagcgtt gtaacggtcc gaccgccctt gcttcaacaa
     3181 gggtttcgaa agtggtcatc ctttggtttt ctcctggaaa agtttcagcc tagcttttcc
     3241 tctcttatcg aagactctca aattcagttg gctttctcat caatcaatta tgtgtttatt
     3301 taaccactaa taaatagaaa aatcaagtgg gaaactaaac ttattttttc cattccccat
     3361 ttacaccgta tgttcctttt ttcatctcat tgatgatgac atggatgtgt tcttttggtg
     3421 cctgcgtgtt tttatgaaca gcttccgtga tatctttcat catattttct aattgttccg
     3481 gactgcgacc ttctactaat tcgacatgta cgaatggcat aatgctctct cctctttctg
     3541 atcgttcttt tttcaactcg attctatcat actatgtttg tcttgggtac tgaatcagga
     3601 aaaatggctg gatctttttt tgctctcaag gcactcaaaa tagagaccgt atccacgact
     3661 tcttgcaaaa cagctccgaa taatgcgggg attagtcccg tacttgcaat taacatcaaa
     3721 aaaatacaaa taaagatgcc aatcagtaca gactgtttcg ctattctcat cgtatctctt
     3781 gaaatcacta ctgcttttgc tacacgcaag agatcatctt tcaagatgac cgcatctgca
     3841 ctttcactag cagctgtaga accatgagcc cccattgcaa taccgatatc tgcagcagca
     3901 agtgctggtg cgtcattcac gccgtctcct accatcgcaa caggtctttg atctttaggg
     3961 atactttcta aaatggtcag tttatcttga ggcaagctac gggcatgtac agaatctaat
     4021 tggacttttt ctgcaatcgt ttgagcaatg gcagatccat ccccggtgat catcatcaaa
     4081 tttttcacat caagttttct tagctccttg attgtctttg ctgcttctgg gcgaatctga
     4141 tccgaaaata ggatcgttcc tgcaaaagat cgatcaattg ttacatagat tgctgtattg
     4201 gacgtttcta tttcttcagc tgaaacaaaa gaggcacgtc caatctttac ttcatgatta
     4261 ttgactactg cttggattcc ttgaccggtc acttctttca gttgactaac aggatacagt
     4321 tggctgtttt tcacgttgtt cactaacgaa cgagctaaga tatggctaga ttcctgttct
     4381 gcactagctg catacagaag tagctcttct ttttttattc cattgactgg ctgaatcgcc
     4441 tctacttcca atatcccttt ggtaagcgtt cctgttttat caaaagcaat cgtttttgta
     4501 cgtgcgagct tttcaatcgt tgttccagtt tttacaacga tcccgttttt acttgaacgg
     4561 ctcattcctg caactaaagc aatgggcgca gctagaatca gtggacaagg tgatgccact
     4621 accagtacct cagcaaatcg taaagggtct tttgagaacc accaagaaat accaccgatc
     4681 aaataagcaa tcaacgtgaa agggactgca taacgatcag ctaaacggac aaatcgggca
     4741 ggcttttctt ttgattcttc gactagttta ataatcattt gatactggct gtctgcggca
     4801 cgtttttcag cgatcatttg gatcgatccg tctccattta aagaccctga cataatctga
     4861 tctccaggtt tcttggtttc cgggcgggac tcacctgtca aagaagattc atcgaccgaa
     4921 gattctcctt tggtcactcg accatctgcg ggtacaagtt cgccaggctt gactagtaac
     4981 tggtcatcaa tatttatttc atcgattact atatcctgca attttccttc tttgaatcga
     5041 tgggcaattc ttggggtgtt atctaacaaa gactgcagtt ctttacccgc tcgtttattc
     5101 gcgtaatcct ctagactatc tccgcccgta agcatgatca atatcatcaa actagcccag
     5161 tattctttga cggctaatgt tgcaaggatt gcggtaatcg ctaatacatc tacgccatat
     5221 cttcctgaac gtaacgtctt gatcatttcc aaaaacatca agaaggcgag aatccctcca
     5281 gtaaatgcga caatcgcaaa tgcaagggcc ggctggtgaa aaacaaattc acttaataaa
     5341 gctatcccac caataagcaa agtaagtaaa aattttttga aatgtgtcat tgttttttct
     5401 cctcttttat gtgacttaga gaggttagta ataaatttcc agctgcctct ttcatcttaa
     5461 gcatagtcct tgactagcac tttttaaaac aataggcctt aattgaaaac aactatcact
     5521 atcagcgttt ccaaaattca tcagttctac aaacaaaaat attcagcaag gattactttt
     5581 tcgattcatc agttaaaaag tacctttttt cgaaaaacta tgctatactt ttaattcgtt
     5641 atttacggcg gaaggagcaa acatgcgatg aatgagaaac aactagaaca aacgcacgtg
     5701 gatgaaacga tcgaactaat ccagatcgaa caaaatatgc tggatacaaa acaacaagaa
     5761 ttgactcagg aaatgaatca ttcgacaaaa gacacagcta atcacaagat tcgagctggt
     5821 tccaatgaag ctttttatga atctgctgtt gaatatcgcc aacatgagca ggaattgctt
     5881 ttgaaatacc atactcttga agcacagcaa aaacgcctgc aaacgttgtc tgtcatgaaa
     5941 gatagtcctt attttgcccg tatcgacttt aaagaagacc gtgaaacaga aacattatat
     6001 ctaggtatcg cttctttaag agatctggca gaagaaacaa tcgttattga ctggcgcgca
     6061 ccaattgcca atctttatta tgaaggtgag attggtcccg cattttatga aactgaaaca
     6121 gatagaatag atgtcgatct gcagttgaaa cgacaattta aaatccaaga aggacgtatt
     6181 ttatctatgg tagatacgtc ggaagtaatc aatgatgact ttttgctaga gatattggat
     6241 gaatcatcaa gcaaccatat gaaaaacatc gtctctacga tacaaaaagc acaaaatgca
     6301 atcattcggg acacaacaag taaagtaatg ctgattgaag gaatcgccgg aagtggaaag
     6361 acatccgctt tgcttcaacg tattgctttt ctgttgtatc ataatcgcaa gtggctcgag
     6421 gctgaaaacg ttcttctatt ttcacccaac catttgtttt ctgattacat ctcgactgta
     6481 ttgccttcat taggtgaaag cggcgtgcct acacagacat tcaaaaatta tttggtgcag
     6541 ctgctgccag agttttcttt actagatgaa cagcaacaag aaagtggttt tttgctaggg
     6601 gaaaaagatc cgatacaagt gatgaaaagc ggattgacct tagtcgatca gattgatcgc
     6661 tatatccaag gcatcacaaa ctacggtccc ttgttccgtg atatgaaaat aaatggccgt
     6721 acgatcctat caaaggaatc gattcgccaa tggtataaag aaacaaatga acaattacct
     6781 ttacatcata gactttctct attacaaacg aagctcctga aaaaattagg cggtctgcaa
     6841 aaagacgaaa cacgtcagca atgggtcaaa gatctggcgg aagaacagct ccaagaacta
     6901 tacgcaacag atccaaatct tgaatataca gaacaaaagg agcgttcatt acgtaaaaaa
     6961 ctggccaacc aaatcgtacg taaaagattc cgtcgaatcc atcgagggat catgaattat
     7021 caatttgtca atataacgaa acaatatctc cactttctac aaactgtgcc actttctctt
     7081 ctaacacgac ataaaatcag cgagaccagg tggcaggaac atttgacaac tgttcgtaca
     7141 cacttgcgtc aaagagaatt gcgtcaagag gatgctgtac tattcttttt actgatgcgc
     7201 cgaacatatc cagtgacggt tacacacaaa gctcgctata tctttattga tgaaatgcag
     7261 gatttcgcac catcacaagt ggcattgctg caagccttgt tcccaaaagc aaatttgact
     7321 ttctgtggag atctaaatca aaatgtcttt ggaaatgaaa cgatcgttgg atcattggaa
     7381 gaccttttcg tggaccgtga agtcactcgt ttccaattaa cgacaagcta tcgctccaca
     7441 aaagaaatca ctgattttgc taatcatttt attgtgaaag aacatcaagt agaaacaaca
     7501 gcaagaaaag gagaccttcc tttgctcatc caaggaacaa cagatgatat caaattgaat
     7561 tggttagcag ataccattcg aacgactcag ggaaaagccc ggtattggcg tacagcaatc
     7621 atagctaaaa cacaagaaga atgcgaagct ctttatgctc aactgccaga cgagttgaaa
     7681 caacaagtcc agctgatttt aaatgagagt gactttatga agcgttccat tattttactt
     7741 ccagcctttt tagcaaaagg tctggagttt gaccgagttt tcttgtggga tgtagatgca
     7801 gaacattttt cttctcagca agacaaattg atcctttaca ccatgtgtac acgtgcgatg
     7861 catgaattga ccctttttac ctccaataat gaaagtcctt tgttaaacaa tatggatatt
     7921 tcatcttatg agaaaaaagt actgtaagta aaaagacaac tgctatcatt aatgttagca
     7981 gttgtctttt tatttacaat aataattgca gaaaaagtaa ttcaatcatt taaggtcatt
     8041 tattctatat ataaatccaa atctgtttca ggatatttta atttgacaag cgaaataatc
     8101 attttcagtt cttccatgtt ttctggatat tctgggtcaa ataccttgct atgacggcca
     8161 atcccgccat tgtcgatcaa tcggtaaatt cgattccatt caatgaattg gtcaattgat
     8221 tggaaattgc tgattggata gccgccacaa tccaaaatct ctgatacacg aaatgctagg
     8281 tatgcactat cgatcacttt attttttttc gtgtctatct tctcatttct ttcgataaga
     8341 attttttcag gacgatgttt caagctccac tctaatagta gaaagaaagc ctccatccga
     8401 tactcttctt caaataaccg aaaggctgaa tcagaacgac gaaaaagcag cggaatcaga
     8461 taattttgtc tataaatcag cattggtgcg cggtccacca tacactctaa ataacggttc
     8521 agataccctg taccgacata gtttcctaat cgatagcctt caacgccgaa tcttgcgtat
     8581 ttttgcgcta attttgaaca atcagttacg ttcacagcta actcttctac tttgcggtaa
     8641 ccgcttaaga tacgttcaaa aggttctaaa gtgatttttg cttccatatt cttccccgtc
     8701 catcttccac atacttcata tcatttcaca tgatacttat gctctcatca taccacaggt
     8761 tgaattagaa aagaaaataa atcacacaaa aaagcaagac aatctgttag tgagattgtc
     8821 ttgcttttcg aaaaagactg aatacttttc gttaaaactg gttgcttagt cttctaatgc
     8881 cacattatgg aacacatgct gtacatcttc tagatcttcc agtgcatcaa tcattttttc
     8941 aaatgtttct tgatcttctg gagatagtgt tacctcgttt tgagggatca tttggatctc
     9001 agcgattgaa aaatcagtga ttcctttttc ttttaatgct tcttgtatac tatggaaatc
     9061 cgctacttca ccgtaaacga tgatttgtcc ttcttcttcc attacatcgc gaacatcgat
     9121 gtctttttcc attaggtatt caaggatctc gtcagcgtct tctcctgcaa aagcaaagat
     9181 tgctgtattg tcaaacatgt aagaaaccgc tccggaaaca cccatgttcc cgccattttt
     9241 cccaaatgct gcccgtacgt ctgctgctgt tcgattcaca ttgttcgtca atgtatcaac
     9301 aatcaccatt gagccgcttg gtccaaatcc ttcatagcgc aattcagagt atgtttcatc
     9361 tcctgcacct tttgcttttt cgattgctcg gtcaataata tgttttggta cattataagt
     9421 tttagcgcga tcaatgacga aacgtagttt ttggtttgca tgcggatcag gatcacctga
     9481 ttttgctgcc gcgtagattt caatcccaaa ttttgcataa atccggctat tattagcatc
     9541 tttagcagtt ttctttgcta cgatatttgc ccatttacgt cccatatttt cacttcgctt
     9601 tctgatttga tagtttcata acgcaaaaac gtcctgttcc attatacttg tgaatcacga
     9661 ttctgtgaag ctttttttct ttcttccttc attcttctca tttttagtca attatctata
     9721 ctcggattgg gatttgcccg aaattctgtt ccggaatatt gcctcccaat tgatagattt
     9781 gatcacttct aactaacagt tccgcttctt gtgcctcttt ttttccgatt cgggaataaa
     9841 tagaaatctc ttttttttct tttaagaatc ttcttccagc atcggtaaat ccaagtagtc
     9901 gaagataatt tttattttgt tggacaggaa tctcttgctt tttgatattc agcaagacat
     9961 aacaagataa tcgttggatc cgtgtccatg tatatctttt tgtttttacc tttgacacaa
    10021 aatcctcaaa actatcagca gttgcagctg ctgttttcat gcgcgattct attccttcgg
    10081 tcatctgata gatatctgtc agttccagca aagtagaaga taacaaccga taacgcaaat
    10141 acggccaata agattcccaa gtctgcagcg aacaagttga aagatcttct tctgtctgag
    10201 gcggcacaag tccagctatt ctttttcctt cttctaacgc atggcgaatg gctgttgcac
    10261 tggctatcct ctgatctgtg atgatttttt catgatagcc tgcactttta cgtcggatcg
    10321 gatgtaattc catagggtgg acatacttgg cattttcctt tgcataactt aatcccaaga
    10381 tatgatttgg cgaagaaaaa tcaagcgtaa tatcgggata cagactgcga aaaacctcag
    10441 tcattttttg cggataacta tacgtttgat cagacagttc ttgaaatgcc tcttctatcc
    10501 tatcttgatt ctcttggaca aagcgtccga aactgctgta atcaaacgaa gtctcttctt
    10561 ctgttccaaa acacaaactg tcacagtcca gtgtttgcaa gatttttact gcacctttag
    10621 caaaatagtc agctgactga accgcccatt cgacgggaag ctccactact aaatccacac
    10681 cattttgtaa agcttcattc gcgcgatgcc atttatcgat gatagccggt tcgcctcttt
    10741 gcaaaaaatt cccgctcatt acagcaatga cgacctctgc tcctgttatt tttcgtgcca
    10801 tttccacatg atagcgatgt ccattgtgaa aaggattgta ctctacgata atcccgcagc
    10861 ttttcatgcg catcctcctt catagttatc gataaaaaag aaatagagac aagtaaaaaa
    10921 aggcaaaaat cggaaaaaat acccgaacta tataaactat tctcgcaaac acaatacttc
    10981 tgcgacgaaa agctgcactg caagagcaat gcctatatcg ttcggatata taatttatgt
    11041 tgaagattta ttcttttctt gttaactcga gcaggcaaaa ccgctagtct ttgtatgcta
    11101 caaagaacca gcgctttgat ttctctgatg ctgcttcgtc tgtaaaatca gaaaatgctt
    11161 cgactttcga aaagccgctg ttttccagca ttcttaaata actttccaat ggataggtac
    11221 gctcttgatg tagttcatct tcacgaataa atcgaccaga cccttcttgt tcttcaacga
    11281 aaaaggtaag aaaatgttcg atgctgtgtt tctcgcttcc tggataacta tcccacaaaa
    11341 aagcaaaatt atccccttga taatgatagc tatattctgg aaaaacctca tctacttgat
    11401 aggtggagtg tacgtcaaat aaaaatcggc cattttcttc taacgcttga tagacttcat
    11461 caaacacttg ctgtacctct tgtctatttt tcatatagca cagcgaatca gaaaaacagg
    11521 taattgcctg atattgtccg atttctgata aatcgagcat attgccttcc acaaattgga
    11581 tcgatgcgtc ttcttcatat gctcgctggc tggcaatcat caacatctct tctgaaaggt
    11641 ctaaccctgt cactttatat ccatcttttg caaaggcaac cgctaatgct ccagtaccgc
    11701 atgccagttc caaaatattt tttgtgtctt cttgtaaatg acgtttcgaa aaagctaacc
    11761 attgctgata aagtgtttcg tccatcactt catcgtaaat gaaagcaaat gtttcataag
    11821 ccatatgtta atccaaccat tcactaagat cgactagcgg agcatctgac catagttttt
    11881 ccagattata gaaatttcgt tctggcgcat ggaaaacatg tacgatcaca tctccaagat
    11941 cgatcaatac ccattttccg ccttcttttc cttcaatacg ttttacttca tatttgtttt
    12001 cttcttcttt atcaatgatt tcttctgtaa ttgcgttgat ttgacgttcg ctatttgctg
    12061 aacagatcat gaaataatct gccaacaagg aaacatttcg aacgtctaaa gcgataatgt
    12121 cttctgcccg ttttgaatct gctgcttcaa tcgcaatttt taattgttct ttactatcta
    12181 tgatgatttc ctcctaatat gagcagctta tttttttgct acccagtaat tatatgtttc
    12241 gattgttttt ggataaatct gttgttcttg cgcaagcaaa tgggccaatg tatgttttgt
    12301 ttcaaatgct acagcttcgt ctagatcagc ccatgcaatg gctcgtgcat cttgtacccc
    12361 aggaaaatct cgacctggtt caatatagtc tgctacataa atgattttgt caaggagact
    12421 catcttagca gccccagtcg tatgcacccg gattgcatga agaatctctg catcggtgat
    12481 tcctaattcc cgctctacaa acgaagcgcc aacaagacca tgccagattg cattattata
    12541 attcaataac tccggatcaa aaccgtctct tacgattacc attttgaact cctcatctgg
    12601 tcgttctttt gcataatcat gtgtcaatgc agcaatacta gctttttcag gagaagcacc
    12661 gtattttttg gcaagagcca cggctgtttc ttctactcca agcacatgct tgaagcgttg
    12721 ttcgctcatt ctcatctgta ttttttgcat caggttttct ctagaataag cagtatattc
    12781 attactatag tccatattca tacaaccctt cattttgaat ataatcaatt actttatctg
    12841 gaacaaggta gcggatagaa cagccttctt tgatcttttg acgtattttc gtggaactga
    12901 tgtcgatctc aggtacatct acccaaatta caggatatgg agtatccgtt gtgtatcctg
    12961 gtcgacgtat acccacaaag ttgaccatag aagtcagctc atcgatttta taccattttg
    13021 gcaaatattc taccatatcc ccaccgataa taaagtaata atctgtatcc ggattgtttt
    13081 gcgtcaattc cttcatagta tcataggtgt aacttttccc accacgagct aattcaatcg
    13141 tttcaatctg caaaaaagga ttgtcttcca ccgctaattc caacatgttg agtcgatgtt
    13201 ttgcatcaat cgtctgtttc tcatcaacat gaggtggctg ataagaaggc atcaaaaata
    13261 cgcggtcaag acctaaattc cggccagctt gttcagccat cactaaatgt gcaaggtgaa
    13321 cgggattgaa tgttccgccc aagatcccta cttgcttttt cttctctaag aattgaggca
    13381 tttcttcagg aaataattgt gaacgaacaa atgtcttagc ttgcgtattc atcatggtca
    13441 ctccttatat tgcttttact tcttttgata gcctttgata cttttctttt gtggaaggtt
    13501 tgtataatac aataacacgt ccaatgattt ggacgatttc gcaatctatt tctttttcta
    13561 atacttgagc tgcttcttct gcaatctcat ctgtattttg aagtaacgat actttgatca
    13621 gttctctttt ttctaaagct tcttcaattt gaacgatcat tgctgaattg atcccacctt
    13681 ttccgatttg aaaaatcggc tgaagatgat gcgctttgct acgtaaaaaa cgcttttgtt
    13741 ttcctcttaa actcataatt ttccttcttc cttaaatcaa tgctttgcgt ttcaatacat
    13801 ctacaccctt tggcgcccag cccgcaatta ctactggcgc tgttacagtg atccagccta
    13861 gaccggcaaa aacgatgtct gttttttctt tcacagaaaa ctcaaaacga acaagctccg
    13921 gaaatgcctc gacttcatca ggacgaggag gctgtaataa tccacctaca tgtttttgat
    13981 aaaattcgtc tgctttttcc agtttcgttc gatgaatatt tacatcattt gacacataag
    14041 caataaatga agcacgattg ccgctgataa aatcaaatct tgcaagtccg cccaagaaaa
    14101 gtgtttgccc ttcattcagc tgataaactt taggtttgat ttcttttaac ggtgcaatga
    14161 tccgcaaatc ttttttacct aagtagtgcg ccatttgatg gcgatggata attcccggtg
    14221 tatcaatcaa aaaatgcccg tcatctaaag gaatctcgat tttatccaag gtcgttcctg
    14281 gaaactgcga agttgtgatt acatcttgta ctcccgctgt atttttgatg atttgattga
    14341 taagcgtcga ttttccgaca tttgttactc cgacgatata gacatcccgt ccatcgcggt
    14401 attcttcgat tttttctaat agttccgtca tctcatgaga tttcttagca ctagttaata
    14461 atacatctac tggacgaatt cctgcttcgt aagcacgttc cttcatccat tgtgttaatt
    14521 tagttttttt caatgattta ggtaatatat ccactttgtt cccaactaaa agtactggat
    14581 tgtcaccgac aaaacggtgt agtcctggga ttagtgaacc attgaagtca aaaatatcca
    14641 ccacattgac gatcaatgca tctttttgcc ctaattcatt cagtaagcgc aaaaagtcgt
    14701 catccgtcaa tgagacatct tgggtctcat tataatggcg taatctgaaa caacgctgac
    14761 aatagacttc cccggaagct aaaccttttt ccaaagccgt ttgcggcgtg tatcctaatt
    14821 caccgggttt gtttgtttgt ataacggcac cacagccgat acattgtaat tcttctgtca
    14881 ttcgattcca cctcgccagc ccatatcagg gtgttttgct aatagatagg ccataattct
    14941 tttttcccaa aaacgattaa attgtgtctt ccaactatct gttgcgataa tgggttttac
    15001 aaggatgcta cgtatccctg cacgattggc tccacgtata tcagtcataa tctgatcgcc
    15061 taccattact atctcatcat ctgctaaatc caattgtttc tttgctatgt tgatccctct
    15121 tgctaaaggt ttcattgctc gtgcaacata caaaagatca aatttttcaa tcgctcgcgc
    15181 gacacgtttt gaattattgt ttgaaacaac aacaacaggg attcctgcat ttttcatttc
    15241 taaaatccaa gtaagcaact cttctgttcc atctggatta ttccatgcaa tcaacgtatt
    15301 gtctaaatcg gtcaatactg ctttgatgcc tagattcttt aattgggcag gtgtaatctg
    15361 atagatggct tctaccatcc atgttggttt gtaatttgaa aacatgctgt ctcctcatct
    15421 gcaaaaaatg aaggagcaca taaagtactc ctcaaccccg tattatactg catatcagca
    15481 aaaaaaacta cctctatact cgttcgtctt tcagaaaaag catttcttta caaaatgacc
    15541 aaaaataaag attgatcaca gaaaaattta gaaacaaaaa acaactaata ttggcggaac
    15601 ctcttgtatc gtttttccag taatttatgc tgatctaatc gaacaagttc cgtcaatctt
    15661 tcaatcaacg cttttttcat aatgtgtgcg actttatatc gtggcaactg ctcgccgttg
    15721 aacgtttcag gaataactcg atcaacgatt cctaactcgc gtagttctgg cgcagtaatt
    15781 ttcatcaact cagctgcttc tgcggcgcga ctaccgtctt tccacaaaat cgacgcaaat
    15841 ccttctggag aaagcacagc ataaatcgtt tcttccagca tccagacttc atccgctaaa
    15901 cctagagcaa gggcaccgcc acttccacct tcaccaatga tgatggcgat gatcggtacc
    15961 tttaaatcag acatttcgag cagatttctg gcaatagcct ctccttcgcc gcgctcttct
    16021 gctcctacac cgcaatatgc acctgctgta ttgatcaagg taatcaccgg tctattgaac
    16081 ttttccgctt gtttcatcag tcgtaaagct tttcgatagc cttcaggatg gggagaacca
    16141 aaatttctgc ggatattttc ctgcagatcc cgtccttttt gaataccgat cactgttacc
    16201 ggtttgccat ctaatcgagc gattccacca acaatcgctt cgtcatctgc aaataaacga
    16261 tcaccatggc attcctcgaa agaatcgaag atctcttcaa aaaaatccaa gcttgtccat
    16321 cgttctttag ctcttgctaa ctgaacgaca tcatgtgctg tcttatccac gatctatcca
    16381 tcctttctgt gtatgcaatt caagaagcgt atggattttc tgtttcaatt ccatgcgggg
    16441 aacaatctga tcgacaaaac catgagataa taagaattca gccttttgga aatcttctgg
    16501 aagttcctgc ttgatcgtct gttcgatgac gcgtcttcca gcaaaaccga tcaagctttg
    16561 gggttctgct agaataatat cgccttccat tgcaaaactg gcagttactc ctccggtcgt
    16621 cgggtccgtt aaaacagtta gataaaaaag accttcattg ctatgccgtt tgacagcagc
    16681 agagattttt gccatctgca ttagagaaaa gattccttct tgcatccgtg cgccacctga
    16741 agctgtgaac aagacgactg gaagactttc ctttgttgct cgttcgaata atctggtgat
    16801 cttttctccg acaatcgttc ccatacttcc catgataaaa ttaggatcca tcactccaat
    16861 aatgaaggga atcccctgaa tggttgcttt accagtgagg actgcttcat gaagtcctgt
    16921 tttatcttgc atttttttaa ttttttccgt atattcggga aatgctagcg gatctttggt
    16981 tacaagatcc gtatcccatt cttcaaaact tttttcatca ataatcaaag ctagacgctg
    17041 ccatgcaccg attcgaaaag cgtatccgca atgagggcat actttttctt caccgatgtc
    17101 tttcgtataa aggatatgtt tgcaatttgg acactttgcc cacatgttat caggaacaga
    17161 tggcgagtta gcaggtttgc tctctctatt aggattgatc cgaatatatt tctttttctt
    17221 aaacagagcc atctatgcgc ctcctatctc cgtttctggt gtccaattcg gtaaaaattc
    17281 ttcttgtaaa aatgctgtgc tgtaatcacc tgctatgact gcaggatgac taatcaaatc
    17341 catctgaaat tctgcgttcg tgatgattcc ttctgtgata aattcactta aggctcgctg
    17401 catcttcatt aatgcttcaa aacgcgtatt tccatggacg attatttttg caatcattga
    17461 atcataatat ggcgggatcg tatatcccgg gtaaactgca ctgtctactc gcagtcccat
    17521 cccacctgct ggaagcagta agttttggat cttccctgga gaaggagcaa aatggaaagc
    17581 aggattttct gcattaatcc ggcattcgat tgcgtgtcct tggaatacta cttcttcttg
    17641 acacacattc aaaggctcac cggctgctat ctccacctgt ttttttacta aatcgattcc
    17701 tgtgaccatt tctgttactg gatgttccac ttggattcga gtattcattt ccatgaaata
    17761 aaaatcgcct tcttcatcca tcagaaactc gatcgttccg gcattttcat aattgactgc
    17821 tttagctgct cgaacagcag cgtctcctag tgcttctctt tttgtttgtg agatcactac
    17881 agaaggagat tcttccagta ctttttgatt gttgcgttgt aaagaacaat ctcgctcgcc
    17941 taaatgaatg acatgaccaa atcgatcacc taagatctga acttctatat ggcgagcagg
    18001 ataaatgatt ttttccaaat acatatcatc atttccaaat gccgctgctg cttcttgctg
    18061 agctgaagaa aaatgctgtg ggagctcttc ttttgattga actttccgaa tgcctttccc
    18121 gccaccacct gcagctgctt tcagcatcac tggataacca attctgtctg ctatttccaa
    18181 tgcttcttct actgtagata atacaccagt acttcctgga atgactggga catttgcttc
    18241 ttgcatcaat tgacgcgcat tgatcttatt tcccattgca tcgatcgttg cacttttagg
    18301 accaataaat gtgatattgc actcttcaca catggaggca aatcggctat tttcagataa
    18361 aaaaccaaat cctggatgaa ttgcttcggc ttttgtcacg attgcagcgc tcagtacttc
    18421 ctgaacattc agatatgaat caacggcttt tgccgggcca atgcagattg cttcatctgc
    18481 taactgtgta tgaagtgctt cggcatctgc ttctgaatat atcgctacgg tttggatccc
    18541 tagttcgcgg catgcacgaa tgatacgtac agcgatttca ccgcggttag ctatcaatac
    18601 tttagaaaac atatttcacc tatccaatca taaaggttaa ttccgcttcg gctacttttt
    18661 taccgtctac tttagcgatt cctttgccta ttccggctga agctttcact ttcaatatct
    18721 caacttcaag gtataaggta tctcccggtg taactttctt acggaatttt gctttgtcca
    18781 atccgccgaa ataagccgtc tttcccttga attgttcaag agaaagtaat gcaactgctc
    18841 ctgcttgagc cattgcttca acaatcaata cccctggcat aacaggttct tctggaaaat
    18901 gtccttgaaa aaagggctca ttgatcgtta catttttctt agcaacgatc cgttctcctt
    18961 caaccatttc ttccactcga tcaatcaaaa gcattggata acgatgtgga atgatttctt
    19021 ttatttcttg tatgttcatt gttttccctc tttcctgctt tgcttatttt tgctgaatcc
    19081 taaagagtgg ctgtccatat tcgacaactg actcgttttc tacaaggatt tctgtgatca
    19141 ctccgtcggc ctcactagtt atctcattca tcagtttcat cgcttcaata atgcagataa
    19201 cttctccttt ggcaacttga tcacctactt ttttgaaagc tggtttgtcg ggcgctggtt
    19261 gcagataaac gattcccacg attggcgaaa caacctcgat tccatcaaat actgccgatt
    19321 ctttttcttt cattatttct ggagcagttg ttgcttgttc aggtatgaca ttgactggct
    19381 ccgaaactgg caacgtttcg tttgtttgaa ccatattcat gcctcgactt gttttatttt
    19441 tattcatata caattcaaat tgaccttcac gcaaatcgaa ttccgttagc gaggattgat
    19501 caaattgact gactaattct ctgatttcat tgatatccaa aattattcct cccagcgttt
    19561 catgcacaga accgcattat gtccgccaaa ccctaatgaa ttactcattg cataagtaaa
    19621 acttgcaggt ttgctttcgt ttttgacaac tgtcaagtca atctcaggat cttgtttttc
    19681 tacattgatc gtaggtggga taaattgatg ttctaatgcc agcaaagttg ccaaggcttc
    19741 gatcccgccg gctgctccca ataaatgtcc agtcatcgat ttcgtgctgc tgacgtaagt
    19801 atctctgaaa ttttcaccta atgcgatttg gattgctttt gcttctgcct ggtcattggc
    19861 tggtgtactt gttccgtgag cattgatata tccgacttgt tccggctgta caccagcttc
    19921 ttccatcgca agcttcattg ctttagatgc accagaacca tctggagtag gagctgtcat
    19981 atggtaagcg tcacagtttg caccgtatcc aacgatttct ccatagattt tggcaccgcg
    20041 agcttgtgca tgttctaaag attcaagaac tagaacgcct gctccttcac ccatcacaaa
    20101 accattccga ttttcgtcaa acggaatcga accacgatta ggatcagttg attctgagag
    20161 tgctgttaaa gctgcaaatc cagcaatccc catctcacaa atcgttgctt ctgttcctcc
    20221 agcaagaatg acatcagaat agccatgttt gatgttacgg aatgcttccc caattgaatt
    20281 cgttccgcta gcacaagctg ttacgatagc tgtacaaata ccttttgcac ctacacgcaa
    20341 agcaatattt ccagctgcca tgttggcaat cgccattggt acgaacattg gagaaactcg
    20401 ttttgcacct ttttcatgta gacgaataac ttggttttcg attgttggaa gaccaccgat
    20461 cccagatccg atgatgacgc caaaccggtc ttgattcatt ttttctttat ctaaaccgct
    20521 catctccatt gcttctaaag cagcgtagat tccatagatc gaaaacatat ccattcgttt
    20581 gctatctttt ttaataaaat atttatcgta agggaaatct ttgacttcac ccgctaaggt
    20641 aatccctgtt tctgaagcat caaatttagt gatcggtgcg atgccattcg tcccctcttt
    20701 taagctattc aaaaagctgt ctgcgtcatt tccaataggt gaagtgactc catagccagt
    20761 aattaccact cgattcattt gtttgctctc cttttcttat ccgtgcatga ccaatccgcc
    20821 atcgacattg atgacttgtc cggtgatata tggattttgt gctaagaaaa ctgctgtttg
    20881 tgcaatatct tctacttgtc cgaaacgctg catcggaatt tgcttttccg cttgttcctt
    20941 gactttgtct gctaaaactt ccgtcatatc agttgtgatg aatcctggcg caatggcatt
    21001 acatgtaatg cctctagttg cagcttctcg tgccacagat tttgttaatc ctactacgcc
    21061 agctttacta gctgcataat ttgcttgacc aatatttcca atcaacccag atacactaga
    21121 gagattaatg atggcccctt ctcgctgctt catcattttt ttcaatacgt gctgcgtcat
    21181 attgaaggtt ccaatcaaat tgatatccag acattttttg aaatcttctg catccattcg
    21241 catcacaagt ttgtcatttg tgattccggc attgtttact aacacatgga tcgatccaag
    21301 cttttcttct gcttctttga tcatttgtcc cgctttctca taatcagaga tgtcaccgga
    21361 aactcctacg cattttacac cgaatgcttc gatttcttct atcttttctt ttggaatctc
    21421 tccgcgacca ttcaaaatga tatttgctcc agcttttgca aaagctaagg ccatcgcttt
    21481 gccgattcct cttgtactac ctgtgataaa tacatttttt ccttttacat ccataacgtt
    21541 cctccttata gtattgctat tgtttcatca aatgtctgct tattctcaac acgcagaact
    21601 ggtattgttt tatcgatttt tttcataaat ccgcttaata cttttccggg gccgacttcg
    21661 atgacttgtt cgatgccgat tgtttttaac ttatggatac tctcatagaa acgaacaggt
    21721 tgcatgactt gctgttcaag tagtcccgcg attgtttctt tcttcattat ttccgttgtt
    21781 gtgttgctta tgataggaaa agaaggttca gagaattgaa tctgacttag gtccttcgcc
    21841 agtttttttg ctgccggttc taaaatagct gtatgaaaag gcccgctgac atttagaggg
    21901 atcattcttt tgaacccttt ttcttttaat agtaaaacag cttcgtctac tgctttttct
    21961 tcgccaccaa tcacgatctg ctgaggtgta ttataatttg caggagatac gatgccgtac
    22021 ttgctagctt catgacagct ttcctcgatc gtttcaatcg gcgcattcat cactgcaacc
    22081 attttcccgc ttccagctgg ggcagcttct gtcatataag cgcctctttt tgctactaac
    22141 gcaactgctt cagtgaagga tagcgcatta ctagctacta atgccgaata ttctcctaaa
    22201 ctcagtccta aagctgcatc tgggatgatt ccatgctcct tcaataagcg ataatacgcg
    22261 atgctgactg ttagaatagc tggctgtgta tattgcgtct gatccaaacg ttcattttct
    22321 gtaaagcaaa gttcagccat atcgtagccg agaatctcac ttgcttcatc aaatgtctgc
    22381 tttacaacgg cttcttcata taaatctttt cccatacctt gatattgtgc accttggcca
    22441 ctaaataaga atgctgtttt catgtttttc tccaatatat ccagaatata tgtttgattc
    22501 ttcctattca aaaaggccga gacattccta tttcaggaaa tgtcccagcc cccaacctaa
    22561 ttttaatgat tatgcagttt gtttttctac gtaagtcact aaatcttgaa ccgttttgat
    22621 tccgtcttct gtttcgattt tcacgtcaaa ttcatcttca atttcattga tgatttggaa
    22681 taaatccaag ctgtcagctt ctaagtcttc ttggatgtca gtagtcaatt tgatttcttc
    22741 agtttctttt cctaattctt ctgcgatgat ttcttgaatt ttttcgaata ccataataat
    22801 atattcctcc gatattgttt gctttttatt tttataattt aacagtctac aactccatga
    22861 gaatacttcc ccatgttaaa cctccgccat agcctgtaaa tattactttc tgctgttttc
    22921 ctaaggtgat ctttccacta gaaactgctt catccaataa gatagggatg cttgcagcag
    22981 atgtattccc atatttatcc atattggtca ggaacttttc ttgcggcatc tttacttttc
    23041 gggcaatttt ctcaataatt ctgaggtttg cctgatgcaa aagcagataa tcaactggtt
    23101 tgtctttcat gacttcttgg atattgtttg caacgtctcg tacggcaaaa tcaaaaatat
    23161 ctctgccagt catttgcaaa taatacgaac cttctgaatc ttctgaatag aacggatttt
    23221 tattttgctg gtagccagcg gtcaatgagc tacttctggt accgtcagct gctaattttt
    23281 ctttcagcaa ttttttctgt ggattcgctt ctaagagaat cccacctgct ccatcgccaa
    23341 acaacacagc agtcgtacga tcagaccaat cgattagctt agatagtgtt tcaccaccaa
    23401 tcaccagtcc cttagttgag ccgcagcgga tcattttttc agccatgctt aacgcataaa
    23461 caaatcctga gcacgcagca ctgatatcaa aagcgatagc atgagttgct cccaatttcc
    23521 cttgtacttg tgctgctaca gatggtgtcg tgtaatcggg cgacattgtt gctactaaaa
    23581 taaaatccaa atctttaggg tttagatttt tctgttttat caatttttcc gccactaaaa
    23641 tgcataaatc agaagtctcc tgatttgtta cacatcttcg ttcacgaata cccgtccttg
    23701 acgaaatcca ttcatcagag gtatccatca tcttggaaag atcattatta gtaataatct
    23761 tttcaggaag gacgctggct gttgcagtaa tcattccaaa ttgttccatt aaatatcctc
    23821 acttatagtc ttgcaagaag tcgtgcaagt ttttcagtgc atccagcaag gcatgctgtt
    23881 cctccgtagc cattccgtct aagatgttct tgaccatttc acgatgaaaa tgctgatgga
    23941 cccgaaatag taactttcct tttttcgtta gtcccaactt tacaacgcgg cggtcatctt
    24001 cactgcggat acgttcgaca tagccttttt ttactaactt gttaatagca gtggtcaagg
    24061 tcccaacagt aattgatagt tctttggcta cttctgaagt tgtttttttc ttgtacatcc
    24121 cgattgcctc gatcgtgtgc atctctgtga ttgacagatc tttgaattga gattttttca
    24181 gctcagactc ttcgattgtc aaaatatcat tgaagacact aacaagataa tcatttactg
    24241 tttttaaatc tggttccatg ttccaccgtc cactaattag tttgattatc aaatcttttg
    24301 atgttcaaac tatatcttaa cttttttcaa aatgcaacct taaaagatca tttttttact
    24361 atatgagctt tttttaagat tttactcatt taaaacaact gataaatcag cattta
//
LOCUS       DADVXV010000037        24259 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.038, whole genome shotgun sequence.
ACCESSION   DADVXV010000037 DADVXV010000000
VERSION     DADVXV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.038"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(44..1339)
                     /gene="purB"
                     /locus_tag="KB969_001425"
     CDS             complement(44..1339)
                     /gene="purB"
                     /locus_tag="KB969_001425"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBB6869418.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1352..2476)
                     /gene="purK"
                     /locus_tag="KB969_001426"
     CDS             complement(1352..2476)
                     /gene="purK"
                     /locus_tag="KB969_001426"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBB6869419.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2469..2957)
                     /gene="purE"
                     /locus_tag="KB969_001427"
     CDS             complement(2469..2957)
                     /gene="purE"
                     /locus_tag="KB969_001427"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBB6869420.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3373..4680)
                     /locus_tag="KB969_001428"
     CDS             complement(3373..4680)
                     /locus_tag="KB969_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBB6869421.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4683..5264)
                     /locus_tag="KB969_001429"
     CDS             complement(4683..5264)
                     /locus_tag="KB969_001429"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBB6869422.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5380..5477)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5836..7128)
                     /locus_tag="KB969_001430"
     CDS             complement(5836..7128)
                     /locus_tag="KB969_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6869423.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7125..7748)
                     /locus_tag="KB969_001431"
     CDS             complement(7125..7748)
                     /locus_tag="KB969_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869424.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7751..8587)
                     /locus_tag="KB969_001432"
     CDS             complement(7751..8587)
                     /locus_tag="KB969_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6869425.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8604..9491)
                     /locus_tag="KB969_001433"
     CDS             complement(8604..9491)
                     /locus_tag="KB969_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6869426.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9507..10790)
                     /locus_tag="KB969_001434"
     CDS             complement(9507..10790)
                     /locus_tag="KB969_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6869427.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11473..12156)
                     /locus_tag="KB969_001435"
     CDS             complement(11473..12156)
                     /locus_tag="KB969_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBB6869428.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12174..12791)
                     /locus_tag="KB969_001436"
     CDS             complement(12174..12791)
                     /locus_tag="KB969_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBB6869429.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12801..13625)
                     /locus_tag="KB969_001437"
     CDS             complement(12801..13625)
                     /locus_tag="KB969_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBB6869430.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13618..14178)
                     /locus_tag="KB969_001438"
     CDS             complement(13618..14178)
                     /locus_tag="KB969_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869431.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14352..15308
                     /locus_tag="KB969_001439"
     CDS             14352..15308
                     /locus_tag="KB969_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6869432.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15613..16569)
                     /locus_tag="KB969_001440"
     CDS             complement(15613..16569)
                     /locus_tag="KB969_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBB6869433.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16673..17275
                     /locus_tag="KB969_001441"
     CDS             16673..17275
                     /locus_tag="KB969_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6869434.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17363..18862)
                     /locus_tag="KB969_001442"
     CDS             complement(17363..18862)
                     /locus_tag="KB969_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBB6869435.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18878..19402)
                     /locus_tag="KB969_001443"
     CDS             complement(18878..19402)
                     /locus_tag="KB969_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBB6869436.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19700..20449
                     /locus_tag="KB969_001444"
     CDS             19700..20449
                     /locus_tag="KB969_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6869437.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20440..21225
                     /locus_tag="KB969_001445"
     CDS             20440..21225
                     /locus_tag="KB969_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBB6869438.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21194..21910
                     /locus_tag="KB969_001446"
     CDS             21194..21910
                     /locus_tag="KB969_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBB6869439.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22012..23046)
                     /locus_tag="KB969_001447"
     CDS             complement(22012..23046)
                     /locus_tag="KB969_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBB6869440.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(23050..24108)
                     /locus_tag="KB969_001448"
     CDS             complement(23050..24108)
                     /locus_tag="KB969_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBB6869441.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7624 t
ORIGIN      
        1 ttttgctatt ctattttaat tgaattttgc aactcactct tctttattcc aaacctactc
       61 gtttgaatat cacgtcaacg tttttcaaat gatgatgata atcaaaggca tcgtctattt
      121 cttctttaga taataccgat gtgatggttg gatcttcttc taacagcggg cggaactgca
      181 cttggttgtc ccaagcgtac gcagtttttg gctgaacaag atcataagct tcttctcttg
      241 tcattccctt atcgatcaat ttcagcataa cgcgctggct ataaatcaaa ccaaatgttg
      301 cagacatatt ccgcttcatg ttttcaggaa agaccgttag atttttaacg atattgccaa
      361 aacgatttaa catgtaattc aataaaatcg tggtatcagg caagatgatt cgttctgctg
      421 aagaatgaga aatatctctt tcatgccata atgtgacatt ttcataggca gtgaccatgt
      481 gtccgcgcac cactctggct agaccagcca tattttctga accgatcgga ttccttttgt
      541 gcggcatagc agaagaacct ttttgacctt tcgcaaaaaa ttcttctact tcacgtgttt
      601 cggatttttg caatccgcgt atctctgttg caaaacgttc aatacttgta gcaataagcg
      661 ccatcgctga gaaatattca gcatgtagat cccgagggag aacttgagta gagatttctt
      721 gtggacggat ccccaattgt ttacatacat actcttcaat aaatggcggg atatttgcga
      781 acgttcccac tgctcctgag atttttcctg cttctactcc ttttgccgca tgttcaaatc
      841 gttcgatgtt ccgtttcatt tctgaatacc atgtggcaag tttcaatcca aaagtagttg
      901 gttcagcatg gacaccgtgt gtccgaccca tcatcactgt atatttgtgt tcttttgctt
      961 tttcgccaat gatttccgta aaacgtttca agtcttcccg taaaatatca tttgcttgct
     1021 tgatgagata gccataagca gtatctacga catccgtact tgttagacca taatggaccc
     1081 attttctttc ttctcccaat gtttcagaaa ccgctcgtgt aaacgcaacg acatcatggc
     1141 gtgttaattt ttcgatttcc aagatccgat cgatatcaaa tgatgcatgc tcacgaattt
     1201 ttttcacatc ttcttgcggg atttcaccaa gttctgccca agcttcatct gctaaaatct
     1261 cgacttcgag ccacgcacgg tatttgttct cttccgtcca gatattcccc atttcagggc
     1321 gtgtataacg ttctaacatg ttttttctcc tctaatccca aatattcgtt tgtttgattt
     1381 cttccagcgt ttgctggatg tcttctgtca agatagtgat atgtcccatc ttgcgacctt
     1441 tttttgcttg tttttttcca tagaaatgga attgccagtc tggcttattc tcaatcaagc
     1501 gatagctttc cagcagttgt tctcccaaaa cattgaccat tactgcattg cttatcaaac
     1561 gtactttttc tcctaatggc caaccacaaa tacctcgaat atgggcatcg aactgactca
     1621 tagaacaagc ttcaatagaa taatgtccag aattgtgagg acgaggagct aattcattca
     1681 catatagccc gcctgttttt gttaaaaaca tttctacccc taaaacacct gaaaggctca
     1741 ctgcttctgc aatcacacgg gcaatacgct cagcctcctc gatcacatcc tgatcaatcg
     1801 cggctggagc aatcgtttca tgaagaatat tgttgtggtg gatgttttcc acgaccggaa
     1861 aagtcgtgaa atctccttga ccatttcctg ccaccatgat cgaaatctct ttttcaaacg
     1921 ggatccatgc ttctaaaaca caggttcctt ctcttaaaag gtccatggca ggagctagat
     1981 ccgcccgact tttcaaaaca tactgcccct tgccatcata gccgcctcga gtggttttca
     2041 aaacacaagg atagccgatc ccgtcaatcg catcttggat atccgtcgga ctgacgatcg
     2101 ttgcataagg agcaatcacg atgttattcg tttccaaaaa agatttttct aacaggcggt
     2161 cttgcgtaat cgcaagcaag tctgtccctt gaggaataaa tgacatgggt aaaatcgcat
     2221 ttaacgcctc tacactgacg ttttcgaatt cataggtaat gacatctgtt cttctggcaa
     2281 gctctttcag cgcaaaggtg tcatcataga cactttcaat gtgccaatct gcaacttgtg
     2341 cggctggaca atcgctcaca ggatccagca cacctacttt aaagcccatt tcttttgcac
     2401 taatcgccat catacgacct aattgaccgc caccgacgat cccgatcgtt gaaccaggca
     2461 acaaaggttt aaccaagttg atcactactt tctataacag ttttagccaa cattgaacgt
     2521 ctttcagcca atttagcctc caattctaaa tcatacatgg aaagcatctg tatcgcaagt
     2581 agtccagcat taattgctcc cgcttttccg attgctgtag tagctacagg tactcctcca
     2641 ggcatttgga caatcgaaag aagcgaatcc aaaccattta atgttcgtga ttggaccggt
     2701 acaccgataa ccggcaaagt tgtttttgat gcgaccatac ccggcagatg cgcggctccc
     2761 cctgctcctg caataatgat tttgattcct ttttttcgag cgttttgtgc atattcaaac
     2821 atcaaatctg gggttcgatg agcagaaacg accttttttt cataagacac accgaattca
     2881 tccaatattt gacatgcttc tttcattgtt tcccaatctg aagtactccc cataatcaca
     2941 gagatttttg ctgtcattgt ttttcctccc agtttttcta cattcatatt ttaacaatca
     3001 ctttttttga tgtcaaagaa atttcgaatg ttaacaaaga aaaacatttt attgttcgtg
     3061 tttattaaag ataaaaaaaa ggaatgtgac aaaagttagg tcacattcct ttttatggat
     3121 aaacggtgtt ctcctgccaa ctcctcggtc acaaggaaca atattcaaca aacatgagaa
     3181 gctttttttt gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttc
     3241 cttcaacggt gttcaatcag ctgaccctcg gtattagctc aaacaaacgg caaaatacga
     3301 ggaactattt ttccgtttgt ttctctaaca atcaggtcaa aacgctgatt tcacaacctt
     3361 tcttttgctc tattacttct tgaaggcttc ttccaatatt tcttcatctt ttttcaatcc
     3421 attaaagatc aaattcaata tgatagccgt aatgctactc attacgatgc catttccagt
     3481 gaacatttgc aatgtttgcg gcatttgact gaataatgtc ggcgtaacat tgaaacccag
     3541 cccaaatcca acagaaacag caacaatcaa tagattttta tcattgctga aatcaacttc
     3601 caacagcata cggattcctt ggactgccac catcccgaac atgactaaca ttcctccacc
     3661 aagtaccggc tcagggatga tttgtgctaa cgcaccgatt ttagggaata atcctaaaac
     3721 aatcaagaag aatgcagaga aatagatggg ttttcttgtt ttgattcccg aaagttgaac
     3781 caatccgaca ttttgagaaa agccagtata agggaatgta ttgaaaatac cgcctaagat
     3841 aacggcaagt ccttctgcac gatatccctt tttcaattct tcttctccaa catttttccc
     3901 agtaatgtca ccaagtgcaa aatatacacc tgttgattct accatgctga ccatggaaat
     3961 gatgatcatt agtaaaatcg accatacgtc gaaagttggt ttaccaaaat aaaagggttg
     4021 tggaacatgg aacaacggcg catctccaat cgcgctcaga tcaatcattc ccatgaaagc
     4081 agctaagatg cttcctccga ctaaaccaat caataccgcg attgaacgaa tgaacccttt
     4141 tgccagcatt tgcacgccta caattaggag aatcgtcaca aatgcaagta gcagatttgt
     4201 tttgtcacca aaatcagctg ctgttgcatt acctccaccc attttctcga ttgctacagg
     4261 aatcaaagtc aaaccaataa cggtgataac cgttcctgtt actataggag ggaatagttt
     4321 tttaatttta gaaaagacac cagaaactaa cacaacaaag atcccagaag cgataataga
     4381 tccgtagata gctcctactc cttcattggt tccgatcaag atcagtggag ctactgcttg
     4441 gatcgcacat cctaaaacga caggcaagcc aattccgaaa aatcggttaa ctgtcaattg
     4501 caataatgtc gctaatccac acataaagat atcaattgaa atcaaataag tcatctgttc
     4561 ttgattaaag cctagtcctg taccgatcaa aagaggcacc gctactgctc ctgcatacat
     4621 cgctagcaga tgctgcagcc ctaaaaccgc agcttttcca ttttgtgttt ctttttccac
     4681 gattatgcgt cctcctcaag aaactcaact tgtccattcg tcaaggaagc aatacgcgca
     4741 agagaaacga ctctcaatcc catttcttca agtaactgac gtccatcttg gaaagacttt
     4801 tcgatgacga tcccgattcc ttctacttgc gctccagctt gctggcataa ttcgatcaat
     4861 ccttttgccg cttgtccgtt tgccaagaaa tcgtcgataa tcaatacttt gtcttctgaa
     4921 gataaaaatt tacgagaaat agaaatcgta cttgtcactt gtttcgtaaa agaataaaca
     4981 gaagctgtca ataattcttc atccatcgtc aaactttttg cttttctagc gaagatcatt
     5041 ggaacatcta attctcttgc agcaaataaa gctggtgcga tcccagaagc ttcaatggtc
     5101 acaactttcg tgattccttg ttctttaaat acttctgcaa accgttttcc catttgttcc
     5161 atcaatacag ggtctacttg gtgagtgacg aagctgtcga cttttaatac gccctcgcct
     5221 aatatacgtc cgtctttttg aatacgttca actaattctt tcactttatt tgctccttta
     5281 tcatttatta ataccgaaat aaccgctttt gtgcaaaaac ctactatgtt tctgttaaag
     5341 aaaaacaccc tccactttat cataagaaaa gaagggtgaa atagccaatc ttttacttat
     5401 agtccagcat ttacggtact ggctagaaac tgtcatccat attatgacga tatataagta
     5461 ggtatgtaaa actaataata gtgtaaattc attttcttgc aactgttttg cacgtgaagg
     5521 cagtttgcca tatttgaata aaaaatgttg tttcaaatat tgaaaacagt ctaacactac
     5581 tttctgaaac tgacaacgtg gtttacttat ttttttgtaa aatctaatga tttttaatgc
     5641 attattcctt tttgttcggg tttaaatagt tatttttatt ttctcctatc taaaaaagca
     5701 gcccacataa aaagaaggca tgacaaaaag catgtcatag cccctttttc cgaataaata
     5761 gtgttcaaaa gacagcctat cggcaataag gcaagatttt ataaactacg ggaagtaatt
     5821 tccgtaaatc tattcttatt cttttaagct gacaagctcg tcaatcacta ctgcttttcc
     5881 tgaagcaata gaatgatttg ctgcgattcc tgtcaaaatc gacaaaatac catctacgtg
     5941 agttgctgcc cgattccacg gatcttcttc tttttcttca ccaaatagat catctaataa
     6001 acgcggatct cctccgccat gtccgcccgc ttcttgttcg acgattacct catatggctc
     6061 accgaacatc ggatagacat ggatggactg aagaacggct gctccttcat cctttttatc
     6121 tccacctgca ttgatgtaag acttttcgat cactttcatt tcgatccgtc ctttgctgcc
     6181 attgaaagaa acattgaatc cttcccacgg catatacgcg tttagcgaat acgtcaaaat
     6241 cgcaccagtt tcatatttga ccgttacgcc tagtgtatct tcaatagaga tatcatcgga
     6301 aaatacactg cggtcacgaa tatatccact gtctttttct gcttctaaat acatttctcg
     6361 caattcctca ttggctgaca ggtctatagc aaatggatca gctttagcta gttcgcttcc
     6421 atagcatcga ctgtaaaata tttctactcc gcgtttctcc gcattatgca tcccataaaa
     6481 gtttaatcca ccgaatgcaa ataccttttg gggacggctg ttcaaccaaa aattcactag
     6541 atcaaaatga tgggtagatt tatgaacaag aagcccgccg ctattgtgct tatttcgatg
     6601 ccatcttctg aaataatctg ccccgtgttg cgtatttaac agccattcga agtggataga
     6661 aaacacatca ccaatcacat cactttctat cagttccttt atcttcgtgt gatacggtgc
     6721 ataacgataa ttaaaagtga ctcgcaggct tcttcccgtc tgtttttgga ccgttattat
     6781 ttcttgagct ttttcctcat cgatagtcag aggtttttcg caaataacat catatccttt
     6841 tttcattgca cgaatgatat aatcatgatg cgttcgatct actgacgtaa taatgacttc
     6901 agccggccgt acgtcatcca gtagttgctc aaattgtgat ggcatacatg tctttacttt
     6961 tttctgtcca tacttgttca caagtatccg atttgcataa tccatccttg tttgagatac
     7021 atcacaaaaa ccgactagtt cacaagtttg atgatacgta gaggcaattg cctcataaaa
     7081 aaaacgcgct ctcccaccaa gtccgacttg tacatatttt ttcttcattt aaagtcattc
     7141 tccttttctt ttaagcaaaa tactgtgaca aatggcagcc ctggatacag taatgcagtg
     7201 agtaaaaaat catgctgtat acaccagaac agtccataca aaaggcataa ataccacaga
     7261 aaccccttga cgttttttga caacagccag atattccttt tgatcaaata aacaagacta
     7321 tctgctttat cttctttgca gatatcaatt agcgtactaa aaaaactatg ggatacaaaa
     7381 agcaacagac acaatagaaa aggaatcaga taccaagctc caatctttcc cactaataaa
     7441 taccaatcaa ctgcaaaaat aatgacaaac agctgaaaca acgtaatgat gaaacacatc
     7501 cgtttgattt ttcctttcct ccaacatacc tttttttctg ccaagtaatg gacagataga
     7561 taataagaag gatacatcat caaaaaataa atcagataga caacacgagc agacagcact
     7621 aatcctaaag tgaacaaaca tcctagaact aaagcgaaaa gagcattact gataagactg
     7681 gttaaaaaaa tccgacagac atagtagttg agcttgtaaa gaaacatctc ttctattggc
     7741 tttttcatat tcagcccttc agaccgcttg tactgatccc ctggacaaga tatttattga
     7801 agaataagaa aatcagaaaa accggtagca gcgacaacgt agacatcgca aacatactcg
     7861 cgtaagtcgt actagatcca gcgtctgcaa ataatttgat ggcaatcgat accgtgtaag
     7921 atctcggctt gtttaaataa atcaatggtc ccatgaagtc gtcccatttc caataaaact
     7981 ggatgatgat cgtcgtgatg atcgaaggtt tcagcaaagg aaaaataatt ttggtaaaga
     8041 cactatactt gctgcatccg tcaataatcg ctgattcatc taactctttg gggatgctga
     8101 ccatgaattg catgatctgg taaatgaaaa atgcttgtcc aaaaaaatgt ggtaaaatca
     8161 gcggcacata cgtcccaacc aaattcagcc gattgtaaat aataaactgc ggaatcaaaa
     8221 tcacttgtgc aggaatcatc atcgttacta acatgacgac gaaccagaat ctttttcctt
     8281 tgaaatcgat tctcgataat gcgtaagcaa tacaagtcga gctcagaact gtccctatcg
     8341 tcgaaactgc agagatgaca aacgaattcc taaagaaagt aaaaaatgaa attccagcaa
     8401 accccgccca tccttttgcg taattttccc attgaaaagt ctctggaatc aaattcagcg
     8461 aaccactcat aatctcttga tccgttttaa aagaacctgc gatcatccat aagaccggat
     8521 aaatcatgac tagacctaat agcaaaataa aaccgtattg aaaccatttc gttactgtat
     8581 tattcatttc ttcctcctct cattcacaca acgacccatt tttttgatga tttgaaaatc
     8641 agaaaggtga cagctcccat aatcaacagc atgatccacg aaatagcact agcatacccc
     8701 atagaattaa aagaaaaagc ttggttatac acataaagag cataaaagtt cgtggcatca
     8761 ttcggaccac cttgggtaat gataaatgcc tgcgtaaaag tcataaacgc cgcgattgtc
     8821 tgcataacca agttatacaa aatgatcggc gaaagaagag gtaacgtgat cttgtaaaac
     8881 gtctgccatt tgttcgctcc atcgatctct gccgcttcat aatacgagcc tgggatctct
     8941 ttgatacctg cagcaaagat gatcattgcc gaaccgaatt gccaagcaga catcaaaaca
     9001 agagggatca tgaccagttt ttgatcgcta aaccaggaaa gcgcaggtgc gcctaatcgt
     9061 tccaggaaaa tattcactaa cccgttttta gaaaacaact cccgccaaac tagagcgata
     9121 gaaatactgc caccgatcaa actaggcaca taatacaaag aacgaaagaa agtcgttcct
     9181 ttgatattcc tcgttaaaag ataagcaatc aatagaccaa agatcagttt cacaggtaca
     9241 gatgcaaata catagagaaa agtgactcgg atggagttca aaaaacgggc atcactcagc
     9301 atctttatat aattatccaa gccgatccat gagactggat ttcccaaacg ataatcggtg
     9361 aacgaataat aaagtgacaa gatcatcggt atcactgtta tcaatagaaa tcctaggatg
     9421 aatggagaag caaatacgta accgaccaca ttgtcttgat ccaagaaccg ttttagtttt
     9481 tcttttttca tgccttcctc ctgctgctat cctagaatgt ttgacgcaaa ctcataaaga
     9541 ctctctgctg cttcttctgc tgttacttct tcataaatga ctttttcaac taaaagattg
     9601 tattggtctt gaatttccgg attcaaagca ctatcaaaga cattcacttc gccgttgtcc
     9661 atatcggaaa tcatttctaa ataatcaaat gtcgcttgca aagttgcatc atctgcacga
     9721 gcgagctgtt ctcgaatatt cgacatgatt ggtacaccac gttctccttt taaaatttca
     9781 ttggcttctt cactgttttg aaagaaatca ataaacttag cagcttcttc tttatgggct
     9841 gagctttttg ccatactcag catttgcgaa gaacgtaaag ggataccaga ttctccatct
     9901 gcttttctgc gaggtggatt aatcaactga atctccatat cttcaggagc ccctgacaat
     9961 atttctgtca actggttact tgatagaaac accattgccg cttctctatc cctaaccgcc
    10021 tgaaaagaca gatccgtcgt acttgcagct ccaccacctg gttctggatg ggcccctttg
    10081 tctaccagat ttttacgcag ctggaaaaaa tctgttagat agtctggatt ttcaaatccc
    10141 aagctgttag atagatcttc ccgattataa aaattcaatc ctttctcaac ttgtggtatt
    10201 tgaataatac agccagctat aaaatcttcg aatcttgaaa tagcatagat tcctaattct
    10261 tcagtgattt gatagctgat ttgttcaaat tcatcccatg tccaatttga agctggttca
    10321 gggatattta attgttcaaa tatattttta ttgtaagcaa tcgcaaacga attcaccccg
    10381 ttagacagtc caactaattg cccgtcgtaa gtcgtcgttg ctaaatagga ttcatctgca
    10441 ttagaaatat caattatccc ttgctccaca tattcatcta atggttcaat ctgattgatg
    10501 tattgaggaa attgattgtt cagttggaaa atgtcccaga tatcatctga tgctgctagt
    10561 gtacctaatt ttgtgtaata tccttcataa tcataaaatt cataatcgat cgtcacatgg
    10621 ggattttttt cttcataaag ctcgattact tttactgttg catcgtgtcg gacttgcgaa
    10681 ccccaccaag ccatgttcag cgtgattttt ttgtcatctt cttgcccaca agccgtcaag
    10741 aagaataaca taacacttaa agctaagatg attctcattc ttttcttcat tctctgcacc
    10801 tctacttcca ttgttatttt tcaatatact gtatttttat acagaacata tttattaaac
    10861 gatctttttc aaggggaata aaaaccaaga cttgccttat cgttctgcct aggatgaaca
    10921 actcaatact ttcaagaaaa attagatagt gctgattctt ctttcatcgc taaaaacact
    10981 tcttgcttca atgatgggag gataattacg caaagaaaaa aggatatcag acaactgccc
    11041 aatatccttg acatagctaa ataagcatgc ttcttcgtgt gcgctcttcc ctaaaaaaca
    11101 gaaaaataac tagtaattct gtatgaaatt aggtacaata tacacgtcga tgcacaagca
    11161 ttgactatgg caacttgatt ggtcagttcc cgctgacttt tcaagccccg acaatttagc
    11221 tgctactaaa ttgtcgggtg ccttttttag tttttattcg tttttcattc tatagaaagc
    11281 gcttcaataa atcaagacat ttttttgtta gaatgctaat aataacaaaa ggttttaact
    11341 cttcttatgt acattacagg taaaaaaaca aaaaaatttc tctttttttt gaattctgaa
    11401 caaatagtac tggagtacaa aagacgagga agagccacta tctgctcttc ctcgtctttt
    11461 gattctcacc tgttattcat gattcttttt ctcagtttcc cgatattttt ccattttacg
    11521 actaaaaagc tctccgctac ttggtggcgt atatgtgatg gcatttgctc ctgcttgaat
    11581 ggtctcagca atactttctt ccgttggacc acctgtcgca atgataggaa gttcaggata
    11641 ttttttacga aaatggcgta ctgcttctgc agtttcttta cctgcactga tattgataat
    11701 cgaaatacca gctgctaact tttcatctat ttctgtatat ttcgacgtta ccgtactgat
    11761 aactggaata tcaactactc gacaaacttc ttttactgtc tctaaaggcg taggaccgtt
    11821 caaaacgacc cctaacgaac cttgcgcttc tgcgaacatg ctcatgtagg aagaacgagc
    11881 accttgtgtc aaaccaccac ctacaccgga gaaaactgga atgtcagctg cctcaataat
    11941 gcttttagta atcgctggat gaggtgtaaa aggatacaca gcaattactg cattcgcatt
    12001 tgtattacgt atgatcgcaa tatccgtagt aaagatgatc gaacggatca attttccaaa
    12061 tatcttgatc ccgcttgctt ctaaaatgat ttccggtact cttacgatat cttttctcaa
    12121 ttccgtcatg atttctggcg taaattgttc tgccatcagc cacttctcct ttgctatctc
    12181 cggtcatact gattcaattg atacgtctcg atgacctgga tgattttttg cgcataaccg
    12241 gggtctgtcg cataacctgc atcttgcaat gcttgtgcgg cttcctgata gttggtggcc
    12301 gtaatcactt tttcatacag cgcaggattc caatctactc cttggacgaa cagttgtgta
    12361 tggtcatcca tggactgttc ccatgaatca tacactttga agtctccttg gatagttatc
    12421 cattcttcgt taacaaattc ctttgtttcc aggcttactt tcttctgatc cccataagcc
    12481 ttgatcccga aaagattatt gtatttgcta gccaaggtac tttttcccca atttgattct
    12541 aatatagctt gtcctaaaat gatactagga agcactccat aaccatcttg tagttcttgg
    12601 gcatgcggaa caagccgttc aataaattgc tgatgggatt gcgcttcatt ttcttgctga
    12661 ttatcagtaa aaggagaaga cagattcttc aaggaaaaaa caaaggctaa gagtatcact
    12721 gctacaccgg caaccactgc tggccaacgg atattcttgc gcttttgctt tttccacttt
    12781 tttttcgcca tgatcaattc ctacttttca tttaattcat tcagatattc ttctagcgtc
    12841 aattggtgtt tggtgatata ctcagcgttt tctttaccga cataacgtaa gtgccaaggt
    12901 tcatatgtga tcttagttat atcttcgtgt ccttttggat aacgaacgat aaatccatac
    12961 tgcgcagcat tatctgcgat ccatttagct ccaggctgat ctccgtaact tgcatccaat
    13021 acagtagaag gataactgtt gtaccagttt tgatcgacga catcgactgc cagacctgtg
    13081 tggtgttcgc tgtatcctgg ctccgtaatc gtttctttag taatctttgt cgcctcctct
    13141 tctgatacac cttgacgact catcacatct tggacatttt gttcgaaaac ttgttgttgg
    13201 gatgatacag accggtaagc tgagaccatc actaatggaa atccagctgc ttcagcagcc
    13261 ttggcaaatg cttcatattc tggagcaatg cgtttgtcga tcaagtatcc gttacttaat
    13321 gatgccaatt gagtagactc atcaatttct ttttctaatt tgtgatctgg accaaccaaa
    13381 actagcttcc aatcgtctgt tttaacatct ggcaattgtt tggacgtacg atcttttgtt
    13441 tctttgtcct ttaccttgct gctggttgtt tgactgttct tttctttact agcagttgtt
    13501 ttggtgcttg ttcgttcgac tgcttgattg ccggcttgaa catgcgaatc atcatcgcta
    13561 aaaataacat agcccattgc tgcgatcata atcacaactg ctccaaatcc taaaaattta
    13621 ttcacttgaa aaatcctttc gttgttcttc acgttcccca ttcgcctcat gaacgtaagt
    13681 ttcttccaga ttttcattca cccaatcgag aagttcgatt ttttctcctt cgatctgttt
    13741 ttgaacatct gctggcagac gaaaattcaa aatatcatca tagccccatt catcatattg
    13801 aatacttact ttcaagtcaa ggtatctacc agcctgctga ttatttttca aagggatcag
    13861 ctcgactttt gctgctttgc tgctaagcca tttttgcgcg atgcgtgttt tgatttgctt
    13921 gtactctgca acggcaacgt ttcgtttttc gggaaaaata atcgtttgac gcaaaatctt
    13981 ttgcgttagc atccattcat aatcagtgaa aagatttttt actttctgca tcgcttcaga
    14041 tggcagattt ttctcgccat ctttccattt ttgccattgt tctggactga tcagcaagta
    14101 ttcatctaaa aaattttttt cagtttcaaa ctgttctaat aatacactca taataagatc
    14161 aatatatact tgatgcacgt ttatcccctc cttttaacta ttctacttaa gttttgatca
    14221 aaaagcacct cttaaatcgc tgctttcatt ttttttaatg tttcaagtcc tctcctcttt
    14281 attcttcgtg atttttgtta taataataga cagacaagaa actcaatcca actatgaagg
    14341 agcgttttca gatgaaaaaa tatcaatggg gaatcgttgg tcttggtacc atcgcacatg
    14401 agtttgccga aagcttcaat caagagacga gcgaactaac agcagttgct tccagaactt
    14461 cagaaaaagc ggaaaacttc gctcaccgtt acaatattcc aaaagcttac ggaagctatc
    14521 aagaaatgtt agacgatgct gaaatcgaca tcgtgtacat tgctgtacca aatagacagc
    14581 atatcgacca tatcttggca gcattggaag caggcaaaca cgttctatgt gaaaaagcca
    14641 tcacgatgaa taaaaaagaa ctggctgacg ctatgcgctt agcagaagaa aagaatttga
    14701 tcttagcaga agcgatgaca atcttcaaca tgccacttta tcagcagtta cgctcaataa
    14761 tggatacagg aaaactgggg gctttaaaaa tgatccaagc acctttcggc agttacaaag
    14821 aaccagaccc taaaaaccgg ttcttcaatc cagaattagc tggaggagct ctgttggata
    14881 tcggtacgta tgctgtatct ttcgctcgtt tctttttgag ctctcaacct gaagtagttg
    14941 cctctacaat ggttcctttt gaaacaggcg tggacgaaca atccgtcact atcttgcgta
    15001 acaaagaaaa tgaacttgct gctgtcagct tgacttttca ggcaaaaatg ccaaaagtcg
    15061 gtatcgttgc ctttgagaac ggttatgtga cgattgctga ttacccgcgt gctgatcgtg
    15121 cggagatctt atttacagat ggtacaaagg aattcatcga aagcgggaat acatctgaag
    15181 caatgaatta cgaaataaag aatatggtac acatgattga aggtgacttg cccaatcgct
    15241 ctctcttctt gacaaaagat gtcatcgaaa tcttggatca aatgcaagtt ctatggaaaa
    15301 atatgtaatt ttaaaaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    15361 acaaaaatag ctcctcctat ttttcgtttg gctggactta ttaccgcaga ggaaagcttt
    15421 tgaacaccgt ttaagaaaga ggttgtgagc ctaccgttca gctccgagtc acaaggagca
    15481 atttcaaaaa acagcttctc atgtttgttg aatattgtga cttgtgaccg aggagttgac
    15541 aggagaacac cgtttaaaga agaggttgtg aaatcagctt tttgacctga atattagctg
    15601 aattcacaac ctctattttt ggattttttg ttgggagaat tctgccttga tttcaataaa
    15661 acttttaaaa gactgcaaaa actggaacaa ttctgctcga tcctcgaatt cagggcgact
    15721 agtcggcaga ggcatttgcc gatacaatac ataaacttct tcaatacgtg ttaaaatttg
    15781 tctgccatca tttgactctg aaaatgtttc tgcagtataa atcaataaac catagatatg
    15841 ttttccataa taagctggtt gctggattct ctctagattt tccagcatgt ctttaatcac
    15901 attggcctgt gctcttctca tagagaagta agtttcgtag tatagcggct gtctgagcca
    15961 gtagttttct tgatgttctc tggcatcttc ttggctttcg cgaatgaatg tcagtaaatg
    16021 ttcgcatttg atctgcacat cttctttatt ttctgataaa agaaattctg ccatttgtct
    16081 caaaatattt cgaaattctt tttcgatctg tatttggttt tccttcagct gcttcgtacg
    16141 atctggcatg taaacatttg caagcaaagc aaatactaat ccaatcgcca ttaatcccgc
    16201 ttcattgccg atcagctgcc aagacatgtt ttcctccact aaataatgag tgaccaaaac
    16261 cgaatttact actatccctt cggttaattt gaagcgagag gcaagcggga tgaacaggaa
    16321 taaaaaaaga ctgaagccaa aaatagtata cccaacagca aaaaaactga acagtgctgt
    16381 tgccgtagct aatataaagg ctgcgattcg attcatgccc gtacgcaatg tagagcgctt
    16441 ggtatttcct acacttaata atgcaatgat ccctgcagct ggccaataca acagcgataa
    16501 gctacccgct gtgaccatcg aaaagaagac actgatcact gttttgactg ttcgcattcc
    16561 tatacgcatt tacttccccc ttttttattt taattatact tgaataatga aaaactagct
    16621 atcagacaaa agtttaggta tgatagtaaa aagaccaaaa aggagaatct ctatgcaatt
    16681 tggccgtttt cgactaggta tgcgtacgat caaaagtgcc ttagctgttt ttttatgtat
    16741 cttgtttttt catttgactc aacgaggaat cccgatgatt gctgcattat ctgctgtttt
    16801 ttctttgcgt caggacttga ctacaaccgt ttcttttgga aagtctagga tcatcggcaa
    16861 tacattaggt ggtacattag ctatcattta tttttttgtc aaaagctatt ttcacaatga
    16921 ttttttggta gaattgatct tgcttcctat tctagttatt attgtgatcg tcgtgtcaga
    16981 tggtattaac aataattccg gtatcatttc cgcaatagct acgttgttgc tgattgcgtt
    17041 gagcatccct caaggcgaat ccgctttgta tgctatccaa cgtgtactag atacttttat
    17101 agggacattc attgcaatcg gtatcaattt ctttcttcgt cctcctgaaa cagaaaagaa
    17161 ggaagaacta tcagaagatt tggtcgaact ccaaaagaaa gaacgattgc taagaacaaa
    17221 tttacaagag atagaagcta agatccaaaa acaaaagaaa aatagcgagg actaattttc
    17281 ttttgcaata aaataaaaaa atggagagaa gaactttaaa aagtcttcct ccatttttga
    17341 ttgaacggtg aagtgtacta ctttattctt ccttcatcga gttttgttct gcctcttttg
    17401 gcgcttcata catatttact tggctagtag tcccacgtgt cgacaaattc tctacgattt
    17461 ccttcaagtc aagtcctgtt gtcgctttta gtgtttcttg agtagaagaa agcaaatttg
    17521 tggcataatt tgtcactcgg ttcgctccac tggtttctcc tgaactgctt cctgtatcga
    17581 caacagagat tttttcgata tttcctagcg gctgtgctgc ttcgcgcatc aattgcggta
    17641 gcatatcgat aaccatactc aagacagctg cttcgccata ttccttgaag gcattggcga
    17701 tcttttgttt tgcttcggct tctgcttttc cttttgctag tgctgcttcg gcttctgctt
    17761 gtccagctaa acgtgtctta ttggcttccg cttctgccag tgcttccaca cggaatcgtt
    17821 ctgcttcggc ttcagtcact tctttgactt tttgagcttg tgcttcttgt tctttagcgt
    17881 accgatcggc atctgctttt ttcttcactt ccgaatcata ttgcttttca cgacgtgtga
    17941 tttctttttc ttccagttcg atttgttttt gacgttctac gattttaatc tgcatttcct
    18001 gttcgattac ttgttgttgt gctcgggcac tttctaaatt gtaggcttgg tctgcttttg
    18061 ctttagcaac atcttgttct tgtttgtagg ttgctaattt cagttctttt tcttttaatg
    18121 attctgcgat ctctgtttgt cgctgtaatt cagctgcttg tgattctttt tctgcttgag
    18181 cttttttgat acgcgtttct tttagagctt ccgcttctgc tatatctgca tctcttttga
    18241 cttgggcgat tcttggtttc cctaaagagt caagataacc gtttttgtct ctgacctctt
    18301 tgatagtgaa agaaacgatg atcaacccca tttttgcaag gtctacagaa gcgacttctt
    18361 gtacgctttg actgaactta tcgcgatttt gatagatttc ttctacagtc atagaaccaa
    18421 gaatcgagcg caagtgtcct tctaatactt ctcttgcttc attttccagt tcttctcttg
    18481 tcttgcctaa aaactgttct gctgctgtag caatctcttc tacagatgaa ccgattttga
    18541 tgatcgaagt accatcacac atcaccggta cgccttgttc cgtatacact tcaggggtgg
    18601 agacgtccaa tttactcgat aatagactga tccgattcga acgttgaaaa actggcaaga
    18661 cgaatgcgcc acctccacgc acaattttga ttttgttatt gctttcatca atgtgcacat
    18721 ttttgcttcc taaataactt ccactgatga tcaacgcttc atccggtttt gctgtctggt
    18781 acttcgctac aaagacgatc agcaacatca gtaaaatcaa agctgcgatt gcgatcgcga
    18841 taaaaacaac tggtatttcc atttaacaca cgctccttta agcttttatc atgctttcat
    18901 aaggcatgac ataacagatt ctttccttga tctcaatgat caatactttc gttccccgct
    18961 cagctgtctg ttcttggggg ctgtaaaaac aagctggacg actaatggaa ccggtaacac
    19021 ttttcaactg aatttctccc atacctcgta cagggatcgg tgtgatcaca acagctactt
    19081 gtccttccag agttttttca gaagacgaca tcgttgattc ggcatgtttc atcggcatca
    19141 atatatagaa attaagcaaa aataccaaca ctatcgatat gcctccacta gcaataaata
    19201 aaaataaaga tgattgatct gttaaacgct cacctagaaa accaaataag cttgtgaaag
    19261 ttaaccaagg gataataagc atcggatcaa gcgggccatc aaaatcgaat acatctccaa
    19321 aaataatcaa taggactgcc aatcctgcac aaatcagcaa tgtataccaa taaatcgtct
    19381 caagtgcgat tccccctatc atatacacgc ctccttccat ttctacgtct atcataccaa
    19441 tgtttgaaaa ttctgtatag cttcttttac cgactcagtg gtgtttttta taggaaggtt
    19501 gtgtttatcg ttgacaattt gttaaatttt tgttttcatg ttaaaatttt cacaataaat
    19561 tctttcgagg tagcctatgt ttcctttttt taagaaaaaa ccattaaagc tccagaacac
    19621 gatcatcctt gtcgtttgtt tctccacatt cgtttctttg attgtttctg ccatattgat
    19681 caggaatttt attctttcga tgaaccgatc tagtgtgtca gataaaatct ctagcattgc
    19741 taaaatcgtt gccaatgata aactcatcca aaaaaagctg cagactggtg acccgacaca
    19801 tgcgattcaa ggaataacaa atgaaatcat gattgcatcg aatttagatt ttatcgttgt
    19861 catggaccct gaaggcattc gatattctca cgcagaccca agttacatcg gtcttccttt
    19921 ctcaagtcat gaagatgtga aaaaagtgat tggaggacaa gaatttttct ctgaaaaaga
    19981 aggaatgtta gggttcggct tccgctattt cgtccctatt tattatgatc aagagattat
    20041 tggtgcagtt tgtgttggct taacaaacaa cacgattgac aatcaagtca aagatggaca
    20101 aaaaatgatt gttttttcat tgattattgg acttagcgta ggcatcatag gcgccgtttt
    20161 tcttgcccaa aaaatgaaaa aagtactgct tggacttgaa ccacaagaaa tagcagaaca
    20221 gttaagtgaa aaaacgatta tcgaaaatga agtagatgaa ggaatcttag ccatctcttc
    20281 tgataaaact atcctcttga tcaatacacc tgcaaaaaac attttctacc aaacagagca
    20341 gctattggat ttcgaagtag gaaaaaaatc agtgataatc tatatgacgt tttgtttaaa
    20401 gagacgattg agcatcaaac gaccgttcgg actcaatcca tgtatttaaa tgggatagaa
    20461 actatttcta gcgttacacc tctttttagc aatgaccgtt ttttaggagc agtcgcaact
    20521 ttacgaaatc gatcagaagt aatgaaatta atggaggagc ttggggggac gaaacaatat
    20581 ataaactcca tgagagctca aacccatgaa ttcatgaata aacttcatgt catttctggt
    20641 ttgattgatt tgaagaagta tgaagaagtc acccatttta tccagcagct aaatcaaaat
    20701 tataaaaaag agattggcca agtctcaagt ctgatcaaag tacctgcaat tgccggtttt
    20761 ttattaggca aaataaacga agccaaagaa caatctgttg aaatgctgtt agaaagcgat
    20821 tcttttatcc ctaaaatgga gatggatgac tccatccatt cacttttgca agtgttaggg
    20881 aacttacttg ataatgcaaa agaagccgtg ctacaaaaac atgaaagaaa cggacaggtc
    20941 cggattcatt taaactatga cacagaagct gaagtattca tcgtgaccgt ctgcgatgac
    21001 ggtgtcggga tatcagaaga aatctcagaa aaaatattta cgctaggttt ttcgacgaag
    21061 ggaatcaatc gtgggtttgg attgaatctc atccattcaa tcgtcaaacg ccacggtgga
    21121 tttttagaat tttccaaaca aacaaatggc ggtacaatcg tctatctaga attaccaaaa
    21181 aaggaagatc aaaatgatga caaatgtcct gataatcgaa gatgatccaa tggttgcaga
    21241 attgaatcgt acttttgtgg aaagcatccc taatatgaac gtaatcgaaa gtttcagaaa
    21301 tgtagaagaa ggaaaaaaat atttcagaca aaaaaacgca gatctgctgc tgcttgatgt
    21361 atacatgcct ggcgaaagtg gtatccattt tttatcttgg cttagacagc aaggaaatga
    21421 tatcccagtg attttgatca ctgctgcaga tgatatcgaa accataaaga atgtgatccg
    21481 ctacggtgcc ttagattatt tgatcaaacc gttcactttg caacgttttc agctggcgat
    21541 cgaaaagtat cttgctttct ctcagacaat ccaaacgact gaaaaagccg atcagaaatt
    21601 gatcgatcaa gtattcaacc acaccactcc cattcacgaa ataccatcat tcatcgattt
    21661 gcctaaaggt ctgtcaaaac tgactttaaa aaaaataagt gcatttattc taaaagaaga
    21721 tactattttt tcaacaaaag aactggctca aaaaagctca ctgtcacgta tatccgtcaa
    21781 gaaatatttg aattttttag tagaacaaga tatattgaac gaaagaatca aatatttgga
    21841 aatcggccgg ccgctaacct gttatgaatt gacaaagaat gggcggaaaa agctcacaga
    21901 ttactgttga gtcatcgaat tatcccatac aaaatagtcc aagtatacag aagtaacaac
    21961 tgtttacttg gactattttt aaacatttta ttgacgaata tccatgtttt cttatcttaa
    22021 ttgacgggct ttaggaagag atacctcatt tttcgttttt ccagtttcta ttatttcacg
    22081 aaagttctcg aaacttgtcg aaatcatatt tgataatgcc tcatctgtat ttgaacctac
    22141 atgcggggtt acaagaactc tagggtacat ttctactaat tgctggatag cagggtctgg
    22201 aatcgtctcc catggcttga aggatcggaa aaaaacctct gtttcatttg caaaaacatc
    22261 ggttgcaaaa ccagctaaat gattgctttt caaagctctt aaaatagctt cattatcttg
    22321 aagctctcca cgggctgtat taatcaagat gctacctttt ttcatttgag ctaaaaatcc
    22381 ttcattgatc atttgatcgt tttcacctgg gatatgaggt acatgaatac tgacaatatc
    22441 gcttttggct aataactctt caagcgagtg gaacgtcaat acttttttag cagcttctgt
    22501 ctgatgaata tcgtagccga tcactttggc tcctagtccc ttaaacaaaa cagcttccgt
    22561 caaccctatc ctgcctgttc ctatgatccc tactgtgcaa tttctgattt cacgactaaa
    22621 catttgctca tccactcgaa aatctttgaa agatgttcgg atcgtcgtat acgcagtatt
    22681 tctcaaaagc atcatggcaa aagtcaaaga taactctgct atcgcatttg gcgaatacga
    22741 tggtacacgg gctactgtca taccaaaatc agctgccgct tgtagatcga tatgattgac
    22801 tcccacagtc cgtgtaaaaa cataacgaat cccatattcc tgcatttttg caagattggt
    22861 ctcatctgct atacaatttc ccctcaacaa tacagcatca tggtcctttg ctgacacgat
    22921 attgtcatgt gtcaacagtt cttcataaag actgagatca taatggtaaa tattcaattt
    22981 ttcaaaaaaa tctatctcgt tcggacgaac accgtaacat gcgattctca tactttcttc
    23041 ctccatttct tatgaaaata aacctatgcc atgaatcatt tgtaatacaa cgatccatac
    23101 aggtgtcagt accacagcaa aaatagttga cagtaaggat gcattggagg ctaaaagtgc
    23161 ctccctatca aaactgatag cataggctgc tgccactgtt gcagctggtg tagccatcat
    23221 gataacgatt gttgccagtg cttcaaaatt gactggtaga atattcgttg ccgtcaaaac
    23281 tgctagaatc acgatattca atgcaggtac aaataccact ttgactagac tgtaatacca
    23341 tgaagttttt tcagatgcag cttttttgaa gcttacttca cctaatgttg cgccgattgc
    23401 tagccacgcc aatggtgaac ttaaaccagc taaataatcc atcggctgaa atagccacgg
    23461 tgcagtctgg tcaattcgca aaaacgctac ttggcttatc tctccttctg cacctgtaac
    23521 tgacacttgt ggcagatacc cttggaacag ccaaatgaaa aggccggcaa aagtagcgat
    23581 aatgattgga ttgacgaaca tcgctttgat atttttagct tccatcttca agccactcat
    23641 ttttatgtat ccataagaat acaaaaagat tcggtagcca atattgaaaa ttgaggaata
    23701 catcacgccg acaggaccat aaatcgcact gacgataggc gttccgaaaa aggtcgtaga
    23761 accaaagatc gtcaggacac gcaacgttgt ttgcttatcc cctttatagc ttaagaaaaa
    23821 aggttttgaa actagaataa gaataatata aataactaat ccccaaatca agacattgat
    23881 tccttgcatc agtaattctg tattgatatc ttgcatgaaa gctcgaaatg ccagtgctgg
    23941 caaagccact gttaagacga ctttcgatag aatttttcca acagattcag aaaaaatccc
    24001 cttttttcta caaacaaacc ctaataatat aataaaaact gttgaagtga ttgcactgac
    24061 aatcgacata tctgtcaaag tcgatcgaaa aatgtcaaat aagttcatct ttctcctcct
    24121 aattatgttc atttattcac aataaaaaaa gcttttattt tgctaatacg tattaacatt
    24181 tttaatttta tctttacatt gttacttatt gaacaatagg aaattaaaga aacttttgaa
    24241 acttatgtaa agtgatttt
//
LOCUS       DADVXV010000038        24127 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.039, whole genome shotgun sequence.
ACCESSION   DADVXV010000038 DADVXV010000000
VERSION     DADVXV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24127
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.039"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(541..1566)
                     /locus_tag="KB969_001449"
     CDS             complement(541..1566)
                     /locus_tag="KB969_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6869442.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1841..3526
                     /locus_tag="KB969_001450"
     CDS             1841..3526
                     /locus_tag="KB969_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBB6869443.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3540..4823
                     /locus_tag="KB969_001451"
     CDS             3540..4823
                     /locus_tag="KB969_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBB6869444.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4893..5762
                     /locus_tag="KB969_001452"
     CDS             4893..5762
                     /locus_tag="KB969_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6869445.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5759..6595
                     /locus_tag="KB969_001453"
     CDS             5759..6595
                     /locus_tag="KB969_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6869446.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6621..7688
                     /locus_tag="KB969_001454"
     CDS             6621..7688
                     /locus_tag="KB969_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBB6869447.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7685..8512
                     /locus_tag="KB969_001455"
     CDS             7685..8512
                     /locus_tag="KB969_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBB6869448.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8557..9582
                     /locus_tag="KB969_001456"
     CDS             8557..9582
                     /locus_tag="KB969_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6869449.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9579..11762
                     /locus_tag="KB969_001457"
     CDS             9579..11762
                     /locus_tag="KB969_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBB6869450.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11762..12892
                     /locus_tag="KB969_001458"
     CDS             11762..12892
                     /locus_tag="KB969_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6869451.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            12889..13566
                     /gene="pgmB"
                     /locus_tag="KB969_001459"
     CDS             12889..13566
                     /gene="pgmB"
                     /locus_tag="KB969_001459"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBB6869452.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13650..14177
                     /gene="msrA"
                     /locus_tag="KB969_001460"
     CDS             13650..14177
                     /gene="msrA"
                     /locus_tag="KB969_001460"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6869453.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14378..15064)
                     /locus_tag="KB969_001461"
     CDS             complement(14378..15064)
                     /locus_tag="KB969_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBB6869454.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15144..16682
                     /locus_tag="KB969_001462"
     CDS             15144..16682
                     /locus_tag="KB969_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBB6869455.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16802..17269
                     /locus_tag="KB969_001463"
     CDS             16802..17269
                     /locus_tag="KB969_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBB6869456.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            17788..18231
                     /gene="rplM"
                     /locus_tag="KB969_001464"
     CDS             17788..18231
                     /gene="rplM"
                     /locus_tag="KB969_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBB6869457.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            18247..18639
                     /gene="rpsI"
                     /locus_tag="KB969_001465"
     CDS             18247..18639
                     /gene="rpsI"
                     /locus_tag="KB969_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBB6869458.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(18727..19953)
                     /locus_tag="KB969_001466"
     CDS             complement(18727..19953)
                     /locus_tag="KB969_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6869459.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(20025..20183)
                     /locus_tag="KB969_001467"
     CDS             complement(20025..20183)
                     /locus_tag="KB969_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869460.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            20875..21594
                     /locus_tag="KB969_001468"
     CDS             20875..21594
                     /locus_tag="KB969_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6869461.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            21596..22438
                     /locus_tag="KB969_001469"
     CDS             21596..22438
                     /locus_tag="KB969_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6869462.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            22435..23385
                     /locus_tag="KB969_001470"
     CDS             22435..23385
                     /locus_tag="KB969_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6869463.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            23400..23633
                     /locus_tag="KB969_001471"
     CDS             23400..23633
                     /locus_tag="KB969_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBB6869464.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            23964..>24127
                     /locus_tag="KB969_001472"
     CDS             23964..>24127
                     /locus_tag="KB969_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6869465.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINAL"
BASE COUNT         7923 a         4134 c         4951 g         7119 t
ORIGIN      
        1 gtctaaaata atttgtctaa ctagaagaaa agtgggaaag gatcttaaca acatcggttc
       61 gtatccaatt aaggtatcgg aacgatcatc ttccaagaga agtcaatcaa caaaagtaaa
      121 gatagatcat tttttgaatg caaaataaat tgatgggaag atagagcggt tatttttaat
      181 attttgctag ctattattga ataattcctc gaataaaaca aaaccagtag acatgtctgt
      241 tattctattt atgttttaga gataagtatc cccaaataac atggattgaa ataagggtaa
      301 atgtgtttaa aaaaacgaac tataaaaact tatacacaac gtggttaaaa atagtttttt
      361 cttccctgtg gaaaaaatag tttaacacaa acattatagt tatccacagc tatctaaaac
      421 agatggaaaa taagaaaaat tcgctaaaat accgggaggg ggtaacgagg gatgagtgat
      481 tgaaaaaaga acagagtaac tgacttatcc tcagtgtttc tgttctttta taattctgtt
      541 ctacatttct tgttgttgga tcgaatctgt gagagtaatc tcggttgaaa gaatgattct
      601 tttttcttca gggtattggt ggtggattag ttggaataaa agttctgtgg ctttgattcc
      661 taactgattt gtcggaatgt ctatccgagt caactgtggc gaaaataggg aggacaataa
      721 gggatcactg aatcctgcga tcgaaagatc atcaggtatc tgctttccag attgttctgc
      781 cactttgtaa atactcaatg attttaatgc atcggtagaa aaaatcgcag ttggtctttc
      841 tcgtagcttc attaaatcat tcattgctgc catgctatct tctaagcgaa agccgccgtc
      901 tataatccat tcattacgga tatctaggtg gtgatcaaat aagcattgac ggtaaccatt
      961 gagacgatca ttggatacat aaacttctgt cggagcatgg agacagccga tatgacggtg
     1021 tccattcttg atcagtgttt ccaccaaatc gtaactatcc tggaaattat ccgtgtccac
     1081 tgagtagatg ttcgtgtagt cgtttccgac ttttccgatt accacaatag gaatattgta
     1141 ttgatccaat tcaaaaagaa gtgtttcatc catcgtagag cttaaaataa taattcctcg
     1201 gatcattttt tcttggatct ttttcgcgca tttttctagc tcttcttctg gtgtttttgc
     1261 cgtttgtaga atcaagtcga agttattttg ttcagaaacg gcagaaatgg attgaataac
     1321 atctgaaaaa aaaggattgc cataggtcgt atgagaagta cgatgagata atgctagaat
     1381 cgcgtcaaaa ccatttcctg acagtcctct tgcaattttg ctcggttcat aattcaattc
     1441 tttgattgct tgaagtacac ttgcttttgc tttatcagag atatttggct ggttatttaa
     1501 tactctggag acagttgatt ttgagacatt agcttttttc gcaatgtcat aaatagtagg
     1561 tttcaatttt atatgcacct cctttttggg agcgttttag aataattcca tagtacaata
     1621 gacattcttt tttgtctatg attttgaaaa tttaggaata gcttgcatga tcatgagaga
     1681 ccatattttt ttaagaagct attaattatt gatacataag ctttcttatt tgtatttttg
     1741 tgtatatcaa aattatttaa aaaaatgcta ttgacagtaa gcgttttcca taatatgatc
     1801 aaatcgttgg gaacgctccc aaaaaagaaa ggggaatccg atgtatacaa aacttttaca
     1861 agcgatttat cgcgactcag atttgtctga gaaaaccgcc tctatgattg aacaaaaagt
     1921 cagtgtttat cagcagaaga aaggccaggc aggcaaactg cattgggacg aagaagatat
     1981 tttcttgatt acttatgggg atcaattttt tgaagagcag caaccaactt tgcgtacatt
     2041 taagaaattt tatcaaaagt atttggcaga tacatttaga gttgtacatt tcttgccatt
     2101 tttcccatat acatctgatg atggtttctc cgttgtaaat tatcaggcaa tcaacgaccg
     2161 tttgggcaca tgggaagata tagaagaaat gagaagcgaa acacggttaa tgttcgactt
     2221 tgtctgcaat catatgtctg ccgaaagtac ttggtttcag gaatatttaa acttgaatga
     2281 tacgtacaaa gattttttta ttgatttgcc actggataca gatacaagca gcgtgactag
     2341 accaaggacc agcccgttac ttacaacgtt cattgacaaa aacgggaaag aaaaacacgt
     2401 atggacgact tttagcgaag atcaagtaga cttgaatttt aaaaatccag aagttttatt
     2461 gaaaatgatc gatattcttt tgttttactt agaaaaaggc gcttcattta ttcgcttgga
     2521 cgctgtggga tttttatgga aagaactagg aacttcttgt atacacctgc cagaaacgca
     2581 taaaatcatc caattattcc gtgcaatcgc tgatgaagca gctccaggaa cggtattgat
     2641 cactgagaca aatgtgccac acaaagataa tatcagttat tttgggaatg gcgagaatga
     2701 agcacagatg gtctatcagt tttcgctacc acctttgacc cttcaagcga ttcgttcggg
     2761 taatacaagt aagttgaaag aatggttaaa aaccatcgat ttcgcatcga aaaaaacaac
     2821 tttttttaat tttttagcct cccatgacgg tatcggattg aatccggtac gaggtattct
     2881 gccggaaaaa acgatccttg aattagtgga acagctgaag aaagagggta cccgagtaaa
     2941 ctacaagaaa aacccagatg gaacgaccag tccatatgag ataaacgcta cgtatctaga
     3001 tgcgttaagt tctccaacag atacgacgga atggagaagc aaacgctttt tagctgctca
     3061 ttcatttttg gtaacgttac caggcgtgcc ggcaatttat attcaaagtg tgctgggaag
     3121 tcgaaatgat tacaaaggcg tagaaaaaac aggagagaat cgaaaaatca atcggcaaaa
     3181 atttttgtta gcagatattg agaaagagtt gcagacagat ccattaagaa cagcagtata
     3241 tggtgaattg acccagatgc tatctattcg aaaaaaagaa aaagccttcc atccgaatag
     3301 tttgatttac ttactggact cagcagattc ttttatcagt tttattcgcg aagcgaagga
     3361 agagaaagtc ttagttatcc ataatttttc caatcaatca gcaggttatc ttttaccaaa
     3421 aggagattac ctagacctgt tttctggaca aattatccat tgcagtcaag aacgaaagtt
     3481 gatattccag ccgtatgaat atatgtggct gaaaataata aaataagagg tggaaaaaaa
     3541 tgaaaaaaat tattgttact acctgtctgc tagctactgg atttcttctt actgcttgtg
     3601 gtgaaagtca aagctctaac gaatcacaac agacaacgat tcaattcatg cactcttctg
     3661 tcgaacagga acgattaagt gtgatcaatg aactggttgc tgattttgaa aaagaaaatc
     3721 cagacatcaa aatcaagcaa gtgccggtag aagaatcagc gttcaataca aaaatcgtta
     3781 cgttagctcg ttccggtaaa ttaccagaag taatggaagt cagtcaggat tttgctaaag
     3841 tgatggataa agatgaactg attgatcaga cggcagtcca aaacgttatc gaggaagctg
     3901 gagaagataa ttattatgac ggagccaaaa accttgttcg ttcagaagat ggaaaaagct
     3961 atattgctgc accaattagc ggctgggttc aaggtatttg gtatgacaaa gaaaaattat
     4021 cagaagctgg tttttcagaa ccagaaaatt gggatgatat tttaaaaatt gctcaacatt
     4081 tcacagataa agagaataaa caatatggaa ttgctatgcc tactgctgaa ggaacaatga
     4141 gtgagcaagc gttctctcaa tttgctttgt caaatggagc aaatgttttg gatgatgaag
     4201 gcgaggtaac gatcgatacg gaaaagatga gagaagcatt gtcgttttat caaaacttat
     4261 cccaatacac gatgccaggc tctaatgatg tgacagaaat caaagatgct ttcatgaatg
     4321 gaacagcacc aatggcaatc tattcaactt acattttgcc ttctgtttat gaagcgggga
     4381 actcagaaaa tatcggtttt gctatcccaa cacaaaaaga tcaagctgtc tatggcacag
     4441 tatctggatt gacgatttct tctggtctag acgagaaaca aaaagaggct gctgaagcat
     4501 tcacagcttt cttatctcaa ccgaaaaaca tggaaaagtg ggtcttgatg tctcctggtg
     4561 gtgctcaacc agtgaataaa caagtagtcg aactggatgg ttacaaagaa aatgaagtca
     4621 tcaagtcttt tggcgagctg ccatctgaga ttgctagtgc ttttgatgaa gtacaagtct
     4681 ttggactagt cggggaaaag aatttcacga aaatgggaga tatcacaagc tcaggtgtga
     4741 tcggaaaagc agtgaaccaa gtaactgtcg gaaacgaaga tgtcgatcaa gctttagctg
     4801 acgcacaaaa aaatacgaaa taacaagaag ttctgccaat ggtgttcgaa aaaagtagat
     4861 agctattggc agattatcag ggggaggttt caatgaatcg tccaaggaaa cattctgact
     4921 taaaattagc catgggactt ttagcaccaa gcatgctttt attagctgtt ttagtgctga
     4981 ttccaatgct ttccaatatt cagatcagtt ttttcgatat gccgctgaat cctaactcag
     5041 acgccgtttt tatcggatta agcaattatc ttgaaatttt aagtgatagt gaattttatc
     5101 gttctttagg tttaacagtt gcttacacat tcttagttgt agcaggcagt acagctttag
     5161 gattagccgt agctattttg cttaaccgca agttcagatt taggaaaacg gtgcgttcac
     5221 tgattttatt aagttatgtt acgccatcta tttctttgat ttttgcttgg aaatatatgt
     5281 tcaataatag ttatggaatc gtcaatgatc tgttagtaga taggttgcag cttttcaacg
     5341 aagcaccgct gtggttcgac cagccagttg ctagcttctt tatggtcgtt ttgtttgcta
     5401 tctggagata ctatccgtat gcgtttattt catttttggc tattttgcaa acagtcgaca
     5461 aaacgcttta tgaagcagct gaaatggacg gtgcaaatgc ttggcagaag ttcaagatcg
     5521 tgacactgcc ggcaatcaaa ccagtactag caactgtgat tgttttacga tctatctgga
     5581 tgttctatat gtttacagat gtctatctac tgacgaataa agtcaatatc ttaggcgttt
     5641 atttgtatca gacagccttt gcgttcaatg atcttggaaa agcagcagct atatcgattc
     5701 tattgttcat cattattgca gcggtcgtct tgctctcacg aaagaaggtg gacttgaaat
     5761 gaaaaataaa aagagcagga aaatcttatt ttacgcgacg attttgttgc tattagctgt
     5821 caatttgttt ccatttttga tcatgctgat gacatcattc aaggattcac aagaagcaat
     5881 tgcaacgaca caaactattt ttccgaaaga atggactttt gaacattatc aggatatttt
     5941 caatgctgag atttttccat tcatcatgta tttcaaaaat agtttagtga tctccttgat
     6001 agcctccgta actgcagtag tgattgggat cagcggggca tacgctttgt caaaactacg
     6061 cttcaaagct cgctcgaaaa tcaatgctag cttttacacc gtttatatgt tttccggtat
     6121 tttgatcgtt gttccattat ttaaaatcat ttccggtcta ggtttgtatg ataccaatac
     6181 agcactgatt atcacgatgg tcgttcaaac acttcctact gcgatattca tgctaaaaag
     6241 ttattttgac acgattccga ctgatattga agaagcagca atgatcgatg gtcttagccg
     6301 gatccagatc attattcgga tcattatacc attggctatt tctggaatca tttctgtctt
     6361 cgtttattgc tttatggttt cgtggaatga ttatttattt gcttcgattt tcctgtcgac
     6421 ctccgaaaaa tttactttac caatcggttt gaacacatta ttcagtacac cagactacat
     6481 ttggggacga atgatggccg cttcattggt gaccgcttta ccagtcatca ttatgtatgc
     6541 gttatctgaa cgatttatta aaggtgattt agtcgaaggc ggcgtaaaag gataaaaaga
     6601 aaagaaagag gaaagaaaag atgaaaaaat tagttgcatt agaaccaaga atagccggat
     6661 tcaaagatta cgaagaccgt gagatcgaaa agaacgaagt acgtatccga gtaattttcg
     6721 ctactccaaa accaggaaca gaaattgtcg actttagagg attaagtcca tttatcgatg
     6781 aagaattttc agaagaatgg cgcctattct tgccaagaga agaaggaagc caacgcggtg
     6841 tggtatttgg cgaatttcaa ttaggaaata tgattgtcgg tacgatcgaa gaaacgggca
     6901 gtttggtgac agagtatcaa aaaggagagt tagtctgcac ttatggaccc attcgtgaaa
     6961 cgctgattac aaacggtgtt gataattata aactacgtaa acttgatcgg ttggatcaat
     7021 ggaaaaatgc agtatgttac gatcctgctc aattcgcttt aggtggtatc cgggaagcac
     7081 atgttcgagc aggtgatgct gtagcaatct tcggtttagg cgctatcggg caaattgcga
     7141 ttcaattagc taaaaaagca ggtgctacta ccatcgttgg gatcgatccc atagcgcagc
     7201 gtagagaatt agcagaaaaa tacggtgccg attacacgct agatcctatg aaagcagatg
     7261 tcggttttcg tctaaaggaa ttgacagata aacgtggagt agattcagtt attgaaacga
     7321 gtggcagtgc tgccgcatta caagcttctt taagagggat cggctatggc gggatcattt
     7381 cttatgttgc ctttgctaaa ccttttccag ctgggtttaa tcttggtcgc gaagcacatt
     7441 tcaataatgc aaaaatcgtc tttgctcgag catctagtga accaaaccca gattacccaa
     7501 gatggaaccg taaacgaatc gaggacacat gttgggaatt attgatgaac ggttacttgg
     7561 attgtgaaga aatcattgat ccagttgtgc catttgcaga aagcgcagaa gcttacatgc
     7621 gttatgtaga ccagcaccca gaagaaagta tcaaaatggg cgttcaagtc cgaggaggag
     7681 aacaatgaaa ttcggtacgc aagatcaagc atttttccca agagacattt tagaaaaatt
     7741 tagatttatc aaagactgtg gatttgaaga atacgaaatc gacggtaagt tgttaataga
     7801 aaatatcgac acagtcaaac aggcaatcaa agaaacaggg atcccagtag tgacagcttg
     7861 taacggctac gatgggtgga tcggtgactt tatcgaagaa cggcgtctta atggtgtacg
     7921 tcaaattgct gagattttgc gtgcactaag cgaggttgga ggcaaaggaa tcgttatccc
     7981 agcagcttgg ggaatgttca cttatcgatt accgccgatg gtttcacccc gaagcaaaga
     8041 aggagactat aaagcagtca gcgaatcact tcgttattta gataaagtag ccgaagaaac
     8101 aggtacggtt atttatttgg agcctttgaa ccgataccaa gaccatatga tcaatttgtt
     8161 agcggatgcg cgtcattaca ttgactctaa tcaattgaaa catgtgcaga tcatcgctga
     8221 tttttatcat atgaatattg aagaagatga tatttcaaaa gcattgacta cgcaaaaaga
     8281 gtatgtgggt catatccatt tagcagataa tcatcgctac caaccaggat ctggcgcaat
     8341 tgattttact cgccattttc aaacgctact tcaaaatgag tatgaaggtt atatggtata
     8401 tgaatgtcgt ttgcgaggag aaaatgaagt gaaaatttat caggaatcat tgcaatactt
     8461 gaaaaactgt ctggaaacag cgcgtcattt aaatgattta gagaaagaat agagaaagaa
     8521 taacaataag taaataagca aaggagggag aaataaatga agaaagtagc aatcataggc
     8581 gctggacaag tagcagaaaa agtacatgct gcttattatc aaaaaagatc agatgtctta
     8641 gaattggccg ctgtggttga tccagtcagc cagcgagcag aagacttttg ccgacgtaca
     8701 ggattttctc atgcgtatac atcagttaca caaatgctga atgagatttc tcccgatatc
     8761 gtgagtgtct gtacacccaa tcgctttcac ttcgaacatg tattggctgc cctcgaagct
     8821 aatgcttcag tgatgtgcga gaaaccacca gctatgacag ctgatcaagc aagaaagatg
     8881 gcagagacag ccgataaaaa cgggcagatt ttggcttatg gattccagca tcgtttttct
     8941 gacgaagcaa caatgatcaa gaatcatctt gatgttctcg gggatattta ttacgtagaa
     9001 gcgaatgcgc ttcgtcggtc tggtgttcca ggctggggaa cgtttatcga caaagaactt
     9061 caaggaggcg ggcctttgat cgattatggc attcacatgc ttgatacagc gatgtatatt
     9121 actggatttc ctaaagtaaa aagcgttcgg gcgtacagct tccaaaaaat tggtacgaaa
     9181 aaaaattcag ggaaattcgg gaaatgggat ccaagcaaat tcacagtaga agatgcaatt
     9241 tttggcacac tggaattaga aaacggcaag atcatccaac tgaatacttc gtttgctttg
     9301 aatatcagag aagacaaact gaatgtggct ttttgtggcg atcaggcagg tgctaatctg
     9361 tatccaggcg aactattcga agatgtagat ggaaagctgg tttccttaca aaagaccacg
     9421 ccagttaatg acccacatga actaagtatg gctcattttg tgaatcgggc gctcggtgac
     9481 cagactcaga tgattgcaga tggctggcaa ggatatgtca tccagaatct ggtggaaaat
     9541 ttatatcgtt cggcagaaac aggagaagtt attaccttat gaaagtagaa gaaaaacagt
     9601 ttgatttaga gtatatcaat aagtatgcga gtcagatgac cattggaaat ggattttttg
     9661 gtatcagagg aagccaggag gaagactatc ggaatcaagt aaggggaatg tttgcagctg
     9721 gtgtatataa ccgaccttta ggagcagaat cagccgagtt agtgaatctc ccagatgtca
     9781 tcagatggga aataaaaatc gacggtgaac atttttctct tgagacgatg aaagttcttg
     9841 catacgagcg ggcactagat ttagaaatgg gagagcttaa acgctatgcg ctcattgaaa
     9901 ctgctcaagg aaaaaaagtg gaagtcatta cttgtcgtgt tgctgatcaa aataatctcc
     9961 atcaggcagc cctgaaagtg gtcatcaagc cgttgaccga agactgccaa gtagatgtga
    10021 aaacgggtat cgatggacag caaaccaatt ttggtacaca gcagttggtt gaaaaagaac
    10081 tgcgagtatt tggtgacgat ttgatcagtg catcctacca gacaacagaa agtaaaattg
    10141 atattgggat tgcagctaaa ttcaataaag caggtgtatt ccaagcaaaa aatcgccgga
    10201 tcaccgcttc cttttcagaa aagatcagaa aaaatacgtc ctttacgctg gagaagatca
    10261 tcgtgctctc tacctctctt cagcaaacag acccgtttaa gaaaagtatt gcccaagccc
    10321 agaaaagcgt tagttataca gaaattttag agcagtcgat gtcttattgg acagattttt
    10381 ggcatcagca tcggataacg atccaaggcg attcttcttt cgatcagtta gcgatggact
    10441 tcgctgctta ccatttacag attatgactc cccgcaatga tccaagtgtt agtgtagggg
    10501 cgaagggact aactggcgaa ggttataaag ggcatgtttt ctgggatacg gaaattttta
    10561 tcctgccttt ctttttatat cagtttcctg aagtagcaaa gaatttgctg ctgtaccgtt
    10621 atgatcgatt agaaggcgca cggcaaaaag caagagatta tcactatcaa ggtgcacttt
    10681 tcccatggga aagcgcacac actggtcagg aagagacacc caaatttgct gcattgaata
    10741 tcaaaaccgg aacaagacaa gaagttgctt cagctgccgc agaacatcat atcagtgcag
    10801 accttgctta tgccgttcaa gagtatgtcc aagcaacaga ggatcaatcg tttttagaaa
    10861 caaagggaaa aacgctcatt catgaaacag cagctttttg gctgagcaga gctgtaaaag
    10921 tcgatgatca tttagagata cacagagtca ttggtccaga tgaatacaca gaatatatcg
    10981 acaataatgc atatacgaac tatctggcgc attataatgt ggccttagct gttaaatatc
    11041 aagctggcga tccgcttttt ttgaaagaat gtcaaaattt tttagataag ttatatttgc
    11101 cagtgcctaa caaagaacag ctgattccgc aagatgacac gtatctcagt aagccagtta
    11161 ttgatttgac cacttacaaa gaacgtcctg gcagccagtc tattttactt gattatgccc
    11221 gtagcgaagt aaatgaactc caagtcagca agcaagcaga tcttgtcatg ctgttatact
    11281 tattacctga gtatttttct caaccaatcg tttctaagaa tttgcattac tatgaaaaca
    11341 aaacaatcca cgactcatcg ttgagtaaag cgattcacgc catagaggct tgccgtatcc
    11401 aagaaatgga atgggcgtat catttattcc aagaagcgtg cctgattgat ttaggaccag
    11461 atccgcattc atcagatgac ggaattcatg ctgcttcatt aggagcacta tggctagcag
    11521 ttatatttgg tttttcaggt attacagtaa cgaatggaac tctttctatt tctccaagac
    11581 ttccttcagc atgggaaaaa atttcttttc cttttatttg gaaaaatcac aggttgctat
    11641 ttgttttgac aaaaaaacaa atagtaataa aaaaagagac gaaagaaaca ttacctattt
    11701 ttgtcaatgg agaccaatac cagctggaaa aagaactgat cttggaacgg aggggaaaat
    11761 aatgcgtatt ctgattgcgc cagattcttt caaagaaagt ctgacagcct tagaggcagc
    11821 acaagccatt caatcaggtt ttcaagaagt ttttgttcag gctgaatatg atctgctacc
    11881 tataggcgat ggaggagaag gaacggtttc atcattagca gacagtttaa ggttgaagcg
    11941 gcaaacagca gtcgttacta atgcatttgg caaaaacaaa gaaatccagt acgcttcaga
    12001 cggtcaaact gcgatttttg aaatggcaga aatcgtcgga ttgaaagatg tcccactaaa
    12061 ccaacaacag ccacttaggt tatccacgcg aggagtagga gaactgatac gacaattgtt
    12121 gcaacaaggt gttcgacaca tcatcatcgg cgttggcgga agtagtacca acgatggcgg
    12181 catcggcatg gcagaaggtc taggttatgc tttttacgat caagataatc aaaaagtaga
    12241 agcactggga gaaaatctag gtaaaattgc tacagttgat aaaacgaacg tgcctattga
    12301 gctgattaaa gccaaaatca ctgtcattac tgatgttact aatcttttat gcggaaaaga
    12361 aggcgcttct tttgttttcg gaccacaaaa aggcttgaaa gaaaatgaat tagcagtggc
    12421 tgaccaagcc atgcatgatt tttatatgag atttgcccct caagtaatcg aggcatcggg
    12481 cagtagtgct ggtggtggaa tgggtgcagg actgttagca tttgcttcag ggaaaatagt
    12541 ctctggcatc gactacgtat tggatttact ggagttcgat aaacgggtac agcaagcaga
    12601 cctcgtaatc gtaggcgaag gacgtctaga tggacaaagt ctaaaaggaa aagcgccagt
    12661 tgggattgct agaagagtac cagagggcgt tcctgtgata gctatttgcg gaagtgttgg
    12721 taaaggaagc gaaaaagcag cagatgttgg catttcggcc gtttttccga tccttcctgc
    12781 agctgtgcct ttacaagaag ctttacagca agccactgat aatcttcatc gcacagctaa
    12841 aaacatcgca tctttacttc aagtcgttca ttttcaagga ggtaatcgat gaaaatcaaa
    12901 gcagcactat tcgatttaga tggcgttctt gtagacacag ctcgttatca ttacgaagcg
    12961 tggctggttt tagctaacca gctgtccatt ccattcactg agaaagaaaa cgagcaactg
    13021 aaaggaatat ccagaaccga gtcactagag cgattgctgt catttggaaa aatggaacag
    13081 aaattctcag aaaaagagaa atcagccttt gctgagcaaa aaaacaatct atatcttcaa
    13141 gcgattcaaa aaatggatga aacatccgtt ttgcctggtg caatagctgt tcttgagtac
    13201 ttgaaaaaaa caaacatcaa gatcggattg ggatcagcaa gcaaaaatgc acgcctcatt
    13261 ttagaaaaaa cgaatttgac aagttatttt gatgtcctta ttgacggcac gcaagtatca
    13321 aaagcaaaac ctgatccaga agtttttctc aaaggagcac agcaattgaa tgtaccgcca
    13381 aatgcatgct tggtcattga agattcagaa gctggttgtc aagcagcttt ggctggtaac
    13441 atgcatgtat tgggaatagg tgaaaacata aatcttcctt ctgctgaata tgtgattcct
    13501 gatttaaccg tttttgatca agtacgttcg ttttggcatt tatcagaagc cgtatcacgt
    13561 atataatagt ttccgttttt tctgtcacaa gcaaaacgtt atcctccttt tggaaatcaa
    13621 ggtatgatga gaaaaaaggg ggattttata tgacaaaaaa agcagttttc gcaggcggat
    13681 gcttttggtg tatggtcaaa ccatttgaag agcagccagg gatcatttct gtgacatccg
    13741 gttatactgg cgggcatgta ccaaatccaa cttatgaaca agtaacaaca ggcacaacag
    13801 ggcatacaga agcagtagag atcgaatatg atccagaagt tatttcttat gatcagttgg
    13861 tggaaatcta ttggcagcaa accgatccga ctgacgcatt aggacagttc gctgatcgcg
    13921 gtgattctta tcgtccagtg atctactata atgatgaaga agaacgaaat attgcagagc
    13981 gttcaaaaca agcattgcaa gacagcgggc gattcgataa gccaatcgtg acaaaaatcg
    14041 aaccaagaag cgaattttat cctgcagaag attaccatca ggattattac aagaaaaaca
    14101 agctccatta caatctttat cgagaaggtt ctggacgtgc aggtttcctt cgtcgacatt
    14161 ggggcgtcaa gaaataagaa gccgaaaaag ctacttatgg aacaccgtat atcagaggtt
    14221 gtaaaaccag cattttgagc taatactgag ggtcagctga ttgaacacca tttagtggag
    14281 aggttgtgaa cctgtcgcct agctccaagt cacaaggatt tggtaagaga acactatata
    14341 tcagaggttg tgacaagtcg tttgtcacaa ccttttttca atacctaaga tgaaggacaa
    14401 tcagcaacgc actgctcaaa aaaggaatga aaggcagctt ttccaacttt tttttatgac
    14461 agataaagta aacagaaaaa acggatattc caaacagact agcaagaaac aagatctgaa
    14521 gcaactcttc tagagacaag ccaccactcc aagaaagcat caacagagta tcgccagctc
    14581 cgagatagga ttgaccatag cgaaggcaca caccgcctac gataaacgtt aacagcacac
    14641 tttgccattg gaagacgccg gcctgcaacc aaaaaatcca taaaattgcc caagaacaga
    14701 atagcgtgtg agaatggacc atgaagtaaa ataaatccat caacgaaaat agcaaagccg
    14761 aaagcatcca tatgaacgtc gaaaaatttc ttgcggaaga aaaagtaaag aaccaggcaa
    14821 aaagaccacc acataaggct tctgccaaca aatagtagaa gggcaaccga cacctgcaat
    14881 agcggcagcg aaatcgttgg acgatgatcg agagaatcgg aatcaattca taccaagaaa
    14941 gcgaacgaca gcatttgaca caatgagatc taggataaat aatagagtga cctaacggaa
    15001 tccgctgggc ggttaaacat aaaaatgatc cgatacagca accaatgata aaataaagta
    15061 acacgccatc tccccctttt caaaaccaag atacgcaagc ttaaactaaa tttttgtaca
    15121 tacataaaat ttgaggtgaa aaaatgaacg tttcaatcgg attagatatc ggaaccacac
    15181 aaaccaaagc agttgctttc acagatgaag cccaagaagc agcatccgct tattttcgct
    15241 accctttgat ccaagaaaca caagggatgg cagaacaaga tcaggaattg atctttcaag
    15301 gtgtctgcac cgttataaaa gaagtaatta aacagttgcc ttcagacaca atcattcaat
    15361 ttgtctcctt ctcctctgcg atgcatggcc tgatattgtt ggatgaagag aaaacaccgt
    15421 tatctcgaat gatcacttgg gcagataacc gagcagcgga cgaagcagaa aaactgaaat
    15481 ataccgtgct tggcaaagaa ttttatcggc agactgggac gccgattcat ccaatgacac
    15541 cattgaacaa aatcaagtgg ctgcaaaaca gccaacctga attattcaaa aaaactgctt
    15601 attttgtcgg tatcaaagac tatatctttt atagattgtt tggcgaactg atcagcgact
    15661 acggaacagc ttcaggaact ggatattttg atatccatga attccaatgg gcagaagaag
    15721 tgcttgacta cttgaacatt cgaatagagc aattgccgca agtctttcct tccacctatc
    15781 aagtaacagg tctaccatca aaaacagcag cagaactagg tttgccaaat gatatatcat
    15841 ttgttttggg aggggcagac gggccgcttt ctaatctagg gttaggtgct tttggtgata
    15901 cgatcgccgc tttgaccgta ggaacgagcg gagcacttcg ttttattact actcagcctc
    15961 agttccatcc agaaatggag acgttttgtt atgttctgga tcagaaacat tgggtagtgg
    16021 gaggagcgac tagcaatggt gctggcatct ttgattgggc agggcataca tttttacagg
    16081 aagtcgttca atctgctaaa gaaaaaggag aaaatccata tgatgcactg ctttcggcta
    16141 tcgcttttgt gccagcgggt gccaatggtc tgatttttca tccctattta cttggtgagc
    16201 gagcaccgct ttgggacgca gatgcgtttg gcagttttat cggtttacag cggcaacata
    16261 cagaaaaaga aatgatgaag gcgattctag aagggatctg tctcaacctt tatcggattt
    16321 taaaaggagt ttgccaggaa aatcagctca cagagatccg tgctacaggc gggtttgctc
    16381 aatctccgat ttttcgtcag atgatggctg atgtactggg ttacccgctt gttttcccta
    16441 ctgtcacaga agcatccgca ttaggagctg tgattttagg ctggagaagc atcggaaaga
    16501 tccaaagtat cagtgaagca caggaattga tagaattgaa agagcaagtt ggagtacaag
    16561 aaactgatca taaaaaatat cagaaaatct atccattatt tgtttcgaca caaaagcatt
    16621 tagcacagac ttatcagcaa tttgctcaac tgcgagaaga attagctgat tctgaaaaat
    16681 gattggcttt acggataaaa aagcgaactg aaaatcgttc tcaggtaaat gattttgttg
    16741 tacttttcat tgaaagtcta ctattatttt aagtgtaaga aaatgttagg aggcaagaaa
    16801 gatgaaattc caacaaacca aagaagtatt aaatcaatta gttgcagatc taagccaaat
    16861 gtctgttgtt gttcaccaaa cacattggta catgagagga ccaggtttcc ttacattgca
    16921 cccaatgatg gatgagttca tggatgattt gaacgctcag ttagatgaag tatccgaacg
    16981 cttgatcaca ttagacggtt caccttattc tacattgcgt gaatttgcag ataacacaaa
    17041 aatccctgat gaaattggcc gctgggatcg tactattcca gaacgtttgg aaacacttgt
    17101 tgcaggctat cgttatctag cagatcttta ccaaaaagga atcgaagttt ctggagaaga
    17161 aggcgacgat ccaacacaag atatctttat cgaattcaaa acagccacag aaaaacgtat
    17221 ctggatgatc caagctcatt tgggcaaagc gccagagatc gacgcgtaaa aactgttgtt
    17281 gaacttgacc gaaaaagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa
    17341 acgtcaaaat agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat
    17401 tgaacaccgt ttaccaagag gttgtaagcc tgccgttcag ctccgagtca caagaaacaa
    17461 ttttaaaaaa cagcttctta tgttttatgg atattgtgac ttgtgaccga ggagttggca
    17521 ggagaacacc gtttattcaa aataaggggt tgtgacaaga cttttgtcac agcctctttt
    17581 tgtttttcat tttgacagga aacgaccctt ttatataaaa gaaagaaaag aagtaaagtt
    17641 tcatataaat ttttcaatca agcagaaaaa cgttgacatt gactagatta gcgggtaata
    17701 tgttaaatgg tattgtttgc cccacaaaga gccccggaaa ctcgaagtgt atgtcaaaca
    17761 tcagaactta aattggagga aaataacgtg cgtacaacat atatggccaa accaggcgaa
    17821 gtagaacgta aatggtatgt agtagacgca actgatgttc cattgggacg tctttcaaca
    17881 gttgttgcat ctgtactacg tggtaaaaat aaaccaactt tcacacctca tttggatact
    17941 ggcgatttcg tcatcgtcat caatgcagac aaagtgaaat taacaggtaa aaaagcgact
    18001 gacaaaattt attaccgtca cagcaactac ccaggaggat tgaaatcaat cactgctggc
    18061 gaattgcgtg ctaaaaattc tcgtcgtttg atcgaaactt ctgtaaaagg tatgcttcct
    18121 aaaaacactt taggccgcaa acaatttaca aaattgaacg tatacggtgg agcagaacat
    18181 ccacatgcag cacaacaacc agaagtttta gacatcacaa acttaatcta ataggaggga
    18241 atttcattgg cacaagttca atatatcggc acaggccgtc gtaaaaacgc agttgctcgc
    18301 gtacgtctag taccaggaac tggcaaaatt actgtaaata aaaaagatgt tgaagaatac
    18361 attccacatg ctgacttgcg tgaagtaatc aatcaacctt tcgctgttac tgaaacaaaa
    18421 ggcgcatatg acgtatttgt taacgtaaac ggcggaggat acgctggaca atcaggagct
    18481 atccgtcatg gtatcgctcg tgcattgcta gaagttgatc ctgacttccg tttagctctt
    18541 aaacgtgctg gcttacttac tcgtgacgca cgtatggtcg aacgtaaaaa accaggtctt
    18601 aagaaagcac gtaaagcttc acaattctca aaacgttaat atcctttata tatcaacgtt
    18661 tctggcactt ttcaattatt tggaaagtgc ttcttttgtt tttaagaaca catttaagaa
    18721 cacatatcaa tcacacttat tcaatcctct ctgaaaagct tcaaaaacag ccttatcaac
    18781 tatatctggt gtgttcacat atatctttgt tgtagaaata tctgagtgtg ttaaagcatt
    18841 tgaaatttga ttcatatctg ctccaccttg tctagctata gttgcataag tatgacggag
    18901 tttgtgtgga gataaatgaa ctaagtcagg atgccttctt ttaattgaat tgattcgata
    18961 gtttaggtaa tcggcatgaa caggacaatt tacttctcca gatggtttag tataagtaaa
    19021 gagatactga tctaacgttt gcttaatttt taatttcaac aattgatcag cttgtaccga
    19081 tttccattca cttagcaatg tcattacaac ttctggtact tgaatgacgg tatcttttcg
    19141 accttttgta aacttttttc tttgatattt atctaaagta tgtttaagac ggaccgtttg
    19201 tttttcaaaa tcaatatatt tccattgcaa agcgtaagtc tcactttttc tatcaccaag
    19261 atacagggta atcataaaaa gtgtgtaatc atgaaaagta agtaaatgat tattaaaatc
    19321 atcatttact gcttctatcc aattagtaag ttcttttgat gatagtgctt gcttaccttc
    19381 ttgtattctt ttttcttcta aagcattttt tttaggtgca gtgatacttt gaataatttt
    19441 agtagttcga ttaaattcga tataatttag tatttctgca atatcgaaca tggaacgaac
    19501 atatcctttt atgattttta tatttgcata ttctttcgat tttttggtta attcatctga
    19561 tattatctca gtattgatat ttagataatt cattgcgtat tcaccaaaca taggtaaaat
    19621 atgcaaccga aatatatctt ttgtattact aatggttata tcactaggag gcctgtttga
    19681 tctaattgtt tgacctaatt catatctagg aagccattta gattcgtaaa attttttaaa
    19741 cgttattttt ccttttaatt ctaatgagtt tgcattctcc tctctcaaaa ctttttctat
    19801 tttcttcttc atatcatttt cggctttaat cgccaattgc ctatttggaa atgttttttg
    19861 atacttttct gatgcaattc ctgttatttc tttaaacctt tttggatatc tcagattagt
    19921 tttatatttc ccatttgaaa gctttgtagg caaaatcctc actccttaaa aaaagtaagg
    19981 cagtatattt cactaatttt agtatatgcg gcgagaagaa aatttcaagt tattttaaat
    20041 gtattcataa agtctttaat atcttctacg tcaaagcgaa ctacaccacc aactcttatt
    20101 actgggaaat tatatatacg aatccactta tctagagtat tattatcgat tcctagaaat
    20161 gcacaggttt gttttttatt caggtagact ctggattcta taaaatcatc tcctaaaata
    20221 gtagttatga aatttttgaa ttgctttggg taagcacata ggaatttcac ctctccccag
    20281 tttacggcga gccttacgga agtatcatta tttgctgcta ttgtcatggc attttgtttt
    20341 cccagaacaa aaagaaatct ctaagtattt gtcgctaatc aggtcatggc gtacttgagt
    20401 ttctagctcg aatagcaggg atcgttattc aaaaattgta tttaattgtc aatgatcaaa
    20461 aatagttttt ttcctattca ctattaataa cgataaacat gtataaaaag acacactacg
    20521 aaaaaagtta aatggagttt actgattttc atatttgtat atggaacaga catagtcttg
    20581 aataattttt ataaatgttt tgatgcttat caacttattc aacccgctat ccacttcaag
    20641 tataattttt ccatacgcca ataaagtagt tttaggagca tgttctcatt tgagaacgct
    20701 ccttttttat atattttgaa agctacttac tatacgcgta gtttcaaata gttttgtcat
    20761 tctaatcttc agcaacagaa aaaaatctaa actataaaat ttagggttga ctaaaatata
    20821 atttttgtat accatatgat cgtgataatc attatcattt agaaggagaa agttatgtta
    20881 gaagtgaaaa agcttaatgt ttgttataac gattttttag cattgaacga gatttcttta
    20941 aaaatacaag aaggtgcttt aacaggtatt attggtccaa atggtgctgg aaaatccaca
    21001 ttgcttaaag caatgttaaa tattatccct catcagggag aggtctccat taataatgaa
    21061 gatatcaata aaaaactggt gaagattgca tatgtagagc aaaaagctga tattgatttt
    21121 acttttccaa taaaagtaaa agaatgtgta tctatgggaa catatgccgg aatgaaagtt
    21181 tttcaaagaa ttaaaaatgc agaatggcaa agagtttcaa aggctttgga aaaggtcgat
    21241 atgggaaaat attctaatca tcaaatagga gaattatctg gaggacaatt tcaacgtgta
    21301 cttttagcaa gatgtcttgc tcaaaatgcg gatttcatat ttttagatga accatttgta
    21361 gggatagact tagttagtga acgaataatt atggatacgt taaaaaaatt gaaacatcag
    21421 ggaaaaacag tgctaattgt gcatcatgat ttaagcaagg taaagaagta ttttgataat
    21481 attattcttt tgaatcgaaa tctaattgct cacggaagtg tagaatctgt atttaatgaa
    21541 gaaaatttaa aaaaagccta tggagatact atatttattg gagaggggga ataatatgct
    21601 tcaaaatttt attaatggtc tgtatgactt tcacttttta cagaatgctc taattacatc
    21661 tgtagttata gggattgttt ctggaacagt aggttgtttt attattttaa gaggaatgtc
    21721 tcttatgggt gatgctattt ctcatgctgt tttgccagga gtagcaattt cttatatttt
    21781 aggtattaat ttttttattg gtgcgattgt atttggtcta ttagcttcta tcattattac
    21841 ttttataaaa agcaatagtg taataaaagg agatacagca attggtatta ctttcagttc
    21901 ttttttagca ctaggagtta tccttatagg agttgcaaat agctcaacgg atttatttca
    21961 tattttattt ggaaatattt tagctgtaca agatattgat aagtggatta caattggcgt
    22021 ttcggtttta gtgttggtta tagtagttct attttttaaa gaattattaa tcacttcttt
    22081 tgatccatta atggcaaaag caatagggat gaatgtcagt ttttatcatt atctattgat
    22141 ggttctatta actttagtag cagtaacagc tatgcaaagt gtgggaacta tattaattgt
    22201 tgcaatgtta attacaccag cagctacagc atatttatat gcaaatagct tgaaaactat
    22261 gatatttatt tctgcaacag tcggagcaag ttcatcattg cttggattgt ttattggtta
    22321 tagttttaac atagcagcag gatcaagtat tgttttaaca gcggcattct tatttgtaat
    22381 tagttttcta atctcaccaa aacaaaaatt tttaagaaag aaggagagat cgttatgatg
    22441 agaaaatgga aagcagtact gggaagtctg gggattttga ttgctctttt tatattcggg
    22501 gcatgttcaa taaatagtaa agacaaagat aaagtggctt cgaacgaaaa attaaaagta
    22561 gtagttacta attcgatttt agcagatatt accgaaaata tagcaaaaga taaaattgat
    22621 ttacacagta tcgtacctat tgggaaagat ccccacgaat atgaaccttt gcctgaagat
    22681 gttcaaaaaa cttcaaaagc agatttgatt ttttataacg gtgttaactt ggaaactgga
    22741 ggaaatgctt ggtttacaaa attagttaaa aatgcgaaca aagaggaaaa caaagactat
    22801 tttgcagcaa gtgatggcat agatgttatt tacttagagg gtcagagtga gaaagggaag
    22861 gaagatcctc atgcttggtt aaatttagaa aacggtatta tttacgctaa aaatattgaa
    22921 aaacagttag cggaaaaaga tcctgataat aaaaaattct ataaagaaaa tctagataag
    22981 tatattgaaa aattggattc tctagacaaa gaagctaaat ctaaatttgc ttcaattccg
    23041 aatgataaaa aaatgattgt tacaagtgaa ggatgcttta aatatttctc gaaagcgtat
    23101 aatgtgcctt ctgcttacat ttgggaaatc aacactgaag aagaaggaac accagatcaa
    23161 ataaaacact tagttgaaaa attacgcaca acaaaagttc cctccttatt cgtagaaagc
    23221 agtgtggatg atagaccaat gaaaacagta tcaaaagata ccaatattcc tatctattca
    23281 acgattttta ctgattcaat tgcagaaaaa ggacaagatg gtgatagtta ctatgcgatg
    23341 atgaaatgga acctggataa aattgctgaa ggcctttcga aataatttgg agggtaggta
    23401 tggtacaaat taaaacgact actatactaa tttatttact agcaattcag gaattatcaa
    23461 aaagaaaaaa gaaattaaaa aataatgatt tagcaaaagt tctaagtgtt agtccagcat
    23521 ctgtaagtga gatgctggct aaacttagat atgaggacta tttagatata ggatttcaat
    23581 taactgataa agggaaaaaa tttattgacg attacaaaaa aggttttaag taaaagactt
    23641 tatttttagg gaggataaga aaatggctat tggagtgatt atgataggac ttatcctaat
    23701 agctggatat aattttttta aatctttctc ggattatttt agaaaaggtg aatgatttag
    23761 atgagtctat taattcttgt aggattgctt tttgtatcag ttattctgct ctttctcatt
    23821 agtttagctc taaggaatga gttcagtaat aaacgttaac gattgaaact tcaagtcctg
    23881 tgtaagataa taaagttaat tcatcttatt aggaggaagt acccatagaa accagagatt
    23941 atattataac tcaccaaaag ttaatagaaa gtggactaag ccattttgaa aaagaaggat
    24001 ttcagcaaac taagataagg caactgtgcc tgaccgcagg cgtaactacg ggtgcttttt
    24061 ataaacattt tacttctaag gaagcgttat ttgaagaaat tattcagccg catattaatg
    24121 cgcttat
//
LOCUS       DADVXV010000039        23829 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.040, whole genome shotgun sequence.
ACCESSION   DADVXV010000039 DADVXV010000000
VERSION     DADVXV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.040"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(53..787)
                     /locus_tag="KB969_001473"
     CDS             complement(53..787)
                     /locus_tag="KB969_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBB6869466.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="KB969_001474"
     CDS             1114..1524
                     /locus_tag="KB969_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBB6869467.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="KB969_001475"
     CDS             1517..2218
                     /locus_tag="KB969_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBB6869468.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="KB969_001476"
     CDS             2218..3804
                     /locus_tag="KB969_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869469.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="KB969_001477"
     CDS             3823..4044
                     /locus_tag="KB969_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBB6869470.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="KB969_001478"
     CDS             4041..4802
                     /locus_tag="KB969_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBB6869471.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="KB969_001479"
     CDS             5182..5691
                     /locus_tag="KB969_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBB6869472.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="KB969_001480"
     CDS             complement(5766..6305)
                     /locus_tag="KB969_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBB6869473.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="KB969_001481"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="KB969_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBB6869474.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="KB969_001482"
     CDS             7318..8169
                     /locus_tag="KB969_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBB6869475.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="KB969_001483"
     CDS             8197..8832
                     /locus_tag="KB969_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBB6869476.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="KB969_001484"
     CDS             8852..9625
                     /locus_tag="KB969_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6869477.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="KB969_001485"
     CDS             10033..10830
                     /locus_tag="KB969_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBB6869478.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="KB969_001486"
     CDS             10808..11221
                     /locus_tag="KB969_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBB6869479.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="KB969_001487"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="KB969_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBB6869480.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="KB969_001488"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="KB969_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBB6869481.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="KB969_001489"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="KB969_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBB6869482.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="KB969_001490"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="KB969_001490"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBB6869483.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="KB969_001491"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="KB969_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBB6869484.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="KB969_001492"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="KB969_001492"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBB6869485.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGVFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="KB969_001493"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="KB969_001493"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBB6869486.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="KB969_001494"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="KB969_001494"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBB6869487.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="KB969_001495"
     CDS             21905..22483
                     /locus_tag="KB969_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6869488.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="KB969_001496"
     CDS             22535..23017
                     /locus_tag="KB969_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBB6869489.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="KB969_001497"
     CDS             23134..23508
                     /locus_tag="KB969_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869490.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4286 c         5115 g         6648 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggtat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtttt
//
LOCUS       DADVXV010000040        23729 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.041, whole genome shotgun sequence.
ACCESSION   DADVXV010000040 DADVXV010000000
VERSION     DADVXV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.041"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(102..677)
                     /locus_tag="KB969_001498"
     CDS             complement(102..677)
                     /locus_tag="KB969_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBB6869491.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(682..1656)
                     /locus_tag="KB969_001499"
     CDS             complement(682..1656)
                     /locus_tag="KB969_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBB6869492.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1680..1724)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1939..2907
                     /locus_tag="KB969_001500"
     CDS             1939..2907
                     /locus_tag="KB969_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6869493.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            3004..3297
                     /locus_tag="KB969_001501"
     CDS             3004..3297
                     /locus_tag="KB969_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBB6869494.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3415..3651
                     /gene="secG"
                     /locus_tag="KB969_001502"
     CDS             3415..3651
                     /gene="secG"
                     /locus_tag="KB969_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBB6869495.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3754..4509
                     /locus_tag="KB969_001503"
     CDS             3754..4509
                     /locus_tag="KB969_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6869496.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4512..6869
                     /gene="rnr"
                     /locus_tag="KB969_001504"
     CDS             4512..6869
                     /gene="rnr"
                     /locus_tag="KB969_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBB6869497.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6891..7355
                     /gene="smpB"
                     /locus_tag="KB969_001505"
     CDS             6891..7355
                     /gene="smpB"
                     /locus_tag="KB969_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBB6869498.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7657..8376
                     /gene="atpB"
                     /locus_tag="KB969_001506"
     CDS             7657..8376
                     /gene="atpB"
                     /locus_tag="KB969_001506"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBB6869499.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8429..8644
                     /gene="atpE"
                     /locus_tag="KB969_001507"
     CDS             8429..8644
                     /gene="atpE"
                     /locus_tag="KB969_001507"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBB6869500.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8735..9259
                     /gene="atpF"
                     /locus_tag="KB969_001508"
     CDS             8735..9259
                     /gene="atpF"
                     /locus_tag="KB969_001508"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBB6869501.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9246..9788
                     /locus_tag="KB969_001509"
     CDS             9246..9788
                     /locus_tag="KB969_001509"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBB6869502.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9811..11367
                     /locus_tag="KB969_001510"
     CDS             9811..11367
                     /locus_tag="KB969_001510"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBB6869503.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11381..12283
                     /locus_tag="KB969_001511"
     CDS             11381..12283
                     /locus_tag="KB969_001511"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBB6869504.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12306..13712
                     /gene="atpD"
                     /locus_tag="KB969_001512"
     CDS             12306..13712
                     /gene="atpD"
                     /locus_tag="KB969_001512"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBB6869505.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13726..14148
                     /locus_tag="KB969_001513"
     CDS             13726..14148
                     /locus_tag="KB969_001513"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBB6869506.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14617..14847
                     /locus_tag="KB969_001514"
     CDS             14617..14847
                     /locus_tag="KB969_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBB6869507.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14944..16245
                     /gene="murA"
                     /locus_tag="KB969_001515"
     CDS             14944..16245
                     /gene="murA"
                     /locus_tag="KB969_001515"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBB6869508.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16258..16434
                     /locus_tag="KB969_001516"
     CDS             16258..16434
                     /locus_tag="KB969_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6869509.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16569..16865
                     /gene="yidD"
                     /locus_tag="KB969_001517"
     CDS             16569..16865
                     /gene="yidD"
                     /locus_tag="KB969_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBB6869510.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16929..17396
                     /locus_tag="KB969_001518"
     CDS             16929..17396
                     /locus_tag="KB969_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6869511.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17481..18365
                     /locus_tag="KB969_001519"
     CDS             17481..18365
                     /locus_tag="KB969_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6869512.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18479..18715
                     /locus_tag="KB969_001520"
     CDS             18479..18715
                     /locus_tag="KB969_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBB6869513.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18803..18883
                     /locus_tag="KB969_001521"
     tRNA            18803..18883
                     /locus_tag="KB969_001521"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18837..18839,aa:Tyr,seq:gta)
     gene            18890..18961
                     /locus_tag="KB969_001522"
     tRNA            18890..18961
                     /locus_tag="KB969_001522"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18922..18924,aa:Gln,seq:ttg)
     gene            19087..19257
                     /locus_tag="KB969_001523"
     CDS             19087..19257
                     /locus_tag="KB969_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869514.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            19477..20184
                     /locus_tag="KB969_001524"
     CDS             19477..20184
                     /locus_tag="KB969_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6869515.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20243..20887)
                     /locus_tag="KB969_001525"
     CDS             complement(20243..20887)
                     /locus_tag="KB969_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBB6869516.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            21014..21301
                     /locus_tag="KB969_001526"
     CDS             21014..21301
                     /locus_tag="KB969_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869517.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21409..21729
                     /locus_tag="KB969_001527"
     CDS             21409..21729
                     /locus_tag="KB969_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869518.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            22047..23123
                     /locus_tag="KB969_001528"
     CDS             22047..23123
                     /locus_tag="KB969_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6869519.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23120..23729
                     /locus_tag="KB969_001529"
                     /pseudo
     CDS             23120..23729
                     /locus_tag="KB969_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         7840 a         4142 c         5106 g         6641 t
ORIGIN      
        1 ctgagccaga atgtggttca ttctgactca gatttgattt tgcacaactc atcagtcctt
       61 attgacaaag agccttattt tgctaatcca gctctgttta ttcagcctat ttttcttttt
      121 gaatatatca agcgttgtgg caacatagtg atgactaatg aaacaacgac gatagacaac
      181 aaacgatcaa ggtagtctgt acctgcctgt accaagatca cacttgttgt ctgacttaaa
      241 cctaacccat gtaatagctg aacgatcata ctggatcctg aggaggtgat cccgccaaat
      301 aactgaacgg taatgatcga agaaacgatc gttccaggta ccgacaaaat caaagcgagt
      361 aataacagtt tcaagctgtt tttatctttg ccgagatatc ttggcaaaat caatccagca
      421 agcaagcctg tgagaatttg gattggcgaa taatacagag aaaaaatatc tgtagtcact
      481 ccacttaaaa taccgctgga caatcctgtc agcattccag gtacaggccc aagcaatgca
      541 ccagcaaaaa tcgttccgat agaatcgaga tagattggca aacgaagcca taaagcaatc
      601 gttcctccaa tataattgat cccaatacac aaagccatca ctgtaagtac gcgagttgcc
      661 attttgtttt tattcatttt gttagcccat ctttaacctt tccaaatctt tcataatcgt
      721 ttcttcttgt gcatttaaaa gaacggttaa aaactttcgg aaaaaaagac gagtatctac
      781 ttttgtcata attttactgt tagcaggttt ctgccaaaat tcataacgat caaccaatgt
      841 ttgtccacga cttattcctt gagtttccac agcagtgaag cttttgaaac cttcacagat
      901 ggcctcctcg ataaaataag caacagctaa cggatcattg atgacacatc ctaaaattct
      961 ttcttgtttc cagtggaagt caaaataaaa acgagtgatc gcttttagat actctccctc
     1021 ttcaggattc atttgacagc agtattcgag gatagtcggt gtcaagacga tttctcttgt
     1081 cacatctaac ccaaccattt ctatcgtttg tttgagattc tcgaatacat aagaagctgc
     1141 ttcaggatca caccagtaat tgtattcagc aactggcgaa cagttaccat ggcttttgta
     1201 agttccaccc atcgagacaa aacgttccat atgtttccca atatttgggt tgactttcaa
     1261 agcagaagcg atattggtca aaggacccaa agcaatgact gatgtatttg tcttttcttt
     1321 gaaataatca gccaaaaaat caacggcatg gagaggttct gcctgttttc tcaagatcat
     1381 cgggaaattt gtttccccta aaccatccat accatgagtg tcttgtgcac tgatgaaagg
     1441 ttgcttcaaa ggtttttcca ttccttgata aacaggaatg tctaaacgat cacagcgttc
     1501 caggcatttc agcacattct gcgtacctat atctgcaggg acattcccac aaactacggt
     1561 aatagcaact acttcgatat caggggattt gacagctaat gataaagcta aagtgtcgtc
     1621 gatccctgga tcgcaatcaa taattacttt tcgcattatt tccaatctcc tttctttaga
     1681 gatacttagt tttttattct gggaagtttc cgaaccagtc caagacgagc gtcttgatta
     1741 taatgcacga aattagtata ctggctttta ttgcgaatgt aaatgctctc ttacaagtaa
     1801 atctattgag gagaacttta agtaaatgat acaatgaaaa agaaatggaa tttacgtgtg
     1861 ccgaaaataa agaatcctat ggatcggtac attggataat agatagatta tagtttggca
     1921 gaaagcggcg ggtgtacaat ggttattttt tatttcattc ttattctgat aattataggg
     1981 atcagttacc attttctttc ttatttttat gcaaagaaat tagtaagagc gggagtacag
     2041 agaggatatg actggtatga agacactggt catcgtttga tggaccctgc tgcagtcacg
     2101 tcagtagaaa aaaaacgaca aaaattagaa gaagagtgtg aaagcttttg ggagcaggga
     2161 acacccaaaa caatcaaaag ttatgacggg ttgaaactag ctggtcagat gttcatccat
     2221 ccaaataagc agaataaatg ggtcatttgc gtacatgatt accgaagcac agggaaaaga
     2281 gacatgtctc atataggtaa aagatatgca gagaaaggat tcaacgttct tgtacctgat
     2341 ttacgtgcgc acggagaaag tgaaggagaa atcatcggaa tgggatggct agatcggcta
     2401 gatttaattg cctggatcca actcatctta gatgaacagc cgaatgcgtc cattatttta
     2461 cacggcggat caatgggagc ttctacgatc atgatggcaa gtggtgaaaa acttccatca
     2521 gcggtcaaag gatttatttt agacagcgga tatgtttctg tttatgcaga attccgatat
     2581 atgttaagta aaatcactgt ctttcctaaa aaaatggtca tgagatatgc gaatcattat
     2641 gcccagaaat acgccggtta ctccttaaag caagcatcag ctacgagaca gcttggcagc
     2701 aatcatctgc ctttattagt catccatggt gaaagagatc attttgtccc tacagaagca
     2761 gcgtacacga ttcaaaatgc tacggcaggg gataaagcac tgctgcttgt tccggaagca
     2821 gaacacttgg aagcatcgat gaaagatccg aaaacctatt ggacagtgat tttttcattt
     2881 attgaacaaa gaataacgat gaattaattt tctcttcttt tttgtaagta attcgaggat
     2941 aaataattgt ttatagatca ggagactgct aaaataaggt aggaataaaa aaatatcagt
     3001 tatttgagga gtgcggcata tggaaatcaa agaagaaaaa atcgtcttgc tttattcaat
     3061 gatgaacaac aagagatcgg agaaatgaca tggtcagatg cgggcccaga catcatgatc
     3121 gttgaccata catttgtaga tccagcatat cgtggtcaaa agttagctga aaagctagtg
     3181 tatactggag tagaattagc aagacgagac gggaaaaaga tcattccttt atgcccttat
     3241 gcaaaaaaag agtttgaaaa gaaaccagaa tatcaagacg tcttacgtca gtcataagaa
     3301 taacagctga aagttttgaa ctttcagctg ttattccatt tatatagagt tgtcacggac
     3361 ttttatctat gataaagtta aagagacgat atcttttggg aaggaggctg cgatatgtat
     3421 aatttaattt tgggaatcgt gatcgtttta tcgattgtta tggtcattgc gattatgatg
     3481 cagccaagca agcaaaatag tgcagcgagt gcatttaccg gcggtgcgga tcaactattc
     3541 ggcaaacaaa aagctcgcgg ctttgaagct gtcatgcagc gatcaactgc agttatggga
     3601 gctatctgga tgatcttatt atttgtccta gcatatttat cttcgaagta gttgaataag
     3661 cctctcgcaa aacggcgggc ggcttttttt attgcaaaga gaacgcttaa gaagaagtta
     3721 tgaaagaaac tatggtaaaa tgaggcgaaa gaggtgagac gagtgagaca attaccaaaa
     3781 cccctttatg caaaacatgg aaagcgagcg gttttgctgc ttcacgctta ctcaggaagt
     3841 ccaaacgatg ttcgaatgct cgcacgattt ttggaaaaag cagattatac agtttatgcg
     3901 ccgcttttta aaggacacgg aacaatggag ccatatgata tcttgcaaga aaaagcagaa
     3961 agctggtggg cagacactaa aaaagccatc cattttttac agtctgagca gttttctgat
     4021 attgccgtat taggattatc aatgggcggc atctttgctg tacgagcact agaagaagaa
     4081 tcagtgattg gcggcggttt tttctgttcg cctttgtctc ctgtaaaaac aaacgtgcct
     4141 gaaaactttg aaaaatacgt acgtcaagtg ctgaagacag caggtaaatc agagaaagaa
     4201 atcaatgaaa aagcagttgc ttaccgctcg ttagctgaac aacaattaat ggatatacaa
     4261 gatcaggcag caatcgtaga aagtaggttg tcagatatcc aacagccgat atttttagct
     4321 caagctggga aagatgaaat gatcgaccct aatggcgtat ttgaaactgc acgcaagttg
     4381 agccgtcagc gagtgacact tcaatggtat cctgaaagtg gtcatgtgat tacagttggt
     4441 acagcaagac gcgaattaga aaaagacgtc ttggaatttt tagaaaaatt accttggaat
     4501 gaggaataaa tatgacaaaa gaaacgataa aagagaaaat tctctttttc atggaaagca
     4561 gtcgcaaacg cagtttttct atggaagaaa tcgctgaagg tttagggttc caaaaaagcg
     4621 atgattttaa attactagta caaacgattg ctcaaatgga aagagaacag agtatagttt
     4681 tcaataaaaa aggaaaagtg aaacttcctt taaaaccaat cctgatcgaa ggaacatttc
     4741 gagcaaatga acgaggattt ggatttgtaa cgattgatcc cgaagaagat gacatctata
     4801 tcccaaaaga agcgactggt tttgcaatgg atggagacac cgtagcaatc gatatcatga
     4861 agcgagcaaa tacagatatg gatcgcggag cagaggggaa agtagtcgag attcgagacc
     4921 gggcgactac tcagttagca ggggaattcg ttgcttattc agaagaagaa atacaagaaa
     4981 cagatcttta cggcgttgtt atcccgaaag atagaaagct caaccaattt aaagtatatg
     5041 cagcagcaga gggagttcgt ccagttgacg gaagtattgt gctgatcgaa ctgacccatt
     5101 accctgaaaa agggtatgcg actagtttag aagggataat caagcaagtg attggtcata
     5161 agaatgaccc tggcatggat atcctctcaa ttgtcgtggc taatggtatc cctacgaaat
     5221 ttcctgatga tgtattgtct gaagcagatg aagttccaga tcaaatcagc gaaaaggata
     5281 taactggacg tagagattta agaaatcagc tcattgttac gattgatgga gaagatgcaa
     5341 aagatctaga tgatgcagtt acggttaaaa aattagataa cggtaattat tttcttggag
     5401 tacacattgc agatgtttct tactatgtga cacaaggcag tcaattggac agagaagcat
     5461 atgaaagagg gacaagtgta tatttgactg atcgagtaat tccgatgatc ccgcaacgtt
     5521 tatcgaatgg tatctgttca ctgaatcccc atgttccaag gctgaccatg agttgcgaaa
     5581 tggagattga tccaaatgga caagtagtct ctcatgatat tttcccaagt gtgatccaaa
     5641 caacagaacg gatgacctac acagctgtca atcaaatctt agaagatcaa gacgaagaaa
     5701 cgatgcaacg ctatgctcag ctcgtaccta tgttccaaga aatgggtgaa ttgcaccgaa
     5761 tccttgaaac gatgcgaatc aaacgtggcg cgatttcttt tgaggatcgc gaagcgaaaa
     5821 tccttgttga tgctgaagga cacccaaatg acatccagct aagaagcaga ggaattggtg
     5881 aacgcttgat cgaatctttc atgcttgcgg ccaatgaaac ggtagctgaa cattataata
     5941 aattaaatct gccgtttatt taccgaatcc atgaacagcc aaaagaagaa aaaatgcagc
     6001 gcttctttga ttttgcttca gctttgggca ttctggtccg aggaacgaaa ggaacgatca
     6061 caccaaaaga tttacagcat gtgatcgaag gagtagaaga caaaccagaa gctgcagtta
     6121 tcaatactat gttgctaaga agcatgcaac aagcacgcta ttcagaagac aattttgggc
     6181 attatggctt agcggcagat tactacacac actttacatc tcctattcga cgctatcccg
     6241 atctaatcgt ccatcgtctg atccgttctt acagtgaaga taaaagtgaa agcaatcaaa
     6301 gttcgtgggc tgcggaactt cctgaaattg cagatcatag ttctaagatg gaacgtcgtg
     6361 cagtagaaac agaacgtgaa gtagattcca tgaagaaagc agaattcatg atggacaaag
     6421 tgggagaaga attcgatggg atcatcagct ctgttgtgaa attcggcctg tttatcgaac
     6481 tgccgaatac agtagaggga ttgatccata tcaatgaatt gaaacaggac tacttccatt
     6541 ttgttgaaaa tcatttagct cttgtaggtg aaagaactgg tctgactttt aaaatcggac
     6601 agaaagtgcg agtaaaagta gtcaaagctg atccagatga acgagcagta gattttgaac
     6661 ttgtttccgc agaagaggtt acagcgttgg aacggccaaa aacacgaaat ggaaaatcag
     6721 gaaaacgcga aggaaaacaa gcaggaaaac gcccagaaag aaatggcaag aagaacaaac
     6781 gatatagcga tagtaagcaa acgttcggta agaaaaaagg gaagaagcca ttttacaaag
     6841 gtgttaaaaa gaagaaaaag aaaaaataaa atgagttgga ggaaacagct atgccaaaag
     6901 gcgagggaaa attaattgca caaaacaaga aagctcgcca tgattattcg atcatcgaca
     6961 cgatggaagc agggatggtc ttgcaaggaa ccgagatcaa gtcgatacga aacagccgga
     7021 tcaatctaaa agatggattt attcgcgtcc gcaacggaga agctttcttg cataatgttc
     7081 atatcagtcc ttatgaacaa ggaaatattt ttaatcatga tccgttgcgc acgagaaagt
     7141 tattattaca caaaaaacaa atcatccggc ttgaaaatga attgaaaaat actggaatca
     7201 ctgttgttcc tttaaaagtc tatattcgta acggctatgc caaggtattg attggtctgg
     7261 cgaaagggaa aaaatcttat gataaacggg aagatttgaa acgaaaagat atcgatcgac
     7321 aaattgatcg aacattaaaa aatttctcta gataatttca ttatcctttt tcgcatattc
     7381 ggtgcttttg cttttactta atgataaaat ttgttagcat ttaatctgat aaaacatgat
     7441 tatcataggt tttttcttag atcaggagca ccgtgtataa agaaaaattc gcttcgtttt
     7501 tgactgaaat aaaaaagtgt ctaattttca tgaaaatgtt ttgaattttc tgtttcatgg
     7561 tggtatgata ccgtgtggtt agaaaccgat tggaaaaaac cagatacgca catgaattga
     7621 ttttatgtga atttcgggga aaagaggtga aatggattgg atgaacgctc gctaacgttc
     7681 cacattggac caatttggtt tgatggtaca gtttgtataa tggtgttact gacctgtttg
     7741 attgttttct tcttagctta cttttttaca agaaatctta agttgaaacc aacaggcaaa
     7801 caaaatgcga tagaatgggt cattgatttt agtcgaggaa tcgtaacaga taatctgcct
     7861 agaaaagaat tgagcaattt ccatttgttg gcatttacat tgtttttatt tgtttttgtt
     7921 gcaaacaaca tcggtttagt aacaaaaatc gttttaccta acgaaacaac actttggaaa
     7981 agcccgacag cagacccgtt tgttacttta actttggcat ttataatgat cttacttact
     8041 cacttattcg gggtgaaaaa gttaggcttc aaaggatatt tcgtaaattc gttcttgaaa
     8101 ccctatagtt ttatgtttcc gatgaaactg attgaagaat ttacaaactt attaacactt
     8161 gctttacgtc tttatgggaa tatttatgcg ggggaagttt tgctaacctt gattgcaaaa
     8221 atgatgacaa gcttaggctg gttctcatta ccattagcaa ttccattaga gatggtctgg
     8281 atcgcgttct ccttgtttat tgggagcatc caagcatttg tctttgtcac tttgtcaatg
     8341 gtttatatga gccataagat tgaagtagaa gaataatact cggttaaaaa acaaactact
     8401 atttatctat tttaggagga aaacaattat gaattatatc gcagcagcaa tcgcaatcat
     8461 gggagcagca atcggagccg gttatggtaa cggtcaagtt atctctaaaa caatcgaatc
     8521 aatggctcgc caacctgaaa tgtctggtca attccgtaca acaatgttta tcggggtagc
     8581 tctagttgaa gctgttccta tcttaggggt agttatcgcc ttgattctag tttttgccgt
     8641 ttaattgaat cagtattaag gcagaaacaa catcgtttgt tactgctttt ttacatggaa
     8701 actagaaata ctccaaagaa aggaaggctc gcctatgctg aatcaattgg caattgcaga
     8761 agttggcaat gcgatgttag gtaatatcat cgttgtcagc ggctcatttt tgatactact
     8821 ggctctcttg aagcactttg cttggggacc aatcagcgat attttgaaaa aacgtgaaga
     8881 caagatcgcc aatgatttag attctgcaga acaatctcgc atcaactcag cgaaaatgga
     8941 acaagaacgc gaacaacaat tgttagcctc tcgttctgat gcagctgata tcatcaaaaa
     9001 tgcgaaagaa agtggagaat taagccgcca aaatattttg aaggatgctc aagaagaagc
     9061 agctcgtcta aaaagcaaag cccaagctga tatcactgta gaacgtgatt cagcgctgaa
     9121 ctctgtaaaa gacgacgttg cagaactctc tcttcaaatc gcggaaaaaa tcttgaacaa
     9181 agaattatct ccagaaatgc atgaatcatt aatcaatcaa tacattgaag gtctaggttc
     9241 ttcaaatgaa actagataaa tatacagtag gaagacgtta cgggaaagct ttatttgaac
     9301 tggcgatcga ttcaaatcaa gcagaagaaa tctatcaaga tctcgtaagt ttacgtcaaa
     9361 tctatgaaca agtacctgga ttagggaata tgttaagtga tgttcgtcta gaacctcatg
     9421 aaaaacgaga aatcatggac aagcttgtca gcggttatga tgggatcgtt aaaaactttt
     9481 tagaagttgt ttatgagtat aaccgaatgg atgacctttt gttcatgatc gaagaatatg
     9541 aacgtcgata tgatgaacat caagggttac tattgggaag tgtcacaaca gcagtcccac
     9601 tttcagacga acaacgaata caattagaaa agaatgttgc aaaaacaatg gactatcaat
     9661 cagttgaatt aaaacaaatc gttgattctt ctattattgg tggcgcgatt gttgaagcca
     9721 accatcgagt aatcgacgga agcattcgca cgcaattaga aaaaatgcgt aatcaattaa
     9781 acagatagta caaagaggta ggtgaatcga atggccatca aagcagaaga aattagtgcc
     9841 ttgattaaag aacaaattga aaattatcaa aacgtgcttt cagtcgaaga aatcggtacc
     9901 gtaacttatg taggtgacgg gatcgctcgt gcacatggtt tagaaaacgc gatgagtggt
     9961 gagttgcttg aattttcaaa cggctcatac ggaatggcgc aaaacttaga gtcaaatgat
    10021 gtaggtatca ttatccttgg cgatttcgag tccattcgtg aaggagataa agtaaaacga
    10081 acaggtaaga tcatggaagt tccagttgga gaggccttga tcggtcgggt agtcaatccg
    10141 ctaggtcaac caatcgacgg actaggtgaa atcgttactg acaaagctcg tccagtagaa
    10201 gcgatggcac caggtgttat gcaacgtaaa tctgttaacg aaccaatgca aacagggcta
    10261 aaagcgatcg acgcccttgt gccaatcgga cgcggacaac gtgaattagt catcggtgac
    10321 cgtaaaacag ggaaaacttc tattgcgatc gatacgatca tcaaccaaaa aggtcaagat
    10381 atgatctgta tctatgtagc aatcggacaa aaagattcta cagttcgtac acaagttgaa
    10441 acattgaaaa aatatggcgc aatggattac acaatcgttg tgaatgccgg tgcgtctcaa
    10501 ccagcaccat tgctttatat cgcaccatat gctggtactg caatgggtga agaattcatg
    10561 tacaacggta aacatgtatt gatcattttt gatgatcttt caaaacaagc tgttgcttat
    10621 cgtgaacttt ccttgctact tcgccgtcca ccaggtcgtg aagcttatcc tggggatgtt
    10681 ttctacttgc actcacgttt attagaacgt gcagcaaaat taagtgatga tttaggtggc
    10741 ggttcaatga ctgccttacc atttgttgaa acacaagctg gagatatctc tgcttatatc
    10801 ccaacaaacg ttatttcgat cactgatgga caaatcttct tagaaagcga cttgttctac
    10861 gcaggtactc gtccagcggt tgatgccgga ctatctgtat ctcgtgtagg aggttctgcg
    10921 caaatcaaag caatgaaaaa agttgctggg actttacgcc tagacttagc aagttaccgt
    10981 gaattagaag catttacaca attcggttct gacttggatg cagcaacaca agcaaaacta
    11041 aatcgtggac gccgtacagt agaaatcttg aaacaaaaat tgcatgcacc gctagctgtt
    11101 gaaaaacaag tagtgatttt gtatgctttg acacatggat tcttagatag tatccctgta
    11161 gacagtattt tagacttcga acatgaatta ttcgaatatc tggataccaa tcattcagat
    11221 atctttgaaa caatccgtac aacaaaagat cttccagaag aagaagcgtt gaacagtgcg
    11281 attcaggaat ataaagacat gttcttagct acaaaaggaa gtaattcctc tacagaagat
    11341 aaattgaaat ccattcaaaa tgcatagtga ggtgagatga atgggtgctt cattaaatga
    11401 aatcaagaca cgtatcgctt caacgaaaaa aacgagccaa atcacgcggg caatgcagat
    11461 ggtgtctgct tctaagttga caaaatctga agcttcttca cagaagtttc aggtttatgc
    11521 aacaaaagta agagaaatcg ttacgcattt gactgctact cagttaaatg atattgcctc
    11581 agaaaatcct agaggggata tcaattacaa cagcatgctg ctcagccgtc ctgtgaagaa
    11641 aactggttat atcgtcatca ctgcagatgg cggtttagtc ggtggatata acagctcgat
    11701 attgaaacaa acgatgtcta ttttagaaga agaccaccaa tcacccgatg attacgtgat
    11761 gatcgcaatt ggcggaactg gtgcagactt ctttaaagca cgcggtatca atctagcata
    11821 tgagctgcgc aatctatctg atcagccaag ctttgatgaa gtccgcaaaa ttgtaaatat
    11881 ggcaacaact atgttccaaa acgaagtatt cgatgaatta tacgtatgtt ataaccatca
    11941 tatcaattcg ctaactagtc agtttcgtgt agaaaaaatg ctgccaatct cagacttaga
    12001 tccagaagaa gcaacgactt tcgaacaaga atatattttt gaaccttcaa aagaagaaat
    12061 cttgtctcag ttattgcctc agtatgctga aagtttgatc tacggtgcga tcgttgacgc
    12121 caaaacagca gaacatgctg ctggtatgac agcaatgaaa acagcaactg ataatgctgc
    12181 taatatcatt gatgagctga cggtttctta taaccgtgca agacaagggg ctattaccca
    12241 agaaattacc gaaattgttg ccggagcttc ggcactagaa tagtattgag attggaggaa
    12301 aaaagatgag ttcaggcaag attgttcaag taatcggtcc cgttgtcgac gtggaatttt
    12361 ctttagacca atccttacca gatatcaaca acgcattagt tgtttataaa aatgacgaaa
    12421 ataaatcaaa agttgttctt gaagcagcgt tagaattagg ggacggagtg atccggacca
    12481 ttgcgatgga atcaacagat ggtttacaaa gaggaatgga agtcattgat acaggcaaag
    12541 caatctctgt tcctgtaggt aaagaaacat taggtcgcgt attcaacgta ctaggagata
    12601 cgatcgattt agaaacacct ttcccagaag atgcggaaag aagcgaaatt cataaaaaag
    12661 caccagcctt tgacgaatta agtacaagta cagaaatttt ggaaacaggg atcaaagtta
    12721 tcgatttgct tgccccatat ttaaaaggtg ggaaagtcgg actattcggt ggtgccggtg
    12781 ttggtaaaac cgtactgatc caagaactga tccataatat cgcccaagaa catggtggta
    12841 tttctgtatt taccggtgta ggtgaacgta ctcgtgaagg taatgacttg tattatgaaa
    12901 tgaaagattc aggagttatc gaaaaaacag ccatggtgtt cggacaaatg aacgaaccac
    12961 caggtgcacg tatgcgtgtt gctttgactg gtttgacgat tgcggaatat ttccgtgatg
    13021 tagaaggtca agatgtactg ttgtttatcg acaacatttt ccgtttcact caagctggat
    13081 ctgaagtatc agccttgtta ggacggatgc cttctgcggt tggttatcaa ccaacattgg
    13141 caacagaaat gggtcaattg caagaacgta tcacatctac gaaaaaaggt tcgatcacat
    13201 cgatccaagc aatctatgtg ccagccgatg actacactga cccggcgccg gcaacagcat
    13261 tcgcccattt ggatgcgaca accaacttgg aacgtaaatt aacagaacaa gggatttatc
    13321 cagcggtaga tccattggct tcttcttcaa gtgctttagc acctgaaatc gtgggagaag
    13381 aacattataa agtagcaaca gaagtccaac acgtattgca acgatatcgt gaattacaag
    13441 atatcattgc tatcttaggt atggatgaat tatccgatca agaaaaagtg ttagtttctc
    13501 gtgcccgcag agtccaattc ttcttgtcac aaaactttaa cgtggctgaa caatttactg
    13561 gtcttccagg ttcatatgtc cctgtagaag aaacagtgaa aggattccgc gaaatcttgg
    13621 aaggcaaata cgatgatctt cctgaagaag ctttccgaag tgttggccga atcgaagacg
    13681 tcgtagaaaa agcgaaaaca ctaggctact agaaaggggt gccccatgga tcaatattta
    13741 acagtaaatg tggtaactcc tgccggtttg gtctatgatc accatgcagc tatcgtcgtt
    13801 gcacgtacga cagctggtga gcttgggatt ttgcctaaac atgcaccaat catcgttcca
    13861 ttgacgattg atgaagttcg tgtaaaacga acagattcag atacccacgt cgattggatc
    13921 gctgttaatg gcggaatcat ggaagttcgt gataatgttg tttcaatcgt tgctgatagt
    13981 gcggaacgtg aacgtgatat cgatgtatct cgtgcggaac gtgcaaaaca acgcgcagaa
    14041 cgccaaatcg aagaagcaaa agcaaaacaa gatacgaacg aattgaaacg ggcaactgtt
    14101 gcgttgcacc gagcaatcaa tcgtatcaaa gtatctaagc actcataaaa tgagatgcgg
    14161 atgtttatcc gtgtttaaga acagtaaaaa gaggttatga cagaagtggt cagcttcaag
    14221 acataagaag gaatttacga aaattgcttc tcaaattttt gtgaaatctc agcttatttt
    14281 tcgaagaagc tacttctgga acaccgtata tcagaggttg tgaaatcagc gttttgtcct
    14341 gagtattaga gaaacaaatg gaaaatagtt cctcatattt tgccgttttt tgagctaata
    14401 ccgagggtca gatgattgaa caccgtttat ttggaataag ggactgcgac aagacttttg
    14461 tctcagtccc tttttttgca tatttttagc atttatttcc taaaaaatgt aaggggattc
    14521 ctatattttt aagtatactt gtttttcctt ttatacattt tatggtatta tcattttatt
    14581 agttattata aaacaatcgt tagaaaggac gtcattatgc aagtatacgg aattgatgcg
    14641 gtgcttcgaa tcgtgagtca tttggcgttt atctacttag ccttctggtc tttacgttcg
    14701 ttacgcattg aaactttttt cagaccaatg cataatacgc aaattagaat ggcaatcgta
    14761 cttttttcaa tttttttagg gtacactgca agtaattttt tcttagaggt tatcgcttta
    14821 tgccgaaatc ttttcgttag cctgtaaatt ttaaaaaaag gtactatttt aaaagcaagg
    14881 atgttataat agaaaagatt ttgagtaagt gtatgctcat tggaattttt tggagggaac
    14941 aacatggaag agatcatcgt aagaggtggc aatcaattaa atggaacagt aagaattgaa
    15001 ggagctaaaa atgctgtttt gcctatttta gctgctagtt tgttagcaga agaaggtatt
    15061 acgacattag acaacgttcc gattctttct gatgtcttca ctatgaatca agtgattcgt
    15121 cacttaaacg tagatgtaga ttttgatgaa caaaagaatc aagtaacaat cgacgcttca
    15181 agacaattag aaatcgaagc gccttatgag tatgttagtc aaatgcgtgc ttcaatcgtt
    15241 gtgatgggtc cgctacttgc cagaaatgga catgcaaaag tagctatgcc tggtggatgt
    15301 gcgattggta aacgaccaat cgatttgcat ttaaaaggat ttcaagcttt aggagcaaaa
    15361 attattcaaa aaaacggcta tatcgaagca attgcggatg aattgatcgg taacacgatt
    15421 tatttagatt tccctagtgt aggtgctact caaaatatca tgatggctgc cgtaaaagca
    15481 aaaggaacaa ccatcattga aaacgtagct cgcgaaccag aaatcgttga tttagcaaac
    15541 attttgaata aaatgggcgc tcaagtctat ggagctggta ctgaaacaat gcgtattgaa
    15601 ggcgtggatc atttacatgc agtcaaccac tcaatcgtac aagatcgtat cgaagcaggt
    15661 acctttatgg ttgctgctgc aatgacacaa ggcaatgtgc tgattgcaga tgctatctct
    15721 gaacataacc gcccattgat ttctaaattg atcgaaatgg gtgcagaaat cattgaagaa
    15781 gaaggcggag tccgtgtcat cggaccaaaa catatcttac ctacagatgt aaaaacgatg
    15841 cctcatcctg gtttccctac agatatgcaa gctcaaatga cagctatcca attagttgca
    15901 gaaggtacaa gtgtggtgac tgaaacagtg tttgaaaatc gtttccaaca tttagaagag
    15961 atgcgccgta tgaacgctca tgtcaaaatc gacggaaatg tagcaatcat ggatggaaac
    16021 catgaattgc aaggtgcaga agtatatgca acagacttgc gggcagcagc agcattagtt
    16081 ttagctggct tgaaagcaaa tggaatcaca cgtgtgcgta acttgaatta tctagaccgt
    16141 ggatattata atttccatat caaactacag caattaggtg cagacgtcga acgtgtagac
    16201 atggatcaaa cttctgctga aaaaacagca caaacgattg cttaaggaag tggctgaatg
    16261 agtaaccaac gatatatctt attaactttg ataaagattt tagtggtgat cttattgctt
    16321 atccttcttt ttgtggccgg aacgatgatc ggatatggtg tcatcggtgg cggcaatcca
    16381 tttaaagtat tccagccaag tttgtggatt catattcgag acttttttca ttgataaata
    16441 agaatcacag tggttctagt cgatatgaag tgagccatga agcagaacat gataaaagaa
    16501 aacagaaggg aacgttgacg ttagtcgcga tccctttttt tagtaaaaga aaagaaggaa
    16561 tctaattgat gaagaagata ttgatttatt tagttagagg atatcagcgc tttatttcgc
    16621 ctgcatttcc acctagctgc cgttattacc caacctgttc caattatatg ataaaagcaa
    16681 ttcaaaccca tggtgcgcta aaagggacgg taatggggac tgcacggatc ttacgctgtc
    16741 atccttttgt caaaggcggt atcgattatg taccattgac attccgatta acgcgaaata
    16801 agaaagataa aaaagaacca gattataaaa aggttgtgaa aaatacgggt agcactgagc
    16861 gataaagaaa aagaggaaat ttattgtcaa agtaacaact ccgcaactac ttatatgggg
    16921 gacaaaaaat gatcgaagaa ctaaacaaga aagatttacc atggtccttg ttattagatg
    16981 cagatcctga taaagaaaaa gttcaagtat atgtttccag agggagtggc tggatatgga
    17041 aagaaaaaga aaaaacaata ggtgtactga tctatgtggc aagggaaaaa gaatacgaaa
    17101 tcgtcaatgt agcagtaacc ccaacgtatc aaggaaaggg gattggcgga aaattacttg
    17161 agacagcttt tcagaagctt tcacagctag cttcaaacca aactcggatc attatacgta
    17221 ctggcactac tagtagcgct gcgttacacc tctatcaaaa aatgggctat gtggagattg
    17281 gtcgagtcaa agactatttt atccatcatt actctgagcc catttttgaa aatggagatc
    17341 aattaaggga tcaagtgatt ttagcaattc acttacctaa aaatagcttt aactaataaa
    17401 ctttcaattc gagaaaatgc tttcaaatgc taaatagata cattacaata gctttagcaa
    17461 acaaaaagga gaatattttt atgggaatat tagtttttga ttttggtgga tcggctgtca
    17521 aatatggttg ttgggatggc aaagagatta aaggtaaggg acaatttgca acgcctgaat
    17581 cttgggaaga aatgaaaacg caattatttc aagtttataa aaaaatactc gtttcttttg
    17641 aagtcgaagg aattggaatc agctctcctg gagtagtgaa taatgagaaa caggtgattg
    17701 agggaatcag tgcgattcct tatattcatg gatttaatat tttccgagat ttggaaactc
    17761 tgtttcaact cccagtaacg attgaaaatg acgccaactg tgccggaatg gctgaatttt
    17821 atgaaggtgc tgcccgtgat tatcaagatg ttgcttttgt tgtggcagga actgggattg
    17881 gcggggcgtt gttcacgaaa ggacaaataa ataaaggggc acatctttac ggtggagaat
    17941 ttgggttgat gttcttagat ggcgataaga cattcagtaa acttggtaca gcggtacaga
    18001 tggcttggcg ttattgtgaa cgcaaaggtc tcgataaaaa tgcttatacc ggaaaagatg
    18061 tctttgaatt agcagaaact ggagatgcaa tagcaaaaga agaagttgag agtttttata
    18121 cgtatcttac aaagggatta ttcagtattc aattttcgtt tgatccagaa gtgatcgtat
    18181 taggcggcgg ggtttctgca aaagaagggc tcattgatga gatcaaaagc cgaatgaaga
    18241 agctgacaga acaattcgat ctgcatgatt tcgaaccgca gattttatta tgtgagtaca
    18301 gaaacgatgc taatcttata ggtgcagcag caaactatct cgctgtacgt caaggagaga
    18361 attaagagct ttagagaagg tgcagcttgc ataaaagaag agaatgaaat gaataggaga
    18421 tttttaccta aggaatgttt tatttgctgc agtatgataa aatatctgag aggtgaaaat
    18481 gatgtcaaaa aaaaataaag atattgaagt gcgtatagaa gaagtgaaaa aagatatcaa
    18541 aggtaagaat tatgaagtca ctcagttatt tatagggaaa aaaatgattg gtgagatctt
    18601 agcctatggg ccaaaagaat atgaaatttt ctttggtgaa gaagattttg gaaaagaaaa
    18661 aagtcttgaa aatgcgatag aaacagtgat tcgacactgg aatctgcacg aataaaaaaa
    18721 tatcaaaaaa actttcaata aagggttgca aaaatctgga aaattaggta ttataactaa
    18781 gtcaggttga tacaaacctt tcggaggagt agcgaagtgg ctaaacgcga cggactgtaa
    18841 atccgttcct tagggttcag tggttcgaat ccactctcct ccatttcatt ggggtatagc
    18901 caagcggtaa ggcaagggac tttgactccc tcatgcgttg gttcgaatcc agctacccca
    18961 gtataccaca atcgtaagct ctcgttagtt cgagagctct ttttttttgc tttgctacct
    19021 tgttccttga agattctgct gaattaagat agagttaagt taactacaag aattggaggg
    19081 atccacatga aatggaaaga aaaagtagac gaagcagctg aaaagttata tgatttggtc
    19141 aaatcagaaa aatacaatat tgaagtgaat attccgaaaa aaggcggaaa agcggtccag
    19201 gtaaaatcaa aacgcccaac gaatcataca aaaaaatgga tggctaaaaa ccgctaataa
    19261 taacaaaaga tccataagtc ggcattttca tcgattttag ggtcttttgt tattttctag
    19321 gttgaacata tctaaaaaat tgtttctgac aataggagta gggagaacga tgtgtgtcta
    19381 aatcctctgt tgatggatag aaacctttat ctttttcagt tgtgaatcag gtatatacca
    19441 gttataatag aagaaacgaa aggacgggtg tacgttatgt cgaatcaatt acctgtatat
    19501 atacagattc atgaccaatt aaaaaatgaa atcgaacaag gtatatggaa agtcggagac
    19561 cgtcttcctt cagaaagaga attagcagtg aaattcaatg tcagccgtat gacgttgaga
    19621 caagcaattc aaaacttggc agatgaagga atcttagaaa gaaagatcgg ttcgggtacg
    19681 tatgttgcgc gagaaaaagt acaagaaaaa atgtctggtg caacaagttt tacagaaatt
    19741 atggaatcac aaaatcgagt accgtctagt cggacaatct cttatttctt gacttcgcca
    19801 agctcaagtg aaatggaaaa actaaacttg agtaaagatg acacgatctt gcgaatggaa
    19861 cgtattcgtt tcgcagatga tgtccctatt tgttttgaag ttgccagtgt tccacaaaag
    19921 ctgatcgatg gctacagcaa agcagagatt actgaatcgt tgtatcgcac gctagaagaa
    19981 aaaggcggga aaaagatcgg tccagcgaat caaacgatta ctgctgtgtt ggcttctgag
    20041 aaaattgctg actatttaga ggtaaaacga agagatgcag ttcttcgttt gcgccagatt
    20101 tcttattttg aagacggtac gccgtttgag tatgtgcgta cgcaatacgt aggaaatcgt
    20161 tttgagtttt atttggaaaa ataaaaaaca ggtgatccct gattccttat tagaaataaa
    20221 agagaatcag aatcacctgt ttttatatat gatcagttat cagttgctcg tgataagaaa
    20281 cagaaccctc ttcaaattgg acttgtccgt tcagcagctc aatgatggat tctttaaagt
    20341 ggttagcact tttttcatct acagcacaga tgacgctaac ttgatcagta tattggattt
    20401 cttttataaa aaaatgttgg agttcaagat aattctgtaa ttttcctagt tgcggatacg
    20461 tgatcatcac agagatctcc tgttgcaagg taccttctac gattccaatg tcagacaatg
    20521 cttgagagac cgcatgagtg tatgctcgta ttaatccgcc tgtgccgagt ttcgttcctc
    20581 caaaatatcg agtgactact gcagctacat tgatcagttg attttttttg aggacttcca
    20641 acatcggtac gcccgccgtt ccacttggtt ctccatcatc gctgcttcgc tggatttcat
    20701 ttttttctcc aatgatgaag gcgctgcagt tatggttcgc tttccaatgt tcttttttta
    20761 tttcttgaat gaaatttttt gcttggtcct ctgattctat tcgtctaaga gaacagataa
    20821 agcgtgattt tttgatctca atctcacttt gtccattttc ttttattgta cgatagcgct
    20881 cgatcatctt gtcacctctt tttttcattt tctttattca gtataaataa agttctaggt
    20941 tgtttcaaca ctgtaacggt tgcgcaattg ctgtagtatg cgataataaa gacaaaggca
    21001 ggtggatctg gggatgcagg aacgaatgaa aaagtacgat gcaattacgc attatttgaa
    21061 gaacaatggc ggctctcaag taacgttgac ctttacccaa tttgacgaac tgctgtttcc
    21121 cagtaacgga cttcccaaaa cagcaaggga aagtacagat tggtgggcaa atgattataa
    21181 acaccctgaa aaaggtgcct atggctggat aaatgcaggc tatgaagtag ttgtcatcaa
    21241 tttggacaaa gaatatgtcg tgttcaataa attagtgaaa tctagttggc tatttgatta
    21301 aataaaccgc gtttagaaaa cgttgacaaa tttctttctt tttatataat aaagtaacag
    21361 acgcgaagaa aacgtttgcg tagtttgttt taaaaaggag agaaaaatat ggctaaaaaa
    21421 acaatcatgc ttgtatgttc ggctggtatg agcacaagtt tactagtaac aaaaatgcaa
    21481 aaagctgctg aagcaaaagg aatcgactct gatattttcg ctgtgtccgc ttctgacgca
    21541 gataacaatc ttgcaaataa agacgtggat gtgttgttat taggcccaca agttcgcttt
    21601 atgaaagctg attttgagaa acgtctggaa ccaaaaggca ttcctttaga tgtcatcaat
    21661 atggctgatt atggtatgat gaatggcgaa aaagtgttag atcaagcaat cgcgctcata
    21721 ggtgaataaa tagaacagta taactatcga acaagcgatc caaaaaatag atcgcttgtt
    21781 ttttcgtata tttttttagg gcgaataata tgaatcattt ttggggtaga aggcttctga
    21841 cgagagatat taaagcaata gactgtgagg aggtaaattt accaaattat gagaagatcg
    21901 cagcagtgga acgtttgggc aactggattc tttgtcatcg ctgtggaatg aggacgtccg
    21961 tcattgttgg acagcttgca gattacggtt atttttgtac acattgtcta tatttagggt
    22021 gatgcgacac tcaacaagat ttatatttgt ttgatcagcc tgaagcaaaa cctcgagaag
    22081 tcgtcttttt ttggacagga cagcttactg aaaaacaaac ggaaatcgca aagagaatac
    22141 tttgccattc agaaaaaaga catcatctta tttgggctgt aacaggtgca gggaaaacag
    22201 agatgcttta tcctatttta gtggaaactt taaaagctgg aggaagagta gcgatttgta
    22261 caccgcgagt cgatgtttgt aatgaattgt ttttacgcta tcgttatgtt tttccagaag
    22321 aaaaaatcac gttgctccat gggaatacag caacggctta tacctttact tcttttgtta
    22381 tctgtacgat tcatcagcta taccgttttt atcggtcctt tgatttaata gtgatcgatg
    22441 agatcgatgc gtttccttat aacggggatg ctgggctagc tcacgctgtg caaacagcaa
    22501 tcagatcaaa cggccgattc atctacttaa gtgccacgcc tgatgagaag ttactaaagg
    22561 aaatcaagca gacatttgag ctccacaaac ttgccttgcg ctttcatcgg cgcttgcttc
    22621 ctgaacccgt gcttgttttc atgaataatt ggcgacaaaa atgtggaaac aaaaagaaaa
    22681 tcaactcttt ggtgcggatc attcagcaac taatcaaaga aaaccgtatc cttttatttt
    22741 gtccaagtat tacgatgatg catcgtttaa aaatcacact gcaagaagct tttccagaat
    22801 atgagataac agatgtttct tcacaagacg atcaacgggc aaagaaagtt cagaaaatgc
    22861 gagaagcaat atacgagata ctgttaacca caatgatcct agaaagagga gtcacatttg
    22921 aaagaatctc tgtcatcgtt ttaggagcag atcatccagt ttttactaaa tcctctttgg
    22981 tgcaaatcgc aggaagagct gatcgtaaag gtccttatac gaacagtcga gtctattttt
    23041 tctatgaaga aaaaacttca gctattcgaa aagcctgtca ggaaatcaaa gaaatgaacg
    23101 aagaagggaa gcagatgctg tgagatgtag ttgctgcggt aaagacatca ttcaaaattt
    23161 aacattcagc gagatcatcg gagtgtcgaa atctagactt cctcagacat gttcagtttg
    23221 ccgcgcacaa ttccatttat tagaagcaaa aggttgtgca ggttgtcaaa aaccaatcca
    23281 tttgaaatac gaggagacga aaaagaaagc aaatactagt ttcgtttact gcaacgactg
    23341 tcaagaatgg aagaagaaat atcctgcata tgattttcaa caccgcgcct tttttacgta
    23401 cgatgaaaag atgcaggctt ggatcaatcg gtacaagttt atgggagata tccgattagc
    23461 agggactttt gcatataaat ggactcagat aaaaaaaaga ttacccggca tatatttatt
    23521 gtccaatacc tttatctgaa aaaaggtggc tagaaagagg attcaatcaa gtaagcgaga
    23581 tgttgaaagc agcaaaaatt ccttttcaga tgctgctcaa aagagagcaa catctgcttg
    23641 ctcaagcaaa aaacacgcga aaggaaagat tggagatgcc tcagcctttt gagcttgccg
    23701 tacctctttc taagatacaa cataaaaaa
//
LOCUS       DADVXV010000041        23717 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.042, whole genome shotgun sequence.
ACCESSION   DADVXV010000041 DADVXV010000000
VERSION     DADVXV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.042"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(154..894)
                     /gene="truA"
                     /locus_tag="KB969_001530"
     CDS             complement(154..894)
                     /gene="truA"
                     /locus_tag="KB969_001530"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBB6869520.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(1085..1720)
                     /locus_tag="KB969_001531"
     CDS             complement(1085..1720)
                     /locus_tag="KB969_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBB6869521.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(1867..3108)
                     /gene="sstT"
                     /locus_tag="KB969_001532"
     CDS             complement(1867..3108)
                     /gene="sstT"
                     /locus_tag="KB969_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBB6869522.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            3306..4304
                     /locus_tag="KB969_001533"
     CDS             3306..4304
                     /locus_tag="KB969_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869523.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            4317..6335
                     /locus_tag="KB969_001534"
     CDS             4317..6335
                     /locus_tag="KB969_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBB6869524.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(6395..7111)
                     /locus_tag="KB969_001535"
     CDS             complement(6395..7111)
                     /locus_tag="KB969_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBB6869525.1"
                     /translation="MKKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTS
                     TESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNAD
                     KSAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEW
                     SESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFN
                     ETANNELKNGFNQIVYGQAN"
     gene            complement(7338..7880)
                     /locus_tag="KB969_001536"
     CDS             complement(7338..7880)
                     /locus_tag="KB969_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6869526.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(7885..8112)
                     /locus_tag="KB969_001537"
     CDS             complement(7885..8112)
                     /locus_tag="KB969_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6869527.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(8191..10071)
                     /locus_tag="KB969_001538"
     CDS             complement(8191..10071)
                     /locus_tag="KB969_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBB6869528.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(10260..10874)
                     /locus_tag="KB969_001539"
     CDS             complement(10260..10874)
                     /locus_tag="KB969_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6869529.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            11016..11576
                     /locus_tag="KB969_001540"
     CDS             11016..11576
                     /locus_tag="KB969_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6869530.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
     gene            complement(11881..12195)
                     /locus_tag="KB969_001541"
                     /pseudo
     CDS             complement(11881..12195)
                     /locus_tag="KB969_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(12449..14084)
                     /locus_tag="KB969_001542"
                     /pseudo
     CDS             complement(12449..14084)
                     /locus_tag="KB969_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14523..15392)
                     /locus_tag="KB969_001543"
     CDS             complement(14523..15392)
                     /locus_tag="KB969_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6869531.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            complement(15412..16533)
                     /locus_tag="KB969_001544"
     CDS             complement(15412..16533)
                     /locus_tag="KB969_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBB6869532.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            complement(16535..16930)
                     /locus_tag="KB969_001545"
     CDS             complement(16535..16930)
                     /locus_tag="KB969_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6869533.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            complement(16949..17755)
                     /locus_tag="KB969_001546"
     CDS             complement(16949..17755)
                     /locus_tag="KB969_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6869534.1"
                     /translation="MNKMSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALS
                     PILRKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKV
                     GTMGPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEF
                     GYKQGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQP
                     MLDKILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            complement(17748..18536)
                     /locus_tag="KB969_001547"
     CDS             complement(17748..18536)
                     /locus_tag="KB969_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6869535.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            complement(18550..19026)
                     /locus_tag="KB969_001548"
     CDS             complement(18550..19026)
                     /locus_tag="KB969_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869536.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            complement(19098..21755)
                     /locus_tag="KB969_001549"
     CDS             complement(19098..21755)
                     /locus_tag="KB969_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6869537.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKR
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            complement(21774..22178)
                     /locus_tag="KB969_001550"
     CDS             complement(21774..22178)
                     /locus_tag="KB969_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit M
                     N-terminal domain-containing protein"
                     /protein_id="HBB6869538.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            complement(22410..22667)
                     /locus_tag="KB969_001551"
     CDS             complement(22410..22667)
                     /locus_tag="KB969_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBB6869539.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            complement(22792..23124)
                     /locus_tag="KB969_001552"
     CDS             complement(22792..23124)
                     /locus_tag="KB969_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869540.1"
                     /translation="MPLDLSTGRKIRFSEIQYEGIGFTLIDLKNSTFEIKEGLDLKNL
                     LCADDKIKKIQLYKVPILTPTVLTMLEMENNINYIDSGSDLLIRWQVITNFLMELKKY
                     SNTQTKFS"
BASE COUNT         7475 a         4695 c         3608 g         7939 t
ORIGIN      
        1 tctcactaga tttttattta agaaagactt tttagctgta cacataaaca ggctaaaaag
       61 tcttttttta tatttcttta atttgcttca tacattattt aacatcgata tttatactgt
      121 gaaacatgcg tttcatccat tatcaaagta tttttatcga taataaactt catccaaaaa
      181 cagaccttgt gcagggacgg tttctcctgc atgttgccgc actttgcttt caaatatttc
      241 atcgattgtt tctatcggca tggcacctgt gccgatttct agtaatgtcc ccatgataat
      301 ccgcaccatt ttatataaga atccgtctcc gacaaaagta aaatgaagca tttctccctt
      361 tcgttcgata gataattcat caatcgtacg cactgtggat ttttttgatt ttttcaatgc
      421 agaaaaacca atgaaatcat gtgtacccac taatttttcg caagctgcat tcagcttgtc
      481 catatccaac tcttgaggga aataaaagct gtggtttcgc tcaaatgctg aaggaatcac
      541 gttgttccaa acataatagc tgtatttttt gcccaccgca ttatatcttg aatggaagcg
      601 ctcaggcatt tcttcgattc ttttgatgac aatatcccgc ggaaggtaac gattcataaa
      661 gtcgatcatt tctgccagtc caatttctgt gtttgtttta aaatttgcta cttgtcctcg
      721 cgcatgggtg ccagcatctg ttcttcctga tccaataatt tctatctctt catttgtcat
      781 ctgatgcaat actttttcga tttttccttg aatggtttta tcgtcatctc caagtctttg
      841 ccatcctgaa tatctttttc cgtcatattc gattgtcaac ttgatgtttc tcatatttta
      901 gtggctcctc tgtcttccat ttggtcttct ctctaccttt ttaagattgt agcacaaaat
      961 atagctcctt gcttctctaa gacagaagct atacaagaaa actgtggaaa tatatatttc
     1021 agaaaaacaa aaaacagcca ccggatgaag tatccgctga ctgttcaatt tgacggctca
     1081 agttttactg tttgagatgc aagatactca accaggcaat gggcacataa ttaaagaaaa
     1141 aactgattct ttggcaaaaa cctattttat tcagtaatgg ccaagaattt atagaaggaa
     1201 ttcttgccag tccataaatc gccgcaaaaa gcaaactgat cacagacagt ccaaggtata
     1261 agtggcttac gtccatttgc ccattttttc gatagatcaa gaaaagaaga actggaaaca
     1321 ataaaaaacc actgtaacct aaacctgatc cgatattatg gacccatgtc gagacattcc
     1381 acgaagattc atgggtattg atactgaaca aacctgtaaa gatacaatca cctataccat
     1441 agaacgcgat ggctgctgta actagggtag ctaacacacg agatgtacta acaaatgcag
     1501 catacaatgc aggcaatgac aggatgaaaa agatccctga aaccacagac caaataagaa
     1561 acgcttttct tacaggactg gaaacctctc caaatacact gatcacgctc ttcatttgat
     1621 ctaattcagg ataatacaat cctaatacgt acggagtcaa aaaatcactc agcacgccta
     1681 ataataaaaa gaaaaaacca aatttacgta aaaaatccat gatacgcctc caataacaat
     1741 tacctatgct tttaattgtt attataaacg actttatctt gatttaacag aaacctctat
     1801 ttacacgaac atctatataa ctcattaaaa actcgaatca ttttaaaaat actaaatatc
     1861 taacgttcaa cgttcactta atccatctaa acaatctttc aatttgattt tttccccact
     1921 tcttttacgc gcgcctagct ctcctattgc agtaaacaac agatcacttg acgaatttaa
     1981 ggcagtttcc attgaatcct ggataacacc gataataaat ccaataccga cgatttgcat
     2041 cgcgacatca ttagagatac caaacaaact acatgctaat ggaatcaata acagtgaacc
     2101 gcccgcaaca cctgaagctc cacaagcagc taaagcagac aaaatacata aaaggacttt
     2161 caaaacaaaa ggtgcttcaa tccctaaaga atgtacagca gtcaacgtca tcaaggaaat
     2221 ggtaatcgcg gcaccgccca tattgatcgt agcacctaac gggatcgata tggaataaga
     2281 ctcttttgtc aatttcaatc tttcagccaa catcatgttt atcgggatat ttgcggcaga
     2341 acttcgggta aagaaagcgg gaagtgcgct ttctttcaaa caaaagaaaa tcaatggata
     2401 gggattttct ttaataaaca aaaacgtgag gaatgggtac acaactaatg cgacaaacag
     2461 catcgtaccg atcaaaacaa gtaaaagctg cagatactct gccaatccag cgattccagt
     2521 cgtagcaatt gattgataaa ccaatcctaa aatccctatc ggagcaaatg caataatcac
     2581 ttgtacgact tgtgacaacg ctatagatat ctgatccacc aactcttttg tcgattctga
     2641 acgtgctcga aaagctagtc ccaacaatac agcccagaat aagacgccaa ggtaattcgc
     2701 atcaataaga gattgaacag gattttgtgt gacattcgtc aacatagtag ataaaacact
     2761 ttccaaactt tgcggtgctt tttcagatac tgtttcttgt aaagtaatag gaacagtaaa
     2821 aattgaactt acaataactg ctacaagtgc agaaagcaat gttcccacta aatataagat
     2881 caaaataggc ttcacgaatg tcttattccc aattttatgc ttggcaattg acgccatcgt
     2941 caagaaaaaa accagaatag gtgcgattgc cttcaagcaa ctgacaaaca acgttcccaa
     3001 tattgaaata aatgtccatg tggggaaaaa gataccaaac aatattccga ctaaaatacc
     3061 aacaacaata cgttgaacta acgacatatc caaaaacttc tctaacaaat gaccaccctt
     3121 tcacaatttt aacaatcatt gtatcatttt atgcaaagaa actaaaggta taattttcta
     3181 aaaattctaa caatacaaac aaccatttct tgctaatttt gtactttttc tgtctacacg
     3241 ttgttttttg agatattcta agttaggatg ttattaatgg gcaacttatc aggaaacgtt
     3301 ttcttatgtt tttgtccaat ttttttgtga ggtgtttatt cttgaaaaaa ataaagaagg
     3361 agagttatgg cttcctgaca atctttgtcg cttgtataat gatggtttta cagcgtatat
     3421 tgatttcagc agtcactatt cctacatatg caacaaaccc tggtcgattc tacatctata
     3481 catttttaca aacttccgtt gttattggtg caaatttgat cccactttac atgggttacc
     3541 aatatcaaaa aatcgcccgt ttaaaagttt tacattattt aagtcgtttt gcctttatat
     3601 tcctaatagc cacactagtt tgcaatatct ttttttacgt acaagctggc agcttgaata
     3661 ttcgtgatta ttggcttatc ctaacaccta tcagtcagaa ttactttact tatgctgttt
     3721 cttgtacttt gcttttttgt agtattcctt atacagttgg atttttaaat aaattatcga
     3781 aaacaacaat taaatatcta ctattatttt taacaattgg attagttggc tgctctactc
     3841 tatttaataa agacccgttt gcattacaga atggacagag tattttatgg attttttatt
     3901 tatttttaat gggttatggt ttgaaagaat ggaactggaa agaaaaggtc cgctataagc
     3961 ttcctcaagt atttatcagc ttgattgttt tattcggttt gattattttg atgacacaaa
     4021 tttcactcat catcagagga aatacagata cagcgctgag gttttctaaa ccatattctc
     4081 tcttcgcaat gtattatact ttctcttcgt ttttattttt agaaatgcta tctgataaat
     4141 taggtataaa aggaagagga aattttcttg ctgtattttt gattgtcact caagttatat
     4201 gtaatttccc tttagtttct tatcgcgtat ctacatttat gaaacgtgaa tttccaaact
     4261 cagggaaggc atggctgata aatatcgggc agttttttat ttgatattta ttagcagtgt
     4321 ccctcctagt tatcttttta ttttatatac aaaaaatccg tttcattcat cgtttcatcg
     4381 aatacttcgc ttttgattcg attgaacaat taactcagcg ttggaaaaaa agaattcatt
     4441 ggctttttgt tcataaaagt tattttttag ttgcagcatt tttttactgc tttaccttcg
     4501 tgcagatttt cgttttagaa ccaaaagaag gttggaaaga aactatccag gttgccttaa
     4561 aaatatttac tcagcgacaa gcacccatga tcctgacaat catcattatt atgggatttt
     4621 tcttcttact attgttgatt tccaatcgtt tttggtacgc cttgactgct accttgatca
     4681 ttaacttact gctcactatt tcgacagtaa tcaaaatgga aatgcgggaa gagcctgtct
     4741 ttccttcaga tttaaaaatg ctgaccggat tgtcagaact attatcgatg gttagcccag
     4801 tcttattaat cgtgggcgga ttgatccttc tcctattatt gattactagt attattgtac
     4861 aacgtagact acaaaaacag tattccttga agattcattg gaaacgtcga tttatcagta
     4921 tcgctgtatt attaggatgt ttttcgggtg tctttttcat taatcacaaa aattcgcctt
     4981 ctttcttgct gtttaattta tttaaagtaa acaagacttt ctttaaccag caaggcgccg
     5041 taaaagataa cggaccagtc attcaattcc taaacaatat cgacattaaa atcatggaag
     5101 aacctgctgg ctattcgaaa gaaaaaatta atggaataat gaaaaagtac aacacaaagg
     5161 cagatgaaat caaccaaaca agaagtgact ggttaaacaa tcagacgatc gttctcaatt
     5221 taagtgaaag cttcagtgat cctgcacgtg tccctaatct gacagtacct acagacccta
     5281 ttccttacat caaaagcatt ataacagaag gaacaggagg attgatgtta tccgtcggtt
     5341 atggtggcgg aacagctaac atggaatggg aaggactgac aggcttgagt atcagtaacc
     5401 tgtctgcttc gttagttaca ccttataccc agctagtgga gcgtcagaaa ataagtccaa
     5461 atattaccga tctattcgat gaaaaaatag ccatccatcc ttttacagct gctctttatc
     5521 gcagaaaaca agtgtttgat aaatttggtt ttgacaggtt ctattattta gacagtccgg
     5581 ataaattaac ttatacggat aaaatagaac aaagcccacg catatcggat gattcagcat
     5641 acaaagaaac cttgaaagct ttacaaagca atacggaaac gtcacaattc atccaattat
     5701 ccactatgca aaaccatatg ccttatgatg attactatag tgaattgaac tacactgctg
     5761 aaggaactgc tgtcattcct aatagaagaa aagaattaca aacttatatg caaggccttc
     5821 actataccga tacagcagta aaaaaattca tccaagaaat cgacaaaatc gataaaccga
     5881 ttacctttgt tttttatggt gaccatttac ccgcaatcta tagtgggaat gattcgaaaa
     5941 aatatggatt agaacagcac cagacagatt atttcattta taacaacaag tatagtcgtg
     6001 aacaagcagc tacgttaaat aaagaagttg ttgctcctaa taactttggt gctatggctc
     6061 ttgagcatgc gaatatcaaa gtaactcctt actatgcgtt gttgacagaa gtatctaatc
     6121 atctacctgc attaacaatt gatcctacag aaagcttgtc taatcgtttt aatggaaaac
     6181 aggtctttgt tacagaggat agtcaaatta tccaagaaaa aaatttaact gagaaacaaa
     6241 aagaaattct agaagattat cgtctgatac aatatgatct tgttgcaggt aaccagtaca
     6301 gtgcaacatg ggcgacacaa aaaataaaag actaacaaat aaactgagca aggggttgtg
     6361 ataaaagaca tgtcacaacc ccttgtttat ctcattaatt tgcttgtcca taaacgattt
     6421 gattaaagcc atttttcaat tcattattcg ctgtctcgtt gaagtaaaga taattatcgg
     6481 gattcccctg attttgttgt gtcaccaata cttttggctg attttgctga aacccgaata
     6541 gatagacgtg ctttttcaga tatggttctg tctctgcatc ggaatagacg gctgtgattt
     6601 gatagtctgc ttgacctgtc ccactttctg accattctgc agaaacaggc actccaccaa
     6661 tagccatctt ccactccccg ttcaaaatag cttgagggac tttaagacca tataagtcca
     6721 cactcatttg attcgtataa cttttgtatt gttgtcccat tgtttggccc catttggtca
     6781 taaatgcctc taattgtgcg gatttgtctg cattccacag tgtttgttca acttgttcgc
     6841 tgctttctga agaggaagat gaagcctcta cagaagaact tgaagtagat gtttgagttg
     6901 tttcagtcgt tttggaagac tctgacgaag tagaggtatc tgctgtttct gtacttgctg
     6961 cagttgactt gctctctgtg ctagttgttg tagtagttgc aactgttgct ttcgctgttt
     7021 cttttgttga ttcttttttc gattcattcc cgttggtaca accagctaac aaaaaagcta
     7081 gaccaattgt tactaaaatc ctttttttca attaaaaaac tcctttcgat tactcccact
     7141 tctttattct atcaaataag caatgtgatt ttattgattt ttcgtatttt ctcatcaatc
     7201 tttcaaatct tctaaaaact gagaagcacc cgctgatgtt gtctgtaata catcagcggg
     7261 tgcttctttt attttaatct tcgtgatttt ccaatttacc tcacgcttta tatttgtatt
     7321 tgaagaaaca tagactttta gtcatcatcg tcttcctcat ccaaatcttg tcggacagtt
     7381 tttccttgga gtctttgtac ttggtagatg atttctttat tgaaacttaa aagttcaaca
     7441 agcaattgtt gcaagccata tttttcttct ttttcagcta atttgattgc ccgtgtgata
     7501 aagacatttt ggaaatcaaa atcttttgca aagttttcca acattgttga ggctggtaaa
     7561 tatttgtttt gaccatgttc gtaaattttt ccataacgca tgacttcttc taaagtagac
     7621 ggaacgattt cattttcaat cactaactca tgagagattt tattgaacca tctcgcttct
     7681 tgatcagcat attctgaaaa aagggtactt aattcttgcg aagatgtacc caaaacatac
     7741 aattgtgctt ggatcaattt catttcttct aatttaaaat ttgctaatac atgccccacc
     7801 atggcgccag cagttggttt atgatggtcg atatctgctt gttttgtttc ttgaacaaat
     7861 ttttcttcca ctatattcat tgatttacgc ctcttttact tttgctgatt ggacttcata
     7921 acctaatttt tccacaactg cagctaattg ttcagggtgg acttcatctg gatcaaagtt
     7981 tgctttgatt ttgctcgcat taaacaaaac tttcgtattg cttaccccag gctgttgaga
     8041 aaccgcatgt tcgatttttt gcatacagct tggacaagct agtgtatcta attgcataat
     8101 aatttttttc atcgtagttc ttccttcctt tttcttgata gtcttattct agattacagc
     8161 ttccataaaa aaattgattc ttatcaagtt ttacgatttt tcttctttgc tttcgtgtcc
     8221 aaaatacaat aaacgcatcg cgttaaagat aacgatcaag atactagctt cgtgaacgaa
     8281 catcccacta gccatgtaaa taaacccggc aaataagccg ttgagtaaaa ataagacgac
     8341 accaatggca atcactacat tttcacgggt atttaaaaca gttttcttag ccaagcggta
     8401 ggcatgaacc aacgattcaa aattagattg catcaagaca acgtcactcg tttcgatagc
     8461 aacatccgtt cctgatccca tagcaatccc gatatcagcc gcagccaaag agggagaatc
     8521 attgattcca tctccaataa aagcaacgcg caatccttgt tcttggtatt ttttcacaaa
     8581 ttgaaccttt tcgtctggta ataattcagc atggacttca tcaatgccta acatatcagc
     8641 tacataatca gcagtcatct gattatcacc tgtcagcatc actaactgtt ttgctcctgc
     8701 ttgtttcaac ttagctaatt gttcagcgac ttctggtcga atcacatctg acacacctat
     8761 gatttgagtg atttttttgt cgattgctac aataatgacc gagctgcctg tttgttgtaa
     8821 ttgatgtaaa tcttgtactt gctttggtgt gagagaaagt ttgtgagcgg caatcaattt
     8881 ggtgttgccc gcacaaactg tatgaccatc aatctcagct gtgattcctt gtcccttgat
     8941 tgtctgatta tctttgactg ctaattgttg aaaatcaatg tctttctcct gagcataatg
     9001 gatcacggcg cgccccagag gatgatcgga taacgtttct aatcgagcca ctaaagctaa
     9061 gctgtcccct tcatcctctg tatagttctt gatagtggat acagcagtag ttcctttggt
     9121 caatgtacca gttttatcaa agacaaaagt atcgattttg gaaaaagtat ccattgcttc
     9181 accgcctttg actaagatgc cccgtttcgc tccattaccg attcctgcta cattcgaaac
     9241 aggcgcacca atgactaaag cgccaggaca accaagaacc aaaacagtga ttgctaaacg
     9301 aaaatcacga ctaatcagac caacaaccaa cgcaataagt aaaacggttg gagtataata
     9361 ctgagaaaat cgatcaatga atttttccgc atgggatttg gtatcttgtg cttcttctac
     9421 taattcgata attttggcaa aggtcgtatc atctccgacc ttagttgctt caatcgtcac
     9481 gtagccatct gctaaaatcg ttccagagaa gacttcatct ccactgattt tgacgacttg
     9541 tcgtgattca ccagtcactg cggcttcatc cgcataccct ttcccgtcaa tgactcgtcc
     9601 gtccacagga atagctccac cagtttttac taagacgata tcgccttctt ccacgtcatc
     9661 gatttccact tcttcagtcg ttccatcttc ttggacaaca ctagcagtag atggggccat
     9721 ctcggtcaaa gccttgattg actcccgcgt tttggtcaat gttttttgtt ccagatagct
     9781 accaaacaaa aacaagaatg taacgatagc tgactccttg tattctccga tcataaaggc
     9841 accaagcaca gcaatagtaa cgagtaaatc aattgagata actttgactt tcactgcctg
     9901 atacgcatgg atcataatag gtatgaccgc aataatagaa gctatggcta gagcaatgtt
     9961 atagaacaag acaaaaccag taaattttcc gataaaacca aaaataatca acacagctga
    10021 taaggcggtg atatgatttc gatgctcttg gatccacttt tgtaatttca tctttctccc
    10081 tcttttcctt tcattcttac gagactaagt atagatactt atccatcata aaaaattgac
    10141 cactatcaag tttagtcaaa aaggcggttt tcttttggta gaatacacta caaaaaatag
    10201 ttagcaagaa gactcactaa aagtgatctt gccaactatt gtcgtttcta tcgaaatttt
    10261 cattgaatga ttttcctgta cagcatacat cggagatcta tttctttatc taagattttt
    10321 atcttgctaa ttttttcctt tagtctttca aatccacgtc gttcatagaa ttgatacgta
    10381 cagccactat ctgtaaaaag gaatatttct tttcctttct ctcttttttc aaattctgtt
    10441 agcaacttgg taccgatgcc ttttgttttc aaatcaggat ttgcagctaa aaaaatgatc
    10501 tctccatctg gcgaatgctt ctttaaatat gctgcaagca tttgttcatt tgctgtctcg
    10561 taagctcctt tactttcttt agcaaatata ttttgtaaaa aatcgaatat cttaacatat
    10621 atttgctgtc caaaagaacg atgtttcttt ttttctcctt ttatctccgc cagcaaaaca
    10681 cctgccaact cgtcctctgc atacaaagca agaatttgag ttgctcgatt caactccata
    10741 tacaaaaaat atcttccgta aagattcagc agaagttcat tttccatata tctctcaaag
    10801 ttcattcctt caacagcaaa atagatagct tttttgtaat ctttcttttc taagggttta
    10861 aaagttagtt tcatcatttc gcctcctcaa cttcaatgat tgtgttatac ttacattata
    10921 atagacacag tgtctactat ctataatcaa tcatctataa gtttgtcgat taagcgacag
    10981 ctttgctttg atatgtcgga taaggagata ggtaaatgaa aaagacagat agacgcgtca
    11041 aaaaaacaga aaaagctttg gctgaaacac tatccacatt attagtaaat aaaaagattc
    11101 aagcaatcac tatacgcgaa ctaacagaaa cggcagatgt acatcgttcg actttttata
    11161 cacattataa ggatatctat gatctatatg atcaattaga aagcaacttt tttcgggatc
    11221 taaatgaaat tctctcttat gatccagccc atagctatga ggaactatac actcgcttga
    11281 ttgactatgt ttacgcaaat acttttttat atcgcttatt tatcctcaac catggtgata
    11341 tttcgtttca gaagaaagtt aaacaagtta ttgaagaaaa ctatctgaac atatggctat
    11401 atgaagacaa gaaaacgatt atcacagaag aaatgagatt ctttactacg taccacgtcc
    11461 aaggttgtct atccgttctc aatcggtggg tagaaagcaa ttacaagtac tccaaaaaag
    11521 aattattaga actcttacag aaactgaatg atcacataga gaaaatcatg ccttgaataa
    11581 aaacatacta agcttagtta agaagaaccg taaccttctc gtataacaac tgaatcttat
    11641 ttagccaaat tgtttactga agattttttg agtaaaattt ctataattcc tacttattga
    11701 aaagtagttt gtagtgctgc ttctccctct ctaagtgata tatcttgttg taccaatcaa
    11761 attcacctca tcattaataa attactttta ggctaattta ttacaactta taggttgaag
    11821 ctgtaaccaa tttatagtca tattatattt ttatcatcca gtttattgaa ttcttctcgt
    11881 ttacctcaat tcattttcaa ggggaatcag ctcatcatct aacattttac gccatgctcg
    11941 cttcatttct tgtgggtatt taaatggttt cgcttctgga tgtttggctt tatatccttc
    12001 gtaatcctta ctgttgataa ttgctttcat attaggaatt ggatcttcac ctggcatata
    12061 ttgcagatta gaagcatgta attttttctc agaaacaaac cactcattgg aaaagacatg
    12121 aatcaaatca tcacttactt gtgtaaaata gcgacgttta atgacaaaga tatcttcatt
    12181 gctatctagt gtaccttcat ttctttgtgc ttaaattcaa agataatttt ctcaataaag
    12241 atttttgatt ccagtaagat tcctttactc cttttacaac atagcgttgt cctttgtttt
    12301 gaaacatctt cttcccctct ttgccattaa aaatagccca attctctata aagaagatta
    12361 agcttcatta ttataatata aagtttaaat ttggtttatt acttactttt tcttattctc
    12421 tagtaagcta atattgaaaa aaatgtaatc agatcattat ttttatatgt tgtaacttcc
    12481 tgataagaaa actaattaaa agaaagaggt aactacataa actaattaaa aaagctaact
    12541 tcatagttgg aggataaatg gaagaaactt caatgattgt ttctccttgt gttccttcaa
    12601 tcgacactag tcctattatc aatctctctt ttttgtccat ttacttttgc gactgttccc
    12661 caataatcaa atacaggaag cgttattttt tgtcctttag attcatgtac tgtatagact
    12721 attttcgaat ccatcacttg ataaggcata gtatgccatt ccttgccaat tcttacttca
    12781 tgattctgca aatgttcttt gtattgtaat gcttccgtgg gtgcatagtc ataaagtcct
    12841 ccgggaagga gtgtcgtgta acgaataaga ttttcttgat tcattaccaa gtgatctctc
    12901 tgagtgacaa ctttatgttc atagtttgct tttgttgcag cagatacagc caacagtaat
    12961 aaaacaattg ccgttatatt aactactttt ctttgcttag ctgatgtgct cttcatgaaa
    13021 acgaacgata aaatcaacga gccaaacagt acttgaaagc ctaagattcg ccaaggaaat
    13081 tgaatcattt gaatgggtgt attttgtaat aaagaccatg gaaaaaattt ggtggataag
    13141 agccaagaga ctaccgcact aaggtaaatc actttttctt tgcgattaaa tcctttaaaa
    13201 aagaagagtg gacagatcaa agaaataata ccaatgattc ctaccgtaaa ggttgtcagg
    13261 tcattattca tcgcaccaat caaactatcc gagacattta atgcttggtg ttgtaaggtc
    13321 gttttatctg gctcattaat cgattgaacc atgatttgtc ggaacatcgg ataccaaaag
    13381 tatgctgtta aaagaatcgt cattcctact gcctttgaca actccacaat caaccggatg
    13441 ctttcttttt ttcttgtttc acttactaca aagccgccta agactagtaa gccaacggct
    13501 attacactca taaaagtgga aagaacatgt gtataaatga gtaagctcat actgactgct
    13561 aatggaattg cacatggctt tttctcataa atcagtgcgt aagcataata cataactatc
    13621 ggtataaccg taagtgcaat cgcttcagca atagcagaac gatgataaat atcaatcgta
    13681 cggtacccat aaaatgtata taaacagcta aatataaaag ccgcatcgat tctttttaaa
    13741 aattttagtc cataatgaaa catcagcatg atagtacaaa cattcaatag ccaaacatat
    13801 aagatataac taacgattaa attattactt atccaataaa aaatgactgc cggaaaaaag
    13861 gtcaagtagg gataaaaata attcactccg ctcccataat gattaaacgt cgtaaaattg
    13921 attggaccag aaaaaattga agataaccct ttgactctag caaaatggaa ggcaatatcc
    13981 cccgatgtag aaatagtatg aacatttcta aaataattga ttgaataaag tccagcaata
    14041 attgctagga gaatggacaa tattattttt ttctttactt gcattactta attatatact
    14101 cctttcatgg attgctttat ctagtataac ttaaatttta aataaatcgt tatttatttt
    14161 tactctcact taaaaaagca ctaaaattat aagagaggga ggtaatggtc tgaacaccaa
    14221 gaattgttcc aacatcgaat tgcttaacta atgagttcaa agcttaatta tgtggctctt
    14281 atatttaccg agcgtggatt gcgatctctt tagcgaaaca aacatctttc ataaaaaaaa
    14341 cagccatatc cgctttcttg gatatgacta tttactacta ctttactatc tttcattctt
    14401 cttgtctcac ttatgataag gcgctgggta tcatgagtga atgatattgc tgaatacaaa
    14461 tagtccgacc acattaagtt gatcggactt cataagcatt ttattgacta atactttttt
    14521 gcttaagaat tgattctaac atcttttgct aaagttaagc atcctatagt tcctgcatta
    14581 tctgctaact taggtgtgac aatgtattct tcgatatttg gcgtatcgac atagccgtta
    14641 attagttcta aaaaacgtct ttgtactttc tttttcagat gttcttgttg catgacacca
    14701 ccaccaaaaa ttataatatc tggtgaaagc atcagggtcg tattacaggc acattgtgca
    14761 atataatccg cctcgatttc ccagaacgga tcttctatag aaagatcttg tcccttggtt
    14821 cccgtacgca tctcgatagc gggtccagat gccaaccctt cgagacaatc atgatgaaaa
    14881 ggacaagtac cagagaaagt atctcctgaa tgtctcttaa ctaacgtatg ccccatttct
    14941 ggatggctaa acccttcaac aaaaatccca tcttgtatag ctcctccacc aattccagtt
    15001 ccaacagtgt aataaacaac actggataaa ccttttccat gacctgaaac atactccccg
    15061 taacaagcag cattcacatc ggttgtccag gcaattggaa tttcgaaatg cttattcaac
    15121 gttccaacaa aatcaaaatt tttccaggca gtttttggag tagaggtgat atgtccatag
    15181 gtctttgatt cacgatggat atcaatcggt ccaaatgacc ctactccaat gctttctaat
    15241 tgttctttat agtgattaaa gaaatcaatt accaaactca ttgtttcatt cggtgtagtt
    15301 gtaggaaaac tcactctttc taaaaccttt aaatcatcat tgccaatggc acaaacaaat
    15361 ttagtcccac ctgcttctat tgagccatac atttcttact ccaccgtcct tttatctagg
    15421 aattcgttct tccctgtcta atagtttttc gaaaaactca tgtggttcct tttggtacca
    15481 ataggcaaca gaagaaatat cgtcttgacg ctcataaagc ttgatgtcat catttcctag
    15541 ggtttggaaa gtaacacgta aattttcttt gaaactaatg gggtcgggta aatgccagcg
    15601 gtacaaccca tgcatcggta aagcatcatc gccaaaacca tgaactggat ttggattagg
    15661 ttttccagca ctaaaataat cccgggtgtg atctctttta gattgaaaag gatagcccat
    15721 aaatagcgta ttaaaatttt gagcatatgc cctttctcca aagttctttt tatggaaagc
    15781 ccaagcgccg ccaaaataat cttctgctcc tgtagatgtt attgtaggga aatcttcatc
    15841 tccatctata taaaacttaa attctccttc cccccaccag tatctttcca atgcgcacaa
    15901 agcaaagtag gttcctacat aatacccagt gcctttgatt ccatcaataa gggtgtaatc
    15961 ttttcctttt gtcgtgatgg gttcacggtt ccatttagca tgaaaataca tcgcatcatc
    16021 cggtacttca gtcaatgcat aattaaatgt ataaaaaatg tgcttaataa actcaggatg
    16081 ttcattcgtt aaagtaatct tagctttttt tcgaaatggc atctcaaaat agcaattcat
    16141 ccctgatgtt ggattcacta cgattggtaa ggaattcact tcgcatcttg tcccaaaccc
    16201 attacaaaaa aaatctccta atggactttc tacagaagga gtggattcat catcccaata
    16261 aatacgcaaa attaaatcac gtaagacgaa actcccagcg attgttttgt ctgtcactgt
    16321 catccaaaaa tgacgtaaaa ttccagggcc ttccatttct gctaaagtaa ttgtctctcc
    16381 agcatttatc ggaacagaag gtgacccttt tctcccaatt cctagatgac tcgctgtcat
    16441 tgccgctttc cctttttcac catttttatt ttctggtgaa atagttctac tttcctctcc
    16501 cttgtggagc catatattat ttaaacaatt cattttattc gtcctctatc ctttcttcac
    16561 ttttttgatt attcatatag atgatttgtt gttgtgcctc cgcaataatt gctccaatat
    16621 ctaaattatc atttcctaac tgcaaagcga ttgacattgc caagggaaga ttcattcctg
    16681 caattacgtg cactctgtca gaaatatagg taaaaaactt ttgatttaca cttcctccag
    16741 ccatgtcagt taaaacaatt atttcgtctg tagtatccac taactcttta atttgttcat
    16801 ctatatcatc aatttcttcg acatatgcac ataagctact aatttgatta tgcatacctg
    16861 ttaaaaactc tagtgtctct ttaaaaccct cagctagtat tgaatggcta gcaatgatca
    16921 atcttctcat aattcaaatc cttttccttt acgctaatat tccaaatgca gccataacca
    16981 tcgcaaaaac aataacgagt agaatcaaaa tggtcatact gatttttttc ttactgagta
    17041 gataatatgc tgcagcagta ataattactg gaattaatgt tggtaaaatt ttgtccaaca
    17101 ttggttggat tttcatacta acttcaccaa aagtgaattt aagtggcgtt gaaacactga
    17161 taactgaagc aattaatgat ccaactactg ttagccccaa tactgaagca gcttcagtta
    17221 aataattaat cttttcaccg tattcagtaa caatcttcat tccctgctta taaccaaatt
    17281 caaagcctct cattcggaaa aagaagatta ccatgattaa aatgaaccat aaaaagattc
    17341 ctacaggatt attttctaaa gccatataag ccgcaattga tcccatgatg gttgggatca
    17401 tcgtcatcaa aagagagtcc ccaataccag caattggacc catcgtacca actttaaagt
    17461 cattaatcgc atcttttgct tctaatcctt gcttttcctc cattgcaaca caagcaccta
    17521 aaataatggc tgccagccaa ggctgtgtat tgtaatactg aaagtgatta tttaaagctt
    17581 cgatgtattc atcatcatct ttgtataatt ttcttaaaat aggtgacaat gcgtaagtca
    17641 cagatgcacc ttgctgtgtt tgataattaa aggtacaaac tgacatcaac caacgatagt
    17701 tcgctttcct aagatccttt ttcgttactt gatatttttc gctcatttta ttcatcctcc
    17761 ccaataaacc caacatcaga agctcccgca gaagcagtga tttgtgcatc tttttcagct
    17821 ctatgataca cattaaatgc taaagcgaat cctatgatcg ccgctccaat aataggtacc
    17881 ttcaaaaaag cggctaagaa aaatccaaca agtaaataac taatgtatcg acctgtaggc
    17941 ataaagcgta acaacatcgc aataccaaca gcaggcaaca tttttccggc taatgttagc
    18001 ccatccataa accaattagg taaaacatcc aaaacgtaat taacagcaga ctgtcctaaa
    18061 gtaacggcaa taaatactgg aattgctgca gataaaccaa agaaaattgg ccccaaccac
    18121 aaaacactat tcattttctt aaattctcgt ttattcgcat attcctgtga tttgcgaaca
    18181 acaaaaccat ttaagatttt gacaattaca tctagttgca cccctaacat acctacaggt
    18241 agtcctattg ctaatccggc ttctactcca agctggctac caaatgccgt tgcaataatt
    18301 gcgcacgttc catagtccgg tacagatgag ccaccaaaac cggcaactcc taatgacatc
    18361 aattgaactg taccgccaac tatcaaacct gtttttatat cacccatcaa aattcctgtg
    18421 aataatcccc aaaaaactgc gtaatttaca aagatcatcg gaatcccata ataatcaaca
    18481 tgtttaataa atgctaatat agtcagcata ataatttgaa aaatagtaaa atgcattatc
    18541 cttactcctt tatcctaatt ttgattgaat ttcctgtgcc ttatccgccg gaacaaattg
    18601 tgtaacaatt tctacaccag aatccaacaa ttttttatac gtgctgatat tttcatctga
    18661 tgcataggct ctagaagata gctgtaatgc attatcttta acaacagtac cgccaacaat
    18721 tagtcggtca attctaatac cgttatctac taaatgaagg attgtttccg gctctttcac
    18781 gatgacaaat actttttcct gatcgtattt ccccttttta aaattcgcaa tcgctgtttc
    18841 ttcagtgata attgatacag ccattccagc aggtctagct aaacgcatac ttgatttttg
    18901 gatgtcgtta tttgcgacag aatcatcgat caccatcact ctgtttgctt tagacattgg
    18961 tgcccattgc gtgacaataa tcccatgcaa taaacggtta tcaactctcg acataacaat
    19021 actcataaat acttcctcct ttatctttca ttttcttaca agcaattacc atgccaaaac
    19081 aaaaagaact tgataaatca agctcttttt acataatcat aaacgtattt aacctcatga
    19141 atcgggatgt cgacactata ataatgttca acgacactga aagattgctt aaaatgtgtc
    19201 tgaaattttt gaaattcctc actcgtttca ttgaaataaa tttcatcttc caaagtattt
    19261 tgttttacta atcgttcaat taagcaacta atgtgaacat ataatccgaa acacgtatta
    19321 ttatcaaatg aaattcctag atcattttgt aagatgtata tagcatctga aacccgttct
    19381 aataatttag tcggatttaa tatggtcaat tgctccatta aattcgttag actaaaattc
    19441 ttcagaatat tattgttcaa aactttcagt tcattatcat taaagtgtct attcaattga
    19501 ttggagaatt tacttatatt cattcctaaa atcatatctt caattgaaaa gaattctaca
    19561 tcttctagat gtggatttag tgttccaaca ataaaaagaa tattgttctc tttacgaagc
    19621 tccgataaat agttttcatt cactaaagag taatagtcac acgtttctat gacaagatca
    19681 gtatcccttg gaaagctatc ttcaagtatc ctttttaatt taaacgaagt tcctaatccg
    19741 cttgcacaag aacagacaat catatccttc ttaatatttg atgattcata aatataatcc
    19801 acattttgat tttcttttac ttgttcaaga atctgtttaa gcggtaaatc taataatatc
    19861 tgatttgcaa catcaatagc cattcttgtt gaaacattgt ttagtagtcc gaattttttt
    19921 tgagcgtcta gttccaaatt tagataaatt ttctccagtg aacccatatc aacaagtaaa
    19981 ataatttctt catatccggt acactcttgt aagtatctat taattttgtc tgcaatctca
    20041 ctacttgaag tcattagtgg catatcaatg gcgtcgtata tatatctctc aacgatccta
    20101 ttagcagtac ttgctataca ggttgccgtt agatctccat gagccaaaat cagtgctaaa
    20161 cgtttttgct gaaattcttt actacacatt aacttaaata aaataaccaa aacatttttt
    20221 tgaatttttg ttaaataaat atcccctatt tgaataaaac gattgactaa ttgaacttct
    20281 cgactacacc aactattaat atcattgatg aaggaatata atttatcgtc cgatgttaat
    20341 tggatttgat aaatccaaga attcaaaaag atagacgtta tttgaagata ataatagtca
    20401 aattctattt gaaaatctct ctctatttcc ttaacatact gtctaaatcg aatctcttga
    20461 taggtgggat atgttaaagc tgaattattt tggatatcaa cattcttttg tctaaaatat
    20521 ctatcatatt tctcaaaaag ctgctgctta tcagtgtctt tcttccacgt ttgataaaga
    20581 tactctataa gttcgttgat attaaaaact tcgtctactt tttccaaatc atccatttga
    20641 atatatttta attcattctg tcttttcata accttcatgc cgttgaaatt cacccattgt
    20701 ggtaaatgat acatctgaat ataaagttct tccaaatcat ctaagaaata aaaggcattg
    20761 gcacaggtca attgaatgat atttttcaaa ttgccaacat tttcactaaa gcgatagttt
    20821 aataaaaaat ctaataattg ttgagatatc agtattttct ttgctagtct ttcttcttct
    20881 gatttaaaaa atatcttgat taactgtttt ctttcataaa gagaacgact gtctaatgtt
    20941 ggaagtgtta gctttacagg tattcttctc aacaaagttg ataatagttt atcctcaggt
    21001 ggttctgatg ttgcaaatat aatccagcaa cttgatgtgt accagttttc attatcaccc
    21061 atccgatgaa atttcctcgt atccataaac tgaaaaagtt tctcctgaca ttcattgctc
    21121 aatgcatgaa tttcatctaa aaataagact ccattattag ctaattctgc taaacccttt
    21181 cttccatctt cggctcctgt atatgcacct tttacatgcc caaaaaaatt ggacaagaaa
    21241 agttctggat tattggcata ttcactacaa ttaactgaaa tgaaagatgc cttctcttct
    21301 atataattat tggccaacaa atccttatac acataatttg ctaaatagct ttttccagtt
    21361 ccagtctcgc catgaagtaa aatgggtaag ccatttggcg gatagtagat tgctgcttta
    21421 atttgagcaa ttacatttcg cagacttcct tgacttccga taaccctttc tattccaacc
    21481 ctaaaagagc tatcatacca tttttccgct tcctctgaag agctaaaaat ttgttgattt
    21541 ggaactttct ccggtaaaga aaagaagatt actggacgag tattgatttt tccaaattct
    21601 ccatctttta cgaattcatt caaatattga gagacaatat tacgactaac atttaatttt
    21661 tcagatattt tctgtgctgt attgttcccc catttatttt taatctcaga gttctctatg
    21721 acataattga caatgcgttc ttttaattct tccatcacag cacctcctcg acactattcg
    21781 aattttgccg acagtatttt tccataaata tgacttgcta aaaaggcttt gtttagatca
    21841 ttcaattgga acgttgcttg ttttgcttga tccgctaaga cgttgaaaag atactctggc
    21901 gaaatcgcat accccaaaat atcaacgatt gttgcaatca gatcttcttt tgattcttca
    21961 tctgaaagta attcacgata caacatcgtt tgtttgctta ctgtgtcata ttcctctaag
    22021 gattcatctg ctaaaagaac cacttgttcc aacaaacggt cggataaata tttatagaaa
    22081 atcagcccca ataaataatt tttatattct gacgcatcca ttttactacg gagattatct
    22141 gccgcactaa ataacttctg atttaattct gcacccaaaa agatacactc ctatctctta
    22201 tttaaagttg ctatataccc tcttatttta gcatactcag ttttagaaaa agcaaaaaaa
    22261 taaagaaact tattcttgat aacaagctac gtgacgtata tccctaacac aaaaatagcc
    22321 atatcctttg gtttggatac ggctatttga tattactcat tcaattatca aatcacagta
    22381 ggtgtgaatc tcatcgggat cggcaatatc tacttctgat taggatcaaa ggtgattttc
    22441 tcaataaagg tgtgatacaa agctttaact tgcttcttct cactctggat aagaaagcaa
    22501 tccaaactag tcaatatctg ttggacatct ttgacttgaa tcggttcccc ttgttgttga
    22561 aagatcccta agatttcatt ctctcgaatt tgtaactgtc ttcgtttttc agtcaattca
    22621 tttaaacgat cttttaacat cggaaacaat tcgggactat cttccaaagc agcttcctgt
    22681 ttttgctcta atagttagat tttgcgtacc attttcttct tttattttcc ttcgattgct
    22741 gattttaata tagtctaaag gaaatttata tttattgtat tctttataac ttcaagagaa
    22801 cttcgtttga gtattactgt atttttttaa ttccataaga aaattagtta ttacctgcca
    22861 cctaatcagc aaatctgaac ctgagtcaat ataattaata ttattttcca tctccaacat
    22921 tgtaagtact gttggtgtta atatagggac tttgtacaat tgtatttttt tgattttatc
    22981 atctgcacaa aggagatttt ttaaatctaa tccttctttt atttcaaaag ttgaattttt
    23041 taaatctata agagtaaaac caattccttc atactgaatt tctgaaaatc gaatttttct
    23101 cccagttgat agatcaaggg gcagaaaacc ttttattaca ttgtgagtgt caccatcatt
    23161 tacaatgtca ttaggaattt tgattttaga attctgtgga gcacctattg gaagataata
    23221 attcattata attttgtagt cttcatgagg aaataaagta cttttaggat tgctaagata
    23281 ttctcgtacc gaatctaaga atggcttatc cattgaatct tcatccccat ttaaactaaa
    23341 aaacattcct acaattgctt ttgcaactct aagtgaattc attttcttta ttgaatgtgt
    23401 taaatcagac ttaccattct ttaaacttgt attgttataa aggaaatttt tattgtcttc
    23461 tgcaaatcta atatattcct caacatactc actaccaaaa aaactattac atttactaca
    23521 taacgtattg gaatggcaac agtttttttg acaaatttta taaggtgcag aacttctttc
    23581 cgtatgctat tccgattgtc cttgacaatg agcctcctcg gatgtgacga tcttcggcag
    23641 gagctaacag ttaaagttag actgcctcgc tagcgttagc acatccgagc tcattatcaa
    23701 ggattcgctg cgccaat
//
LOCUS       DADVXV010000042        22860 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.043, whole genome shotgun sequence.
ACCESSION   DADVXV010000042 DADVXV010000000
VERSION     DADVXV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.043"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            114..230
                     /locus_tag="KB969_001553"
     CDS             114..230
                     /locus_tag="KB969_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBB6869541.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(285..1967)
                     /gene="recN"
                     /locus_tag="KB969_001554"
     CDS             complement(285..1967)
                     /gene="recN"
                     /locus_tag="KB969_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBB6869542.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(1985..2434)
                     /locus_tag="KB969_001555"
     CDS             complement(1985..2434)
                     /locus_tag="KB969_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBB6869543.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(2541..3359)
                     /locus_tag="KB969_001556"
     CDS             complement(2541..3359)
                     /locus_tag="KB969_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBB6869544.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(3368..4258)
                     /locus_tag="KB969_001557"
     CDS             complement(3368..4258)
                     /locus_tag="KB969_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6869545.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(4260..4484)
                     /locus_tag="KB969_001558"
     CDS             complement(4260..4484)
                     /locus_tag="KB969_001558"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBB6869546.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(4489..5826)
                     /locus_tag="KB969_001559"
     CDS             complement(4489..5826)
                     /locus_tag="KB969_001559"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBB6869547.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(5827..6681)
                     /locus_tag="KB969_001560"
     CDS             complement(5827..6681)
                     /locus_tag="KB969_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBB6869548.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(6778..7227)
                     /gene="nusB"
                     /locus_tag="KB969_001561"
     CDS             complement(6778..7227)
                     /gene="nusB"
                     /locus_tag="KB969_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBB6869549.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(7220..7645)
                     /locus_tag="KB969_001562"
     CDS             complement(7220..7645)
                     /locus_tag="KB969_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6869550.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(7891..8955)
                     /locus_tag="KB969_001563"
     CDS             complement(7891..8955)
                     /locus_tag="KB969_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBB6869551.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(9127..9372)
                     /locus_tag="KB969_001564"
     CDS             complement(9127..9372)
                     /locus_tag="KB969_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6869552.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(9511..9885)
                     /locus_tag="KB969_001565"
     CDS             complement(9511..9885)
                     /locus_tag="KB969_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBB6869553.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(9968..10882)
                     /locus_tag="KB969_001566"
     CDS             complement(9968..10882)
                     /locus_tag="KB969_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBB6869554.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(10903..11706)
                     /locus_tag="KB969_001567"
     CDS             complement(10903..11706)
                     /locus_tag="KB969_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBB6869555.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(11739..12728)
                     /gene="manX"
                     /locus_tag="KB969_001568"
     CDS             complement(11739..12728)
                     /gene="manX"
                     /locus_tag="KB969_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBB6869556.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(12831..13322)
                     /locus_tag="KB969_001569"
     CDS             complement(12831..13322)
                     /locus_tag="KB969_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869557.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(13513..16320)
                     /locus_tag="KB969_001570"
     CDS             complement(13513..16320)
                     /locus_tag="KB969_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6869558.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            complement(16754..17047)
                     /gene="rpmA"
                     /locus_tag="KB969_001571"
     CDS             complement(16754..17047)
                     /gene="rpmA"
                     /locus_tag="KB969_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBB6869559.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(17060..17404)
                     /locus_tag="KB969_001572"
     CDS             complement(17060..17404)
                     /locus_tag="KB969_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBB6869560.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(17431..17739)
                     /gene="rplU"
                     /locus_tag="KB969_001573"
     CDS             complement(17431..17739)
                     /gene="rplU"
                     /locus_tag="KB969_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBB6869561.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     misc_feature    complement(17759..17835)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            18021..18662
                     /locus_tag="KB969_001574"
     CDS             18021..18662
                     /locus_tag="KB969_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBB6869562.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            complement(18724..20355)
                     /locus_tag="KB969_001575"
     CDS             complement(18724..20355)
                     /locus_tag="KB969_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBB6869563.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQFPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(20478..20837)
                     /locus_tag="KB969_001576"
     CDS             complement(20478..20837)
                     /locus_tag="KB969_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBB6869564.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            complement(20996..21069)
                     /locus_tag="KB969_001577"
     tRNA            complement(20996..21069)
                     /locus_tag="KB969_001577"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21033..21035),aa:Arg,seq:tct)
     gene            complement(21378..22061)
                     /locus_tag="KB969_001578"
     CDS             complement(21378..22061)
                     /locus_tag="KB969_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBB6869565.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            complement(22189..22707)
                     /locus_tag="KB969_001579"
     CDS             complement(22189..22707)
                     /locus_tag="KB969_001579"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBB6869566.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
BASE COUNT         6578 a         5037 c         3793 g         7452 t
ORIGIN      
        1 tcgtaactac ctattattta aaaaaaggga agtttttata aaaaagccct cttgtggaaa
       61 tggaaaaaag attgtacact tgaatcaact aattaatgac gaggttgaaa acaatgcgtg
      121 aaaaaaaaca aacaagtact tttgctaaag taacaaaatt tgtcatttgg acaatgctga
      181 ttttaacgat tggatctgtt gtattgactg ctgtaatgag tgtcatgtaa aaataaaata
      241 tagctatcag ctgctgaaaa ggacctgaac cactgcgagg tggctcaggt cctttttgcg
      301 agtttcaata gttcttttgc atgttcgagt gtgagttttg taatctcact tccagccagc
      361 atacgtgcaa tttcttcttc tctttctttt gttttcaact ctgaaacaga agtttgcgta
      421 cgtccatcaa tcactgcttt cacaatataa tattgatagt cggcgactgc agcaacttga
      481 ggcagatgag tgatgcacaa aacttgagag tatttcgata tttgagaaat tttatctgcg
      541 atggcctgtg caactcttcc gctcacacct gtatccactt catcaaaaat aatacttgtc
      601 acaccttgct cagaagaaaa aatagttttc aaagcaagca acatccgaga cagttcgcca
      661 ccagaagcga ctttcaccaa aggcttcagt ggctctcctg gattggtcgt aatgtaaaat
      721 tcgatttggt caaatccatc atgattcaat tgtctatttt cttcttttaa gaaacgtacc
      781 tcaaactcag tgttttccat atacagactt ttcaattcat gcagaatgga tttttccaat
      841 tcttttgcga tttttttacg cgcttcatga agatctgcgg cttgttgctg aagtagaagc
      901 tctttttgct ctagttcctc tttcattttg tccaattgac cttctgaaaa atcagaagaa
      961 gctagctctt cggtgatttc gtcatagtaa gccaatattg actcaatgga ttcgccgtat
     1021 ttacgtttca actgtcggat taattctaaa cgttgcgtaa cttcttctaa acgactctca
     1081 tctaactcca ataaatcaat ctgacgactc atatcgccga ttgcatcttg cagcaaatag
     1141 taagcacttt ggatattttc ataaattgct tcatactcca catctagatg ggcgatccct
     1201 tgcagttctg aaacggccaa gccaacacca tctacactgt tttgttcatt attcgtcagt
     1261 gctccgtaac ctgcagctaa tccatcagca attttttgat aattgctaag tttttctctt
     1321 tcttctttta atttctcttc ttctccgact tgcaaatcag cagcagctat ttcttcttgc
     1381 tggaaatgga gcatatctat tctctgaaca taggattttt cattttgctg cacttttcgt
     1441 accctttttt ccagctcacg ataagagata tattcttgct gataactctt tttcttctgt
     1501 tggaaagcta catctccaaa acgatccaat aaagcaagat gtgattcagg ctggagcagt
     1561 tcctgatgtt cgttttgtcc ttggatatct actaaataac tgccgattct tctcagatta
     1621 gctaatgtga taatatgacc attcactcga caaacatttt ttccagttaa ggacatatcc
     1681 cgtcgaacaa tcagattgtc ctcatctgtt tcgatcccta attcaaccat cagttcagag
     1741 aatccttctt gttttggtag ttcaaacaac ccttcaagca cacatttttc tgctccttga
     1801 cgtatataat cgcttgaacc tcttcctcct gctaacagac ctaaagcatc gataataatg
     1861 gatttacccg caccagtctc tccggtcagc gcggtcattc cttcgtgaaa agaaagccgc
     1921 aattccggaa taatcgcaaa gttagtaata ctgatttctt gtagcatcac attcgctcct
     1981 caacttaaag gtaatgcagg aagtctttct tcaataaaac tgcctggtct tcagttcgtg
     2041 taatcatcaa aacattatcg tcatcattga taatcgaaaa taattctttc ttgtaacgtt
     2101 tatcaatcaa atttgctgct gccgaagcat ttcccggcaa tgttttcaaa ataacaaatt
     2161 tttccatttg gtcaactgcc acgaaagcgt cttttaatag tttttccaat ttagtattta
     2221 catcttcgtt tgtttcagct ggtatgctat aacggtagcc gccatctgaa gccggtacct
     2281 tgatcagttt cagttccttt atatctctgg aaatcgtagc ttgagtaaca gatattcctt
     2341 tgcttttcag gatttcaaca aattcttcct gctttcggat atcttgctca ctcaacaatc
     2401 gagtaatcaa acgatgccga tctttttttc tcattacgtc ttcgctcctt agcatattct
     2461 tcttaatcaa tgatagctta tttccttggt ataataaaga agaatccgca tacttctcac
     2521 ttgattttca cagttacaat ttatttatgg tcaaactgtt cgtgtgcatt tgaaaccact
     2581 tctgccatat taatagctga attgattgtt ccgctttcgg gtactttcct caagtgagcc
     2641 aagaactcga tatttccttc tccccccgtg atcggagaat aacttaattc cagcacatca
     2701 tatccacctt gtgccgcaaa tgacaaaatg tcttctaaaa ctttttgatg ggtctgaggg
     2761 tcacgaacaa ttccgttttt ccctacagct tctctgcctg cttcgaattg gggtttgatt
     2821 aaagcaatca cttctccctc ttcttttaaa atagcatgta atggaggcag catcagtttt
     2881 agtgaaataa aagaaacatc gataacagca acttctggaa ttcctaaggt aaagtcttcg
     2941 ggttttgcat aacgaaaatt cactctttcc attacgacga ctctaggatc ttgtcttatt
     3001 ttccaagcta gctgattgta gccaacgtct aaagcataac tcatttttgc gccattttgc
     3061 aaagctgcat cagtaaatcc gccagtggat gcaccaatat ctaacaatgt ttttccttca
     3121 acagatagat caaatgcttt gagtgctttt tctaatttta atccccctcg agaaacataa
     3181 ggaagttttt tacctttgac tcttaattca ctactcactg gaattttttc tcccggttta
     3241 tcaaaccgct cgtttttttc gttgtaaatc aaaccagcca tcactgaacg tttggcttgt
     3301 tctcttgttt caaataatcc ttgtttgacc gctaatacat ctacgcgttc tttttccatt
     3361 ctttccctca tttctccaca tcaaattgct tgatcatctg gcgcatcagc ccgccatcaa
     3421 aagaaaaaac gtcctcttct aatttgtcta tgatcttgtt ggcggataac agctcaatct
     3481 ccaacgcctc acgtgtcttt tctaggccta ataaacgcgg gtaagtattt ttttccatac
     3541 gttcatcttt accagctgtt ttccctaatg ttttcgttgt accaatcaca tcgagtagat
     3601 catctcttat ctgaaaagct aaacctaaat gttcggctaa tcgttgaagt agcaataaga
     3661 tttcttcagg ttgcttcgct aatatgccac cagccagcaa ggcataacga atcaaatgcc
     3721 ctgtctttct ttcatgaata aatgctaatt cttctaaaga aagctttttc gattcgccct
     3781 cgatatctgc agcttgccca gcaaccatac cttgtgatcc cgcacaaaca gctaattgct
     3841 gaagcagcag aagcttagga gaattaccta agtgtgccat actgattagc tggaatgctc
     3901 ctgtaagcaa accatctccg gccaatatag ctaatgcttc gccgaatact ttatgattgg
     3961 taggttttcc tctacgaaga tcatcattgt ccatcgcagg caaatcatcg tggatcaagg
     4021 aatacgtatg caccatttct aaagcagctg ctacttgata gacgggaaca tcaataggct
     4081 catcaaagga agcaacggcc gttaaaagta ataagggacg tattcttttc ccgcctgctt
     4141 tcactgaata actcatcgca tcatagagtc ctctatccgt tgtatgctca tctaaaaaag
     4201 acaagatttc tttttctaca gcaggtagat gaatagctga aaagtcagtt aatctcatct
     4261 cagctttcct cgtttccgtc aaaatcaact tcttcatttg attctgtcat cattttcgtc
     4321 aaggtctctt ctgctttagc taatgtatct tggcaatgtt tgcttaattc cattcctcgt
     4381 ttaaacgaat ctagagctga ttctaatgga acgtctcctt gttctaactg catgacaatt
     4441 ttttctaatt cttgcagtga ctcttcaaaa gttggatttt ccatattttt attctccttt
     4501 gtctatctct tgtacttgtc ctttaacgat tccatcttga taatggatcg tcagcaaatc
     4561 cccttgatga atctcggtga cactttttac tacttgatca tttaacgtcg tatagctgta
     4621 gcctcttccc atgattttca atggactcaa caaatcaaga gattgaacag cttgagcaaa
     4681 acgctgctgc tgttgtttca tatattgttg gattttctct tctaagcgtt tttctagata
     4741 agcagtttct tggcgagctg ctttaactcg ataaagcgga gccacttgtt ccaattggtg
     4801 gcttaatgcg atcgtttgtt tttctttcgc atgataaatt tgctgtgtag cttgatataa
     4861 tcgctgtttc aactggtcta atttgatggt ctgaccttca tacaatcttt caggctgccg
     4921 aaatacatag gaacgtcgag cacgctcgaa ccgttcttgt ttgcgctgga tctggcgtac
     4981 aaacgcctgc tgcaatctag cttgccgttc ttgaatgcgc atcaactctt ctgacaaaac
     5041 aggaacagct aattctgcag ctgctgttgg agtggcagcc cgaacatctg ctactaaatc
     5101 agcgatcgtg gtatctgttt catgtcctac agatgaaatc accggcgtat tagcttgata
     5161 aatcgcccga gcaacccgct cttcattaaa cggccataaa tcctcaatcg aaccaccccc
     5221 acgaccgatg atcattgtat cgaaattgcc catctcttct actctctgga tattcctgac
     5281 aacattgtcc gctgcttggt ttccttgtac aactgttggg aacaaaacca attggacaat
     5341 tggatatctt cttttcaccg tcgtgatgat atcgcggata accgctccgc ttggactggt
     5401 aaggaccgcg attcgctttg ggaaacgtgg cagcattttt ttaggccctt gaaaaaggcc
     5461 ttccttcatc agcttttctt ttcgttcttc caattcttga tataaagcac ctattccatc
     5521 aggctccatg tgctctacat agatttgata agaacctccc gcttcatata atgaaatacg
     5581 cccaacgaca aggactttca ttccttcttt tggctggaat cgtaattttt ggaatgctcc
     5641 tttgaacata atagcagata tttttgcatg gtcatctttt aagctgaaat attgatgggc
     5701 attggcacgt aaacggaaat tcgatatttc gcctgttaaa tatacgcgtt ctaaataagg
     5761 atcggcatca aattttcttt tcaaatactt cgttaatgta gtgacagtta aatattcttg
     5821 tgccatctat tcacctgctc caaaagcttc ggcagatttt acggtttgat acatcagcat
     5881 cgtgatagtc attggcccta caccctttgg cacaggagtg atccagcctg caataggctc
     5941 cacttcatca aatttcacat caccgatcag cttaccgtta gcatcacgat tcatccctac
     6001 atctatcact acagcacctg gttttacgaa ttcttttgtg acaaaatgtc cacgtcctat
     6061 tgctacgact aaaatatctg cttcttgtgc cagttcagcc agattttcgg ttttagaatg
     6121 agcaacagta acagttgcat ctgccatcaa gagtagctga gccatcggtt taccgacgat
     6181 attgcttcgt ccgataacta ctgctcgttt acccgccgga tcgatagaat aagcttcaaa
     6241 cattttcatg atgccgtatg gagtacaagg aatcttgtcc ggtttacccg caaggagtct
     6301 gcctaaattc atcggatgaa aaccgtctac gtctttttca gggcggatag ctaacaggat
     6361 cttttcttca tctatatgct ttggcaatgg taattggacc aatataccat gaaaactagg
     6421 atcttgattg tatttttcaa tttctgcaag tagttcgtct tcagaaatcg tctcaggata
     6481 acgctctacc aatgaatgga ttccgatttc ttttgctaca cgttctttat ttcttacata
     6541 gatttggctg gctggatttt cccctaccaa taaaacgact aatccgggat ggataccatt
     6601 atctttcaat ttttggattt tttcagcaat ctctgcctgc attttttcag ctaattcttt
     6661 tccgttaatc aattctgcca tctaaccact cccagatatt ttttgtgttt tcattctacc
     6721 atagaatttt cccgatttat aacaggttta tgatgattca tagaaaaaag ctaggactta
     6781 cgccccagct tctaattctt tcaatacatt ggataaaaca ccgttgacga atttacgtga
     6841 acggtcatca ctaaatgttt ttgccaactc gattgcttca tttaaagcaa cagccgctgg
     6901 tacatctgtc acataagtca tttcaaaaat cgcgatacgc aagatcacca aatccatttt
     6961 tgagatccga ttgatgtgcc aattgttttt taaatgtttt tcaatcactt tatccaattc
     7021 atcttttttt gcacagacac cgccaactag cgtatcaaga taaacaggaa caaactctga
     7081 ttcatcttcg ttgatcatgt cgcggtggtc taattcgatt gcgttgaaaa tcgcatcttc
     7141 ttttgttagg tctgcattga agtctaatgg aaataaagcc tgcaatgcca tttcccgaat
     7201 ctcgtgtctt gataattctt tattcattct cttcctcttc gtcttcaaaa agttcttcga
     7261 ttgttggttg ttctaatttt tcaggaacaa cagctactac atggatattg acttcagata
     7321 aatcgatatc cgtcatgaaa aggacttgct ggctgacccg ttcctgcatt tccattgcta
     7381 ctttaggaac tgaaacacca tattctagat aacagtaaag atctactttc aagccatctt
     7441 cctcgtttgc taagtaaaca ccttttccgt gagctgcacg tcctaataat tcagtgacat
     7501 tgctggcaaa agttccgcgc attccgtata cgccttctac tttagaagct gcaatcccga
     7561 taattacttc gatgacttca ggagcgatca cgatctctcc taaatcttgg tttgcgttta
     7621 aaatcaaatt tttttcatct gccatttatt tattcctccc tttgcctaag cacgagatac
     7681 atccgaattc tctatgatgc ggcatagtga tcacgtggta agaaaactgc cgccgatcag
     7741 ctgcaaactg ctatgaattg gagaaaacac ccaactttat tatctcttac agcttaaaag
     7801 ttcttctata gtgtatcatt aaatcgagtg attttctata acaaagtctg tgaacactga
     7861 tttttacgct tacttcttct attgatgaaa ctataagatg atcaattctt ttggtgaacg
     7921 agtcaacaca cgatttccat cttctgtgat caacaagtca tcctcaatac gtactccacc
     7981 gattcctggt aagtagatcc ctggttcatc agtgatcaca tttcctggta caaattgctt
     8041 ttctgcacga gaagaaacgt ttggtccttc gtggatctct aaaccgatcc catgtcctgt
     8101 agaatgtcca aatgcttccc cgtaaccatg ttttgaaata taatctctag caactgcatc
     8161 taattggaca ccagtcattc ctggttttgc agcatcaata actgctaatt gagcatctaa
     8221 gactatttga taaatttctt ttaatttttc cccaggatca ccaatagcga atgtacgtgt
     8281 catatcggaa acgtaccctt cgtaatagca accaaagtcc aatgtgatca agtcaccttg
     8341 ttcgatgatt tttttgcttg ctacaccatg cggcatagcc gaacgcaatc cgctagcaac
     8401 gatcgtatca aaagaaacac ctgaagcgcc aagagaacgc atataaaagt ctagttgatt
     8461 tgcgacttca atctcagtca tgcccggttg gatcattttc aggatgtgat catatgccat
     8521 atccgcaata tgacatgctt tttcgataat agcgatttct tcttcatctt tcacttctct
     8581 gagttcttcg atcatctgtg aaacaggtac taattccgca tcgatgattt cttctaaaac
     8641 cgaatattct aaaaatgaga ctgttgtttc ctcaaaagct aatgagtgca gttcttcttt
     8701 gcgtactaag tttgctacct catcaaaaat aggtccgaca tttttaataa tttcaaaccc
     8761 ttgagcctgc gctgccgcct gctcggtata acgaaaatca gtaataaaaa atgctttttc
     8821 caaagtaata acagctaatc ctgtcgtacc tgtaaagttc gttaagtaac gaagattgta
     8881 cggactggta accaaaaatg aatccaaatt ttcttcttgc atttttttgc gcaatttttc
     8941 tacacgtagc atcataatga aactccctct ttctttgcac gcttttttcc attatagcaa
     9001 acttttcttc gtacacgaca gttaaataaa aatttccgga aaacttcttt ttattttaaa
     9061 taaataaagc caaaaaggag tcacagtctc gctgcaactc cttttagttt actattttgt
     9121 aaaaacttat gatcgttttc caaagaaaaa tgagacaact gctaccaaaa tcactgcgcc
     9181 taaaatagat ggaataagtg ccatacctgc agcttttggt ccccattcgc cgaaaatcgc
     9241 ttgtccaata cttgaaccga ctagtccagc aatgatattc gttacacagc ccatcgaatt
     9301 tcctttactg gtgatcgcac ctgcaattgc tccgatcacg gctccaacaa tcaatgtcca
     9361 taaccaactc ataatataac ctccttcttt gctaatcaat tttagcatat gggatttaaa
     9421 ggggacaaat aattggtttt gctatttcat attttcttct gcaaagtaaa aaaataaaga
     9481 aaacctcctc ttagaagttt tctttatttt ttacttgcgt ttaaacatac tacgaatacc
     9541 acgtttcact acatcaaaga aactcaatga ttgtaccatt ctatcttcat ctacatattc
     9601 tctgatcgca cgaagcactt ttttaggttc tttggaagaa aatgtgtatg taccattttt
     9661 tttcgtttga atggcatatc gaggaatcca ttttcccttt agcatgactg atgctagtac
     9721 ataatccact tcttcccatg gaatttggat atatttgcgt ctatctcgcg catggtaaaa
     9781 ctcaaaacca ttattaccta tcatgatttg cccgtaatct gtcagacccg taaacgaagt
     9841 agcatcaatt accaagtcta cttttgtatt gattgattga accattttct ccctccagat
     9901 atttgtttat gaacagtata ctatataaaa aaagctcggg acaacgcccg agctatattt
     9961 ttatggatta taaaagtccg atgacgtgtc caacaacacc gactacgaat aaaccaagga
    10021 tgataacgat tggagaaacc tttttcttaa gcaaccacat acataacaat gttaatccta
    10081 atgcagctaa accaggaatc aattggtcta agttgtcttg taatgttgtt accttttcag
    10141 gagaaagggc taagccatta ttaacttgtt caaatgcact cttgattcct tcaccacctg
    10201 aaggcaattt atcccattcg atgtaagcac ctttatctaa ttttacagtt gatacaactg
    10261 gtaagaattt gattgatacc catctttgta caagggcagc taatacgaac atccctaaaa
    10321 ttgaagcacc ttttgttacg tcttgtaaca atccgccaga aaggtcatca gtaattttag
    10381 aaccagcttt gtagccaaat tcttgtgtat accacatgaa tgcccaacga ataatgttcc
    10441 aacctaagaa gaagatgatt ggtccaagga tatttcctcc catagctaat gaagcaccta
    10501 gtgcacctag cattggacgt actgtaaacc agaacactgg gtcaccaaca ccagctaaag
    10561 gacccatcat acctacttta accccttgaa tcgctacatc atcaacaggc gcgccattcg
    10621 cacgttcttc ttccagagcc aatgtaaccc ctaaaattgg agaagcaatg tatgggtgtg
    10681 tattaaagaa ttccaagtga cgttttaatg ctgcagaacg ttcttctttt gttttgtata
    10741 attttttgat tgctggaatc atagaaaatg cccagccacc gttttgcata cgttcgtagt
    10801 tccatgaacc ttgaatgaag gtagagcgcc acgcaacagc taaacgatct ttttttgata
    10861 atttgatttt ttcttctgcc attttatttt cctccttcaa gattaatagt cattcaaaat
    10921 gtcgcctaaa gggtcaccag agttgcttcc gcctccatta tttgatgaac cacccatttt
    10981 agaaaggttc aagtaaataa gagctaatgc aacacctaaa gcacctagag caatcaatgt
    11041 taattgagaa attgcagcta caacgaaacc aataacgaag aatggccata cttcttttgt
    11101 agccatcatg ttgattacca aagcgtaacc tacagctacg accattcccc caccgatagc
    11161 cataccatct gttaaccatg ctggcattga ttcaaggaat gattgcacag tttgtgctgg
    11221 gataaatagc aacgctgctg ctgggaccgc gatacgaacc ccttgtaaac atacagcaat
    11281 gatgtgccac atttcaacct tacggatgtt tccttcttca gcagccgcat ccatcaaatg
    11341 aacgattgga acagcgattg tacgtacgat cattgttaag aacaaccctg caacagccaa
    11401 aggaacggca atcgcgatcg cagaaggaac acctttaaca ccttgtccac ctaaaactaa
    11461 aataattgct gatgctactg atgctaatgc agcatctggt gctacagcgg caccgatatt
    11521 tgcccaacct aaagcgatca tctgaagcgt accgccaagt acgataccag cttcgaggtt
    11581 accggtaact aaaccgatca atgtacatgc cactagtggt tgatgaaatt gaaattcatc
    11641 aagaatacct tccataccag ctagaaaggc aactaatacg actaaaatta ttgaaataat
    11701 agacatgata agcctcctat aaattttaat attatttatt acgcttttgc taattcagct
    11761 tttgcttttt tcaaaatatc atccatgtta tcgcgtgaat cattaggtac tttacgtaca
    11821 tcgaatttca cacctttttg ttcaagcttc tcaaacgctt caacgtcttc ttgtcccata
    11881 gacaatactt tacttacaac gactttaccg accgaatgcg ccattgaccc aacatttaat
    11941 tctttgatgt ctacgccacc ttcaacagct gtcaatacgt cttcaggatt ttcaaataaa
    12001 agcaatgctt tggtatttcc aaaacgaggg tcttttgcta cttcgatcat tttgctaata
    12061 ggaataacat ttgcttttac acctggagga gcagcttgtt cgattagtct cttacgcaga
    12121 tcatcctttg atactgcatc tgaaacaacg ataatacggt ttggttgcac tgcttttgtc
    12181 caagctgtcg caacttgtcc atgtaacaga cgtgagtcaa cacgtgctaa tacatatttg
    12241 atttttccgt ctccgaccac agttccttct ggaagtgctc ctttaggttg tgcgtcttca
    12301 actgctgctt tcggtgcttc tgccggttct aattcttccg gttttacttt tacaccgtct
    12361 tttgctgttt caatgatgtg tgctgcaatt tcatgagcag attccattga aaagcgtgat
    12421 gcgtaggctt caatcaacat tggtaaattc aaaccgctga cgattgccca tttatctttg
    12481 tgctcttcga ataatgtgtt tgattgattg aacggtgttc cgccccataa atcaactaag
    12541 aataacactt cgtcttgatt atcaaaagaa gcaaccgctt cttccaattt ggctctcaag
    12601 tcatctggac cttcacttgg tttcaaaatc acggctttga cgttttcttg ttcgccaaag
    12661 atcattgaac cggattgtaa gattccttca gcaaattgtc catgacttgc taggataatc
    12721 cctaccatat ttatacctcc tatttacttt tgttgtaaca aattcaaaaa tattaataat
    12781 tgctaaccat tacaacagaa ttatttgacc ttttccaaca accattcttg ctacaccttt
    12841 ttgattttcg ctagtagttc catcaaaagg attttcctgt cagcaggtac ttttcgaatc
    12901 tctaactcca cttcttgact gttcaagtaa cgaaaggaat caatatcttg ttgatttact
    12961 gaaacaaaat tggtaatcat tgatttgcct tcagtaaaac tcataccgcc gatattcaac
    13021 gacttcaact gtacaccgca gcggacaacc gcttcaacat cttggggatt ggtgaataaa
    13081 agcatcactt ttgctcgtga taataatcca ctatgataga tttgaatcat tttctgcacg
    13141 gttattacat ttgctgtgat ccccggcggt gcagcttctt ttagtagaaa ctttctcaat
    13201 ttatcttgag cgactacatc gctgatcaca atgatacgtt caacacctgt ttgcttcgac
    13261 caaactgttg cgacttgccc gtggattaaa cgatcatcta tacgtgccaa tcgaatatcc
    13321 atctgcaaaa ctccttcttc ctcactactt cacagaaacc cctatcattt ctgtgtgaac
    13381 aaccacctcc tagcacacac tactataagc aaaaagcgtg ccaacttttt tacgatacac
    13441 taattgaatt taaaggattc ttaaccaata cacaaaaacg atacactata aaagtgtatc
    13501 gtttttgtgt attcatggca cagtgtattc ttttttatct aactgattat ggactagacg
    13561 tagcagataa tacatttctt ctatcggcac ttttactttt atctgatctt ccaacagaac
    13621 aactgaggct gccaattggc tataaagagg atcattcgtt gtatttgtca attcgttttc
    13681 ttccacagtc aatggttcat tccgaataat acgttcgatc attcctgctg tgtgcatcac
    13741 taggttgatt ttgaatccat attcttcatc gccgattccc gtcgtctgag agatttgtgt
    13801 agaaaattgc cacattggat cgattaactt actaccatta ataaagatga agttatcaga
    13861 gataaactca acacacgtat ttttagctga ctcttcatct agggagatga attcagtttc
    13921 ctccaattct gattccatca gcaactgatc caaaatgact tcgatatttt gatcaataaa
    13981 acgttctaaa ggaataaatg gggcttggat attcaaatca gtaatcccag tagtagctat
    14041 gatctgatat tctttttgga taactggcag ttcttctttc acttccacaa tcgacaaagc
    14101 tagaacttct aattctgttt cttgacgctt gtttaccgct cgttcgatca attctttgat
    14161 tctttgtgct gtaccttcgc cagatgcgca gatagccaaa acagcttttt tcttatgaat
    14221 aggttttgct tcctgaacag attctacaga agatatttct gcgtaacctc gaaaattttt
    14281 caatgattca tgcaacatat ctagatctgt ccctaatact gagacctttc gtacagtttc
    14341 caaaactaga gaagttgtta ccatatcaac agtacgtact ggaattccag tgtctctttg
    14401 aatttgcgaa ttaaacgacg caagggaccc catatctact aagagtatga ccccgcttcc
    14461 ttcatctact tcttgtacat tgcgttcaat tcggtccaat gctgttttcg gatccatatc
    14521 caaaggcatg tctactgctc gtacgttctc tgcatctaac aactgttgga caacttggac
    14581 catactgctt gctgtgctgt ttccgtgagc tgcaacgact acaccgattc tgccgcttgc
    14641 ttgatttgcc cgtaacgaga cgagtagaac ggtcaagtaa tagtcttcac tttctggaat
    14701 ctccacttga aaatacgttt cgatataact acgcacttct ttcgcaacag catattcatc
    14761 tggaaaatca aaagccatct cacggatgtt atcattcgta tgccgttctt ctcctaagtt
    14821 gatttttttc aaaaaagaac tgatatgcaa gctcatagca taaataaagt tttgctgaaa
    14881 ctcatatggt aaagatcttt tgaccattac ataaatctga ttggtcactt ctatgatttt
    14941 cggatctaca aattctgcta atttgctgtc tgcattaaaa gaaaaaccat ggtctttata
    15001 gaaagacttc agatggatgt tgatatctgt agaaatgaaa tgattgattg cttcttgatc
    15061 caaaccatcc gacttcagta aagctgcttt atctccgatg atatcatata gattataagg
    15121 taactcatag gagtccgatt ggattttcat gatcgtatca tttggtgcta cagttatctt
    15181 tggctccaat attttagaaa gctctgccat tgcactgcgg ttgcttgcta attgaatcaa
    15241 tccgctacga atcccttctg tcaaatcatc gattgtgatc gagatttcgg gtgattgcat
    15301 atgatttaga aatcctcgtg cacatactaa ctggatattt gacttcaatt gtcctatatt
    15361 tccataggtc acactgccga tcaatgcttt tgctacatct tctgtcaaag aaatctttcg
    15421 ctgcgtgcgg tttgcttcgt gggcaatcat gatttttact aaatcgactt tctcatttgc
    15481 aggacgtttt tcaaaagccg gaagtttgat attgattggg atacgccgaa caaaagtttc
    15541 taatagagaa gaacctgggt cttctgtggt cgcacctacg atccgtacat ttgcttcatg
    15601 ggatttcgtt gtttccccaa gacgactgta agttccatga tccataaagt aaaagatcat
    15661 ttcttgacct tcaggcggca accggtgaat ctcatccaaa aacagcatac cgccatccgc
    15721 ttgatcgata atccccattt tttcttcatc tgcgcctgta aaagcacctt ttgcgtaccc
    15781 aaataaatga ctcatcaaaa gctcagggtt attggcataa tcagcacaat tgaaaacaat
    15841 cagttccgtt tcctcatcta ttacatgatg cgcttttgca aaatgataca tcgcgtgtgc
    15901 aaaataagtc tttcctgatc cggtaggtcc tgtaatcaaa caatttaatc ctcttggcgg
    15961 atacaaaatc gcagcttttg cctgttccac tgaatttttc atgctgccgt tagctccaat
    16021 gatttttgca aagatatcct tagtatctat ttggagtgta tttttttctt cagagaccgg
    16081 cgtttctttg taactgacta catgttttgt aactggcttt acgtgcgtaa cgagtgtttg
    16141 atatatgtaa cgtactggtc gtccgtctgt ctttatcagt tttccttcgc gcactagctg
    16201 attcagatct ttactgctat ttgttcgctg aatccctaac acttcagcaa tttcctgtgt
    16261 tgttactcct tgatcatatt ctgcctttgt taaatgagcg gttttttctt tgacatacat
    16321 ataaattcgg tcaatgcgtt ttgccaatgg tatcgctcct tttctataga ctattgtact
    16381 taggcttcaa aacataatac tatgtattta tttctgtttc gtcaactatt tacctgattt
    16441 tgttttgttg ataacacgcg gatagataga aatgttcaat ttaaaagaac gaaaaatccc
    16501 gatacgattt ttataatgga aacaagaaaa agaacactgt ttaccatata attatttcac
    16561 tgatagcaaa caatatagct tccatcaatt gaaaacgata gttatcaaaa catcctgatt
    16621 ccaaattggc aaaaaaatat taagtgtaaa aagacaaagt aaacttcgta gcctccacta
    16681 caacttttat ttttataaac aaaaaaggct gtgacaaaag tcttgtcaca acctctttaa
    16741 tcataagatt caattaagct tcttgagcta ctggataaac agacacttgt tttttgttac
    16801 ggcctttacg ttcgaaacgt actacgccat caacttttgc aaataaagtg tcgtctccac
    16861 cgatacccac gtttacacct ggatagattt ttgtaccgcg ttgacggtaa agaattgatc
    16921 cacctgtaac tgtttgtcca tcagcacgtt tagcacctag acgttttgat tctgagtcac
    16981 ggccgttaga tgtagaaccg ccaccttttt tgtgggcaaa taattgtaga ttcatagata
    17041 acaacatggt ctgcacctcc tatttatcat taattgtttt aatttggata tattctgagt
    17101 tttcagcttc tatcgattgt aatcctaata aaagattttc taatagaatc tcagcaatat
    17161 tgttttgttc ttgtgtcatt cctgaagtga cttcggtata aagataaccg ccttcttctt
    17221 cattcatttc aacaatcggc tcaaaaccgg ctaatgaggc aatcccgttg acagtgctga
    17281 tcgctaacgc agaaacaccc gcacaaacga tatcacttcc ataaggacca gcatcagcat
    17341 gcccggtcaa agtgaatgaa acgatctgac ctgcgtcatt tcgcttaaat gttcctttga
    17401 tcatatatag gccttctttc tcaaacgcta ttaagcgttg atcgcgtcga taaccacttt
    17461 tgtatatggt tgacgatgac cttgtttacg gtgtgaatgt tttttaggtt tgtatttgaa
    17521 agtaacgact ttcttttgtt tgccgtgttt ttcaacagta ccttcaacag ttgcacctgc
    17581 aacagttgga gcgcctactt ttgtagattc tccgcctact aagataactt cgtcaaaaac
    17641 aactttttct cctgcttcaa cgtcaagttt ttcaacatag attgcttgtc ccacttcaac
    17701 ttttacttgt ttaccaccag ttttaataat tgcgtacatg ctataaagca cctccttctg
    17761 atatacttag actcgccatc cgaagtgaca gcatatgctg tgcttattac ttgttctgag
    17821 cggttgtagc tgtggagtcc acaattacaa cagtactagc ttaccagaac agcaaccgtt
    17881 agtcaactaa atttaaaatc aaaaagtaaa acaaaaattc aagcaatact tctgcttttc
    17941 tatcctcaca gttctaccaa ataaaatagt cgcattgtgt ttcttttatt cttataataa
    18001 aagaaaaagg aggagcataa atggaatacc caaaagaact gatacaagaa gcttctttaa
    18061 gaatgaacgg ccgtcctgta gaaggattta tcgctgggca aggacctctt catcctaaac
    18121 tgatgctcgt gggagaagcc ccagggaaaa cagagattga tacgcatgtt ccttttagcg
    18181 gtcaagctgg aaaagaattg atgcaggcac tttcttcaac tggcttaaca cgagaagagg
    18241 tgtatatcac cagtgctgta aggagccgcc cgtatcgcgt gactcatcgg atcaataaac
    18301 ggacacaaca gtcagaaact gtttatccaa atcggacacc tactcgttcc gaagtatttg
    18361 cgcatgcacc aatattggat tacgaactga tgaaggtcca gccaaaatta attgcgacac
    18421 ttggaaacat tggtcttcaa cgtttacttg gcaaagaata tacggttacc aaaaatcatg
    18481 gtcaactcta tacagggcct gtcttacaat taacagaaca aaaggatgcc tacgaatggt
    18541 cagaaaaaaa ctatcgaatt cttccacttt ttcatccagc agctattttc tacaatcgct
    18601 cccttgtacc tgttatccat caagactggc aagtactagc ttcactttta cagcaatatt
    18661 aaaaagaaca gacaagacca taaaatcttc agtttacagt cttgtctgtt ctttttcatt
    18721 gttttaatgg ctaattgcag tatatttcgc atgtaaagct gtcaacgcat gagcaactgt
    18781 ttgatgttga tgcgtgaatg tatgttccca caagtgagaa agttgttttt ctacttctgg
    18841 ctgcaaggaa gtatagataa tcgtttgtcc tctttgctct gctttttctt gaaattcatc
    18901 aaaaactgca cgtgccgtca aatcaatact tggtacgcct cgcatggaga aaatgacacc
    18961 atcgtgatga tttagttctt ccaatttatt tttgagtttt tctgaagaca taaaaaacag
    19021 tggaccacta atatacacta ctgtccagtt attcagcttt tccgtttctg gcagccccat
    19081 tctttgccaa tcgatcgttt ctaatgaaat cgtgatagca gcgcttttga caacaaaaaa
    19141 tacacagccg ccgatcaccc cgatcacgat agcaatactt aaatcaaaga taactgtaca
    19201 aatcatcgta aggataaaca atagaactgc tgaccaatat ttattagtaa atagctcctt
    19261 gatcgtttcc cattcattca tacgccaagc cgtcacaatc aaaacacctg caagtgctgg
    19321 cattggaaac tgtgacatca ctggcgcaaa aacaagcatg gagagcagta agacaactgc
    19381 atgtatcata ccagctaatc tagtttgtgc accagatttg atggccacgc ttgtacgggc
    19441 gatggccgca gtagcaggaa tcccgccaaa gaaaggaagc aacagatttc caattccttg
    19501 cgccattaat tcttgattgc tatctaaggg cttatttgcc attcggccag ccgaagcacc
    19561 acatagcaag ctttcaatca ttcctaataa agcaatgcta atagctggaa ctgccacttg
    19621 ttgcaaggca gaaaagctaa aatctcccat attcaaacga ttactactga tcaatgtttg
    19681 tggaatctta cccacagttg ctactggtaa atggaacaat agcataactg ctgttgccaa
    19741 aatgatagcc agcagcgaac taggcattcg tttcgcccat ttttttggat agataaacat
    19801 ccctaaaatg actagccctc ccatgatcaa agaggctgtg tttatcggaa atcctatcgt
    19861 ttgataacta cttagttttt caataacgtt tgtaccttcc gagtgaacac caaataaatt
    19921 atcgatctga cctaatgcaa taatgatagc aatacctgaa gtaaaccccg taattacggg
    19981 tgctgggata aaagaagtca gtgttcctaa tcggaaaagt cctgctgcaa gtaaaaatag
    20041 acccgctaaa aaagtagcaa gcaatacacc ttgcattccc tttgttgccg caatagacat
    20101 caagatagct gccatcgcac ctgtcggacc tgatatttga taaaaaccgc ctgataaacc
    20161 gccaataacg ataccggcaa tgatagccgt aatcaaacct gcggccgcat cagctccgct
    20221 tgatacccca aaagccaagg ctaaaggcaa tgctacagca gctactgtga tcccagccaa
    20281 aagatctttc tgaaatcttg aaagatcata acctgaaaat tcttttttta gtgaggaaac
    20341 ataatttttg aacacctatc taactccttt ttcatgaaat tttctaaaat accattcatt
    20401 agaatatcat atttcatgag ataaagtaat atttttcaca aagtttcctg ttagataaat
    20461 tcttattttt tctatattta taagaaaata gaaagcaatg ccaacagagc tagcccacct
    20521 tgtttgagta aaatccaacg atcgctagtc aaactgccat ataatgcaac aaaaaaaata
    20581 gatattaata gcatacttgt gatttcttta gatgcggaag aaagataagc tccataaagt
    20641 agtcccactc ctaatagtcc attgtacact ccttggttct taaacaatgt ttgaacagat
    20701 tttctgctta actcttcttt actcatttta aaaaccctac ttgtcgtgtc agaatcagtt
    20761 ctcaccgttt cgatatacat gatataaaaa aattcaattg caactagagt cactaaaatt
    20821 ctagatagta tcgtcatatc ttcttcctct tttctgatga gttttatttt tttgctcctt
    20881 ataattgtac tcgataagga tgttttttta ttttatttgc ctttgaaaac aaacaatatt
    20941 ggcacaaaaa acaaagaaaa accgttagaa acctcagttt ctaacggttt tttagcgtca
    21001 caggagggat tcgaaccccc gaccgtccgc ttagaaggcg gatgctctat ccagctgagc
    21061 tactatgaca agaatcagcg gaacatcaat aattatagat aattaaattg cttctgtcaa
    21121 tacgaaatag ttatttaatt agcaaataat gaattatttt ggcccaacta ctaaatcaat
    21181 cttttaaaac gagacattct ccttcagctg ttctaaggtt atcaattgaa aacaggagct
    21241 acattgactt catgctactc ctgtttattt agatttcctg tatcctttaa ttgacttaca
    21301 aatatagaaa cttttacatc aagttcgaat tgagccctcg attcaatcga ttatctacag
    21361 gctgccataa tcatgtatca caactcgatt gtttctgatt cctttgtcat taagatcaca
    21421 ccatcaccta atggcaagat tgtcgatgtc aaatcgggat gatccatcac aacacgaaga
    21481 aattcattta atttacgatg gatagctcgt ttgccacggg gaatctcttc atctgggagc
    21541 aagatcgttc ctccttggaa gatgtcatct accatcaaaa cgccaccttt tcttaacaaa
    21601 cgtaagcatt caggtaaaaa ttcaatatat tttgattttg cactatccat aaaaataaag
    21661 tcatacggac cagacaactc cggcaagata tctgctgctt gaccttcaag caaagtcact
    21721 ttatctgtca gtcctagacg ttcatagttt tttttagctt tctcgatcat gacatcgaaa
    21781 cgatcaattg tcgtaacatg agcgttttct ccgattgtcg tggccatgac acttgatgaa
    21841 aaaccgatag ctgctccgat ctccaagatt cgttcaggct gaagctgtcc aagtaaaaat
    21901 ttcaaaaata caactgtttc atggggaata actggtactt ctgctacatg agcttcttct
    21961 tccagtttgc ctagctcacc cggtaatttt ttttgctggg tacgcataaa atccaatagt
    22021 tcttctttga ctacaggacg atgcatcatt tcattgcgca tactactcct cctcttcaca
    22081 cattatacga acaactgact aaatctacaa gctgcatgag tgttttctcg tgtttcatgt
    22141 tcagaagagt cgttggatct ctggaataca tttatgtttt taacattctt acaaaaattt
    22201 ctgtgttcgt ctccgcttct ttttcaactc tacaaaggta ttccatgctg tgattcctgt
    22261 taggcaaaaa gcaatcgtaa agaataaccc ctgaatccat gcaaatgccg tttttgaaag
    22321 gactagtcca atatatggaa tctgaaagat gggactaccg ataatatttc tcttttttac
    22381 tactccaggc tcaatataag tctttgtatc agcttttgta taaaaatctt cgtggttgtt
    22441 ttcaacggct attacgcgac gcgtcgagat tttttttcct gaattttcat aatatgtaat
    22501 aatatctccg actaaaatct catttgtatt tttcggtcgt acatatatca gatttccttg
    22561 tgcataatat ggactcattt ctttgtcctc aataatataa ggagtcaaac caaaaattcg
    22621 gggaaccaag acgacgagaa gaataagaat taaaaatata atcaacgtta tagaacttat
    22681 aaaagttatt tttttgtaat caggtatcgt tttcaacttc tttctttatt caatccttct
    22741 taatcatata ataacgataa attttttcaa attatagctg taaaaatgtt tccctttaat
    22801 aattatatgt ttctaattct atttcctcat ctttatctca ttttttatta taaataattg
//
LOCUS       DADVXV010000043        22763 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.044, whole genome shotgun sequence.
ACCESSION   DADVXV010000043 DADVXV010000000
VERSION     DADVXV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.044"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            6..305
                     /locus_tag="KB969_001580"
     CDS             6..305
                     /locus_tag="KB969_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869567.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="KB969_001581"
     CDS             378..1739
                     /locus_tag="KB969_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBB6869568.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="KB969_001582"
     CDS             1761..2021
                     /locus_tag="KB969_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869569.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="KB969_001583"
     CDS             2035..2787
                     /locus_tag="KB969_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBB6869570.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="KB969_001584"
     CDS             complement(2881..3486)
                     /locus_tag="KB969_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6869571.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="KB969_001585"
     CDS             complement(3539..4513)
                     /locus_tag="KB969_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBB6869572.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="KB969_001586"
     CDS             complement(4891..5610)
                     /locus_tag="KB969_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6869573.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="KB969_001587"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="KB969_001587"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6869574.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="KB969_001588"
     CDS             7161..8558
                     /locus_tag="KB969_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6869575.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="KB969_001589"
     CDS             8639..9079
                     /locus_tag="KB969_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBB6869576.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="KB969_001590"
     CDS             9227..9553
                     /locus_tag="KB969_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6869577.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="KB969_001591"
     CDS             9554..10303
                     /locus_tag="KB969_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869578.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="KB969_001592"
     CDS             complement(10383..10838)
                     /locus_tag="KB969_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6869579.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="KB969_001593"
     CDS             complement(11265..11540)
                     /locus_tag="KB969_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869580.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="KB969_001594"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="KB969_001594"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBB6869581.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="KB969_001595"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="KB969_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6869582.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="KB969_001596"
     CDS             14770..17436
                     /locus_tag="KB969_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6869583.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="KB969_001597"
     CDS             17800..18552
                     /locus_tag="KB969_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6869584.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="KB969_001598"
     CDS             complement(18574..19728)
                     /locus_tag="KB969_001598"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBB6869585.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="KB969_001599"
     CDS             19913..22354
                     /locus_tag="KB969_001599"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBB6869586.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22511..>22763)
                     /locus_tag="KB969_001600"
     CDS             complement(22511..>22763)
                     /locus_tag="KB969_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6869587.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         7290 a         3995 c         4750 g         6728 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttggctct tcgtcaaatt
    22441 gtgttggcga agacaaattt gaataaaact tagtccgata tgcggcgcgt tctgtgcgcc
    22501 gcatattttt ttagttttca aagatcagac cttgttgtaa atagatccgt gcccgaaagt
    22561 tataaaagtt gcgataacca aacgcaattc gtttaatcag cttgatcttg ttattcagcc
    22621 cctcagtgac gccgtttgag tggggcacct taaaggcatt tgaaataccc gattggtagc
    22681 gatggaagat cgtgaatttc tttttaaacg actgaggtaa cgtagatgaa attgttttaa
    22741 gggtttcttg aaagccttcc gta
//
LOCUS       DADVXV010000044        22736 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.045, whole genome shotgun sequence.
ACCESSION   DADVXV010000044 DADVXV010000000
VERSION     DADVXV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.045"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            21..542
                     /locus_tag="KB969_001601"
     CDS             21..542
                     /locus_tag="KB969_001601"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6869588.1"
                     /translation="MHIGDKIHKLRRLNNETMNDLVKQTGLSKSWVSDIESGKKQRAD
                     FNKICAIAKHYKVSLEYFQDDYLDSDEHEDIIPLTDETRVKSVKSLEQSLKYLNNKQE
                     PNLLEIKLKDTDSVPEVYYKGQKLEGLIDVSYHYHTTTDVVAGSTNDINMEYLGEVTK
                     YPDIKTIGHKRDV"
     gene            543..860
                     /locus_tag="KB969_001602"
     CDS             543..860
                     /locus_tag="KB969_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6869589.1"
                     /translation="MKEARPRDEIDKLYKTKRWRDLRQVVIARDFGMCQECKRRGRNT
                     RGTIIHHIVEAREDLSLFWSVDNLECICVACHNREHPERSGGKKKPKPKSHIVKMYST
                     PER"
     gene            complement(1017..1181)
                     /locus_tag="KB969_001603"
     CDS             complement(1017..1181)
                     /locus_tag="KB969_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HBB6869590.1"
                     /translation="MGELYKPGEDNKPKGTYKEVGPRGGNVQGGREVKIDPGDRLPPT
                     SQKGNKWTKK"
     gene            1284..1805
                     /locus_tag="KB969_001604"
     CDS             1284..1805
                     /locus_tag="KB969_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBB6869591.1"
                     /translation="MPQPAKSAKLQLLNGNPNKKNTEELRKRAAAEDKLKMATDKIKP
                     PLWLDSLGKDTFEFIADELLSVDLISNPDVHTMALYSNWYSQYVSLEKQLRKLQREYK
                     LNYALAKKEAEARGEPFNEPNELIGNPLSRQMDTASRNLRSFGADLGLSPAARAKLAI
                     KMADDGGDDDDDF"
     gene            1792..2265
                     /locus_tag="KB969_001605"
     CDS             1792..2265
                     /locus_tag="KB969_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBB6869592.1"
                     /translation="MTTSNILDMSYTERVDYWQSYLEEQASWGGFLKCPYPELLTTWY
                     AERLIDGSIPASKENIQAAKRHMRDLQRQGTDDFPWIFDEEKGHRPIRYIEKKCKPTE
                     GDFGSFVLQPWQHFIIGSMYGWVHRDTGERRFREALIFVGRKNGKFCRLKIGQNR"
     gene            complement(2272..2430)
                     /locus_tag="KB969_001606"
     CDS             complement(2272..2430)
                     /locus_tag="KB969_001606"
                     /inference="COORDINATES: protein motif:HMM:NF024064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HBB6869593.1"
                     /translation="MDKYGLKNRIRISNAIDKDLYEGLKKMSEETMVPMSKLLDKAIE
                     LLLKESQK"
     gene            2523..3284
                     /locus_tag="KB969_001607"
     CDS             2523..3284
                     /locus_tag="KB969_001607"
                     /inference="COORDINATES: protein motif:HMM:TIGR01453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6869594.1"
                     /translation="MKKYIIYKHLNKINGKIYIGVTNDIGRRWRSGGIEYKPPKNETQ
                     HHRSFWNAIQKYGWENYDHLIIEEDLTMKEAFEKEKFYIELYDSTNKKKGYNIAKGGN
                     GGIIYKVHPKGMLGKKQSKEFSSNHSKWAKNHKNNCMTNGDVVWGVTHEHPKGMLGKH
                     HSKESIMKKKAYSGENAVTSKPIVAIERDGTKREFHSAKLCMAYYSISTCVFYRLLKD
                     GAPYVINPKANYRNKEKILAIEGIMFKHKEDTEVS"
     gene            3504..4823
                     /locus_tag="KB969_001608"
     CDS             3504..4823
                     /locus_tag="KB969_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003666013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6869595.1"
                     /translation="MVAYDDEQGANVYVLANARDQASLLFDKAAEMVKQSPALFKKFG
                     KPKRSSINYAPAFSKMEPRASDSRKLDGLNTHFGIFDEIHEFTNYNLINVIKKSRGTR
                     KQPLIVYITTAGYVLDGPLMSYFEQGVDCLEHLEDDIDERTFYYLAKLDSAEEADDPR
                     LWIKANPNICLMNFVGMLDDYVKDKKDPKEYADWITKQFNLFSDIDELSFVDMPTIKR
                     NNKTIDIETLKGKKCVGGFDLSETEDFTAAVLEFPLETGEVFILQHTWIPQARFDRDN
                     NQERIKAWEKVGDLTIIPGDYVNYEYVLNWFVENSKIYDIVKINYDKAKALRLNKELE
                     NAGFETNEIRQGFLSLGGPMQNFKEMLLDGKVIFNNSKLYRWYLSNVKLVMDRNSNWM
                     PSKQSKSRKIDGFAASLNSHAEVLNMLVNPVGTGKVTYYSISDLMNM"
     gene            4839..6059
                     /locus_tag="KB969_001609"
     CDS             4839..6059
                     /locus_tag="KB969_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6869596.1"
                     /translation="MSILDRLRSFGRAKPKASKQEYFLNDPGLIPYLVGKDEISEGIF
                     SVISRVSNVFASLPLKMIDAEFGQPDDCPAYNLLSEGPRYFTKFDFFRDVEVLRNYQG
                     NAYVQIFRNINGEVADMALIKPGACHPVIDMDSGELYYQVTATDKGSYKQVIYVHYME
                     MLHFKQPRFGGLEGTDPTKVLTNTLGYDREVRKISLSQLKGGNEGLKVKFASNVDEEA
                     KKATVKNIADFYRQNGGLLVEENGVEIERLQRELVDSKLLDTDKVSRSRIAMVYNVPE
                     HFIGSNQSSYSSQEQLNMEFLTYNLVPTVNQYEAELNKKTLSRTEKAKGYRYKFNVAS
                     LLRADTQARGQFYQIMRRGGAYSANDVRRFEDLQPINKTGMDDYHISGDLYPIDMDPT
                     LRKTNSSKSVAENG"
     gene            6094..6771
                     /locus_tag="KB969_001610"
     CDS             6094..6771
                     /locus_tag="KB969_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBB6869597.1"
                     /translation="MKKVTLSGDVVDNDTAWLYDWFGIDCISPGKISAALTEAAGDEV
                     ELDISSNGGDVLAASEIYTAIRAYPGKVSGNVVSIAASAASVIACACEPLRISPTAHI
                     MIHNAWVTTSGNAEELKANAEMLSSVDESIVNAYEIKTGLDRKKLADLMAKDTWLNAQ
                     TAVAEGFADEIMFAEAPVTVLNASQPVIPKNAVTKLKNLILKAETPQEETLLQKKLKA
                     LNGGKNE"
     gene            6768..7964
                     /locus_tag="KB969_001611"
     CDS             6768..7964
                     /locus_tag="KB969_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6869598.1"
                     /translation="MNLEQLKNAWVEAGSKVSDLNAQLNAALVDDEKTEEDVVSLQAQ
                     VKAARAKRDGLKEQVANMEAEQVLNVKKEPLDKKDENLKNKFIKDFKAMVNGDPAIMA
                     TLTSNTDESGNAIGLTIPVDVQTTIHTLVRQFDSLQEYVNVEKVTTTSGSRVYEKWSD
                     INPLTALDTEDGEIPANDDPALYLIKYLIKRYAGISTVTNSLLKDTAENILAWLSNWI
                     AKKVVVTRNTKILAAIDGIKAAQKKDVTDVDGIKDIINVQLDPAIEATSMFITNQDGF
                     NVLDKVKRADGSYLLQKDVASATGYTFLGKPIKKIASRFLPNKGTQATPKYPLYIGDL
                     KEAVTLYDRENMSLLTTNIGGGAFETDTTKVRVIDRFDVQLVDDEAVVLATFTSIANE
                     VPVTNG"
     gene            7979..8302
                     /locus_tag="KB969_001612"
     CDS             7979..8302
                     /locus_tag="KB969_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6869599.1"
                     /translation="MILDPKMDLDEIKNALKIDTDDDDVEVRRAVQAAIAYIRGAIGN
                     DKPSFYKQENDTVDLINLAILQLADHYYNARSATVSGNLREYDLGFTSLILQLKARYL
                     LFVEE"
     gene            8306..8641
                     /locus_tag="KB969_001613"
     CDS             8306..8641
                     /locus_tag="KB969_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6869600.1"
                     /translation="MPLIQTGNLNQRIKFVRDTTVKDEDGQVVRTSTTILTCWASVQT
                     QRLNDIKTSIGTALEGTLTFIIRYQQKSELTNDMKVRWNGKTFEIITITKGEFAKDFT
                     TIIAKEVSK"
     gene            8638..9033
                     /locus_tag="KB969_001614"
     CDS             8638..9033
                     /locus_tag="KB969_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869601.1"
                     /translation="MSVEVDATEVYKALREVKANVQRVESPALRKAGEYAQEKLQQNT
                     PYWDGTKSNGKRGSYMQEHAKDHVVTSSVKNGLIEVGYDKDVSWRMHFIEFGTIKQRP
                     KGFVQKTQKQIEKQVTQIIADEVKRRLGL"
     gene            9030..9401
                     /locus_tag="KB969_001615"
     CDS             9030..9401
                     /locus_tag="KB969_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869602.1"
                     /translation="MKTAVSQVYSILNSNEKTKNIDFYTNSVPESAQTVPSLPVGRIT
                     EIFGNYEDFASNNPLTIQFNVQVDVWVSTLKEVDAFYFALDEIMRGNGWQCAYTEQTD
                     DEDLEGAKRIIKRYVANISLN"
     gene            9417..9977
                     /locus_tag="KB969_001616"
     CDS             9417..9977
                     /locus_tag="KB969_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6869603.1"
                     /translation="MATVGFESVIFGVKTGAGGTLKELVADKSKGGAIEAKITGLGAT
                     SNTTYASNVPFFIASKGVSSPKVTLDVADLMDNGIYSEIIGAKTVDGVNVIGSETEAP
                     YVSVVMVTANKEGKRLFMGLAKGKFSHPDIDMKTAEDKGVELQTDSIEGEFISDERGY
                     VYLTAVESEEMTLQKFKDLVNNKAGE"
     gene            10104..10415
                     /locus_tag="KB969_001617"
     CDS             10104..10415
                     /locus_tag="KB969_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869604.1"
                     /translation="MIELQLKLDGKKKTFKQQDISARAMRECIKFYEKAEKADLTDLE
                     AIDSMIAITADIFQDPAVTFDAILDGLTASELVPALESVFEQINELGNNEKKQTASKK
                     R"
     gene            10439..10630
                     /locus_tag="KB969_001618"
     CDS             10439..10630
                     /locus_tag="KB969_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869605.1"
                     /translation="MDQIYKDLIESGWTMRDVDEADYHYLLHLFGEVESGEEYVDGAD
                     FIKQFLSAEDLVKLEEGGK"
     gene            10630..14475
                     /locus_tag="KB969_001619"
     CDS             10630..14475
                     /locus_tag="KB969_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBB6869606.1"
                     /translation="MAGKGQPAGNIKLGISLDSTNFGNTLDEINAKVKQAESNMRANL
                     KAYDSAGRSYEALSQKTKDLSTVMEGQNAKVRELTKRRDEAISKYGEESKQVANLNTQ
                     INNATAKYNAYSRQLNDTKKELVYSKTAVNDLSNEIKENERQMNAEVKALKAAGDESG
                     AFEAKQKGLAKQTELSEKAIEEQRKVVKLMADEFGDSANETEDAKRALEKLERQSQIS
                     SRQLEALKSSSDQSGKKIEDFGDKSTRSARKLDGLKDKLGSLKSAFSFGAVAGLAHNA
                     ISSVVSGVQGLVGEAVNASDSLMKFSKTMEFANFGKSQIESSKKEMKDYADKTVYGLE
                     EILNTTAQLASNGIPNYTELTKAAGNLNAVAGGSSDTFKSVAMMLTQTAGAGKLTTEN
                     WNQLADAIPGASGLLQDAMLKNGAYTGNFRDAMAQGQITSDEFNQAIVQLGMNDGAVK
                     AATSTDTLSGSWEQMKSTVINGLQSIIDKVGVENITGFINRVTKGIENSIPKITQFIG
                     WLRDIGTWIVENREPLTWIVGIIGGITLAVKALNVASMLLAITGGTLAAPFVAIGVAL
                     GALAGALVIAYTKSETFRNIVNAAFTAVKNVVMSVINNLVEYYKMLWSVLQWLWEKIK
                     EWASWIGNKFIEMKNSVVNTVQNLWNGVKNFFSNGVGDTWNKVVGWVKNIFNKATELK
                     NKVSDAIGNLWNGIKDTFRRGIDTVFNWFSELPTKMKNAIIGGKNAIVDAFKSIFNAA
                     LKAIGKPVNAIIHGASWVLEKLGADKLEEWKVPQYAKGTPNGGHPGGPMMVNDGRGAE
                     AVITPNGQAFIPRGRNVVLNAPKGTHVLTAEETAYMTGNKAPRYRYAKGTGFFGNLWN
                     NVKGFAGDVGNKLKDVVGDVWDFVTDPGALARKVLNGLGVLEGLVKYPLDVGKGILSK
                     ATEALTNKITELFSSGSLDTSMGMQGVYKYLADVAVAVMKKFPGFVATSGYRPGDPYS
                     HGKRNAIDIALPGVTGGSPRYTEAANYAFEKFANKIGYVITNGKVRDRSGQSGTGIHN
                     DWRPWPDGDHYDHVHLNGVKDPQNTQISGDSVGGSGVERWRNVAIRALKMTGQYSTAN
                     LNALLNQMRTESNGNPNAVNNWDINAKNGTPSKGLLQVIDPTFRQYAMPGFNSNIFDP
                     LSNILASIRYALSRYGSLTNAYRGVGYANGGIVNQHQIAEIAEGNKPEIIIPLDKAKR
                     SRAMQLLSIAMDKLGVSPKTYGNATTVSSDYEILEAIEKQAATTNQLLSLLLAFFKGN
                     SRTDRDLALDIQKILVRRM"
     gene            14476..15348
                     /locus_tag="KB969_001620"
     CDS             14476..15348
                     /locus_tag="KB969_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate protein"
                     /protein_id="HBB6869607.1"
                     /translation="MRTVLLRNRINEEIDLSTEDYFATGLSNMGFEVKKEHVGQWGNF
                     RESSENVEISEFQSSVIISVHGFREKELYNSLVQFLSEGPFELEFAFDGETMVRRCSL
                     KSLSKTEIDPKTSLLTDTLELYFTSNWYSVKREKLIQRPNVVKTRGKVFPYKRSYIYT
                     QNLWEKKGVFKFNNNSVYLTNSKERMSPLKIRVIGKCSNPYWEVIQNSQIIATDGYFI
                     DMTETQTLEVSSLFEDTTAILKDIAGVESSVYQQQDYTKTNFVQAPTGEFSIVFHVGG
                     ADVEIELYEERDLF"
     gene            15345..16394
                     /locus_tag="KB969_001621"
     CDS             15345..16394
                     /locus_tag="KB969_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869608.1"
                     /translation="MILAVTLFHRDLMLYNEHLFSNSFEFGADEINEEASSFTMDKYV
                     PVKTGDFLLAKYIPSGKFAYFGVITSQEDEKISCKSLLSLADSEIPTARVSGDNYEEH
                     IRRLIEYYLLNDPTKQLKDILDVKAESATSHSYQATDTNKHKLSAYILNGFKKYNVKW
                     YFKGIQNRKIYTGIRAVNESIYIKDNSSEFSDWDVFVQAPGAGNENKLLIVDKAMKDI
                     EKPIILSTWYLDEENNLTQDGSKENITKPTVNLVNIYDQTAEDKASYEDVAKSELKGN
                     TYSHEIKVNVVRNAKNLNVETIETGMFATISYKGKIYKSVLTAWRISSDKEFVELTFG
                     NIRSRFMDYFEDNGG"
     gene            16398..17222
                     /locus_tag="KB969_001622"
     CDS             16398..17222
                     /locus_tag="KB969_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869609.1"
                     /translation="MVSNVDGYQFENVKVSAENDARLYHVLYNRKNQVIDGYDQSMNL
                     SSSGLTVKVAAGAAIIQGRMVVVRQEESITVPANSSGYIALTVDLTQEVIPGSILPES
                     EEYEWTNNQVKLEFITKVIKGNLNNGDKVYNLPLCSVTSTGSTVSISKISDSYELTLS
                     KGEILWSGTALMHDTQTVQPSKKMWQTVSGFLLVWLPYENGQAIGDRYVTTPFYKERV
                     TFTNVLGEIVSGFDDYHKKWFSKRINYNSNTNIFTGAASNASGDNANMVLRYIVSF"
     gene            17240..19372
                     /locus_tag="KB969_001623"
     CDS             17240..19372
                     /locus_tag="KB969_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2479 domain-containing protein"
                     /protein_id="HBB6869610.1"
                     /translation="MANLEIKLSANKRQPYLRHRVVGRVGDGGLTTINVQLLEEDEIT
                     PFVINLNGTLKFVGEVSNGNYTEGEPEIIDSTNGLISYTFTKSNFSTSHQFKQAYFEY
                     VDPNGKKVTFQNFIIDVLERVDINSEQAKYYISSLEKLQSEMQTTFNQFISDKQVQYD
                     QIYSKYNELVRLINESDKQVNDRIDKTNDRIDQTNQQIGDLGKLKKMYSNSIDFGDYD
                     YSGNPNLSAKLNASSFSLGTGATVADDNDEIVFTLDGTNQLSKYASKAQVPVAEGKQY
                     TISCEIMLEDGFTGDPSGIRLQHAYLPGGVVVLQTETVPKNELNTWQTLIGTRTVKYT
                     SDVPNEWYPLFRDIRTLKPTGKVRLRKIKIEEGSTATPYQPNLLDDPYWLGKAPLGEN
                     IANKSVTFPIKSSAYSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRY
                     GNLEPVEGLVDTWGLTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGNTRTP
                     NISEYKYRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEI
                     NSQLTASINEVDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSA
                     KLYREGKTVSIYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQL
                     SIGADGAIKWRRNSSYGSDYTFAITYTI"
     gene            19389..19538
                     /locus_tag="KB969_001624"
     CDS             19389..19538
                     /locus_tag="KB969_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869611.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPILNWKPKFNY
                     WEGNK"
     gene            19535..19981
                     /locus_tag="KB969_001625"
     CDS             19535..19981
                     /locus_tag="KB969_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869612.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            19983..20120
                     /locus_tag="KB969_001626"
     CDS             19983..20120
                     /locus_tag="KB969_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6869613.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEADKIISKEESA
                     S"
     gene            20157..20450
                     /locus_tag="KB969_001627"
     CDS             20157..20450
                     /locus_tag="KB969_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869614.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERSR"
     gene            20473..20670
                     /locus_tag="KB969_001628"
     CDS             20473..20670
                     /locus_tag="KB969_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6869615.1"
                     /translation="MILPDKYYQVIKWTVLTVLPALSVLVATLGKAYGWNGTDMAVLT
                     INAAATFLGVITGVSAYNLKK"
     gene            20681..21700
                     /locus_tag="KB969_001629"
     CDS             20681..21700
                     /locus_tag="KB969_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBB6869616.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGVNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            21957..22604
                     /locus_tag="KB969_001630"
     CDS             21957..22604
                     /locus_tag="KB969_001630"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6869617.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
BASE COUNT         7943 a         3841 c         5019 g         5933 t
ORIGIN      
        1 tggattaagg aggaagagta atgcatatag gagataagat acataaattg agacggctta
       61 ataacgaaac aatgaacgac ttagttaaac aaaccggact gtcaaaatca tgggtatctg
      121 atattgagtc tggaaaaaag caacgcgctg actttaataa gatatgtgca atagccaaac
      181 attataaagt tagcttagaa tactttcagg atgattattt ggatagtgat gaacacgagg
      241 atattattcc tttgacagac gaaacaagag ttaaatcagt gaaatcgctt gaacaaagcc
      301 taaagtatct gaataacaaa caagaaccta accttctaga gatcaaacta aaagatactg
      361 actcagtacc agaggtttat tacaaaggtc agaagttaga gggattgata gatgtaagct
      421 atcactacca tacaacaact gatgtggtag ctggttcaac aaacgacatc aatatggagt
      481 acctaggtga agtaactaag tatccagata taaaaacaat cggacacaag agagatgtgt
      541 aaatgaaaga agctagacct agagacgaga tagacaaact atacaagacc aaacgatggc
      601 gagacctaag gcaagtagta atagctaggg acttcggcat gtgccaagag tgcaagcgtc
      661 gagggcggaa cacaaggggc acgatcatcc atcacatagt cgaggcgagg gaagacctgt
      721 cactgttctg gtccgtagat aaccttgaat gtatctgtgt agcttgtcac aacagagagc
      781 atccagagag atcaggcggg aagaagaaac caaaacctaa atcacatatc gttaaaatgt
      841 attcaactcc tgaaagataa gtttgcagcg aaatgaaggt agccccccta ctctaaaaga
      901 ttaaagagta aggcttgaga agaacggtgc tgtccttcct tcgtaaaaag accgcttttc
      961 aagttttttg gagaaaaagg aaaaagccga ccaatttaag ccggctttgg acgaagctat
     1021 ttcttagtcc atttgtttcc tttttgagaa gtaggaggta atcggtcgcc tggatcaatt
     1081 tttacttctc gtccgccttg gacatttcca ccacgaggtc ccacttcttt ataggttcct
     1141 tttggtttat tgtcttcgcc gggtttatag agttctccca taggaatccc tccctaaaaa
     1201 aatttcggca cagcactgcc gataacttaa ttataaggat tgtgataacg atttcaatat
     1261 atcttttgaa agaaggtgat attatgccgc aaccagcgaa gagtgcaaaa ttacaattat
     1321 taaacggaaa cccaaataag aagaataccg aagaactccg caagcgagcg gccgcagaag
     1381 acaaattaaa aatggctact gacaaaatca aaccgccgtt atggctagat tcgctaggaa
     1441 aggatacctt tgagtttatc gctgatgaat tgctgtctgt ggatttaatc agtaatccgg
     1501 acgtccatac aatggctctc tactccaatt ggtattcgca atacgtttct ttagaaaaac
     1561 agcttcgaaa actacaacga gagtacaagt tgaactatgc gcttgcgaaa aaggaggcag
     1621 aggcgagagg tgagccgttt aatgaaccta atgaattaat tggtaatccg ctctctcggc
     1681 agatggatac agcgtcgcgg aatctccgtt cttttggcgc tgatttagga ctatcaccag
     1741 cagccagagc taagttagct attaagatgg ctgatgatgg tggtgatgac gatgacgact
     1801 tctaatattt tggatatgtc ctacacagaa cgtgtggact attggcaaag ctatcttgag
     1861 gagcaagctt cttggggtgg ctttttaaaa tgtccatatc cggaattgtt aactacttgg
     1921 tatgcggaac gattaatcga tggaagcata ccagccagca aagaaaatat tcaagctgct
     1981 aaacggcata tgcgtgattt gcagcgccaa ggaacagatg attttccttg gatctttgac
     2041 gaagaaaaag gtcaccggcc tattagatat atcgaaaaaa aatgtaaacc aactgaaggc
     2101 gactttggtt cgtttgtttt gcaaccttgg cagcatttca taattggatc catgtacgga
     2161 tgggtacatc gtgatacagg agagcgtcgc ttccgcgagg ctcttatttt tgttggacgt
     2221 aaaaacggta agttttgccg tttaaaaatc gggcaaaatc ggtgaaaacc tttatttttg
     2281 gctttctttt agtaataatt cgatagcttt atcaagcaat ttagacatag gaaccatagt
     2341 ttcttccgac atttttttta atccttcgta taaatcttta tcaattgcgt tagaaattct
     2401 aattctgttt tttagtccgt atttgtccat gtgtgacact cctttttatt ttactataac
     2461 atccgattcc accgcttgca actaccatca attgatggta gtatataaaa gaggtgagta
     2521 gattgaaaaa atacattatt tacaaacact taaataaaat aaatggcaaa atttatatcg
     2581 gtgtcacaaa tgatattggc agaaggtgga ggagcggtgg gattgaatat aaaccaccaa
     2641 agaacgaaac ccaacaccac agaagttttt ggaatgcaat acaaaaatac gggtgggaaa
     2701 attatgatca tttgattatt gaagaagact taacgatgaa agaagctttt gagaaagaaa
     2761 agttttatat tgaactttat gactcaacta ataagaaaaa aggttataac atcgcaaaag
     2821 gcggaaatgg cggaataata tataaagttc accccaaagg aatgctaggg aaaaaacaat
     2881 ctaaagaatt ttcttcaaat cacagtaaat gggcaaagaa ccataagaat aattgtatga
     2941 caaacggtga tgttgtatgg ggtgttactc acgaacaccc aaaaggcatg ttgggaaagc
     3001 accacagcaa agaatcaatt atgaaaaaga aagcatatag tggtgaaaat gctgtaacct
     3061 caaaaccaat tgtcgcaatt gaacgggatg gaactaaaag agaatttcac agcgctaagc
     3121 tttgcatggc ttactattcg attagtacat gtgtttttta ccgactttta aaagatggcg
     3181 ccccttatgt gataaatcct aaagcgaact acagaaataa agaaaaaata ttagctatcg
     3241 aaggaattat gttcaaacat aaagaagata ccgaggtaag ttagtagatt gcgaaaggtt
     3301 actaactacc gtaacgcgta ggagttgaat aaatataatg ctcccaagag tgtccgacag
     3361 cagataattt gctgaaaatg tacgctaaac tgggccagaa ctgactgacc gatgaaaatg
     3421 agggtgacct ccagagtgcg agataaaaag ctcgcagata ataacaatcg aaaacatcac
     3481 taatttcagg cctttccaca tacatggtcg cttatgatga tgaacaaggc gccaacgttt
     3541 acgtattggc aaatgctcgt gatcaagcaa gcttgttgtt tgataaggcc gcagaaatgg
     3601 tcaaacaatc gccggcgctc tttaagaaat ttggtaagcc taaacgatca agtattaatt
     3661 atgctcccgc cttttctaaa atggaaccac gcgcctcaga tagccggaaa ttggatgggc
     3721 taaacactca ctttggtatt tttgacgaga tccacgagtt tacgaattac aatctgatca
     3781 acgttatcaa gaaatcaaga ggaaccagaa aacagcctct gatagtttat atcacaactg
     3841 ctggatatgt attagatggt ccgttgatgt cttattttga gcaaggtgtg gactgtttgg
     3901 aacatttgga agatgacatc gatgaacgga ctttctatta tctggcaaaa cttgacagtg
     3961 cggaagaggc tgatgaccca agattatgga tcaaagccaa tccgaatatt tgtctaatga
     4021 attttgttgg catgctagat gactatgtta aggataaaaa agatccaaaa gaatatgctg
     4081 actggattac caagcaattt aacttgtttt ccgatatcga tgagctgtca tttgtcgata
     4141 tgcctaccat taaacgaaac aataaaacca tcgatattga aacgctcaaa ggtaagaagt
     4201 gtgtcggtgg ttttgacttg tccgaaacgg aagactttac cgcagccgtt ttagaatttc
     4261 cgcttgaaac aggcgaggta ttcattttgc aacacacatg gatcccacaa gctagatttg
     4321 atcgagataa caatcaagag cgtatcaaag cgtgggagaa ggtgggagat ctaacgatta
     4381 ttcctggtga ttacgtcaat tatgaatacg tcttaaattg gtttgtagaa aattcgaaaa
     4441 tctatgacat tgtaaaaatc aattatgaca aggccaaggc gctacgatta aataaagaac
     4501 tagaaaatgc aggatttgaa accaacgaga ttcggcaagg gtttctatca ttaggtgggc
     4561 caatgcaaaa cttcaaggaa atgctattgg acggtaaggt gattttcaac aattccaagc
     4621 tttaccgatg gtatctatcc aacgtcaagc tggtgatgga tcgcaactca aactggatgc
     4681 cgtctaagca gtccaagagt agaaaaatag atggttttgc agcaagtttg aacagccacg
     4741 ccgaagtgtt gaatatgttg gttaatcctg tcggaaccgg gaaagtaacc tattactcga
     4801 tttccgattt aatgaatatg taagaaaggt gtggaggaat gagtatttta gatcgtttgc
     4861 gttcttttgg ccgagcgaag ccgaaagcga gcaaacaaga gtattttttg aatgacccgg
     4921 gattgatacc gtatttagtc ggaaaagatg aaatatcaga agggattttt tccgtaatta
     4981 gccgtgtatc gaacgttttt gcgtctctcc ctctcaaaat gatagatgcg gagtttggcc
     5041 aaccggacga ctgtcctgca tacaacttgt tgagcgaagg ccctcgatat tttacaaagt
     5101 ttgatttttt ccgggacgtg gaagttttga gaaactacca agggaatgcg tatgtgcaga
     5161 ttttccgaaa tatcaatgga gaagtagcag atatggcgtt aataaaacct ggtgcttgcc
     5221 atccagtgat tgatatggat agcggggagc tttactacca agtaactgcg actgacaaag
     5281 gcagttataa gcaagttatt tatgtacatt acatggaaat gctccacttt aaacaaccga
     5341 ggtttggtgg cttggaaggt acagacccca caaaagtatt aacgaatacc ctcggatatg
     5401 atcgagaagt ccgaaaaatc tctttaagtc agcttaaagg aggtaatgaa gggctaaaag
     5461 ttaagtttgc tagcaatgtg gatgaagaag ctaaaaaagc tacagttaaa aacattgctg
     5521 atttttatcg acaaaacggt ggactacttg tggaagaaaa cggtgtagaa atcgaacgtt
     5581 tacaacgaga gctggtagac agcaagcttt tagatactga taaagtatct cgctccagaa
     5641 tcgcgatggt ctacaacgtg ccggaacatt tcattgggag taaccagtcg agttactctt
     5701 cacaggaaca gctcaatatg gagtttttga catacaatct agtaccgacc gttaatcaat
     5761 atgaagcgga actaaataag aaaacactat cgagaaccga aaaagcaaaa ggttatcgat
     5821 ataagtttaa tgtcgcaagt ttgctaagag ctgacactca ggcaaggggg caattctatc
     5881 aaatcatgcg acgaggcgga gcatactcag cgaatgatgt ccgaagattt gaggacttgc
     5941 aaccgataaa taaaaccggt atggatgatt atcatatttc cggagaccta tatccaatcg
     6001 atatggatcc aacattaaga aaaacaaact cgtctaaaag cgtagccgaa aacggttagg
     6061 cttttttagt ttgcaccgaa gggaggtgaa aggatgaaaa aagtgacgtt aagcggcgat
     6121 gtcgtggata acgataccgc gtggttatat gactggtttg ggattgattg tatctcacca
     6181 gggaaaattt ctgccgctct tacagaagca gcgggggatg aagtagaact tgatatctca
     6241 tctaacggtg gggatgtcct agcggcaagc gaaatatata ccgctatccg tgcctatccg
     6301 ggaaaggtat ccggaaatgt tgtgagtatt gcagcaagcg ctgcaagtgt aatcgcttgt
     6361 gcttgcgaac cgcttagaat ctcgccaaca gcacacatca tgattcacaa cgcatgggtg
     6421 accactagcg gcaacgccga ggaattaaaa gccaatgcgg aaatgttaag cagtgtggat
     6481 gagtctatcg ttaatgctta cgagatcaag acaggactcg accggaaaaa gcttgctgat
     6541 ttaatggcaa aagatacttg gttaaacgca caaacagcag tggcggaagg ttttgcggat
     6601 gaaattatgt ttgcagaagc accagtaacg gtactcaatg cctctcaacc ggttattcca
     6661 aaaaacgcgg taactaagtt gaaaaatcta atactcaaag cggaaacacc gcaagaagaa
     6721 acgctcttgc agaaaaaact aaaagcctta aatggaggga aaaacgaatg aatttagaac
     6781 aattaaaaaa tgcgtgggtc gaggcgggaa gtaaagtctc tgatttaaac gcgcaactca
     6841 atgcagcatt ggttgacgat gaaaaaacag aagaagatgt agtaagtttg caagcacaag
     6901 taaaagcagc acgggctaaa cgggacggat tgaaagagca agtggcaaat atggaagccg
     6961 aacaagtctt aaacgtcaaa aaagaaccat tagataaaaa agatgaaaac ttgaaaaaca
     7021 agtttatcaa agactttaaa gcgatggtca atggtgatcc tgctattatg gctactttga
     7081 catctaatac ggatgaatct ggtaatgcta tcggattgac tattcctgta gatgtgcaaa
     7141 cgactattca tactttggtt cgtcagtttg actctttgca agaatacgta aacgttgaaa
     7201 aagtgaccac tactagcggt tctcgggttt atgaaaaatg gtctgatatt aacccactga
     7261 ccgctttgga tactgaagac ggtgaaatcc cagcaaatga tgatcctgca ctttacttga
     7321 tcaaatactt gatcaaacgc tacgcaggta tttctacagt aactaacagc ttgctaaaag
     7381 atactgccga aaacattttg gcatggttgt ctaactggat cgcgaaaaaa gtagttgtta
     7441 ctcgcaatac aaaaatcttg gcagctattg atggaatcaa agcagcgcaa aagaaagatg
     7501 ttacagatgt tgatgggatt aaagatatca taaacgtcca acttgatcca gctatcgaag
     7561 ctacatctat gtttattaca aaccaagatg gcttcaatgt tttagataaa gtgaaacgtg
     7621 ctgatggatc ttacttgtta caaaaagacg tagcttctgc aactggatat accttcttag
     7681 gtaaaccaat caagaaaatt gcttctcgtt tcttgccaaa caaaggtacg caagctactc
     7741 ctaaatatcc actgtatatt ggtgatctga aagaagctgt tacattgtat gatcgcgaaa
     7801 acatgagctt gctgacaacg aatattggcg ggggggcttt tgaaacagac accaccaaag
     7861 tacgggttat cgatcgattt gatgtgcagt tagtcgatga tgaagcagtt gttttagcta
     7921 catttacatc tatcgcaaac gaagtgccag taacaaacgg ttaaggagct gatttcttat
     7981 gattcttgat cctaaaatgg atttagacga aatcaaaaac gcactaaaga ttgataccga
     8041 tgatgacgat gtggaagtaa gacgtgcggt gcaagctgca attgcataca ttagaggggc
     8101 tatcgggaat gataagccct ctttttataa gcaagaaaat gacacggttg atctgattaa
     8161 tttagctatt ctgcaattag cagatcatta ttacaacgct cgatcagcaa ccgtgagtgg
     8221 gaacttgcga gagtacgatt taggttttac aagcctaatc ttgcaactca aagcaagata
     8281 tttgcttttt gtggaggagt agcgtatgcc ccttattcaa acaggaaatt taaatcaacg
     8341 catcaagttt gtccgagata cgacggtcaa ggacgaggac gggcaagttg tccggacttc
     8401 tacaaccatt cttacttgct gggcaagtgt gcagacacaa cgcctgaacg atattaagac
     8461 gtccattggt acggctttgg aaggaacact gacgttcatt atccgctatc aacaaaaatc
     8521 agagctaacc aatgatatga aagtgcgttg gaatggaaaa acgtttgaaa tcattacgat
     8581 tacgaaaggc gagtttgcga aggacttcac gacaatcatt gcaaaagagg tttcaaaatg
     8641 agtgtagaag tcgatgcaac cgaagtgtac aaagcgctta gggaagtaaa agcaaacgtt
     8701 caacgagtgg aaagcccagc acttagaaaa gctggggagt acgctcaaga aaagttacaa
     8761 caaaacacac cttactggga tggaacgaag tcaaacggta aacgtggttc gtatatgcaa
     8821 gaacatgcta aggaccatgt ggttacaagc tcggtaaaaa acggattgat agaagtcggc
     8881 tatgataaag atgtttcttg gcggatgcac tttatcgagt tcggaacaat caaacaacgt
     8941 ccaaaaggtt tcgtacaaaa aacacaaaag caaatcgaaa aacaagtaac acaaatcatt
     9001 gctgacgaag taaaaaggag gctaggactt tgaaaacggc agtatcacaa gtctattcaa
     9061 ttctgaatag caatgaaaaa acaaagaaca ttgattttta caccaatagt gttccggaat
     9121 cggctcaaac agtacctagc cttccagttg gcagaattac agagatattc ggcaactatg
     9181 aagatttcgc aagcaacaat cctttgacca ttcaatttaa cgtacaggta gatgtatggg
     9241 tatcgacctt aaaagaggtt gatgcctttt attttgccct tgatgagatt atgaggggga
     9301 atggttggca atgcgcatac acggaacaaa cagatgatga ggatttagaa ggtgcaaagc
     9361 ggattatcaa acgatatgta gcaaatattt cactaaatta aaaggagaga aaatagatgg
     9421 caacagtagg atttgagagc gtcatttttg gcgtaaaaac aggtgcaggc ggcactctaa
     9481 aagaattagt agcagataag tcgaaaggcg gagcgatcga agctaaaatt actggattag
     9541 gcgcaacttc taacacaaca tacgcttcaa acgtaccatt cttcattgca agtaaagggg
     9601 tttcgtcgcc aaaagttacg cttgacgtgg cagacttaat ggataacggc atttacagcg
     9661 aaatcattgg cgctaaaacc gtggatggtg taaatgtaat tggttcagaa actgaagcgc
     9721 cttacgtgtc ggtagtcatg gttacagcga acaaagaagg aaaacgctta ttcatgggat
     9781 tggcaaaagg aaaattcagt catccagata tcgacatgaa aacagctgaa gacaaaggag
     9841 ttgaattgca aaccgattct atcgaagggg aattcatttc tgatgaacgt ggctatgtat
     9901 acttaacagc cgtagaatca gaagaaatga ccttacaaaa attcaaggac ttggtaaata
     9961 acaaagcggg ggagtagtta accctgcatc tacaccaacg acagatacag ggacaccaaa
    10021 agaaccagaa ccaaaaattg atacacaagg ttagccattt tttggctagc cttatttttt
    10081 tgtaaaaaca aggaggaaaa caaatgattg aattgcaatt gaaacttgac ggaaagaaaa
    10141 aaacattcaa acaacaagat atttccgcac gtgcaatgcg tgagtgtatc aaattttacg
    10201 agaaagcgga aaaagcagac ctaactgatt tagaagcaat tgattcaatg attgcaatta
    10261 cagcagatat tttccaagat ccagcagtta catttgatgc tattttagac ggtttgactg
    10321 cgagcgagtt agtaccggca ttagaaagtg tttttgaaca aatcaatgaa ctgggaaaca
    10381 atgaaaaaaa gcagacggcg agcaaaaaga gataagtttt tctgaagcta ggaaagcaat
    10441 ggatcaaatc tacaaagatt taatcgaatc aggttggacg atgagagatg tggacgaagc
    10501 cgactatcat tatttgttac acctttttgg agaagtggag agtggcgaag aatatgtaga
    10561 tggtgctgat ttcatcaaac aatttttatc ggctgaagac ttggtaaaac ttgaggaagg
    10621 aggtaaataa tggcaggaaa aggacaaccg gcaggaaata tcaagctagg gattagttta
    10681 gatagcacta attttggtaa cacgctggac gaaatcaatg cgaaagtcaa acaagctgag
    10741 tcgaatatgc gtgccaatct aaaggcttat gattcagcag gacgttcata cgaagcactt
    10801 agtcaaaaga cgaaagactt gtctacggtt atggaagggc aaaacgccaa agtaagagaa
    10861 ttaacaaagc gccgtgatga agcgattagc aagtatggcg aggaatcgaa acaagttgct
    10921 aaccttaaca cacagataaa caatgctacc gcaaaatata atgcttacag tcgccagttg
    10981 aatgacacaa aaaaagaatt ggtgtattcc aaaacagccg tcaatgattt atctaacgaa
    11041 atcaaagaaa atgaacgaca aatgaacgcc gaagtaaaag cgttgaaagc cgctggtgat
    11101 gaatctggtg cgtttgaagc aaaacaaaaa gggctagcca aacaaacgga attatccgag
    11161 aaagctatcg aagaacagcg caaagttgtg aaactgatgg ctgatgagtt tggcgattca
    11221 gcaaatgaaa ccgaagatgc aaaaagggca ttagaaaagt tagaacgaca aagccaaata
    11281 tctagcaggc aattagaagc actcaaaagc tccagcgatc aatcaggaaa aaaaatagaa
    11341 gattttggcg acaagtccac aaggtcagct aggaaactgg atgggctaaa agacaaatta
    11401 ggctcgctaa aaagcgcatt ttcgtttggt gcagttgctg gattagcgca taacgctatt
    11461 agcagtgtag taagtggcgt gcaaggcttg gttggcgaag cagtaaacgc atcggattca
    11521 ttgatgaagt tttccaaaac catggagttt gctaactttg ggaagtcaca gatagaaagc
    11581 tcgaaaaaag aaatgaaaga ctacgccgat aagacggttt atggtttaga agaaattctg
    11641 aacacaaccg cacaattggc atctaacggg attcctaact atacagaact aaccaaggcg
    11701 gcaggtaact tgaatgccgt tgcaggcggt tctagtgata cattcaaatc cgttgccatg
    11761 atgctaacgc agacggcagg agctgggaaa ctaacaactg aaaactggaa tcaattagca
    11821 gatgcgatac cgggcgcttc agggctgtta caagacgcta tgttgaaaaa cggagcttat
    11881 acaggaaact tccgtgatgc aatggcgcaa ggtcaaatca cttctgatga gtttaaccaa
    11941 gcgattgtac agttaggtat gaatgacgga gcagttaaag cagctacttc cacagataca
    12001 ttgagtggtt cttgggaaca gatgaaatct actgtaataa atgggttaca aagtatcata
    12061 gacaaagtag gcgttgaaaa tatcactggt ttcatcaaca gagtaacaaa agggattgaa
    12121 aattctattc ctaaaattac tcaatttata ggttggttga gagatattgg aacgtggatc
    12181 gttgaaaata gagagccact aacatggatt gtcggaatca taggcggaat tacattagca
    12241 gtaaaagcat tgaacgtagc aagtatgttg ctggcaatta ctggcggaac attggcagcc
    12301 ccttttgtgg cgattggtgt agcattaggc gcactagcag gtgctttggt gatagcttat
    12361 acaaaatctg aaacatttag aaatatagtc aatgcggctt ttacagctgt gaaaaacgta
    12421 gttatgagcg ttatcaataa tttggtggaa tactacaaaa tgttgtggag cgtgttgcag
    12481 tggctttggg aaaaaataaa agaatgggct tcatggattg gcaataaatt cattgaaatg
    12541 aagaacagcg ttgtgaatac ggttcagaac ctatggaatg gtgtgaaaaa cttcttcagt
    12601 aatggcgttg gagacacttg gaataaggta gttggctggg taaaaaacat tttcaacaaa
    12661 gcaactgaat tgaagaacaa agtttctgat gcaattggta acctgtggaa cggtatcaaa
    12721 gacacattcc gtagaggcat tgatacggta ttcaattggt tttcagaact accgacgaag
    12781 atgaagaatg ccattattgg cggtaaaaat gccattgttg atgcgttcaa aagtattttc
    12841 aacgcagcac ttaaagcgat aggtaaacca gttaacgcaa tcatccatgg agcttcatgg
    12901 gtactagaaa aactgggtgc tgacaaactc gaagaatgga aagtgccaca atacgcaaaa
    12961 ggaacaccaa acggaggtca tccgggcggg cctatgatgg taaatgacgg tagaggtgct
    13021 gaagcggtaa tcacacctaa cggacaagca tttatcccac gagggcgaaa tgtagtgttg
    13081 aatgcaccaa aaggcacaca cgttctaaca gctgaagaaa cagcttatat gactggaaac
    13141 aaagcaccaa gatatagata cgccaaaggt acaggctttt tcggaaatct atggaacaac
    13201 gtcaaaggat ttgctggaga tgttggaaac aagctgaaag atgtagtcgg cgatgtatgg
    13261 gattttgtaa cagacccggg agcgttggct aggaaagtgt taaatggtct tggcgtactg
    13321 gaagggcttg tcaaatatcc tttagatgtt ggtaaaggta ttctaagcaa ggctaccgaa
    13381 gcattgacga acaaaatcac agaactattc agcagtggca gtttagacac ttcaatgggc
    13441 atgcaaggcg tttacaaata cttggcggac gttgcagttg cagtaatgaa gaagtttcca
    13501 ggctttgtgg caactagtgg gtatagacca ggtgacccct attcgcatgg taaacgtaat
    13561 gccattgata ttgcactacc tggtgtcaca ggaggctcgc cacgctacac agaagcagcc
    13621 aattacgcat ttgagaagtt tgcaaacaaa atcggctatg ttatcacaaa tggcaaggtt
    13681 cgtgaccgtt caggacaatc aggtacaggt attcacaatg attggagacc atggcccgat
    13741 ggagatcact atgatcatgt gcatttaaac ggtgtgaaag acccacaaaa cactcaaatt
    13801 tcaggagata gcgtgggagg cagtggggta gaaagatggc gcaatgtagc aattagagcg
    13861 ttgaaaatga ccggtcaata cagtactgca aacttaaatg cattactaaa tcaaatgcgt
    13921 acagagtcaa atggtaatcc taatgcagtt aacaattggg atattaacgc caaaaatgga
    13981 acaccatcaa aagggttgct ccaagtgatt gacccaacat tcagacagta tgcaatgcca
    14041 ggattcaaca gcaatatttt tgacccacta tctaacatct tagcttcaat cagatacgca
    14101 ctatcaagat atggctcact aacaaatgcc tatcgtggag ttggttacgc aaacggtgga
    14161 attgtaaacc aacatcaaat tgcggaaatc gcagaaggaa acaagccaga aattattatt
    14221 cctttagata aggctaaacg atcaagagcg atgcaattat tgtctatcgc aatggacaaa
    14281 ctaggagttt ctcctaaaac ttatggaaat gcgacaactg tttccagtga ttacgaaatc
    14341 ctagaagcca ttgaaaaaca ggcggcaaca acgaatcagc tgttatcgtt attgctggca
    14401 tttttcaaag gaaatagccg aactgataga gatttagctt tagatattca gaagatcttg
    14461 gttaggagga tgtagatgcg aactgtatta ctgagaaata gaataaacga agaaattgat
    14521 ttgtctacgg aggattattt tgctactggg ttgagtaata tggggtttga agtaaaaaaa
    14581 gaacatgtgg gacagtgggg gaatttcaga gaaagcagtg agaacgttga aatatctgaa
    14641 tttcagtcat ctgtaatcat ttctgtgcat gggtttcgag aaaaagaact gtacaattca
    14701 cttgtgcagt tcctatcgga aggtccgttt gaactggaat ttgcttttga cggcgaaaca
    14761 atggtaagaa gatgcagtct aaaatcttta agtaagactg aaatcgatcc gaaaacatcg
    14821 ttactaacag acactttaga actatatttc acatcaaact ggtattccgt aaaacgcgaa
    14881 aaattaattc agcgaccgaa tgtagtgaaa acacgtggta aggtttttcc gtataaaaga
    14941 tcttatatct acactcaaaa cttgtgggag aaaaaaggtg tattcaaatt caataataat
    15001 tctgtatacc taacgaatag caaggaacgg atgtccccgc taaaaattcg tgtgattggg
    15061 aagtgttcaa atccgtattg ggaagtaatc caaaactcac aaatcatcgc aacggatgga
    15121 tacttcatag atatgactga aacacagact ctagaagtat caagcctttt tgaagataca
    15181 acggcgattt taaaagatat tgcaggggta gaatcttctg tctaccaaca acaggattat
    15241 acaaaaacta attttgttca ggccccgact ggagaattca gcattgtgtt tcatgttggg
    15301 ggggcagacg tagagattga gttatacgag gagcgtgatc tgttttgatt ttagcagtca
    15361 cgctttttca tcgtgattta atgctttata acgaacattt attctctaac agttttgaat
    15421 ttggtgcgga cgagatcaac gaagaggcta gtagctttac gatggataag tacgttcctg
    15481 taaaaacagg cgattttcta ctagcaaaat atattcctag tggaaaattt gcatattttg
    15541 gtgtaattac gtcgcaggaa gacgaaaaaa tcagttgtaa aagcttactt agtttagctg
    15601 atagtgagat accgactgca cgtgtgtcag gagataacta cgaagagcat atccggcggt
    15661 tgattgaata ctatttgctg aatgatccaa cgaaacaact aaaagatatt ttagacgtca
    15721 aagcagaaag tgcgacctct cattcgtatc aagctaccga tacgaataaa cacaagttaa
    15781 gtgcgtatat tctcaatggt ttcaaaaaat acaacgtaaa atggtatttc aagggaattc
    15841 aaaacagaaa aatctataca ggcatacgtg ctgtaaatga atcaatttac attaaagaca
    15901 attcttctga atttagcgat tgggatgtgt ttgttcaggc gccgggcgct ggaaacgaga
    15961 acaagctatt aatcgttgat aaagcaatga aagatataga gaaaccgata atactgtcaa
    16021 catggtattt ggacgaagaa aacaatttga cacaagatgg atcgaaagaa aatatcacga
    16081 aaccaactgt caatttggtt aatatctacg atcaaaccgc agaagataaa gcatcctacg
    16141 aagatgtggc aaaatcagag ttgaaaggca atacgtattc gcatgaaatc aaagtgaacg
    16201 ttgtaagaaa tgcaaaaaat ttgaatgtcg aaacgattga aacagggatg tttgccacga
    16261 tttcttataa aggaaagata tacaagtcgg ttttgacagc ttggcgaata tcaagtgata
    16321 aggagtttgt ggaattgact ttcggaaaca taagaagtcg ttttatggat tattttgaag
    16381 ataatggggg ataaaaaatg gttagcaatg tggatggata tcaatttgaa aacgtgaaag
    16441 taagcgcaga aaatgatgct agactttatc acgttttata taatcggaaa aatcaggtta
    16501 ttgatggtta cgatcagtct atgaatttat cttcaagcgg attaacagta aaagttgctg
    16561 caggagcagc gattattcaa ggtcgtatgg tcgttgttcg acaagaagaa agtataacag
    16621 ttccagcaaa ctcaagtggt tatatagcat taacagtgga tttgacacaa gaagttatac
    16681 ctggatctat tcttccagaa tcggaagaat atgaatggac taataatcaa gtcaagctag
    16741 aatttataac aaaagttata aaaggtaatt taaacaatgg tgataaggtc tataatttac
    16801 cactatgctc agttacttct actggatcaa ctgtttcaat ctcaaagata tcggatagtt
    16861 acgagctgac tctctctaaa ggagaaattt tgtggagtgg gactgcgtta atgcatgata
    16921 ctcaaactgt ccaaccttca aaaaaaatgt ggcagacagt ttcaggtttt ttattagtat
    16981 ggctcccata cgaaaacggg caagcaattg gggatagata tgtaactacg cctttttata
    17041 aagagcgtgt aacttttact aatgttttag gagaaattgt ttcaggattt gatgactatc
    17101 acaaaaagtg gtttagtaaa cgaataaact ataattcgaa tactaatata tttacaggtg
    17161 cagcaagcaa tgcaagtgga gataacgcaa atatggtgct taggtatata gtttcttttt
    17221 agttaggagg tatggaagag tggcaaattt agaaattaaa ttatctgcaa ataagagaca
    17281 gccttatcta cgtcaccgtg ttgttggtag agttggtgat ggggggctca caacaatcaa
    17341 tgtacaactt cttgaggaag atgaaattac accttttgta attaatctaa acggtacttt
    17401 gaaatttgtg ggcgaagttt caaacggtaa ctataccgag ggagaaccag aaataatcga
    17461 ttcgactaat gggttaatta gttacacgtt cactaagtca aatttcagca cgagtcatca
    17521 attcaaacaa gcatattttg aatatgtaga tcctaacggc aaaaaagtaa cttttcagaa
    17581 cttcatcata gacgtgttag aacgagtaga tattaattcg gagcaagcga aatactatat
    17641 ttcttcattg gaaaaattac agagtgaaat gcaaaccact ttcaatcagt tcattagtga
    17701 taaacaggtc caatacgatc aaatctactc gaaatataac gaattagtaa gattgataaa
    17761 tgaatcagat aagcaagtaa atgatcgtat tgataagaca aatgatcgta ttgatcaaac
    17821 caatcagcaa atcggcgatc tcggcaagct gaaaaagatg tacagtaaca gcatcgactt
    17881 cggggactat gattatagtg ggaatccgaa ccttagcgct aaacttaatg cttcaagttt
    17941 ttctttaggt actggcgcaa cagtcgcgga tgataatgat gagattgtgt ttaccttaga
    18001 tggcacaaat caactatcga agtacgctag caaagcgcaa gtgccggtag cagaagggaa
    18061 acaatatacg attagttgtg aaattatgtt agaagatggg ttcactggcg acccttcagg
    18121 aatacgtctg caacacgcat atttgccagg cggggttgtt gttttacaga cagagacagt
    18181 acctaaaaat gaattgaata cgtggcagac gcttatcgga acgcgaacgg taaaatacac
    18241 ctctgacgta ccaaatgaat ggtacccttt gtttagagac atccgaacac ttaaaccgac
    18301 cggtaaagtt agactaagaa aaattaagat tgaagaaggc tcaacagcca ccccatatca
    18361 gccaaactta cttgatgacc cttactggct aggtaaagcg cctttgggtg agaatattgc
    18421 taataagtct gttacgtttc caatcaaatc tagcgcctac agcctatacc aagctaacat
    18481 ggaagaagaa tttgttttag gtcaaaccta tacaattacc atgaaggcaa ccaaaccacc
    18541 tatccaaacg ttcattgttt acaacgagga tagtggagat tatagatatg gtaacttaga
    18601 gccagtagaa gggttagttg atacatgggg tctgactttt acaccgcaga aggttggagt
    18661 taactacccc aaacggttaa ctattatcca gtatccccaa tcaacaacag gtgcatgtca
    18721 aattgactgg ctcaagatcg aaaaaggcaa tactcgaacc ccgaatatta gtgagtataa
    18781 atatcgtggt actggtatgc gtgattcaaa caatccaaaa gattatgttt gggatctagc
    18841 accagaatat gtcgaagata atttggccac agatattaaa atttctgaaa ttactggtaa
    18901 agcaaacaat tataccgatg ggaaagtatc ggagattaat tcgcagttga ctgcttcaat
    18961 taatgaagta gacaccacag ctaaggatgc tcaaacaaaa gcgaatgcta atgcgactgc
    19021 tatagatgaa ttagacaata agatcgatga acgcattaat gatacagcta ctaccacatt
    19081 aacagttaca aacgggaata ccggatcagc aaagctttat cgtgaaggaa aaacagtttc
    19141 tatatatttt gtggctttaa acggaaaaag cagtggtgga aatgattcaa cgatactaac
    19201 aattccagaa ggctatcggc caccaattag ttttgagcaa ctggttggct cgatagaccg
    19261 ttctactttg aacagtgctc agttatctat tggtgcagat ggagccatta aatggcgaag
    19321 aaactcaagt tatggatcgg attatacctt tgcaattact tacacgattt agaaaagcgt
    19381 gaatcgatat gaaggcagca tatagaccaa ttgaacctta cggattcgag caaatcattg
    19441 tgaatgatga agaacattta ccggaagaat gcacagaagt cgaaccaccg attctaaatt
    19501 ggaaaccgaa attcaattac tgggagggaa ataaatgaaa aacatttgga aatatggacg
    19561 tactggcgga gagtacgcag gaaaagtatt ggacgacatg cttgtatccg ttccttacac
    19621 agatcagcca ccgcttgaag gaattcgtgc tgatggcgaa ccgttaacaa tcgctgatca
    19681 aatgtttgat cctaaattga atcaatggat tattttagcg aacgcactag atcacaacga
    19741 tttaaacaat ctcaaagcaa tgtatgagtc gttagaaaat gagaacggcg atttaaaaca
    19801 gatcaatgcc aaactcatgc taagcgatgt agcaattaaa caggaaaata ctgcattgaa
    19861 agaaaaagcg gatagtttag cacaaatcaa ttcaaaaatg atgcttgctt cgttacaaaa
    19921 tagcaaagac atttcagaaa ttaaagagca actaaatcca gcttcaaagg gaggtgagta
    19981 gtatgtttag ttttagcgat gtgaaaatga tgtatgattg gggctgtttt actgacgatc
    20041 aagttcgact attcgttcca ctatgcatta cagacgaaga agcagataaa atcattagca
    20101 aagaagaaag cgcatcttaa gtgatgcgtt tttatttaag gtaaaggagt tgtcacatga
    20161 tcaatttagg ggaatgggga acaatcgcag gatcaattac tgcgattgtt tctttgattt
    20221 tattagtaat aagaccagtc actgcatctt tctcgaagat tactgaaact ctttcaaaag
    20281 taagtcacaa tttagatttg ctgactaaag atttagaatc gagcaaatca gatcgattga
    20341 tgattcatga agaactaaag aaacacgatg aaagattaga tacacatgca gaaaaattgg
    20401 tagaacacac acaacaaatt aaaactttat ttagagaaag gtctcggtaa aaaagaaagg
    20461 agttaagaag aaatgatttt acccgataag tattatcaag tcattaaatg gacagtttta
    20521 acagtattgc cagctttatc tgtattagta gccacattag gcaaagcata tggatggaat
    20581 ggaacagata tggcagttct gactatcaat gcagcagcaa catttttagg tgttatcact
    20641 ggtgtgtcgg cttataattt gaaaaaatag gaggaaacaa atgaaaaaga aaattactat
    20701 tactgcgatg agcctattaa cggctctttt tttattgccg attaatgggt ttgcctatac
    20761 gattaacaat gaatttaatt taggtgtaaa cgaaggtagt tctcaagtag caaataatca
    20821 gtacatttta ctgcatgaaa cggctaatga aacagcaaca ggacgcaatg aagcgcagta
    20881 tatgcaacgt tcatggacta gcgcttatac tgcttatatt gtgggagacg gcggaattgt
    20941 ttatcaagtc ggtcaacctg gttatgtaca gtacggtgct ggttcgtatg ctaatgcaaa
    21001 tagtcctgtg cagattgagt tacaacacac acatgataaa gcaacgtttg agaaaaacta
    21061 caaggcatac gttgaattag ctagagattc agcaatgaaa tatggtattc cacttacact
    21121 agacacaccg tataatcaac cagggatcaa atcgcattta tgggtaacac aaaatatttg
    21181 gggcgatcat acagatcctt acggttatct ttctgaaatg ggcgtaagta aagaaaaatt
    21241 agcctatgat ttggctcatg gatttaccga tgaaaatccg acaacttcag atgataaacc
    21301 agtcattgat ccaactcgag caggtgctgc aaatcctacc ctgacagatg gaacaaatta
    21361 cgcccacatt gatcagttcg gagaaatcga aaacgcaaac ttacatgtgg ctggttggca
    21421 catcgctaac tataaatacg agtatatctt cattatggat tacaatactg ggaaagaatt
    21481 agctcgagta aaagctgatg gaatatatag accagatgta aatcaagctt ataatacttt
    21541 aggaaatgtt ggctatcatg tatcttttaa catgcgcaac ttccctaata agaaagtcta
    21601 tgtaatgatg cgggcaacga atgatccaga agggaacact aaaggcggag cacaagattt
    21661 tcatgataaa cgctggtatt taaatattcc gcaacgataa aaatagcccc tcgtttttga
    21721 ggggaagtac ataatgcaaa tttgtccata acttattgat tatcttgtaa aaatgcggta
    21781 atttaatagt tagtgagaag aggtgcttaa ttatagttaa aaaagaggaa atagaagcag
    21841 catgtaacca agcaaatgtt aggtttattg gagaagcttt atctggatat cctaagtata
    21901 aatacttaca caactggtta caaagtaaaa gtttttatct taataaagaa agatgcatgc
    21961 ctaataaaaa ttatagggtt tataaaagag gaactattgt atatgttgat tttggggtga
    22021 acgtgggtta tgagttatct ggtaatcatt ttgctattgt tttaaataat aaagataatt
    22081 cgaaaaatgg tgttgtatgt gtagtaccaa tctcttcaaa aaagaaaagt aattatgtat
    22141 ctgtaggaaa aatattagaa gttgctagta ttaaacaatt tataagccaa gctgataaat
    22201 taaaagagaa acttaggata attattttac tttcattaaa tagaggcatc attgatgaaa
    22261 gcgatttgaa tagttttatt aaagatattg aagctaaagg tgaaaagctt tcagtggaag
    22321 aagtagaaaa acgagctgta aaacataatt tggtttgcga gacaagggaa caagtaatta
    22381 aagaaataaa atcattatct gaagatatgg taaaatatca gaaggtgttt aattgctaca
    22441 agaaatatac acaagaatcc tatgtaatgc cacttaatat ccaaacgatt agtaaaaata
    22501 gaattagaag aattaacaag tttgatcctt ctggaaatat gaaggcacct ggaaatgtcc
    22561 tcaatgaagt agatgaaagt ttaaaaaaat attttacaaa gtaaacgata tttttgttga
    22621 catttttctg ttcgttagtt accatgtagt tatagaagga cgtaagcgcc tatttttaat
    22681 gtacacatcg ggacgtatgc gcccacatag aaacatagtt gagagacatc tatatg
//
LOCUS       DADVXV010000045        22722 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.046, whole genome shotgun sequence.
ACCESSION   DADVXV010000045 DADVXV010000000
VERSION     DADVXV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.046"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            158..1897
                     /gene="yfcC"
                     /locus_tag="KB969_001631"
     CDS             158..1897
                     /gene="yfcC"
                     /locus_tag="KB969_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBB6869618.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2054..3238
                     /gene="iadA"
                     /locus_tag="KB969_001632"
     CDS             2054..3238
                     /gene="iadA"
                     /locus_tag="KB969_001632"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBB6869619.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3349..3552
                     /locus_tag="KB969_001633"
     CDS             3349..3552
                     /locus_tag="KB969_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBB6869620.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3653..4315)
                     /locus_tag="KB969_001634"
     CDS             complement(3653..4315)
                     /locus_tag="KB969_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869621.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4328..5830)
                     /locus_tag="KB969_001635"
     CDS             complement(4328..5830)
                     /locus_tag="KB969_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869622.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6378..8057
                     /locus_tag="KB969_001636"
     CDS             6378..8057
                     /locus_tag="KB969_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBB6869623.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8184..8663
                     /locus_tag="KB969_001637"
     CDS             8184..8663
                     /locus_tag="KB969_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBB6869624.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8882..9562
                     /locus_tag="KB969_001638"
     CDS             8882..9562
                     /locus_tag="KB969_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBB6869625.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9570..10901
                     /locus_tag="KB969_001639"
     CDS             9570..10901
                     /locus_tag="KB969_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBB6869626.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10916..11878
                     /locus_tag="KB969_001640"
     CDS             10916..11878
                     /locus_tag="KB969_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBB6869627.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11989..12327
                     /locus_tag="KB969_001641"
     CDS             11989..12327
                     /locus_tag="KB969_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBB6869628.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12406..13113
                     /locus_tag="KB969_001642"
     CDS             12406..13113
                     /locus_tag="KB969_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBB6869629.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13216..14697)
                     /locus_tag="KB969_001643"
     CDS             complement(13216..14697)
                     /locus_tag="KB969_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869630.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            15006..15542
                     /locus_tag="KB969_001644"
     CDS             15006..15542
                     /locus_tag="KB969_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6869631.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            15620..16990
                     /locus_tag="KB969_001645"
     CDS             15620..16990
                     /locus_tag="KB969_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBB6869632.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            17057..17392
                     /locus_tag="KB969_001646"
     CDS             17057..17392
                     /locus_tag="KB969_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869633.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(17473..18330)
                     /locus_tag="KB969_001647"
     CDS             complement(17473..18330)
                     /locus_tag="KB969_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869634.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            18436..18951
                     /gene="tadA"
                     /locus_tag="KB969_001648"
     CDS             18436..18951
                     /gene="tadA"
                     /locus_tag="KB969_001648"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBB6869635.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            18974..19058
                     /gene="ffs"
                     /locus_tag="KB969_001649"
     ncRNA           18974..19058
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KB969_001649"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            19268..20653
                     /locus_tag="KB969_001650"
     CDS             19268..20653
                     /locus_tag="KB969_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6869636.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSCLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            20690..21367
                     /locus_tag="KB969_001651"
     CDS             20690..21367
                     /locus_tag="KB969_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBB6869637.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            21375..22139
                     /locus_tag="KB969_001652"
     CDS             21375..22139
                     /locus_tag="KB969_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBB6869638.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            22141..>22722
                     /locus_tag="KB969_001653"
     CDS             22141..>22722
                     /locus_tag="KB969_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBB6869639.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVL"
BASE COUNT         7397 a         3819 c         4851 g         6655 t
ORIGIN      
        1 aaaaaaataa tcatacatag gagaaaaaaa acaaaataga aaaaagtgat tttctaataa
       61 attattcatg tggaaatgtc atttttactg tataattcat ttgattatcc attttttatt
      121 catcaaaatt actgaaaaaa gaaaggaaga aataaatttg aagaaaacaa attcttcagg
      181 aaaaccgaaa cgcgacttca ctaaattatc gacaccccat acgtatgtca ttatttttgg
      241 tgtagtcatc tttgcatgga tactgacttt tgtcgttcca gcaggaaagt tcagcacgca
      301 agatattgaa tacaaagatg caaatggcga aacaagtact cgtactgttt tacgtcaaga
      361 ttccttccgt tatgcttacg agctggataa gtcgtatgtg tttgatcaat tagaagaact
      421 gcaagatcat ccagcagaac gtgaaaaact ggatgttccg gaaaaaggat tggaaaaagt
      481 cattgctgac ggagaaaaaa atcttacgca ggaaaaacta gatgaaatct ccttgacaga
      541 tgatgtgctt tacgatcagt acggcgaaaa tatctatgat acttctaaaa aattgcataa
      601 aacagccaaa atatggggaa cagatgattt tggcggcttt ggtttcttaa attttgtttt
      661 tgaaggacta gtatctggag ataagtatgg atctgctgta gggatcgctg cattgatcct
      721 tgttgttgga ggtgcttttg gtattattat gcgtaccgga gcgatcgacg caggtatcta
      781 tgcgtttatc agtaaaacta agggactgga gcgtttagct ttaccgctat tattctttgc
      841 tttttcattc ggtggcgcta cattcgggat ggcagaagag gtaattccat tctcaatggt
      901 gatggttcca tttgtcattg cgttaggata tgactcgatc gtagcagtaa ccgtgactta
      961 tgtcgcatct caagtcggaa atgcgacctc ttggatgagc ccgtttagcg tagcggtggc
     1021 tcaagggatt gctggaatcc ccgtgttgtc tggtgcgaca ttccgattga ttatgtgggt
     1081 agttgttact gcattagccg ctggttatat gatgatatat gcagaaaaaa tccgtaaaaa
     1141 accagaaagt tcgttgactt acaaatcaga tgattatttc cgttctcata tcaaaaagac
     1201 atctgatgaa aataaaaaat tcatgcttgg gcataaattg atcttattag agatgttagt
     1261 tgtccttgtc tggatcgttt ggggcgtgac tcaaaaaggc tattacattc cagaaatcgc
     1321 ttctcaattc tttgtgatgg gattagttgc tggaatcatt gctgttcttt tcaaattaga
     1381 tggaatgaaa gtcaatgaca tcgcttcttc tttccaatct ggtgcagctg atttagctgg
     1441 tacagcaatc gtagtaggta tggccaaagg gattcttctt gtcttgggag gatctgatgc
     1501 atctgttcct tcagctttga atacgatttt gcatgggatc gggacggcgt tgaccggtgt
     1561 tccagctgtc attggtgctt gggcgatgta catcttccaa agtttgttca acttggttgt
     1621 tacatcaaat tcaggacaag cagctttgac tatgccaatc atggctccac tggcagattt
     1681 agtaggtgta tccagacaag tagcagttct tgcttatcag cttggttcag gttttatgga
     1741 cgcttttaca cccgtatcag ccagcttgat tggtgtgcta ggtgttgcac ggatcgaatg
     1801 ggcaaaatgg gcaagattcc aaatcaagat gcaaggattc ctgtttgttt taggaactat
     1861 tttcatcatg attgccattg caataggtct gcagtagtac tggagacctg taaataaaaa
     1921 agtaatccaa acagtagata aggactccaa gaaccgtcat tttacggtaa aatcaaagga
     1981 gtaaagatcc tatcgtttgg attatttttt aagatcctat catcagttat acttaaagaa
     2041 agaggaaaaa tgtatgaaaa tcattcgaca aattgaagtg tttgcaccag attacttagg
     2101 aaaaatggat gtactgattg ccggtgggaa gattttggct gtagaagaac agctagaagg
     2161 cggctacgaa ggagtggaag tagaagaact ttcaggtgag ggaaaagtac taaccccggg
     2221 tttcattgac tgtcatttcc atattttagg tggaggagga gaaggcggtt atcaaaatcg
     2281 aacgccagaa gtcacattga gccaattgac tacagctggt gtaacgacag ttgtcggttg
     2341 tttgggaaca gacggagaag gtagagatat gactgcgttg atcagcaaag cgaaaggtct
     2401 ggaagcagaa ggaatctcca cttatgtata cgaaggttcg taccgattgc cggtaaaaac
     2461 agtaacagat tctatcatca aagacttttt gacaattgat aaaattatcg gaatcggaga
     2521 aatcgcagta tccgatcacc gttcttctca gccaagtttt gaagagttcg ctcgtgcagt
     2581 agcagatgct cgtgtaggag gcatgttatc cggaaaagct gggatcatca atgtccactt
     2641 aggcggagga aaaagaaagc tagagctatt gacacgaatc gtagaagaaa cagaaattcc
     2701 gatcacacaa tttttgccta ctcatgcaaa tcgcacacca gaattatttg aagcttgcgt
     2761 ggcatttgcc aaacgtggtg gcacgattga cttcactgct agcgaagatc ctgatttttg
     2821 ggagaagaca gatggtgaag ttcgcttcag caaagcactg aaacgattga tcgaggaaga
     2881 tgtttcttta gataatttca cgatgacctc agatggacaa ggaagcttgc cttattttga
     2941 tgaaaacaat catttcctag ggttaggagt aggaagtgcc aaggcattgc tagtagggat
     3001 caaagaagct gtgcaaaaag aaagtatccc tttggaaatc gccttacgag ctataaccag
     3061 taatccagca cgtatattga aattggataa aaaaggaaaa atcgaaattg gtgctgatgc
     3121 agatctgtgt atcttggata aagaaacgct tgatattgat acagttatcg ctaaaggaga
     3181 aataatggtc caagaaaaag aagtcaaagt atgggggact ttcgaaaaaa gtttttaatc
     3241 aacagctcta actatctttt ttagaaaacg agcgttctgt ttgtctgtat ctgttgttga
     3301 tgttaccctg aaggtagatc aataaacaaa ctaagaggag gaagcacaat ggcagattta
     3361 aaaggacgtt ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga agcatacggc
     3421 aaagcaacag acgacaagag caaagaaaca gaagggaaag cacaatcact aggtgctgac
     3481 atcaaagaaa aagctcgaaa tttaggcgac gaagtcaaag acaagttttc tcgaaaagac
     3541 gaaaaaaaat aaaaaccact tattactaat tgaatcaagc aaataaaaaa tccgaaccat
     3601 atctgcgaga cagatatggt tcggattttt tatttgatca ttatcctgtt ttttaaactt
     3661 cgattttttg aaatttttta ttttttagtt caaagacttc atcacagctt tttgctactt
     3721 caatctcatg agtcacgatg ataatacagc gattttgttc atgggcgatt tcttggaaaa
     3781 gtttgacgat atcttgtgaa gttgtttcat ctagatttcc agtaggctca tccgctacga
     3841 ttagttgatg ttcacagcag atagcacgaa cgatagcgac tcgctgctgc tgacctcccg
     3901 aaagtttggt cacctgtttt tttgctaata tttcatcaat tcctacacga gccagtcgat
     3961 ctaaagcaac ttgtcgataa ttctcttgct tggtcttagt gatttccatt gctgctatga
     4021 cgttgtctag agccgataaa taaggaagca agttgtaagc ttggaaaata atcgagacat
     4081 catttttacg ataacttctt aacccgattt tgttcagtga acgatcttga tagtatacct
     4141 ttccttcttt tggtgcatct agtccagaaa taagcgaaag aaaagtcgtt tttccagaac
     4201 cacttgctcc taaaatagcg tacatttttc cagcttcgaa attcagttct acatctttat
     4261 aaagcgcatc ttgcggatct tgataccaaa atcccaattg ttctgtccgt aacatcaaat
     4321 tcctccttta gtttaatagg atttttcttg ggtttaatct taatatccct atagaagcta
     4381 aaaagacaga aaacagactg attccaaatg ctactccggc taatagtccc aattgtgcag
     4441 gtttgacatt gatttccaat tcgctgactt gatcagaaac agcaaatgga ttattcgtgg
     4501 ttccttgttg accatcgcgt tgaccgcctt gttcttgtct gttacctggc atttgtccac
     4561 cgccaggagc ttgctggttt tgtgtcgtgg tttctgtctg ttggtcaagt agctgctgtc
     4621 ccacggcatt cgcgacgacg tttccgctaa gcgaagcaac tcctaatgca agaatcatac
     4681 aaatagccac ttcggtaaac aattggagaa tgattttact tctggattct cctaaagata
     4741 gcaagacgcc taactcatgc cgacgctccc gaatggtaat cataatgatc agagtaagta
     4801 tgataatacc ggctacagcc actagtaaaa caacattttt agaaaaactt gccacgttgt
     4861 ttaaaggttc caacattgac tgatacatgg aatcatttga ttgtaagcta aatgtatctg
     4921 tgtcgatcag cttctcagct tctttgagaa actcatccat tttatctgga tcagatagag
     4981 tgtaaatagc agaatctatc gtgttatcgt cagatgtccc atttagttca tttgcaaaag
     5041 tgtaagaagt gtaaagtgta ttcgacggat tcatgaagtt gaatttcata cccatactgc
     5101 cgcttgtttc gctggattca taaattcctt tgatcgtcat ttcataagtg gtatcttcat
     5161 cttcagtact cgtgattgtg aaagtatctc cgactgccag gtcatttgtt tctgctagag
     5221 tagaatcaat gactacattg tttgtgcctt tgtcgctgtc atctattcct tcaccatccg
     5281 tgatttttgc tgttccatca gaaaaattac tattttgtgc agttgctgac acaccactga
     5341 tttgaaagtc tgcttgagtc atttgcggat tcccgcccat tcctccagca ggttcaccgc
     5401 ctgcatcagt agtttctgaa ctgtcttcac ttgaatcaga actagtgatg gcagttattc
     5461 catcttttgc catagctgag gcggaacttt caaaggaata actctttaca ttatctaatt
     5521 cagctatttt ttccgcgtcc gttaaggaaa ctggtgtaag agaaaaactg cctggatctg
     5581 gacgttcttc agtggtagaa ccgcttgaag aagtttgttc ctgtttttta aatgaagctt
     5641 ctcgattggc acttaaagtc actgttgctc caacttcttt ttgtgcttga ttcgctgctt
     5701 cttctgcagc gcttcgaatc gtgaggccag ctagcacaaa aataagaatg gctgtgaaca
     5761 cggcaaacaa taacaatgaa cgtccccatt ttacttttgt acttttccat gcacgtttca
     5821 taaaattcat attttgcatc cctcctagta gatgcatttg ataatagaca acctatctta
     5881 aagctagctt aaatcttatg ctgtttgcac accatcaaca tgaggttctg tatatataaa
     5941 aagtcactat agttattgca aaaaatgtgg taaaatgaaa aaagtatgtt tcaaaccgac
     6001 gaagaagaaa tgaaagagga atagcaaaag aaatcctaga tgctacagag ggatttttac
     6061 gtgcatagtt gttctaacaa ttgctgatac tagcgattta gtttatttgt tgtataataa
     6121 tggggaacag ctgaatactt atataagtat tctggctata gcgtttcgca aaagatccat
     6181 tttgttaatg aagtatatcc aaaataaaat gcccatccaa ctgtcagaac gcggatgtgc
     6241 tggtaatttt cctgctgatt ctccataagt tgagaaatag tgattttgca tatgcttcat
     6301 tggaatggct catatattta gataaagaag aaaatcgaca tctttaaact tggatgtcat
     6361 aagaagaggt gaagtttgtg agtaccatta aaattatccc attaggcggc gttcgtgaaa
     6421 atggaaaaaa catgtatgtc gcagaagtgg gcgaggatat ttttatttta gattgtgggc
     6481 taaaatatcc tgaaaatgag ttgttgggga tcgacgtcgt aatccctgat tttacgtatt
     6541 tagaagaaaa cattgatcgt gtagctggtg tctttttaac acatggacat gcagatgcga
     6601 tcggggcact tccttacttg ttgtcaaaaa tttctgtacc agtattcggg acagagttga
     6661 cgatcgagtt agcaaaattg aatgtcagtc gtaatgaagc agccaaagga tttaaggatt
     6721 tccatgtggt agatgagcat acagaaatag actttggtga aacagtagtg agctttttcc
     6781 gtaccactca tacgatacca gattcagtgg ggatcaatct gaaaacaaaa gaaggtagta
     6841 tcgtttatac gggagatttt aaatttgacc aaacggctat cccaatgtat caaacagatt
     6901 atgcacgatt ggcggaaatc ggcaaagaag gagtcttagc cttactaagt gaatcggcaa
     6961 atgcagaaaa tcctcagcct gtagcttctg aagcccaaat agcagatgaa gtatttgata
     7021 cgatcaaata ttgggaaggg cgtatcatcg tcgcttgtgt agcaagtaat ttgcaacgag
     7081 tgcaacaagt attggatgca gcagaaaaag cacaacgaaa agttgtcttg actggtcaag
     7141 atttcgaacg aattattcgc acagcgatgc gtttagaaaa acttcaatta ccaagtgaag
     7201 atctgcttgt tacgttgaaa gacatgaaaa actatgatcc agaagaactg atcattttag
     7261 aaactggccg aatgggtgaa cccatcaagt ctctgcaaaa aatggcaaac ggtacacacc
     7321 gtaatgtcaa gattgaagaa ggagatttgg tttatatcac tactacgcca agcatcgcga
     7381 tggaaaccat cgtggcgaaa acggaagata tcatttatcg agctggtgga acagtgaagt
     7441 tgatctctga gaatatgcgc gtttctggcc atgccaatcc taatgacttg caattaatga
     7501 tcaatttgat gaaaccaaca tattttgtgc cagttcaagg agagtatcgt gaattagctg
     7561 ctcatgcaga tttggctcat gcagtaggga tgccatacaa aaatatctat attactggac
     7621 gcggagacgt gctggaatat aagaacaagc gtatgagtgt tgcaggaact acaagtgcag
     7681 aaaatgtaat gattgatgga ttaggcatag gtgatatcgg aaacattgtt ttacgtgatc
     7741 gaaaaatctt gtcagaagac gggattttcg tagcggttgt cactatcagt cggcgagaaa
     7801 agaaaatcat ttcaaaacct caaattactt cacggggatt cgtttacgta aaagctagcc
     7861 gtgatctgat gaaagaaagc agcaatatga ttgaaacaat cgttgagaaa catttagaaa
     7921 gcaatgattt tgagtggagc aaattaaagc aagacatccg agatcaatta ggccgttact
     7981 tatttgaaca aacaaaacgc cgcccagtga tcttgccagt cattatggaa gctactcaac
     8041 gtcgaaataa aaaataaaca aaaagagtaa gatgaacctc tctatagagt gctcgtcttg
     8101 ctcttttttt gcgaaaaaca aataattttt gaatacagca tccctcgctt tataataaac
     8161 gatagaataa agggagtgaa tcaatgatga gtcaaacaaa agtcgaacgt tatttagaag
     8221 aacaaaagat cagctatcaa ccacttgatt ttagtcatgt ggtagaagaa tctttcacag
     8281 aagaactaca aaaaagaggg attgatccag ctttgatatg taaaactctc gtagtgaaag
     8341 gaaacaaaac tggggtgatc atcgcattga ttcctttgaa cgatcactta gattacaaaa
     8401 aaacgagaca agtgacgaaa gatcgtaaag ttggttttcc tggaatggat tttgtattaa
     8461 tgcatacagg atatccccac ggagcaaaca cccctattgg aataaaactc gcacatcctg
     8521 attattgttt tttagcagac agttctttaa aagaaaaaga agaagtaatt gtgtcaagcg
     8581 gtgaaatcgg gagaagcctt cggataaaag tagccgattt agaaaagatc gtccatccta
     8641 tttacgctga tttaattagt taagggacga gaagagaagc taagcagagc agagacctca
     8701 aacttgagat tatatctgct tggtacttgg tgcatcctgt attatctgtt acaattgctt
     8761 tgtacatact gtactatcaa tccaatgaaa atatatttag cagctatatt ttttcattga
     8821 tgtgcaagtg atgaaatcgt ttttaataaa aaagatacag agaaaacgcg aggtgtaaaa
     8881 tatgaaaatt acgtatcatg gacattcctg tttaacaatt gaaatggaaa atggccaacg
     8941 cgtgatgatt gacccgttta ttacaggaaa tccattgaca gacttaactg cagaagaagt
     9001 aaagacagat tggttgctga ttactcatgg tcatagtgac cacataggag atatgattcc
     9061 tattgcaaaa gaaaatcaag ccacaattat cagtattgtt gagattgctg attatgcgaa
     9121 cagcagagga gtagattcat tcggtatgaa tatcggtgga aaacatgcgt ttccattcgg
     9181 cgtggtaaaa ttcgtacatg cacagcatag ttcaagctat gaagtagacg gtatcgttca
     9241 gtatatgggc gagcctagcg gaattattat tcaagcagaa ggaaaaacga tttatcatgc
     9301 aggggatact gcttatttca gtgatctagg attgcttgca gaagaattcg atattgatgt
     9361 cgctttcttg ccgattggcg ataactatac gatggggcca gaagatgcag caaaggctgc
     9421 gcaaacaatt cgtgccaaga aagtagttcc aatccattac aatactttcc ctgtcattga
     9481 acaagatccc gaatcttttg tagagttact ggaagatagt gaaggaaaaa taatgagcgt
     9541 ctcggaaacg ctggaagtgt aggcagaaaa tggcgacaaa acatgatttg attttagaat
     9601 atattgaaag tttacctgtt ggcaatcgaa tttctgtaag aagcatcgca aaagaattga
     9661 atgtcagtga aggaacagcg taccgtgcaa tcaaagatgc agaaaatgtc ggactagttt
     9721 caacaattca acgagtaggg accatccgta tcgaacgcaa attaaaaaaa catattgaac
     9781 gtttgacatt tggcgaggtc gtcaggatca ttgaagggga cgttttaggc ggggcggcag
     9841 gattagacaa ggtcttgaat aaattcgtca tcggcgcgat gactaaacat gccatggaac
     9901 gctatattac gccaggatca ctaatgatcg tcggcaaccg ggcggaagtc caaaaattag
     9961 cattggaaga tggcgccgca gtattgatca caggaggatt caatacgact gctgagattg
    10021 caaagctagc tgatgatctt gaaatgccga tcttacgcac ctcttatgat acatttacag
    10081 tcgcaaccat gatcaaccga gcgttaagcg accaattgat caaaaaagat atcatgcttg
    10141 tcagtgatat ctatatgcca gctgaaaaga ctcattattt gcagcagaca gatacgattt
    10201 ctgattatca gcgtttgtca gaagaaacgc agcattcgcg ttttccagtc gtcaaccgcc
    10261 atcatcgttt gatggggatt gttacggcaa aagatgtttt agggaaatcg ccaaaccaga
    10321 tcatcgatcg ggtgatgacg aaagaaccaa tcagtgtaaa gaaaacaatg agtattgcct
    10381 ctgttagcca tcaaatgatc tgggatgggc tagaagtcat gccggtcgtt tccgatgact
    10441 tgacattgga aggcttgatt acccggcaag atgtaatgaa agcgatgcag cttgtccagc
    10501 gacaaccgca gattgcagat acgatttcgg atcagatatc tggaaatatc catacgattg
    10561 atactgaccg tgaaggaaat cgtttggaaa accctaagtt caaattcgta gtagcaccac
    10621 aaatggtcaa tggcgttgga accatttctt ttggcgtact tagcgaaatc atttctgatg
    10681 tcgcacaaaa aacaatggtg atgaaccaaa aacgaaatat cttgattgaa caagtgaacc
    10741 tacattattt gcggctgatc caattggaaa gcgaattaga cattcgtcca cgtgtattgg
    10801 aaatcggcag acgttccgct aaactggata tcgaagtgtt tattgaaaac accatcgttt
    10861 ccaaagcaat cgttgtttgt caagtaatgg aacgttctta gaaagcagga gtgaaatgac
    10921 agtacagcaa gaaatagtag atacaataaa aaaatacgat aaaatcatta tccacaggca
    10981 tttgcgccct gatcctgatg cattaggatc acaagtagga ttagccgaac tattacggga
    11041 aagtttccca gaaaaagaaa tacgtcaagt aggtgaaacg attgaagggc ttcgcttttt
    11101 agcagaaatg caagaagttg aagatgtctt ctaccaagga gcgctagtca tcgtgactga
    11161 tacagctaat tcacccagaa tcagtgatca aagatatcag ttggcagaaa aactgatcaa
    11221 aatcgaccat catcccaatg atgaccctta tggagatctt gtgtgggtaa atacaaaagc
    11281 aagtagctgt agtgagatga ttgcagaatt tgctttgatg tttcctgaat ctttaaagat
    11341 gaacgttaag gctgcacggt tactttatgc aggaatcgtc ggagatacag ggcgcttttt
    11401 gtatccctcc acgacgtccc gtacattaga gattgcttcg atattgagaa attatccatt
    11461 tgatgcaagt gctttgaaca gagagattga acaaatgccg atgaaagtcg ctaaactttc
    11521 cggttatctt tatcaaaata tccaggtgga tgaaaatggt gcaggaagaa taatccttcc
    11581 gcaagaaatt cttgataaat atggaatcga tgattcagag acagcttcga tcgtttcact
    11641 tcctggagtg attgacgaag tgctggcttg ggggattttt gttcagcagc cttcagggta
    11701 ttaccgcgta cgtttacgtt ctaaggggcc gatcatcaat gaattggcta aacgccatca
    11761 tggaggaggc catccattag caagtggtgc gaatgcaaaa gatttagcag aagtagagga
    11821 aatctataaa gagatccaag atatatgcca atcgtataag agcagaaaaa cagaatgata
    11881 cttcgttcga aaacgtgcct tttgtagtaa aaatcacaaa tgtatctttt caagatcttc
    11941 tttttccgtt acaatagtgc tcactaaaga ttttaaagga gaaagaagat gacattacca
    12001 aattgcccag aatgtggctc agagtacaca tatgaagatc gaggcttgtt gatttgccca
    12061 gaatgcggga acgaatggaa caaagaagaa caagaaactg tcatagaaga cggattagtg
    12121 gtattagatg caaatggaaa ccgtctgtta gagggcgata gcgtgacagt gattaaagac
    12181 ttgaaagtaa aaggtgcgtc aggtgccatt aaacaaggaa caaaagtcaa gaacatccgt
    12241 ttagtagaag gcgatcataa tatcgattgc aaggtagaag gatttggacc gatgaaactg
    12301 aaatcggaat ttgtgaaaaa gaattaaaga atattcaagg tcttttcaca ttcttttcct
    12361 actactaatg ataaaataaa gtaaacgaaa aggagtgaaa cgaaaatgta tggttatgga
    12421 atgtatggtt ttttagatcc gacatttctt ttggtcattc ttggattagt tatttccgga
    12481 attgcgtcag cgtacgtcaa tagtactttc cgaaaatacg atcaagtgag aagcaaaaac
    12541 aatgtgactg gtacacaagc agcacaatat atattacaaa gtcaacagat aaataatgtc
    12601 ggtgttcaac aaattgccgg agatctcaca gataactaca attcaggtaa taagatgttg
    12661 agtttgtctc aagcaactgc acagtctact tcagttgctg cgataggtgt agcagctcat
    12721 gaatgcggac atgcggtaca agatgcttcg ggttatgtcc cattgaagat tcgtgcagca
    12781 cttgttccag cagctaactt tggttcgatg atttcgttcc ccttgattat ggtaggtgta
    12841 ttgcttagct ggaactctac gttaatcaat atcgggattt tcgctttttc tttagcatta
    12901 cttttccaat tggtgacatt accagtcgaa tttaacgcgt ctcggcgagc aatccaaatt
    12961 ttgagtgaag gcggactact gacggaagaa gaagtaccga tggcaagaca cgtattattt
    13021 gcagcagcac tgacttatgt tgcagcagcg ctttcgacat tcctgcagct gttgcgcttg
    13081 atcttattgt tcggcggcaa ccgaagagat taaaataaag aagttgtgaa atcagcgctt
    13141 tgatctgagc taataccgag agttagctga ttgaatacca tttatttgga ataagaggat
    13201 gtgacaagaa ttttgtcaca tcctctttgt tttgttctca taaccttttt tcatatacag
    13261 ttcatgaacc gcttttatta acttgccaaa taacactgta ttgtgcgttg tatccagata
    13321 gaaagtctcc gtttcatctg aaattttctc atgctgatct gtaatgatca aatcagcatg
    13381 ttctgaatat gcggtaattt taacagcatc tttgcgaaat aactgctgca aatggctttg
    13441 aagatgataa tttcctgtaa actgtttggt tatctgcaaa tggatgagta actgctcttt
    13501 cgtttctgtt tgtagtaagt gttggatcaa ttgactaagg tattgactga tttggtttct
    13561 ttccccattt tttgaaaaaa ttgtatcgat tttttctctt aatttctttt cctgtataaa
    13621 agaactagaa tgattggacg tggcttctgg aaagcaaagt gtagaaaaac tactgctgga
    13681 ttcacccaac agttcgaaaa aaacaactgc caacacaaga aaataaaaat aaattggtat
    13741 tttattttct aaatggttga gaggaaactg ttgagttaag taagtcatca attgaccgac
    13801 ttgtcgacaa ataaggtttt tgcttgtgga aaataaaaaa ccaatctcct gtttttgtcg
    13861 aaaagagatt tgatttggaa aaaaacaata gaaaaaataa ttaaagtagg ctctctctgt
    13921 ttctgtctct tcacaagggc gactcactga aaaagaagta aagtattctg aataatcatg
    13981 tgtatgctgc aataagtcca tcaattcagt gatttcagaa gaagtttttg gaaaatatgc
    14041 ctgttgtttg tttcgtaata tgaataaagt taacagcaag tagatatttt tttcttgttt
    14101 tgaaattttt tctatttgct catctgtact gttcattttt agtgcattta attcaagtga
    14161 ggaaaatggc caatcgttac ctccaaatgt atctgaaaga aaaaagtaaa gatagagacg
    14221 gatagataac tcatttcctt caagagtaca gcaatttttt acagatagga tccgtaaatg
    14281 gaattttatt aaggaatgat tgagctgttt tgtcagtttt tcgagatagg agggcgatat
    14341 ataaagttgt tcaagtaaat atttttttgg tacagcagtt tgtggataat tgattagtaa
    14401 catcaaatag ttaaaacgat tggattcttt taggtagcat aattttaact tagaaaaaac
    14461 agctaacttt ttagtttgat cggtttcttt ggtttggatc tctcctttat gattagaata
    14521 aataaattca tcaatcaata aaaattgctt gagtgataca tttatttttc ggatcagttc
    14581 tttgattgtc cgttttggaa tatgtaagtc attggataat tcttgtaaag aacaattatt
    14641 tttttgaatg accatttgta gaacaagtaa ctcttttttt cttgcttcaa ttagcataaa
    14701 tacctccttt ttattctgtt tttgtatata gttagacaaa aactgtgagt ggaaagtcat
    14761 ttcagtctgt gttattctca cagagtgtcg ccttcttttt tatataacgt tatttaattt
    14821 ttttgttacc ttgtttattc tattgtttat ttcctagggt attttgtcaa gatattcttg
    14881 tttttaaggc ggaaaaattg atttttaatg gatataacta aatatgtttt gataattatc
    14941 aataatattt ttagaattat ttatgttatt tatttatggg tagatgaaaa gagacggagg
    15001 taagaatgat ggggagagta acaaattata gtaaagaata tttgctgttc aaaagtatgg
    15061 tatacgtgga agaatatgga atgaagtcaa ttactgcaag agagttagca gagttctgcg
    15121 gttgttctac atacccgatt tatacacatt tcaaatcaat cagcgggtta aaagagaaga
    15181 tattagaaga aatcactgtt tattttgaaa actacttagc tgaatgcagt tccgatgatg
    15241 ttttaagcat tgtctactta ttgaaagatt ttttttctat ccatgaaagt attcgtgaaa
    15301 tcattgcaaa atctgattta gacatggatt cgctatttaa gcggccattt ttctcatatg
    15361 tcaaaggtca cacgaagatc aaagaagaaa agtcgcttga attggtatgg cttaatgcat
    15421 tgggaagttt gcgctcagat gattcttctc aagattttct tgaaatgatg aacgctgttt
    15481 gggataaaaa cgaggtgacg gatgaatact tggaaaatat cttaaaggaa cagtcacctt
    15541 aggcagcaac atgaaaaagt agatcagcca cctttatttt tcgtaaaaaa gattgtaaaa
    15601 tgtctaacga aacattggaa tgaaggagga agcgacaacg ttaccacagc aatttatcaa
    15661 aaaatatcgt cttcttttag gcgaagaagc atccgatttt ttttctgcgc ttgaacaagg
    15721 aagcgtgaaa aaaggatttc ggtggaatcc actaaaaccg gcaggattgg acatggtcca
    15781 aacttaccat agcgaagaat tacaacccgc tccctacagc aatgagggat ttcttggcac
    15841 tgtcaatgga aagtctttcc tccatcaagc tgggtatgaa tatagccaag aaccaagtgc
    15901 aatgatcgtt ggaacagctg ctgcagcaaa acccggtgaa aaagttttgg atttgtgtgc
    15961 ggctcccggt ggtaaatcaa cccaattagc tgctcaaatg aaggggaaag ggttattagt
    16021 gacgaatgag atctttccga aacgtgcgaa gattttatca gaaaatatag aacgatgggg
    16081 agtttcgaac gcaatagtga caaatcatgc acccgcagaa cttgtccctc atttttcggg
    16141 cttttttgat cggatcgtgg ttgatgctcc ttgttcagga gaaggaatgt tccgaaaaga
    16201 tccaaatgca ataaaagagt ggacagaaga atctccgcta tactgtcaaa aacgtcagca
    16261 agagattttg tcttcagcaa taaaaatgct aaaaaataaa ggacaactga tttattcgac
    16321 ttgtacgttt gcaccagaag aaaatgaaga gatcattagc tggcttgtag aaaattatcc
    16381 agtaacgatt gaggagattc ctttgactca atccgttagt tcaggacgtt ctgaatgggg
    16441 aagcgtagct ggtttggaaa aaacaatacg tatatggcct cataaagatc agggtgaagg
    16501 acattttgtt gcaaagctga cttttcatgg acaaaatcag atgcataaag aaaagaagac
    16561 acgaaaaaaa agtaaagtgc aaatgacaaa agagcaggaa aaactctgga cggagttttc
    16621 aaatgatttt cattatgaag ctactggaag acttttagtg ttcaacgacc atctttggga
    16681 agttcctgag ttagcccctt ctctcgatgg tttaaaagtc gtacgtacag gtttgcattt
    16741 aggagatttc aaaaagaatc gatttgaacc tagctatgca ttagcgcttg ctacaaaaaa
    16801 gatagagaat ataccttgct tgccgatcac tcaaaaggaa tggcaatctt acacagcagg
    16861 agaaacattt caacgtgatg ggaatcaagg atgggttttg ctagtattag ataagatacc
    16921 tgtcggattt gggaaacaag taaaaggaac agtaaagaac tttttcccta aaggattgag
    16981 atttcactga gtggattagt tcgtttattt ttttgtctat gctatgatgg agatagataa
    17041 aaaggagctg atacttatga aaacatcaac aaaagtaaca atcggattaa gcgtagcagc
    17101 cgctgccagt gtagcgacag cagtcgttgt atcgggaaaa gtaatggaaa agatccatca
    17161 tatgactact cggacgaaag taaaaaaatt cgtctatgac aaatttgatg gaaatgaaaa
    17221 attactagaa atcgtagatg gtctttcaga tagtgacttg gattctttga tgggaatgtt
    17281 agcaaaaatc aaatcaggaa aaaagaaaat ctctgtttat ggtgattcaa tcaaagattc
    17341 aaccgaagat gtaaaagacc ggctaatgca ttttgttgaa aaaatgatgt aagagaaact
    17401 agcttttgaa cactattcat tcgaaataag gggttgtgac aaaattattg tcacaacccc
    17461 tttaatctat ctttaattat gttcatgaag caataaaaga tagcaaaaca gtaaatcgtt
    17521 ggcttttttt agattgaaac cagactgttc ttgaaatttt tcgattcgat attttagagt
    17581 attacgatga agaaacagtg tttttgcagc agagctgaca ttgcctaatt cattccataa
    17641 ttcttgaatg atcacttcca tttcattttg tttgatcagt tctatgtaac ttttgatcaa
    17701 cttactatct tttacagtat cttttgtata gtaatgtaaa gccacatctt gcatagaaaa
    17761 agtacggctg tgagtataaa gattgttttg ctctgttaaa aaaatttttc tttcttcagc
    17821 aaacaaaggg acgaggtcgg tgccaggtga atggaaagaa ccaacgaata cagacgttgt
    17881 cgtatcaaaa tcagcatcta aagatagaaa aataccgttg atttcagtag catcaagata
    17941 atcacggttt atttgttcga ctaagagcgc atctgtgtct gtataaaaaa agaaatcagc
    18001 agaatagcga aataattcca aaatagtatc ttgccattct ttttttaaga attctccttt
    18061 tgattcgacg tgaagctgga tcaaacgaaa gcttttttct tgaacacaag aagcatcttt
    18121 aaaaagatag tgataccatg ggtgtttttt ttgatcgttg attacaggga ataacgcttt
    18181 caaaaggctg gtttcttgtt gagataatga atcttgtttg atccagataa aagcatcatc
    18241 aattgcaaaa gaaaggatat ccgcttctga tgctggagag ttttttttct gtgcttgtgg
    18301 gtaaagagca agtaatttat ccattttcat cttgttcacc tcttgtattt attttaccat
    18361 agaaaaaaag ttagttacag cctttttatc atatgctaaa gtaaaacaag aaaaaacaaa
    18421 ggcagggaag ggtaattggt aaatacaaat cttgatgcag tagaaaaaga aaaatggatg
    18481 cgccttgcat tggcagaagc aaagaaagca gaaatgcttc atgaagttcc gattggagca
    18541 gtggttgtat tggatggaaa agtgattgga agaggatata accttagaga aaccacgcaa
    18601 gatgctacta cacatgcaga aatgcttgca atcaaggaag cctgtgaaaa agtgggaagc
    18661 tggcgcttgg aagatgctgc actttttgtt accttagagc cttgtcctat gtgcagcggc
    18721 gcgatgattt tgtctcgtgt agcagaagtt tatttcggcg cgtatgatcc aaaaggcgga
    18781 acagccggta ccttgatgaa tcttttggag gacgagcggt ttaaccacca agcatatgta
    18841 gaaggtggca ttttagaaga cgaatgtggg atgattttga ctgacttttt ccgaaagctc
    18901 cgccagcgaa aaaagaaatt aaaaaaagac tggtcaacga atgaaaaata aggtatacta
    18961 ttctttgccg aaaggctagg acaatggtgg gcttgtgaag cgtgtcaggt ctggaaggaa
    19021 gcagcactaa gcaggttccg ccatgtgtct gattataatg aaacgacaac agactttcgg
    19081 gtctgttttt tttattttta tagtactgta aaaatgaatg ttcctgattt tttagccaga
    19141 ctgatttatc gaatattgta cttatacaat ttgcttcaag gcaggaaaaa ctctgaaata
    19201 gagcttgttt caatggaaga aaaagctgcc tatggtatga taaagataaa gagaggcgag
    19261 agggtacatg gaaaaaatag tgattttaca tacgaatgat ctgcattctc atttagaaaa
    19321 ttggccaagg atcagaaggt ttttggatca acgtaaacga gaaaacgaaa agaaagaaaa
    19381 aacgacaacg attgcagtag atctaggtga ttttgtggat cgttggcatc cattgtcaga
    19441 agcaacgaat ggacaggaaa atatcttgct gatgaatgaa gttggttatg atgcagcgac
    19501 gataggaaac aatgaaggcg taggaaattc caaagaagag ttgaatcatt tatacgatca
    19561 tgctgagttt gatatcatcc tggataactt attcgataaa aatacgctcc agccaccggc
    19621 atggacgaaa ccatataaaa tcattacaac gaaacaccag acgaaaatcg gactaattgc
    19681 atttactgct ccatttccgc ttacttataa tccgaatggc tgggacatac ggaatcctta
    19741 tgatattttg ccagaattag tcgaagattt acgttcacaa gtggatgttt tagttttgat
    19801 gagtcatctc gggattcagg atgatttcca aattgcaaaa gaaataccag caattgatgt
    19861 tattttagga tcgcacaccc atcatttatt cagagaaggt cacgtaatca atgatgtcca
    19921 aatagcagcc gctggaaagt acgggcagta tgtcggtgaa gtccatttaa ccatcgatga
    19981 agagaaaaaa atccttaagc attcagccaa agccatccct accgaaacaa tgacagcttt
    20041 tacagaagat gaacaagaaa taaatagttg tctagaacgt gggcatgaat tattaaaaga
    20101 aaaagaagta gcagatttgc cattttctct gagtctagat atcttcaatg agcattcgtt
    20161 tatccaagta gcctttgagg cggtgaaaga acgaggaaag acggaagcag caatattaaa
    20221 cagtggtctg tttttaactg aaattccaaa agggcgggtc aatcaggatc agcttcacac
    20281 tgcgttgccg catccgatgc acttgttaaa tgtcacattg ggtggaaatg atctgatccg
    20341 cttagtttta gaaatagaaa aaaatcgtaa ctttttacgt aactatccta tgaagggaat
    20401 gggatttcgc ggtaagattt ttgggcagat ggtctataat ggaatcacat atgattctat
    20461 taaccatcaa gtcttttgga agaacaagcc aatcgatctg aataaaaatt atacttttac
    20521 taccgtagat catttgatgt ttgttccatt ttttccaacg attgagattg ctggaaaaaa
    20581 tgaatttttg ttccctgaat ttatccgaag tgtggtagga gattacttga aagctcacta
    20641 cccaatcaaa taaaaacaag gtataataaa aaagataggt ggtgaacgca tgtctgcaaa
    20701 acaaaatgaa cagcagaacg ttgagcataa aacagaaatt gctaagaaaa aatcatcagc
    20761 tgaacaggaa acaacagtca ccgaagaact gacagctgct ttggaagaaa tcgttgagga
    20821 gcctaaagca gaaaaagtca aaggcgagct agtgacactg ttagatgaca gtaatttttt
    20881 gataggtgaa agacattatc ggcttgtgtc cgattatcgt gaaggattta atgcagaaaa
    20941 gcttggagaa cgttacagtg atgtactagc ccgatatgat tatatcgtag gagattgggg
    21001 ttatgaacaa ctacgcctaa aaggattttt ccaagcggat aatcgacggg cgcatccaga
    21061 tcagcgaatc gattccttgg aagactatct ttacgaatat tgcaattttg gttgtgcgta
    21121 ttttgtcatc gagagaatcg gcggtaaaaa agaaaagaca actcagcgcc gaaaaaagaa
    21181 aaaaaaccat aatcgtgcgt atatcgatga gaaaaaagga ccagtcgcat ctaatcgcaa
    21241 aaaaccggtt attaaaaatc gaaaaacaga gtcagcaaaa acctctgaaa aagtaaaaaa
    21301 acaagaacaa cctaaacaag tagaaaaaac aaaaacagca tttacgatca gaaaaaggga
    21361 agagtagtgg atgaatggac tataaaggat atttaattga tttagacgga acgatttatc
    21421 gtgggacaca acccataccg gccggtaaac gatttgtgga agaattgcaa aaaagaaaat
    21481 tacctttctt gtttgttacc aataacacga ctaagtcacc agaaacagta gctaatcgtc
    21541 tagcagatga gtttgacatt catgtagctc cagagacagt ctacacagct actttggcaa
    21601 caatcgattt tatgaaagca gatggaaaag ggaaaaaagt ctatgttatc ggagaagcag
    21661 gattgattga cttgatttta gctgccggat ttacatggga agaagaggct cctgactatg
    21721 tagtggtagg cttagataat tatctgacct atgaaaaagt agttaaagca acacttgcta
    21781 ttcaaaaagg tgctactttc attggaacga acccagataa gaatatacct actgaacgcg
    21841 gccttcttcc tggagcaggg tcagtcatct cttttgtaga gacagcaacc caaacgccgc
    21901 cgatctacat cggaaaacca gaagccatca ttatggataa agccgttgaa gtattagggc
    21961 tgcaaaaaga agaagtaatc atggttggag ataactatga aacagatatc caagctggga
    22021 tacgcaataa tatagatact ttgctcgttt tatcaggttt tacaaaagaa gaagatgtac
    22081 ctgggttgcc tatcccagct acctatgtga aacaatcact ggatgaatgg agcttctaat
    22141 atgaaaaatt cgagatggca gtggatggaa tatgctggat tgttcagcct atttctgaca
    22201 ctgatcagtc tggcagttgg tgtgacgatc aactttcgac cactatacgt atttgatatc
    22261 ggacatttgc aaattttgga ttatacttct ttagatcaag agacgttact gaaaaatttt
    22321 gatcacctaa tgaattatct caataatccc ttcaaaacca tcctcagctt gccagatttc
    22381 ccagtttctg ctagcggagc ccatcacttt tatgaagtga aaattttgtt tttagtggat
    22441 tatgctgtgt ttttcatcac tttgatcccg agtattttgt ttatcaaata tttgcaaaag
    22501 aatgatcggc tttggcggtt gattcgtccg tttcaaatcg gcatgttact gccagttgtt
    22561 ttcggttttt tcatgatgat aggatttgat cgctttttta tcctttttca tgaaacgttt
    22621 ttcaacaacg atgactggtt attcgatccc gttactgatc caatcatcaa tgtacttcca
    22681 gaagaatttt tcatgcatag ctttatctta ttttttgtat ta
//
LOCUS       DADVXV010000046        22688 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.047, whole genome shotgun sequence.
ACCESSION   DADVXV010000046 DADVXV010000000
VERSION     DADVXV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.047"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            69..3347
                     /locus_tag="KB969_001654"
     CDS             69..3347
                     /locus_tag="KB969_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBB6869640.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3888..5795)
                     /locus_tag="KB969_001655"
     CDS             complement(3888..5795)
                     /locus_tag="KB969_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBB6869641.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5925..6800
                     /locus_tag="KB969_001656"
     CDS             5925..6800
                     /locus_tag="KB969_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBB6869642.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6880..7854
                     /locus_tag="KB969_001657"
     CDS             6880..7854
                     /locus_tag="KB969_001657"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBB6869643.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8034..9179
                     /locus_tag="KB969_001658"
     CDS             8034..9179
                     /locus_tag="KB969_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6869644.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9316..9660
                     /locus_tag="KB969_001659"
     CDS             9316..9660
                     /locus_tag="KB969_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBB6869645.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9931..11217
                     /gene="efmA"
                     /locus_tag="KB969_001660"
     CDS             9931..11217
                     /gene="efmA"
                     /locus_tag="KB969_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBB6869646.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11355..11954)
                     /locus_tag="KB969_001661"
     CDS             complement(11355..11954)
                     /locus_tag="KB969_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBB6869647.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12358..13479
                     /gene="mnmA"
                     /locus_tag="KB969_001662"
     CDS             12358..13479
                     /gene="mnmA"
                     /locus_tag="KB969_001662"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBB6869648.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            13725..15146
                     /gene="arcD"
                     /locus_tag="KB969_001663"
     CDS             13725..15146
                     /gene="arcD"
                     /locus_tag="KB969_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBB6869649.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15160..16278
                     /locus_tag="KB969_001664"
     CDS             15160..16278
                     /locus_tag="KB969_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBB6869650.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16338..17630)
                     /locus_tag="KB969_001665"
     CDS             complement(16338..17630)
                     /locus_tag="KB969_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6869651.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            17762..18340
                     /locus_tag="KB969_001666"
     CDS             17762..18340
                     /locus_tag="KB969_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6869652.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            18469..18846
                     /locus_tag="KB969_001667"
     CDS             18469..18846
                     /locus_tag="KB969_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBB6869653.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18779..20851
                     /locus_tag="KB969_001668"
     CDS             18779..20851
                     /locus_tag="KB969_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6869654.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(21062..22009)
                     /locus_tag="KB969_001669"
     CDS             complement(21062..22009)
                     /locus_tag="KB969_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6869655.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            22255..>22688
                     /locus_tag="KB969_001670"
     CDS             22255..>22688
                     /locus_tag="KB969_001670"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBB6869656.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQ"
BASE COUNT         7348 a         4142 c         4814 g         6384 t
ORIGIN      
        1 tgacagtaaa aataaattag gtaatacttt aagtaaacgc tttctaattt gttacgggag
       61 gaatacactt gttaaaaaaa cgtataaaat acagtgcgct aatgatgaat ctccttatgc
      121 tcagtacccc ggttttaatt tctgtcgttg aagttgctgc taacgaacaa cagtctgtga
      181 acgaagaaaa tgcacacgtg aacattgaag ggatgtcaac aatggaggaa ataccaagaa
      241 ctagtgaaga tatggatacg gaagaaggaa atgatcctat gatgaaagaa tcagaaaatg
      301 aaaagacaaa aaagcaatct gaagaagcaa atgaagagtg gaaaggggtt gttttcggag
      361 aaagcacaag tgctagtagg tatgccattg aaccattaga agacggcgtg cggctctctt
      421 ccacgaataa cggcggaaaa ttccagtcaa gcggatcaga tggaatgacc tattattatc
      481 aagcaatccc taaagacatc aactttagga tgcgggcgac gatcgaaata gaatcttgga
      541 cctatacgaa tgcccaagaa ggatttgctt taatggtaag agacgcagta ccaaaaaatc
      601 atttgtttgg gcaggcattt tattcaaatt catttgccat actaggcagt cggatcgaat
      661 atgtctggga ctcggataga caagaagtgg tcaacacgag cggcagcaaa tatacgatgc
      721 gacttggatt ggggacacgg gcaatcacag gaatatcatc tgaagatccg caagctgcgc
      781 cagctcctgg gagtgtctca gtggaaacaa cacctttaga gacttcagca gggttcttgg
      841 aaaaagaaac aggttcttat aatatattcg gaaacggtca tgggaatctg tttccggcca
      901 cgaactcgat tactaaactg gacgtagaga tgaaaaaaac gaatactggt ttagaggcat
      961 attattacga tcctgaaaca ggagaagaaa tggcttctga catcatgtat gactgggaaa
     1021 aattatacgc ttcagatgaa tcggttattt atgcaggatt tgctgcagca aggaatatga
     1081 cgatcaaggt agaaggaatc gaagttgctt actcagatcc tgcgacagat cctcctgggc
     1141 aagaaagacc tactcgcttg attgatccga tttacactgt gacctctagt aatcattcag
     1201 gaaaccaaga tcatactatg tcctttagag caaatgctga cggattattg acaattaaaa
     1261 ataaagcaac aggagaggtg cttaagaacg caaaaaactt ggctatcact gcgaatcggg
     1321 aatttgatta tcagacaaaa ctgatggaag gaacgaacga atttactttc agttttacgc
     1381 cagataaaaa ctatccgcca gaagaatacg tagagatgac tagttatgaa acaaaagaga
     1441 ttcttcatac agtggactac cgtaaaccta aatattcgac agtttatgta acaccagaag
     1501 ggtcagatgc aggaaacgga agcagacaaa atccattatc tctgacacaa gcattgagat
     1561 acgcatatgc tgggcagaca atcgtcatgg cgcctggaac ttattccttc gaaagaggat
     1621 tgacgattcc aaaaggcgtt aacgggacaa gagaaaaccc gattcagttg attgcagaga
     1681 aaaatccaga aaacaagcgt cctgtacttg attttaaagg aactggaaat gggatgacac
     1741 tgttcagtca ctactggggt ttacgagggt ttgacattac aaatagtgca gctatgcaaa
     1801 aaggattaca gatttctgga aatcataatt tgatcgaaga gattcatgct tatcggaatg
     1861 gaaatacagg aatccaaatc agcggtagct caaatgatcc tttcgaagca tggcccgcgc
     1921 ataacttagt caagaactgt acatcttttg aaaatgccga tccaggattt gaagatgccg
     1981 atggatttgc ggccaaactg acaataggag aaggaaatgt atttgacggt tgtatcgcgt
     2041 atcataatgc agatgacggt tgggaccttt ttgctaaaaa tgaaacaggt tcgatcggaa
     2101 aagtaatcat caaaaactca gttgcttatc gaaacggctg ggtaccagga attgagggag
     2161 aaggtaacgg taatggattc aaaatgggcg gttcttcttt aacgggccct catgaattga
     2221 tcaatagttt gtctttcgaa aatcttgcga aaggaatcga ttccaatagc ggaacagata
     2281 ttatcgtcaa tagcagtaca agttttaata acggttcata taatgtggct ctttatacct
     2341 cttcagcagg aaacacagac taccatgctt ctggtatctt atctttccga acagagaatc
     2401 ttgagatgag agagcagatc cgcccattga atcaaaacga agatcaaatc taccactcgt
     2461 tgaactacta ttggaatgaa cgagagaaac aatcagaaaa tactcttgga cataccatat
     2521 caaaagattg gatcgagtct ctaaatacat gttcgaaaga aggtcagcag cctgttacgc
     2581 gctatgaaaa tggaagtatc catgttcatg gactgatgca gattaaaccg gggaatcgtc
     2641 aaacagaaaa ggaaagagtg gatggtcttc cattatctgt aggtgctatt tttgacggag
     2701 aaacctcacc gtcttcggaa tatccagagt atgcaatcgt acaagaacca aatcagacaa
     2761 aaccaaatga acaaaataat ccgattatta tacaagaagc aaatggtgtg gcggagaatg
     2821 cagaaggaaa tatcattgaa ctgaagcctt ttacagtttt tgtgtcaact ttcacaccaa
     2881 atcaaggaac gcctgtcttt gaagatatgc gttatttccc agaaaagatc caaatcgttg
     2941 aaacacagtc aagtgctcaa ttttctaatc ataccgctat tttttcagca ccttcaaaag
     3001 gagaatatac gctagaagtc acttatcgtt cggaaatatt tgatggggaa aaatggtctg
     3061 ctcatacaga atctgttacc cagcaaaaag cgatcactgt gcgagaaact gccgatgtgc
     3121 ccccgggaaa tgacaaacca gaaagagaaa atccaggaaa tgaatcacca aatggaaaac
     3181 caaatggaaa accttctcat ccggatagga cagcaaaaga aagtgaaaaa aatggcactc
     3241 aaggactccc aaaaacggga gaatttaata acccgttgct agcattagct ggaggaattt
     3301 tgttaatcgg tgtagttgtt tatgtcatga aacagcgaaa aaaataagtg gaatttctcc
     3361 ttttatgatg taaaacaatt gactgaggaa agtaaaaata gaaggaaatg agaccaatag
     3421 atgtctcact tccttctatc tttttataga tgaggttctc cttgctgctt ttgattggct
     3481 gttcttatta cttgatgcag gacagctttt tcacaatctc tccactaaac ggtgttcaat
     3541 cagctgaccc tcggtattag ctcaacaaac ggcaaaatat gaggaactat ttttccgttt
     3601 ttttctctaa tactcaggtc aggacgctga tttcacaacc tctcgataaa cggtgttcaa
     3661 aagccagttt ctcggtagta agtcaaattt atgcaaaaat gtggaaagcc attttcacaa
     3721 aatttttctt actacttgaa actaagcagc tttttcacaa cctctaatac atggtattcc
     3781 agaagtaact tcttcgaaaa ataagccgaa atgtcacaaa aatttgagaa gcgattttcc
     3841 caaattcctt cttatttctt gaagctgacc acttctggca caacctctta ccagattcgc
     3901 actctttttt ctggcgctag atacatagcg tcttgttccg tgataccaaa tgtttcatag
     3961 aattcgtcaa ggttttttgg ttgcacgttt gctcggagtt tagcaggggc atggacatcg
     4021 atttgcagta aaagttgttg gtattctttt tttgcttttg tacgccaaat cgttgcccaa
     4081 ttgacaaaga attcctcgat agaaagatct gattccgttt ttgctgcttc caatgcacag
     4141 cttagaccgc ctgcatcagc aatattttcc gaaacggtta attttccgtt tacttttccg
     4201 tcagcaaaag gcagaccatc gaattcttcg atcattgctt gtgctttgtt ttgaaattgt
     4261 gtaagatctt cttctgtcca ccagttgttc aagttgccat attcgtcaaa taaagcgccg
     4321 ttattatcaa atgcatggga aatctcatga gcgataacag ctccgattcc accataatta
     4381 gcagagcttg attgttctag actgtaaaat ggtgcttgaa ggatcgctgc cggaaagacg
     4441 atcacattcc gaaatggatg ataataagca ttgaccgtgt cagcactcat ttcccattct
     4501 gaacgatcca ctggtttgtt ccatttgctg aaacgatctt ttaatgtgag tttgctgaaa
     4561 acaagagtat ttgaaagcaa agtaccaccc tgatctgcag gtactgtttt gaactggtcg
     4621 aataatgctg ggatcttatc ggggtagcct acttggatac ctaagttatt taattttatg
     4681 acggcttttt cttttgttgc atccccaagc cagtcatttt cttctagacg ttttttataa
     4741 acggcgatca tttttttcac catttgttct acgtcttttt tagcagcttc gccaaaatat
     4801 ttttttccgt agtaatcgcc aactacttga tcgaattgtc cagaggcaag gtaatacgct
     4861 gcttttttct gaggcattgc ttcgtctgtt ccagacaata cgcgagaata gattccgctg
     4921 acttggcgga attcttctga tagataacca ctaagagaac gtactgtttt aatgatcatc
     4981 cagcttttga ataacggaaa atgagcttct gtcaggatgt cattcaaatg atcgaagtac
     5041 actggatcag ttacgatcac tttatctgga gttgtcccaa tcaaacccgt gacaagtttt
     5101 ttcaagtcca gtttatctgt gtatttaata aatgtatcaa aagattgcgg attatacatt
     5161 ttgctgtaat ctgcgttttc ttctgcactt tttacatgag gagcaatcaa tttatcaaat
     5221 tgcactgctt gttccgtgat tgcttctgcc tgactttttt ctttgccggc aagctctaat
     5281 aactgaacag ccatatcaaa gaaaacgcct attagttgtg caccgttggg atggtctgat
     5341 gcataatacg tcttatctgg aaggaataaa gaaggcggat aagcaaagaa ggcgttcgtt
     5401 tgcgcattct tcatatctgc atctacatcc agattaaatg gcaatggtaa tgtatccaac
     5461 agccattctg gaaattgctt attcaattcg tcgaaagact gcaatgattc aactttttcg
     5521 attataggtt gaagcggttg agcatgcaac tcatttcttc ggtcataatc gtttgccagt
     5581 tgataatatg caaggaaatg tttcattttt tctgaagaca ctttttctgg atgggcaagc
     5641 agatcgtctg tttctcccat caaaagttgg tcgatcccgt caactaaatc ttggaaaccg
     5701 cctgtagctg gtttatctgc agggattttt gctgtttttt gccattcttc attgactgct
     5761 tcatagaaat cttgtttcaa tcgttctttg ttcattcatc gatcgctcct tttttgtttc
     5821 gtgtgcccat tatcttacaa aatgaaggaa ttaacaaata gaacataaaa aattgaaaat
     5881 tcgaacaatc aaactgattt gtttttttca atccttcact tataatgaaa aaaaggaggc
     5941 gatcccaact gaatcaagta gtggataaac ctttatattt caaagtagat aaaaaaatta
     6001 aaaaattagc cagcactcag cagctgcagt caagaaaaag taaattgctt tttttagctc
     6061 tggtttttga agatcaaagt tatgtgatta tcgatcaatc aggacatccg gtagaatatt
     6121 ctccagcaaa atatacttat caagagggtc tttcttgtaa aaaatggaag ctgatcaatg
     6181 aagagccaat cgagttatct agatggatca acagaaaaga agatattccc gttttgatcg
     6241 aagaaaaaag gtcaggaaag gaactcgcaa attgctgggt gggattgcca gaagaacgtt
     6301 ttttgaggta taagaaatgg gctaccccct caggctatct ttgtggtact tacgcggcag
     6361 cagttctcct tgcctattat caagactatc gtaaggggtg gatgcttcca aatgagattc
     6421 gcaagaaaaa tacggctgat tcgttggttt tgacgaaggc attgcgtagc cagatccaac
     6481 cactaggact tcctacgatt ccttttcagg ttagtacagg gatttctagt tttttaaaga
     6541 agaatggcaa tcatgagcgt gcacgagcaa ctcttctagg ttcatggcag cgagctacaa
     6601 aacgtatacg tgaaggcaaa cctgtgatga ttggtatttt gaaagtactt ggcagtacat
     6661 atggcaatca ttgggtgaca gcgtacgctt attttgaaac tgaaacagga gaacgttatt
     6721 acaaagtaca cgacaactgg ggcgattatc ataaagtcat tcctgccagt tggagtaacg
     6781 gaacagtttc acttccttaa gaatttgctg aaattaacag aaaatcttgg aaaaatatgt
     6841 taaactatcg aagaatagag aagttttggg gaggactaca tgagtaataa gtatcaggat
     6901 gacacgttga agatttttag tttgaatggc aaccgtccat tagctgaaaa aatcgcgaaa
     6961 gtgttcggaa cagaattagg taaaagcgtc gtgaagcaat ttagtgatgg cgagatttcc
     7021 atcaatatcg aagaaagtat tcgaggggat catgtgtata tcgttcaatc aacgaatgca
     7081 cctgtcaatg attactatat ggaactactg atcatgatcg atgcaatgaa gcgagcaagt
     7141 gcgaaaacga tcaatgtcgt attgccttac tatgggtatg ctaggcaaga ccgcacggcg
     7201 aaacctcatg aaccgatcac tgcgaaattg atcgctaact tgatcgaaga agcaggggca
     7261 actcgagtac tgactttaga tctgcacacg gttcaagtac aaggattctt tgatattcct
     7321 gtagataatt tatttacgat gccgttgttt gctcattatt accgtcaatt aggtctgacg
     7381 ggagatgaca tcgtagttgt ttcgccaaaa aacagcggtg ttcagcgtgc acgtagtctt
     7441 tcagaatatt tgaacagcac attagccatc gtagatcatg cagatgatgc ttcaactgag
     7501 ggtggttatg tgatcggtga tgttcaagga aagacatgta tcatggtaga tgatatcttg
     7561 aacacaggag caacgcttgc acgagcagca aatgtattaa aagaaaacgg cgcaaaagaa
     7621 gtatatgcct gtgcgtcaca tggattattg tccgatcatg cgaaaagtat tttagacaat
     7681 gcaccaatca aagatatttg tatcactgat tctgttttca cagaagaaaa tcgtcatcca
     7741 gaaaacttaa caatcgttac atgttcagaa ttaatgggtg aagcggtcaa acgcatccat
     7801 gaaaatacac cgatgagtcc gttattccgt ctggaagaaa aagaattcga ataaacaaaa
     7861 aaaagaggga aagaagttgt gacagaagtg agcagcttca aggagctgcg acaagacttt
     7921 tgtcacagct ccttttttct atgcccatga aacgtcctct agacaaaaat gagctcttct
     7981 ttggtttgtt cgctatttta tgctagaatg tgcctagcaa taatttggaa gggatgaatg
     8041 aagtgaaaac tatttatctg gatcatgcgg caactacccc catgcatcca caagtaattg
     8101 aagcgatgac ggcaatcatg caagacacgt ttggaaatcc ttcaagcata catggatttg
     8161 gtcgccacgc gcatgaaaaa ttggaaacag caagacaaat cattgcagac agtctgcaag
     8221 caaaacctca cgagatcatc tttaacagtg ggggaacaga aggggataat acagctatct
     8281 tagaaacagc gttctcgcgt caaaaagaag gcagacatct aatcactaca gctatcgaac
     8341 atcctgctgt tcttaatacc atgaaatatt tagagacaaa ggggtttgac gttacatatc
     8401 tgcctgtaga tgaaaaaggg aatctgtcga tcgaagaggt caaaaaagcg ttacgagaag
     8461 atacgatctt ggtctctgtg atgtacggga acaatgaaat cggaaatttg atgccaatca
     8521 aagaaatcgg tgaactttta gcggatcatc cagcttattt ccatacagat gcggtacaag
     8581 cgtacggaaa ccaaacgatc catccagaag aattaggaat cgatttatta agtatctctg
     8641 ctcataaaat caatgggcca aaaggcgtcg gtttcttata taaacgagac ggagtaaata
     8701 tccctgcatt gcttttaggc ggggagcagg aagaaaagcg gcgtgcaggt acagaaaatt
     8761 tagcagggat ctggggtatg gcaaaagcag ttgaactgct gtcacctgaa gaacgtgaag
     8821 cacgtaacaa caaatataaa ggattccagc aattgattct tgatacatta gaagcaaacg
     8881 aaatccctta tcaagtaaat ggtgatttaa cgaataaact ccctcatgtg ttgaatcttc
     8941 gcttaattgg cgaagcaaat gatttgctac tgatgaagct tgatcttaat ggggtcgcta
     9001 tttctactgg ttcagcttgt acagcaggaa atatcgagcc ttcacacgta ttagaagcaa
     9061 tgtatggaga agatacaccg atactaaaag aatccatccg tatcagcttt ggtttgggaa
     9121 ataccgaaga cgacatccag tatttccttg atcaattagt tcgtgctgtc aaaaaataac
     9181 tagtgaagtc attcttatat gaacagatgt ctgagagaac gccttcattt tttagggaac
     9241 ttaactgaaa aacctagtaa aaatcaggat aaacttttat aataaagaga aactaatttt
     9301 atcgaggtga aaatcatggc atttgaaaca acagcaacgg tactgggcgc accaattagc
     9361 tatcgtttgc atcctgatgc aaaaagatat acattgcgcg ataatggatt tacagaaaca
     9421 aacggaggca attatcaatt gatccgacca ttagatgcca cgccgcaaag caaagaagga
     9481 ttcaaattaa aaatcactgt atcaaaagat attcaaacat tgaaaatgtc gatcactaca
     9541 gcaaatggat tgaaagcagt caatattttc aaagatccaa aacagaaaat gagccaagat
     9601 aaattttatt ttctgatgga tgggatgatt agccgtgggt tattcgaaaa agtcgaatga
     9661 tctgtggata taaaaagaca actagttttg aaacggccta ttgttagatg actaactttg
     9721 taaggacgac gcaaattagt tgtctttttt atttttaaat ttaacacatg ttgttatttt
     9781 taatattttg ctgatttatt gtttctaagt aaagaaattt aaattgaaac gattgttatt
     9841 tagggaaaaa ggtatttttt gaaaaaagaa tcccgtataa tgattgttgt gcaaacgcta
     9901 tacaaaatga aaaagaaaag agggatgttt atggaaaatg aacagtcggt cgttttaacg
     9961 aattggaaga gaaattattt gttcttttta tcgggacagt ttttgtcagg aatcactagt
    10021 atggtcgtcc aatatgcgat catctggtat ttgacaagag aaaccggttc ggcgacaatt
    10081 ttgagttttg ctactttact aggaatgatt cccatggttt tactaagccc atttgtagga
    10141 ccgctagtgg atcgctggga taaaaaagct cttttgattg tcacggatat tattgtagcg
    10201 attttcgcgc ttattttagc agtagtcgga acgatttcag aatccttccc gatttggcta
    10261 gtttttgtgt ctttgtttat gcgttcggtc gcacaaacat tccaaatgcc aacgatccag
    10321 tcgattatgc cgacaatcgt tccatcttct cacataacaa ggacgaatgg acagttagga
    10381 atggtccaat cagcgaattt catcattgcg ccagctctag gtgcggcttt gttttcagtc
    10441 gttcctgtca attaccttat tttattagat gtattggggg cagtttttgg tgtcggctta
    10501 ttgatttttg tgaagatccc aaaagtttct cctgaaatat tggaagttcc gcttactatt
    10561 tttaaagatg caaaatttgg gctgcagcaa ttgatggata ataaagggtt atggtacata
    10621 acgatcaatg gtgcatttgt gatgctgttg ttcatgccag caatcagtct gtatccattg
    10681 atgacgctag attactttgg tggttccgtt ggacaggcgg gagcagtgga agtagtctac
    10741 gcagtcggaa tgctcttagg cggtgcactg atcagtttta taggaacatg gaaagaccga
    10801 atgaaaccta ttattatagc ctacatcatt atgggcctga cgatcggtgc aagcggattg
    10861 gttccaaacg atagtcaagg gttcttgtac tttcttatct tgaatgcagg agcaggttgt
    10921 gcaacgccat atttcaatac actgctgatg gcaatgatcc agcagagtta tgaatcgaat
    10981 gttttaggtc gtgtcttagg gaacttcaac tctttgatga acctggcagg tccaattgga
    11041 ttattatttg caggaccatt agctgatcgt ttaggggtag aaaaaatgtt cttgttttcc
    11101 ggaatcggga ttttattatg cggaatcgtt ttatttttaa cgtcagctgc ccgaaattat
    11161 gataaagaat tacagaaaaa actggtaaaa gaacaccatg agcaaaaaga cgaatagtat
    11221 ggaatggagt tgtgacagaa gtcttgttac aactccattt ctgatcctaa tgttcctgtg
    11281 gcaataagcc tactcaaatg aaaaatatga gtaattatct ttatttgttt aatacttgat
    11341 atagggcagt tttttcacga cctatcgtac ttcctctttg cttcatagat ttctttgatt
    11401 tgttgctcag ataacggagt gccaaatggt agtttttcct ttaagagttc tctttccggt
    11461 gcgtctacgc ctacattgac atcgttctcg ataggtacgc tgtaatgatg gatatgtcca
    11521 tgaagattgc ggatagtgtc gttaggcccg agcaacatcg gataatgagt caagtaatat
    11581 tgttgatggt cgaatttaac gatggcacct acatcataaa aataaaattt gggacttccg
    11641 tcagtaagcc taggatcatt tttttctaaa taacggaaaa aagcgcgact gtcatggttc
    11701 cctttgatca agtggattgt tccttgcagt tgagtgacca gttccaaaat ttctgcattt
    11761 gctttttcat attgcggatg catagcaagg tcgcctagat gataaacatg gtcggtttct
    11821 tttattactg cattccagct agtgatcaac tgttggttca tttcatccac atttgcaaag
    11881 agccgcggag caaagtcgtt ttttcctaat aagcgttcat ggaaaaagtg catatcactg
    11941 ataaagtaat tcatgtatct tttgcctccc ttttttctta gagtaaacaa aatcacttat
    12001 ctgagcaact cataacatct aaaaagaaaa ggttgtaaat gagacgtgca gctttaagcg
    12061 ataagaagca attttgaaaa atagtttttc acaatttata aaattattcc ttattgccga
    12121 aaggctggcc ctttttatga gtatgccaat tttttatatc gaatgctcaa aagatgagtg
    12181 attttttggt tgactatcat gtttgtgtac tgaataggtc cagtagaaca gtatttttac
    12241 gacttgataa ttaagggatg aaattttcag aaatatgacg tataatgtaa aatactgaaa
    12301 agttgcgacc ttcaactcgt agatgtttca gaatctaatt gaaatgatgg tgatatcatg
    12361 acagacaaca gcaaaacacg cgttgtcgta gggatgagcg gcggtgtcga ctcatctgta
    12421 acagcacttt tgttaaagga acaaggatac gacgtgatcg gaatattcat gaaaaattgg
    12481 gatgacacgg acgaaaacgg tgtatgcacg gccacggaag attataagga tgtagcgaaa
    12541 gtagctgctc aaatcgggat tccttattac tctgtgaatt ttgaaaaaga atattgggat
    12601 cgtgtatttg aatatttcct agccgaatac cgcgcaggac gtacacctaa cccagacgtg
    12661 atgtgcaaca aagaaatcaa attcaaagca ttcttggatt atgcaatgga tcttggcgcc
    12721 gattatgtag ctactggaca ttatgcgcaa gtcactcgcg atgaaaacgg cgtggtccac
    12781 atgcttcgtg gagtagacaa taataaagat caaacttact tccttagcca attatcacaa
    12841 gaacagcttt caaaaacgat gttccctcta ggcggcatgg aaaaatcaga agtacgggca
    12901 attgctgaac gcgcaggcct tgcgactgct aagaaaaaag attcaacggg aatctgcttt
    12961 attggtgaaa agaacttcaa acaatttttg agcaactatc tgccagcaaa aaaaggaaat
    13021 atggtcactc ttgatggtga agtcaaagga caacatgctg gcttgatgta ttatacgatt
    13081 ggtcaacgtc aaggactagg gatcggtggc ggaggagatt cgcaagaacc ctggtttgtt
    13141 gtaggaaaag atctagcgac aaacacatta tatgtggggc aagggttcca tcatcctgca
    13201 ttgtatgcca caagcttgga tgcaagtgaa atccacttta cgacgaatga accaatgcca
    13261 aaagaattca agtgtacagc gaaattccgt tatcgtcagc aagacgttcc tgtgacagtt
    13321 cgcttattgg atgataatcg tgcagaagtc gtattcgacg aacctgtacg tgcaatcact
    13381 cctggacaag cagttgtatt ttatgatgga atggaatgtc tgggtggtgg tttgatcgac
    13441 cacgcatatc aagaaacaaa agttttacaa tacgtttaag cgatattaaa tgaatcaaaa
    13501 cagctatggc taacaaaaga aacacctttt cttttggata gcatagctgt ttttttgcaa
    13561 taaaattaat ttttattcat tttatacttg aaatacttgt gtaaaaagtt cataatatcc
    13621 aataatatga ataaagttgc tttttgttaa gcaagagcag ttgcaaaata gaagggaatc
    13681 ttttgcaagt gatttgttca attttataag tgagggtgat ggaaatggaa aagaaatcga
    13741 cgggtattag caaatgggga ctggttgctc tggttgtcag ttcgtcaatc ggaagcggtg
    13801 tgtttgggat cacaagtgat ctggctagtt ctgcagctcc agggccagcg atcctttcat
    13861 ggataatcgt tgggattggt attttagctt tggtattatc gctgaatcat ttaggagaaa
    13921 agcgtccaga tctagatggt ggtattttcg gttacgcgga agcttcattt ggtaaattag
    13981 gtggcttcat cagtggttgg ggttactggt tgtctgcgtg gctgggaaat gttgcttttg
    14041 caacgatgct gatgagcgcc atgggagaat ttttcccgat attcaaaggt ggacaaaatg
    14101 ttccttctat tttatttgca agtattttta tttggggtct gactttatta gtaaacaatg
    14161 gagttgaagg agcgagcgtc atcaatacaa tcgtgacgat ctgtaaatta gtgccattat
    14221 tcctattttt aatatttgta tttatcgcat ttaaagtgaa tatattcact gctgattttt
    14281 ggggtaacgt atctgataat ctagtgaatg gaacagggca gcaaggaacg atctggttgc
    14341 agattaaagg ttgtttgatg gttatgatgt gggtctttgt agggatcgaa ggcgcaagtg
    14401 ttttagccaa ccgcgcgaag aaacgttcag aagcccagca agcatcgatc attggtctgc
    14461 tttgtttatt gtttatctat atccttgctt cgatcttgcc atacggcgtc ttatctcaag
    14521 aagagttagc aactatttca caacctgcta tggcaaatat tttaaaagga atcgtgggaa
    14581 attggggagc agcgctgatc aatatcggct tgattatttc gatcattggt tcttggttgt
    14641 cttggacgat gctcccagca gaaacaacga tgttgatggc tcgagacggt ctgttgccga
    14701 aaggttgggg aaaaacgaat aaaaaaaatg ccccaactta ttcgttagtt gttactgcaa
    14761 tcttgactaa tctattctta ttgactttct tagttactga ttatgcctat caatttgcct
    14821 attctttatg tacagcggca attttgattt gttatctact tgtcgggatc tatcaagtcc
    14881 agttttcttt aaaagaagga atcaaaaaac aagtagtgat cggtgggatt gctgtagttt
    14941 ttgaattgat gggcatcatt ttagcaggat tttcttatgt ccttttatgt agtattgcct
    15001 atcttcctgg tttttgcttc tactggatcg cttgtcgtga aaccaaacat caaattacgg
    15061 gaaaagaaaa agtaatgatt gggctgattt gtgtggccgc actgctttca atcgggttgc
    15121 ttgctgtagg ctggatcaag atataagggg gaaagaaaca tgaaaatcgc aaatttcggt
    15181 gtagaagaat ggctaaataa atgggaaaag aaagcggtat atgatattgc acaaagctcg
    15241 atcgaagcat tgacattaga cgaactcgtt ggcttagatg ggactagcgt aagtaaattt
    15301 ttcgaaaaac gcaaaaacga accattggac tatggctgga tcgaaggatc agatgttttc
    15361 aaacaagaag tcgcttctct ttatcaaacc gtcgatccgg aaaacatctt acaaacgaat
    15421 ggagcgactg gtgctaatct tttagctcta tacgcgttag tggaagcagg agaccatgtt
    15481 gtttcgatgc ttcctactta tcagcaatta tatgacatcc ccaaatcttt aggtgccgct
    15541 gttgactttg ttcatttgaa ggaagaagaa gattggcagt ttgatttaga acagctagaa
    15601 gccttagtca aacctgaaac aaaaatcatc tgtttgaata gtgcaaacaa tcctacaggc
    15661 acattgctag atcggaaaac tttagaaaaa atcgcagaaa ttgctcgtac agtagatgca
    15721 tatgtattga tagatgaagt atatgcgcct ttaacggata aaggtgaatt cttgtcgatc
    15781 gtagatgtct atgaaaaagg tatagcaacc aattccctat ccaaaaccta ctccattcca
    15841 ggtattcgta ttggctggac agctactgga cctgagttgg cagaagtttt tcgaaagtat
    15901 cgagactaca cgatgatttg cggcggagtc ctgtcagatg atcttgctgt acatgcattg
    15961 aagaataaag aaaaaatatt ggcgcgaaac aaaaagatca ttacagagaa ccttgtgatt
    16021 ttaaaacaat gggtagccaa tgaaccgaaa gttgaacttg tcgctcccaa ttacgtctct
    16081 acttctttca ttaaattagc catcgaagaa gatgaccaga cattttgtat caatttatta
    16141 gaagaaacag gagtactatt agtaccagga agtgcctttg atttaccgaa gcatgcccga
    16201 ctaggttact gttgtaaaaa agaaaccttg gaaaagggat tattcctctt atctgagttc
    16261 ttgaaaaaac aggcctaaac aaaaacactg caaggacagt ctgtgacaac tgttcaagca
    16321 gtgtttttca tttacgctta ttgtctatga gaaggagagt gccctgaagc tatggagact
    16381 cctgaagctt tttcttctgc agtttcttgc tgatggatct cttgtgtatt gtgtcgtaca
    16441 agcaagaagt tgaccaaaac aagaagagaa gtcgaaagaa agacgccgcg ataaccaaat
    16501 gcactggaaa cactggagcc gatcataggc cctactacgt taccagttgc ttggaaagat
    16561 tggttataac tgaagatccg tccagcagct tgatgaggcg aatattttgt gatcaatgct
    16621 tggacagcag ggagcagaca agcatcagag ataccaatca aaaaacgtaa ggcagctaat
    16681 tgccaaacat tcgtgacgaa tgccattggg atataaacca gaatcgcaaa acccaaacca
    16741 atcgcaagta ttctttcact cccaatcttg tcacctaagc gaccaaatct tggagcggct
    16801 atcaaagtgg caatcccagg tatcgaagca atgattccgc tgatcaacgt aacattccca
    16861 tgtccatgca gcaattggcg aatgtacaga ctgatgattg gactaatgga attgttggat
    16921 gcttggatga tcatcgttgt gacgaacata ccgatgacga cgtgtggata tttcaagtct
    16981 ttgaaaatct gtttggcaga aaccatgttt tcttttttca ctgggacaaa tttttcatgg
    17041 acgaaaaaca gactcaacaa gaagacgaaa aataagatga tccctgtaat gaaaaaggta
    17101 gggcgatagc caaacgctga agcagagatc ccgccaagaa gcggtccaag taatgttcct
    17161 gtaacagaac cagttgctaa ggttccaaga acttgaccac ttttttcttt tggcgtccca
    17221 gttgcgacaa gggcagtggc attactgata taaccagaaa aaatcccttg aagcagacgc
    17281 aatgcgacta attgatacac actagtcacg caacccatca aagaaatgac gattgccatt
    17341 cctaatgaag cacgcaacag catcaatttt cttccttttt ggtcggctaa ttttccccac
    17401 caaggagaga taagcgtagt caccaagaaa gtagatgaaa aagtcaatcc gctccaaaag
    17461 ttcaattgtg acgtactata attacctaac gtatctatgt aaagtgacat aaaaggcatg
    17521 actaaactaa atccgatacc agccataaat gttccaaacc ataagacaaa caagttttgt
    17581 tcccaagttt ctcttttcct aaataatttt tcctttattc ttgcagccaa ttagactcct
    17641 tctttctgaa aattttcatc tacagctctt tattataaac tacaatatgt agtttatcaa
    17701 tgaaagtctc ttttttctct ttctttttcg tggtaaactg aaagagtgaa ggatttattt
    17761 tatgagagga aacatggaaa tgaaaaaaag aaatctgtct caagagaaaa tcatcgactg
    17821 ctttcgagaa ctagcagaag agatggatgt tcagcaaata acctttcagc atttagccaa
    17881 acgcttggat atcaaggctc cctcgctgta taaccatttc aaaaatattc gtgatgtcaa
    17941 aacagcgcta acagcgaaac ttctgcagga acttaatgac cagctgcgac gggctcttgt
    18001 gggaaaaagt ggtcaggaag cactgcagat ctatgcagaa acttatcgat cctttgcttt
    18061 ttcaaatcaa gcagtgtatg agttactgat cagtgtaccg cataccaatg aagctgtttt
    18121 attagatgga atccatgaaa cgaatcagat cattttgcag atatttgagg cttttcaatt
    18181 aacgaaagaa gaaaaagttc atcgaagcag ggaacttcgt agtatgatcc acggttatct
    18241 ttccttacgt tttttaggat actttacaaa agaaccaaca atcgatccag aagacagcta
    18301 tttttggatg atcaataact ttatcgctac tttgccttaa acaatcagat tcatttgtaa
    18361 caattttaag atgttcatta aatgaccctt ttataagaga aaattcttgc aactttcttg
    18421 aaaagtgact aagatgagtc tagaaaagct gaaagaagga gcacgagtat gtatcaagta
    18481 attaccatgt tcggggacaa tgagccttgg tggttttttg aagactggga agaagatatt
    18541 gaagaagaag aaacattcga gtctttcgaa gaagcacgac aagcgtacga aaaacaatgg
    18601 aacgaaatcc atcaaaatta tgaatatatc aatgcaaaaa gtaactttct cagcgccttt
    18661 tggaatgacg gagatgagcg ctggtgtgaa gagtgtgacg atgatttaca gcaatacaag
    18721 ggacttgcgt tgttgaaaaa tcatcagccc atcacagtag aaagcagaaa ggaattttat
    18781 gaaacaacta attctagcgg aaaaaccaag cgttgcgaaa gacctaagca aggtgcttgg
    18841 tgctaatcaa aagcacaaaa attattatga aggacccaag gtgatcgtta cttgggccct
    18901 tggtcattta ttaggattga aaatgccgga agatctgaat aaggaatggc agagctggca
    18961 aatggacacg ttgccaatga tccctaaaaa actaggaatc aaaccacttc ctaaaacagg
    19021 acatcaatta aaagcaatca agcagctggc tcagcgaaaa gatgtctcag aagcagtcat
    19081 tgcgacagat gccggaagag aaggggaact tgttgctcgc tggatcttag agtatgtgca
    19141 tttcaataaa ccagtgaagc ggttatggat ctcttctcaa acagataaag caatcaaaac
    19201 tggattcaag caactaagac ctgcgaaaga atatgatgca ttgtatgaat ctgctcttgc
    19261 ccgggcaaaa gcggactggc tggtaggatt gaatgtgacc agagccttaa ctgtgaagta
    19321 cgcggataat ttatcagcag gccgtgtgca gacaccgaca ctagcattag tgagagacca
    19381 agaaaagaaa atcgagcagt tccgtccaca aacgtatttc acgatcacgt tgcaagctgg
    19441 aaaagaacaa gccaaaatgc ttcaaaaaaa tcaatttgct ttaaaaacac aagaagaagc
    19501 acaaaaactt gttcaattga tcagtacaag caaaggaact gtcacagaag tccaagaaaa
    19561 attaaaaacg gaatctgcgc cattgcctta tgatttaaca gagatccaaa gagaagccaa
    19621 tcaacgctat ggctattctg caaagaaaac attaagtctt gtacaaagtt tgtatgagac
    19681 ccataagatc gttacttatc cgcgtacaga cagcaaatat ctgacaaatg acatgaaaag
    19741 tacgatgaaa gaacgattgc aagcagtcag cgactttgct cctgaggtca agcagtattt
    19801 gaaaaacgga gccatcgtcc aacagacaaa agtattccaa gacagtaaag tgaccgatca
    19861 ccatgcactt ttgccaactg aaaacagagc acgttatgaa aaattaagta atgaagagcg
    19921 aaaaatctat caaatgattg tctctcgttt tttaggactg tttgctcaac cccataaagt
    19981 cagccaaaca aaagttacgg ttgaatttgg taaagaacga ttcatttttc ggcaaaatcg
    20041 tgtcgtccaa gcaggatgga aaggcgaaac tgaaactgag acggaaacag tcaaatggga
    20101 aaaaggaatg agaatcaatc ccgatttcgc catcaaaaaa gaactatctg caccgcctaa
    20161 accattgtca gaagcaagct tgcttggtca aatggaaaaa tacagtctgg gaaccccagc
    20221 tacgcgtgca gagattatcg agaaactaat caaatctgaa ctgatggaac gtacccctca
    20281 aggactgcaa gtatctccta aaggtaagca attattagta ttggtaaatc cctctttagt
    20341 aacaccagat ttgacagaaa gctgggaaaa agaccttgaa gctattgctg caggaaagaa
    20401 acaagcagga accttcttga atggaatcga aaaagaaaca aaacgcttgg tgaatgagat
    20461 caaatcaagc aaacaagaat atcaagattt ctcgattacc caaaagaaat gcccagaatg
    20521 tggggccaat ctgcgcgaga aaaacacacg tgacggcaaa atctatgtct gcaccaattc
    20581 agattgcaac taccgcagaa gaaaagatcc aaaagtctct aatcatcgat gcccgcaatg
    20641 tcaccggaaa atggaaatca tcgaaggtaa aaacggtgct tatttccgtt gtaaatacga
    20701 tggaacgaca gaaaaattgc ttgataaaaa agagcagaag aagaaaatga ccaaacatga
    20761 agaacgacgc ttgctgaaaa aatatgcaca agcagaagaa ccagaagaaa gcccattagc
    20821 agcagcacta aaagcagcaa tgaagaagta ataagatatg aaagaggttg tgatagaagt
    20881 ggtcagcttc aagaaataag aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat
    20941 ttcggcttat ttccgaagaa gctacttctg gaacaccatt tattcggaaa aaaggactgt
    21001 gacaagactt ttgtcacagt cctttttcat ttaaaaaaat gtttacttca tttgacgtat
    21061 attattggtg aggcttcaat tcatttggct tcactttttc tgtttctctt atgatataaa
    21121 caggacgctg tttcgtttct aagaagattt tcccaatata tttcccgatg attccaagac
    21181 ataacaattg gattccacca atgaacagga agatcgagac catggaaggc catcctgatg
    21241 taggatcacc aaacaacaat gcccgcaaaa taatgaacaa aattgcaata ccagaaccga
    21301 cacaagacaa agcgccgata aatgaagcaa tcgttaacgg tgcatccgag aagttcacga
    21361 taccatcaat cgagtagttg aataatttcc agaaggacca agatgtttcg ccagccacac
    21421 gttcgcggtt ttcataagaa atatattctg ttttaaatcc gacccagcta aataatcctt
    21481 ttgaaaatcg gttgtattct gttaattcta ggacggcatc caccatttga cgagtcatca
    21541 agcggaaatc acgagcgcca tcgaccattt ctgtatcgct gattttattg atcaactggt
    21601 agaatttttt cgcaaagaaa ctgcgtatcg caggctcgcc ttcacgagtc gaacgccggg
    21661 tgccgacaca atcgatatca gaagtagtga tccggttgat catctcagga agcagttcgg
    21721 gcggatcttg cagatcaaca tccatcacgg tcactaaatc tcctgtagaa gcttgcaatc
    21781 cagcgtacag agccgcttct ttcccaaaat ttctggaaaa tgagacaaag cggacataag
    21841 gataagctga ggctagcttc ttgattgctg ctaacgtacc gtcttttgat ccgtcgtcaa
    21901 taaacaaata ttcgaactca tgggcacctt tgaatttttc aacctcatca aaaaaaagag
    21961 gaacagtttt ttcttcatta aaacatggga caacaattga tactttcatc gtttctatcc
    22021 tttcaatcgt atgtttatat atggtttaca ttcaaaattt aataaacctt aaataacacc
    22081 tttaaaattt gattttacgt aaaagaacag gtattctttt tgtaaactaa cgtatttagt
    22141 ttaccatgtt tcctcggttt atcaaacttt taagaacaat ttttattagt tggcaagtag
    22201 ttttggatag agaaaaagga ggaagttcca gtctattgac taggagcaaa caaaatgaaa
    22261 atacacacac ctatcggctt tttatggtta gatgcagatg aatccggatt gactgctgta
    22321 tcttttcagc caatttcaga aagcgaatca gcgaatcagc gaattttaac gcgcacacaa
    22381 gaacagtttg aagaatattt tgcgggaaaa agaaaagaat ttgatgttcc tttatctata
    22441 aagagaggta cgccttttca gcaaaatgtc tggaaagctt tgtcgaccat tccttatgga
    22501 gaaatccgaa cgtataaaga agtagccgtt gctgttgata gtccgaaagc tgtgcgagcg
    22561 attgggcagg caaatcgaac caatccattg ccaatcgtta ttccttgtca tcgagtgatc
    22621 gggcaaaatg gaaaactgac aggatatatg ggaaacgcaa tagatggggt tgaaatcaaa
    22681 cgccaatt
//
LOCUS       DADVXV010000047        22174 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.048, whole genome shotgun sequence.
ACCESSION   DADVXV010000047 DADVXV010000000
VERSION     DADVXV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.048"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            240..2075
                     /gene="tdc"
                     /locus_tag="KB969_001671"
     CDS             240..2075
                     /gene="tdc"
                     /locus_tag="KB969_001671"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBB6869657.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2380..3858
                     /locus_tag="KB969_001672"
     CDS             2380..3858
                     /locus_tag="KB969_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6869658.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3824..5155
                     /locus_tag="KB969_001673"
     CDS             3824..5155
                     /locus_tag="KB969_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6869659.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5269..7821
                     /locus_tag="KB969_001674"
     CDS             5269..7821
                     /locus_tag="KB969_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBB6869660.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7828..9267)
                     /locus_tag="KB969_001675"
     CDS             complement(7828..9267)
                     /locus_tag="KB969_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869661.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            9613..9975
                     /locus_tag="KB969_001676"
     CDS             9613..9975
                     /locus_tag="KB969_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBB6869662.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(10162..11019)
                     /locus_tag="KB969_001677"
     CDS             complement(10162..11019)
                     /locus_tag="KB969_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6869663.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            11139..12050
                     /locus_tag="KB969_001678"
     CDS             11139..12050
                     /locus_tag="KB969_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBB6869664.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            12057..13708
                     /gene="mdcA"
                     /locus_tag="KB969_001679"
                     /pseudo
     CDS             12057..13708
                     /gene="mdcA"
                     /locus_tag="KB969_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
     gene            13810..14109
                     /locus_tag="KB969_001680"
     CDS             13810..14109
                     /locus_tag="KB969_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBB6869665.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            14099..15775
                     /gene="mdcD"
                     /locus_tag="KB969_001681"
     CDS             14099..15775
                     /gene="mdcD"
                     /locus_tag="KB969_001681"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBB6869666.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            15779..16372
                     /locus_tag="KB969_001682"
     CDS             15779..16372
                     /locus_tag="KB969_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBB6869667.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            16396..17472
                     /locus_tag="KB969_001683"
     CDS             16396..17472
                     /locus_tag="KB969_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBB6869668.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            17497..18366
                     /gene="mdcB"
                     /locus_tag="KB969_001684"
     CDS             17497..18366
                     /gene="mdcB"
                     /locus_tag="KB969_001684"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBB6869669.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            18477..19241
                     /locus_tag="KB969_001685"
     CDS             18477..19241
                     /locus_tag="KB969_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBB6869670.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            19730..21823
                     /locus_tag="KB969_001686"
     CDS             19730..21823
                     /locus_tag="KB969_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6869671.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            21848..22150
                     /locus_tag="KB969_001687"
     CDS             21848..22150
                     /locus_tag="KB969_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869672.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
BASE COUNT         7178 a         3788 c         4725 g         6483 t
ORIGIN      
        1 tgtttgttcg ctttttttag gttatctatt ttagaagact gatttattga aaaattgttc
       61 gcttttttgc gttgaattat cagaaaaatc cgactttatt tatttttgtt tgtaaaaatc
      121 tacgtggatt tgatgttata aaaaaaaaat tctcattttt ggcgctatag tgaagaggtg
      181 ttacagataa acacatgtat ctgcaagaca ttgaccaaca aaatatggag ggaagaaaaa
      241 tgaaagatat ggatatcaag gccgtcttta taggcgacaa agctgaaaat ggaccagttt
      301 ataaaatgtt gttgaacaag atggtagatg aacatcttgg atggagagaa aattatattc
      361 cttcagatat gcctgcaatt agcgaaggag ataagctcac tccagattat ctagccaccc
      421 gcgaccatat gatagaggtc ttggatgaag tcagtcagcg attacgcgca ggatcgatcc
      481 catggcattc agcaggccgt tactggggac aaatgaatgc tgaaacattg atgcctgctt
      541 tattagctta caactatgcg atgctgtgga acccaaataa tgttgcattg gaatcttcta
      601 tggcaacttc gcaaatggaa gcagaagtag gacaggattt tgcttcatta ttcaatatga
      661 cagacggatg gggacacatt gcagcagatg gttctattgc taatcttgaa ggattatggt
      721 acgcccgttg catcaaatcg attcctttag ctgtcaagga agtgctgcct gaaaaagtga
      781 aaaaaatgtc tgagtgggaa cttttgaatt tatctgttga agaaattttg gaaatgaccg
      841 aaagctttac ggacgaagaa atggatgagg tcaaagcagc ttcttcccgt agcggaaaaa
      901 atatccaaag attagggaaa tggctggtcc ctcaaacaaa acactattct tggatgaagg
      961 cgttagatat ttgcggagtc ggcttagatc agatggttgc tatcccagtt caagaggatt
     1021 atcgaatgga tattaatgct ttggaaaaaa caattcgtga attagctgga caaaaaatcc
     1081 caattctagg tgtggttgct gtcgtaggaa cgacagaaga aggtcaagta gacagtgtag
     1141 ataaaatcgt ccaattaaga gaaaggttaa aagatgaagg gatctatttc tatttacatg
     1201 ttgatgccgc atatggcggc tatgcgcgtt cactgtttct aaacgaagca ggagaatttg
     1261 tgccgtatgc ttccttagct gaattctttg aagaacatca tgttttccac cactgcgtaa
     1321 cgattgacaa agaggtatat gaagggttca gagctatttc agaagcggat tctgtcacga
     1381 tagatcctca taagatgggc tatgtccctt atgctgctgg aggaatcgta atcaaacata
     1441 aaaatatgag aaatatcatt tcttatttcg cgccatatgt gtttgaaaaa tcagtaaagg
     1501 ctccagatat gttaggagct tatattttgg aaggatcaaa agctggagca accgccgccg
     1561 cagtctggac agcacatcgt gtattgccat tgaatgtgac cggatatggt caattgattg
     1621 gggcttcaat cgaggcagct caaagattca gagaatttct cgatcatctg acttttactg
     1681 ttaaaggaaa aacaatcgaa gtctatccat tgaatcatcc tgattttaat atggtcaatt
     1741 gggtattcaa agaacaaggc tgtacagatt tgaacgctat caatgaatta aatgaaaaaa
     1801 tgttcgatcg gtcttcttat atggatggcg atgtttatgg tgaacggttt attacttctc
     1861 atactacatt tacacaagaa gattacggtg attctccgat tcgttttgtt gaaagaatgg
     1921 gtctaacgaa agaagaatgg aaaaaagaac agaaaatcac tctgctacgt gcggctatca
     1981 tgactcctta tttgaatgat gatcgaattt tcaattttta tacaaaaaaa atcgccaaag
     2041 caatggaaaa gaaactaaac gaaatcatcc aatagaactg atttttgtgt gaaagaataa
     2101 caagagacat atggagaaca gacaattatt tgcttcatca aaacaattgt atttccccct
     2161 gtttttcata tattcctcgc caagatattc ttttttataa aacgttctat aagttggatc
     2221 gttcgtttca tgtatcaaac ccagttcact aagatcgttc aatggatgtt tcggtgatac
     2281 tgggttttgt actgaatcga tgaaaccttg tcatttctgt tcttgaacaa aaataaaaga
     2341 aaacaaaaac atatgtcgct attgaaagaa ggaataaaga tgaaagatac tggttcatca
     2401 aagcaaatca cgaccatgac ctttatcgga atgacctgcg cccttgtagc aagtgtacga
     2461 aatattccag atgtagcagc aacgagctgg acgatgattt tttacatgct ggttgcagta
     2521 ttattgtacg cttttccaat ctcattgatc tctggtgaat ttgctggaat gtttccccaa
     2581 aaaggtggtc cagaactttg ggtatcgaat gctctaggaa aaaaatgggg gttcgttgtc
     2641 tcatggctgt tatgggtcca aatgtttcct gggatggtga tggtcgcttc agcactcgct
     2701 ccgttgtttg gtaatattat cgataatgtg ccgcttggtt tgaacagcaa atttacatta
     2761 gttgtcattt tagtcgttta ttggatcatc acttttttga atttgaaatt tgatatggca
     2821 aaaatcggcg gaaaagtcgg tgtttggtta ggattgtacg tgcctttgac gatgatgctc
     2881 ttattagggt ttgctgcgtg gatcaaagtt gggatcgtac caaccggaac attaggcagt
     2941 ttttcatggg acaaattaat accagatact acgactgcat cctcatttgt ttattttgcg
     3001 ccgatcatgt ttatttttac tggtatcgaa atgtcctctg tgtatatcac tcgattggaa
     3061 aatccagtta aaacgtatat tcgcggagta tttgccgcgt taatttttat atttttcgtc
     3121 aatattttga atgctttagt tgtagcaaat gtcgtaccaa aaggacaaat ggaattgaat
     3181 aatatcgcgc aatctatttc gatttattgc caaattcttg gtttgccaca tcttattgtg
     3241 aatctgttta gtttacttgt cttcattggt gtagcagtcc aattatctgc ttgggcctca
     3301 ggaccagcaa agacagtgac agaaagtgct agaaaaggtg cgtatccacc aaaattcaat
     3361 ttttggaaga cgaatcaatt tgacgtatcc aaatccgtta ttttgactca gtctgtcatt
     3421 atctcaatct ttgcactttt ttatttgctg attcctggcg tcaatcaagc atttttgatg
     3481 ctcgtaaatt caactactgt tatctactgt atcgtctatg tcatcatggg gatcgcagtt
     3541 ttgagattgc gttatacaca tgcaaagttg aatcgaccat ttagaattgg aaaaaaagag
     3601 aaaaagagca atcttggagt ttggactgtc gttattgttt tatttgcggc aatcggattt
     3661 tctgtcggac tgacgatgaa agctggaaca tggatcaatc taattgcagt cacagccatc
     3721 agtgtcattt tgtttgtagt accactctgt attgaaaaaa taaagaaacc ttcttgggaa
     3781 caggaagtcg ccatgctgct tgaaaaagaa aaaggtgaac ttgatggaaa aaccggcaat
     3841 gaaacggact ctaactaatc gaaatatcca gttaatcgca ttaggtggcg caattggaac
     3901 aggattattt ttaggttcag caaaggcaat tgcatcagca gggccagctg ttattctcgt
     3961 ttatttgata tgcggtttgg ctatttatgg tttgatgcgg gccatgggtg atttattttt
     4021 agcaaatagt acatttaact ctatcagtga tttcgttgac tattatttag gcaaaaagtg
     4081 ggcatttttt gtcaattgga cttattggct ttgctggctt ggagctggac ttgcggaatt
     4141 aacagcaata ggattgtata tccatttctg gtttgtacat gtaccagctt tgataagcgg
     4201 aggtagcgca ctaatgatct taatggcagt caaccttgtt gcagtcaagt ggtttggtga
     4261 attggaatct tttttctcaa tcatcaagat cttggggatt ttccttttta tcttattggg
     4321 tataggattg agtgtctcag attttcatac ccagtctatc ggaatcaaag aaaattttgg
     4381 acagatcgat gaattactac cgtttggctt tgctggaatg gtagtctcat ttcctatggt
     4441 tttattcagt tttgctggaa ttgaaatgat cggcttaacc gttggcgaga caagtgatcc
     4501 gcaaaagaat ttgaaaaaag caatcaactg tctgccttgg cgtattctct ttttctatat
     4561 aggaacgatt ttgtcgattt tatttgttgt tccatggcat tgtttagatt taaaagaaag
     4621 tcctttagtg actatgctgc aagtgatcca ttgccaaggc ggagcagcaa ttgtcaatct
     4681 aatgattttg gttgcttctt tgtcctcagc aaatagtgca gtctacagta ctagcaggat
     4741 tttatatcaa acagcaaaag aaaaaagttt gccccattgg ttttgtgcgc tttctaagaa
     4801 aggcgtacct ttacacggta ttttaattac aggaatgtta ttttttgccg gtctttgtct
     4861 acattttttt gtagctgata gtcgattgtt ttttcagctt ttggcaggca tgacaacgag
     4921 ttgttttcta tttgtgtggt cttcgatctt gtgtgcacat gttcaattta ttaaagaaaa
     4981 gaaacggaac actacacaaa gatataaaga tcttgctttg ttggtgtttt ttacttcaat
     5041 tgctttcagc ttgttattcg aaagcacgac acgctttatt ccttttttat tggttatctg
     5101 gtttgtattc ttaaattttg tatataaaag aataagcaat agaaatatca gttaggccca
     5161 gatacatttt gcaaaacgaa ttatttcaga cccccctgaa ataatcgata cgcctgaaaa
     5221 aacttccctg cgtataataa cagtatcaat taaacaggag gggataggat gaactggtac
     5281 agattgacgg tagaagatgt attgaaaaac tatcaaacat caacagaagg cttgtcgcaa
     5341 gaagaacgac agaaacgcct gactgatcaa ggatataatg aaataaaagc aaggcagcag
     5401 acaaaacgat ggaaaaaaat agcaaagcat tttactgatc tgctgatgat cgtgttgatc
     5461 attgcctctt ttttgaaatt tgcttctagt gaatatattg aaggaagtat tattttattc
     5521 gtagtgatcg tcaatggact cgttagttac tggcaagaaa gaaaagcgga agaatcattg
     5581 aatggtttga agcagctgat gggacaagaa gcgatagtac tatcaaacgg gatgcaagaa
     5641 aaaatccctg cgaaagaact ggtaaaagga gatgtcattg tcttacgtgc cggagatgtc
     5701 gttccagcag atatccgatt aatcgaagca catgatttat tagtggaaga atcgattttg
     5761 acgggagaat cagaagcatc tgaaaaaagt catgccgttt tgacagaaga agaatcgatc
     5821 ggcgaccaga aaaatatggg tttttcagga acgcttgtac aatctggttc tgcagtcggt
     5881 gtcgttgtag aaacaggaaa cacgacagaa atcggtaaaa tcaatcaagc attgcaatcg
     5941 gtcgaacaac aaacgacgcc tctgattaaa aaaatcaacc gattaaacaa acaaattttt
     6001 caaggcattc tttgtttgag cctattctta gttattttta cgacatttcg atatggtatg
     6061 gattggcata tccttctttc ggctacgatt gctttggtgg tgtcaatggt acccgaagga
     6121 ttgccagctg ttttgaccat gattctatcc gttggagtac atgaaatggc aaaagaaaag
     6181 gcgatcatca aaggacttcc ttcggtagaa acattaggtt ctatgacagt gatctgttca
     6241 gataagacag gaacattgac aaaaaatgaa atgacagttg tggatgtagc tgcaaaagaa
     6301 gaagcctgcg tgttgtccat tatgaaaaac tgtcaggaat taaaaacaaa agaagaacag
     6361 aaaacagaaa atttaagtgg caatccgaca gaagttgcgc tgattcgaca cacagaaaca
     6421 gccaatctac ctttgaaaaa aatagaagca aagattccgt tcagttctga atacaaatat
     6481 atggcaacga tgcatgcgga ggaaaaagga gcggtgattt acgtcaaagg tgcaccagaa
     6541 gtattatttg ctaaatcaac tctttcttct gcagaacaag aagcatggag tcagacagct
     6601 gcagaatttg cgagaaaagg tcagcgtgtt ttaggatttg cttataaaaa agtagattcg
     6661 aaacaggaac tcacgcatga gactttaacc caattaactt ttgcagggat cgccggattg
     6721 atcgatccgc caaaagaaag tgcagtcaaa gctgtaaagg aatgccaaca agcagggatc
     6781 tcagtgaaaa tgattacagg ggatcacaaa gacacagcaa aagcgattgc ggaacaaatt
     6841 ggcttaaaac atactgccaa agttttagaa gggatcgatt tggatcttat gtctgatgaa
     6901 gagttgattc agcaagtgcc aatagtcgat gtctttgctc gaacgacacc agaacataaa
     6961 ctgcgaattg ttaaagcttt gcagaaaaat ggagaaatcg tcggaatgac cggagacggc
     7021 gtaaatgatg cacctgcttt gaaaagatcc gatgtaggaa ttgctatggg aatcaaaggt
     7081 agtgaagtaa gcaaacaggc agctgatatg gttttaggag atgataattt ccatacgatt
     7141 gcaaaagccg taaaagaggg ccggcggatt ttggataatt tgcaaaaaac catcaatttc
     7201 ttcttgccaa ctgcattagc tcaaggattg atcttgattt gggcacttat gctgaatcgc
     7261 ccgctacctt tgtccccagt acagatttta tgggtcaata tggtaacgac aatcacttta
     7321 tcttatgcac tagggttcga gtcgccagat ccagaaatca tgaagcgccc accaagagat
     7381 ccaaagcaag gaatcctatc tggttatcat ttgtttcgga tcatctatgt ctccctactg
     7441 atcatggttc ctgcctattt attggctatg cagtttgaag ggcaaagctt acagcaaacc
     7501 attcttctgc aaaatatcgt cttagctcaa gctgtttaca tgatcaattg cagagagttg
     7561 tccaagccgt cattgaacca aggtcttttg caaaacaaag cgctttttct ttcattaggt
     7621 atccttgctt tattgcaagg gatggttatt tttctaccag tcggccagca gctgatcggt
     7681 acagtaagtt taacgatgac acaacagtta ttgattggag caaatgtgat tcttctattc
     7741 ttagttgtag aaatagaaaa agggatcatg aacaaactgt ttcgcaaaaa agaaaaaaca
     7801 gctagagaat acagtcgcta gccgttacta taaaaaagtt ttgaaagtga gttcagtcaa
     7861 acgattgagc tcatttttcg ttggaataga agaaatgtat acaataggga tatctagaga
     7921 atctagaggg aaattggaaa tcaagatatc tgttttttca aaagaaatag tggaaagatc
     7981 ggttagttcg ataggtaaga agcagacacg ttttcctaag taatctttta attcctgctg
     8041 caagaacgcc ttccatgaag gttctccttg gaaaataaaa tagacattga acaaattcgg
     8101 tttgatagaa aaaatcgttt gttggatcag tagagacaag agttggagaa agtaatttgg
     8161 ttcattgatt tctatttctt tttttagatc gttcagtaaa ttctctttct gttgatacaa
     8221 gtgtgcatat tgctgatcat atgtttctaa aaaacgatgg tattgacggt ccaatgcttc
     8281 aatcaatatc ggcgattcat gatattttaa tatgaggaga gccaagttat cagtcagaga
     8341 tgtttttttt agttgatcaa gagacagctc tgaagctagt tcctctacaa acgtttcgag
     8401 gacctctaaa aatggagaat gatgcaggca gcgagcggtt tcttgtccat agttattgtt
     8461 gtaattccaa ctttccagaa agcagaaaga agcaaaagaa agctcagtgt ctttaagata
     8521 aataccttcc gttaaataca attttttcaa tgcagagtca tacagggagg agagtgtgct
     8581 gttggtatgg atagaagaat ctaatcggca attcgctttt atacggatcg tattgataaa
     8641 gaaccaacat gttccgaaaa tctcttctgt ttcaaccgct agttcagttt gactgaggtt
     8701 tcttaaaaat tgaaaataat gggattcatg gatcgaataa tcctcgaaaa aatagttgtt
     8761 atgagtgaaa ggaatcagca atcgatgata aaaagtacga atcgcacgct cttttccaag
     8821 aatacaagct gtatatttcg tcaaatcgat ctgcaagtcg taacttgcta aacgctgatt
     8881 gattttagtc acatgtcttt tcaatgtccc ataagaaagc ccatggtcgg ctagaaaatc
     8941 agggacagca actttttttg taaaaagcag atttttcagc agttcgacac tgactgattg
     9001 tttgaaaaaa atctcccaaa ggtcatttgt taataaattt tgctggtttt gcaaactgat
     9061 tcctgcttga tcgctgatga tgtcccagcc ttcgggcagc tgagagcgaa tagattgaag
     9121 gtcagaaaaa atcgttcgtt cggttgtccc tatgatttca gctaattcat ttacggttat
     9181 ctttgtatga ttcagcaatt gttctactaa agaaacatga cgtcgaatat ctttttcggt
     9241 aatgattttt ttcattagtg aatacatcaa tcagactccc ttctattcta agaatacgga
     9301 gaaaataaac ggtggtcaag tttcaactga tttttcaatc attgtttatt tttctggagc
     9361 atttactgat gataagaatt tcatcatgaa cttgaaaaat gataccacta aaatcaaaaa
     9421 ataggtgggc aaacaataat aaacatttta atagtagatg gtagcaagac caacacaggc
     9481 ggattgaaca tttaagagtt gataaaaaag aaaaatatcg aagtatttga ttagcaacta
     9541 cttgtattca tttttctatt cttacgtggt atctttgaat aaagcgaatc aataagaaag
     9601 agatggaagc agatgctaac gaaaaaagaa ctaatcgatc acatcaatga aacatacaat
     9661 ttgtctccag aatatatttt taaaaaattt cctgattatt gcgtattcag acatcaaaaa
     9721 agcaaaaaat ggtttggggt cctgatgtct gttccagaag aaaaaatcta tgatgatgca
     9781 agtgaccata ggatcatcaa tattcttgat ttgaaggtcg atcctgaact tggcggaatt
     9841 ttgcgaggaa aagaggggta ttttccagcc tatcacatga ataaagaaca ttggatctct
     9901 attgatctac gtaaaataga aaagctagat gaactagcag atttgattga tggaagtttt
     9961 aaatcaacgc aatgaatgtc taggacaata gagaagaggt tgtgacagaa atgtttagct
    10021 tcaagaaata agaaggaatt tacgaaaatt gcttctcaaa tttttgggaa atttcggctt
    10081 attttctaag aaattacttc tggaacaccg tttgttcgaa aaaagagctg cgacaagaat
    10141 tttgtcccag ctcttttttt tttattttcc taaataaaat tcccgcatcg tttttgcaat
    10201 cattttgatc aaaggatgat cttctgtgaa gctagaagat aaataaattg ttcgtgtcaa
    10261 gggcaaatct ttgatttccc gcaagacgaa aggatcattt ttatcgtaag accaagaaac
    10321 ttttgggaaa aagctaacag ctaatccttg cttgacaata gaacgtaatg tcgcaggatc
    10381 atctgtcgtc gaactgatcg tcaattcgat acttttcgct tcaagtgctg catccagtgt
    10441 atgacggaag gcgttgctct ttgacagcat caagatgggg gtgcgttgga tatcttctaa
    10501 ttgcagatgt tcttttttag caagaggatg tttcttagga atggcgacat aaacaggttc
    10561 tttcatgata ggaatattgg tcatgccagg cttcatctcc gaagtgatgt acagtacagg
    10621 atcggtaata tcatctggta aatgatgttg catgatcgtt aattggatat caggatgctt
    10681 ttccataaaa attcggacca agttcggaat agaaacagag gctacctcta aatacaatat
    10741 gacggaagta acgatcttct cattgaccga agacaataat ttgattcctt cttctaatgt
    10801 gtctaatgtc ttgactgcat atggataaaa ttcttctgca taaacggtcg tctcaatgtt
    10861 tctgccgcta tggtaaaaca aagggacacc taattcgttt tccaaatgtt tgatcgcacg
    10921 gctcaaggca ggttgagaaa taaataattc tttggctgct tgggtaacat tttttgtttc
    10981 gaatactttt ttaaaatact gcagatgaag caatttcata attatccatc ccatccatac
    11041 ctttttgtta tggttttttc tttttttggc attttttatt atagcagaaa ttgactaaga
    11101 tagcagtgga aaaagtaagt gctgaggagg cgaggctcat gagtacaggt ttcttatttc
    11161 ctggacaagg cagtcagaag ttagggatgt tagcggatat ccctgaaatg tacatggaac
    11221 gtttagaaaa tgtgacgggg tatcggttag ttgataaaga agaaaactat caagatacgg
    11281 tttttatcca gctagcatta ctgacaaaag cagtatttta tttagatgaa atggaaaaaa
    11341 acggtattca gcctgatatt gcagcaggac attcgattgg tgctttttgt gcagctgttg
    11401 cttgtcgatc tttgagattt gagaatgcag cggaactagt ctatcaccgc gcagtcttaa
    11461 tgaaagaagc ttatccaagc ggttatgcaa tgggcgtagt agtaggtgtg acgagaagcg
    11521 aagctgagga aattgtagca aaaacatttg atcctgacca tccagtttat ctgtcaaatg
    11581 aaaattgtcc gatgcaacat acgttatctg ggagtatcga aggtttatcc gttacgttgg
    11641 cagaagccaa acggcaccaa gcgcaaacag cgaagctgct gaaagtccct gtgccatctc
    11701 actgtctctt gatgaatgat acggtcaaga aattcaagcc gtatatgcag tctgtccatc
    11761 tatctgatgc tagatgtttg tatataaaaa atacggatgg aagagccact caggacgcag
    11821 aagagattcg taaagatttg ttggaaaacc tagctttccc tgtgcagtgg aaccaaatga
    11881 tggacttggc aaaagaatta ggaatggatc tgacgattga atttcccccc ggcaatactt
    11941 tgacaaagct gattcataca aaatttggtg tagataaagg gatccgtacg atcaatctag
    12001 accaacatgg tattgatgac gccacgtttc tatatcaaaa atggagatga ctaattatgg
    12061 aaaaaccaaa ccgcaactgg gcttctaaac gcgaaaaaaa agcgcagcga ttggaaaaaa
    12121 tcagcaactt gctcaatggc aagtatgtag aaactgaaaa aatcgtagaa gtaatggaaa
    12181 aactgattgc tcccggcgac aaagttgtat tagaaggcga caatcaaaaa caagcaagtt
    12241 ttctttcaga aagtcttgaa aaagtagatg cagaaaaagt gaatgatctg catttgatca
    12301 tgtctagtat ctcacgacca gaacatttga atatttttga aaaaggaatc gcaagcaaga
    12361 tcgatttctc ttatgctggt gcacaaagct tgcgtgtcgc ccaaatgatt gaagacggca
    12421 caatgaaatt aggtgatatc catacttatt tggaacttta tggacgctta ttcatcgatt
    12481 tgattccaaa tgttgtttta gtagctgcag ataaagcaga taaagacggc aacttgtaca
    12541 caggtttcaa tacggaagaa acaccaacaa tcatcgaagc tgcagctttc aaagatggta
    12601 tcgtgatcgt tcaagttaac gaagttgtcg attctttacc acgtgtagat atccctggtg
    12661 actgggtaga cgttgtcgtg aaagcagata aaccttatca attagaagct ttattcacac
    12721 gagatcctca aaacatcaca gaattgcaaa ttctaatggc aatgatggca atcaaaggaa
    12781 tctacgcaga acacggcgta caatctttga atcacggtat tggattcaat acagcagcta
    12841 tcgaattgtt actgccaact tatggtgaat cactagggtt aaaagggaaa atcgcgaaga
    12901 actgggtatt gaacccacat ccaacgatga ttccagccat cgaatcaggt tgggttgaaa
    12961 gcatccatag ttttggtggc gaagttggta tggaaaaata tattgctgct cgcccagatg
    13021 tcttttttgt cggtaaagac ggcacgatgc gcagtaaccg aacattatca caagctgcag
    13081 gacaatatgc catcgatatg tttatcggtt caaccttgca attagattac gaaggaaact
    13141 cttctaccgt aacaaaagga cgtttatctg gttttggcgg tgcgcctaac atgggacata
    13201 atcctggcgg tcgtcgtcat tctacaccag catggcaatc acttcgcgac aatgatgatc
    13261 cattagggaa aggccaaaaa ttagttgttc aaatggttga aacatatggt tcaaataaaa
    13321 aaccagtctt tgtcgaagaa ttagatgcac tagctgttca aaaacaagca ggcttagcca
    13381 atgcaatgca ccagtgatga tttatagcga agatactaca catatcgtga cagaagaagg
    13441 aattgcttat ttgtacaaag caaaaacaaa agaagaacga caagcagcaa ttgcagcaat
    13501 tggcggtgtt acacctcttg gaatgactag cacgaaagaa tcactagata gcttgcgtgc
    13561 agccggcatc gtgaaattac cagaagatct aggcatcaaa cgtagtgaag cgaaacgttc
    13621 attattagct gcacaaacca tcgatgattt gatcgaatgg tcagatggcc tgtatgaacc
    13681 accaatgaaa ttcagaactt ggtcataaaa ttggcgagaa aaaccttttg tcgccattta
    13741 cccagatgga agaagaaaga cgaataagca gaacgtgtat gctctgtttt acaaaaaggg
    13801 gagagatcca tggaacaatt agcttataaa tatccaacga aacagccgat caataagaaa
    13861 atccatgtag gagtggtcgg ttcaggagat ttggaaatct tgatgtttcc aacagaaaaa
    13921 acagaatcta ctgtaaaaat ttgtacagga agcgatggct tcggcgaagt atggaacaat
    13981 gtattaacga gattttttga tcgttatcca atttcagcag atatcgtgat caatgacttc
    14041 ggtgctacac caggagttgt gtacctacga ttgacgcaag caatggagga actttcagat
    14101 gaaaaatagt tttgtagaat taaacgccag agaacgagtg aacgctctac ttgacaatgg
    14161 acgtgaattg attgatccat tcgatcaaat catcgcgcca agtttaccag cacaaggaat
    14221 cgtccctgaa agtgatgacg ggatcgttgt cagccgtggc acgatcaatg gcaaacaagc
    14281 agtagtaatc gctatggaag gaaaattcca aggtggcggt atcggtgaag tttccggtgc
    14341 aaaaatcgtt gctgcacttg aacatgtgtt agaagaaaat aaaaaaggaa atgagatctt
    14401 tccagtcatt gtactagata caggtggtgt tcgtttgcaa gaagcaaact acggactgtt
    14461 atctatttca gaaatcggaa atgtaatcat tgctctaaaa caatatgtac cagtcatcgg
    14521 tttgattcca ggacgtgtag gatcatttgg cggtatgtcg attacttcag cattaatgag
    14581 ttatttaatc gcaacaaaaa aagcgagagt cggtttgaat ggaccagaag ttattgaaca
    14641 agaagcaggc gttcgagaat ttgattctag tgacaaagac ttgatttgga atacattagg
    14701 atctcgtcaa cgggtagaat caaaaatcat tgatgaatta gtgactgata gtgtagaagc
    14761 aatcaaagct gctgtcatcg cagcaatgga cgaacgaaaa gacacgcatc gcagtgaaag
    14821 ctcagcattt tatttatcat tacttgattc tttagatctt tcaaaaccaa tggccattga
    14881 cgattacaat gaagcaattg ctaaccatca agcaaaatca attgacttac cagaagtagc
    14941 agaaggaaat gaaccagctg cagcaagtgt tggttacgat tggtttgcgg cactaactgg
    15001 catgaaaaat ccaacttctt ctattagtac tgtgtattat ggtaaatcaa gtaaattcat
    15061 agaagaagcc atcgtgacat caatcgtacc tgatcctaaa aacccgatgt accgtgtacg
    15121 aaacggtgaa gttggtttag ttgaaggttt ccgcatggga caaattttgg atcacgttta
    15181 cgaagaagat aaagacaaaa aagtgaaacg gccaatcatc gttgtgatcg atgtaccaag
    15241 ccaagcatac ggctataacg aagaattgat cggtatccat gtggctttgg ctaatagtgc
    15301 tgctgcttat gcaaaactcc gtcaagctgg acatccagtt attggattga ttgcaggaaa
    15361 tgctatttca ggtgcatttt tagcacatgg attacaatca agccgcttga ttgctttaaa
    15421 caataaagaa attaccgtcc aagcgatgtc taaagaaagt gctgcacgtg tgacaaaacg
    15481 ttcggttgct gaaatcgaag cagctgctga aaaagttcca gctatcgctt acgatatcaa
    15541 taattataca aaactaggag cgatctatca tttcctagaa gatatcaccg accaagctgc
    15601 ttcagaacaa aatgtcagca aagtcatcga agcaatcaat gaagccattc aagatgtccg
    15661 caatacaaat gacacgatgc tgacaaatcg atacacaaac gaaacagcca aaacattcgg
    15721 acgtgtcgaa acaaataaag tccgtgccaa aatggacgaa gaatgggatg cataaaaaat
    15781 gattcaagca catgatattg tcctttttga taaacatgaa atagaagggt tcaccttgcc
    15841 tgaatgggtc gttctaactg aaaagatgtt cggaacagtt cgtcgtgcgt cgacggatca
    15901 cgcagaaata ctaccgattg gtttacgtgg acctgcccgc aatcagagat ggtcaacaga
    15961 aatctcaaaa catgccgtca aacaagtcat tcatccgtgg gacatcatcg aacaagaatc
    16021 gtatagacaa gagaaaatca tggattatcc tgtttatcag caatttcatg ctgctagaaa
    16081 catattatca ggatgtaaat ggggaatcgg cggcagctta ggatttgaat tatcgactgg
    16141 gattccggca gtaaaagaaa ccagtgattt tgatttgctg ctgtacgcaa attcaccgat
    16201 tgaattgcca attcaggtaa ttcaatcgca tcctgctttt tttgagcaat tcgataccca
    16261 agtagtgact cggcaaggcg gtttttcact aaaagagtat ttgagagagc cagagaaaaa
    16321 aattctattg aaaacagtcg aaggacctaa attaaccaaa gaactttggt aataaagaaa
    16381 aagagagaga aagagatgtt tgaaaacaaa aaaatcaaaa tcaacgtaag tgacttccag
    16441 aaagtatcag ctgtaacggc tgttatgatg caaacgatat tgagctttgc tttggcaaac
    16501 agccacagcg caacaaatac agcttttctt ggtacctttt acgtcatcgt taaatacaca
    16561 gcaccaatgt ttatttttgc aattgtttat aatatggtaa aaacaagtca gcatttgtct
    16621 tattgggaat ttttgaaaga aaagtttttt gaactagtcg ttccgtatct tctatggacg
    16681 acggcttatc tttggctatt tccagcagtc caacaacaaa ctccgtatac ggatactgca
    16741 agctttttac tgaaatatgt cacaggtgat ggagcgcctc atttatggta taccgttatg
    16801 atgctgcaga tccaattgtt catgccgttt tttgtttggc tcggttacaa agtatttgct
    16861 aataaaaaat atgtatggcc agtattgatt ggttcaacga ttttatatgt cgcatggtat
    16921 ctgttctatc aaacacaagt attgactggg ccttatcatg acagctggta cttattagat
    16981 cggtttgttg ctagtttcat gatttatggg gtagccgcat ttgtttatca cgaaaaagtc
    17041 tatcaatatt tggacagagt acgttatctt ttcttacctg ttgccttagt tatcgcgttc
    17101 ttttctgtcc gttcattgct cgcacatcca ggagacttga gctttgcgaa tgcaccttac
    17161 ttgaatacga tccaaagttt atacagttta gtcatcatct ttgctgtctt cataggcgct
    17221 tccaaaatga ttgtaaacga ttcgccaaaa ttgccattgt tcaaatggtt gtctgtttat
    17281 gcttatcgta cgtatttagc caatgtattt gttttccaag tactgttatt attgtttaaa
    17341 gatagttggc tgcagttacc ttcaggagtc atgattcttg tagcttatct aatgacggca
    17401 agttgtgcat ttgctttaag ctggttactt catatcattt gggtagctat caaaaaaggt
    17461 ttcagcaagt aatagtagga agaaggagtg agtgtcatga taaatgacga acgaaaaaaa
    17521 gcagtgactc agcaactcgc tgcgttggta gaggaagcat tgatcgcaga agtaacatta
    17581 agtccaaaac ctggattagt ggatgcactg gatgcgggtg cacattccga tatggactat
    17641 gctttatttc ttaagtctgc taagacgcta actccttttt ttgaagaaat ggctcaaata
    17701 gcatggcatc atgctattga tcaggagtta agagaaagaa ttgctgagat tgggcgaaaa
    17761 gcggaaaagg caatgctgat tgctacaaat ggcatcaata cccataaagg agcgatttgg
    17821 gcaatggggc tattgatcag tgtcattgca caaaaaatca gtatggaaca gcctttttct
    17881 ttatcgaaaa tacttgatga tgtcagcaag cttgctgctt ttcctgatac aaaatatcgt
    17941 cataaaaaaa ccactcatgg tcatagggtg aagcaaaaat atggcgtaaa tggtgcatat
    18001 gaagaagcga tattagggta tccgcatatc aggcttgcaa ttcaagcagc taaggagcta
    18061 gataatgatt catatgtaca gaaacaaatg catatgttgt tagttttgat gagttcgcta
    18121 gatgacacat gcgtattgca tcgcagtgat cagaaaacgt tagtggaaat gcaaaaactt
    18181 gctcatgctg ctagtcaaag tgctttacca aatcgtccat ttacagcact gttgcacttt
    18241 tgtcaggaaa accaaatctc tcctggagga agcgcagatc tcttgtctgc aagcttgttc
    18301 atgctgaaga tagaggaatt atggactgcc gacacataca tttgtccgat gttactcaat
    18361 gactaaataa gacaaaattg ctaaaaaaac agtttatgca tctggttatt gactcttcct
    18421 tttagcaagg ctatcataaa aatagttttt tgtaataaaa gataacgagg aagacaatga
    18481 aaaaaatcaa ttatttagca atcattttgt tagtgggcct atgtttgttt gctctgccga
    18541 cccaaggatt cgctgtcgcg ggtggtcatg gtggaggtac atctagcggt cgaagttcgg
    18601 gcagaggttc atttggtggt cgttcatatg ggggcagtta ttttggcagt cgttcttacg
    18661 gcagagattc ttatgggtat tatggtccag gtacaggtcc ttctagttat gagcaaacgg
    18721 gatttcttgc attagctgtt ttgtcagtag gaggggtttc tgctttttct atcgtcaaga
    18781 ataaaagaca aaagaaaagg ctgaaagcgg agatattgtc ccgcatgtca ggaacggcta
    18841 aagaaaagaa agcacagttt ctggaaatcc aaaagatatt catgaagatc caatccgctt
    18901 gggaagaaga aactcctgaa aaagccagaa gctgttatac agacaagctg tttgccgaac
    18961 atcagaaagt tctgcaaaaa aacaaagcag acggtgtaag aaatcatact aaaaaaataa
    19021 ctattcagga agtaggaaat tatcgacaga tccacgaaaa tagttttgcc atccgaattg
    19081 atttcagatg ctgtgattat tcagtcgatc gaaaagatgg gcgattgatc tcaggaagta
    19141 agacacaacg acagtatttt tctcagatat ggtattttga tttttctgag aaagaaaaaa
    19201 gatggcaagc cgattttatt cagccgatta tgctggattg acaggaaata tttatgaacg
    19261 gagttgtgac aaaagccttg tcgcagctcc tttttctgaa taaacggtgt gccagagata
    19321 gcctatcggc aataaggcac gattttgtaa aatatgggaa gcgatttttc aaaatcgctt
    19381 cttatcgctc aaggctgaac atctctgtca caacctctcc actaaatggt gtttaaaagc
    19441 ttgcatctgc gataataaga acaaccaaac gaaaaatagg aagcactatt ttagtttagt
    19501 tgttcttatt acttgatgca ggacagcttt ttcacaacct cttttttgta tagatgggca
    19561 aaatttttgt aataataggc gtatgtcttt ttcgttgagg agatgaaaaa gcatatggct
    19621 tattttttgt ttgctttgct tactttcttt ccacttcaag tggcagaaat atctactttt
    19681 tattatgtaa gcggaaccat atacttgaaa tcagaaggag atcatttcta tgaaaacaag
    19741 aacaattgaa atacttcaca gaatcatgac agcccaatat ccagtaaaag caaaacatct
    19801 agcaagtgag ttcaatgtca gtcagcggac gatccgtcag gaagttcttg aagcgaatat
    19861 ctggttgagc agtaaaaagc ttccggagat ccgtacaatt cgcaacaaag gttttttgtt
    19921 gaagctggaa aaggaaaagc aagctcgatt agaaactgaa ataaaagatg tgaaagacgg
    19981 ctttttgaat cggcgcgaac gtatttttga tctagtttta gccgttgctt acagccgaat
    20041 cccgatccat ctaaacaaaa aagaagaaga atttcaaatc tctaaaagta cattagatga
    20101 agatatgaga cggttacgag caacactggt cagttatggg atagagatcg tcagttatgg
    20161 aaagcaagga ctggtttata aaggttcaga acgatctatc cgtacgatga tctatgattt
    20221 tatcaatcag aatctgggaa tgaccgactt ctttatgaat caagatgcac aattaacacc
    20281 ggctcaaaaa atctttctcc attattttcc tttggtggaa atcaaaaaaa tacaggagat
    20341 ctattccaat aagttgttga aacaagaaga tgatatttat aaaaaacaaa tcctgctttt
    20401 tacattgatc tggatccagc gaatcaggaa acatgaattt atctctgcca ttaattggaa
    20461 aaatacagaa ataaaagaca gtagcttttc tgcatttatt gaccacatga tcgaggaatt
    20521 tcaattggac aatgtcccgc aagtagaaag aaattatctt cgtttcacta ttgagacgtt
    20581 caatgctaga gatatctcca attcaatcga gtgggtacaa gctcaattac taacgatcca
    20641 attgatccaa tttgtagaga acgagacaca cgtacctttc catctaaagg aagaagcttt
    20701 attcgaaaat ctctataagc acatggctgc actgattgta agaatcaaga atcatatcca
    20761 agtcatgaat ccattgaaag aaaacatccg aacaaattat ttcccaatct accgcgcagt
    20821 cactcatttt gttcctacga tcgaagaagt aattggtggc aagatactgg aggacgagat
    20881 agcttttctt gtcatccact tttcgacgat cgccagtgta atcaagcgag acttgaatta
    20941 tgtttataaa tcagtcgttg tctgtaacca tgggatggct actggaaatc tgttagcaga
    21001 gaatctgaaa gaaaagtttc ctcagatcga gattactgca gttttaagtt caaaagaaat
    21061 cgaattagta gataaattgg atgtcaatct ggttttcagc acctttcaat tgaattatcg
    21121 aaataagccg cttttagttg tcgatccgat tttaactgag acgaatatct tggttataga
    21181 agactttttg aaaagaaatg aagaactaca gcggttagag cctaacagtc atgaatcgac
    21241 ggagttattc actcaaataa tagatgtcat gaaagaaagt ggtggccgag tagatcgaat
    21301 catctatggc aagttagaaa aattattcga aacaaacaat ttagaaatca acaaaaggga
    21361 gatccagcct atgttaaaag atattttgac ggacagcaat atcatgatca aagaaaaagc
    21421 cactacttgg gaggaatcga ttgaactagc tgctagacca ttggttaaag aaaacattgt
    21481 cgaagagcgc tatgtcgaag cgatgattcg tgcagtgaat gattacggac cgtatatcgt
    21541 gattggcaaa cacatggcac tagcccatgc ccgaccagaa gatggggtca ataaattagg
    21601 agtcagcgta gctacgattg agcaaccaat cgatttcggt aatcctgaaa tggatccagt
    21661 aaagattatt ttttgtttgg cagcagtaga ctcctactcg catctgaaca tcatgaaaga
    21721 actaattgaa ttgatcaaca acgaagagaa gttggatcga ttgattgaat gcacaaatat
    21781 cgaagatttc aaacaactgc ttttttcagt agttgagaaa taataaatga tacgggggag
    21841 aacaaagatg aacaaattga acattttatt cgtatgcggt gcaggtttag gaagtagttt
    21901 tgcagcacag atgtctgctg aggatgtttt gaacaaatta ggagtagaag ccaaactgga
    21961 ccattgtgat atttcttccg cagtttccat gaaaccagat gtgatcatca cagcagaaaa
    22021 ttttcgttcg cagttcgaaa agttcgcagt tgatcctaaa acggcgatga tctatttgaa
    22081 aaatattgtt tcaaaaaatg aaattgaaga aaaaatcacc ccagttctgc aagataaggg
    22141 agttatctaa atacaaaaag aaaagagggt aaaa
//
LOCUS       DADVXV010000048        21814 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.049, whole genome shotgun sequence.
ACCESSION   DADVXV010000048 DADVXV010000000
VERSION     DADVXV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.049"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(531..2027)
                     /gene="lysS"
                     /locus_tag="KB969_001688"
     CDS             complement(531..2027)
                     /gene="lysS"
                     /locus_tag="KB969_001688"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBB6869673.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="KB969_001689"
     CDS             complement(2138..3142)
                     /gene="dusB"
                     /locus_tag="KB969_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBB6869674.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="KB969_001690"
     CDS             complement(3143..4030)
                     /gene="hslO"
                     /locus_tag="KB969_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBB6869675.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="KB969_001691"
     CDS             complement(4247..6358)
                     /gene="ftsH"
                     /locus_tag="KB969_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBB6869676.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="KB969_001692"
     CDS             complement(6448..6993)
                     /gene="hpt"
                     /locus_tag="KB969_001692"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBB6869677.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="KB969_001693"
     CDS             complement(6993..8438)
                     /gene="tilS"
                     /locus_tag="KB969_001693"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBB6869678.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8558..9028)
                     /locus_tag="KB969_001694"
     CDS             complement(8558..9028)
                     /locus_tag="KB969_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBB6869679.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9074..9499)
                     /locus_tag="KB969_001695"
     CDS             complement(9074..9499)
                     /locus_tag="KB969_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBB6869680.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9566..9835)
                     /locus_tag="KB969_001696"
     CDS             complement(9566..9835)
                     /locus_tag="KB969_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBB6869681.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9846..11441)
                     /locus_tag="KB969_001697"
     CDS             complement(9846..11441)
                     /locus_tag="KB969_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6869682.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="KB969_001698"
     CDS             complement(11456..14977)
                     /gene="mfd"
                     /locus_tag="KB969_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBB6869683.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14994..15554)
                     /locus_tag="KB969_001699"
     CDS             complement(14994..15554)
                     /locus_tag="KB969_001699"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBB6869684.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15907..16881
                     /locus_tag="KB969_001700"
     CDS             15907..16881
                     /locus_tag="KB969_001700"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6869685.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            17051..18451
                     /locus_tag="KB969_001701"
     CDS             17051..18451
                     /locus_tag="KB969_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBB6869686.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18529..19251)
                     /locus_tag="KB969_001702"
     CDS             complement(18529..19251)
                     /locus_tag="KB969_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6869687.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19330..19836)
                     /locus_tag="KB969_001703"
     CDS             complement(19330..19836)
                     /locus_tag="KB969_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6869688.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19959..21758
                     /locus_tag="KB969_001704"
     CDS             19959..21758
                     /locus_tag="KB969_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBB6869689.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         6054 a         4752 c         3911 g         7097 t
ORIGIN      
        1 agagtgtttc ccgattcatt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagcgattgt caactctttt ttaaaagttt ttttcgattt cgtttttcga aatctttcgg
      121 caactcattt atcataactt atcgtttgtt atttgtcaag aacttttttg aagttttttt
      181 cgatagaatc aagcttcgca agtggttctt ttttaacgac tcagttatct tatcatgtcg
      241 ttagtaacat gtcaataact tttttgttat gtttttgaat aaatattttc ttctgtcttt
      301 tggacaagta ataatatacc aactaaattt agcttggtca acgaattttt tgtatttttt
      361 caagtttttt tcaataaacg attattcata acttttcttt ctttatcgtt cgttttcgtc
      421 ttctttaatg tctagaatag tcggcattag cttttgaact ttcgttatta tttattcctt
      481 tctacacagc aaaagctgcc taaggaattc cttagacagc ttttattcga ttatctcatt
      541 gttgggaata gcaaaacatc ccgaattgat tgtgcatcag ttagcaacat tactaatctg
      601 tcgatcccga tgcctagacc accagttggc ggcataccgt attctaaggc ttccaagaag
      661 tcttcgtcta caccgtgagc ttcgtcattt cctagttcac gttctttttc ttgcgcttcg
      721 aatctttctc tttgatcaat tggatcgttc agttctgtaa aggcattagc aaattcgcgc
      781 cccactatga atagttcgaa tcgatctgtg aatcgaggat cttctggatt tttcttcgct
      841 aaaggcgaaa cttcgactgg atgtccgtat acaaacgtcg gttgtgtcaa tgtttcttca
      901 acaaatgttt caaagaattc attgataaca tgtccgacac ccatagcttc ggttacttct
      961 acattgtgtt tttcggctaa agctaatgct tcttccaatg tcatttcttg ccagaagtct
     1021 acaccagttt gttctttgat tgcatctacc atatggatgc gtttaaagtc actttctaag
     1081 tcgacagctt gtccatcata tgtgattttt gctgttccta gtactttttc agctgcgtta
     1141 cggataatac cttctgtcag attcattaca tcattgaaat cagtatatgc tgtgtatgct
     1201 tctaacatcg taaattctgg attatgtgta gtatcaattc cttcattacg gaaaacgcgg
     1261 ccgatttcat aaactttttc cattccgcca acaattagtc gttttaaatg aagttctagc
     1321 gcaatacgca aatataaatc aatgtccagt gcattatgat gcgtgataaa tgggcgtgcg
     1381 gcagctccac ctgcctcatt gtgcaatact ggtgtttcta cttcaatata gccattgcca
     1441 tctaaatagc gacggatttc gctgataatt tggcttcgtt tcataaatcg gtcaaagctt
     1501 tcgcgattac tgattaaatc caagtagcgt tgtctgtagc gttgttcaat attcgttaag
     1561 ccatggtatt tatctggcag tggacgaagt gcttttgaca aaatcgtgat ttctgaagct
     1621 ttgatagaaa cttcgcctgt gtctgttttc atgatttgtc cagttacacc aaagaaatct
     1681 ccaaggtctg catgtttgaa tacttcatag gcctcatcac ctacttggtc ttttcttaca
     1741 taaatttgaa tttggccttc acgatcttgt agatgcgcaa atccagcttt cccttttcct
     1801 cggcgagtca tcatacgacc agctacacta gcggtcaatc ccatttctgc tagttcttct
     1861 tttgttcttg gatcaaatag ttcatgcaat tcttctgagt tgtgcgtgcg ttcaaatcgt
     1921 tttccaaatg gatcgattcc atcttcacgc aattgttcca ttttttgacg acgtacaagc
     1981 atttgatcat ttaaatcttc tacttgatgt tgttgttcct gtgtcacaaa agttcctcca
     2041 ttctcatgtt aatctctttc ctataatgcc aatgaaacac aaaaaaagca agccgaactt
     2101 ggaatttcgg cttgaaaatt cacgaaaaac ttagaaatca caacgtttgt ttcaatagta
     2161 ctttttccgc tttttctaca aattgatcca gcaggtcatt gatttcttgc tgtttttctg
     2221 tctgattgat tgctactttc actttcgctg ctcgaggaat cccttttaaa taataagccg
     2281 catgtgttct gaattctcta caagctactt tttctccttt gagatctgct aagcgttgta
     2341 aatgaagttt agctgtagca attttttcgg ctggtgttgg ttcaggaatc agttcccctg
     2401 tttcgagata atgctgtgtg cggtgaatca tccatggatt gcccagcgct gcacgaccaa
     2461 tcatcacacc gtctgcaccg acatagtcaa gcatccattt tgcatcttct ggcgttttga
     2521 catccccgtt ccccataaat ggaatcgtca aatgtttttt cacttctttc aatacttccc
     2581 agtccgcttt tccttcatac atctgaaccc gtgtacgtcc atgcatagcg atggcacttg
     2641 ctccagctga ttgtgctgct aatgcatttt ctacagcaaa gacgtgctct tcatcccaac
     2701 caatacgcat cttgattgtt actgggatat ttactgctga agaaacagct tggaccattt
     2761 cgtatacttt ctcaggatct aaaagccatt ttgctcctgc ttctgctttg attactttat
     2821 ttactggaca gcccatattg atatctatta tatcggcagc tgtgttttct tcgacaaatt
     2881 gagcagcttc aactagacta tctttatttc cgccaaatat ctgtaaactt aatggatgtt
     2941 ctgtttcttc aatgtggagc atctctaaag tttttttgtt tctgaaatga ataccttggt
     3001 cactgatcat ttcacatacg actaagcccg caccaaattc tttgacagtg actcgaaatg
     3061 ctgaatttgt tattccagcc atcggtgcaa caacgacacg attagggatt tccacattgc
     3121 caattttcca tgtgtgttcc acttaaatcc ctcctaaggc ttctttcttc aatccatcta
     3181 attcttcttc gctatacttg tatttgttat tacagaaaga acaaaccgct tctgcaccgt
     3241 gatcttcgtc tatcattgct tggatttctt ctgcacctaa cgcgataatt gcttctgcaa
     3301 atttttcttt tgaacagtca catttgaatt gaacaggcat tttttccaaa atgttcaatt
     3361 cttctgtacc aagcaatcct ttcaatattt cttctggtgt ctgtccttca tctaagaggg
     3421 tagagattct tggtgtcgtt tttaattgtt cttcgatctt gctgattgtt tcttcatcgg
     3481 cacctggcat gatttggatc atgaatcctc ccgccgtctt gatgctgtcg tcagtattga
     3541 ccaatacact cagtccaaca gctgaaggga tttgttctga gatagcaaga tagtaagtaa
     3601 aatcttcagc gatttctcca gaaacaatcg gcgtttgccc agaaaaaggt tcttttaatc
     3661 ctaagtcttt tgtgacagta aacattcctt gtgttccaac tgctccccgc acatcgattt
     3721 taccttcact atttagagga agactgagat gcggattttt gatgtaacct ttcacatctc
     3781 cctttccatt tgcatctact acaattcctg ttgctggacc atcgccttgg attcgaacag
     3841 ttagtttgtc ttctcctttg agcgtcgcac caagtagcag actaccgacc aatgtccgtc
     3901 ccaaagcagc tgaggaggtg tgccaagtat catgacgtct ttgtgcctcc gctacggtat
     3961 ttgttgcttg aacggcgtat gctcggacga atccgtcgtg agcaagtgcc ttaaccaaat
     4021 aatctttcat ttgttatgta ctcctttttc cgtttttaaa ctcatagtga atcatactag
     4081 caactactgc ttttttcaac tttggaatgc ttcttttaaa aataattcag aatcatctag
     4141 aaaacaggac atcaccctat ttacaactta aataaagaaa tctcccgaaa accggttttt
     4201 gttccggttt tcgggagtca tatcagatca attgacctat atttttttat ttgtattgat
     4261 cgtctgaatg attatcttct gattgttgag aatctgaatc atgttctgct ttattttcct
     4321 cattcagttc atgttttgct tcttcaaaat cacgtttttc ttccgcttgt ttttcagcgt
     4381 ctttttcttc caaagcacgt tttgcttctt caaaagtttt cgcttctttt tcgcttggat
     4441 aatcatttga ctcagtacct tcaggcatca caccgtgttc aaacaatgac ttgattgctt
     4501 tggcatccaa tgtttcgaat tccaaaagtt tttcagcaat cagtttatgc tgtgcacgat
     4561 gagcttcgat gatttctcga gctttatcat gagcttccat caagattttt cgtacttctt
     4621 gatcaatctc gaaagcgact tgttccgagt aagcttttgt ttgaccatag tcgcggccaa
     4681 caaacacttg atggtttcct tcatattgaa caggacctaa acgatcactc attccatatt
     4741 ctgttaccat gcttcgtgct agagctgtcg cttgctcaaa gtcattggaa gcaccagttg
     4801 attggacatt gaagatgatt tcttcagctg tacgtccacc aagtaagcct acgatttgtt
     4861 caaacatatc ttctttcgtc atcaagaact gatcttcttt tggtaaagcg atcatatatc
     4921 cgccggcgcg tccgcgaggg atgatcgtta ctttgtggac gacccgagcg cgactcaata
     4981 ctaatccgac aatcgtatga ccagcttcgt gataagcaac catttcgcgt tcttttttgc
     5041 tgattacgcg atctttttta gctggacctg caatcacgcg atcttccgct tcatcgatat
     5101 cagaagcatc gattttcttt ttatttcttc tagcagctac taacgctgct tcattcaaga
     5161 cattttctaa atctgctccg gcaaaacctg gtgtctgttg agccacaact ttcaagtcaa
     5221 cgtcatctgc catcggttta ttccgtgcat ggactcgcaa gattgcttca cgacctttta
     5281 catctggacg tccaactaaa atctggcggt caaaacggcc tggacgtagt aacgctgggt
     5341 ctagtacatc agaacggttg gttgcagcaa tgacgattac tccttcattt ccgtcgaagc
     5401 catccatttc tacaagcaat tggttcaatg tttgttcgcg ttcatcatgt ccgccgccca
     5461 taccggcacc acgttgacga cctaccgcat caatttcatc aatgaaaatg atagctggtg
     5521 cgtttttctt cgctgtttca aacaaatcac gaacacgact tgctccaaca ccgacaaaca
     5581 tttctacgaa atcagaaccc gagatcgagt aaaacggtac tccagcttct ccggcaacag
     5641 cttttgctaa taaggtttta cctgttcctg gaggtccttc taaaagtaca cctgccggga
     5701 tacgggcacc taattcaaca aatcggcgag gatctttcag aaattcaaca acttcaacta
     5761 gttcttgttt ttcttcttcc gcacccgcta catcagaaaa acgtacgcga ttagcttttt
     5821 tgtctgcttc tttggctttt gatttaccaa agttcatgac acggccgcca ccgccaccgc
     5881 cgccgccttg ttgtcccatc atcatgtaaa agaaaaagat gatgattacg attggcaaga
     5941 agctaagcaa tagggaaacc catataccgc tgcttgattc ttcttttact gttgtagcaa
     6001 ctttgttttc ttttgccagt tctgttactt ggctcaatgt tgtatcattt ggcaaaatga
     6061 ttgttgtgaa atgggtagta gtcgtatctg ttgaacctaa gatagctaac ccaccgctgt
     6121 tagcgacggt ctgctgttct ttgtattcac cagtgatctt atatacacca tttgcaggct
     6181 gcacttcaaa ttctttgatc ttgcctgctt gtagttgttc tgtgaatttt gagtactcga
     6241 tatctgacga tcgctggccg ttattaccaa aaatgaaata aacgaccatt accatcgcta
     6301 agattacgag gacataatac aaggcatttt tcatcatgcc gttgttcttt ttgttcatag
     6361 ttgccctccc taagcgtcaa tttaatttaa cagtttttta tcaatcctga ccattctatt
     6421 gtaccataat ttaattgaga tacagcatta atttgattga taaacactag gtttcaatac
     6481 accgatgtac ggaaggttac gatatgcttc tgcataatcc aagccataac cgaccacaaa
     6541 ttcatttggt acgttgaagc caacataatc tgcttcgata tttactactc ttccttcagg
     6601 tttgtcaagt agtgtaacaa ttttgactga ttttgctttg cggtatttga aaagatccac
     6661 taaataagca agtgttcttc cgctgtcaat gatatcttca acgatcaaca gatcgcgacc
     6721 ttctacattc gtatctaagt ctttgacgat ttttacttcc cctgacgaga ctgttgcatt
     6781 cccgtagctt gaaacatcca tgaaatccaa ttccaaatac gtatcgatag aacgaacgat
     6841 atctgccatg aatggtaccg ctccttttaa gacacctact actaggggat tggtgttttg
     6901 gtaaatttct gttaactctt tgcctagttc tttgcaacga acttgtatct cttcttgtga
     6961 gatcaaaatt ctctcaatat ccttttccaa catcaggttc tccttccaat tgcttctttt
     7021 tgatatttgt aaagaagtat gtagtgtatt ttatcagttt cttcacgaat actcaaatat
     7081 gaaaaggcaa aaggtatcaa gctatatata tttcttttgg catctgtaat gatccaagca
     7141 tgctgccttt gtgaattagg tactttctga tcgataaaat atctagatac tttttttgtg
     7201 agattctctg ttaatttaat gcggtctcct gcttttcttt tttcgacata cagttgcaca
     7261 tcagcaggaa tccaaatgtc atgagaaaat agagaccatg aatctgttgc tttgatgtcc
     7321 cctgcatttt caggtttgac cagaccaatc cattctgttt cattcaaata tattccttgt
     7381 tctggaatca gcaacaagcg ctggtcttct gtctggctag ttgcttgttt ttctttttta
     7441 gagagtacaa caaaatgata ctctcttttc agtatccaat tattgccaat actgagttgc
     7501 cattggcttt ttttctgttg ccactggtct aaaatcgact ccatttgttg ttctttcaaa
     7561 ataattcctg tttttgagaa tgctttgtcg aaaaaggagt aaaaaaaata gtatcgttca
     7621 gcatctgtca tttcttcaat catttctgca gaaaatcgaa attgttcctc ccactgttcg
     7681 acttcctttt cgatcaactg tcccatatat ttttgaatga cttggtctgc ccattggatc
     7741 tgttgcgaaa attgctggaa atgtctcaac gcctgtgtat tttcttgttt caattgagga
     7801 actaccaaat gacgaagccg atttctctgg atatctaaca attggtttgt ctgatcctca
     7861 aagtaaacaa gctgcgattc cgctgcataa gtatataggt cttctttgct aaaactcagc
     7921 aacggacgaa tcagtctgcc cgtagcaaat ggttgtactt ctttgattcc agaaaaagta
     7981 tttaactgtc ccccacgaac gattttcatt aacaccgtct cgatttgatc atctccgtga
     8041 tgagcagtca tcaacgtgtc atattgtcct tcttccatca cgcgagtgaa ttcttgataa
     8101 cgaaagttac gagcttctgt ttctatggcg gatttggctg gatcttccca aatacttaca
     8161 tataaaggga gattcttctc ttcacaatat gagcgaagat aggcagcttc ttctgctgat
     8221 tcttctctta attggtgatt gatgtggacg atacctaaag aaaaaccgat ttggcgttgc
     8281 acttgtaaaa gtaaatggag caaaaccatc gaatcaacac cacctgatac cgctgctaaa
     8341 attctcgatc cttgttgcca gaatccttgt tcattcccgt gccgaataaa tgactgctgt
     8401 aatagcggtg cttttttccc gcctttttca acgttcatcc tttccacacc ctttcttcct
     8461 aaaaaaaaga gagcgggaaa acgtctaaaa cgacaattaa cctgccctct gttgatacta
     8521 tgacccaaat agtcgcacta tcattatttg cggcttttta gctgcgacgt ccgccacggc
     8581 caccgcgctt tccttctgtg tttcgcttca atgaagataa gcggtcatcg ctatctttca
     8641 aaaatgaact catcaatgaa tcgaagtctt ctttttgagc tgaaggttga ctgcgagaaa
     8701 aagatttttt ctgtgctgga cgatttcggt tgtcacgggg atctttttgt tgatattttt
     8761 taggacggct ttcttctcca gattcagcag gttgttcctg cgctttccgg atagatagtc
     8821 cgatttttcc atcatcattt actgaaataa ctttaactgt tacttcatct cctacactta
     8881 aaacatcatg gatgtctttt acatagccat ttgacacttc gctaatatga actagacccg
     8941 tttttccagc acctagatca ataaacgcac caaaatttgt gattcctgat acttttcctt
     9001 gcagttttgc tcctacctcg attgacataa aaaaaatgtt cctcctaatt atttcccttt
     9061 tttatattcc tgcttatttt gcagttgtag aactagttga ttgatctgtt tcatttgtcg
     9121 agctgtctgt atttgattct aatataggat aaactttttc accgtctttt gagtaaaaga
     9181 atttgcttct ggcaagttta gctacatact catcatcttt cagcaatgaa acatcttggt
     9241 gcagctgatc aacgtctgcg ttgacttctt tcatttcagt atttgcttcg actctcaatt
     9301 cgttcaattg atgcatcctt tgcatgtcat ggaaaatctg cacacctatt atcgcgaaaa
     9361 tgaccaaagc accaacaaaa attgcagcca gtctgcgtct tcgaaaaatc agttgacgtt
     9421 gttgttgctg aaattcagca tactttttct ttgcatattc cgtatctagc gcagcgattt
     9481 tattgctttt tttcgtcact tggattcgct ccaatctttt tgattgtctt tttcattata
     9541 ccaatatcgt gaaagcttgt ctaatctatt tctctagtgt ttctgtgcga ttttcagaaa
     9601 taatttcgta cattttttgt gcatcttctt ttttggttga ttcatgtaat tccgtaattt
     9661 tcacttccaa cgttttgttg ccaaactgga ctttcaaaat atcgcctact ttgacatcac
     9721 tggaagattt cgccaattta ccgttgattt gaattcttcc tttatcagct acttcttttg
     9781 ctactgatcg tcttttgatg attcgggaaa tttttaaaaa tttatctaat cgcatatctt
     9841 attcctcact ttttaatttt tttatttaat cgcaggattt tcttaccaaa aggcaacatt
     9901 agccattctc gtactgtaaa cagacgaaga cgaatcactg cataaatgaa cacagaagcc
     9961 ccgatcccaa ctcctatcac gctgacaaaa aaagcagtgg aacgatgagt tacaggacca
    10021 aatactatat tcaatacacc ataatacagc agcagtacta ctgtcataca aagaaggctg
    10081 aacatcaact tccgtccaaa atgccgttct ttccaaaaag catttagctc ttttgtttca
    10141 attcgaacaa aataccaaag cgtcacacct aatcctaaaa gggtagacag gcttgcacct
    10201 gctgttccta ataaaccggt cagaaaagaa gtagtcaatc cttttaccaa tagtccccat
    10261 cctgcgcctt ttaaagaagg gcgaaacgag ttcttgcttt gagcaatact ttgataagct
    10321 tggatgactg cagtgaaagc aatggaaaaa acaaataata caagcgctgc atttcccgca
    10381 taatctttaa acaacgcata attgatataa gggagcagca aggctaatcc caaagacgca
    10441 gctaatgcta aagcggtcgt caatctaaga tagattttgg ctgtctgtaa aaactgacga
    10501 tagatccggt tggtcaaatg acgagtcaac gcaggcagga atgtcgcact taatgcagtg
    10561 gcaatcacta aacctaattg tactaaaggc tgacctcgat catagacccc ttttgctatc
    10621 ttcgcaccgt attctgacag tccgtaaact tccaaagcat tttttacaaa gaaagagtcg
    10681 atcagctgga aaaagataag caatccacta taaatcgaaa ccagtccgcc ttctaccaga
    10741 aaacgccgga tcaagggctt tgacggctgt ttgaacaatg gaaaccgtcg gaagcttaac
    10801 gctcctccat gaatcttttg ttcatagtag tgaaggatcc catatgcgca taaaccgcca
    10861 aaaacagctc cactcattgc tgccgtccct gtttggtaca ccgtccatcc aagctttcta
    10921 aaagcaaacg cactacagac aatcacaaaa acacgaacga actgctcaac tacttgagaa
    10981 acagcagttg gttccatcaa gaatcttcct tggaaattcc ctcgataaaa agatagacca
    11041 ggcatcagca aaaaggtaaa ggaaactact tggatcagcg gtttcaattg tatgtctccc
    11101 atcatccaag caatccagct gctaaatgca aagacaaaca accacaaaaa gacacctgtc
    11161 caaaatacta agggataaag attttgcaaa gcttgctttc gctcgaaagg attctttctt
    11221 tctgcaacgt actttgatat gaactgcgga agaccggata aagctaaagt cattgctatc
    11281 ccataaattg gataaacttg ctgataaaca taaaaacctt cgtcgccgac taagttttgg
    11341 aggggaattc ggtaaagggc acttaatact tttgctatga aagaagcaat cgtcaataca
    11401 aatgctcctt gcatgacgcg ccgcatttct ttatgatcca aatcattgct ccttcctacg
    11461 ctgacagata tttttgctca cgcaacgctt tgacaaactt ttggatttcc tgaagccata
    11521 ctgcttcttc catttggttg gggatcgtca agcgtatcac catctgttct ttttcaacgc
    11581 ctagactggc ttttagtttt gtcgctgtca gtgcttcgaa taactgttcc acactatagc
    11641 gttttgttcc aactttactt agagtaaaga ctatatgcgc ctcctgtttc cttatcgttt
    11701 ctaggagcgc tcgatcgcca tccattttga tctgcccaat tgtcaagaga tgtgctactt
    11761 cttctggata ttctccaaaa cggtcgagca gatcatcttc tagttcatct agcatttctt
    11821 gcgaatcaag ttcacgaatt cgtttataga tctcgatttt ctgccgttga tctgccacgt
    11881 atgtttcagg tagatacgca tcgacaccga ggtcgatctc aacagtggtc ttctccactt
    11941 gactattctt tccttgttta cgagaaacag cttcgcttag catttgagaa tacatatcga
    12001 aaccgactgc atcaataaat ccatgctgct gagcacctaa gagattacct gcaccgcgaa
    12061 tggaaagatc ccgcatcgca atcttgaatc cagatcccag ttctgtaaaa tctttgattg
    12121 cctgaagacg tttttcactg acttcgttaa ggatcttctg ctgctcatac ataaagtaag
    12181 catatgcgac acggctgctt cttcctaccc gccctcgcaa ttggtataac gtggataatc
    12241 ccatataatc agcgttctca acgaacaacg tatttgcgtt cgggatatct actcctgttt
    12301 caatgatggt tgtagtgaca agaacatcat attgaccttc aataaattca aaaagcgtat
    12361 tttctaattg cgcctctgtc atttgcccat gagcataacc gatccgtgct tccggaacga
    12421 gttcttggat ttcttctact ttttgttcga tcgtttctac ccgattatat aaatagaata
    12481 cttgtccacc tcgtcccatt tctcgatgga ttgcttcgcg aatagcccca ggattttttt
    12541 ccataacata cgtttggatc ggataacgat tcgcaggcgg tgtttcgatt actgaaagat
    12601 cccgcacgcc taacatcgac atatgcaaag ttctcggaat cggtgttgca gtcagagtca
    12661 aaacatccac ttgtgcacgt aactgtttca atcgttcctt atgttttaca ccaaaacgtt
    12721 gttcttcgtc aatgatcagt agacccaaat cgctaaattc aatatctttt gacaaaattc
    12781 ggtgggttcc tacaacaata tcaacttgac ctgtacgcag ttgttcgatg gtttcttttt
    12841 gttgctttct tgttctgaaa cgacttaata gcccgatatt tacggggaaa ccttcaaatc
    12901 tttccagcat cgtttcatag tgctgctgtg ccaagatcgt tgttggaact aaaaaggcta
    12961 cttgtttgct ttcctttatc gctttaaagg ccgctcgaag cgctacttct gttttcccat
    13021 aaccaacatc acctacgagt agtcgatcca ttggtttttc tttttccata tcccgtttga
    13081 tctccgctgc acttctcaac tggtcatcag tttcagagta ggggaaggca ttttcgaatt
    13141 ctttttggta ggcgtcatca ggtccaaaag catatccttt ttctgactct cttgcggcat
    13201 ataatttgat tagatcgtca gcgatatcct cgatttttga agagactttt cgcttggttt
    13261 tcgtccattc acttccgcct agcttattga tgcgaggcgc tttggcttca gaggcgacat
    13321 atttttggat cagattcagt tgagtaacag gaataaacag tttgtcgtcg ttttgataca
    13381 aaatagtcat atagtcttgg tgaacgccat ctacttctag cgtttccatc ccaatgtatt
    13441 tcccgatacc atgattggca tggacaacgt aatctcctgc ttttaactca ttatagcttt
    13501 tcaatcgctc tgcgtttgtt actgtttgac gtctcgtttg ttttttcgtc gttttttgga
    13561 aaatttcttt ttctgtgata gctactattt tttcttgagg aagttcaaaa ccagcctgca
    13621 aagctccttc aactaattgt acctgtcctc tgatcaatgc atttttttct gtttctacta
    13681 ctaatatgtc ttcatctcga agcatttgtt ctgctttgcg tattctgtcc tttgtcggaa
    13741 taaagatcac aacagtctgt ttttgcttgc gccaacggtc catttctgtt ttcagcaatg
    13801 gcatttgtcc gaagaactgt tgcatcgtcc gatattgaaa attatggatt gcttggaaac
    13861 gaagatttcc catccctttt tggaagagtg agaaaaaggt tgtggtgaac ttttccttct
    13921 gcacgatttt ttgtatatct gctgaaaatg tctgctcaga aaacacccgc aattcgctga
    13981 ttttttgagt ctgccattct gccgcttccc tttcgatttc ccgatttgtt tccatgattc
    14041 gctgataatc atcaacgact agtaaactat ttgaagggaa ataatccaag atcgtcacag
    14101 attcttggta aagaagatct gagtagaatt ttgcttcttc tgtcgggaca cctgcttgcc
    14161 agcttgaagt cagctgaccg aagtaatctt gcaaaaactc gcggtctgct tcttctgtgg
    14221 tcgcagcaag ccgtttttct agcatttttt gcatttgctc tattccatgt tctagatcct
    14281 ctggtccgta gacttgttca ctcgttgggg aaacccagat ttcttccgtt ttttcgattg
    14341 agcgttgtgt ttctgcttca aaataccgca tagaatctat ctctacatca aatagttcta
    14401 cacgaacagg ataggttgtc gttaacgggt aaatatcgat aatgcttcct cgaatactga
    14461 attctcccgg ttttgcgacc atctcttctc gtacatagcc catcaaagtc aattggcgag
    14521 gaagattttc cacgtctatc tcatcaccaa tatgccaatt caattgcgcc tgtagccaag
    14581 ttttcttatt cggcagtcgt ttgtgcaaag atgcgactgg caacaaatag atacctgctt
    14641 ttttttcttg aagtgcgtta agcgttgcaa ctctctcgcc tcgcgcttct ggagaagaaa
    14701 aggccatttc agcagaaagc acttcatcca ctggaaataa atggatctga tcttgcggaa
    14761 tcacatgttg cagatcttct gctaactgat tcgcataata caaatttggc atcagaataa
    14821 tcatgttttt atttgttttc ttaaacgctc gagcaaatag aagtgttttc gctgagcccg
    14881 ctaatcctgt gattagttgt ctaggcattt tttcttctaa attgctgacc cattctttta
    14941 cttgcggatc ttttccgact aattgaataa tatccattcc ttttcctcct tcctcaattg
    15001 aatcgattca tcgcatccac gaacgaatgc ccttctatga gatattcgac tgctttaaca
    15061 gattgacaca tgctttcttc tatcaaaggc tgattttctt tgctgaaagg actaagcaca
    15121 tgctggacta ctgttttttt cccttctggc ctgccgattc ccaccttgat tcgatcaaag
    15181 acattcgtat tcaaatggga aataatactt ttgataccgt tatgcccgcc ggcacttccc
    15241 ttttgacgga gccggatttt tcccactgcc agatccaaat catcgtagat tacgactaat
    15301 tcctctggat aaatcccaaa ataagtcatt agtgggccga ctgcacgacc agattcattc
    15361 atgaatgttt gtggtttgac taaaaggatc ttttctccat tatgaaaaaa ttcggcaact
    15421 tctgcttcga acggattttt tttgaaagta gcttgatgct cgcgtgcaat tttatccacg
    15481 accataaagc cgatattgtg ttttgtatat tggtatttgg tacctgggtt tcctaacccg
    15541 acgatcattt tcatttttgt tttccaccta attctaaaaa gcagcacaaa aggctggact
    15601 gctaattagc ggtccagtcc atcgagcttt tttctttttt acacttgtca atgcatagta
    15661 taacacaaaa caaggcgttt cggctaaaag agaatcgtta ataaatgata aagaaattaa
    15721 aaatttcttc aaagtttaat gaaataattg atatataaaa atagtgaaat aacgcacatg
    15781 taagctttta catataatac aaccttgtta tctgttatat tttatagcca aatagcgtga
    15841 catggggctt gagaaatgtt agcataagca tgggaaaaaa caaatcaatg gaaggattga
    15901 tactaaatga ctgcagctgc agaaaaaaaa gatcatcaaa aagttattct tgttggagac
    15961 ggcgccgtag gttctagcta tgcctttgct ctagttactc aaaatatcgc tcaagaagta
    16021 ggtattgtgg atatcaatac tgctaaaact gaaggagacg caattgactt gtctcacgct
    16081 ttggcattta cttcacctaa aaaaatctat tctgctactt acgcagacgc acatgatgct
    16141 gacttagttg ttattacagc tggcgcacca caaaaaccag gtgaaactcg tttagactta
    16201 gtaaacaaaa acctaaaaat caaccgcgat gttgtcacac aaatcgttga atcaggattt
    16261 aacggtatct ttttagttgc cgctaaccca gtagatattt tgacttactc aacttggaaa
    16321 ttctcaggtt tccctaaaga acgcgtaatc ggttcaggta cctctcttga ctcagctcgt
    16381 ttccgtcaag cacttgcgga attagttgac gttgatgcac gtaacgtcca tgcttacatc
    16441 ttaggtgaac acggagattc agaattccca gtttggtcac atgcaaatgt tgccggcttg
    16501 caaatctatg aatgggtaaa aaacaaccca gaaatcgatg aagaagctat ggttaaccta
    16561 ttctttggcg tacgtgacgc tgcttacaca attatcgaga aaaaaggcgc tactttctat
    16621 ggtatcgcag tagcattagc acgtatcact cgtgccatct tagatgatga aaatgctgtt
    16681 cttcctttat cagtattcat gaatggcgaa tatggattga acgacatcta cattggtgca
    16741 cctgctgtta tcaaccgtca aggtatccaa aaagtaatcg aaattccttt aagtgacagc
    16801 gagcaagacc gtatggctgc ttctgctaag caattaaaag aaattctaga tgaagctttt
    16861 gctaaactag acgctgaata atctttgaac atgacggaaa acatctattc ggtgttttcc
    16921 gtttttttat tttatcaccc ttatggtttc taaatttttt cataaagtag agataacctt
    16981 cgtcttttcc tctaaattat gctatcatga gaccgttcca ccctaaactt ttacttaagg
    17041 agttgtcgat atgacaagat cttcgcatcg aaaaaaatcg aaacatgttg ctttgctttc
    17101 agttcttggt gttctcttag tgctgatcag cttttatacc tatcgcagta catactacac
    17161 aaagcatttt ttgccgaata cagaaataaa tggaataaat gtcagcaatc taacagtcga
    17221 aaaagcaaat gaaaaattaa aagaagctta ttctgataaa aaactggcta ttaaagaaga
    17281 tggaaaagtc tggcaggaag taccaaaatc cgagctcggc tacaaagatg atttcacttc
    17341 ggagctttct ccgatcctaa atgaacaaaa cggatggact tggggaatga cttatgtctc
    17401 agcggcagaa aaacaagaaa tagatcctgt cagtcaaaac caccaaaaac tagacactac
    17461 cgttcagaca ttgacaacta agctgactga tttgaacaaa gaccggacac ctactactga
    17521 tgcaacgatc gaaaaagcag gtgactcttt cgttatcaag cctgaagtca atggaaatac
    17581 gatcgacgtc gatgctgcgg tcaaacaatt aaaaagtgcg gtaaactctg gtaaagatac
    17641 aattgaattg actgaattca aagaaaaacc aaaagtaaca tctgaagaca gctcactgaa
    17701 agaacaactc gcatccatga atgctatcgc aaatgtaaaa gctacttaca gtataaacgg
    17761 tgagactttc cagatcccat caagtgatat tatgagttgg ctgacctaca atgatggaaa
    17821 agtcgattta gatacagaac aagtacgtca atatgtaaca gatttaggca caaagtataa
    17881 cacaagtacg aatgacacaa aatttaaaag tacaaaaaga ggagaagtta cggtcccagt
    17941 tggcacttac agttggacga tccaaacaga cagtgagaca gaagcattga aaaaagcgat
    18001 tctggcaggc caagatttta ctcgttcacc cattgtgcaa ggtggcacaa ccgctgatca
    18061 tccattgatc gaagatacgt atatcgaagt tgatctggag aaccagcata tgtggtatta
    18121 caaagacgga aaagtggccc ttgaaacaga tatcgtttcc ggaaagccaa ctacacctac
    18181 acctgctgga gtcttctatg tttggaataa agaagaagat gcaactttaa aaggaacaaa
    18241 tgacgatgga acaccttacg agagtccggt aaactactgg atgccgattg actggacagg
    18301 tgttggtatc cacgattcag actggcaacc tgaatacggt ggagacttat ggaaaacccg
    18361 cggttcacac ggctgcatca acaccccacc aagtgtaatg aaggaattat tcgggatggt
    18421 cgaaaaagga acgcctgtat tggtcttcta acaaaaataa tatataaaaa gaaagcaccc
    18481 gtacgattgg tacaggtgct ttctttttat tatctaacaa tgtgctactt acatttcagc
    18541 agcagtaaag acttctgaaa catcatcatc gtcttctagc ttatctacta gacgttccaa
    18601 ttgctctttt tgttcctcat ttaaatcaat cgtcgtttgt ggaatcatcg tcaattctgc
    18661 ttgcgccaaa gtgaactctt tttccaactc atctcgtaca gcagcaaaat cttctggtgc
    18721 agtataaatc tcgaatactt caggagaagt ttgcagatct tctgcccccg cctctaatac
    18781 atcctcaaac atcgtctctt catcaacagt caacccatcg cgttcaatag cgatatatcc
    18841 tttgcggtca aacaagtaac tgactgaacc cgtttctccc agtgatccac cgtttcgagt
    18901 aaaagctact cggacatttg tcgctgtccg attacggtta tctgtcaatg catggactaa
    18961 gattcctact ccacccggac catatccttc atacgtgatt tcatcgtaat tcgtttcatc
    19021 tacggcactc gtagcctttt taatcgcccg ttccacattg tcgttaggca tatttgcagc
    19081 ttttgctttg tccacaacaa gccgcaaagc tggattcata gatggatcag gaccgcctgc
    19141 tttagctgcc atataaattt cacgagaaag tttctgaaag actttccctc gttttgcatc
    19201 ttgggcattt tttcttcctt ggatattatg ccatttacta tgtcctgaca tgatttttcc
    19261 tcccttgttc ttttgagaat acacttctat tctagtacta tttcacaaaa aaacaaagcc
    19321 acagccaatc tataaacgct tcttgaatgc cgcaaaaagc acacataata tcacagcagt
    19381 cagagcaccg atcgaatcca acatgacatc ttggaacata ggtgttcgtc caccggtcat
    19441 catctgatgg aattcgtcca aacctgcgta ccctgttgct gaaagccaag caaggatcgc
    19501 tgtcagccac caaattttta gcttggggaa aacacctaaa aacaagctgc ctcccaaaat
    19561 aaaataggta ccgaaatgtg cgcccttcct taaaaagaac tctaaaaatt tggcgtagcc
    19621 cagatggttg atactcacca tacttccacc ataattaaaa cgtatacccg ctaatgtgtc
    19681 tttaaatggc tgattaggca gccagctttc taatcgcgaa acttgtgatt gctgtccgta
    19741 agtttgagaa gaactgtaaa ataagattat aacgactatc agtgcgatta ctaaataaat
    19801 atttccgttt ttcatttgtt tttttgaaga attcataagt cacctctgta ttttatctta
    19861 gacttttttt gaagaaacaa caatcatttt catagagact tcttccataa aaaagtgcta
    19921 tacttaattt tgtattacaa tatgaaggga gttttttcat gagttattca ttaaattgga
    19981 atctagattc tattttttcc ggaggcagtc attctgatgc tttgaaccaa cggatgaagc
    20041 aattggaaga ccaaatgaac gagtattatc accgcgtaac aaaatggtca cctagttctg
    20101 acaatgcaga gcagttaaac gctattcttc aattgcaaga aacgattacg aatggtttta
    20161 cccaatgcag cagctatatt actgcattgc tttctgccaa tgtcaatgat tcagatgcaa
    20221 aggtcttatc aggcaagctt tacgcaatgc tgcctcgtct gcaatcagcc gaaactgtat
    20281 tgtcaaagaa atttgcagaa atatctgaca atgattggaa tcagatgctt tctcaatctt
    20341 cgtttgaaac aattgctttt cgtttaaacg agattcgtcg tgatggctca caattattat
    20401 cagaagctga agaaaacatt ataaatacgc tttctttaga tggtctaaat gcttggagca
    20461 gtcattatga tacgattgta gccagcattt cgattccctt cgaacaagat ggacaagtag
    20521 tcgaattatc tgctggacaa gccttcaata agatgatggg cgatccagat ccaaaagtca
    20581 gagaaacact tttcgcagca tgggaagaag cctggaaaga aaaggcaccc ctcttcacgg
    20641 atactttgaa tcatttagat ggttttagac tttctgacta tgaacttcat ggtgtcacag
    20701 attttctaca aaaaccatta gagtacaatc ggttgaagaa agaaacattg tctgtcatgt
    20761 gggatacaat ccagaaaaac aaacaacccc ttgttaatta cttgactaga aaagctaatc
    20821 ttttcggtaa agaaaaaatg gaatggcaag atcaagatgc acctattatt ttaggcgatt
    20881 tgaaagaaaa aacctttagt tttgacgaag cagcagcatt tattatcgaa aactttaaca
    20941 aattcagtcc aaaaatggct aaatttgccc aatctgcttt tgaaaagagc tggatcgaag
    21001 cagaagatcg tcctgggaaa cgtcctggtg gttattgtac tgagttacca gaaacaaaag
    21061 aatcaaggat ctttatgacc tacagtaatt ctgttaatga ggttgcgaca cttgctcatg
    21121 aactaggaca tgctttccat agcagcacga tgtgggattt accttcttta aatcgcgaat
    21181 atgccatgaa tgtcgcagaa acagcaagta cattcgcaga attgatcgta gccgatgcta
    21241 cattaaaagt cgcaaaaaca aaagaagaaa aaatcaattt gctagataca aaactgcaaa
    21301 atgctttagc tatgttcatg aatatccatt cccgattcat ttttgaaaat cgattctatg
    21361 aagcacggca agaaggatta gtctcagaag ataagatcac agagatgatg gttgaggcgc
    21421 aaaaagaagg ctatcaagga gctttagcta cttaccatcc atatttctgg gctgcaaaat
    21481 tgcatttctt tattgatgac gtaccgtttt ataacttccc atacacattt ggctacctct
    21541 ttagtttggg catctatgct tacgccaacc aaaagggagc aaattttgaa gaagaatata
    21601 tccatttact acgcgatact gcctcaatga cgacggaaga tcttgcgaag aaacatttga
    21661 atgtcgatct tacccaacca gatttttggc aagcaggtat cgacatggtg actgaagata
    21721 tccaaacgtt catggaattg acagaagaat ttatctgatt tctattttat cacaataaaa
    21781 aaagagttag tccagaatgg gctaactctt tttg
//
LOCUS       DADVXV010000049        21265 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.050, whole genome shotgun sequence.
ACCESSION   DADVXV010000049 DADVXV010000000
VERSION     DADVXV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.050"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            145..357
                     /locus_tag="KB969_001705"
     CDS             145..357
                     /locus_tag="KB969_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6869690.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            360..572
                     /locus_tag="KB969_001706"
     CDS             360..572
                     /locus_tag="KB969_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869691.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            712..867
                     /locus_tag="KB969_001707"
     CDS             712..867
                     /locus_tag="KB969_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869692.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(864..1088)
                     /locus_tag="KB969_001708"
     CDS             complement(864..1088)
                     /locus_tag="KB969_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBB6869693.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            1166..1354
                     /locus_tag="KB969_001709"
     CDS             1166..1354
                     /locus_tag="KB969_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869694.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            1680..2015
                     /locus_tag="KB969_001710"
     CDS             1680..2015
                     /locus_tag="KB969_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869695.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            2248..3189
                     /locus_tag="KB969_001711"
     CDS             2248..3189
                     /locus_tag="KB969_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBB6869696.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            3191..4081
                     /locus_tag="KB969_001712"
     CDS             3191..4081
                     /locus_tag="KB969_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBB6869697.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            4124..4924
                     /locus_tag="KB969_001713"
     CDS             4124..4924
                     /locus_tag="KB969_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBB6869698.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            4939..5790
                     /locus_tag="KB969_001714"
     CDS             4939..5790
                     /locus_tag="KB969_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6869699.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            5991..6452
                     /locus_tag="KB969_001715"
     CDS             5991..6452
                     /locus_tag="KB969_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6869700.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            6478..6930
                     /locus_tag="KB969_001716"
     CDS             6478..6930
                     /locus_tag="KB969_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869701.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            7036..7230
                     /locus_tag="KB969_001717"
     CDS             7036..7230
                     /locus_tag="KB969_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869702.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNGFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            7261..7647
                     /locus_tag="KB969_001718"
     CDS             7261..7647
                     /locus_tag="KB969_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869703.1"
                     /translation="MKKLHQLISEKESELQNLEDSLGLGFPIVEQAKMTQISHLRLEL
                     EDLRQIEKSIQLNDNQKIVLEWLKSETILTREAPILSVNAFSDKNLLGKLPDKVRKAY
                     KLLACKQEYEVLSAFAQWGLEQEEAE"
     gene            7644..7847
                     /locus_tag="KB969_001719"
     CDS             7644..7847
                     /locus_tag="KB969_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBB6869704.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASNAIRKFGISILNDDRKWEEMR"
     gene            7844..8140
                     /locus_tag="KB969_001720"
     CDS             7844..8140
                     /locus_tag="KB969_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869705.1"
                     /translation="MKIKDGFYASSHGIGGLMLDMPIKNPKTRQKSKFKIGDMVRCKA
                     EEFIYPFRGYVEHVYNHSAIIHIENTMECDKWLAKSKDNLAVARLVDMELINDK"
     gene            8216..8632
                     /locus_tag="KB969_001721"
     CDS             8216..8632
                     /locus_tag="KB969_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6869706.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            8893..9030
                     /locus_tag="KB969_001722"
     CDS             8893..9030
                     /locus_tag="KB969_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869707.1"
                     /translation="MDKEIKVTVKLDLTELKELLNKASDQVEQLQETLDEIANFKIQV
                     S"
     gene            9440..9670
                     /locus_tag="KB969_001723"
     CDS             9440..9670
                     /locus_tag="KB969_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869708.1"
                     /translation="MRNYWYISLTNEYPRTIDDCSVRVVRSVQIKKKYSIVEMTREAT
                     PKEIDKCKLLYCGHGFYDEPNIQNNINKNLRD"
     gene            9829..10662
                     /locus_tag="KB969_001724"
     CDS             9829..10662
                     /locus_tag="KB969_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBB6869709.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELKSNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPKRNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            10655..12070
                     /locus_tag="KB969_001725"
     CDS             10655..12070
                     /locus_tag="KB969_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBB6869710.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPENMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTTVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            12082..13611
                     /locus_tag="KB969_001726"
     CDS             12082..13611
                     /locus_tag="KB969_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6869711.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEYMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKDPTAKAEYVTKKLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            13529..14581
                     /locus_tag="KB969_001727"
     CDS             13529..14581
                     /locus_tag="KB969_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBB6869712.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            14583..14900
                     /locus_tag="KB969_001728"
     CDS             14583..14900
                     /locus_tag="KB969_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869713.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            15027..15650
                     /locus_tag="KB969_001729"
     CDS             15027..15650
                     /locus_tag="KB969_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBB6869714.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            15665..16555
                     /locus_tag="KB969_001730"
     CDS             15665..16555
                     /locus_tag="KB969_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBB6869715.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            16578..16793
                     /locus_tag="KB969_001731"
     CDS             16578..16793
                     /locus_tag="KB969_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869716.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            16805..17146
                     /locus_tag="KB969_001732"
     CDS             16805..17146
                     /locus_tag="KB969_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869717.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            17146..17517
                     /locus_tag="KB969_001733"
     CDS             17146..17517
                     /locus_tag="KB969_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869718.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            17510..17905
                     /locus_tag="KB969_001734"
     CDS             17510..17905
                     /locus_tag="KB969_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBB6869719.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            17907..18284
                     /locus_tag="KB969_001735"
     CDS             17907..18284
                     /locus_tag="KB969_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869720.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            18285..18893
                     /locus_tag="KB969_001736"
     CDS             18285..18893
                     /locus_tag="KB969_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6869721.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            18893..19234
                     /locus_tag="KB969_001737"
     CDS             18893..19234
                     /locus_tag="KB969_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869722.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGPVVEEAAEVMEG
                     MQNAVDGKSVSEALSRAYSFIADILFEGQFTGEDYRQGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            19476..>21265
                     /locus_tag="KB969_001738"
     CDS             19476..>21265
                     /locus_tag="KB969_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBB6869723.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIK"
BASE COUNT         7744 a         3090 c         4483 g         5948 t
ORIGIN      
        1 aataaactaa tagtctcccc agacatcagt aagctcgctt tttgtgcgct gtattttgta
       61 tgcttacata atagcatatt tgcagttttt gtcaaactta ttagacaaaa atattagaaa
      121 atattcgata agggggtatg aagcatgact ttaaaacagc aagtattaat tgctttagta
      181 aagaaaggtt ggagtcaaag agagttagct cgacgaatgg gtatatcaat tacttattta
      241 cgagatatct tcatcgaaaa aagaaaacct aaggaacgtt taaaacaaat cgaagaactt
      301 ttggatatca agttagaagt agattctaat gatcagccat cagaacagga ggcgtaaaaa
      361 tggtacaacg tttgagcaaa gcggagttta aagagaaata taagtattct gaaagtactt
      421 atcaaagaag aatgaaggaa tttaaaaaat cacgttttag tgaggggtat aacgcagtta
      481 cttccaaaga aataacaatt gatgtcgatt tatatgaaca gtttagaaca tggcgttcta
      541 aaaatcgatt tagagttaga gctgtttgtt aatagctaaa aaatctaaat tcaccacttc
      601 tgaaaagagg agttgctgct ctcctttcaa gtttgccaaa gtccacgttt tttcattttg
      661 gcaactcctc ttcttggagg tggtgacggc gagagacgaa ggagggatga catgaaggaa
      721 gaatcaaaaa tagggatttt gaatgagaac aattacacaa gattaattat tgaaacagaa
      781 gaagggaaaa aagtagcaga agttacattg accgatgcaa ctcctgctga cggttatcgt
      841 attcgattaa ctcctaaata tgattaacct tttggtgggt gtggatcgtt tccgtgacta
      901 tcacggcttt gaatttttcc atctctgcca tgaataaata gctcagatcc ttgattttta
      961 gaaatctctc tagcgatttt tactgcttct gattttgtat tagtatgtgc agtcgcttta
     1021 gaatttccag cacctttgac attccaacca ccattggaat taggtacaac atgttgattt
     1081 tttcccatag ttttcacctc catttctata gaaatatttt atcaaataga aatggagaaa
     1141 ttcaataaac gaaaggagaa gtgatatggc atataccttg caacaagaac atcaaattct
     1201 cggtttgatt aaacaacgca ggaaacaatt acaagatgac cgtgcagcgc ttagaaaagc
     1261 cgatgagcta tcagataggc aagctgaact aattgcttct gaacttgagg atttgagaat
     1321 gctagaaata aaaaataggg agattagatt atgaagaaga cagacacact ttttatagga
     1381 ttcattttgg ggttattagt gattgtagcg caccaaagta ttatcggggg aagcttgttc
     1441 gcagcattga tggttttaat caatctgctt gattcaaaag aaaggagcaa ctatggcacg
     1501 agaagaagcg ctaaaaatcg gtaaagtgat tgctgataat cggtggggaa atagccgccc
     1561 tattatttta agcaagcaac atatcgaaaa gcaaaaagca tggcaacaaa taaaaaagtg
     1621 actctgccag ccagcaaaga gtcacataca aatttataaa actaggagaa ttatatcaca
     1681 tgaataagaa aattgaaaat cttatcgaag aattgaaacg tgaatgccaa aagcaaggtg
     1741 tttctattat ttgtacagcc caaaaagaag gggaacttaa aagtctcgtt tatggtgaga
     1801 caacagaaat tttactttgt cttgctatgc aagaagaaca tttagatgaa aatctcccat
     1861 tgtcagcaca tattatgcgt agaattgctg tggatgctta cgaacaagcg aaaaatgaag
     1921 aagaaaatca accttcaaat catacttttg ttattaataa caaggaagat ttagctgatg
     1981 tgatgactcg tattctcaag ggggaatttc aatgatgaat gaaaaaacaa ttgatctact
     2041 cattatttta tttttcacgt tagtgattgt agcgaaaagt tatgtaatct ttggcttgtt
     2101 attcgcaatt accatgcttg tgctttgcgt gttagcaagc agaaaagagg ttaaacatga
     2161 acgagttagc aaatcttgac aactatttaa ctgatcctga ttatgctaaa ccaccatatg
     2221 aagcaccaat tgatgaggag gatgaagatg agtaaatcta ccttagaaat gagccatcaa
     2281 gaatggcttg aagaccgtaa gaaaggcatc ggaggttcgg atgttggaac aattttagga
     2341 ttgaataaat ggaaatctcc ttatcaacta tggctagaaa aaacaggaca agtagtactt
     2401 gaagaatcag gaagtgagcc cgcttattgg ggtaatgttt tagaagaagt ggttgctaaa
     2461 gagtttcagg aacgtacagg caaaaaagta cgcagaagaa accaagtatt tgaacatcca
     2521 ttacatccat ttttaagagc aaatattgat cgggaagtag tgggagaaaa tgccattctg
     2581 gaatgcaaaa cagctaatca atttctcggt aaagaatggg aaggcgaaga ggtaccgctt
     2641 agctatctct gtcaagttca acattacatg aacgttctaa acaaagacta ttgttacatc
     2701 gctgtcttaa tcggtggtca aaaatttatc tggaagcgga ttgaacgaga tcaagagctg
     2761 atcgatacaa tcactgaaca attagtagag ttttgggaaa caaacgttct tggaggtatc
     2821 gagccaatta ttgatggtag tcaagcgaca gctgatttct tgaaagagaa gtatgcagat
     2881 gttgaagacg ttcaaacgac gttaccaatt catttcgatg aactagttga acagaaaaac
     2941 gaactcaaac ggactaagaa agaaattgaa tcagctatcc gtcaagtaga caacgagatt
     3001 atcagcgagc taggtaaacg tgaagccagt atcggtatca ctcaaaaaaa catcatcagt
     3061 tggaaatttg tccgtacgag acgtatgaac tcgaagaaac tagcagagaa atatccagat
     3121 gtcgcaaatg atgaagagat ttataacgtt actgaatcaa gaaggctaac cgaaagggag
     3181 atcaaataat atggcaacaa atgaatcgtt aaaaaatcaa ttggcagcaa agccacagaa
     3241 acaagttgca ccaggtcaat taggacttaa agctttgatg aatacaccaa caatgagaaa
     3301 gaagttcgaa gaggtgcttc atgacaatgc taatgctttt atgtcgaatg ttatgactct
     3361 tgtatctaat gacagttatc ttgcagatag tgaaccgatg tctatcatga gtggtgcgtt
     3421 aactgctgca acattaaatc ttgggctaga taagaattta ggttatgcat atttagttcc
     3481 attcaatagt aaaaacaagc aaacaggaaa atgggaaaag aaagctcaat tcatgcttgg
     3541 ctataaagga tatatccaat tagcccaacg atcaggtaaa tacaaagcat taaatgtgat
     3601 cgaagtttac gaaggagaac taaaaagctg gaaccgactg acagaagagt ttgagtttga
     3661 tccaaatggt agaacgtctg atgaagtcat tggatatgtt ggctatttcg agttactgaa
     3721 tggattcaaa aaaactgtct attggaccaa acaagaaatc gaagctcatc ggattgctaa
     3781 caataaagat cgcgataaga caaagttaag tggtgtgtgg gcatctgatt acaatgcaat
     3841 ggcacgaaaa actgttttga gaaatcttct ttctaaatgg ggaatcttgt ccatcgaaat
     3901 gcaagaagcc accacatcgg atgagagagt ccaaagggtt caagaagacg gcagcattat
     3961 tgctgaaaca gaagttgaag aagatattcc tgaaagaaaa gaagcagagg ttatatctga
     4021 agaaaatgaa gatgtacaaa ctggattatt tgatgcatct aatccgccgt taaacaaata
     4081 atgagggagc tttctccctt gcttttctag aggagaaata cgaatgaaca caggatatgt
     4141 caaattacat cgaaaagtga tgaattcatt cgtttggacc aatccttata tgtataaatt
     4201 atggaacttg tgtttgatga aagcgagtca tgagaatcgc aagatacttt ttaatggaaa
     4261 agagatacaa gtgaacagcg gagaattcgt cacagggcgc gatgctatca catctgagat
     4321 gaacgaaggc gtgaaacgtg aacatcaagt gaacagcggt tctgtatgga gatggctaaa
     4381 acaatttgaa aaaaacggaa tgttgaacat caaatcaact acgaaataca gcgttatatc
     4441 aataaaaaac tggtctttgt accaaagcag tgaacaacaa atgaacatca aacgcacaac
     4501 aagtgaacaa caagtgcaca caaacaagaa tgaaaagaat tataagaatg aaaagaataa
     4561 taaaacatca tcgtcgcaac cacgcaaaaa gcgtgtttac gacaccgact cagtttacta
     4621 cattctcgcg gaggagttat tcaaacagat ttgtcagaat caggaaatca aaaagccgaa
     4681 tctgcaaagt tgggcagata acattcggaa aatgatcgag atcgacaagc ggaccgaaaa
     4741 ccaggtacgg ggaatgattg aatggagtca gcacaatgtg ttttgggcat cgaatatttt
     4801 atctgctaaa aaattgcgag aaaaatacga cacaatggca gcgcaagcca atcgtgatta
     4861 taaaacaaaa caaactaaaa cgcttgaata cgagaaattt agcacagatg agttgcctat
     4921 ttgagaggag gcgtaggcat ggaaactgtt ggggaaatca tggaaaagct gatacagaaa
     4981 gtgcttgtcc aacgtggcga atgtcctgaa tgcggacagc ctttgtatgg atggcgtacg
     5041 aagaaccctg atggctcaga acgttgtaag ccaacctgta tgcaatgtgg gtataaagca
     5101 ttgcgagttc aggaagactt acaaacagaa cgaatttaca acgagagcct gaaagcaaga
     5161 gcaatcaatt ttttcaaagg tggttctgtt gtgcctaatc aagcgttgtt tgattgcaca
     5221 ttgcagaatt atcaaattgt cgatcaagaa acaagacaag cggttgaagt aaccaaacgc
     5281 tttgttaatt cagtcttgtt aggaaatcca agtcaccttg ttttaactgg aaaacaagga
     5341 acaggtaaaa gtcacctagc gatggcagcg gcttgggaag tcttgaagcg atcaaactac
     5401 gataaaaaaa tcttatttat cgggttacag gaaatgctgg atcaaatcaa attttcgtac
     5461 aacaatcctg aactcagaaa aacgattgag ggatcgttga ttgcagatat caaaacagcg
     5521 gatttagtca tcattgatga tatcggttca gaactaggaa aagatgcatc agatagtcga
     5581 gcgtttggca taaacacgct aaattcgttc ttggatgcac gacagaacct agcaacgatt
     5641 atcacaacga acttgcttgg tgaagaactg aaaaaagctt acggtacgag aacaatatca
     5701 agaatgtttg tcaactctga tggatttacg atggtatttt ctcaaacagc agacaagcgc
     5761 ataaaaccag tcaaaggagc gatcgcatga atttgactaa acaagaaaaa agaatctgtc
     5821 gtcagataat gttgcaaatt ataggtgatc gtgacatgga cgaattatct caacaagaga
     5881 gtcgaatggt tcggaagata agtaagctaa ttatttatcg ggatacagaa agatttctca
     5941 ctgttttagg taacgtctac gagaatccag agttattgga ggtagagtaa ttgccaaaaa
     6001 tattagatgc atgttgcggt agtagattgt tctggtttga taagaacaat tctgacgtaa
     6061 catttatgga ttgtcgtcag cagtatgaag aattatcaac aggtcatgtg atcaatgttg
     6121 atccagatgt ggtcgcagac tttcgcgata tgccttttga agatgatgtg ttcgatatgg
     6181 ttgtatttga cccgccacac ttaagacatg tcggcgaaaa ctcatggctt gccaaaaaat
     6241 atggaaaatt agacgaactt tggccagaag acatcaggca aggttttgca gagtgtatgc
     6301 gagttttacg accttcagga acattaattt ttaagtggaa cgaggaacag ataccacttt
     6361 ctgatgtgtt agaggctatt ggagaacagc cattgtttgg taataaacga agcaaaacac
     6421 attggcttgt gtttatgaaa aaattcagct aacggaggaa acaaaggagg aaaagtaatg
     6481 aagattgtat taaataaatg ttttggtggc tttgggttga gccatgaagc aaaaatggaa
     6541 atttttaaaa gaaaaaatat tgaagtattc ccatacatca ataactttag ctatgactca
     6601 gatgatgaat acacgagata cacaggccaa aagctaggtt cgatggattt tatctactat
     6661 ttcaaaaaag acccgaaaat cgacaaagtt acaggaattt atagcgaaat tgaccgactg
     6721 tacggaattg ctgatgattc cagtttttca agtgattcaa acagaggtga taaggacctc
     6781 gttgctgttg tcgaaaaact aggaagtgag gccagtggac catatgcaag tcttaaagtc
     6841 gttgatatac ccgatggggc tgagtgggaa ataagtgatt atgacggcgt tgaaactgca
     6901 cattatggtt ttcaaacagg tagtatttag tccactaatg acaactaaag aggaggcaga
     6961 aggatgagtg aagatgaata ctttgaacag tagtctatta acgacagaga tttttaactg
     7021 gaaaggggtg tagtcatgga cgcatcggaa gtagtaaata aaattaatag tctcaaagag
     7081 gttttcggag acgtcgaagt agtgataaac gcacaaggct atgacaacgg attttttaag
     7141 cagattaccg acattagcat tcagcaagga atggaagacg aagatggaaa ctttatcgat
     7201 gaagtagcca ttttagtgac ttgcgagtaa gtaattgaca gctaaagagg aggcagaagg
     7261 atgaaaaaat tgcaccaact catatctgag aaagaaagcg aactccaaaa tttagaagat
     7321 agtttgggat tggggtttcc aattgttgag caagctaaaa tgactcaaat cagtcatcta
     7381 cgacttgaat tggaagattt aagacaaata gaaaaatcaa ttcaactcaa cgacaaccag
     7441 aaaatcgtgt tggagtggtt gaaaagcgag acaattttaa ctagagaagc accaatatta
     7501 tctgttaatg ctttttctga taaaaattta ctaggaaaat tacctgataa agtacgcaaa
     7561 gcttataaac tattggcttg taaacaagaa tatgaagtcc tatcagcatt cgctcaatgg
     7621 ggattagaac aggaggaagc ggaatgaaca acagacatcg cagaataaca aaactaagaa
     7681 aacaggaact gaatgtacta aagacaaagt ttgaaaaaga atatggaatt tcagcagaag
     7741 aaacatataa agtggcaagt cagtttgttg ctgatgcgag taatgctatt cgtaagtttg
     7801 ggatttcgat attaaatgat gatcgtaaat gggaggaaat gagatgaaaa taaaagacgg
     7861 attttacgct agtagtcatg gtatcggcgg tttaatgcta gacatgccga taaagaaccc
     7921 taaaacacgt cagaaatcaa aattcaaaat cggtgacatg gtccgatgta aagcagaaga
     7981 gttcatctat ccgtttcgtg gatatgtaga gcatgtctat aatcattcag caatcattca
     8041 cattgaaaac acgatggaat gcgataagtg gttagcgaaa agcaaagata atttagcagt
     8101 ggctcgtttg gtggatatgg aactaatcaa tgacaaataa aaaagccgga tcgctccgac
     8161 tgattcaata aatccaacac atttattata tcacataaag gagcggtttg acttgatgca
     8221 attgttacga gaggtagatt tcaaacagac aagatgtaat gcgagagatg tgctgaagaa
     8281 ctttcggcgt ttggagcgga tggcaggtcg ctctttgata gatattaagt cgccgattat
     8341 tacggatatg ccgaaggcac cgaagcacgg caataaggca gaagacgcga tcattcagat
     8401 gatggatata gaagcggaga gagacgcaat actagcggct ttgatggctc ttagtctgat
     8461 tagccgtcag atactctact acagcttctg tgacgtaaac aagcactcta attatgaaat
     8521 agggcaattg atacgaggat acggagagaa gaatgtagag aagttgaaat ccatcgcatt
     8581 aatcgaattt gcagaagcat acaaaaaagg cgtgttagtt cagtatcgtt gattttgtag
     8641 ggtttttgta gggatagtgt agggtttttg agcggtttaa cgtgatatta tggtagtgtc
     8701 gaaagattag tgataggtct gagacaaaat aaaatgtaag ggaggaaatc tccctcatcg
     8761 ttttaactta agcttcgata gacagcaacg gaaatattaa gaataaggat gtgaatttca
     8821 actccttcta aattgttctt attatctatc atccgttgtt gtctattaat ttatgcatcg
     8881 gaggaaaaac gaatggataa agaaatcaaa gtaactgtca aattagattt gactgaacta
     8941 aaagaactgc tcaacaaggc tagtgaccaa gtcgaacagt tacaagaaac tttagatgaa
     9001 attgctaatt ttaaaatcca agtttcttag cagtatattt tttagcagct gcactcataa
     9061 aatcatacca agtatcagaa aaatataact taactaaata attaaaaaag gtgggtaaat
     9121 agaaatgacg gcgttaataa tttcaatttt tgcgctctgt cttaatgtct atatgattgg
     9181 atttaaaaat ggacaaaata aaaaatagta gcagccgaga ataattttat agtgtcactg
     9241 tggcggaaat agaagacgca aaggtggagg taggaagcgt atggcgcact atcgggacct
     9301 tgtacaaaac tagaaaggac tagtacgtgt gtggtgcgag ccctagggag gaacaggata
     9361 accgcctgtg tgtaggttgc tattacatat tagatcactc tttgagtggt ctttttattt
     9421 acataaagga ggctacataa tgagaaacta ctggtatata tcgctaacta atgaatatcc
     9481 tcgaaccatt gatgattgtt cagtgcgtgt tgtgcgttct gtccaaatca aaaagaagta
     9541 ctccattgtt gaaatgacca gagaagctac gccaaaagag attgataaat gcaaacttct
     9601 ttattgcggt catggtttct atgatgaacc aaacattcaa aataatatta acaagaattt
     9661 gagggattag aatgcaagaa atggcttaaa aatctccaat caggacaaat caagttagac
     9721 aaagtttccg atttaaagat attgattgaa gctgatttaa tgctaaaaga tattgaaaat
     9781 tagaaaacaa aactcaacct aagaagattg cgaggtggtg tgtattgaat ggcaagacaa
     9841 cgtgatccaa gacgtgatga agccaaaaga atttggttag aatccaacgg agaaaagcag
     9901 ttaaaggaaa ttgcatctga attaaatgtt tcagattctc aggttagaaa atggaaatcg
     9961 caagacaaat ggagcgctga attgaaaagt aacgttacca atggcaaaag taacgttact
    10021 aatcaaggtg gcgctcctat tggtaatcaa aatgctaaag gtaacaaagg aaacagcaga
    10081 gcatcaccgc caaagagaaa taagaatgct cttaaaactg gtgagtatga aacaatattt
    10141 tttgacacgt taaccgataa tgagaaggac atctattcta gtttgaatga tgatccttct
    10201 tttgctttgt ccgaagaaat acgacttctt aaaataagac aacttcgaat gatgaaaaga
    10261 atccaacaag ctgaagctgg actaaatgat gaagaagtcg aacgattgca gcagctaaga
    10321 aagattaaaa ctccgattga aaaaaatggt aaaaagctag aaatcaagcg tgaggttatg
    10381 caagatgtgc agattagcag aaaaaaacat cgcaaaattg atgatattct ttcaattgaa
    10441 gattcattga ctcggattag caaccagtta gctaaagcca tcaagcaaat gaatgaactt
    10501 tatatgaatg aatacagaac tgatttaatt aaagctcaga ctgataagat ccaagctgag
    10561 acaaatgaaa ttggcggaaa taattcaggt gaagaaatag aagaatggaa acaggcagtt
    10621 ttaaatgccg caaacaaacg ggcggtgaaa gaaaatgaat aatgaattta ttccttttgc
    10681 tgatattggt tctgccattg attattacta tgataaacca gtagcttttt gccaagatat
    10741 tttgcatttg aatcctgatg aatggcaaga aaatgtttta aatgatttag ctgaattttc
    10801 aaaggtttct gttcgttctg gtcaaggagt tggaaaaaca gcattagaag caggagcaat
    10861 actttggttc ttaacgtgtc gaccctacgc taaagtaata gcaacagctc cgacaatgaa
    10921 gcaactttac gatgtacttt gggcagaggt agctaaatgg ttaaatgata gcttgatcaa
    10981 aaacttactg aagtggacaa agaccaaaat ttatatggtt ggtgattcag agcgttggtt
    11041 tgctacggct agaacagcga ctaaaccaga aaatatgcaa ggttttcacg aggaccatat
    11101 gttgattgtg gtagatgaag cttctggtgt gtctgatcca attatggaag ctattcttgg
    11161 tacgctatca ggttttgata ataagctgtt gatgtgtgga aaccctaata atattgaagg
    11221 tgtcttttac gattcccaca attcagaccg tgataaatac agagttcata aagtatcaag
    11281 ctatgatagt aaacgtacaa acaaagacaa tatagaaatg attcttaaaa aatatggaaa
    11341 agaaagtgat gttgctcgtg tccgtatttt tggagaattt cccaaaggtg cgttggattc
    11401 atttatcagt cttgaaacgg ttgaattggc tacagaaaaa caaattagtg attctttagt
    11461 caataaaaca acggttgctc atattggtgt tgacgtagct cgatatggtg atgattctac
    11521 gattctcttt cctagaattg ctaccagggc attggagtat gagaagtatt caaaacgtag
    11581 cactatggaa acaacaggat atgtcatcaa catggccaag aatctaatga gtcaatatcc
    11641 gagtattgat aaagtgatga ttaaagtcga tgacactggt gtcggaggtg gtgtaaccga
    11701 ccgcctagaa gaacttatag aagacaagca ttatcctttt gaggtgtttg gagtgaataa
    11761 cggttcaaca tcagaagacg atttttacga taatttaggt actcaactat ggggaaacat
    11821 caaggaaatg ttagaagaaa atatgacagc aaatcttaac ggagaacagc ctgttattga
    11881 attgccttct gatagttcgt taatcaaaga attaagtact cgcaaattca aaatgacaag
    11941 tagaagtcgt atacgtttag aaagtaaaga tgatatgaaa aagcgaaata ttggtagtcc
    12001 cgatattgct gacgcactgg ctttagcgtt ttatgagcca ccaagtcact atcaatttat
    12061 tcaattttag gaggtgagtt tttgattagt acagtattat ctttagagag atataagaag
    12121 ctacgtgtta aatatgcaac acaaattgaa gatggaatgt ttgatccgaa tggttttata
    12181 gaatatatga aaccattttt tgctgatcgc gaaagaaaat atctagctta tactagcgaa
    12241 aagaatgaaa tagacaatag accaaagcct aacactgata ttgtaaaagt taataataaa
    12301 cttcatgctg gtatgtattc aattgtcgta gaccaagcag tcaatcattt tactggtata
    12361 cctatcaaat gggattacga tgtatcggaa caaaaaagaa cactcattca aagattaaaa
    12421 gataaattct taaaaaatga tatagaactt ccaacagttc cagaagcttt taacaaatta
    12481 acaagcaatc ttgattccat gagattcgca atgcttgatt ctgaaactgc aacttttcaa
    12541 ggagcttgtg gagtagcttt ccgattgtta gagcctgtgg aagaagatga tggttggaag
    12601 ttaagagcaa gtaatattga accttggaga gcagaaagat atggaaatgc cggaatctat
    12661 atcaaagaaa agtatgactc ttaccagaaa aaattttttc aagaaatgaa agttatgaca
    12721 agaaataaaa ttctgacata tgcttgctat ggtgatttga attttgttac aagcggaacg
    12781 ttcaaaaaaa ttgatgagac cgataaccct ttggggacga ttaccttggc agaatttaaa
    12841 aataatacga atcgttattg tgattttgaa gtagctgagg aaattggaga tgcaattgat
    12901 cgtgctttgt ctgatcaaca aaacgaaatc gaacaattta agcttgcgta catgcttgtt
    12961 actggcacaa caatgagcaa aggcactgct aaagaaatga tgaatcagct agggattatc
    13021 aacttaaaag accctactgc aaaagctgaa tatgtcacaa aaaaattagc aaaagatttc
    13081 aatgaatatc atatggatct attgaaaaaa cagttttaca ccatttgtaa agcaatcgat
    13141 tttaacgatg aggtgtttaa atcaaacagt tctggagaag ctcgcaagtg gcaaatcatt
    13201 agcctagaag cgaaaacaaa tactaaagag caatatttta gagaaggatt gaaagaatgc
    13261 gcagaaacaa ttgctgcttt tcttaagttt catgacaaag tagaaattga gcctgaaaaa
    13321 attattttta ctttctctag atctttgcca actgatttaa gttatttagc tgaagcttta
    13381 cctaaacttg caccatacgt atccaaacga actattcaga gccaaattcc atttgtaaca
    13441 gatgttgatt atgaaaatga aatgatggaa ttggaaagtg gaagtgctta tccagatagt
    13501 gaatacaatt ttggcggagg tggcaatagt gacgatagaa acgaagtatt ggaccaaacg
    13561 tcgagaactg gaggatcaag caaggctcaa acaagaaaat cagacactta aaaaattaac
    13621 tagtgtattt cctgaagcac tgaaagagat acaagcaaaa ctattatcac aagctgactt
    13681 acacaatatc acttatccag aaatgatgga gttttacagt acaagtaatc agaaaaaata
    13741 tcgtgaatat gtggaaaaaa attataagtc attaaaaatg tatgatgcaa aatacaaaga
    13801 gtttatcgat gaattttttc caccatttga ctatgcaaaa gtcaatcgct tattacaaat
    13861 acgatcagat gtatttaaaa ttcttgcaga atatgcgatg gatgcagatg tgaatcaata
    13921 tttttctgat cgcttagagg aaattcttca aagaacatat tcttctaatg ctaatgtttt
    13981 tgttcaactt ttaaacgttg atataccaaa ttatttacca gaaaatgaaa ttaaacatta
    14041 tttgaactat ccatggtcag gaaagacatt ttcaagaaga ctttggggaa atatttcatc
    14101 gcttgaacag aaactctcta atgctattgt aaaaagtgtt gctagtggag aaggcgttat
    14161 acacgcatta aacaccatga gattagactc agaaatttgt gacatgttta agttagaaga
    14221 atcaaagtat aacaaagcga tagaaaatct cgttcgaacg gagtatgcaa aatttgcaca
    14281 agatggtatt gaaaaatcat atttagaaac aggtattgag gaatacaacg tattgactgc
    14341 aaaagatgag agagtttgcc ggatttgtgg aggaaaggca agtaagaatc cctataaact
    14401 gaaagatgct gtcataggtg aaaatcgagc acctttccat agtcgttgta gatgtacgga
    14461 tgttcctaat ttaccaaaat taggaaagga tattgatgaa gaatatgacc gtttatttgg
    14521 cgatttatta gatgagtttg cacatgattc ttttggaatt aatttgaaac ggaggaagta
    14581 gaatgaaaga tttttttgaa gcagtactaa caattaatgt aaatgctgat attgcagaag
    14641 cctacaaaac agctattgag tctgagaacc atcctaatgg cttgagagac cattggaatg
    14701 gcaattatgc ctacgtggtt attggcgatc aaactgttaa ttatcaagat aatactccag
    14761 ttgataagaa taccgttaat ttaacgattc aattattatc tcattcatta ccaaatttaa
    14821 aagaaacagt tgattggtat gaaaagatgg gatgtattgt tgttagaact gactacaaag
    14881 aaggaaagtc tagtaattag gcttttttat tttgtccgaa atgacgttaa actagcgcaa
    14941 tactgggctt ggttgaatgg tggggcgcaa ctattaaaac tcaaagcaat gcggggcgtg
    15001 aaaacgaatc gtggggcgaa aggagaatga gcatgaaaca caaatcatta atgccaatga
    15061 atttgcaata ctttgccgaa ggtgacgatc aaaagttttc ttttgatgac ttcaaatctt
    15121 ttgtggaatc caatgaagaa gctcaaaaat ttattcagtc acaatctcaa agtgttgccg
    15181 acaaacaatt ggaagcttgg aaacaaaata acttagataa aattaaacag gataccatca
    15241 aggaatatga ggaatctaag aaaaacaagt cacctgagca aattcaactg gaaaaactac
    15301 aagctgaatt tgaagcagaa aaagcgttgc gtgtgacaag tgataataaa gcatttgttg
    15361 cagaacaaat tgctggatta gaactagatg gagagttaaa agagtctatt tctcaattta
    15421 tgctaaataa tcttgttagt tcggatacag atttcactaa gaatgctgtt gaaggtttta
    15481 caagtgtttt gaatgcaatt aatgagaaac atgcagatgc attaaaagaa ctacaaatga
    15541 agtctgcatt tggtggaact caacaatcga ataaccaggt tcagcagaac aatgaaacat
    15601 taacaaatcc agaagaacaa ttaggacaaa ttcttcaaca atttaactag gagagtgaaa
    15661 aattatgaaa aaaacatctt taaataattt agagtatttg gatatttcac cagcgattaa
    15721 tgctatgcaa gtaccaaata cacctttttt aagctattta cttggtgctg gaaaaacaga
    15781 gccagcaaac tcgacagaaa ttaaatggcg tgaatatgat atcaacaacg atgattcttc
    15841 tgaaaaactt gagggcggag aatatccaga tgctgaatca ggtcgaactt ggtttaacaa
    15901 ctatactgaa atttttagaa aatcaacctc tgtatctggt acattagatg ctattaatgt
    15961 gaatggagtc ggaaatgaat taactaatca agtagcacta cgtggtatgg aaatgaaaat
    16021 tgatttgaac cgaaaattga ttactggtgt aaaagctgat gaaaatggtt ctaaaggtcg
    16081 tcgaatgaat gggattttga acttgatcaa ttcagcaaat aaggcagaaa cagccactgc
    16141 gggtgcagta acaagaaaag atatcgatac tttatttaaa ttgatgtatg aaaaaggtta
    16201 tatgggagaa aaactatgct tgatttctcc agatatgcag gagttaatga ctgatgagtt
    16261 agatggaaaa tcaacaaaaa ttgttcagtt cggggaaaga gtaacttttg gattgcaaat
    16321 tggaaatatc gtgtctaatt acggtacagg tattgctcta ctagaaccat cattgccaaa
    16381 aggaacaatt gccgcaatcg atactaatta tgtgaaacta cgtccattac gtgaatggag
    16441 agcagaagaa cttgcaaaaa caacggattc tagacgtatc ggtcttgtag gtgaatactc
    16501 tcttgaatac aatgcttcaa actctggggc aattttaaat ttaaagtctg aataaaaggg
    16561 agttagtact cccttttttg ataggaggaa ttacagtggt aaaaaaagat gaaactaaaa
    16621 aagatgaagt cgtgaaatat agagtaggta aaactaaaaa ttttgttggg tttgttcatc
    16681 ctaaaactcg tagatttatc acagcagatt caaataacga atttatcatt tctatagatg
    16741 ataaagaagc aattgcaatt ttggaagatg caattgatgt taatgaaatt taggaagtga
    16801 tctgatggat gaatcgctaa aaacggaaat cattgagtct acaaaagaag attttccaga
    16861 tttgagtgaa gaacgcataa ctaatttatt agaaataatt ttgctagaaa ttgaatcata
    16921 caacacttgt aaaaatgata tttcatggga aaagttaaaa agcgtgatta gtgaagtgtt
    16981 gtataaaata ataaaaaatg aatcagaaaa aacagtatct tcagttagac gtggcgatac
    17041 aacgattagt tatgcttcaa caacaaatga tgttagtgag ttacttctag gctatggtga
    17101 tttgatacga agagttattg gttgtggagg attggagttt ttttaatgaa tgaagcagat
    17161 attttagaaa ctacttatga agatagttgt attattgaaa gactgacgga cattgaagat
    17221 tctaatacaa atattactat tcaagattac aaaaaagtat atgataatcc tatttcttgc
    17281 gctctttcac aaggtcaaat cgatggacta gcagtcatag aagatggaga gatggtaaat
    17341 gtttcaactg acacatataa attatttgtt catcctaaga ttaaactaaa aaaaggagat
    17401 cgaataacaa taactcaaaa ggccagtggc ttaatttttt ctctatttgc tactaagcct
    17461 ttttactatc ctagtcattg tgaagtgaat ttgataggaa gtgagaaaaa tgggtaatct
    17521 caaatatgaa tcaaatgcag aaaagatcat tgagaatttt aaaaatatga ctgtaattgc
    17581 tcaaaaagaa ggaatatcct tcgttaacga ttcaatgaat aaagtcgtta gtttagctaa
    17641 accattaact cctgtaaaat caggtaattt aaggcgagga tatcgtgtag taaaagctag
    17701 aaaactatca agcggtcgaa ttgttggagc agttataaac aatgaacatt attttaaata
    17761 tgtagaagaa ggtcatagga ctaaaaatgg tggctttgtc aaagggaaat tcatgttaac
    17821 tcgtgcaacg aatcttgcaa atatgtctta tattcctcga agatttaaac aaatggcaat
    17881 aaaaatcgtt aagaaaggaa agtaacatga aagatgaaat cattgctgca atcagtagca
    17941 aattaaaaga aatctatcct gatgggacaa tatatcttga ttcagttatg cagtcaacta
    18001 aagattttta tttcgtttta tcagtaatgg aatctggaac tgaaaatgta ggaattgata
    18061 ttcaaaatgt ttctttctta attgatattg cattgattga taataaacct aatagaaatt
    18121 taattaatga attagtctca cgttgtggga ctttttttaa tacgattaca atcgatgagc
    18181 aaatattatt tccaaaagcc tatttacctg atgaagcaga tggtgttcaa catattcgtt
    18241 ttacattaga atttccacaa tatattgaat ggagtgaaag ataaatggga gaaaaaagaa
    18301 gtaaaaccgg aattatttct gtcgaaaaac ctacttggtt tcctttggaa gatgagacag
    18361 ggaattttcc ggtatatggt actgcgttgc caatgggaac agcagtaagt atcaaaccaa
    18421 cagctaatta tgaaacaaca caagattatg gggattcagt ggttcaagat caatttacag
    18481 cttttggtgg tgcagaagtt gaactggaag caaatggata tactcataaa gttttatcta
    18541 caattactgg agggaaaatt gttaaaggtg gtgccttgcg ttctggagaa gatattgcgc
    18601 aagatggtgc gtttgcatat agacgtaaaa aatcgaatgg gaaataccgt tatacggtct
    18661 tttataaagg acagtttgct ctagattcag atgaaacatc aacgattgaa ggaagtaaag
    18721 taagttttac tcatccaact tggaagggtt catttgtaga tgtaccagga cttggatata
    18781 tgtattcagt tgatgaagat gatgaaggcg tggataaagc aatgatcgga aattggttta
    18841 caaaagtagc aattccaatt gaagaagcag aactttcagg aggtacagaa taatgtcaaa
    18901 atatcaaaca acgattaaat taacgaaaaa agatgaagaa ggtaaatatg agcaagtaca
    18961 atttaaatct gctgaatttc taccaggccc agtcgtagaa gaagcagcag aagtaatgga
    19021 gggaatgcaa aatgctgtag atggaaaatc agtatcagaa gcattaagtc gagcttattc
    19081 atttattgca gatattttgt ttgaaggaca gtttactggt gaagattatc gtcaagggat
    19141 cgatgctcga gaaattgctt cgttgacagg taagttatta aaatctgtta ctgcaggctt
    19201 tgatgaaact tatacagaaa cgaaaaaaaa gtaagcgaag ctctcaaata tccttttttt
    19261 aaacattcga ttacttatcg agaattagat ttaaagacgc aattactcga agcaggttgg
    19321 acgttaccag aaattgaacg tactgacttt gacgagttaa tgcgtctttt tgcttttcga
    19381 gatgcagtaa aagagcatga ggatgttgag tactacgata acttcaccca attttaggag
    19441 gtgatacttt gaataacgat gacctaattc tgaagatgat actagatgaa tctggtttta
    19501 ctgccggtat gaataatgct gtcaaaaagt tgaactcttt tgatgaaaca atcgaaagaa
    19561 aaagtagaaa tagtggcagt tcattaggta gtatttggaa aatatttgct ggaagttttc
    19621 tagctagcgg agtaactaga atcgtaggag ctggctttga tctaatcaag ggttccataa
    19681 gtggagcggt tgatcgagta gatacgatga ataacgctct acgaaatttc caaaatatgg
    19741 gatttagtaa ttcagaaatt atgaagaata tcggaaagaa tgggctttta tctcaaggta
    19801 ttcaaggact tcctactgct ttgaatgatg cgataagtca tgttcaactt cttgcttctt
    19861 ctacaggtga tttaactcgt tcaactcaaa tatttaaagc tttaaatgat ggaattcttg
    19921 gtttcggtgg ttcaactgat caagttaatg aagctgttat tcaattatct caaagtttct
    19981 caaacggaaa agtagacgca caaacttgga actcaatgat caacgctcaa cttggaccta
    20041 ctctttctgc tattgctaaa aagatgggaa ttacaatggg agatctgaaa gaaggtttat
    20101 ctcaaggtaa gatttctgtt gaagaattcc aaaatcaatt aatagaaatg gataccaaag
    20161 gtggcggagg acttaaatca ttaagtcaaa tcgctaaaga ttctactaag ggaattaaaa
    20221 cctctataca aaatgcaaaa acagctgtta cacgtggtgt tggtgaggta atagaaggat
    20281 taaataaagc attagtagat tcagatttag gtggatttaa gggaattatt gataaagtgg
    20341 gcagttcaat ggaatcgttc ttaaaagtaa ttgctgcaaa tattcctaca gcagtatcat
    20401 ttttaagtaa tttatttaac gaaattcaaa aatttggttc tgctttgaaa ttcatgatgc
    20461 cctttcttgt tcctgcagct accgcttttg gagcgttcat gtttcaactt aaaggtatac
    20521 cagcaataat aaaaagcttc aataatttta agaatgccat aattggcgtt ggaaattcat
    20581 taaagattat gggggcaata gctgctgcta attcatttgt tttaattatt ggtgcagtcg
    20641 ttggtgcaat agctgttttc ggttacttta tggcaaccaa tgaagagctt agaaacaagg
    20701 ttatatctat ttggaatgat gtgaaagatt ccgtaattgg tgtattaaaa aatataaagg
    20761 actggggaat tgatacttgg aattctgcta aagaaatggc atcaaatgca gttgagggtg
    20821 tcaaagatgc ttggtcagga acaaaggaat ggttttctaa cacctggaaa ggtattaagg
    20881 atggggccac aggtttattt gataaaacag tagagacttc aagaaatgca gtcgatagtg
    20941 taaaaaatgc atggtctaat atgaagaaat ggttttctga tacttggcaa agtataaaag
    21001 attcagccag agaaaaatgg aatggaatca aaggttctat tatgtcagtt gctggtccat
    21061 tgattacagg tataaagaat gcatttttac atgttacttt ttatctagag accttatgga
    21121 ataatttagt tgagattggt aaaaacgtct ttgagatttt aaaaaatgtt atacttgcgc
    21181 cggttttgtt tattacctcc atgatttctg gtggatggga agaaacaaaa aataatatga
    21241 ttgctgtttg gaataatatt aaaga
//
LOCUS       DADVXV010000050        21200 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.051, whole genome shotgun sequence.
ACCESSION   DADVXV010000050 DADVXV010000000
VERSION     DADVXV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.051"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            474..725
                     /locus_tag="KB969_001739"
     CDS             474..725
                     /locus_tag="KB969_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869724.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
     gene            759..1037
                     /locus_tag="KB969_001740"
     CDS             759..1037
                     /locus_tag="KB969_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869725.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            1634..1891
                     /locus_tag="KB969_001741"
     CDS             1634..1891
                     /locus_tag="KB969_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869726.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            2004..2615
                     /locus_tag="KB969_001742"
     CDS             2004..2615
                     /locus_tag="KB969_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869727.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            2794..3351
                     /locus_tag="KB969_001743"
     CDS             2794..3351
                     /locus_tag="KB969_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869728.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(4050..4571)
                     /locus_tag="KB969_001744"
     CDS             complement(4050..4571)
                     /locus_tag="KB969_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBB6869729.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            4770..8462
                     /gene="nifJ"
                     /locus_tag="KB969_001745"
     CDS             4770..8462
                     /gene="nifJ"
                     /locus_tag="KB969_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBB6869730.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            8651..9538
                     /locus_tag="KB969_001746"
     CDS             8651..9538
                     /locus_tag="KB969_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBB6869731.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            9535..10704
                     /locus_tag="KB969_001747"
     CDS             9535..10704
                     /locus_tag="KB969_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869732.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            10728..12083
                     /locus_tag="KB969_001748"
     CDS             10728..12083
                     /locus_tag="KB969_001748"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBB6869733.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(12155..13960)
                     /gene="glmS"
                     /locus_tag="KB969_001749"
     CDS             complement(12155..13960)
                     /gene="glmS"
                     /locus_tag="KB969_001749"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBB6869734.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            14369..14659
                     /locus_tag="KB969_001750"
     CDS             14369..14659
                     /locus_tag="KB969_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869735.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            14672..15697
                     /gene="sppA"
                     /locus_tag="KB969_001751"
     CDS             14672..15697
                     /gene="sppA"
                     /locus_tag="KB969_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBB6869736.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            15700..16359
                     /locus_tag="KB969_001752"
     CDS             15700..16359
                     /locus_tag="KB969_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBB6869737.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            16516..17448
                     /locus_tag="KB969_001753"
     CDS             16516..17448
                     /locus_tag="KB969_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869738.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            17602..18891
                     /locus_tag="KB969_001754"
     CDS             17602..18891
                     /locus_tag="KB969_001754"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBB6869739.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            19138..20388
                     /gene="clpX"
                     /locus_tag="KB969_001755"
     CDS             19138..20388
                     /gene="clpX"
                     /locus_tag="KB969_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBB6869740.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALSAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            20471..21058
                     /locus_tag="KB969_001756"
     CDS             20471..21058
                     /locus_tag="KB969_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBB6869741.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
BASE COUNT         7035 a         3619 c         4581 g         5965 t
ORIGIN      
        1 acaaataatt ggtttattct ggcaggcgta atgctttttt ctagtttcta tttatttagt
       61 aatgctctat tagcacagcg agggaaatat aagtttaaaa tattagatta gatattattt
      121 ttagagggga taaatataaa atgaaaagag gttatttata atggaaaaag tattaccaat
      181 taagagctac tgtattccaa ggcttttcat catagaattt caaaagtaaa gacatgtgtt
      241 tcacaaatag tgtctatcct ggctaaataa ttcttccact atctgcttta atttcagtag
      301 acttttcggc aagttatttg ctaatgagat gaatagagat tacaactcgc ctataaccgc
      361 ttaaaacaag cttttttaaa gtatagttag caagtcgtat tcatatgttc aaagaggagg
      421 gcttatgaac tttgaattca ttccgtgtga acagaacagt agggggaagt aaaatgaaag
      481 aaaagcctat aaataaatgg tcattgtata aaaattcaat gtttggagtt gttatctttg
      541 gtgtttgtgc tggattattc cttttcatat tattacaaac ggtgactctt ttctcttcta
      601 atcctactta tggatggaga gacagtatag ccttagggat gtttgcggga ggatatggat
      661 tcttattgtt gttctcaatt ctcacactaa gtccaatcca tggactcatt caactttgga
      721 agtaagaacg agccttaaac ttttcgttct cggaagaaat ggaaaaacac aacataacag
      781 gcagtatgta tgtggatgat caatggttta tcagcactga tgaggtaaaa atagctgcca
      841 ttaggagaga ttacctgcag aaaattcata aaataaaaga tcctaatggg aaaaaggcaa
      901 ggttaattat aactttgata acatctaatg gtaagaagtt aaaacttgca ggatcatatg
      961 ataatgttaa aaagttcgaa cattggtatc tgcaaaaaga cagcattagt cttaataaac
     1021 aatttgaaaa aaattaatca aagtcatcgg caacacgaat aatttgacat cttgatattg
     1081 tgatataagc aaaaacggca tttctgagac cgaacagcat aaaaaattta aatgttggaa
     1141 tttatataag caaaacccaa gaagctagat gcgatagagc atttaatttc ttggggtttt
     1201 gcttgggaat cagcatatca attaaaatga tcatctcggt atttcaaaag tgggtacgat
     1261 tacaaatagt tggagcaaaa tagtgggtaa aattaccatt ccagtgtctg tcttgcctct
     1321 ttttcgtcaa tcacaaatag acgagattca taggaaaaat cgatacaggg tatgatttca
     1381 atgatattat gaccaattac aaaatagatt gataaagcat tttttgcatt tttataatag
     1441 tttattgata ataatgtatg agatacagta taatgattta aaaggtaacg tgttgtgacc
     1501 gaattaaatg aattaatgcc tattttttat attccttagt ggacaaaaat ggagacagtg
     1561 aagttaggag cattgtatcc tttgttgcgt agttcaaaaa agtaagcgat ttctataatg
     1621 gtcagggtaa acggtgaggg ctgtccacgt aaatcctact attgaaatca caatgatcgg
     1681 acattcaaaa ggtggtgctg aagcagcaaa ttcagtagct ataaatacga atgcgattat
     1741 atttaatcca gcgacagtaa atttatctgc ttatgaatta gactcaaaca catatacagc
     1801 aaacatggta gcttatgttg tcgagggaga tgcattaaat gttgtttttg gaggagtata
     1861 cacctattgg agaattaatc atgttagata gacaatatga tgcaccttag tggagaatga
     1921 tatctcgcat aggtaactca gtaaaaaatc aaggtatgga agcaattatc tctgcattgg
     1981 aagatcgata tagataggcg gatatgaata gtaatagggg gaataaaatg gaatacaatg
     2041 gatcaatgag aattgtacaa attatatttt ggattacatc gggaattgtg atcataggag
     2101 gagttttttt gatgttgcca agcttaatat ttcctttctt tgcattaatc tcacctaaaa
     2161 tacccgaacc ggaaatcacc tatggagaat ttccatttag gattgaatac gaactagatg
     2221 gacagattaa cataattgaa gatactgtca tagctgagtt taacgggtgt gagttcagcg
     2281 caggttctat gaaaagagaa cgaagatgga gaagtagatt agctagtggt agagaagatc
     2341 taccttttgg ggacgatcta ggaatctatt ttagtcgagg aagtgcgcaa tattatatgg
     2401 gggaaaatgt acaatcaatg tcattaaaac cacatatagc ccttagaaat ctcgaggaag
     2461 gttttaaaag agaggtagac tttatattag gagaaagtgg atacataaga actgtactta
     2521 atttcggaga agcgcaagaa gttttgacac aatacggaat taccttaatc aactgggaaa
     2581 tatctgaacc gattgttaac aattttggtg attagaaaac aattacgata aatagaaaca
     2641 agccaaatca tcagcaagta aaagctgatg atttggcctt tcttatacga gtagtaggaa
     2701 ttcatagcga atattattac gaccagtaga tattttgata ttaaaggagt attacgaact
     2761 aatatgtgag aatgtagagg tgatgtgcga ataatgagaa atttatcaaa tagaaacaaa
     2821 atattaatca ttattgttgt tatagctgtg tttcatctgg gaacgaatgc ggttttaagt
     2881 agaataatat tgggtcctaa gccaccaaga ccagaaatta cccgagggga gtttgatttt
     2941 agattagaat atgaagtaga tggggaaagg attgtgatag aagatacaat tgttgcatta
     3001 tttgatggat tttctgcaga tgcaggtagc atggcatggt atcgcacgtg gcgtctacat
     3061 ttagcaagtg atagacgatc acgaaatatc ttattagatg aattagagga tggtcgaaga
     3121 atatattatg tcccagaaag tgctaactat tctatgggag atgtacagaa aaaaagagag
     3181 cctaatccta attggtatcc atttaatggc gtaacaatag aatatccacg caataaaaca
     3241 cctgaaatag gtgcaaaatt tataagtggt ttagaagatc tgtacgatag gtttggaatc
     3301 cgtcttatta gttgggaaca cgatccacca atagaaaatc gctttgaata atcgaaatct
     3361 actaatccat ttcatcagcc agtgaatgtt gtaatggaac aatttggttt agtgttcaaa
     3421 accattgaaa tactaggctg tgatcagcaa aaatgaatct gaataaaaaa gagagcaact
     3481 attagctgag aggagttaat agttgttagc tttatacgaa tcaaagtggc aaatacagat
     3541 gcgtatgcat ttgtgtttgc catcttgcgt ttggtagacg agataggtat aagctaaaga
     3601 aacaacttgt ttaaaataaa cgacctagct caacaaatga ccatctaatc aactaacagc
     3661 atacataaaa gcaactattt ttgaagtaga attgaaatcg ggataactta aaaagtgatt
     3721 gggatactag tgagaatcac cgtacataaa tattactcgt taagggaaat tgagaaattt
     3781 tgtatgaaaa tttaagaatt agttagtatg cgcaagtcaa aaatatgaat aaattatttg
     3841 gtggagataa tttgcttagc ttgtcataag aaatgagata atctggcaga tgcaagcttt
     3901 tggacaccat ttattcggaa taaggaggct gggacagaag cgtttaactc caagaaataa
     3961 gaaggagttg cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc
     4021 tttacttttg tcccacgctc cttatttttt tattttgttt ggatcaattc ttttaattcc
     4081 tctattgaaa tagattcatc aaagatttct ttacccaaga tgacagttgg aacaaatcga
     4141 atatgtgctt gctcagcttc gttgatgaca gcttggctca gctgttcgtc tttttgttct
     4201 gtcagcttta gtttatctac tgcaaaatcc gctacttctt ggagagaaag atgtttccac
     4261 tcgtcttgag tatcgaatat ttgtttgatc tctttgatcg ctttttggcc atcgctgatt
     4321 gtgagatacc ggtgcatcac gttccctcgc tgtaagcttt ctttttcttt atcgaacaat
     4381 ttgatcactc gctgcaattg cccgctttgg actgcttctt ctaatagctc ataagattct
     4441 tcaaaccatt gtcggcaata cggacaagct aagttgatga attcgaccat ttttttagga
     4501 gcattcgatg aaccataaag gattcctttt tgtgtatttg ttttcgttgc atcaatcact
     4561 gatatatcca tgttaaaaca cctctttcgc ttatagttta tacatgtctg acaaaaaaag
     4621 gcaacgattt agactgtttg tctaaaaatt agatgaccaa ttcaaataga tacatgtaaa
     4681 atatttttat aaataaaaga aaaaaatggc atgttttacg ttataatgga acagataata
     4741 agagagaata tgaacaagga tgatgaatca tgcgaaaaat gaaaacaatg gatggcaata
     4801 cggcagccgc atatatttct tatgcattta ccgagattgc tgcaatatat ccaataacac
     4861 ccagttcgac catggctgaa ttagtagatc aatggtcagc agcaggaaaa gaaaacgtat
     4921 tcggtcaacc agtaaaagta gtagaaatgc aatccgaagc aggagcagct ggtgtggtcc
     4981 atggatcatt gaaaactggt gcactgacaa ctacatatac cgcttcacaa gggctgcttt
     5041 tgatgatacc gaatatgtac aagattgctg gggaactact gccaagtgtt ttccacgttg
     5101 ctagtcgggc agtgacgaca aatgcgttga atattttcgg agatcacgga gacgtgatgg
     5161 ctgcaagaca aacaggattt gctatgttag ctgaaagcag tgtacaagaa gtgatggatt
     5221 tagcacctgt tgcccatctt gcttctattg aaggagaagt cccttttttg aatttctttg
     5281 atggattccg tacgagtcac gagattcaaa aaatcgaagt tttggaatat gaagaattag
     5341 ctcctctgat caatcaggag aaattagctt catttcgtaa acgagggatg aatcccaatc
     5401 atccgactgt tagtggtacg aaccagaatc cagacatcca ttttcaacaa cgggaaacga
     5461 tcaaccccta ttatgataaa ttacctgaaa tcgttcaaaa atatatgaaa gagatcaacc
     5521 gattacgagg aacttcttat gacttggtga cttattacgg agcagacgat gcggaagaag
     5581 tcattgtttc tatgggatca gttgcacaga cgattgaaca aacgattgat tacttgaatg
     5641 caaacggacg gaaaacaggt tttttgaata tccatcttta tcgtcctttt ccagtggaaa
     5701 cattcgtgca aaagttgcct catacagtaa aaacaattgc tgttcttgat cgaagtaaag
     5761 aaccaggggc aggtggagaa cctctcttat tagacgttca aagtgcgtta tatgattctg
     5821 aacttcgccc ggctgttatt ggtggtcgct acggattggg gtctaaagat gtgactcccg
     5881 accaaatctc agcagttttt gatgaattga aaaaagaccc aagcatacgc aaaaaacggt
     5941 ttaccatagg gatcgtggat gatgtgactt atcaatcttt ggaaccaaag gaaagtctgg
     6001 atttgacaga accgcaaaca ttccaggcca agttttgggg atttggatct gacggaacag
     6061 ttggagcaaa taaatcagct atcaagatta ttggagatca caccgataaa tatgcgcaag
     6121 gctattttta ttatgattcg aaaaaatctg gcggtctgac tgtctctcat cttcgttttg
     6181 gagatacgcc gatacgttca gcgtatcttg tcgagcatgc ggaccttgtt gcctgtcaca
     6241 caccagctta cctgcatagc tatgacttgg tcaaaggatt gaagccaggt ggcatttttt
     6301 tattgaatac tctttggagc gacgaacaat tagaaacgca tctgccctta aaattaaaac
     6361 gttacttggc tgaaaataac attagattct atacgatcaa tgccatgaga ttggcccaag
     6421 aagtcggttt gggacgccgg atcaatacgg caatggaaac ggcttttttt aaattagctg
     6481 acatcattcc ttttgatgag gtgcttccgc tgctaaaaga agaagccctg aaaagctatg
     6541 gacataaatc aatggctatc gtagaaaaaa acatacaagc aatcgatcgg acgaccgaac
     6601 tgcttcatca agtcgcgatc ccagaccatt ggagaacgtt ggagatgcct gaaaaaatca
     6661 ataaaaggaa cactggttat atacaagaaa tacttgaacc agtgaatgca caggaaggaa
     6721 atcaactctc tgttggtaca cttgtagcaa atggaatgac aactggcgaa atgcctttag
     6781 gaacggcttc tatggaaaag cggggcgtcg ctttagaagt acctgagtgg attagtgatc
     6841 gctgtacgat gtgtaatgaa tgtgcctttg tttgtcctca tgctgccatc cgtccatttt
     6901 tagcagatga agaggaaatg gaagaagcgc cagaaggatt tatcgtgaga gaaatgcgag
     6961 gcgcagacgg cgtaaaatac cgtatccaag tttcagtgga agactgtaca ggttgtggtc
     7021 tgtgtgtaga ggcttgtccc gcaaaagaaa aagctttagt gatgaagcct tatgaagaac
     7081 agaaagaaca agctgtgaat tgggcttttg caatgacatt aagacaaaaa gcaaatccag
     7141 tcaaaggaaa gaatactgtc ttgtctacac aattcaatca accgcttctt gaattctcgg
     7201 gcgcttgctc aggctgtggc gaaacacctt atgtaaaatt attgacacaa atgttcggtg
     7261 atcgaatgat gatcgcgaat gcgacaggct gttcttctat ttggggcggt gcttctcctg
     7321 cttctcctta tacgaccaat gaatgtggtc aagggcctgc atggtcaaat tctttattgg
     7381 aagataatgc tgaatttggt tatggtatgc ttctagcggc acagactcgt cgcgaggctt
     7441 tggcaagttc aatcaaagaa gtattgccaa aagtatcaga agaactacga gaattgatgg
     7501 aagactggtt agtacacatg tttgagagtg aaggaacgca gcaaagagca gcaaaactgc
     7561 aagctgcgat cgaaagcgaa cgatcaattt tccctgaact ggaggatata tacaagagaa
     7621 aggatctatt cgtaaaaaac agccaatgga tgattggtgg agacggatgg gcttacgaca
     7681 ttggttttgg cgggatcgat catgtacttg ccagcggagc agacgtgaat atccttgttt
     7741 tggataacga agtctattcc aatactggcg gtcaaacctc aaaagcaaca ccagcttcgg
     7801 caatcgctaa attttcggct agtggaaagt atgcttcaaa gaaagatcta ggaatgatgg
     7861 cgatgacata tggaaatgtt tatgtggcgc aaattgcttc aggtgccaat caaatgcaaa
     7921 cgatcaaggc atttgaagaa gcagaaaagt atcctggtcc ttctctgatt attgcctata
     7981 cgccttgtat cacacatggc ttgcttggcg gaatgaaaga atcgcttaaa gaagcaaaag
     8041 aagctgtttc ttctggttat tggtcattat atcgatataa ccctacaatg gtcgaaaaaa
     8101 acaagaaccc aatgactttg gactacaaaa aacctgattt ctctgctatg cctgatttca
     8161 tgaggaaaca agttcgcttt tcctcgctag ataacgcaaa tccaaatctt gcaaaagctt
     8221 tatttgaaaa gactgtccac gacgctaaaa cacgttttta caactatgct gcactgacgg
     8281 gagaattaga aaaaatcaag aaacgacttg aaccagagga atctatcgat gtacccgtta
     8341 agactagaaa agaaaaaacg acggaccttg aagcagaaga aagaagagct gctagaagag
     8401 ctgccagagc agaacgacgt aaaaaaatgg aacaagctac aaaagaaaaa aaggaaaaat
     8461 aacagaaaaa atataatgaa taattctctg aagtttaaaa atatttattg cagagaaaaa
     8521 taaaacgcat acttgcaatt ttcttgaaaa ttatgcgttt ttctcaagaa aaatacgagc
     8581 atatcagcct ctaaaattaa aacatatgat atactagaga ggaaatctca aaagagaaga
     8641 gaggcttttt atgtcatttc aaatcgggga actttttaat ttggactatt ggcagcaaat
     8701 gttttccggt gacttgttct ctctgaattt tttggtgaac atacttgata ttctggttgt
     8761 ctggtatctt gtatacaaac tgatccaact gctgcgaggc acaaaagcga ttcagcttct
     8821 gaaaggtgta gctattttta ttgttatccg aatcgtagcg gaaatcattg gtctgcacac
     8881 cttgtcttgg ctgatgaacc aagtcattac gtacggggtg atagctgcta tcgtgatttt
     8941 tcagccggaa atccggagag gactggaaca tcttggacgc agttcgcttt tcaaacaatc
     9001 aaaaagcgaa cagcaggaag atgagaagat gatcttgtct tttgacaaag ccatccaata
     9061 tatgtccaag cgaaaaatcg gtgcgttgat cactatcgaa cgtcatactg gattagatga
     9121 gtatattgag acagggattg ctttagatgc agatatcact ggggagctgc tgatcaatat
     9181 ctttattcct aatacaccgc tgcatgacgg tgcagttatt gtaaaagaag gaaagatcgc
     9241 agtagcaagc gcctatcttc ctctatcaga aagtatgttg atccctaaag aattcgggac
     9301 tcgacaccgg gcagctgtcg gtataagcga agtcagtgac gcgattacca tcgttgtctc
     9361 tgaagaaacc ggggacgtca gcatcacgtt agataatgaa ctgatggctg gcttatccca
     9421 gcaagaatat ttggcaatct tgcgtagaga actaattgct gaagagaaaa caaaaaacaa
     9481 gaaaaacgtg attcaatctt tcctagacgg tatgactaag ggaggggatc gcaaatgatc
     9541 tcaaaagaga aacggacaag cattctttac agttttattg cattgctgtt cagtattgcg
     9601 ctgtacttca atgcaaatgg ccagtccgtt ccaaatacgc tttctggaaa tgaagcgtat
     9661 aatcaaacag ttacgggggt gccgatcaag atttcttatg attcaaagcg ctactatatc
     9721 catggatatg aaaatgcagt gactgtcaaa ctttccagtg caaaccgagt tcagttgaat
     9781 gcagaggcaa acgaagatac acggatgttc cgcgtcacag cagatatcac taagctgggc
     9841 gaaggaacac atgaagttcc gctaaaaatt caaaatttga gcagtgctgt cacagcaaag
     9901 atcgaaccat cgactattac agtaacggtt gagaaaaagg taataaaaga tttcgatgtg
     9961 gaaacgttga ttccttcaac gttcacacca tctggatatg aacttgatga tacttccgtt
    10021 agtcctaaaa aagtctctat cactacaggt gacaaaacat tggcagaaat caaacgagta
    10081 gtagctgatg tggacgcttc gatggtcaca gatgatggga ttaatagtga ggtcccaata
    10141 caggcgctga atgcagcagg ggaagtatta agtatcgtct ctgatccagt gcaagtaaca
    10201 gtgagagctg attcgatcaa gccaagcaag tcggtacgac tttatgggat acagcaagga
    10261 acaccagctg ccggggtaga aagctatgat ttcagttttt caaaactgga agcagaagta
    10321 agcggctcta gcgatttgct tgcatcgatc ggtgacagta ttgctgtacc gatcaatgtc
    10381 tcaggtatca atcatcgaac aactcgtaaa attgaaatac cagtagaaga ggggttaagt
    10441 atcaagcccg aatcagttag tgtggagatt acacccgtgt tgcaaacgtc aagcagtagc
    10501 tctgcttcga cgagcagtcg gacacaagaa aatacaagta cgagtagaag tatttcatct
    10561 gctgattcag gaacggaacc atcgacaaca accatttctt ccagttcgga atctgggaca
    10621 agcagctcga ccacaagtac agaagaaaca tcagaaacaa gcgaatcaac acaaatgagc
    10681 agaacaaatt cctcagaaaa ttaagttaaa ggagtaattt tacaactatg ggtaaatatt
    10741 ttggaacaga cggcgtacgc ggtgaagcca acaaggaact tacgccagaa cttgcattta
    10801 agctgggacg gtgcggaggt tatgtcctaa gccagcatga agaagaagga aaacgcccac
    10861 gcgtgttagt agggcgggat acaagaatct caggtcaaat gttagaagaa gcgctgattt
    10921 caggactttt atcggtgggt atcgaagtgt tccagctagg tgtgatctct acaccaggtg
    10981 ttgcttatct gacacgtttg caaaaagcaa gcgcaggggt catgatttct gcttctcata
    11041 atccagcaca agataatgga atcaaatttt tcggtgcaga tggttttaaa ctagtagatg
    11101 accaagagct agaaattgaa gcattattag atgctgaagt ggatgaattg cctcgtccat
    11161 cagctgaagg attgggaact gtagaagaat ttccagaagg cttattgaaa tattctcaat
    11221 tccttgtaca aacgatcaac ggtgaccttt ccggtttgac catttgtgtc gatgcagcaa
    11281 acggagcaac ttcaacaagt gttaatcgtt tgtttgccga tcttgaaaca gatttttata
    11341 caatgggcac aaatccagac gggttaaata tcaatgacgg cgtaggctct acccatccag
    11401 aacgtttagc tgagatggtc gttgaaaaag gagcagatgc tggactagct ttcgatggcg
    11461 atggcgatcg tattattgcg gtggatgaac ttggaaacat tgtcgacggt gataaaatca
    11521 tgtttatctg tgctaaatac ttggcagaaa aaaatcgatt gaaaaaagat acgatcgtta
    11581 cgactgtcat gagtaactta ggattccaca aagcggtgga aggaatcggt ttgaaagatg
    11641 tcgttacaca agttggtgat cgttacgttg tagaagaaat gcgcaaaaac gattataact
    11701 ttggcggcga gcagtctggg cacatgattt tcttagattt taacacaact ggagatggga
    11761 tgctttcagg aattcagtta ctgaatatca tgaaacagac aggtaagaaa ttatcagagc
    11821 ttgcagcaga ggtaacaatc tatccgcaaa aattagtgaa tatccgcgta agtgataaaa
    11881 acggtgcgat ggatgttccg gcaatcaaaa aagtgattga agaggcagaa gctgaaatgg
    11941 gatcagaagg aagaatccta gttcgtcctt ccggtacaga accattactt cgagtgatgg
    12001 cagaagcgcc tactgatgag aaagttaatt actatgtcga taaaatcgcg gcagtagtca
    12061 aagaagaaat cggactggat taagagatat tttcataaaa aataaaagaa caaggaccag
    12121 tgtcagatgt ctgacactgg tccttgttct tttattattc tactgtcact gatttcgcta
    12181 aattacgtgg tttgtcaacg tcgaatcccc gtaatagcgt tgcgtaatat gcaagtaatt
    12241 gagtcggtac gactgtggtt agagtagtta gataagggtg gacagttggt agcaccagct
    12301 ggtcactttc cttttctaat ccctctgaga caataactag tgttttagcg ccacggcttt
    12361 cgacttcttt caggtttcct cgagtatgcg caccagtcac ttcttcactg atgattccga
    12421 tcactggtgt tccttcttcg atcaaagcaa tcgttccatg tttcaattcg ccagcggcaa
    12481 aaccttctgc ctggatataa ctgatttctt tcaatttcaa agcagcttca agagaaacgt
    12541 tgtagtcagc accacgtcca atgtaaaagg catttcttgt atcgctgaga tatacttctg
    12601 ccaactcttc taaataatct ttttgggcga tgaccgattc catcgcatta gcaactaaac
    12661 tcaattcatg agtgatatcg aatacaagag aagtttcaaa ttctttttta tcaccgatag
    12721 ctttggctaa taaagttagt acagctattt gtgcagtata agctttcgtt gatgctactg
    12781 cgatttcggg tccagcatgc aatagcagtg taaaggatgc ttcccgcgaa agagtagaac
    12841 cagcaacatt tgtaatcgta agtgaagggt agccgagacg gttgattttt accagcactt
    12901 ggcggctgtc tgctgtttcg ccactttgac tcaagaaaat aaagaatggt ttttttgaaa
    12961 gaagaggtgt gttatagcca aattcactgg ctaaatgaac ctcaacagga atctgtgtca
    13021 atttttccaa agtctgttta cctgctaacc ccgcatggta actagttccg caagcaacga
    13081 tatagattcg atcgctatca gacaatgtat cgaccagctt ttgatcaaga gagacacgat
    13141 tgtcttctgt tacgtatttt tgagcgatac gacgcatgat aataggctgt tcgtcgattt
    13201 ctttcagcat ataaaaagga taggtacctt tctcgatatc tgaagcatct acttgtgctt
    13261 cgaatgaaga acgttctacg atgtcacctg caaaattttg aataataact ttttctgatg
    13321 tgacggtaac catctcttca tcttcaatct caacgaattc cttcgtatga gcaagcatag
    13381 ccattgcatc gctggcaatc acattgaatc catcgccgag tccgattaat agtggacttt
    13441 tatttttagc gacgtaaata acatcaggtg ctgtccgatc aatcaaagcg aaagcgtaag
    13501 aacctttgat gacccgcaaa gcttttaaaa acgcctcttg cgttgtagta tccttcgcga
    13561 aagtttcaat tagatgagcg ataatctcag tatcggtctc accaataaag tggtcatttg
    13621 ctaaataagc aattttaagt tcttcaaagt tttcgattac gccgttgtga acgagcacga
    13681 agcgtccact ttgggaagta tgtggatggg cgttttcttc agaaggttgc ccgtgagttg
    13741 cccatcgtgt atgaccaata cctatatttc ctgtagtatc aatatttatt ttgtttttca
    13801 aattttgaat tctgccttgt gctttgacca gataatcagt tgtgccatct gagacaaaga
    13861 taccagctga atcataacca cggtattcta atttttctag accgtcaatc aatcctggtg
    13921 ttacattttt taatccaatc attccaacaa ttccgcacat aaaaaacatc ctactttcta
    13981 taatgaattc gtatgaatgc ttccagctgc aggaaaatcc ttttgtttta tctttgcaga
    14041 cattttttgt ggattttctg tagagtgcag tccctagggc catccgccga atctttcgat
    14101 aaaccctctc ctcgtcatct gtttacacag acctggcgct atcctaaaag gtataactat
    14161 cctccttttt gttttttatc tggaaacatt taaaatcata accttttgcg aatgttcttg
    14221 tcaacaaaaa aagaataaaa aataaattgg tatatatcaa attctttgtc aaatgtcctt
    14281 tttatgtcaa aaaataatgg gtttttatct atcatctttt tcaggagttc ggtacaatag
    14341 aaagtaatcg gatagaggag gagtaaaaat ggattcaaaa attgagatca tgacactggg
    14401 aatgttaaaa aaacaattgt ccaaattcga agcatcagct ggtgtatcag atgatacgaa
    14461 aatattttta gatactggct gggatagcat ccaagaaatc gcacctgatg ccttggaagt
    14521 tgctcaagct cgtgagttta cggtagaaga tgaattaaca aaagagtcgt tttccgggta
    14581 tgcgcgggaa gaaaaagcag agcggttcga cacttctgag cagtcagaaa ctgtgatcgt
    14641 cataaaaaac ttgtattaga aaggagaaag aatgaataaa agacgttggg cagcagttct
    14701 gattgctgca ggattatttg tggtttcgtt agtttcagct agtttgacta agcctcagga
    14761 aaacgatcaa attgagggat tgaacagttg gttatatggg gatgaagaac tagctccaaa
    14821 tgtgttggaa gagggagaca gtacgcaaaa aatcgtaaaa ttatcagtag atggaacgat
    14881 tgctgcggga gggtcttcag gtttatttgc ttctgaaggt tacaatcata aaaattttat
    14941 ggaacaactg aaggcgattg aagaagatcc aacagtcaaa ggtatctttt tagaagtaaa
    15001 ttctcctggt ggcggtgtct acgaaagtgc ggaaatcgct aagaaattgg atacgattcg
    15061 taaagaacat gatatcccaa tgtatgtcag catgaaaaac atggcagcta gcggtggcta
    15121 ctatatttct gctcaagcag ataaaatctt tgcaacagaa gaaacagtga ccggctcaat
    15181 tggtgtgatc atgtcaggat tgaattattc aggacttcta gaaaaactgg gtgtggaaga
    15241 tacaacagtt aaaagcggag cgttgaaaga tatgggttca ggaacgcgac cagagacaaa
    15301 agaagaagaa gcggtgcttc aagcatatat cgacagcgca tatagtcgtt ttgtagcaat
    15361 cgtcagcgag ggacggaata aatctgaaga agaagtcaaa aaaattgctg atggaaggat
    15421 ttatgatggt gtccaagcaa aagaagtagg tttagtcgat gaattgggat ttcctgaaga
    15481 tgctttaaaa gctatacgaa aggaacaaca gcttgaagat gcggaactag tagaatattc
    15541 ttccacgcca tctgggtttg ctagtacatg gttaggaagt aaactagcag aattccaggg
    15601 attgaagcct tctgagacta gtcagatctt atccgttctt gagaatctag ggacagcgga
    15661 atcaccaaaa gcaatgtatt attacggagg tgagtaagca tgtcagagct ttcaaatgaa
    15721 aataaggaac aagaaaaaga taagcaacag cagcctgctg taggacctga ctccaacttt
    15781 tcccaaaagg tactgagctc ttttgaaaga gagcctttga cgcccgaaga aatcaaaaag
    15841 aaacaacgta aatggaaaaa gtatacggac acaagaaatg aaccgccaaa agcaaatgat
    15901 tttcctaagt atttctatgc aggttttttt atccgaatgt ttgccttctt ggtcgatctt
    15961 ttgtgtatcg gagctattac gcgtttaaca cttggtattg ccaaaaatct aggttggctt
    16021 aatttttcag attcttatct gagtctctac ggattcacag ccttacttat ttatctagcg
    16081 tattttattt tattgacgaa attcaatcat ggccaaacga ttgggaaaat gatctttggt
    16141 attcgagtca tcagctttga tgaagaagaa cttagctggt caaccgtttt agttagagaa
    16201 ggtgcttgcc ggttcattct aaaatttcct ttgctgatgt tagggtatct tccagcagtc
    16261 tttaatcaga aaaagcaaca tctgggcgat tttttcacta atacaagtgt tgttacgatc
    16321 aatctgatca aagcgttcaa ccaggaagtc aacagctgat gagcaataaa aagcagtaac
    16381 agttgaaagc accttctaaa agtcagatct aaaatctagc ttttagaggg tgcttcagtt
    16441 atttttaatt gtcatgcttt ttttgttttg ctactattga acatgagctg aatatgagca
    16501 agaggaggac actgcgtgaa gccgattgat tttccagaaa aatatgagaa tttaatgcga
    16561 gtggcacaac aagcactagc aaaccagcaa tatcagcagg caaaagaatt atttcaacga
    16621 gcttacgagt tgaaagaaag ctttgaggct aatagcctgc ttgttttttg tctttacgag
    16681 ttggacgaga aaaaagaagc attgaagcaa gcactcttgc atgaaaaaca gtatcttcaa
    16741 aatgaggagt ttgctgaatt ttattttgac ttgttaatca gtacacaaga ttttttatat
    16801 gctagaaaat tgatagcaag tacagatttt tatgaagctt tcgagcagcg ggtcattgaa
    16861 aaaatccaat ttgcagaaga attatccgga caaatggaga ggcagaagat caaggcactc
    16921 cacaataaat cggaggaact tccttcgttg gaacctgcac gtcagcttgc gtctattgat
    16981 gagatcgaac agcttcctta tcatgagttt atccaaacag cgagtaaact tattgtatcg
    17041 ccagaggtcc atattttagc aagggcaaaa ttactggaga cacttaggca attgaacgaa
    17101 tgccatcctg ttttctattt gacgattgaa gaaaagttag tcaaagtcat accaaaagat
    17161 ctgccaaagc cgcagcagca ggcaagttac cagcaattat gtgtattttc agatcgttac
    17221 gggaatgaag atgcgctgct tagttccgtg ttaaaagaag aattcacgtt gcaatctgca
    17281 attgtttatc ctgtctatga tacatacatc gaagacccga agcgctggtt tcaactgact
    17341 gtagaggcgt gtacaggaaa aacgatgtat gaaggtacag aagatgaaaa acaagatttt
    17401 ttaaaaaaaa gagaaaaaat tttgcagcaa atgatcttct tccattagat tttatcagtg
    17461 aaaaagataa aaatgttatg aaaaacaagg attctatcca ttcaatatgt ttacaatttg
    17521 aaagggttag tgtactattt aaaggtatgc atgaaacgtt tttgatgtat aaaatgaatt
    17581 tctaaactcg gagggaatta aatgactgca acatttgaaa aaaaaggcac gaatgatggt
    17641 gttttaaaat ttacgattgc gcaagacgaa atccaaaaag gattaacaac tgcgtttaat
    17701 aaagtgaaaa aaagcttgaa cgtacctgga ttccgtaaag ggaaagtttc tcgtcaagta
    17761 ttcaaccgta tgtacggtga agaagcttta tatgaagatg cattgaatgc tgtattacca
    17821 gaagcttatg aagctgctgt caaagaagct ggcatcgatc ctgtttctca accaaaaatc
    17881 gatgttgaaa gcatggaaaa aggtcaagac tgggtaatca ctgctgaagt aacagtgaaa
    17941 ccagaagtaa aattaggaca atataaagat ctagttgttg aaaaacaaga ccgtgaagta
    18001 acagatgctg acgtggatgc acgtatcaaa cgtgaacaag aagcacaagc tgaattagtt
    18061 atcaaagaag atgctgcagc tgaaaatggc gatacagtag taatcgactt cgaaggcttt
    18121 gtagatggcg aagcgtttga tggcggaaaa ggcgaaaatt actcacttga attaggttca
    18181 ggctcattca ttccaggttt tgaagatcaa ttagttggtc ataaatcagg tgaaagtcta
    18241 gatgtaaatg taactttccc agaagattat caagcagaag atcttgctgg aaaagaagca
    18301 gtcttcaaag tgacaatcca tgaagtaaaa gcaaaagaag tgcctgaatt agatgacgaa
    18361 ttcgcaaaag atgttgatga cgaagtatca acattagacg aattgaaaga aaaatatcgc
    18421 aaagaattag tagaaacaaa agaaaaagca gcggacgatg caaaagatga agcagcgatc
    18481 cgtatggctg ttgaaaacgc agaaatcgtt gaattgccac acgtgatggt tcatgatgaa
    18541 gtacatcgtt caatggacga attcttgaac aacatgcaac gtcaaggtat ctctcctgaa
    18601 atgtactatc aattaactgg ttctacagaa gaagacttgc ataaacaatt cgaaggtgaa
    18661 gcagaaatgc gcacaagaac aaatcttgtg atcgaagcaa ttgcagctgc tgaaaatctt
    18721 caagcaacag aagaagaaat caatgcagaa atccaagaat tatcagaaac atacaacatg
    18781 ccaatcgaac aaatcaaacg cgtgttgaca gaagatatgc tggaacatga tgtgacaatg
    18841 aaaaaagcaa tcgaattgat cacaggtaca gcgacagaag cgaaagaata gaaatcaagt
    18901 aataaatcat ttctgaagaa gctacttcta gaaaattgtt tattcgaaat aagggactgt
    18961 gacacgattt tgtcacagtt ccttattttt tgttaagagt aaaaaatgca aaggtatagg
    19021 tcagttgatc ctttgttaaa cactttttct ttttactaaa ctatgttatg atagtaaaag
    19081 actgtaaagt ctttgatagt ttcttgcata ctttttgcaa gttaaggggt gaagaccatg
    19141 tatgacaatc caagtagcaa tgagaccgta cgctgttctt tttgcgggaa aacccaagaa
    19201 gaagtgaaaa agatcgtagc tggtccaggg gtctacatct gtaatgaatg tatcgaccta
    19261 tgtaaagaaa tcattgatga agaattttat gaagaagctg tacgcgaatt cactgaagtc
    19321 cctaaaccac tagaaattct tgaagtattg aataactacg tgattggaca agatcgcgca
    19381 aaacgctcgt tagctgttgc cgtatacaat cactataaac gtgtcaatca gcaagcacaa
    19441 gaaaacacag atgatgttga actgcaaaaa agcaatatct gcttgatcgg acctacaggg
    19501 tctggtaaaa catttttagc acaaacatta gcaaaaacat tgaatgtacc ttttgcaatc
    19561 gcagatgcga caagtttgac agaagctggt tatgtggggg aagatgtaga aaacattttg
    19621 cttaaattgc ttcaatctgc tgattacaat gtggaacttg cagaaaaagg gatcatctat
    19681 attgatgaga tcgataaaat tgcgcgtaaa agcgaaaatg tatctattac tcgtgacgtt
    19741 tccggcgaag gtgtccaaca agccttgctg aaaattctag aaggaactgt tgcaagtgtg
    19801 ccacctcagg gcggacgtaa acatccacat caagaattta ttcagattga tacgacgaac
    19861 atattgttca tcgtaggtgg tgcatttgat ggcatcgaaa cgattgtgaa gaatcgtatg
    19921 ggcgaaaaga cgattggatt tggtacacaa aaccaaaaac tttctgaaga cgaaagtgtc
    19981 atgcagcata tcattcctga agatttacta aaattcggat tgatccctga gtttatcgga
    20041 cgattacctg ttatggcagc tttagagaaa ttgacaacag atgatctggt acggatcttg
    20101 actgagccga aaaatgcgct agtcaaacaa tatcaaaaac ttctttctct agataatacc
    20161 gaacttgaat tcgaacctga agcgttgagt gccattgcga aaaaagcaat cgaacgcaat
    20221 accggtgctc gaggacttcg ttccatcatt gaagaaatca tgatggatgt gatgtttgat
    20281 atcccttcaa atgaaaacat cgaaaaagtg attatcacaa aagaagcagc tgaattgtct
    20341 ggtgagccaa cagtaatcta taaagattca gagaaaaaag cgggttgatg aaaagaggct
    20401 gccgtaaaag tcattttggc ttttgcgaca gccgcttgct ttattcatca ccttgttaag
    20461 gagagagacc atgaaagtcc atcaagctga aattatcata agtgcagtgg caccaaaaca
    20521 atatccagat acacaattgc cagaaatagc tctggcagga cgatcaaatg tagggaaatc
    20581 ttcttttatc aacacattga ttgatcgaaa gaatttagcc cgtacttccg gtaagccagg
    20641 aaagacccag acattgaatt tttatttgat cgagaacgca ttacattttg tcgatgttcc
    20701 gggatatggg tatgcaaaag tatccaaaac tgagcgagca aaatggggaa agatgatcga
    20761 gacatattta acgactagag accagctacg tgcggtcgtt tctttagtag atttgcgtca
    20821 taagccttct caagaagata tccagatgta tcaatttttg aagtattatg atatccctgt
    20881 aattgttgtt gccactaagg cagataagat ccctcgtggt aaatggaaca agcatgagag
    20941 cgaaatcaaa aaagcgttgg attttgatcg caatgacacg tttattctct tttcttccgt
    21001 tacaaaacag ggaaaagaag aagcgtgggc agcaatcgaa caagcaattg aatcataaaa
    21061 agaataaaaa agacttacca gtcaaactct ttcataaaag tttggctggt aagtcttttt
    21121 ttgagcttaa cttacttttg tttcttgtct tttttctttt cattttgtgg ctgtggtttt
    21181 agaaatcgat cgatctcttc
//
LOCUS       DADVXV010000051        21018 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.052, whole genome shotgun sequence.
ACCESSION   DADVXV010000051 DADVXV010000000
VERSION     DADVXV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.052"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..685)
                     /locus_tag="KB969_001757"
     CDS             complement(<1..685)
                     /locus_tag="KB969_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869742.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKK"
     gene            942..4331
                     /locus_tag="KB969_001758"
     CDS             942..4331
                     /locus_tag="KB969_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBB6869743.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            4334..5755
                     /locus_tag="KB969_001759"
     CDS             4334..5755
                     /locus_tag="KB969_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6869744.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            5752..7629
                     /locus_tag="KB969_001760"
     CDS             5752..7629
                     /locus_tag="KB969_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6869745.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            7721..8563
                     /locus_tag="KB969_001761"
     CDS             7721..8563
                     /locus_tag="KB969_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6869746.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(8715..9590)
                     /locus_tag="KB969_001762"
     CDS             complement(8715..9590)
                     /locus_tag="KB969_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6869747.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            9797..10828
                     /locus_tag="KB969_001763"
     CDS             9797..10828
                     /locus_tag="KB969_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6869748.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            10917..11222
                     /locus_tag="KB969_001764"
     CDS             10917..11222
                     /locus_tag="KB969_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBB6869749.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            11401..13416
                     /locus_tag="KB969_001765"
     CDS             11401..13416
                     /locus_tag="KB969_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6869750.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            13418..13702
                     /locus_tag="KB969_001766"
     CDS             13418..13702
                     /locus_tag="KB969_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869751.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            13728..15101
                     /locus_tag="KB969_001767"
     CDS             13728..15101
                     /locus_tag="KB969_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6869752.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(15184..17199)
                     /locus_tag="KB969_001768"
     CDS             complement(15184..17199)
                     /locus_tag="KB969_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBB6869753.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(17221..18435)
                     /locus_tag="KB969_001769"
     CDS             complement(17221..18435)
                     /locus_tag="KB969_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6869754.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            18656..19600
                     /locus_tag="KB969_001770"
     CDS             18656..19600
                     /locus_tag="KB969_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869755.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            19896..20840
                     /locus_tag="KB969_001771"
     CDS             19896..20840
                     /locus_tag="KB969_001771"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBB6869756.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
BASE COUNT         7151 a         3870 c         3972 g         6025 t
ORIGIN      
        1 cttttttatc gatatttatc aactgtacat aagagtctcc agctttccat tcaaatggag
       61 ttccttggga ttctctcatg agatgcacaa caaaatacat aataaagaaa gattgctcat
      121 atgggctttc ttcctgaaac aaattcatct gacaattatt cttgaccata atttctttga
      181 tcttcttttt ttcgattgga aatggcaacg tgcgtcttcc gtagtaactt aaaaagaaaa
      241 aggtaacaaa gatacgcaac tggagctcac ttttaaggct agttaactga aaaccttggt
      301 caacgatcac ttttaataaa tagctttcta aaatttgatt gcattgtttc aacttacgtg
      361 taaaagaaga ccggctgatg gaaatttttt cacaataata ctcaatcgtt ttacccggat
      421 tgacaataat ctcatttaat aaacgactgt ttgtagaact ttgcgacatt tccatcagaa
      481 catttaaata agctggtaca ttcaaatgtt caagacgata ccccaatttt tgtgaagatt
      541 gaatcgttac atccgttccc cagcggattt tgatctcttc gatatacctt acaaatgtag
      601 attctgaact accaattcgt ttggcaagtt cttttttagt catccacttg tcagaaatgg
      661 acagaattcg aatgattttt tccatctttc tatagtttcc ttccaacaac ctgatcatat
      721 gtttttctcc ctcaaccctt ttctttcaat gaaacgctca ttaatcgaag gaatcaactt
      781 cataaatgaa accaattggt atgaaaattg gtgtgattcc ctttagcgcc cttcgtataa
      841 taattatcat attaaaataa ataaaattat gtaacgcctg tttattttaa taattttcac
      901 tattcacgtc aaaacagaaa aaaagaaaaa ggaggggaaa aatgacgacc acagggaaga
      961 aactgaaagt tattttcatg ctgataatat tgagtttatc aaactttgtg ccattatctg
     1021 caatagcaga cactacagat gatccaacag ttttagaaac aatttcagct gaagtcattt
     1081 cggatcagtc tggaaaaaaa gcactgaaca tcaagctaaa tgcgaataac accagtgctg
     1141 aaaagataga aaaagaaatt ggtctagtcg aaaattactt aagtgatgtg gaaagaaaag
     1201 aaggagatgg ctatgcttat caggtaaata gcgggaaaat tacgttggaa atctcatcaa
     1261 acactaaaca aactatcgat ctgagttttc caatcgatcc agcactttac cacagccagg
     1321 caaacaagct gatcgtcgat aataaagaat atgacattat tgatgagaca gaaaataaga
     1381 aagatacaga tgtgtcagta ccaaagccag acgaaataga agaagaatca tcaaaagaaa
     1441 acgaaaattc tgtcagccca tttacattgc ctacattatc cttgccagct gtgagtgtgc
     1501 catctaatca aacgattcct acagaatata caacagatga tcagggcact tatcctaaag
     1561 ccagttggca acctacagga aatacaaatg ttcttgatca tcaaggcaat aaaaacggaa
     1621 caaatcaatg ggatggtata aattcttgga atggagatcc taatgatcgg acccattcgt
     1681 atatcgaata tggaggaacc ggtaatcaag cagactatgc gatacgaaag tatgcaaagg
     1741 aaacaagtac acccggattg tttgatgttt atttgaatgc tcgtggaaat gtacaaaaag
     1801 atatcacgcc tcttgatctc gtattggtcg tagactggtc aggaagtatg aacgacaata
     1861 atcggatcgg tgaagtaaag attggtgtcg atcgttttgt cgatacttta gcagatagcg
     1921 gtatcacaga caaaatcaat atgggatatg tcggctactc aagcgaagga tatagctaca
     1981 gtaacggtgc agtacagatg ggttcatttg attcagtgaa aaatcaagta aaatccatta
     2041 caccttcacg gacaaatggt ggtactttta cacaaaaagc actaagagat gcaggaagca
     2101 tgctatccgt tccaaatgga cataaaaaag tgatcgtttt gctgacggat ggtgtaccaa
     2161 cattttccta taaagtacag cgggtacacg cacaatcaag cagcaattat tacggaactc
     2221 agttttctaa tacgcaagat cggccgggaa atacttctct aatctcaaga atctatgatg
     2281 cacctgacca aaacaatcta tccagaagaa tcgacagtac gtttatcgca accatcggag
     2341 aagcgatggc actcaaagaa cgaggaatcg aaatacatgg tcttggcatc caacttcaaa
     2401 gcgatccggc agctggtctc tcaaaagcag aagtagagtc tcgtatgcga caaatggttt
     2461 catcagatga aaaaggcgat ctttactatg aatcagctga tcatgcaaca gatatctctg
     2521 aatacctagc caaaaaagct gtacagatct cagcaactgt aagcaatgga caaataaatg
     2581 atccaatcgc agaaccattc atttatcagc ctggtacact ttcagtcaag agtgtgggga
     2641 caagtcctac aacggtcact ccatctattt ccatagaagg aaataccatc aagagcaatc
     2701 agatctattt aggaaaagac caagaaatcc aaatccatta ccaagtgaga atccaaacag
     2761 aaaatgagga cttccatcca aatttctggt atcaaatgaa cggcaggaca actttccagc
     2821 caaacattga taccaatgaa ttagctgaat tcggtatacc atctgctaaa gctcccggag
     2881 tcagtcttca catcaaaaag ttatgggaag aatttgacaa caatctagct gatcgtccag
     2941 atcaagttac ttttgagatt caacgggaac atacgacaaa tgctgcagct tggaaaaacg
     3001 gatatattcg aatcattaaa ccagctaaag atacaacaaa tacgtgggaa cgtgcagaca
     3061 ttgacaaatt atctgcaaat agcggagaaa gttatcaaga gatattatca ctacctcaat
     3121 acaataatca aggtcaagca ttcagttacc aaacaatcaa agaattacct gtaccaggat
     3181 acgattctca acaaatagat gcaatgacat ggaaaaatac taaacaattc acaccgttaa
     3241 acttgaaaat aacgaaaaat tcctctacag gtgaaaagga tcttattggc gctgttttca
     3301 aattaacagg agattctatt gatactttac taacagatca tggcgacgga acctattctc
     3361 ttccagaaaa tgtcaaattg caaaaagaaa tgacctatac gctgacagaa acaaaagctc
     3421 cagaagggca tggattaagc aaaaagacta cttgggaaat caagatcgct tctgatggta
     3481 cggtaaccat tgatggaaaa acagtcacta cttccgatga tacgatccag ttgactattg
     3541 aaaatccttt tgttgaagtt cctgtagcag tacgtaagta tgcgatgcaa gggacggaca
     3601 aagagataaa tcttaaagga gcagcatttt ccctacagaa aaaagaagca aatggtactt
     3661 atcagccaat tgacagccaa acaacgaatg aaaaaggtct tgccagtttt gattcactca
     3721 cacctggtaa atatcgagtc gttgaaacag ctggtcctgc cggatatgat acttcgccgg
     3781 gaaattatga attccaaatc gataaatatg gaaaaatcat ttacacggga aaaaataccg
     3841 agatgacaaa taatgtatgg acgctcactc atcaaaatcg actaaaagcg tttgatctaa
     3901 cggtacacaa aaaagaagac aacggacaga cattaaaagg agcaaaattc agactgcagg
     3961 gaccagaaat ggacttagaa tcgccaaaag atggacaaga aacagatacc tttctattcg
     4021 aaaatttaaa acctggaact tatacgctga ccgaaacttt tacaccagaa ggataccaag
     4081 gtctaaaaga gccagttact atagttatac acgaagatgg gtcaattcaa gtggatggac
     4141 aagatcatga atctgttctg tcaccaggag ccaaaaacaa ccagatttct ttagacatca
     4201 cgaatcaggc aaaagtacca ttacctgaaa cgggaggaat tggccgttta ggaatctatc
     4261 tagtagggat gattggttgt gcgttttcta tttggtatct ttttttgaaa aaagaaagag
     4321 ggggcagcta aatatgaaaa aacttggttg gcttagtatg tgtctcttct tgttactatt
     4381 taaaccagct tttactcagg tagcaacaga aacagaaaca gaaatggttc agattacttt
     4441 acacaaattg cttttcccaa acgggcaact gccgaaaaat catccaaatg acggacaaga
     4501 aaaagcttta ttacaaacgt atcgaggatt aaatggtgtc acattccaag tttatgatgt
     4561 cacagattct ttttaccatc tacgggaaaa gggcaaaacg gtagaagaag cacaagcaga
     4621 gatcgcaaaa aacggtgcgt cttccggtat gtttaccgca gaagcaacaa ctacaactct
     4681 taacaacgaa gatggtatcg cttctttttc tctggccgct aaagatcaag aaaaaagaga
     4741 taaagcgtat cttttcattg aatccaaagt accagaagtc gtcaaagaaa aggcagagaa
     4801 tatggtagtt gttcttcctg tacatggaca aaacaatcaa aaactttcaa ctatccattt
     4861 gtatcctaaa aatgaagaaa acgactaccc tgatccacct tttgagaagg tattagaaga
     4921 gcctagaaat gattttacga ttggtgaaaa aatcacttat tccttgcata cgacaattcc
     4981 tgtaaatatc cttgactatc aaaagttcga attgtcagat agtgcggatg aagcattaac
     5041 gtttttacct aatagtttaa cgatttcatc gaatggagaa aagctgacag aaggctttgt
     5101 catacacaag aaacctcacg gatttgatgt tttattttcg atcccttcgt tggaaaaata
     5161 tgctggaaaa aaactgacca tttcttatca gatgcagcta agcagtacag cacaggcgaa
     5221 caaggaaatc aacaacaacg gaacactgga ttttggtttt ggtgtcagta caaagaaagt
     5281 ctctgtatat acagggagta agcaatttgt caaaatcgag acaaataaac cagataaacg
     5341 attagctggc gcagtattcc ttattaaaaa caaagcagga aattacctcc agcaaacagc
     5401 caacggatac aagtggacaa agaacgaatc agatgcgctt cacctgattt ccgataaaaa
     5461 tggcgctttt tcaatttccg ggttgaaaac aggaagttat cgattaaaag agatcgaagc
     5521 accttctggt tatattttaa gtgaaacaga aattccgttt accatttcaa cttttctttc
     5581 tgaggataaa gaggcggaca gtatattgaa agtagtcaat aaaaaagaaa atagccgtcc
     5641 atttcttcca aaaacaaacg aaacgaaaaa tacactttta ggcgttgttg gtatggtatt
     5701 cgcaagcttt gcaatctggt tgtttatcaa aaaaagaaca ggagtgaaaa aatgaaaaat
     5761 cataaaaaaa taaacgttat gttaggagtc cttttcctta ttttaccatt actcacaaac
     5821 agcttcggcg caaaaaaagt gtttgcagag gagacagcag ctcaagtcat ccttcataaa
     5881 aagaaaatga ctgatttacc cgatccttta atccaaaaca gcgggaaaga aatgagcgaa
     5941 ttcgatcaat accaaggatt agccgatatt tcattttcag tttataacgt cactcaagaa
     6001 ttttatgcgc aacgagataa aggagcgtcc gtggatgcag caaaacaagc agtccagtct
     6061 ttgactcctg gtacaccagt tgcttcagga acgacagatg ctgatggaaa tgtcacttta
     6121 tctttaccta aaaaacaaaa tgggaaagat gcagtctaca cgatcaaaga agaaccaaaa
     6181 gacggagtgt cagctgccgc aaacatggtt ttagctttcc ctgtatatga gatgatcaaa
     6241 caagcagatg gctcttataa atacgggaca gaagaactag atactatcca tctctaccct
     6301 aaaaatacag tcggtaatga tggaacgttg aaagttacaa aaatcggtac tgccgaaaac
     6361 gaagcactaa atggagcaga atttattatt tctaaagaag aaggaacacc aagcgtcaaa
     6421 aaatacatcc aaagtgtcac agatggattg tacacttgga caactgatca aaccaaagcc
     6481 aaacatttca ttactggtca ttcttatgac atcggcaaca atgactttgc cgaggcatct
     6541 attgaaaaag gccagttgat cgttaatcat ttagaagttg gaaaatataa tttagaagaa
     6601 gtaaaagctc ctgataatgc ggaaatgatt gaaaagcaaa caatcacgcc ttttgagatc
     6661 ctggcaaata gccaaacacc agtagaaaag accatcaaaa atgatacgtc taaagttgat
     6721 aaaacaacac ctcaattgaa tggaaaagat gtcgcaatcg gtgaaaaaat tcaatatgag
     6781 atttctgtca atatcccatt aggtatcgct gataaagaag gaacgcaaaa caagtacaca
     6841 acattcaaac ttatcgatac tcatgacgct gctttaacat ttgataatga ttcttcagga
     6901 acgtatgctt atgccttata tgatggaaat aaagaaatcg acccagtaaa ttattctgtc
     6961 actgagcaaa cagacggatt cacggtttca gttgatccga attatattcc ttcattaact
     7021 cctggcggta cattgaaatt cgtttactat atgcatttga acgaaaaagc agatccaacc
     7081 aaaggatttt ctaaccaagc aaatgtcgat aacgggcata caaatgatca aacaccaccg
     7141 tcagtcgatg tcgttactgg gggcaaacga tttgttaaag tagatggtga cgttacatca
     7201 gaccaaacac ttgctggagc agaattcgtc gttcgtgatc aagatagtga cacagcgaaa
     7261 tatttatcga tcgacccatc cacaaaagcc gtcagctggg tatcggcgaa agaatcagca
     7321 acggttttta caaccacaag taacggttta atcgatgtga caggtctaaa atatggcacg
     7381 tactatctgg aagaaacgaa agcgccagaa aaatatgttc cattaacaaa ccgtgtagca
     7441 tttactatcg atgaacaatc ttatgtaaca gcaggacagt tgatttctcc tgaaaaaata
     7501 ccaaataaac acaaaggtac acttccttca acaggcggta agggaatcta tgtgtatatc
     7561 ggtgcaggag tagtccttct actgattgct ggactgtact ttgctagacg caagcacagt
     7621 cagatttagt ctttttgcaa gaattggaaa aaggagcagc ggattacgca aatgctcctt
     7681 tttcttttat tatcaaacag tcatcacaag gagaacacaa atgaaaccaa agaaaaggaa
     7741 acttctagat ctgctgatgc ttttcttgct tctctcagga atagggatac tagcttatcc
     7801 atttgttagc gacgcgctga ataattatct ggatcagcag atcatctctc attatcagca
     7861 acaagcggtc aaagaaaatg aagaagtcat ggctaaaatc caagaaaaca tgacaaagaa
     7921 aaaccagcaa ttagcaaaag aaggtggaaa tccaggtgca gatcccttta ctaagaaaaa
     7981 agaacctgcg aaaaaggata gaacctattt tgagaaacat acgatcggta ttttgacgat
     8041 ccctgagatc aatgtccatt tgccaatttt tgatgaaacg aatactgtgc tgctagaaaa
     8101 aggtgcctca ttattggaag gaacgtctta tcctacgggg ggagaaaata cacatgccgt
     8161 tatttccagc catcgaggac tgcctcaagc aaagttgttc acagacttac cgaaactgac
     8221 tttaggtgat tctttctata tcgaaatcaa tggacggaca ctcgcttatc aagtcgatca
     8281 gatcaagacg gtagaaccga ctgatacaaa agatctgaga atcgaaaaag ggcaggattt
     8341 cgtgacactc ctaacttgta caccttatat ggtcaacagt catcgcttac ttgtcagagg
     8401 gcaccgggtt ccttatcatg caaaagaagt tcaaaaagaa gtacagaaag tatccgagaa
     8461 caaacgattt ttcctgtatg gattgttagc tgcatgtata ctgattttcc tccttcttat
     8521 atatcttttt cgtcaatcgt tcaaaataag aaacagaagt tagctattcc tcatttctat
     8581 aatatatcta ttcgaatcgt tccgtaaaca aacaggctga ggtttgaaaa agaaaacttc
     8641 agcctgtttt tatgatgata tcaaagagag cctatcaaac actatctttc ttattactaa
     8701 atgaggatct tttcttaagt tttccgatat tctttaagaa ggcctttttg catcaattct
     8761 tgtttgtttt tcaagttgcg gatattctct tcaaaatttt gagaatatat cactgagaat
     8821 aacgtattta atacgtaatc gaaggcaatt tgagaggaga aagtcgctac tttagcaaaa
     8881 tcatattcct cctgcgatat aacaagacac atatcagcct gtttggccat ttctgaatgc
     8941 tgatttccgg taatcagcaa ggtaggggcc tctacatgct tcaaataggt cattattcgt
     9001 tcataatgat ggatgcgacc gctgtagcta ataaaaatgg cgcaatcctc gctagtcaaa
     9061 ttggctgcat tccaagaaga atcactgtat tcttcagcca tgatcaaaaa cttattcaac
     9121 ttgaccattt tattctggaa tttccttgcc gtgatttgag aatcaccttt tgcaaaaaga
     9181 aagattcgct gtgccttgtt caatacttta ccgatttgat ctaaatcttc atgttcaatc
     9241 tgcaattgtg ctttttttat tgactggatc gataaatccg ccattttctt tgcaatttgc
     9301 tgagtgctat cttcacttga aaaaggaaaa ttaggatcaa tcgtttgatt gaactgagca
     9361 atcaattgat gaacttcccg ccccagctcg aaacggaatt ctttaaatcc gctgaatccc
     9421 atttttttgc ataaacgaat gatagctgaa tgggaagtat acgtagcttt tgctaattct
     9481 tcaatcgtca tgtagactgc agcttcgata ttcctacgga tgtaatcgac aatccgtttc
     9541 tctgtcgtgg taaacaactc ttgttttgtt agtttttctt caataagcat gatctgacct
     9601 ccaaattcta tcttactgat aaacacttgg ttccgctact atctttttga tttttatcct
     9661 tactttgaac attaatttca ccaaaccgaa tgataacaag tgtttttctg aactttttta
     9721 ccagaatagc tattataaat actttctgcg cttttctagg atatactgaa aacatcaata
     9781 aaaggaggca ccactcatgc ttacaatcgc ttatcttggc aatggaaaga gtacaaatcg
     9841 ctatcatttg cctttttcaa gaaaacttac gaacaaaatc aatatcaaaa aaattttttc
     9901 cccatctgaa ccagtgtgga aaacattcga agacatcgaa tatactgatc agctgtctga
     9961 tctttgggat gatcctgaga tccaattagt tgtcatcact acacctagtc aatttcatta
    10021 tgaatatgga aaaatggcac tcgaacatgg taagaatgta ctagtagaga aaccttttgc
    10081 agaaacgtca aaggaagcag aagagttatt tgcattagca aaagaaaaag gtctatttat
    10141 ccaatgttac caaaacagac ggttcgattc tgacttcttg acagtccaaa aagtaatcga
    10201 aagcggaaaa ttaggggata ttttagaagt agaaatgcat tatgattatt tcagaccgga
    10261 agtaccagaa aatacgcatg aattttctac tgcgaacagc tatttatatg gacatgcttg
    10321 tcatacagta gatcaagttc tttcttattt cggcgaacca gatgatatca gctatgatgt
    10381 acgtcaactt ttagggaaag gacgaatgaa tgattacttc gatctggatt ttttctatgg
    10441 aaatatgaaa atttcgataa aatccagtta tttccgcatc aaagaacgtc caagtttcgt
    10501 cgtttacgga aaaaaaggga tgttcgtgaa acaaacaaaa gatcgacaag aagaacatct
    10561 gaaaatgttt tacatgcctg atcatgaaga ctttggtatc gatttgcccg aacattatgg
    10621 tgtattgacc tatatagatg aacaagggag ttatcatgaa gaaaaagtaa tttccgaggt
    10681 tggtgattac agccgtgtct acgaagggat ttacgagaca ttagttaatg gcgcagaaaa
    10741 agtcatcaaa gatgaagaaa caatcttaca aatgaaaatt ttggaagaag gaatcaaaag
    10801 cattcaagaa tcagaaggaa aaatatgaca tatttgtaag aatcgggttt gttttttgac
    10861 gcataaactg tcttattgta cgatgaaaaa gtatagaact actaggagga accaacatga
    10921 caaattatga cggtgaaaaa cacaaacgat taagaggttc aatggcccct aaaacagaag
    10981 aagaagtggc tttagcagga actaattctg gtgaaacaga agacaaagaa gaatcattag
    11041 ctggcacaaa ctctggtgaa acagaaaata aagaaacagc tttatctggt tcaaattctg
    11101 tagaagagga aacaaagcct aatgagccca atcactttga aaaagatatc gaaaaagcgg
    11161 ttgaagatgt caaagaaaaa tttgaagaac tgacctcaaa aaataaacat gatcatcatt
    11221 gatcggacga aatcaattca taaaagcagg agacatttgg tcacctgctt tttttctgta
    11281 tccattcgat agaaatcgtt cggtacagtc gtaaaaaaaa tccaactgta agttgtacca
    11341 aacacccctc gatttaaaag cgctaccata ctagaatata agtaggaggt gaacagcgct
    11401 gtgaactaca aaattagtta tctcctgaaa acaccaagag aaatcagtct agaaaaagca
    11461 gcagagatca tcgaagtaaa tacaagcgag gcgatcaaac aattaactcc ttttgccgaa
    11521 tatgtggatg atacccgtat ccgtataaag aaattccgag caatcgactg ggcagaaaaa
    11581 tttttggata ttactcgatt tgaagctgtg tataccgaac aagagcgaag agatcttctt
    11641 tatttgatgg tttattcgac tgcaacgtct gtttctgttt ttcattttca agattttctt
    11701 caggtttcta aagggacagt cctgtcagat atcaaaaaga taagaaatga attagaagtg
    11761 gaagattgtc agctgtcgta tactaggaaa actggtttta ggctgctagg gtcagaagca
    11821 atattaagaa gagaagcaaa aaatcgcact gctcgtttga tgcagtcact tgctggaaga
    11881 tttgggctca cgtatttaac cgcaaccctt tccattgatt attacgccaa agttagagat
    11941 ttgctagata aaacgatttc actatcagat cttcgattcg caccaaatcg aatggatgaa
    12001 ttagcttatt atttgagttt gacaaccatt cgaattggaa aaacatccat ggaactggta
    12061 aaagatgctg aactgttggc ttctcttgca gtcactgaca ttagtcgaca agtattgact
    12121 ggccttggct attccgaaca tcaaaattcg gagattatat ttttctctct ttgcttagca
    12181 tcgatcgttg aaggagatgt ccaggagcct gcacttgatt ttttgctgga atgttcttca
    12241 gaagtcatcc atcgcatgga attcctgatg gccgtagaat ttgcttcgtt tcgtgaatta
    12301 ttgatgaatg tcttttatca cttggtccct gcctattttc gtatttccta ttctttttat
    12361 ttacctaatg tgatgatcga tcaaattaag catcaatatg cttccatcta cgaaatgaca
    12421 agaaaagcat tacttccgtt agaaagacga atagggaaga gcatccctga agaagagatt
    12481 ggttttttca ctatactatt tggcggagag atcagaaaag cggacgcaga agaaagaaat
    12541 agaaaaataa gagccgtgat cgtctgtcca agtggcatta gctcttcatt gatcttaaaa
    12601 agtgaacttc agcaattatt cccgatgatc ttttttacag agactaattc agctgaccgc
    12661 ttacacgagg ttgacgaaac ttcttacgat attatttttt ctactgtacc tctcacactt
    12721 actgataaga aaaagtctct ctatgttctg catccaatca tgactgactt ggaaaaaaat
    12781 cagctgatca atcaagtaca aagagattgg ctgataccag gattttcaat gccttctgcc
    12841 caagaattgt tgtcggcgct actgccttat atcgaattaa aagaaggcgt agacgaagaa
    12901 aagctctatc aagtattaaa tcgtaaaatg aacaaacttt tagaaaagaa ggaggatcaa
    12961 cgtcctatgc tatctgaatt attaacagaa gaaatgatcc aattatcgga tcaaccaaaa
    13021 aactggcaag aagcaatcac atttgccgca cagccgctat tatcagaaaa taaaatagaa
    13081 gaaagttata tcaaagctat gatcgagcgc gtggagcagt atggtgcgtt tatccatatt
    13141 ggcgatcaca tcgcattacc tcatgctcgt ccagaagatg gcgtaaacga agtagggatg
    13201 tctttgctga aacttcaaca acctgtggat ctgcttgata atccagccca tcccattagt
    13261 ttgttcatct gtttagctgc tatcgataat gaggcacatc ttcgggcttt ggcaaattta
    13321 acaaagctac tttctaataa acaaaatctt caagatttat tacacgcatc aacaaaagaa
    13381 gaaatattag cgatcataag aaaaggagac gaatgatatg aaaatttttg cagtatgtca
    13441 aagtggatta ggaacaagtt ttatggtaga gatgaacatc aaacaagcac ttgcagatct
    13501 tggagcagat gtggacgagt ttgaagtaag tcatacggat gttggaagtg tatctagcga
    13561 tatggctgat tatttcttca ttgagcattc tttgaaagat acgctaactt ctatacctga
    13621 tgaaaagctc gtacctttgc aatcgatcat tgacagcgaa gaagtaaaag aaaaagtaac
    13681 gaagatcttg tcaaaagaat aaaaatgatt caagggagga actatcaatg gataaattgt
    13741 tgaatttgtt tgtgtcaatc gtcagtcagc cctccatcct cgtttctttg attgcactgc
    13801 ttggtctcgt tcttcagaag aagaaatttt cagaagtgat ccaaggaact atcaaaacat
    13861 ttgtcggatt cctagtactg atcggcggtg ctggtttaat cagtaattca ctaacccctt
    13921 ttgcttcgat gttccaaaca gctctgcata ctcaaggagt agttcctagc aatgaagcag
    13981 tagtggcgat tgctttgcaa caatacggta cacctactgc tttgatcatg ctagtaggga
    14041 tgatcgtgaa tattttactt gctagattca caagatataa attcattttt cttacaggtc
    14101 aagcaatgct ttatgtttct tgtctaacag cagtcatttt agtaagcgcg gggtttactg
    14161 caaatttgtg gatgatctta ttaggcgggg tcttcgaagg aacactatta actattacgc
    14221 ctgctctttg tcaaccgttt atgaagaaca tcactggaaa caatcaagtt gcgttagggc
    14281 ataccggaaa tatcggttat gcttctagtg gatggatcgg aaagtttttt ggaaacaaag
    14341 accgttctac agaggacata aagattccta aaagtttcag ctttttgcga gattctactg
    14401 tatcgatcat gctcttgatg tcgatcgtat atgtcgcact tgctttgtta gctggtcctg
    14461 gatttgttga aagagaacta agcaatggag acaacgctgt aatctttgca ctgatccaag
    14521 ctggaacatt cacagctggg tttgttatcg tccttcaagg ggttcgaatg gtgttggcag
    14581 aaatcgttcc agcattccaa gggattgcta aaaaactcgt acccgattct aaaccagcat
    14641 tagatgttcc tatcgttttt ccatatgcac ctaatgctgt attaattggc ttttttgtta
    14701 gcttctttgt aggaacacta tccatgtttg ctatgatagg cttgcaaact acagttatca
    14761 ttcctggggt agtaggacat ttcttctgcg gagctgcttc tggtgtcttc ggcaactcga
    14821 ctggcggtag aagaggggcg gtattaggtt ctgctttcaa tagcttattg attagttggc
    14881 tgccattatt tatccttcca gtattaggag atcttaaaat cgcttcttct acatttgccg
    14941 atactgatta tctagtacca ggacttgtac ttgggaaact aggagaatac ggtcaaatag
    15001 ccttgacagt tggaatcatc gctttctttt tacttgtcgt attatctagc tttctttttg
    15061 ccggaaaaag aacaaacatt gtttctaaag aacagaatta agcaaacttc aaaataaaaa
    15121 ttgcttggac aatatcagaa gaagatttaa agtcttctga tatgtcgcaa gcagtttttt
    15181 gttttatgca tttatttttg aatagcttgt taagacaagt ggctgttttg ctagaagagg
    15241 ataactttta ccattcattt tcactgttcc gcctgttcta tcagaagtaa tcacgatctt
    15301 atcttttgtt ttttcaagcg aaatctttcc atctttgata ggtagcgtac aattcagtgt
    15361 ttcaaatgaa tctagattag gttgtatcat aaattcttca taacctggct ttgttggata
    15421 caaaccgata aaatagcgtc ctaaaagata gattgggctt gctccccatg catggcataa
    15481 gctttttcca taaggatctc catacatact gtacttttca tttcctgttt gagtagggtc
    15541 gtattcttcc cagaaagtta ccgcatcatg agataacatc cctccccaat aatcaagaat
    15601 cgtttggtag acgatattcg tctgtccgag tttgcataaa gcatcttgtt catagaattt
    15661 gaaatatgga gtagtaatct gtgtgatagt gtcattcaat aagacattct ttaagatcga
    15721 ttgctgttgg tctttgttag caaaatcgaa taaaacagcg aaaatattcg catgacgcgt
    15781 cacatttctt ctcccagatt catagcaatc gataaaagcg ccaagttctt catcccaaaa
    15841 gtagtcaaat aggttttgtt tcaatagttg atatttttct tgatagagat gagtatgata
    15901 attttcgttc tctccatatg tttcagctaa gatatctccg caagtgatca tggaatgata
    15961 ggctttcagt aataagactt gttctgcagc aagcgttcct tctttatcca tttcagacca
    16021 atcaataaat atccaatctt ttgctctccc ataaataaac cctaattcat tcgtttgctc
    16081 catcaagtat ctcattaatg attgcatctt agggtagacg atgcgtaaaa attcatagtc
    16141 tttcgtcatc atatagtggt tttcgatacc aatcaaccac aagatcgaat agtcaacgat
    16201 agtattcata tgctgcttga tttcattttg tcctcttaat gctaatatcg ttcgtttatt
    16261 gatttcctcg tcaaaaaaaa gatattgatt gatcatgaat gattgatacg catctccaga
    16321 ccaaatccag cgatctcgtt tgataccgtc gataaaaaac aaatcactac ataacttgaa
    16381 ggcttcttct gatactgacc agatctgatt cagtaaagaa gaatcgcttg aaaaagcagc
    16441 ttgtttcgaa agagataaaa attcatgaaa aacttgaagt tgaaccattc cagtagaaac
    16501 ctctggtata aacaaatagc gaaaagcgcg tttacgagct ttcatttttc ttgtcattcc
    16561 tatttgctta tagtagcaat aatcgatatc catagcttct acatcggact ctccataaca
    16621 tagagtgata gattcgatat ggtcatccag agatattagt tctacacagc cattcactgc
    16681 tcgcccaaaa tcgaataaga ttcctccgcc aatctccgtt tcagtgactg gatggacgca
    16741 ttctttttga taatagattt gatttggatc ttttgcgata tcgacataaa gcggactcca
    16801 gccagctgga tattcttcaa taaaattact tgctgtccag ccaatatctg attttacttc
    16861 gtctccctcg ataaacatcg ctggtagccc tgatgtatgt cctacaaaga tacgaatttt
    16921 tgctttacca gctggacaag tcagccattt tccacatgga tgtttttgtc cattaatttc
    16981 tacataccca actccttgga tcgtcacttt aaacatggaa ggttgatcaa gaaagtaata
    17041 tctcttaaac ttgacgttcc gatggcaatc atccatgtac cagtacgctg gccagtcaaa
    17101 acctcgttct tcccgttgga aattttgtag cagtccatgg cggatctcaa agtctccagg
    17161 ataccaaagc catctatctt tatgtttttc atttgtcatt ttacacgacc tccatcaaat
    17221 ttattttgtt gtcaattgtt cttttatttc ttcatctact cttatcactg tctttctatt
    17281 cgtcctgtgt actactagaa ggctaataag cgcgctaatc aacagcaaga tactgccatt
    17341 gacgaaaaca gcaagtgttt tactcccaag agaagcaaaa gagagaaaga gcaaaccata
    17401 tggtgcaatg aaagtaccta aattagcgcc aaccaataag attgaagtat tgaaactctc
    17461 cgcgtacttg ggcgcttgga tacttacttg gttgaataag taaggaatga ataacgaaaa
    17521 agaaattcct gttaggatcg caccaaaccc aatcacatac aggtttatca cagtggcaat
    17581 caatacaaag ccgattccca tcagtagtaa agaaagtgta agcatatagc gatgtgcttt
    17641 tgtctgaagc cagccaaaac aaactccggc agccatactt gccaattgca tgattgttaa
    17701 gatattcgct gcattagttt cgtttcctag agaataagtc gtcaggactg tggctaattt
    17761 aatcgataca gcattatata ccacgatgac cagcaagaga aaaataccat aactaatcat
    17821 tttaggattc gttttgatta cttgtcttgt tggggctgtg ccatgcgatt gaagttcagt
    17881 tgtttcaggt gtaggaacaa acaaaacaaa caagacaaga ataggtaagc tgatggcgta
    17941 gactaaaaag gtatattgcc aaccgaactg tactagctgt cctgcaacaa atgtcattaa
    18001 agctgcacca aatccttgaa atgcactttg aaaaccaatc atagaggctc gttcatctcc
    18061 gtgataaaag gcagcaatca tgctgactgc caaagaattg atcaatccaa agccaatacc
    18121 tagtccagct cttgaagcta agacaatact gtaactttgt gagaagaggg ggaggatacc
    18181 acaaatcgat gcaatcacta atccgatgat cacagtttgt ttttgtccga ttttcctagc
    18241 aataaaacta ctaatcaaaa caaaaatagt gaccataaaa gagggagcag tcgttaataa
    18301 ttcaacagca gataaagaac gcgtggcata agtagctgac atactgggaa ttgcagacgt
    18361 gactgcacca gcagaagtca aaataagaga gactgacagc agagaaaatt tcatcatctt
    18421 tttattcata agcatgttcc tttcattttt gtaagcgctt atcaaaaata tagtatgaag
    18481 tggttattct ctcaatagcg gaatcacagg aagttcatgt cccaaccata gaaagtcttt
    18541 atgaaaccaa aaatagcttt gcatataata gcagtacagc gtgaactaat aagcgaaaga
    18601 aaccgcttac aaaaaggagg gagtcaattg gaactagctg aattagacat tttttttgcg
    18661 taacgaagaa tcaatcgaaa ctctgcagcg tgaacaagga atgaatatca atgatttaaa
    18721 cttagcttac catcttcaga caccgccaaa aatccaccga ggggatctat ttcaacaggg
    18781 aaatattcat atcagtaaac accgtcgata tgcggaagtt cccgagcata cacatgattt
    18841 tgttgaaatc aattatatgt atagcggtac atgtttacaa attattaatg gagaaaggat
    18901 agagatggaa gaaagtgacg tggtgatcat tgataaagaa gctactcaaa gaatcgaata
    18961 cacagggcaa gaggatattt taatcaacat cttattaaaa gaagaaacct tatctacaga
    19021 gatattgaat catttggcaa gcacaaataa tctactttct tcttttttga taaatgcatc
    19081 aaaagaaaaa ggggaacata cacaattcat tcattttcgc ggcggaaaaa caagtcgttt
    19141 gacgcatttg attgaaaata tgctgttgat ttattttgat acatacagtc ataagatccg
    19201 ttcgttaaat ctctatacat cactattact gatcgaattg actcatttat tagaacaaca
    19261 aagcttttca tcagcagatg gatgcgcaga aaatgagatg cttagagtat tagattatat
    19321 cgataagcat tttacttctt gtacgttaaa agaaacagca gctcattttg gctacaatcc
    19381 ggtctatctt agtaataaat tgaaaatgta ttttgatgct tcctttcaag aactggttct
    19441 aaagaaaaaa ttcgactttg cgttggaact gattcaagaa acgagttttt cgttggaaga
    19501 aatcgctaat cgtatcggat ataaacaaac gacttcttta ttcaaattat tcaagaagta
    19561 ttcaacatgt actcccaatg aatggagaaa taaacattaa gaagaaaatc tttcactaaa
    19621 gcatatgaag gaaaattgtt ttaggtgcga ttgctgtctt attatatcgt tgcagcgaat
    19681 ttttttggat ttattttcag ttctaaactt ttggttgtat tatcagggga tataggtgta
    19741 aacatttgtc atttatctgt tatgcgtatt caggaattcg tttccatcaa aaattataat
    19801 aacaactatt ataattaaca tgttgataaa atgaataaac aagactatac ttttcatgaa
    19861 agtaacaaat agttatgaaa aggagctgtt tattcatgaa aaaaacaagt cgtaaagtag
    19921 taatcgtcgg tacaggtttt gttggaacaa gtatcgctta tgcaatgatc aaccaaggaa
    19981 tctctaatga attagtattg atcgatgtga atcaagaaaa agcagaaggg gaagcattgg
    20041 accttttaga tggtatggct tggggcgatg aaaatgtggc tgtatggtca ggtggctatg
    20101 aagaatgtaa agatgctgat atcgttgtta tcacagctgg tatcaaccaa aaacctggtc
    20161 aatctcgttt agatttagtt aaaacaaatg cgtcaatcat gcgccaaatc gtaaaagaaa
    20221 tcatgggatc aggattcgac ggtattatcg ttgttgcttc aaacccagta gatattttga
    20281 catatatcgc ttggaacgaa tctggtctgc caacatcacg tgttatcggt actggaacaa
    20341 cattggatac aactcgtttc cgtaaagaaa tcgcattgaa attaaaagtt gacccacgca
    20401 gcgtccacgg ctatatctta ggtgaacatg gtgattcaga agttgctgca tggtcacata
    20461 caactgtcgg tggtaaacca gtgtttgaaa ttgtagaaaa agaccatcgt attgcccaag
    20521 atgaattaga tgtgattgct gataaagtcc gtaatgctgc ttatgagatc attgatcgta
    20581 aaaaagcaac ttactatggt attggtatga gtactgcacg tatcgtaaaa gctatcttga
    20641 ataacgaaca agctgtattg cctgtatctg cttatttaac tggtgaatac gacgaaaaag
    20701 atatctttac aggtgtgcca tcaatcgttg acgaaaatgg tgttcgtgaa gttgttgaat
    20761 tatcaatcaa cgaagaagaa aaagcaatgt tcagcaaatc aacaagtgct ttaagagaag
    20821 tattgaacac tgtattataa gaaacaatga atatgaacta aaaatcctaa aactgcttaa
    20881 cagctgaaat agctgttaag cagtttttta ttgatatcta ataggtaagc aaataaatag
    20941 aatggttaaa attaatcggt ccgaaaatgt atccgtacat atgaacatat gaaatttaat
    21001 ctgttgatta caataagc
//
LOCUS       DADVXV010000052        20841 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.053, whole genome shotgun sequence.
ACCESSION   DADVXV010000052 DADVXV010000000
VERSION     DADVXV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20841
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.053"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            51..1016
                     /locus_tag="KB969_001772"
     CDS             51..1016
                     /locus_tag="KB969_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBB6869757.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRPKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(1073..1303)
                     /locus_tag="KB969_001773"
     CDS             complement(1073..1303)
                     /locus_tag="KB969_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBB6869758.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(1389..2276)
                     /locus_tag="KB969_001774"
     CDS             complement(1389..2276)
                     /locus_tag="KB969_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBB6869759.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(2365..3588)
                     /locus_tag="KB969_001775"
     CDS             complement(2365..3588)
                     /locus_tag="KB969_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6869760.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(3605..4651)
                     /locus_tag="KB969_001776"
     CDS             complement(3605..4651)
                     /locus_tag="KB969_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBB6869761.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(4815..6542)
                     /gene="ptsP"
                     /locus_tag="KB969_001777"
     CDS             complement(4815..6542)
                     /gene="ptsP"
                     /locus_tag="KB969_001777"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBB6869762.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(6542..6808)
                     /locus_tag="KB969_001778"
     CDS             complement(6542..6808)
                     /locus_tag="KB969_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBB6869763.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            7287..9521
                     /locus_tag="KB969_001779"
     CDS             7287..9521
                     /locus_tag="KB969_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6869764.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            9669..9989
                     /locus_tag="KB969_001780"
     CDS             9669..9989
                     /locus_tag="KB969_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBB6869765.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(10194..10418)
                     /locus_tag="KB969_001781"
     CDS             complement(10194..10418)
                     /locus_tag="KB969_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBB6869766.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(10616..12196)
                     /locus_tag="KB969_001782"
     CDS             complement(10616..12196)
                     /locus_tag="KB969_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBB6869767.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(12597..13973)
                     /locus_tag="KB969_001783"
     CDS             complement(12597..13973)
                     /locus_tag="KB969_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6869768.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(14101..15219)
                     /locus_tag="KB969_001784"
     CDS             complement(14101..15219)
                     /locus_tag="KB969_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6869769.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            15361..15795
                     /locus_tag="KB969_001785"
     CDS             15361..15795
                     /locus_tag="KB969_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6869770.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(15873..16406)
                     /locus_tag="KB969_001786"
     CDS             complement(15873..16406)
                     /locus_tag="KB969_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBB6869771.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(16500..17678)
                     /gene="mutY"
                     /locus_tag="KB969_001787"
     CDS             complement(16500..17678)
                     /gene="mutY"
                     /locus_tag="KB969_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBB6869772.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(17671..18468)
                     /gene="recX"
                     /locus_tag="KB969_001788"
     CDS             complement(17671..18468)
                     /gene="recX"
                     /locus_tag="KB969_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBB6869773.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            18575..19957
                     /gene="rlmD"
                     /locus_tag="KB969_001789"
     CDS             18575..19957
                     /gene="rlmD"
                     /locus_tag="KB969_001789"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBB6869774.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(20131..20709)
                     /locus_tag="KB969_001790"
     CDS             complement(20131..20709)
                     /locus_tag="KB969_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBB6869775.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
BASE COUNT         6206 a         4230 c         3632 g         6773 t
ORIGIN      
        1 atttcaaaat ttgttatagt ctttttattc aaagcgtaaa aggagatcct atgttaaaag
       61 aaaaaatgaa aactctcccc atgctgccgg gtgtctatct tatgaaagac cgagatggta
      121 aggtcatcta tgttggtaaa gcaaaacggc ccaaaaatag agtaagcagc tattttcatc
      181 agaataaaca gcattcaaaa aaagtattac gtatgattca tcatataaca gattttgatt
      241 tcgtcgtagt agacacggaa ttagatgctt tattgctcga gtgtcaattg atccaacatt
      301 accgtccttt ttataaccga caaatgaatt atttcagtaa ttataattat gtacatatta
      361 ccaataaggg atttgtatta acagatactc ctacggctcg aacatacggg ccttttcgtc
      421 tctataaaaa aatgccgtct attttgcgta taatggaaga aacttatcaa atgccttggt
      481 tgtctgaaat tagtttgtta gctttgcgag tccagcttcc tgacctacag gaaatgactt
      541 ttgaacagaa aaaaaaggaa ctccaagggc tgtttcaagg ccgaaataaa aagctactga
      601 cttacttgaa aaaaagacaa caacatttca tctatcagtt gaatttcgaa aaagccggta
      661 tgcttcaaaa agatatcgaa ttagttactt attttattag acggatccag gaacaaaagc
      721 agtttttaag aacaccatcg ctcaccttca gcatgccatt agcagcagat gagagtcaga
      781 aaaagcacta cctcgtttgt tatggtcaac ttgcagaaac aatgattacc tctggtgacg
      841 tttctcctga cttctattat gaaaagaaag aagctcattt atctttgaaa cgtcaattgt
      901 caaaagaaga aatcgatcct gtacaaatct tgatcagtta ccgcaaaaaa ttagaaaaag
      961 aacagtttga aattgaactg ttaaacaaaa aagaagctga aaagcaacta aattagttgc
     1021 ttctcggctt cttttaggca tcttcaactt caaatgtcaa ttatcctaaa atttattgga
     1081 ttaagtcata gatttccatc gctacgatat cgatattatc aaattcgtat tgctgatgag
     1141 tatctgtttc agttaattca aatgtatcgg tcgctttatc ataagttact gtacacttct
     1201 ctacgccttc tttttcaaaa cggcgaactt gcagttcatt atctgctgac tcgaccatag
     1261 cctccagtcg ttttatgatt gcgactaatt gtgaatgtgt catcggaggt cctccttttc
     1321 ttatttctgt tatattgtat caaaagcata gcctacttgc attgattttc tctaaaaaaa
     1381 ctcgtttttt atgatttttt ttctggtatt tttccttcag gccaccaaag tttgatcaaa
     1441 gcttgggttc cgtcattctc aaaaccttta tctgccaact cttcatatag tttcaatgct
     1501 tgggtagttg ctggcaatac aagatccatt ttttctgctt cttctaatgc aatctttaaa
     1561 tctttgataa aatgtttgac aaaaaaacca ggtgtgtaat cttcttttaa aatacgagga
     1621 gaataattgc ttaaagacca gttagctgca cttccacctg aaagcgtctc aatcactttc
     1681 tttaaatcaa gtccgttttt ttgtgcatag acaagcattt ccgtcattcc tgtcatcgta
     1741 cctgcaatca tgatctgatt agccattttt gtatgctgac ctttcccagc agaaccatgc
     1801 aatgtaaatg tcgtaccaaa ttctttgaat aaaggcagta cttgatcata aacggcttct
     1861 tctccaccga ccatgatcgt cagtgtacca ttctttgctc ctaagtcacc accggatacc
     1921 ggtgcatcta acgcatctgc gcctttttct tttgctgttt ttgcaatttt ttctgccagg
     1981 cttggtgtac ttgtagtcaa atcaactaaa atatgtcctg agatatctgc agaaaaaatc
     2041 cccgactgtc catagtagat ttcttctaca tctttggggt aacctaccat tgtaaagaga
     2101 atattacttt gttctgctac cgcttttggt gtatctgccc agatagctcc ttctgttact
     2161 aaaggatcag cttttgcttt tgtccgatta tagacagcta cttcgtgtcc tgcttctagt
     2221 agatggcgtg cgacagcact tcccatgacg cctgttccga taaaaccaag tttcattttt
     2281 tcgacctcct aaaaatcaaa aatccttgct tctatgctag tatacgctag aaacaaggat
     2341 tttttcataa aaaatgtttg aattttatct tttaaatgaa tttaatttta ttttgattcg
     2401 ttcaatcgag tcttcttctt cttttcttcg catctcttct tcatgataaa caaccatgtc
     2461 ttgataaaat tcgatcatag cttcgccgaa atgtgtagat gaaatatcat aaagtttagc
     2521 ttctaaaact tttggatctt taggaacttc actggaaata taatcaataa gtgctggtgc
     2581 aaagtcttcg tcggtttcaa aagttttccc taatgaagga tgatcgaaca atcggttcaa
     2641 ataagcattt ccttccacga cacaaggtgt tccggctgcc atcgcttctg tataagtaag
     2701 cccttgtgtt tctgaagtag aagcactgac aaaataatct gccgctttat aataaagtgc
     2761 tacatcattg ttgtccactt ctcctgtgaa ctgcacaaat tcttctaact gcagttctga
     2821 gatcaattcc tctaactctt ctacataagg tccttttcct acgataacta atctggcgtt
     2881 aggataagcg gagatgacct gaggaaaccc attaatcaag gcttggatat ttttctcata
     2941 agaaatcctg cttaaagaaa gaatcatcaa atggttttcc tgaagaccta gtgactccct
     3001 taatttgctg atatcctgct gagtgatatc agaacgtttg aatttttcaa tgtcgatacc
     3061 agtaggaatc acgcgaagcg gtgctattac accatagctg cgtaatgtat caataacacg
     3121 ttcacttgga caaactacac ctgtcgtatg atttgcaaat aatctagaca agtattttac
     3181 atgggattgc ctgatcactt ttcctttacc gatataatga aggtagtctt catacatcgt
     3241 atggtaagta tggatcagag gtattttcaa cttcttagct accatcttcc caagtatccc
     3301 tgctccgaat tctgtatggg tatgaataag atctagttct agttctttgg caaccaaata
     3361 agcataccac atgcctctaa caacaactct tcgatccttg aaagaaataa atggtacact
     3421 tggcattcga atcacatctt tttccaactt atccgcatta ggatcggtcg ttgtaaaaat
     3481 atagacttca tgcccatgtc tttctaattc ttgttttaat gttttgatcg atgtagcaac
     3541 tccgctgact tgcggaaagt aggtatcggt aaaaaagccg attttcatgt ttttcgcctc
     3601 caaactagtc cttgacctga tttacttttt ttaatttgct agagactttt tcattcagta
     3661 cactttcgta tacattttta agttcttcac cgattttatt gatacttcgc tcttttgctg
     3721 tttgataacc ggcttgtgtc gtactcggta gttcttgatt ggtaatctgt tggatcagtc
     3781 ggataaattc ttcgtttgtc ttccccatat agcagttctt gctatcttct aaccagccat
     3841 tatacactgg aatatctcga acaagtacgt tttgtttgct tgctaaagct tctaaaacaa
     3901 cgatcccttc tgtctcttca taagaaggga aaaagaatag atctgcacct gaatacgcac
     3961 cttctatgat ctctccacga atgtaaccag gaaacaggac attttcagga tgatcttctt
     4021 ttacaatttt ccggatgttc cgaggaatcg agtacatggg aacatgacca aaccaaataa
     4081 atgtgtattc gggcatcttc ttagcaattt ctacgaaatc aatgattcct ttacgttcga
     4141 aaaacaaacc gacacaaatg attacttttt gatccggaga cagtttgaaa tattctctga
     4201 acttttgttc tttcattgga tcagggtgat atttctctaa gtcgatccca ttggaaatag
     4261 cttgaatcgg cacacggata ccatagcttt ccaacaactg ttttgaataa ggtgttggcg
     4321 tgatcagata gtccgctttt tggtacaatc ctaccagata tttttttacg ataggagaaa
     4381 gctggttcga tctgataaag gaatttcgga aatcttcctc tgtagaatgc gcatgataga
     4441 caactttttt tccttctctt ctggctttat tgaccatatt atgactattg attccgtatg
     4501 tattgatgtg caggatgtca taatcttctt tttcatctag tgtataagag ataccgactt
     4561 ccgtcagagc acgtttttga tgatcaagcg cacgcccgat tccagatttt gcaagcatct
     4621 tttcactttc aaaatataat aataccttca ccttacgtcc cccttcactt atatagtata
     4681 acatagccta caaactgtca ctcaaactta agccctattt ttgtctattc ttactgacaa
     4741 aaacgttttc ttaaaaaaga acaaaaaaac tggcgtagct cttttacaag ccacaccagc
     4801 ttttgatacg ttgtttattt tacatattca tgaacaagtt caacgacttc ttccatcata
     4861 tcgcattctt tcaatgcacg atcagcaagt tcagccattt tcgctgtgtc caagcgtttc
     4921 attaaactac gcgttttaag aatagatgtc gcactcattg agaactcatc tagacccata
     4981 cctactagca atggaacagc tgtttgatct ccagccattt ctccacacat acctgcccat
     5041 tttccttcag cgtgtgctgc atcaattaca tttttgatca aacgtaaaat tgatgggtta
     5101 tatggttggt acaagtaaga aacgcgttcg ttcatacggt ctgctgccat tgtgtattga
     5161 atcaaatcgt tcgtacctac agagaagaaa tctacttctt ttgcaaactt gtctgctaag
     5221 actgctgctg ctggaatctc gatcatgatg ccgacttgga tcgtatcaga tacttccttg
     5281 ccttcactta tcaatttttg tttttcttct tcaaagatcg cttttgctgc gcggaattct
     5341 ttgagtgtag ctaccatagg gaacatgata cgtaaattac catgaacaga tgcacgaagc
     5401 aatgcacgca tttgtgtacg gaacatttcg tcgccttgtt cagataaact gatacgcaat
     5461 gcacgatatc ctaagaatgg attcatttca tgaggtaatt gcagatatgg tagttcttta
     5521 tctccaccga tgtccattgt acgaacaact acaggttttc cttccatacc ttctaataca
     5581 gctttgtaag cttcatattg gtcatcttct gttgggaagt ctggagaatc catatacagg
     5641 aattcagtac ggtacagacc aactgcttct ccaccattat tatggacacc aactagatct
     5701 tttggtgttc cgatgtttgc agctaattca aaatgcttgc cgtcagctgt gacagtttct
     5761 gcatttttta atttttccca ttctgctttt tgtgctgcgt aatctgcacc tgctttttca
     5821 aattcagctt tttgttcatc tgtaggatcg atgattacat cgccttcgat cccgttgaca
     5881 gccaaaatat cgccttcttt gactttagca gtaatttctt ttgtcccaac gattgctgga
     5941 atttctaaag aacgtgccat gatagcagaa tgtgaagtac gtccaccaat gtctgttaca
     6001 aacgctttta caaaattgcg atctaattgt gctgtatcac ttggagtcaa gtcatgtgca
     6061 acaacgacca cttcttcgtt gatcattgat ggatttggta aagtaacgcc taataagtgc
     6121 gctaaaatac gtttagcaac gtcacgaata tctgcagcac gctcttgcat ataagcatta
     6181 tcttccattg cttcgaacat accgatatac atatccgtta cttcttttag cgctgattca
     6241 gcatttacgc tgttgtcttt aatattttgc ttgatttgac ctaccatttc tggatctgaa
     6301 agaaccatca aatgggcatc aaatacttgc gcttctgctt cacctaagct ttgcgctgct
     6361 ttttcacgaa tttgctgcaa ttcttcagta gatttagcta atgcagcatc caaacgagct
     6421 tcttcagccg cagtatcttc tactgttgcc ttactgaatg ttaaatccgg ttgaactagc
     6481 aggtaagctt ttgcaacggc tacaccgtca ctagcggcaa tcccttttag catttcaacc
     6541 attattcaga taagccttct ttcttcattg tttcaacgat tgctgccatt gcatcagctt
     6601 cgtcagcacc ttctgcagta atagtaacat cagaaccttg acctacacct aaagacataa
     6661 cgcccatgat tgatttcaag tttactgatt tacctttata ctctaagttt acatcagagt
     6721 taaatttgct tgctgtttgt actaatagtg tagctggacg agcgtggatc ccagtttctg
     6781 ctactacgtg aaattctttc ttttccatat taatcggtct cctttaagtg agtgttgttt
     6841 ttatgtgagg gttttctttt ttagtaattc agagaatcct aacaaatgcc accctttcat
     6901 ctgtaaagat taacattttt tttcgttaga tacaacagtt ttcattcaat ttcagataaa
     6961 agtattcaaa ttattccgga ttctttttca tccttttctt cacattttat aacaaacgtg
     7021 tttatttcct ttttcttgtc gctttctctt ctcctgacgt ttatcattct ttcctttgac
     7081 cctctttgtt ttcatatgaa acgaattact tgcttccctt tttattttta gtataataag
     7141 agtcaaaggt caggaatggt caatagagat ttcacctttt ctacctcata aatctcttaa
     7201 aaaactaggg gttattcttt tacctcatga aaaacgagat gtaaaatatg gatgtaccca
     7261 tttttgtgaa aggacgtgaa tgattcatgc tttgtcaaaa ctgcggcaag aatgaggcaa
     7321 cgattcactt gtatgccact gtcaatggtc agcggacaca actcgattac tgtcagagct
     7381 gttatcaaaa aatcaaaaat caacaaaatg gaggtctgac taatatggcc caaaatgatc
     7441 catttggatt tggcagtttg gacgatcttt tccgttccat gtctcgccaa atgcaacagc
     7501 aaggaaatta tgagcaaaca ccaccaacac aatttggcgg aaacaacaac ttcaatggtg
     7561 gtcagccacc tcaaggcaat acagaaggtt tattgggaga atacggaatc aatatcacag
     7621 aacaagcacg acaaggtgat atcgatcctg tgatcggacg cgatgacgaa atcaaacgag
     7681 tcattgaaat tttaaatcgc cgaaccaaga acaatcctgt cttgattgga gaaccaggtg
     7741 ttggtaaaac agcagttgtt gaaggtttag cacaaaaaat cgtagatggt gatgtaccgc
     7801 aaaaattaat ggacaaagaa gtcattcgtt tagatgtcgt atctttagtc caaggtactg
     7861 gtatacgagg acaatttgaa gaacgtatgc aaaaattgat tgaagagatc cgtcaagcag
     7921 aaaatgtgat cctattcata gatgaagttc acgaaatcgt cggtgctggt tctgctggtg
     7981 atggaaatat ggatgctggt aatattttaa aaccagcttt agctcgagga gaattgcaaa
     8041 tggttggtgc tactacctta aatgagtacc gcatcatcga aaaagacgct gctttagaac
     8101 gtcgtatgca acctgtacgg gtagatgaac caactgtcga agaaacgatc agtattttga
     8161 aaggtttgca aaaacgttat gaagactatc atcatgtaaa atatactgat gaggccatcg
     8221 aagcagccgc aactttatcc aatcgttacg tccaagatcg cttcttgccg gataaagcca
     8281 tcgatttgct agatgaaaca ggttctaaga aaaacttgac gatccaaatc gttgatccta
     8341 aaacaatcga gaaaaaactg caagaagcag aagaacaaaa agttttagct tctcgagaag
     8401 aagatttcga aaaagcagct tattatcgcg atcagatcaa taaacttcaa aaaatgaaag
     8461 aacgtcagct cactgaagag gaaacacctg tgattaccga aaaagatatg gaaaaaatcg
     8521 ttgaacaacg gacaggtatt ccagtgggtg aattaaaaga aaaagaacag acacaactga
     8581 aaaacttagc agatgacttg aaagctcatg tcatcggaca agataacgct gtagatcgag
     8641 tagcgaaagc gattcgccga aaccgtgttg gattaaacaa acagaatcgt ccaatcggct
     8701 ccttcttatt tgttggacca actggtgtag gtaaaacaga gcttgcgaaa caacttgcct
     8761 acgaactatt cggttcacaa gattcaatga ttcgtttcga tatgtctgaa tatatggaaa
     8821 aacatagtgt ctctaaattg attggttctc ctccaggtta tgtcggatac gaagaagctg
     8881 gtcaattaac agaaaaagta cggagaaatc cttacagtct tgtcttgtta gatgaagtag
     8941 aaaaagctca tccagatgtt ttgcatatgt tcttgcaaat cttagatgat ggtcgattga
     9001 cagatgcaca aggaagaacg gtcagcttta aagatacgat catcattatg acaagtaatg
     9061 ccggaactgg taaagtagaa gcaaacgttg gttttggtgc ggcacgcgaa ggtgttactc
     9121 gttctgtatt gaaccaatta aacaactact ttacaccaga atttctgaac cgttttgacg
     9181 ggatcatcga attcagtgca ttatcaaaag aaaacttgat gacaatcgtc acactaatgc
     9241 tagacgatgt caaccaaatg ctggcagcac agcaacttca catcgaagtt cctacgaatg
     9301 tcaaagaaaa attagttgac ttaggctatg atccatctat gggtgctcgt cctcttcgac
     9361 gcacgatcca agaacaaatc gaagatggta tcgctgaatt ttatcttgat cacccttcta
     9421 tccatgagtt gaaagcaaaa ctggataaag atggaaaaat catcgttact tctaaaccag
     9481 aacgtttggc taaagaatca gccgaagaaa cggctgaata aatccagttt tatagcgtga
     9541 gacggtattt ctttgagaaa tgccgtctca ttcttttttc agaaaagtca aaatactgtt
     9601 cattttataa aaaagaaatt ataataagag aaacaagcaa ttaaaaatac ataaaagagg
     9661 tgagcgccat gaaattggta aatgtaacaa acagccattc ccgtcttgta ttaaaccagc
     9721 ttgaaaacac tgatgcccat ctagtcaagg tctacacagc cggaaatacc actattgtct
     9781 acactgaagc ccctgaacat aatgaaattc tgctgatcaa tgacaaacgt aaaatccagc
     9841 cgaaagaaat cgaagatgct aaaaattatt tcttagataa aatcaaagac gccgtttacc
     9901 acgaggatga aatcaaagta atcgaattgg caggccttgt tgaaatctcg attccaaaac
     9961 atgaattagg cgctacatta gccgtgtaaa caaattttga acataataat taaagagcgt
    10021 gggacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca
    10081 gaagcaactc cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga
    10141 attccagctt atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt
    10201 tttgattttt ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct
    10261 ttatttttaa ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg
    10321 tttttgtccc agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc
    10381 tgtttttttc tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta
    10441 atcatatgta cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat
    10501 atagtaaaaa gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg
    10561 tttttgtttg gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca
    10621 tcaaactttt taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt
    10681 tctcgaataa gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac
    10741 tcatcttctc atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag
    10801 acatgattac ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta
    10861 gctgaccaac agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg
    10921 ctccttcttg aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt
    10981 ttgcagtcac tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt
    11041 ttagttttcc ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga
    11101 tgatatcgcc tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga
    11161 cattgcttaa tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga
    11221 atgttccaga acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg
    11281 cttggatctt gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat
    11341 cttgtgtttt gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct
    11401 gtacaccgaa gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa
    11461 ttttttcttg attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt
    11521 gttcatataa ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca
    11581 attctactaa tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt
    11641 agatatcata aagaccttct agccctttac ccataccgat tggccaattc atcggataag
    11701 attcgatatc taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac
    11761 gatctagttt gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata
    11821 atttctttgt ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca
    11881 cggccatcaa agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga
    11941 tatttactcg tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac
    12001 gttgtttctc gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta
    12061 cggtcccggc ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt
    12121 tcccagcatc cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta
    12181 attttggatt attcataacc taactccatt tcttccattc aattatttat attttctcta
    12241 ggcacagatt gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc
    12301 gtgtagcagt ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc
    12361 ccacccaagc caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca
    12421 ggatagcttt ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca
    12481 gcgaatgaaa aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag
    12541 aaaagacgtg ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat
    12601 cttcttggct cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc
    12661 gcttctgttt cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc
    12721 atttcttcag aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc
    12781 ggaatcatgc ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc
    12841 agatcactgt caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat
    12901 tcgtgttcat cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct
    12961 ccgacgattt cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca
    13021 tctaataaaa tagccatctg attctgcgtc tttttcattt catataacag atcatcaata
    13081 aagaccgttt caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca
    13141 aagccgaatt tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta
    13201 tctttgtctt cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca
    13261 ttttcttcca cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact
    13321 tctcgggcaa ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta
    13381 ttcaatacgc cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct
    13441 tcatcatcaa aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc
    13501 cagacgaagg gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg
    13561 acttcttctg atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat
    13621 acataggtca aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca
    13681 cctaataccg gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg
    13741 ttgaccaaag tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt
    13801 tttaaaagct tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta
    13861 ttgatcgaaa caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg
    13921 atcaataata aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca
    13981 ttctctcctt ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca
    14041 cgttaaaatg gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac
    14101 ctacgaggtc gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt
    14161 gattatatag gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc
    14221 aagcaatccg gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat
    14281 tttcagtgat ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat
    14341 tagcacaacc acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa
    14401 tgcaggtgct agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat
    14461 gaccccaaat aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt
    14521 accaacgaat aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag
    14581 ttgccccaat aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt
    14641 tggcactagt ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat
    14701 tactacggtt gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact
    14761 aaggaattgc tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat
    14821 atctacttcc ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt
    14881 gatgaaatca ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac
    14941 actaagtaaa atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca
    15001 tattcttttg atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag
    15061 aaagcctgca atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa
    15121 aataaagttt atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga
    15181 ccaaaacatt agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct
    15241 tactagtata tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt
    15301 gccatacttt ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc
    15361 atgaaagttg tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc
    15421 aggcatcaag tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat
    15481 gaagcccatt gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta
    15541 cgtcttttgc ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa
    15601 tacagacacc aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat
    15661 caaggctata atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa
    15721 ctaggatata cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg
    15781 aaaaagactt tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa
    15841 atctctcact ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg
    15901 ttataccaaa tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca
    15961 accagaatct tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt
    16021 ttgctgtgca tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc
    16081 ttgatatcca agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa
    16141 gctagattac aataatagga aacccccttt tctctgatca ttgctattac attgaaccag
    16201 tattttttat gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat
    16261 tcagtgacta atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc
    16321 atggtatctc gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca
    16381 aactctcctt cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg
    16441 tgtttgggtg ttcattacac cgacatcata attattatat caataaaaat gagctttgcc
    16501 tagaaaggat tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc
    16561 ttaggaaaaa cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg
    16621 gtaaattctt gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc
    16681 agatgactaa aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc
    16741 tgcttttcaa atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt
    16801 tctggctttg tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc
    16861 attggaaatg tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac
    16921 gctccagaat gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt
    16981 tttgttttta caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg
    17041 atcggacaag tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc
    17101 attgcttggt tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca
    17161 aagattttcc tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact
    17221 actcgcatca cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc
    17281 gcgcctgtcg tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc
    17341 atttccccat caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt
    17401 gagtaataac caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc
    17461 tcttcaattg taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact
    17521 ctggtttgct gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc
    17581 caaggcaggt ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt
    17641 gtttctttat ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat
    17701 gaatcgctgg atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag
    17761 atttcttttt ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac
    17821 taaataatca tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg
    17881 gatcacttct tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc
    17941 tttttggctt tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg
    18001 aacttggtct tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc
    18061 tttttgctgc atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt
    18121 gcgcacataa ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc
    18181 tacgatttta tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc
    18241 tttttccgat cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc
    18301 tccgctactc ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa
    18361 tcgatagcgt actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac
    18421 gcgatagaaa gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct
    18481 cgaacatata ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga
    18541 ataaaccaca gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg
    18601 acaaacggtt cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt
    18661 caaacggttg atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat
    18721 cacgaaagca actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa
    18781 agatcgcgta gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca
    18841 cttagcttat caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa
    18901 attcaaacca gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc
    18961 ttggcattat agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat
    19021 tgaagctggt ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt
    19081 tcaagaacct cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga
    19141 tgcacccatc tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat
    19201 cggtgttaaa actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca
    19261 aaaaaacgca atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca
    19321 aaatgtccag gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg
    19381 aaaagaagcc attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt
    19441 ctttcaactc aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga
    19501 tgtccagcct aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag
    19561 tgtagcaaaa caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga
    19621 tgcaaaaaaa aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc
    19681 agagcaagtt ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga
    19741 tccaccacgt acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa
    19801 aaaacttgtt tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag
    19861 taaaaagttc aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg
    19921 tgaagttgtc gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc
    19981 tgccctgtat caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata
    20041 ctgtacttgt gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga
    20101 catagttttt gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata
    20161 aaatgcattt gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg
    20221 atcctgcgga agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc
    20281 tatttttgtg atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg
    20341 tttggtaatg tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat
    20401 atttaatgtt cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa
    20461 aggctcaaag ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt
    20521 agcttcgata ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc
    20581 tgctgatgtt cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc
    20641 tggaatgcta aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat
    20701 ctttttcatg tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta
    20761 acacaaacat tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat
    20821 gcagattata acagaagtag a
//
LOCUS       DADVXV010000053        20326 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.054, whole genome shotgun sequence.
ACCESSION   DADVXV010000053 DADVXV010000000
VERSION     DADVXV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.054"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            15..314
                     /locus_tag="KB969_001791"
     CDS             15..314
                     /locus_tag="KB969_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869776.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(411..845)
                     /locus_tag="KB969_001792"
     CDS             complement(411..845)
                     /locus_tag="KB969_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6869777.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1077..1787)
                     /locus_tag="KB969_001793"
     CDS             complement(1077..1787)
                     /locus_tag="KB969_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBB6869778.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1777..2637)
                     /locus_tag="KB969_001794"
     CDS             complement(1777..2637)
                     /locus_tag="KB969_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBB6869779.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2642..3280)
                     /locus_tag="KB969_001795"
     CDS             complement(2642..3280)
                     /locus_tag="KB969_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBB6869780.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3295..3594)
                     /locus_tag="KB969_001796"
     CDS             complement(3295..3594)
                     /locus_tag="KB969_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869781.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3637..5121)
                     /locus_tag="KB969_001797"
     CDS             complement(3637..5121)
                     /locus_tag="KB969_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBB6869782.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5141..5602)
                     /locus_tag="KB969_001798"
     CDS             complement(5141..5602)
                     /locus_tag="KB969_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6869783.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5620..6687)
                     /gene="ulaG"
                     /locus_tag="KB969_001799"
     CDS             complement(5620..6687)
                     /gene="ulaG"
                     /locus_tag="KB969_001799"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBB6869784.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6905..7675
                     /locus_tag="KB969_001800"
     CDS             6905..7675
                     /locus_tag="KB969_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6869785.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7948..8775)
                     /locus_tag="KB969_001801"
     CDS             complement(7948..8775)
                     /locus_tag="KB969_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6869786.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9343..10578
                     /locus_tag="KB969_001802"
     CDS             9343..10578
                     /locus_tag="KB969_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBB6869787.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11577..11837)
                     /locus_tag="KB969_001803"
     CDS             complement(11577..11837)
                     /locus_tag="KB969_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBB6869788.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(11864..13165)
                     /locus_tag="KB969_001804"
     CDS             complement(11864..13165)
                     /locus_tag="KB969_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6869789.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13457..13915)
                     /locus_tag="KB969_001805"
     CDS             complement(13457..13915)
                     /locus_tag="KB969_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6869790.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(13928..15259)
                     /locus_tag="KB969_001806"
     CDS             complement(13928..15259)
                     /locus_tag="KB969_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBB6869791.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15270..16712)
                     /locus_tag="KB969_001807"
     CDS             complement(15270..16712)
                     /locus_tag="KB969_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6869792.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(16699..17463)
                     /locus_tag="KB969_001808"
     CDS             complement(16699..17463)
                     /locus_tag="KB969_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBB6869793.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17567..18442)
                     /locus_tag="KB969_001809"
     CDS             complement(17567..18442)
                     /locus_tag="KB969_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6869794.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(18697..18781)
                     /locus_tag="KB969_001810"
     tRNA            complement(18697..18781)
                     /locus_tag="KB969_001810"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18745..18747),aa:Leu,seq:caa)
     gene            complement(18799..18870)
                     /locus_tag="KB969_001811"
     tRNA            complement(18799..18870)
                     /locus_tag="KB969_001811"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18836..18838),aa:Gln,seq:ttg)
     gene            complement(18880..18952)
                     /locus_tag="KB969_001812"
     tRNA            complement(18880..18952)
                     /locus_tag="KB969_001812"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18917..18919),aa:His,seq:gtg)
     gene            complement(19014..19098)
                     /locus_tag="KB969_001813"
     tRNA            complement(19014..19098)
                     /locus_tag="KB969_001813"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19062..19064),aa:Leu,seq:caa)
     gene            complement(19119..19189)
                     /locus_tag="KB969_001814"
     tRNA            complement(19119..19189)
                     /locus_tag="KB969_001814"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19155..19157),aa:Cys,seq:gca)
     gene            complement(19235..19306)
                     /locus_tag="KB969_001815"
     tRNA            complement(19235..19306)
                     /locus_tag="KB969_001815"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19272..19274),aa:Gln,seq:ttg)
     gene            complement(19318..19390)
                     /locus_tag="KB969_001816"
     tRNA            complement(19318..19390)
                     /locus_tag="KB969_001816"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19355..19357),aa:His,seq:gtg)
     gene            complement(19393..19466)
                     /locus_tag="KB969_001817"
     tRNA            complement(19393..19466)
                     /locus_tag="KB969_001817"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19432..19434),aa:Trp,seq:cca)
     gene            complement(19473..19553)
                     /locus_tag="KB969_001818"
     tRNA            complement(19473..19553)
                     /locus_tag="KB969_001818"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19517..19519),aa:Tyr,seq:gta)
     gene            complement(19555..19630)
                     /locus_tag="KB969_001819"
     tRNA            complement(19555..19630)
                     /locus_tag="KB969_001819"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19595..19597),aa:Phe,seq:gaa)
     gene            complement(19666..19738)
                     /locus_tag="KB969_001820"
     tRNA            complement(19666..19738)
                     /locus_tag="KB969_001820"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19703..19705),aa:Asp,seq:gtc)
     gene            complement(19748..19820)
                     /locus_tag="KB969_001821"
     tRNA            complement(19748..19820)
                     /locus_tag="KB969_001821"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19785..19787),aa:Val,seq:tac)
     gene            complement(19836..19907)
                     /locus_tag="KB969_001822"
     tRNA            complement(19836..19907)
                     /locus_tag="KB969_001822"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19872..19874),aa:Glu,seq:ttc)
     gene            complement(19922..20011)
                     /locus_tag="KB969_001823"
     tRNA            complement(19922..20011)
                     /locus_tag="KB969_001823"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19975..19977),aa:Ser,seq:gga)
     gene            complement(20051..20124)
                     /locus_tag="KB969_001824"
     tRNA            complement(20051..20124)
                     /locus_tag="KB969_001824"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20088..20090),aa:Asn,seq:gtt)
     gene            complement(20134..20249)
                     /gene="rrf"
                     /locus_tag="KB969_001825"
     rRNA            complement(20134..20249)
                     /gene="rrf"
                     /locus_tag="KB969_001825"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6345 a         4316 c         3235 g         6430 t
ORIGIN      
        1 aaaggaaata aaacatggat tatactgttg aatttgacag tgaactactt aagcaatttc
       61 cacaagaaga acatttcatg tataaagaag caatttccca caaagtgaca gagtatttgg
      121 agcataattt ttttcgtata aagccagtgc gtactcgttc ggcaaaagga atatacgaga
      181 tgaaagtcaa aattaataaa aaaaattatc gcatagcatt tgctttaaaa aaaaatcatg
      241 tgttcatttt ttatattagt tcgaatttgc aaaaaattgt atttgataaa gaggtgagta
      301 aaaaaataaa atagctgagc attggaggat agattgagtg atactaagtc tatcctcttg
      361 tttttctaaa gaactaagct agaatttttt cttttgtacg ttattatatg ttatttgtca
      421 ttaccaaaaa gcaccttttt tcttctagta tctatgacat aagaaatacc acccatttcc
      481 tttacttgaa caaatcctac tgattcataa aatttttttg ttttctcagt atcatctgtc
      541 aataattcga tttggactgg tccataacta gtgatcttct ccaaagcttc attcaaaagc
      601 actttgccta ttccttggcg ctgatacctc ggatgaatga ggatatcttg aataaatgcg
      661 atcgtcgcaa aatcagtgat ccaacgaacg attccgataa tcttcccttc cccattacgc
      721 tttatcagag attcagattg ttcaaatgct ctagctaacc ttgcagtgtc ttttgtgtaa
      781 ttcgtccaac caacgctctt atataattca gaaatctcat cgatcataag ggaatcaata
      841 ttcatttttt tcttcctttc ttatacaatt ctccctctaa taatacagtt ctttgactat
      901 ttaatctatc acatataact ctcctgtaaa gattctctcg attccttaaa attcctcttt
      961 ccttttagaa tgcatacttt ttgataaata aaaaggttgt gataaatttt cttcacaacc
     1021 tctgtttctc tctatcaagt gttatctttt aattttctac ccttacccta gcatctctat
     1081 tgcccgtagt atgcatactt tccatgtttg cgaaaataat gtttatctag taaatattgc
     1141 gggatttcac atatattggg gttgatcagc tcgttttctt tggccatcag acaaatttca
     1201 tctaagatca aactgttttc tactgctttc ataggtgaat ccccccatgt gaacggtcca
     1261 tgtccataga caagtactcc agggacttcg tttggatcta attttctttc cttaaacgtc
     1321 tcgacaatca cattccctgt atgaacttcg taagcttctc ttacttcttc tttcgttaat
     1381 tggcgtgtac aaggaacctt accataaaaa gcatcagcat gagtcgtgcc ataagctggc
     1441 aaatcgcgtc ctgcttgcgc ccacatgacg gagtgcgtgg aatgagtatg agtaatagca
     1501 gttatatctt caaaagtttg atacaaaaca acatgtgtgg ggagatctga agatggtttt
     1561 aagctatctt cttctattat atttcccgac aaatctgtta ccaccatttg atctgcttgc
     1621 atgcattcat atctgacacc gcttggctta atgacgatga ctcctagctc acggtccact
     1681 tcactcacat tgccccaagt caatttgact aatccgtatc gcggcaatgc cagatttgct
     1741 tcaaggacac gttgcttcat tgctgcaatt ttttcttcac aagacatcat agccagcctc
     1801 cttcaattta gaacttaagt agtcttttgc ctgctggatt tctcttcgaa agtcttggct
     1861 tttttcactc cacatttcaa tcagaaatgt tccatcataa tctagacgtt tcaaatgtct
     1921 taataatcca agaaaatcaa cacaaccgct accaaaagga acatcacgaa actggcctga
     1981 atattctttt gttacagggt aagtatcttt taagtggata gcagtgatat aatcgatccc
     2041 tttctcaagt tctcgagccg gattattttc cggccatgcg gacaaattgc ctaggtctgg
     2101 atatacttgt agaaaaggtg aatgaatctg ttctttgatt tctaaaaatt ttgaaatgga
     2161 gttcataaat ggatcatcca tgatttccac ggaaagaatg atgccatatt tagaagcttc
     2221 ctttacgctt tcttttattc cttcgataaa gtcttctctg gaattcattg atttctcttc
     2281 ataataaaca tcgtatccag ctatttggat tactttgacg cttagattat gcgccaaatg
     2341 gattgctttt ttcattagtt gtttcgctgc ttttttcttt tctggatcag cagaaccaaa
     2401 cggaaatcgc cgatgcgcac ttaaacaaat cgaatggata cgtacaccgg agctgaacat
     2461 ctcttctctc agctcagcta tcttttcttc agaccaatct aatcgtgcta accgctcatc
     2521 cgtctcatca atcgacatct cgataaaatc gaagtccatt tcttttacaa gggaaaaacg
     2581 ttctttccat gaaatatctt tgggtaacgc tttttcataa atcccaattt gagccatttc
     2641 cttaccccca gatacgaatg atctcatctt tgaagttttg tgcggccttc atcggatcat
     2701 ttgctgctgt aataccacga ccagtgataa aggtatacac atcgatccct tcaaataagt
     2761 gtaatgtgtg tggatttaat ccaccagtta cagaaacatt aaagcctagt tcaatcagtt
     2821 ttttgatctt cgataaatct ttttcacccc aagtttcacc agataacagc gcatcacggc
     2881 tttgatggta gattacctgc cggataccga tgttatgcca atccatggct tgttcaaaag
     2941 tccaattgcc gtagagttct acttgcaatt cacctatttc tttttgtgct gcctccatag
     3001 ttggaatcgt tgcacaacaa atgactgtca tccagtctgc tcctgctttt gcaacattac
     3061 tcgccactgt tcctccagcg tctgcacatt tcgtatcagc gactagtttt ttatctggga
     3121 acatactgcg aatacagcga atcgcttttt gtccttcctg taagcaaaga attgtgccca
     3181 cttcaataat atctactaca tcaccaactt tcataacatc tcctaatgca tgttctaagt
     3241 cattgtgatc taacgcaatt tgcaaattcg gcctgctcat cttagttcct tcctttactt
     3301 gtttttttgg taccactttg tttcagcaaa tttttcactg atttctttga ctgacatcac
     3361 atttttgata ccgataactg taactccttt tttctctgcc tgagtaaaca tattcaaaaa
     3421 attgactggc gtaaaaacta catcgtattg gccagctgaa ctttttccct ctgaaatggc
     3481 acaatgatgg attttggtaa ttggtacgtt tagttctttc attgcttttt ccacacttct
     3541 catcatcatc aagcttgttc ctgatccatt tgcacacgat actaaaattc tcatcttaat
     3601 ccctccatta tgagtgttgt ctaatcagat tttcttttat actctctgct tttctgcata
     3661 tgtgtcatag tcttctacaa tcaaaaaata accatcagga tttttccgat attgtaactg
     3721 cggaatagcc aataaaccaa tgacaactac ggcaattcca gcataaccta ggactttcat
     3781 gattactgta aacaatggcc aagctgttgc ccagtcgaac atcccgatat aaccaccgta
     3841 tgttgacatc ccaatccatg tagcgaataa tgctgaaccg cctacttgta tgattcctga
     3901 aagaaacggg aacaggcaag cggctttgaa tccacctcgg ttattggcat aaactgctat
     3961 aacggcatta tcaaagaaca acggaatgaa accggctatg acgatcgttg gtgatttcaa
     4021 taaaatcagt aaaccaatca tcaaaaactg tcccaaagca ccaaacaaga acccaatcgt
     4081 taccgcattt ggcgaaccaa agccaaaagt agcagctacg tcaattcctg gaacagctcc
     4141 tggtaaaatc gtgtttgaga ttccttggaa agattgagtt agttcatcga cgaatgtccg
     4201 aacacctaat tgcaagatcg ccagatatac cgcaaaattt aaagaagtcg tcataatgta
     4261 gaataagaaa ctctgccctt cttgcatgaa ttgcgcttga atcaaataat ctttgcctag
     4321 tacaatcaga atgatcccaa agaaaaatag catgagtaac gaagtagcaa ccatattctc
     4381 attgaaaatc gacaagaatc ctggtaattt gatatcttca atttttttgt cttgcttgat
     4441 tgatctattt ttcttttcat cccgcttttt catccactca gctaattttg caaatataaa
     4501 gattccgaac atttgctgat gtgccactgc aaatccggca ccttctgtca attcctgcgt
     4561 gattcctact gttaagttag aagctactgt ccaataacaa cctaaaatca gtcccataaa
     4621 aatcaatgct tgtatcctac ctagatcagg aaagcaaaac agtaaaatcc aaaaagcggt
     4681 agctgcttgt tgaacctgaa cgtttccggt agtgaaaacg gaacgcagtt tcgtatattt
     4741 ctgaaaacgg actaataaga tatttaaaac aaatgcaatc agtaataaaa tcatcacatc
     4801 tccaaaggta cggccaaatg tctccattaa tccagcatcc acagcatttt gtccaaaata
     4861 aggatctgta accatggcat ccaaattgaa ccgttccttt agtccaacca agattggccg
     4921 aaaattattg accaaaccac cagagccaac agtcaaaata aagtaaccga ccgttgcctt
     4981 taagaatcca gcgatgcatt catgaagcgg gcgtttcagc aaaatatagc ctaataacac
     5041 gataaaacca atcaggtatg ctggctgcgt caagatattt gttgcaaaat acgtccaaat
     5101 gcttaacaaa aattccccca tcttttttct cctctatcaa ttaattatat tctgccatca
     5161 caacttggta atcatcgatg gagttcgtag agatgagacg ctcaaccaat ccatctgtca
     5221 ttaataattc ggataatttt tggatatttt ctagatgttc ttctggatct tttgctgcga
     5281 gtgtaaaaaa caaactagcc gttttctcct cattctcccc ttcactttca aaacggattg
     5341 gctgtttcaa cttggtaaat gaaatagctg ttccaaaaac accatcactt ttttctgaag
     5401 aatgcggcat tgctacttga ggtgcgatca caatataagg accgtatttt tctacacaat
     5461 ggatgatctc ctccacatac gtttcatcaa taatttcctt atcgatcaat acaagacagc
     5521 tttcggcgat agcttcacgc caatccgtga tttctttatc tgggtaatga atcaattgat
     5581 ggtcaaaaaa gtatttcagc aagaaactcc ccttctttct tataaaaacg acggaaacgg
     5641 tgtatcattt tcaatcgaga agacatcttc aaatcctcga taaaaattaa actcaagatc
     5701 atctttgttt gtcggataga tgaatttccc gcctacttgc cagatataag gtttaaatcc
     5761 atacttcagg cgatcctttt tgaatttcca aatttcagtg atctcttttg gatcagccat
     5821 aaaattagac caaatatcgt agtggacagg aatcactact tttgcattca atgactccgc
     5881 catgcgcagc atatcaacag aagtaacttt gtctgttatc cctcgtgggt tttcaccata
     5941 ggcccctaaa cagacatcga ttttgtgttc attaccatgt ttggcaaata aattggagta
     6001 atgtgaatct cctgcatgat aaagattccc tcctgatgtt tcgaataaat agtttactgc
     6061 aatttgatcc atctcctgag gcatttttcc ttttaatacc tcttctggat cttcacaagt
     6121 gaccaacgct gtccgatcaa acgcttctaa agctactaca ttgatgtctt tgattttgac
     6181 tgcatcacct ggctttactg taatcgtttt ttcttcagga attccccatt tttgccacgt
     6241 gcgaaccact tcttttggcc caatgaatgt tgcttcagga caattttgat gaactgctgc
     6301 ggctgtatgg atatctagat gatcggaatg gatatgtgta acgattaaag cgtctacatt
     6361 ttttatcgca aaaggatcga ttacgaaagg ctgagtacgt aaattaggct gcatattttg
     6421 aacgccactc atacgcatca tctgatggcc ttttttcatc atgccattcc catgactacg
     6481 ttttcccgtc ccacaccata gatcacataa aatattcgtt ccttcatgac ttttcagcca
     6541 aattcccgta cagcccagcc accacatagc aaaagttcca ggatccacta cttctgtttc
     6601 gatttcttca ttcaagtatg tgccccactc aggaaatgtt tctactaacc acttttcttt
     6661 tgttacttca ttgacagttt tactcatttg cttgctcccc ccatatcgtt gttccaactt
     6721 acaagtaaat attaatgtgt atcagcatcc atgaaaaccc ttttatatga ccgtttgttt
     6781 tttatatgat tttctttcag taatcaatga ttgtttcagt ataataaaga cagatatgaa
     6841 tgtttaaatg aacaactagt caaataaatc catggatcaa gatgtccctc aggaggcaaa
     6901 agtcatgaaa aactcacttg tcaatattga aaaacgtcaa aaagaaattt tggaactgct
     6961 tcagcagact gaacaactat caactttcga attagctgaa tcccttgatg tatctattag
     7021 tacgatacga agagatttaa atttattaga agaaaaaaac gagatcatac gcaattacgg
     7081 ttattgttct tataattaca aaaaccagac tgattttgat caatctggtc ctgaaaggat
     7141 taaacaagcg attgccagag aagctagtaa atacattaac gattatgata cgctgtttat
     7201 caattctagc tcgactgcgt tgaaaacact ggattttctt caatctaacc atttgacagt
     7261 cattacaaac aacgtgaaaa tcaattactc tccgcacaaa gataattgta gttatatttt
     7321 aactggtgga gagatgcgct ttccaaaaga agcactagtg ggcgacatcg cattaaatac
     7381 gatttcttca gtcaatgcag acatttgtat cattggctgt agcggagtcg atgtagtaca
     7441 tggggtcaca acaaagatat taaatgaatc aacgatcaac gaaatgatgg tcaacaagac
     7501 aatcaaatgt aagattttag tcgctgatca tcgaaaaatc ggactgacat caaagttcaa
     7561 gattgctgat atttcagtct ttgattattt gatcactgat aaattttgtt ctgaaaaagt
     7621 attagaggag atcagaaata cggggataaa aaccattcaa gtagattcat tttaagaacc
     7681 aggacgtaaa tatgtaaata ggattatcaa aaaaatgaat aacaaattta tcgataaatg
     7741 aaaaacacgc tacgctcaaa ttgataaagg aatcccaaga tgtatccatc caatcgatac
     7801 catcataatc tattgcttct tttataaccg ttatatgttg cctaaatagg aatcaaacaa
     7861 tatcgaaaaa aggaggtatg acaaaagtca cacctccttt tttcgaataa acggtattca
     7921 aatcagaaca ctgatttcac aaccacttta tttcaggtcg ttttcaatca cctttaccgc
     7981 gtaatcattt ccgttgaaac gcgctatttt ttttgcgtcc atatatcttt ctaaataatc
     8041 atcttctcct aattgcttat ggcaagaagc aatttcataa agcaagtatt ccaatgcata
     8101 agtcgattta tgtttcttat tatactcaat acccttctca cataattgga ttgctttatc
     8161 ataatcctcg attttacggt aataggtggc gatatcataa tatacaatgc agaccatcag
     8221 attatcaaaa tcagtctcac tcaatatttt aagtgtacgc tccacataaa ctttcgcaaa
     8281 atctaattct ccttttgaca agtagatcat tgccacgttt gcagctgctt gtaagtgatg
     8341 gatatctgtt tcggtcgttt gttccaacac ttgattaaaa taaaataatg ctgcatctgg
     8401 ttttttcgca taaagatgat caagcagtcc ttgataaaat aaaatttgat ttaaaagatc
     8461 agaattactt actttttcct gatcgatcgt ttgtaaaatt ttataagatt cttggtattt
     8521 tgatacagaa ttcaatgatt gaatctcatt tatttttttc ctgattttgt cttcttctgt
     8581 ttctactaat atatcggaga tctcgacatt cagctttttg caaagcgcac ttaagatatt
     8641 gatgcctggc gacatattct tgttttcgat attgctgaca gttgcttgtt cacaaatgcc
     8701 ttctgctaat tgtacttgtg ttaacccctt tttctttcgg tattctttta gtaatgctcc
     8761 atctacttta atcaaaacaa tttccttccc tttaaaaaat tatttctcct ttatatcata
     8821 cacaaaaaaa agttctaaac aaccaaaaat gtttagaaca gaataaaaat tttaatttta
     8881 aaataatatt caaattaaac aactggcgta tctgctcctt gatttctttt tgtgttatct
     8941 gaataattat cgtttacagt tataacacat agtgaaaatt gtcatggcga gaaagtctaa
     9001 gaatattttt aaacataact atttctttct tacgtgtgta taatgacgac agcacaccta
     9061 tcaattaata taattatttt atttttttat gttctcatgt ttatttttaa tgacacaact
     9121 tctcgtattt atctggcaca acatataaat cgatcaaaaa attgttgcgt gtttttttga
     9181 aaattggagt ttcaacttga ttacaaaatt taaatttaga agttgtgaaa acagcgagag
     9241 acagtttaat attcaaaata tacataggct actcgaacgc tgtgtttttt agtatactag
     9301 taagaaacga agggatagac tcattccaat aaggaggatt tcatgaagac aattcttttt
     9361 gctcctgcag tattcaattt agctgagaca acacgaatga ttgaggttgc caaagctatg
     9421 aaagaccgtt attactgtgt attctttggc ttttctaaaa cttttgctcc tttgatcaca
     9481 gaaagtggct ttgagtatca tttactagcg ccgatcctta cgaaaaaaca agaagaacaa
     9541 atcataaaat ttgaccagtt gcgtacactt aaaaaccctt ttaccaaaga aatggttgcc
     9601 tctcgtatca ctagtgaaca gagtctgatt gctaagtttg agcctcgact gattgtgaca
     9661 ggttcgaatg tgacaatttt tttatcggcc cgcaataaaa agattccttt agtatatgtt
     9721 aaaccctatg ctttgagtga accttttttt caatcagagc atgcgctgat gccccacgag
     9781 ttacgtttct tcggcccttt aagcaatccc ctttggcact ggacaaaaaa gcgtatagta
     9841 aatacccgat ggatccccaa tgccttcaaa cacgctgcac aaaaagaaat gcttccttta
     9901 ccaaaaacaa gtttacaaat gatggatgct gatctaaatc tcatcacaac gcctaaacta
     9961 tttttggaag aagaacagct gccggaaaat tatcgaatcg ttggtccaat ttttgctaag
    10021 ctcagtactt ccttgcctga agaagtgcta acttttatac agcgaaagca acaagaaaga
    10081 aaacgtatta tctatttcgc aatgggtagt tcaggcaatc cgcgtatgtt acgcaaaatt
    10141 ttgttcttct tacaaaaaca accggatcta gcggttattg cacctattga ctatctgctt
    10201 gatgacattc aatctgactc agaagatctt ttaataacag aatatctgtc tagtcatctt
    10261 ttgcatgaat tcattgattt ttcttttatc cacggcgggg aagggaccgt ccaaactgcc
    10321 tgtgaatccg gcaaaccgtt tatcggtgtg gggatgcaat ttgagcaaag ctgtaatatt
    10381 gactattgtg taaaatacgg aaacgcaatc gccctcacaa aaccagtgac tgaaagaaaa
    10441 ctgcagattg ctctgcgcga agtttcttca cccaagattc gtcagcaggc acgcacgctg
    10501 caagccgttt ttccaataaa tggtccacaa caagcaattc aagaaatcga aaccttcctg
    10561 agcaaccacc caatatagtt tcaagtagaa aaagcttttt taatagagac tcatcagtaa
    10621 tttcgctatt cgagacccag acagtgaaaa tacaaaaaaa gtaaatagtg gattgaaaag
    10681 ttagagttac ttaaattacg gtgtctaaaa aacacaaaat catccttaaa ataaaagatc
    10741 tgacgctatc caaatgagca taggtagcgt ctgccattta ttcttagtca aattctttga
    10801 cacctttctc tggttggatc atctcaacgt ttcttcaaaa gaaagaccat aataattagg
    10861 caaatacatt ttcttaaaat gtgtcatata gatctagaag catcgctttg tagagatttg
    10921 tgccgctagt cccctcaaca attactaaat caaatgtagg atttaccact ttatctttga
    10981 taatcaacct ccctcttctg ttgagacaat gatctcgcaa tccgatgcat actcctatat
    11041 aaactgccag caatccccac atattgagta gatcatgtca gaatgttcta tgtcgtcagc
    11101 aacgatacac taaaagtcac gttcaccatg actgattgct attcccagca caattatttc
    11161 tatacacgtt tcatgatttg aataaacact cacatcatac atattaccat tcatacacca
    11221 tactgcagcc cctactatat ggttgtaagc tcccaaatct atatttgact tgatcacttt
    11281 ggtagtagat ctactaattc taaatccatt gctgataaaa tttccatttt ttcctccttc
    11341 tttctgccaa aacagttaaa acaataataa tctttatgta aaaaagggct gtgacaaaag
    11401 ccttgtcaca gtcccatatt ccgaataaac ggtggtcaaa agcttgcatc tgcggtaata
    11461 agttcaacca aacgaaaaat aagccaacat ttcacaaaaa tttaagaagc aattttcgta
    11521 aatttcttct tatttcttga agctaaccac ttctgttaca accactttta gaacatttaa
    11581 agcttcgatg tgacaaacca tctatgctgc tcgatcataa aattgatagc aaaaattcca
    11641 caaagtacat atgtccccca tgaaaacaaa acattcatat gcggtacaat gatctttgga
    11701 agaatcacga tcaaaaatga tgccagtgcc caaatccatc gattgatttg aatatgatat
    11761 gtagctagca tattcaatat aaggtgacta gccgttaata aaaagataaa aacaaaaaat
    11821 aaaatcagcc aatacattgt ttcccacctt ctaaaaacca aacttagaca gtctggactt
    11881 cgttttctcc acgactttgt tcatctgaca gcatcttttt atcataagct tttacaaatg
    11941 gataatagat aataaatgct atcaatgtgt tgatcatgat caagataaca acacgccagt
    12001 catttcctgc tgaaagataa ccgccgattg gagctggtaa tgtccatgtt ggcaaaacag
    12061 taaatctatt gaccatttct aatttgactg caaaataact gataatagtc aaaactaaag
    12121 gaactaagtt gaacgggatg aacatgtaag gattcaacat cataggagct ccaaaaatta
    12181 tgggctcatt gatattgaag ataccaggaa taatagaaaa acgaccaacc tctttcaaga
    12241 attttgattt acagaagaat ataaacaaaa cagataccac gatcgttgct cctgcaccac
    12301 caattgttac cgtccattga taaaactgtt caggagcgat atagggtaat tgggtggcag
    12361 ctgtaccatc tgccaatgcc tttgcattct catccaacat gatcagccac attggacgaa
    12421 caacagcccc tacaatactc atgccatgga taccaaatga ccacaacaaa tggatcaaaa
    12481 acattggtag taaaacacca agcaaattat tccctaaaat attggttaaa ggctcgaata
    12541 acgataataa ggcagcgttt acatcaaagc ccgcgacgct tcgaatcagc caagtaattg
    12601 ttaaaatgac tgcacctgga atcaatgcct caaaactacg ggcaacagca ggtggcactt
    12661 gttctggcat tttgatagta atatttcgat ttttaaagaa acgatatact tccactgcaa
    12721 aaatcataga taagatcccc gcaaacatcc cagatgctcc caaagaactc ataggtaaga
    12781 cccagccaag aggtgcctct tcaggagtta aaacgtttac aggaacttgt aacataaaga
    12841 acgttcctaa agataatata ccacctgtca cactatctaa tccatatgat ttagctagat
    12901 ccgaacccat aacaaaagtt gcataaatag ccatcaatcc catcgtcatc ctaaagggta
    12961 aaacaatcgt tgccgaataa ggggcaataa attcattcca tccaggaaac ggtaaattga
    13021 taaagaccat aaaaaatgtc ccaatcaaaa tcaatgacaa tgttgaaaca accccattac
    13081 gaattgctaa taaatgacgc tgtgtaccaa tttttgccat tggtgggaca agtttctctt
    13141 cgacccattt catcagcttt tccactaaaa ccactccttt tcaataaaat atgaaccatt
    13201 cattgcatga caacgcaaag aatgttcata actaattata taattaagaa attttatttc
    13261 aatatattct cttaaataat caaatttatt tttaagaatc ctgaaaataa gttttctaaa
    13321 tcataggagc aacaaaaaaa ttcgataatt aacaaaaatc aaaatgatta aatctagtga
    13381 ttgaaacata tcatttcaaa aaaattttgt aaattcaccc ataaatatca ccctatttaa
    13441 cttttttcat cgtacactaa aattcaaaac aactatcttt aatctttact tcttggtttt
    13501 gttttaataa atttccttca aaaatgcctg gagaaactac aatgatcacc gtatcttttt
    13561 gtgcttgctc caacttcttc aaatctataa tagctaacag tgtcccttct tttacctcct
    13621 ggttactttc aacccgtatc tgaaacggac ttccttcgag ttcaactgta tctaaaccca
    13681 tatggatcag tatttttctg ccagattcac tttcgatcgt tatggcatgt cgggtaggaa
    13741 atatattatc gattattcct ttaactggcg catggatata tccatcatga ttcgttatag
    13801 cgtatccaac tcctatcatt tttgaagaaa agacctcgtc ttttactgct gttaatggaa
    13861 taatttgacc actagctaca gcttttagaa tgtttcttgt tttaaagaaa tgcacttttt
    13921 atcacctcta ctttaatgct ggccaatatt ttttgtttac tttgatcatt tcatctagta
    13981 ttttttttgc gactctggca tttggtacgg tttgattcaa tgtaaatgct tgtaaagctt
    14041 tttgataaga accttcaaag taagcatcta ctagtaactt ctctactgca acttgtgcct
    14101 ccatcaatcc tttatgaaaa tcactgattg gttttcttag tgtaattggc tccacaccag
    14161 ttgcaccaac atatgccggt atttcaacaa ctgcatctga ccgtagattc ggaatcgccc
    14221 cttgattagg aacgattagc ataaagcgac gacgatcatc attcaacaag gaaatagcta
    14281 tatcgacgat atattgtcca tgctccccaa aattaaagtt caatacttct tccacaatac
    14341 cgcggcgtat tttatcagcc atttctttgg tatttttctc tcgtccatcc atgaccatat
    14401 tagcacgtgt atactctttg tcagtatgct caacgaccat atcaggatat aagtaatact
    14461 ctaagtaatt attcgggata ttacttggaa aatttttcgt gatgactgac atcatttgaa
    14521 aggttttttg ccaagtttta tctcctatat taaaatcggc gacttgcatt tcttttgtta
    14581 ttagtttttc aataatctct ggcataattt ctcgttgcaa ttctttatca taaatcgatg
    14641 tataccagcc aaagtggttt aaaccataat acgtaacgat ccaattctta cgatcataac
    14701 cgtaattcac tgcaatcgtt tcttcaattg aaatagtcat atcacaggca ttaatcattt
    14761 ttacattcgg atatttacga cgaacagctt cagaaacgat cgactctgga tttgtataat
    14821 tcaaaatcca tgctttgggg gcatagtctt gtatatgatc gacaatttcc aataaacctt
    14881 tgattgagcg catcccataa gcaaatcctc cgagtccaca cgtttcttgt cctactaatc
    14941 catgtttaag tggaatcttt tcgtcctttt ctcgcatctc caatcctcca acacgaattt
    15001 gtgagaaaac aaaatcgcat cctgtaaaag caagctttgg atcatccgtt gcacgaatgc
    15061 gaatatttga aaaacctttt cttttcagca taaatttaac aatcaagtac atatccatat
    15121 ttctttcttc atcaatatca tataaacgta tttcagataa tggcaaccgt ttttcattgt
    15181 tcaaaatggc ttgaacgatt cctggtgtat acgtactccc gcctccagct atagtgataa
    15241 tctgtttttt catcatcatc ttttcctttc tattcttcta ataatttatt gaattctgcc
    15301 ataacataag tcacttctaa gccgatgata atttgataat ttttttcagt tggtttaatg
    15361 atcccgctta tccctaattg cttgattcgc tgttcctcga ccatggtggg atccactacc
    15421 tctacccgta ggcgtgtatt acaactatag acatccagga tattggcttt tcctccaaac
    15481 gcttgtagca tttttgttgc catatattca taatttttac ttgctaaccc taactctgtt
    15541 tcttctaagg ttacttcatt gccaaactct gccttagctt cacgtcctaa tgtctgaatg
    15601 tttctcttat tgatcaaata ataaaaagta acgtaataca aggcaaaaaa gaaaattccg
    15661 attggaagaa tcaaaatagc attggtagcg attcgaaaat tgatgagata atcaacaata
    15721 catgctccga atgtaaaacc aattcgtata ttgaataagt aacagacaat ccctgctaaa
    15781 ccggcaaaaa gtgcatggat cacgtacaac ataggagaaa gaaacatgaa actaaattca
    15841 acaggctcag tgatatttgc aataaatgaa gttcctgcac cgcttcccat gattcctttg
    15901 accatctctt tattttcttt ataagctgct ttatagatag ctagacatat agctggtata
    15961 ccaaacatca ttactacaaa aaaaactgat aaaaacagtc cagcctgagg atctccgttg
    16021 ataaagcgtg tcatctctcc tctgaaaact tccttgctag gagatgtata gcttcctaaa
    16081 tcgtaataaa tatacgtatt caacacatgg tgcagtccaa aggggatcag caaacgattc
    16141 aaaaacataa atatccccac acctaatgct cccatatcaa cgagcagttt tgcaaaatta
    16201 tcaatcccaa tttggatgag cggccagata aagcccaaaa aaacagctgc gattgtttgt
    16261 agaatcatca ccatagtcaa tgggaatttt tcgcccgcaa aataagaaaa aactactggt
    16321 aatttttgtt ctttaaagcg attatacgtc catgccgcta ctaaaccgga aataattcca
    16381 ccaaaaatcc ccatattcac ttctgggtcc ataatttcta agcctttttt caaggtagca
    16441 atcgctaaaa aaccagtaag tgcaggtatt cctttgtcct tatttttgac aaaaccgatt
    16501 gcaactccta tagcaaataa gatatccaag tttccaaaaa cggcatttcc agctgcacca
    16561 attactggga tgttcagcat atcgtcagct gataaacgca tgatcaatcc cgctaatggc
    16621 atcgctgcaa ctggaagtag catcgctctt ccaagcttct gcacatttga tttaacattc
    16681 atttttattc ctcctctatt aaatatcctc atatgttact aactcaatca aaggatcatt
    16741 tttcactttt tgagcaaatg ctgaatgaat taaaaattcg acttggtggg tacgaggata
    16801 cacaaaactt gaaccattta acaattcctg atccaaatac gctgcgtgac acatgacttc
    16861 gatcgtttta tcttctctca atatcatgag taaacttgcc aaatattctt ccacactcgt
    16921 attgatttgt cgtttttttt catcagtttc tcctacgaca tcgaaacaag gctcaaaata
    16981 atcgacatga cgaacttcat cttttcgttc aaagttgctc cgaaccggca aatcatattt
    17041 ttttgctaat gtaacaacta cctcctgatt ttcatccaaa gtatgagtat gatgatgact
    17101 gtctaaatga gttggtatga tccccgcatg ataaattttt tgaatctgag cattccattc
    17161 ctgatacagt tgatctttgt caatgttaaa tggatgctga taataagata aggatctgaa
    17221 ctctccgctt tcgataagag tatcgacagt tttgaggagt ggtttgccac acgtcaatgt
    17281 taaatggact cctacaccta gcctaggcat ttcctttctt agtttcacag catgctcgaa
    17341 acccggcata tttgccatca atgtagttga tgtcaaaatt cctcgctgat aagcatccat
    17401 aatcccataa ttcacaccat ggctatagcc aaaatcatcc gaattaaaaa tcacttttcc
    17461 catttcattc tccttctttt ttctactaaa ataggcgcaa ccaaataatc atagtccatt
    17521 tactatgtgt catttggttg cgcctataga tagttacgcc cttattttaa tagattcttg
    17581 ctagatgaat tgccaaatag atgatttcat tttcttgaat ggcaagttga aattgctgtt
    17641 cgatgatatc tttaatcttt agtgctgtac aatacgcttt gctatgttta aatgtttcag
    17701 taaaaaaacc aatattttct actggcgttt cttcctgata aatcaagcgt ttaaccagga
    17761 atttgatatg aaccattaag cgatgataag tcagtgattc tttatcataa acgtttgaat
    17821 aggatttttc tagatgggac aaaatcgtgg tcgtcatttc tactattttt aagctcttta
    17881 aactattagg ctctcctagc tcagcattaa tgatatgcat agtgatgaat cctacttcat
    17941 ttgaccctaa ctcggtttga tatcgatgat tgattcgctc gaccacttct actgctatat
    18001 catattcatt tggataaagg aatctcattt ctggcaacat aattgctgtg acatctctat
    18061 cttctctttt tcgttgaata gcaaaataaa tatgatctgt caatgtaata tagatatttg
    18121 aatctaatgg agaggagatc ctagctgtta tcagttcaat cacttcttcc gcaaaatcca
    18181 taaattcgat tggaatctgc gagactatct cactgaatcg tttgatcttt tctttagaat
    18241 ctaatacaaa taatttgtca gcatcctcaa catcaaatgg cttactcact ttagcagaaa
    18301 agccaatccc tttccccatc gcaatttttt ctattccatc gtcatcgatc aatacagcat
    18361 tatgattcag ctttttcatc acatacaccg ttaattcacc tcctctatat gataaaacaa
    18421 aacaacttgc agactccttc atacatattt ttgtctccaa acaattttta aagacaaaaa
    18481 acgacctaag aaagaaccct ttcttaggtc gtgcctaatt gaatagtagc accctacata
    18541 atttacaaaa atagtttaac acataataaa agcgttatca atatcttttt tactcgtttt
    18601 atgataatac ttgtatcgaa ttgatttgga ggtaattaca taaaaacaaa aaaaatatag
    18661 caactctcta taagaaagtt gctatattga taattatacc ggcggccggg gtcgaaccgg
    18721 cacgtcctca acggacactg gattttgagt ccagcgcgtc tgccaattcc gccacgccgg
    18781 caaatttaaa aataataact ggggtagctg gattcgaacc aacgcatgag ggagtcaaag
    18841 tcccttgcct taccgcttgg ctatacccca agaataaagg gcgaatgatg ggaatcgaac
    18901 ccacgaatgc cggagccaca atccggtgcg ttaaccactt cgccacattc gccatcataa
    18961 aagatgttat ttaatttctc aataaaaaac taagatgaag acatcttagt caataccggc
    19021 ggccggggtc gaaccggcac gccctcaacg ggcactggat tttgagtcca gcgcgtctgc
    19081 caattccgcc acgccggcaa gttgatttat tagtactaag gcggtaaccg gatttgaacc
    19141 ggtgatgaag gttttgcaga cctctgcctt accacttggc tataccgcca ttatactatt
    19201 atcaatctat aaaataaaga ataaattata gaaactgggg tagctggatt cgaaccaacg
    19261 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaaaagggc
    19321 gaatgatggg aatcgaaccc acgaatgccg gagccacaat ccggtgcgtt aaccacttcg
    19381 ccacattcgc catggcaggg gcagcaggaa ttgaacccac actaacggtt ttggagaccg
    19441 ctgttctacc tttaaactat gcccctataa aatggaggag agtggattcg aaccactgaa
    19501 ccctaaggaa cggatttaca gtccgtcgcg tttagccact tcgctactcc tccatggtgg
    19561 cgcgggacag aatcgaactg ccgacacacg gagcttcaat ccgttgctct accaactgag
    19621 ctaccgcgcc atattttaaa attattaatt gaataacaag aacgacggtt ccgacgggaa
    19681 tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa cccctacacc acggaaccag
    19741 ttcattatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
    19801 cccagctgag ctaaacctcc aacattcaat taaaatgacc cgtacgggat tcgaacccgt
    19861 gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca acgggccagg taaatttgct
    19921 acggagagta agggattcga acccttgaga cagtttggca ccatctacat gatttccaat
    19981 catgctcctt cggcctctcg gacaactctc cagagtgaaa gaagctcaat actctttctc
    20041 aaaatgagaa ctccggcagt aggactcgaa cctacgacat catgattaac agtcatgcgc
    20101 tactaccaac tgagctatgc cggaataaca tcagcgtggc gacgtcctac tctcacaagg
    20161 ggcaacccct cactacaatc ggcgctaaga agcttaactt ctgtgttcgg catggttaca
    20221 ggtgtatcct tctcgctatc gccaccacac tgtggtgtta tcttttattg agtaaatttt
    20281 gttcactcaa aactggattt gaagtcacat aagttttttt ccgagt
//
LOCUS       DADVXV010000054        19950 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.055, whole genome shotgun sequence.
ACCESSION   DADVXV010000054 DADVXV010000000
VERSION     DADVXV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.055"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            299..1960
                     /locus_tag="KB969_001826"
     CDS             299..1960
                     /locus_tag="KB969_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6869795.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2392)
                     /locus_tag="KB969_001827"
     CDS             complement(2030..2392)
                     /locus_tag="KB969_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBB6869796.1"
                     /translation="MKEQSNEKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFL
                     WSLPFLIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLII
                     AGILIALSAIFMLFSLLG"
     gene            2460..3401
                     /locus_tag="KB969_001828"
     CDS             2460..3401
                     /locus_tag="KB969_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869797.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3402..4445
                     /locus_tag="KB969_001829"
     CDS             3402..4445
                     /locus_tag="KB969_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869798.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4451..5521
                     /locus_tag="KB969_001830"
     CDS             4451..5521
                     /locus_tag="KB969_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869799.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5511..6464
                     /locus_tag="KB969_001831"
     CDS             5511..6464
                     /locus_tag="KB969_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6869800.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6476..7486
                     /locus_tag="KB969_001832"
     CDS             6476..7486
                     /locus_tag="KB969_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6869801.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7771..8592)
                     /locus_tag="KB969_001833"
     CDS             complement(7771..8592)
                     /locus_tag="KB969_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBB6869802.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8689..8967)
                     /locus_tag="KB969_001834"
     CDS             complement(8689..8967)
                     /locus_tag="KB969_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869803.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9235..11244
                     /gene="metG"
                     /locus_tag="KB969_001835"
     CDS             9235..11244
                     /gene="metG"
                     /locus_tag="KB969_001835"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBB6869804.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11723..12310)
                     /locus_tag="KB969_001836"
     CDS             complement(11723..12310)
                     /locus_tag="KB969_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869805.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12485..13807
                     /locus_tag="KB969_001837"
     CDS             12485..13807
                     /locus_tag="KB969_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6869806.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13962..14738
                     /locus_tag="KB969_001838"
     CDS             13962..14738
                     /locus_tag="KB969_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6869807.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14731..15300
                     /gene="rnmV"
                     /locus_tag="KB969_001839"
     CDS             14731..15300
                     /gene="rnmV"
                     /locus_tag="KB969_001839"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBB6869808.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15293..16177
                     /gene="rsmA"
                     /locus_tag="KB969_001840"
     CDS             15293..16177
                     /gene="rsmA"
                     /locus_tag="KB969_001840"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBB6869809.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16628..17257
                     /locus_tag="KB969_001841"
     CDS             16628..17257
                     /locus_tag="KB969_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869810.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="KB969_001842"
     CDS             complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="KB969_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBB6869811.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18699..19121
                     /gene="mgsA"
                     /locus_tag="KB969_001843"
     CDS             18699..19121
                     /gene="mgsA"
                     /locus_tag="KB969_001843"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBB6869812.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19444..>19950
                     /locus_tag="KB969_001844"
     CDS             19444..>19950
                     /locus_tag="KB969_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBB6869813.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKI"
BASE COUNT         6491 a         3584 c         4072 g         5803 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt tttcatttga ttgctccttt atttttggtt
     2401 cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg gaaacattag
     2461 tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc acgctttggt
     2521 taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca tatacgaatc
     2581 aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt ttggataaac
     2641 cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat tttggaattt
     2701 ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc ggaccatcct
     2761 tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt ttaggaacga
     2821 tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta gcgatattag
     2881 gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt gcaatcaaat
     2941 tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta ccaacaattg
     3001 cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa atggtggaag
     3061 tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt tgggaaatcg
     3121 cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta ggaccgttag
     3181 ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt cctggtatcg
     3241 gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg gctgtaacga
     3301 tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg tacggtctag
     3361 ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg ataccaaagc
     3421 gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa aaaaataccg
     3481 aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat tcatggcgcc
     3541 gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc atcattttga
     3601 tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac gtggcttata
     3661 tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga aaagcaatgg
     3721 ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac gtaaatttct
     3781 ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg ggaatgagaa
     3841 tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt gtagcttacg
     3901 ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa
     3961 tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt tttgaaccag
     4021 gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg gcacgtatcg
     4081 ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga ttgacattag
     4141 gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct agtgtcatta
     4201 ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt ttaagcttta
     4261 tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc gaagggtaca
     4321 agacattcct gtatctgcct tatctattat ggattccggc agtaacttta tcggttatca
     4381 tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag
     4441 agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt ttgatacgta
     4501 tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag gagaaacatt
     4561 ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca tcatgcgctt
     4621 gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta acgatatcgt
     4681 tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca
     4741 agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg ctgagtccct
     4801 tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag aattgcttaa
     4861 attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc agttctcagg
     4921 aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg aaatcctgat
     4981 tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt tggagctgct
     5041 gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg accttggtgt
     5101 agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg
     5161 aacatcggaa gaaattttct acaacccgca acatccctat acttggggac tgcttggttc
     5221 aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt ctccaccgga
     5281 tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg cgatgaaaat
     5341 cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg cagcaacttg
     5401 gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac gtcgctgggc
     5461 tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg atgccaaata
     5521 aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac
     5581 atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt ttagttggag
     5641 aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat gaacctactg
     5701 atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa aaaggtttga
     5761 cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg ttgaatcctc
     5821 gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta gctaaatcat
     5881 ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg aatccaagcc
     5941 acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt ggtattgcac
     6001 gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct gcactagatg
     6061 tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa catcaattga
     6121 cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac cgaatcggtg
     6181 taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat aatcacggtg
     6241 ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca gaccatgaga
     6301 gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta cgtcaacttc
     6361 gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca tattacgcaa
     6421 aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga catagatgct
     6481 aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat tgattcgtac
     6541 ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga aaagttggca
     6601 acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag aatacccatt
     6661 cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg atcgggcttt
     6721 tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg
     6781 gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg gctacttaaa
     6841 gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg aaggatcgat
     6901 tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac tactttgtga
     6961 tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct atcatccgaa
     7021 gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc accagacaga
     7081 agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag
     7141 aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag taatggatct
     7201 ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg ggaaattggt
     7261 caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac atgctgattt
     7321 ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc aatggtataa
     7381 taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg taagaaagag
     7441 ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa tgaatgaaac
     7501 tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt tgtttctagg
     7561 aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca atagcagaaa
     7621 aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt tacgaataca
     7681 tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt ttttcttgaa
     7741 tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct tgagctgata
     7801 gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga aatattggag
     7861 catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta agaatttagc
     7921 aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta gaacttgcgg
     7981 ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt gactatggtc
     8041 aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg agatagccac
     8101 ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc agcgtacttc
     8161 cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt agctgactgt
     8221 gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt gctcaatatt
     8281 ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc tttctccagt
     8341 tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat aaggatgccc
     8401 ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc acatcagtac
     8461 gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt gataccagtt
     8521 aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt ctttagaagc
     8581 aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct tattgtagca
     8641 gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt aaatatgaaa
     8701 aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca atactttata
     8761 ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa tgataaaacg
     8821 caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa aataaccata
     8881 catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag caatactaag
     8941 tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag atagatagtc
     9001 tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga tatgaaacaa
     9061 aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt gaacgtagat
     9121 agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg ctttttttat
     9181 ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag ccccgtggca
     9241 gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa acttcatatc
     9301 ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg gttgatgggc
     9361 tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga aacaaaagca
     9421 gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga tgtcaagaaa
     9481 ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga tgattaccat
     9541 aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat ttacttaggt
     9601 gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac acaacttgca
     9661 gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag tggacacgaa
     9721 gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc agaccgtcta
     9781 ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa aaacgaaatg
     9841 atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac aacttttact
     9901 tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat cgatgcatta
     9961 tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt cgaaaaatac
    10021 tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac gatctattgg
    10081 ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg gcatggctgg
    10141 ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg
    10201 cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc tgttccgttt
    10261 gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta tgatctggca
    10321 aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata ttgtgatgga
    10381 ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc tacgacggct
    10441 gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa tacagcattg
    10501 gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac agaaccatgg
    10561 gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat ccatttagct
    10621 gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac gccagagaag
    10681 atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt acactttggc
    10741 gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc acgtttagat
    10801 atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca aacaaacgaa
    10861 gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga aaaacaaatc
    10921 aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa
    10981 gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag ccaagaccgt
    11041 caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat cgggaaaaaa
    11101 gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg
    11161 atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc aaaatccatg
    11221 ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt tgtgtcatac
    11281 cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta cttgaagcca
    11341 atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag aagtacgagc
    11401 ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac agaaaaaaag
    11461 cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt ttttattgtc
    11521 cttacattca taaagtttga atgcaatgac tttattacat ctatatttat atctaacagt
    11581 agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt gtgctcttat
    11641 atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg atgattgttt
    11701 tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt tttgtcttca
    11761 aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca taccagaaaa
    11821 tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt aacaagatca
    11881 accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg acttcactaa
    11941 gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc atccgccagt
    12001 tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag
    12061 gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc acaggacctt
    12121 tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt gataacgttg
    12181 caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt
    12241 ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga taagaacgct
    12301 taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa
    12361 aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa aaagaatggt
    12421 aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa gaaagaggat
    12481 gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag ctaccgttat
    12541 gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg ctagtactca
    12601 gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga tctgtgctgg
    12661 attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg taaaatatat
    12721 tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa gcttgattta
    12781 ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga cgaacttatt
    12841 acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt ctgtgacagg
    12901 gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa
    12961 attaatacca attgctgtga ttgtcatatg gggattattg accccaggac aaggaactgt
    13021 ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc
    13081 gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa tggcagggga
    13141 aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga gttttgtaac
    13201 agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg atcatcttgc
    13261 cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa
    13321 gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt atacactaac
    13381 tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca gtaaacagct
    13441 gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc agttagcagt
    13501 agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt tgatttttgt
    13561 gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa aaaaagcgcc
    13621 ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta ttgcgattct
    13681 cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag cattgatcgg
    13741 tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga
    13801 agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct agatcttcgt
    13861 gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact tctgcaagta
    13921 gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt gattctcata
    13981 cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag cgagcacaag
    14041 aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt
    14101 tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat ccgacagagg
    14161 ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact ttaccaaagg
    14221 ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg aaagaagtcc
    14281 aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta ccaatcagta
    14341 ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa gatgttcgag
    14401 atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa cgatttcttg
    14461 acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc
    14521 aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat gccccttatc
    14581 tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt tatacagtag
    14641 aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa acatggacaa
    14701 atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca agagattata
    14761 gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc agatacgata
    14821 gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca tgcccaagag
    14881 actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat aagaaaaatc
    14941 attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca agctaaacca
    15001 aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt agaagcattg
    15061 aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac tagacaagac
    15121 cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga aaaactaggt
    15181 gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt gaagatgttt
    15241 cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca acatgagtga
    15301 atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac atggtttttc
    15361 atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa ggaaaatcgt
    15421 agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc
    15481 attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg
    15541 tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta ttgtacatca
    15601 agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg aggagcttcc
    15661 gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga tgcattttct
    15721 tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag tagctgatcg
    15781 tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg ttcaatatta
    15841 tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc agccaaatgt
    15901 agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag tgacagacga
    15961 aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa cgctttggaa
    16021 taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag caaaaagctt
    16081 ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac aagaattcgc
    16141 cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt
    16201 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatgt
    16261 ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    16321 ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa acagcttctc
    16381 atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact attatgccga
    16441 acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat
    16501 tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat gtgtcttgac
    16561 agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat attaggagag
    16621 agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat tgattgggat
    16681 gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt cctttacttt
    16741 ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg cagtggctgt
    16801 tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg cattgcgagc
    16861 attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc atccgagtat
    16921 cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt tcaattttgt
    16981 gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt actttattgg
    17041 taatatgcct gaaacatatt attctcaagg atatttttat acagtattca tcttgatggg
    17101 gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta tagcaggaac
    17161 actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa atcggaaaga
    17221 gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca aaaaaaaaac
    17281 tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc taaaaagagc
    17341 tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt ttgatgactt
    17401 gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg tcgactattt
    17461 cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta gaaccagttt
    17521 ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct gatttcacta
    17581 cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct ggacgaatac
    17641 cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt tttccttcag
    17701 gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat gtcacattaa
    17761 agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg ggtgtatcat
    17821 aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata acgattcggt
    17881 cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt gtttcaagac
    17941 gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca tctaaatttg
    18001 ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt cccaatgcca
    18061 cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat tctgtcagac
    18121 ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca tatttacgta
    18181 atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt
    18241 ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact tttccgccga
    18301 tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa gtagttgact
    18361 ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt gatagattaa
    18421 aatcagttac agaataattt tctgcattgt catatttttt atatacgttt ttcagagcca
    18481 tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt taaagtataa
    18541 atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt ttttttgtca
    18601 atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat acactggagt
    18661 aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc
    18721 atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca atattggaaa
    18781 aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca accggcttgc
    18841 cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga gccatgattt
    18901 cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca cagccccatg
    18961 aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg ttagctacga
    19021 atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta gattttcgaa
    19081 gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc gtatggaaaa
    19141 ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga taatatgcga
    19201 tataatacga acgtattgga taatataaac aataatatta gtttttcgta tttgcagtaa
    19261 atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac agagtagaaa
    19321 ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga cgtaatgttc
    19381 gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa ggagatgcta
    19441 aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt attgattgca
    19501 ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa aatcagtgtc
    19561 acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc agggataggc
    19621 gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt ctttattgga
    19681 tttacattga atgcatttat tgaaggagca atctacggat tctttttcta tcgaaaagag
    19741 atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat caacttattt
    19801 ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg ggtcgtttgg
    19861 gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc catttattac
    19921 gtaggacgta gtattcctta caaaaaaatt
//
LOCUS       DADVXV010000055        19635 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.056, whole genome shotgun sequence.
ACCESSION   DADVXV010000055 DADVXV010000000
VERSION     DADVXV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.056"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="KB969_001845"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="KB969_001845"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBB6869814.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="KB969_001846"
     CDS             complement(1174..1869)
                     /locus_tag="KB969_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBB6869815.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="KB969_001847"
     CDS             complement(1882..2598)
                     /locus_tag="KB969_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBB6869816.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3536
                     /locus_tag="KB969_001848"
     CDS             2928..3536
                     /locus_tag="KB969_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBB6869817.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            3861..4184
                     /locus_tag="KB969_001849"
     CDS             3861..4184
                     /locus_tag="KB969_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBB6869818.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4366..5736
                     /locus_tag="KB969_001850"
     CDS             4366..5736
                     /locus_tag="KB969_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBB6869819.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5866..7167)
                     /locus_tag="KB969_001851"
     CDS             complement(5866..7167)
                     /locus_tag="KB969_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBB6869820.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(7521..9479)
                     /locus_tag="KB969_001852"
     CDS             complement(7521..9479)
                     /locus_tag="KB969_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBB6869821.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9656..9922)
                     /locus_tag="KB969_001853"
     CDS             complement(9656..9922)
                     /locus_tag="KB969_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6869822.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10432..12558)
                     /gene="pnp"
                     /locus_tag="KB969_001854"
     CDS             complement(10432..12558)
                     /gene="pnp"
                     /locus_tag="KB969_001854"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBB6869823.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12746..13015)
                     /gene="rpsO"
                     /locus_tag="KB969_001855"
     CDS             complement(12746..13015)
                     /gene="rpsO"
                     /locus_tag="KB969_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBB6869824.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13266..13829
                     /locus_tag="KB969_001856"
     CDS             13266..13829
                     /locus_tag="KB969_001856"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBB6869825.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(14082..14603)
                     /locus_tag="KB969_001857"
     CDS             complement(14082..14603)
                     /locus_tag="KB969_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBB6869826.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14606..15448)
                     /locus_tag="KB969_001858"
     CDS             complement(14606..15448)
                     /locus_tag="KB969_001858"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBB6869827.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15441..16166)
                     /locus_tag="KB969_001859"
     CDS             complement(15441..16166)
                     /locus_tag="KB969_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBB6869828.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16342..16638
                     /locus_tag="KB969_001860"
     CDS             16342..16638
                     /locus_tag="KB969_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869829.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17206..18798
                     /locus_tag="KB969_001861"
     CDS             17206..18798
                     /locus_tag="KB969_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBB6869830.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18811..19551
                     /locus_tag="KB969_001862"
     CDS             18811..19551
                     /locus_tag="KB969_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6869831.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5620 a         4028 c         3725 g         6262 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcaaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aagaaagcac aggtgaaggt ggcgaaccag aagtgatcgg ttcaacagaa gaataatact
     3541 gaaacaatca ggtggtgtta gaagcggcgg gtcagcagct tttaacacgc cttttttatt
     3601 tctaatcgtt tattttcata tggggcttcc acttttgtaa atggctttac aaacgaaaaa
     3661 tcctaattta ccaagctttt cctcgcatac ttttatcgta cctttataaa aatttatact
     3721 ttgaaaaaaa gtattcaatt attgttgcat ttttcctgat tctttattag aatgaaccct
     3781 cgttgaagta agtatttcta gtttatccta ggattaatta taaaaataaa acattcgttg
     3841 attcgaagga ggttaaacag atgtttgaaa gttttgatag cagccgcaac cgttacgctt
     3901 cagttggtgt cgtatcaagt ttgccagatg aattgattga cagtatatgg tttattattg
     3961 acctagatct taagggagtc attccattag aaaatatatt aacctttgat ttgatcgaaa
     4021 atcgtggaaa agtgacgatg catttttctc aagcaggaag caatgtggaa atggatattg
     4081 atttgccgtt tgcctattcg aaccaatttc ctgctcaagt atacgcctat gatgacggta
     4141 cgagagaaac gatcctttta ccaagtgaga ttagacaata ttaaggtgat agataaacgt
     4201 ggatgtccct tattttacag accaggccaa gttgttgatt ctttgactca attcttggct
     4261 tctttttatg gagtttcata aattatcatt gatttctaat tggtattctc aggataaacg
     4321 ctatatacta ctaactaaat tttaaagata taaggagttt aaaagatgcg cgatttaaca
     4381 aaaggaagcc ccgctaaact gattttgatg ttcactgttc ctttactgat cggaaatgtt
     4441 tttcagcagt tctacaatat gatcgatatg atcatcgtgg gtcagacgct aggtaaaaat
     4501 gcgctggcag cggttggtgc aactggaagc ctgacatttt tgatcattgg ctttgcccaa
     4561 ggtttaacag ctggtttagc cattattacc gcacaacgtt acggtgcaaa agattatcgg
     4621 ggtctgaaga aaagttttgc tgctagtgtt gtcattagtc ttgtcgtcac tgtgatttta
     4681 actgtcctaa gtctcctgtt tattcgtccg atgcttcaat tgatgcaaac tcctcctgaa
     4741 atacttgatc aagcacaaac atttatttca attattttat tagggatctt tgcatcagtc
     4801 agtttcaatt tgctttctaa tgtcattcgc gcacttggtg acagccgcac accactattc
     4861 tttctgatca ttgcggtcat catcaacgtc gtacttgatt tgatctttat tatctatttt
     4921 ggcatgggtg tggaaggtgc agctattgct acagtaatcg cacaagtttc ttccagcgta
     4981 ctgtgtctag tgtatatcaa gaaaaaaatg cctttgttac agttacgcaa aaaagatttc
     5041 aaatttgaaa aagaagagtt tgctgtacac ctaaatgctg ctttgccaat ggcgtttcaa
     5101 tcttcgatca tcgctgttgg tgctatcgtg ttacaagcag cactaaatag tctagggaca
     5161 gatgtcgtag ctgctcaagc cgctgctggt cgtatcgacc aatttgcaaa tcagccgatg
     5221 atgtcatttg gtattgcaat ggcaactttc actgcacaaa actatggtgc gaaagaatat
     5281 ggccgaatct tgcaaggggt acgtcaaact ttactgatga gtgtcggatt tagtctctta
     5341 gcaggtgcta tcgtcatttt cttcggtcat ttctttgttc aattgtttgt tagcccatca
     5401 gaaacacgtg tatttgaatt agcacaaacc tacttcaata tcaatgggtc tctttactgg
     5461 atcttagcag tcctgttcat tttacgctac acacttcaag ggcttggaca aagcaagatc
     5521 cctacgatcg ccggtatgat ggaattgctt atgcgttctt ttgcagctat cgttcttaca
     5581 ggaatgtggg gatacccagg agcagcagca gcttctcctt tagcttggat cggttctgtt
     5641 gccgtgttgc tttactctta tatgcgttcg atgaaacaat tgaaacacat gggtgaagag
     5701 gaacatttca cattagaaca tgcagaagca agatagcctt gattaaaaga aatcgttgcg
     5761 gctaaaaatg aaaactttta ttgaaaatat cttcttcgtt taccgaaaac aggtttttta
     5821 gataacaaaa aggctgtgac aaaaaatgtc acagcctttt ttcttttatt ctgtttttct
     5881 ttccgtggac tctactttga aataatcgat atgtgcatgc tggtattcta ataccgtgaa
     5941 acggaatgat gcaatctcaa tgattgttcc tgcttttatt tctttatatc ggctagaagc
     6001 aaagcccgca agtgtagtaa aattcgtttc ttcaaactct ggaatctcta catgaaaata
     6061 acgctggaaa tcatctaatg ttagtttgcc ggagatgata taagagccat ctgactgttc
     6121 cgctatcaat gcttcgtcca aatctgtctc atctcggatt tccccgacga tttcttctaa
     6181 aatatcttca atcgtcacta agccgcttgt ccctccgtat tcatctttta agatagcaat
     6241 atgcttaccc ttttttcgca tgatcgtcaa taattttttt atagggatcg tttcagttgt
     6301 tacgatcggc tcttcaatca actgttctac tgtcagctgg tcatctttat aagattgctt
     6361 gatcaaatct ggcaaggtga cataacctaa aacattgtct tttgattcta agataaccgg
     6421 atagcgagta tgtccttgtt caatcgaagc ttttatcgct tctttgacgg tttctgaagc
     6481 ttcgaatact tgcatggacg tacggtctac ttgtatatct tttgccaagg tatcatcaaa
     6541 ttcaaacacg ttttccaaat aataatattc ttctttggtc aactctcctt tttcataaga
     6601 attcaatgcg actaatgtca gctcttcttg agacaatgtc tcttctcctt cagatacgag
     6661 acgcacacct aatagcttcc ctagccctgc agctgaatga ttcaataccc aaataaaagg
     6721 aaacattact ttataaaaat aatgaagtgg tttaactacg aacaagacga ccttctccgt
     6781 attgacgata ctatagctct taggaagcag ttcgccaata accacatcga tatacgtaac
     6841 taaaataaat cccagcgcca cagagattgt actgctaata gccgaactaa aaggtagttt
     6901 accgatcact ggttctagta aagccgcgac agatccttca ccgacccacc cgatgatcaa
     6961 accggttagc gtaattccta attgactagc tgataaatag ttatctaaat ggtgtgtaac
     7021 atgaagagct agcttggcgt tctttacatt ttccttttct agttgttcca atcttgatcg
     7081 tctgattttc actaaagcaa attcacttgc tacaaaaaat gaagtaattg caatcatcaa
     7141 aaataaaata atgaaattga taaccatatt ctcccgcctt tctctttttc tattgtaccc
     7201 tttttctaca aaaagattga aaataatgcg tattcatatt taggaataaa aaaggagatg
     7261 cggcattttt cagccacatc tccttatcac ttcaaaatca ttgcgttact tgttgctaaa
     7321 cagctttttc atgacctctg ataaaaacgg tattcaaaag cttgcatcta cggcattaag
     7381 cccaaacaga tgaaaaacat gagaagctgt ttttatctgc tcgttcttac tgcttgttgc
     7441 agtacagctt tttcatgacc tctgataaac ggtgttcaag tagctgacat tcgacattag
     7501 ttcaggtcaa agcgctactt tcacaaccgc tctttcaacc atgttttccg agtatttcca
     7561 atgataagcg gaacagtttc atgttttact tcgctgtact ctagcccaaa ccatgtttct
     7621 ggcgaggtag cgattttttt gattgccagt tttgcctgca tgatttgacg ttgccatttt
     7681 cctagagttg tcacattgga aactacttca tcaatcagga caaattggaa atcgccaact
     7741 tctcgccctg gtgtcagaga gtatctttgt ggctgttttg gcaaacggcc ttgtttcatc
     7801 aaatcatgga tgacttggcg aacatatacg ttgatttcct gttggaccct gaaacctaag
     7861 aacagattca cttggacaat aaaatcagtg tccatcatat ctacttgata ttctttcgta
     7921 tatggctcat ccgtcacttc cacatgaaca aaccaataga ctcgtgctct tttaggccgt
     7981 ttatctaaaa tcgaatagat gaactgtcgg ccaactttat cttcagccat atcaggaacc
     8041 aagaagacca catttgtctg atagattggt aaagaagtat catcacgtaa ttctctaagc
     8101 tgcgggatat aatctctcaa agacacatcc tcggttgacg attcgcgaat aatgttccct
     8161 tgttcccaaa taaacatcac gactaagatg atcaaaccaa tcagaacggc tacaaaaccg
     8221 cctcggaaga atttgacaac acttgagata aagaaaacga cttctatcgc accgaagaaa
     8281 aaggtaacta aatatgcaag ccaacgagaa tgcccatttt ggataagata aaagtaaagc
     8341 agtgctgttg tcatcaacat cgtcacagtg atcgatagac cgtaagcagc ttccatatga
     8401 tgagacgttc ggaatgtgac aaccactaga gaacaggcga tccataaaat cagattgact
     8461 gctgggatat acatttgccc gatactgttc ccaggataca tgatctttaa ccgaggcagc
     8521 agtttcaact tgattgcttc tgaaactagc gtaaacgaac ctgtaatcaa tgcttgcgaa
     8581 gcaatgactg cagcgactgt tgcaaaagca acgccgatca cgatccaact ttgaggcatc
     8641 atttggaaga atggattcag gttcttgatt tgctgtgctt cagggttttg ataaacattc
     8701 aacaaccacg cagcctgccc aaaataattg ataaccaaac aaattttgac gtaaggccag
     8761 ctcagacgaa tatttcgttt gccgacatgt ccaagatcgg aataaagcgc ctctgcacct
     8821 gtcgtagcca ggaaaatatt tccaagaatg aacaagccta atttgttatc tgcactaaaa
     8881 agcagctgga tagcataata aggattcagt gcacggataa ctgtccagtc ttgactgaag
     8941 ttcattaatc ccattacgcc taaaaaagta aaccaagcga acatgattgg tccgaatgct
     9001 tttccgacaa tatctgtacc aaagcgttgg accatgaata aaacaaaaat aataactaaa
     9061 gtgataatga cgatcacgtt ctggttatta ccgaaccggt caaaaaactg cggaattcct
     9121 cgcaagcctt caatcgcagt cgttaccgtc acagcagggg tcaatacccc atctgctagt
     9181 aaggcagctc ctccgatcat tgcaggaatg atcaaatatt tcccaccttt tcggacaagt
     9241 gtgtagagtg agaaaattcc accttcacca tggttatctg cattcaatgc aatcacgaca
     9301 tatttgattg ttgtcagtag agtcaatgtc caaaaaatca atgagactga tccgataaca
     9361 aaatcaggat tgattcctga caatccgcca ttatcttcaa caatcgattt cataacgtaa
     9421 agcggacttg tcccgatgtc tccgtagacg actcccatcg ctacaagcag gccagccatt
     9481 gatatctttt tggtattgtg cgttgttgcc acgtttttcc ctcatttctt gttatatgga
     9541 tatcctttag gtaagcttga atgatagatg atattcttat ccatgacacc cgctttccta
     9601 aattgcttct aattatccaa gtaacacact gaagtgtcaa cttatttgaa taaaattatt
     9661 ctttctttgg acgttctctg atacgtcttg ccacaaatga ataaagagca aggcaaaaaa
     9721 ttgcacccaa taatgctggt atcaaataaa aaccgccgag ttccggtccc agtggtccta
     9781 gtaaaaattc gccgagccaa ctacctaaaa aaccgataat gatatttcca gatacgcctc
     9841 ccgggacttc ctttcctaaa attgcgccag ctatcaaacc taatataccg ccgataaata
     9901 acgaccataa aaaattcagc atctcctttc cctcctttat ccatatttct cacttttatt
     9961 ttacgcttta ttcagaagga ctccaaaaat atgcgccaag aaactccaga aaaaaagaag
    10021 ttgtaacaaa agtgttcagc ttatttccgt agaagctgct tctggaacac cgtgaatcag
    10081 aggttgtgaa atcagcggtt tgacctgagt attagagaaa caaacggaaa aatagttcct
    10141 catattttgc cgttttttga gctaatatcg agggacagct gattgaacat cgtttattgg
    10201 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa cagccaagta aaaacagctc
    10261 ctaatgtttt taacttggct ggacttatta ccgcagatgc aagcttttga acaccgttta
    10321 ttcgaaaaaa aaggactgtg acacggcttt tgtcacagtc cccttttttc gaataattat
    10381 tgtccccctg tcaccttcac gatcacaagt acattattcc tatgaattaa attatttttc
    10441 ttcatttttc gttgaaccat cttcgttcaa cattgctttt cttgacagat ttacgcgtcc
    10501 ttgtttatcg atttcagtta ctttcacaag gatctcatca cctagtttaa caacatcttc
    10561 gactttattg acacgatcgt ttgctaattg ggaaatatgg acaagtccat cttttccttt
    10621 gatcaagttg acgaatgcac cgaatttttc gatacggaca actttcccta gataaacttc
    10681 accaactttg acttctttgg tcaaatcttc gatgatcttg atagcttttt tgatcatttc
    10741 tgcatcagct gaagcaatac ttacttttcc atcttgatcg atatcgattt tcacaccagt
    10801 ttcatcgatg attccgttga tcgtatcgcc gcctttaccg ataacatctt tgattttagc
    10861 aggttcgatc tggatcattt cgatttttgg tgcatattgg cttaattctt cacgtggagc
    10921 agcaatcgtt gaagtcaatt cttctaagat ttccatacgt gcttgttttg cttgagttaa
    10981 tgcttcagtt aggatttgtt ctgtgattcc ttgaatcttg atatccatct gtaaagcagt
    11041 gataccatct tttgtaccgg caactttaaa gtccatatcg ccaagatgat cttccagccc
    11101 ttggatatca gttaggatcg tatagttttc accatcagaa acaagtccca tcgcaatacc
    11161 ggcgactggc gctttgattg gtacacctgc atccatcaat gctaatgtgc cagcacagat
    11221 acttgcttgg gaagaagaac catttgattc caatacttct gctactaaac ggatcgtata
    11281 aggaaattct tcttctgaag ggattacttg tgctaacgca cgttcaccta atgcgccatg
    11341 tccgatttcc cgacgccctg gagagcctgc acgtcctgta gaaccaacag aaaattgagg
    11401 gaaattgtag tggtggatga atcgtttgct gacttccacc cctaaaccat caatgatttg
    11461 gtgctctcct agaggtgcga gtgtacaagc tgataaagct tgtgtttgtc ctcgtgtgaa
    11521 caaacctgat ccatgtacac gtggcaataa gctgacctct gatgacaatg gacggatttc
    11581 atccaattta cgcccgtcag gacggatctt atcgatggtg atcaattcac gtacgacatc
    11641 tttttcaaga tcttctgtga tttgtttaac ttctttcaac aagtgatctt catcttcatg
    11701 acctgcaaat ttctcagcat aagcttcgcg gatatcgatc ttcacctgct cgatattatc
    11761 ttcgcgagca agtttttctt cagtcattac tgctgctttc attgtagcgt aagaagcatc
    11821 aaagatttct tttttcaata cttcatcaac ttgcagtaaa gtcacttcca ttttttcttt
    11881 ccctactgct tgaacgattt cttcttggaa agcaactaac tctttgatag cgtcaaaacc
    11941 aaacagcaat gcaccaagca tgtcttcttc tgaaacttct ttcgcgccgc tttcaaccat
    12001 attgatggct tgtttcgttc cggcaacagt caattcgata tctgtttgtt ctgcttgttc
    12061 tactgttgga ttcaagacgt actcgccatt tacacgacca acttctacgc ctgcgattgg
    12121 gccgtcaaat gggatatctg agattgatag tgctaaagaa gaacctagca ttgctgccat
    12181 agctggcgag cagtctgttt ctacactcat cacgatgttc gttacttgga cttcattacg
    12241 gaagccttct gcaaacatcg ggcgaattgg acggtcgatc aaacgggcag tcaatgttgc
    12301 ttccgtactt ggacggcctt ctcgtttgat gaaacctcca gggattttcc ctgctgcata
    12361 cattttttct tcataattga tcgttaatgg gaaaaagtct gtatcttttg cttctttaga
    12421 ggccacagct gcacttaaga ctactgtatc tccataacgg actaaaacgg ctccgtttgc
    12481 ttgttttgct agctgaccga cttcgatttg taagggacgg ccgccccatg tcgttttgaa
    12541 tacttgtttt tctgacataa cttctccttt tccttctcgt gaaagcaaga cgctactaaa
    12601 caaatgaaaa ctgccgaaag ccgtcttttg agcagctttc atttggttag taggagtcca
    12661 tctagcttga tcacggaatt ttacttaatt gatatacgag taaaaaaagt gagattcatg
    12721 tgaatcccac tctttttgac taaaattaac gacgcaagcc taaacgtttg atcaattcgc
    12781 ggtaacgttg aacgtcagtt ttacgtaagt aagctaacaa gttacggcgg tgaccaactt
    12841 ttttcattag gccgcggtat gaatgatggt cttttttgtg cacgcgtgca tgttcattca
    12901 agtggttgat ttcttcagtt aatacagcga tttgtacttc tggagaacca gtatcccctt
    12961 catggcgagc gtattcgttg atgatttcat tcttgcgttc ttttgaaatt gccatttctt
    13021 tcacctcttt cgattattcc cctgcgactg agtaaaacgt tggtgattcg cttaaccaag
    13081 tggcaggtca tgtgcctaga gcacacagct atactttacc tgaaaccggg ttgaaaatca
    13141 agtagttaat cattaagaaa aggtagtttt caaacaatct tactactact tttccatttt
    13201 tgtggtaaac tataatgcga aaatagactt gaaacacagt cttttaagaa aggggtacat
    13261 attccatgat tacaatggat gatatcattc gtgaaggaaa tccgacctta cgcgaagttg
    13321 caaaagaagt ttctcttcca ttaagcgaag aagatatctc tttaggaaaa gagatgcttg
    13381 agttcttaaa aaacagccaa gatccaatca aagctgaaga actacactta cgaggcggtg
    13441 ttggcttagc tgctcctcaa ttagatattt ctaaaagaat cattgctgtt cacgtaccaa
    13501 gtcctgaccc agaggcagat ggaccttctc taagtactgt tatgtataat cctaaaattt
    13561 tgagccattc tgttcaagat gcttgtttag gggaaggtga aggctgttta tctgttgatc
    13621 gagaagtacc aggatatgtt gttcgccatg ccaaaatcac tgtgtcttat tatgatatga
    13681 atggtgaaaa acacaagatt cgtttgaaga attatgaatc gatcgtcgtt caacatgaga
    13741 tcgaccatat caacggtgtg atgttctatg accacatcaa cgatcaaaat ccatttgcac
    13801 taaaagaagg cgtattggtg atcgagtaga gaattggcag gttccttcga tactatgcta
    13861 caagaaagct ttataaaaaa ggggagtgct caaaagctgc acttcccttt tttatgtttc
    13921 tccactaatc gaaatttaga tagacatcta gaaatcgcaa ttccaaaaaa ttctgtgtat
    13981 tggatacgca tcttttctta ttttttctta tttcttccat atgggtgttt atctcagaga
    14041 tgatagaata gtttctagga taaaaagtag cagctacgat gttatccttc gtagaggatt
    14101 cctgcttcag ctagtttttg tttgatgttt ttcagcatat gcttttctgg gtagcggatc
    14161 gtatgcagat ggatgccgcc tgttaattcg gataacaaag tagcattact tttttgataa
    14221 cgtctcataa aggaatcgat atcttgtggc gttttgatgt gcaaagttcc tgctaactca
    14281 ccgtaaaggg gatgttccac aattacatca atgatttcac caccattttc aacgattagt
    14341 ctcagttctt cttctgtttg atcttttcca tgctggacag cgattttact gatgtgccca
    14401 gtattggttt cttctgtttc gaggatataa cctcttgctg ttgccacgat acttttacct
    14461 gcagctcgta gtaaagcaat atcgcctaca atgatctgac ggctgactcc aaaagttttc
    14521 gcaaacttgc tagcactcac tggtttttct gtatttgcca aggtttgcat gatttgtttt
    14581 cgccgtgtct ctccttcgat cacacttatt cctccttcat tttgttttgg tattcgcgcg
    14641 agtgtttcat caaatcaaca tacgtgtctg ttattgtttc cttatatccc ttatttttca
    14701 gcagactaac aactttatcc aatacttgct gctctctttt tgcatcataa actgcttggt
    14761 tttcttcttt tttcacttgt cctattttag ttaccgtatc cattcttttt tctaataaag
    14821 caaccaactc tcgatcgatc atatcgatct tatgacgtaa tgtttcaaga gactcttctg
    14881 ttagttcttc ctctactgtc ttgatgatac gagcaggatt tcctgcaatc actacattgt
    14941 cgggaaaaga tttggtcaca accgaacctg cgccgactac tacgttgtcc cctagagtga
    15001 cacccggcgt gacgataact cctccgccta accaaacatt attaccgatt ttaatgggtt
    15061 ttgcgtactc cagaccgctg ttacgtttca ctggatgtag tggatgcgtc gccgtgtaaa
    15121 gctggacatt cggagcgaac atgcagttat caccgatttc aatcgtgctg acatctaaaa
    15181 atgtacaatt gaaatttgca taaaaattct ccccaacaaa tatattatat ccgtaatcaa
    15241 aattgataac tggctccata tagatttttt tccctgtacg gccaaaagtc tctttcaaca
    15301 attgggatcg cagttccgct gattctgctt ggttgatgat ttggctttga cttcttgcaa
    15361 acatacggtc ggcaaccagc tcaggatcat tggcaaaata aagctcgcct gcaatcattt
    15421 tttctttttc ggttttgaat tcagtcataa tctgctccta attcttgtat ttttttgaaa
    15481 acaaccgctc cgtcttcttg aataaacgta taaggctccg ctaaataaac aggcgtttga
    15541 ttgattacta agattttggc tgacggctgg cgaaactgta ccagatcaca aaacggatga
    15601 acttgaaaac tcgttccaac aatgacgatc agctctgctt ggctgacggc ataagccgcc
    15661 tgctccatga ctccatcttg aaacccttca ccatataaca cgatgtctgg gcgtatttgt
    15721 cctccgcatg cttgatgttt gtcgctgtga agatattctt tccagtctac cgtttgttga
    15781 cattttcgac aatgacattg atacagactc ccatgaaaat tgacgagttg cgggctttta
    15841 gcctttgcgt gcaaaccgtc gatgttttgg gaaacaaccc aaacattttt ttctttcgct
    15901 agatgtgcta tttccaaatg aatgatattg ggttttgctt caggatgata aatctttttg
    15961 acaaattgat agaatttatc cggttcattc accattgctt gatgactcag caagtattcc
    16021 ggctgctcca tcccgtggta gattcctgac aaagatcgat agtctggcac tccagaaggt
    16081 gtggataccc ctgcaccggt caaaaatgta atttgctgat aagctaatat ctcttttgct
    16141 gcttcgtcta ctgttaattg tttcatgttt tgtcacctca ctttccatta tagcccatac
    16201 tcgaacaaat ttattgttga aaagtcagaa aaatgggaat aaaaaagtgt tatgggcatt
    16261 tgagcaattt atcacaatgt tcactgacaa aagaatgaaa acgtgttaca atactgctgt
    16321 ataaaagtga ggtgaatcga tatgttacca ttctttattt attggggcgt tattctggct
    16381 tgtatcgcct ggttagcgtt aagcgtttat ttctctgttt tttatcttgt acgcaaagaa
    16441 aatggaaatc tttgggcttt tgctttattc aacgtgattg ccgcaattgt tttagccatt
    16501 acattagccg tatatcgaac atggggctgg ggaatcaccc aatactcaag tttgatttat
    16561 ctaatattag ccatttatgg cgtcgttgtt cttttgcaag cgatcctagg acgtgagcca
    16621 aagaaagcgg cagcttaaat gatcgagatg gaactggaca caggaaattt tctgttctag
    16681 ttcttttttt attgtattac atacattttt gtgtataatt atactatcgt ttgcaatgga
    16741 tagatgattc acattttgat tgttttttcg gtaaaagtaa agatttctat atttatcagt
    16801 attttttcaa aaaccagcag ttatagattg acaaagcctc tcgagtatcg taaacttttt
    16861 ttgtataaat aactgaatac gagatgcctc aatcaatgag gtagaggtcg cgagaatcat
    16921 taaccctgtg gagtgaagca aacatggaga agcaggaata gggaggatcg ccgaaatgtg
    16981 cacttttttg cttggagtgt atgttgggac gcaagttaag agcttgcgga ctgtcttagc
    17041 agtgatgcta agttgcgcta tgttttgtga gaggtttatc accttatgga attttagcgg
    17101 cctttttata tctataaatc ggtcgctttt tattttttca gataaagctt taccgcattt
    17161 catctagacc gctcgtgtat catataatca gaaagggaga aaaaaatgaa aaaaaatatg
    17221 gtttcagttg ccgtactatt tgcttttgtc ttctcactat tcagtgtggg atctctggca
    17281 aatgcagatg aaaaaacacc gagcgatgag tttcgcgtag gtatggaggc tgggtatgca
    17341 cccttcaact ggtctcaaca aacagatgag aataatgcct tgccaattca aggccaaaat
    17401 agttacgccg gcggttatga tgttcaaatc gctaaaaaag tagcagatgg tttagggaaa
    17461 aaattagtca tcgtccaaac gaaatgggat ggtctggctc ctgcccttca atcaggcaag
    17521 atcgacgcga tcatcgccgg aatgagccct actgctgaac gacgaaaaga aattgatttt
    17581 accgatcctt attacgaatc acaattagta gtagtagttc aaaaagatag caaatatgca
    17641 aaagcaaaaa gtttagcaga tctttctgga gcaaagatca ctgctcagtt aaatacattc
    17701 cactatactg tgatcgatca gataccagat gtgcagaaac aacaagcaat ggataatttc
    17761 tcagcaatga gaacagcttt agcttctgga atgatcgatg gttatgtcag cgaacgtccg
    17821 gaaggtgtaa cggcaactag tgtgaacaaa gacttggaaa tgcttgaatt cagcggtgca
    17881 gatggcttcc agacaaaccc ggaagatgtt cagatttctg ttggtatgcg taaaggcgac
    17941 ccggatatcc aaaaagtaaa ccagattctt tctggcatct ctaacgatga acgaaccaaa
    18001 attatggacc aagcagtcaa agatcagcct gctgcaactg atagtgaaga aaaacctggc
    18061 atcatttctg atttcactac gatttggaaa caatacggca atatgttctt acgaggtgct
    18121 ggacttacct tgttcatcgc attgatcggg acagttgtcg gtactacact tggattactg
    18181 attggtgtct tccgttcggt acctgaatca ggaaatgcac tgactcgctt cttccaaaaa
    18241 atcggaaatg cacttctttc tatctatgtc gaagtattcc gcggaacacc gatgatggta
    18301 caagcaatgg tcatcttcta cggtctggca ctcgcttttg gcatttcatt gaaccgaacg
    18361 attgccgctt tgtttattgt ctctctcaat actggagctt acatgacaga gatcgttcgt
    18421 ggggggattt ttgcagtaga tgaagggcag ttcgaagctg cgcaagccat tggtatgacc
    18481 catggccaaa cgatgagaaa agttgttatt ccacaagttt tacggaatat cttgccagca
    18541 acaggaaatg agtttgttat caatatcaaa gatacagcag ttttaagtgt aatcggcgta
    18601 gctgatttgt tcttccaagg aaactctgct tccggtgcga atttccaatt cttccaaaca
    18661 tttacgatcg tcgggatcat ctacttagtc atgaccttta cgatcaccag aatcctgcgg
    18721 gcggtagaaa agaaaatcga tggtccttca gcttatacca agcttgaaga aatcgacaat
    18781 tcaaatttgc aggaataagg aggaagaatc atgaatgaaa aaattattga aatcaaacat
    18841 ctaagaaaaa gcttcggtga aaatgaagta ttgaaagata tcagcgtaac agtcaataaa
    18901 ggtgaagttg tgacgatcat cggttcttcc ggttctggta aatctacttt cttgcgctgt
    18961 atcaatttac tggaaaaacc aacaggcggc gagatcattt ataatggaga aaatgtatta
    19021 gctcctaaat ataatttacc taaatatcga acgaatctag gtatggtttt ccaatccttc
    19081 aacctgttca acaatatgaa tgtcttggaa aactgtatgt ctggtcaaac aactgtcctg
    19141 aaacgagata aagaaactgc caaaaaagta gcaatcgaaa atctggaaaa agttggtatg
    19201 gatcgttata tcgaagccaa accagcacaa ttatctggtg gacagaaaca gcgtgtcgca
    19261 attgctcggg cattatcaat gaatccagat gtattgctat tcgacgaacc tacttcggcg
    19321 ttagaccctg aaatggttgg cgaagtgctt aatacgatca aagacttagc acatactggc
    19381 ttgacaatgc ttatcgtgac gcatgagatg gaatttgcaa aagatgtatc tgaccgtgtc
    19441 atttttatgg ataaaggtgt gattgcagaa gaaggtacac cagaagatat ctttgtccat
    19501 ccgaaagaag aacgtacaaa agaattcctt tcacgtattt taaatgctta ggatcaatag
    19561 ctgattggga caaagagctg cggtgtttac cgcagttctt ttttatgaat tactcataaa
    19621 aggtaaattt ctgaa
//
LOCUS       DADVXV010000056        19086 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.057, whole genome shotgun sequence.
ACCESSION   DADVXV010000056 DADVXV010000000
VERSION     DADVXV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.057"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(387..1853)
                     /locus_tag="KB969_001863"
     CDS             complement(387..1853)
                     /locus_tag="KB969_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6869832.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="KB969_001864"
     CDS             complement(2144..4228)
                     /gene="cadA"
                     /locus_tag="KB969_001864"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBB6869833.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4753..5112)
                     /locus_tag="KB969_001865"
     CDS             complement(4753..5112)
                     /locus_tag="KB969_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBB6869834.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5142..5483)
                     /locus_tag="KB969_001866"
     CDS             complement(5142..5483)
                     /locus_tag="KB969_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869835.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5480..6154)
                     /locus_tag="KB969_001867"
     CDS             complement(5480..6154)
                     /locus_tag="KB969_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBB6869836.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="KB969_001868"
     CDS             complement(7330..8628)
                     /gene="asnS"
                     /locus_tag="KB969_001868"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBB6869837.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8668..9858)
                     /locus_tag="KB969_001869"
     CDS             complement(8668..9858)
                     /locus_tag="KB969_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6869838.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9879..10406)
                     /locus_tag="KB969_001870"
     CDS             complement(9879..10406)
                     /locus_tag="KB969_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBB6869839.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10453..13242)
                     /locus_tag="KB969_001871"
     CDS             complement(10453..13242)
                     /locus_tag="KB969_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBB6869840.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13389..13589)
                     /locus_tag="KB969_001872"
     CDS             complement(13389..13589)
                     /locus_tag="KB969_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6869841.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14042..14362)
                     /locus_tag="KB969_001873"
     CDS             complement(14042..14362)
                     /locus_tag="KB969_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869842.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14865..15983)
                     /locus_tag="KB969_001874"
     CDS             complement(14865..15983)
                     /locus_tag="KB969_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869843.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16454..17761
                     /locus_tag="KB969_001875"
     CDS             16454..17761
                     /locus_tag="KB969_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBB6869844.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17882..19081
                     /locus_tag="KB969_001876"
     CDS             17882..19081
                     /locus_tag="KB969_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBB6869845.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
BASE COUNT         5470 a         4026 c         3323 g         6267 t
ORIGIN      
        1 aataaatggt gttcaatcag ctgaccttca gcattagctc aaaaagcggc aaaatatgag
       61 gagctatttt tccgtttgtt tctctaatac tcaggtcaaa tcgctgattt tacaacctct
      121 tccttaaacg gtgttccaaa gcttgcatct gcggtaataa gcccagccaa acgaaaaata
      181 tgaggggcta tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac
      241 ctctgattca cggtgttcca gaagtagctt cttcgaaaaa caagccgaaa cttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttgt aacaagtatt tctattttaa ggctgaacca ctgtttctgg ttcagtgatt
      421 tctttgtttt tgtctcgacg agcaattgct ggcaagatca tacctaataa gatcaagacg
      481 attggtgtga tgatattcgt aaataattgg aaccaccatg ctttaggatc agcagtataa
      541 tctacttttg gcaccattcc taggatacat gcaaacgcag tgaaggcaaa gcaccaagca
      601 ccaaagataa aaccgatttt tggattttta acaaatttat attcagaatt gaatttctta
      661 taagctttat tcaacatcat atatgccaag aacacccata ggtaacgcat tggcatgaca
      721 actgagttca agttcgtcaa ccattttact aattcattca tatctttgat accaaaaatc
      781 ggcaacaaaa taatgattcc tactagtata cctgtcagaa gataaccatt caccaatgta
      841 cctttacgat tacgtttacg tagccagttt ggtacaaatt ctggatccgc atctgctaac
      901 aagattttta gtggtgcatc aattgaaaag gctaatgcgg agatttgtcc aatcatgttt
      961 gtcaatgcgt aaatgatcat caatgagtta ccgataccat agtaattacc taaaatttga
     1021 aaagcactgt atgccccatt tgccatcaag tctttaggaa tattatcact agcaaacagc
     1081 atacccattg cgactgagcc taatacagca caaatcccta ccattgctgc taagaagatc
     1141 atccctttag gaaattcctt tgcaggattt cttgtagagt tgacataagg ggatattttt
     1201 tccgcccctc caactgcaaa tactagcatc gaaacggttg tgaaataact gaaatcaaat
     1261 gttggaatat atgttttcac ttgattcata tgtggtgtgg caaattccat cgttggattg
     1321 atgaacggtg ccgttacagc taaaagaata aataagatcg acatgacgaa catcgctgtt
     1381 ccggccagtc cgccaatcac tttcaaagta gaaagtcctt ttgttgataa atataaaaag
     1441 gcaagaaata taataagtga aataactgct accatttgta ctgacatcgt atttacgata
     1501 tttccatttc cttggactgc ccaaccacca gcaatcagaa ttgcttgagg cttttgtgcc
     1561 aaataaggaa tatggacgac ccagtaagtc caagcggcat agtatgccag tcgtttatta
     1621 gatgtcgtat tttcgaccca tgaactgacg cctcctttac tatccttgaa ggctgatcct
     1681 aattgtccaa cgatcaatgc gtatggaata aaataaatgg ccaaaatcaa tagccaagag
     1741 gtgacaactg atactccttg ctgagcatag ttattaacta cattccccat gccccaaacc
     1801 atgttaaatg caattaacgc aacagtaaac cagcgtaatt gtttgttgtt cattcgttct
     1861 ctcctttatg ataaaaattt gttatccaga tgtaatcata ttcaattttt aacaaactta
     1921 caagacagtg ttattttatg tgtgtattct tttatttaat acacatcgtt ttttcatatt
     1981 ttttccatca aaaaaataag ttattttctt ttatttcatt gaccttattg aatttcaagc
     2041 tattttgaat tttctgcaaa attaaaaaca ttagttattt tataatccta tctattttct
     2101 ttacattttt cattaagaaa aggatataaa aaaaagagga cgttcattcg tcctcttttt
     2161 ttacatgcaa gcttcgcatg gcattcaaaa cagctaatac tgtcacccca acatctgcaa
     2221 atactgcatc tcccattgat gcaaaaccaa aagcacctaa ggcaagtacc aaaattttta
     2281 tcccaatagc aaagacaatg ttttgtttga cgattttcaa tgttttcttt gctaaatgga
     2341 ttgcttctgc aatcttcgat ggttgatcat tcatgatgac tacatctgct gcttcaattg
     2401 cagcatcgct tcccaatcca cccattgcga ttcctacatc tgctcttgct agcaccggtg
     2461 catcgttgat tccatctccg acaaatgcgg tctttttatt gtttctttgt aagatttcct
     2521 ctaaccgctg cactttatct tcaggaagca attcgctata tatcttgtcc acgcctactt
     2581 gcttcccgat atgatcagca atttttttcg agtcgcccgt caacatgact gtgttcttca
     2641 caccagcctg ttttaattga accaatgcgt ctacggcatc ttctttcaag gtatctgcaa
     2701 taacaagata accactgtaa ctttgatcga tcgctagata aagcaatgta ccgatttctt
     2761 gacttaaagg aaaagagatt tcaaatcttt ccatcaattt gtgattacct gctaatactt
     2821 gtttgccatc aacttcagct aagatccctt cacctgcaaa ttcctggata ttagttgttg
     2881 gtaaaagcgg acctgcgtag ccttctaaaa cagattgagc aatcggatgt gtagaaaact
     2941 gttctgcact cgcaatatat tgcatgaatt tctttggatc gatttttgta tcgatcgtct
     3001 ggatcgaaaa gtcacctttc gttaatgtgc cggttttatc gaataccact gtctcggttt
     3061 gcgcaagcaa ctccaagtaa tttgaacctt ttactaatac accgatttta cttgcgcctc
     3121 cgataccgcc aaagaaacta agtggcacgg aaatcactaa tgcacatgga catgagatca
     3181 ctaaaaatgt caatgctcga tagatccatt cagaaaacgc cgctccagaa acaacaagtg
     3241 gaggtaaaac agctaataaa acggccaatc ctacaacgac tggtgtgtaa tagcgcgcga
     3301 atttagtaat gaaattttca gctggtgctt ttttactgct ggcattttct actaattcta
     3361 ataatttgct gatagtagaa ttttcataag atttttctac ttgaactaaa aatggtttat
     3421 ttttattgat aaatccgctt aatactgttt caccaacata tacagattta gggactgatt
     3481 ctcctgtaag tgctgacgta tcgactaatg attctccttc gatgatcgtt ccatctaacg
     3541 gtacacgttc accaggcttc acaagtacaa actgaccgat ctgcacgtct tcagggttca
     3601 cggtcatcaa tccttccgtc gtctgcacgt gagctgtttc tggacggatc gccatcaatt
     3661 cgcgaatcga ttttcttgaa tgactgactg ccaatccttg gaaatactcg ccgatttgat
     3721 aaaatagcat cactgctacg gcttctggat attcaccgat caacatagcg ccaatcgtag
     3781 caacagacat aagaaaattc tcatcaaaga tttttccttt gacgatattc atcactgcct
     3841 tcttcactac atcatatcct atcagcagat aaatcaataa ataccctatc aagcgaattg
     3901 gttcattaaa atcaaataat agcaataaag cgatacctgc aagggaaaat aaaatccgga
     3961 acagcgtatt tctctctttt tcatttccat gttcagatac tttttcctta tctatttctg
     4021 ttactttgac atctggttct aattccttca ctactttttt tgtttcttgt tcaatcgtag
     4081 ccaaatgatc ttcctctgcg tcaatcgtta gttttccaga agtgaagttt accgttgctt
     4141 ccttgactcc attgatcttc tgaactcctt tttcgatttt cattgcacag ttcgcacaat
     4201 ctaaaccttc taatctgtaa cttttcattt taatgacctc ctcgcctcaa catatgaaca
     4261 tctcttcata actaattata aatgaatggt tattcatatg tcaaggtatc cgaaagaaaa
     4321 aatgaaaaac atctgcatcg gaaaatttct tccatacaga tgttttggct tattctttct
     4381 ttttctcttc gatcattgcc cctgctctta tccaacccgc acttgccttc ttgatcttga
     4441 caggatagca actaagtttg aagcctgttg ctggcaattt gtctaaattc attaattttt
     4501 cgataggaca atatcttttt tcaatccctg caaaatgtcc ttcccagata ttcgaagctc
     4561 cactacgctt tcaaaaatat agaaagagtt ctttaatgaa aattatttca actttccata
     4621 aacagtaatc ccatataaat aaaagacgta aaagtcacat gggagaactt atacaggaaa
     4681 acacatagag tcaggtgaaa tacatgtatc ccacctgact ctatgcgttt tctaaccttt
     4741 attattctct ttttatacaa tttctgcacc gaatggcatc aacgccaatc gagcaagttt
     4801 gaaagattgc ttggcaaaag gtatccctat gatcgtgata catagaagga tgccgctgac
     4861 gacatgtgcg agagcaattg gtaggcctga aacgatcagc cagatgatat taacgatcaa
     4921 tgacatgcca gactggtgat aaattacttc tttgccaaaa ggcgcaaaag aaagggaggc
     4981 gatcttaaaa cattgcatac cgattgggat acctatgatc gtgatacacc aaagtatccc
     5041 cgctgctaac cagctaagac caccgattag tccgccgaat ataaaccaga tgacatttcc
     5101 taaacaactc attgtatttc tccttctatt actgtttttg attaaaactg ggcaaaaatt
     5161 gattttattc ttcttttttt agcttccagc atcaagtatt ctgcaaattt tttttggatt
     5221 tcttccgtat tttcttttgt tactaatgtg tgttggatta gttttcctga tggtcgctga
     5281 tccacccgtt cttctgactg ttgcacgtcc gcttgcgcaa atccgataat ccgtttttct
     5341 tttgttacag caacgagcaa tagtttattc ttatcattta ggtcagctgc cgtttttgct
     5401 tttacgaatg attctggatg atcagtaatc agctgattga tttgaggtaa atcttctttt
     5461 actgcccacc gtatttccat catttctcac ttttctttcg ctcattttta tctccactaa
     5521 aaaaatcgac tgcggcaatt gcatctatcc agctttgtgc aatgatctca tgtccgccaa
     5581 tcgttgggtg gaccccatct tctcttgtat atttcgaaaa accataagca atccctaaag
     5641 cattgaatat gccatctaaa ggaaccagca atgcgccata ttccttagca agtttacgaa
     5701 caatttggat tttagggtct aagtctttac gccagccatg acggtcgtcg gttataggaa
     5761 gtacaaacgg ctccatcaag atgatgttgc agatttccgc tgtttgaagt tcatttagta
     5821 attttcgata aacggattca aattgctgcg cagatttctc agttccgaat atagcctgat
     5881 cgctagtatt atgccaggta tcattgattc cgatcaaaat cgatacatag tcaggttgta
     5941 aagctaaaca atcttcttgc cagcgtactt gcagatctgc aattttgtct cctcctatcc
     6001 cacggttcat gcattcaaat ttcatcgttg gatattggga gattagtttt ccggcaatca
     6061 aaagtggata acctttacct agatcagttg cttctgctcg gtctcttcct gcgtctgtaa
     6121 tgctgtcacc gataaataat atacgttttt tcatttgtca aaaactcctt tttgaataaa
     6181 acgatgattt tcttccttat attatcccat aagccctatc aagacgaaag agaaaatata
     6241 tgtataaaaa atgacaccag cctagtccct tcaatcaatt gaatgaacgc tcatcaagtg
     6301 tctagttttt tatacttttt ttcttaacgt gccggattcc ccttgattcc ttcgttgttt
     6361 ggtccagaga aatcgatcac acctaagctt ccgtcaatca gaccactgat gacgccatca
     6421 gaacatatat ttataggctc atctaagact tccagtaaat gttcttttac taatatctct
     6481 tctagattgc ttgggataga ttggtcataa ctttatctgg tccgatgatt tcaaggatga
     6541 attaaactta catatggatc attgcatgct gaaaatacgg acctactcca tcttcgaatg
     6601 ttactattag tttgttttca ggtactagat gctgctttat ttcaacagca gaagcatcat
     6661 caaatcagat ttccatttga ataaccttct ttgtatatgt ttgattgatt gcgatttcgt
     6721 tatagaacct tgtgaatcaa atagcaattt cttttgcttt cttctcttgt ctgctggaaa
     6781 cttcctttat cccgtatttt aaaaaaagaa ctgcgagagt tcgcagttct tttttttaaa
     6841 taaacgttgc tctccggcca actcctcggt cacaagtcac aatagtcatc aaacatgaaa
     6901 aactgttttt tgaaattact ccttgtgact cggagctgaa cggcaggcgc acaacctctt
     6961 gatataaacg gtgttcaatc agctgaccct cgatattagc taaaaaaacg gtaaaatatg
     7021 agaagctatt tttccgtttt gtttctctaa tactcaggtc aaggcactga tttcacaacc
     7081 tcttccttaa acggtgttca aaagccagtt tctcggtatt aagccaaatt tatgcaaaaa
     7141 tgtggaaagc catttccaca aaatttttct taatactcga aactaaacag ctttttcaca
     7201 acctctccac taaacggtat tcaaaagctt acatctgcgg taataagtcc cgccaattca
     7261 aaaacatgaa cagctgtttt tgcttggctg ttctaattac ttgatgcaga acagcttttt
     7321 catcacctct tatggataaa ttcggttcaa caaacgtggg aatggaatag cttcacgtac
     7381 atggtcgata ccagcaatcc aagtgactgt tcgttcaagg cctagaccaa aaccagagtg
     7441 cggaacagaa ccgtatttac gtagatcaag ataccatgaa tattcttttt catccaaacc
     7501 gtgattacgg atttgttcta gcaagaaatc atagtctgtt gcccgttcgc ttccgccaat
     7561 aatttcaccg taaccttctg gtgcgatcat atctgcacaa attaccacgt cttctcttgt
     7621 tggatgtggt ttcatgtaga atggcttgat ggcttttgga tagtttagga taaagacagg
     7681 ctgttcgaat gaattcgcaa tgaacgtttc atgaggtgaa ccaaagtctt cgccccattc
     7741 gatgtcatca aatccatttt tcttcagtaa ttcgattgca tcatcgtaag taatacgagg
     7801 gaatggcaat tttgtataag tttttaagac ttctttgtct cgtcctagta catctaatgc
     7861 atattcgcaa tgatctaaaa cattttgtac taagaatgct acatattgtt cctgtacttc
     7921 taaactttct tcttgatgag tgaaagccat ttctggttcg atcatccaga attcgatcaa
     7981 atgacgtcgt gtttttgatt tttcagcacg gaaagtcgga ccgaatgaaa agacttttcc
     8041 gaaagccata gcagcagctt ccatgtataa ttggccactt tgagataaat aagctttttg
     8101 atcaaagtaa tttgtttcga atagatccgt agtgccttct ggtgcagaac cagtcaagat
     8161 cggcggatcg attttgacaa aatgatgttg attaaagaat tcatacgttg cacgaatgat
     8221 ttcatttctg atctgcataa tcgcatgttg tcttgaagaa cgcagccata aatgacgatg
     8281 atccatcaag aaatctgttc cgtgttcttt tggtgtgatc ggataatcgt ggctctcgct
     8341 taccacttcc acatttgtaa ttccgatttc ataaccaaat tttgaacgac tgtcttcacg
     8401 gatttctcca gttactaaca cggatgtttc ttggtgtaga tttttagctg tttggaaaac
     8461 ttcttccgac acttcgcttt ttacaactac accttggaaa aaggctgttc cgtctcttaa
     8521 ttgtaaaaat gcgatttttc cgcttgatcg cttatttgcg acccaagcgc cgattgttac
     8581 tgtttctccc acatggtttt tcgaatcgat gatttgaatt tgttccacgt atgactctcc
     8641 ttttatattc cttgaatttc ttcaggatta attttgactt ttactctcaa taaattgctt
     8701 gattctgcgt accgcttctt ctaacgtagc gcgatcagtg gcataactca tgcggacatt
     8761 ttctggtgcc ccaaagcctt cgccagtcac aagcgctacc cctgtttctt ctaaaagatc
     8821 ttctacccat tgtgtgacat tttcatactt acacatgcgt agcgtttctt ttacattagg
     8881 aaaaagatag aaagctcctt gcggcttttc aagagaaaca cccggcagtt ctgccacaag
     8941 cggatataac gtattcaggc gttcttcaaa ggcgttccgc atttcttcta ctgtatcttg
     9001 ctcacctttc aatgcttcaa cagctgcata ttgactgact gctgtcggat tgctagttga
     9061 ttgggaagca acagcgatca ttccattgat gatcacagga tttcccaccg cataaccaat
     9121 gcgccagcct gtcatcgcat atgttttaga cacgccgttg atgatgatgg tctgattttt
     9181 gattgcttct gaaatcgttg caattggagt aaactcattg ccattataaa ctaaacggcc
     9241 ataaatatca tcagcaacta tcaaaatatc attttttact gcccattcac cgattgcctg
     9301 cagttcattc ttgctataaa tcattccagt cggattcgat ggagaattga tgattacggc
     9361 ttttgttttt tctgaacgtg cttgttctag ctgttcaaca gtaactttcc agctattgga
     9421 ttcttcccct ttcacaaaga caggaagtcc ttctgccagt tttacttgct caccgtaact
     9481 gacccagtaa ggcacaggaa tgatgacttc atcttgcggg tcaaggatcg tttggaaaag
     9541 ggtatacaaa gcaaatttcg ctccgtctgt tacgactgtt tgtgaaggtt catagacaag
     9601 tccatagttt ttcttcagat aatcaacgat tgcctgtcga agctctggga ttcctgctgt
     9661 tggtgtataa tagctagctt tcccattgcg gattgcttcg attgctgctt cttggatgtt
     9721 ttctggtgtc gcaaaatccg gttctcccac agtcaaactc agcacatctc tgccttttgc
     9781 ttttaatgcc ttggcctttg ccgcagctgc caaagtgaca gacggttcta atcgttttgt
     9841 tctttttgat aactccatcc cattcattcc tttacctttt aaattccctt gattgtcttg
     9901 acttcatctc cagattcaaa gccaatcagg taataattca gtttcccatt tgtttctttt
     9961 cctactactt cccacacagg ctgatcatca tacatcccta aagcagcttt ttcgatttgg
    10021 atttcaggat gggccgcagc aattgtctgt tttgcttcgt tttcagtcag tccctttgtt
    10081 tgatccaata cttttacttt ttcaccagat ttaggaatga taacggcgat ttcttttcct
    10141 ttatcatttg tacctgtcag tgaaaagtat gtcttctttc gagtaaacca ataaaaatga
    10201 tcggtttcct caagatttgc atatttcttt gcgatttcta ctgcttcttt cttcgcctgc
    10261 accgccggac gactggaacg caagtaaaaa atcgagctga tcacgatgac cgctaataaa
    10321 aatacgatca agccaagtaa cacgcgatta atcgtttttt cctttgtctg ttttttcttc
    10381 aagggtcgtc gctcctttat cttcattcct tttcattata gcagatttta attatgaaaa
    10441 aagacagctc ctctaacttc cttcttcatt tttctttaag aattcatgga tatcctgata
    10501 gatttcctcc atagctagct ctttgatcgg tacttttttc ggtaatgcat ggatgatccg
    10561 tgcgccatat tttgcagtga ctagtcttcg atccaaaata agcaatacgc cacgatctgt
    10621 ctccgtcctt atcaagcgac ctaatgcttg gcgtaacttc aaagctgctt taggtacgga
    10681 ttcctggtaa aaaggattga tcccctctga ttctaaataa gcgttcctag ctttgaccat
    10741 cgggcgaagc ggattatcga agggtaaacg tgtgactaca acgatctgca aagcatctcc
    10801 aggcaaatct acaccttccc aaaagctgtc agcgccaaac aatacgcttt tttctgacaa
    10861 aatgaagcgt ttcaaaagct tctcccggct tccaccaaac ccttgagcta gtatttctcg
    10921 tcctttttct agcatagaca gatgcatttt ctgatagacc ttctgcaaaa catcatgaga
    10981 agtgaataac acaagtattg gccgatcttc ttgttcgatc agacctgtaa gtgctgtctc
    11041 taaataatcg atatatgctt gattgctgac ttgatggacg gcaggtgcct cttttggcac
    11101 atagatcctt gcctgtttct cataatcata aggagaggca atcactttaa gaggtgctgc
    11161 ttcaatgcca agcctcttag agagatagtg tcgattaggg ccgatcttca gcgttcctcc
    11221 aatataaaga atacgatcat atcgaggata ccaaacagtc gacggcaaca tagccgcttg
    11281 aaaatcatgg agatgaaaaa tcatctgctg cgctgtgttc ccaggaacga accaatggat
    11341 caaatgatct cgccagtctt ccagccattg atccatcagc aagtattgct tgtctaattg
    11401 atcaaatagg ctatataaac ttgctaaatc gatccgcatc tggtttgtcc agctttcttg
    11461 gataatctca aaagtcagac gcatttgtga ctgtagctgc tggatctcct gataaaaaag
    11521 ctgcaggtga tcaatggctg tcccagattc cagtggcagc tgatccaaca tctcttttgt
    11581 catcatgact tcttctggat actgtccgtt aggttgcttg ccgctcacta aactcattaa
    11641 tccttctgcc atacaaatct gtgcttcgca tagcgcagaa agttcttctc gataaatcga
    11701 taaccagcgt aaggcttcat gttctttcgg taaatagctt tgtattcggt caaacagctg
    11761 atttggttct tctaattgct ggatttgttt atggaaatag ttaatactta atcgtttgtc
    11821 atttactttt tcagcgattt ccggcaaatg atgtacttca tcgatcaaca aaaatggact
    11881 agctggaagc aatggttctt ttcgctgtgt ttcttgtact aaaaacgcat gattgacaat
    11941 caaaaaatta ctttgcctga ttttcttttg caagaaacga acaaagtctt gttcgtaaaa
    12001 tgactgattt cttgctaaaa atccaatacc tctgtgcgcg atatctgcaa agaatgaatg
    12061 gttcaaattt gttaaatgta attcatccaa atcaccagtc ttcgtttgcg tcagccaaac
    12121 taagaccgcc atttgataca aagcatattg tttttgttct ggcggttcca caagtgtgcc
    12181 tttaaaacgc tgcaaatcaa tatagtggcg atagcttttg ataattacag gttgtatggg
    12241 ctgatctagc aattgattca gcaatggaat gtctttttct atgatctgct gctgcaaaac
    12301 tagcgaaacg gtactgatga cagcgggttt ttcaggtgta gccaaataac tcaatggcag
    12361 cagataaccg attgttttac ccattcctgt agctgcttcg atcatcaaat cttttgattc
    12421 atcttttgtg aaatggtcgt agaccgcatt catcagtctg ttctgttctt ttcgatacat
    12481 cagtgtttta ccaaacattt tttcttttgc ttgttttttt cttggatatg tccgctcgcc
    12541 ataatggacg gatgtgaata gttccacttc ttttttctgc aaagctagcc catcgacgat
    12601 ttctaatgag ggatcaagtg gctctggttt ttctttcatt tcttcaatca catgataaat
    12661 gaaacgactc gtatccatac ctgtgtgtct acttaatcgc gcaatctgct ctaacgtgat
    12721 gattggcaat tttctcatcc gttcttcgat cagcaaaaga agttgacctg tcacttcggc
    12781 atcactatct gcctgatgag gattctcatg aataaatcca aggctttctg acaaatcagc
    12841 taagcgaaag cttggttccg tcggcaagaa aatttgtgca agttctactg tatcgatgcc
    12901 tggtatcttc aaactaggaa gtccgcatcg catgagttca tggttcaaaa aattataatc
    12961 aaaataaata ttatgcgcga caaatatggt gtctgccaaa agattgtaaa tcgtttgggc
    13021 gacatcttcg aaataaggcg ctttttggac gcgttgattc gtgatccctg ttaaatgctg
    13081 gatttgtttt gaaatcttcc gccctggatg aatatcgatc gaaaaacgtg aagtgatccg
    13141 acctgattca atcatgacgc agccaaattg gatgatccga tcttcttttg gattcgtccc
    13201 agtcgtttcg atatcaacga ctgcataagt tcttggtttc aaaatatctt cctcttctcc
    13261 tgcctctaat gttcttttga aattatacta caaagtgcag aaaaatactc tcatcgcttt
    13321 ttaaagaaaa tagacaaaaa cgcccagaca cgcaaatgtc tgggcgttta ttttttagta
    13381 taggttaatt aagctttagt aacgtttgtt gcttgaggtc cgcgttggcc ttcttcaaca
    13441 tcgaaagtta ctgcttggcc ttcttctaaa gttttgaatc cgtcgccttg gatagctgag
    13501 aaatgaacga atacatcgtt tccgttttct gcagtgatga atccaaatcc tttttctgag
    13561 ttaaaccatt ttactgtacc tgtttccata ataaaaatcc tccttgtgta tcaacacata
    13621 ttttgcaatt acttgaatgg tgtatatctg gaagatgttt atttgaaaca agctaccaca
    13681 gattaccgaa caaaaactac tcctatagta tatcataccg tttacaaaaa agctagagtt
    13741 tttcgacttt ttttattaaa aaaagttttc tcagcgatta cataaagtga aaaaccgaac
    13801 ttttttttaa aataaacgac atattgttca gttggtgttt ttttgctctg atgttctttt
    13861 ttaaactaaa aaaattattc tttctgacta cttatcggtt ctgtttcaac ggtcgaggct
    13921 ggggaagatt ctttagtagg tctgatgttc tcatggtatt tctgatagcc tatgacagtt
    13981 accagaagaa caaggcaaac caatacgacc aacgagatta gtttttcttt tttgctcata
    14041 tctatacctc ataaataaca ggatgatgtc catcatattt ctgagtatga gtaaaagcaa
    14101 aagctgcagc tgtagaatgt aagaaatgcc agcaactttc ataatcacag gtcggacagt
    14161 accaaaagta accaaatctt ggctgcaaag accgttcttc tgtttcagga atcgcagaat
    14221 caagatctgg tgtctgtaca taaacatttt tgtacagacg tgtgcctgta ataggaaacc
    14281 gctgtgtttc ttcagcaaaa actggctgac ttgttaaact tagggataga gacagcaaac
    14341 accataacag tctttttttc ataaagacct ccttatcgat aagtttttcc caattaaaat
    14401 catatctcaa gaacgcccgt tattcacatt ttgttcataa atgatgtttt ttgtatcata
    14461 atcgtcaaaa agaggtcgtg accacgtcac aacctctttt ttaaacggtg ttccagaagt
    14521 agcttcttcg gaaataagcc gaaatttcac aaaaatttga gaaataattt ttgtcaatct
    14581 cttcttattt cttgaagctg accacttctg tcacaacctc ttccttaaac ggtgttcaaa
    14641 agcttgcatc tgcggtaata agcccaccaa acaaaaaata tgaagagcta tttttgcttg
    14701 ctgttcttat tacttgatgc agaacagctt tttcacaacc tctcatacac ggtgtttaat
    14761 cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gtgaaactat ttttccgttt
    14821 gtttctctaa tactcaggtc aaaacactga tttcacaacc tcttttaata acgaagaatc
    14881 gctgtcagac tcttttcatc tggcgcatct ttttgatcca aaataaacac ttttccgcca
    14941 ttaatgatca catcatctgc taatgcattc aacacttgac gccgatcata ttctgtttca
    15001 ggatcttcac cgaaaccatc agctaagttt gacgtagcga taaataaatg tgacactttt
    15061 ccttctttcg cagctggaac gatatcaact aactgatcga tgaatttctt atctaagagt
    15121 ttattgtatt cttttgattc ttgagctgcg agttcacttg acagcttctt cgccccttct
    15181 tcgatatctc taaaggatag ctgcgcagga gaagcagaaa tcgcaacgtc tgcacaataa
    15241 tagggatttt tagcaatttt tttgaacatc gtctgatttt ctggtagagc aaataaataa
    15301 atcggccatt gttctggatt ttcgaaagaa tccttcaagt acgtatcaac tgcttggtaa
    15361 tagttgaccc aatcgatctc tacttcttca tcttttggat ttacgccatg gaaagttact
    15421 ccatctcggg ctccgcctcc tccattagaa gagaagttca aaccgccacc tgtcagttca
    15481 gatcccaatg cagtaacgac atcaaccggt gccccttctg gtagagatac ttcttttact
    15541 tgtttgttgc tgacttcata caatttcatg gagtcgcggt tcaatcccaa taaataataa
    15601 gaatagttga actgcccatt tttgataata gccagtaaat aaggaagatc acttacatag
    15661 tattgatcgt ctaccgggat actcaaacga tggatatagg tttggtcagc agttataatg
    15721 accgctacac tcgtagttgc actacgccaa aacgaaggat ctcctaacaa attttcaatt
    15781 ttttcttgga acggggacca gtcatgttcg gaatattttt tctcaaaacg tttctttgct
    15841 tctttcgcaa aatttttgaa tttgatctga tctttttcca catcttgatg ggcgacatgc
    15901 gtattcagca tgatcgtgac gaatggtcct ttagcgcctt ctgaagtcaa ttgtgacaat
    15961 aattctttat ccttttttgc cataaacgta cccctcctaa aaaaatcatt cctttgtttc
    16021 tatctaaagt ctaccacaac actatttttc catacaataa aacgtatcta aaaaaataaa
    16081 acggtttcta cggttttaaa tttagctatt tttttaagtt atcttcataa tttcctcaat
    16141 tatttagccc cagtcttcaa ctattcttca tgaaatgctg ataaactaag aaaaagaata
    16201 aaagaggtgg atcttatgca tttgattatg attttcagtt tattaagtat tatcagttta
    16261 tttgctttca gcgcttcccg cttattagat gcggaaacac agcctattcc tgtaaaagta
    16321 cgtaaaaacg accgctaacc ttccataacg tgcgttctta tcctaaagtt ttttcagaaa
    16381 cattgaaact ctctcccctc tctgataaaa ttttaatttg tagcgaaaca aattaattac
    16441 aaggagatcg gatatgtcca taaaaaaaac acgtctagtc ctattattgg ctagtctcat
    16501 tctttgcctt gcttcttttc taccagctgt tgctgtgcaa gctgaagata ctttcaaagt
    16561 aaatgcaaaa gcagcctttg ctgtagatgc gcaaagcggt aagattcttt atgatcaaga
    16621 tggagaaaaa accatgggga tcgcttcaat cacaaaaatc atcggtcttt acatcgtcct
    16681 tgatcaagta aaagaaggga aactatcatg ggatgataaa gtttcaattt cagattatgc
    16741 agaaaatttg agtgtcaccc cagatttatc aaatgttcct ttgcataaag aaaacaccta
    16801 caccgttaaa gaattattcg actctgcaat catccagtca gccaacgctt caatggttgc
    16861 cttggcagaa aaaatctctg gcagcgaagc aaaattcact gaacgaatga aagaacaatt
    16921 gaaagattgg ggtatcaaag atgcaacgat cgttaatgca tcaggactga ataactctta
    16981 tcttggcgaa aaccgaccag aaggtactgg agaaaacgac gaaaatcaaa tgtctgctca
    17041 agatgtggct atcgttgccc gtcatttgat cttggatttt ccagaaatac tggatgtatc
    17101 tagcactacg acacaaatgt ttggcgaaaa cacgcaatca ccagtagaaa tggtcaactg
    17161 gaactggatg ctcccaggat tcgtgaatta taaagaaggc gtggacggat taaaaactgg
    17221 tacgactgaa cttgcaggag cctgtttcgt cggtacgatc actaaaaacg atcaacgaat
    17281 catcactgtc gtattgaatg cagacggcca tgcggaaaac ccaagtgccc gtttcaatga
    17341 aacagctcgc ttaatggatt attgctacga caattggtca gaaaaagagc ttggaaaagc
    17401 caatgcaagt atccctagtc taaaaaccat tgatgtaaaa gacggaaaag aatcaacagt
    17461 gcccgttgtg cttaaaagtc ctgtaaaagt atgggtacgg aacgatatgg atactggaaa
    17521 attaacaatc acaccaactc ttgacaaaaa acaagtcact gacaatgaga tccaagcacc
    17581 tatggataaa ggaacaaaaa tcggtaccgc aacgatcacc ttggcagaag ataaattagg
    17641 ttatcttgaa gacaacaacg cgccatccac agaaatcatc acggataaaa ccgtagaaaa
    17701 agcaaatatt ttcgttattg gctggcgacg cgtcgcagaa tttttcggta acttgtttta
    17761 attgaacaaa aagaaaaaag catctttcca tgtggaagat gtttttttgc tttttctagt
    17821 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    17881 tatgaatcta accagagatc tgattttttt ggttctctat cttattgggg tattctccat
    17941 cgtttattgg cgaaaacaga aaaaggatcc ttccttgttc ttttacagca gtacatggac
    18001 gtttgcggta atcttgactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    18061 tttgattccc ttagtgtttt tcagtatctt tgccttttcc tatttttcag aaaagcgaag
    18121 gctgttgaat ggtcttttat tcaatatttt cctcattagt tttggtatct acttgtttgt
    18181 cttgctatac gaaacacaaa atatttttct tggcggactg attgccttga tcacgatccc
    18241 gttactgctt gtctttctat tcggcattta tggattgatc gtttttcttt tttggaacgg
    18301 tgtcacagtt ttacgtagag agtcgcattc attagctaat cttttaacgt tgatactagc
    18361 catttttctt acattgtttc ttgtttttga ctttttcttg ttaaaatatt taccacaatg
    18421 gataaatgct ttgtttttct gcatcccatt gatcttgatc tatctattta tcgtattcta
    18481 caactttttg actgtctcat tcttgtatca gttcaaccgc cctcgataca accaagactt
    18541 catcgttgtg ttaggcgccg ggttgatcaa tggagaaaca gtttctcctc ttcttgccaa
    18601 gcgaatcaat aaggcgattg ctttttattg ggcacaaagc cgtgcgacat taaatccgcc
    18661 tatcctatta atgtcgggtg gacagggagc agacgaaaaa gtaccagaag caatggcgat
    18721 gaaacaatat gccatggaac aaggaattcc tgaaagagat attcttgtcg aaaccaattc
    18781 gacaaccact ttggagaata tgcgctattc aaaggaaatc atggatcagc aaatgaaagg
    18841 tccctatcgc gcgatcttca gttccaacaa ttaccacatt ttcagagctg gtctctatgc
    18901 acgacaagcg aaactgaagg caaatggcat tggggcaaaa acagctttct attacttgcc
    18961 taacgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    19021 catttgcgga ttgcttttcg caggttccgc attcttatca ctgatcactt tacttttcta
    19081 aaaaaa
//
LOCUS       DADVXV010000057        18049 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.058, whole genome shotgun sequence.
ACCESSION   DADVXV010000057 DADVXV010000000
VERSION     DADVXV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.058"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(57..1793)
                     /locus_tag="KB969_001877"
     CDS             complement(57..1793)
                     /locus_tag="KB969_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBB6869846.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(1790..2494)
                     /locus_tag="KB969_001878"
     CDS             complement(1790..2494)
                     /locus_tag="KB969_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6869847.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            2625..3128
                     /locus_tag="KB969_001879"
     CDS             2625..3128
                     /locus_tag="KB969_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBB6869848.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            3088..3426
                     /locus_tag="KB969_001880"
     CDS             3088..3426
                     /locus_tag="KB969_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBB6869849.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            3447..4865
                     /gene="ffh"
                     /locus_tag="KB969_001881"
     CDS             3447..4865
                     /gene="ffh"
                     /locus_tag="KB969_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBB6869850.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            4977..5555
                     /locus_tag="KB969_001882"
     CDS             4977..5555
                     /locus_tag="KB969_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBB6869851.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            5559..6080
                     /locus_tag="KB969_001883"
     CDS             5559..6080
                     /locus_tag="KB969_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6869852.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(6159..6713)
                     /locus_tag="KB969_001884"
     CDS             complement(6159..6713)
                     /locus_tag="KB969_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6869853.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            6966..7241
                     /gene="rpsP"
                     /locus_tag="KB969_001885"
     CDS             6966..7241
                     /gene="rpsP"
                     /locus_tag="KB969_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBB6869854.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            7253..7504
                     /locus_tag="KB969_001886"
     CDS             7253..7504
                     /locus_tag="KB969_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBB6869855.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            7629..8420
                     /locus_tag="KB969_001887"
     CDS             7629..8420
                     /locus_tag="KB969_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869856.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            8590..9111
                     /gene="rimM"
                     /locus_tag="KB969_001888"
     CDS             8590..9111
                     /gene="rimM"
                     /locus_tag="KB969_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBB6869857.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            9101..9862
                     /gene="trmD"
                     /locus_tag="KB969_001889"
     CDS             9101..9862
                     /gene="trmD"
                     /locus_tag="KB969_001889"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBB6869858.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            9998..10345
                     /gene="rplS"
                     /locus_tag="KB969_001890"
     CDS             9998..10345
                     /gene="rplS"
                     /locus_tag="KB969_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBB6869859.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            10718..11380
                     /locus_tag="KB969_001891"
     CDS             10718..11380
                     /locus_tag="KB969_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869860.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            11459..14686
                     /gene="fss3"
                     /locus_tag="KB969_001892"
     CDS             11459..14686
                     /gene="fss3"
                     /locus_tag="KB969_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBB6869861.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            14800..15114
                     /locus_tag="KB969_001893"
     CDS             14800..15114
                     /locus_tag="KB969_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6869862.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            15127..15501
                     /locus_tag="KB969_001894"
     CDS             15127..15501
                     /locus_tag="KB969_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBB6869863.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            15511..15855
                     /locus_tag="KB969_001895"
     CDS             15511..15855
                     /locus_tag="KB969_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBB6869864.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            15926..17278
                     /locus_tag="KB969_001896"
     CDS             15926..17278
                     /locus_tag="KB969_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBB6869865.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            17338..>18049
                     /locus_tag="KB969_001897"
     CDS             17338..>18049
                     /locus_tag="KB969_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBB6869866.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGML"
BASE COUNT         6029 a         3231 c         3842 g         4947 t
ORIGIN      
        1 tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc tcttttttac
       61 attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc tacagtaatc
      121 gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc ggtcccgcct
      181 gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg ttcctgatcc
      241 tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc tgttgcctga
      301 tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc aattagattt
      361 ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt tccaatcaat
      421 cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat ttgctggaaa
      481 taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt tgacagctgg
      541 atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat ctcaagaaaa
      601 gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt aaaaccaatc
      661 agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc cttttgtagc
      721 ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg tccggtacct
      781 tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc tgtaagggtg
      841 atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg aatgagtttt
      901 ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac gtttaaatgt
      961 agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat caggaatacg
     1021 ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt acacgcccga
     1081 tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc ttcccattga
     1141 tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt ttttagtacg
     1201 ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat cattcctgca
     1261 agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact ctcagttctc
     1321 ggtaaaaaac cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg gccacttttt
     1381 ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt gcgcaaagcg
     1441 ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt tcgctgttca
     1501 ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat taaagtaatc
     1561 cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc tgcttggagg
     1621 ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta gctttcttgc
     1681 tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc aaaaaacaaa
     1741 ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt catcgtttgg
     1801 gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg tgttttggat
     1861 ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg ctttgtcctg
     1921 cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca cggtcttttc
     1981 gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc agatggtcgt
     2041 ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat agatattcag
     2101 gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt gctttcatac
     2161 gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca cctatttcta
     2221 ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc ggtgtttcat
     2281 ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga agcatcacat
     2341 ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg cctccatctg
     2401 tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc gttacaatag
     2461 aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa taggtttcat
     2521 tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag aaataaatgg
     2581 tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt ggaatcagtg
     2641 catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta ccagaattga
     2701 tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc ggcggattac
     2761 caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg tggaaagatc
     2821 aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa aatggcgcga
     2881 tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg aaggaaaaaa
     2941 gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata aaaaaaaatg
     3001 gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc tctgatgaag
     3061 aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg aatgaacgcg
     3121 ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat ggaattatat
     3181 tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag ccgacaagca
     3241 gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa aaaactccat
     3301 cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc atatattaca
     3361 gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca agcaatcgaa
     3421 gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa cgtctccagc
     3481 aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta aaagaaatga
     3541 tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta gtcaaagatt
     3601 ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt ttatcacctg
     3661 cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt tctgaaacag
     3721 cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt cttcaagggg
     3781 caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat gaaaatgctc
     3841 gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa ttgaaagtat
     3901 taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc ccggtagaga
     3961 tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta ttgatcgata
     4021 cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa atcaaagaat
     4081 tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa gatgccgtca
     4141 acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc actaaacttg
     4201 atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc gcaccaatca
     4261 aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca gatcgtatgg
     4321 ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg cagcaagact
     4381 acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca ttcgatttca
     4441 atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa gatctaatca
     4501 aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta gatccaaaag
     4561 atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga gcaaatcctg
     4621 atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac agtgttgttg
     4681 aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag caaatgtcca
     4741 aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc aaaggaaaac
     4801 taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag aaaaaacgga
     4861 aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg gagcttttct
     4921 atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg gcacagatga
     4981 gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact gtctggggtg
     5041 ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt aatcaagccg
     5101 gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca tatgatcgat
     5161 tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta atggaaaaca
     5221 aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc aaagcagtct
     5281 tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt tctaatggaa
     5341 aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt cctctttcag
     5401 atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc acaacaatct
     5461 atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt ttccgcaaag
     5521 aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc atattttatg
     5581 gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa tggctttttg
     5641 acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc gatacgacca
     5701 tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa gcaatttatc
     5761 cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca gatgctgagg
     5821 tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa ggaaaagata
     5881 tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa atgattgatg
     5941 aatggtatat ccagattacc cctgtattat taggggacgg gattccttta ttccaaaaag
     6001 gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa tttatcgaat
     6061 tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat gcagaaatgt
     6121 cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa tttgttagaa
     6181 aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc aacgatatta
     6241 ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg ctgcaaggtt
     6301 ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa gccgccgatc
     6361 ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact gtgtccataa
     6421 ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg gttgtattca
     6481 ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg agtccattca
     6541 gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc atcgattttt
     6601 acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc tacttttttg
     6661 ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt catacgattt
     6721 ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga gcaaataaaa
     6781 acacttactg acaaaagcta catagaagat agattactta tttttaacaa aaaagaagtc
     6841 taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga aaaaaagctt
     6901 tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg aggtggaaat
     6961 aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt ccgttttacc
     7021 gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa actgtaggta
     7081 cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta gttcttgact
     7141 ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca aaagaaggcg
     7201 ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg atatgaaaga
     7261 tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg atcaagtcaa
     7321 gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg ctcctgaaga
     7381 tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca caatcgttta
     7441 cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg ataaggaaaa
     7501 gtaaataaac gtgctgtact cgaattttcg agtgcagctt ttttgttttt tttattaatt
     7561 gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga ggagggagtg
     7621 aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta agcgcttgta
     7681 gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct gaaactgtta
     7741 ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca atggctacct
     7801 caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca aatgttccca
     7861 tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca catacaaagc
     7921 aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat gctgacgaat
     7981 tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct tctagtcaag
     8041 aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa gtggacttag
     8101 gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt gaatggcaag
     8161 aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat cccttactat
     8221 tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct gaacaatttg
     8281 gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta agctggcaag
     8341 aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg aagatggcag
     8401 tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt aactccaagt
     8461 cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct taatacctta
     8521 aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa aaagaaatgg
     8581 ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca aggtatcaaa
     8641 ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa aaaaggaacg
     8701 gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa aagtcatcgc
     8761 aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa tgatgtggaa
     8821 aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct agctgaaaat
     8881 gaattctatt accatgagat catcggtctg catgtattag aagatggaac tgagttaggt
     8941 aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca acgtccgaaa
     9001 aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga tttagaagct
     9061 ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg atgtattgac
     9121 tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta aggctgtaga
     9181 taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata acaaacatca
     9241 gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag tccagcccat
     9301 ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa gagtaattct
     9361 tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt cacaagaaga
     9421 acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc gcacattagt
     9481 gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag gtgcgatggt
     9541 catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga cttcagctca
     9601 aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc cggcagaata
     9661 taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga ttgaagaatg
     9721 gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt tggaaacact
     9781 tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag aacaagaaaa
     9841 aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg ttgataatat
     9901 gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg ctgtgagaaa
     9961 agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa tcgaagaatt
    10021 aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca ctgtgcgtgt
    10081 tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag gtgttgttat
    10141 caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt ctaacggagt
    10201 gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg aagtagttcg
    10261 ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg gaaaagctgc
    10321 tcgtatcaaa gaaatcagaa gataaacacg gaaaacttcc ttggaaatct gaaatttgtg
    10381 aaaagtcctt gtatatcaag ggctttttct tttttctcta tcacagtttt aagccatttt
    10441 tggctgtttt ggaccatttt tcaatcatat tcccttaaaa attgtcctag attgtccgac
    10501 attgactatc agtgtcgtca aaatagggca aaatttagta gtcagcttga cgacaaatat
    10561 aatacgaaaa ataccaaaac atttaccgaa tttagcaact tttgaaccca agtttctcaa
    10621 agggtcagct attagcaaaa aagacaaaac atgtactttt ctactaaaaa gttgatgtga
    10681 taggcttcta tctaaataac tattaggagt ttttatcgtg aagcaaaatg atggacgtat
    10741 catttggaaa aatcaaagtg agttaaaact gattttaaca attaatgaat tcatcgaaaa
    10801 acacggaatt acatctagcc gtcaatacca gaaaaagcta tcagaaaatc caaattctgc
    10861 accaagtatg tggttcatta acaaaaaata tggatcatgg gagaatttat tgattagtat
    10921 aggacgagaa aatactgggt atggaaaatg ggctagaatg tcagaacaag aattattgga
    10981 aatagtagaa gcctttatta agtgcgagaa gataacctct caacgaatgt acgaacaaaa
    11041 atcagtaggg aagaatattc cttcacttag taccattaaa aagatgttag gagatatacg
    11101 tccacttttt aaagaaaaaa atgatggatc tcgatttact gatttcgaac tgctgttaga
    11161 actaaaaaat gaaataatcc gattaaaact acaggatgat ttatcaatga caaagtttcg
    11221 aaaactagtt caatccccaa aactaccatc agttgataca attatgaaaa gaacgaacaa
    11281 aaattgggag gaattgatgg cagagattgg atttgattat cgaagaatca aaatttataa
    11341 gcagagaaac aacctatcca agacaaagaa aactaaatag tatcactcta aatcagacgt
    11401 tcaaaattaa aatttggacg tcttttttat tacccaaaaa cgaaaggaga tttattttat
    11461 gaaaaagcca agatttaaga attggcgttt gctcgcaaca ctgagtctat tatgccaaac
    11521 aattggtgga tcgcttggcc caacgattgc ctttgctgat gaaattactc atccacaaac
    11581 ggtaactgtg gaattggatt tggctcacca gtatgctgtc gaaggtacat ttagcgatgg
    11641 tcgtcccatg tcagaagtta ccgttccgca ctatgcagtt tacaatggtg tgaagcaaga
    11701 tattttctgt attgagccag gggtgccgat ttacaatgag ttcactcctg gttatgagaa
    11761 aaatccattg cctgatatgt cggagaaagc gaaattagtt tccgttttat ggaaggaagc
    11821 tggtacggat gtggatacac atattgtggc ccagaagatg atttggcaag aagttaatgg
    11881 ctacacgctt cactcaatta aacgttctga tggtagtgca gtaaatatcg cagccattga
    11941 gtcaaaaatc aatcaagcca ttgcggatta tcaaaagaaa ccaagcttcc ataactccac
    12001 agtgaaaacc gtgttaggtc aatcgactac tgtgacagat acgaacggct tgaatttatc
    12061 ggagtttgat gaagttgtcg agaatatcgc aaatattgat tatcgtgtga acggcaatca
    12121 actagtgatt actccaaatg ccaattcaaa agagagtggt gaattaaccc taaagaagtc
    12181 agctaataca ggaacaccgg tagcttataa aatggctggt caacaaactt tgatggcggg
    12241 ggcaattgat aagcccaata cctacacaat caaaattgat gtggaaactg agggttcttt
    12301 gaagattaaa aaagtcgata aagaaacagg aaatgttgta ccgggaaccg ttttccattt
    12361 agactttgga aaaacattac ctgcaaaaga cgtgaccacc gataaagaag gcattgcgac
    12421 attggatgag attcctcatg gcgcgaaagt aaccattact gaaaaatcag tgccagctcc
    12481 ttatacgatt gacactacac caatcaccgc aaccattaaa tctggtgaga ctatttctgt
    12541 gacttcaaaa aatactcgcg aaaaaggtca aatcattttg aataaaatgg gggtggaaac
    12601 aggaactgat ctttggaacg acaaatactc attagccgga aatacgtttg ccattcgcaa
    12661 agacagtcca accggtgaaa ttgtccaaga aatgaccacg gatgaaaaag gtcatgcgga
    12721 aacaccaaaa gagattgcca atgcgttgga attgggaacc tattatgtga ccgaaaccaa
    12781 agctagtaat ggctttgtga atacctttaa accagtaaaa gtcgaattga actatgtcaa
    12841 tcaaaccgtg gctcttgtta ccagtaacgt aaaagggcaa aaccaagaaa tcactggtga
    12901 aaccactttg acaaaagaag acaaagatac cggtaatgaa actcaaggta aagctgagtt
    12961 taaaggagct gaatatactc tctttactgc aaaagatggt caagcggtca aatggagtga
    13021 ggcttttaaa ccagagttag tgaagggaac gaaagcttct gatgaaacgg tgactttgac
    13081 tttagatgaa aagaatcaag ttgctgttaa acacttagcg attaatgagt attactggca
    13141 agaaaccaaa gcacctgaag gatatacctt ggatgaaaca aagtaccctg tttccatcaa
    13201 aaaggtggat gataacgaaa aaaatgccgt gattacccga gatgttacgg caaaagaaca
    13261 agtcattcgc tttggctttg atttctttaa atttgctgga tcagctgctg ggactgccga
    13321 aactggcttc aatgatctga cctttaaagt atcgccattg gaaggaacca gtgagattac
    13381 aggtgccgaa gatgaagcaa ttacagctta taacgagcaa ctaggttttg atggctatgg
    13441 caagtttgaa aatcttcctt atggggatta tttacttgaa gaagtagagg ctccagaagg
    13501 atttcaaaaa attacgccat tagaaatccg ttctactttt aaagaaaata aagcggatta
    13561 cactaagagt gaatacattt ttacgattac cgaaaaagga caaaaacaac caattaaaac
    13621 ggtgaccgtt ccttacgaga aactgacgaa taaagcattt tctgttagct tgaatcgttt
    13681 gatgctctat gatttacctg aagaagaaga tagcttaact tctcttggga cttggaaaga
    13741 cggaggcaaa gaattgacag accttgattc taccgagcta gttgataaat tgagctataa
    13801 cttgcatgaa atcaaagaag actggtatgt ggtagcgcaa gccattgatg tggaagcgac
    13861 aaaagctgcc caagaaaaag atgaaaaagc caaaccagtg gtaattgccg aaacaaccgc
    13921 aacgttggcg aataaagaga aaacaggaac ttggaaaatt ttgcataaat taaccgcaga
    13981 acaagttttg gataaaacca tcgtcttatt caactatgtg tatgaaaaca agaaacccta
    14041 tgaagcaggt gatgatccag tagcgaaaga tgctagcttg aacaatcaag cccaaactgt
    14101 caattgtacg gtggaacgcc atgtttccat ccaaacaaaa gcccacctag aagatggttc
    14161 gcaaaccttt actcatgggg atgtggtgga tatgttcgat gatgtgtcga ttacccatga
    14221 tgtactggat ggctcaaaag aagcttttga aacaattctg tatgcattac ttccggataa
    14281 tacgaccaaa gaaatttgga aatctggcaa aattgattat gaagtgaatg acaaagaatt
    14341 cactaaaacc gtacttgcgg aaaaagtgga cacaagtaaa tatccagaag gtacaagttt
    14401 taccttcaaa gaaattaact atggcaaaga cggaaacatc aatgggaaac acaatgagga
    14461 tctaaaagaa aaaactcaaa ctttaacacc taaaaaagtt ccgacaacac caagtgcacc
    14521 agaacaaccg gaaataccaa ctgttccaag tgactctcaa gaatctagtc ctacagtaaa
    14581 gacattccca caaacagggg agaaaaattc taatgttctg ctgtttattg ggtttacctt
    14641 gatctttgcg actgctgggt attatttctg gaatcgccga aactaaggtg atgtgatgaa
    14701 acaactaaat aggaaaaacc aacgtgcgcg accgcctcct aaaaaaagtg gtcgcgctat
    14761 ttttgtatcc aaaactaaaa atgaaaagag gaaaagaaga tggaattgaa atttgttgtg
    14821 ccagatatgg ccgaaacctt tggaaagata aggtatgccg gcgaaggcga agttttaact
    14881 gaaggatatg ggcggaatac tacagtaatt ggtcgtagtt atcatttgta ttccagtaag
    14941 caacgagccg atgatattga agtggtggta gctgcggaag ccggcgaaaa ggattttgat
    15001 caagatcaac cactaaaagc cgtgaatccc catttggttg ccaaaggcta tgagattgag
    15061 aatcgtgggt ttaccgacta cgtgttgtat gtcgatgatt tagtgaaagc ataggaggaa
    15121 aagaagatga gattaacaga aggtattgtt gtagattcag gactaacgtt tgggaaatta
    15181 cgattttccg cattacgccg agaagtacgg aagcaaaatg aggatggaac ggttagtaac
    15241 gaggtaaaag aacggactta taatttgaaa tcctctgcgc aaggtcgaat gatccaagtt
    15301 agtatcccag caaatgtacc cttacgcgag tttgcctatg acgcagaggt agagttggtc
    15361 aatccaatca tggatacggt cgccaattat gttttccgag aaggaactac tgtcaattgg
    15421 ttcattaagg ccgatgattt agtcttgaaa cgacaaccag atcagggaaa ttctacaaac
    15481 caaaatgaag gaaagaaata ggtgaagcgt atggaaatta atgttgaaca tattttagat
    15541 tgtctcgatc aatatggaaa aggtgagcta acggaggaac aactcactaa agcattaacc
    15601 tatgatgaaa aaatgtttct gattatgcat caagggttac tggaagtagg taacgatgtc
    15661 gaagaagatt ttgatgtact gaattggtta ggggaagaag agtccttctt tatggttatc
    15721 gaagtaaatg aaagtctatg tcgagaagcc gaaaccgtat tggaagaaat tggtgtggaa
    15781 atgccggatg ccattgaagt ttttttaaag caactagtgg aaacgaaaca actccctata
    15841 gcagtaaatg actagcataa ctgcttgaaa ttggatcaat gaaatcctat gaagcttttt
    15901 tcgattggag gtggaaacca taaaaatgta caaagggcat cgtatacggg caggagatca
    15961 gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg gttggatgag
    16021 cgtcttttat tttcaagagc ttagacaatt tgatatttct aagctatcac tttctactat
    16081 agaaatcgtt cgttctataa aagatttaat ctatttgcta ggaagtctcg ttctttcagg
    16141 aagcacgatg ttgctttata tacacttttt tcaggatcat tggcgcagtt tgtggcatcg
    16201 acaaaagcta gcccggatga ttctagaaaa tcattggtac gaagtaaaac aaactcagag
    16261 tgaaggattt ttcaaagacc tcaatagtag tcgaaccaaa gagacaatca gttacttccc
    16321 caaaatctat taccgtatga aggatggttt actttctatt cgcgttcaaa tttcactggg
    16381 aaaatatcaa gatcagcttt taaagctgga aaagaagtta gaaagtggtc tatattgtga
    16441 actagtagaa aaggaactca aagactccta tgtggagtac actttactgt atgatataat
    16501 tgccaatcga attgggatag acgaagtagt ggcagaaagt ggggctttgc gattgatgaa
    16561 aaatcaagta tgggcttatg attctttacc tcatatgtta atcgctggcg gcacaggtgg
    16621 tgggaagact tactttttac tcactatcat cgaggcttta ttaaaatctg atgccgagct
    16681 ttttgttctt gatcccaaaa atgcggactt agccgattta ggtacggtaa tgcctcatgt
    16741 ctattcccaa aaggaggaaa tttctgcttg tgtggaagat ttctatgagc gcatgatgac
    16801 tcgtagcaag gcaatgaaag aaatgcccaa ctacaaaaca ggagagaatt atgcgtttct
    16861 tggacttcca ccaaactttt taatctttga tgaatacgtg gtttatatgg aaatgttaac
    16921 gacgaaggaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt taggtcgtca
    16981 atctggtttc tttctgattc tagcttgtca aagaccggat gcgaaatatt taggagacgg
    17041 gattcgcgat caatttaatt tccgggtggc tttgggtcgt atgagtgaac tgggatattc
    17101 catgatgttt ggcgaggttg ataaaaaatt ctttatgaag cgtatcaaag gtcgaggcta
    17161 tgtagatacg ggagggagtg tgattagtga gttttatacg ccacttgtac caaaaggata
    17221 tgatttctta agggaaatta gcgacattgg tggattaaac gttaatacgg aaggataaaa
    17281 taatagtatg tagcctagga gtgtcaagaa tcctgggctt tttttacgag gtgatttatg
    17341 acatttttag atttattcgc tgggattggt ggcttttgct taggtatgga acaagcgggt
    17401 caccagtgta tcggcttttg tgaaattgat gattttgctc gccagagtta taaggcaatc
    17461 catgatacaa gtaaggaggt ggaaatgcat gacatcacaa gtgtatcaga cgagtttatt
    17521 caatctctcg gaccagtgga tatcctttgc ggtggatttc cgtgccaagc tttttcaatt
    17581 gcgggaaagc ggcaaggatt ttccgatact cgaggtactt tattctttga aatcgctcgg
    17641 ttcgccgcta ttctccaacc taagttttta ttccttgaga acgtccgggg attactcaat
    17701 cacgaaggag gggctacgtt cgagacgatc ctccgaacgc tggatggatt ggggtatgat
    17761 gtggaatggc aagtgcttaa ctcaaaggcc tacgttcccc aaaaccgtga gcggatcttc
    17821 cttatcggac attctcgaga cgcatgtacc gaacaagtat ttcctatcat tggatcgtct
    17881 ccaacatctg atcaaaacat cagaaactta ttaaatatca acccttccaa tcgaggaatg
    17941 gggggacaag tctatgggtc agatgacgta gcgcctacct tgaccggtga tgaaggaatc
    18001 aaaatcgcat tgccggtaga tgatggaatt tctgtagcgg gtatgttac
//
LOCUS       DADVXV010000058        16945 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.059, whole genome shotgun sequence.
ACCESSION   DADVXV010000058 DADVXV010000000
VERSION     DADVXV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.059"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(276..890)
                     /locus_tag="KB969_001898"
     CDS             complement(276..890)
                     /locus_tag="KB969_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6869867.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1496..1873)
                     /locus_tag="KB969_001899"
     CDS             complement(1496..1873)
                     /locus_tag="KB969_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869868.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2173..3054)
                     /gene="galU"
                     /locus_tag="KB969_001900"
     CDS             complement(2173..3054)
                     /gene="galU"
                     /locus_tag="KB969_001900"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBB6869869.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3097..4116)
                     /locus_tag="KB969_001901"
     CDS             complement(3097..4116)
                     /locus_tag="KB969_001901"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBB6869870.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(4749..5753)
                     /locus_tag="KB969_001902"
     CDS             complement(4749..5753)
                     /locus_tag="KB969_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6869871.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(5766..6815)
                     /locus_tag="KB969_001903"
     CDS             complement(5766..6815)
                     /locus_tag="KB969_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6869872.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(6832..7653)
                     /locus_tag="KB969_001904"
     CDS             complement(6832..7653)
                     /locus_tag="KB969_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6869873.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7640..8419)
                     /locus_tag="KB969_001905"
     CDS             complement(7640..8419)
                     /locus_tag="KB969_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6869874.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8436..8906)
                     /locus_tag="KB969_001906"
     CDS             complement(8436..8906)
                     /locus_tag="KB969_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6869875.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(8918..9337)
                     /locus_tag="KB969_001907"
     CDS             complement(8918..9337)
                     /locus_tag="KB969_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBB6869876.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(9418..12195)
                     /locus_tag="KB969_001908"
     CDS             complement(9418..12195)
                     /locus_tag="KB969_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6869877.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            12386..12610
                     /locus_tag="KB969_001909"
     CDS             12386..12610
                     /locus_tag="KB969_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869878.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            13389..15104
                     /locus_tag="KB969_001910"
     CDS             13389..15104
                     /locus_tag="KB969_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869879.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            15107..16870
                     /locus_tag="KB969_001911"
     CDS             15107..16870
                     /locus_tag="KB969_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869880.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
BASE COUNT         4998 a         3483 c         2881 g         5583 t
ORIGIN      
        1 catatggatt ctttcttgtc tctttttcca ctacttttta tttttctgac actacatatt
       61 cttataactc atttctcata actgtgaaac aacttataaa aataacaaac tttaaacaaa
      121 acaagcttaa aatcaaagat gatccatctt aaaataacta aaacaaaaaa agtagtcgtt
      181 gttaatcctc attaataatc gttttctttt tttcaaacgc tccattttta tgtggaacat
      241 tattttttta aggaactttg tcaacatgtg gataactatt ttccacttgt gtcctggact
      301 agctgttttg ctgtaaaata caaaacttgc tgcagcaaaa agatcgttgc aagagaggct
      361 gttccgcaga tcgctggatc tagatttggc aaagtcaaga ctgcatcatg taaattggcg
      421 tggttgtcca aaaccaaatc agcaaattca aataatcgca aaccactgct atgttgcgat
      481 ttgatacttc gtgacaaatc aaatccagta acaatgatta atggatgacc attttctttg
      541 atccactgag ctagttcgat gattgccggg tttcttcctt cattcgaaag aagaagaaaa
      601 atgtcttctg atttgacaga aagctgatca ataattgcct gtcctgcacc ttctagcgtt
      661 tcatagacac ctccggctgg attttcaatc aatatacttg gtacaagatc cggggtttga
      721 tcccaaaatt caaatgctac accacttagt gtgcggctag catatatctg caatctacca
      781 ccttgattaa tttgtttcgc gatccaagtg ccagcttgaa gcatcagcgg ctcttctatc
      841 cttaatttct cttccaattg gtgataatag tcaaaataac ataaactcat ttatctctcc
      901 cgcctagcta tacttgacat gaatagaaac agctgcctaa tctaaggaag tacataaaaa
      961 aacagtagtt agacagtaac acatgtggtc tttgctgttt caaacacaaa aaaggcattg
     1021 aacgaatacg cccaatacct tgacatagca aataaaacaa cgtgcagacc atggaaaata
     1081 tctacatagg ggtagaattt tcaccctaga ttaggtacaa taaattaggt cgatgcactg
     1141 cattgactat ggcaaaatga tcggtcaggg tgtatgtgtg tgactggtca ttccctgatt
     1201 cttagcgcca actaagggtc agggagcctt tttttattca gctgtttcta tctgaattta
     1261 ttgtaagtaa tctcttatcc aagtgcaagc aagaaaatac aaaaaaacat tggtatgatt
     1321 tatatatata taaataacat aaaaaaagga atggcttatc ccgatacaac aagcattcct
     1381 ttaaaaaaga ttcttttata taagtgaaaa aagctttttt ccaccaatta aataaatctc
     1441 tcatctcaat agtttatcca ttattttatc tttttttgcg tatacctact aaatattacc
     1501 gtcttcttct cgttcttcta ctttgttcga gagaatctgt actagaaaaa gtagttgtat
     1561 gtctaccttt tctgcctatc cgagactttc ttttcatata tgggatataa atgattagat
     1621 acagtacagc aaaaaataaa gcaaatacgc aagcttccca actacctaac gccaattcaa
     1681 ccatcaaggt agcaacccca acggatgctg cataccagat aaaaatcaga aacgtttctt
     1741 tttttctgac catgcgaaac atgataaata gactaataag caatagtggc aacacaaata
     1801 tccaattgct tccttccatc agccacttga gtatatcaag cagcgactgt gcaacagcga
     1861 ctaattttcc catagtgaac acacaccttt ttttataatt aaaaaattcg cctttttatt
     1921 ctactatgaa tcttctggct tggctttcat ttctcttatg taatcatttt cttttataca
     1981 acttaaaaaa aaattaaacc attagcataa tattttctga atctattcac gaaagtcttt
     2041 ttctatcttt cgttttccac gactcaactg atctagagtc aaaaaactaa aacgacagtt
     2101 gcgcaaatga cgcacaagct gccgctttaa taacaaatag cctttcattc tcagcaggcc
     2161 acttatttcc agttaacttt ctgttcttag ctttttactc aactggataa tatatgcact
     2221 taatgaagtc ccaatttccg aatgttgaag tccatattca atatttgtct tcatatatcc
     2281 taacttatcg cctacgtcgt atctttttcc tttaaactct ctcgcataga ccgcctctgt
     2341 ctggttaaga gtctgaagtg catccgttag ctgtatctcg tttcctgctc ctggttcttg
     2401 agtttctaat atctcaaata ttttaggagt cagtagataa cgtccgataa tggctaaatt
     2461 acttggtgct tttcccattt caggtttttc tacaaaccct tttactctgc aacgaccctt
     2521 ttcgctatct gttttaggat caataattcc gtatttagat gtttcatttt ctggtacacg
     2581 catgacggca acagcggaag cttgtgtttc ttcataatcc atcatcaatt gttgagtcaa
     2641 tgggatatca tctttcatca aatcatcccc cagcatgacg acaaacggtt catttcctat
     2701 aaatgctttt gcttgaagca cggcatcccc cagtcctctt ggatgagatt gacggatgaa
     2761 gtgaagattg acttgagtcg tttcttcaac taaagcgagt aattctgttt tttccttttc
     2821 ccgcaaattg ttttccaatt cgatatttgc atcaaagtga tcttcaatgg gtcttttttc
     2881 ttttcccgtt acgatcaaga tgtcttcgat tcccgaatcc aatgcttctt ccacaataaa
     2941 ctggatcgtt ggtttatcca cgattggaag catttctttt gccatggctt ttgttgccgg
     3001 caaaaaacgt gttcctagcc cagcggcagg aatgactgct tttttgacct tcacttgctg
     3061 ttcctcctaa acgacgatta actattgatc atctatttaa cgaagagaaa attcattctc
     3121 catttttccg tcacgtaaca tgatttcttt tgctgctttt ttgatatctt ctccattata
     3181 caaaacatta tagattgttt gagtaattgg catctcaaca cctagctgtt gagctagctc
     3241 tactgctgct tttgtcgttg ccacaccctc aacgaccatt cccatgtttt ctagaacttc
     3301 ttccagctta tgtccctgtc ctaacaagtt accggcacgc caattgcgag aatgaacact
     3361 tgtacaagta acgatcaagt cccccacacc actcaaaccg ataaatgtca gaggattggc
     3421 acccatcgcg acaccaagac ggctgatttc tgccaatcct cgagtcatga ttgctgcttt
     3481 tgcatcatct ccgaatccta atccatggat agcgccggca ccaattgcaa tgatattttt
     3541 cagtgctgca ccagtttcta cgccaatcac atcattattt gtataaatcc tgaaataatc
     3601 attcatgaac agtttttgta cataggctgc tgctttttga tcaatacttg cagctgtaat
     3661 tgttgtgata tcatgtactg ccacttcctc agcatggcta ggaccagata atacaacaat
     3721 tgcctgtctt ttttcttctg gaatttcttc agccaaaact tctgagattc gtttatgcgt
     3781 atcttgttct agtcctttac ttgcatgtat aatgattggc ttagtattca ttttaccaat
     3841 aagttcctgt gcgactgaac gaatcgcttt tgttggaaca acaaataaaa tagcatctgc
     3901 gttatccact gcttctgcca attctttata tccgataatc gattctggga tcgtcaaatc
     3961 aggtaaaaaa tgctgatttg tatgatactt attgatttca tcaatctgtt caggtacatt
     4021 tccccaaata cggacatcat gcccgttttc tgccaatgtt tgtgctaaag cagtgcccca
     4081 agatccagga ccaagaactg cgattttttg tttcatggat attcctccaa ataaataatt
     4141 gataatttcc attatagtat acatttctta aagttgggac taatttccat tgtttttaag
     4201 tgtttgttta cttcttttat cgtttttact tgaaataatc aatgatatgt tacaatagtc
     4261 tacattttat ttttacactc gttatgcttt gcttgttcct aagaggaagc agttttgaca
     4321 atgttactac cagcattact attaggaggt taggaaactt ctcctagtga gtattgattt
     4381 aaaatacata agagacagat tgaacatttc taaatctgtc aggtcctgca acggacagat
     4441 tgtctctgtt gacggttgac ataggaactt ttgttttagt caacattctg gatacaaaac
     4501 gctatgtaaa ctggcgcaac tcgttgtact tggactttta ctacggatcc atgcaacaac
     4561 taaatagtac tattgcataa caaaaaatgg ttggcaccca catgtcccat taaacagatt
     4621 ataagttgaa ctgtagataa tgcaaaaaat gtgttttata acgtaattga tgccaatatt
     4681 ttaaaaaaat aaagggagca gttatcgctg ctctctttat tttttatatt ctttttatcc
     4741 agtctatcct aataatcaaa ctgacgatag tagcggcgta tctctaatgg atggcagttc
     4801 aactgctcca catgagcatc gatgcgttgt gtcactacat gcatcaataa gaaagacaaa
     4861 acacgtccgc gatatttttc actgatacct tctactggat agtcttttgt gtctatcaat
     4921 gtataattgc tgcaaatttt tggcaaaagt ttagccacac gttcagataa cactctctgt
     4981 tcatcttcgc ctaaaaataa tgtgactggg gttgtttctt ctacgatctc taacgtcccg
     5041 tgaagaaact cggcagcatg gatagatttc gatggaagcc agctttgttc ttcccagtaa
     5101 cacatggcat atgaataaac agctccccat tgattccctg ctccaataaa ataatgcata
     5161 ctatcacgtc gatgtttttc tgcaaatgat aagccaaatg catctgcttt tttctctgct
     5221 tccactaacc ctgttggtaa ataacgttcg agctgttcat agtattctga ataagcttcg
     5281 aattctccat tcaaatacat caatcgatct gctgccataa aaaatttgat ttgttctgtt
     5341 ccaggagctg gataagtgac cacaaaatcg catagctgag acaacttact gttcgcttta
     5401 tcgataaatc caatcagtgt cgctcctact ttcttgattt gttctactgc tttcactact
     5461 tcttgagttg taccggtaac agaggacaaa ataacgatag aatcttttgt taatcttttg
     5521 tttccagtag tgtaatattc tgcagcatgc tgtacaaaga caggcaagtt gcttttccca
     5581 ttcatataag tgacagcttg catcgaggaa gcatacgttc caccgattcc tagataatag
     5641 acagcgtcaa atttttccgc ataaagttta tcgatgattt cttctacttg cggacgtaaa
     5701 gctagtgcgc cttttattgc tttgatttgt tcttcttcat tgaatttcag catgatttcc
     5761 acctcttata atttactttt caagactgta tcaaagtctt caaaaatctt tttgttcaag
     5821 tcaatacctt tagctactgc ggttttataa gcgaatagtt gaaacggaac gacaagcgct
     5881 aatacagaca gatattcatc acattctatt gctaatccaa gtgttttctc gtttcttgct
     5941 ttttttgtgg taatggtgag agtctctcca acgtaccgac tcatatatct ttgcaacttt
     6001 tgcgaacgtt ccttatttac actttcccct tcaataaaga atagcaaatg cgaagcatct
     6061 gcctccaggt atgggccgtg catataagct tctaactcaa atccttgtga cggaacgcgg
     6121 attgtttcag tcaatttcgt ctctgcttct ttagctgttc cccagtttgg accatatcca
     6181 atggtgacga aacgctgtgc taaacgaaat aaactttgat atccatcaaa aaattcttcc
     6241 gttttttgaa taatcgctgg taaatggttg attattttgc gcaactgttg catgtagtct
     6301 tgttctattt ttttgctgat tttattttta cttattccaa ttcctatccc taagagtagt
     6361 aactgtaaaa cagtcgcaga atagcctttt gtaacgaagc ctactgattc taccccggca
     6421 cctaaatcaa taatttgtgc agcttctaaa gcaagtggac tttgcacgtc atttgtgata
     6481 gcaacaacag gtaacccttg tttttgtatc atttttactg cttcaacagt agaagcactt
     6541 ttcccgcttt gtgacacagc aatcacagta tcgattgaag gagaaagttt tccataattg
     6601 aaaaaataaa aaggttcttg aatatcgaca gtaagatcac cataagattc caatgctggc
     6661 ttcgctgcta aacaagcgtt ataagatgaa cccgttgcta agatcagtaa attcactgtt
     6721 tttttcatat gttctcttgt cgaaaaatca ttctttttca agatcgtact tagtacttcc
     6781 ttttcttcat agatataatc ttgcatcgta aacattttct ctgctccttt tttaaaaaat
     6841 ccctatccac gaaccaaaaa ttccaaagaa agctagtccg atcaagatcg ttaatggttt
     6901 cacttctttc ttcaatagat aaaacactat gccaaatgct ccaagacata agatatttgg
     6961 aacgatatca tcaaaaatac tttgaacagt cacagcattt tctcctgaac cgatttttaa
     7021 aggaatattg atggtgatca tcgtggcagt cattgctcca acgaccatca gtccaataat
     7081 agacgcgcct aatgtcaaac tttccatcat accgtttgcc tggatctttt tcaaaaaacc
     7141 cgttcctaag cgatatcccc aacctgttgc tagatagcga aacagaatgt gcggaatatt
     7201 gaaaatcaaa atgaacaaga tagggcctaa aatatttcct tgcatggcta aagaggtacc
     7261 cacacctgtg gcaatcaatc gcaaagttcc ccaaaagaaa gaatctccta accctgcaag
     7321 aggtcccatc aaagatgttt tgatactatc gatcgcagtc acatcaaatt caggatcatc
     7381 cttattttct tcctccattg cagccgtgat tcctaaaatc agtgtaacga tatgtggggt
     7441 cgtgttaaaa aactctagat gccgtttcaa agctgctgcc atttcttctt tcgactgata
     7501 taactttttc aaaatcggaa tcattgcata aacataagcc atattcatct gacgttcata
     7561 attccaagaa aactccattt gaaaagaacg ccaaaatacg tgatttagct cttttttcgt
     7621 tattttgctg tttttgatct cagaattctt catcttcttc tacctcccct gcagttgttt
     7681 gaagtggtag ttgacggaca ttcataatat tgactaccac aactgctaaa atcgcaccaa
     7741 aaatagctac tccggtcaca ggaatctcta agtaagaagc tatagcaaaa cctaagaaaa
     7801 aatatggtgc aacttgtttg ttgatcagca aacgagcaag catcgcaaaa ccaagagctg
     7861 gaatcaaccc tgtagctact gacaacccct tttgaacgaa gtcaggaatc atatttaata
     7921 gatttccgat cgtattgctt cccaccatat aagaaaccat taccacaaca ccaagcatca
     7981 aggaaagacc gataccggca agcaagtgca tatgctcgac tcctttataa tttccttctt
     8041 ctgcataatt gtctgcttta tggttcataa ttggaatcaa aagccctaag taaatatttt
     8101 tcaatatcaa tgtcaacgta gcaatcggca aacctagtaa aagcgcggtt tctgtaccgg
     8161 ctccagctgt aatagcaaaa gccgtcccta aaatcccacc ggtcacaaca tcaggtggaa
     8221 tcgaagcacc tactgagaac gatccgataa atgctaactc taaagttgcg cccataatga
     8281 tcccagtttt tacatcacct aacacgattc ctgtaaacag ccccgtcaca atcggacgag
     8341 aaagcaacga tgtccctagt gcatattctg attgtgcgac aaatgcaaca attcctaata
     8401 agactgcttg tacaatcatt gaggttcttc ctttcttaca aaacttctct tacatccact
     8461 tttttatctg ctggtacttg acggatttct acttctattt gtttgtcaat taatcgtttc
     8521 aagcgttcct cctcttctgg taaaatattt accgcttttc cgatgctgcg agtaccaggt
     8581 tttgccttga tccctcctaa gttgatggtt ttgatttctg gatacgcttc tgccagctta
     8641 tatgcatcct cgatcgattc cactacgatg aataacttat atttatctgt caccccgctt
     8701 ttcaacgcgg caatcgagtc atcaattgat ttgatcacta gtttgactcc ttgtggcttg
     8761 gctaatttga tcgttgtctt tcgtatctca ttcgtaggta catcatcatt agcaatcaaa
     8821 atacagtctg cgcctattgt ttgtgtccat gaaaaagcta cttgtccgtg taataaccga
     8881 tggtcgactc ttgtcaatac aatcattttt cttcctccta aaattcgtct tcttctattt
     8941 tctgattgag ccgctcgtta caaaactgga tcattttttt tgaatcagtt agcacctgct
     9001 ggatcaaaac agttgtctct acttcagcgt ccaaccgaga tactagctca atcaatagtg
     9061 gcaaattcaa tccggcaacg agatagacat gatcccgatt gatatattgt aagaattcgt
     9121 tgttgacact tccgccaaaa agatccgtca gaacaatgat ttctttatct ttgtacctca
     9181 taaaaagctg ccttactgtt tccgctaaat caaaattctc atcagtatag caatcgaata
     9241 cagtaataga atgatttttc ccatagatca gctctaatga atctaatatc cctgaagcaa
     9301 attttccatg ggaagctaag ataatttctc tatccacttt ttcatctcct cttttcactt
     9361 acacatacta aaaaagcaag ttgcatgcca aaattagtgg caacaacttg cttatgttca
     9421 aaattcttct tctatcgaga gaaactctgt atcttcactc aaaatatcat agatataggc
     9481 aatctcagaa ttggggatca tgacactata atgctcttca atgacactaa acgcagattt
     9541 aatagcagat aacccttctt tttgacactg cttccatttc tctaatcctt gataggtttc
     9601 gattggcatt tgtcggatca atcgttcaat gagacagctc acatggacat acaacgctaa
     9661 ttttttggga ttgctgatgc ttcgattcaa ctgcacctct aattctctca taaaatgatc
     9721 gatttctccc atcaccttct ctgtatctag aatagtcacg gaatccagta ctttttccaa
     9781 tgaaaaatta cgaatgatgc gctgattgaa tatttccttc tctgaagcat tcatagtagt
     9841 gtccaaccat tcagctagta cagacatctt ttcccccgag atgaggtctt ctaatgaaag
     9901 atagtcgata ttggtgatat caggatctgt ggtgccaatc attcctacga cttcgtatat
     9961 ggaaaataat gggtcactgt ttttcttatc ttttaattgc tgatattcat atgggatgat
    10021 tttcaactga caagccgtag gtaagctttt ttctagcagt tcacttaagt ggaccgccgt
    10081 accgattcca gtgaagcaag tagtaatgag tgctttgggt ttgttttcct ctggatagag
    10141 cagtcgccat tctggctgga tctgtcgaac agtctcttct gctatctctt ctaatgatac
    10201 atttttttgc aggcattccc ctactgtgat tgctaaaggt gtcgtcacat tattcaaaat
    10261 caaaagcggt acggataact gttttttaaa aaactgatgg atttctttca gagatcccat
    10321 gtctactaat atgatcaatc catttgaaac atcgctgttt tcgcaataat caaggatttc
    10381 tgaagcaatc tgctgtggtg tgacatctag tggcatatca aatgattcaa atagatcctc
    10441 ttgtaataaa cgatttacta catttgccat actgctagca gttgcataac cgtgagcagc
    10501 aatcatcgct tttggcagtc gtttttcttt tgaccatttc gcttttttta gatagatcgt
    10561 cagtaaaatc cgatccatac ttgtgtcttc aatatctaat ttgatcttac ttaattccag
    10621 aattcgttgg acatagtgat aactagatgg ataagactga gaaacttgtt gttctaattc
    10681 tttgattagt tggataatat catgttcttc cggtaaccat ttgatagtgc ttcgctgata
    10741 gagatagtaa ctcaaggcat agacactgtt tccatcgaat ttgatttgat aggcagtttc
    10801 catttgtcga aaggtctctc ggatagattg tgtccaataa accagcagct cgtgtttttc
    10861 ttgtctactg gtctcaaaca gcaaaaaatc aaataattga atcacttctt gctttaattt
    10921 tccttcgcaa gaatatagca gacagttatt tttcttgaaa tcaattagga tttgctcaaa
    10981 acttttaacg attcgctgct gttcgggctg ttgcttctcc attaattgct ctaaggtctg
    11041 gtcttgcgta atatagattc cttgctgtgc tgtattttta gtaataggct gcgcaagtag
    11101 ttctttttgc aaatgatgga tcgtgacatg gatttcaggc tgttcacgct gttcagcata
    11161 tgcttttgct gctgaaactt tgacgatatt tttcagctct cctatgtttc cggataattt
    11221 ctgacttgtt aaaagtgaca aagctggtcc actgactgac aaagggctcc ccatttttct
    11281 ttgttcttcg agaaaaaaag agtaaatcag ttctagccgt tcattacgac tacgctgatt
    11341 aagtgcaggt agttcgattc ggataggtat tcttcgaatg aaagttgtta agaaatgact
    11401 agtaatctct tcagtcgtag caaaaaagag acgtgttttg atccggcgtg acaaattagg
    11461 ttctcccata cgataaatca caccttgatc aagataggtg aacagttttt cctgaccttc
    11521 tggtgttaag cgatgtacct cgtctaaaaa caagatccca ccatctgctg cttcaaaagc
    11581 ccctttttta ttttcttctg caccagtgta cgctccctta acatgtccaa acaaattgct
    11641 agtcaaaagt tcaggattat ctgcatattg tgcacaatta aaagtgatga atggtgcaga
    11701 atcttctagc agatcatgaa gcagacaata ctgatagacc aaattaacta aataactttt
    11761 acctgtgcca ctttcgcctg taatcaaaag tggtaatccg ccatctggat agtaaagagc
    11821 tgttttgatt tgttcgatac tttctttcaa actggcgtcg tatccgatca taaaagagaa
    11881 taagtctttt ggttgcgcga aaaaaggctg ttcctctttg agatcatcga tagaaaaata
    11941 aaaattcgtg cgtaacttaa aaaattgttt ttcaaaagct tctttgtgga aataaatcac
    12001 tggtcgagaa ttgattttga ctagtagttg ctcatcattt aactggttca aataatgact
    12061 gactgtgttt ctttttaccc caaaatgatc agctaacctt tgtgctgtaa agacctcgtt
    12121 catatgttct aaatcgaaaa aggctgtctg gttctctaag taacataaaa tttccttctt
    12181 caacaactta ttcacccctc ctccatcata gaaaacggat tcattttgtc aataaaatct
    12241 ttaataaaga attgaaaaat atatcttatt atagacagca gcctacttat cccttataat
    12301 ttttattcta aaaaacgtac agttccttcc agtttttata ctggaatttc aacatatgaa
    12361 agaataagga ggctatgact attcaatgaa atcggataaa tataaaaaca ggaaacatac
    12421 ttcctggaaa acttttcgag aaatcatcgg atcttatctc gctgtagttg tatttttgcc
    12481 tttgctttat atggctatga cagaacaaac tcgttttatt ggcgtagata cgcaatatat
    12541 agccgaaaca ggatttttat tcatctttat cttgattttt gcgttctata aatccttcca
    12601 tacaaaataa gattcacaga tttcaacttt cctgtctgtt tttagctatt acaaatcctt
    12661 atatgtggta taacaacaat ttattggcat aatgaggaaa aacgagttat gatgctttca
    12721 gagagtaaag aggtactgtt gtcaccatcc tttttattga ttacgtacac cactcttagt
    12781 tttttcccat tgattacgaa aacaaggtag aaacattgat gttcctacct tgttttcttt
    12841 ttttattttc agatcaaaat ctcaagtggc ttttgacttg atgtcgggag gttgtcttcg
    12901 ttccatcaaa cctgatagaa tctgcgccaa accatagttt tctccactat tatttattcc
    12961 tctaagatag tacccacaat aaacgaataa atatttttct cattttcata ctccttcttt
    13021 gaaaatcaat tagatttctc tcaacccact tttttacaaa aattacgtag caaaaaagat
    13081 tgcaagaaca aattaaaaaa gaagtaaata gagtttcatc tataaacatt tacttgatat
    13141 attttttatg cagaattcat ttatagaaaa attaagtaaa atagacgttc ctatgaatga
    13201 agagactggc atgttttctc attttctttt ttttaaaaaa aatagtctat tcaatttcta
    13261 aagcttcttc ataataaaac tttcatttat gaaaaggctt gttctctttt cattctaaat
    13321 ttcctaagct acaatgtggt agtacttgtt ttttcaattg tggacaaata aataatagga
    13381 ggaatcatat gattcagtta ttacgttatg caaaagacta tcgtaagcaa atcattttgg
    13441 gcccgttctt caaatttctt gaagctgtct tcgaacttgt cctgccttta atgatggctt
    13501 ccttgatcga taatggacta aaaatgaatg accgaggaaa aatcattgaa atgggcttat
    13561 ggatggtcgc tatgtctgtg attggtctga tttgtgctat catttgccaa tactatgctt
    13621 cagtagcttc acaaggattt ggtacagagt tacgtaatca gctaatcaaa aaaatcaata
    13681 ctttctctca caacgagttg aatcattttg gaacagatac cttgatcacc cgaatgacaa
    13741 acgacatcaa tcagcttcag ctagctttag caatggtcat tcgtttattg atcagagcac
    13801 cgtttttaag tatcgggtca gtggtcatgg cttttgtgat cgactgggaa gtaggtctgt
    13861 ttttcttagc attattgcct attttctcaa tcattttatt ttttatcatc aaaaaaaccg
    13921 ttcctctcta ccaaaaagtg caagaaaaac tagatcagct caatgaacac gttagtcaga
    13981 atcttagcgg tgttcgtgtc atccgcgcat ttgcgcagac aaaaaaagaa acagagaagt
    14041 tcgataaaag cacaaatgat ctagcgaaca attatttacg tgtttccaat atctctgccc
    14101 tattatcacc tgctacaacc ttgatcatga atgtcgggat catctgtttg ctgacagttg
    14161 gcgggatcaa agtaaatatt ggtagcttgc aacaaggaca agttcttgct ttgatcaatt
    14221 atatgaatca aatgcttttg gcactgatcg ttgtttcaaa cctcgtcgtg atcttcacac
    14281 gtgccgaagc ttcaggaaat cgggtgaaag aggtgctaga cacagaaaat tcgattcttg
    14341 aagctgaggt cagtactact cccgattttt cttctgaagc aattatcgct tttgaccatg
    14401 ttgacttccg ttatactcct gattctggtc tttctctcca aaatattaca tttcagctga
    14461 agcgaaatac agtccttgga atcattggtc caaccggaag cgggaaaacg actttgacac
    14521 aattgattcc gcgtttctat gatgtcagtt ccggtacagt tataatggac ggaatggatg
    14581 ttcgttcttg gcagctggat catctccgtc agcaaattgc tcttgttccc caaacttctg
    14641 tactatttac cgggactatt cgtgaaaacc ttcaatgggg taagaaagac gccacagaaa
    14701 aagaatgttg ggaagctctg aaaatcgctc aggcagaaga atttgtccgt cagcttccaa
    14761 atggtttaga tacaaaagtc atggaaaatg ggaaaaattt ctctggcgga caaaaacagc
    14821 gactgacgat tgcaagagct ttgattgcca agccagcatt actgatttta gatgactctt
    14881 taagtgcgtt ggattatcaa acagacttgg atttgcgtaa ggcgctacag acttatcttg
    14941 gcagtacagt gattattatc tcccaacgtg tccgctctat tcaagaagca catcatatct
    15001 tagtgatgga tcaaggtaag attgctgctc agggtaccca tgaagaatta cttgctcaat
    15061 cagcagaata tcaggaaatc gtcgcatcac aggaggaaga atagttatga aagtaaaaaa
    15121 attatccttg cagacgctcc gccgattcat tccttacctt actgcctatg caaaagacat
    15181 ttggctagct gtgatactag gaatcatcaa tgggattgca acagttgtga tgacgttaca
    15241 aattggtcaa agtatcgatc aaatgattgg agaaggacag gtccgcttca atcgactgtt
    15301 ccatttactt attctattcg gtggtatcgt tttaatcaac gtagtcagtc aatggctcat
    15361 ccaagtgtta agcaatcggt tagcttactt atccgttgca aaattaagaa aagatgcatt
    15421 tgctcatctg aatcgattgc cacttcgtta ttatgatcaa aactcccacg gaaatatcgt
    15481 cagtcgattt acaaatgata tggacaatat ttccattgca atttctgcgg ccttcaatca
    15541 attattttct ggagtggcaa tcatcattct ttcgtttatt tttatgatgc gtctaagtcc
    15601 acttctgaca ttggtcgttc tttgttctac accaattatt ttccttgtga gttggatcgt
    15661 tgctcgtgct tcacaaacaa atttcgatag acagcaaagg attattgggg atatctcggg
    15721 ctttgtgacc gaacgaatcg gtaaccagaa aatcgtgaaa gcttttcagc aagaagaagc
    15781 tagtcaacag caatttgaac tgctaaatgc tgatctatat gaaaaaggac aacgggcaca
    15841 attttcttct tccttgacaa acccgtcttc tcgttttgta gatcaccttg cttatttatc
    15901 gattggttta gttggcggcc tattggcatt gaagagtggt tcgtcaatca ctgttggtgt
    15961 gatttccagc tttacgatct actcaagtca gttttctaaa ccatttatcg aactttctgg
    16021 aatcacgaca caactgcaaa ccgctttttc tggtctagaa cgagcatttg atttgatcga
    16081 tcagccagaa gaaaagcctg atttgccaga tgcctatgcc ttggaaccca aaaatatcaa
    16141 aggaaaagtc tcttttgatc atgtttcttt ttcttatgac cccaagcagc gtttgatcga
    16201 agatttcaat tttactgctt atccaggtca aaccattgct atagtaggaa aaacaggggc
    16261 cggaaaatcc acacttgtta atttgctgat gcgtttttat gacacaacaa aaggaacaat
    16321 tacagtcgat gaccatgaca tccgctctat ccaacgtgat acattacgta aaagttttgg
    16381 aatggtgtta caagatactt ggctatttga cagtacattg cgagaaaatc ttcgttttgg
    16441 gaatccggaa gcaagtgacg cagaaatcaa tgatgcccta aaagcctctt atatgtatga
    16501 atttgtagaa cgtttgccgg aaaaattaga tactaagatt ggcggtcaag ggttaaagat
    16561 atcagatgga caacgccaac tgttgacgat tgctcgaacg atgatcagta atccccctat
    16621 gttgatctta gatgaagcta ccagctcagt cgatacattg acagagaaaa aaatccaaca
    16681 agccttctta gcaatgatgg aaggaaaaac cagttttgtg attgcccatc gcctgtccac
    16741 aatcaaaaat gcggaccaga tattagtgat ggatcaggga gctattgtcg aaatgggcac
    16801 ccatgatgag ctgcttcaaa aagatggtta ttaccgacgg ctctatcaag cacaattcac
    16861 agcacaataa aaacaagcag tcttctggga tgggaagact gcttgttttt tatttagcgt
    16921 ggatcgctaa acttcttaaa atttt
//
LOCUS       DADVXV010000059        16716 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.060, whole genome shotgun sequence.
ACCESSION   DADVXV010000059 DADVXV010000000
VERSION     DADVXV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16716
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.060"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(253..1464)
                     /locus_tag="KB969_001912"
     CDS             complement(253..1464)
                     /locus_tag="KB969_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6869881.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKASSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLKHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFENLLKKDIK"
     gene            complement(1583..2218)
                     /locus_tag="KB969_001913"
     CDS             complement(1583..2218)
                     /locus_tag="KB969_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBB6869882.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAKNNVLQAQTGYFGTETVSIALHN"
     gene            complement(2354..3007)
                     /locus_tag="KB969_001914"
     CDS             complement(2354..3007)
                     /locus_tag="KB969_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869883.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKISKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQVTAEPSPTVISSSQSTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     AQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFFKYGIQ"
     gene            complement(3110..3316)
                     /locus_tag="KB969_001915"
     CDS             complement(3110..3316)
                     /locus_tag="KB969_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBB6869884.1"
                     /translation="MPSYVVLQVVLKEKFIGKGSQNLSELENTINRQCSKGYRLHTIS
                     TTNGGSKGFGGGDRIQATLVFESL"
     gene            complement(3392..4138)
                     /locus_tag="KB969_001916"
     CDS             complement(3392..4138)
                     /locus_tag="KB969_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004564412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869885.1"
                     /translation="MKQTTQQRLNQLMSERNLKQVDILNMSLPLQKETGIKMSKSHLS
                     QYVNGKSSPDQHKLYLLAKTLNVSEAWLLGYDVPKEDKKNNIPSIETIYNQLEKPRQT
                     KVYNFAEQQLEEQNRGNVVHFPKKEKLPTIKNSASAANPTELVYGDTVVEEEEFERVP
                     NNADFAVPIIGDSMEPVIRNGQFVFVKEQPDVEDGEIAIVEIDGDGVTCKEVYKDYES
                     QTIILRSINELYEDRVVSPEQIRIIGKVVF"
     gene            4298..4522
                     /locus_tag="KB969_001917"
     CDS             4298..4522
                     /locus_tag="KB969_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBB6869886.1"
                     /translation="MSFDYSKLSGRIVEKYGTQYNFSIALGLSERSLSLKLNNRVPWK
                     STELQKAIELLDIPKEEIGEYFFNLEVQNV"
     gene            4546..5307
                     /locus_tag="KB969_001918"
     CDS             4546..5307
                     /locus_tag="KB969_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBB6869887.1"
                     /translation="MNTQKFENNLFELEVKTENGESLFNAETVARSLGFVETKNGKEY
                     VRWRTVNGYLKKYLSQEVAKNDFISEPMVYKLAFKANNVLAEKFQDWLATEVLPQIRK
                     HGMYATDELLNNPDLLIEVATKLKEERTLRLIAEQRVNELQPKADYYDRILNNKGLVT
                     VSTIAKNYGMSAVSFNKLLHELGIQFNQSGTWLLYSKFQDKGYTHIEPFDYEDKNGNR
                     QVKTRMKWTQKGHIFLYETLKKNNYLPMIEREQTA"
     gene            5319..5576
                     /locus_tag="KB969_001919"
     CDS             5319..5576
                     /locus_tag="KB969_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869888.1"
                     /translation="MNEEMSQTIKVQKMIDDLTHAIDSQADKIIKELQGQKVWDAKML
                     FKTIKFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            5668..5919
                     /locus_tag="KB969_001920"
     CDS             5668..5919
                     /locus_tag="KB969_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6869889.1"
                     /translation="MEQLALVNLSDLKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWVNSTEH"
     gene            5895..6068
                     /locus_tag="KB969_001921"
     CDS             5895..6068
                     /locus_tag="KB969_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869890.1"
                     /translation="MGKFNRALVFSAPLIVYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYRAKKPTEGAD"
     gene            complement(6182..6589)
                     /locus_tag="KB969_001922"
     CDS             complement(6182..6589)
                     /locus_tag="KB969_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869891.1"
                     /translation="MSFDNTITISIILALVALISPSITAVINNKHVESMKDKEIELQK
                     HDSKTQTIQTTFSTFLNNVGICIGSNTDKNISAVKASGYAVLPYIQNEDIEVMKIFLS
                     RFGYGNTDAEQKSLETYLIDKVLPILNKSLEKL"
     gene            6750..6974
                     /locus_tag="KB969_001923"
     CDS             6750..6974
                     /locus_tag="KB969_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869892.1"
                     /translation="MISVKGLGDEIFEAMMSKAQQDIKEKIISAAAQGQTSCTVRSRG
                     TTPSFLLALEDEGILNIKRRDGSVRLFWQF"
     gene            6984..7178
                     /locus_tag="KB969_001924"
     CDS             6984..7178
                     /locus_tag="KB969_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869893.1"
                     /translation="MKDFDSLGARQQPPNEASPVGVDWQENPLYPGDTCYLTEEGYVP
                     VDAILEYVQQHYPKIELGGI"
     gene            7181..8203
                     /locus_tag="KB969_001925"
     CDS             7181..8203
                     /locus_tag="KB969_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBB6869894.1"
                     /translation="MANDLTQTTQRSLDEQVISNLGRLQEQGLEMPPGYSPQNALKSA
                     FFELTNNTGGNLLQMAANNQEMKTSISNALLDMVIQGLSPAKKQCYFIKYGNKVQLMR
                     SYFGTMAVLDRVTGGADITPVVVRQGDEFEVAMDGPNMVVKKHETKFENLDNEIIAAY
                     VVIKLTNGKETTTVMTKKQIDQSWAKSKMKDSGPQKEFPEEMAKRTVINRAAKTLINT
                     SNDNDLLVQAAKDTLENEFDNDRKDITPQTEKVATLEQKFFSNKKITEPIQKEPDPIV
                     IPDDIQNEVTRVADVPAHPEIEQAHLIENEDINPIQEELIDIPDFGREEGVEDVSEFE
                     DDEYPF"
     gene            8166..8981
                     /locus_tag="KB969_001926"
     CDS             8166..8981
                     /locus_tag="KB969_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBB6869895.1"
                     /translation="MSQNLKTTSTLSDENYYSNEADWQYMSTSQYKSFLKCEAAALAK
                     LKGDWAPTSDPKALLVGNYVHSYFESKEVHEAFKEENKSKMFSSRKPYGLLKDFQIAE
                     QMIERLKQEEAFMNIYQGEKETIVTGELFGTTWKGKIDCLNVEDEYFVDIKTTKDMHE
                     RKWNENYGSRETFIVNFGYVLQMAIYQELLLQQYGKMFMPIIAAVSKQTPSEAKLITI
                     DQDKMSYELIMLKENIERIVKVKNGEERPIPCGTCEYCRGNLSITGFTSMDDL"
     gene            8999..9781
                     /locus_tag="KB969_001927"
     CDS             8999..9781
                     /locus_tag="KB969_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869896.1"
                     /translation="MNLGYIKLYRKVTSSFVWTNSDMFKLWILCLMKASHEDRKFLFN
                     GQEVRLTSGQFVTGAHAIAKEYNEGVPSDKAIAWRTLWRWLKKFENEELLTIQSNARY
                     SVITIINWSDYQSSDKPVTSDGQSSDKPVTTNKNDKNDKNDKNNNPRNSRKTREYADD
                     DPNKKLAILLLKLIRKNRSLKEPDLNKWANTIRLTIEADKRTGKEVQDMIVWATNHDF
                     WSTVISSPTSLRKNFDTMVGQKNKRKQQNISNDELPETGEDW"
     gene            9781..10629
                     /locus_tag="KB969_001928"
     CDS             9781..10629
                     /locus_tag="KB969_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6869897.1"
                     /translation="MNKKLSAMAAPYGGLKTADHNCPKCGDPLYIWKTKNKDGTDRCG
                     PTCINKICGYREMVTKNQKEAIQKANEAMKKDAINRMLNSSMITDDAIWTFDFDGYKV
                     VDQETAQIKAMAQEWAKKIVNGSTIHAVITGRTGAGKTHLGAAVIKEVMRASNYKIAC
                     SFISYRELLEQLKFAMNDPEARKAVTGSLMAEIKKSDFVVIDDLGAELGRMEENNQAT
                     PYDVDVLTSLTEARLNKATIFTTNLSSKQLKHAYGERVFSRVMNGTKGNIAVFKTTTD
                     KRRNPV"
     gene            10626..10868
                     /locus_tag="KB969_001929"
     CDS             10626..10868
                     /locus_tag="KB969_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869898.1"
                     /translation="MTFVVKKMCYLDSRGRGEASVEFAKHHTTKEEADLVASVCGGEV
                     VEVIKPKRRFSKPKTKPVKKECCCPKSNQAWMRGAK"
     gene            11011..11379
                     /locus_tag="KB969_001930"
     CDS             11011..11379
                     /locus_tag="KB969_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBB6869899.1"
                     /translation="MATRSKYGNKKHEVDGITFDSITEAEYYDLALWQAQANGWKVKL
                     QERFELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQ
                     YQVPLILAKKYRNTFKEERF"
     gene            11394..11555
                     /locus_tag="KB969_001931"
     CDS             11394..11555
                     /locus_tag="KB969_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6869900.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            11552..11878
                     /locus_tag="KB969_001932"
     CDS             11552..11878
                     /locus_tag="KB969_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869901.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            11875..12690
                     /locus_tag="KB969_001933"
     CDS             11875..12690
                     /locus_tag="KB969_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBB6869902.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            12829..13140
                     /locus_tag="KB969_001934"
     CDS             12829..13140
                     /locus_tag="KB969_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBB6869903.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEGS
                     K"
     gene            13164..13382
                     /locus_tag="KB969_001935"
     CDS             13164..13382
                     /locus_tag="KB969_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869904.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            13379..13795
                     /locus_tag="KB969_001936"
     CDS             13379..13795
                     /locus_tag="KB969_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HBB6869905.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVIGNIYENSELLEVE"
     gene            13792..14130
                     /locus_tag="KB969_001937"
     CDS             13792..14130
                     /locus_tag="KB969_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869906.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMYGNSESAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            14127..14357
                     /locus_tag="KB969_001938"
     CDS             14127..14357
                     /locus_tag="KB969_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869907.1"
                     /translation="MKYEIPLSEADVQSIINGREVNKKLPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            14364..14567
                     /locus_tag="KB969_001939"
     CDS             14364..14567
                     /locus_tag="KB969_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBB6869908.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            14564..14860
                     /locus_tag="KB969_001940"
     CDS             14564..14860
                     /locus_tag="KB969_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869909.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWTAKSKENLAVVRLVDMELINDK"
     gene            14937..15350
                     /locus_tag="KB969_001941"
     CDS             14937..15350
                     /locus_tag="KB969_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBB6869910.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDALIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            15363..15749
                     /locus_tag="KB969_001942"
     CDS             15363..15749
                     /locus_tag="KB969_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869911.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            16300..16527
                     /locus_tag="KB969_001943"
     CDS             16300..16527
                     /locus_tag="KB969_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869912.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMLREAT
                     PKEIDQYKLVLIGIGWFKDEHIQTNMKRWLR"
BASE COUNT         5666 a         2726 c         3485 g         4839 t
ORIGIN      
        1 aataaaaaaa gaacagcgta aatgttttcg aaatgctttc gcaccaacat ttacctgttc
       61 cgtgggtttg gcacccaatg ggccgtgagg ggctcgaacc cgcgacccgc tgattaagag
      121 ttcgttattt aatggtattt taaatgaaga taagcgaatt tacagcattt ttaaatgctt
      181 atataccgca aattatccca agtttttgta tatcctaccc gagtttatac ccgaaaatat
      241 aattttttag tgttatttta tatctttttt taataggttt tcaaacgctg tagttgctgt
      301 atctttttct ttgcgtaaga catggccata aacattcatt gtagtattaa aatctcggtg
      361 tcccaatcgt ttttgaagct cttttggagt catattagga tcgctaagca aataggtagc
      421 tgatgtatgt ctaatgtcgt gaaaacgaat gtgacgcaaa ttgtgacgtt tggtgaatcg
      481 tttgaacttc ttatacagat aacttccacg tggcaaagtt ccatcttgtt ttgtatcaaa
      541 tataaaatag tgttttaatt tctttatatt taatttccaa cgaatctttt tattctcttt
      601 gattaattca tctaacatat caaatagata agcaggaccg gttactattt tttcatcatc
      661 atcatttttc aaacctggca gcaaccgaat atctgatttt ccatccactt ctgaaatccg
      721 ctgatgaaat cttatttctt gtttgtcaaa gtcaatatct ttttcttcta aagctgcaat
      781 ttctccttgt cttgctcctg taataaatgc tagaacaatt aaagttttaa tttctatgct
      841 ttcctcaaat gctgctttta gcattgcatg aatttcttct tccgaataag gttcttcgat
      901 attctttttt acgccttttt cttttggtat ttttacattt tccacaggat tttctttaat
      961 tgctccgtac tcatttttag ccatcaaaaa taagttgtta acggcgtata acatacgaag
     1021 ctttgtattt cttgataaag gtttatcaga gtttctccca ggatcttttg tattgattct
     1081 ttgagcatta acaacaattt tctttatcat gtatggtttg atatcgatta gagggataaa
     1141 atcaaattta tcaagaaatc tattctcgat cattcgctta tagttatgat aagactttgg
     1201 ctctaaattt ttttcggcct ctgaaagcca tatttttcta taaaattcac caaaagttat
     1261 attgaacaaa tccaacgaat catcggtcat tccttcgaat tgctctaacc agatgttcaa
     1321 ttctttatat gccgctcttt tactacttgc ttttatagtt ttgctttttc tttttgccga
     1381 gccatcaggt ttgtatccta atacagctct tagtctatat gtttcgttgt ctacttgttc
     1441 taagtatcct gttacttctg acataattga atcagctctc tttctctgat acaataggta
     1501 ctataaagaa gcctatcgta taggtttgtt tctttcttag aacacgctcg ctttggtcgg
     1561 tggggcgtgt tttttatact aattagttgt gaagagcaat tgaaactgtc tctgttccaa
     1621 agtaacctgt ttgtgcttgc aatacattat tttttgcatt tgcttgggct tcagagatat
     1681 caaaaactat tttaccagtt tgttgcatat caggatttaa gctttccata aagaaagagt
     1741 tagtgatatt accattttca tcttgatttg ccgacataga tgcagccgaa tcagcttcga
     1801 aagtttttcc atctgctttt aatttgaaga atgagctatc aacagtcaca gccttatcac
     1861 ctgcattttt tacagataag tcaactacta agaaagtgtc ttttgcgtta gtaggaagta
     1921 cagatgggcc aacttgtttt actacttcaa cggagtttac tttgtattcc attttcccta
     1981 cagcaacgtc atcaccgatt ttataagtct tttcttcttt tgttgtagtt tcttttgtag
     2041 tttctttatt agtacttgtt gatgttgcag tagctgaatc tttgttttca ccgccactta
     2101 gagcaccacc aataccaaaa aacaaaagta ctattaatac ccaaaaccat acccgtttat
     2161 aaaacggttt tttaacctta tacattttcc catcttgacc cataactttt tttgccattt
     2221 aaatattcct catttcttgt tataatatat ttgtgatctc agaaatgagg tatgagtccg
     2281 tgttgcagca cgggcttttt tatttataac ttttttagag attataggca aaatagtagg
     2341 gcataaaaat atattattga attccgtatt taaaaaatcc taattgaact tcaccggaag
     2401 tcttttgctg tgttgtacgc aatgcttctt cttcagacat tccattctgt actttccatg
     2461 caacaggcga catcccgtat ttgttaacaa aatcagtaag tgataaagtg tcagcgtctt
     2521 gctgagcgct tgtttgttgg tcttctggat tttgttgaga tgctgcttgt tgttctttct
     2581 gatcttgact gataatattg ccagcatcat ctgtagtcaa tccattttca taaagggcca
     2641 cgccgaaagc ttcccactct ttgttggacc aatttgcacg atcagctgga gttgactgta
     2701 aagtgcgttg tttcatctgt tcatatgttt cttcttgagg tgcggtttgg attgtactct
     2761 gactggagct tataactgtt gggctaggtt ccgccgtaac ttggttggag cttgtaactg
     2821 ttgaactaga atctgtttta gatgtagatt tgctagtaga tgaactggtt tcagttgttt
     2881 cttttgtttt acttattttt gtttcttggt tagaagtggc atctgttgat tcagcttttt
     2941 tattatttga acaagctgaa agtagcagag cagtacttaa caacaacata acgctaactt
     3001 ttttcatttt atactcctct tttctttgat acaataagtt gtaaagaagc ctactatagg
     3061 tttaacatcc cacgtccaca aactttggtc ggtgggcgtg tttttttgtt tatagacttt
     3121 cgaaaactaa agtagcttgg attctatcgc caccaccgaa acctttacta ccaccgtttg
     3181 tagtggaaat agtgtgtaat cgataacctt tagaacactg tctatttata gtgttttcaa
     3241 gttctgatag gttttgcgac ccttttccta taaacttttc ttttaataca acttgcaata
     3301 caacgtaact tggcatattc ttttccttct ttctactatg ataataaata ctaaccccta
     3361 gccggagcgc caactacgac tggggtattt tttagaatac gactttcccg attattctaa
     3421 tctgttccgg tgagacgact ctatcttcat ataattcgtt tatagagcgt agaataatcg
     3481 tttgactctc ataatcctta tatacttctt tacacgtcac accgtcacca tctatttcaa
     3541 cgatagcaat ctcaccgtct tccacgtctg gctgttcctt aacaaataca aattgtccat
     3601 tcctgataac tggttccatt gaatcgccta taataggaac agcaaaatca gcattgtttg
     3661 gaactctttc aaattcttct tcctctacaa ctgtatcgcc ataaactaat tcagtcgggt
     3721 tggcggcaga agctgaattt ttgattgtcg gaagtttttc ctttttagga aagtgcacca
     3781 cgtttcctcg attttgctct tcgagttgct gttcagcaaa gttgtagact tttgtttgtc
     3841 ttggtttttc taattgattg tagattgttt caatggatgg aatgttattt ttcttatctt
     3901 ctttaggaac atcgtaacca agcaaccatg cctcactcac atttaaagtt ttagccaaca
     3961 aataaagctt gtgttggtcg ggcgatgact taccattgac atattgcgat agatgacttt
     4021 ttgacatttt tattccagtt tctttttgca aaggtaaaga catattcaaa atatcaactt
     4081 gctttaaatt tctttcagac attaactgat taagtcgttg ctgagtcgtt tgcttcatct
     4141 tatacctcct ttctgatact tattatatac cttattgaac ataagttcaa taaaaaagtt
     4201 aaattaattt gaacttttat gttgacaatg ttttatgcag gagttatact ttggttacaa
     4261 agttcaaaac atttgaacta gaaaggagcg aactaatatg agttttgatt attctaagtt
     4321 gtcgggaaga attgttgaga aatatggaac gcaatacaat ttttcaatcg ctttaggttt
     4381 gtcggaaaga agtttgtcat taaagttgaa taaccgagta ccatggaaaa gcaccgaact
     4441 tcaaaaagcc attgaattgc tagatattcc aaaagaagaa attggcgaat atttttttaa
     4501 tttagaagtt caaaatgtct gaacttaaga aaggaattcg aaaaaatgaa cacacaaaaa
     4561 tttgaaaaca atctatttga attagaagtt aagacggaaa atggtgaatc gttatttaat
     4621 gctgaaacag tagcaagaag tttgggtttc gtggaaacaa aaaacggtaa agaatatgtt
     4681 cggtggagaa ctgtcaatgg atatttaaaa aaataccttt cgcaagaagt tgcgaaaaac
     4741 gactttatca gtgagccaat ggtttacaaa ttagccttta aagcaaacaa cgtacttgct
     4801 gaaaaattcc aagactggtt agcaacggaa gtcctacctc aaatccgaaa acacggcatg
     4861 tacgcaacag atgaactact taacaatcca gacttgctga ttgaagtagc aaccaaactc
     4921 aaagaagaac gcacgttacg attgatagct gaacaacgag taaatgaatt acaaccgaag
     4981 gcagactatt acgaccgaat cttgaacaac aaaggattag ttacagttag tacgattgct
     5041 aagaactacg gtatgagcgc tgtatcgttt aataaattgc tacatgaatt aggtatccag
     5101 ttcaatcaaa gtggcacatg gctgctatac agtaagttcc aagacaaagg atacacgcat
     5161 attgagccat ttgattatga agataaaaac ggcaatcggc aagtaaaaac aaggatgaaa
     5221 tggacgcaaa aaggacacat cttcttatat gaaacattga agaagaataa ttacttaccg
     5281 atgattgaac gtgaacaaac agcataggag gtaacactat gaacgaggaa atgagccaaa
     5341 caatcaaggt acaaaaaatg atagatgatc taacacatgc aattgatagc caagccgata
     5401 aaatcatcaa ggaattgcaa ggacaaaaag tttgggatgc aaaaatgctt ttcaagacta
     5461 tcaaatttga aatgaatcca acaaaaagaa agctcgccga tgtgttggaa gaaaagttgg
     5521 cttccgctat caacgagcaa gaattactat ttgaaaccga tacttttaac agctgatgtt
     5581 ttatagatga cagtttcatc cgaatctata tcattataga ttcgattatt gcaatgtacg
     5641 aattataaat acaggaggaa ataaccaatg gagcaactag ctttagttaa cctctcagac
     5701 cttaaagctt ctttggcaga atctgagatt gcaaatgaag tgtgggatac aaagcaagct
     5761 gcggaatatt taaaaaccac aacacgcacg ctgactaaag atgccgaatc tggaaagatt
     5821 ccagcagcga aagttggcag agagtggagg tttagtagta tcgctttgta tcagtatcta
     5881 aaaggaggaa aaacatgggt aaattcaaca gagcactagt gttcagcgca cccctaatcg
     5941 tctatgcttt aggactttgg ggaagcagac aagcattaat cggcacgatc gtttacatgg
     6001 tttggatttt tatggggctt gatgaagctg agtacagagc gaaaaagccc accgaggggg
     6061 ctgactaaag tgtggttctg tttattaggt gtttatctcg tggccgtttt agtaaataac
     6121 tacatgagaa aacgtggcga atactggtat acatcctatg cggttctagt atgtctaatg
     6181 cttacaattt ttctaatgat ttattcaaaa taggtaatac tttgtcaatc aaataagttt
     6241 caagagattt ttgttctgca tcagtgttgc cgtaaccaaa acggcttaag aaaattttca
     6301 taacctctat atcttcattt tgaatatatg gcaggactgc ataacctgat gcttttacag
     6361 cagatatatt tttatcagtg ttactaccaa tacaaatacc cacattgttg agaaatgttg
     6421 agaaagttgt ttgtattgtt tgggtttttg aatcgtgttt ttgtaattca atttctttat
     6481 ccttcatcga ttcaacatgc ttattattta taaccgctgt aatcgaaggg gatataagag
     6541 ctactaaagc taggataatc gaaattgtga tcgtgttatc gaaactcatt ttttcaccat
     6601 ccagttttta aaccattata tcaaaaagga gagaagaaat aatgcaagaa ttagtaattt
     6661 tgaaaaataa aaaaagacac gaacgccagc aagcatgatc gtgtccaaaa gaaaaatctt
     6721 ttaaaccatt ataacacagg aggaaataaa tgatctcagt taaagggtta ggcgatgaaa
     6781 tattcgaagc aatgatgagc aaagcacaac aggacatcaa agaaaaaatc atttctgctg
     6841 cagcgcaagg acaaactagc tgcactgttc gatcgagagg aacgacacca agttttcttt
     6901 tggcgctaga agatgaaggc attttgaata tcaaacgaag agatggcagc gtcagattgt
     6961 tttggcaatt ttaggaggcc gtgatgaaag attttgattc tttaggcgcc agacagcaac
     7021 caccaaatga agctagtcct gttggagttg attggcaaga aaatccgtta tatccaggtg
     7081 atacttgcta tctaacagaa gaaggctatg taccagtaga cgcaattcta gagtacgtcc
     7141 agcaacatta tccaaagatt gaattaggag gaatttagga atggcaaatg atttaacaca
     7201 aacaacacaa cgttcattag atgagcaggt aatcagtaat cttggacggt tacaagaaca
     7261 aggtttagaa atgccaccag gatatagtcc acaaaatgcg ttaaaaagtg cttttttcga
     7321 actcactaac aatacaggag gaaacttgtt gcagatggct gcaaacaatc aagaaatgaa
     7381 aacctccatt tctaatgcac ttttagacat ggttattcaa gggttatctc cagcaaaaaa
     7441 acaatgctat ttcattaaat acggaaacaa ggttcagcta atgcgttcat attttggaac
     7501 aatggcggtc cttgatcgtg taactggagg ggcagatatt acgcctgtag tcgttcgaca
     7561 aggtgatgag tttgaagttg caatggatgg accaaacatg gttgtcaaaa agcatgaaac
     7621 aaaattcgag aatttagaca atgaaatcat tgcagcctat gtagtcatca agttaacaaa
     7681 tggtaaagag accacaacag tcatgacgaa aaagcaaatc gatcaaagtt gggctaagtc
     7741 aaaaatgaaa gattctggac cgcaaaagga atttccagaa gaaatggcta aacggacagt
     7801 aatcaatcgg gcagctaaaa cattgatcaa cacaagcaac gacaacgatt tattagttca
     7861 agctgcaaaa gatacgttag aaaatgaatt tgacaatgat cggaaagata taacgccaca
     7921 aacagaaaaa gtggctactc tcgaacaaaa attcttttca aacaaaaaga ttactgaacc
     7981 aatacaaaaa gaaccagatc cgattgtgat tccagatgat atccaaaatg aagtaactcg
     8041 agttgctgat gtacctgccc atccagaaat agagcaagca catttgatcg aaaatgagga
     8101 tatcaatcca attcaagaag aattgataga tattccagac tttggacgcg aggaaggtgt
     8161 agaagatgtc tcagaatttg aagacgacga gtaccctttc tgatgagaat tattactcca
     8221 atgaagctga ctggcagtac atgtcaacat cacaatataa gtccttttta aaatgtgaag
     8281 ccgcagcctt agcaaagttg aaaggcgatt gggcaccgac gtcggatccc aaagccttac
     8341 tcgtaggaaa ctacgtacat tcttattttg aatcaaaaga agtacatgaa gcgttcaaag
     8401 aagaaaataa atccaaaatg ttttctagta ggaagccgta tggattgttg aaagatttcc
     8461 aaattgctga acaaatgatt gaacgactta agcaagaaga agcattcatg aacatttatc
     8521 aaggtgagaa agaaacgatc gtgactgggg aactatttgg aacgacatgg aaaggcaaga
     8581 ttgattgctt gaatgttgag gatgagtatt ttgttgatat caaaacaacc aaagacatgc
     8641 atgagcggaa atggaacgaa aactacggat caagagaaac gttcattgtc aattttggtt
     8701 acgtacttca aatggcaatc tatcaagagc ttcttttaca gcaatacgga aagatgttca
     8761 tgccaatcat cgctgcggta tcgaagcaaa cgcctagtga ggcgaagttg ataacgattg
     8821 atcaagataa gatgagctac gagctaatca tgctaaaaga aaatattgaa agaattgtca
     8881 aagtgaaaaa tggcgaagaa aggccgatac cttgcggtac gtgcgagtat tgtcgaggta
     8941 acctttcaat tactggattc actagcatgg acgatcttta aaaggaggtg ctttgcgaat
     9001 gaatctagga tacatcaagt tataccgtaa agtgactagt tcattcgttt ggaccaattc
     9061 cgatatgttc aagctatgga tattgtgttt aatgaaggct agtcatgaag atagaaaatt
     9121 tttatttaac ggtcaagaag tacgtttgac aagcggacaa ttcgtcacag gagcccatgc
     9181 aatagcaaaa gagtacaacg aaggagtccc gagtgacaaa gcaattgcat ggcgaacgct
     9241 atggagatgg cttaagaaat ttgaaaatga agaattattg acaatccaat cgaacgctag
     9301 atatagcgtt ataacaataa taaattggtc tgactatcaa tcgagtgaca agccagtgac
     9361 aagcgacgga caatcgagtg acaagccagt gacaacaaac aagaatgata agaatgataa
     9421 gaatgataag aataataatc ctcgcaactc tcgaaaaaca cgagagtatg cagatgacga
     9481 tccaaataaa aaattggcca ttcttttatt aaaactcatt cgaaagaatc gtagtctcaa
     9541 agaacccgat ttgaacaaat gggccaatac gattcgtttg acgattgaag ctgacaaacg
     9601 aactggaaaa gaagttcaag acatgattgt ttgggctact aaccatgatt tttggtccac
     9661 agtcatttca tcgccaacta gcttaagaaa aaatttcgat acaatggtgg gtcaaaaaaa
     9721 taaaagaaag caacaaaata tttctaatga tgagttacca gaaacaggtg aggattggta
     9781 atgaataaaa aactaagtgc aatggctgca ccttacggcg gattaaaaac agcagatcat
     9841 aattgcccga aatgtggtga tccattgtat atctggaaaa caaaaaataa agatggtact
     9901 gatcgatgcg gtcctacatg tatcaataag atttgtggtt atcgagaaat ggtaactaaa
     9961 aatcaaaaag aagctatcca aaaagcgaat gaagcaatga aaaaggacgc tatcaatcga
    10021 atgcttaaca gttcaatgat tacagatgat gccatatgga ccttcgattt tgatggatac
    10081 aaagtagttg atcaggaaac agcacaaata aaagcgatgg ctcaagaatg ggctaaaaaa
    10141 attgtaaatg gtagcacgat tcatgcagtg ataaccggta gaacaggagc cggcaaaacc
    10201 catctaggcg ctgcagtgat taaagaagtc atgagggcat ctaattataa aattgcttgt
    10261 tcatttatca gttatcgaga acttttagaa cagttgaaat ttgcaatgaa tgatccagaa
    10321 gcaagaaaag ccgtaacagg ttcgctgatg gctgagataa agaaatcaga tttcgtggta
    10381 atcgacgatt tgggtgcaga actaggaaga atggaagaaa acaaccaggc aacgccttat
    10441 gatgttgatg ttctcacatc gctcacagaa gctcgtctaa acaaagctac gatattcaca
    10501 accaatttat catcgaagca attaaaacac gcgtacggtg agcgagtgtt ctctcgtgta
    10561 atgaatggaa cgaaagggaa catagctgta ttcaaaacaa cgacagacaa aaggaggaat
    10621 ccagtttgac ctttgtagtg aaaaaaatgt gctacttaga tagccgaggg cgaggagaag
    10681 ctagtgtcga gtttgctaaa caccacacga ctaaagaaga ggctgacctt gttgcaagtg
    10741 tttgtggcgg cgaagtagtc gaagttatta aacccaaaag acgattttca aaacctaaga
    10801 caaagccagt gaaaaaagag tgttgttgtc cgaaaagtaa ccaagcatgg atgagaggtg
    10861 caaaatgact tgtttaaaat gcaacgatga aacagttatt tggtataaga cattgcttgg
    10921 atggtcaact tgtgaacctt gtccaatatg caatgaaaat ggacgacgtt cgaaagaacg
    10981 actcgaaaga ctaaagaagg agtatagcaa atggcaacaa gaagcaaata cggaaacaaa
    11041 aagcacgaag tagacggcat cacttttgat tctatcacgg aagcagagta ttacgatcta
    11101 gccttgtggc aagcacaggc gaatggttgg aaagtgaagc tccaggaaag gtttgagctg
    11161 atgccgaagt ttgaactaga gggcaagaag tatcgcaaga tcgagtatat tcccgacttc
    11221 acattttaca aaagcggcaa gctggtcaaa gtcgtagatg ttaaggggat gcagacaaaa
    11281 gactttaaga tcaaggcaaa gttgttctgt catcaatatc aagtgccgtt gatattagcc
    11341 aaaaaatatc ggaatacgtt caaggaagag cgtttttaac gaggtggtcc atcatgacaa
    11401 cagaagaagt gattcaaatg cgaattcgaa gccttcggcg tgagattgac gatctggaac
    11461 gaacaaaggc agtgatggtc aatgaaacgg ctagaaaggc aatcgatttg cacatagaga
    11521 atttaagaag ggaaatccgt agattggagg aatgagcgtg gataaggaag cggcttggcg
    11581 aaaattaatg ttgctgattc aagatgagaa ctggcaagaa gatgaagcag tggttgctga
    11641 agttcagcgt ctaggaaaga ttgctaacgg acgtatacga aaaaagccag acaaaagaaa
    11701 acagcgcaaa gggaaaatcg tcgttgtttt acacgaaggc aaaattttga tgcaaggaac
    11761 agctagtgag ctgtctgcag aaactggata tacgcgtggg actattcgaa cgtacgcttg
    11821 gcgaaatcac accgatcgaa aagggcacga atataagtat ttggaggaag aaaaatgaac
    11881 gaaaacaaat taatcaaatt gggtgtagca ggagcagtaa tcgtaggtat tggagttatc
    11941 ggaggattta agttcttcga aaaaatcgat aatggatatg tgggtgtgcg ctattcaatg
    12001 aacggcggta tcaaagatga agcactgacg caaggtgtga aatttgtagg gattgacaaa
    12061 gtgatccaat atccaattcg cttgcaaact atccaatcaa aaaatatttc agtatctaca
    12121 agcgacggca aaaagacaac gattgatatc aaatatgact acaaagttga ttcaactaaa
    12181 gcagcaaaaa tgtacaagga atttgggaat atcacttcgg aagatatcga aagtggatgg
    12241 ttaaaatcta agcttcaaaa ggtcgctcgt gaagtttatg cgaaatatag tctgcttgat
    12301 gtcctttcag gagattcctc taaagttgaa gctgaggtat taacgaactt tgctaaatca
    12361 gttgaatcta aagggtttga agtcgaagac gtaacacttg gtgttccaga tgtcgataaa
    12421 gaaacacaaa aatcaatcga tgcgatcatt cgagctggtc aagaaaatga aaaagcgaag
    12481 ctagacgcag aaactgcaaa aactcaagct gatagtgaag cttacaagaa aacaaaagct
    12541 gcagaagcag aggcagaatc taatcgcaaa gtcgccgaat cagtaacaga caatttgatt
    12601 cgttatgaag aagctcaagc tcgcaaaaag catggatggg taacagtaaa tggagcagat
    12661 actgtagtta cggatgaagc aggcaaataa tatgggattc tttatggcta aaattctctt
    12721 gttcttaggt ttagtaggag cagcatatct cgtgtatgcg ctcctttccc aaactgatga
    12781 caaagaagat gacaacaacg atgaaatgaa attttaggag gagaaataat ggacgaacta
    12841 atcacaaaag tagagcagtg ggctaaagac aagggactgg atcaagcaga tccaaaagca
    12901 cagtttttga aagtagctga ggaattcggg gaaatagctt cggcgatggc aagaagtaat
    12961 gatgaactat ttaaagatag cgtaggagac gttatcgtca cgctgattat cctttccatg
    13021 caaaaaggga caaacgtaca agagtgttta gaaatggcat acaacgaaat caaaggacgc
    13081 acagggaaaa tggtagatgg tgtattcgtg aagtcgagtg atttggaggg cagcaaatga
    13141 taaaaaagct cattcaattc agcatggatt tatatgatat cgaatcagga gcaacactat
    13201 ctgtggaatc ggaccatcta atcataaatt ttggtggaaa gcgccagatt attttgtggg
    13261 tagttgatga tgtactgttt ccagaaattg ttcatgattt cgaagaatca aaagcggttg
    13321 agtttgaaat agtgaaaaaa gtaatggaat tgattgaaaa atacgaggag gacagcgaat
    13381 gataccgaag tttagagcgt gggataaacg aaagaacgta atgagagatg tagccgtctt
    13441 gcattttact aaaaacggca aaacaaactt tattgaatat tggataaatc ctaccgaatt
    13501 gaaatcatat cacgtgcgaa acatcgacct catgcaatcc acaggaatga aagataagaa
    13561 tggtgtggat atatttgaag gggatatagt attagtcagc gtgcgaaatg gcttcgatta
    13621 cttagataat aaagtttgta ttgtcaaaaa ttcaatagat tattccggat tagtttgtgc
    13681 cactgttgat gaagacttag agtatcaaat ttttaacaca gagctgtttg aagaatacac
    13741 gtatgaagtc atcggaaata tatacgagaa tagcgagtta ttggaggtag agtgattatc
    13801 ttagctactg actacatcga ttctttaaaa gatgaaaatg ggaatgtccc agcattgcta
    13861 aattgtggaa ttaaaagcaa gaatagaatc attttgttac ggatatcggc tgatttagca
    13921 aaatatcttt atctgagcaa gacagcagta tattacactg cggctacacg ttatcagtac
    13981 aagggaaaaa caatcagtca ggattattat gatcgtttaa tcagtcctga tatgtatggg
    14041 aattcagaat cagcaattaa gctgtttggc gcaatagaga tatatgccga tgattttcca
    14101 aatttatggt tgaaggagga agcggaatga aatacgaaat accactaagt gaagcagacg
    14161 tccagtcaat tattaacggt cgggaggtta ataaaaaact tcctgatggt actgaattag
    14221 tcatcagaca aagttatttg aaagatatgg cagctccagt attaattgat cgttttaacg
    14281 tgactgattc tgtggtagag aaccacttga aagaatttcg atcaagtata aacgacactt
    14341 tcagattagg gagttgattg acaatgaaca ccagacaccg cagagtagca aaactaagaa
    14401 aacaggaact gaatgtacta aagacaaagt ttgaaaaaga atatggaatt tcagcagaag
    14461 aaacatataa agtggcaagt cagtgtgttg ctgatgcaag tgatgctatt cgtaagtttg
    14521 gaatttcgat attaagtgat gatcgtaaat gggaggaaaa agaatgaaac taaaagacgg
    14581 attttacgct agcagtcacg gtatcggcgg tttaatgcta gatatgccga caaagaatcc
    14641 taaaacacgt aagaaaccaa aagtcaaagt cggtgacatg gtccgctgtg aagcagagga
    14701 gttcatttat ccatttcgtg gatatgtaga acacgtctat aatcactcag cgatcattcg
    14761 cattgaaaac acgatggaat gtgataaatg gacagctaaa agcaaagaga atttagcagt
    14821 agtgagattg gtggatatgg aactaatcaa tgacaaataa aaaagccgga tcgctccgac
    14881 taacataata aaacagacaa gtttattata tcacataaaa ggagcagttt gaattgatgc
    14941 aattgttacg agaggtagat ttcaaacaga caagatgtaa tgcgagagat gtgctgaaga
    15001 actttcggcg tttggagcgg atggcaggtc gctctttgat agatattaag tcgccgatta
    15061 ttacggatat gccgaaggca ccgaagcacg gcaataaggc agaggatgca ttgattcaga
    15121 tgatggatat agaagcggag agagacgcga ttttagcggc tttgatggct cttagtctga
    15181 ttagtcgtca gatactctac tacagttttt gtgtgccaga cagcttctca aactacagaa
    15241 ttagccgtga agtgggttat tcagaaagaa gtatacaacg gatgaaatcg gaagctctaa
    15301 tagagtttgc agaagcatat aaacacggaa gaataattgc ttataaatag ggggaccata
    15361 taatgtggaa agattatgta tcgttgaaag agttgaaaaa agatcttgtt ttcaaaagaa
    15421 ttgtagaatg gtcagagagt gaattaattt tagaagatgg aaccaaaatg gaagttgtat
    15481 gtagcgaatc agattgctgc gcatgggccg aaggtgaatt caaaaatgta aagcttgatg
    15541 cagtgattac agatataaag atttttgata aaggtaaccg tctctataat ggtgacggac
    15601 atacctctta tgctgaagtc gttgtttatc ataatcgtaa tgagatcgct aaagcagaat
    15661 gcacagcgaa tgatgggaat ggcggctact attatagtgt ttgtgcttta aaggtcaaag
    15721 acaaactttg tatagtgact gacgcataaa aaaatggcgg ttttttggcg gaatgatggc
    15781 ggtttttagc catttatcag tgatattatg gtagtgtcga aagattagtg ataggtctga
    15841 gacaaaataa taataaaagg aacatcgttt tattattgtt tcacaattaa gcttcgatag
    15901 acagcaacgg aaatattaag aataaggatg tgaattttaa ctccttctaa attgttctta
    15961 ttatctatca tccgttgctg tttattgtta catacagatc gcttaggcgg tctttttatt
    16021 ttggccgaaa acctacattt tcgatggccg attattggag gaggaatagc atgttcaaac
    16081 tatctgaaat cattaagaag tccgacgttg agaaattaga gatgttaaaa aagaagttga
    16141 agaaatagca gtctcttcgt gaggctgttt tattttgctc acaaaaatag accactatcg
    16201 ggtaatagtg gtcaggaatt aaatgaaaaa gatgttaggg ttgttagcta agtataacat
    16261 cataacgctt acaaaacaat gcaagaagga taaattatta tgagaactta ctggtatgtg
    16321 tcattaaaca ataaatatcc gaagccaatg aaaggacagc ataggcgtgt agtcatgtct
    16381 gttcaaatga aggcgaagta ttcgattgta gaaatgctaa gagaagctac accaaaagag
    16441 attgatcagt ataagttggt tcttattggc attggttggt ttaaggatga acatattcaa
    16501 acaaacatga agaggtggtt gagatgaagt tatattatgt tgaaaaagca aattgttggg
    16561 tggttgaagg ctgtctgtca aagtacgcta cagatattat atctactcaa ttttcagagt
    16621 tgggattgaa ggttatcttt tgtggtgagt ttgtcagtgt gaaagaagcg gtattgccaa
    16681 tgacagcaaa gagcagacgc tcgcgtggtt caagtt
//
LOCUS       DADVXV010000060        16692 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.061, whole genome shotgun sequence.
ACCESSION   DADVXV010000060 DADVXV010000000
VERSION     DADVXV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.061"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            127..270
                     /locus_tag="KB969_001944"
     CDS             127..270
                     /locus_tag="KB969_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBB6869913.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            848..2431
                     /locus_tag="KB969_001945"
     CDS             848..2431
                     /locus_tag="KB969_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6869914.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(2868..4052)
                     /locus_tag="KB969_001946"
     CDS             complement(2868..4052)
                     /locus_tag="KB969_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBB6869915.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(4077..5084)
                     /locus_tag="KB969_001947"
     CDS             complement(4077..5084)
                     /locus_tag="KB969_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBB6869916.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            complement(5256..5615)
                     /locus_tag="KB969_001948"
     CDS             complement(5256..5615)
                     /locus_tag="KB969_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869917.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            complement(5587..5958)
                     /locus_tag="KB969_001949"
     CDS             complement(5587..5958)
                     /locus_tag="KB969_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBB6869918.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            complement(5975..6277)
                     /locus_tag="KB969_001950"
     CDS             complement(5975..6277)
                     /locus_tag="KB969_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869919.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            complement(6294..6764)
                     /locus_tag="KB969_001951"
     CDS             complement(6294..6764)
                     /locus_tag="KB969_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBB6869920.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            complement(6739..7017)
                     /locus_tag="KB969_001952"
     CDS             complement(6739..7017)
                     /locus_tag="KB969_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBB6869921.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            complement(7014..8063)
                     /locus_tag="KB969_001953"
     CDS             complement(7014..8063)
                     /locus_tag="KB969_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBB6869922.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            complement(8020..8949)
                     /gene="tadA"
                     /locus_tag="KB969_001954"
     CDS             complement(8020..8949)
                     /gene="tadA"
                     /locus_tag="KB969_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBB6869923.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            9081..10835
                     /gene="ade"
                     /locus_tag="KB969_001955"
     CDS             9081..10835
                     /gene="ade"
                     /locus_tag="KB969_001955"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBB6869924.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            complement(10933..11595)
                     /gene="trmB"
                     /locus_tag="KB969_001956"
     CDS             complement(10933..11595)
                     /gene="trmB"
                     /locus_tag="KB969_001956"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBB6869925.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(11665..12447)
                     /locus_tag="KB969_001957"
     CDS             complement(11665..12447)
                     /locus_tag="KB969_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBB6869926.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            complement(12651..13862)
                     /locus_tag="KB969_001958"
     CDS             complement(12651..13862)
                     /locus_tag="KB969_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6869927.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            complement(13855..14592)
                     /locus_tag="KB969_001959"
     CDS             complement(13855..14592)
                     /locus_tag="KB969_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869928.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            14730..15164
                     /locus_tag="KB969_001960"
     CDS             14730..15164
                     /locus_tag="KB969_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBB6869929.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            15157..15501
                     /locus_tag="KB969_001961"
     CDS             15157..15501
                     /locus_tag="KB969_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBB6869930.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            15681..16691
                     /locus_tag="KB969_001962"
     CDS             15681..16691
                     /locus_tag="KB969_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6869931.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
BASE COUNT         5323 a         3417 c         2940 g         5012 t
ORIGIN      
        1 tttaaaataa agggaaaaca gtcaatgagt tcaagtaaaa taaaaaaaag tgaacaccag
       61 ggcgattagt cgccctggtg tggtttaaaa cgacctaagc atgccaaagc ttattggttc
      121 gtcaatgtgg aagtttccga tgaatctgat acgaaaaaat atgaagtatc gatggcggat
      181 accgatttta tcgccaaact aaaattttat ttcgggttcg ggtaccgcga gaaggcaagt
      241 gctacattcg gtaaatcatt caagaattga tgaaaggcta ccgcttgcca ttgcaaccac
      301 aacgatactc ctgaacgcga tgttggtgag atttccaaag agaagagctg tttaatgcaa
      361 cggtattaag caaatggcaa aaggaagtca tgtagacaaa gttttttatc aaacaccata
      421 tgatttcgcc tgaacgctgg tttagctcag aatacaatga tgtggtccac gagacattac
      481 cctcagtcag ataaaaaaag ctctctgaca gaattacaca tcgataaata ttaagtaaat
      541 gtcagcgcta gttgaacttt ctgacacttt caggtacact ggaaaagaca actacacgaa
      601 ggagggaaaa tactatgatg cgcatgacta aaataacaag taatgaaaat taccaacgat
      661 accatatcgc atttagccat gcaattggtt ttacagttgc tgttgacggg acaagtttgt
      721 ccaaaacagt tgaattcacg taaaatcaat ggccatctca aggtattttt ctcatgataa
      781 tctgagttta aataacacag gccatggata accatggcct ttttgagtgg tctcaaggag
      841 agagatcatg atcatacaag caatttctat taaaaaaaca atcggcggga atccattatt
      901 tgaggattta tcctgtcaaa ttgaagctgg tgaaaaaatt gtcttagtcg gtatcaacgg
      961 aactggcaaa tcaacctttt tacaaatctt gaccggcaga gaaggtgtcg acagcggtgt
     1021 tatcagtcgc aaaaaaggct taaagatcgg gacggtcgaa caagaactta cagtttccga
     1081 agcgaccgtc aaccactact tgctccattc tgccgctgag atacaggacc tcaaacagca
     1141 aatgagtcgc tacgaagcat tgatgacaga accagataca aacttagaga agtgtctggc
     1201 ccgttacggt gagctgcagc atcgctttga agaactaggc ggttacgtat tagaagaccg
     1261 gattgcagcg atcttgcaag gcttagggat tccacaccgt caggaagcac ggttaacaga
     1321 acttagcgga ggcgaacgag ttaaagtcgc tttagccaaa attttagcag ccgatgccga
     1381 tttactttta ctcgatgaac cgaccaatca tttagatctt aacagtattc gctggttgga
     1441 aaactattta cagaatacaa aaaaatcggt tctggtcgtt tctcatgatc ggcaatttct
     1501 cgatcaagtc accacaaaaa catgggaact ggaagaaggt gcattgattg agtatcccgg
     1561 aaactacagc cgttttcgag tcttgaaaga agctcgcttg gctgagctga caaaaaatta
     1621 cgaactgcag caaaaagaag tccagcggtt gaaagtcatg attcgtcgtt ttcgtcagtg
     1681 ggcacatgaa ggagacaatg agtccttctt caaaaaagcc aaagaactgg aacgccgcct
     1741 ggcgaaactg acactcgtca aaccgccacc tcccccgaaa aatcggctgc aaagcttgtc
     1801 taatggtgga aaatctggca aagaagtttt catcattcaa aacttgcacc agcagtacgc
     1861 tgatcaagta ctattcaaag acagcagttt tgcagtctat cgtggagatc atttagccat
     1921 catcggcgac aatggtgcag gaaaatcaac cttactcaaa ttattactcg gtgaggaaaa
     1981 gccttacggt ggcaccatca aattaggtag tagcttgcaa atcggttatt tgccgcagca
     2041 gctgcagttt gccgatcccg atagccgttt gctggcttac gccatcacat tgactggaaa
     2101 cgaagaagtc gctcgacggc aattagccaa aagtggcttt tatcaaagcg atgtgggtaa
     2161 acggatcaaa gatttatccg gtggtgaaaa aatccgtttg gcgttgctga aactcttttt
     2221 agaaaaaatc aacgtcctga ttttggatga accaaccaat cacctcgaca gctatgctcg
     2281 agaagaaatt gaagaaatgc tgcaagacta tcaaggaacg ctcctagcag tcagccatga
     2341 ccgctacttt ttgcagcaac acttccaaga agcactcgtt attgatcagg agcagatcag
     2401 ccgccagccg ctcggccaac tgattgacta ggacgttttt tcgcaacaaa aaacttgatt
     2461 ttcatacctg tgctttcacg attcaggcaa agtacaggtg gaaaatcaag tttttattat
     2521 tcgatcaatg aatgtttcgg atcggttttc tagctaaaca taaagcgaag aataaagtcg
     2581 acagcccacg aggctgatct aaaaatgttt tttcttttta catatgtaat gtcccttata
     2641 aagatgaatg aaaataaaat attgggattt tcctgaaaat caataaataa aatgccagtc
     2701 ttttcccttt tgaccacttt tccaagcaaa attccctaag aagatcctgt aaaaaagaag
     2761 ggaaattgaa gttaaattac cattttgcgg tcttctccgc aaaaaaaaca catgcaagaa
     2821 ttccctcttg catgcgtttc atcttttatc ctaacgaatg ctttggctta gccgcgcaga
     2881 cgctccacat cacgggcaat cattagttcc tcatctgttg ggatcactaa tactcttact
     2941 tttgattctt ttgtagagat atctacttct tcaccacgca attcattcaa cgctggatcg
     3001 atttcacaac caaaccaaga catacctttg atgatttcac tacgtacatg tccgtcattc
     3061 tcgccgatac cagcagtaaa gacaattgca tcaacaccat tcatcgttgt cacataaccg
     3121 ccgatgtatt ttcggatgcg gtccacgaaa atgtcataag ctaaacgaat atgttctttt
     3181 tcatagttct tttcaagatc acgcatatca ctagacaatc ctgttaggcc tagcagacca
     3241 gatttcttgt tcaaaacatt gatcatttca tcaatatcaa tctctaattt ttccattaaa
     3301 tatgggagaa cagctggatc gatatcacct gaacgtgtac ccattgtcac cccagctaat
     3361 ggtgtgaatc ccatagaagt atccatggat ttacctccat cgactgctgt gatcgataca
     3421 ccatttccta agtggcaagt gatgattttt agttcttcga tcggtttgtt caataatttt
     3481 gccgcacgtt ccgacacata acgatgactt gtgccatgga agccatattt tcttactttg
     3541 aaatcttcat aataagacac cggtaagcta tataaataat tttgctttgg cattgttgag
     3601 tggaaagatg tatcgaatac agccacactc aaaatgtcag gtaaaatctt tttaaacgct
     3661 ttgatcccca ttaagtttgc aggattatgc aaaggagcaa attctgctaa ttcagcaatg
     3721 cggtccatta ctttctcatc gatcactact gaatccccat aagtttctcc tccgtgaaca
     3781 acacggtgcc ctactccggt gatttcatca taagagctta aaatttgcag ttcaatcaac
     3841 tgatctaaca gcatttttac tgctacttcg tggttttcga tatccatgat ttgttcgaat
     3901 ttttgattat cgccgtactt gatggtaaaa atagaatctt gtaaaccgat acgttcgacg
     3961 atccctttcg caactacggt ttcttctggc atttgatata attgccattt caaacttgaa
     4021 ctcccagcat tgattgcaat tgttttagac atatgactct ccttctcgtt gaatgattac
     4081 agagcagatg atttccagtt tttaaactcg ttgaaaaatt ccgtcacctt ctctggttct
     4141 tttaatgaag caagtttcac aagcaagact tcttttactt gttgtgcttg tggtcctttt
     4201 ttctgtaaga tcaaaatact tttttgcgat tgtttattac ggaacaattc atctggcaat
     4261 tgaatcattc cttgaagata accttcttct ttaaaccatt ttttgatttc ttcactttga
     4321 tccgtttcta aaaatccact cggcatcaaa aacaaaccaa aaccatccgg cttcacatat
     4381 ttcattgatt gctctagcaa taaatgatgt gcataactat ggccttcttc ggtacttgtt
     4441 aaaaactctt ttgctttttc gtcattcgga taataaccga ttggcaaatc gctgattgca
     4501 aaatcgacag gatctattaa taattcctgc aacccgtctt gatgaaagta ttgaacattt
     4561 gcttgtgtca aatcacttgt agaagctgcg acagccaaca atgtatcatc aatatccaca
     4621 ccaattcctt ctgtttggta ccccgcattc gataggttta aaagaactgt taataacaag
     4681 ttgcccattc ctgccgcaat atccagaatc ttaaccggtg cttttttatt tgtgtatagt
     4741 tgttcaataa gaaaaacaaa taaaaaaccg atactatcag gagtgagttg atggttcgcc
     4801 tgcaaatgtt ctgtctggct gcccttcaat aaaagtaatt gagacagtct gcgccattct
     4861 tctggctcga aagaaagttt cttcaactct tcataaagag ctgtgatccg ttgcgttgtc
     4921 tcttttgtcg gcactccatc caccacacgt acttgataat catctattaa attttctgca
     4981 ttttcgacat aggcttctaa aaaggaagtt cccaatgcat tctgtaaaag ctgaatagct
     5041 tccaggtttt gattaaaccc ttgttccatt ttttctggta acatggtgca cctcatttct
     5101 agatatatta taacaatttt ttcacctgtt taattctatc gaacaattga caaaatttca
     5161 atcgttttca ctgtttttta tttgtgaaac ggcaaacatt tttttattaa aaacagtgtt
     5221 ataacagaaa agagggcgtt ttcacgaaca ttccatcatt ctgtactagt atctgtatca
     5281 ttttttactt cttctgtgaa ccgaaagata aacggtgaga cttccacctc taagaatagg
     5341 gactgttgta cccactgata tgttacagat ccagttgtgt agtaaaaaac tccttccgaa
     5401 ctttcggcaa gcgtagactg ttccgataaa gccatctgct tcattatttt tgctatataa
     5461 taatttttga ttcgtatatt aagatccatt gacaaacggt agctttctaa tgctgccatc
     5521 aataaaaacg tacataaaag aaataaaagc aagacagaaa ataaaataga gcccttataa
     5581 cattttctac tgatcgtttt ttgtccatat ggcatatcca tcttctccat tttcaaagtg
     5641 tacataaaaa gaaattgtgt gttctttttc caataattga agctcagtga tacttgttaa
     5701 cataggttga tgtccgccgg aagttcttct tttacgtatc attgcctgat atctttcgat
     5761 gatatactgt ttatcctcga tcgtgtagtg cagttgctga tttttcacag agacattgtg
     5821 actgctcttg agttcttctt ctaattgtgc taaaaatatt agccactctt tttgatcttt
     5881 acgctgcaaa aattcactta cttggatggt ttgctgaatc aaaagattga atgtgagcaa
     5941 tagactgctc aatatcatca gtccaattag acattcaatc agcgtaaatg ctggaattac
     6001 ttgttttttc aatactgatc gcttctttct ccatattgac aaacactttt tcgattactc
     6061 cattattatc gacaatttgg atatcgtatg ggatcatttc ttcccttcgc tctggtcttt
     6121 tgtgatacat ccgctgcgtc ttgatatctt cataaatcat tcgaataaat agcagttcct
     6181 ccccactttt cttttctgcc tgaagcaaaa acagctggcc aaagctcact aagtagacac
     6241 agacagaagc gatcataagc gctgtaaggg actccaacaa aacaaatcct gttttattca
     6301 attctttttg tatagcgacc actccctatc tggaattgat acgtaatcgt ccgctctttt
     6361 tcttcccaat aaaattgata agcttttagt gaactttcat tcccggttct agcagcaaaa
     6421 gtaatagaag catggcgttt caaggtaatc tcatcaggaa tatctaatac ttcccaattt
     6481 attttatctg gattcggaac atgaaaaatg atttgattct cttcactatt ccaataaaag
     6541 cctgtttgga tctgattcac aatagcgatt ttttgcgtag aatagattcg tttttcaaat
     6601 tggccgaaaa attgatagac tgccaattca ttcttccatg cagaaaatgc gagaactgga
     6661 aaagaaagga tcgttgtaag taataaaatc agtaagagtg attcaaacaa cgtatatcct
     6721 gatgctaaaa ccttaccttc aaggccgctg atagatttct gcatgttctc gtttgatata
     6781 gccttcattc aacaattcct ccacagtagg aactcttcca ttattttgaa gcgcatagag
     6841 ctctttttgt gtgtctacca actggatgat cgcttcacga ctttcttggt ctacatgatt
     6901 cctataacgc gacaaattag ggacgaacaa caacactaat acactgatga tcagtaagac
     6961 gattagcatt tcgatcaatg taaaaccgct ataataagat atttttctct ttttcatggc
     7021 aaaacctcct ctatgcttcc gtaaacaggt aataaaacag cggcataaac taataaaatc
     7081 aaagccgcta cgcccaaaaa aatgattggc tgaataaaat gcatccagtg atgaagacgt
     7141 ttgaaaagct gttttcttgt ccattcgctg taaaaaatca gttctttacc taaacttccc
     7201 tttgcctctc cctgtaaaac aattttactg aattcttctg atagaaaacg ataattctgg
     7261 aactgctcag ccaatgacat acctgcctcc aatccttgaa tcaacttaga ggcaagatgc
     7321 tgaatcagac tttcttgttt cgtttccttt aagcagacta tgatttgcct taattcgaaa
     7381 ccttcatgaa aaagctttcc aatctctagt gacaaataag ccgattgata caaggaatat
     7441 atcggtccaa tcaataattg tctgcttatc cattcactct gatcaacagg agacaacttc
     7501 atcagacgat accttactag taaagccaat agagtaaccg ctaggatgaa tagtagaaca
     7561 taccaatgaa agacttgtat cagctgaata ccccaatgct cttgcatgac cattcctgaa
     7621 ccaataagct gaggcaaaac gaacaaccgc atactaaaca agatacctag caaaaaggtg
     7681 agcaatagca tcggatatgc aagcagcttt ttcaaatcat tgcgaaatcc ttcaacaagc
     7741 cgaaactgtt tggcaatttc caacaaagtt gtcggcagat tcccatgacg ttcagctaac
     7801 tcgatctgta ccagttgctc tgctccatat cctatttgcg aaagtacctc actaaacgct
     7861 tgcccttcct ttagctgatg ttggatattt gccaaaataa caggtggaaa cgaacggatc
     7921 gtgagtaata aataaaggga ttcttgcaga ctaaaaccag ataaaagcag ttctcccatg
     7981 gtttgtgcaa actggttttg ctggcttctt gttaatcctt tagaatagtt ctgactgcca
     8041 aatattttcc tgagcttctt cataactttc ctcccatgat ttttttactg attcttcctc
     8101 cataaattga taactccata aaacagaagg atggtgattg gcatcttcca aaagttcttg
     8161 ataaatgaca ccagctaaac attcagatag ctcttctttt ttctttgtca gttcatggat
     8221 tctgaccaat gtaccttcaa gattgcgtgc atgtacggtt gcaaaaaccc ggtgccctgt
     8281 tagtgctgct cttaccgcag catgtgcagt tgattcatct cttatctcgc caatgattag
     8341 caagtctgga cgatgccgta atgcgagtct caaaagtgta tcataagtct gtgctatttt
     8401 cggattgatc tgtagctgca gaaaaaacgg ttcttctatc tctacaggat cttcgatagt
     8461 aatcacttgc aatttttctt ccaaagccaa ccgatacatt agagaagtct tgcctgatcc
     8521 gactggtccg ctgaaaaggt ataatccacg tctgacggtt ttctgtaaaa tagttgcaaa
     8581 atctcgagaa ctaaagcaac gatggggtgt ttcaaaagta ccgtataata gccgaatcac
     8641 taaactctct cgttgaaggt aatctcctac agaagacaac cgcagacgaa cttcctgttt
     8701 ttctaaagaa taagtaaatg cacctaactg agcttttctt ttttctccga tatccatctg
     8761 tcccaaatac ttaaatcttg agatcagttg ctgtccatct gccgaagaga ctttcttcca
     8821 gaatgttcgt ttttttccat agcgaaaata gatgtaaaat acttctgaag ctggcaatat
     8881 atatacgtct tgggcatgtt tggcaaaact ttcacttatc atttgatccg ataatcgttt
     8941 tatttccatt attctcccct ccacaaaaaa catacgtctt tttgatcttt ttgtttcaaa
     9001 taaaatgaat ttacaaaaaa atattggcaa aaaccgaatt tatgttatac ttataaaaat
     9061 ttatcttggg aggcactcca ttggaaacaa cattaaggaa atatatcgaa gtagcaagta
     9121 aaaaaaagcc tgctgaccta gtgatcaagc atgctaagat cgtcaacgtc tttacgaaag
     9181 aaatcatgga aaaagatgta gcaatctgcg aaggaatgat cgtaggaatc ggtgaatacg
     9241 aaggaaaaag cgtacataat gctaatgggc aatatctagt gccaggattc atcgatggcc
     9301 atgtgcatat cgaaagctca cttttatcac caagcgaatt ttcaaaagta tccttgcttc
     9361 atggagttac tactgtagtg acagatcccc atgaaatagg aaacattgct gggagtacag
     9421 gtcttgagtt tatgatagaa gatgcaagac aaacactcat gaatatcttt tttatgctac
     9481 cttcttgtgt acctgtaacc ccttttgaga ccaatggtgc aaatttaaat gcaaaaaaat
     9541 tagccccttt tttacaaaaa cccgaagttt taggcttagc tgaagtcatg aactatcaag
     9601 cagtagcaaa taatgaaaca gacatcctag aaaagatcca attgatgcac cagcataaga
     9661 aaaaaattga cgggcatgca gctggtatcg gcatggaaga gttaaatgtt tatcctgcag
     9721 caggtattcg gacggatcat gaagctacaa ctgcaaaaga agctaaagaa cgtttggatc
     9781 ttggtatgta tttaatggtt cgagaaggga ccgttgcaaa agatctggca tcgctactac
     9841 cggcgatcac acctgaaaat tcaagaagat gcttctttgt caccgatgat aaactgatca
     9901 atgatttagt aaaagaagga tcaatcgatc atatcgtccg tcaagctatt gcacttggaa
     9961 tcgatccatt acaagccatt cagatggcaa cattgaatgc agcagaatgt tttgatttga
    10021 aaacactagg tgcgattgcc cctgggtatc aagctgattt cttcttaaca gacgatctta
    10081 ccaagctgcc aattcatgaa gttttctata agggaacatt agttgttcaa tctgggcaac
    10141 tccaagacca tttatttgct gatcattcaa attcatatac gtgttgtctg ccaaaactaa
    10201 acgctcaacc attaaatcca cattcgttag agctgcttct ttcttcttca caagcccatg
    10261 tgatcgaaat tatcccgaat agtctagtga ctaaagattt ggtagaaaaa gtggaccgac
    10321 aaggcgaacg attcattcct tcaatcgaaa aagaccaatt aaagattgcg gtgatcgagc
    10381 gtcaccatca aacgggaaac attggattag gcatagtgaa aggatttcag ctgaaacaag
    10441 gagcgatagc gacaacgatt gcccatgact cgcataatct agttgtcgtt gggacaaacg
    10501 acgaggatat gctgtatgct gctaatcttt tgattcaaaa aggtggcggg atgaccgttg
    10561 tcaacaatca gcaggaaata gcttgtgttt ctcttcctat aggcggaatc atgacacagg
    10621 aacctttttc gatcgtctat gaacagttga atgaattaat aactaaagca catcaactag
    10681 gagcagctaa aacctttgat ccttttttga cactttcttt cttaacatta tctgtcatac
    10741 ccgaattgaa gatcaccgac aaaggattat tttcattttc tcgcttccaa ttgattccac
    10801 cttgtggaaa aaccgatgaa ataaatacat tttaaatcaa ataaatccca gaaaatacat
    10861 tacatctgta atgttcattt tctgggattt atttatggat attaatgttt ttatgaaagc
    10921 agaaagttag tttcacagac ttttcttttt ggtcttatct tgaaattgag cttctactcg
    10981 ataaatacgt tgaccttttg aagaaaattt ttcttcatac tccgtcataa tattgccttc
    11041 aaattgactt tgatgtaaat ctaaccatac ctgtttgagg atcatgccat attgagaaaa
    11101 acttgccaga gaatactcaa acaatccttg attatctgtt ttgaaatgga tttctccatt
    11161 tggacgaaga atctgttcat ctacagcaag aaaagtctta tatgtcaatc gccgtttttc
    11221 atgacgtttt tttggccatg gatcggaaaa attcagatag atttgatcta cttcgctgtc
    11281 agcgaaatac tctgtcaacg ctgatccatc cacatgtaga agtttcaggt taggaagcgg
    11341 ttgttcgatc aacttgtcta gtgcaatcga aacaacactg acctgcattt ctactccaat
    11401 ataattgatt tcaggatggg cttttgccat tccagtgatg aactggcctt tccccatacc
    11461 aatctcaatg tggattggat gatcgttttc aaacaattca ttccattttc ccttccacaa
    11521 tgttggatca ctaattacaa aattcgggtg agccgctaac atttccgctg ctcccggacg
    11581 atttcggaca cgcattattt atctccattc ctttcctcta attaaaaagg tctggccaaa
    11641 tctccgcaga gtttgggcca aacctcagcc actgaaaatt cgttttaatt gtaaaatttc
    11701 ttcgttcatc cgtcgatgat cttcacgttt gcaatatctg gtgatttctt ggagcaaatt
    11761 catggccgca taccaatgaa atttttcaag catttcgtca gtcgggcgta tgccataact
    11821 gatcagccac tgattccagc tagacagtgg cacataattt cctaaaatcg ttgcaatatc
    11881 caccgcaggg tctgcaaaca tgattgaatc ccaatcgact agatataaat aatttttaca
    11941 tactaaccaa ttacgatggt ttacatctcc gtgtactact gataagtttt ccttatctat
    12001 tgacgggatc tgctcacgaa gaaaacgatg gacaatttgc agaaattgat ttttctggag
    12061 ttcttccggt aattcttttt catatttttg cagcatcttc tccggcgtca tgacacgacc
    12121 accgatacgg gtcagcatgg ttttaagaga atttgaatga tgtaaatggt acaaaacatc
    12181 aatcacgtcg tttctttgac caatctcatt aggagtcagc aagcgacctt ccagccactc
    12241 ttgtgctgtc aaagtatcgc cattccccgt tcgttttgtc caaacaagtt ttggtgtaat
    12301 tccttccctt gaaagagcag ccaacatcgg agtcgtgttt cgtttaataa agactttgtc
    12361 ctcatcacgc atgcctatgt atgtttttcc tgtgtcgcct ttgatgggac gtaaccgcca
    12421 ctcttggtct aactgaaact ccatcatgca ttctcccgtc ctcttactct ttgttttgca
    12481 gtacttatta ttctagtcgc ctgaacacta cacgtcaagc acatatacgt tctttttcat
    12541 ttaattgcca ttcaaaaaac cagcttttct caaaaaaaat agaacgaaca gcattcttac
    12601 tgtcaacgct ctatttttca ttctcatttt taccctacac agctttgttt tcagtctgac
    12661 atcttcttca aacgagttgg tacatatagt ttaacaaaga gcatagtaac aatcaaataa
    12721 gccgctagcg gaacccatcg ctgctgccca tctaatacga ctgcagcaat caaaccaaaa
    12781 ataaccgacg cgataattaa tacccatgtg agtagatact gaatcgcctg cttcttctga
    12841 ttcttatgga ttggataaag ctgaacgaga accatatagc ggaactggtt cgctaaaggt
    12901 aacagttgga aaccgatcaa atataaaaat aagaaaccga taatcagact aaaataaaag
    12961 tcgactactc cggcaatcaa taacccacct ataattacta atcggaaata aagaccacta
    13021 aaatcagaac ctcttgccaa tcttcttgca aacaagtaaa gataagtgtt ttttgattct
    13081 cttttaatat gagtcaatat aggatccaaa tagcgtcttc ttttgatctt tgccgtaatt
    13141 tcaggaacat ctgtgaataa attgataaat tgatagatct gatgcaacct atgttcttct
    13201 acatgcacca ttttctccca atccaatcct ttttcttgtt gcttccacaa aaaccagtaa
    13261 tatagacttg cctgtactaa tgcacctgct attcctgccc atattagcca ataaaatgat
    13321 agaaacaaaa agatcagaga agaaaaaaac cagcctaatt tccaataacg aataacttgt
    13381 tgatctagtc gaaacaattc tgctctcttg atttgcagat gactgaattt caaactccat
    13441 aatatgatca gatagacgaa aaacatcgaa aaggattgct ccgtactaac caccactaat
    13501 ggcatggcca atccgcatgc caatatcaaa aagatcaacg gaaaaatgca agaatagcga
    13561 aaagctcgtt ccaaataggt ttgcatttct ttttctttag gaagtaaaaa aacaatatct
    13621 gctgcctctg caaaagtagc catcttaccc acgaataaac agagcatcca aaatacagag
    13681 attatgagcc ctccaattgc aaacggtggc tgcagggttt tcaaccaatt agaataatat
    13741 aatcccacac cgccaatcaa gaaaagacaa actaaaacaa aatgatcgtt caatacataa
    13801 cgcatatatt tcatcatttt cttttgatgt cttgctaaac gtttttgaaa aaaactactc
    13861 atgtgcctgc tcctttgtta aagcaatata gatttcgtcc aaagaagaat ccggcagctg
    13921 aaattctttt ctcaacatct caagagaacc gtctgctcgt atctctccgt tatgtaagac
    13981 cacaaaacga tcacaatatt tttctgcagt agctaaaata tgcgtagaca tcaaaatacc
    14041 ggctccttct tttttcattt ctaccatcaa ttcaagcaat gcattgatag ctagtggatc
    14101 caagcctaaa aatggttcgt cgatgatata taaagaaggc tcgatcaaaa aggcgcataa
    14161 gatcatcact ttctgtttca ttccctttga aaaattagct gggaaccagt caagacgatt
    14221 agataaccga aaagtctcca acaacttttc tgctcttttc attgctatat ccataggtat
    14281 atcgtaggcc atcgcagtga cttcgatatg ttctctcaat gtcaattctt catataaaga
    14341 aggagtctct ggaatatacc caatttgttt gcgatattct tccgtatttt tctttaagga
    14401 tagatgattg atttctatcg ttccttttga agcttccagc agaccgataa tgtgcttgat
    14461 ggtcgtactt ttccctgctc cgttcagtcc aatcaaccct actatctctc caggctgtac
    14521 atcgaaactg atatctttta acacagggag atgtccgtac ccccctgtga catgatcgat
    14581 aattaaactc attctttttc ctccgccatt tatttttatt tattatacca cgaagaaaat
    14641 gacggtattt tgtttttttc cttacaatag ctttaactta tggtaaagtt aagctgaagt
    14701 atttattctt tatagaaagg atgttttata tggaaaactg tattttttgc aaaatcatca
    14761 atcaagaaat cccaagctat aaaatatatg aagacgacaa ggtctatgct tttttagaca
    14821 tctctcaagc aacgaaagga cacacattag ttgtgcctaa acgtcatgta gcagatattt
    14881 ttgaatatga tcccgaactt gcaggagagg ttttttcgcg tgtgcctaag attgctcaag
    14941 cattggaaaa agcttttcca gaaatgaaag gtcttaatat cttgaataac aaccgtgaac
    15001 tagcctatca atctgttttt cattcacata tccatttagt ccctcgctac agcaaagagg
    15061 atgatttttc tattcacttt gtcaatcatc aagatagtta tggatcggaa gaactaaaag
    15121 ctattcaaga aacaatcgta aagcaggtgt cctgcgatga ttaaaaactt tttcaaagga
    15181 ctgttatttg gagctgctgc tggcactgtc ggaggtctgt tattggcgcc caggagcggg
    15241 aatgaaacaa gaaagaaact gatcgaagaa ttggaagaag caacaactct gacaaatgat
    15301 ttaaataaca gcctgaatca ttttaaaagc gcattgatcg aaacaaaaga aacagctgaa
    15361 tctgtgattc ctgctttcca agaagcaatc aaaaaagata tcgaagattt taaattccaa
    15421 gccgaaccac gtatcacaca aatcaatgaa caagtagaaa aactaaaagc tgatctgcca
    15481 gagtatcctg aacaaatata ataatgatta ttttctcaac agatttaact atataagtga
    15541 gaaaagtttg cgtatttcct aggaatgtga tgaaattttg aattttgttt gaaactacca
    15601 cgacaacgtt tttaaaggaa atgggatatg gtatagttaa tatataaaaa taataactaa
    15661 ttacaggagt gcaaatttta atgaaaaaaa aatcaattat tttggcagct actagtgcgt
    15721 tggctgtttt aactctagca gcttgttcag gcgatactaa taaagatatc gcaacgatga
    15781 aaggcggaac gatcactgta tctgatttct atgatgaagc aaaacttgaa tcatcgaacc
    15841 aatccttagt acaacggatg atcatttata aagtattcaa taacaaatat ggcgataaag
    15901 taaccgataa gcaagtggat gcagaatacg acaaacaagc gaaatcatta ggtgatactt
    15961 ttgaatcaca attagaagct gctggatata cgaaagatac ttataaagaa tatattcgta
    16021 acaatttagc ttttgaagct ggcttgaaag ctcacgtaga tattacagat gacgatttga
    16081 aaactgcttg gaaatctttc catccagaag tagaagcaca aatcatcaaa ttatcaagtg
    16141 aagatgaagc aaaagatgtg aaaaaatcag cggatgatgg agatgatttc tctaaattag
    16201 ccaaagacaa atcaactgat acagagacaa aagaagatgg cggtaaagtt aaattcgact
    16261 caacgacaac aactattcct gcagaagtaa aagaagcagc tttcaaattg aaagacggtg
    16321 agatctccga tgttattact acaacaaatc ctacttctta tgcgacagaa tactacgttg
    16381 tcaaaatggt gaaaaaccaa aataaaggca atgacatgga taaatacaaa gatcaactaa
    16441 aagatatcgc tactgaaact aaactaagtg acaatgcatt cacaactaaa gtaatcggtg
    16501 aagaattaaa agatgcaaat gtaaaaatca aagatgatgc ctttgaaaat gtgttgagtg
    16561 cattcacaac aacttcatca agtacgaaag actcaagtga aactacagct tcaacaaaga
    16621 gttctgacac aaaatcaact gattcaacaa aagaatcttc aactgaagaa acaactgatt
    16681 catcaaaata aa
//
LOCUS       DADVXV010000061        16644 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.062, whole genome shotgun sequence.
ACCESSION   DADVXV010000061 DADVXV010000000
VERSION     DADVXV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.062"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..2131)
                     /locus_tag="KB969_001963"
     CDS             complement(<1..2131)
                     /locus_tag="KB969_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6869932.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWM"
     gene            complement(2128..2832)
                     /locus_tag="KB969_001964"
     CDS             complement(2128..2832)
                     /locus_tag="KB969_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6869933.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2844..5153)
                     /locus_tag="KB969_001965"
     CDS             complement(2844..5153)
                     /locus_tag="KB969_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6869934.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5348..5812)
                     /locus_tag="KB969_001966"
     CDS             complement(5348..5812)
                     /locus_tag="KB969_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869935.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5812..6438)
                     /locus_tag="KB969_001967"
     CDS             complement(5812..6438)
                     /locus_tag="KB969_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6869936.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6445..6810)
                     /locus_tag="KB969_001968"
     CDS             complement(6445..6810)
                     /locus_tag="KB969_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBB6869937.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6800..7138)
                     /locus_tag="KB969_001969"
     CDS             complement(6800..7138)
                     /locus_tag="KB969_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869938.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(7128..7454)
                     /locus_tag="KB969_001970"
     CDS             complement(7128..7454)
                     /locus_tag="KB969_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBB6869939.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7435..7713)
                     /locus_tag="KB969_001971"
     CDS             complement(7435..7713)
                     /locus_tag="KB969_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBB6869940.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7715..9079)
                     /locus_tag="KB969_001972"
     CDS             complement(7715..9079)
                     /locus_tag="KB969_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBB6869941.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(9092..9661)
                     /locus_tag="KB969_001973"
     CDS             complement(9092..9661)
                     /locus_tag="KB969_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBB6869942.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9633..10820)
                     /locus_tag="KB969_001974"
     CDS             complement(9633..10820)
                     /locus_tag="KB969_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBB6869943.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10884..12611)
                     /locus_tag="KB969_001975"
     CDS             complement(10884..12611)
                     /locus_tag="KB969_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBB6869944.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12608..13060)
                     /locus_tag="KB969_001976"
     CDS             complement(12608..13060)
                     /locus_tag="KB969_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBB6869945.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(13172..13552)
                     /locus_tag="KB969_001977"
     CDS             complement(13172..13552)
                     /locus_tag="KB969_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBB6869946.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13549..13935)
                     /locus_tag="KB969_001978"
     CDS             complement(13549..13935)
                     /locus_tag="KB969_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869947.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13937..14215)
                     /locus_tag="KB969_001979"
     CDS             complement(13937..14215)
                     /locus_tag="KB969_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869948.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            14263..14991
                     /locus_tag="KB969_001980"
     CDS             14263..14991
                     /locus_tag="KB969_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBB6869949.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(15122..15598)
                     /locus_tag="KB969_001981"
     CDS             complement(15122..15598)
                     /locus_tag="KB969_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBB6869950.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15558..15905)
                     /locus_tag="KB969_001982"
     CDS             complement(15558..15905)
                     /locus_tag="KB969_001982"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869951.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15892..16077)
                     /locus_tag="KB969_001983"
     CDS             complement(15892..16077)
                     /locus_tag="KB969_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869952.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(16078..16350)
                     /locus_tag="KB969_001984"
     CDS             complement(16078..16350)
                     /locus_tag="KB969_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBB6869953.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16347..16550)
                     /locus_tag="KB969_001985"
     CDS             complement(16347..16550)
                     /locus_tag="KB969_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869954.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
BASE COUNT         4668 a         3522 c         2583 g         5871 t
ORIGIN      
        1 ccatccattg tccatttgta aatgtccaaa taagcaatcg aacttgtgca tctaagctcg
       61 ttattggttc tttaatacct gcagcattaa ataagttttg aacataaact tttccatccc
      121 atgttgctgg accaacaaga ggatatgaag aaccatccca ctgaactaat ccgtatgctg
      181 gtccacctat ttgaacagta tcaggatcaa aagttcctcc tgtttcttgt tgaatgttcc
      241 ccaatattcc acatgcagat tgtttcgtaa atccgttatt acacaaaata tcgtatattc
      301 tccaagctct cttttctgca tctgttttta attcatcagg atacccacca ggtgtttctc
      361 ctccgccaga tggaccgcca ttttgtcctg gtatcacttc tttacctcta acagtaagtt
      421 ttccctgaat atctaaatca ccgaaataat atgcttttcc gtttcctaat aacacaaatc
      481 ctttttctgc agttggagaa attaaaatgt attttccatc gccatttgta cgtattacca
      541 aagaattttc ctcaagaggt gtaggtgtta cagcatttgg aaatggattt cctgctgaat
      601 ctgttgttcc gatcgttcca atggattctt ttctattcca gaattccata ccttttttgg
      661 ttagctccat gatttttttg ttttcattcc aaatttgaag cgtgcctttt acaagtttta
      721 acacatcacc ataagcatta aaggaagttt cgaatacttc tgcatttatt gttcctactt
      781 tgatgaagtc agcaacaatt tctccttttg atgtgatagc aataccgaac gggccattta
      841 ctccgttgtc tgaataacct aagccattta aattccaacg ccacactcgc tttgcattcg
      901 ccacatttgg agtatccatg ataagaatct ctgatggagc tttttctgga cgaaaaacga
      961 catgcccacc agaattacca gtgatccatg ccgtcgcatt caacacattt tgaactaacg
     1021 tttctgttcg attgtcgatt ttctttttca attcttgtgc ttgagtattt actgccgaag
     1081 tgtacagtga taaatcatta cctaaaacaa tatccttata tttcccaagc gttgggaaat
     1141 aagtgtattc gaccatacgc tcttttatct cgatatctag ctctttcgcc ctaacatgag
     1201 cgacatcacc aaagtgtaaa gacgctagct cttgatacat gtcaccgtat tcgagtgtgt
     1261 gttccaacgc caccatactg actgtatgag tagcttttgg ctcatggata cgatcattgt
     1321 caaataaggt tttgccccat ttgatcaatt catcaactgt tttacaatct ccgttttcac
     1381 gtttggcaat acgtcgattc tcgttggtta ctccatcaat ttctaaataa ccatattcga
     1441 taggttcttt gtcttcatca taatcgttat caggaacacc gccaaccaaa tacaaactat
     1501 tgacaattga ttcttcatca atttcttctt cgattgcttc taaattgatg ccaaaatcaa
     1561 tccgaaaacc attatctgat ccaatctgtt ttaccagttt caaatcatag ttatccatat
     1621 caagttccgc gctagtcacg ccagtcaaat tttgattacc gttatttgaa ccaatgattg
     1681 cttcaactgg cgcgacttgt cttgctgtaa attggtgcgt tgtccctaca ttcgaaagat
     1741 agttaaattt ttgatcaaat gccaaactgt ttttaagatt ggtcatgatc tgagacccat
     1801 tgccgttatc cgtaaacgac ttgacaataa agttcttatt ggccataaaa ccaatatgcc
     1861 gagctgttac agaaacggag gtcaaattct ttttgacatt ataaatttca aaatattgcc
     1921 atgatccatc tggtaccttc gcttttataa aatttccttt ttttaaataa gagcgatact
     1981 gtccgcttct tgaatagtta ccataaaaac gatattggcc attcagcaca cgattgattt
     2041 ctggcaaatc ttcccaatca actaacgacg ctccgttcac gctcaaatca tctggcattt
     2101 ttttataagc ataaataaat tcttgcgtca cagatacaca ctcctattcc aaaaccgcac
     2161 ttctttaaat tttccggata tttttacctg attccattca ggctgcaata ctggccaatc
     2221 accacgcgta aataaattca aaccttcttg tattgctttt ccaagctgag tatcaaccac
     2281 gattgttgca gctaacgtat taagtattgt taggctttta tcaccgacag cgatcgttat
     2341 atctcctccg ttcgattcta tttccagata gggatgtgca atttcgtcac catgatcaaa
     2401 aatatccata acactagaat gaaaaatttt aggtgcttca ccgatttttc ttttgagtgg
     2461 ctgacaacga aaagtaacat cgaatgtata aaagaagccc cactcgtttt cgaaagggac
     2521 ttctttatcc atgctgcaga tagcctctag atacttgtct ggatcattat gtgtgattaa
     2581 ttggctttta ccagtgagcc atcgtttgac ttctctcagt ttcgaatgtg gaatagtgat
     2641 cccttctatt tccaaatcaa aaggttcata gtcatcaaac gtctccgtca attctccgct
     2701 tcggccctga atcgtgtaag tttcgtatcg cttgttcggc ataatatctg gaagctctgc
     2761 ctcaatgatg caattcatat caattactgc attccgattt ttccaaataa aatttggttc
     2821 atctggattc ataaattgtc gactcaaata ggaacacctc ccaaatcacg aatagcctgt
     2881 ttgtttgctt tagcaaattt acgattcata cgatctaact cagatggatt gtttgcatcg
     2941 actttgccaa tgtgtatatg ctgttcaatg ctacctccag aaactcttcc actgatccct
     3001 ttgcgttttt cttcgtctga taatggagta actgtggttt taccattctt ggcagtcagt
     3061 aactcaggtc cagcttcacc aacaatcgct tgtccattga ttagatgacc gccttgtgct
     3121 aaataaggca gttttgaaat agaaaatgat tttccaccta caccaggaac ccattttggt
     3181 atctttatat tattcaatcc accaataaat ccattgatca atccaatcat ggcattaata
     3241 ggagctttcc ctacagcaac aataccatcg aaaatacctc caaaaatatc aactagacct
     3301 tgccatgctt ttgaccaatt ccctgtaaat actccagtga taaaatctag aaaaccactg
     3361 aaaattcgtt ttccagcatt ataaaaatta ttgaaatttg ctataacacc atcgaaaaat
     3421 ccaccaaaat aaccacttaa aaaattaaat atttcaacag ctacatctga aacacctttg
     3481 aagaaagaat tcactccatc atgaaaccat ttaacgttat tatatgccca aattagtcca
     3541 gtaactaatg cgccaatagc tataactgct aatgcaaacc agcctcccga cattccaaat
     3601 aaaccagcaa gtccttgcca aactcctata aaacttttaa cttccccaac gatttttgta
     3661 acagatccca taagtgaacc aagaacgatt agtactggtc caactgctgc cgctatacca
     3721 gcaattgtta tgatccaatt ctttgtatct tgatctagag acccccacca tttagagaat
     3781 tcctgtaata aggaagttgc tttttcaaaa aaaggcaaaa ggcttacttg gactgcttca
     3841 cctacgtcag ccattgctaa ttttgcattg ttcatagctt gatcggcttg atcaattggg
     3901 tcgagagtag catcgaatgt gtctcctaca gctcccccac tttctccagc agtttttgct
     3961 aaatcttcca ggttcaaagt acctctacga attgcatcgg ccattctagg accgccttta
     4021 gtcccgaata cttctgctgc tgcattgatg gcttctgttt cagaacctgc attttttacc
     4081 ttgtcttgta gttcttctag tccttgactt aaagattttc cgtctttcgc ataagccact
     4141 gttgctttag ataaactact taaagctgcg cttgaatcaa caccagattg ctcaaattgt
     4201 ccaagtaaag tgaccccttc accaaagctc aaccctaatt gtttaatttg tggtgcgcca
     4261 tcaattgctt tttgcatcaa gtcgtctaca gattgaccag tattctgcga tgttttcgtt
     4321 gttacatcaa ggacagaatt caaatcatca tattctagtc cataagcatc aatagcttgt
     4381 cgagcagata ttgctgattg cgaaacatct gtatcattga tttcagcgta ctgtaggaga
     4441 taattggttg aatcttccag ttttttatcc atgaatccaa attgtgtatt tacctcacca
     4501 atagcttccc caaccgtttg taaaggtaaa tgagtatttg aaccaacgtt tttgaaagac
     4561 tgtgaaagtc tatcagcttg atcacctgtt gctccggttt ttgtaatgat ggtatcaagt
     4621 gcctcgtcaa cttcaccaaa tgctgcaagt cctgctgctc ctgccgctac aataggcgcg
     4681 gttactccaa cagacatttt ttcaccaacg ccttttactt tctcacctgt ttcttcgatt
     4741 ttctggagtt tttttgctgt atcaacagaa acgtcacctt gttctttaag tgcatcgttc
     4801 gtctgttcta atgctgtacg aagtttattt tctccggttt cagaattgag taattgttta
     4861 taaagttttt ctgattcagc agaatattca ccggtttctt tgacagattt ttcatattcc
     4921 tctctcagca tttgagatcg ttgttcagcc aatcctaatt gtttttctaa tttttgttta
     4981 gccgctcgca atttttctgt ttgagttgca tccttgtcca tcgcagacac ttggtttttg
     5041 tactcggcag cggctaagtt catttctttg ttgatttctt tgattgtttt cgaataactg
     5101 acttcgccat tcgttttaaa attaagaacg acatcagatt ctttaccagc catttatctt
     5161 agcgctcctt tctaccacca aggcgattta tccatagtta cagattgagg tggttcaaaa
     5221 tcggtgtttt gttgtaacca ctgtaaataa gatttgagcc acaagttagg tgtagacttt
     5281 aaaaagaaac tctcactcca attcaataga gtgagagcaa cgtaaatata aaaactccaa
     5341 ggagttccta tctcttccga ttctttttgt ttttctttct ttttgcttgc gctttttgaa
     5401 agtcttgtgg cttcttggat ttttttaggt cttccacctg aaatgtctgg ctagcaaaaa
     5461 tttccataca ggtactataa gcagacaaca cctctccact cattcccaaa aatttgaaaa
     5521 tagtttctgg atcttcctct aaaccaccag tacgcagcat ggcataaatc aaggcacgca
     5581 tgatttttag atcactaggc gataagttag cagaagaaat ttgtccttct tttttagata
     5641 gcatggcgtt catatcagat tcaaattgcg aataatctcc accatacaca tctgctataa
     5701 attccatcgt ttgcatagta aatgaaatag ggaattctgc gccttgaata attacaacag
     5761 cagaattttt taagtcttca acgtgaattc cataatcaga taaccgagcc attaacccgc
     5821 acctccaact ttagccaatg ttttccactg ttcttcatcg tatacaggtt gagcaatgaa
     5881 tttattaaat aattctagag aagctccgtc tctatttgaa tcaaaacttg catacatcac
     5941 attattgtat ttcagtccga tggaaaccag atttgcagtt acatcgtcaa tttttgtttc
     6001 ttcctctgca gtggcatact cttcgtcaat cacattggat agttgtgtat taggatacca
     6061 aactgctttt ttaccgccat tttcaatatt tccaataaat ccaaaggcga agtacggaaa
     6121 ttctcgtgcg gtatttttgc taaacgttac tccgctttta gcaactaatc ctttgatttc
     6181 atccatcact tctatcggaa tacccacgtg atccaacgca agttcatgtt ttgtttctcg
     6241 cgacacacga cgaaacattt tgctggatgc ccatttttct aatgctgttc cattcccttt
     6301 gacaccgatt tttgtggcaa ttggcaatcg taaaacttca ctataagtcg gtgcagttcc
     6361 aacagaatct ggcgttgcca tcatcgcaat taaaatgtcg tccaatcctt caaaataaaa
     6421 agtatcttgt tttcccaatt aaaatcaccc ttcccataaa tcaagtattt ttctagtcat
     6481 aatttcttca attttttctt tgttttgttc atacgtacca cttgcaaaat gttgggcacg
     6541 ttgatttgtt gtgccatttt cggcaaagcg ccagtaaaag gccgtctctt caaattgaac
     6601 tttcacttga tcgttttcaa ctactacttt tatttgatcg cgcatatgtt tcttttttaa
     6661 gagcgactta ggaatattag gaagcaactg ctttagataa aagttagctg cttcttctaa
     6721 agattccaac gataattttt tcggatcaac ttttgaaagg tttcctaaat aatccgatat
     6781 ttcagaaaaa ccattcttat tacttggcat tttccacaca cctcacatat gtgtaatagt
     6841 tggttacggt atcgtcgttc tcatcacctt gtatacctgt aaaatctgaa tatggaatgc
     6901 cagcattttg cagcgcttgt tcaataacaa ctaaatcctg ttctgttcca agtgtaaaaa
     6961 aagagacttg gtaataaggt aattttttat agactttacc ggatgccatt tttttgctgt
     7021 tactcacatt tgagtacaca atgtatggat acatcgtccc taatctggct ttgtctctga
     7081 acactgctaa ctttgttgat ttcagcgctg ttttcaattc atcaaagcta atcgacataa
     7141 gctaaactca actccatttc tcttgcatcg ggattcgtat aaatgcgagt aatgttatac
     7201 gttacagaat caattttgag cgcacttaat ttctctgtga tggatttatc ccatctgact
     7261 ttaattcgtc tgacaacgtc tgtcttggct tgctgtgata aatatttttc ttgagaagtc
     7321 acaccgagtt cttcatagaa tattagacgc ttaaattcgt aaattgtagt tggacgatcg
     7381 tttccgtctg ttcctgtttt gatgtctagc aattcggctt tccatctgag attattagtc
     7441 tgtctcttcg gcattttgaa tcgctccttg cacgataaat ggcgtcatgg cattcatagc
     7501 tttgtcgagt tcatcctctg aaactctata ttcataggca atgccggcaa ccatcaaaat
     7561 aagatattct tgttggccac cagttgctgt tttgacataa tcttttgcca tatttaaata
     7621 aaaagagagc aaagaatcat ccatgccctc ttcaaaatga atatgtgatt tgaatttttc
     7681 ctctaaagac aattctttag tttgctcttc catcttaacc accaactggt tttgtaattt
     7741 cgtagcgata tactgccggt tcaaatggag aataaaccaa ttgaccatct agcaagttgt
     7801 aaatttggaa tccaatttga tttttaccag agaatttttc aacaagtttt tgaatttcca
     7861 aggcaccaat aacttcttga attttaaatg cagaaaaatc gccaaaatat aaaactggcg
     7921 tgtctggttc acccttttta tctgctgcat ctgtccaatc cacaggatag ccaactaatt
     7981 ggtaaccaat tccaccttct gcttgtgtga atggccgcaa caaaggaaat ccatcatctg
     8041 ttttcatttt ttcaatggca gtcaaagcag ctcgattaat aataaagcgt ccctttttca
     8101 tcacttctgt cactggtgta tttttaaatt cgattaatgc atcatataat ttttgcccag
     8161 cacctgaagc agttagatct aaaggttttt taaatgctac agcctttttg gctaatgcac
     8221 caggattttc atttccagcg tcatcaccat tgaacatata attgatttct ttacgcacat
     8281 aagctttttt caattcttcc acaacaatat cttcaactgg aacaccagac atttttaata
     8341 attttttagt tactgttgcc aaagcatcga attcggcagg attaagcaaa atttcatcaa
     8401 actgaatagc tgtttcagca atatcagttg aacgctcttt cttgtttaca ttcgcatctg
     8461 ctttcttcac aagaattgga tatttgacat ctcctgatgt tcgcaccact gttccgtatt
     8521 tacgaagtaa attttcttct tgagcataag taataacttc agatgcaatt acttctggga
     8581 cagtaactga accgttgcca gcttcaatcc ctaaagctcg agcttctgct tcagaaatat
     8641 ttccagctac aaaattagca aatgcttttc gtagttgttg atctttttgt ttcttggtca
     8701 tttttgcacg tgcctccaat ccgttcttaa ttgatccaag taatccatct cgttgctgtt
     8761 gagtaatcat tccagaacga ttttctgaac tatcttcact gtctgaatct tcttcttgat
     8821 cgttgtcttc accagaacgg ctttcgtctg aatccgtact attcgattga tcatctgtat
     8881 tgtcgtctgt ttcatcagtt ccagaatctg cgcctaattc gtctttaatt ccgttcaatt
     8941 catcaataac actgtcaatt tcttctttca cggcttctaa atctgcttcg cgtaattctc
     9001 ctgattcaac tttttcacgt aattcagtca atcgttgctc acgacgtgcc ttcatttttt
     9061 tcaataattc tttatccatg tatttttcct cctacgcttc tagcgcttga ttaatttttt
     9121 tgattaattt ttttctttct tcgacgtttt tttctaattc atcacgactt cttaatgcag
     9181 cttctgtatc ttcgtatgct ggcaaaggca caatagaaac ctcgtataat tccacttcat
     9241 ggattgttcg aagcattggt tcagaattgt agtcccacgt ttcttcagtc ggcacaaaac
     9301 caaaactaca ttggttgatg tctcctcgtt ccatagattt aactaagtcc cttgctaccg
     9361 ttgtgtccgg taaatcaact tcgaatttca aaccacgttc atcttcttca aggcgaaggg
     9421 ttccgctttt agtacgtcct agcacattgg accaatcgtg attgaacaaa caacgaacat
     9481 ccgaattact aattgccttt gagaatgcac caggaacaat cacttcgctt aagtcatccc
     9541 ataaaagtgt ttgactgttg aatacagcag cgtagccgct aatggtcctc gtatgagttt
     9601 cttcatcgga acgtgttgaa agattggtga tgtcaatcgt gcgaatttcc ttcttcttca
     9661 tttccatcac ctcctttcaa gtcttgatca ttcgttggta aggaatcatc tgttgcattt
     9721 ttctggccaa tcctagataa gtcatttgaa atatagatag cttgtgtttc tggagtattc
     9781 tgtttaggaa aaccaagcat ttctgccacg ttatctggac ttgtaatccc ggtacgaacg
     9841 atgttgtagc caatatttgt ttttgttgag taaggaacaa aatccaaaat attaattttc
     9901 cattccactc tatagccaga attaggcata aaaaaaagag cggtgtaatg ttcgctcttg
     9961 tttttcaata ttggtttgat tgctttgttg tgcagataca tcatcgcttt ttcaatatct
    10021 gtcttcatca gcgattgata cgtatcaaca ttgattccta gaaattttcc taagtctttt
    10081 ttgtaaacac ctaaataatt caaaattgcc gcgtcatcaa caggactttt taatgtctcg
    10141 atggaatatc cttttcccaa aggaatcatc ttaacagaat gatcactctc attttgcgtt
    10201 ccttccagtt gatccaatat agctttgaca atttttgttt gggcgctatt atttggattg
    10261 atgtgggcgt ctagtttaag catgaacgca agtaaaccgc ctttagtata tttgtccgtc
    10321 aaaacttttt cagcgctcag aacgccttct agagtgtttc ttgcaagatc aattattcca
    10381 gcacctttta atgaatcagt tccgatgttc ttaatgtgtc gaatcatttg accaggtatt
    10441 ttttgaccat tcatttcaaa ttcttcttga agtcgttcat tgattttagt tgttacaccg
    10501 tacgccaaat gaagctgatc cctatccgtt aatgggaatg tctcaccatt gatcaataaa
    10561 gtatttgttt ccaatttggt aaattcgaat cctgtcaaat aatcattggg actcttcaaa
    10621 atatttagta agtgatgatc tttgacttcg ttgccgtcgg gaccaataac aattggtgtg
    10681 gccaatgcca cctgattaga tatgtcttga actaattcat aaacatcaga agattccatg
    10741 atagatgaat ccgtcacata tctttgacca taacgtgtgt agtgtccaaa aatatcctcg
    10801 atatatccac gtttttccat aaaagaatag actgcattcg ataaccgatc acgtaatttc
    10861 aatttttttc accgcctttc tatttatcta tagatggaac ttaggtaatc atctaactca
    10921 tctgaatcaa tatctgtcat ttgattcatc gtttccttat gaccacacaa aaacgccacg
    10981 aacccatcaa tctttttctt tgattgacgt ttacttggcg ctttttgtcc attgatgtta
    11041 gtaattgcta caacgttcaa agtgcaataa aggaataatg gattatcaaa ttgaattcgt
    11101 ttctcataaa acaaccgttc gacatcgtca aaaggagcat tcaatacttt aggatattga
    11161 gcaacttcaa cgcattccaa tcctaagttt tctaatttct caacaagttt gtcactcatc
    11221 gctggatcat aattcacttg ctgaatatca tataaattca tgcagtcctc tatgtactgc
    11281 aaaatctgat cttgatcaat catttttccg tcgcaaaatt caacgaaacc ttgttcagcc
    11341 aaatcactgt aaggaacatt atcttctttt tctcgaaact ctaaatcttc attcggaata
    11401 aaataaagtt gctttacttt aagaaccgct ttaccatctt catcccatgt tgggaagttt
    11461 aaagatacac aggtcaaatc tcgtgtacgt gataaatcta aaccgatata acatggttcg
    11521 ccacttaaat caccaagttc ttgtgtggta actaaacatg gctctacttg atcctgttca
    11581 aagaaattat ccgcgccgtt cacaaataca tccaagtgtt tcgttagaaa ttcagctttg
    11641 gaatgagctg accgttgcgc tgttttaaat gccgattcta aagcagataa atcgactgat
    11701 attccccagt taggattgca catttcccag acttttctat ccgtccaatc ataattttta
    11761 tttggctcat agattagaac aaagtttgaa tcattatcat cacgtttcaa cacttctttt
    11821 gcttcgcgat atacacgcat tccaacagac gacgaacctt tcccagcagt tgagatatta
    11881 aacatcaatg gctgtggtaa agatatctga gcagacttaa aattgtcata ctgttccatt
    11941 ttctcctgtt tatgcaattc atcgttcaat acaaaatatg gattggatcc ctcgatatta
    12001 tcaatattct tggtttgaac aataaattta tttgagtaag ccatatcttc atgaatatag
    12061 tcataagtaa tactagaaac agttcccttt ggccccctaa atattttagt tccttcaagt
    12121 aggattggat tgtttaagat tgtaactgca aaaggtttgg cagcatattg cgcttgagca
    12181 aaatcagatg cgcaagcata gcaatcaact gataacgccc cttctccgta cattgcatat
    12241 cctaatgaac cgacagcaat caatgtttta ccattctttt ttggaatctg gacataagcc
    12301 tcacgagtaa cgcgtacaat ttggcctttt tcattttctt taacccaacc ataaatccaa
    12361 gaataaataa atttttccca gggttctaaa agaaacggtt ttcccaccat ttctcctttt
    12421 gtgtgaacaa taaatgattc tacccaatcc atcatttcat tcgcgcgatc tacatcaaac
    12481 caaatatctt ttcttttttt ccactgatac cagcgatcta ttgctaaacg aacggtctta
    12541 ggatacttct taggtttctt tcttacttct tttgcaaata aatcagcata atttacacca
    12601 ggttcaatca tttttcagca cctgccttct tacgccattt atttctgtgc gctgctagtt
    12661 catctactgg ctttacttct gggcgtgtaa tttcttcatc ttttcttgcg gtcgatcctc
    12721 cagcaattag tctaccagtt tttgctttgt ttgttaatcc taataaatct agagctttca
    12781 tcttcttatc tgcccaagtt tctacttgtt gtgccaatgg atgttttgat tgattagtag
    12841 ctcctgattt attcgtgaat ttttgcgtct ccggaaatcc tttttccttc cacaataaat
    12901 atttgtgttg gtaaatttca aaaatatcca agtatgattc gattaatgga tcaagagtga
    12961 tggtgtacaa atcagacaaa ttcattattt ctaagatacg agctttttca gcacttactt
    13021 tttcatcaat aatcgcttta cgttgcgctt tagtcgtcat ttttgtatac accccccttt
    13081 gttttttgaa aaatttgacc taacgatgcg cgtgactccc cgctacccta tctccccacg
    13141 cgaaaaaatt ttgaaaatga ataggggggc ttcaattgaa atacgaagga aaaacttttt
    13201 tgtcttccgt ttcgttttca acaattggat gacattttga acataatagc atgagattgt
    13261 ttggatcaag cttaagcagt tcgttgtctt tgattggtac aatgtgatgg acgtgtgctc
    13321 tctttccaaa tatgaactga ccacaccgct gacaatgacc accttctctt tcataaataa
    13381 attgacgcat atctttccat gcttgcgttc gatagaatgg tttgttctca tgatgataaa
    13441 cagactttgc ttgctgcttc ttcttgcgtg atctgcttga tctcttgtgt tcagtacagt
    13501 agataccctt tgctattttg ttcgtgcatc cgtcaaactg acagtatttc attctacttc
    13561 acgaataaga tttatgatat cgccttttgc acggatagca ccaggaatat caataccatg
    13621 tttcttagca tatgcacgca attcttttgc agtcatattg tccagttcat ccgtatcttc
    13681 agtggactga tcattagtag cttcgtctcc atcaaaatta gcagcagtgt ttccatcgct
    13741 atcaagaatt tcactgctat gagctatgag ttcgccattg acagcaacaa atgatttgcc
    13801 atcactcaaa attccttttt cttcttttac ttcaaaattt ggttcttgat ctttcggaac
    13861 aactactgtc cttttctttt ctgaatccca atactctgtt ccactaatgg atgttctaat
    13921 tttgatcatt gccattttaa ttctctcctt tgtaatttgt acggattact tttgcgccca
    13981 ttcgctcata ccattcaatc gtttcctgca gattgggtag agtgtgtgac aataaagaaa
    14041 taactaacgt attcattcca gttctgtaat catcattctc cacttgcaca tgtgcatgat
    14101 taccattcca attttctctg tacggactat tctctgcttc aattgctttc ttataaactt
    14161 tagccaaact tgattctact tcaatactaa gtaccgcttc atgaaaatca ttcatttgtt
    14221 tactctccta tcagatattt tgtggtatga tttataaaaa agatgcgagg tgttttaatg
    14281 cttcaagaag ttaatattaa gtatcgtgat cgtcaaaata cagagacaat ttatttgcca
    14341 aatagttgtc cgcattgcgg aaatataatg actccgtatg tgtattttgg ggtttcatca
    14401 tatagtgcgt tcgataatga tagaatcttt ggcgtattag tacagtgtat aaatgatgag
    14461 tgcaacaaat tttatagttt acaatttata aatacgttta atgaagatga aggatattct
    14521 gaaaatattt taattaaaga ttattaccgt ccgccgatta aaatagattt accagaaaat
    14581 attgaaaaag tttctcctac atttgttgat atttatactc aagccacaca agctaaatct
    14641 gagcaattgg aacaaattgc tggagttggt tatagaaaag ctctagaatt tctaattaaa
    14701 gattatgcaa tatctaaaaa ttcagaggat gaagataaaa taaaaaaaat gttattaggt
    14761 aaaacaattg aaaattattt gaatgatttt cctaaactcc aaagattagc caaagctgct
    14821 acttggattg gtaatgatga aacgcactat gttcgtagac atactaataa agatgttcat
    14881 gatatggatg catttattaa atcagcagcg caatttatcg cggctgatta tgatgctgat
    14941 ttagctgatc aatttataaa tggaaataac tttatgccaa ctactaatta aaagaataaa
    15001 agagccacag ataccaatta ataaaacggt tgggatatct tggctctttc atattttttt
    15061 gacactaata gaatatcatg ctgctaacaa tgtttacgaa catttagtga acagtgtaat
    15121 tttagaataa agagagttgt tctttgtact tctcgctatt gtaaaaatca atttcgtttt
    15181 cttttttcaa tcggtcagct tgtctgtgtt catactcatc taaaaagttc aatgtctttc
    15241 taatttctgc atgtcgctgt ctgacatacg atgagctata cccaacagat tcagcaatat
    15301 cttctaagct catttgatca acatatttca tcttaacaat ttgattatcg ataccagaaa
    15361 agctatctat cagcaataac atttcttctt tttgctcgat caacaattcc aattcatttt
    15421 ctatcttttg gatattctct tctaaagaag aagttctcga attcttttcg atgcggacgt
    15481 ttgctaaatc accacagacc catcgattca attcaagctt acttttatta agattccact
    15541 ttaagtaaag aatctgctca tctagttctt ggtaatcttt taaccaatga aatctcacaa
    15601 acgccacccc ttatggtaga atagtattgc gctgctatct cgaaaggggt agctttttta
    15661 ttttttctta gccgttccat tctggattgc cttttgttcc aaacgtcgtt ttttcttctt
    15721 aatctttgat tttgtttttc ccatacaatt ctcctttccg aaaacacatt ttgttcgatt
    15781 tttaatacta aataaaagtt ggccagaatt tttcgttcgt ctttactcat ctttttttga
    15841 ataagattac tagcataaaa atagttagta ccacgaaaat gaacaggtaa atcaattacg
    15901 ttcaccttct tcatgccagt tatcagccac tagaatcttt gcgttagtgc cgccaccgtt
    15961 ttcttttttg tatttttcaa atgctttata agcagctgtt tttgatttat agatttttcc
    16021 ggaaccgact gggaacatcc atgtgccctc tgtgatagct aagatgtata ctttcattta
    16081 attcacccct ttaatcccca acactacata tccggacttc tgcatgtaat cagtaatata
    16141 agtgatctct gctttgtatg agtcaccagt gtaactaaat gttggtctcg ttagtccagg
    16201 taattcatgt ttaatgtatt ttttatattc acgtagtatt aactgatcac caactttgaa
    16261 gtcacgatca ttcttgcgga tctcgaattg tttgcgtccg ctcgtcactg cttcaaaata
    16321 ttctggtagt atttttagtt cgtggatcat tctgtttcct ccttcaaaat tcgctcatca
    16381 tcaaaaagtg aatctccaca aaatccttct cccaaatatt tatcgttcat gtataagtca
    16441 accaaatatt tgtgatctgc ttctcgatat tcattaatat taacgatctt tattttgtaa
    16501 acattacctt cgtcgctcac tatcttgaat tgttctctga ctttcaccac cgttcctcct
    16561 ctttttgaaa aaattttagt gtttttgtaa gaccccctaa atcagctttt ttatttgata
    16621 taatacttgt atcgattaat caaa
//
LOCUS       DADVXV010000062        16615 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.063, whole genome shotgun sequence.
ACCESSION   DADVXV010000062 DADVXV010000000
VERSION     DADVXV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.063"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="KB969_001986"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="KB969_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBB6869955.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="KB969_001987"
     CDS             complement(680..1666)
                     /locus_tag="KB969_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBB6869956.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="KB969_001988"
     CDS             complement(1689..2255)
                     /locus_tag="KB969_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBB6869957.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="KB969_001989"
     CDS             complement(2269..2685)
                     /locus_tag="KB969_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6869958.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="KB969_001990"
     CDS             complement(3142..5076)
                     /locus_tag="KB969_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6869959.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5357..6313
                     /locus_tag="KB969_001991"
     CDS             5357..6313
                     /locus_tag="KB969_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBB6869960.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="KB969_001992"
     CDS             6403..7506
                     /locus_tag="KB969_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBB6869961.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="KB969_001993"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="KB969_001993"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBB6869962.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="KB969_001994"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="KB969_001994"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBB6869963.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGIGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="KB969_001995"
     CDS             complement(10887..12140)
                     /locus_tag="KB969_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6869964.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="KB969_001996"
     CDS             complement(12146..13069)
                     /locus_tag="KB969_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBB6869965.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="KB969_001997"
     CDS             complement(13290..15782)
                     /locus_tag="KB969_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBB6869966.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="KB969_001998"
     CDS             complement(15789..16256)
                     /locus_tag="KB969_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBB6869967.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16392..16465)
                     /locus_tag="KB969_001999"
     tRNA            complement(16392..16465)
                     /locus_tag="KB969_001999"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16429..16431),aa:Arg,seq:acg)
     gene            complement(16523..16596)
                     /locus_tag="KB969_002000"
     tRNA            complement(16523..16596)
                     /locus_tag="KB969_002000"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16560..16562),aa:Pro,seq:tgg)
BASE COUNT         4906 a         3476 c         2957 g         5276 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg attgcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtctcg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttgc tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca ataccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacgaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatcg acgcgcccaa gaggagtcga acccctaacc ttttgatccg tagtcaaaca
    16441 ctctatccag ttgagctatg ggcgcatatt caatttaaaa aaattataaa tcatttgaaa
    16501 acaaaaagca agataaaaaa aatcgggaag acaggattcg aacctgcgac cccttggtcc
    16561 caaaccaagt gctctaccaa gctgagctac ttcccgttta aaaaataaaa aagac
//
LOCUS       DADVXV010000063        16578 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.064, whole genome shotgun sequence.
ACCESSION   DADVXV010000063 DADVXV010000000
VERSION     DADVXV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16578
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.064"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..112)
                     /locus_tag="KB969_002001"
     CDS             complement(<1..112)
                     /locus_tag="KB969_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6869968.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLK"
     gene            complement(114..311)
                     /locus_tag="KB969_002002"
     CDS             complement(114..311)
                     /locus_tag="KB969_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBB6869969.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(705..2432)
                     /locus_tag="KB969_002003"
     CDS             complement(705..2432)
                     /locus_tag="KB969_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBB6869970.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2425..3618)
                     /locus_tag="KB969_002004"
     CDS             complement(2425..3618)
                     /locus_tag="KB969_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6869971.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3805..4449)
                     /locus_tag="KB969_002005"
     CDS             complement(3805..4449)
                     /locus_tag="KB969_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6869972.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4543..4677)
                     /locus_tag="KB969_002006"
     CDS             complement(4543..4677)
                     /locus_tag="KB969_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBB6869973.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4679..6811)
                     /gene="feoB"
                     /locus_tag="KB969_002007"
     CDS             complement(4679..6811)
                     /gene="feoB"
                     /locus_tag="KB969_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBB6869974.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6808..7281)
                     /locus_tag="KB969_002008"
     CDS             complement(6808..7281)
                     /locus_tag="KB969_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBB6869975.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7682..7906
                     /gene="nrdH"
                     /locus_tag="KB969_002009"
     CDS             7682..7906
                     /gene="nrdH"
                     /locus_tag="KB969_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBB6869976.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8065..10224
                     /gene="nrdE"
                     /locus_tag="KB969_002010"
     CDS             8065..10224
                     /gene="nrdE"
                     /locus_tag="KB969_002010"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBB6869977.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10274..11239
                     /gene="nrdF"
                     /locus_tag="KB969_002011"
     CDS             10274..11239
                     /gene="nrdF"
                     /locus_tag="KB969_002011"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBB6869978.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11328..12467)
                     /locus_tag="KB969_002012"
     CDS             complement(11328..12467)
                     /locus_tag="KB969_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6869979.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12776..13489)
                     /locus_tag="KB969_002013"
     CDS             complement(12776..13489)
                     /locus_tag="KB969_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBB6869980.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13743..14444)
                     /gene="nagB"
                     /locus_tag="KB969_002014"
     CDS             complement(13743..14444)
                     /gene="nagB"
                     /locus_tag="KB969_002014"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBB6869981.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14678..16210
                     /locus_tag="KB969_002015"
     CDS             14678..16210
                     /locus_tag="KB969_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6869982.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16401..>16578)
                     /locus_tag="KB969_002016"
     CDS             complement(16401..>16578)
                     /locus_tag="KB969_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6869983.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5146 a         3420 c         2869 g         5143 t
ORIGIN      
        1 attttaaata taccttttgt aaaacctcaa gaatatcaga atatttagga tctttactta
       61 tagatatatc attatataat tcatgaacaa tttgcttagc attttttttc attttagcac
      121 ttccctggaa ttgctccacc taaaaaacca cctatagaca ttcctgcaat acaagtagtt
      181 gccttggccc aatcgaccgt acatttattt ttagtgcaat acactccatt tccataatat
      241 tttccactat gagtggtacc cccatagata agttgtgtct ctttaataga caaaattttt
      301 aaatgtttca taatctaatc acccctaaat taatgttttt agactattat tctaacattc
      361 attaaatttc aaaaaacaat tccttcttga aacgtagcaa aataattcct gaataagaat
      421 ttaatcactt ttaagtatat aaactatgta tattctttaa tattttttga gaatgcactt
      481 cgtacataat aaactttaat cacattagtc tttcatacct acgatcgatc tctttgactc
      541 gcacccataa attcataata gtttgtcggc gtctttgaac gtttcgaaga tgagctacgc
      601 attctctttt tttatagaca aaaaagatag agacgaacat ggagcttcca aatttggata
      661 tttgatccaa ttttggaagc tccatttatt tcgtgtctgt ctttttattt tttccagctt
      721 tcgactaatt cttggttctc tttgatccag tcttttgctg cttgctgtgg atcttttcca
      781 ttgttgattt ccaacataac tttttccata tctttttctg accaatggaa attgtctaat
      841 actttgtaag cttctggctg gtcttctttc aatccttttc gaaccatcgt atggatctgc
      901 tcttcgcttc ccattccgtt ttcaggatct tctaagtatt tcagatcata tttggcaaac
      961 atccaatgag gtgtccatcc tgtaactaca attggttcgt gttttttgat cgcttgacct
     1021 agtgcaacgg tcattgctcc tgaagaagat gtctctactt tccagtcttt caagttgtca
     1081 tatttttgga tcgtgttttc agcagccgta actacaccag ctcctggctc gattcctatg
     1141 attttcttac ctgcctgatc ggttaactca tcgatcgaat ttacatccat gtaggctggc
     1201 actgctaaac caacttttgc tcctgtcaaa ttggcaccta ggtcttcgac ttgatcttta
     1261 tattgtgcat attgtgaacc atgagtttta ggtagccaag ctgaaaccat ggcatctgac
     1321 tcgccatttg aaacagattt ccacatgatt gaattatcta atggcgtcat cgttacatca
     1381 tagcccattt gtttcaatac ttcaccgact acatttgttg aagcaacttc tgtatcccat
     1441 tcaacataag ataagttgat acgttttgtt tctttggcag atgaaaaact ccctatacca
     1501 atcgcaccta agatcactac tactacagca ccaatgatca gtccttgacg ttttttactt
     1561 ttctgtgttg ttgctcctgc agctttttta ttgtttggct ggttcaaatg ctgtgtaaaa
     1621 cggtcaatga tgattgctaa gataactaat gcaaccccgt tgacaaatcc attcccgact
     1681 tgtgctcttt gcaatgctga taatacgccg cgtcctaagc cgggtgcacc gatcatagag
     1741 gcaataacga ccattgaaag tgacagcatt gttgtttgat tgatccctgc catgatcgta
     1801 cttttagcta aaggcaattc tagtttgaat agtttttgac gacttgtgct cccgaatgaa
     1861 tcagaagctt ctactaattc tttaggaact tgtcgaatcc ctaaattcgt aaaacgaacg
     1921 gttggtggca gagcaaagat gactgaggca aatacccctg gaaccatccc gataccgaaa
     1981 aatgcaactg ctggaatcaa ataaacgaat cctggcattg tctgcataaa gtcaaggatc
     2041 ggtttgataa tactttgggc tttactgctt tttgccatca agatccctaa tggtacccca
     2101 atgatgatcg agatcacact agataaaaga acaagtgtga cagtattcat caaatcattc
     2161 catagacctt ggttataaat aaaccataga ccgattaatg tgaacaacgt aagtcctgga
     2221 cgtttcttag aaataaagaa agctgctacc gtcaataaca agataaacaa aggagctgga
     2281 atcactaaca gtaaatttgt aatccccgac atcactgcct gtccaatcgt ttgtaaaaat
     2341 gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga tattttctac ccagtttgcc
     2401 actggtaatt gatagttcaa tagattattc atgttcactc acctcgcttg tttctgctaa
     2461 tgcttcaatc acactacctc ggatgacgac accttttaat tttccatcct ctacaactgc
     2521 aagtggagtc ggtgagtcat aaataatatt gaaaatatca cttaccacca tgtctttccc
     2581 aatcaccgtc acattttcat ctaggaagtc gatcaatgga cgtttttgct tcctagcttc
     2641 taacgcttga tctgcagtga tgatcccttt caggtgtctc tttctgtcaa cagccatcag
     2701 catgctgact tcttcattac gcatccttgt caatgcaacg tttggtccat cagattcgat
     2761 attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta agcactttgg aacgatcgac
     2821 ttcttccaca aattcacgta cataatcatt tgctggattg gtcaatattt cttcacctgt
     2881 tccgatctgc atgatttcgc cgtctttcat caaggcgatt ctgtccccaa tccgtaaagc
     2941 ttcattcaaa tcatgggtaa tgaaaataat cgttttttga acattggctt gcaggtccag
     3001 taattcgtct tgcatttctc gccggatcag cggatcaaga gccgagaacg cttcgtccat
     3061 cagcaagatc tcaggatcat ttgctaaagc tctggctagg ccaacccgtt gttgcatccc
     3121 accagataac tgactaggat attggtcttt aaatgaaagc aaactagaat tttctaatgc
     3181 tttttctgct ttttcttgtc gttcttcttt aggtacacca cggacttcta acccgtattc
     3241 tgtattttcc aagatcgttc gatgtggaaa cagaccgaag ttttggaaaa ccatattgat
     3301 tttatgacga cggacttctc gcaattcttc tttgcttaac ttcgatacat cttctccatc
     3361 aatatagata ctgcccgaag ttggctcaat cagacgattc aatagacgga tcaatgtgga
     3421 tttcccactc ccggaaagcc ccatgatcac gaagatttct ccttctttta cgtcaaaatt
     3481 cacgtcatac acaccaaccg ttgcaccggt tttctttaaa atctccgttt tcggctggtg
     3541 atcattcatc atatctaaag cggcttgtgt ctttttacca aatatctttg ttaaatgttt
     3601 tacttctact tttaccaaac aaattctcct tttttatgta aattcatttt tctttctgaa
     3661 aaaagtgacc acactatgtt aacatcatgt agtcactttg tcaaaaatga aagaaatttg
     3721 cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa taaaaggttt agccaagtta
     3781 atattttttt aatatttcac acaatcattc tgcaagctga tgctccgggt aaaaaaagtt
     3841 tgtcatacgc tgtagtgtat attcatttcc aataaaatga acgatgtccc ctgccgtaaa
     3901 tttagcatag gggccaggtg aaacaagcag ttcttcatta tgagaaattg cgataactgt
     3961 ggcgccagtc gcctgccaga tattcaactc gctaattgaa cggtccagat gcattgcttt
     4021 ttctgataaa gataattcaa acggaagtaa aggattcatc ttatgtattc gcttcgtttg
     4081 attgaccagc tgatccaata attgagaaaa atgattcagc tcatcttgtt gcttctccac
     4141 acttgccatg atttctgctt ttgtatcttg gatggattgt acatcttgat attgcaatag
     4201 gaaatctttt gctttttcct tcgaagcaac aaatgcccca cttccatgcc gtacttccat
     4261 gattccaaga tctaccagca cattgatagc cttgcgggta gtctcaggag aagcattgta
     4321 cgtactggca agtgttgagc gggcatggat cttctcaccc actttatatc ggttttcaac
     4381 gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc gggcggacga tttttttctt
     4441 tccagacatt ttctttcctc tttctttttt tactttccct catcttacta tgctctagca
     4501 aaataagcaa aaaaggggag aatagcctct tgcaacgact gatcatcgct tgatctgttc
     4561 cttttttact gggcaagctg tttgacagtc atcacaattc ttaccggatt ttaaacgagt
     4621 atagacaatt gcgcctgcac ttccaaagat taacacactt aataagaatg tcgccatcct
     4681 attcctctcc ttctaatgac aatatagtat aaaactggtt cttggatttt ggctgacgga
     4741 acaaaacata aacgagtcct atcatcagta aaatagcaag atacgtccct aacgctacct
     4801 gtccaccctc caataagtgt cccaactgat aaatcacaaa actaactaaa taagctaaac
     4861 cgcattgata gcctatggcg atccaagtcc atttcttggc attcatttcc cgatggatag
     4921 ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa ggctaacaat gaataagctg
     4981 ctgcgggagt atatgtgtgt tgtagcactt gccagatttc tctgccattt tcggatactt
     5041 ccgcatgacc aaacaaaata ccaaatgtgc caataatatt ttctttagcg accaatcctg
     5101 taatcgctgc gactgttcct tgccagtttc cccaaccaag cggctgaaaa acaactgcca
     5161 ggattcgccc gaaaaaggct aagatacttt ggtcttcaga aacaggttga gcataaaaat
     5221 tataagaaga gctgaaccag atcacgatac tagaaacaaa gataatcgtt cctgcttttt
     5281 taacaaaaga cttgctgcgg tcataggttt gtcttaggac cgctgaccat tgaggaaaat
     5341 gatatgcggg caattccatg ataaaaggag ctgtatctcc agcaaacaaa cgtgtttttt
     5401 tcaagctgat tccagagaaa ataattgcag tcataccaag aaaataggca gaaggagcta
     5461 cccaagattg atgaggaaaa aaggcccctg ctactaaggc aataatcggc aactttgcag
     5521 aacaaggcat gaaggttgtg accatgatcg tcaaacgacg atcttgctcg ttttcaatcg
     5581 tgcgactggc catgacgcct ggcactccac atcctgtagc aatcagcata ggaatgaagg
     5641 attttcctga aagaccgaat ttcctgaaaa gtcgatccat gacaaaagcg atcctcgcca
     5701 tatatccgca gtcttccaga aagctcaagc ataaaaacaa tataatcaat tgcggtagaa
     5761 atcctaacac tgctcccacg cctgcgatga tgccgttcaa gatcagctcc tgcatccatc
     5821 ccgctacttg ccattcagct aacaatctgc caacatgttc tggtaaccat gtaccaaaca
     5881 atgtgtcatt gatccaatct gtccccattg ttcctactgt ttgaatagcc agataataga
     5941 tcagccacat cacaaatgcg aagatcggca aggctaacca acgattcgtt gcaatctgat
     6001 cgattttgtc actcatcgat aattggaaag aatcatttga cacaacacag agtgtacata
     6061 gttgggtaat aaattcataa cgttcattga ccagaatcgt ctcactatcg tcgtccaata
     6121 gtttctctgt taactggatc agttgctcga tctctttttg ctgagaaact gctatctcgt
     6181 aatcctctct taccttctga tctcgttcaa aatatttcat tgcataccag cgtttcttgc
     6241 cgctttgttc tcctagtaca tcttcaattt catgtaaagc tgcttctaaa cgtggatcat
     6301 atgtacaggg aacaggaata gaaggccgct tttttgcaga ctcctgaatc ttttcgatta
     6361 gtttttcgat tccttgcttt ttcaatacgc tgattggtaa aactggtaca ccaagaccat
     6421 aggaaagctt ttctagattg attttttttc cttctttttt gatgacatcc atcatattca
     6481 gaccaatgat cataggaatg tctaaatcca ataactgcgt agttaaataa agatttcgtt
     6541 ctaaattggt agcatcaata atgttgatga tcagttcagg ctgttcctga accaaataat
     6601 ctcttgcaat cacttcttct ggtgtataag gagacaaaga atagatgccg ggtaggtcct
     6661 gaatatgaat gttcggattt tttttcaacg atccttcttt tttttctact gttacgcccg
     6721 gccaattccc tacatattga ttcgaaccag tcaagagatt gaacaagcta gttttcccgc
     6781 tgtttggatt tccgactaac gcgatattca ttctttttcc tccctttgta tcaagattag
     6841 ttcggcctct gactttcgta acgtcagttc ataccctcgc actgtcagtt cgattggatc
     6901 tcccagaggg gctagttttc ggataactat ttttacattt cgcgtcaatc ccatatccat
     6961 taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg acgatcccag tctctcctgc
     7021 ttttaattga tcaagagaag tccagctttc agaggaagca gtctttttat tgacaaagat
     7081 ttgacctagt atttcccgac ttactgccac tcgatgactt tttaccagta aaatggcatt
     7141 gttgcctgat aaattgacga cgacgatttt acttccggca acgatcccga tattttgcaa
     7201 atggcgtttt gttttttctt ctgtttcgat tcgttcgact tgataaacga aattctgctt
     7261 tgcctgcgct aaggtctgca tattgattcc tctcttgtga aataaatcat gtattaaaat
     7321 cattcattat atgttctaat tttcttacgt gttacgcaaa taaatgagaa tcattctcac
     7381 atagaatact ctcggtaatt gagaatgtca attatacttg tgatattatg agcgaatctt
     7441 tagtattgat agataaaaat gagaaaaaaa tatttcttca tagttttcca caattttttc
     7501 tctattaaat ttgctatttt cccacacgat acttgttttc agctcttttt tcaaaaacac
     7561 aaaacttagt attccacagt ttccacaaca caatatgtag tgtttgttgt ttgacttttt
     7621 tactaagagt tttatactat ctattataga taataagaat gtgttagagg aggcactcac
     7681 catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa tgtaagatgg tcaaacggtt
     7741 tttaacagaa aatcaaattg cttttgaaga agtcaatatc gatgaacagc ctgaagcagt
     7801 agactggttg aaagcacaag gattccaaag tgttcctgtc attacttctg atgcagaaac
     7861 agttatcgga ttccgtcctg atcagttgcg taaacttgcc agctaacatg actaaaagaa
     7921 tcaaaacgtg atacatggat ttgaagggct tgagacagca ccagtttttg tcgcaaactt
     7981 ccaaatcctt ttttaaagct taaaaacaat gcaatgattt gcaatcaagc atcatcaaat
     8041 acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt tacaagatgt cagttatttc
     8101 aagctgaata atgaaatcaa tcggccagtc aatggtcaaa tccctttgaa taaggataaa
     8161 gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa atacgatgac ttttccatct
     8221 attatggaaa aaatcaatta cttgatcgat caagaatata tagaagcaga attcattcaa
     8281 ttgtattcac catcatttat tgaaaagcta tatcaatttt tggacgagca acatttttct
     8341 ttcaaatctt ttatggctgc ttacaaattt tattctcaat atgcgttgaa aaccaacgac
     8401 ggttccgctt atctggaaac ttatgaagat cgagtagcct tcaatgcgct ttactttgcg
     8461 aacggggatg aagaattagc acttgctctt gcagacgaaa tgatccatca acgatatcag
     8521 ccagctacac cttctttctt gaatgctgga cgtaaacgtc ggggcgaatt ggtgtcttgt
     8581 ttcttgactc aagtcactga cgatatgaac tctatcgggc gctcaatcaa ctctgctttg
     8641 caattgtccc gtattggtgg cggcgtaggg attactttat caaatcttcg tgaagccggc
     8701 gctcctatca aaggatatga gggtgctgca agtggtgtcg ttccagtcat gaaattattc
     8761 gaagatagtt tcagctattc taatcaatta ggtcagcgtc aaggagctgg cgtggtttat
     8821 ttgaacgttt tccatccaga cattattgct ttcctttcag caaaaaaaga aaatgcagat
     8881 gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg tacctgataa attttatgaa
     8941 ttgacacgta aaaacgaaga tatgtattta tttagtccat atagtgtcga aaaagaatat
     9001 ggtgtcccat tctcttatgt aaatattaca gctgagtatg atcatctagt tgcaaatcca
     9061 aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa atgaaatctc aaaattacaa
     9121 caagaatctg gctatcctta cgtaatcaat attgatacag cgaaccgcga gaatccaatc
     9181 gatggcaaga tcatcatgag taatttatgt tcagagattt tacaagttca aacgccttct
     9241 gtgattaacg gcaaacagga atatgaagta ttaggaacag atatctcatg taacttaggc
     9301 tcgacaaata tcgtgaattt gatgcaaagc cctaactttg gtcaatctgt gcgtacgatg
     9361 actcgtgcat tgacatttat tacagatgca tctgatatcg atgtcgtacc accgatccaa
     9421 aacggaaata agctgaatca tacgattgga ttaggtgcca tgggcttaca cacttatctt
     9481 gcaaaagaac aaatggaata tggctcagag gattcattag actttacaaa tatttacttc
     9541 atgctgttga attattggac acttgttgaa agcaacaata tcgctcgtga aagaaaacaa
     9601 gttttccata attttgaaaa atcagcttat gctgacggca cttatttcga aaaatacgta
     9661 actggagaat tccagccaaa atcagaaaaa gtcaaagcat tgtttgaagg catttttatc
     9721 ccaactgctg aagattggaa tgctttgaaa caagcagtaa tgaaagatgg actgtatcat
     9781 caaaatcgct tggcagtagc accaaatggc tcaatttcat atatcaacga tacgagtgca
     9841 agtattcatc ctatcactcg catgatcgaa gaacgccaag agaagaaaat cggtaaaatt
     9901 tattacccag cgccttatct atccaatgag acgattccgt attacacttc tgcttatgat
     9961 atggacatgc gtaaagtaat cgatgtttat gcaacggcac aacaacacgt cgatcaaggc
    10021 atgagtttga ctttattcat gcgttctgaa atcccagaag gcatttatga atggaagaca
    10081 acaacgaagc aaacgacacg tgatttgaat attttaagac attacgcttt ccacaaagga
    10141 atcaaatcca tttattacgt acgtaccttt actgatgatg cagaagaaat cggaagcaat
    10201 caatgtgaaa gctgcgtgat ctaatatcat agatagattc gcttattcat attttaatta
    10261 aaggagcatt ctcatgtcag aaacatatta tgaagcaata aactggaatg aaattgaaga
    10321 tatcattgat aaatccactt gggagaagct gacagagcaa ttttggctag atacacgtat
    10381 cccactttca aatgacctag atgattggcg tacattgtct caattggaaa aagatacagt
    10441 aggacatgta tttggcggtt tgacactgct agatactgtc caatctgaaa gtggcatgga
    10501 tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc gttttgaaca atattcaatt
    10561 catggaatcc gttcatgcca aaagttattc ttctattttt agtacactga atacgaaaaa
    10621 agaaatcgaa gaaatttttg actggacaaa tacgaatcct tatctgcaaa aaaaagctga
    10681 gcgtatcaat gaaatctaca aacacggtac accgctagaa aagaaaattg ccagcgtctt
    10741 tttagaaaca ttcttgttct attcaggttt ttatactcct ctttattatt taggaaacaa
    10801 caaattggct aacgtagcag agatcatcaa actaatcatc cgagatgaat ctgtacatgg
    10861 aacctacatc ggttacaaat tccaattagg attcaacgag ttacctgaag cagaacaaga
    10921 aacgttaaaa gactggatgt acaatcttct ttatgagctt tacgaaaacg aagaacgtta
    10981 tacagaagaa ttatacgatc caatcggctg gacagaagaa gtcaagacat tcctacgcta
    11041 taatgccaac aaagcattga tgaacctagg gatggatcca ctctttccag atactgccaa
    11101 tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc acaagcaacc atgacttctt
    11161 ctcacaagtc ggaaacggct atttgttagg tcatgtagaa gcgatgaaag acgacgatta
    11221 tttgattgga ttggaataag gatttatttt aattcaaaaa tttttcgaaa aataaaaaga
    11281 gtttagcgta cagatatttt aaatgtacac tgaactcttt tttatgctta ttcacttgtt
    11341 tcttccagca cttttggact gtctaacttt tccgaaacat gttccattct tctcaataaa
    11401 tagattttcc ggatatttaa tattatcgtc ttaatcactg catagacagg tatgcaaatc
    11461 agcatgccta atattcctgc gacacttcct gctccaatca ataccaagat gatcgtcaaa
    11521 ggatggatat tcattgattt cccaaataac aacggcttga tcaaatttcc atctaattgt
    11581 tggatcacta aaatcgacaa cgccatatac aaagcttgaa atggagagat aaacaaaccg
    11641 acaatgattg ctggtaccgc tccaataaaa gggccgacat acgggataat attcgtgatt
    11701 ccgcaaatga ccgcaagcaa caagctataa ggctgatcga atattctcat tgccaaaaag
    11761 ctcattacac caataatcaa agcatctaag atcgtactgc tgatataggc agataatgtt
    11821 tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa tcgctttcgg aaagaagtga
    11881 gacaacgcat caataaattt gtgcccatcc ttgaacataa atagcaaaat aaatggaacg
    11941 gtaaataaca aaataaaaaa ttgcatcata aatgaaatga tttttgagac acttgcagat
    12001 aaactgacta atatgatatt gaacaaatta ctaagagata aatttgctga tgctaattgt
    12061 tcttccaaat tgaaattttt aaactcttcc cgctgcgcca attcatttaa ccatttgctt
    12121 gtttcatctg catacattgg caagctctgg gtcaattgaa ttgtctgttc cattaactga
    12181 ggcactacat tcatgacagt taaaacaact aaaatgatta cgaccaaaaa cgtcaataaa
    12241 aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa caacgattgg atcgaacata
    12301 taatagataa aaccagcaac aagcaatggt aaaaaaattg ccgaaagcat tttcaatatt
    12361 ggactaaaaa tattcggcat ttgtaaaata aagtacacgc cgatgatcgt gagtactagc
    12421 tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg attgcataca tctcctccaa
    12481 ggtcctttga tacttctatt ctatcattta acaaagagtt acgcgctgag attttcattt
    12541 gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt agacgagtac ttaaacaaaa
    12601 acacggtttg gagtagtgac aaaaattata ctgcagtccc tttttccaaa taaacggtgt
    12661 tcaaaagctt gcatcttcgt aataagccca gccaaacgaa aaatataagg aactattttt
    12721 atttggctgg gcttattact tgatgtagga catctatttt acaacctcag atcatttatt
    12781 gcgcaatact gactaaatgc aactttgtga tatttttgtg tacggacaac tcctcgatca
    12841 catcggcata agtgagccct tttggaagat caatcgtata gatatttttg tacactcggt
    12901 agtcatcaac gaattttacg tcaaaattca catcttcgat tacgatattt ttctcttcaa
    12961 aataatcggt aagaaaatct ttggtttctt ttctatggat aaattggatt tctaactttt
    13021 tagtcgtagg tacatggatc acgcgtttca ctactgtgag tgcaatagca atcccgataa
    13081 aactgatgat cgcaatggaa tagtaaccca tgccgatggc gatccctaat ccagcaattg
    13141 cccataaaga agcggcagtc gtaagtcccg tcaccgattg tttcgtgacg atgatcgttc
    13201 ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat cagccttgct tcatctgaac
    13261 gaatcgttcc agcaagctgt ggatactcta aagcatctct taatgcacca ctagcgatct
    13321 caacttggat caatgcaatg atacatgctc ccatacaaac taaaatatgc gtacgcatac
    13381 ctgctggacg atttttatat tgtcgttcaa aaccgattgc tccgccaaat agcatagcga
    13441 tccctaaacg taaaataatc tctggaattg tcaataccat atcattcatc taaacaccct
    13501 ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa agtgcaattt ttacctctta
    13561 cgaaaaaagg actgtgacaa aatttttgtc atagtccttt ttatgaataa acggtgttca
    13621 atcagctgac cctcggtatt actcaacaaa cggcaaaata tggggagcta tttttccttt
    13681 gtcttctcta atactcaggt caaaacgctg atttcacaac ctctttagcc tactattgaa
    13741 aattacaact tacttgctgc ttcttcatcg atgatcacaa caacattgtc gtgattttgc
    13801 aatacacttg ctggcaaatg attcgttaca ggtccttcaa tcatcccttt gattgcatca
    13861 gctttgcttt cgccaaatgc catcaagacg atttctttac ttttcataat tgaaccgatt
    13921 cccattgaaa cagcttttgt tggtacatct tctgctttat cgaagaatcg tttgtttgca
    13981 ttgattgttg attctgttaa gtcaactact gaagtcgttc cgtcaaatga agcaccaggt
    14041 tcattgaaac cgatatgtcc attttgcccg attcctaaga tttggatatc gattggatgt
    14101 gcatcgatga tttgatcata ctttttgcat gctgcttcca gatcttctgc ttttccatct
    14161 ggtacaaacg tttctttgaa tggtttttta tcaaataatt ggacatccat gaaatgacgg
    14221 tagctttgtt catctgaacc gcctagtcca acgtactcat ctaagtttac agaagtcatt
    14281 tcactgaaat ccaaatcgct tgaagtcatt tctttatata aagtaactgg tgtgcttcct
    14341 gttgccaatc ctaatacttt tgcacctttg ttcatacctt ctttgatgat ttcaaatgct
    14401 ttttttccgc cttcttcagc gttttttaca cgaatgattt ccatagtgat tgctccttta
    14461 tattttggta tagcccaatt atagcattct ttttttcttt ttacaataat tagtatagac
    14521 caaattgcat ttttttcatt ttcttgacaa taaataggaa tccgtgttag gtttcataag
    14581 atggttcaat caaacaatcc atgttgcatg aaaaccaagc aagtgattca ctgtggacgc
    14641 tttatgtctg cagttttttt atgaaaaagg agttattatg agtatactga cattaaacaa
    14701 cattacccag caatttggcg acaaaatcct ctatgaaggt gtcgatctgc aattaaatgc
    14761 tggcgaacat cttgggctga ttggacaaaa cggagccggt aaaagtacat tgattaaaat
    14821 catcactggt gagatcttac cagatgacgg acagatccat tggcaaaaaa atattcacaa
    14881 aggttacctc gatcaatatg tggaagtcga tgaaacatta acaatcgaag aatttctaaa
    14941 aactgcgtac gcaaaagaat acgaaaagga agaaaaaatt gcttttcttt accaaacata
    15001 tagcgagacc ttcgatgatt ccttgctgga aaaagctggg aaactccaaa cggaattaga
    15061 ccaaggagtg ttttatcaaa tcgacacctt agttgctgag atgagcagcg ggttggggat
    15121 cgatgtctta ggtttagatt cactgttgaa aaatctaagt ggtggacaac gttcaaaggt
    15181 gattttagca aaactacttt tagaaaaccc agatgttctg atcttagatg aaccaaccaa
    15241 tcacttagat gatcagcata tccaatggct gacgcagttt cttcaggatt ttgacggtgc
    15301 gtatatcgtg atttcccatg accaagaatt tcttgatcag atcaccaccc atatcgcaga
    15361 catcgagttt ggaaagatta ctaagtatac tggccatcta aaacaagcat tgaaacaaaa
    15421 ggaacaaaat cgcgaaagct atttgcgcca atatcatgct caacaaaaac aaatcgaaaa
    15481 gaccgaagct tatattcgaa aatacaaagc cggttcccga tcaacgatgg caaaaagccg
    15541 acaaaaacaa ttagataaaa tcgaacggct gacgcctcca gcttcagcaa gtaaagctgt
    15601 ctttgatttt ccattctcgc ctattgtcac gacattagca gtggaaacaa ctgatttagt
    15661 catcggatat gatcgaccgc tacttgcacc catcaatttg accatccgct ttggtgaaaa
    15721 tattgccatt cgaggcttca acgggattgg aaaatctact ttattaaaaa cactgatcgg
    15781 tgagattgaa aaaataagtg gcgatttcca cttcccagat aacacaaaaa tcaattactt
    15841 ttcacaagat ctgtactggg aaaatccatt agaaacacca ctacaatatt taagcagtca
    15901 atttccaaaa gcgactatca aagaattacg tcgccaacta gctaaagcag ggttagttaa
    15961 tcaattagca agtgaacctc tcactacatt aagtggtggg gaacaaacta aggtgaaact
    16021 tgcacagttg acaatgaacc aaggtaattt actgattctc gatgaaccga cgaaccatat
    16081 cgatcaagaa acgaaagaaa gcttacaaga cgggatacag aaatttccag gaacagtaat
    16141 catcgtctct catgaacaag aattttatca agatcttgtg caacgagtca ttgagattga
    16201 accaaaataa acgtttgatt gaatagttga aaaaaaggag ctgtgacaaa agttttgtca
    16261 caactccttc ttctgaataa atggtggcca attagctgac cttcggtatt agctcaaaaa
    16321 acggcaaaat atgaggagct atttttattt ggctattctt attacttgat gcagaacagc
    16381 ttttcacaac ctcttttcgt ctatttttta ttttcgagat ttctctttcc tttaaaaaca
    16441 actgtttgaa agaagaacgc acatccttga aaaacaagcc cgctaaccgt tacacctaac
    16501 cagccatact gctgccacat tgtcgtccct agcaatgaac cagccgcacc tccaataaag
    16561 tacataaaca taaataca
//
LOCUS       DADVXV010000064        16540 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.065, whole genome shotgun sequence.
ACCESSION   DADVXV010000064 DADVXV010000000
VERSION     DADVXV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.065"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..313
                     /locus_tag="KB969_002017"
     CDS             <1..313
                     /locus_tag="KB969_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869984.1"
                     /translation="INAPLIPTALSFSVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFS
                     TGEVSVSLPPQVNDINFNINARNVLVEEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEK
                     N"
     gene            327..728
                     /locus_tag="KB969_002018"
     CDS             327..728
                     /locus_tag="KB969_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869985.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            730..1101
                     /locus_tag="KB969_002019"
     CDS             730..1101
                     /locus_tag="KB969_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869986.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1137..1436)
                     /locus_tag="KB969_002020"
     CDS             complement(1137..1436)
                     /locus_tag="KB969_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869987.1"
                     /translation="MLFNETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(1442..1672)
                     /locus_tag="KB969_002021"
     CDS             complement(1442..1672)
                     /locus_tag="KB969_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6869988.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(2108..2674)
                     /locus_tag="KB969_002022"
     CDS             complement(2108..2674)
                     /locus_tag="KB969_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBB6869989.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(2674..3630)
                     /locus_tag="KB969_002023"
     CDS             complement(2674..3630)
                     /locus_tag="KB969_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBB6869990.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(3630..4286)
                     /locus_tag="KB969_002024"
     CDS             complement(3630..4286)
                     /locus_tag="KB969_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBB6869991.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            4656..6674
                     /locus_tag="KB969_002025"
     CDS             4656..6674
                     /locus_tag="KB969_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6869992.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    6744..6950
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7101..9515
                     /locus_tag="KB969_002026"
     CDS             7101..9515
                     /locus_tag="KB969_002026"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBB6869993.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            9863..11416
                     /locus_tag="KB969_002027"
     CDS             9863..11416
                     /locus_tag="KB969_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBB6869994.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(11797..13581)
                     /locus_tag="KB969_002028"
     CDS             complement(11797..13581)
                     /locus_tag="KB969_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869995.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(13596..15317)
                     /locus_tag="KB969_002029"
     CDS             complement(13596..15317)
                     /locus_tag="KB969_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6869996.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            15417..16178
                     /locus_tag="KB969_002030"
     CDS             15417..16178
                     /locus_tag="KB969_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6869997.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         5437 a         2966 c         3229 g         4908 t
ORIGIN      
        1 tattaatgcg cctttaattc ctactgcttt atcattttct gtaacagctg tggtgtctga
       61 gatagaggat acagaaaaga taaaaatagt agaaattgaa gttttaaaca agaatgaaaa
      121 acaaattttt tctacgggtg aagtatcggt aagcttgcct cctcaagtta acgatataaa
      181 ctttaatata aacgccagaa atgtcttggt tgaagaagca ggagagcatt atgctgttgt
      241 taaatttaat ggaactgaga ttggaaggca aatctttgat atcaaggtca acaaaccagt
      301 ggaaaaaaat taaggagacg atacggatgc ttgatatagt accatcaaat acacatcgga
      361 gtggtagctt aataaatttt gctgcgattt ttgcttgcgc atcggtaatt ctagcatctc
      421 cagttgttgt ggatgcaagt tctactccga aaactaaaaa tgataatcaa cttgtaatta
      481 ctacaaaaaa tgagattaac acaatttcaa gtaatgatgg caaaattttt gatgtgataa
      541 atacggtttt aaaaagaaaa gctgaaatca atataaaata tgatgaagat ttaaacttgt
      601 atttctttgt tatcaaaaca acatctgaat tgttttcctc agattacgat gttttggata
      661 ctctcgataa tgtattatct gactataaat atatggggaa atctgtagta gcaactttgg
      721 gggaataaaa tgtttgactt taatgaatat ttatctattt ccaaacaaat tgaatcagat
      781 gataaatata attctaaaga atcttataga agaactgctg tttcaagagc atactacagt
      841 gcttttaaaa aatctgatga gtatttgaaa gaaaattatg atattattta taatggaagt
      901 agcggaaaag gaagccacca aaccgtttgg aatttgtttt caacagttaa ggaattgaat
      961 accttaggaa tacataatag tgggtataga atgttagaga aaagaaaatg tgctgactat
     1021 attcctaatg aaaccattac gaaaacagat atggcgctga tgaatcgaga agcagaaaaa
     1081 ataataaaca aactcaccta atgaatttca agcgagtttg tttgttattt ttttatttaa
     1141 tctttgtatc tttctggatc aacgaaagta tactttatat agtcataacg ccgatgatcg
     1201 ctacgtgcgt ccggcacgtc agtcacgata tcaaacaaaa agtatacacc cttcttcatt
     1261 ctagttttcg cagcaggaat tttgaaatag ttcttattag aatagtagag attgattaat
     1321 aagctatctt cgattgctaa aaagaaaact tctgaattcc atactttata aaaatctttg
     1381 ataaatctat tcgaagggtc aaatttaaac cataattgtg tctcattaaa aagcataacc
     1441 attactccga tctgttttta aaattagttt ctacctctaa tatatatcga gtttttattt
     1501 tgccttcaga gaatactgtt tctttttttg cagttacagg ttgtttattt tcggaaaaag
     1561 ctaatatagc taagattgaa acatccatct ggaatttatc ttttttactg ctttgatcat
     1621 aaaagtctgc atattcatca ctgatatttt ttctaataaa ttcttccatc ataaaaatca
     1681 cctcaaaacg attatacgaa cttacgttct tgttgtaaag cgatatttga ggggcaaaaa
     1741 aggggcataa tttgactgat attaagttag ctattgatat atgaatgaca tacaaaaata
     1801 taaaatcttt taaaaatgct tatatatcaa tgtttttgcc attcttttat atatctgtta
     1861 tatgtcaaaa aaatgtgttc aatttcaatt tgtatttgaa taaagaggtt gtgaaaaagc
     1921 tgtcctgcat caagtaataa gaacagccaa tcaaaaacag cttctcatgt ttttgatttg
     1981 gttggactta ttaccgcaga tataagcttt tgagcaccgt gaataaagag gttatgaaat
     2041 caacgctcta acctgagtat tagagaaaaa aacgcaaaac atatcattta tgttttgcgt
     2101 tttttattta tctttttttc tcaatacaat ataaaatagg cggctggttc ttttggttga
     2161 taaaccgata attcagcaca ttatatgttt cctgtggcag tttggaacaa aaagaatcaa
     2221 ccatatccag ttctttttct ccaccttcat gaccatagta gacgacaagg atcaatcgtc
     2281 cgcgaggcac aagtcgtttc aatatttctt ccatagctgt gcgtgtagtc tctggcatag
     2341 tgatgattgc tttatcactt tttgggagat accctagatt gaaaatccct gctttgagat
     2401 tttgttgttc agctatcact tctcctaacg tttcgtggcc ttgtagaaac aatgagacac
     2461 gttcttctaa ctgacgctgt tctagccttt cacgagtagc atcgattgct tgttgctgga
     2521 tatcaaaact atagacatga ccagtttttc cgatgtgttc tgctagaaaa accgtatcgt
     2581 ggccattgcc catcgttgca tctacgacgt gatcccctgg ttgcaagatt tcttgcagta
     2641 atgtatggct gaaatgcaaa gcagtttgca acatcagacg ctcacctttt tccgtacatc
     2701 atattttcct tggaagctat ctctgcgaag aagttcttca tcaattgcat tcaagacttc
     2761 ccattttttc aagctccaca ttggtccaat caaggaatcc cacggcgcat cccctgtcaa
     2821 acgatggatg atgatctctt ttggtatcat ttccagctgg tcgcaaatga cattgacata
     2881 gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag tcccgcaaca ttctcgtttt
     2941 gcgcatcaga tgcatcaaat ggagcttgat tccttggata tctgaatcta aaatggtgcg
     3001 tctgacattt tctttcatca tttctaaact ttcgcctggt aatccgttga tcaaatgcgt
     3061 acaaacacgg atattatgtt tgcgtaattt agccacgcca tctaaataag tttgataatc
     3121 atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt gtttgcaatc caagttctac
     3181 ccataaatac atccgctcgt tcagttcagc aaggtaatca actacttcat ctggcagaca
     3241 atccggtcgt gtaccgactg ataatcctac gacacctggt aaattgacta cttgctcaaa
     3301 tcgttctttg attatttcaa ctggcgcatg ggtgtttgta aaattttgga aataaacgat
     3361 gtattgttgg acatgaggcc atttttgatg catcatgtcg atttctttct ggaattggat
     3421 tggaagaggg tcttcaggtg caacgatcat gtctcccgaa ccagatacac tgcaaaaagt
     3481 acaaccgcca tgggcaacag tcccatctcg attcggacag tcaaatcctc catcgatcgg
     3541 caccttgaaa attttcccgc caaactcatt tcgtaaagcg taattccaag aatgatatct
     3601 tttatttcct tctgaataag gaaaagtcat taaaagtcct tctttctgta agagttatct
     3661 atttgttttc ttttttctct atacactgga taagtcaggc acagccaaga aagactgagt
     3721 aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca gataaatgcg gcttatcccg
     3781 acacttacta taataaacat catcagcaat tgaagcaatg tgcgtaaggt tcttttttga
     3841 acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa tcatactgcc tgctgcatgt
     3901 ccactaggga aactgtaact tgtttcaact actaagtgcg ccaatgaagg acgctctcgc
     3961 atgaaaaata gtttgatcac cgggttgatg attccagcaa ttacaataaa tccagaaacg
     4021 aaccaaaatg tttctgccct ttttttctta taccacatcc ataaagccgc acaagcaaat
     4081 aaaatgatga cggtaagagg attaccgaat ttagtcataa agagttggta gctgttcaga
     4141 tcaggataag aagctctgac aatgcctgta aaccactgat cgaaaccaga aagccacgac
     4201 agatggaact ttacgatcca gcccaaaatg aaaaacagga caagaaagaa gctaccagcc
     4261 acctgaaatg atgttttata tttcatacaa ttcctccttt gaagcaatga cttattatag
     4321 catttttggt ccagcgaaaa aaacggtaaa gagataaaac caatgtatga ttcctctttg
     4381 aataaccaat attcttataa aaaaaataac tgtaatcgga aagacatttt ttggtaatgc
     4441 aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa tccttttaaa caagaacgta
     4501 gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt acggtaaatt acaatatgat
     4561 tacaaaaaac aacaaagctc ttaaataact tttaataaat attaagagaa gttataatta
     4621 ttaataatag ataaattgaa gttggaggat agaagatgga aaacattgca agaaaagaac
     4681 ggagacgttt agaacagacc aaacgttttc gaaaagcaaa acgaggggca gcaatcgtgg
     4741 gaactgcgat ggtaggctgt tctgtcgctg ccccattagt acagccggtt cctgttcaag
     4801 cggatgaaac acctgttcag ttcggcgcaa gaatcaatac agcggcattt atcacagaaa
     4861 ttgctactta tgctcaacca atcgctcaag ccaacgatct atatgcatca gtgatgatcg
     4921 cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt atctcaagca ccttattata
     4981 atctttttgg gataaaaggc agctatcaag gacaaaccgt ctacatggat acgcttgaat
     5041 ttttaaataa tcaatgggta aataaaaagg agcctttccg acaatatcct tcttttgctg
     5101 aatctttcaa tgacaatgcc tatgtactta gaaatacttc atttggcaac ggttattact
     5161 atgccggtac ttggaagagc aacacgaaat cctatacaga tgcgacagct tgtttgacag
     5221 ggcgttatgc gactgatcct ggttacgcag gcaaattaaa taatatcatc gcaacttacg
     5281 gattgaccca atatgataca ccagctagcg gaaacgcagg cggtggagcg actacaggtg
     5341 gcaataatac tggaagtgca ggtagtactg gcggttcaag caattctggt aatacaaact
     5401 caggttcagc aacttcgacc acttatactg tccaatctgg tgattctgtt tggggaatct
     5461 caaataaatt cggtatcaca atggatcaat tgatccaatg gaacaacatc caaaacaatt
     5521 tcatttatcc aggacaaaaa ctgacaatca aaggtagcca ggaaaatggc tcttcgacga
     5581 ataattccgg taacaatacc aattcttcag gaaatgctgg tacatcaaac ggaggacaaa
     5641 caactggtgc gaaatacact gttcaatctg gtgattctgt ttggaagatc tcaaatgatc
     5701 acggaattac gatggctcaa ttgattgaat ggaacaatat caagaacaat ttcgtttatc
     5761 caggacaaca gctaatcgta tcaaatggcg gttcttctaa tgctggagca aatactggct
     5821 caaatactgg gaatacaagt ggctctagtt cgtccagctc aagttcttct aatacagctt
     5881 caggaacgaa atatacagtt aaagccggag actctgtttg gagcgtctca aataaatacg
     5941 gaattacgat ggctcagcta atccaatgga acaatatcca aaataacttt atctacccag
     6001 gacaacaact gactgtttca aacagtggat caacaaacag cacgtcaggt aatacaggtt
     6061 cgtcaaccaa tacaaataac agcagttcag ttaatactgg cagcagttcg tctcaaggca
     6121 cttataccgt gaaagcaggt gaatctgttt ggagcgtggc aaataaaaac ggcatcacga
     6181 tggatcagtt aatcgaatgg aataatatca aaaacaactt catttatcca ggacagcaat
     6241 tgatcgttaa aggtggaact tcggcaaata caaatacagg ttcaactact tctgcagcga
     6301 aaccaaatac accgaatacg tctgctacga caagtacatc atccactggt aatacgatgt
     6361 ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa caaacatcat atcacgatgg
     6421 atcagttaat cgaatggaat aatatcaaaa ataatttcat ctatccagga cagcaagtga
     6481 ttgtgaagaa aggttcatct caatcaacaa accaacaatc agttactggt tcgaaaacct
     6541 atactgtgaa atctggagaa tctgtttgga gtgttgctga cagtcatgga attacaatgg
     6601 ctcaactaat cgaatggaac aatattaaga acaactttat ttatccaggt caaacgttga
     6661 ttgtagctaa ataaaatagc tgttcgaaga aataacgatt gaattccaca aaaatatttg
     6721 ttactataag gctacttaaa tatgacaaca cttgaaaagg aagtagtaaa aagactgaag
     6781 tttcagagag cgcatggctg gtgagaatgt gcacggatgc ttttgaactc gcctttgagt
     6841 tgcccttgct gaatacccga gtaagcaagc ggcggtgacg gccgttacaa cgttcgaggc
     6901 cttttcacta aggtaaaatt aggtggtacc gcgtagatta cgtcctataa aaagagcaat
     6961 ctttttatag gattttttta tttcttttgt gaagtttgag aaaacaaagc aaaaggaaat
     7021 aaaaataaac agattctgcc ggttttttcg ttatatttat aatagaaaca agtgttttca
     7081 atagaacagg aggacagcaa atgagttaca atcataaaga aattgagaaa aaatggcaaa
     7141 aatactgggc aaaaacgaat actttcaaca cccatgatga tcctgaaaag ccaaaatttt
     7201 acgcactgga tatgtttccc tatccatccg gtcaagggct acatgtaggg catcctgaag
     7261 gttatacggc aacggatatc ctttcacgtg tgaaaagaag tcaaggatac aacgtgctgc
     7321 atccaatggg gtgggatgca ttcggtctgc ctgctgaaca atatgcgcta gatacaggaa
     7381 acgatccagc tgagtttacc caaaaaaata tcgaaacatt ccgacgccaa atcaattctt
     7441 taggatttag ttatgactgg aatcgcgaag tgaatacaac tgatccggag tattataaat
     7501 ggacacaatg gatctttacg aagctttatg aaaaaggtct agcttatgaa gcagaagtag
     7561 cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa tgaagaagtg atcgatggga
     7621 aaagtgaacg tggtggctat gatgtagtca gaaaaccaat gcgccaatgg atgctgaaaa
     7681 tcactgctta tgctgatcgc ttattggatg atctagaatt agttgattgg ccagaaagca
     7741 ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg agcaaatatt gaatttaaag
     7801 tggctggtac ggataaatcc tataccgtat ttacgacacg accagatact ctattcggtg
     7861 caacttactc ggttcttgca cctgaactag atcttgttag agaaattacg acccctgaac
     7921 aaaaagctgc tgtagaagct tatatcgaag agacagctaa aaaatcagat ctaaagagaa
     7981 cggatcttgc aaaagaaaaa acaggagtat ttactggtgc ttatgcaatc aatccagtta
     8041 atggcaagga aatcccaatc tggatcgccg attatgtatt atcttcatac ggcacaggag
     8101 ccatcatggc tgttccagca catgatgaac gtgactttga attcgctcaa actttcggac
     8161 tagaaattct tccagttatc gaaggtggag atgttgaaaa agctgcttac acagaagatg
     8221 gtacgcacat caactctgaa tttctagacg gcatgaacaa acaagaagca atcgataaaa
     8281 tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga agtcagctat cgcttacgtg
     8341 actggctatt ctcccgtcaa cgttactggg gtgaaccaat cccaatcatc cattgggagg
     8401 acggaacagt cacagctgtc ccagaagaag agctaccatt acggttgcct aagacaaaaa
     8461 acatcaagcc aagcggtact ggagaatctc cattagcaaa tatcgaggag tgggtcaatg
     8521 tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac gaatacaatg ccacaatggg
     8581 caggaagctc atggtattac ctgcgttata tcgaccctca taacaaaaaa gaactagcag
     8641 attatgaaaa gttgaagcgt tggctaccag ttgacatcta cattggtgga gcagaacatg
     8701 cggtacttca tttactatat gcacgattct ggcataaatt cttatacgat atcggtgttg
     8761 ttcctacaaa agaaccattc caaaaactat acaatcaagg aatgatctta ggcgaaaaca
     8821 acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc tgatgatgtg gtcgaaactt
     8881 acggtgcaga tacactgcgc atgtacgaaa tgttcatggg gccattagat gcttcgattg
     8941 cttggagcga aaatggctta gaaggaagcc gtaaattctt ggatcgtgta tggcgtttga
     9001 tcgttgatga gaacaataaa atgcgtgacc gtatcactac attgaatgat ggcaagcttg
     9061 ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga ctatgaaaat cttcatttca
     9121 atacagcaat ctcccaattg atggtcttta tcaatgaagc ctataaagtg gacgctctgc
     9181 cttatgaata tatcgaagga tttgttcaac tactcgcacc gattgctcct cacatgggtg
     9241 aagaactatg ggcaatcctt ggaaatgatg gtggtatttc ttacgcacca tggccaacat
     9301 acgatgaagc agcacttgtt gaagacgaag tagaagttgt tttccaagta aacggtaaag
     9361 ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga tgagctagaa aaagcagcat
     9421 tagccaatga aatagtgcaa gaatatattg aaggcaaaac agtcagaaaa gttattgcgg
     9481 taccaaacaa gttagtcaat atcgttgcta attaattggc tctttgtcaa taaggactga
     9541 tgagttgtgc aaaatcaaat ctgggccaga atgaacttca ttctgtctca gattttttgt
     9601 tatttcaaat tgattaattg attgatcaaa aaggttttga ttttcatgtt ctcaaacacg
     9661 ttcaatgtct ttttcttctg aatggtcttg taagagatct ctgtaatcat caaatttttg
     9721 tctattaatc ttagtatttt ttgatgtata aactacctga aattgagagt acataccaaa
     9781 ttcataaatt ttttattagt gggactagtg attgtatgga ttttgacgca taatgaatga
     9841 agtatgagaa aaggagagac aaatggatca agaactattt attatcgaag tattatcagc
     9901 taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa agaataatgt tcaagctttt
     9961 aagcttagta tttttctctg gtttgctttt tttcggagct gtatcgttcc tatatcgcca
    10021 tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa ttaaataatt tgtatcactt
    10081 ttcgtgggga gttggcggaa taacaattgt tgtgcttatt gtttttcttc tacttatttg
    10141 gctccgttac catcaattgt cgcgtcattt cgatcaatgg cttagtcaaa gagcacaaca
    10201 gtttttacat aataaaccaa cttctcaaga tgatgactat ctttattttg agaagacttc
    10261 gacgagtcaa gcttttcgga tacaaaaaag tgattgccag ttattgctga gatcacttga
    10321 tgatttacct atctacttag gcgaaagcaa atcaaaattc ggaatgaaca cattccatat
    10381 ttttttacta gaaaacgaac ccagatggga aaaaagccag tcttcgcctg gtggatacct
    10441 gacaactaag atgagtacat tagtcactgg ttttttcctc attcttttag ctggaacaat
    10501 ctattatggg agatacactc agccaaaaat gtcttctcat ataaatgctg cttctcacat
    10561 gacaatgaac tcaactaacg atacgcatat acaaaagaca aatgaagggt tgttagctga
    10621 tcctaagcaa aaggtaaatt tgacaacaca aaagataaat gatctcaaac ttgatacaga
    10681 gacgcactct ctctatatga caacagatag tggtgctaat tgggtatttg tgccgattga
    10741 ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg gggctgattc ctgaaggtta
    10801 ttggatggac aacacatatg atatttccgc cgatttctca tggtttatct attcttctgg
    10861 ggatgatgta cgtctgctga cttcaagaga taatggtaaa acatggcaaa cgtctattat
    10921 cacccaatca gttcagccga tacgttatcg aaaagcggta ttttatggca acgatggtct
    10981 atttatctgt acatcagcca gtgggatgtc tgcagaaact ttgtacattt acactactat
    11041 ggatggcgga atcacttgga taaaaagtgg aagtacaatg atcaatcagc cagtacaaaa
    11101 tgtcagcttc gttacaactt ctttaggttt tgtttcgaca cgtgaaagtt tgttttatac
    11161 aaacaacgga ggacgctcat tcaaagaatc agttctgtcg attccggaaa actatcagac
    11221 aggggggata gatctttttc aatcaccaaa tgaagttact caaataagcg cgaatacgtt
    11281 agagacaaaa ttttatttgt tgaaaaaagg accaatcgat gcagggaaaa tgtttgcctg
    11341 cctcttccgt tcaactgata acggggaaac atggcaattc gttcagcaac tatcgcaagt
    11401 agaacaagga gattaaagaa gagagattgt gagcctgacg ttcagcaccg agtcacaaga
    11461 aacaaattca aaaaacagct tctcatattt gttgaatagt gtaactcgtg attcggagtt
    11521 gacaagagca acaagaagcg attttgaagt atagcttctc gtattttaca agatcgtgtc
    11581 ttattgccga taggttgtct cttgaacacc gtttattcgt aaaaagggat tgtgacaagt
    11641 cttttgtcac tacttaccga acgaaactga aggagctatc caaaaagtat cattagtatt
    11701 attctttgtg tttctagtgg caccactagt acatttaaaa aagctatcga tcatggacta
    11761 atcatacatg atcgatagct ttttagataa tgtttgttac gctatctgaa attgactatt
    11821 ataaagactg gcataaagcg ttggtgattg gagtagttca gaatgtgttc ctttttcgac
    11881 gatatcgcca ttcttcatta caaggatcat gtctgcattt tcaatcgttg acaaacggtg
    11941 tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc attgcttgct gaatcaatgc
    12001 ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa ataacgacag gaggattcgc
    12061 tagaatgact cgagcaattg tcaataattg ttgctgtcct tgagataacg tgccgttttc
    12121 gctagaaatg atcgtatcat atccgtctgg cagtgttcga ataaagtgat cacattgtgc
    12181 gatttcagcc gcttcgataa tttgttctct tgtggcatcc attttcccgt aggcgatatt
    12241 atcagctacc gttccttcaa acagccaggt attttgtaaa accatcccaa aagaacgacg
    12301 tagttctcca cgtgaaagct tggtaatatc aagaccgtcg aattcgatct ttcctttatt
    12361 cagttcataa aaacgcatca gcagattgac taaagtcgtt tttcctgcac cagttggacc
    12421 aacgatcgct accgtttgtt ttggctttac tgaaaaatcg acttgattca tcaatatttt
    12481 atctgatgtg taaccaaact gtacattttt gaaagctatt tttcctttcg gttgttctaa
    12541 aagtcttgca tctggaaggt ctggaatttc atctgtttca tctaatatct caaatatcct
    12601 atcgattgct gccattgcgg attggatcga gttgatcaca taagaagcgg tagaaattgg
    12661 ttcagaaatc tgattgatgt actgaagata agcttgtaag aagccgatcg tcacaccacc
    12721 tgatagaaca agcatagcac cgaataccgc acttatgatg aaggcgagtt gattaatgaa
    12781 acgaatggcc ggatagatag cacagttcat aaattgagca cgtttaaaag cgttgtattg
    12841 ctttttattt acttcgtgta tagcagcttc tgcatgagct tgctgattga atgttttgac
    12901 cactagatta ccagctaaga tttcttccat tcgattattt aaaacaccca gttcatactg
    12961 attctgttca gaaatctgtt tgtttttgtt cgcaatctta gttgtaacaa ttgaactgcc
    13021 aacgatcagc aataagacga gcaaagtaag cttgctttcg atataaaaca gcatcagacc
    13081 agcagcagct attgttacga cagaagtaaa aaattgattg atacctgtca ataacacttg
    13141 agaaagttga ttgagaccgg tagttgtccg actaatgatg tcacctactt gatgattgtc
    13201 aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt tcttttcgca ccctcaatgt
    13261 gatcttttcg cttaacgctg ccattgtccg ttcctgaata aatgaagtga tgctgcttaa
    13321 gactgaacag ccgatcagca ataagacagg gaacaacaat gcttgtttga tatcactgaa
    13381 agaaagctgt ccaatacctg tttttcttat ttctgataag agatcatcga tcccgattcc
    13441 catgatcaag ggcatggcta cgactaatag gttcccgaat aaactgcata gaaacaatcc
    13501 gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa cgtatcaaag cacgcgtgtt
    13561 caacgttttt ttcttttcca tcgtatccct tctttctata ttccttgtga ttttgcaaac
    13621 tcctgataag tttggcaatt agacagtagt tcttcatgag taccttgtcc aacgattttt
    13681 ccttcatcta aaacaatgat gttatctgct tgttggattg tactgaggcg ttgagcaaca
    13741 atcacgagag ttttctccga catgtgttta tgaagggctg ctcttaatgc tgcatctgtt
    13801 ttatagtcta aagcggagaa actatcatcg aatacataga tctctgctgg tttgatcaac
    13861 gctcgagcaa tacatatccg ctgtttctgg ccccctgaat aattagaacc gccttgagca
    13921 acaaagctgt ccaatccgtc aggaagggtg tccactagtt cttctaattg agcgatcttg
    13981 atcgctttag acaactcttc tgttgaggca tattcatttc ccatctgcaa gttgcttaaa
    14041 attgtcccgc tgaataagaa agccttctga gggacataac tgatgtggga gcggatctgt
    14101 tcttgagtca tttgagtaag aggaatacca ccaagggtta cttttcctat cgtagggtca
    14161 ctaagtctca agagaagttt cgccaaacta ctttttccag atccggtccc gccaacgatc
    14221 gctgttgttt ttcctttagg tattgtgaaa tcaatatctt ctagaactgg atcagagatt
    14281 tcagtatatt taaatgtgac atgttcaaaa gcagctgcat ttgtctgatc aaaggttggt
    14341 tcagctactg ttttgatcgt ctcttcctca atttcgatct ctgcttgcag tatttcttct
    14401 atccgtcgta atgaggcaaa cgatttaggg ataatgacca ataccatagc tgcgatcatc
    14461 aagtaagcaa gtgtcagcat agagtattcg actacagcag tcacgacacc gatttgtaat
    14521 gctccttctg ctacaagatt tccgccaaac cacaaaatag aagcataaac gattcccatg
    14581 agcaaaaaag caattggagt gacccaagca aatattcggt tcactttgat catttgatta
    14641 gcatagtcag caaagctctt attcgttcgc ttttcttcat atgattgatt atcaaaggca
    14701 cggatcatat taatcccagt aaagaattct ctcaatgtga tggtgatccg atccattttt
    14761 ggctggatac tcaaagataa aggtgcccct cgtttcatca gtcgataaac aatccataca
    14821 taaaaaacaa cagagatcaa tgtaacccat gttagtaata gagaataacg aaacatcatg
    14881 agaatggtga aaacgcaaat aaccggtgct ggtaagatca tttggcaaaa taaaacaatc
    14941 atttgctgga cattatcgac atcattcgtc attcttgtca aaagagatcc agaactaaaa
    15001 cgactgatat ccttcattga cagctgttgg aatttacgga aatatttctc ccgcgtttgg
    15061 aatccaaacc tagcggaagc caatgctgaa aagtaactag aggcaactgc agcgattgtt
    15121 cctagaaacg ctacaagcag catttcaact ccaatttttt ttataactga ggcttcgcca
    15181 cttgctatac ctgtgtcgat cagctttgct actaattttg gtacacctaa tgtaccggcg
    15241 atttctaaac agatcatcac aaaggtaagg agagcgagtc ctttgttttt ctgtaagaat
    15301 gtttttaaga tagacatatt attcctcctt ttttcctgat acttttcgat tctatacctt
    15361 caagtaactt gaaggtcaat agaaaaaaga ataaactgaa aaagaggtga gaaaaaatga
    15421 aaaaaatgta tacgattggc caagtatcgg aactatttga tttgccaaaa tcaacgatcc
    15481 gctattggga tgaacaagga ttaatccgtt caagtagaca agaagagaat gattatcgat
    15541 tgtttgatat cgatgatatt tttatgcttt atgatatcgt tttttataga aaattagata
    15601 taccgatcaa acagatgaag aatttatatg gaaaaacatt gacggagtta tatgagacac
    15661 ttgatgaaac agaaagaaga atccataaag aactggtggt gatgaaacaa aaacaaaaag
    15721 agataaggga gcaaaaaaaa cagttgaaat tgatgatcga tacaaacgag gaagaatttc
    15781 ctgtagaaga gatccctttt gactgtatga tctcaacgga gtttgaagat attgtggaaa
    15841 tcaaaaaatt tctacctaac tattcaagct ttgggatgat gagtatgcca gcttccagtt
    15901 cacagacgat gtatggattt tttatcgacc ctagtgaagt acatttattt actcaagacg
    15961 tgatttggga gaaaaaagat acggctgttt atcgtcgatt cttattgaaa tccgagatga
    16021 accatgcgga acgtaataat attttagaaa tcagagaaag aatgtatgaa aaaggatgga
    16081 aaacaggaga agtgatcggc cagtatctat tgacgaatac ggatgaaaac aatatcagaa
    16141 ctgaatatta tcatgcatgg atagaaatga aaaaatagga aatatgtgtt taagataact
    16201 cgaaaatgat ggttgtttta gttataaaga aaaattttct ggttcgatta cgggtttaat
    16261 gtgggggatt attagtcgtg gatagataga attttagttt tttagaggaa atatgtcttt
    16321 aaaaatggaa tggttgcaat tcttagcgat atatacgatg taattgtcct cttaaaaaag
    16381 tatggaaaaa taattgtatt gggtgttatg tataattcat ggtgaactga gactaatgag
    16441 aagaaaaatt catattgtta tgagtgagat tgtatcagat gagaatgata aattaaatag
    16501 gtgcataaaa gcattacact taaaatacat tgttgcttac
//
LOCUS       DADVXV010000065        16161 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.066, whole genome shotgun sequence.
ACCESSION   DADVXV010000065 DADVXV010000000
VERSION     DADVXV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.066"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(51..1598)
                     /locus_tag="KB969_002031"
     CDS             complement(51..1598)
                     /locus_tag="KB969_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBB6869998.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="KB969_002032"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="KB969_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBB6869999.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="KB969_002033"
     CDS             complement(2043..2237)
                     /locus_tag="KB969_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870000.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            complement(2463..3665)
                     /locus_tag="KB969_002034"
     CDS             complement(2463..3665)
                     /locus_tag="KB969_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6870001.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(3668..3862)
                     /locus_tag="KB969_002035"
     CDS             complement(3668..3862)
                     /locus_tag="KB969_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6870002.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(3909..4757)
                     /locus_tag="KB969_002036"
     CDS             complement(3909..4757)
                     /locus_tag="KB969_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HBB6870003.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(4962..5312)
                     /locus_tag="KB969_002037"
     CDS             complement(4962..5312)
                     /locus_tag="KB969_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870004.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            5907..6353
                     /locus_tag="KB969_002038"
     CDS             5907..6353
                     /locus_tag="KB969_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBB6870005.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            6977..7969
                     /locus_tag="KB969_002039"
     CDS             6977..7969
                     /locus_tag="KB969_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6870006.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            7985..8869
                     /locus_tag="KB969_002040"
     CDS             7985..8869
                     /locus_tag="KB969_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6870007.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            8918..10525
                     /locus_tag="KB969_002041"
     CDS             8918..10525
                     /locus_tag="KB969_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6870008.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            10526..12010
                     /locus_tag="KB969_002042"
     CDS             10526..12010
                     /locus_tag="KB969_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HBB6870009.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            12187..13179
                     /locus_tag="KB969_002043"
     CDS             12187..13179
                     /locus_tag="KB969_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6870010.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            13231..14100
                     /locus_tag="KB969_002044"
     CDS             13231..14100
                     /locus_tag="KB969_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6870011.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(14520..16085)
                     /gene="guaA"
                     /locus_tag="KB969_002045"
     CDS             complement(14520..16085)
                     /gene="guaA"
                     /locus_tag="KB969_002045"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBB6870012.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
BASE COUNT         4890 a         2825 c         3273 g         5173 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agtaaggtac tgttctatgg ggcgcttacg ttgaaaaacg ttgatttatc
     2341 ggcattcccc atccatatta tatttacgtc ttattcccac tcaatatgag tagcctcgta
     2401 aagaagctat tatatcagtg ctttttcagc ctattcctca ttttggtagg gaaatggtag
     2461 ggttagattt ttactgcttg atttccatta aagtttgcaa ctttagattt tgttgcacag
     2521 gtaaatttaa tgtttcctgt catttgttct gcaattcctt catcattacg gctccataga
     2581 tgagcgtagt gctttaaagt gatttcaggg ctagaatggc ctaaccgttg cgacacgacc
     2641 agaatgtctg cgttaaactc attgattagg tagctaacat gagaatgacg taatcctttt
     2701 ccttgtatta ggggtacctt agctagtttg gcataacgct gaataattcg ttgaacagtt
     2761 gaacgataga gtgggaggtc agtgtagcta agaataaatt gttctacacc atgatttttt
     2821 tgaataactt tccacttttt tagcacttca attgtatcat cgtccagaga aatgatccgc
     2881 aagccgcttt cagtttttgt gtaaggtttc cgaataaaat ctttttgatt tgtcatttcc
     2941 aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca cgtcattcca attaagtgct
     3001 aatccttcgc ttacacgaac accagtcatg taatatagcc agatcattaa aaaacacata
     3061 tgttcgtaga aatcatcttt ataaattttt gccaaaactt cttcaaattc ttcttttgtc
     3121 cagtaaggaa cgattgattt tccttttgga attgcttttg ttcttttgga aatattctca
     3181 ttcagaaatt gcagggtgac cgcatagtct aatgatttac gaaacatacc gtacataagt
     3241 gaactgtatg cttgtgagta tccgctatcg ttcaataacc aaattcgata attttcacaa
     3301 tctcgcacat tgatttcacg aagcttctta tcaccgaaaa attcagtaat ctgaatcaat
     3361 ccacactcac gagaactcca agtacttttt tgtacgctag ctttgtagtg tggaacgtaa
     3421 gactgctcca taaattcttt gtaagttaaa tcataattcg caaatccatt tacaaccatg
     3481 tattcatttt ttatacgcat gacttctttg tgtgcttcac gagctgatga gaatcgtttt
     3541 cctagagaat cttttgttcc tttcttctgg atcctctttc cagtcacttg atctgttcct
     3601 aactcaacta gataagaaaa gcgaccattt ttatcttgat acacacaagg gtattttgtt
     3661 ttcatagtta ttcctcctgt gaaagaggaa cacctataat ttcttcaatt acttgtcggg
     3721 gtactacccc aactctttta ttattataat atggatatcc ctgatttacc attcttgttt
     3781 ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa tcctagagcc tctaaatctt
     3841 ttcgacaaat tgtatttttc attgtataaa ctcactttca aagaaaacac tatcattggg
     3901 taatagtgtt atttctttat ttttgtataa tgaacggtac tttcttgaaa atccatcact
     3961 tgttcaggac ttcccaactc atttaaagct aaagcattgt aaaaaaatgg acgtctaact
     4021 atatattcgc ttgtatatag tatatcttga ttcgtggaat catagggttt ctttaccatc
     4081 tttttggtga cagttggtag tttgagattc cgggacttga aaaaagcttt tttcttatgc
     4141 tctttcaatt ccagctcttt atcgaaatat ttgctgatat agcgcccgcg attttcgata
     4201 ctgtctacat cgatcttgtt gatcttaacg aaaccctgac cccaaatcgt agttaaccgg
     4261 ttaaatgaga taaaggggaa atcaaacaag ataatatggt agtggattgc accgcgttgc
     4321 tgcttttccc acgtggcgag atactttaaa tttgcttttt tagttttata gaggtcataa
     4381 ttcagtcgtt tgataaattt tttaaattca ttatttgcat actcaatgtc ttgaatgttt
     4441 tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa aattcgtgtc tacaaggcgg
     4501 gcaatctcaa atcgcatact ttgataatgt ttctgtttgc gttttaaact gtcatattgt
     4561 ccttgagcgg ataattcatc atagtttttt cttttttcaa gagtaatatc attttcataa
     4621 atccaagcta atttttgttt tcgttccaga tttacttcgt tttcgatcgt tttacgtttg
     4681 ggagtaatga ttgcttcata atcataaatt tcaatatacg tgggagtttc aatgattttc
     4741 tgattataag cttgcaaaaa tcatcactcc ttgttgcgta ttcgattgtc aaagaaccag
     4801 tcattttctc ctgatgttga tctataaatc aagttaaggg ggaaggcctg cgtagcagcc
     4861 cttctagcct atggggtgtt gggcggtctt aacggacaga aacggctctg tgggcgctgc
     4921 cccgccgttt cgtcctaacc acccaacact ccatagtata gttagttttg tgtagtggta
     4981 ccttgttttc tgggaatcaa agttgccgta tcagcggttg ccgataaccc ataactgaca
     5041 aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat tggtaaatgt aattatggct
     5101 aaaccttgtt gggtaagttc ttccggcgtg atcacaggat gttcagattt gactttgaca
     5161 ctgatttttt cgtagcgaag ttttggtagg atacattcgt agctccaacc tagaatttcg
     5221 ccctcctttt gccagcgagt gacattgacg acttggtatt ctttttcgag tgtttctttt
     5281 ggtaaactga gatcggtaat ttttattggc atcacaattc tcctttttta tacgaaagtt
     5341 tatacgattt gattaaaaaa tatagatggc catctacgac ttgtattata tacgagaact
     5401 tatacgtagt caagagattt tctaaaaaaa tatatacgat tttttatacg agtgttataa
     5461 tgaaaaaaat gataaggagg aatttgaata tgtttggttt agtacaacct aataaagtga
     5521 aggtgggcca acgaatcaaa gaaataaaag acggaatgtc tctctctttt acagaattag
     5581 ggaatcgatt aggtttaaaa aagccgacga tcagttccta cgttcaaggc tatgcgttgg
     5641 ctcctaagag tgtgatcaac caattatcta gtatcagcgg aaaacctgtc ggctggtttt
     5701 attttgggca tgtggaagaa tatatccgag agtatttgtt tctcattggt cagaaaaaaa
     5761 tagtggacga ttatcctgaa atcattgaga aaataaagca agaattttat acgggcgagt
     5821 tcaaaaatcc tgcttgggag aatgagctag gctatccttt ggaggaattt atccaagaat
     5881 gttttgtaga atattcgagt gaaatcatga aggactatgt cgtacagatt acgaaagagg
     5941 tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa agcaaaagaa gaagctgtca
     6001 cgattctttc atctgggatc attgactata tcgagatgag tggtgagatc aagtatggag
     6061 agaaagatcg cattgcgaaa atggtgaaag aatcaataaa aacctttgat gtgaaacaag
     6121 acctgacatt taatgattcc tatttgattg gaaagttgat caatattctt ggtacagatg
     6181 aagatacgga gctgtttctt tcttctttat caatgatatt tactgataag catttttcca
     6241 ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc gatgcgacca gcgttaatca
     6301 aactctatcg ggagaaaaca ccagatgaat tttatgattg gtttgagaag taaaataaga
     6361 aaagtggctt agattacaag ttggtgaaaa aatttttttc agcataacat cagtaatcta
     6421 taaaggggtt gttgattata ctgtagaagt taagtactca agagattttt tgtacgtaaa
     6481 caaagcaaaa aagggtgcag tttcactaga aaatgtactc ttttttgtga tttttcttag
     6541 ttatagagtt tttttgaaac tttaaaaatg agaaaacata ttgattttaa agagtgtaga
     6601 catagcttct tttgctaaat agattaaact tactggtgag tggtcttgaa catactttta
     6661 aatcacattt tactgagttt tattggattt tataattcat tggaaacctc gtacttaatc
     6721 tgtttttatc tatcgactag aatctgtata tattccagct atcaatgagg ccgcagaaaa
     6781 gggtgcttaa aaataatctg ttgtttaaaa tattattatc agaatactta gatacaaaat
     6841 tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg atatggtaat ctataaacga
     6901 aaatagtggt aacgtttcca aaatgcatct tcgttaaatt tttatttttt taaacgaaaa
     6961 tggaaacgtt tctaaaatgt attgggagga gattgaattg gaaaagacat tgggaccagg
     7021 tggtgagata agggcggtac aacgggataa aaaaaatatt tcgaagtggg aaaaattaaa
     7081 gaaacagttg cggcgtgata agtggatgta cttgttgctc ttaccaggta tcatcatgac
     7141 gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt gcatttaaag actataatcc
     7201 tatgctagga attttggaaa gtccttgggt aggactagat cactttaggg aatttatcag
     7261 ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa attagtattt atggtttatt
     7321 gttaggtttt tttccaccaa ttattttagc actgagcttg aatcaaatta tcaataaaaa
     7381 aataaaacag aaaatccagt tgattctata tgcgccgaat tttatctcag tagttattat
     7441 tgtggggatg ctgtttttgt tcctatccgc aaatggacct attaatgggt tagtagaaaa
     7501 ggttacgggg caaccaatta tgttcatgtc taatccagct tatttcagaa cgatttatat
     7561 tttatcggga atttggcaag gaatcggctg gtcatccatt ctttacaccg caacgctggc
     7621 gggagtcagt accgatttat atgaggcagc aaatatcgat ggggcaaata ttttacaaaa
     7681 gatttggcat atcgatttgc ctgcattgag gcctgtgatg gtgatcagct tcatcttggc
     7741 cgccggcggt attatgaatg taggatatga aaaagcctac ttgatgcaaa cttcaatgaa
     7801 catccctgcc tcagaaatca tttccactta tgtatacaaa gtcggcttgc aatcaggtga
     7861 ttatgcctac tctgctgctg ttggtctgtt caatatgatt attaatgtcg ttttattact
     7921 gattgtcaac aatataacca agcggctaaa cgatggtcaa ggcttgtaat gaaaggagaa
     7981 aattatgaat agtgctttat caaaaatcga ccgtcaaatc ttatggttga atcgagtgat
     8041 tgtaactttt ttagtcgtca tcaccattgt tccgctgatt tatgtactgg tagcttcttt
     8101 tatggaccca gctactttga tcaataaagg tataagcttc aatccgaaag attggacaat
     8161 acagggatat caacgggtat ttgcagatga ttccatttta cgcggttttg taaattcgtt
     8221 gttttactct tttagcttca gcttattgac tgtatttatt acgatgatca ctgcgtatcc
     8281 tttgtctcga cctaacttgg cggggaaaaa gattattatg actttttttg tcattacaat
     8341 gttcgtgggt ggtggcttga tacctaccta tttattggta aagaacttgg gcatgttaga
     8401 tagtgtatgg gcgattatcg taccaggtgc tataaatgtg tggaatatta tcttagcccg
     8461 tacctatttt agtgctttgc caaaagaact ttctgaagct gctactatcg atggcgccaa
     8521 tgacttgcaa atactgttca aagtcatgct tccattagcg aaaccaatta tgttcgtatt
     8581 gtttttatat gcctttgttg ggcaatggaa ctcatacttt gatgccatga tttacatcaa
     8641 agatcccgac ttacagccgt tgcaactcgt attaagaaat attttgatcc aaaaccaacc
     8701 ttcacaagac atggtgggag ccaatactgc catggcagaa atgaaacaaa ttgctgagtt
     8761 gatcaaatac gcaacgatcg tcatttctag tctgccatta atcataatgt atcctttctt
     8821 ccaaaaatat tttgataaag gtgttttagt tggttctgtt aaagggtaag tattgttcac
     8881 tatttgtatg aataaaaatt ataaaggaga ttttaagatg aaagcaaaat ggatgctgcc
     8941 aatcgttttt acttccgtac taattttggg ggcttgtgga ggctcaaaag aaaagagtaa
     9001 atcaagccct gattatgaac tagaaaatgt ctcttttcca ttgaaagaaa aagtatcttt
     9061 aaaaatgatg tctcaaagtg cccctttggc tcccaatgat cctaatgaca aattgatttt
     9121 ccaacgatta gaagaagaga ccaatctcca tattgattgg acaaactaca gtagtgattt
     9181 tgccgaaaaa agaaatttgg atatcgctag tggtgattta ccagatgcca tcttcaacgc
     9241 cgctgcaggt gactatgatt tattaaactg ggcggaaagt ggcgttattg taccgattga
     9301 agatttgatc gaagattata tgccaaatct gaagaaaatt tttgatgaaa accccgaata
     9361 ccgacaaatg tctactgcac ctgatggtca catttactct atgccttgga ttgaagaatt
     9421 aggcgaagga aaagagtcga ttcatacagt aaatgggatg gcttggatca acaaggagtg
     9481 gttggataat ttgggtcttg aaatgccgca aaccactgat cagttgatga ctgtgttgga
     9541 ggctttcaag acgcaagatc caaatggtaa tggtgaagca gatgaaattc cttttagctt
     9601 tattaacaat ggaggaaacg aagacttaaa atttttaatg ggggcattcg gtctaggtga
     9661 taatgatgac cacttagtcg ttgataacga tggtcaggta caatttactg ctaacaaaga
     9721 agggtataaa gaagccatca aatatttcaa tgaaatgaat aataaaggtc ttattgataa
     9781 agaggctttc gaacaagatt ggaatacgta tgttgccaaa gggaaagaac ataagtatgg
     9841 cgtgtacttt acttgggata aagcaaatat cacgggtgca gatgatagtt atgacgtctt
     9901 gccagtctta gcgggaccag atggaacgaa acatgttact cgtacgaatg gcatgggttt
     9961 ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac ttggaactta cagctaggtg
    10021 gatagataaa atgtatgaac cgttacagtc tgtccaaaat aactggggaa cctacggtga
    10081 tgaagcacag gcgaatattt ttgaattaaa ggatggtatg ttaaaacatt tgcctttaga
    10141 ggggacagca ccgggggaac taagacaaaa aaccgaagct ggaggaccat tagcagttct
    10201 tgattcttat tacggcacag tcactactat gccagatgat gcgaagtggc gtttagattt
    10261 gatgcatgac acgtatttgc catatattac agaagacaat atctatccac gtgtcttttt
    10321 agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg gatatgtggg attacatcta
    10381 tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat gaagaatggg aagaatacct
    10441 tgctgaattg gaacgtgtag gtttggaaga atggattcaa ataaaacaaa ctggctatga
    10501 taattttttg aagggagcac aataagtgtt agtagaagaa acggcgattt tggataaagc
    10561 aaatcgattt attgaaatga tgcgaggaaa agttaaccct cagtatcgac aaaactatca
    10621 tttttccgca cccatcgggt ggataaatga ccccaatggg tttatatatt acaaagggca
    10681 ttaccatctc ttctatcaat actatcctta cgatagtcga tgggggccca tgcattgggg
    10741 gcatgcgcgc agtagtgatt tggtccattg ggaagatcta ccagtagcgt tagccccaga
    10801 tcaaccttat gacagcggcg ggtgtttctc aggaagtgca attgaaagag acggaaaact
    10861 atatttattt tatacaggct gtcaagaaat tgatggtatt agccatcagc atcaatgttt
    10921 ggcggtctct gaagatggta ttcattttag caaatacagt ggtaatcctg tggtagcaga
    10981 aaaacagcta ggtgaaaatg ggctaataca agaatttcgt gatcctaaag taattgttca
    11041 caacgatggt tactatatgg tagtagctac taaatctaca cagtctactg gtagaatagt
    11101 gatgtttcaa tcgtcagatt tgtatacttg gcacttttac tctgtgctgc tagaagggac
    11161 ttcagagcaa ggaataatgt gggaatgtcc tgatttattc catttagacg gacgagatgt
    11221 cttaatcatg tctccgatac aaatcaagaa gaacggactg gaatatcata atatcagttc
    11281 taccatggct tgtattggtg aggtaaactg ggaaacaggt cagatgatag ttgataattt
    11341 ccatgaaatg gattttggaa tggattttta tgcaccacaa acaacaagag atcctaatgg
    11401 tggacgggtg atgattgctt ggatgcagat gtgggatcgt acattgccta cacatgagtt
    11461 aggccatctt tgggcaggct ctatgagttt gccccgagag ttaagagtga aaaaaaatcg
    11521 attggtacaa aaacccatct caactgtata tagtcattta gtttatcaac aaggcagtga
    11581 aaatattgca gtgactgaca catcagtcgt atttcgaaac gcgctgtctg attcttcata
    11641 tttacatcta gtcgcagatt tggagaaagc tgaagttttt acaattgaat tactgcggtc
    11701 taagacggat tgtctcaaac tagcctatga cactgctaca caggtttttg aattggatcg
    11761 tcagaaacta ggaagagagc ttacaggggc ggaagaagac cctctgaatg tacgaaaagt
    11821 tgaagtacct ttgattgata atcagctcgt tcttgagatt tttagagata cctcatcaat
    11881 tgaagtcttt attaatgggt tagaagttat gacggctact ttctatgagc tggaaaaagc
    11941 tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt caagcttttg aaacagcgag
    12001 tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt atttaatagg ttttgaagga
    12061 taatgttttt agaaaagaac agatagctag atttcccatg gatttgctat tagtattttg
    12121 aaaaaattag taatttatga caaaattcat tatactaaac ttgtgcagaa atgtgaggga
    12181 tcaactatga aagcaacaat gaaagatgtc gcaaaattag caggtgttgg agtaggaact
    12241 gtttcccggg tattgaataa cggttctgtt aaagcttcta ctagagaaaa agttgaagca
    12301 gcaatgacag agttaaacta tcaaccagat ttttatgccc gggggttaaa gatgaagcat
    12361 acgaacacgg ttgctttgat tctacccacg gtatggcatc cattttttgg cgaatttgcc
    12421 taccatgtag aaacagcatt agaaagacaa aactacaagc tttatttgtg taactccagt
    12481 ggtaatagtg aaaaagaaca agaatatatc cagatggtca gccaaaataa agtagacggc
    12541 atcattggaa ttacttattc agatatcgat gaatacattt cgagtaatct gccttttgtt
    12601 agtattgacc gttatttcac tgaagaggtg atttatgtga ccgctgacaa tgcggccggt
    12661 ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc agaatgtagc atatatcggt
    12721 gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa aatattttga aatcgagtgc
    12781 cgtcaactgg ggatttccta taaagcgtta gatatgttag aacctttaga ccatctctca
    12841 gaacgtgtaa caaatttttt gttagagaat cccgatatcg atgggatttt tacgatcaac
    12901 gatccaatgg cattagctgt cattgatatg cttgaaaaaa tagggaaaaa cgtaccagag
    12961 gatgtccaag ttatcggatt tgatggtcaa aagatgacag aaggagatcc ttatctagtc
    13021 tcaacgattg cccaacctac aaagcaaatg gcggaagtgg cagtggcaaa attaattgct
    13081 gtcattaatg gagagacagt agaaaaacgt accgtattgc cgattgaatt tggcgaaggt
    13141 gacacaacga aacctttagt gagaaacgat tttgcttagt gcaaatacgt ttcttttttt
    13201 gaaaatgagt gaatgaaagg tgtagataaa atgttatatg gtggaataga agccggtgga
    13261 acaaagtttg tctgtgggat tggtaatgaa caattacaag tgatagaacg gaaaagtttt
    13321 cctaccacaa caccagaaga aacgatggag caagtgtttg atttctttga taagtacaaa
    13381 ggaaatatcg catcaattgg tgtaggagca tttgggccta ttgatattca aatcgaatca
    13441 agaacttacg gatatatcac caacacaccg aagttagctt ggcaaaatta tcattttgta
    13501 ggagctttgg aaaacgcctt gtcggttccc atctattgga ctaccgatgt aaatgctgct
    13561 tgttatggag aatatatggc agggtatgga aaaggtaaaa atagtgttct gtattacacc
    13621 gttggtacag gtgttggtgg tggtgctgta gtggatggga aaatagtcgc aggttttagt
    13681 catcctgaaa tgggacatat gctcttacaa cgtcataatg aagatcaatt tgaaggaatc
    13741 tgtccttttc atcatgattg tttggaaggg ttagcatcag gacctgcgat tgaaaaacgc
    13801 tttggaagaa aagcccagac tatctcattt gatcatcctt attggacgat tgaggcagat
    13861 tatcttgctc agtgtgtgta taacacaacg ttactatatg caccggaagt aataatttta
    13921 ggcgggggtg taatgaaaca gccgcaacta ctcgagttga ttcgccaatc gtttaaagaa
    13981 aaaatgggtt cctacgtgga tacgcctact ctcgaagaat atctactaac tccaaggctt
    14041 gctgacaatg cgggcttgat tggctgccta gctttagcaa taaagaaact caatcattag
    14101 aatagtattt attagaacta ttcataacat accggaagtt taaaagggta ttctgaaact
    14161 taaatagtct caattcattc ttctttcttg agaatctgag tagagacttt tattctgttt
    14221 caaattaata taattacgaa atgatattga gtacaagaaa gttcttttta ccagatcttt
    14281 taaatcgaaa aatctgatat atatatttat agtactaaaa atctgattag ataaaaagct
    14341 aattcaatag gaaaataaag gtagtgaata aaagcaaagc ccttgttagt agttaatcta
    14401 acaagggctt tggtagggaa aatggtagga aaccatctta ttttttacga aaatcaggaa
    14461 ctttagtaat tgaataatgt tgatttatag gtattcctca tccatattat gttggctctt
    14521 tattcccact ccactgttgc aggtggtttg ctggtaatat catacacgat acggttaacg
    14581 tgtgcgactt catttacgat acggacactg attttttgca agacttccca agggatacgg
    14641 gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac ggatacctac agtgtagtca
    14701 tacgtacggc catctcccat aaccccaaca gagcgaatgc ctggtaggac ggtgaagtat
    14761 tgccagatgt cgcgatctaa accggcattg gcgatttctt cgcgcaagat agcgtctgat
    14821 tcacggacga tttctaattt ttcttctgtc aattcaccaa ggacacgaat acctaagcct
    14881 ggtccaggga atggttggcg ccaaacgatg ctgtcaggca tgcctaattg ggtacctaat
    14941 tcacgtactt cgtctttgaa caatgtgttc aatggctcga tcagcttgaa ttgcatgtct
    15001 tcaggtaatc cacctacatt gtgatgtgat ttgatggttt gggcagtttc agttcctgat
    15061 tcgatcacat cggtataaag ggttccttgt gcaaggaaag aaacgccttc ttcaccggca
    15121 agtttggttg cttcatcatc gaagacatat acaaattcat ttccaatgat tttacgtttt
    15181 tcttctggat cagacacgcc agcaagtttt gataagaaac gttctttggc atcgactttt
    15241 ataatgttca agccaaattt tccgccaaga ctttccataa cttgttctgc ttcaccttta
    15301 cgcaacaata cgtgatcaac gaagatacat gttaattgat cgccgatcgc tttttgtaaa
    15361 agaacaccaa caacagagga atctactccg cctgaaaggc ctaataaaac ttttttgtca
    15421 ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga agttatccat tgtccagtca
    15481 ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca agtcatttcc atattcggaa
    15541 tggcgaactt ctgcatggaa ttggattccg tacattttgc gttctgcatt ttggatcgat
    15601 gcgatggggc aatctttgct ggtagcaacg acatcgaaat cagtcggtgc ttgggtaact
    15661 aggtcaccat gactcatcca aacggtttgt ttttcaggag tgttttggaa aagggccgct
    15721 tctgcagaag tgatttccaa ttctgctttt ccgtattcac ggtttttggc tggtttaact
    15781 tttccgccta atttataagt aatcaactgc ataccgtaac agattcctaa aactgggatc
    15841 cccaaatcaa aaatcttttc atcaatacca aaggccttct catcataaac actgtttggt
    15901 ccgccagaaa ggatgattcc tttagggttc attgccttta cttcttctgc ggtaatgcgg
    15961 tggctcatca actctgagaa aacaccgaac tcacgaatac ggcgagtgat cagttggtta
    16021 tactgactac cgtaatcaag tacgataatt tttggctctt cgtcaaatcg tgttggtgaa
    16081 gacaaatttg aataaaactt agtccgatat gcggcgcgtt ctgtgcgccg catatttttt
    16141 tagttttcaa agatcagacc t
//
LOCUS       DADVXV010000066        16109 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.067, whole genome shotgun sequence.
ACCESSION   DADVXV010000066 DADVXV010000000
VERSION     DADVXV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.067"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..1204
                     /locus_tag="KB969_002046"
     CDS             <1..1204
                     /locus_tag="KB969_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6870013.1"
                     /translation="EKEYKGVQAQFIKGKLDDSPSYCEHCRSVRIIRNGSYTTRTQIL
                     KVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDEHHQLTKELKQAILMELYENQSRKL
                     IAKKYFVSDGTVTRILREATKHYQSRMNFLPTVLCMDEFKSMKSVSGSMSFICVDGTT
                     HQLFTILEDRRLYKLTQYFLHFPRKARLKVKYLVMDMNASYCQLLKTVFPNAEIVTDR
                     FHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYRRLKRYWKLLLKDSTTWEPLKRHYH
                     RLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTEGFQETLKTISSTLPQ
                     SFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIAFGYRNFYNFRARIYL
                     QQGLIFEN"
     gene            complement(1587..2315)
                     /locus_tag="KB969_002047"
     CDS             complement(1587..2315)
                     /locus_tag="KB969_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HBB6870014.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(2293..3867)
                     /locus_tag="KB969_002048"
     CDS             complement(2293..3867)
                     /locus_tag="KB969_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBB6870015.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            4096..5034
                     /locus_tag="KB969_002049"
     CDS             4096..5034
                     /locus_tag="KB969_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6870016.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            5046..5957
                     /locus_tag="KB969_002050"
     CDS             5046..5957
                     /locus_tag="KB969_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6870017.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            5981..7453
                     /locus_tag="KB969_002051"
     CDS             5981..7453
                     /locus_tag="KB969_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBB6870018.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            7504..8115
                     /locus_tag="KB969_002052"
     CDS             7504..8115
                     /locus_tag="KB969_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBB6870019.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            8145..10058
                     /locus_tag="KB969_002053"
     CDS             8145..10058
                     /locus_tag="KB969_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HBB6870020.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            10186..13167
                     /locus_tag="KB969_002054"
     CDS             10186..13167
                     /locus_tag="KB969_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HBB6870021.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            13164..14825
                     /locus_tag="KB969_002055"
     CDS             13164..14825
                     /locus_tag="KB969_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HBB6870022.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            14865..15797
                     /locus_tag="KB969_002056"
     CDS             14865..15797
                     /locus_tag="KB969_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBB6870023.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         5222 a         2608 c         3227 g         5052 t
ORIGIN      
        1 tgaaaaagaa tataaaggcg ttcaagcgca gtttattaaa ggaaaattgg atgactctcc
       61 ttcctattgt gaacactgtc gatcggttcg tattatccgc aacggttcct atacgacacg
      121 cactcagata ttgaaagtca aagaaaagtt aactatttta gaattaaaac gtacccgttt
      181 tctctgccat gattgtggaa ggaccttttc tgcgaaaacg gacttagttg atgaacatca
      241 tcaactaaca aaggaactga agcaggcaat tctcatggaa ctgtacgaaa atcaatcacg
      301 taaactaatc gctaagaagt acttcgtctc ggatgggacg gtgacacgga tcttgcgtga
      361 agcaacgaag cattaccagt cacgtatgaa cttccttccg acggtgttgt gtatggatga
      421 gttcaaatca atgaagtctg tttctggttc catgagtttt atttgtgttg atgggacaac
      481 ccatcagcta tttacgatcc ttgaagatcg cagactttac aaactaactc aatacttcct
      541 gcactttcct agaaaagccc gtttaaaggt caagtaccta gtgatggaca tgaatgccag
      601 ctattgtcag ttgcttaaaa cagtctttcc aaatgcggag atcgtaactg accgctttca
      661 tattgtccaa cacatcaatc gcagcttcaa tcaattacgt gtccagatca tgaatcgttt
      721 tcgaacctca cactctgaaa atcagaagaa gtaccgtcgg ctcaagcgat attggaaact
      781 cttactcaaa gattccacga catgggagcc actcaaacgg cattatcatc gactgtttaa
      841 acgaccaatt agtcaaacag aaatcgttga tgagctgtta agctacaacg aagaattgcg
      901 aactgcgtat catttttgtc aattattacg ctattatttc gttaaacgag gtacggaagg
      961 ctttcaagaa acccttaaaa caatttcatc tacgttacct cagtcgttta aaaagaaatt
     1021 cacgatcttc cattgctacc aatcgggtat ttcaaatgcc tttaaggtgt cccactcaaa
     1081 cggcgtcact gaggggctga ataacaagat caagctgatt aaacgaattg cgtttggtta
     1141 tcgcaacttt tataactttc gggcacggat ctatttacaa caaggtctga tctttgaaaa
     1201 ctaaaaaaat atgcggcgca cagaacgcgc cgcatatcgg actaagtttt attcaaattt
     1261 gtcttcacca acacgatttg acgaagagcc tatttaaata actacatcca tttattctat
     1321 cttctaaaat agcctttttc atttcagtta aatagttcag cgccattttt gcactcgact
     1381 tgcatagtag ttttttccat attcctcaac ctcagcgggg gttgaagaca taaggaaaat
     1441 cctatgcgtt atgctcaact ggatctgatt aaatattcta atgtattttt ctctaccatc
     1501 attaaatggt taatagccaa aaatcaccac ttttcaatgg ctccttgttg tataagtata
     1561 actagaagat gaacacgtct gagaaattat agaagctttt tacggtaatt actggggctg
     1621 tgtccagtag tttttttgaa gagaacagaa aaatagctca cgtgatctat tcctactttt
     1681 tgactaattt catcaataga taagaatgtg tctttcagta gagcacttgc tcttttgatt
     1741 cgaaagtcta gcaagtaatc atgaaaggaa taacctgttt cttttttgaa ggcccgtcct
     1801 aaataagcgg gatggtaatg gaattgtgta gctacatctt tgagcgtaag cttttcacta
     1861 taattgtttt gaacgtaatc aatcacttgt tgaattgact cattaaaaga atcatcagtt
     1921 agagagtttt gattagctgc tgatttacgc attttttctt cttgtactaa cttaactaaa
     1981 taaggaaaat caatgggttt cgttatgtaa cttttaatag ataaatcaat cccctttttt
     2041 gcatactgaa aattttggtg ggcactaatg acaatactag taaagtagcg attggatgtt
     2101 tgttgcaaag attcgattaa ttcgagtcca gaaattttcc ccatcgtaat atctgtgata
     2161 agtaaatcaa agcgctggtt ttgcaggttt ttaaatgctt cgtctccgtc tgtgtagcag
     2221 tgatcgataa tgatgtcggg gactttcttc aaaagataat gccttatgcc ttctacaatt
     2281 gtacaatcat cgtcaacaat tgcaattctc aacatgcata ttcccccctt tttgtatttt
     2341 gatagtaatc gttgttccga cgtgtagttg gctttctata acaaaacgtg tatctccagg
     2401 atagagatgc tttatacgtc gaaaagaatt tgagatgccg atattctcac tataaggaat
     2461 atcatcatta agtttttgtt gaatatgctc cagcttgtct tggtccattc ctttcccatt
     2521 ttcaacgatt tttaacacat aatggttggt tgtttcagtt gcatagacag tcaaacgatt
     2581 ttcctttttt gatgaatcga agccgtgttt aatataattt tcaacaaatg gctgtaaaga
     2641 aagttttggt aacattaatt gatcaatatg atcaatcagc tgatagtcaa agttatgtcg
     2701 ataacgacgt tgatgtagtt gcaaggagag gtcgatatta attaattcct ctttcaaatc
     2761 aattatgtcg ggctgatatg tattattgcg atacaacttg ctcaataaat atatactgtc
     2821 gctgatttct tcgtcatcat tcaatatggc agtcattcga ataaattcca aattattaaa
     2881 tagaaaatga ggctcgattt gatattgaag tgctgcatac tttgcttctt gcttcaacca
     2941 attattttca taaagtgttt tttgatatgt agcattatct aaataaaact gattgatatg
     3001 catagcgatt tctttcaaat caccgacttt gttttcgata ttgattgact tgtagtctcc
     3061 tgtagatgaa tgatttaagg aagtaatgat ttcctgatac tgctggatat agttacgaaa
     3121 acttctattt aataattgat gaatagcaag aataaacaaa ctcattaata agaaaatcat
     3181 gattgccaga cctaataagg tttgtgacga ataatttgga ttttcatata cttgtaatgt
     3241 gtggttaccg atagctatct gttgcgtttt tttccattta gaaggcgaga tgtcttcaga
     3301 taaattgacg gaatcaatac cattagacaa agaataattg taatgtgttg gaaagagact
     3361 cttttttagc gcgttgatcg aaacgtctag aatcaatgta gcatcgggca tgtcctcact
     3421 aatgaaactt aatgaacgaa taaaagaaat tttttcgttt tttgtaggtg cgtaggcact
     3481 taagtatttt tcgtaatcta atgagataga tatattttta acttcatcat cttgcacaag
     3541 tttttttaag ttatctacta aataggtagg ggagcgatcc tttgacaaaa tatcttccat
     3601 gtattcagca ggtgatgaga ggtagtagtc attaaggttt tcttggaaat cataattttg
     3661 atagatctct gtcacgatac cggagagaat acgattatat gtttccatat agtgggtgat
     3721 ttgctgaatg ttttgcaggt tttgattttt ttctttttca atcacattga tataggaaaa
     3781 gaacaatgtg aaacaggcaa gtaaagtaat aaaaaaaatc aatatgtatg taaaacgcat
     3841 aataactttt gataaatcgt ttttcattca aagtcctcat tttgataatc tctaatttta
     3901 tgaatcatta tagcacatat tacaagtgat gtaaacgctt tgcaaacagg gctacttatg
     3961 attgtgaata cagtttccgt ttaaaaacta ttctattgta gaggtttaat aaactaaaaa
     4021 taatgtataa aaaattaatg taagcgatta accaagtggg tataatcaag gaaacgctga
     4081 gagaggagag acaaaatgaa gctaaagaaa gggttattag gaaatctaaa aaaaaaccga
     4141 gcattgttta ttatgctttt accaggtgcg ttatggttat ttatattttg ctatatacca
     4201 atgtttggag ttgtaatcgc ttttaaagat ttcagaattt catcaagggg attctttaca
     4261 agtttgttca acagtccttg ggttggctgg gaaaatttca aatatctctt tgcttcgcaa
     4321 gatgcttgga tcattactcg caatacggtt gtttataacg ttgtaggtat tttgctaagt
     4381 actttttgta cagtgtcatt agcaatcatt ctgagccaaa tggcgaacaa acggttattg
     4441 aaaaagatgc agacatttat gatttttcct aattttttat catgggtagt catcagttac
     4501 tttgtttacg catttttgag tacggataaa ggattaatta atattttact aagcaatttt
     4561 ggtgtggaac ccataaattg gtatagtgaa ccgaagtact ggccttttat tattgttttt
     4621 acgagtttat ggaaaggcgt aggctatgga tccatcattt attacgcgtc aattatgggg
     4681 atcgatacta gttattatga agctgcttta gttgatggtg ccagtaaatg gcaacagata
     4741 aggaatgtag tcttgccaca tttaagatcg attattgtca ttatgttgat tttgtctgtt
     4801 ggtagtattt ttcgagctga ttttggattg ttttatcaat tgccaagaaa ttcgggggct
     4861 ctttatgatg tgacgaatgt attagatact tatgtctacc gtggattaat gaatagcgga
     4921 gatatcggaa tgtctacggc agcgggatta tatcagtcat cagttggctt tgtcttgatt
     4981 ttgattacta ataagatagt caacaagtta gatcctagtt cagcactatt ttaggaggaa
     5041 tcaaaatgat atcaaaatta aaacggcaga tgtacttttc gctgccagtc gaacggtttt
     5101 tcacaatatt actaatctta tttactctta gctgtatttt tccctttatt ttcgtaatcg
     5161 tcatttcatt aacagatgaa aaagcattac aactcaacgg ttacgaatta ttgccggctc
     5221 aatggagcac tgatgcatat caatacttaa tacaagatgg cggacagtta cttcggtcat
     5281 taggcgttac aattatgatt acagtgattg gaacgttgat tactgttttt atgacgggaa
     5341 cctatgctta tgttttatca agagcctctt tcccttaccg gaagttcttt actttttatc
     5401 ttttttttac catgttattt gcgggaggga tggttccttc ttacttagtg atgacgaaga
     5461 tgcttggctt aaaaaataca atttgggctt tgattctacc tcttgctttt agcccataca
     5521 atgtcattat tttaaggaca ttctttaaga agtcgattcc agaatcgatt atcgaatccg
     5581 ctaaaatgga tggctgtagt gagtttcgag tttttttcca aatcgttttg cctttagcga
     5641 tcccaggggt tgcaacaata ggtttatttt caagcttagg ttattggaat gactggttca
     5701 acgcattgct gtatattgac accaacaaat tgattccatt gcaatatttg ttaatgaaga
     5761 ttcaaaattc aatggaattc ttagcaaata ataatgacat tacattagcg cagcaacaag
     5821 caattcaaaa tagccttcct caagaatcaa cacgaatggc aatggtcgta gtagctactt
     5881 taccgattgc aattgtttat ccgttcttcc aaaaatactt tgttcaagga ttgacgatcg
     5941 gtggagtgaa agaataaaaa agaataggag atgttaaaag atgaaaaaga acatgcagaa
     6001 atatttgatt ggtggtgctt ctgtactaac ccttggccta ttaggtgctt gtggtagcag
     6061 taatggcgaa gcaaataatg aaacaggaac cacaaaagtt acttggtatc aggttggaga
     6121 agaacccaaa gattttgatg aggtcatgac aaaagtcaac gaaaaattaa aggaagaaat
     6181 caatgtagag ttggatatgc ggctgattcc ggacggggat tatcagcaaa agcttggtgt
     6241 gatgatcaat tcaggagaag aatatgatat ttgtttcgtc aatggcacag attatgtgaa
     6301 ttatgggaac aaaggtgctt tcattagtct caacgatcat ttggataaag agttgaaaga
     6361 ttatgcagct gaattgaatg aaggatttat tgaaggtggg gcaattaatg gcgaaactta
     6421 tggattgcca gtcaataacg atattgccac aacggaatat tggaccttta ataaagattt
     6481 ggtagatcaa taccaattgg atgtagagaa tgttgaaggt gtagaaacat tggctccagt
     6541 attagaaaag tttgcagaaa aaaatactga tacgaatatt acgccaatcg gtatgacccg
     6601 taccagtgtc tgtattcctt atgacaatat tatcggtggt ggtgtaccgc tagcggttgc
     6661 atttgaaggc gatacacaaa cagttgttaa tacttatgag actccagaaa tgatgactta
     6721 tttgaaggct atgcatgagt tttataaaaa aggatatatt ttgaaagatg cagccactgt
     6781 tacgacagat ccatttcgaa ttgatagtaa aaactggttt ttaggtcgta actcaagtgg
     6841 ttatcaacca ttagcacaaa aaaaattaga agctctagcg ggacatggat taattttaaa
     6901 accagctgga aaagctttta aaacgactgg atttgcaaga gtggcaatgc atgcggtatc
     6961 tgcttcaagt aaacatccgg aagcagcctt gaaattgttg aattatgtga ataccaatca
     7021 agaagtagcg gatttaatgg tttatggaat tgaaggaaaa cactatgatc gcaatgaaga
     7081 tggttcgatt actttaacaa actctgatga ttattatcaa ggcgcttggg cattggtaaa
     7141 tacttatcta gtttcaaaaa cttcaccgat tacagaagaa agtaaaaaac tagaagaaga
     7201 aagtaaaaag tttcaaaatg aagcaccgat gtctcctatt ttaggtttct cttttgacgc
     7261 ttctgatttt cgaacagaaa ttgcaagtgt acaaaatatc gtgtcacaat atgaagtact
     7321 tttaagctcg ggaacagttg accctgaaca atatgtacca gagttgttag aaaaactaga
     7381 aaaagctgga ttggataaaa ttcaggcatc tgctcaagaa caatacgatg aatggcgaaa
     7441 atctaacaaa taatttttta ctaaatgaaa agaatagact aagcagttag tggggggatt
     7501 caaatgaacg aaaacaaatg gaccaaagga tttaattggg tttttcaatt gttgttacta
     7561 aactttactt attttatact aatttgttta ggatttggaa ttttaggttt tttccctgct
     7621 acgatagctt tgattgctgg cgttgtgaat cgaaaaaaat atggcttgca agagtctgtg
     7681 aagttcatga gtaaaatcta taagaaaaat tttgttagat ataatctata ttgctggtca
     7741 gcaactttgt tgttggccgg caatattact acgatctggc tttgttggca gcaaagcgca
     7801 ccattgtttt atttattaag tacattatta tcggtaatta cactgttcct agtctttgca
     7861 atgttgaatt gggtcgtgat caaaagtctt gggttgtgga tgatgggaga ccgactgatt
     7921 gactatttgc ttttcacagc aacgatgttg ccaacggtag tcatgcaagg cttggtgctt
     7981 ggaatttatt tccgaatatt gatgattttg cctgtgattt ttctgtttgg cggaacagct
     8041 gtaacggtaa tattgattag taaattaact gaaagagcgt tagcaaagtt gccttgtcag
     8101 atacaatcgc actaattttt tcacaaaaag gagtatttct ttctatgaag ttaactgata
     8161 aacaagtagc taatatagcc tttatccagc aacttgagat tccattgaca caaaaagatg
     8221 aagaacaaat agacttgatt tttactgaca caaaggctaa tgtgcgacaa atcaagatta
     8281 ctaaaaatga gcagcaacga atttgcttgt cttattcaca tgaagacttg ctgtatcgag
     8341 gattgtttat ctgccttcca cgttttttag ctcaaggagg agagatgcca tacattgaag
     8401 aaacctcgat cattgagacc agttattcat tagatgcttc tcgtaatggc gtgatgaata
     8461 aagagactct aaaaaaattc atttcttact tagcgttgat ggggtacaac acattgtata
     8521 tttacacaga agatacctat gaagtagaag accttccata ttttggttac cttcgcggag
     8581 cgtatacaaa agaagaagtg aatgaaattg ttgaatttgc ttctggtttt ggcatagaag
     8641 tagttccatc gatccagacc cttgctcact tgacccaatt tttgaagtgg tatgctcaac
     8701 aagaactgat ggatgatcaa aatactctac tgatcggtga agaaaaggtt tatgcggcaa
     8761 tcgaaaagat gattattgcc tgcaaagaaa tgtatcagac agagcgtatt catttgggaa
     8821 tggatgaagc ctatcaagca ggtctgggac gatatttaag cctgtatggg tattgtgatc
     8881 ggacaacttt aatgattcaa catatggacc gtgtgttatc aattgttgat aaatataaga
     8941 tgaaaccaat gatttggagt gatttcattt ataagctatt agatgaaacc ggtaaagata
     9001 ggtattacaa tcctgatttt aaactcaaag cattagcagc taaaggatta ccagcaggat
     9061 taacctatgt tcattgggac tatggttcag atgaagtttc ctcctatgag aaagtaattg
     9121 ataaccattt gaaattttgt gacattgatc attacgtttt agctagtggt gcccatatct
     9181 gggggagact agccccgaat catgggaaaa cagaagcaat tgtttctgca gctgtaaaag
     9241 cttctaaaaa taaaggtgta cgttctgtga tgttaactac ttggggagat gaagggcagg
     9301 aaacagagca ttggcattcc ttaattgggg cattaaaatt agcagattat gtctattctg
     9361 aagaagagtg gaatgatttt gaggaaatct acgatcgttt attaggaaca ggtagttatc
     9421 aattaatgtc cgaattacga tatttcgatg aagtggatac cattacaaat aacaacttac
     9481 aaatggcttc cgtgagtaaa ctgctacttt ggcaagatcc gttagttggt atatatgact
     9541 ttcatgtagc cgctcataac aaaattgcca ctagaacaat tggtacttat tatcatgagt
     9601 tagctcagaa attagatatg aataaaaatt ggaatccaaa acaaccaatt ttaacaacta
     9661 ttcgtcaacg atatatactt ttagctgaaa ttttagcaca aaaggcagaa ctaggcatct
     9721 atttacaaca ctgctgtctg gtagaagacc ttgcaggatt aatggaatta gcgaatcggt
     9781 gtgaagcact agccaatcga gtaaatgaat tggcatctat tcatgaaata atttggtatc
     9841 aaacatacaa aacctatggt tgggaagtat tagaacaacg atatgctgca ttagctcatc
     9901 gtctgaaaac cgttgcgcgt cgtattaaaa atcatcttca ggggcaagat gccctagagg
     9961 agcttttgga agaacgatta ccgttttgtc aatatcaagt gccgcttgaa atttctggct
    10021 ttaattatcg gcaaagctcg gtgtcaggct acaattaacg aaggaatctt cccgttgaac
    10081 ggaccacttg ctcatctaat gggaaagtgg ttcgttttct attcataagt agcttaccac
    10141 taactctttt attaagaaga gaaaaaaagt aggaagtgag aaaatatgtt atcggactat
    10201 tatcaaaatc tgtcagttat aagtgtcaat acagaaccat tacgtaatta ttatattcct
    10261 tatgcaagta aagaagaagc aaaacaagag ttagaaaggg aaaaaacgag ccagtttatc
    10321 gatctcaatg gtacatggga ttttcagtat tatccttctg tccaacagtt accggaaaat
    10381 ttttttcaag aggcctttac tgaaagctat gatagaattt ctgttcctgg agtttggcaa
    10441 acagagggat ttgacttacc tcagtatatc aatgtatctt atccaattcc ttttgatccg
    10501 ccttatgtac ctaatgatac cccttgtggt gtatatcggc gtcagtttca aattgagcaa
    10561 acagatgcac gcttttactt aaatctagaa ggagcagata gtaattgttt tgtttggata
    10621 aatagaaact ttgtaggcta tgaccaagtg agtcatagta catctgaatt tgatgtgacc
    10681 aagtatttac aggttggggt taatgaaatt caaattctag tgatgaagtg gtgtgatggt
    10741 acctactttg aagatcagga taagtggcga atgagcggtc tatttcgtcc agtgtatctt
    10801 cttcaacgac caactatgca tctgacaagt tatcaactac ggacgttgac tgatcctaaa
    10861 aaaggaagcg gaacattaat ggtttctttt caacgattta ctcctattga agtatcgtta
    10921 cctatttctt acgaattatt ccatcctgat ggacgtctca tagcgaaagg ggagtgttac
    10981 tcggaacaac aaataaattt ggatgttgaa gattgccttt tttggacagc agaaacgcct
    11041 aaattatata cattactttt aacatgtaat ggtgaatatt ttaaagaaaa agttggcttt
    11101 cgagcactga cgatcaagaa tcgtaagtta ttgctgaacg gaacacctat taaattatat
    11161 ggagtcaact atcatgacgt gaatcagcaa ggcacgccag tgatgacccg agagcagtta
    11221 cgtgcagatt tgttattaat gaaaaaatta aatgtgaata ctgtacgaac ggcacattac
    11281 cctaaatcac cagattttta tgaattggcg gatgagattg gtctgtatgt aatcaatgaa
    11341 gcagatttgg agtgtcatgg tgtggttaat ctatatgata ctgaagcgaa ttatcaacta
    11401 attgctaatg atccgacatt cgaaaagccg attatggacc gagtgatccg ttctattctt
    11461 ccttatcaaa atcgaagctc tatcattatg tggtctatgg ggaatgaatc tggttatgga
    11521 gtaaattttg aaaaagctca agctttagca cggaaattgg atgattcacg gttgattcat
    11581 aatgaacgct cgattgaacc agttattgac caagtgaatg attttagtaa cttggatgtt
    11641 attagtcaaa tgtatccccc actggaagat gttcatcgtc attgtcaaag aagtgatact
    11701 gaaaaacctt tttttatgtg tgaatatagc cacgctatgg gcaacggtcc tggagatctt
    11761 aaaacgtact tcgatttgat tcaacagtat gattcctttc ttggcggttg tgtctgggag
    11821 tggactgatc atgcaatcaa tagaggaact ttagaaacgc catcttattt atacggtggt
    11881 gattttggtg aaaaatatca cgacggcaat ttttgcgtag atggtttatt gaccccagat
    11941 cggcaattaa cagtaggtgc attggagtac cgtaatattc attcgcctat tcaactgatt
    12001 gctgtagatg aggagctgca agaagtaacc ttgagcaata taactgcttt tacagccggt
    12061 tcagcattta acctttctct tgaatggtat atagatggaa aaaaaacagt ttatgaagta
    12121 atgaatcctt tcatacttga gcctggcaaa agttgttcat tgcccatcac agtacctaca
    12181 acgattcatg gtgctcatac ggttgctgtt tcgctatctg tttataaaaa tgatgagctt
    12241 tatggacagc aacagctctt tcttaaaaaa gaaaaaatga gattgccaag aactgctcat
    12301 cataatgatg caccacaaat ttcagtaaaa ggcacagagc tgataatcaa aggagaatcc
    12361 tttatttata tatatcaatt agcaaaagct gcgttcactt ctgtaaagat caatcaaaag
    12421 gaacttttgg aacgtcctac tcaattttca atttggcgtg caccaacgga taatgatcgt
    12481 aacttagtaa acaaatggaa agcagctgga tatgctgaaa tgtctttaga aatcagaaaa
    12541 aaagactgga aattcgtaga tgatcatctc ctgatcgaaa cgtcttatcg aggagttatt
    12601 ccaggattac agccaatttt tacaatgcac atacagttga aaataaatgg tgcaggcgta
    12661 atcaaccaaa aagtatcagt ggagaaaaat ccgatttttc cagatttccc tcgctttggg
    12721 atggactggc cgttgaatga tactttttcg aaggtttctt attgtggcta tgggccgtat
    12781 gaaagttatc ctgataagca ctatgctgcg atgtttggta tttatgagat ggagattgag
    12841 gaatttgatc agccatatat caaaccacaa gaatatggta accgctggca atgtgattgg
    12901 gtatcaatca aaaatcatca aggatctacc atgacggttt atggaaactc taatttttct
    12961 gctctgcctt atagtcaagc tcaattaacc gaaaagtcac accattatga attaataaaa
    13021 gaaaatagaa cttggttcaa tttaagttat aaacaaaatg gtatcggctc acacagttgc
    13081 ggtccttatt tagaagatcg tttccgtttt atggaagata cttttgactg gaatatagtg
    13141 attactttca aaggagaaaa tagatgaaag aaacaaagat caatcaagtc aaaaaaaaat
    13201 tatctcgtta tcaagaagtt gtttatcgaa accattgctt aaaatggtca aaaaataagc
    13261 tgaatgttcg ttttaatgga ttattttatc gtttcgaaca gttagaagaa gtctggaaac
    13321 cggtaacgaa tttccaatca tgtcctgtac agctcataaa tgatccaaaa gaaacatacg
    13381 atttatgtat aacacacctt tataaccagc atttgaaaaa tgacggattt tatttaaagg
    13441 ttactaatga caatcaactt acgattgaat cagcaaacct tcgagggttt caatatgcta
    13501 tggaagcctt attagagagt tttttttcgg taggagatca attattatta ccggaattga
    13561 ttctgaaaca tgaaccatca gtgaaaattc gaggaatcat tgaagggttt tatggtatcc
    13621 cctggacaca tgaaatgcgc ctctctcttt tttcatatat gaaagataac caattgaata
    13681 cttttatgta tgcccctaaa gatgatgaat tattacgtaa aaaatggcgt gaactctacg
    13741 atgcgcaaga attagacaaa tttaaggagc ttttatctgc tgctgaggct agcaatatcg
    13801 atttttggta cttaattagt cctggaaatg atattgatat tacgtgtgaa gaagacattc
    13861 aagttcttct gaaaaagtta gaacaactga ttgagcttgg cgtatttcaa tttggtctat
    13921 taatggatga tattgactat caattaaaag gtgctgctaa acgccgtttt cgagagccag
    13981 cattcgctca tgcctattta gtgaatcgag tagaggaata tcttagcact cggttgtcca
    14041 atcatgaatt agtcatttgt cctacagaat atgataatcg tcatggttct cgctatttag
    14101 caacgttaag tcaagaaata ccagaacaat taccgttctt ttggactggc ccaagcacgt
    14161 tagcggcgtc aatttctaca gaagagctgc aggaaatggc ttctgtctat caacggccga
    14221 tgctgatttg ggataatatt ccggtaaatg attatttaga ggataaagaa ctattgttca
    14281 tgagtccata tgagaatcga acaccgaatc tttctaagga gagataccag gttacaggag
    14341 tagtttcgaa tccaatggct caattagaag cttcaaagtt tacgatcaat agtatggcta
    14401 attacttatg gaactgtgag cgttttgatc ctttggaaac ttggacgtca gtcgttgaaa
    14461 aagtagttgg aagtaaacta caaccagctt atcttacctt aaccaatgct tttccaaatc
    14521 attacacaag cagtctgctt tcagatgaag aattactgct agccaaagac ccagaatggg
    14581 tcacaaaaga aatggctgct ttagtccaag cagtaaaatg gatccagcaa gaacaacata
    14641 catctagatt gagaacagaa ttggagcctt ggttacaagc aatcacagaa agttggactt
    14701 tctggcaaga atggcaatta aaaaaagatc caaaagaagc agaagaatgg ttggctaaga
    14761 aaaaaacaca ccgcatagga cgtgatttag taactgccca tttagagcaa attatcaaaa
    14821 gttagatatc ttaaaaaata aaaagcaaga aaaaggagaa caaaatggtc aagagattaa
    14881 ttagtgcaaa ctacagtgat gtcaagaaaa tgacgtcaaa agagttgaag caatccatca
    14941 aagcgagtga aggacgggtg attgtttgtg aaacggttgc taatactctt ccacaatctg
    15001 gagaaattac gaatgcagaa gttgcgtcag catttggtgc agatttgatt cttttaaatg
    15061 gtttcgattg ttatcgtcct gcagtttttg gactaccaaa tgtgacgatt gagaaggttt
    15121 ttgatctaca gcaaacgatt gaaaacccga ttcctaaatt aaaagaacta gtcggtcgtc
    15181 ctgtgggaat taatttagaa cccattgccc ctaaaacaaa tatgatgagt gagaaagtag
    15241 aaatcagcca aggaagagca agctctgttg aaacgataca aaaagcagaa gaactaggag
    15301 tcgattttat ttgctttacc ggtaatccag gcactggagt aaccaattta gaaattacta
    15361 aatccgtaaa aatggcaaaa aagtattttt cgggattgat tattgctggg aaaatgcata
    15421 gcgccggctc agaagagcca gttgtgaata aagaggcgat tatttcttat gcggaagcag
    15481 gcgcagatat tttactagtt ccttcagtag ggtctatccc aggcttttta gagcaagacc
    15541 taattgaagc ggttcggttg gcaaaaaaat atgatttgtt aacgatgtct gcaatcggta
    15601 ctagtcagga aagtgcccga ccagaaacat tgcggcaatt agccattatg aataaaagtt
    15661 gtggtgttga tttacaacat attggagatg ctggatacgg gggattggca ccagcagaaa
    15721 atattttcga aacctcggtt gcaattagag gaatgcgaca taccatcaac tgcgttagcc
    15781 gctcgatcaa tcgctaacaa aattaaataa aaaatggtta aattgattat ttaagtggga
    15841 acatacttga gatatcagct aacttctgtc actttaaaaa agggactgtg acagaagtga
    15901 aaatagacaa aaaatatccg aacaagagac taggatagca gaaaaactat cgttttgcaa
    15961 cgaggaccaa ctggaccgta ggagcaattc tcttattgtt cggatatttc gcttgttcaa
    16021 ggacttatgt ctgtagtgcc cttttttggt aggaaaaatg gtagggaacc atatcatttt
    16081 taatgaaaat caagcatttc aaaagttga
//
LOCUS       DADVXV010000067        16042 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.068, whole genome shotgun sequence.
ACCESSION   DADVXV010000067 DADVXV010000000
VERSION     DADVXV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16042
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.068"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            226..894
                     /locus_tag="KB969_002057"
     CDS             226..894
                     /locus_tag="KB969_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBB6870024.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1324)
                     /locus_tag="KB969_002058"
     CDS             complement(1094..1324)
                     /locus_tag="KB969_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870025.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1451..2833)
                     /locus_tag="KB969_002059"
     CDS             complement(1451..2833)
                     /locus_tag="KB969_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6870026.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2989..4176)
                     /locus_tag="KB969_002060"
     CDS             complement(2989..4176)
                     /locus_tag="KB969_002060"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBB6870027.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4183..5214)
                     /locus_tag="KB969_002061"
     CDS             complement(4183..5214)
                     /locus_tag="KB969_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBB6870028.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5260..6684)
                     /locus_tag="KB969_002062"
     CDS             complement(5260..6684)
                     /locus_tag="KB969_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6870029.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            6859..7764
                     /locus_tag="KB969_002063"
     CDS             6859..7764
                     /locus_tag="KB969_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBB6870030.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7855..8532
                     /locus_tag="KB969_002064"
     CDS             7855..8532
                     /locus_tag="KB969_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBB6870031.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8529..8699
                     /locus_tag="KB969_002065"
     CDS             8529..8699
                     /locus_tag="KB969_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870032.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8813..9709
                     /locus_tag="KB969_002066"
     CDS             8813..9709
                     /locus_tag="KB969_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBB6870033.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9764..11134)
                     /locus_tag="KB969_002067"
     CDS             complement(9764..11134)
                     /locus_tag="KB969_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6870034.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11372..12118
                     /locus_tag="KB969_002068"
     CDS             11372..12118
                     /locus_tag="KB969_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBB6870035.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12115..12954
                     /locus_tag="KB969_002069"
     CDS             12115..12954
                     /locus_tag="KB969_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBB6870036.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12955..13905
                     /locus_tag="KB969_002070"
     CDS             12955..13905
                     /locus_tag="KB969_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBB6870037.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14046..14798
                     /locus_tag="KB969_002071"
     CDS             14046..14798
                     /locus_tag="KB969_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870038.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14817..15968
                     /gene="queG"
                     /locus_tag="KB969_002072"
     CDS             14817..15968
                     /gene="queG"
                     /locus_tag="KB969_002072"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBB6870039.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5203 a         3000 c         3229 g         4610 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt tgataccgtt
     1381 gactagttct tccatcgcaa aagcagtccc ccattttaat ccaaatggcc gatctcgata
     1441 ctcgttatag tcaatgaatt tttttgctgt ccgtctcatc ttttccacct tctaatccac
     1501 tcataccacc tgcatgcccg ccaacgagag aactacgtgc gatggcgcgt cctccttgca
     1561 agagactatg cgcatggatg attgattgaa agccgtattt ttttctaatc gtatcgacaa
     1621 caaaatcaac tttcgcttca tttatctgct tttcaggatc ttcaaaaagg ttaagctgta
     1681 aacctgtcgc gtatacgagg tcggaacagt tcacgcctac acgccgaata tcctggtagt
     1741 ggtaatgctg gtggaaaatg gtcaataaag catctgcaag atctctgcta gcatttgtcg
     1801 cttcgatttt catttgctgg tgaaacccgg tcttgccatt tggatcaaga tagcctaaag
     1861 agtatcctac ccataagctg actacttgtg tttttgctgc agatcgtctc aagcgagtgc
     1921 cgacttggtc ggccatttct ttgataacga tctcgatttc ttctcgtctt gtataatctc
     1981 tatctaggat ttgactattt ccgatacttt ttgattttgg tgtatattct tgtcccaaaa
     2041 aacttcgatc gatgccccaa gcatgggcat aaagctgagt accgatgacc cctagcttgc
     2101 ttttcaagtg ataataatcc gcgtgagcta aatcataaac agaatgtata cccatttgtt
     2161 tcagacgttt tgctgttcgt ttgccgattc cccaaaagtc agtgatatct gagattttcc
     2221 ataacttttc tggtacatct tcataacgcc attcagcaaa catttgcttt ccgtcttttg
     2281 agccattgtc taaggctagt ttagcaagta gcgggttatc gccaattcct atagtcgtgt
     2341 agattccggt ctgctcaaac acatctttat ggatcagttt agccatgtcg tacgcatttg
     2401 ttttaccaaa gagtgccatg ctatttgtta catcaaggaa gctttcatcg acggaataga
     2461 catgatggtt cgcttcgtct gcatattttt tatagataga attgatttct ctgttctttt
     2521 ccatataata ggccatcctt ggggcaacaa tatataaatc acttggatag gggaagggaa
     2581 gatctctggc acggctgata ttggtgatgc cgtaagcttt ttttgctgca ggactggaag
     2641 ccaagattaa tccgctaccc cgtgtttctg tcgaatcgga cggataggac atgactacta
     2701 atttagttgt aaggggatca agatcctttt caacgcactc tacggaggcg taaaaagatt
     2761 tgcagtcaat acataaaata tctcttgaag gttctttttc ataaacaaat accggatttt
     2821 gattcgccca cataacaatc acctcttcaa cacaattaga acacacgttc tctttccgtg
     2881 tcaataaaaa acagcaattt tcaaatacga gcaaaaggct cacatttgga aattgctgag
     2941 aggttatttt tatctatttg tttttagctg agatcgttga tttttttatc aaacatgaac
     3001 agcttctgga tcgatctttg ttgtcccatt tccaatgtgt gcaacataaa attccggagc
     3061 atagccgaca actttcatgt attcatcata gacattgttt ttgaaggcag gtatattttc
     3121 ttctttgaca agagcaatcg cacagccacc aaatccagct cctgtcattc gtgcacctaa
     3181 gacaccttct tgtttttgag cagcatctac tagtgtatct aattcgatcc cagttacttc
     3241 ataatcatag cgaagagagt ggtgagaatc atttaacagt tgaccaaatg cttctaagtt
     3301 cccagcttct aattcagctt ttgccttcaa agtccgctga ttttcagaaa cggcatggcg
     3361 agctctgcgt atcaatgtat catcgccgat ttggtcaata gttgattcaa attcttcttc
     3421 atctaagtct cctaaagaag agataggcaa agttttttgc aaacgtgcca aggcttcttc
     3481 gcattcgcta cggcgttcat tgtattttga atctgccaat tcccgccgct tattcgtatt
     3541 catgatgacg attgcataac catctagttt cactggaacc atttcgtatt tcagcgtatt
     3601 tgtatctaat aagattgcat gatctagctc accgaagccg atggcaaact gatccatgat
     3661 acctgaattg acaccgatga attcattttc tactttttta cctgtttgga ctagttccaa
     3721 gcgatctgtt tttaaatcaa acagatcttc taatacaaca cctactaata attctaatga
     3781 agcgctactg gaaagtcctg caccattagg gattgttcct tccactaata actcaaaccc
     3841 atgatcgatt gagtgtccag cttcttttaa tttaaggacc attcctttta cgtaatttgc
     3901 ccagtttgct tttttatcat attctagctc atctaaagta aaactaatga caccgatatc
     3961 gtcaaagttt gtggaataaa ctaatatttt attatcgtct cgaggtgctg ctacaccttg
     4021 cgttccataa gtgatggaag cggggaagac atggcctcca ttgtaatctg tgtgttcacc
     4081 aatcaaattg atgcgtcctg gtgagaagta ttgtgtagtt tttttaggtc cgaatgtttc
     4141 ggcaaatttt gtgtttaagc ttcttttgat ttccatgatg agttattcct ttcttgtttt
     4201 gattttgaat tctgttactg tttcaaatac tgatccggct tttaaatgaa tcgaaccaaa
     4261 tgctgagaag cgctctgcac ctggagctgt ttgagtctca aatgtgatgc caccgtgatg
     4321 tgccagtttt cggttgcgca tttctggtgt ttctgtgccg aaatttgcag tgaaaataac
     4381 cacactagaa gcatctgtag caatatctac ttggattctt ttatcggggc tagtcaagcg
     4441 agcggcttct ttacccaagc cggtttcttt taagaaaaat ggatgatcga ttccgtcaac
     4501 aagatttttt tgatccaaat cactagcaaa aacggacgct aattttttag gtatttgaaa
     4561 atcgaaagca cttcctgcag cattttcttt tacccctata ggaatactat ctgttcgcaa
     4621 aggagcataa gcttcgctat tgagccaaag ctcatgttga tcgattgact gagaagcatc
     4681 tcccgtcaag ttgaagtaaa catgatttgt cggattgaat aaagtatctt ggtcactggt
     4741 gccgcgagag gtcactcgcc agatattatc ttttgtcaaa gtatagcgga tttccacatc
     4801 cattgtacct ggaaaaccat gttctccgtc gggacttgta gtagtaaaaa tgacagaagc
     4861 ttcattttcg ccattcaaaa tgacataaga ccattttttt aattcaaatc caggagcacc
     4921 accatgcaga ttatgtccag tttttggatc tgtggctaat tggtaagttt ttccattgag
     4981 agaaaagcgg ccattttcga ttctccctgc ggtgcgaccg atagaagcac cgatatacgg
     5041 atctttttcg atatattctt cagcggtgtc aaatcccaaa actaattctc gatcatttga
     5101 ttttaaactg acgattctag cacctaaatc agagatagaa agtgctagct tgtttttgtt
     5161 ctccaaggtt atcaagtgat aaccttggcc aaaatctttt tctgtaatct tcattttcaa
     5221 gatcctttct taatgggaag gaactactgc atcgtgaagt taatcttcca ttgtatcagc
     5281 tggagccaat ttgttttcca atttctcaac gatttgtgca tgttttttct ctgtcaatgt
     5341 aatcttccaa gcaaaaataa tagcggagaa aatcatcaaa gcagcaggag catagaatgc
     5401 ataagctttg aaagtcgtta cgccatgagc agtgatatca gcagcagtag cattaccagt
     5461 catcccagaa gcgatagcga caaaccctac gatcccgtta gacaaagcac cagcgatttt
     5521 atctagtaaa gggcgaattg atagagtaac agcttcgtta cggataccat ttttccattg
     5581 accatattca acagagtctg tgatcgtcat caaagcggat aagaaaatca attgttgagg
     5641 gaagtagaac aatactagcc cgatgataac gattggcaaa cttgaacctg cgatcgtaaa
     5701 gaaaaagtaa gaagaaatca tcattgcgat ccctccaagg taaacgtagc gacgagagat
     5761 gacgcgtgta agcattggga atagtggaac agctactaaa ccaagtaagg cagcaactag
     5821 accaacgatc caaaattcag ttggttggcc aagtacatat ttgaagaagt agaataatac
     5881 ggcagttgtt gctgcattgg caatcgcata agcgatataa gcaagggcaa gccacatcaa
     5941 ctgatcattt tgagcaactg ctttgaacac atctttgatc ccagcttttt cattttgctg
     6001 acggatcgca gtatcgactt cttttgtgcc caaggcagtg ataatcgcag taccgcctga
     6061 aataacagca gcaatcacac cgaaccagaa ccagcctgaa gcgccttcaa tatgtttatg
     6121 agtaacaaga taggtaaaga aagtaacgat agggacaacg actagagtag taccatttgc
     6181 acctagagaa gagccgaaac gagcaaacgt agcaaatttt tcacgttcct ttgtttccgt
     6241 actcaaagct ggaatcattg accaaaaagc gatatcctta aatgaataaa aactatccaa
     6301 taagatgaaa acgattgcaa ataatatgat aaataaagtc gtattatgag tagctaagcc
     6361 aaagaaattg gtaaagattg ctaccaagag tacggaacta acaacgccgc cgataactaa
     6421 ccatggtttg aatttaccgt attttgtacg agtattatcg atgatgccac caatcaaagg
     6481 atcaaaaata atttcaacta agcggatacc tacaactaag cttgtaactg tagcaatcat
     6541 ttttgcattc gttgccttat ctgttcctgc gaacatctgg cttgtcacga ataccataaa
     6601 ataagtgctt aatgtaacat agaatgtgtc gtgtccaaaa gcgcctaaag cgtaggacac
     6661 acgttggatc attttgcttt tcataatctg tattcctctc ctgttcaata tataatacta
     6721 agtaaaccgg ttacaacgaa taacaaagat cttttaatga cttaaactta acaagaaatc
     6781 gcttcctttt taatatattt ctgtgacttt tatttaactt tttgttgcat tatactaaag
     6841 gagtaaggag ggatagacgt ggagcaatcg atttttttaa aaaaggaaca tcaacaagta
     6901 gaaaaagaat tgtattttga tttttgtggt ttctctaaaa cgatgccgtt tcattctttt
     6961 ggtcctgcta ttcgcaatga ttacatcctg catgtcgtga tggaaggcaa aggatcttat
     7021 catgtgaaaa atcaacaatt ccaattgaaa aaaggtgatc tgttcttgat tcgtccagga
     7081 gactcgacgt tttacttatc agatggagaa gatccgtgga tgtattgctg gctttcattt
     7141 ggtgggagtg ctgcagaaga aatcattcgg cagtcgcttt tcagagaaga ccaatacacg
     7201 atggtctctt ctgacataca aaaatatatc gacattattt tagaatgcat gaaagatacg
     7261 gaagaaacct tggaaaatga attacagtta acagcattaa cctaccgttt tttatcagtc
     7321 cttttaaaag atggcggaaa ggtcagcggt ggtgtacaaa aggttcattc ctctttagct
     7381 gttgaaacag tcaaatacat cgaggcacat tatgctgaaa aattgtctgt tgaggaaatc
     7441 gcccagcatt tagcggtcaa tcggagccat ttgtcgcgag tattcaaaaa tcatatgggt
     7501 accagtatca aggaatattt gatcggggta cggatcaatc gaggggcgtt tcttctttct
     7561 ctgacggatg aatccgtgga aagtattgcc tatcaagtag ggttcaatag tctagtcgta
     7621 tttagccgaa tgttcaaaaa gagtaccgga gaaacggcta cgaactatcg taaacgtatg
     7681 aaaaacgaaa attttaagaa tattgctttg gataccttga aaaaacagtt ggaaaaacaa
     7741 accgcagttt cttggacaac ctgattagtc tggttaaaat gacaagcatc ggcaaaagaa
     7801 acttgtggcg gttatgctac actgtaaagc gaagactaaa aaggaggaaa agggatgcgt
     7861 acacttatca tcattagcca tccaacgatc gaagaatctt taaatcagca atttttcaaa
     7921 gaagcttctg ctggtttacc agctacttgg catcatttgg aatcaagtta tccagacgga
     7981 aaaatagata tagagactga actacagctc ttggcccagc atgatcggat cattttccag
     8041 tttccgtttt actggtatag ttctcctgct catttaaaaa tttggcaaga taatgtcttg
     8101 gaacgagcag cacatgtatt aaaagggaaa gaactaggaa tcgtattgac aacaggtgtg
     8161 gcggaaaaag aataccaagc tggaggaaaa gaagaatata cgatttccga atttttgagg
     8221 ccgtatcagc gaatcgcaaa taaattccat atgacctatc ttccgccatt cgttttagca
     8281 caatttatgt atttatccca ggaaaaacgt tgggagaagc taattgctta tcagcagtat
     8341 ctctcattgg aaggcaaacc atcgctgact cagcggattg actggtttat tcaaagagta
     8401 caggaaaatc agaaaatgca ggaagaagaa tctgaaaaac aagcatatat cgtagaagca
     8461 ctgactgagg caaaagagca gatcgaagac ttgaccttta cactgcaaga aatgaaagga
     8521 acttcattat gacaaatgat tggctgatcc aacaattaga tgaattaagc gaaaaatcag
     8581 aatatcaaga ccgtgcgctc ttatatgaaa taaagaaact gatggctgag atagacgaac
     8641 gaacaatgca gctgcaagga gaaatcgacg gacaatcttg gaatcatctc aactggtgaa
     8701 attttcttat aaataacaaa gataaaaatg tgcacagcga caattatttg ctacaataag
     8761 aatatgaagc gtttgataac gctattatac ataaaaattg gtggtgaaaa aaatgtatga
     8821 tgaaaatgag tggggagaaa atgttcggat gacccgaaga agacagcaaa aacaggcagc
     8881 tcgtaagcgg atgatcatga ttggggcagc agttgccgtg tttttgatca tagcaggagg
     8941 agttgcgggt ctatattttc atggaaaaaa ttcgtcagaa gcgaaaagta cgaccataac
     9001 ggaaacaacg acaaagaaaa cagagacgaa acaaacaagt gagtcatcaa ctaaaacaaa
     9061 agagacacaa acttctgaag aaaaaacagc aaatggtttg ccagagcaac ttcaagcaat
     9121 cgtaaatgat tattcgaaaa agatcgaaga aaagacgcct gcattgattg aagaatacca
     9181 gacagaaatt cagggaaatc aagagggaat agctggttta tcagcagttg ctaaccaaaa
     9241 agcacgtgag cttcaagcaa tctccgacga agggatcaga aaattacgtg cagcgtatca
     9301 ggcagcagaa aataaagacg gtgtagactt agatactttg atcaatcaat tatcggctaa
     9361 ttatacgaat catgtcgcta agatttccga tatttatttg cagactagcg cctctcttca
     9421 agcagagtca acaagcacac aagacacaac atcttctgat tctgagacag cagagtcggt
     9481 agaagcttct gaaatgcaag ctcgaacaac acaagacaca acagattcct ctgaaactaa
     9541 taccaacagc gcgacttcac aggctgcgac aaccgtagtt ttggaaggag aaggtccaaa
     9601 tcaaatagcc gaacgaactg gcgtaccagt agaaacgatc ttgtcgctga atgggatgag
     9661 catggagaat tatttcctga ctcccggtga gacgctaaaa ttgaattgat aaaagcaata
     9721 aaaaagaacg aagcttccac taaggtgaag cttcgttctt tttttatttt ccggttcttt
     9781 tttcgcgtac aaagtaatgg atcgtcatgt aaagcaagaa aacgagtcca ataatcaatg
     9841 agattctcgt ttcaggattg ataaacatga aaatcaatac gatagctaaa aaagcaagtg
     9901 tcacataatt cgtataagga gatagtggca ttttaaaagg atgatcatgc attttatctg
     9961 cgtgcttctt tttgaagcga atctcgctga tcaaaatcac tacccaagga accataccag
    10021 gcaaaatact tgagctgtat acgaaaacga aaatattttc tgactggttg atgaacattg
    10081 gtagaagata atttaagatc agaccaatta agattccacc tgagattgct acgacaggat
    10141 aaaaaggcgc accgtgacga gatagtttca gaaatttttt agacatcttt ccatttatgg
    10201 caagtgtata gaccatacga cttgcgctga aaatccctga attgcaacct gataatgccg
    10261 ctgtaatcac gacaaaatta atcagtcctg cagcaaatgt aatgccgact ttagaaaaag
    10321 tttgtacaaa aggtgaacca atctcactca attgattcca cggatagata ctcacaatga
    10381 taaaaatagc accaatataa aaaatcaaga ttcgaccgat agtggactgg acagcttcaa
    10441 tgatcgtctt tttaggattc tctgcttcac cagcagtcat tccgatcagt tcgattcctt
    10501 gataggaagc aacaacgatc gataatgcaa agaaaaatcc tttgacgcct ccagtgaaga
    10561 atccaccatt tttccaaaga tttgaaatcc ctactgcctg accatgatta ccaaatccaa
    10621 ataagattac cccaagacct gcaatgatca tcaaaatgat cgttatgact ttgatgatcg
    10681 aaaaccaaaa ttctaattcg ccaaacgcct tgacagaaat aagatttgcc agcataagaa
    10741 acaagacgac aatgattccg ggaataattg ccggcaaatc aggccaccaa taattcatat
    10801 aagatcctac agcaatcact tcacttattc ctacgacaat atattgaaaa atattactcc
    10861 aagcggtcaa gtagccagcc acaggatgga tgtactcgct cgcgtaattt gcaaaagaac
    10921 cagtcgaagg atcaacgtaa agcatttcgc ctaaagcacg cataatcaaa tacaaaaaga
    10981 atcctgcaat cgcataggct cccatcactg agggccctgt ccaacgtatg gttgaggagg
    11041 cacccataaa cagaccgaca ccgatcgttc cacctagtgc gatcatttgg atatgacggg
    11101 cactaagact tcgagttaac ttttcttctt ccatacaaaa actcctttcg ttgttgagtc
    11161 aacaagaaaa aataatcaaa cgtttcaaca catgtttttc attattaggt tagccttatt
    11221 gaactcttga tgtgattcta cagaaaattt tcataaaatg cgaggaaaat tcgaaaaaaa
    11281 ctttttcatc attctacttg aaaatgcttt ccattttagt taaactatat ttaaataaaa
    11341 agttaggtaa acctaaaaag gagtgtaaga tttggaacgt acggccattg taattcaaga
    11401 cctttcagcc gcttatcaag ggaaaactgt tttgaaaact atcaacttga cgataaatcc
    11461 acaaaaaatt accggtatta tcggaccaaa cggtgcagga aaatcaacat ttatgaaatc
    11521 tttgctagag ttgataccag ctactactgg taaagtcacc ttttctggac agtcggtaaa
    11581 ctcagtccgt aaaaaaatag cctacgtgga acagcgaagt gaattggatc tttcctttcc
    11641 aattgatgta ttaggcgttg tacttttagg aacatatcca tctttacgaa ttggacaaag
    11701 acctgggaaa aaagaaaaag aacgtgcaag acaagctttg aaaaaagtag ggatggaaga
    11761 atatgccaaa agacagatca gcgaactatc gggtggacag cttcagagag tttttattgc
    11821 aagagctcta gcccaaggag cagaatggat ctttttagat gaaccattcg tagggattga
    11881 tgcgttaagt gaacgaaaga tctttgacat cttgcaggaa ttgaagaatt caggaaaaac
    11941 gattttgatc gtccatcatg atcttcataa agtagaagaa tatttcgatg aggttattct
    12001 tttaaataaa cagctgatcg cttccggtcc agtacaagaa gtctttacat cgaagaacct
    12061 tcaattggcc tatggtgaga tcatcagaca tttagtaaaa ggaggagaga aaaaatgatc
    12121 caatccttta ttgatggatt aatgaattat caattcctgc aatacgcttt ggtcacttcc
    12181 atgcttgtag gacttgcttc tggagtcatc ggttctttta ttattttacg agggatgtct
    12241 ttgatgggag acgctatctc tcacgcagtt cttccaggtg tagccatttc ttatatgttt
    12301 ggttttagtt acatctttgg agccactgct tttgggatgc taacagcagc agtgattggt
    12361 ttcgtgactc agcggagccg attgaaaaat gatacagcga ttggaattgt ctttagctcc
    12421 ttttttgcat tagggattat cttgatttca tatgcccaga gtgcgacaga tttgtatcat
    12481 attttatttg ggaatgtctt agctgttagg gaaagcgatt tgttgctgac agcactcgtt
    12541 agtggaatcg tcttgatatt tgtctttttc ttttataaag aattgaagat cacatcattc
    12601 gatccgacaa tggcaaaagc ttatgggctg aacacatcgc tgatccatta tcttttgatg
    12661 ttctttttga cattagtggc tgtagtcagt ttacagacag taggaacaat cttggtgatt
    12721 gccatgttga tcacaccagc cgccacggct tacttgctaa cgaaccattt actgaaaatg
    12781 atcattacag ctgcaggaat cggtatgcta agtgcagttg tcggtgtgtt tttcagttat
    12841 agttacaatt ggccatcagg agctacgatc gtgttagcat gtaccgcatt ttttatcctt
    12901 gcttttttat tttctccaac aaaaggaatt ttatttcaga aaggaagcag atagatgaaa
    12961 acaaaaaaat cactcttttt aatcttggca gttagtttct tggtattagc cggttgcgga
    13021 aagcaggctt ctgaccaagc ggatgaagga agtaaagaaa agttgtcagt cgtggctacc
    13081 aattcgatct tggcggacat ggcaaaagag gtcggaacag atcaaataga tatccacagt
    13141 atcgtaccag tcggaacaga tccgcatgaa tatgaagtac taccagaaga catcaaaaag
    13201 gcaagcgatg cagatgttat tttatacaac ggtttgaatc ttgaaacagg taacagctgg
    13261 ttcgataact tgatggaaac ggctaaaaaa gaagaaggaa aagattattt tgcagttagc
    13321 aaaaatgtag aacctcttta tttaactagc ggtgaagaac atacaaaagc agatccccat
    13381 gcttggctag acctatctaa cggaataaaa tatgtggagg aaatcgcacg tatattctct
    13441 gaaaaagatg cagaaaatgc gacactctat aaaaaaaatg cagaagcata tgtggaaaaa
    13501 ctaaaagaat tagatacaca agcgaaggaa agttttgctt ctatcgaaga gaacaaaaaa
    13561 ttattagtaa caagtgaagg ggcattcaag tatttttcac gagcatatga tttgccagca
    13621 gcttatatat gggagatcaa tacagaaagt caaggtacgc ctgatcaaat gaaagcgatc
    13681 attgatcaga taagagcaaa agaagtaccg gttttattcg tggaaaccag tgtagactca
    13741 agaagcatgg aacgggtagc aaaagaaacg ggtttgaaaa tctatgataa actgttcact
    13801 gattccatag caaaagaagg agaacaagga gattcttact atcagatgat gaaatggaat
    13861 attgaaacga tccatgaagg tttgtcacaa acaaaagaaa gctgaaaagt gcaaggtcta
    13921 gcttgaggag cagaccttgc attttttata agagatatga aaaaaaatta tgctgttttt
    13981 cgtcgtacag ataccttttt tgaagaaatt ccgttatagt tagagtaagg aaggaaggtg
    14041 tggctatgaa ttttacacgt aaagataaat atacgattaa agaagaagtc tttcgattga
    14101 tcagccagca ggaaaatacc gacaaggatc aagaccttca atttcttgaa gcagaattag
    14161 ctaaattatt catagcaaat caaaatgaga caacagaacc agatgaagag ctgtacatag
    14221 gcaaatggtt gtttgatgaa tttcagcctt tagatgaaaa taccggtatc ggttattttg
    14281 tgttcctttc tccagtcggc ttcacacctg gcgtattagt taaacaaaac gacgaaataa
    14341 ccgtcaaagc atggcctgca ttattttcag tcatcaaagc agaaggagta atcaaaaaga
    14401 tccagtcggc ctattataaa agtcaattta ttgccaacag caaattaatg aatatgtttt
    14461 ataatcgtct agtagaaatt gctaggcctg ggaaaatccc gcaaacattc acgtacacac
    14521 agcaaaaaaa tctctatgaa gaagtattgt attcccgcga tctgtctgag ttttcgccat
    14581 gggaagaggt aaggctccat gaactgttaa gtacaaaacc agtttcattg aattttttta
    14641 atgcattaga taacaaaaga aaattaattt caacaaatta ttgggaagta tttgctgcaa
    14701 gaaaaaaatg gatggaagaa aagaagattg ccgatcagca gatccagttt gtccagctga
    14761 aaaaagaaaa actatattat gggttataca gccgttaaca gcaagcgagg aagaccatga
    14821 cattaaaaga agaaatcata caagaaagca aacgattagg aattgacaaa atcgggttca
    14881 ccacggcgga accttttgat tcattaaaag aatcgttgga agaacaaaaa gcagctggcc
    14941 atacttctgg ctttgaacat ccaaatatcg atgagcgtct ttatccagaa atgacatttg
    15001 atcagccgaa atcgatcatt tccattgcac ttgcgtatcc tactaggatc catgaagaag
    15061 tgcctaggga tgaaaaacgc gggcagtttg ctcgtgcttc ttgggggatc gattaccatg
    15121 atatactcag agaccgtttg aaccgattga tcgaattcat ccaaacaaga gcagaaaaat
    15181 ggcaaaaaga agaggaatgg cgtctagctc cgcaagtaga tactggagaa ctgatcgatg
    15241 tcgctgtagc acagcgagct ggtttaggat ttattggacg aaacggattg ttgatcactg
    15301 aagagttcgg ttcatttgtc tatcttggtg agatcgttac taatattgta tttgagcctg
    15361 ataaaccagg agaatttggt tgcggtgact gtatgcgctg cgtgactgct tgtccgacaa
    15421 aagcattgct tggtgacgga agaatgaatg cccagcgatg tttgtcttat caaactcaga
    15481 caaaagggat gatgccggaa gaatatcgta aaaaaatgcg aaatgtcatt tatggatgtg
    15541 atatctgcca gttagtctgc ccttacaatc aaggaaaaga ttttcatttt catgaagaga
    15601 tggaaccaaa agtagacgaa atatatccaa aattaaagcc aatgctttcg atgtctaata
    15661 aagacttcaa acagcaattt gggcatttag ctggttcatg gcgtgggaag aaacctttgc
    15721 agagaaacgc attgattgct ttagctaatc taggtgatcg aacggcattg cctgagattt
    15781 cagaatgttt aacagatgtc cgccctgtca tcagaggaac agcagcttgg gctattggac
    15841 gtctaggaac aaaagaaccg gaaaaatggc ttgatgtatt agatgaaata ttagctaaag
    15901 aaacagaaga agtcgttata aacgaattgg aacatgccca gaaattattg cggagaaagt
    15961 taaaataaaa aaatagttaa cattattcaa agtttttgtc cagtaattgt tgtaacaatt
    16021 actggttttt ttgtattttt ta
//
LOCUS       DADVXV010000068        15801 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.069, whole genome shotgun sequence.
ACCESSION   DADVXV010000068 DADVXV010000000
VERSION     DADVXV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15801
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.069"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..275)
                     /locus_tag="KB969_002073"
     CDS             complement(<1..275)
                     /locus_tag="KB969_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6870040.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFY"
     gene            499..1290
                     /locus_tag="KB969_002074"
     CDS             499..1290
                     /locus_tag="KB969_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6870041.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1256..2209
                     /locus_tag="KB969_002075"
     CDS             1256..2209
                     /locus_tag="KB969_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBB6870042.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2607..3581)
                     /locus_tag="KB969_002076"
     CDS             complement(2607..3581)
                     /locus_tag="KB969_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6870043.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YHAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3696..4130
                     /locus_tag="KB969_002077"
     CDS             3696..4130
                     /locus_tag="KB969_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6870044.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4255..5277)
                     /locus_tag="KB969_002078"
     CDS             complement(4255..5277)
                     /locus_tag="KB969_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HBB6870045.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5669..6091
                     /gene="arsC"
                     /locus_tag="KB969_002079"
     CDS             5669..6091
                     /gene="arsC"
                     /locus_tag="KB969_002079"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HBB6870046.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHGLN
                     PRAIKIMAEDGIDISKQTSDLIDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDL
                     KDPAQAVGSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
     gene            complement(6371..8293)
                     /locus_tag="KB969_002080"
     CDS             complement(6371..8293)
                     /locus_tag="KB969_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBB6870047.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(8380..10320)
                     /locus_tag="KB969_002081"
     CDS             complement(8380..10320)
                     /locus_tag="KB969_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBB6870048.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            complement(10608..11348)
                     /locus_tag="KB969_002082"
     CDS             complement(10608..11348)
                     /locus_tag="KB969_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBB6870049.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
     gene            complement(11361..12452)
                     /locus_tag="KB969_002083"
     CDS             complement(11361..12452)
                     /locus_tag="KB969_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBB6870050.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            complement(12442..13548)
                     /locus_tag="KB969_002084"
     CDS             complement(12442..13548)
                     /locus_tag="KB969_002084"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBB6870051.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            complement(13567..14229)
                     /locus_tag="KB969_002085"
     CDS             complement(13567..14229)
                     /locus_tag="KB969_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HBB6870052.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAIFPA
                     VN"
     gene            complement(14240..15019)
                     /locus_tag="KB969_002086"
     CDS             complement(14240..15019)
                     /locus_tag="KB969_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HBB6870053.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            complement(15048..15398)
                     /locus_tag="KB969_002087"
     CDS             complement(15048..15398)
                     /locus_tag="KB969_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HBB6870054.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            complement(15414..15770)
                     /locus_tag="KB969_002088"
     CDS             complement(15414..15770)
                     /locus_tag="KB969_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HBB6870055.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
BASE COUNT         4694 a         3316 c         2668 g         5123 t
ORIGIN      
        1 tgataaaaat aaattgggtt cttcagctgc ataacaaaaa caaatggctt ttcgacatat
       61 tcacattccg aatgtggcag cgcgatattt aaatacttag taatcaatcc agtaggaaat
      121 tctctttctc ttgcaatcag tccattcaaa taattctcat tgacgtaccc cattttttct
      181 aattgttgtg cagcgattaa aaaagcttct tctttatttt ttacttctac cgctaattga
      241 atcaaactag gaacgaacat ctctttatat ttcattccaa cctcctcctt tttgattaag
      301 tttgttaatt tattgttcta ctaaattcat ctttgtttta caagaacatt atatttctgt
      361 tagtttgttt tgtcaacgct ttcaaaagaa atttattttg ttaaatttga tctacttgaa
      421 aataaaatcg tttatctata taattaagaa gaacaaagtc gaacaaaaat tgacttttat
      481 gttaaaggag taattcatat gctgaaaaaa gaaagacaag aacaaatcat tacattatta
      541 gagaaagatt tttatttaac taattcagaa atcgctaaca aattaggcgt atcagaaatg
      601 accatacgcc gagatgtcac tgaattagca aaaaaaaata aagtaaaaaa gctatatggt
      661 ggcgttgaac gaaaggaacc ttataatcga gaactatcga ctcaagaaaa gattgatacg
      721 aatgtagccg aaaaaaaata tattggtcaa gtcatgaaca gtatgattcc cgataattct
      781 actatttatg tcggtgctgg aacaacgatc ctatatgcac ttcctttcat tcaaaagaaa
      841 aatctatttg taattacaaa cagtttgatt gctttcaact atttaaagaa tcatacaagt
      901 tatcggattt tacttactgg tggcgaattt tctcctatta cagaagagtt cattggggaa
      961 gttgcagaaa gatcttttga aagtttgaat gtcgatatct ctttcgctgc aacaaacggc
     1021 atatttgata acaatgtgac aaccgctcaa tttattgagg gaaatattca gaacgcagcg
     1081 ctcaatgcag caaaaatcaa atgcattgtt gcagattatt caaaattaaa taaatcagac
     1141 gtctatactt ttagaaaatt aaccgatttt gattatctaa taaccgataa tcatttatca
     1201 gaacaggatt tcaatcatta ttcaaaatac ttaacaatat taaaggagcc caaaaatgat
     1261 actgacaatc acgatgaacc catccattga ttccatttat tttacaaaac actttgaatt
     1321 aggtacgatg acacgctttg attctccggt acgctatgta ggcggcaagg gaatcaattg
     1381 cggacgagct tctgctctac taggttcatc agttatttta acagggtttt tgggcggtta
     1441 ttttggcagt atgattcaag atatgctgaa aaatgaaaat ttgtttgatt tgcatttttt
     1501 acctattgca gaagaatcaa gaggtgccgt cacgatcatg catgatgatg aaacgcagac
     1561 agagctagtg gaagctggtc ctgaaatagc agatactact atcaaaaaat taatgaatga
     1621 tatcaaacta atcagtaaaa ataattacct ttcagtcatt acaataaatg gttctgttaa
     1681 caatccagat ccctttttgt atgctaaatt attacaatat atcaaagaac aaatagatcc
     1741 ttccacctat atattaatgg atatatctgg acaacatctc cgtgaagtct tagcaagtaa
     1801 gtataaaccg atgttcatca aacctaatat ccatgagttt tcagatatca tccatcaaaa
     1861 aattactcaa aaaagcgaca taaaacacca tctaaaaaca aatccactat ttaaagatat
     1921 cgatgttatc atgatttctt gcggctcgta tggtgcagta gtcaaagtaa aagaagaatt
     1981 ttggaatgtt gagatcccta agattcctat cattaataca acaggctctg gggatgccac
     2041 tgttggaggt tttgctcatt cattagaaca gaattatcct ttaaaagaat gtgtaaggta
     2101 cgcaatggct tgcggcatgt cgaatgcaca gcaatcagaa gtcgggaaag ttattccagc
     2161 tgatgtaaaa aatttagcaa aaagcattaa aatcacagaa atgaaataaa tagtacaaag
     2221 taaataattg tttatatgaa atgagacaca aagagactgt gacaaaaaac gtgtgtaccg
     2281 acccccaaaa gttagatttt ttggtctaac ttttgggagt cgatacattg tcacagtcct
     2341 tttttcgaat aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atattcaaca
     2401 aacatgagaa gctatttttt gaaattgctc cttgtgactc agagttaaac ggcaggctca
     2461 cgacctcttg gtataaacgg tgttcaaaag cttgcatcta cgctaatgag tccaaccaag
     2521 tcaaaaatga ggagcttttt tggctgtcct tattacttga tgcagggcag ttttttcata
     2581 atctctttta gattaaatcc ttttggttac acaaggttct cttcaaagaa tgttgccatt
     2641 ttttcaaatg gaatgatgtc tgtctggtcg tatagatctg tatgggatgc tcctggaatg
     2701 atcatgagtt ccttgttgtc accttttagt tctttgaaag cgtcctcccc aaagtaacgt
     2761 gaatgagctt tttccccgtg aatgactaag actgcatgac ggatttctgg aatataatgc
     2821 aatagttttg cattcataag tgacaaccct gatgtcctat tccaaccatc attggagttt
     2881 aaagaacgga catgatatcc gcggtctgtt ttataatacg catgatagtc tttgacaaat
     2941 tgaggagcat cttcaggcaa cggatcaacc acacctccag cacgtgcgta gtccccttgt
     3001 ttgaaatcaa tgatgcgttg tgcatttaat tcttcacgca tttcatatcg ggcattttca
     3061 tccataacat cgaagtagcc atttgctgtt actcgagtca tgtcatacat tgtggaaaca
     3121 actgttgctt tgacccgcgt atcgatagct gctgcattca atgccatacc tccccatcca
     3181 caaataccaa tgattccgat tctctcaggg tttacatttt tttgtacaga taaaaagtct
     3241 actgccgctt ggaaatcttc cgtattgata tcaggcgaag caacatatcg aggtactcct
     3301 ccgctttctc ctgtaaacga tggatcaaac gcaatcgtta aaaagcctct ttcagccatc
     3361 gtctgcgcat atagaccaga cgattgttcc ttcactgcac caaatggccc gctcacagcg
     3421 attgccggca atttcttttc acttacttct tttggttcat ataaatcagc gactaatgtg
     3481 ataccaaaac gattcgggaa gctcaccttt cgatgattga cttgattgct ttttggaaat
     3541 actttgtccc attcttgtgt gatgtttaat tctttattca tattctagac tctcctttga
     3601 tcaaaattga catttgtttt tgaatgtatt attatgataa aacttaaact tgactttagg
     3661 tcaaggtaaa aattttattt taggaggatt tttttatgta ttccattgga caagtgtctg
     3721 aaatgtttgg attgcctgtt tctactttac gttattacga caaagaggga ttatttcctg
     3781 atatccagcg tgtttctggt attagaaaat tttcagagaa tgagttagag gctttaagag
     3841 tcattgactg tttgaaaaaa tctggtttag aaataaaaga cattaagcaa ttcatggaat
     3901 ggagcaaaga aggcagtaag acatttgagg ttcgtaaaga actatttgaa aaacaaaaag
     3961 aagtagtaga aaaagaaata gcaaaattag aaagagtact cgctatgcta aactacaaaa
     4021 gctggtacta tgaagaagca ataaaagccg gcaatgaaga agccgtattg acaatgattc
     4081 ctgatgattt accccaacat gtaaaagaag cttatgtaca ttctcattga acaaacggat
     4141 aactcactct ccttctctat gaacttcatg aaaacatgaa taaacacctc taactgattg
     4201 ttagaagtgt ttattttttc actcaagtat cctgcactta caaaaatatc ctttttaccg
     4261 ccatcctaat tctggagcga tatcttttac gattgtttca agcaagtgca tgttatattc
     4321 tacccccaaa gtattaggaa tcgtgacaag tactgtgtct gcttctttga ttgcttcatc
     4381 ttcagctagc tccttgatta attgatcagg ttcaccagca aaagtttttc caaaaatcgt
     4441 tgggtttcgg tgataagcaa gatagccgac agcatcttgt tgcggactac cgtcttgtcc
     4501 aaataagcgt cgatccaaat cagtggtgat tggctgaatc gagcgagtaa ctaatgttct
     4561 tggttcaaaa tcatgacctg cttgcttcca cgcttcttta tacgcacgta attggtttgc
     4621 ttgttggata tggaatggct cgtgggattc gtaattgact aatgtagatg attgcagatt
     4681 cattccatgt tgtgctgccc agattgccgt ttgctgcgaa ccagctcccc accagattct
     4741 ttgtcgtaat ccttctgaat aaggttctat ccgtaatttt cctgatcctt gtgggaacat
     4801 tggttgagga tttggttctt caaatggttt tccttcaagt aattccaaga attcaagggt
     4861 gcgttcccgt gttacctctt tgatttcttc ttcactgtaa tcataaccaa agtatttcca
     4921 gccatctaga acttgttcag gtgaaccacg ccccactcct agttgcactc ttccttgcgt
     4981 gatgatatct gtcaatccgg cattttctgc catataataa gggttttcat atcgcatatc
     5041 aataagtcct gtaccgattt caatcttact tgtctttgcg ccgattgccg ctagcaaagg
     5101 aaacggcgac ccaatctgag gggcaaaatg atgtacgcgg aaaaacgctc cgtccactcc
     5161 gattttttct gcttccaccg ctaaatcaat cgattgcaaa taagcatctt gagctgattt
     5221 cacaagcgat ccttgctcca tccaatgtcc aaagcttaaa aagccgattt ttttcaaggt
     5281 aatgacctcc tttaaaccta caaaaatgga aggtttttta tttttaatat gaactgattc
     5341 tactactttt tttcttaaaa gacgaataat tgttctcgcc tcacaatcaa gaaatgtatc
     5401 ggcttactac acccctactt tcttcatcat ctgccgtgtc ttaatctctt ttaacagtct
     5461 gttacatcgt tgatttttga ctcaaaatga ttgtttctaa catgtattta tggtaaaaaa
     5521 gacaagatta gttctttgta cacatcgatt tatacgctga acaaaaagaa atatataaac
     5581 taagaaaccc attgtttttt cgctccatca catagagttt actttagata aacagtgaca
     5641 tttactaatc cataacggag gaaatcaaat gaaaaaaatc tatttcttat gtacgggcaa
     5701 ttcatgccgc agtcaaatag cagaaggcta cgcgcgtaaa tacttgtctc cttcaatgtt
     5761 tgagataaga agtgcgggga tcgagacaca tggcttgaat ccaagagcta taaaaatcat
     5821 ggcagaagac ggcatcgata tttccaaaca gacgtctgat ttgattgata gagattactt
     5881 tactcaggca gacttgatca ttacactttg tggtgatgcc aaagacaagt gccctgccgt
     5941 tccaaacaat cacgaacacc ttcactggga cctaaaagat cctgcacaag ctgtcgggag
     6001 cgaagaagaa atattaacgg aattcagaaa agtcagagaa ggaatcaaaa gaaaagtttt
     6061 agacttaaat caacgtacat cgatcgtata aagaagtatt caaaatgatt tttcaagcac
     6121 taagaaacaa tgttaaaaaa atagctttcc atattttaca aaattgtgcc ttattgccga
     6181 caaattgtct cttgaacacc gtttaccagt agtcaagaca tcgtaagcaa ctataaaaaa
     6241 ttataagaaa ctcaaaataa aaggatgtgc cacaactttg gccacatcct ctttttttgt
     6301 atttagtttt ctacttccaa ataaatagat agaattatta taaatataaa ggcagttttt
     6361 taatcgctac ttattcataa ctagataaca acgttaagat ttctagcgga tgattggatt
     6421 gcatcaactg agccatttgt tctggctgct tttctagata gtgaataaca gaaaatattt
     6481 ttttgaactc tgcatgtttc aaatcatttt tctttattgc taatagcagt acgatacgta
     6541 tctgttcccc gtgccatagg actggttctt tcattgtagc aatagaaatc atcgaatgct
     6601 tcacatacag cggattaccg tgagggattg ttacaaatgg tgctactcta gtactggagt
     6661 gactgtctct ttccaagaca gaatcgatga attccggctc cacataatga tgttccacta
     6721 agacgtttcc cataaagttt aaaatatcgg ctgggtctgt ccgttcaagt tgaggaaaga
     6781 tcagaaatgg atgagtaaag cttgctagat caaatgtttt tttcttcttg ataggcacat
     6841 gctccagcat atattttgtc aaataggcta gatcagtttc tgtgatcatt ggtgagatct
     6901 cgattactgg aatgcttata tgtttaaatg gtaacgtagc caagataaaa tcaacagagg
     6961 gaaaatcttg tctctttaat tctggcttat attcaactag atccataatc gttaattctg
     7021 gaagttctct gttcagccgt gcttcgagaa aagtagccat agcttttgaa tattcactaa
     7081 ctaaaaccgt ttgatatctt ctacttttct gatgtttgtg tcgctcgatc gctgcttgga
     7141 aatggatcgt taaataagct gtctcctctt gtggaacata aaaattttcc ttttcaaaat
     7201 aatcttctaa aattaactgt aaaactaaga aaagttgtgt gtacgtacta aacacatttt
     7261 tcgtcaatgg attagaaatc tgcaaaccat aatggagtcg aaaataagtt gaagataaat
     7321 gagaccttaa attttgtttt agtagctgat cttcttttaa tgaatagcct agaaactgtt
     7381 ccacttgttc gatcaaatga tcagcaagtg cgctagattc cttttgaaaa cgtgtggctg
     7441 cttgtgaatt tgtaaaaaga ttggcgatac gcaaagccag ataattgatt tcatcaggag
     7501 aaaattcaat tggatagatg gtggctagtt ttgctaatat ttgactactt aacttttgtg
     7561 cttgggtgtg ttccacgact tcgttttcgt ctttacttaa tttcactttc tggtactgtt
     7621 tcattcgctc gagcataaag tagatgtgaa tctccacact agccagtcca ttcggctgtt
     7681 ctaaatggtt ttcataaaaa acatcttgta atgtatgttg gataactttt aatgtatctt
     7741 tagcgaagaa ttctttcaac gacggacttt gtggatcttc tttctgcata tttcgtaatg
     7801 tcttaacaag caactgtctt ttttcttgtt catcgccttt aagaaaagtt cctagttttg
     7861 ttttggatac tagctgtaaa tggtgatact caaaaaagct ttgcaactct gtcaattctt
     7921 tacgaatcgt acgttttcca acatatagtt tttctgaaag ttcttcaaga ctaaatccgt
     7981 cttttgctac tagcagatgg aaaatcaata actgacgaag ctgtttttta tccatttctg
     8041 tttgagtctc ttcattaagc gctcgtttca gttgttccct ttcgtgaggc agaccattca
     8101 acaagatacc tgtacctttt tttctttcaa acattaaagg cagatgtttg tctctcaacc
     8161 aagtttcaat ggtattcaaa tcgctatgaa tcgttctttc tgacacatgg aaatgctctg
     8221 ctagcttttt tgttgttata taattattgt tctcacttaa ttgatagatc aaagattgct
     8281 gacgctgatt cataatgtgc agaaactccc ttctaaataa aaaatcgatc atgataacac
     8341 atctattatg tctcatcacg gtcgattttt catcttatgt tacatttcgc ttaataattg
     8401 gtgaactgtt gttttatctg gcgcttccat cagtgcttga cggaagtcat catccatcaa
     8461 tttacgtgat agacgttgca gtattttcaa gtgcatatca ccttggctgt tttcaggtac
     8521 agcaatcata aagatcatat gtgcaggttt tccatctaaa gaatgccaat ctaccccaga
     8581 ttgacttctg gcaaatgcca ctgttggttt aagaacataa gctgattttc catgtggaat
     8641 agcaatcccc ataccgattc ccgttgtact ttcatgttct ctatcataga tgacttcttt
     8701 aaatctggtt ttatctgtga tcgccgctgt tttttctaaa cgttggacta aatcttcgat
     8761 tactccgtct tttgttgttg ctgtttcacc taaaacgatt gcttcatctg acataatatc
     8821 cgtgatagaa tcaaaagttt cagttttcgt ataaacatca cttgtttcag tctctgatag
     8881 atctgctact gtcacaccat ttgctgcagc aaccgcagtt tgttgtaatg tcggtttaag
     8941 gattcttaac attagcacgg ttacagcaat accagcaatc actgctacaa aaaacatggc
     9001 tacgtgatcc actgctccta aaaccgctac gatcggaccg ccatgagcta catgatctgt
     9061 cactcctgaa agcatcgcga tcacacttcc tgtcattgcc ccgattacaa tgcttggaat
     9121 cacccgtagt ggatctgttg aagcaaacgg aatagcgcct tctgtaatcc caaacagtcc
     9181 cattgctaag gacgccttac cagcttctcg ttctgttttc gtaaatttgg tttttaaaat
     9241 caatgatgcc agccccaatg ctaatggagg gatacagata gctacagcaa ttggccccat
     9301 aatggaataa ttgccttctg caatcaagcc agatccgaac aaaaaggcta ctttattgaa
     9361 cggccccccc atatcaaaag caatcatcgc tcctaagatc atagctagaa caatttcact
     9421 tcctccttgc atccctgcta aaaagtgagt caatgaacta aatagaagag ctactggttc
     9481 tccaataaca tagataaaca caaaaccaac tgccaatgat cctaaaattg ggataacaat
     9541 aattggcatg atcgattgta aagctttcgg tactcgcact ttcttgattc ctaaagcaat
     9601 gaatcctgct aaaaatccag tgatgatccc gcctaagaat cccgcattcg catcactacc
     9661 atataatgct ccgtttgccg ctaacatccc accaacaaat ccaggaacaa gtcctggacg
     9721 atctgcaata ctttgcgcaa taaatgcaga tagaattgga accatcaacc ccatagcgat
     9781 acttccgata ctattcatcg ttgcccaaat cgttccttct ggtatcttga tcccttcagg
     9841 tgtagctgtt cctcctaatg ttaaagaaat cgcgatcaat aaccctcctg taactacgaa
     9901 aggtaccatg tacgaaacgc cattcatcaa actcttatag atttttttac ctaaattttc
     9961 tgattcactt ttattttcgg aagaaataat tgcctccgta cttttataga ctggcgcttt
    10021 tcctgctaaa atatctctca ccaactcatc tgcatggtgg attccttctt gcacacctac
    10081 ggttatcaaa ggtttaccgc cgaatcgtga tttatctatt ttagtatctg ctgcgatgat
    10141 tacaccagct gcttcttcga tatctcttgc agtcaattca ttttcaatac cgatggaacc
    10201 atgtgtttcg acttttacct cggcgccaac tgctttcccc gctttctcta agttttctgc
    10261 tgccatgtat gtatgggcaa taccaactgg acaggatgtg attgcaataa tttttttcat
    10321 tttcctaccg cctttctaca tttatagtat ataaaaacgg tttcttttta ttaagcacaa
    10381 aatgattccg taataactga aattcttgga ataaatagaa atttcgctaa aaaaattgat
    10441 atacgattta ttatgttgaa taaaataata ttggaaaatc ttacatttct gtacttctgc
    10501 ttacgtacat ctaaattatt atctacatta acaatttccg taattaatta taaaaagctt
    10561 attccattta atttcattct ggaataagct tcttattttc taatgagtta gtgaataatt
    10621 ttttttacca tgcttaatag tatctttacg tctcctatac gcgtatctcc tgtttcttta
    10681 tctataattg aactataaac atgaggaatc acttttttta cacctgcatc gattgcaatt
    10741 ttcagaattt cttcaaagtt tgaaagatca attcctcctg ttggctctaa atagaattca
    10801 tattttgcgc aagcttccgc aactgcttta aattcttccc tatgtgctaa gcctttcatc
    10861 gggaaatact tgattgaagt acctcccatg tcttgcagca tttgaatggc agtttcaata
    10921 ggcacttcag ctgctggcgc ttgtgaactt aacggacctg tagcaatatt gacatagccg
    10981 atcttacctg ttggtgaaac caatccattg atgactgtat cattttggcc caataaagca
    11041 cgagaagtcc ccacgccagt aaatacttga ttgacatgtt gtggttgtaa aaccccagat
    11101 aaacgcgaaa ccatctgact ttggtttgga tctccagcgc ctaatccaac tgacaacgca
    11161 ttattggttg cgtcttggta ccttttcata tcttcgattg ctgcttcatc gctagcataa
    11221 tttttcgata gcacacctag tacgacatgc ccttccgctg cttcatagca tgcttttgca
    11281 ttttcaactg aatgagctaa tacatttaaa catacacgat ttttataata atttgggata
    11341 actgacaatt taaaagcctc ctacatgatt tctctcaatc tttttataat tttttccatt
    11401 tcgttttggc tgacggaacg aatgtcgaac tcaatgattc cgttatttgc ttgatattct
    11461 cgggtgtaga ctgctggatt tcgtgctttt aattcctgaa tgacttcttt cgcactttta
    11521 tcgccattaa tcgttacact tgctcgataa atatctctgc cggcaccatc ttgaactatt
    11581 ttcgctgaaa ggtcaggaag ttgattgatt gcgttaacaa aaggcgctaa tcgttgcttc
    11641 atggagtcac cggattcgct cccatttttt aaataatctt ctagtgcctg ggtaaagcct
    11701 aaaatattat ctttaccgat tttcattgct cggccaatac ctttagactg tagccgaatc
    11761 cattgaatat acttcttttt tcctatgacc agtccggcac tcggaccttc gattgctttt
    11821 gccccagagt aaatcactaa gtcaacgccc atttcgctat atttgaataa atcttcttcc
    11881 gcagctgcat caacgatcaa tggcaaacga tgagctttgg caacttctac catttctgcc
    11941 accgtcagca tacttttctg aactgcatga tgacttttaa tatatagaag cgcagcagtt
    12001 ttttccgtaa tcatcatgga aacatgttcc ggtgtacaca tatttgcata gccagcttct
    12061 atgacttttc ctccaccttg agcaaccatt acttcaaccg gtgtcccata atctacatta
    12121 tgtcccttag gtatgatgat ttcccgtcta gcgatttttt ctgtataggg atgatagaca
    12181 tggtacatgt cgccctgtcc gattaaagca gcaacagatt gagcaatccc tgctgaagca
    12241 gaagaaacga tttgcgcatc ttccactttc agtaattgag aaagataagc gccggttttg
    12301 atggcaagat cactcatctc aaaaaaatgc tcgcctccaa atcgttgtgc tgctaggaca
    12361 ctttcagata ccttagaaac ccctaggatc gtcatttttc ccgatgcatt aatgacttct
    12421 tttaaatcaa actttccata gctaattgtc atatatgacg cctccaataa ttgttttaat
    12481 cggtaaaatt tgttctttag ctatacgtgt aaatccgttg gaatctttca attccttttc
    12541 attttcaaca atctcaaata tcgtcaaatc tgcatcataa ttgacagcta actggccctt
    12601 attcttcaaa tgaaaattcc gtgcaggaac tgctgtaact ttttcaatga tttcttccca
    12661 agaatagccg actaccctca atttttctaa agtagttgct agatcaaaaa ctgggccatt
    12721 tgtacgattg cggatgtaga tatccgtact aatagaggta gctttcattc ctgcttttag
    12781 tgcggtttct gccacatgga aattaaagct atccgtccca tgtccaatat caaagacgac
    12841 accattattg taagcatccc agacaaagtt tttaatttga tctgtctttg gatctaaaat
    12901 accgtttggt tttccattaa aacaatgggt caatacatcg cctctttcca ttcttgacaa
    12961 tacttcttct aactcaggag gtgcagaacc gatatgaacc atcaatggca gatcattgtt
    13021 ttctgtctgg atttttttag ctaattctaa tggcttaatg ccattttcac caacaactgt
    13081 cttactcatt ctcgctttaa tcccgacaat aaattccggc agttctgcta acgcagtact
    13141 tactagatct tcttgaatct ttgttagatc agcaagttca tcttgtttga caatgcccca
    13201 tttagagata ttcattagcg catacacatt tgtcttgacc gatttcgtca attgataaaa
    13261 ttcacggatg ttttctgctc ccgtagttcc agcatcaatg accgtcgtca cacctttttc
    13321 gacccctatc tgatcaggat agtcataata aagattcatc ttttcatagc agtggacatg
    13381 atcatcgatc cacccagcgg ataaataata ctttccctcc aagtcaacta cttcttgcgc
    13441 cggctgattt atttctgctg caactgcttt aatcatgcct ttttctatag cgacctctat
    13501 tttagatcca tcaactaacc ttccattttt aatcaaagta tcaaacattt aatgaccctc
    13561 tttctattaa tttactgccg ggaagattgc tcctaaaata gcacctccag caattggttt
    13621 tttccaagca tagaatccta gtgctcctaa tgtagcgcca atgccgattg gaatagatgc
    13681 tgcacacgcg cttaatataa ttaatggacc caaaaaacgt ccagatgaat ttcctgcccc
    13741 catcatgacg tcagcaccaa aagtggaatt tgattgattg atcgtaaatt tacgaatcaa
    13801 gacaatgatg ccaccaacaa tcaaacctag aaccaaacca gtcaataaag agagtgcaaa
    13861 attatcgatt ggtgccgcta ttttcatact taagagaatt gctggtaccc caattccgat
    13921 cccagttagg atcgaaccgc ctaagtccaa gatcccaact aaagagcctt ctaaaattct
    13981 ggcaaataag aaactagcac caaacgctgc cgctgcgcca taggatccgc catccagccc
    14041 ggcttttaac atcgccacga tcgaaacttc attgaatgca cccacaccat acatcacata
    14101 catgtgtgtt cctgcaaata cagcagcgga cataattcct acgattagcg gaaaagacca
    14161 gtctgcaaac caaaagctct tttgccgctt tgcttctaat acttttgctt gttcttctgt
    14221 tgtctccatg attctcctcc tatttcacac taaagatgtt gtgcaagtta tcaagccaat
    14281 taggcacttg aagctggaag ctcttgatca tttccatatc aaatccacgg aaaaatccac
    14341 tgaaaataaa taataaaaca atagcgatca tcatgctctt cgtgacgcga ttccaaccgc
    14401 tctcatcgac gcctttacca atcaagattc ctagaacaac accaggtacc gcatttccca
    14461 taatcaattg cgcgatacca ccaaaaagag tgccccaaaa accagttcgt ttccctgcgt
    14521 ctaaagctgc caaccaaaaa ataactggca ttactgtatt gatcagaatc gtcgctgctg
    14581 gtaccaaaac ggaaaccgcc gtcacttgta acgcctctgg aattgctgca gctgttgtgt
    14641 ttaagaaggc taccaccact gccccgataa ccgctccaat gatccccatt tttttcggat
    14701 catgcatggt ctgggtgaca tctttgtttt ttgctagaag tgctgccgct gcccaattgg
    14761 gaatgattcg atgcgtcaca tcttgtgtga atgcaccagc accaactgaa gaagcccatg
    14821 cattaaagaa aaagcctaaa ccaaatgaaa aatgagaagc tggatcaccc atgcaggcat
    14881 tcatttcgcc taatgttcta aaagctccta aaccttgtgt attaggtgca tgaaacattc
    14941 gagctgcccc gacagatgct gcaaaaccaa gtaatccccc gataatgacc gatttgacta
    15001 gaatgattac gaaatccacg ttattctttc ccccttatga ttcaaaatta gattttttta
    15061 gttacaaatg gaatggcaat cccatttgga tcttcagtca tttgctggct gaacgatatg
    15121 tctgccaatt ttatttctgt tacagccaca gtaacagaga gttcgacttc atagctaata
    15181 cgttgccgtg ggaagaagaa aaatagaaag cgttctgtgt atttgttttc gaccgccttt
    15241 aaaatatcca cattgactgg ttcgattcgc aataatacgt ttgattgttc cattattttg
    15301 ttttgaattt ctgctaacgc tgatgcaaaa gcatgttgct ttgtttcccc tttaccggag
    15361 acgataactt tttgctgaat tgtcttttga acgctcattt catgtccctc tttctatttt
    15421 ccatgctttt tgataaattc ttctgtcaga cgtttcccta attcctcttg atccataaag
    15481 ccgaaaccta gaacagtttt gccatccttg atagctgtga tcccttcttc aatcgaacgc
    15541 ataccatgtc gttctggata gccatatttt gttgctgctg ttaatgcacc tgcaccacca
    15601 ctaccacaaa aagagatacc catatctgca tgctcttgtt gcatcacatc gcccaaacgc
    15661 atatctgccc ccattcctgg tacgacaact gcttttccac cagctgcttc tacccctttg
    15721 gccacatttt gtcctttacc catacggtct gcaataacta ctttaatcat gattgtttcc
    15781 tcctcgtaaa atatcatttg t
//
LOCUS       DADVXV010000069        15786 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.070, whole genome shotgun sequence.
ACCESSION   DADVXV010000069 DADVXV010000000
VERSION     DADVXV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.070"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(95..1138)
                     /locus_tag="KB969_002089"
     CDS             complement(95..1138)
                     /locus_tag="KB969_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBB6870056.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1515..2480)
                     /locus_tag="KB969_002090"
     CDS             complement(1515..2480)
                     /locus_tag="KB969_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBB6870057.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            2714..3559
                     /locus_tag="KB969_002091"
     CDS             2714..3559
                     /locus_tag="KB969_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6870058.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            3750..4937
                     /locus_tag="KB969_002092"
     CDS             3750..4937
                     /locus_tag="KB969_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBB6870059.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            4943..5299
                     /locus_tag="KB969_002093"
     CDS             4943..5299
                     /locus_tag="KB969_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBB6870060.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            5301..5639
                     /locus_tag="KB969_002094"
     CDS             5301..5639
                     /locus_tag="KB969_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBB6870061.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    5715..5971
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6034..7068
                     /locus_tag="KB969_002095"
     CDS             6034..7068
                     /locus_tag="KB969_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6870062.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            7061..7747
                     /locus_tag="KB969_002096"
     CDS             7061..7747
                     /locus_tag="KB969_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6870063.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            7771..8619
                     /locus_tag="KB969_002097"
     CDS             7771..8619
                     /locus_tag="KB969_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBB6870064.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            8816..9589
                     /gene="sufC"
                     /locus_tag="KB969_002098"
     CDS             8816..9589
                     /gene="sufC"
                     /locus_tag="KB969_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBB6870065.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            9602..10888
                     /gene="sufD"
                     /locus_tag="KB969_002099"
     CDS             9602..10888
                     /gene="sufD"
                     /locus_tag="KB969_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBB6870066.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            10885..12120
                     /locus_tag="KB969_002100"
     CDS             10885..12120
                     /locus_tag="KB969_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBB6870067.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            12107..12577
                     /locus_tag="KB969_002101"
     CDS             12107..12577
                     /locus_tag="KB969_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBB6870068.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            12582..13973
                     /gene="sufB"
                     /locus_tag="KB969_002102"
     CDS             12582..13973
                     /gene="sufB"
                     /locus_tag="KB969_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBB6870069.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14071..15213)
                     /locus_tag="KB969_002103"
     CDS             complement(14071..15213)
                     /locus_tag="KB969_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6870070.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(15264..>15786)
                     /locus_tag="KB969_002104"
     CDS             complement(15264..>15786)
                     /locus_tag="KB969_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6870071.1"
                     /translation="PEIPHKVFKDIQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDF
                     EIYLNEILANNINPLIEEYANQRHSISKELFFKRANSKLQDKIRNGDFKYGEKERMID
                     SLKQLLDEMDLAYKDISKYSSVEDFFYKITKNQFETEKFISDLSKKYNFPYEKNSIIA
                     KFLTDNHDKFKNN"
BASE COUNT         5146 a         2912 c         3331 g         4397 t
ORIGIN      
        1 ttgttgttgt tagaaggata tctgcaaaat taaaaacagt tgtgattcgg acattgttcc
       61 atgcgagaat cacaactgtt ttttcatgtt cattctaaac tttgatcagc caaataaata
      121 gtaaagccat cactgtttgg agaagcccga cagctaatcc ataagataag aagcgtgtac
      181 cttctttcat gaattttgca aagtctaaac gcagaccaat tgccgctaaa gcagtgatct
      241 caaaccagct gctgataaaa tgtgccgatt ggtcaataac tacaggtaaa gaaaacaagc
      301 tgttgaccaa acaaaagatc acaaacccta atacatacca aggaagcggt aattttcgtt
      361 ttttctgcgt atcagttggc gtttcaaaca gagctggttg tttcttgtgc atgaattttt
      421 caaacagata gacaacaaca acgagcatca taatacgtag aatcttaaat agcatggcga
      481 attcgacaac agaattgtca agtaagcttg ccccagcgac tacttgacca acagattgga
      541 gtgtaccacc caaaagtgca cttttttcaa tgagatttcc accaaacaac tgtaatccaa
      601 gaaaagggag agtcaacatc atcacagtac ccagtagatt gactagtgtg atgatctgtc
      661 ctttttcttc ctctttcgca tggatggaag gggcgattga agcaatagca gaagaaccac
      721 aaacagcgtt tcctccagcc atcatcaaag aagaagtatc gctgaattgc agttttttac
      781 caatcaagta agcaccgatg atagtgactg acatttgcag taacacaaaa acaattcctt
      841 ttacaccaat ttgagcaatc gtttgagctg tgacagttgc acctagtaaa aaaacagaga
      901 attctaatag tttgctttca gcaaattttg tgccgattgc tagaacaggc tgtttaaaaa
      961 aagtatttcc taataaaata cccaataaaa tagcaatagt cgctccacct aactgtggca
     1021 gataaatagc aagaagcctg ctgaaggcag cgatggcaaa agaaagcagt aaaccgggta
     1081 agatttcgcg gaccgctgaa tcctttacag attttattgg atgtgacaat gatttcattt
     1141 gatcggttcc tttcgtcaat aaatactaaa agcatactcg aacatagtag cactaaacca
     1201 gtattttgac aaaagaacaa gaggtcgtga caaaagtctt gtacgacctc ttgtttcgaa
     1261 taaacggtgt tccagaagta gcttctacgg aaataagccg aaatttcaca aaaatttgag
     1321 aagcaatttt cgtaaattcc ttcttatttc ttgaagctga ccacttcttt tacgacctct
     1381 tggtaaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccagt acaaaaacat
     1441 gaacagctgt ttttgtttgg ccgttcttat tacttgatgc agaacagctt tttcacaacc
     1501 tattgaatcg attattaagc gattttttta gaaacaaatt ttccatgttt gctatgttct
     1561 ttaattaaga aacgtacgta atgagcaaga acgtagaaga caactacact tgcaaacaga
     1621 cattccgcaa cttttaagaa atccaatacg ctactataga tacctaaact gttgaagtaa
     1681 tgaacagtag taaatatagc tgttgcagag ataacaagcg ggaatgtaaa ggctgcatag
     1741 cttggataaa aacgaagctt gaacaaacgt ggaagcatag acagcacaac gaaatacaat
     1801 acttgagata aagcgaacaa tgctacgaca agataaaaat taggttcagc aaagttttta
     1861 agataacctg ttaggcaaag agaaccaggt gctgcaacga tcgtaatcag cggacgtgtc
     1921 ggatgagcca tatttcttac gaaaaagaca cgtttgatga tgatcggcaa taagaacgca
     1981 tagcagatca atgaaatcca aaagaaaatt tttccaataa gtgggaagaa gttcccggca
     2041 gttacagtga tgaccccaaa tccaacgtaa atgataaacc agcttggata aattgcttca
     2101 attgaaagat cagctttgat aacatggtga taattgaaat aaaagacaag gatcacttgg
     2161 aagataacag cgcacagcca aatgaatttg acaattggtg caatactttc atatgaaaca
     2221 aaataagtac aaataaccat gagtgacatc gtaaaagttg gtgaaacgga ggcgatgatt
     2281 ggatcatgca acgtttgttt cgtgtgttcg aataagataa acaatttaac aaaaatgaat
     2341 atcataagaa tcatagagat accgccagtt agattgccta aagcaacatg gtgatagtct
     2401 ttaaacagat ttccaaggga agctaaccca aggatcaacc cgcagatcgg gatcggaata
     2461 attttcaaaa agttcttcat atataatatt ctccttttta tttaatagat tttagtacca
     2521 agatgaacga atacattgta aaatgaatag gaatgtatga ttacgagcaa gcagacagct
     2581 gattgtcttc atctaagtta ctagttggat cagcaactgt tttgttgtac atttctatta
     2641 tagatggttt tttgtatatt taaatcaaat agtttttata gtaattatca taaaaagtta
     2701 tggaagtggt gccatgttta agttattaac gacttttcga gcagtatatg aaacaagaaa
     2761 tttttccaga gcagcagaag tactgttttt atctcaacca gcagtctcga atcaaatcaa
     2821 acagttggag cgggaattga atatcgatct ttttcaacgt aacggaagaa aagagatgct
     2881 tccaactaag caagccgact tattatatga acggacactg gttttgttag aagaatggga
     2941 agaaactcag caaaaattgc tcaatgaaca aaatgaagaa gaagtatgtc ggatcgttgc
     3001 ttcccacacc tttgctgtct atcttttgcc tcagttgatg aaacatctga tcaaaaggtt
     3061 tcctaaagtg cattttgaga tcgaaatcac gaattctcat gaatcattag aacaagtagc
     3121 gaaacatgaa tccgattttg gttttatcga aaagccatta gagacttccg gcgtacaaag
     3181 atactctttg atggaagacc agctagtcat cgctggggac ccaaaaagca aattgtggct
     3241 tgtaagagaa gcaaactctg gtgtttttca ttacacgcag cgttattttg aagagatgaa
     3301 tatccaagat aagaagatga tcgtgaaaag taacgatgta attgttgcgt tgctgaagga
     3361 aggaatcggt cgctcgattt tgtctaagcg ctctgttcca gaaaatgtgc caatgactcc
     3421 gttgaatttc catcgatatt tttatttcat ccaacgaacc aatctggttt ctgatcagct
     3481 gctagagatt gccgaagaga tccttcgata caatgaaagc acagaaactt ctcacagcga
     3541 ggagaatctc agctggtaga taattgcatg tatcaaaaaa agttctatga tacactaaag
     3601 ataagcagta ggcttttgta ctgcatttgc tcaagcaact gcacaaacgg aaagttaatt
     3661 tttcccaaat gtctatggaa agactttcca ttatctaact ggaccgctat aataatcagc
     3721 agtatggttt ttaagaaaag ggatgaaaca tggaaaaaaa attaaaagct tcgaacgata
     3781 atcgtattga ttatggcgtg attttaccag tctttctgtt atgtttgatt ggtctgctct
     3841 cattatatgt agcacttagc catgatccga acaatccagc agtcttgaaa ggcgtaggga
     3901 tgcaagttgt ctggtattta gttggagcgg cagcaatcgt tgtcatcatg catttgaatt
     3961 ccaaatggat ctggaaactg actccttacc tttatggttt ggggttagtg gtaatgggac
     4021 tcttgctcaa attctatgat cagaatttag ctgcttcaac agggtctaaa aactggtttc
     4081 gattcggtgc gtttactttc cagccagcag agttgatgaa gattgcgtac atcttgatga
     4141 tggcactgat cgtaactaaa cataatacgc aagtaaaaga acggacgatg aaatcggact
     4201 tttggctgat tgggaagctc ttgatcgtga caataccggt tttagcattg atcatggccc
     4261 aagatgactt tggaacgatg cttgtctttc ttgcgatctt tggcgggatt ttcctgatgt
     4321 ctggaatctc ttggcgcatc atcgcacctg tagtaatctt ggcagtagtc gttggagcag
     4381 gaacgatctt cttggttacg actgaaggcg gaagagactt gctttataaa gttggattca
     4441 aatcttatca gtttgcacgt attgattcat ggctggaccc tttccatgat acgtcaggaa
     4501 tgagttatca gccggcccaa ggacttttgg caattggtac cggtggcttg tttggtaaag
     4561 gattcaacgt aagcaatatc tatgtgcctg ttcgtgagtc cgatatgatt tttaccgtta
     4621 tcggtgaaaa cttcggcttt atcggtggtg cattcgtcat tttcttgtat tttattttaa
     4681 tctatcgtat gattcgggtg tgtttcgata cgaataatga attttacgcc tatatcgcaa
     4741 gcggtttgat catgatgctg ctgttccatg tctttgagaa tattggagca aatatcggat
     4801 tacttccttt aacagggatc ccattgcctt tcattagtca gggaggatcc tcgattttag
     4861 ggaacatgat cggtatcggg ttgatattat cgatgagata ccaaaatgaa gcacctgcaa
     4921 gatcttcaag gaggtaagaa aattgtacac cttttactgg tacccgaaat gttcaacatg
     4981 caaaaaagcc aaagcgtggt tagaccagca tggcgttagt tatcaaaccg ttgatatgat
     5041 caaagaagta ccgaaggcct caacgattga gacttggcta gaaacgagtc aagtaccaat
     5101 ccgtcgcctg ttcaacacaa gcgggatgaa atatcgggaa cttggactga aagatcaagt
     5161 aggcgagttt acggcttcaa aagcgagcca agtcttatcg acagatggta tgctgatcaa
     5221 gcgaccactg atcttacgag aggaccagct tgttgcaatt ggattcaatg aaaaaattta
     5281 tgaaggagaa ctgatataaa atggcaggca agcatttgaa gaaaaaggac aacctttgga
     5341 tcttatttaa tggaaaagaa tactgtgttg gtttgacaaa tgaagcgcaa gaagaacttg
     5401 gagacatcac gtttgccaat ctgccaaaag caggacaatc gctaaaaaaa gatgaacctc
     5461 tgatcgaagt tgaagcggaa aaagcggtca atgaatttgc cagcccgcta acgggtacag
     5521 tttcttctgt taatgataaa atcggtgaag atatcaatat cttgaatgat tcagatgaaa
     5581 tgaatgcgtg gatcttaagt ttcaaagatg ttgatccaaa agaatttgac gaattataaa
     5641 atcagaaaat cacttgaaaa aagttgacac tgattcttcc agttgctata atcataagca
     5701 atcctatatg aaacgagaaa gctttgaaaa gaagagtaca tgtcacggac gtttgaagag
     5761 agccctgttt gctgaaaatg ggtaacgaaa atgagatgga agatggtctt agagcagagt
     5821 aagcgagcgt aagcaaactt actacgggag tgcccgttac agcgcgacag tatacggaaa
     5881 gaagctaagt ccaagtactg gaagaggctg ttattgcgaa gtaacggtaa atcaaggtgg
     5941 taacacggaa gttcaagctt tcgtcctttt gcttaaggca agagggcgaa ggcttttttg
     6001 tttgaaaaat tataagagaa agatgtgaat ggcatgtcat taatccaact aacgaatgtc
     6061 aaaaagacat tcaatgggaa aaacggaaac atccaagccg tcaatgacgt ttcactaaac
     6121 gttgaaaaag gggatattta tggaatcgtc ggctattctg gcgcaggaaa aagtacatta
     6181 gtccgtctcc tgaatggact tgagcttccc acgagcggcg aagtgatcgt aaacgatcaa
     6241 gatattacaa aattaaaaaa caaagaatta cgtacattcc gaaagaaaat cggtatgatc
     6301 ttccagcatt tcaacctgtt atggtcaaga actgtacttg aaaatatcca gctgccgctg
     6361 gaattagctg gcgtaccaaa gagcaaacgt aaagaacggg cagaagaact gttgcgttta
     6421 gtcgggttag aaggacgcgg acaagcatat ccttcacaac tttccggcgg acagaaacaa
     6481 cgcgtcggta tcgcacgagc attggcaaat gatcctgaga tcctgctttg tgatgaggct
     6541 actagcgcat tggacccgca aacaacagaa gaagtattag acttattgtt agcgatcaat
     6601 aagaaattga atttgaccat cgtcttgatc acacatgaaa tgaatgtgat ccgcaaaatc
     6661 tgcaacaaag tcgctgtgat ggagttgggg aaagtcgtag aagaaggaga cgtattgact
     6721 gtcttcagac aaccgaaaaa agaagtaacc aaacgctttg tacaacaaga catcgaacca
     6781 gaagctgatt cgacagaact attagctgaa ctcatcaaag aaaatccaag cggccgtttg
     6841 gcaactttga cctttagcga aagaaatgcc aacgagccag tcatttccca agcgattcga
     6901 cgctataaca tcgatgtcaa cgttgtgtat ggaaagatca aacaagtgaa agaaggttcc
     6961 tttggttcat tgactgtctt gatgactggt gaaaccaaag aattagatca agcagaagtg
     7021 ttcatcaaag aacaaggagt aggaattgag gtgatccatc gtggataaaa gcttttcaga
     7081 aacatatcta gattttaaac aaatcaaccc ggaaacgatg aatcaggcta tccttgatac
     7141 actatatatg acattaatct caatggtctt agtgacgatc atcggattag ttttgggatt
     7201 gatcctttac tctattggac gcaaaaacaa accgtatgct cgaatcattt atggaatcgt
     7261 atcgatcatc agtaatattt tccggtcaac gccatttatg atcctgatgg ttttgatcat
     7321 tccatttact aaagcaatcg taggcactat gctaggtgcg caagcagcca ttccagctct
     7381 tgttttatcc gcagcaccat tttatgcccg tctagtagag attgcttttc gtgaagtcag
     7441 ccctggtgta ctggaagcag cagatgcaat gggagcaagt tactgggaaa tcatctggaa
     7501 ggtcttgata cctgaaagta ttcccgcatt gatttctgga ttaacagtta caacgatctc
     7561 gatgatcgga tttactgcga tggccggcgc gatcggcgca ggtggacttg gaggtcttgc
     7621 ttggcaggaa ggctaccagc gtggtaatct aacagtgaca ttcgttgcga ctttaattat
     7681 tttactaatc gtatttatcg ttcaaggaat cggtgatttc ttaactaaga aaacagacaa
     7741 aagataatag gatatagggg gatgtaggat atgaaaaaga aaatttttgg atttgcagca
     7801 gcgcttttgc tgactgtagg attagcagca tgcggtaaca acagcgacag caaagattca
     7861 gcaaataaag cagacgacac gacattgaaa gtcggcgctt caccgacacc gcacgcagag
     7921 attttggaac atgtgaaacc attattgaaa gatgaaggaa tcgatcttga aatcgtcaaa
     7981 ttcgatgact atgtattacc gaaccaatct ttggaagaag gcgacattga tgccaattac
     8041 ttccagcata ttccttattt gaacaaagaa atcaaagaaa aaggatatga ctttgtcaat
     8101 gccggtgctg tccacatcga accaatgggc ttgtactcta aaaaagtcaa agatgtttcc
     8161 gaattaaaag atggtgcaac aatcattact tcaaattctg aatcagactg gggacgcatc
     8221 atcacaattc tacaagatgc tggcttagtc aaagtcaaag atggagtaga tctggaaaca
     8281 gcaacattcg atgatattga agaaaaccct aagaacttga agttcaacca tacgatcgac
     8341 ccatcacttt tagcttctac gtaccaaaat gatgaaggtg acctagttgc aatcaacgca
     8401 aacttcgctt acggcgcagg gttgaatcca ttagaagatg ccgtattgct tgaaaaggac
     8461 aactctcctt acgtgaatat tattgcgact cgtaaaggtg atgaagacag tgacaaaatc
     8521 aaaaaactga ttgaagtgct tcaccgcaaa gaagtccaag aatggatcac agacaaatgg
     8581 ggcggctctg ttaaaccagt aaaggctgat gcaaaataag gtatggaaca aaaaagatga
     8641 gaaataagtc tgtaatggct tatttctcat cttttttata cctattctaa tttagaaatc
     8701 aaaattgttt aataataaat aaaagatatt tgattttagt aaggaaggtc attgcgcttc
     8761 attctcaatt agtctaaaat gagtgagaac gaaagagaat ttgggggtat aatgcatgtc
     8821 tgtcttagaa ataaaaaatc tacatgtgtc gatcgaggaa aaagaaatcc ttaaaggcgt
     8881 aaacctaaca atgaaaaccg gagaaatcca tgccatcatg ggacctaacg gcacaggaaa
     8941 atctacctta tctgccgcta tcatgggcaa tccaaactat gaagtaacag aaggcgaaat
     9001 tttgtttgac gggaaaaatg ttttagactt ggaagtagat gaacgtgcgc gacttggctt
     9061 atttttagct atgcaatatc caagtgagat accaggtatc acgaatgcgg aattcatgcg
     9121 tgcagcgatc aatgcgaaac gtgatgaaaa cgacaaaatt tctgttatgg catttttgaa
     9181 aaagttagat gaaaaaatgg ctttactaaa tatgccagaa gaaatggctg aacgttatct
     9241 gaacgaaggt ttttctggcg gagaaaagaa acggaatgag atcctgcaat tgttgatgtt
     9301 agaacctaca tttgcaattt tagacgaaat cgattcaggt ctggatatcg atgctttgaa
     9361 agtcgttgct aaaggagtaa atgaaatgcg cggagacaat ttcggtgcat tgatcatcac
     9421 ccactatcaa cgattattga actatatcac acctgatgtc gttcacatca tgatggaagg
     9481 ccgagtagtc atgacaggga atgctgacct agctaaacgt ctggaagcag aaggctacgc
     9541 tggtatcagt aaagaattag gaatcgacta taaagaagaa gaagcgtaag ggggagcaag
     9601 aatgaaagaa aaaaactggc tcgattatct tgacgcggta aatgattttt ctttaagtaa
     9661 aggcgaacct gattggatga gaaccttccg tcaagacgca ctagcgaaag cagatgaact
     9721 gccattgccg catatcgatc gggtgaaatt ccatcgctgg tcgttatttg atgtgaaaga
     9781 aacacaaacc atcagtgaaa caggcacgat tccggcattt gatgcaatga aagacaatcc
     9841 tgtgcttgtc caacaaggtt catggacgat ttttgaacaa ctgcctgtgg aattagcaga
     9901 aaaaggagtc atttttaccg acttgttcac tgcaatgatc gaatatccag aactagtcca
     9961 agaatattat atgaaaaaag cagtaaacat gaacgaagac caattgactg cactccatgt
    10021 agcttttatg aacagcggta ttttcctgta tgtgcctaaa aatgtcgtga tcgatgaacc
    10081 actcgagtcc ttattcattc aagatggcgc atccgatgag cacttcttca agcatgtgtt
    10141 gatcgtggca gatgaacata gtgaattttc ttatctggaa cgtttccaga caaccaaaga
    10201 acaagtagca aaatcatcag gtaatatcat cgtggaagtc atcgctaaag ctggttcaaa
    10261 aatcaaatat tcagccgtag atcaattagg agaaaatatt acttcttata tgaatcgccg
    10321 tgggcacatt ttacgagatg cttctgtcga ctgggcaatt ggtgtcatga atgacggtca
    10381 tgtgatcgct gactttgact cagatttagc aggagaaggt gcacacgcag aagtcaaaat
    10441 cgtggcaatc agctcgggca gacaaatcca aggaatcgat acacgagtaa ccaataaagc
    10501 ccctcatacg atcgggcata ttttgcaaca cggagtgatc cgagaaaaag gaacattgac
    10561 ctttaatggt atcggccaca tcttgaaagg ggcaaaaggt gcagatgccc aacaagaaag
    10621 tcgtgtcttg atgctttctg ataaagcacg tggtgatgcg aatcctattc ttttgatcga
    10681 tgaaaacgaa gtaactgctg gacatgctgc cagtgtagga cgagttgatc cagaagaaat
    10741 gtactatctg atgagtagag gattgcataa agaagaagca gagcgcttag tgattcgagg
    10801 attcctcggt tctgtcttaa cagcaatccc tgtagaacaa gttcggaaag aattagtcga
    10861 agtaatcgaa gggaagttga atggatgatc gatgctaaaa agctacgcaa tgattttcct
    10921 atcttatttc aagacgtcaa tgatgaacct ttagtttatc tggataatgc agcgacgacc
    10981 caaaagccaa aacaagtact ccaggcatta gcgtactatt acgaacacga taacgccaat
    11041 gttcatcgcg gtgtccatac gttagcagaa cgcgcgaccc atgattatga acaagcaaga
    11101 gaaaaagtac gggcgttcat ccatgcaaaa gaaacagcag aagtgctgtt tactcgtggt
    11161 acgacgacaa gcttgaattg ggtagccaga accttcggcg accgctatat caaagcagga
    11221 gacgagatag tgctctctta catggaacat cattctaatg ttatcccgtg gcagcagttg
    11281 gcaaaacgaa caggtgctgt cttgaaatat atcgaactaa cagaagaagg cttcctggat
    11341 atggaggatg cagcgaaaaa gattacggac aaaaccaaaa tcgtctccat tgctcatgta
    11401 tccaatgtct taggtgtctt caatcctgtt caagaattag ctgaacttgt ccatgaaaac
    11461 ggcggggtca tcgtagtaga tggtgctcaa tctgccccgc acatggccat tgatgtccaa
    11521 gcactagact gtgatttctt tgctttcagc ggacacaaaa tgtgcggacc aacaggtatt
    11581 ggtgttttat atggtaaacg aaaatggtta gaagaaatgg aacctgttga atttggtggc
    11641 gaaatgatcg attttgtcga attatacgac agtacatgga aagaactacc ttggaaattc
    11701 gaagcaggga caccaaatat cgccggcgct atcgcattag gccatgcaat cgattatttg
    11761 caaaaactcg gtatggacaa tatccatcga tatgaagaag aactagccgc ttatgtgttg
    11821 ccaaaattac aagcaattga tggattgact gtttatggtc cacaagaccc gaattttcgg
    11881 acaggagtcg ttgcattcaa tttggatggg ttacatcccc atgatgtcgc gacagcttta
    11941 gacatggaag gggtagccgt cagagcaggt catcattgtg cgcaaccgct attgaagtac
    12001 cttgaagtat cagcgactgc tcgcgcgagc ttttatttct acaacacaac gcaagacgcc
    12061 gaccgtttag ttgaagcaat catggcaaca aaggagtttt tccaacatgg gactatctaa
    12121 attagacaat ttataccgtc aagtgatctt ggatcattct tcccatccgc atcatcgtgg
    12181 aagcttgact gactcgacaa gcaagatcga attgaacaac cccacatgtg gagatgtgat
    12241 cgaattgcaa gtcgatgtaa aagacggaat catcaaaaat atcgcctttg acggcagtgg
    12301 ctgctccatc agtacggcaa gtgcctcgat gatgacagac gccgtcatcg gaaaatcaat
    12361 agaagaagca gaacatttaa ctgtagactt tctacagctt gtccaaggaa aagaagtcaa
    12421 agatcccgac caattaggcg atgctgctat gcttggtggt gtagctaaat ttcccgctcg
    12481 gatcaaatgt gcgacacttg cctggaaagc actaggaaaa gcaatggaaa acgatggtac
    12541 cgcagctttc catcattacc acaaggaaga ggagtgagaa catgggcgta ccagaattag
    12601 aagaatataa attcgggttt cacgatgatg tcgaaccggt tttcagtaca ggagaaggct
    12661 tgacagaaga agtgatccgt gagatgtcaa gaatcaaagg cgaaccagaa tggatgcttg
    12721 aattccgtct gaaatctcta gaaacattta acaaaatgcc aatgcaaaca tggggccccg
    12781 acctttcaga catcgatttc gatgccatca aatattacca aaaaccaagt gacaaacccg
    12841 ctcgtgactg ggaagacgta ccagaaaaaa tcaaagatac atttgaaaag attggtatac
    12901 cagaagctga acgagcttat ctagccggtg cttccgcaca atatgaatca gaagtcgtgt
    12961 accataatat gaaagatgaa ttcgaaaagt taggaatcgt ctttactgac actgactctg
    13021 ctttgaaaga ataccctgaa ttattcaaag agtacttttc aaaacttgta ccgccaaccg
    13081 acaacaaatt agcagcgctg aattcagccg tatggtcagg tgggaccttt atttacgtgc
    13141 caaaaggcgt caaagtcgat gttccattac aaacgtactt ccggatcaat gcggaaaaca
    13201 cggggcaatt cgaacgtacg ctgatcattg ttgacgaagg agcaagcatc cactatgtcg
    13261 aaggttgtac ggcacctact tattcaagta acagcctgca tgccgccatc gtagaaatct
    13321 ttacaagaaa agatgcgtat tgccgttaca caacgatcca aaactggtca gacaatgtgt
    13381 acaacttagt aaccaaacga gcaaaagcat acgaaggcgc aaccgttgaa tggatcgacg
    13441 gaaacctagg tgcaaaaaca acgatgaaat acccaagtgt ttacttagat ggaaaaggtg
    13501 cacgaggcac catgctctcc atcgcctttg caggagcaaa ccaaatccaa gatacgggtg
    13561 caaaaatgat ccacaatgca ccaaatacat ctagctctat cgtctctaaa tcaatttcaa
    13621 aagacggcgg agaagtaaac tatcgaggac aagtaacctt tgccaaaaac agtgcgggtt
    13681 cgatctctca tatcgaatgt gacacgatca tcatggacga atggtcgaaa tccgatacga
    13741 tcccattcaa tgagatccac aacagccaag tctctttaga acacgaagcc aaagtctcaa
    13801 aaatctcaga agaacaactc tactatctga tgagccgagg cctgaccgaa tctgaagcaa
    13861 ctgaaatgat cgtcatgggc tttgttgaac cattcaccaa agaacttcca atggaatatg
    13921 cagtcgaact caatcgattg atcagttatg agatggaagg gtctgtaggt taataactat
    13981 ttcattgctc gaaacgttga tattaaagcg tttcgagcgt ttttttattt gtattttaat
    14041 ggttggctac gtttttggct acgtttggaa ttattcgccc ataaattttg caaatcggtc
    14101 accagttttc ttaacagatt gtggtgtgac atgagcatag atattcatgg tagttttaat
    14161 atctttatga cctaatcgtt cctgtacttc ttttatcgac gcaccacttt caaacaataa
    14221 gctacagtgg gtatgcctaa atccatgtgg agtaatttga ggctccatcg gtgtcttttt
    14281 gtaaatccag tctaaccaat cgtttactac ttgggggtag tacaacttgt ttgtgtttgt
    14341 agtgaaaaga aactgttttg gtgaattcgt gttatagcca tataagatca ttattttcat
    14401 ttgttcttgt tgccaaatac gcagttgttt aagtgtaaaa tcatcaagct gaatcgttct
    14461 tgatgaattt ttagttttag gtacttgtag aactacttga ttaaactcgt cttgagcgat
    14521 agttttacca attgttattg ttttattgaa atagtctata tcttcccatt gaagcgccaa
    14581 tgcttcgctt ttacgcattc ctgtataagc taataaacgg aaaaaagtgt acagtttaac
    14641 tgaattattt tctttagtat tctgtaaaaa cagttgtaat tgatctttcg tgtaaaactt
    14701 caagggttgt tcttcttcaa tttttcttgg aagcaatgtt ttagacatag gattatcctt
    14761 acagacttcc attgctactc caaatttaaa tatttgagca gttgtttttc tcaagaaacc
    14821 atattgtttt aatgttttgt gccattcatt cacctgtttt tggcaatagc taacacttat
    14881 tttatccaat cgtaattccc caaaagcagg taatatatgg tttttgcaaa aacgttgagc
    14941 aacggcaaca gaagacggtt ttactcttgt tctgtagtta tcaatccata attcatacaa
    15001 ctcttgaaaa gttgtaacat tgattttaaa ctcttgtttt tctttaaagt ctacaagtag
    15061 tctattaagt gctgtttgcg cctcagcttt tgatttgaat cttctacgct ttgtacgtat
    15121 atcttttcca gtcttgggat ctttccctaa ataagtttca aatccccaat atttttcgcc
    15181 attttgtaat ttataactaa aaaatgttgc catttgattc tctccttact tcattattgc
    15241 aggtagagaa gttatttgaa gaatcaatta tttttaaatt tatcgtgatt atcagttaaa
    15301 aattttgcga ttatactatt tttctcatat gggaaattgt attttttact aagatctgaa
    15361 ataaattttt ctgtttcaaa ttggttttta gtaattttat aaaagaaatc ctcgacagat
    15421 gaatactttg aaatatcttt ataggctaag tccatttcgt ctaatagctg ttttaaagaa
    15481 tcaatcattc tttctttttc accgtatttg aaatcaccat ttcttatctt gtcttgaagt
    15541 ttactgttgg ctcttttgaa aaatagctct ttagagatag agtgtctttg gttagcgtac
    15601 tcttcaatca gaggattgat attattagca agtatctcat ttagataaat ttcaaaatct
    15661 tttgagtaat attttgtaaa tatatttttt attataggat tcaataactc atagtcttta
    15721 tctagcgaaa acgtatcact atatctttct tgaatgtctt taaagacttt gtgaggtatt
    15781 tctggg
//
LOCUS       DADVXV010000070        15748 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.071, whole genome shotgun sequence.
ACCESSION   DADVXV010000070 DADVXV010000000
VERSION     DADVXV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.071"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            693..788
                     /locus_tag="KB969_002105"
     CDS             693..788
                     /locus_tag="KB969_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6870072.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1090..1335)
                     /locus_tag="KB969_002106"
     CDS             complement(1090..1335)
                     /locus_tag="KB969_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870073.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
     gene            1680..1964
                     /locus_tag="KB969_002107"
     CDS             1680..1964
                     /locus_tag="KB969_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870074.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            1967..2383
                     /locus_tag="KB969_002108"
     CDS             1967..2383
                     /locus_tag="KB969_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870075.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            2754..3434
                     /locus_tag="KB969_002109"
     CDS             2754..3434
                     /locus_tag="KB969_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBB6870076.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSIASAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASPTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPD"
     gene            complement(4049..5089)
                     /locus_tag="KB969_002110"
     CDS             complement(4049..5089)
                     /locus_tag="KB969_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6870077.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(5438..5764)
                     /locus_tag="KB969_002111"
     CDS             complement(5438..5764)
                     /locus_tag="KB969_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870078.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(5751..6554)
                     /locus_tag="KB969_002112"
     CDS             complement(5751..6554)
                     /locus_tag="KB969_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6870079.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(6907..7197)
                     /locus_tag="KB969_002113"
     CDS             complement(6907..7197)
                     /locus_tag="KB969_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6870080.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(7333..7512)
                     /locus_tag="KB969_002114"
     CDS             complement(7333..7512)
                     /locus_tag="KB969_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870081.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(7509..7859)
                     /locus_tag="KB969_002115"
     CDS             complement(7509..7859)
                     /locus_tag="KB969_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870082.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(7852..9177)
                     /locus_tag="KB969_002116"
     CDS             complement(7852..9177)
                     /locus_tag="KB969_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6870083.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            9627..10241
                     /locus_tag="KB969_002117"
     CDS             9627..10241
                     /locus_tag="KB969_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6870084.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(10406..10648)
                     /locus_tag="KB969_002118"
                     /pseudo
     CDS             complement(10406..10648)
                     /locus_tag="KB969_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10852..12171)
                     /locus_tag="KB969_002119"
     CDS             complement(10852..12171)
                     /locus_tag="KB969_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HBB6870085.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(12326..12913)
                     /locus_tag="KB969_002120"
                     /pseudo
     CDS             complement(12326..12913)
                     /locus_tag="KB969_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13551..13808)
                     /locus_tag="KB969_002121"
     CDS             complement(13551..13808)
                     /locus_tag="KB969_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6870086.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(13801..14070)
                     /locus_tag="KB969_002122"
     CDS             complement(13801..14070)
                     /locus_tag="KB969_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6870087.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(14201..14380)
                     /locus_tag="KB969_002123"
     CDS             complement(14201..14380)
                     /locus_tag="KB969_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870088.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(14761..15327)
                     /locus_tag="KB969_002124"
                     /pseudo
     CDS             complement(14761..15327)
                     /locus_tag="KB969_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15403..>15748
                     /locus_tag="KB969_002125"
     CDS             15403..>15748
                     /locus_tag="KB969_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HBB6870089.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYA"
BASE COUNT         4925 a         2856 c         2466 g         5501 t
ORIGIN      
        1 ttccgttttt tcatccattc ctttcttccc cccttacaaa taaataataa cctttaacaa
       61 ccaactcgta aataggttgg ttgttattat acaaaaggat attagtactc agataaaaag
      121 ttgttagtac tcagataaaa agttgttagt actcagataa aaagttgtta gtactcagat
      181 aaaaagttgt tagtactcag ataaaaagtt gttagtaccc ttctgtatcc gttgggagag
      241 taaggctcaa ctgcccccta aaaagggttc taaaaaatct ttaaaaaata aataaaataa
      301 acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc cactttttaa aataaacagg
      361 ttcgcgcatg atattaaact gccaatctag ctccctatgg tcgctgtaag aaggagtgat
      421 cgctacgctc tcacatttta cttgcagcag tcgcctttag gctccttcgc caaaaataat
      481 tcattaggga ctcctttgtg gcgtcctgag agctcgtcta agccgttcta agacaagatt
      541 cgataaaaac tatgtccttc gttctaaagc gccttacagg cggtcagggc aagccctaac
      601 aaccccaagg caataaaaaa cttaggctta tttttgcttt tttattgtat aattgattgt
      661 cgcctatccg acagtcttgc gactggaagg aggtgtgttt cgtgttcact aactttattt
      721 gctcccttct tgttgggctt ttaagcgctt tgttcagtta ctggttgaat aaccgaaaca
      781 agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa agccccagag aatccgacct
      841 ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa tcaaattata acagaaataa
      901 atatttattt caaaaatatc ctacaaaagt ctaaaatccg taattatttc ttatatgcaa
      961 catttacaaa taaagtcgct ctgagagctc gtatttttcg atttaagacg ttttatttag
     1021 tttttggtgt atttcattgg tccaagctaa aaaactctta gaagcgattt tagagccatt
     1081 taaacccact taattatatt ctccatgaaa ttcgctccat gcgtcaaaag ctgcgtctga
     1141 aattccgccg tcttcgttca ctagttgcat taatttttcc aacgatcgtt ttctttcggg
     1201 tgtcatattt ttatattcca acaatttttc gtctgttaaa tcgaacttga ttgcttgaat
     1261 tgcttgctct aatttttcta agttttgaaa atattcgtaa ggaaattttt ccattttttc
     1321 tttctccagt ctcacaattt ttctagaaat aaaatcactt ctttgccgtc tatactctca
     1381 aaaaaaatgt cgtttgaaaa actaaataaa tttttgatcg tgcattttta aatttggtta
     1441 tcgattacac gtgcagcact cccccccgaa ttttaaagag cataaggaaa cgtgtaccca
     1501 ctttctaaaa aaagtgggta gataggctgt gcctatcacg tttctcagaa aaaaatttga
     1561 tatcactttt tcgccatcgt gggtagctta tgtatagcat tttggcaaaa aacagctata
     1621 caaatatagt atttgtatgg tatacataaa ttatacataa ttgcaaaagg agatttttta
     1681 tggacatttt agttcggaat attgatccaa agtttgttgc aacaatagac aaacgttgcc
     1741 aagaactcac gaataaaaca ggagaaaaat ggagtcgaaa taaatatcta aaagttttaa
     1801 tcgaaagtga ttttgaccgt caacttacga cttacaaaaa agaccaattc gatttattgc
     1861 tcgataaatt tattgctatc caaacagaaa atactcaaat attaagcgag tatgtctaca
     1921 caaataatca aatcattgaa atgcttatcg gaggaatgat ataaccatga gaaaaacttc
     1981 tgtccaaaaa catgttactt tgtaccctag tcatgttgac gttttagatt ccatcatcga
     2041 aaaaaatcca gatatcaata actactcgga agccattcgc tttttatgta tgagttatga
     2101 acccgatacc aacacgacca ctaccagcaa tcaggcaaaa ctaaatgcta tgggaaaaga
     2161 aatttccatc atgactgaaa tcatcgcaga atttgctgat ttatatctaa aagatacagg
     2221 cgttcttatt ggcacaaatt ctaaagtata tcaagaagtg aaagaaaaaa tcgaagctaa
     2281 actaaatcca tcaaatcgaa atcgaccaaa gaatcatcaa aaagaaacca gtcaaacagt
     2341 cacttctaga aatttcgacc caacaaattt tctaaaacga taaaaaacag ataggagtta
     2401 ttcctatctg ttttttattt agaagcccca tacaatatgc tagaatgtac tagcaatctt
     2461 agtcggttgt aagggacttg tctacttgct taatgtaagg ggggcgagtt cttttttatt
     2521 tattcttcta accagttacg cagagaaatc tttggcaaat ctgacgttag gcttgaaaaa
     2581 gtaaattcta atttggcgat tttattgccc ttttttgctt ttatttttgt gactttaaga
     2641 tcattgaagt atttttttag ttctcgtaat gcaggatttg gttctgttgc aaagttttaa
     2701 atctactatc aaataaggta gaataataga aaaagatagc aggaggaatg acgatgaatc
     2761 attttaaagg aaagcaattt cagcaggatg tgattattgt agccgtgggc tactatcttc
     2821 gttataacct tagctatcgt gaagttcaag aaatcttata tgatcgtggc attaacgttt
     2881 ctcatacgac gatttatcgt tgggtgcaag aatatggcaa actactctat caaatttgga
     2941 aaaagaaaaa taaaaaatcc ttttattcct ggaaaatgga tgaaacgtac atcaaaatta
     3001 aaggaaaatg gcattatttg tatcgagcca tcgatgcaga tggtttaacc ttggatattt
     3061 ggttacgtaa aaaacgggac acacaagcag cctatgcttt tcttaagcgg ttagtgaagc
     3121 agtttgatga accgaaggtt gtagtcacag ataaagcacc atcaattgct agtgccttta
     3181 agaaactaaa agaatacgga ttttatcaag ggacagaaca tcgtaccatt aaatacctga
     3241 ataatttgat tgaacaagac catcgtccag taaagagacg caataaattc tatcgaagtt
     3301 tacgcactgc ctcacccacg attaaaggca tggaagccat ccgaggatta tataagaaaa
     3361 cccgaaaaga aggcactctc ttcgggtttt cggtctgtac tgaaatcaag gtattattgg
     3421 gaatcccaga ttaaatcata gataccgtaa gggattttat tctttattta aaactttgca
     3481 acagaaccgt ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc
     3541 ttaatgcttt cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc
     3601 tttctttttt tgtattttca attatcacaa tttatcgtcc aaaagtgcag aacgaaaatc
     3661 aattcatcac aagcatatca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt
     3721 gtaattgaat attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg
     3781 aaataagtga attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac
     3841 actagttccc tatttttttg aatgaaaaat aactaaaata tctaacgatt atgactttaa
     3901 aacctacgtt tgcgattgtt ttcataaact tttaatctaa aaactccgga ataatagcta
     3961 tttatttgta acatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat
     4021 catttttata gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg
     4081 gtaattcgtt aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga
     4141 caaaccaatt ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt
     4201 tttgtttttg ataagctttc agcaaagtca tatataatcc tttgtcagca tcaattccat
     4261 aagattccag ttcttcataa acaacaactg tttgctctaa ttcttcagct tttttctttg
     4321 cattatgaat agtttggacg gttttttgag cgtcttcgta agtactagaa aatgttttta
     4381 tcaagtttaa tacattttct ggtacaaatg tatttatact gtcctctttc atgatgtcga
     4441 cgaagttatc tagtaaaact tgattttgta actgatcagt ttcagtgtct attatgtgtc
     4501 tattagtgtc tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg
     4561 agtccttgat atgactggat tttgccgtat ttgcgatttt cgcaattacg gtggtatcat
     4621 tgatttctcg cggttttgcc gtatttgcga ttttcgcaat tacggtggta tcagtattgt
     4681 cttcctcttc catgatttta aagacgtctt gattcgttac ttctggcttg cctaagtaca
     4741 ataaattagg catggattca atcttaccgt cacgtttatt tactcttcct ctcttctgtt
     4801 tcagaagacc tgctttttct aattcctttt tgattttaga tactttacct tcgcggcatt
     4861 gtaacaattt cattaattct tcaactgtga atatgaaaaa tatattatca tcagaatcta
     4921 cccagttatt tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg
     4981 catcatttga tagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat
     5041 atttttcacg ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc
     5101 tttctgtagg atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta
     5161 tccactatat atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt
     5221 ttttatcttt ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaagg
     5281 tttaagctca tagtaactat atcacgatat tacaataata ttatatcacg atatcgtaat
     5341 attacaatat gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa
     5401 tatcacgata ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg
     5461 ctagtttata tccttcaatc aagtattctt caggtatgga ctttaatagc gcatcttcta
     5521 taacgtctgg tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca
     5581 ttagaattgg atttatacga atgctatctg ctgttcttac actacttcct tgatctttta
     5641 tgactttact tatatttttc ttggttaatt cgatttcttc tacttctttt gatttaaaat
     5701 tctttttatt tttatttcct agtaatctac ttactgcagc ttgactgcga ttatcttctg
     5761 ccatcaaaat caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca
     5821 gctgttgagg gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg
     5881 gttattgtcc tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg
     5941 gttgctgcag acgtcatttc tttagaaatg ttataacgct tattatactt agtaaataga
     6001 actcctcgta cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt
     6061 aactttatta gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca
     6121 gaaacagtaa atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata
     6181 taatcatagt tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact
     6241 tgagtaaatt ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct
     6301 ttatagtcca gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta
     6361 ggttggtttg ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca
     6421 atgtccacta aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg
     6481 ctagtcgtag ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt
     6541 aaaatatccc ccattcatct tatattataa tataattata tcataatatt gtgatattgc
     6601 aatatcgtat atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat
     6661 cggttcggat ataaagatta ttcatatgtt attcgaaatt aaaataatca ctttttatta
     6721 ctttaaaatt ttttattaat gataagaaat atgttttgcg agcagcaact agaataattt
     6781 aaacattact aaactgtcta tattgttact aataattccc ttcttatagt gcattttctt
     6841 agaaaaaaac aatattacga tatcatgata ttaagatatc gtaatattat acaattgtga
     6901 ttgatattat atatgttttt ttattttttt atcatgttta atcttgaagg aatcatattc
     6961 tttttctaaa gacaggagct tttcataaac atcagacatg tttaaactag aggccaggct
     7021 taaatcataa acgaatgaag caggtaatga ttttattcta cgttgtcggg ttatccagct
     7081 tgcaaccgtt ccttgtgggt aggcatataa ctcacaaaat tgttctacag tgattcctaa
     7141 attcttgata atgtaaacat tgatcgggtg cgagtaaaca aatgtattga tagacatggt
     7201 gcgtaagcct actttctttt attattgcgt ttgcaataat agtttaacac acgcattatt
     7261 ctagtatcta ctcctatttg taaaaacaaa aaaggattca tagagataac tctatagaat
     7321 ccgtaaaata ccttatatat ataacgggaa gatataaaac ctaaaattat gataacctgc
     7381 tgcagcttct acatagaaag agaagcgctc aacaccaacc tcatttatca aacgttggcc
     7441 ataaccccaa atctcttctg atagctgatc aaaggttata tactttagct catattgctg
     7501 gataatgttc attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt
     7561 tcgtcgtagt gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc
     7621 ttgccaatga tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat
     7681 actgatctat tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt
     7741 tgttcttttg ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta
     7801 tgatcagata aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt
     7861 tttaattccc ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct
     7921 agcgccttct aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat
     7981 cttgtcaata attttatcta aattttcttc gtcaatttgc ttttgtggat cactaaataa
     8041 atccagctga agcgaatcgg tgtacacaag cttgctatag gttattccaa catgccttac
     8101 ttcttgtcct tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt
     8161 attatctgtg atagggatct tcatctggtg tgaaaaccct ggtctcgttt ctaagatcga
     8221 cgtgccaatg tgtaaatgga cacaacctgt tttacagtta tgctgcctaa tgcgtatcgc
     8281 tacttgttcc gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg
     8341 tggtaacact tgtgaatttc catatgattt ttcctttgtc ggttctggtg ggattgctat
     8401 atctgttcga tcgatcccat tagcatggaa gtacagctgt aagccaatca cacctagtct
     8461 attcttaatc gtataaggat tccagttagc aagatctcta atgctcataa tccccatctg
     8521 attgagtctt tttttcattc gagagccaat tccccaaaag tccgtcattt caggaatatt
     8581 ccatactttt tcaggaacgt tttcgtacgt ccattccgca acaaatcctt cattatgctt
     8641 tgcttcgttg tctaaggcta gtttagccaa aaggggatta tctccgacac ctactgtagc
     8701 aatcaatcct agctcttctt taatattctc ctggatcatt tgagccagct tctttctccg
     8761 ttgacttcgt gttccttcag tcgtaaaaag attcagtgat cgggtcactt ttaagattga
     8821 ttcatcgatc gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt
     8881 tacctgcata tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt
     8941 aggaaatggt tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt
     9001 tgcttcagga gaagaagcta atatcaatcc tgaaccagta ttatcagctc gactcataac
     9061 aacaagttct gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa
     9121 gcttttcata tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa
     9181 taacactcca ttctttcaca ttatacaaac atatgttcga tattgtaaag aagaaatagc
     9241 taaatacata aaaaaagaag cataggtatg ctatcaccct gcttcttctt ttgatttgta
     9301 tgatcaattt attctatcac tttactaatt aatttgaaaa tctaataaaa actctcactc
     9361 taaaagagtg agagactgca aattagagta cggacttttt tggagttccg ttctttaata
     9421 ttaacaaatg aataaaatcc ttacaacatt tgagaataag ttatcagtag acacttacaa
     9481 aaaattctca tactatttcc tccatcatta gtttttgtct atataaggtt taccctaaat
     9541 agacactggt ataacattga aaaatatggc ttcctcgtgt atgattaggg tgtattttaa
     9601 atagttgcag aaagtaggta aaagttttga gagttgcata catacgtgtc tcatcgatcg
     9661 atcaaaatga acaacgccag attgaagaaa tgaaaaaatt cggtgcagag agaattttca
     9721 tcgagaaaca atctggcgca acgattactc atcgacctgt tttccaagaa gcattagatt
     9781 acgtccgaga tcaagatatt tttattgtgg aagctattga tcgacttgga agaaattatg
     9841 acgagatcat cgcttcagtc aattacttga agaagaaaaa tgtgaagctg atcattacta
     9901 gtttaccgat catggctgaa gcaattggca atcctctcct ggataaattc attaaggatc
     9961 tgatcatcca aattttggcc atgatcgctg aacaagaacg gactgaatcg aaacgtcgcc
    10021 aggcacaagg aattaagatc gcaaaagcaa acggcgtcta caaagggcgg cccaaattat
    10081 acagtgcaga cgcaaaagat ccccaacgtc gccttgttta caaaagcatc gttgaagatc
    10141 ttaaaaatgg tgttgcgatt gctaagattg ctaaagacta caatgttacg agacaaaccg
    10201 tgtatagaat aaaaaaagac agcatggtca atgacaaata gttgatcatg ctgcttttat
    10261 tatcttctca tctttaattt cctacatata attactatct ataaaattaa gtcttactca
    10321 gaacagataa agcataaaat tccaacaaac cattttttac ttaactaaat aaagagtctg
    10381 ttaatataat cttcacttat ttacgttaat cccctactgt atttgttggt tccttatcta
    10441 tattttctac aaaatcctta ttatcttgtg atttagcttc gtataattct ttgtatgtcg
    10501 acacattggt tatactaatt cctatagcta gttcttgaga ctctactttt ctctctagct
    10561 cctttgacaa agtgatttga gatttatttg gttccgttgg agtcaattct atagattctt
    10621 cataaaaatc tctatacata aagctatccc tgaataattc atagctttaa ttctttggca
    10681 cattttattg aaatatgtat cactaatatc cctatcaact gattttgact aaaaagttac
    10741 ttcaaacatt cactgttcaa aaatattgag gaataaattt tgggtgtaag gcattttgag
    10801 catacttctc cctggataac ttcccagtaa aaaaatcgtt agattgttgg attagatcca
    10861 ttgactggct cgcctcaggc gagcaaagac cctgtagaat tcattctgat acacatgata
    10921 actagataat ttgagataga ctcgtctacc cgtttggact aatttcccag caactttcag
    10981 aaacttcaat cgaatagaat gaatggtcat tcccttttgg acttcttcaa agccaatcgt
    11041 tcttaagaag ttgactaagt tgtaagctat caagctgagc atcattcgga catgattctc
    11101 caaaaagcga ggactgtctg ttttgtcaaa gtaaaagcca gctttcgctt ctttaatgaa
    11161 gttctccatt gtgccacgtt tggcatagat agaaaagatg gtatcaggag aaacattttc
    11221 tgatagattc gtcacgataa attcatgtcg aaagagtagt tcgcccgctt cacgtgttga
    11281 gcgtatacac acgcgacgac tttgtgacca ggattgtgct tgataagtgg tcgagaagta
    11341 ctgaacttct cgttcttccc acttttgatt atcgccataa agtactgatt tctcagctat
    11401 ttgacctagt ctacgattat tcttcagtcg aataacataa tgactctttt ttgattcaca
    11461 cgaatcatac acaccaggtg tagcgaaccc gctgtctcca cgaaccaaga tgtcagtgtt
    11521 tggtagagag tgattatagt gctctaataa aggtgtgaga aactccttta cgccttttga
    11581 tgtatattga tttcctgaac gtagttcagc ttttaagaag tcaccagtca atccgtcaaa
    11641 agctaccaat ggatggtaac cataggtttg gtagtgtgta ttataattcg tttgttcttg
    11701 gtgaccaaat gtatctgaat gggtcgaatc taaatcaatg attaattccg tatcattacg
    11761 gatgaggcgt gctttatcga taagttcttg gttcaaagct tgaagttcat ggatattctc
    11821 ctcagatagt cgatctaaaa atcgggaaag tgaagattga gaagcgagtt ctttcctatc
    11881 taaaacagct ttaaacacag gatcttgtct caggagatta gctgcagaat cagctgagta
    11941 accagcaatt aattgcataa tgaactgctc aagtatggat aagttgtcat gagtaaaata
    12001 cgctcgttcg tcttcaatgt gaatgtgttg cttagccagt tcagaaaaac caaagatgtt
    12061 catcagctct ttcactagga cgagacccga atcactcgat aattgaccac ctgtatgaga
    12121 aatagtgata tttgaattga attttacttg gtttttgtgt aagctagtca tgaaaagaac
    12181 tcctttcttt tggttggttt agtcacttta accatagcag aaaggggttc ttttttcatc
    12241 acttaacggg tgaagatgaa aaagtaattg taagctgccg tgaggcagtt tcacatggtt
    12301 ttaattaaaa gtatgaatta ttcaggctat cattaatttt ataaaaaaaa ttaaatgttt
    12361 ttagcactgc catataacat tcaaaacatt cttctatagt tggtttactt ccttgaggag
    12421 aatgaaccaa tttattacgt ttttctatga aatttttaat ttcctttctt atttctttcg
    12481 gaaactcaat attaaagtac cctttaaaca tgctccctaa taatttgtct acagggggag
    12541 attgtaaatt ctcaaatatt agagttaaat caggtttctc ttgttgataa aattccttta
    12601 cccctatttc acaggctgta attatcgaaa taaacctatc tctagtattt gatatatttt
    12661 tacttctttt aaggagtata agagaaaagg ggatactttc gtgtccatgc atgtaattaa
    12721 ctaattgttg agcttcagaa gttatatctc taattatata gttaacggaa ttaggaagtg
    12781 tctttaactc taatgaaatt tctatccaat tactatcttc taatctgtat atgctcgaag
    12841 tataatttga ttcgtcagca agcatcgcta catcccaaac actgatcata aaatctttta
    12901 aacgttcaat catttcagca atattgctaa aatcagctaa tttttcttta gaataaaaaa
    12961 aaacatttat atcagaatca ataaattcta tttttttatt actatatcgt catcattatc
    13021 ttgaccattt atgtttattg ttccctgagt ggggagtact tctttcaaat tcaagttaaa
    13081 tttatattcc attacttctc ctccaatata taaaaattac ttaactgtat ccaaatttaa
    13141 tatgtaaata aatcattaat ttttagctaa attctatgag aagtttattt ttgttgtttt
    13201 tgctaattaa ctaaaactag tacaaaaaat ttaaaataga ttattaaacc tattgcttat
    13261 tctattcagt catatatata agcgtcatcc tttagtaact aacatcccac actacaatag
    13321 tattataaca tatctattca acttcaaatt gttgaaattt aagccattta tatttacttt
    13381 tcctcaactt tagaaatgat tttactaacc ttatatccgt aatacgcgta acaaacacat
    13441 tcattaataa caatcaacac taagctatat tagcttttta aatgactagg gtaaataaaa
    13501 taaggatcaa aaacttttaa gtttctgacc ctttccttac ttccgattgg ttaatagtga
    13561 tcttttgcag aataaataaa tatcgtttca ttttcaactc tatatatcag tctatgttca
    13621 tctgtaattc ttctggacca ttttccagat aaatcatgct ttaatggctc aggttttcct
    13681 aatccagcaa agggggaacg atcgatatct tttattaact tgttaatctt ttttatattg
    13741 cttttgtttc cttgctcatg ccaataaaga taatcatccc aagcatcatc agaccaagcc
    13801 ttaatcatca gattcaacct cgattaagtc atgtgtttta aatgcacctt tggagaattg
    13861 ttcatctcct cgacgaattt tttccatgac gtaattatta gaaagtgttc tcaacgtttc
    13921 ttgcatagaa tcataatctc tttttgataa tacaacaact gtatcttcta catctttact
    13981 tgttacaata agtgtttcag catcctcatt aacttgtttc atataactac gtaaattttg
    14041 gcggaaattt gaataagcta ctgcttccat tcctttcacc ccttatttat ttctataaaa
    14101 caattgtaca ttatattgta caattaagca aatgattaat attctaactt cttataatta
    14161 aaagtgctat cacttttagt ttttaggata aaaagtgacg tcactttttg agtgctggta
    14221 cctcaaatcc tgctttttct tgggcaatca ataaatctaa cgcaatacac ataatcctgg
    14281 attcactttt gccgtacttc tgctttagtt gctgcaattc tttttgtctc ttttcatcca
    14341 acgtaacggg taaccgttta tttcctattg caattggcat tagtactctc tcctttcatc
    14401 gaaataaccc tatgaaaaat atggctgcaa tcatcttgaa tagtagactc acaagggcta
    14461 atacaaagcg ccaaaagatc aaacaaaata ccagtattgc caaaaatact acgaagttta
    14521 aatgcacagc tgcagcatgg cgcataagta tttcgccaac aaataggact aacaatagag
    14581 gaatgatttt attcatatgg atctccttct ttctcttagg ttatcgggtg ttgcccgctt
    14641 atttcgcacc acctaagcgg cgggggcggt tggagcgatt ggtgcgaaat aagaaccatt
    14701 cccttagtta ctaggttttt tgtccttatt tcacacattc tcacttttcg gtataaatga
    14761 ttattgcctt tttttccttt caaatcgttg atatggcatt cgtttacggt caagttcatt
    14821 ttggatttct tctgtatcgt cgtaagtata ggtgtctaaa aaatcagtta aagtcgtgta
    14881 ccagtcgtcg cctgggttat ctacttcttc tacatattcc ctcaaaaatg cttcgggtac
    14941 agcgagttca taatccattc ccattaacac gatagattcc gttccacacg tcaaaaatct
    15001 agtaaataca aggtaataat cgtctatcgt cgcatctttg ctgtttagct cttccatttc
    15061 ttcttccatt aattccatgc tctcaaaaat tgaataatat tctgattctg agtaatagtg
    15121 tttcctgcaa atcgtgtagc tgacaaagtt ttcgaccagc tcactccttt ctaggtaaac
    15181 attcatgatg tatttttctg tttctagtcg tagaagctcc gttccttttt ttaccgtttc
    15241 aggacgacgt ttatacacgt ctaaacgatt atggctgact gtgaccttcg tttgactcgt
    15301 ttcactttcc aaatacaatt gttcttcggg ttctgttgca aagttttaaa tctactatca
    15361 aataaggtag aataatagaa aaagatagca ggaggaatga cgatgaatca ttttaaagga
    15421 aagcaatttc agcaggatgt gattattgta gccgtgggct actatcttcg ttataacctt
    15481 agctatcgtg aagttcaaga aatcttatat gatcgtggca ttaacgtttc tcatacgacg
    15541 atttatcgtt gggtgcaaga atatggcaaa ctactctatc aaatttggaa aaagaaaaat
    15601 aaaaaatcct tttattcatg gaaaatggat gaaacgtaca tcaaaattaa aggaaaatgg
    15661 cattatttgt atcgagccat cgatgcagat ggtttaacct tggatatttg gttacgtaaa
    15721 aaacgggaca cacaagcagc ctatgctt
//
LOCUS       DADVXV010000071        14995 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.072, whole genome shotgun sequence.
ACCESSION   DADVXV010000071 DADVXV010000000
VERSION     DADVXV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.072"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            10..2382
                     /locus_tag="KB969_002126"
     CDS             10..2382
                     /locus_tag="KB969_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870090.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2443..3903
                     /locus_tag="KB969_002127"
     CDS             2443..3903
                     /locus_tag="KB969_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBB6870091.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3914..6118
                     /gene="topB"
                     /locus_tag="KB969_002128"
     CDS             3914..6118
                     /gene="topB"
                     /locus_tag="KB969_002128"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6870092.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6134..6283
                     /locus_tag="KB969_002129"
     CDS             6134..6283
                     /locus_tag="KB969_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870093.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6358..6951
                     /locus_tag="KB969_002130"
     CDS             6358..6951
                     /locus_tag="KB969_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBB6870094.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6964..7863
                     /locus_tag="KB969_002131"
     CDS             6964..7863
                     /locus_tag="KB969_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBB6870095.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7866..8363
                     /gene="ssb"
                     /locus_tag="KB969_002132"
     CDS             7866..8363
                     /gene="ssb"
                     /locus_tag="KB969_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBB6870096.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8729..8989
                     /locus_tag="KB969_002133"
     CDS             8729..8989
                     /locus_tag="KB969_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870097.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9434..9640
                     /locus_tag="KB969_002134"
     CDS             9434..9640
                     /locus_tag="KB969_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBB6870098.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9688..9891
                     /locus_tag="KB969_002135"
     CDS             9688..9891
                     /locus_tag="KB969_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870099.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9907..10344
                     /locus_tag="KB969_002136"
     CDS             9907..10344
                     /locus_tag="KB969_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870100.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10337..11044
                     /locus_tag="KB969_002137"
     CDS             10337..11044
                     /locus_tag="KB969_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870101.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11424..11603
                     /locus_tag="KB969_002138"
     CDS             11424..11603
                     /locus_tag="KB969_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870102.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11928..12191
                     /locus_tag="KB969_002139"
     CDS             11928..12191
                     /locus_tag="KB969_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBB6870103.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12185..12535
                     /locus_tag="KB969_002140"
     CDS             12185..12535
                     /locus_tag="KB969_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6870104.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12559..13173)
                     /locus_tag="KB969_002141"
     CDS             complement(12559..13173)
                     /locus_tag="KB969_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6870105.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13487..13909
                     /locus_tag="KB969_002142"
     CDS             13487..13909
                     /locus_tag="KB969_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870106.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13919..14122
                     /locus_tag="KB969_002143"
     CDS             13919..14122
                     /locus_tag="KB969_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870107.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14333..14917
                     /locus_tag="KB969_002144"
     CDS             14333..14917
                     /locus_tag="KB969_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6870108.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5524 a         2431 c         3043 g         3997 t
ORIGIN      
        1 ggaaagaaca tggcagaaga aaaagaacca ctagacaata gtcgtttggg aaaatccaaa
       61 agaaaactag tacgattgca aaatgaatta aacgaacaaa ttgaaaagat gtttgaacac
      121 caaaaaatga cgaacggtca accaatgaac gacaagagga atggccgttc atggtttaac
      181 cagcaagaac gaatcgaaaa taaagtccaa agtctgagag aagagatcaa gcaacaagaa
      241 gaatacgtgg aaaagcttga aagacaagaa gagctaaagg aaatgggcta taacaagtac
      301 ggcggactgg atatgacgat cgataatatt ccaagaatca aagaagaaat cgaacgcttt
      361 gaaaaaggtg aatcggcttt ttcagccgcc acgatccgaa aataccaacg gaagttggaa
      421 acattagaac agctgaaaga aaaatcagaa aaaggaaaag aaaatatcct ccctgaagta
      481 caagcgatca ttgacagcgg acgagtgacg caatggaaaa aaaatccaac catttatttt
      541 ttgaaaggct atcgaaaagt tgctttagaa ctgaatgaaa acgggggatt tgaggaatca
      601 aaaaaatacc aagccacgtc ggaagaggaa aaagcagctg ttcgtgaatt acttgaagag
      661 gctagaccaa ctgattctat gaaggagaaa gaaaacgatc atttctatcg agtagaattc
      721 aacgaaaatg atccagaaaa aggattgaaa agttatggtg gggagatcgt aacattcgaa
      781 ttgatcgatc aactcaaaac attggataac caatacgccg cagaagcagg ttattataaa
      841 ttctattttg aggaagtgaa gaacggagaa gtagtcgatc agatccgaat ggatctaggg
      901 gatggcgtca acagtaatca accaatctat ttagagttag caaaattgtg cgaacaagta
      961 cctgagaagg aacaaaaaca atcggtcaaa aatgaacctg tttcgaaaga acaaatgcag
     1021 tcgaaagaaa caaaaacaaa acaaaagggc tatcaaaaac gaacggcaga agagattaaa
     1081 caagaagtta aatccctttc gcaacaggca ctggatgcgg tgaaaaagca tacccattct
     1141 cctgaagacg tcaaagaact tttgaacttt atgtctcgtt ttccagaacg atcctttaga
     1201 aatcaattat tgattgagga acaatttcca ggtgcaacgg cttgtttagg tcgtgccgcg
     1261 ttgaaaaaag aaggaatcta tatcaaaaaa ggggaacaag ggaacaagat ctttgtcaga
     1321 aaaacggtca aagggtttta tgagaaagga cgtggctttg ttcgagaaac agaagctaca
     1381 ccagaagata aaaaacgaat cgaaagtggt caaatcgaag tgatcaaaaa accttactat
     1441 acgattgaaa aagtgtttga tatcacacaa acacagttaa aacctgaaga ctatccgaaa
     1501 atctttccga accgtgtctt tgattttcaa ttggataaaa aaggacagtc agaacttcaa
     1561 gctgggattc aagcggtagc caacaatatt ggaatacaaa ttcgagatat gacagaaagt
     1621 gaagtctatc aaagagaatt aggacaagca cgtggggcgt atgttcgtaa cgaatttact
     1681 ggcgaagaag aaatcgtcat gaatactcga aatactccta cgcagcattt agctacaagt
     1741 attcatgaat tagcccatgc aagaatgcac aaattttcag aattagatac cgcaactaaa
     1801 gaattgcagg cagaaatgac ttcttatatt gtgtgcaaac attttggaat ggacacgtcg
     1861 gagaaagcta ttccttatat tgcagcatgg acgaagaatg gtcagacgtt ggatgataag
     1921 gaagctgcgg aacgtgggaa aatcatgaat gatgtcagcc gtgtcgcaaa tgaattcatt
     1981 caaaccattt ctaatgaaat caatcaatac agagaaagag aaccagagat ccaaccagca
     2041 gaagtgaagc aggagcataa aaatacttta gaaacgccag agaataagaa tattgtgccc
     2101 gttggttcac tttggatcga caagaaagac gggaaagtaa tggaagaaga tacgggtcga
     2161 acgttacatt tgaaggatgc ggcgtttatt gaagatccgc agcataatca agtaatttta
     2221 aaaggaaaaa gttatggaaa agagatccaa acggcgttac cttcagaaga atttgcgcta
     2281 ggaaatccat tccgattttc acttgagaca gtgtcagaag tggcaaaacg aaaaaatgaa
     2341 atctattatg aacaacaatt gtcacaaaaa gaacgtgtat aaaacaagta aaaaagacta
     2401 tctgaaaaac ggatagtctt ttttcttttg ggaggtttta aaatgaccga gaaaaaaatg
     2461 agtcttattg atcgatgtaa acagatcgat atagtggatt ttgctcgaaa caatggaatg
     2521 gctgtagtca ataaaggacg agattatcgc ttagaagacc atgattcatt tgtttttgat
     2581 cgaagaaaac aacgttttta ttggaacagt caaaatatta gtggcgacat tattgaatta
     2641 gctaaacttt ttttcataga caaagagatc caagacccta agcaacaatt taaagcagcc
     2701 actgatttta ttctaaagaa tgaagacaaa acagaacgag tggaaaatct tcattttgaa
     2761 acagaaaagt acaaagatca ccccgttgat tatcaaccac tcacagaaaa aggaaggaat
     2821 tatctgaagg aagaacgaaa actaccagag tggctgattg attatgcaga aaaagaaggg
     2881 ttgattgccg aactaaagcc aaaatatgaa cggcaaaatt tcttagttcg agacgatcgt
     2941 ttagatcatg cggtcgcctt tttatggaaa gatccacaga caaaagagac agtaggggcg
     3001 agttatcaag gaacgttcat tgattatgaa cgttttggtg agagaggcac atataagcat
     3061 atagataaaa attcgacagc gaatcatggc tttaacctaa agatcggtga ccctaagcag
     3121 ataaaatttt ttgagagtag tattgattta cttagctatg ctgcactgaa tcgtgatcag
     3181 ttaaacgata cgtggttagt ctctatggaa gggttaaaac accatgtgat cagtcattat
     3241 tttggtgagg cagtatctga attgagaaag aaacaagcct ttcctcaatc catcgagatt
     3301 tgtgtggata atgaccgtgc aggacatatt ttctacgaaa aagaacaatt aatgggcgca
     3361 gtcgatccat ttacgaatca gaaagtacgt tgtgaacgag gaatcgctaa tgattggcaa
     3421 gtgccaaaag aatacaaaat catttatgaa gaagtcgcaa aagaagaaaa ggtcacacca
     3481 gaagctatta tggccataca caagacagaa aacaatctgc aattaacgaa ccaactggtt
     3541 tccgctcaca aagtaaatgc gttttttggc cagcagcttt ctgttaacga ttcaatagaa
     3601 gccattaatt tgaaagatat ttgtagagaa gtcgcaaaag aattaaaagt ttgtgaacgc
     3661 gtggatggta cgtacgattt tgatcgtttt tatcaagaaa aaggggatat taatgcgcag
     3721 attcttttct cttataaagc agaacaatac tacaaaggct ataaaaatca tgaacatgaa
     3781 tttgtacctg aagtaaaaaa ggactggaac gatcaattga agcatgagat ccagcaacaa
     3841 gaaatcagaa agcaaaaacg tgccatgttg tttcaacaag gcagacaaca agaaagggag
     3901 tgaaatcgtc atgatgaaaa ccgttatttt agcagaaaag ccgtcacaag cgaaagctta
     3961 tgccgatagc ttctctaaag ccactcgaaa agacgggtat tttgaaatcc aagatcgatt
     4021 gtttcctggt gaaactgtga tcacgtatgg ttttggtcat ttagtcgaat tagattcgcc
     4081 cgatatgtac gatgaaaatt ggaaacaatg gtcattagaa catttgccta ttttccctac
     4141 acattatcac tatcatgttc ctaaagataa gaaaaagcaa ttcaaggtgg tgaaacagca
     4201 acttcaatcg gccgacacca ttattattgc gacagatagc gatcgtgaag gggaactgat
     4261 cgcttggacg atcattcaac aagtaggcgc cgatcaagga aaaaccttta aaagactttg
     4321 gatcaactcc ttagaaaaag aagccattta tcagggattc cagcagttac gagacgcaaa
     4381 agagacctat ccaaaatttg aagaagcaca agcacgtcag atcgccgatt ggttaattgg
     4441 gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac caggaagctt
     4501 ttccttaggc agagtccaaa ccccaacgct ttacatgatt tatcaattgc aggaaaagat
     4561 tagaaatttc aagaaagaac cttattttga aggaaaatcc gaagtaatcg ctcaaaatgg
     4621 cgcatttgat gcgaagcttg atccgaatga aacccaagcg acgcaagaag catttgaaga
     4681 ttatttaaaa gaaaaggggg ttcaattggg aaaacagcca ggcatgattc gccaagttga
     4741 aaccgagaaa aaaagcgcgg caagtccacg tcttttttct ctatccagcc ttcagtctaa
     4801 aatgaatcag ctcatgaaag ctagtgccaa agacactttg gaagccatgc aaggcttgta
     4861 tgaagggaaa tatctaagct atccgcgaac ggatacccct tacattacgg aaggggaata
     4921 tgcgtatctg ttggatcact tagacgaata caagcatttt ttgagggctg aagaaatttc
     4981 gactcctatt catacaccga atagtaggta cgtgaacaac aagaaagtcc aggaacatta
     5041 cgcaatcatt cctacaaaaa cagttatgac agaagcgacg tatgaaagtc tgacaccttt
     5101 acaacaagcg atttacgagc aagttttaaa aacgacagtg gcgatgtttg cggaaaaata
     5161 tacctatgaa gaaacaacga tcttgacgca agtccagcag cttcagttaa aggcaatcgg
     5221 aaaagtaccg atagatctag gttggaagaa gttatttggc aaagagagcg acggaaaaga
     5281 gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga cggtagatct
     5341 acaagtcctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta cgttgatcac
     5401 tgcgatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca tattgaaaga
     5461 agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct tgaaacaaaa
     5521 ggaatatatc aaggtagaga aaaataagct tgtggtgacg aataaagggg ttttgctttg
     5581 ccaagctgtg gaaaaagagc cgctgcttac gagtgccgaa atgaccgcca aatgggaaag
     5641 ctacttgtta aagattggag aacgaaaagg aacacaaacc acttttctag ccaatatcca
     5701 aaagtttgtc tctcacttat tggaagtcgt cccaggacaa atccaatcca ttgattttgg
     5761 atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc gtcatttagg
     5821 aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg cagcttgtac
     5881 gtctgaagcc tgtgatttta aattatggac aacgattgcc aaaaagaaac tcacagcgac
     5941 acagctgaag gagattattc aaaatagccg aacaagccaa ccagtgaaag ggttaaaagg
     6001 tcagaagggt tcgtttgaag caacgattgt tttaaaagaa gacttcacta caggctttga
     6061 attttctgaa aagaaaaaaa cgaacttcaa gaaaagaaca cgacgcacga caaaataatg
     6121 gagggttaat cttatgcgta atacaacaca caaacaacaa gaaatcgaaa atcaaaaagc
     6181 caaaattcgt tcagaacaag agaaattacg tgccagtaaa agaagacttc agcaattaaa
     6241 gaaccagcaa cggattcaaa aagaaatcga attagatcga tagacattaa ccttgttaca
     6301 aatacactat catgatatat ttaatgtagt gtatttgtaa caaaaggggg gaagtaaatg
     6361 caagagaaac tgaaagaatt gttggctatt cgcgatggaa atttatctat gaaggaagcc
     6421 agaaaattag gaatcgcagc aaccactgta caaagattgg tgaatcaagg aaaattgatc
     6481 aaagttgatc gtggttatta tgtagaggat ggtcatggaa tagatgattt attttggctt
     6541 cagcaacgtt tttccagggg aatcttctct catgaaacga ctttagatat ttaccagctt
     6601 tctacgaata tgccgaaatt cattcactta acttttcccc atggatataa cgttgatcgt
     6661 tcaattacaa aagagcagca gttacaattt catttcgtga agaaagaagt ttatgaacta
     6721 ggaaaagtag agggaacttc ctttcaagga aatcctatta ctatgtatga taaagagcgt
     6781 acactttgtg atatttggaa tccgagatat gaaattgaat atgaaatgaa attagaagca
     6841 ttaaaagagt acatggaaga cccattgaga gatccaagta aattaagaga ttacatgaca
     6901 aaactacatg tagaaaaaga aatgaaatac cacatgcaaa gcttatattg atggaggaaa
     6961 aagatgacac cgacacaatt tgcagcaaaa acaagaaatt tagcaaagag gacaggatta
     7021 aatgcacagt tagtacaacg gcattttatg atggatcgtt taattgaaca aatttctgaa
     7081 tctaagtata aaaatgattt cattttgaaa ggtggctttt tattaggatc aaaatatgga
     7141 atcgatagaa ggacgacaat tgatatcgac acgacattta gaaatagcaa attaactgaa
     7201 gaaaaattga agagtatttt taatgattta actaggaaac ccacgaaaga aggtattgtt
     7261 ttctctattc aaggaatgaa ggaaacaaga gaagccgatt tttatcctgg atttcaaatt
     7321 aaattggtgg ctaatttaga gaaagtacgt gtgccattta aaatggacgt gacaacagga
     7381 gattctattt atcctgaagt agatacacac tatcaccaat taatgtttga agataaaaag
     7441 gtggagattc cagcttatcc aacagcacaa attattgcag aaaagctaag tgctacgttc
     7501 agctttggca cagataattc gagagcaaaa gattactacg acttatttac cattccgaaa
     7561 ctagaaaata tcgatacgaa agagttatac aaaagtgttc gaaatacatt tacaaaacgt
     7621 ggggatacaa aaccgttgtc cttttattat gaaagagaaa tggataagat cataggaaat
     7681 gactatttgg aaaagcagtg ggaaaaatat cgctcagtta acacgtttgc gaattccatt
     7741 tcatttacag atacagtcaa cgaaattgat cacctaatga aaagtgtgat caaaattgaa
     7801 aatcaagaaa gaaaacggca gtttaaaaga tcacaacaaa tgaatcaaga aatggagaga
     7861 taaagatgat caataatgta actttagtag gacgcttaac caaagatcca gatttacgtt
     7921 ataccgcgag tggtactgca gtagcgactt ttaccctagc tgtcaaccga aatttcacga
     7981 atcaaaacgg caatcgagaa gctgatttta ttaactgtgt gatttggcgc aaaccagcag
     8041 aaacaatggt gacattagct aaaaaaggta gcttgattgg tgtagttggg cggattcaaa
     8101 cgcggactta tgacaaccag caaggacaac gtgtgtatgt gacagaagtt gtggccgata
     8161 atttccaact attagaaagc aaagcagcga cagaaagccg tgcgcacgct gatcaatcgt
     8221 ccaccagtcc aagcaccacc acttttgaac aacgggatac agcgacgcct aataacaatg
     8281 gattgaacgc tttacagaat ccatttggga atccatttgg tggacaatca atcgatatta
     8341 gcgatgatga tctaccgttc taagtagcat tttctattgg ttgcatttgc tacggtttat
     8401 gttataattt agtcaacaaa aagaattttc aatctataac caaaaaccac tagctggcgg
     8461 gctagtggtt ttcttttacg tttctattat aagaattaac gggtaggctt actgtctttc
     8521 ttggcaaatt tacaatcaag ccatttgcag atatagtgcg cggctacttc tgccatgatt
     8581 gcaaaaacaa aatcaaaaag aattttcaaa cctataacct cctccccttg ccagattagg
     8641 ccggggtagc agacagcaag actattatag cataattgaa atatccaaat gattggattt
     8701 ttgctataat tttagcgagg tgattgtgat gaacaaatat gttggtttgc ttgataaaat
     8761 ccgagtaata aaaacgcaac cgttattggt tcgctttact ttacaaacga ttcatgaatc
     8821 gattaattgt gtagttgcag atattgaaat tatcgataaa ttgctaatta tggatgatgg
     8881 aaaatacaat attgccgtca caggtcactt caataaacga aatcagctag ttattgctag
     8941 catgtatgtt agaaatcccg atcattttac gcgatcgatg ggcatataaa aaaagaagag
     9001 ttgcaatcct aatgtaggac tgcagctctt tttgttttac atagaaacaa gaaaaatgaa
     9061 aaggcctttt taggaaggcg cgagcgcctt ctcaattgaa aaacctctct cactccaacc
     9121 gccaccgccg ttcgagaaga aaggaagtga acgttgcacg ttcactaaga taaagggtct
     9181 tgcaaagcaa gacaaaatag aaaaaacttc ctctcaccaa aaggttcgtt cctgttcgtt
     9241 atctctttat tgatttgcca gaccggcaac aagttgcctt ttatcaccaa aaagcgacaa
     9301 ggacaagggt aaatggcacg ctgcgcgccc ttgtccttgt cgcttttcgt tgattcattc
     9361 tggccaacaa atcaataaag aaagaactaa cgaaaggaag taaaaccttt cctaagagga
     9421 ggcagaatca atcatgcgaa agaaatttga ttattggggt gttcccttca gcgaattatt
     9481 cccaaactat catgcaccac atactgtcga atgcgattgt ggacaaagag cgaaatgtat
     9541 caaaagctat cgtttgtatc aatgtccaac atgcggaaaa aaatacacct tgtcttatgg
     9601 cgattatatt ttgattgatg agaaaggaaa gaaacgctga tgaaaacata acataaatta
     9661 ttgactgtaa aagaagtcgt tcaaattttg gtggacaaag aagtcatttc tgaaaaagta
     9721 gcagaagctt tacttattcc gcggtactgg acgatagaaa cccctttagt agaggatgca
     9781 ccgactatgc tatttgaaga cctagtgaag attgcaggat atgaactgca ttatcaagaa
     9841 aacatggaaa cttatgaaaa cgaatattgg ttaaccaaat tagagaacta aaaaggagaa
     9901 aaaaatatgg ctcaaaatta ctatgacgaa tttgtcaaat tacctttgga taaaatggca
     9961 caaaaaatgg aggatatgac attcctatac catgagacac gtgttccaaa aaaacattat
    10021 aaggaaagat tgtcggtagc tgtggaagaa atgattgaat caggtgtcga aatgaatctc
    10081 attgcgacgt actatcgaac actggaagaa ctgaaaaaac aaaatgcaaa atggtttttc
    10141 caagccttac tatgcttgga agtaggtgtc aaaccaagca ctattaaacc ttctgaatat
    10201 caagctttag aactaacgta tgggaaattt gtcgaaacga aaaaagccaa gactgtttca
    10261 agtgaatggt tagattattt tgaaaatatc aataagtatg gcgcctatta caccatgaaa
    10321 aaggaggaca acgaaaatga ataaggtgat ttatcaacta acaacggaag atgtgtcaca
    10381 ctttttaaca aacaaagaac atttgaatga agtaatcaga cggattcaaa aagactttag
    10441 ttgtatggaa gaaatgaagt actttattca aagagtcgaa gaacaattgt atttggaaag
    10501 tgaaacgagt caaacgaagg tcacagtcag caataattat ttagacgtgt ataaacatcg
    10561 tcctgaaacg gtaaaaaaag gaacggagct tctacgacta gaaacagaaa aatacatcat
    10621 gaatgtttac ctagaaagga gtgaactggt cgaaaacttt gtcagctgca cgatttgcag
    10681 gaaacactat tactcagaat cagaatatta ttcaattttt gagagcatgg aattaatgga
    10741 agaagaaatg gaagagctaa acagcaaaaa tgcgacgata gacgattatt atcttgtatt
    10801 tactagattt ttgacgtgtg gaacggaatc tatcgtgtta atgggaatgg attatgaact
    10861 cgctgtaccc gaagcatttt tgagggaata tgtagaagaa gtagataacc caggcgacga
    10921 ctggtacacg actttaactg attttttaga tacctacact tacgacgata cagaagaaat
    10981 ccaaaatgaa cttgaccgta aacgaatgcc atatcaacga tttgaaagga aaaaaaggca
    11041 ataatcattt ataccgaaaa gtgagaatgt gtgaaataag aacaaaaacc ttgaaattaa
    11101 gggaatggtt cttatttcgc accaatcgct ccaaccgccc ccgccgctta ggtggtgcga
    11161 aataagcggg caaagcccga taacctaaga gaaagaagga gatccatatg aataaaatca
    11221 ttcctctgtt gttcgtactg tgtattggcg agatacttat gcgtcatggt gcagctgtac
    11281 atttaaactt cgtagtattc ttaggaatac tagtattttg tttgattttt tggcgctttg
    11341 tgttagccct tgtgagtcta ctattcaagt tgattgcagc catatttttc atagggttat
    11401 ttcgatgaaa ggagagagta ctaatgccaa ttgcaatagg aaataaacgg ttacccgtga
    11461 cattagatga aaagagacaa aaagaattgc agcaactaaa gcagaagtac ggaaaaagtg
    11521 aatctaagat tatgtgtatt gcgttagatc tattgatcgc gcaagaaaaa gcaggatttg
    11581 atataccagc actaaaaaag tgacgtcact tttcatttga agaaacaaaa gtgatagcac
    11641 ttaattgttc ctactattta gaatattttc tatgtccttt ttattccatt ttgtatcaat
    11701 aactatgaaa tctttaaagt atccagatca atttttttct tacctgattc taaagatttt
    11761 gttttcttaa acatattatg atttcctttc gactattttc atataaatgt taacatagtt
    11821 tatggattca tggaatgtta atctaattta atagaaaagg ataattaagt atatacgttt
    11881 tttcttatgt atgttatact atgtatatac agaaagaggt gtctactatg gaaatgttac
    11941 ctataaaaaa atggggaaat agtaatggcc ttagattgcc aaagtatatt atggaatatc
    12001 ttggaattca tacagaagac aaagtgaaga taatacaaga agaagtaaac ggtcagaagc
    12061 ggctaattat cgaagcggct aatatagaaa atgaattaac aattgaacag ttatttgaaa
    12121 attacactga tgaaagaaat catgtgacga ttcaaaattt aggtgaagca gtaggtaatg
    12181 aaaaatggtg agaaaaccta gacaaggcga tattctatta ttgaatacag cacctcgatc
    12241 tggacacgaa cagacaggta aaagacctta tattgtttta agtcatgata ttattgcgga
    12301 ttatagtaac gttgttacag ttgctccaat ttctagtaca actagaaact atccgctata
    12361 tgtaaatata aactcagaat atgaaatgaa gacaacagga aaagtattat tagatcaact
    12421 aacgacaatt gattatgaag ccagagagtg tatttttttg gaaaaagcgc atgatagttt
    12481 agttgaggag ttattgatga aagttagaac agtttttcaa aaagtaagca aataaaatag
    12541 aaacagcagc atgatcaact attcgtgatt gaccatgctg tcttttttta ttctatatac
    12601 ggtttgtctc gtaacattgt agtcttttgc aatcttagcg atcgcaacac ctttttttag
    12661 atcctcaacg atgtttttat aaacaagacg acgttgggga tcttttgcat tggcactgta
    12721 tagcttagga cgtcctttat aaacaccgtt cgcttttgca atcttaatgc cttgtgcctg
    12781 acgtcgttta gattcggtac gttcttgttc agcgatcatg gccaaaattt gaatgatcaa
    12841 atctttaatg aatttatcca ggagaggatt gccaattgct tcggccatga tcggtagact
    12901 tgtgatgatc agctgcacat ttttcttctt caagtaattg actgaagcga tgatctcgtc
    12961 gtaatttctt ccaagtcgat caatagcttc cacaataaaa atatcttgat ctcggacgaa
    13021 atccagtgct tcttgaaaaa caggtcgatg agtaatcgtt gcgccagatt gtttctcaat
    13081 gaaaattctc tctgcaccga attttttcat ttcttcaatc tgccgttgtt cattttgatc
    13141 gatggatgag acacgtatgt atgcaactct caaaattttt acctactttc tgcaactatt
    13201 taaaaaacac cctaatcata cacgagaaaa ccagattttt caatgtcgcg gtcgtgtcta
    13261 gttagggtat accttatata gacaaaaact aatgatggag gaaatagtat gtgtcacttt
    13321 tctttttaaa tggcaatatt ttttgtaaat aaatgtcaat caagaaaatt taaacgatta
    13381 tgacattaaa aatatatttt atgaattttc tagtatataa cttgatttat ctgttaagat
    13441 ttattaagaa aacgttttct tatttttgat ttcgaggtga tagacaatga aaaataagtt
    13501 tattttatct ttaggtattt taactattgg aattagtgta actggaacta caattcctac
    13561 atttgctgat agtacaaatg aaccaactac tgtagtagat aataaccaag aattaactcc
    13621 tttagatagg aacggaatag ccattggtaa cccaactaac gacttaactg ttactgaaaa
    13681 ttatttaata gtttctccat tacttgctcg agcagcttct aaaacgatac gagtgacagg
    13741 aacgatgatt tttgataaag ttggttggcc ttctagacct cctcaatcac ggaattggaa
    13801 agaaaaaaga aatggttatt ggtactatgg aaaattgtat ttacaaagtt ataaatcagc
    13861 tggaaacaat tggattgcga cttattcagg aaccttaact agaaagtagg gattttttat
    13921 gccagaattt gtgaacacac caaattttta tcaagatagc gatattctaa gtaaaattaa
    13981 tttaccgaaa gaagaatcag ctttacaagt tcagcgaact ttacaggaga cacaaaaaat
    14041 tcaaaaatca atttctaatc tagaagattc tgaagaaaaa agaaaaaaaa gagaccaaaa
    14101 aacatatcaa aaagaaaaat aatgatttta aaaaaagagt gtctagtcga cattcttttt
    14161 ttctaattga aagtgttcat aaaatcaccc atttctggac actttctttt tttgctttat
    14221 ttttcaaaaa aacaattcat ttcatgttca taaacccata acaatatcta tgttcagtta
    14281 aactatatgg ataaagttat gttacaataa aattaatgaa ggagtgattt ttttgaaaat
    14341 aggatacgcc cgggtatcta ctggtttaca aaatttggat ttacaagaag acagcctaaa
    14401 taaatttggt tgtgaaaaaa tttttactga tcatatgagt ggggcaaaaa gtaatcgacc
    14461 aggattagaa atggccattg attttgttcg ctctggcgat acacttgtcg tttggcgctt
    14521 agatcgttta ggtagaaata tggaagattt gatttcaatc gtcaatcgac tgaatgagcg
    14581 tggtgtgagt tttcatagta ttcaagaaaa tattacgatg gacaaatcaa gttctacagg
    14641 acagctcatg tttcatttgt ttgcggcatt tgcagaattt gagcgtaatt tgatcctgga
    14701 acgatccgca gcaggacgag cagctgctcg tgcaagagga cggtttggtg gtcgtcctga
    14761 aaaattgtct gaacaagatt tggaattact gaagacttta gtggatagcg gtacacctat
    14821 taagactatt gcggaacggt ggaacgtctc aagaaccacc atttatcgtt atttggcaaa
    14881 aatggaggag aaaaatggaa agacaaattc tcattagttt ttgtcattta atgctgaaaa
    14941 tttttgccat ttatctagaa aagtgacaat agtatgagaa ttttttgtaa gtgtc
//
LOCUS       DADVXV010000072        14844 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.073, whole genome shotgun sequence.
ACCESSION   DADVXV010000072 DADVXV010000000
VERSION     DADVXV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.073"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..492
                     /locus_tag="KB969_002145"
     CDS             <1..492
                     /locus_tag="KB969_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870109.1"
                     /translation="SILNYSSVVNMVKEMNFQGTYSNEQMENKLEEFENFDYVPIGYK
                     KDQLLLKNHQVTEDGQVIYSSFSPNKDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSK
                     NATVLKQGGPFVTVKSESGINKVTIRYSYTFFSKISLFISIITLIVLLFYCIKLKIRT
                     SHE"
     gene            complement(759..1928)
                     /locus_tag="KB969_002146"
     CDS             complement(759..1928)
                     /locus_tag="KB969_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBB6870110.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            2132..3307
                     /gene="mltG"
                     /locus_tag="KB969_002147"
     CDS             2132..3307
                     /gene="mltG"
                     /locus_tag="KB969_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBB6870111.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            3443..3922
                     /gene="greA"
                     /locus_tag="KB969_002148"
     CDS             3443..3922
                     /gene="greA"
                     /locus_tag="KB969_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBB6870112.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            4091..4822
                     /locus_tag="KB969_002149"
     CDS             4091..4822
                     /locus_tag="KB969_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBB6870113.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            4819..5886
                     /locus_tag="KB969_002150"
     CDS             4819..5886
                     /locus_tag="KB969_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6870114.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            5893..6525
                     /locus_tag="KB969_002151"
     CDS             5893..6525
                     /locus_tag="KB969_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6870115.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            6665..7330
                     /locus_tag="KB969_002152"
     CDS             6665..7330
                     /locus_tag="KB969_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBB6870116.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            7358..7651
                     /locus_tag="KB969_002153"
     CDS             7358..7651
                     /locus_tag="KB969_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBB6870117.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYNPNLEEPTYHFKKQ"
     gene            complement(7719..8666)
                     /locus_tag="KB969_002154"
     CDS             complement(7719..8666)
                     /locus_tag="KB969_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBB6870118.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(8844..9647)
                     /locus_tag="KB969_002155"
     CDS             complement(8844..9647)
                     /locus_tag="KB969_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBB6870119.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            9793..10707
                     /locus_tag="KB969_002156"
     CDS             9793..10707
                     /locus_tag="KB969_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBB6870120.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            10755..11225
                     /locus_tag="KB969_002157"
     CDS             10755..11225
                     /locus_tag="KB969_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBB6870121.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            11310..11918
                     /locus_tag="KB969_002158"
     CDS             11310..11918
                     /locus_tag="KB969_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBB6870122.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            12052..12252
                     /locus_tag="KB969_002159"
     CDS             12052..12252
                     /locus_tag="KB969_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6870123.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            13006..14232
                     /locus_tag="KB969_002160"
     CDS             13006..14232
                     /locus_tag="KB969_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6870124.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(14340..14810)
                     /locus_tag="KB969_002161"
     CDS             complement(14340..14810)
                     /locus_tag="KB969_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBB6870125.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
BASE COUNT         5096 a         2265 c         2941 g         4542 t
ORIGIN      
        1 tcaattttaa attattcatc agtagttaac atggtgaaag aaatgaattt tcaaggaact
       61 tattctaatg aacaaatgga aaataaactt gaagaatttg agaattttga ttatgtacct
      121 ataggctata aaaaagatca attgcttttg aaaaaccatc aagttacaga agatggtcaa
      181 gttatttata gtagcttttc tccaaataaa gatgaaatta catttacgtt taaatcttca
      241 aaaggcaaaa caatagtttt acctgtattc cggtataaag gattaacggt tactgttaat
      301 tcaaaaaatg ctacagtact aaaacaagga ggtccttttg ttacagtaaa aagtgaaagt
      361 ggaataaata aagtaacaat caggtattca tacacatttt tttctaaaat ctcattattt
      421 atttctataa tcacgctaat tgttcttctt ttttattgca taaaattaaa aataagaaca
      481 agccatgaat gatttgctag cacatatttt agcaatctaa agatactatt ttagatttaa
      541 taggcccttt gtcaaataat gttggtaaag agaaatctta gaataatttg gacagaacag
      601 aaagaagaac acctctttct gttctgttta tttggaatta aagtctgtag caaaaattga
      661 tttttagatt tgtcccacac tctttcctac gtttagtcga gtactttttt taagcaaatg
      721 ctattcaaag aagtagtatt tgctatcttt tcatcatatc agctatttgc caacttagta
      781 gttccttcca tcaggtcata gatttggttt cttagatcag cagtaggcag tttgatagtt
      841 ttgtcagctt ttatattgct ttccatgatg atagcatcct gtgaatcttt gctaaatata
      901 gcagatgtat caaaagagtc gatatttcct tgcgacagga tataattatc tccgctatat
      961 accccaccac tatatggatg tccattcgca ttttcacgcc ataatgagaa gagtaagtct
     1021 ttggaaacta gttttccaga taaaacttgt gtaaacagcg tatttaaatc atagacggac
     1081 atactgatat taccagtccc taattcgtta tggatctctg tttcagattc tgtcagtggt
     1141 ttaaagtaat catcctcttt agacatttga taggatagtg catgattgga tgaatttttg
     1201 acttggtcat aaaattttgt atgctgtaat cctaaaggtt cgatgatatc atcggtcaat
     1261 aatttttcat acggttgatt tgttaatttg atcaaaattc cagtcaatat ggtaaagttc
     1321 aatgaatcat aatgagaggt ctgataatct gtaaatttta agtgctgaat cgcaaattga
     1381 acgacttctt catcagtcat cggtatggtt ggagaagcag ttcggtgcaa gcctgagcgc
     1441 atatacagca agtcacggat agtaatttgc tggctgccag caatttgtgg atagaattga
     1501 gccagcttag tatctaaaga aaggtgccca cgctcgactt gttttaaaat caaaagagta
     1561 gtcaatgctt tttgaaccga accaatctga taataaagag aaggatcatt tggttgttgc
     1621 gtgagtttat tcgcatagcc atagcctttt tccatgatga tgcgattatt tttctttacg
     1681 taaattgagc caatataatc attttttctt aatagttgat cgattttttc aacgagctgt
     1741 tgttcattgg tagtcagtat caactttttt tgagctgatt gagcatgggc aactatctga
     1801 gagtgttcat tattgtaaaa ttgccatcca agaatagttc ctgtagagaa cgcactaagg
     1861 ctaaacaaca cgacaacgat cattaaaaat gaatattttc tttttttagc atgttttcct
     1921 tttttcataa tagtttattt agtctccttt cttttttaca gaaagaataa agctaaaata
     1981 gcttgtatct tgataacatt tattttaatc ttatagtaat ggatttacta cttacatttt
     2041 tgatagaata tttaaataaa atcattcacg ccaattcaaa tatcatgtat aatgaataaa
     2101 gttacgaact tgatagtaag gaggagttgt tttgtcagga aacaaacaac acccaagtaa
     2161 agataaaaaa gaagccagta aggcagctac agcagatata atcgacaagc ggagaaatct
     2221 gcgtaaaaaa gaagataaga ttgtgaggaa gatcatttta gtgattgctc ttacattatt
     2281 gattattggc ggatttcttg gatttaccgt gtatcgttat gtagatagcg ggttgaagcc
     2341 tttagataaa tcagatgacc aattagtcca agtcgagatc ccgagtggct cttctaacaa
     2401 gcagattggt gagattttgg agaaggacaa tattattaaa agcgggattg ttttcaatta
     2461 ttatacaaaa tttaaaaatt taactggctt tcaagctggc tattatcagt tagcgcctaa
     2521 tatgactctt gacgagattg gcaaacagtt gcaagaaggc ggtacttctg agccaacaaa
     2581 agttgcagat gggaaaattg ccattccaga agggtacgat atcgatcaga ttgctgaacg
     2641 ggtagcgaag gtaactggta aagacaagaa agaattttta gatttagtga atgatgagac
     2701 tttctttaac gagttgcacc aaaaattccc agaactgttg gaaagtgcat ctaaagctga
     2761 gaacacaaaa taccgtttgg aaggttactt attcccagcc acatatgatt attacacgag
     2821 tacttcgctt aaggatctag tgattgaaat ggtgaacaag acgaatacgg tcatgcaaaa
     2881 ctattattca gctatcaagc agaaaaattt gactgtacaa gaagttttaa ctctagcttc
     2941 tctagttgaa aaagaaggcg taaaagaaaa tgatcgtaaa aacattgcac aagtcttctt
     3001 taaccgaatc aaagcaaata tgccacttca gtcagatatc tctgttttat acgcattagg
     3061 tgaacacaaa gaattagtga cgtatgaaga tacagctgta gattcaccat ataatttgta
     3121 taccaatacc ggctatggac ctggaccttt tgacaatcca agcgaagagg caatcaaggc
     3181 agtattagaa ccagcagaaa atgactatta ttatttcgta gcagatacga gcactggaaa
     3241 tgtttatttc gctaaaactt atgaagaaca tatggaatta gtggaaaaat atgtaaataa
     3301 ttcttagaaa aacaggctct agacattgat catttttaga aaaacattta catttgaaga
     3361 aaagcgtggt aatctttttt ggactatatt cctcaaaaga ttaccttttg cggtatttta
     3421 tcgaaaaaag gagacgttac acatggtaga gaaagtttat ccaatgactc tagaaggtaa
     3481 agaaaaatta gaaaaagaat tagaagaact aaaaacagtc aaacgcggag aaatcattga
     3541 acgaatcaaa attgcccgcg gtttcggaga tctttccgaa aactctgaat atgaatcagc
     3601 gaaagatgaa caagcatttg ttgaaggaag aatcacaaca attgaaaata tgattcgttt
     3661 tgctcaaatc atcgataacg acggtgtaga tgcagatgag gtatcaattg gtaaaacagt
     3721 tacattcatc gaactaccag atggagaaga agaagagtac acgattgtcg gaagcgctga
     3781 agcagatccg ttttctggca aaatttccaa tgattctcct attgcgcaag cattgattgg
     3841 caaacgtaaa aatgatgaag taactattgc tactccaggt ggcgatatgt tagttaaaat
     3901 cgtcaaagta gaacaagcgt agtctgactg aaagatctag agagttcatc ttactgatga
     3961 tacactctag atctttttct ctttgtgtat tttagatttc aacaaacgat cttacatcta
     4021 aagtcctata gccaacagtt aaaaaaatag gtatgatgaa atgagaatgt gtcaggaggg
     4081 agaaagagcg atgaatagtt cttggcgttt ttttgtggta gttgaagcac tactgctgtt
     4141 atttgctgtt tggcaaatcg taaacaatac tggacttttg cttttagtga tattcggtat
     4201 tttcaatata tatctagcta tgcgcaaaca tcctcgtact aaatttcaaa attttcaatt
     4261 gatattagga agtttggtca ttttttttag cttagtcaac agtcctgctt tatggatgat
     4321 ggctgtattt gccgttttat ttattggtct gaaaggtgta gagatttcag ggatagattt
     4381 aaccaaaaat gctttttggc gaaagaaaca gatcatgatg atccaaacag agcaattaaa
     4441 aacacataat aatgagcgga aaagacagca attattcggt aaccaacgta ttggaaacga
     4501 cgtctatgaa tgggacgata tcaacatcgc cgtcatttct ggtgatacta tcatagattt
     4561 gggcaatacg cttttgccaa aagatgataa tattgtgatt gtaagaaaag ggataggcag
     4621 aacacggatc ttagtacctt tgggcgtagc catccgatta gagcatgcga cattagtagg
     4681 aaatgtcttg tttgaagaag agcaattttc tttgaaaaat gaacaaatca aaatctacag
     4741 cagtgattat gatgaaaacc ctcgtagatt gaagattatt actaatacct tgattggaga
     4801 tgtcgaggtg atacgaatat gatgggaaaa atatccagag cgatgctagc tgtttattcg
     4861 gggattgcgg ctttccttat tattctattt tcacttttca cttattttta tgccagcaat
     4921 caaagtcatt ggtggggaga attactgcgt gcacgtttat tatatgttcc gcttatcttc
     4981 catttgttag ccatttcctt aggtgtagga ttaattgtct ttctattatt atcacttatt
     5041 caaaagacaa aatacgggaa aatcgaagaa aagctgcgtg cactttcttc tggcaattat
     5101 gaatccaaat tgttgcttct tccgatccca agtgcatcgg acgatttata catcaaagat
     5161 attgataagg aaatcactaa gataaaagaa aaaatgattg aagtatctag tgaattacaa
     5221 attgtaacga gccgtcccca atatgtagat ggacaaacca aagaagaaat tttagaatta
     5281 gaaagacatc gattagcccg tgagctgcat gattcagttt cgcaacaatt gtttgcagca
     5341 atgatgatga tgtcggcatt gacggagcaa gcagaaaaaa gcgagacacc agaaatgttt
     5401 cgcaagcagt tgaaaatggt agcagagatc atcaacgctt cccagtctga gatgcgtgcg
     5461 ctgcttcttc atctacgtcc agtcaattta gaagagaaaa gtttaaagca aggtatcgag
     5521 cagttattga aggaattgca aaataaaatc cagatttcgc tgaaatggga tgtagaagat
     5581 gtaaaactat ctagttccat tgaggatcac ttgttccgaa tcgttcaaga attgttatca
     5641 aatacattaa gacatgctaa agccaatgaa ttagaggtat atttgcacaa aatagacaat
     5701 aatcttttgt tacgtattat tgacgacgga acagggttta atatgaatga aacgaaaacg
     5761 ggaagttatg gattgaacaa tatcaaagaa cgagtagctg gtattggtgg aacagtaaaa
     5821 atcattagtt ttaaaggtca aggtacaagt gtagaaatca aggtcccttt gatgaaggag
     5881 gcatagataa ggatgataaa agttttatta gtagatgacc atgaaatggt gcgcttaggc
     5941 gtctcttttt atttatctat tcaagaagac attgaagtaa ttggagaagc tgaaaatgga
     6001 cgacaaggct atgagaaggc gatgacactt cgaccggacg tcattttaat ggacttagtc
     6061 atggaagaaa tggatggtat cgaatcaaca aaagcaatct taaaagattg gccagaagct
     6121 aaaatcatta tcgtaaccag ttttattgat gacgaaaaag tttatcctgc cattgaagca
     6181 ggtgcagcag ggtatttgtt gaagacctct accgcacatg aaattgctga tgctataagg
     6241 gcaacgcaac gtggcgagcg agtattagaa ccagaagtga caacaaaaat gatggaaaaa
     6301 atgagtcggc gaaatgagcc tgtattacat gaagaactaa cgaatcggga aaatgaaatt
     6361 ttaatgctga tttctgaagg aaaaagtaat caggaaatag cggacgaatt gtttattaca
     6421 ctgaaaacag taaaaacaca tgtttccaat atattggcta agctagaagt ggaagaccgt
     6481 acacaagccg ctatctatgc attcaaacat ggtttggtga aataaaaacg atgataaaga
     6541 ggataatcaa aagctgagaa aataactatt atttttcttg gcttttttac aataatgatg
     6601 cttgcttttg tttttgtaaa ggctttgtta tactgagaaa agaagatact aaaggaggaa
     6661 aacggtgaaa caaaattttg caattgtagg tcttggacga tttggcggaa gtatctgccg
     6721 aacactgatc gaagctggtc aagaagtact ggctattgat agtaatgaag atcgggtcaa
     6781 tgaatatatg aatatagcca ctcatgctgt tgtggcaaat gcacaggatg aaatgacact
     6841 tcgatcatta ggcataagaa atttcgatca tgtaattgtc gctattggag aagatattca
     6901 agccagtatc ttagttactc tgatggtaaa ggaaatgggc gtaccaaata ttttagcaaa
     6961 agcccaaaat gagtatcatg ccagagtact tgaaaagatc ggagctgatc gcgtcgtcca
     7021 tcccgagcga gacatgggaa taaggattgc gcataattta gtgtcaaaga atattttaga
     7081 ttacctagag ttgtcagata aatattcttt agcagaaatc cgagtctcca atcctaaatt
     7141 tttcaacaaa acattagctg aattaaattt caggcaacgt tttgacttaa cagtagtcgc
     7201 catacgaaga gtagatcaaa cggttatcgc ttctcctgca gcagatgaat atgttcgtga
     7261 aaatgataat ctactggtta ttggagagac aggcgatgtg gatattctag acgataagat
     7321 gaatcaatag aaagaaaaga gaaagtaggt tgttgggatg aaattaacgg taacgccaaa
     7381 agcacaaaag tggtttgact cagaaattga tctgccagaa acttacggaa tacgtttttt
     7441 tggaaaagtc tacggcaaaa cagaggttca tgatggtttt tcgattggaa tgtcagttga
     7501 acagccagaa catcctgtaa agaaagtgga aattgatggg acactttttt ttatcgagga
     7561 agcagatgaa tggttcttta aaggatatga tttacttgtt gattataatc ccaacctgga
     7621 ggagccaacc tatcacttta aaaaacaata aaaaaagaga gggtgacaca atttttgtca
     7681 ccttctcttt tttcttttga aaatattgtt ttcagctatt aatatcctgc agacaatttt
     7741 acttgattgg tttgaagctc atgggtggca aagtagcttt tcagattggt taaaaaaata
     7801 gccattaatt tcttttgaaa atcaggtgtc aaacctgcaa tgtgggaagt aatcagtaca
     7861 ttgtccattt tccaaagagg atgatcttgt ggaagaggct cttcctcaaa aacgtctaat
     7921 gctgcaaagg aaagttgctg gttatttaaa gcctgcacca gatcttgtgt cttaacagaa
     7981 gcaccacggc caacattgat gaatacagat tttggatcaa agtgttcaaa catatgctga
     8041 tcaaagagcc cagttgtttc ctccgttaga ggtaagatat tgactacgaa atctacttca
     8101 ggaagaactt cctttagttg atttaaagaa aaagtctttt ccattccttc tgctggatga
     8161 ccggatgtat tgattccata gcagttcatg tctaatgctt tgcatttttt tgcaatcatt
     8221 tttccaatat ggccagttcc aatgattagt atttttttcc cttggataga ttggtaatgg
     8281 accgatgaac ctaaccattt catgtcactc tgtgcctttt gtgcttgaaa aagaccacga
     8341 gaatacccaa ggatgattcc taagacatgc tccgtaatcg attcactgtg gatgccacta
     8401 ccatttgaaa gtaaaatatg tttctttgaa aaagtctcaa ggggtagctg atcaacacca
     8461 gctgagatag attggaccca tttcaaggta gaagaggcta atagtttttc ttggtagtct
     8521 gagttccagc ccaaactgat ctctacattt tgtagatcct ctggttgtaa ttctgtttta
     8581 aagatataac caggcgctat agtatggatt tcttcgataa attcatcacg aaatggacga
     8641 tctgcataaa tgattctttc tgacatagtt aatttcccgc ctttctttac tctaagtgta
     8701 gcgcatacaa gaagaacttt gaagcgcctt gcttgttttt tgagaaagaa atatttttca
     8761 aataaaaaag gggctgtgac aaaaaaatgt cacaacctct aaaagggtct attgaagtag
     8821 aaataacgag ttgtctttat ttcttaattg atcgatattt ttgcccatcc tttgacagct
     8881 tgagcaaaaa taaagattcc tgcaaaagca atgaaggcgc tagtgtcaaa agaaggaaga
     8941 aagaccatca agattgttgc aattatagta ggcaatgaaa ttgaatagat caatgttttt
     9001 aaacaatcaa gaaaagtagc ttttgttagt cgaaagcgtg catagagaaa agcagcaatg
     9061 ttggtaaata gcaaagtgat cagcagattc agaaaactag gataaataga aaatataaat
     9121 gtcaggactt ttatccaaag tggtatagat gcttcactta aaaaagaacg gagctgctta
     9181 cctgttaagt tttttaaaga ttcattggtg tagggaagtt ctaattggtt attgttcaac
     9241 aaagcagaag tcgtgcctgt attaggaaga gctatgataa gtttgttttt taacatcccg
     9301 acactaacaa aattccccat caaatcagta gagatgtcct gttctgttcg ttttccctct
     9361 ggatcaaatg tgaagataat ggagtttgtt tggtaaatga atccttcttt ttcttcggtt
     9421 tgaagctgcc cgttttggat tgtaaaatca ggaatgcgag tagcaatctt ttgcccatcc
     9481 aattgaatgt tgtttaagac ttgaaaaact tgaaaagaga ttggcaaagc cataattata
     9541 ctcaaaacta aaagatagac aatggctttc caaaatggga catttctcgc ctcctttagg
     9601 tctttgaatc gtataaagga actgataatt aattgttttg ttgtcataag tactcctcat
     9661 ctagtagtgt catcacttgc aattctagcg aagtatcaag tgaaatacaa gtgctttaag
     9721 gaaacagctg aatgattggt gaaatatcaa aaaaatgtta ttcttgtcta aagactatcc
     9781 aatataaata aaatggagga aggaatagtg cctacacagc cacagagatc atcaaaaaaa
     9841 ctatttggag tagtggtttt gaatgcggtg atcactttat cagaatttat tggagggatt
     9901 atgtcaggga gtttgtctct tgtttcagat gctttccata accttagtga tacattggca
     9961 attatttttt cttacggggc acaaaaaatg gcccgaaaag aagcaaataa aaaacgtacg
    10021 tatggctacc agcgtttaga aatattgagt gctttcatca actcattcat attgatcata
    10081 ttatccttgt ttttaaccgt tgaagcattc aagcggttca cttcaccaga aaagataaat
    10141 agtcatttga tgctaacagt agcagttatt ggattgctcg cgaatttgtt ctcagtatta
    10201 ttattacgac aagaagcaga tgaaagtttg aatataaaat ctagttattt gcatttgtta
    10261 agtgatacac tgtcttcggt aagtgtgatt atcggagcaa ttttgatccg ttttttcgat
    10321 atctactgga tcgatccagt tattacactg atcatttcga tatatatatt gatagaagcg
    10381 ataatggtga tcaaaaaagc tgccgctatt ttgatacaaa gtgcacctgc tatcgactat
    10441 gaaaaaatgg aacaagaaat tgaagcaatc gatggggtaa aggatgttca tcatgtccat
    10501 atttggcagt atagcgaaaa gataattatt ttcgacggac atattgattt tgaagatcag
    10561 ctactaagcg agattgaaaa gatatatcct cgtataattt ctttattaaa attaaaatat
    10621 ggtattacac atgtgacgat ccaagcagag acaaaggcaa aggatcaaaa aaaattaatt
    10681 tttttaaata aagatgaaag ttattgaaat atagagtatg ataaataaga atttttaata
    10741 aggtaggttg gctcatgaag cagtatcgac agttaaaagg atatttagaa gcaaaaggat
    10801 attgggagat actagtctat ctcttttttg gtggtttggc tacgattgta aattttgtta
    10861 gttttgctct cgcacgccaa tattttgatt taagtatggc cttatccaat tctatttcgt
    10921 ggttttgttc tgtattgttt gcttttgtaa cgaacaaact ttgggtattc cattcaaaat
    10981 caccgaattt tacacatgca cttattgaat gcggtaagtt cttcttctac cgtatccttt
    11041 cttacggatt ggacatgggg gcaatggtat tgttgatcaa tgttatgaac agcaatgagt
    11101 atgtggcgaa aatcatcact caaattattg ttatccttgc gaactatatt ttcagcaagt
    11161 tgtttatttt taaagaaact gaggtttttg aagaagaagt aggtcaaagt gaaaaagacg
    11221 actaggcata acaattgaag aatttccttc tctttgttac tctttgtaat gtagacatta
    11281 ttaagaaaac attgaggagg aattttttta tgacttacac attaccagat ctaccttatg
    11341 catatgacgc attggaacct tatattgacg aagaaacgat gcatctgcat catgataagc
    11401 atcacaatac ttatgtgacg aatttaaatt cagcaattga gaaataccca gaattaggcg
    11461 aaaaaacaat agaagaatta ttatctgata tggacgctat tccaacagat atcaagacag
    11521 ctgtacgtaa caatggtggc ggacatgcta accattcatt tttctgggaa atcatggcac
    11581 caaatgctgg tggcgaacct acaggagaaa taaaagaagc gattaatgaa gcttttggtg
    11641 atttttcttc ttttaaagaa gaattcaaaa aagcagccgc tggacgattt ggttctggat
    11701 gggcttggct tgtaatggaa aatggaaaat tagctattac ctctactgca aatcaagatt
    11761 ctccattgat ggaaggaaag acaccaattc taggtttgga cgtttgggaa catgcttatt
    11821 atttgaaata taaaaatgtc cgaccagatt atattgcagc attctggaat gttattaatt
    11881 gggatgaagt aaacaaacgt ttcgaagcag caaaataacc atttcctccg tcatatcagt
    11941 cttaaaaata atttggaaaa taaaagagcg aaagcttgct agcgttttct aaattgggta
    12001 taatgttctt gcaaggttac ttgcaagaac ttttttggag gatatacatt tatggaacac
    12061 ggaacggtta aatggttcaa caatgaaaaa ggatttgggt ttattacagt agacggcgga
    12121 gatgacgtat ttgttcattt ctcagcaatt caaggagacg gcttcaagag cctagaagaa
    12181 ggtcaagaag tagaattcac gattgttgaa ggtgcacgcg gacctcaagc tgctgaagtg
    12241 actaaattat aataatttgt tgaataaaga cacgacttct tagagagtcg tgtctttttg
    12301 tctatttatg aagtttttag attttttggc taagtaaatg catttgttca cttgacatgt
    12361 cctaactaat tatcaagcaa ggaacatttt cttcgttagt aatggatttt aaagaaattt
    12421 cagtttttgg atgttgaata aaagaccatt tgtgaaacca ctagtataca tactcattac
    12481 catgtcaatt ctattacttt aaaagaaaat cgttttactt tgaagaggag catatctatc
    12541 cattaaaaga tgatggtaat gcaatcacta gttcgagtca ttttaagagc catgcagtga
    12601 gctggaaata aaacgaatag aagatgggtt taacaaaagg accagtcata ggaagaaatt
    12661 gtcgtgaaat cgaatgataa tctgaacggt aggcaaagac tgttaaaaag atgggaaagg
    12721 tatgtgcgat cattttactg cacgattatt tggaaaatac cttgttgttc gctttttctg
    12781 gaaaaaatac ataaaaaaag ataaaacgat tgcgaactgc gtgtattcgg tctttcgatc
    12841 tttttcacgg tatggtatga tagttaagaa ttttgagaaa ttttaaaaaa taataatcgt
    12901 tacacaaaaa tgttttttaa agttttctta tgattaaaaa gtgaatttgc tgattgaaca
    12961 gttatatgag acaatatttt agaaaatgtg aaacagaggt gtattatgaa gcgatggcaa
    13021 aaagttctat taaccttgtt aggggtattc gttttgctga ttgccggatt atcagcatac
    13081 ggaatcagat ttatgggaga agcgagccaa acagtaaaca aaatttctaa aaactctaat
    13141 cgaatatcct ccaaacgttc tgagagagta agcattgatg acaaagaacc tttttcggtt
    13201 ttgctattag gtttagatac cggtggatta ggaagaacgg aacaaggacg ttctgatacg
    13261 atgatggtag taacagttaa tccgaaacaa aaaaaatcaa cgatcatcag tttggaccga
    13321 gatatttata cgaatatcgt aggttatgga acggtagata aattaaatca tgcctacgca
    13381 tttggtggtg tcgaaatggc catggattca attgagcaac tgctcgatat tcctattgat
    13441 cattatgtaa cgatcaattt ggatggcatg gaagatttga tcaatgcggt cggtggcatc
    13501 aaagtgaata ataaaattga ctttactttg gatggtgtcc atgtaccagt aggtgaacaa
    13561 acattgaatg gagaaaaagg tttagcctat tctcgaatgc gacacgaaga tccagaaggc
    13621 gatatcggtc gacaacgtcg tcagcgggaa gtagtgacga aaatcgtcaa taaagtttta
    13681 agtttagatg gcgtaagcaa ttatagaaaa attttaaaag cagttgagaa caatgtgacg
    13741 acggacttag attgggatga catgcttgat gtagcgacga actacacccc ggcgtttgaa
    13801 acaatcaaac aagaccagtt gcaaggcgaa ggacaaatga tcaatgatat ctactatcaa
    13861 attttaggaa aaaatgatct tctttcgatc caaaatgaac tgaagaaaca attaaatata
    13921 aaaacaagcg atacattacc taatttgaaa aatgagaatg cttcaatgat gttctttgat
    13981 gattcggaag atggcgattc gacaaacggt gatggatcga atagtgaagg gtacaccgat
    14041 tattcttcct attcagaaaa cacatatgat cagtaccaag atccgaatac ctattatcag
    14101 caaacagaag atacaagtca gtactataca ccaagtcaag atactcaaag ttatgatcct
    14161 tacgctggac aggaacaaaa tggttatggt tatgaccaga ataatgagta tggaacaaca
    14221 agtgggtact agaaaaaaat agtttggtta ataaagagtg ccacctaaat tagacaaaaa
    14281 atctaactta ggtggcactt tttctatgtg ttaaattaca ggacgtctct ttttagcgct
    14341 tagtttaaaa aataaattga ataattcaat agagttgcga atagtaccca taaataataa
    14401 ggaatcatga gccacattgc caggcgatga tgcagccaca actgatacat aagcactgac
    14461 aagaaaataa ctaaaagtgt aatatcgatt gctgcaatga aaatatttct taaattaaaa
    14521 aatagagcag accatataaa attaaaaatg aactgaatca caaaaagacc gacaagattg
    14581 tttcgctgtt ttttgttgtt gtgattaagt aacaaataaa gagaaatacc catcaatata
    14641 tacagtaagg tccacatcgg cccaaatatc cagctaggtg gtgcaaatgg tggaagttgc
    14701 aaagaatagt aatattttcc gggatttccg ctaagcaacc ctgataaaaa gcctaatatg
    14761 acaattccta taacacaaac ccaaaaacga atatctttta tcatcttcat tttactaact
    14821 cctttctata atattagttt acca
//
LOCUS       DADVXV010000073        14260 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.074, whole genome shotgun sequence.
ACCESSION   DADVXV010000073 DADVXV010000000
VERSION     DADVXV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.074"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(51..3725)
                     /gene="rpoC"
                     /locus_tag="KB969_002162"
     CDS             complement(51..3725)
                     /gene="rpoC"
                     /locus_tag="KB969_002162"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBB6870126.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(3783..7400)
                     /gene="rpoB"
                     /locus_tag="KB969_002163"
     CDS             complement(3783..7400)
                     /gene="rpoB"
                     /locus_tag="KB969_002163"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBB6870127.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8128..9096
                     /locus_tag="KB969_002164"
     CDS             8128..9096
                     /locus_tag="KB969_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6870128.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9114..10019
                     /locus_tag="KB969_002165"
     CDS             9114..10019
                     /locus_tag="KB969_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6870129.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10016..10822
                     /locus_tag="KB969_002166"
     CDS             10016..10822
                     /locus_tag="KB969_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6870130.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10958..11947
                     /locus_tag="KB969_002167"
     CDS             10958..11947
                     /locus_tag="KB969_002167"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBB6870131.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12264..12788)
                     /locus_tag="KB969_002168"
     CDS             complement(12264..12788)
                     /locus_tag="KB969_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBB6870132.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13075..>14260
                     /gene="scm"
                     /locus_tag="KB969_002169"
     CDS             13075..>14260
                     /gene="scm"
                     /locus_tag="KB969_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBB6870133.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SAS"
BASE COUNT         4046 a         3082 c         2813 g         4319 t
ORIGIN      
        1 caaaaaagag gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt
       61 tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca
      121 ttttcgcttg ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta
      181 ccagctggga tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc
      241 ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat
      301 aagaaactat ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt
      361 gcaggaacgc ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct
      421 aataatgtac ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc
      481 atttgacgaa ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa
      541 acacgttgta cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac
      601 aattgttttg gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct
      661 tctgctactt tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct
      721 ttgattgtta cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct
      781 gttacttctg tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca
      841 cgaggaagac cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc
      901 gtcaactgag taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg
      961 acttcaacgt cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt
     1021 tttgtattac atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt
     1081 tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca
     1141 ggatgacgta cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg
     1201 atttcatttc cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct
     1261 tcacggatga ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg
     1321 gcagtcttca aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt
     1381 tccaagacgg atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca
     1441 ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca
     1501 cgagctccag aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt
     1561 ttttgttgga tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg
     1621 tcatctgtga tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca
     1681 ttttcaatga tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata
     1741 ccggcatgtg tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt
     1801 tctgttactt tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg
     1861 aacggtaata ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca
     1921 aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg
     1981 aattcaggag gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt
     2041 tctttttgcc attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt
     2101 gaatgtaaat gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag
     2161 accattcctt cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc
     2221 atatcttggg aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca
     2281 gctaacatca acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc
     2341 atttggtctc catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt
     2401 gcgcgtcctt gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt
     2461 gcccggttca gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg
     2521 tcttcttgac gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga
     2581 acaagctcac gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca
     2641 cattggtaca tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca
     2701 cgtttaccta gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga
     2761 gatttcaatg ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc
     2821 aatgcatcta ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca
     2881 ttcaagtcta acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca
     2941 ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt
     3001 ggaataacag ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat
     3061 gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc
     3121 aattcttctt tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta
     3181 atcgcttctg cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga
     3241 tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact
     3301 acatatgaag caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga
     3361 cccatacgtg aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca
     3421 atatgtccca tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca
     3481 caaacgattc ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt
     3541 gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag
     3601 ttaatcgtct caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa
     3661 gccaaaccta tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat
     3721 ttcatttaat ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg
     3781 gattagtcta aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct
     3841 tccacttgtt cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt
     3901 gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc
     3961 tctgtttctt cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc
     4021 aatacgcgga atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct
     4081 tcgtatgttt tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa
     4141 gtataagccg caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca
     4201 ccaaattgag ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa
     4261 cgtgcatgca atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca
     4321 gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg
     4381 ctggccatac cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat
     4441 actggcgttg ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat
     4501 acttgcccga tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt
     4561 gttccatcag gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta
     4621 tttccgtgac gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa
     4681 acacgaacta acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt
     4741 ttcacatcgt gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact
     4801 tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt
     4861 accccttttg gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata
     4921 cggatgatac ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg
     4981 cgtgtgattt cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata
     5041 tggatagaag tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca
     5101 tagttgtacc cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg
     5161 ccttgttcca tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa
     5221 tgaacgattg gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca
     5281 tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat
     5341 tcaacgacac cgtcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat
     5401 tccataccag taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc
     5461 atgttggcac ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat
     5581 acttctaagt tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct
     5641 tcattcaatg ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag
     5701 tagtcgattt ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg
     5761 ataaatccga atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt
     5821 gggccttcag gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga
     5881 acttcataac cggcgcggtc acgagtcaat ccgccaggtc ctaaggctga aagacgacgt
     5941 ttgtgtgtca attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa
     6001 ccaaagaatt ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc
     6061 aatgtttcag tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc
     6121 ccgatacgga attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag
     6181 tggtcgatat catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa
     6241 gcaatgatgt cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc
     6301 acgtttactt cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt
     6361 ggatctgtga ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca
     6421 atgaaaggag ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg
     6481 atctcgcctg tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt
     6541 ttcaaatcta attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt
     6601 ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct
     6661 ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt
     6721 ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag
     6781 atcgtatcat cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt
     6841 gtacggtcga tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct
     6901 ccacggttag ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca
     6961 tggaaataga cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg
     7021 atgatgaatg ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct
     7081 ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag
     7141 tttgcatcat gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct
     7201 acaaattcca aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt
     7261 tctctaagtc cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt
     7321 ggtaattcca acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat
     7381 tttactacgt gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc
     7441 gatcaattgt tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc
     7501 ggcttttagg caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc
     7561 ttctactttt gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc
     7621 ttcatcagat agtttttgca acttcatata ctacacttat tttctataaa agtcaacact
     7681 tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc
     7741 aattatctga caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc
     7801 attttgtgga ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa
     7861 taacttttac tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta
     7921 aacgacagtt tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag
     7981 acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt
     8041 tttcaattta ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg
     8101 tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct
     8161 gccctgctac tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat
     8221 ggacaaaaaa caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat
     8281 aaaggattca aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc
     8341 gattatcaaa atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc
     8401 aaagaagatc ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat
     8461 gaaacaacca ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta
     8521 gtcacatcca atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc
     8581 gaaaaacaaa tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg
     8641 tataacaacg gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa
     8701 aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg
     8761 acgaaaagtc tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca
     8821 agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc
     8881 gcagttgatc aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg
     8941 ggtaaacaaa cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt
     9001 cctgtcgaaa cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta
     9061 ggcatcaatc cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa
     9121 atttgctctc tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga
     9181 ttggtgtata cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct
     9241 ttcctttagg tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag
     9301 cttgtcttct aggcttttta gggggtgcgg cagcagggct tgtttccgga ctgcttcaca
     9361 caaaattgaa aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg
     9421 tcacatcccg tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc
     9481 attgggtcga gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt
     9541 ttgctttgat cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta
     9601 ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata
     9661 tgaagatcat cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg
     9721 cgcaaaacaa cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg
     9781 cttctattat catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga
     9841 ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg
     9901 ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc
     9961 cgcagatcca gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa
    10021 tgacgtctta acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa
    10081 tcatgtcctg aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg
    10141 tggaaatggg gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga
    10201 tcagggtcaa attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc
    10261 gaaatccatc agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt
    10321 agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt
    10381 caaaccacaa gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga
    10441 aaatcgttta tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt
    10501 attgatggcc acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct
    10561 tgaccctgct acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa
    10621 tctcactgct tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact
    10681 gatcatgctg catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct
    10741 cacagtgccc caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga
    10801 tcaagtactt ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct
    10861 cttctttttt ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga
    10921 aaactatttt gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat
    10981 gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga
    11041 aaagttggca cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt
    11101 ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga
    11161 cgtactagat gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt
    11221 acaaacgatg ttgacttctg aatctacgat gaaagatgtc aaactggcag cagctcaagg
    11281 agattctgtt tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg
    11341 acggcctttt ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga
    11401 caaacggttt gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc
    11461 cattgaatct gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga
    11521 tggaaaaaaa gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat
    11581 cagtcatatc atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc
    11641 tgatctccaa gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa
    11701 tcagctaatc agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc
    11761 gttggacttc tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa
    11821 aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca
    11881 aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac
    11941 gcaataatta tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga
    12001 attctcttca aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa
    12061 aggtattcta aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa
    12121 aacaagagag tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat
    12181 cttatagata gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg
    12241 taagttcttt tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc
    12301 acctgaccag agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg
    12361 actggtggtg tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt
    12421 aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga
    12481 ttagcttgga tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct
    12541 atcgtcatcg gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct
    12601 aaatcagcaa tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat
    12661 ttgatctgcg gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct
    12721 tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa
    12781 taatccattt attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata
    12841 cctacttata tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat
    12901 agtttggaga ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat
    12961 atgaacgttt cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga
    13021 ctaggagaaa aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa
    13081 aaaagggcaa gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg
    13141 gccgtttcag cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact
    13201 ggtaactatg gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca
    13261 actgtgaatg cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat
    13321 tttggtacag agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact
    13381 gattctttcg ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc
    13441 gttggcagta acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg
    13501 cttgatcact taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat
    13561 ttcgagcagg aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca
    13621 gctaaaacat atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact
    13681 gatttatcag ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat
    13741 acgccacttc aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt
    13801 tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca
    13861 gaagattttt cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca
    13921 atcagtgctc cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa
    13981 aaccaagacg gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg
    14041 gatcctaacg aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt
    14101 acagatacat ctaccacaag tgatagctca gattcatcaa cttcaagcga cagtacagat
    14161 actacctcta ccacaagtga tagcacggat acatcagctt caagcgacag tacagatact
    14221 acctctacca caagtgatag cacggacaca tcagcttcaa
//
LOCUS       DADVXV010000074        13902 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.075, whole genome shotgun sequence.
ACCESSION   DADVXV010000074 DADVXV010000000
VERSION     DADVXV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.075"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            71..2236
                     /gene="acm"
                     /locus_tag="KB969_002170"
     CDS             71..2236
                     /gene="acm"
                     /locus_tag="KB969_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBB6870134.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2508..2993)
                     /locus_tag="KB969_002171"
     CDS             complement(2508..2993)
                     /locus_tag="KB969_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBB6870135.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3083..3428
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3473..4114
                     /locus_tag="KB969_002172"
     CDS             3473..4114
                     /locus_tag="KB969_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBB6870136.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4133..4768
                     /locus_tag="KB969_002173"
     CDS             4133..4768
                     /locus_tag="KB969_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBB6870137.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4786..5601
                     /locus_tag="KB969_002174"
     CDS             4786..5601
                     /locus_tag="KB969_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBB6870138.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5920..7356
                     /locus_tag="KB969_002175"
     CDS             5920..7356
                     /locus_tag="KB969_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6870139.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKSSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7545..9977
                     /locus_tag="KB969_002176"
     CDS             7545..9977
                     /locus_tag="KB969_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6870140.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQLSFVPI
                     DSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQDYELPT
                     VDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEVQPAVG
                     VKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIEAQPNH
                     PDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRAKPHEV
                     KLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAATGVRNI
                     SGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMARAAGI
                     HMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLP
                     MGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQPQDELF
                     EEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKVFIEQE
                     ETSETLPDDNDM"
     gene            10207..11274
                     /gene="rlmN"
                     /locus_tag="KB969_002177"
     CDS             10207..11274
                     /gene="rlmN"
                     /locus_tag="KB969_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6870141.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11467..12570)
                     /locus_tag="KB969_002178"
     CDS             complement(11467..12570)
                     /locus_tag="KB969_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6870142.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13122..13670
                     /gene="aac(6')"
                     /locus_tag="KB969_002179"
     CDS             13122..13670
                     /gene="aac(6')"
                     /locus_tag="KB969_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6870143.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         4756 a         2309 c         2944 g         3893 t
ORIGIN      
        1 ttgaagaaag gatttttgag agatgatata gtaggtttta tttttagtta aaatagggga
       61 gatagaaaaa atgaaaaagt gtagaaatat tattttatca atgttattta ttattactaa
      121 tataacatca ctgattcctg ttcatgtcta tgcggatgca ggcagagata tcagcagtaa
      181 tgtcacttcg ttgaccgtgg acccaacgaa tattacagat ggaggaaaca taaaagtaaa
      241 attctcgttt gacgaaaaaa aacaaaatat ccaaccaggt gattatcttt ggatcaattg
      301 gccaagtgaa ggaaatattc gcggtgaagg attccaaaaa gaaatcccat taatgattga
      361 aaataaaaat gttggaactt taacggtcag aaaagattct gcgcaggttg tgtttaatga
      421 aaatattaaa aacctagact cagtagaagg ttgggggcaa tttgagatac aggccagaaa
      481 cgtaaccgat accggtgaag aaaatacggg accattcacc gtgacgagcg gtgataaaac
      541 agctactgta aatgtgacaa agccagcttc tggttcttct tctagcgttt tttattataa
      601 aacaggagac atgctacctg aagatactaa gcacattcga tggtttttga atattaacaa
      661 taacggcact tatgttgaac aaccagttaa aatcagtgat gaaatccaaa gtggacaaag
      721 attagatcca agtacgtttg aaattaatca aatacactta ggtgaacaga aggtttatag
      781 aggagaagag ggaatccaac aatttttaca agatttcccc agcgctacat ttaatttttc
      841 agtaactgat aattacattg aaataactat accaaaaaac tttgtcaatc ttaggaaaat
      901 aatggtgagt tataagacga tcatagaaaa cccagaacaa ataaattttg agaatcattc
      961 ggaagcttgg tttaaagaat ttaataaacc tgctgttgat ggagaaagtt tcaatcatac
     1021 agttaaaaat atttcagctt ctggtggagt caacggtaca gttagaggcg aattgaagat
     1081 tttcaaatat atcaatgaca cagagattgg tatcccaaat gtgactttcg aattaagacg
     1141 agcagatgaa cagcctattc aaggacagtc tagtatcctg ttgacttcga atgaacaggg
     1201 agaagctagt atcaaaggcc tgcaagtagg agactatgtt gtaaaagaaa aagaagcacc
     1261 caattggatt gattttgatc cactaagttc aaatgaactc aaattctcca taaacgaaaa
     1321 tgatacagag ggagtcagtt tacctattta taacaagaaa aaggttacga acatcacagc
     1381 aactaaaatt tggaacggtg gaaccactcc aagaccgagt atttatttta aattattcag
     1441 agcaagtaca aacaattggg aaccagttcc tgatgcagaa acaaaacgat tagacaatgg
     1501 aataacttca gtgacttggg aagatatcca acagtatgat gatagtggaa acgaatatac
     1561 gtttaaagtg caagaagtag atcaaaacgg aaatgattat gtcccttcag gttatcaaaa
     1621 aattgaaaac gggctagtcg ttacaaatga gaataaagaa gtcatttcag tctcaggaca
     1681 aaaaacatgg gaagacaatg agaaccaaga cggcaaacga ccgacgacga tcacagtaaa
     1741 tctattagcc gacggtcaac cgatccaaca caaagaagta agtgaaaaag atgattggcg
     1801 ctatcgtttc acaaatctgc caaaatacag agacgggcaa gaaatcatct atactgtaac
     1861 ggaagacaac gtgcccgaat acagtacgac gattgacggg tataacatca aaaacagtta
     1921 tacaccggaa aaaacaaata tatctatacc aggtagccat ataacaccgt ggaaaaattt
     1981 tccagagaag acagagagag agaaaattag aaatctattc tctcaaaaat tgcaaatatt
     2041 tgctcataca ggagaatcca gcgaacaaag aagcaattat attagtaaga gagctgtacc
     2101 taaacagata acaaataaat caaaaagcat tcttcctaaa acaagtagta aaaaatctag
     2161 ttttgctgta atcattggtt tattgatagt aactatctgt gctgggatat tcttacaaaa
     2221 atataaaaaa gtttagttag aatataatat tttttgttaa atatgactga aatcaaaaga
     2281 ataaaattcc gatttataat cgaaaaaaga agcattttta tatatgcttc ttttttcgta
     2341 gaatcaataa atatggattt ggctaactat ggaagaatac tcgtattagt tttcagcgtt
     2401 catactagtt gttacattgt ttgattggcc aaaagaattt ctgatatatt ttgtgctaaa
     2461 taaagaaaaa gacgcttgaa ttgggaaata agaaaactac tctatcatta caaattttca
     2521 taaactggca gatgttctaa gtaaacaagt atcttttcaa agtcggaaaa atccataatc
     2581 aacgtagtgg tattgatatt tggatgaaag cctacggtat cttgacgatc aatagcagca
     2641 tcgatcacga cttggatttt tttctctttg tcgtgcatca atgctaatgg agtcactgta
     2701 cctgctggaa cgcctaggag gtcaggaagc tgttcttcag aaacaaaaga taagcgcttt
     2761 tcttttaatt gttcagctag ttgttttaaa tcggcgtgct tttcatcagg caagatgaca
     2821 agatagattt gttttccttt tcttgatttc aataatagat tttttacttg cggaccaggt
     2881 agggaaaaag ggacattttt gactgacgta atcgcaggat gatcgacttt ttgaaaagag
     2941 atacccagtt tttttagtag ttcataagct tcttgttcgg ttgcacgact catcgcgcat
     3001 caccctcctt tttttattag tgtatcataa aaaagagttg acaaatgaaa aataatcatg
     3061 taaattacac gtaaagttaa aacaaatgac atcgaaaaga agagtagccg ttaggtgttt
     3121 ttagagagtc tctggttggt ggaaagaggc agcagttaac cgtgaaacac atcttggagt
     3181 cgattttctg aagcgtatag taggaaaatc cggggagccc gttacagctg cggtcgttgc
     3241 tagatgacca gataaggctg gcttttccgt gaggagtcgg taaaaaaagg tggaaccacg
     3301 tgattaacgt cctttgatct tcggatcaaa ggactttttg ttttcatctg aacggcaacg
     3361 actgtgtgag gttttttctg caaggaaaaa ataaacagag gtggaaccac gtataatacg
     3421 tcctcttggc atttgccaag aggatttttt tattttaaag gaggaaaaga agatggagta
     3481 tttgattgaa gttatgccgc aattattagt aggagcactc acaacattga aattattttt
     3541 atttaccttg attggctcat taccattagg gattgtttta gcattaggat tgtctttgca
     3601 ttttaagccg ctacgctact tgcttcaaac atatgtatgg gttatgcggg gaacaccgct
     3661 gttgttgcaa ctgattttta ttttttatgg gttgccgacg attgggatcg tttttgatcg
     3721 tttcgaagca gcactcattg cctttatctt aaactatgca gcttattttg cagagatctt
     3781 tcgtggaggg atacaatcga ttcctcaagg tcaatatgaa gcagcgcaag ttttgcaatt
     3841 aagtcccttt caaacggtga cgaaaatcgt catcccacaa gtgacaaaga ttgttttacc
     3901 ttctgtaggg aatgaagtta tcaacttggt caaagattct tccttgatct atatattagg
     3961 tttaggtgac gtaatgcgtg ctgggaaaat cgcgatggaa cgcgacgcga ctttactgcc
     4021 tttgctaggc gtggcaatca tctatcttac attgactggt attctaacaa tcgtaatgaa
     4081 acaagttgaa ggaaaattaa attattaccg ctaactgata ggaggaagaa atatgattga
     4141 attgaagaaa gtgaacaaag catttggtga aaaaaaaata atcaaagatt tgaatctaat
     4201 cattccagat gggaaaacat tagctatcgt aggtccttcc ggtggcggta aaaccacgct
     4261 tttacgtatc ttggctggct tagaaagttc tgacagcgga gaattttatt tagacggtgt
     4321 accgttcaac ccattcgagc ttaaaatgaa agaacaagtt gtaggagtcg tattccaaga
     4381 cttccagcta tttccacatc tgaatatttt tgaaaacatt accttagcac caaaaatggt
     4441 attgaaacag acaaaagaag aatacaccaa aaaagcagaa gaattagcgg cttcattagg
     4501 gattagtgat ttattgaata tctatcctta tcagctttct ggcggacaaa aacagcgggt
     4561 agcgattgcc agagcattgg ctatgaatcc acgggtattg gcttatgatg aaccaacaag
     4621 tgctttagat cctgaattac gccagcaagt cgagcgtttg atcctatcat tgaaagaaga
     4681 tggggtaacc caaattattg tcacccatga tttagtattt gcagaaaatg tcggtgatca
     4741 attactaaaa gtttccccaa ttcattaaga aaggagaaga tagagatgaa aaaaaccagt
     4801 tttctattcg ctttgatcgc aggtcttctt ctttttgcag gctgttcgaa caaaaaaact
     4861 tcagcagata attgggcgac tatcaacgaa gagaaaaaaa tcgttatagg tttagacgat
     4921 acatttgttc ctatgggatt tagagataaa gacgggaagc tcacaggatt tgatattgat
     4981 ttagccaaag cagtctttga acaatatggg attacggtag actttcagcc cattgactgg
     5041 tcaatgaagg aatttgaact gaacaatgga acgatcgatt tgatatggaa cggctattcc
     5101 aaaacgccgg caagagaaaa gaaagtgcaa tttacaaaac cttatatgga aaacgatcaa
     5161 gtgctgatca cacctaaaga atcaggaatc acaaactttg gacaaatgaa taataagaga
     5221 ttaggtgcgc aaaatgggtc atctggttat gatgtattta cgaaacaacc agaagtatta
     5281 aaagagatag tcaaaaacca agatgctgtt ttgtatgata gttttaatga agcattgatc
     5341 gatctgaaaa gcagacgggt cgatggtctg ctgatggata aagtatacgc agactattat
     5401 ttgaaacaaa gaaacgaact agaagacttc aacataacaa aaggttctta tgagagtgag
     5461 gattttgcag ttggtgcacg caagtcagat agtacattag tgaaaaaaat caatgaagcc
     5521 ctagatcaac tagagaaaac aggtgaattc caaaaaatat ccgataaatg gtttggcgaa
     5581 gatgttacgc cgagaaatta acaaataggg gactgtgaca aaagacgtgt cacagtccct
     5641 ttttccgaat aaacagtgtt ctcctgccaa ctccttgtga ctcggagctg aatggcaggc
     5701 tcacaacctc ttggtaaacg gtgttcaaaa gccagttttt cggtattaag ccaaatttat
     5761 gcaaaaatgt agaaagccat tttcacaaaa tttttcttac tactcgaaac taagcgactt
     5821 tttcacaacc tcctttacat aattttattt tgttgtggaa ggggtttcgt gttattctaa
     5881 aagaggaacg attgaaggtt ataggaaagg aagagatgaa tggaacacaa agaacttacc
     5941 tcatttccaa aagattttct gtggggctct gcttctgcag cgtatcaagt agaaggagct
     6001 tggcaagaag atgggaaagg agaatcagtc tgggatcgat ttgtacggat acctggaaag
     6061 acatttaaag gaacgaacgg tgatttggca gtagaccact atcatcgtta taaagaagat
     6121 attgctttaa tgaaagaaca aggtctgaaa gcttaccgct tctctgtagc ttggacacgg
     6181 atttttccta atggacgagg agaagtcaat caagctgggc tcgcttttta tgagagattg
     6241 atcgacgaat tgattgaaaa cgatattgaa cctatgttga ctttatatca ttgggatctt
     6301 ccacaagcat tgcaagatga atataatggt tgggaatcac gtcagatcat tgaagatttc
     6361 actcattatg cagaaacatt atttgaggca ttccgcggga aagtccatta ctggattagt
     6421 ttgaatgaac aaaatatctt cacttcatta ggttatttgt tagcagcaca tccgccaggt
     6481 gtgacagacc cgaaacgaat gtatgaagtt aaccatattg ctaatttagc aaatgcatct
     6541 gtcatcaata aatttcacga gttagaaatg cctggaaaaa tcggaccaag ctttgcgtat
     6601 acgccaaatt atccaattga cagtaatcct gaaaatgttc tggctgctga aaatgcagaa
     6661 gacctgatgg ccaattattg gatggatgtc tatatgtggg gaaaatatcc gattgctgcc
     6721 atgaggttct tagaagaaaa aggatgggca ccaacgattg aagctggcga tgcagaattg
     6781 ctagaatctg ctaaaccaga ttttcttggg atcaattact atcaaacggc gacgaatgca
     6841 ttcaatccat taaacggagt tggtgctgga aaaatgaata cgacaggaaa aaaaagttca
     6901 tcagaagaaa ctggagttcc tggaatgtat aaaaaagttg agaatccatt tgtcgaacga
     6961 acaaattggg actgggagat tgacccagaa ggattaagga tcggactgcg tcgtatcaca
     7021 agccgttacc gcatgccggt actgattacg gaaaatggct taggagagta tgacaagttg
     7081 acagaagata aacaaatcca tgacgactat cgaatcaatt acttacaaag ccacgtcaaa
     7141 gccatcaaag aagcaatttc ggatggagca gaagtcctag gctattgcac ctggtcttat
     7201 acagatttgc ttagctggct gaacggttat caaaagcgat atggatttgt atatgttgat
     7261 caagacgaaa cacaagaagg atctttggaa cgatataaga aagacagtta ttactggtac
     7321 caaaaactga ttgaagaaaa tggagagaac ctttagttca catacttaaa acaagaaggt
     7381 acggctggat atggccgtgc cttttcttga taaaatcatt tagaaattaa gaaaaactgt
     7441 aaaataagct gaaaaatgaa agaaagcgtc agttctttca aacaaaactt tagttccctt
     7501 actttttttt gtataatgaa acttgatgaa atgagggata ataaatggca caaaagaaac
     7561 ggcctactaa aaaaaggaaa aagacgaaaa aaacgaaaaa gcaaaaacag cagcaggaac
     7621 aaatgctgac gattggtgtt gggtttgcct tgattttatt tgctgtcttc ggctttttaa
     7681 aattaggttt tttaggaata ttgattgcaa acggctttcg gatcattgca ggaaatactt
     7741 accaaatcct ctgtctttta ttagccgtat taggattttg gattgtcatt aagaatacag
     7801 agttttcaat tggtaaaaac cgacgctggt ttggcggcat actcttttat ttcggtatct
     7861 tattattgtt acatgcccat ttatttggca aactccatac tggggaacca aatatcatgg
     7921 ggacgacatg ggatttgtta gccagtgata taaaacaaag tcaagtagac aataacgttg
     7981 gtggtgggat gattggagca atcctttatc attttactta cttcttgatt gcacagcctg
     8041 gaagttattt agcagcagtg ctattactgg caggaggagc attcctgttc agtaatctgg
     8101 aaggctatca gctgttaaat ggtatccaat caattggaga acgagtacag gaattattgg
     8161 aaggtgatcc tgccaagcaa gctcgaaagc aagcggcaaa ggaagagaga atgaaacagc
     8221 gcgcagaagc gaaagaagca aggcgcttag ctgcaaaaga agctgcagaa tatgagaaga
     8281 aaaaagcggt gagccagcaa agggaaaata ctgctgatga atggcaggaa ccagaaaata
     8341 cagagccgga gcagctaagt tttgttccaa tcgacagttt tcaagaaaat atccatcctg
     8401 cgaatctaga gaaaccagta ccagatacac caaaacagac caatacagca gaaggttttt
     8461 cagatgagtt gccagaggat gacggtacct cattagaatt tgagattgaa gcagaacagg
     8521 aaaatcaaga ctatgaatta ccgacagttg atttgcttga ttctatacca actgtggatc
     8581 aaagtgatga gtataaaaaa attgaaaaaa atatcggcgt attagaacaa actttccaaa
     8641 gtttcggtgt cgatgccaag gtcgtcaaag ccagcttagg accatccgtc acaaaattcg
     8701 aagtccagcc ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca gatgatatcg
     8761 cgcttgcttt agcggcgaaa gatgtccgga tggaagcacc gattccaggt aaatcactga
     8821 ttggtattga agtaccaaat ggaaagatca gtatggtttc ctttagagaa atcatcgaag
     8881 cacaaccaaa ccacccagat aaattactag aagtaccttt aggacgtgat gtttctggac
     8941 gggtacaaac ggctgatctt tcgaagatgc ctcacttact cgtggctggt tcgactggta
     9001 gtgggaagtc agtagcaatt aatgggatta tcacaagtat attaatgcgt gctaagcccc
     9061 atgaagtaaa actgatgatg atcgatccga aaatggttga attgaatatg tacaacggca
     9121 tacctcatct gttgacgccg gtcgtgacga accctagaaa agcagcgcaa gccttacaaa
     9181 aagtagtaca agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga gtaagaaata
     9241 tttctggtta caatgaattt gttcaacaga aaaacttgga aaacggaacg aaacatccaa
     9301 ccttaccatt catcgtagtg atcgtagatg aattagctga tttgatgatg gtagccagca
     9361 atgaagttga agatgcgatt attcgtttag cgcaaatggc tcgggcagcg gggattcata
     9421 tgatcctagc tactcaacgt ccaagtgtgg atgttatcac aggaatcatc aaagcaaatg
     9481 taccttccag aatggcattt gcggtatcaa gcggtacaga ttctcggacg atcattgatt
     9541 ctaatggggc agaaaagctc ttagggcgag gagatatgct attcttgcca atgggtgaga
     9601 ataaaccgat ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa cgggtcgttc
     9661 aatttgttac agatcagcaa gaagctcatt atgaagagaa aatgatgccg acagatgaag
     9721 ttgaaacgac aggtgctcca gaacagccac aagatgagct gtttgaagaa gcaaaagcac
     9781 ttgtcgttga aatgcaaacg gcaagtattt cccttctcca aagaagattt cggatcggtt
     9841 acaaccgagc agcacgttta gtagatgaac tggaagctca tggagttgtt ggcccgtcag
     9901 aaggaagcaa gcctcggaaa gtattcattg agcaggaaga aacatcagaa acgttgccgg
     9961 acgataatga catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa ccaataaaaa
    10021 gacaaggcat gatgatacca aaagaaaaaa tggttttttt ccatcttttc taatacggta
    10081 tgatgtcttg tctttttagt ttttgtgaga ttaaagttct attcgattta tttgtgaagt
    10141 attgcattaa ggaaatgaat catgtatagt atgtagcgaa actttgagaa aaagagggaa
    10201 aatactttgg aaaaacagtc catttatggc ttgacgaatg aagaattaat caattggttt
    10261 atagaaaacg gcgagaaaaa attccgagct gcccaagttt gggaatggtt gtatcaaaaa
    10321 cgtgtaagta atttcacaga aatgacgaat ctatcgaaac aattgatcga aaaattatcg
    10381 gagcatttta tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc ggatggtaca
    10441 gtaaaatatt tgtttgaact ccctgataaa aacatgattg agactgtact gatgagacaa
    10501 gaatatggct tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg ctgtacgttt
    10561 tgtgcaagcg ggctgctcaa aaagaaccgt gatctgactg ctggagaaat tgttgcacag
    10621 atcatgatgg tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt ttcacatgtc
    10681 gttgtaatgg ggatcggtga gccatttgat aattacgaca atgtaatgga ctttttgcat
    10741 atcatcaatg atgccaaagg attggcaatt ggtgctcggc acattacagt ttccactagt
    10801 ggattagcac acaaaatcaa ggaattcgct aataacggct tgcaagtcaa tctggctatt
    10861 tccttgcacg cgccgaataa tgaggtgcga acatcgatca tgcggatcaa ccgaagtttc
    10921 ccaattgaga aattgatgga agctgtggat gagtatttag agaaaacaaa ccgtcgaatc
    10981 acgtttgaat atatcatgtt gaatcaagta aatgatagac cagagcatgc gcaacaatta
    11041 gcagatctat taaaagataa gaaaaaatta gcatatgtca acttgattcc atataatcca
    11101 gtcagtgaac atgatcaata ttctcgcagt ccaaaagctg atgtattgag attttatgat
    11161 gtattgaaga aaaacggcgt aaactgtgtg atacgtaaag aacatggtac agatattgat
    11221 gcagcttgcg gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa ataatcgtat
    11281 cctactcgtt ttttcaatta ccataaaagg agcagttttc ttaattaagg aactgttcaa
    11341 cttaaataag agaaaagatt ctatagcgaa agctataaag ctttttttga caagaaaaac
    11401 cctcatcaag caaagaaatg tcctcaattt gatgacagcc tgcttgatgg gggttttagc
    11461 aattatttaa ctgattttct tatatccttg ctggctttct tgtgtagcat gataagtttc
    11521 tacgtcaaga atggcctgtt taaatttttc tcgggtgatt tcataaggca catgtttaat
    11581 atcatttgtt gccatggctt tatctaagat tgcttctaaa tcggtcgtga cattgagatt
    11641 catgtcggtt aacgatactg gaagttggtt ctttttcata aacacataga ttttatcaaa
    11701 caaatcgaac tgctgatcca tcatcaataa ggtcagtaca ccataactga cagatgctcc
    11761 gtgaaggtat ccctccattt tttctagaac agtcgtaccg taatagaatg agtgtgccat
    11821 agcagaatta tagttattgt taactaaaac agaaaccaat ccggtagtaa caatgatatc
    11881 cgaaacgact tgttcaattg catatgaggg acgatcgtcg gcactatctt tcaatgcttg
    11941 cgtaccataa gtcaagagac gatcaatgca catttttccg atttggattc ctaatctatc
    12001 cgtgtagcct agatcatcgc cacgagcaga aaaagtagat tcgacttctt tggataaagc
    12061 atcgccaata cctgcccata agtatttatc aggtgcttcg gcaataattg ctgtatcaat
    12121 gaaggtgtgt acaggtggtt ttgaaggaaa gaagagtccg tccattacgc cttcttcgtt
    12181 atagatgaca cataccgcag tgacgggcga acagttcgaa ccaatagtgg gaaaggtgaa
    12241 gactggttta gctagttttt caccaatgac ttttacagta tcgcaagcac ggccaccacc
    12301 gactgcaaac aggacgtctg ctttttggac actttcatgc tggatcaact gttcaatatt
    12361 tccataagtt gaattacccc cgtaccagag actggcgaca acctctattt cctgtgtcaa
    12421 agctactttt attttgtttt ctgcctttga aagtgcagtc ttccctccaa tcagcactac
    12481 ttttgtccca tattctttga cgattccatt tgctttttca tacgcatctg ttccaatggt
    12541 ataatttggt aagaaaacac tttgactcat attcatttcc ttctttcttc gttgaaacgg
    12601 gttaaaattt taaagagtga tcgatctgac tgcggctgta gatggagtag aggtgaacct
    12661 aagacaggat aagtgatgaa taaggtggca tgaacacctt gaaatcatca ataagtatcc
    12721 taaaaacgaa caagtacaaa aacattgaaa acgacaataa tgaatttttg ttcctcttag
    12781 tatttctacc gattcccttt gcttttttgt aattatctaa aaattctaaa aattaagatt
    12841 attatatgaa aacaggtttt atttgtcaat tcataattgg ttttttttaa agcaaaagat
    12901 aatctatatc atgatgaaca aacagagttt tttcctccaa ttgatggctt tcctgatctt
    12961 tcctattttg aataaagtgt ttctgtataa ttttttattt tataagtaag ataaataatg
    13021 aaagaataga gatactgatt ggtagctaaa gatttttgag cgagaacatt tcgttttttc
    13081 aaaaggactg ttagaataag caagaacaag ggggaagacg tatgataatc agtgaatttg
    13141 accgtaataa tccagtattg aaagatcagc tttctgattt actgagactg acttggccgg
    13201 aagaatatgg agacagctcg gcagaagaag tagaagaaat gatgaatcca gaacgaatcg
    13261 cggtagcagc ggtagaccaa gatgagttag taggatttat tggtgcaatc cctcaatacg
    13321 gtatcacagg ttgggaattg catccattag ttgtagaaag ctcccgacga aagaaccaaa
    13381 taggtactcg attagtcaat tacttagaaa aagaagtagc ttccagagga ggaatcacga
    13441 tttatttagg tacggatgat ttagaccatg gaacaacgtt aagtcaaacg gacctgtatg
    13501 agcatacatt tgataaagtg gcttccatcc agaaccttcg tgaacatccg tatgaattct
    13561 atgaaaaatt aggttataaa atcgtaggtg tcttaccaaa tgcaaatggc tgggacaaac
    13621 cggatatttg gatggcaaaa acgattattc ctcgaccaaa ttctcaataa taaaaagagg
    13681 ttgtgacaga agtaatcagc ttcaagaaat aagaaggaat ttacgaaaat tacttcttga
    13741 atttttgtga aattccaact tatttccgaa gaagctactt ttggaacacc gtgtaccaga
    13801 ggttgtgaaa aagtcgctta gtttcgagta gtaagaaaaa ttttgtgaaa atggctttct
    13861 acatttttgc ataaatttgg cttaataccg agaaactggc tt
//
LOCUS       DADVXV010000075        13657 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.076, whole genome shotgun sequence.
ACCESSION   DADVXV010000075 DADVXV010000000
VERSION     DADVXV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.076"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(275..967)
                     /locus_tag="KB969_002180"
     CDS             complement(275..967)
                     /locus_tag="KB969_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6870144.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1404..1973)
                     /locus_tag="KB969_002181"
     CDS             complement(1404..1973)
                     /locus_tag="KB969_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6870145.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2047..2370)
                     /locus_tag="KB969_002182"
     CDS             complement(2047..2370)
                     /locus_tag="KB969_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870146.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2524..3336)
                     /locus_tag="KB969_002183"
     CDS             complement(2524..3336)
                     /locus_tag="KB969_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870147.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3689..4537
                     /locus_tag="KB969_002184"
     CDS             3689..4537
                     /locus_tag="KB969_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBB6870148.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4682..5623
                     /locus_tag="KB969_002185"
     CDS             4682..5623
                     /locus_tag="KB969_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBB6870149.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5613..7784
                     /locus_tag="KB969_002186"
                     /pseudo
     CDS             5613..7784
                     /locus_tag="KB969_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7896..10067)
                     /gene="copB"
                     /locus_tag="KB969_002187"
     CDS             complement(7896..10067)
                     /gene="copB"
                     /locus_tag="KB969_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBB6870150.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10087..12273)
                     /locus_tag="KB969_002188"
     CDS             complement(10087..12273)
                     /locus_tag="KB969_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBB6870151.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12273..12482)
                     /gene="copZ"
                     /locus_tag="KB969_002189"
     CDS             complement(12273..12482)
                     /gene="copZ"
                     /locus_tag="KB969_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBB6870152.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12495..12935)
                     /locus_tag="KB969_002190"
     CDS             complement(12495..12935)
                     /locus_tag="KB969_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBB6870153.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(13009..13548)
                     /locus_tag="KB969_002191"
     CDS             complement(13009..13548)
                     /locus_tag="KB969_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBB6870154.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3844 a         2847 c         2420 g         4546 t
ORIGIN      
        1 acatttgtat tttatcaaag ttttattata cttgtcaatt tgtgtacatc ctaaaatata
       61 agctatttgt ttacttctgt agaatatata ctttgttgtt agataagttg cacatgttta
      121 tagaatctaa ataataaatt tttatgtacc gcccctcaaa gtgaactgaa ccccaaaagt
      181 tgaactattt aatggactgt ttccgatatt ctactggaga tagtccatta aatagttcaa
      241 cttttggggt tcagttcaaa gaggggggga ttttttatcg ttgtggaata tttaaatacc
      301 aacgcttgtc atgaaaatct tgtgctccac ccttagtatt tccttctgga tcgtttgtcg
      361 cacgcatcat gacgtatact ttcttattag ggaaatcacg catattgaaa gatacatgat
      421 agccaacatt tcctaaagta ttataagctt gatttacgtc tggtctataa atcccatcag
      481 ctcttactct agctagttct tttccagtat tgtagtccat aatgaaaata tactcgtatt
      541 tataattagc aatgtgccat ccagctacat gcaagtttgc gttttcgatt tctccgaact
      601 gatcaatgtg ggcgtaattt gttccatctg tcagcgtaga atttgcagca cctgctcgag
      661 ttggatcaat tactggttta tcctccgaag tagttggatt atcatccgta aaaccatgag
      721 ccaaatcata ggctagtttt tctttactta cacccatttc agaaagataa ccgtaaggat
      781 ctgtatgatc gccccaaata ttttgtgtta cccataaatg cgatttgatt cctggttggt
      841 tataaggagt gtctaatgtt aatggaatac catatttcat tgctgaatct cttgccaatt
      901 caacgtatac tttatagttc ttttcaaaag tttctttatc atgtgtatgt tgtaactcga
      961 tttgcacagg acttttggct cacgaggttg tcctactcta catcttgctg atagatatgc
     1021 tgaaaggaaa acaccaacat tatgttttgc tttttcagct agaacgagac aagcaggaat
     1081 acctttagaa gatatcaaag gttttttagg tcataaagat gtttccacta cacaagtcta
     1141 tgcccatatt tctcccgaag tgaaaaaaag atcaatgaat caactagaaa actatataga
     1201 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
     1261 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
     1321 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
     1381 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
     1441 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
     1501 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
     1561 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
     1621 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
     1681 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
     1741 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
     1801 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
     1861 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
     1921 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
     1981 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
     2041 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     2101 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     2161 atcgatgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     2221 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     2281 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     2341 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaagtgc
     2401 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     2461 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     2521 aagtcattct tggtaaagta cttttgtcag ctttgatttg ctttcgctct caaattcgct
     2581 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     2641 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     2701 tgctagataa tttttttctt ttattggcaa aatctgctcc tctctaaata gcaattcagg
     2761 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     2821 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     2881 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     2941 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     3001 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     3061 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     3121 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgaa tgggacagtc
     3181 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     3241 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     3301 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     3361 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     3421 tatttaaata cgcaaatctt cctcattatt ttttatttta ctcaatttaa tcgtattctc
     3481 atttcaaaac gaatgtactt taaaaaacat aataagatca ctttgcttgt aggatgtatt
     3541 cccttccatt acaatgaaat aaatagcgat tttatgagaa ggtgatgtga aaatggaaga
     3601 aaaaatagaa gaatccaaac aaaaaatcga tcagttgata taagaattag aaaaagcggt
     3661 catcggcaaa cgttcaacta tccaattgat gatcgtggcc ctattagcag gtggtcatgt
     3721 cttattcgaa gatattcccg gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc
     3781 tgtacaggga accttcagca gagtccaatg tactcctgat ctgctgccta gtgatattct
     3841 tggtttttcc gtatacaatt cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt
     3901 taccacgatc ttgttagcag atgagatcaa tcgtacgact cctcgtactc agtcagcact
     3961 tttagaagca atggccgaga atcatgcaac gatcgacaac aatacatacc ctctagacaa
     4021 tcattttttt gtcttagcta cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc
     4081 ggaagcacag ctcgatcgtt ttttattccg actacaaatc ggttatcctt cttttgatga
     4141 cgaacttttg ctacttttgg ataaattcga aaaagtgttg gataacttaa atgaagtatt
     4201 gaacagttat gaaatagaag aaataaaaac aaatgtggcg aatgtctttg tcagtcccga
     4261 agtggcatct tatgccttgc agttagtgtc agcaacaaga agtcatgctg ccatccagct
     4321 tggcatcagt ccacgaggaa gcctttcctt tattcaggca gcaaaagctt atgctttaat
     4381 ccatgggaga aattacgtca cgcccaaaga tttgcaggat ttagttcctt acgtgttttc
     4441 ccatcgcctg attttttacg atcgttcatt gaaggaagac gaaaagaaac aaatcattca
     4501 tactcttgtt gcacaaattc ctattcctgt gaggtagatt gaggtagaca atggaaaaaa
     4561 tcaaagatta tttcattaat tttgtgttat ttctggtata tttcatcatt gtgctttttg
     4621 ctcttgtatt caacaattct ttaggctggt tcttgttggc cttttttact ctttatgtat
     4681 catggagctt gatttcatta agcagctttc taaagaaact ttcggttact tgtacattgc
     4741 agccactcgt ttatcgcaaa aaaagtatgc aggttatttt ttccatagca aaaaagagaa
     4801 ctttttcttt acctctccct cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa
     4861 acaagagatt ttgattctta caaataaacc gcaagaagtc caattgcttt ggcagccaaa
     4921 agaaagagga tgccatgaaa cattaactgt catttttaca gcctatgata gtctaggact
     4981 tttcagaaaa agtgcaaaaa gagagatctc ttttcctgtg actgttctgc ctgctttttg
     5041 taagattcaa gcagaaaaat tacagagagt tctggaaaaa aaacagcagc tgaacgcgta
     5101 ccaaagaggt cttgattttc gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg
     5161 aatcgattgg aaattgtctg ctcatactca agagtggtta taccgtgaat acgattatca
     5221 agaagaagaa tgttctcctc ttttttgctt ttggggttcg cccagtccaa aatttgaacc
     5281 tctgctagac ttgtattttt ctttatggca tttgagaaaa gaaaagcagc cggaacttct
     5341 gatattaggc aaccgcgcct ttcatggcaa agaccccggt catacctatt ttgcttcttt
     5401 ggaagctggc gatgagaaag cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat
     5461 cgtcctcttt gttcctgaga attctcctga agtctcagaa gctattgaaa cattgtcaaa
     5521 agatcgaacg gtttatcttg tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga
     5581 caagatatgt tcattgccag gaggtgaatg gattgacgat taaacgggaa aaatggctgc
     5641 gtggcgttta ctcctttgtg atactaagtg taggtgctcc gatatttgta gtagctaatc
     5701 aattgcaaaa cagctacctt cttatcctaa ctattggtgt cctatgcctt attgtctgct
     5761 gtattcctaa aaaatgggta cgtttgctgc tttctttgcc agtaatgata ggttgtttgt
     5821 ttttatattt tccttcgaag acattttcca tattatggat cttacagttt ttttcgtcag
     5881 tcacagagga attcttccat ctatcccaag gtaaacttta ttatttgcca gaaaagacag
     5941 ctttttttct cataatgttg ctgatctatt tatttattac attgaccgtg gattacgact
     6001 attggtacgc accctttctt tctttgatgg cttacttcat gatgcttacc gtttttcgga
     6061 aaaaagattt actgtacgaa atgattgcgg tagtaactgt tttgttcgtg tatctggcag
     6121 caaggcaatt tttctccatc cggttgttgt cgggaaacac tcgattccag tcattgacta
     6181 cagttctgct tatttgtttc ttaactttta gcgctatctt gcctttatat cttccgaaag
     6241 tacaccaatc tctcgaggaa acgagtgaac cgatccgaga atatcttaat gatgaagggc
     6301 tttatgacac actccatgag tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga
     6361 atgatgaaca gcttggtgga cctttatatg ataatggcga agttgttttt acagcgaacc
     6421 aaaaaggaaa tggctattgg aagatcgaaa ataaaaatca ttacaccggt tctggatgga
     6481 tagaagatca ggacgcaccc atccaaccaa tccaagaatt ccctgttgac atcacgagct
     6541 accaaaccgt tatagaagac aaagaaaaca ttacattgac cctaaaaaaa caagttttct
     6601 taccttatcc ttatggaaat actaccttga ctgatttttc attagctagt ggacaaacgc
     6661 tttactattt gcctgaaagc cagcgattca ttcctgtccc gaatgaatcg acacgttctg
     6721 caactttaca aacagaaagg ttagttttta cgagagaaga attaaaaagc agtcagttaa
     6781 aagctgatga tttagaaaat cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac
     6841 gtattgagga cttggcggtc gaattgacca aaaatgaagc aactttaatt cgtaaagtcg
     6901 aagctgtcta acagtattta aaaacaagcg gaaatttccg ctattccaaa acggataccg
     6961 ggcatactcc aaaagaacac gattatgtgg attatttcct ctttgattca aaagtcggct
     7021 attgtgacaa cttttcaact tctatggtcg tccttcttcg aacacttggt atcccagctc
     7081 gctggacaaa aggttttaca aatgggctca gaacaggcac agataatcaa gggaatgagg
     7141 aatacagcat tctcaatagt catgctcatt cttggccaga ggtatacttt cctggatttg
     7201 gctggcttcc atttgaacca accccttcat ttgccaatcc aatgggttca caaccagttg
     7261 ctgaaacaac cgaaaccgtc cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg
     7321 cagaaactat ttccagtgag agatctgagg tcattccatc agaagaaaca acactcacac
     7381 cagcttataa aatcgtctta ttcagccttg gagtgtgttt atccgtcttg ttgttctttc
     7441 tattgttatt cagaaaatct ctgcgctgga caagttatct tatctatctt catttttttg
     7501 cttctactaa tacgattgca tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc
     7561 gcaaacccgc agaatctttg caggaatata gcctgcgaat agaacaagaa ttcaagctag
     7621 atctgcgttt cattcgatta actactcaat atgaagcaga aatatatgga cgacaagcag
     7681 atccggtaaa attcgataaa aaaacctatt tagaaataac gcatataata agaaaaatgg
     7741 tatacaaaaa aattctgaca aaagggagcc gcttcaaaaa ataagataaa atttctggag
     7801 aatctacttc tggaatgccg agaaccagct gattgagtat cgattactcg aaaaaaaggt
     7861 tgtgacacgt tttttgtcac aacctttttt cattattatc tgattttcaa tgtcaaagca
     7921 tttagagcta caactaccgt acttaacgac atcaagacag caccaactgc tggacttaat
     7981 atgataccaa ttggcgcaag aattccggct gctagcggaa ttgcaagaat attgtaacct
     8041 gccccccacc agaggttctg gatcattttc tttcgcgttt gcttggctag atcaagaaaa
     8101 tgcaaaatat cttttggatc gctgtttgtc aatacgacat ccgcagaatc gattgcgata
     8161 tctgtccctg caccgattgc catcccgatt gaagcacggg ctaaacttgg cgcatcattg
     8221 atcccatcac ccaccatgat tacttttttc ccttggtcaa ggtatttctg gacaacagct
     8281 tctttatcat ctggtaataa accgccataa tattcttcga tccctaaata atctgctact
     8341 gcttgggcag cgtttttatt gtcaccagta agcatgacag gagtgatttt tctttctttc
     8401 aatgttcgga taaattcttt tgcttctgtt tttactacgt cacctaaagc aacgattgca
     8461 gctagatgat tttctaaaat caggaagctg atggtatttc cttgttcttg gtaaggtttc
     8521 aataatgctt gttctacgtt taatccgaga cgctcaactt ctttttcatt aactattttc
     8581 acttgttgtt ttttgactgt tgcctctagc ccgactcctg aaagattttt tagattttca
     8641 gcttgataag gcttgatttc atgttctttc aaataattca taatgccaac agccaatgga
     8701 tgattggcat tcgcttccaa ggctcctaga tattgaagga tttcattttt attgaacgca
     8761 tcatcaagta cttcgacacc cgttacagta aattttcctt ctgttagtgt tcctgttttg
     8821 tccagcatga tcacatctag atcattggct tgctccagtg cattgcggtt tttcaaaagt
     8881 aatccgtttt tagctgctat tgatgtggaa cgagcaacaa ctaatgggat agctaaacct
     8941 agagcatgag gacaggcgat gataaagact gttaccatac gttctaatgc attaggaaga
     9001 tctgtcaaga acaaccaggc gatgaatgcc aggataccca caattaatgc gacataaaac
     9061 agccattttg ccactttgtc agataatgac tctagcttgg atttttctcc ttgtgctttt
     9121 cgcaccattt ccataacctt cgctagataa ccattttcac cagttccagt tacttcgatt
     9181 tcgatcgttc catccccatt gatagaaccg ccaatcactt tgtcattggc ttgttttttg
     9241 attcctcttg attcgccagt cacagctgat tcgtcaacaa ttgtttcacc tttcaagatt
     9301 acaccatctg ttggcatttt atcaccagac cggacgatca aacgatcacc ttcgtttact
     9361 tctttcaatg aaactgtctc ttcttttcca tctttcgtca agcgtttcac tgattctggc
     9421 agtaattctg ctagtttttg taaagcattg ctggcattcg acacagcatt catttcaatc
     9481 cagtgaccta gtagcataat aacgatcaaa gtagccaatt cccagaagaa atccatgacg
     9541 tgtgtatgtg gattgagcag atttgcgata aacgaataga cactataaat atatgcaact
     9601 gtaatcccca tcgcgatcag tgtcatcata gcaggacttt tttgtttcaa ttccatctta
     9661 gctccactta aaaatggctg accgccatag ataaatagta tagttgctaa gatcaatacg
     9721 agccaatcag aaccaggaaa cgttacttga aatggaaatt ccattcccat cattggtgaa
     9781 aaaagaatga ttgggatagc taggataagc gatagccaaa atttttgttt gaaattcccc
     9841 atgtgcatgg aatgatccat gccgccgtgt tcgtgatcca tgtgcatcga atggtccatt
     9901 tgtttgctgt ttgctatatc tccatggtta tgtcccatgt gcatggaatg atccatctga
     9961 ctatggtcat gtttcatctc catctgtttt tcatgagatt ctgtactttc tttgtttact
    10021 acttcttttt tatgctcatg ttttttctcc atatcgttcc cattcatttt tactccatcc
    10081 cttctcttac tttttcatgt gtcgatttaa gcacagggag ttcaacaata cactgacgga
    10141 actaaacgcc atcgctcctc ctgcaatgat tggattcaaa aagcctagtg cggcaaaagg
    10201 aataccaatc gtattataga caaaagccca gaaaagattt tgtttgattt ttctcaatgt
    10261 caacctagac aactcgattg tttgtgcaat ggatgccaaa ctgctattca tcagcgtcac
    10321 atcggctgtt tccatcgcaa tgtccgttcc acttcccatt gccataccga catcagctaa
    10381 tgctaaggcc ggtgcatcat tgattccatc gcctgccata ccgacttttt tgccatcttt
    10441 ctgaagtttt tctacgtagg ctgctttatc ctctggaagt acttcagcaa agatatgctt
    10501 tggatcaata ccaacttgtt taccaatcgt ttcggctgcc agtttgttgt ctcctgtcag
    10561 cataaaaaca tctaatcctt tattctggag ctgcttgatt gcttgtttga cttctagttt
    10621 gatttgatca gccacggcaa tcaacccgat cacttgcttt tcatcagcta aaaacatgac
    10681 tgtttttccc tgctgttcta attctaacgc gtgttcttgg tattcatcaa atgataggtt
    10741 caattcaatt aatcgtttac gtgtacccgc aaaatagcgt actccgttaa tcgtaccgct
    10801 gattccagca cctgggtggg ctgtaaaatc aatcatatcg tatgttgctg cttcttgcag
    10861 ttttccgtat tccacgattg ctttacctag tggatgttca gaagcttgtt ctaaagtata
    10921 aaaaatagat aggacttctt tagaaccgac tagatctgta actttgggct ttccttctgt
    10981 aatcgttcca gttttatcca aaacaatgct gtctaagtga gcagctgctt ctaatgcttc
    11041 tccgccttta attaaaattc catttcgtgc accaacaccc gttcctacca taatagctgt
    11101 tggagtcgct aaacctaatg cacatggaca cgcaatgact aatacagaga cactatggat
    11161 caatgcgagt tgccaatcac cagtgatcaa acctgtagct atgagcgtga taaacgcgat
    11221 gactaatacg atcggaacaa aaatccctga gatccgatct gcgatttttt ggattggggc
    11281 tttgctccct tgagcatctt ccaccatttg aatgatttgc gctaatactg tctgcttgcc
    11341 gacttgtgta acttccatgt gaagtagacc attcgtattg attgtcccgc caaagagcgt
    11401 gtcatccgga ttcttttcta caggaagatt ttcaccagta agcatacttt catctatcgc
    11461 actgcttcct gaaataattc gaccatctgc tggaatctgc tcaccaggac ggatgactag
    11521 ttgatcacca acgactactt cttcaatcgc taacgtttct tctttcccgt ttcttatcac
    11581 ttgggcggtt tttgtttgaa gagacatcaa ttgtttgatt gcattacctg ttttcgtttt
    11641 tgctgtatgt tccaaatatt tgccgagcaa aatcagcgtg atgatcatac tgctgctttc
    11701 aaaataaaga tcttgggggt gtccacggaa aaatccgttg taaatgctca atgcaaaggc
    11761 agccgatgtt ccaattgcta ccaatacatc catatttggt gctttcgtct tgattgcatg
    11821 gtacgcacct ttataaaaac gagcaccgac ataaaattgg acaggagcag acagcactaa
    11881 ctggacgatt ggaaaatgaa aaaagtgaac aatcgccgca tggcttccta acatcatagc
    11941 aatcattgac aacatcaacg gcaaagtcaa aaccgtactc aatataagat cgaatagcat
    12001 ttttttcaaa tacgcttgct tttcttctgc aattttttgt ttgtgggctt catcgtacaa
    12061 aattgcacca tagccgatgt tttctacgct ttggattaat ttttcagtgg tcgtcccttc
    12121 atatttgaca cttgcttttt cagtggccaa gttgactgtg gcattgacca caccaggttg
    12181 tccgttcagc tctttttcga tcctagcaga acaatttgca caagtcatac ctgtaatgac
    12241 gaacgtatcc attttggttt ctgctgttgc catcaaatca cctctgcttt ataacccaat
    12301 ccattgattg cttgacaaat cttttcggat tgaacttttg tttcatcaaa cttgaccgta
    12361 ccgtttgctt ttttcaaatt tactttcact ttttgcacgc cgtcaagtgc gcttactgtt
    12421 tcttctactc ttgctgcaca atgattgcag ctcatacctt cgattgaaaa ttgttgtttc
    12481 attttttctt cctcctattg atgttgttta cattcacatt gacctgggat acagttacat
    12541 tcgatcgtat ctactggttg cttttgttcc agttgtttca aaatctcatt gatatcttct
    12601 tgagtcaaag tggcttcttc tactagatcc gcaatcgtct ctccaatcct ttttgcacag
    12661 atatgggaaa aaagattttc cgtcgcactg cgaactgttt ccatctccga gacagctgga
    12721 taataaatga atttttttcc ttcttgttct gtccagatca cttctttttt taccaaacga
    12781 cccagcaaag ttttgatcgt tgctggtttc caatccatcg aatcagctaa gatctgcgtg
    12841 atttcttggg ctgtcgtctg tccaagtgtc caaataacac gcatgatctc ccactctgaa
    12901 tcactgatct ttactggcgt tttgactttt tccatttatt tcacaccttt cgtttacaaa
    12961 tgtaatcatt atcttatgaa tacagattac acttgtaaac aaaaactgtc aattattttt
    13021 gctctctatt ttcaatttag ttaaaaattc ttgtttctct cgtcttgttt taaggatgat
    13081 cagtttattt cttgcattag ctacttggat cagctgctgt attttcggtt cattgttttc
    13141 ttcaaaatgc cagataaaag ataaaaattc taagtattcc ctgtttagtt tctccgaaaa
    13201 tgattcaggc atatctggcc gagatttttt gtttatcttt ctttttagag aacgccaaac
    13261 tactcggtag atggcgagat aacgcggcac tttaagccaa atgatcttat ctgcttcttt
    13321 aatcctttcc tctaatgtag aagtataatt tccttcaacg atccatgacg gattagatac
    13381 cataaacaat tgctgttctt gcaaaaacca cttttttgcc tgaatactgt agtctgttgt
    13441 atgccataaa aggtctagcg gcagtagcgg aaagtcggtg atttctttga tcttccttgc
    13501 gagggtcgat tttcccgacc cactttgtcc aatcacgatg atcttcattc ttctccctca
    13561 cttctctttg gaatttggtt cgatcatacc acttataacg ccgcaaaaaa acaagggact
    13621 gtgacaaaag tcgtgtcaaa gtcccttgtt tcgaata
//
LOCUS       DADVXV010000076        13328 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.077, whole genome shotgun sequence.
ACCESSION   DADVXV010000076 DADVXV010000000
VERSION     DADVXV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.077"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            14..145
                     /locus_tag="KB969_002192"
     CDS             14..145
                     /locus_tag="KB969_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBB6870155.1"
                     /translation="MATAAAVAGLVASVKKTVIDPIDEKEAMIEENRKKAMRKRVSR"
     gene            complement(207..2018)
                     /locus_tag="KB969_002193"
     CDS             complement(207..2018)
                     /locus_tag="KB969_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBB6870156.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(2015..2380)
                     /locus_tag="KB969_002194"
     CDS             complement(2015..2380)
                     /locus_tag="KB969_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBB6870157.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(2543..2938)
                     /locus_tag="KB969_002195"
     CDS             complement(2543..2938)
                     /locus_tag="KB969_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBB6870158.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(2956..3918)
                     /locus_tag="KB969_002196"
     CDS             complement(2956..3918)
                     /locus_tag="KB969_002196"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBB6870159.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(3918..4130)
                     /locus_tag="KB969_002197"
     CDS             complement(3918..4130)
                     /locus_tag="KB969_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBB6870160.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(4151..4849)
                     /locus_tag="KB969_002198"
     CDS             complement(4151..4849)
                     /locus_tag="KB969_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBB6870161.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(4869..5411)
                     /locus_tag="KB969_002199"
     CDS             complement(4869..5411)
                     /locus_tag="KB969_002199"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBB6870162.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(5543..6547)
                     /locus_tag="KB969_002200"
     CDS             complement(5543..6547)
                     /locus_tag="KB969_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6870163.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(6544..7533)
                     /locus_tag="KB969_002201"
     CDS             complement(6544..7533)
                     /locus_tag="KB969_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBB6870164.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(7530..8336)
                     /locus_tag="KB969_002202"
     CDS             complement(7530..8336)
                     /locus_tag="KB969_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870165.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8502..9458
                     /locus_tag="KB969_002203"
     CDS             8502..9458
                     /locus_tag="KB969_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6870166.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(9535..10053)
                     /locus_tag="KB969_002204"
     CDS             complement(9535..10053)
                     /locus_tag="KB969_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6870167.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(10141..10290)
                     /gene="rpmG"
                     /locus_tag="KB969_002205"
     CDS             complement(10141..10290)
                     /gene="rpmG"
                     /locus_tag="KB969_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6870168.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            10518..10964
                     /locus_tag="KB969_002206"
     CDS             10518..10964
                     /locus_tag="KB969_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBB6870169.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(11159..13054)
                     /gene="asnB"
                     /locus_tag="KB969_002207"
     CDS             complement(11159..13054)
                     /gene="asnB"
                     /locus_tag="KB969_002207"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBB6870170.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         4147 a         2830 c         2273 g         4078 t
ORIGIN      
        1 attagtagga agtctggcaa cagccgctgc cgttgctggt ttggttgctt ctgtgaaaaa
       61 aacagtgatc gatccaattg acgaaaaaga agcaatgatc gaagaaaacc gtaaaaaagc
      121 aatgcgtaaa cgcgtttctc gttaataatt atttaaaaat acgcatgaag actttctaaa
      181 aaacagataa gtcatcatgc gtatttttat ttgtcagtca atataagttg tgctatttta
      241 tctgcctgtc tcagattcca tggatctgta taaggtctag ctactgctgc agttagccaa
      301 tccacacctt caacaggtat tccatagcaa taaaagtcag actggatttc ccctgaagca
      361 tcaatcacgc gattcgtacc tcgctcaaca tctatagctt ctgaatgata acttcctgta
      421 ttatctgaaa atgaaaaagg gcgaacaagt ttgttttcct tcaaattttt tatgacagga
      481 ttacttgaac gagaaaagct tgtttgtggc aatcgagctt caatcaaata gcgactgctg
      541 atttctttat cttgtagaga aataacatag cggttgtgct tttgctgaat atcaaatggc
      601 ggttcgatca aatgaaaaat acccgcatct atcagtgctg ctaattcttt cgtccgaatg
      661 attggcggac cgatcgttaa aaagctattt agatgagtaa accatcccca tagtatttct
      721 ttgtattcct tagcagaaaa aacgtgccat tcaatagcct gccggattgg atcacgccag
      781 tcttttaatg catcaaatgt tgaagcaaat gctcctgtgc aattgccttt ttccgcttct
      841 tttatctgcc cttcaataaa tattcggcta gcttctgaaa agggctcatt ctgataggca
      901 agaggagttt ctaaatacga ccaatcccat ctataaggga ttagtgctgg atgctttccg
      961 agacactcct ctgaagagag ggagagaaaa tcatgctcaa aatttttctt tggaatcggc
     1021 aagtgatatt cttcgatgat tttcttgtaa taaaacaact caacgtcttt tttcagatag
     1081 tcaaaaaatg tttcgccagt caaaaatccc gactgatgcc attgctccag gttttctttt
     1141 gttagtaacc gtggccatgc cattgctccg ccttgctttt gatttcttcc tcgagggtaa
     1201 taagggagcc cccttcttga tccactgtat acaatcggtt ccttgcctga tggatgatag
     1261 accagttttc ccttttcgtt ctcgaagcgc cctcctcttg atactgtaaa caatccgaca
     1321 taatcaaaaa aacttaagcc tagacctctt aaaaagacat tttctttagg cggtatcttc
     1381 gaaagatcta catctgcagg attagaagga agctgataca gtaaaacatt tttctttgcg
     1441 tagtctaccc acactctttc ttcttctgtc tcatcatttt cccagtgacc gcttgctaaa
     1501 acaagctgat cgatagaata gctttgctga tctgtctgta aaagataacc atcttttctt
     1561 ttgcttactt tttttactaa agaataaaca aactgaatag aagctggaaa ttcttcttgc
     1621 aactttgaga aaaaccagcg ttgatagagt ccgtataaac atcgagtaga ttgctgatct
     1681 ttttccagac gattgatttc ttctataatt agttgcttat ttttggttac cgtctgttcg
     1741 atataatctg tagcaggtcc tttactccat tgaaacaagt tgggtccctg tgttaccaat
     1801 cctccactgg acaatgtttc atctgtaaaa agcgtcactt gttgagaaac agaattcatt
     1861 aataactccg gtggctgatt caaccgccaa actcgacctc caggaccatt gggatcgaaa
     1921 agaaaaagtt caagagaatg tctgtcctga ttattatgga gaatcctttc tgctacactt
     1981 aatcctctag gtccggcacc aatgatccct attttcattt gcatgcctcc atttcgataa
     2041 attttttcaa taaaacagca tggttctgat gttcattttt tgcaccataa acaaaagtaa
     2101 tgactggatg ttctttcata agttgactga gtttaaaaat agcttgcttc ttttcttctt
     2161 cgaaaatcaa ttcttgctgg tatttctttg caaatgaagc aaatcgttct ggtacatggt
     2221 caaaagtttt gcgtgcttca ttactaggtg caatttcttt caaccacaga tctaactgcg
     2281 ctttttcttt tgaaattcct cgtggccaga atctatccac gagtattcta tagccatcct
     2341 ctttttcagc atcaaggtaa acacgtttta atttgatcat agttgtttcc ttctttctac
     2401 cttttcgctt agcttatata tgtagataat agcacaaaat aaaaaaaatg aacggcacaa
     2461 ctatccattg cgccgttcat gtgatcttgg tcaaaatcta atgattgatt cggtttttaa
     2521 agctgtcata caatcatctg ttttatactt ttttactttt gatttttcca gaccatccgt
     2581 catatccacc cttaagtaaa taaatctctt gataacctgc tttacgtaat ttatttgctg
     2641 tacggatgct caaacttttc ttttgatcgt aaatatagac aggctggtct tttcgaatag
     2701 atcctaatga atctttcaaa acagtgtaag ggatgtttct tgcacctaaa atatgcccag
     2761 catcaaacac atctttttcg cgaacatcga ttacttgtgc ttttctcatt ccttctcgaa
     2821 attcttcttc tgtcaaagtc gttgctgaac gtttggccat tactcgtaga tagacttccc
     2881 aaaggatgat tgcaagcaca atcaatagca aaatgatatt aattacccat aaaaccatgt
     2941 aatgcctccg tttttttaag caaatttcaa ggctaatgag gcagcaccaa tgacaccagc
     3001 ttcattacca agctctgcta atttgatttt tgttgattct cttacttgcg ggaaagtaaa
     3061 ttctttaaaa tatttctcta cacggctacg taaaaattct cctgctgccg atactcctcc
     3121 acctaacacg atacttgacg gatttaatgt attccccaag tttccgcaag ctaaacctaa
     3181 gtagaagcat acgcgatcaa caaccatcaa tgcaaacgga tcgtcttctt gagccatttc
     3241 aaagatatct ttacttgtta cttcttctcc gttgtctagc attgctttca gttttgaatc
     3301 ccctgcgtat tcttctgcca agaaacgacc taggcgtacc acacctgtag cgctagatac
     3361 agtttctaaa catccgcgtt taccgcaagt acattcgaac ccttcaggat ccacagtgat
     3421 atgtccgatt tctcctccag ctccgctcac gccgtgaatc aaatttccgc cagcaacgat
     3481 acctccgcca acacctgttc ctagagtaac gaatacaacg tctggatcgt tttctccagc
     3541 acctttccat cgttcaccta aagcagcaac attcgcgtca ttatcgatag cgaatttgat
     3601 tcctgttcct gcctcgatca gttttttcac aaattgaact tctgtccagt ttaagttata
     3661 cgcaccaata accgttccag cttcgctgtc cacgcttcct ggggtaccca tgccgattcc
     3721 gataaagtct tcggctttca tattatataa attcaaacga tgattgattg attcaatgat
     3781 ttcaggaacg atatgcttac catcatccaa aatattggta tcgatgctcc atttttgctg
     3841 aatctctcct tctggtgtta aaattgcaaa ttttgctgtt gttccaccta aatcaatccc
     3901 aataatcttc ttgtccatta caaatttcct ttctttcggc tttcttcaat tcggtgctct
     3961 ctttttaata tgcgccacgc tgtcatgtat gtatcatgat caatcaaacg gctatcatac
     4021 agattacgca attcgatagt cattaattca atgtcataga tgcgtgcacc cacatagata
     4081 aagatgccaa attttttgaa cagctgctgt acatcatata agctctccat ctttaagcac
     4141 ttccttcata ttatacaagt aaaccatatt tttttaaacc cagtaaaata catattacaa
     4201 aaagaaatac aaaaactagt gtagaaagaa tcctttggtg tatcgaatag cttgtctgtt
     4261 gtttcggtag acccaaaaca ttccctaaca ctaatccgcc aattagccca ccgacatgtc
     4321 cccaaacatc tacagaggta tccagaagac caaaaacaaa tgtcaacaca ataaataaaa
     4381 gaaaatgtct gactagctgc tggatcgctg ggttatgttt aaaatgaaac cctaagataa
     4441 acaacgcacc gaacaaaccg aatatcgaag tacttgcacc accagacaga acattcgctt
     4501 cgttaaaagc aaagcttgct gtatttccca ttatcccgct gaacatataa atcaagaaaa
     4561 aacgccaatg gccatagatt gcctcgattt gctgccccat aaaatacagt atcagtgagt
     4621 tcattacgaa atgcatcagt ccaaaatgga tgaagattgg tgtcactaaa cgccaccatt
     4681 cattgaagtg aacaagataa ggaccataca ttccggcata ataagggatc tcaagtcgcg
     4741 gaaataattc catcatgagg aagaccgctg tctgtatccc taaaaaagca taggtccata
     4801 acggtcgtct taaccatgca cgcaatttta tttgctgttg ataattcatg aaaacctccc
     4861 atttcatttt agtcaataaa caattgttgg atcttctgat caaagctctc cggttgccat
     4921 tgttcattca attgttcacg aaaaacaagg ctacatgttt ttttatgaaa attatttaaa
     4981 taccggtcgt aataaccacc gccaaaaccg attcgataac cggctctatt gtagataata
     5041 cctggtacaa tgaggagatc gatcatctcc ggcaaataga gcttctctga ttgtggctca
     5101 agaacaccaa aactcgaacg tacaagaacg gactgttcat ccatttcata aaacgccatc
     5161 tgacgtttcg gcaaagtttt aggtacaact attttctttt gttctttttc tgctcgttgg
     5221 ataaccggct gtgtatccag ttcaaattca ttcgataaag tcgtccctat cacttttgct
     5281 gacttccagt actcgctggc gaatagctgt ttatagattc gctgttcttt ttcctttttc
     5341 ttgccacttt tggccagatt tttcagcttt tcgattcctt tccggcgtaa tcttactttc
     5401 aattggtcca aaaactcacc cttccttctc tcataaaatg gtataggaaa aaaagaaaaa
     5461 tagcaatcga actttcaaat aaatgcataa atagaataaa aagaagacct agaaatgatt
     5521 ggccttcctt ttttaatgaa tttcaactgt tcagcgcgtg tttttgtctg ataaaaagtg
     5581 catacagaaa atatggcgca ccaaaaaggg caatcaaaat tcctgtaggt acttccccac
     5641 ttggtagaat cactctagca accatatctg cactaagcag aaaaatggaa ccgaacaaac
     5701 cgctcagaac aaaggtccag ttattttctt tacgtacgac tagcttcgca gcatgaggag
     5761 ctagtagtcc tacaaaagat aaactacctg tcaccgctac actaccgctt gccaaagcaa
     5821 cagctaacaa caaaaggatt ttttgacttt tagccacgtt aaggcctaat ccttgcgcgc
     5881 gttcttgacc aaatgatagc aatacaatcc tctgtgcata aagtcctcct agcggaatta
     5941 agataaccgc ccatggaagc aatgcccaaa cataaggcca gctcgcaccc cagattgatc
     6001 ccgctaacca tgcattcaca aatccataat tttccttaga taattggatc gtgcatagca
     6061 atgttaatgc agaaaggccg gcattaacgg caataccgga caataagatt cgattcatac
     6121 ccaaaaagcc atttcgatca taggccgcaa gatagacaca gcaagcagct aaaacaccac
     6181 ctagaaaggc tacaactagc aatagaaacg gcagcgaata gtgcgaaaag aaacctaaat
     6241 aaagcatcac taaaaatcct gctccggcat taatgcccaa tatactagaa tctgccaatt
     6301 catttcttgt tactccttgc aagatataac cagaaacgcc aagacaagct cctgctaata
     6361 aactgatcag taatcgagga actcgaaatt ctctaacaat cagcgccaaa gaagatgatt
     6421 ctttccctat gaacgtggca aaaagctgat ccaggtaaat aaaaggcgta ccaatcatta
     6481 aactacctat agacaggatg acaagtacaa aaagcaagaa atagaacgtc caatatattt
     6541 ttttcaccgt tgttccctcc ttacttgtat cagtaaaaac ggaacgccaa tcaatgcaat
     6601 gactaatcca aaaggtgttt caaaaggggg attgatcatc ctcgctgtaa aatccgccaa
     6661 cataaccaat ccaccgccaa ctaaaaaaga gacaggtaga acataacgat agtccgttcc
     6721 aaccattccg cgaacaactg gcggaaccaa cagcccaata aatgaaacag gtccgactaa
     6781 cgaaacggca atggctgcta acactgcaac tagacagaaa acaatcaacc gcgttcgttt
     6841 aggatgactt ccaagagcta atgcatgtgt ttcactcaaa tgaatcaaag atattgcttt
     6901 tcctaatgaa aaagaaacca aaacagcaag tatatataaa ggaaacaata ctgctaattg
     6961 tttccatgtg atattggcag ctccgcctac aaaccaaaaa gcaagatcct gctgcagatt
     7021 aaagaattgg gtaagtgctt ggctgatagc agtaaaaaaa gaactaatag ctacgccagc
     7081 taaaatcagc tgtaaaggat tcatgcccat tttcgaaaac tgcaaaaaac caaatacgag
     7141 caaagttaca gcaaaagaac ctgccaatga cattagaaac acagaaaaat cagaagcttt
     7201 aggccaaaaa gcaaaactaa gggccattgc caacgaagca cccgcgttga ttcctagtaa
     7261 gcctgaatct gctaaaggat ttcttgtcac tccttgcatc aatgcaccgc tcaatgcaaa
     7321 acaactccct acaagaaatg ctcccgccac acgaggcaaa cgaatatttc gtatgatttg
     7381 gtgactttgt tttgatctat caaaatcaaa caacgcctgc caaaaatctg ctttttccac
     7441 agtcgctgcg ccatttgaaa gagcaacaaa aaaaataatc aaaagaacaa aacagaccaa
     7501 aagcaggagt ctatttttct tcatagtcct cataattgat cctcctgctc ttttggcaac
     7561 aaatcatagg ttagaaaaac tggtttattt gttcttggaa gcgtgacaat cgttgcatca
     7621 atctcaaata tttttttcat acactctttt gtgatcactt cttcaggtgt accttctgtg
     7681 atcaacttac cgtttttcat tgctaataaa taatctgaaa aacgtgaagc atgattaatg
     7741 tcatgaatcg acatcaagat cgttgtttgt ttcatttgat tgatttcagt caataactgt
     7801 aggatctcta attggtgtgc cggatctaaa aatgttgtcg gttcatccaa gatcaagata
     7861 tctgtttcct gagcaagcgc catagcgatc cagacacgct gggtttgtcc accagacagc
     7921 gttgcgatat cccgcatacg aaatccagct agacctgtag catccaacgc ccactcaatt
     7981 gcttcatgat cttgcgtgtc catgccactg aacagttttt gataagggta tcgtccgtaa
     8041 gatactactt cttctactgt catacctgta gggtgttcac tagtttgtgc taataatgca
     8101 attttttttg caagttcttt tgaactgtat gtagagatat cagagttatt gacaatgatc
     8161 tttcctgatt tcacaggtag tatacgggta aaacttttca ataaagtaga ttttccactt
     8221 ccatttggcc caatcaaact agtgattttc ccttcaggaa tcgtaacaga catgttttca
     8281 atgatttttt tgttttcgta gccggctgca atgtcagctg ctcttaatct cgtcatttca
     8341 cccatccttt cgctgaaaat cattctcaat tatgacgctg tttcaacatt tcgtcaagcg
     8401 ctactttcat atctatagcc aaatgaagcg gttgacagcg ttcgaaatat caggaataat
     8461 aaccaatgag aaagattctc aattatgtta ggaggaaaga aatgaaatta aaaacaaaag
     8521 tattcacatt atctagcata ttgctgctgg ctggagtact gagcgcttgc tccccctctt
     8581 cagataaaga aacagctaca actgccaatt cgacgacttc atccaatagt actcatacag
     8641 tcacagatac acttggacat aaagtagaga ttccaaacgc gcccaaacgg atcatcggca
     8701 gttacttaga agactatctg attgcactag gggaaaaacc tatcgcccag tggactgttg
     8761 gcagtggttc cattcaagat tatctgcaag atgatttaaa ggatgtccca acgatttctt
     8821 atgaccttcc ttatgagaaa gtgttaagct ttgagcctga tttgctgttg atttcttctt
     8881 ccgctactgt cgaaggcggg aaatacgaac aatatagcaa aatcgcgcca acttatgttg
     8941 taaaaaacgg aacagatgtc acatgggaag aacaactaaa agatgtcggc aaagctttgg
     9001 caaaagaaaa agaggcagaa aaaatcattt ccgattatca aaaatccatc aagaaaactc
     9061 gagaagaact agcagataaa atcgagaaca agacagctgc agtgttgtgg gtgaccaaca
     9121 actcagcctt tatggtcagc aaaaatcggt caagtggaag aatcgtatac gacgatctgg
     9181 aatttggtgt tcctgatcta gtggaagagg tctccaaaaa agccacttct gactggtctg
     9241 ctgtttcctc tgaaaagcta gctgaattag atgctgacta catcatcctt gtgaacagtg
     9301 acaaagatgc tgccatgttc aatgaaccaa gctggaagaa tctaaaagca gtgacagaca
     9361 atcatgtact gcaattcgga cctgaatcta gttggctata taacggacct attgccagtc
     9421 aggaaatggt caatgatatc aaagaaaaac taaattgatt ttaactaaaa aaagcatctt
     9481 cacgattagt cgtgagatgc tttttttctt attaacaaac tagacgcata gattttattc
     9541 ttcttttgaa gcaaccctat tttttactct ttcccatttt tgaaaacgat gggcatatag
     9601 attttcttga tccgttatcc cctcatactc ctctataagg gcgaagtctg aaaaatcaat
     9661 attcccaata tacgtatcgc cttcaaacgt gctatcgatc aatgttcgcc agatccgacc
     9721 agtgtaagga agaagttctt gaaaaatccg actaccaccc gaaacataga tatcttctga
     9781 gatcgtttga ctatacgaca aaagttcatc gatcgaatgc attacttccg cattttcttt
     9841 cgtgcgaaaa tttggttgcg ttgtcaacac gatgatatgg cgataaggaa gtgaaagatc
     9901 ccccattcct tcataggtct ttcttcccat cactaaaatt cgatccattg tatgttcgcg
     9961 aaagaaacgc atatcatttg gcaatcgcca tggtaacaaa ccatttttgc cgatcagacc
    10021 atttttatct tgtgcccaca tggaaataaa catattatcc gctccttatg attttagatg
    10081 ttttgagata aaaaaagtct caattctttg accagcaagg aattgagaac tttaaaaaca
    10141 ttattttgtt tcacggtgca aagtaacttt gcgttcgcgt gggcaatatt tttgtttttc
    10201 caaacgatca ggattgttac gtttgttttt gcttgttaga tagttacgtt ctttacaaga
    10261 agtacactct aaagtgatgt ttacgcgcat gtttttccct cccattttta caagaatcct
    10321 ctaagatgac tctcagactt gattatctta ccatgatttt ttctagattg ctagtgtttt
    10381 tcacgatttt gttaagtaaa actacttgac gataaataca acggttttac ttctcaaaca
    10441 aaatcttttt ctttttgtat aaataccctt acacttgttt atatagatta tgttttttaa
    10501 taaaggggga tactaatatg ccatggaaca tgaaggactt tcctgcatca atgaaaaact
    10561 tagataaatt gacaagaaaa aaagcaatcg acatcgcaaa tgcattatta gatgaagggt
    10621 accctgataa ccgtgcgatc ccaattgcca ttgatcaagc aaaaaaatgg tatgaagatg
    10681 ctagtgaatc agaaaaacga actttcgaaa aagaaaaaaa tccaagcaag acggatgaac
    10741 acgatacgaa tcctcgtgct ggaaaactgc ttgattcaga tgtgatcgta gaatatgagg
    10801 aagaacaatg gatcgtgaaa tctaaagggg caaaaaaggc aagcaaccat tttgatacaa
    10861 aaaaagaagc aatcgaaaaa ggaaagcaag tagcacaaaa caaagaatca actttgttca
    10921 tttataaaaa agatgggaca aaagaaaaag aaatcgatta ttgaacatat gtaaaggggt
    10981 tgtgacgaaa atcgtgtcac aaccccctta tgttcgaaac aatggtgttc ctctgccaac
    11041 tccgaaccat aagtcataat atctataaaa cgggaagagc tgttttttga aattgtttct
    11101 tatcactcag tgttaaacgg taggagaaaa cctctttttt attgatattt gattttcatc
    11161 aaacagtcac atagtcgatt gcttctgctt gcggaatcgt ttcatctaca aagtagactt
    11221 tataccatgt caagaaactg aagattgtcc agatttttct ttgctcttct ttacgtcctt
    11281 cgtgatggtc atctagcaac ttcatgattt tttcttgatc aaaaaattct tttgcaaaat
    11341 ctgcttcgaa taatgctttg acttgttcgt agccgtgttc ttctttcaac caagctttga
    11401 ttggcacagg gaatcctaat ttcacacgat tcgaccattc ttccggaaga tgtttgttcg
    11461 cagcttgtct gaaaatatct tttgtgttgt tttgattcaa taaaaactta cttggtattt
    11521 gttgagccaa tttcatgact tcgatatcca ataaaggtac tcggacttcc aaagaacttg
    11581 ccatagaaag tttatctgcc tttaacaaga tatcttttgg catccattga tgaagatcga
    11641 catattgcat cttattgact tcatctttga ttccttctgt tttctcgtaa tgaacagtca
    11701 tgatttcatc cacagatggt gctgtttgat attttggtgt taacacttct gatgcttctg
    11761 attcttcgaa cactcgagca tgaccgataa aatattcttt tgcaggagca agtgattcat
    11821 ataaatggat ccgtccatgg aagtttttca tttttccgat tttacgtcct aaattatagc
    11881 gtgttccttt tggtaatttt ttcaatcctt gagcaatcac acggatgaat tttgaattcg
    11941 tatggaatcc atacgtttgg tatcccgcaa acagttcatc cgccccttct ccagattgga
    12001 ctacccgcac actttgtgaa gcaagatttg ctaaaaagta caaaggtacg caagaaggat
    12061 ttgaatcagg ttcatctaag tgatactgga tcaaagggaa tgctttgaac gacatgtctc
    12121 cgtcgatcac tgctgctgta ttatctaagt ccaatagttc ggttagtttt ctggcttcaa
    12181 tcgcttcatt ataggtttta tcatcaaacc cgattgagaa agaatgatct ggtttcaata
    12241 cagaggttac ataactggaa tcaaccccgc tggataagaa agaaccaact tctacatcac
    12301 tgaccgtatg tgcttcaata gaagcttgaa cggtttcgtc gattttttcg atccattctt
    12361 gtcgggaatg cgtttctttt gtttcaaaat ctgcatccca atattgctga atgtctattt
    12421 ttccatcttt atacgtataa taatggcctt caggcaaacg atagacatct ttgaagaatg
    12481 tttcgccgtt taatggagaa tattggaaag tcatataagg tttcaacgct tctttgttca
    12541 attctttgtt aaaatcagga tgaggcagaa aacttttgat ttctgaacca aacataaatg
    12601 ttccgttcat ttctgcataa taatatggtt tgatcccaaa gtggtctctt gcaccgaata
    12661 actcattctt ttcattatcc caaatagcaa aagcaaacat tccgcggatc ttttgcaata
    12721 attctgttcc ccattcttcg taaccatgca aaaggacttc tgtatctgca tgtgtttgaa
    12781 aaacgtggcc agctgcaatc aattcttctc tcaaaggctg gtaattatag atttcgccat
    12841 taaaaataat gatctttgtc cgatcttcat tgtaaatagg ctgagtaccg ccctctaagt
    12901 caataatact taatcttctg aatcctaaag caacatgttt atcgatatat tctcctgaac
    12961 tattaggtcc acggtgaacg attcgatcca tcattgtatt aataattgtt tttttgttgt
    13021 ccttgtcgtt aacaaaacct acaataccgc acatttaact ttcacatcct aatataaaat
    13081 tactgtttat ttcattcata tgcatcttat catagaataa atagcggacg aatattttct
    13141 ctcttacaat ttcgtcacgt gaaaacaaaa gatgaaagtt tctgttttta cagaaaataa
    13201 agtcccaata tctaatttac catgttttct tttttgaggc taccttattc tcttcgtgtt
    13261 aaaaaaatat tagtggatgc tatttccaaa aaaaccagca aaaaaagaca cgacctaaag
    13321 atcgtgtc
//
LOCUS       DADVXV010000077        13027 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.078, whole genome shotgun sequence.
ACCESSION   DADVXV010000077 DADVXV010000000
VERSION     DADVXV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.078"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            410..979
                     /locus_tag="KB969_002208"
     CDS             410..979
                     /locus_tag="KB969_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBB6870171.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            966..1826
                     /locus_tag="KB969_002209"
     CDS             966..1826
                     /locus_tag="KB969_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6870172.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2016..2720
                     /locus_tag="KB969_002210"
     CDS             2016..2720
                     /locus_tag="KB969_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6870173.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2725..4560
                     /gene="walK"
                     /locus_tag="KB969_002211"
     CDS             2725..4560
                     /gene="walK"
                     /locus_tag="KB969_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBB6870174.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4557..5873
                     /locus_tag="KB969_002212"
     CDS             4557..5873
                     /locus_tag="KB969_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870175.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5874..6743
                     /locus_tag="KB969_002213"
     CDS             5874..6743
                     /locus_tag="KB969_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBB6870176.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6798..7607
                     /locus_tag="KB969_002214"
     CDS             6798..7607
                     /locus_tag="KB969_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBB6870177.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7710..8339)
                     /locus_tag="KB969_002215"
     CDS             complement(7710..8339)
                     /locus_tag="KB969_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBB6870178.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8509..9801
                     /locus_tag="KB969_002216"
     CDS             8509..9801
                     /locus_tag="KB969_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6870179.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9877..10539)
                     /locus_tag="KB969_002217"
     CDS             complement(9877..10539)
                     /locus_tag="KB969_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6870180.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10764..11048
                     /gene="groES"
                     /locus_tag="KB969_002218"
     CDS             10764..11048
                     /gene="groES"
                     /locus_tag="KB969_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBB6870181.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11099..12724
                     /gene="groL"
                     /locus_tag="KB969_002219"
     CDS             11099..12724
                     /gene="groL"
                     /locus_tag="KB969_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBB6870182.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4338 a         2235 c         2803 g         3651 t
ORIGIN      
        1 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
       61 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      121 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      181 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      241 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      301 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      361 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      421 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      481 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      541 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      601 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      661 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      721 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      781 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      841 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
      901 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
      961 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1021 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1081 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1141 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1201 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1261 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1321 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1381 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1441 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1501 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1561 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1621 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1681 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1741 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1801 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1861 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     1921 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     1981 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2041 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2101 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2161 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2221 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2281 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2341 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2401 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2461 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2521 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2581 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2641 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2701 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2761 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2821 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     2881 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     2941 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3001 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3061 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3121 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3181 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3241 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3301 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3361 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3421 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3481 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3541 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3601 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3661 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3721 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3781 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3841 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     3901 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     3961 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4021 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4081 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4141 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4201 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4261 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4321 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4381 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4441 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4501 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4561 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4621 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4681 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4741 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4801 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4861 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     4921 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     4981 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5041 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5101 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5161 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5221 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5281 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5341 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5401 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5461 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5521 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5581 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5641 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5701 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5761 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5821 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     5881 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     5941 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6001 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6061 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6121 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6181 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6241 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6301 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6361 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6421 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6481 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6541 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6601 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6661 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6721 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6781 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6841 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     6901 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     6961 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7021 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7081 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7141 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7201 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7261 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7321 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7381 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7441 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7501 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7561 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7621 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7681 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7741 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7801 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7861 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     7921 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     7981 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8041 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8101 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8161 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8221 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8281 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8341 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8401 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8461 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8521 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8581 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8641 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8701 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8761 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8821 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     8881 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     8941 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9001 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9061 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9121 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9181 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9241 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9301 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9361 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9421 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9481 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9541 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9601 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9661 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9721 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9781 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9841 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
     9901 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
     9961 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10021 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10081 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10141 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10201 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10261 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10321 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10381 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10441 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10501 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10561 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10621 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10681 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10741 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10801 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10861 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    10921 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    10981 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11041 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11101 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11161 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11221 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11281 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11341 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11401 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11461 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11521 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11581 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11641 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11701 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11761 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11821 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    11881 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    11941 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12001 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12061 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12121 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12181 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12241 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12301 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12361 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12421 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12481 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12541 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12601 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12661 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12721 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12781 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12841 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    12901 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    12961 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13021 ccattca
//
LOCUS       DADVXV010000078        12758 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.079, whole genome shotgun sequence.
ACCESSION   DADVXV010000078 DADVXV010000000
VERSION     DADVXV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.079"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(51..962)
                     /locus_tag="KB969_002220"
     CDS             complement(51..962)
                     /locus_tag="KB969_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6870183.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(981..1985)
                     /locus_tag="KB969_002221"
     CDS             complement(981..1985)
                     /locus_tag="KB969_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBB6870184.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(1982..4105)
                     /locus_tag="KB969_002222"
     CDS             complement(1982..4105)
                     /locus_tag="KB969_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6870185.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(4110..6557)
                     /locus_tag="KB969_002223"
     CDS             complement(4110..6557)
                     /locus_tag="KB969_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6870186.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(6544..6933)
                     /locus_tag="KB969_002224"
     CDS             complement(6544..6933)
                     /locus_tag="KB969_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6870187.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(6993..7496)
                     /locus_tag="KB969_002225"
     CDS             complement(6993..7496)
                     /locus_tag="KB969_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBB6870188.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(7509..7733)
                     /locus_tag="KB969_002226"
     CDS             complement(7509..7733)
                     /locus_tag="KB969_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870189.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(7837..9747)
                     /gene="ltrA"
                     /locus_tag="KB969_002227"
     CDS             complement(7837..9747)
                     /gene="ltrA"
                     /locus_tag="KB969_002227"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6870190.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(10493..10630)
                     /locus_tag="KB969_002228"
     CDS             complement(10493..10630)
                     /locus_tag="KB969_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBB6870191.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(10627..11811)
                     /locus_tag="KB969_002229"
     CDS             complement(10627..11811)
                     /locus_tag="KB969_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBB6870192.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(12070..12360)
                     /locus_tag="KB969_002230"
     CDS             complement(12070..12360)
                     /locus_tag="KB969_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870193.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(12350..>12758)
                     /locus_tag="KB969_002231"
     CDS             complement(12350..>12758)
                     /locus_tag="KB969_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBB6870194.1"
                     /translation="RVYEVTGTAPTLSTKQGGTKIMIRKNETEYQEVKPEDSVNLAFP
                     NSTSRRGRLGKQSVHTLLTGDQQAIVTDQYQIRKLTPRECWRLQGFPDWAFDRDSQVN
                     SDSQLYKQAGNSVTVPVIFDIARRLKELDVHGL"
BASE COUNT         3548 a         2850 c         2092 g         4268 t
ORIGIN      
        1 aaataagtta cactacttat aacttctaat aaaattagat tgagtcatta ttatttaaca
       61 tcaacgattt tccagtttcc atttttttgt aatactaatt tgtactgaaa gtagctagtg
      121 gtttttgata cattatcaag gtattttatc tttgtactca ctagaaaatt ttttccgttt
      181 tgtagataaa ctggattctc taactccgaa aactttaagt caatattgat tggtcgcatc
      241 gcaccatttt caacataata ctccaattct ttttcagaag ctgatggata aagtttaaaa
      301 aatgtttcta aaaaatcggt gatttcttcc gttgttttgg catcaatttc tgaatcgttt
      361 tctacttgtt ttgcttcata ttttgccttg tctggctttc caatcattgt tggcaaacta
      421 gttactaaat gattcctgtt ttcatcttca aagattgtca ctcgatatgc agaagaaatt
      481 gattgcgtct tttttccctc tgtaatatgt tgctccacta aaaatgaaac gacaaattct
      541 tccgagtgtt tttcaacatc tagaattttt acagattgaa cttcggaact cgtgggaata
      601 tctgctcgaa ccatatcttg gattaaagcg agaccgtttt ctgtaaggta ctgttcgaga
      661 ttactcattc tcttttcaat tgcttctttg ttatttttcc atgaaaaata ttctttcgca
      721 aaatcctctg taaaactttc aacgccagaa gtattcacta ccttctcttt tataaccact
      781 ttttcatgag ttgtatgttg atcaatggcg gtgaaatttt tataaacgcc aaaagcaaga
      841 ctacaagaca ataaaagcca aagggcaagc accatttttc gatgcttacc cacggataca
      901 actcgttctt ttttcttttt tgggctcttt tccttttgat tccgttcaat ttttatcttc
      961 attctttttc ctcttttctc ttatttgtat cggccagctc cgataagatg ctgccgccaa
     1021 tagttttccg ttagattcgt ccaccccact ggatctcctg catgaaacat gcgattctcc
     1081 cctgcgtaaa tgcccacatg ggtcacataa gtaccggcat cataggttga atgaaagaaa
     1141 actaaatcac ctggtttggc atcttttaga tcaatatgag tcatggcatc atattgatcc
     1201 tgagccaccc gaggaagttt caggtcaact ttggcataac accattgggt caagccacta
     1261 caatcaaacc ccgtttctgg acttgagcca ccaaacacat aggccgttcc ttcatactta
     1321 aatgcctcat caaaaatttc ttggactatt ttgtcatcaa actgagttgt agttaggtat
     1381 tgcttcacta ataaacagta aaacatattg ccataattat accgccaccc accattttcc
     1441 ttaatcgcga ttgggttggg gtaatcgact ttttgaccac ctgatttttc ctttgaaaaa
     1501 gattcagcta aagcaaaact atgcttcttc ccgtttttcc cgacatgatc tagatacccg
     1561 ccaccatagt tataggcctg aataatacta tcttgatcac accctagttc tttggaacgc
     1621 ttaaccaaag acgcaaaata gagacagcct tgtttgatgg atgcctcggt acttaatgaa
     1681 ttaggtggta atccggctga ctcagaactt tgcataacgt cttccattgt gccaccagat
     1741 tccacttgaa taatcgccaa aagaattgga atatactctg ttatatccga ttctttggca
     1801 tacttttcca ccattgcacg gtgtttcaat acttcttctg agacactagt tccgccagga
     1861 gaagtgccag aactaccatt tccctcactg tcttcaccaa acaacaaacc cacacacatc
     1921 aaaataccca taaaagagat ggtcagaaaa gttaatgaaa taacacccac tttcttcaag
     1981 ttcatttttt ctcacctgac cttgattttg gacgatggtt cattcttttt tgtacttttt
     2041 gattggtctg ctttggcaga gtggacctct gtttcacttg ttggaaagaa tttttcttac
     2101 ttgctgattg gcttttccct tttgaaatga tttcttgact agttagtttt cgtttgattt
     2161 cgggattcag atttgctctc acaatccgct ttggtgcttc ttttttcagc atcatatctt
     2221 tctgaggttg agctgcttta tctattggaa tattcgccct tctttttccc tgacgatttg
     2281 ttgcttcact cagtatcttg cgtttttcgt ccattttcgc atttcttcgt tgtcgttgtt
     2341 tttctcgcaa atccactcga tccgcttttt cttggaacag tccgcgcttg aattcttctg
     2401 gtgctttttt cgacttttcg attcctttat ggagattgta tttcaaattc gttggcgtat
     2461 tccttacctg atcctttact tgtttagtct tatctttcac caaagcttgg gtatccaaaa
     2521 ctttgccgat ttttctccca gccaaattca ttcgggattg tttcttatta tttgaaactg
     2581 gattctcctt agttaagtca gatagtattt cgtgatcgtt cggtaatcgt gaattctttc
     2641 gtagagaaga accggatggc ttaaatttgg attttgattg ttcctttgcc aacttatttc
     2701 cgactgctgc accaccacca aaagccaaag ctcgtcccac atttcgattg agttgccgca
     2761 attttcgatt cattaacatt tgcggttttc gcatgacgcg tcttcccatt gactggctat
     2821 cattactctg gaggttgaac atactcataa tgtcgcccaa tttgaaatag ataccggcaa
     2881 aggtcacaat ttgcagaaaa gcaaccatga aaaatggata ggttgccgaa atattgaaaa
     2941 acatcgtgga gatgctaaat gcagtcgtaa tcaccaaagt aacacccgct cgcatcataa
     3001 tcgtattgaa taaacgaata atcgccttct ttcctaaact ttcataagtc ggcaacatgg
     3061 acaataagaa actaattggc agaaacatcg caaagataat gaagagaatt tgcgagaaca
     3121 acataatccc tgttagaaga aaaacaaaga aggaaatgcc aatattgaac aataccaaaa
     3181 agaccacggt ccctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattgt
     3241 cttcaatctc tgccttgacc gcttcttccc gatctttgcc tttgttttca tctggactca
     3301 cagatagaat cttgttgacc cggtcttcac caatttcttc tatgttggaa tcatcaaatt
     3361 gcagtagtaa ccaaggttgt tggacttgaa tcgaaaacaa actatcccga atcaaatcca
     3421 cactatcttt tccttggctt tctgaattgg gtacaacgat ctcggttcca agggtaaggg
     3481 ccgcttcact aacatctgag ctaaagtcat tgatttttgt gatataggta ggcgcataag
     3541 caatgaacga acccgatagt agaaaaatca tcacaaaatt aatcacggct cgaactgctt
     3601 tcgtggtttc tcgttttaat aatccggtat acgccacata cacccccaga gctaaaatca
     3661 tcaataatag aaacccaaaa taaaatccgg aggtctggag tccattttca gtaataccag
     3721 ccaatgtttg gatattcttt ccaatacttt cagccgtatc cgaaatgaaa tctaatttgt
     3781 aagcctcttg aaccacataa cccgtggcgt tcgacaaata caaactcacc gtccaaatga
     3841 aattagtaat ggcataaaga ccatacatca cgcttttccc taagccatca ccccaattcc
     3901 aaggcaacca atcccaagag ctatccacaa agaaatctag ttgatagttg ttcagtgaat
     3961 atttggaata tagatttcct gcttcaactg tatcatcaac tagccctgtc gcctcggcta
     4021 ccgtaccaac taaactcaat agaactatca gagtgagtat gctaataaaa acgattccca
     4081 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac aggtggacgg
     4141 gtatcaaagg catggaagag ttcttcaaag actggatgta cctgaaccac gcctacccga
     4201 ccatacaaat cctgcatcaa gcattggcca ttttccaaat ctcgtaggcg tttttgattg
     4261 ctttcatctt ctcgatccaa gccaaagaat tccaaggttt tcttgatttc atgaatatcg
     4321 gtactgcgaa acgcaaactt caacccgata ttattcttca agcgttcatc cagtaaatca
     4381 tcactatttt gcgtgacaaa gtaaaccccg gcattcatag cccgcccagc acgaacgagc
     4441 ttattcgata atgttttccc ttgcgctact tgaagaaaac tccacgcctc atctaagtct
     4501 acaattttga agatttctcg attactatgg ataaagtcca aggcaaaagt ggaaatgacg
     4561 attagcatgg aaacactaag caattccatg gtggtatatt cttcaaaagt ggtttctgca
     4621 tctggtaaaa ccaaatccgc tacttgaatg atatttaact gcctatctaa actaatcgac
     4681 tgggtaatcg aaccatctga gaaaagcaaa tgggcaaaat cataatcggt aaaggactcg
     4741 atgtgatccg cgatattttc cgcaactggt gagccttctt ttcgaagctc attaattact
     4801 tgtaataatc cccgttgatt gctttgggta accgtccgaa tggccttacg caacactgga
     4861 aacttctccc catctcgact agaaattcct gttaaaaagg tcagaatatc aattgctaga
     4921 ctttcagaat ccttcttttt ctccataatc acataaggat caagtaatcc ttgatttttt
     4981 ggcttactag ttaagttgag aatattgatt tcatccgcaa tttctggcaa ggtttctttc
     5041 cagccacccc gttccccttt tggatcgaca atcacagctt gtccaccaaa aaggacggcg
     5101 taataaacta agagattgtt actaaaggac tttccgccac cgagtgaacc gaggaatgcc
     5161 gctgctagcg cattggtaac tgaatccttg accccttgtg aggccaatgc cggtttcagg
     5221 taaacattgc gccccgtatc tacgttataa ccaaagtaaa tgccttccaa ctcccctaac
     5281 atctgagtgg cgccaaaacc aagtccggcg agaaaatcag acgtaacata ctggatataa
     5341 tcattcatgt atcgcttact agaaggtaag aattcttcat gtagccccat catatcgcca
     5401 aaaggccgga ctagttttac attggtatca tcataaaaat ctagcacttc atcacaccgg
     5461 cgctttagtt catctactga ttcggcactt actcgaacca catagctcag tttgtacatg
     5521 gattctttgg actgatccaa ggtagtttcc aattcatcta cggaatccaa tgcatctaag
     5581 acattggaat ttgtttcatt gtcagattga taggcatggt tgtccaagtc ttttaattcc
     5641 tttttcttat tgcgaacggt agcaagtgcc tttttgttcg tcacaatctc cacattcata
     5701 ctagtgtcaa ttgggaatgt aaattgttgt tgctggtaat agaaaagttc tgaggaggga
     5761 aactccattt cccccacaat tgtattaatt gttaagtacg ctacatatga ttcatgattc
     5821 tcatgttcca tgcataagta ccggggcttt tcttcaatca aacaacgact gggacgtaat
     5881 aagtcgtaac gtttcaccaa agtttccgac ttcagctttt tctttggtag ctgaaattca
     5941 tattcttcaa atggtgtacc cttttcgcca tagatatgtt caatcaaata catcagatca
     6001 ctcggtgtga ctcgtctgac tttaaatctt cgagccaatt tactttccat tagtttttca
     6061 agcttggtat atcggcgaat ttcttcattg gataaggaaa caaaatcgcc catcaaatga
     6121 tgattcactc catagacaaa ttcttgaaag ccggagaaga aagatttctt gagattcttt
     6181 agattgacct cttcatctgt cgcaatcagt ttgaagccaa taaaaaagcg ataatcaatc
     6241 tgactatcgc caatcatgga tactaatgcc tctgtctgta aatcaattcg ttgtttcgct
     6301 acttctgtta atcgcccggt aatttccttt tttgatcgtt cttgcgtggc acgaatacta
     6361 ctttctgtgg caatttgtaa ggcatgaatc ttgccttcac gattttgcgc aatcaattga
     6421 cgaaagttat cgtggacttg atatttctgt tcaggtgaca aaaaggagta attgtaaggt
     6481 attaactcat agtaggcaaa acattctccc tcttgattaa agacaagatt attttcaata
     6541 tacttaatcg ggtacatagt tcacactcct taccagagta atgggttcgt cccatcgttt
     6601 cttctgttct ttgactttct ttcctgcgaa agtgacctta aatcgtaagt gatagctaat
     6661 aaaagatcgt aaaaatccca atggtttctt accgtcaaac gttttttgcg acatgaacca
     6721 agtaactgcc accggtatac ctaagtattt taaaaaggcc ccctctatca tagatagtgg
     6781 aggcacatgg gcaaatacga tgacaaacag caaggataaa acaaaccaag ccatctggtt
     6841 aaaagtcaca ggaaaaggca gttgaaagtc attaattgca taaatgacct tttcaactgc
     6901 ccaaatactg gtgtagcttt ttattttctt catcaaatca ttcctttaaa aagaaggata
     6961 gtttagaaat caactaccct tcaataattt tgttaatatg gatactcaaa aacacctcga
     7021 ctcgttacca aataattgcc tccaatctcc aagtctctac cacacgcatc aaaatcaata
     7081 tacgtcttca agtgttctgg tacttctcca aaatcaccag cttctacaat caagaaatat
     7141 gctacatcac tcatatcatc gcaatctgga taatagataa tatcatccac atgctctacc
     7201 atctcctcaa aagaattgaa gaaagcatgt tgaatctcag aagcaacttc accaactggc
     7261 gttccttcaa gttcctccgc taagccacac aaccgattaa tttcctcaat tggcgtatac
     7321 tcatcaatct caaagggaag ttcataatca tgaattgcat attcctcgta ttcgtcattt
     7381 aacccaattc gttctttcac ttcatcaaaa tcgacaggtg gggtaaacca cgcccccacc
     7441 aattcacctt cgttatattt cccgaggttc gcaatataaa cacgcatctg ttccatcgtg
     7501 cttccccctt acgcaccgac aattcggtta aacaaactga gtaagacatc cttcacccca
     7561 gaagcattaa agaccaatcc gaccgcaatc aaagcaatca ccaaaaagcc aatcagtttg
     7621 gaaaactccc gcttaaatcc taaaaacaaa ccaatgacca caattgccag taagactaag
     7681 gattgggcat tggttaaaaa ccattgatat atggataggt aagttcctga tattataaat
     7741 atctcaaact tttcccccca ttcacacgga gcgtgcgact ttcaccgcac tccgcgttcc
     7801 atcgtgttta tattgaaaag tatttatgta gtagacctat atcaagttta attcttgatt
     7861 gccagctaat actctatatt tatttagtct tatgagctgg actttattta gcttcaatag
     7921 agctatatat ttttgtattg tttcttctgt tttagcgtgt attagacggt gtaccgcctc
     7981 ttttaccaaa ataagatttt tataatcgtc atttccacca gctccagttg gtacaatatg
     8041 atgacaatgt atttcattag cttgttgaaa ttcttccaga gttatagcac attttccatg
     8101 ttgagcagaa aatagcgaaa ttcgattgtc tgcgtattct attgtgcgat tttccaaaga
     8161 taatttcatt aactggtaca tcagtaattt atcaacactt agattggtgt ggataaattt
     8221 tcttccctct agagtgtagc aattcgctaa atacaccttt gccattggtt ttctgtgttg
     8281 gatatatcca acagggaaaa taggttcgcc ctcgccagca acataccgaa gcattttaga
     8341 tttaccatat cttgttgcct cctttgtcgt aagttgtctg cctgtttttc tcaatctgcc
     8401 ccttttgttt gtacctaatc tgttagtgaa gatagccatt acagctctat tcagtttcat
     8461 acaatccaga tttacattcg ttgcaatctg ataataattt tgcataccta ataccattga
     8521 attataaagt cttgtttctt ctaattccgt tttccctttt gagggagaag caattttctt
     8581 tgcctgtgat accagcttgt ctttttggtt tttgaattgt ttatcactta tatgtgattt
     8641 aacaactaac ttctttcttc tcggtatcat tttaatcttg aaaccaagaa agtcggagta
     8701 tctttttcta acatttacaa ttcttgtttt ttcttgtgat acttccaatt ttaatcgttg
     8761 ttcaatccat tgagtgattg ctattttggc tttttcagca ctttccttgt agcggcagaa
     8821 aactctaaaa tcatctgcat aacgaaccat atacatttcc tttaactttg ttttcttcat
     8881 ttctttgtaa gcgttgcttt tacatgggct accgctttta ttgatatgaa ccacatagtt
     8941 ttttgtaaca ggattttcct gccattggct ttctacccaa tggtctaact cattaagaac
     9001 aatgtttgct agtagtgggg atattattcc cccttgcgga gttcctttct ctggatatgt
     9061 tattgtaccg ttagtcattt tgattggagc ttttaatatc ctttttaaaa tgaatatcaa
     9121 gtgcttgtcc cgtattccca tagcccatat ctgttttatc agcttggaat ggttcacgtt
     9181 gtcaaagaaa cccttaatat caaattcaat cacataatgt agctggctga tttgtaggcg
     9241 gttataggtt gcttttattg cattttcaac tgacctatta ggtctaaaac catagctgtt
     9301 ttcactaaat ttagcttcgc agattggttc taatacttgt tttatacatt gttgtataag
     9361 cctgtcccac atacaaggaa tacctagagg tctggtttta ccatttggtt ttggtatttc
     9421 ttttcgcctc actggcttag gtcgataccc atgtggactg cctgcaacaa tgtatcttac
     9481 ttttttgaca actgtttctg ctggcaattt gccaatatct ttaattattg taccgtctgt
     9541 tcctgctgtt ttactgcctg catttgcttt gatatttcga tatgccagta atatattttc
     9601 tctcgatagg ataatatcca taagatgagt gaaaatatct ccattcttac ttttggcata
     9661 taaatcatca aaggtgtttt gcatttcgta atattcagcg tgtcttaaat cttctacaca
     9721 caatgtttca tttttatttt taggcataag gcttcactcc tttacttgaa attgagtgag
     9781 cttttttatc ttactcgtaa tccttattga aacaacataa tacttttcta atatatacac
     9841 gacttgaggg cattcctcca ttctcattac aagaatttct taggttcgcc ctctgctttt
     9901 cagcattagt tcaactgctt attgttcttc gtcagtttat tctcttgatg agaacccaat
     9961 acctttcctc gttccgataa tcttatctat acatatatat ccttaggtca ctagctataa
    10021 gcctgctggc ttgataccgc ctgtaacgtt atatggcatt tcataaccta tattcttact
    10081 ttgccacacc agctacgatt tctcgtacct ttgcatttct acaaagttca aatttagacc
    10141 cgtacattcg ctgtttcgtc agttccttat agaacattct aaccatagat attttataga
    10201 cccccgacct gttggatacg ctacccacct ctggatagtt ttcgatagaa gatatatgtt
    10261 catcaactat tacggtatct ttcagccgtc tttaccgagc ttcaaacatt ctgagtttcc
    10321 tcatacaatg cttgtcggag gctcagggca ggcgtttcag agcgttactt catcattcca
    10381 cctgtcagat tatcagttct cctaataacc aaactttttc gttcttttat tagtgcctta
    10441 gcttttcact aaggaacgag tcgcacataa attttgtccg aaattcatct tgtcactttc
    10501 ctttcttttc cattgctcga tccgctgctg cacttgcatt catcaagcac atcacagtaa
    10561 caccaagcat actgccacca aataccaaaa aaatatcttt tacaattccc atgacgattc
    10621 ctcttttcat ataatcaaat tttcaattgc catactttgt tgctccaaaa tctttttatg
    10681 tcggtctgat aagcgtgcat tctgtaccat atcctggata taggttgtcc gattcaatcg
    10741 atccaactcc ttagccattt tccacgtagg ggcgacttgt cggcctagcc aattcaaggt
    10801 tcgttcaatg gtatacggtt ttggctcgga agttaattga atctctttcc gattccgtcc
    10861 aataaaacgc ccccattgtt cattcaaggg ccagttggtt cgccttttac cttctacttt
    10921 atccgcaaat cgcaagtaac gattgataat ggaaaacgtg gtgctctcaa tgctacgacc
    10981 ttttaacaaa tcttgaatcg catgaaaagc acggtcattt ttcagtcgaa tctcaaaacg
    11041 atttttcgtc tcagtttggt ctaatggaat ccctaacttg atatattgtt catagtcttt
    11101 ttcatacaaa cagaaataaa cctcactctt gagactgccg atatataagg tattgcccat
    11161 gccgtccttt tcatcagcct ttaaaagttc cccggaacga taacttttaa aggtacgaaa
    11221 caaggagata cattcttcct tctgacattt tttcgttagc tcaggtatat ccaatagccc
    11281 cactcgatca ttgattgcca agtccaagcg tttcatcacg ccaccggcct ttagacaatc
    11341 ctcgaaaaag tcgtaccagc tacgcttttg agcgagtaaa aaagtttcaa attgtcggca
    11401 acctcgcccc tttaattcta aaagcacacc tttatcttct tcatgagaca acatcaccac
    11461 aatatcaccc atgacatact gttcttgata ggagtaaaag gcataatctt catggagcat
    11521 atactcaaat ttcaaatgga gaatttcttg aataattttt cgtgcatccg ttgtgggaaa
    11581 gcgaatcctt acatagtcaa acagtaacgt caaaggcaaa tcgggattaa agctttccag
    11641 ttggtcaaaa attttcctca tggtttttat agatgcggtt acgccaccat tttctatctg
    11701 atttaagtac ggccgactaa gtccacaagc cgtagccaat ttattttgtg aaacgccgta
    11761 ttcgttgcgt cggtctttta atagccgata atctaaattc cgttgtgcca agttctcacc
    11821 tccaaattca aggtgttaac tttttcaaat gagttaacac ctatacaaat tacttactat
    11881 ctttgataca acaagcattc ttaatggttg cttacttatt ttttgtgttt ttgtaccccc
    11941 ctgttagata cgggggtgag acatcatggt cggctaacgc cgtccatgaa caggcacagc
    12001 accacggagg atttctgctt cgcgaatcct ccgcggtcag cgcctaacag tcagttgtgt
    12061 tggtttaggt tactcatctg taataccatt tacttccaac tctgctttca tttctaacaa
    12121 gtattgacga atatctggtt cttttgcttg gtccgcaatc cgctcaaatt ctgcaattac
    12181 ttgatttatt tcaattcgag catccgtctc ctcattcatt aaatatggat cgccagcgac
    12241 tttgacacca ttcttgcgaa tatcaaattt taaccgtcgc aattgttctt ctaattctgg
    12301 gtctgactga atctttccaa tcacccaata aatttctcca atcaactcat cataaaccat
    12361 gtacatccaa ctcttttaat cttctggcaa tatcaaaaat gaccggaact gttacagagt
    12421 ttccggcttg cttatacaac tgactatctg aattgacttg agaatctcga tcaaaagccc
    12481 aatcgggaaa gccctgaagt cgccaacact ctctaggtgt tagcttccga atttgatact
    12541 gatccgtgac gatcgcttgt tggtctcctg ttagtaaggt atgaacactc tgttttccca
    12601 gacgacctcg gcgacttgtg gaattaggaa aagccagatt cacactgtct tctggcttca
    12661 cctcttgata ttctgtttca ttttttcgaa tcatgatttt tgtaccacct tgtttcgttg
    12721 acaaggtggg ggcggttcca gtaacttcat aaactcga
//
LOCUS       DADVXV010000079        12740 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.080, whole genome shotgun sequence.
ACCESSION   DADVXV010000079 DADVXV010000000
VERSION     DADVXV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.080"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            99..542
                     /locus_tag="KB969_002232"
     CDS             99..542
                     /locus_tag="KB969_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6870195.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(548..1732)
                     /locus_tag="KB969_002233"
     CDS             complement(548..1732)
                     /locus_tag="KB969_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBB6870196.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2000..2698
                     /locus_tag="KB969_002234"
     CDS             2000..2698
                     /locus_tag="KB969_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBB6870197.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2705..3382
                     /gene="nth"
                     /locus_tag="KB969_002235"
     CDS             2705..3382
                     /gene="nth"
                     /locus_tag="KB969_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBB6870198.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3508..4041)
                     /locus_tag="KB969_002236"
     CDS             complement(3508..4041)
                     /locus_tag="KB969_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870199.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4338..6719)
                     /locus_tag="KB969_002237"
     CDS             complement(4338..6719)
                     /locus_tag="KB969_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBB6870200.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6709..7356)
                     /gene="recU"
                     /locus_tag="KB969_002238"
     CDS             complement(6709..7356)
                     /gene="recU"
                     /locus_tag="KB969_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBB6870201.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7420..7959
                     /locus_tag="KB969_002239"
     CDS             7420..7959
                     /locus_tag="KB969_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBB6870202.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8049..8468
                     /gene="gpsB"
                     /locus_tag="KB969_002240"
     CDS             8049..8468
                     /gene="gpsB"
                     /locus_tag="KB969_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBB6870203.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8490..8857
                     /gene="rnpB"
                     /locus_tag="KB969_002241"
     ncRNA           8490..8857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KB969_002241"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9066..10232
                     /locus_tag="KB969_002242"
     CDS             9066..10232
                     /locus_tag="KB969_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBB6870204.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10278..11774
                     /locus_tag="KB969_002243"
     CDS             10278..11774
                     /locus_tag="KB969_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBB6870205.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11855..12538
                     /locus_tag="KB969_002244"
     CDS             11855..12538
                     /locus_tag="KB969_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6870206.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3607 t
ORIGIN      
        1 tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg aataggaaac
       61 aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga caactgctaa
      121 tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca gaaatggaaa
      181 aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc gggaaaatcc
      241 ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga gccatcagta
      301 agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc gaagagaata
      361 aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat agacacgagc
      421 aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg tcaaaagaag
      481 aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga agtagcaaat
      541 gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa aatccgaata
      601 ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg ccgatgacgc
      661 gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg ttatctgaga
      721 cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg aaaccataac
      781 agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat gtgatgaata
      841 gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct gaaaattttt
      901 tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca atcaaagaga
      961 agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat tgagaaaaga
     1021 tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat aaaggaataa
     1081 cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg gagaaactta
     1141 aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag ccataaacgg
     1201 catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc aactcagcta
     1261 atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca cccatccatc
     1321 caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca tataaggtgg
     1381 agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc catatcgaat
     1441 ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata ataaggatcg
     1501 gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag aaggcagcta
     1561 gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg gagtgagaat
     1621 aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat ccagtgaata
     1681 agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac atgtaaaaac
     1741 tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt ttgtttcctt
     1801 gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa agtgaagata
     1861 cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc tgaccgatca
     1921 gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac gtatactgtg
     1981 attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg gacaaacagt
     2041 catatctaat cttttactta aaaattatca taggatcggt ctacaatctg aagaattttt
     2101 atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg atttgcagat
     2161 gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg atcgtctcgt
     2221 aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag cagatcgata
     2281 taatctttac cccatctatg atctattagg tgagtattta aaaacacaag aaaaaaaata
     2341 cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg aacaagaatt
     2401 tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag aagaagacca
     2461 ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc aggcttatag
     2521 ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac gtacaaaaca
     2581 acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag aagtagaaca
     2641 gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg aggagtagcg
     2701 gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg gaatgtttcc
     2761 cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg cagtgatctt
     2821 aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt ttgcctcttt
     2881 tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta aaataaaaac
     2941 gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc agctgattga
     3001 acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc ctggtgtagg
     3061 cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa tcgcagtaga
     3121 tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg ctacggtcat
     3181 ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa agacacatca
     3241 tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt gcgaggtatg
     3301 tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag aaaaggcgct
     3361 aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg tatgaattat
     3421 cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa gtaaatgtac
     3481 atactcagta gctaggatgg taacttatta caatttattg cgataaaaat aaaagttgtt
     3541 atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac ctataaaata
     3601 agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag gtgtaataaa
     3661 aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa tggatttggg
     3721 cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata aaaaagtgag
     3781 aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc ttaaaagtac
     3841 agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta ataataaaca
     3901 aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata aaaaaagatg
     3961 gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga agccttcttt
     4021 caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa tgggattatt
     4081 aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta taaacaagta
     4141 aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt taagctaaat
     4201 gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat acagcttggt
     4261 acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc acgcttgtag
     4321 acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg
     4381 tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat
     4441 gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc
     4501 tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta
     4561 gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag
     4621 ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct
     4681 ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt
     4741 gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac
     4801 gattctgaag tgacaggcgt cattttttta ttgtaacctg tccacacgga aatcgaataa
     4861 tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt
     4921 gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg
     4981 atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata
     5041 taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg
     5101 tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa
     5161 gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct
     5221 tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt
     5281 tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca
     5341 ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag
     5401 tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca
     5461 gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa
     5521 ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg
     5581 tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca
     5641 acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt
     5701 ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc
     5761 ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta
     5821 gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct
     5881 tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct
     5941 cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc
     6001 atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac
     6061 atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag
     6121 taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct
     6181 tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc
     6241 aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca
     6301 gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc
     6361 gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt
     6421 tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta
     6481 gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct
     6541 acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat
     6601 aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca
     6661 ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt
     6721 cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg
     6781 aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg
     6841 tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt
     6901 caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg
     6961 ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga
     7021 tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt
     7081 atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt
     7141 aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc
     7201 gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt
     7261 gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt
     7321 ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca
     7381 ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc
     7441 tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc
     7501 caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa
     7561 tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa
     7621 ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt
     7681 aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat
     7741 gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt
     7801 tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa
     7861 acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg
     7921 ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat
     7981 caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag
     8041 gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa
     8101 caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag
     8161 attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg
     8221 caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag
     8281 aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg
     8341 aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac
     8401 ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc
     8461 aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca
     8521 ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa
     8581 accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat
     8641 gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga
     8701 acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa
     8761 gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct
     8821 ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag
     8881 gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa
     8941 tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat
     9001 ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat
     9061 tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag
     9121 cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg
     9181 cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag
     9241 atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa
     9301 acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg
     9361 gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag
     9421 caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa
     9481 ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg
     9541 atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat
     9601 tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat
     9661 tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata
     9721 atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag
     9781 aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag
     9841 atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag
     9901 aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg
     9961 ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag
    10021 aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga
    10081 gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca
    10141 aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc
    10201 gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat
    10261 gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc
    10321 ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag
    10381 ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa
    10441 tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg
    10501 aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac
    10561 cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa
    10621 aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat
    10681 taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc
    10741 tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta
    10801 aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag
    10861 actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg
    10921 aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga
    10981 ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa
    11041 tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg
    11101 ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat
    11161 cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt
    11221 tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt
    11281 cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc
    11341 tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg
    11401 ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa
    11461 atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc
    11521 cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa
    11581 tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag
    11641 agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac
    11701 atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat
    11761 atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt
    11821 tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga
    11881 ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag
    11941 agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac
    12001 gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga
    12061 ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc
    12121 gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga
    12181 actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat
    12241 cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga
    12301 actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa
    12361 tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga
    12421 agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg
    12481 gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg
    12541 gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac
    12601 ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga
    12661 acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg
    12721 gcaggagaac accgtttatt
//
LOCUS       DADVXV010000080        12732 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.081, whole genome shotgun sequence.
ACCESSION   DADVXV010000080 DADVXV010000000
VERSION     DADVXV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.081"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="KB969_002245"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="KB969_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6870207.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="KB969_002246"
     CDS             complement(322..891)
                     /locus_tag="KB969_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBB6870208.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="KB969_002247"
     CDS             1077..1979
                     /locus_tag="KB969_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6870209.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="KB969_002248"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="KB969_002248"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBB6870210.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="KB969_002249"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="KB969_002249"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBB6870211.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="KB969_002250"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="KB969_002250"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBB6870212.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="KB969_002251"
     CDS             8547..8732
                     /locus_tag="KB969_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBB6870213.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="KB969_002252"
     CDS             complement(8794..9990)
                     /locus_tag="KB969_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBB6870214.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="KB969_002253"
     CDS             complement(10160..11596)
                     /locus_tag="KB969_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBB6870215.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="KB969_002254"
     CDS             11889..12698
                     /locus_tag="KB969_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6870216.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2672 c         2250 g         4009 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt ga
//
LOCUS       DADVXV010000081        12630 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.082, whole genome shotgun sequence.
ACCESSION   DADVXV010000081 DADVXV010000000
VERSION     DADVXV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.082"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="KB969_002255"
     CDS             complement(52..1581)
                     /gene="ahpF"
                     /locus_tag="KB969_002255"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBB6870217.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="KB969_002256"
     CDS             complement(1591..2154)
                     /gene="ahpC"
                     /locus_tag="KB969_002256"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBB6870218.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(2298..2960)
                     /locus_tag="KB969_002257"
     CDS             complement(2298..2960)
                     /locus_tag="KB969_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6870219.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            3144..4790
                     /locus_tag="KB969_002258"
     CDS             3144..4790
                     /locus_tag="KB969_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBB6870220.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4781..5863
                     /gene="uxuA"
                     /locus_tag="KB969_002259"
     CDS             4781..5863
                     /gene="uxuA"
                     /locus_tag="KB969_002259"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6870221.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(5971..7524)
                     /locus_tag="KB969_002260"
                     /pseudo
     CDS             complement(5971..7524)
                     /locus_tag="KB969_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            7672..8813
                     /locus_tag="KB969_002261"
                     /pseudo
     CDS             7672..8813
                     /locus_tag="KB969_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(8939..10018)
                     /locus_tag="KB969_002262"
     CDS             complement(8939..10018)
                     /locus_tag="KB969_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBB6870222.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(10121..10561)
                     /locus_tag="KB969_002263"
     CDS             complement(10121..10561)
                     /locus_tag="KB969_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6870223.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(10618..11028)
                     /locus_tag="KB969_002264"
     CDS             complement(10618..11028)
                     /locus_tag="KB969_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBB6870224.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(11208..11642)
                     /locus_tag="KB969_002265"
     CDS             complement(11208..11642)
                     /locus_tag="KB969_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6870225.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(11742..12590)
                     /locus_tag="KB969_002266"
     CDS             complement(11742..12590)
                     /locus_tag="KB969_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6870226.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT         4220 a         2351 c         2243 g         3816 t
ORIGIN      
        1 tcttgtcacc atcctttttt ccgctctctg actttttaca atcttcatag ctcaagtgcg
       61 catcagataa tcgaatgctc ctaaagctgc agtagctcct gaacccattg aaacaatgat
      121 ttgtttgtat ggactatctg tacaatcacc agctgcgaaa acgccgggga tattcgttgc
      181 gccatttttc tcggtcacta tttcatttct tggattcatt tcgatcgttc catctagcca
      241 atccgtatta gggagtaagc cgactagaat gaatactcct gaaacagcta gtgtatgcat
      301 ctccatcgta cggcgatcga tataggagag agattctacc tgattcgtac cgctgatttc
      361 tttcgtcgct gcatgtttga taacagtgac attcgcaaga gagactagtt tatcctgtaa
      421 gatttgatct gcttttaatt ctggtaagaa ttctagaaca tatacatgtt ttgctaaccc
      481 agccaaatcg attgctgctt caacaccaga attaccacca ccgataacag caatctcttt
      541 tcctttaaat aaagggccgt cacagtgtgg gcaataagca attcctttat ttttaaactc
      601 tttttcgcct ggtacattga tagaacgcca gtgcgcacct gtcgcgatga tggcggtttt
      661 tgctttaagt gatataccgt tagctaagcc aatattaata aaatgttgct ctttatttaa
      721 ggaaacggcc tgttgattca tcataatgtc gatagggtaa ctacgcacat gactttctac
      781 ttgctgcatc aattttggac cttctgtgta agaggtacca atcatatttt caatccctag
      841 tgtttcaacg acttgtccgc cgaaagaatc agcgacaagt cctgtacgga ttcctttacg
      901 tgctgcatag atagctgcac tactagctgc tggtccaccg ccaatcacta atacatcata
      961 aggttctttt tcaaacaact cttcttcaat caaagggcca gtgatttttt caacaatttg
     1021 ttcgatcgtc atgcgtccgc tactaaattc ttctccattt aaaaacacag ttggcactgc
     1081 catgattttt ttatcatcga tttctttttg gaacatccca ccttcaatca tcgtatgagt
     1141 aatatttgga tttaatacag ctaatatatt caatgcctgt acaacgtcgg ggcaattatg
     1201 acaagtcaag ctaacataac tgtcaaaatg caatgtttgt gttatttttt tgattttaag
     1261 actcaaagat tcactgattt tcggtgcccg tccactaatt tgtaacatag ccagtaaaaa
     1321 agaggaaaat tcatgaccga gggggatacc agcaaaaacg attccacttt ctttgccaac
     1381 tggattgata gaaaaactag gtgtgcgcat cgaatctctt ttttcccaag agattttagg
     1441 agacatttct gctatttcct tcgtaaattc agctagtttt tgactatttt cactattatc
     1501 caaactaaca gaaaaaacaa taggagattc aatcagtgct aaatattgtt cgagattttg
     1561 tttagtttct ttgtctaaca tatccaccac ctaaatcttt ccaacaagat caaaacttgg
     1621 tttcaatgtt tcgccacttt ctttccattt tgccggacaa acttcacctg ggtgggtacg
     1681 tacatattga gcagcgcgaa tcttatcaat cagtgcacta gcgtcacgac cgattccatc
     1741 tgcattgatt tccatagctt gaacgattcc gtctggatca ataataaatg ttcctcgctg
     1801 agctaatcct tgctcttcat ccaaaacatc aaaaatacga gaaatctgat gagacggatc
     1861 accgatcatc acgtattcga ttttaccgat agcatctgat gtatcatgcc atgctttgtg
     1921 agtaaagtgg gtatcggtag agcaagaaaa gacttcaaca cctaaagatt tcaatgtact
     1981 gtattgttct tgtaagtctt ctaattcagt aggacaaaca aaagtaaaat cagctggata
     2041 gaagcaaaga atactccagt tccccataag atctttttca ctgacttcta aaaattctcc
     2101 ttgatgataa gcatgtgcat taaattcttc gatttttttc ccaatcaatg acatagtaaa
     2161 acctccaata ataattattt atttataatt attgtaattt agttggagtt gcaaagtcaa
     2221 tggatatttt gttatttaat aaagattact caaaaacgaa ggttaattat aaaaatagaa
     2281 gaggtcgcaa gaaaatgcta ctgctggaaa tactcgggat aacgttgagt aacagtttcc
     2341 tgttctttca gcatcatgtg taagtgcaat cccgtttgaa atcgagcttc ttctggtttt
     2401 ttatcaacta aagccttgag taaatcataa tgttgttcca tgatcgtttc ccatggaagc
     2461 ccctgaatgg tcactcgtaa ccagcggaaa cgttctaaat gggtattatg gtcatctaac
     2521 cagttccaaa cttcttttct tcctgcaatt tcgaaacaag cttcatgaaa taaattatct
     2581 gcacggaaaa aagcgcgttc gtcatttatt ttgactgctt tttcttgttc ttctaaaatc
     2641 gtttctagca ctattcgtgt ttgtgtgtcc aatttggaac aacattcaat catgatttgc
     2701 tcttccaact gttctcggac aaagcgagca ttttctgcag aaacaagatt aattttggaa
     2761 acatacgtac cactttgagg tatcgtatac acgagttctt gctgacgtag ttgaatcaat
     2821 gcttcgcgaa tgggagtccg gccgatagca agatgttcct ccagtgcctt ttcagatatt
     2881 ttccttccag gttctaagtc agcatagata atttgtttac gaatcgcttg ataagcttgt
     2941 gattgcaagc tgcttttcat ctttattcct ccaaaatcat ttctatgaac gtagtataac
     3001 agaagaggtc tgaaaaacaa tctggtatgt cacattaact agtaaatttg tataaatagt
     3061 aaaattttgg ttgacatagc gatttttatt gcataaaatt cacttgaata caaaaactaa
     3121 tatgttagtt taggagggga aaaatgattg atttaaacaa ctggaggaac tttatccctg
     3181 aattatctca aaaagaagta gaaatacctc attttgaccg tgcatcatta agagaaaatg
     3241 gacaaaaaaa tcctgtctgg atccatttcg gtggcggaaa tctttatcga ggatttcatg
     3301 cagaaatcgc tcaacgttta gcggatctag gcgaattgtc cactggtgtc attgtttgtg
     3361 aaacattcga tgaagaaata attgaaaggg cttaccaaga ttttgatgat ttgattcttg
     3421 aagtggtcat gccaagcagt ggagagttcg tcaaacgtat attagctgcg acagctgaca
     3481 gtctgtattg tcatccagat tgttctgaac actttgataa gatgattcga cactttgaaa
     3541 atcctagttt acaattagtt acttttgcta ttactgaaaa aggttatcga ttgaaagata
     3601 caaataataa atatatagga ccgattgcag tcgatataaa aaatggtcca aagaagccat
     3661 cacatacaat gagtattctt gctgtgctac tttataaacg ttttttatct ggagcttggc
     3721 cgattgcact tgtctctaca gataattttt cacaaaacgg tagtcaatta cgtacttctt
     3781 tgctaacgat cgcaaaagaa tggcaaaagg aaggttatgt acaaaataca tttatccaat
     3841 acttatcgaa tgaagaaatt gttgcgtttc catggacgat gattgatcgt atcaccccga
     3901 atccttcctt gtcagttagc aaaatgttgg caaaagaggg cttttcaaat atgtcgattt
     3961 tccaaaccgc aaaaggaaat aatattgctc catttgtcaa tacagaggac atccattatt
     4021 taatcatgga agatcatttt cccaatggac gtccgaaatt cgaaaaagct ggggtattct
     4081 tgactgatcg tgcaacggta gataaagcag atacgatgaa ggtgacgact tgccttaatc
     4141 ctttgcatac gtctttagct attatgggtt gtttactggg gtataggagc atagctgagg
     4201 agatgaaaga tccagattta tcgctgctag tttctgaaat cgggtacaat gaaggcctcc
     4261 cagttgtgga gtctccaggt atcattgatc caaagatctt tctggaagaa gtaattactg
     4321 tgcgcttttc taatccaaat attcctaata tgcctcagcg aatcgccacg gatacctctc
     4381 aaaaggtggc gattcgttat ggtgagacga ttaaaaaata tatggaaata gaagttaaag
     4441 acccgcagac acttgtattc ataccattga ctctcgctgc ttggcttcga taccttattg
     4501 gcattgatga tcaaggaaaa ccattcatcc cgagtccaga cccactattg acagaccttc
     4561 agcataagct ttccgatatt caactgggta cgcaagatac atcacatatt catgagaaaa
     4621 tggctcctat tttgtcaaat aaagaaattt ttggtgtaga tctttaccaa gcagagcttg
     4681 gcagaaaaat agaagaaatg ttcatcaaga tggtagcagg accaaatgcc gtacgaaaaa
     4741 cattacagga ttacttacaa gaacatggag gaaatttatc atggaaatga cttttagatg
     4801 gtacggatca caggaagaaa agattacctt agatgaaatc agacagattc ctgcggtcaa
     4861 agggattgta ggcacattga tggatatacc agtaggagag gtatggccta gggagaggat
     4921 caaagaacta aaagaagaaa ttgagtctcg tgggttaaca ctaaaagtaa ttgaaagcgt
     4981 caatgtgcat gatgccatta aaattggatt accttcccgt gagcagtata tcgaaaacta
     5041 taagcagaca atccgaaact tggcagaata tggaatagaa gtcatctgct ataattttat
     5101 gcctgtattt gactgggtga aatctgacct tgactaccgc ttagaagacg gctcatccac
     5161 gttagctttt atatctgatg atattccaga tgatccaaga gaaatcgtcg cgcgcatcga
     5221 acattccagc aatgaatttg gattgccggg atgggaacct gagcgcttag ctcctatcaa
     5281 atccttgctt gaagcctatg catcagtaga cgaagaaaaa cttcgagaaa attttgccta
     5341 ttttctccaa tcaatcatcc caacatgtga agaggtaggg gtcaaaatgg ctgtacatcc
     5401 agatgatccg ccatactcga tttttggatt agctcgaatc gtaaagaatc gagaagattt
     5461 agattggttg tgtcgcatag tagacagccc ttataacgga atcactcttt gtacagggag
     5521 tattgcagaa gatccagaaa atgatgtata tgggatttta gcagaatttt gccaaagaga
     5581 tcgaatccca tttgcacatg ttcgaaatat taaattttta gctaatcgag atttctatga
     5641 ggcaccacat aaatccgaat acggttcatt agacatgtac cgcatactaa aaacaatgta
     5701 tgacaacgga tttaacggat acatccgtcc tgatcatgga agaatgatct ggaatgagac
     5761 aggaagacca ggatacggct tatatgatcg agcattaggt gctgtttatc taaatggatt
     5821 atgggaagca atcgaaaaag gaaacaaaag taaagataat tagtgaaaaa aactgtaatt
     5881 ttattatgta aataagaagg atgttcaaat tcttgataca taaatccgga ggttgttaat
     5941 aagcattcgg atttatgtat cttatttggt ctaggaagta acttgatttt cttttttcga
     6001 ttgatccatg agtgcttctt cttttaattc aaagatatat tctgagatcc tcataatcac
     6061 ttttttccag tcttctggtg tgatgattcc ttttaaaata tagatttttt tgatatgaga
     6121 aggcaattgt ttcaaagggc agtcgctgat aacgatgttg cagttctcca taaaatcatt
     6181 ttgtattttg atcgattcat ttgaaaaaat ttgttctatc ttaacgatca gatctttact
     6241 gatataaaaa tcacgcgtat agttcacacc aatcacaatt cgcggctgtt ttttgtagcg
     6301 atcatacaaa tgtactaggt cttcaaccat ccattgcaca ttttcctttt ctaaaataac
     6361 tggtaacaag tgttgatttt gttctctgaa atccatataa aattgttcaa tggcggtttg
     6421 gacttctttc aatacgctat gttcttgata aagcatgaaa gtaggaaggg gcgtatttgg
     6481 ttgattgaag ttaagaaatc cattataaag tttatttcgt gcgaatgcca atgagtaaag
     6541 aatcttttct ttttcaggta taaacaaatc aaatacagta caaagggact ccaccatttc
     6601 tcttgaataa agaacatgag gaacgtttgc tttttttaaa agtttgtatt gctccaagct
     6661 tgtttcttcc gattcgattt tcgtgataga aagtcgagct aaaatattca ctaagatgcg
     6721 ttgttcgcga caaattggca gattaggtcg caaaatatct acagagagat caataaaaaa
     6781 gtcaatatat tcatactctg tgaattcttt ttgtacgtct ttcacagaag ttgcaggaaa
     6841 attctcttta catattttta atagaaaata taatttatct atcataccgc tatttagtcg
     6901 gtcaagtact tcttttttaa aaaaagtatt catcataaaa gccactactt gcggatcttc
     6961 atcataaaat tctgtagcag tacttgaaaa gatgttccaa taaatatcta atgctgcata
     7021 ttgaatttgt acctcttttc cagaaaaaga ctttctgcca ttattagaaa aggagataga
     7081 caaaccgtac tatgctaaaa atgcattaat ctttttcatt ttcgtataca aataagaggc
     7141 actatagttt gtttgctgac tgaaactgat aatcgaattt gtctgacagc tgaacaaaga
     7201 agtcaagatc tgataactga ctgattcgtt gcagtatctt ccaaatagac gataatagca
     7261 gtaagccgga tcaattcctt caaaattcaa ctttaaaaaa ggtttttgct tatcaatatg
     7321 cagttctgtt agattgagac gctcaaagtc ttgttctaat tctttgatgt atagtaaaaa
     7381 atttgattca gacatatgga aatgatctgc taaatattgt gtagtaataa agaaacgatg
     7441 ttcagatagg aaaagaaaaa tatctaattt tgtattgctt tttttcttca agataaacgt
     7501 tttaatcgct tcttgagttt gcatgaaaga ggctcctttt tacttaaatt gttaaaactt
     7561 gaaaatatta ctgttttttt cataaattta gacaaaaaaa cagtaaacat ataggtagaa
     7621 tctctactat cttatttctt gcatacaaaa aaatcaagga gtgagagagt tatgagatat
     7681 tcaaccatct taatatcaac atttgcagcc ttaagcttat cgcttactat aaatcagaca
     7741 gtccacacag aggagacaga aacagccaaa tggacagaaa ccaagtgggc caacgtcaat
     7801 cgaattacct ttcaggatga attttcatcc ttcaattcag gagtcgcaaa attaagaaaa
     7861 ggacaaacag cgaccatcaa agcaaaaatt gactattcgg gagacttagc acctatacta
     7921 caatcagctg ttacatttga gaatgttgat cccactttgt cgattggcta tgacgagaac
     7981 actttgacta tccaacacaa gcaagcgata tttaccttca ccgttacatt aaatcaggac
     8041 ttgttaaaac cagcgctttt tactgtcaag gtatcagatg gactaccgaa cgatcatcat
     8101 ttaacgccgt atagtcagcg gcagacaatt gagcaagatt cagccatcga ctcaggagga
     8161 gatcttgttg aagaaccaac agataaacca gaaaatgaaa ataagccaga agtaccgcct
     8221 acagaaaatc cagacggaga acagaaaccg gaaatagaac ctggagaaga acccgataca
     8281 gaaactcaac cagagccaga caataaatca aaacctgaaa taacccctgg agaaaaacca
     8341 gatgtaactc cagaaccaga tacggattct ggaaaccaaa cagtaccgga aacaaatcca
     8401 gacacagata atgaaactga aaatccagaa aaaccagagg tagatccaga agaaaaacca
     8461 gatgtgactc cagaaccaga tacggacgca agagaccaag gaataccaga aaaaataaac
     8521 aaaaaaacaa ttcaagagga tggaaaaaaa gagagtaaaa aatcaaatct agcaattcta
     8581 aaaataaatg aagagcagct gaataaaaaa tcacgaatat ttgatagcgc ccaatcagct
     8641 gaaaccttaa aaagtagcaa ggatacaacc tttgctgtcc tgaaacgaaa aataaacagc
     8701 taccaaaatc cggagagtca caaaacaaag ttatactgtg gagcggaatc attctattaa
     8761 gtatagcaac aatgctttct gcaaaaagat ttaaacaaaa cagatctctc taacatttga
     8821 ataatgtctg tgaacgcatt tttcaaataa aaagaaatat ccagaaaatg accccaaaat
     8881 accagattga aatctgatat ttggggtcgt tcatacttta tctttcttca tatttatttt
     8941 aagggatatc tgtttctttt ggaagatggt tcgggatctt tttcactttc aatacatcta
     9001 aaaagaaggt aaagatcgga atgccgacaa tcaagcccca aacgccaaag aaccgttcgc
     9061 taacaagtaa gaccacaaat gtataaaaaa tcggcagttc tgttttgctg gacatcaact
     9121 tcggattcag cacataagac tcaattagat ggacaatcaa aatcgtaatc aggatataaa
     9181 caacatctcg gatgcctcct tgggaataag ctatgaaaga tagaggaata caagaaatga
     9241 taacacctgc tactgggatc agacttaaaa tgaaaatcat gatcgctaaa ctcagcagct
     9301 gatgaaagcc aaatacagcc aaggcgattg tagtgagcaa cgtatttaaa agagcgacaa
     9361 caaattgagc ttctaatacc aaaccaaatg tattgacaaa cttatcggca aaatagtaaa
     9421 tatcttgaaa gaaccaagaa aattcacttt ttaaaaacaa tcttgagaat acaattgttt
     9481 ttttcttttc aatcataaaa aagaaactta agatgaatga catagcaaac gccactgcca
     9541 tttttcctat atcctgtaaa tagccaagcg caatcgaagc gccattttga agctgttcaa
     9601 aaaaatcgtt tcgctcaata taagtatgga tatattgtaa aacaggatct gcatcttttg
     9661 gctgatgctc gtaaaaatta ataacggact ggatcatgtc aaatgtttga tgaataagca
     9721 tcgggatata ctttgtgaat gccagataga taaggtaaac gatcagtgta taaatcatga
     9781 tagctaaaac acctgtaggg attcggacaa atcgctgaat gatttgaaca agatgaatca
     9841 tcaaataagt aaagataaat gtgagcaaaa tggttgtaat catacttcta actaagaaaa
     9901 gaacaaaaac gacaaataat aaaacagtga gacggcgtat tttttcattc gccaaaaaac
     9961 gctgataaac ggtcaaatcg acaacctcca aataacaaaa aataaacacg ttattcatta
    10021 tatgatggaa tatgaaaata agaaagagca aaaagaaaaa ccgctaaatg acgttatctt
    10081 atgagttggt tttcctcata aaatcgttca tctagcagtt tcagcccttt ttctggtctt
    10141 gatgaaaatt atctagcatt tttcgggtca gatgttgcag tgtatccaat tcttcctgtt
    10201 caagtggaag ataagacttg atcttttgtg gaataccttc tgcttgtttt tgcaacgcag
    10261 caccttgagc agtcagcgta acatttacga ttctttcatc acccgtttca cgctgacgat
    10321 taatataatt tttttctgct aactttttta gtaagggagt cagcgtacca gaatccagac
    10381 acaaatcatt tcctagctct ttcactgaag tctttttctt ttcccataaa actaacatca
    10441 caagatactg ggtataggta agattcagcg gcttgaggag gggagtgtag tgtctaatga
    10501 tttctttaga ggcggcatat aaaggaaaac atacttgatt aactaaatat agatcttcca
    10561 tttttccacc tccgctgttt tactatagtg tatcatagcg gatttacaca aaaaagtcta
    10621 ttcactaact gctttcagag taacttctat atttccagct gtagcttttg aatacggaca
    10681 cactttatgc gctgcctcta ataattcttg cgtttcttcc agagaaagac cttcgataga
    10741 tccttcaatc tctacaccta agacaaagct cgtttcactt tctgaataaa gggaaacttg
    10801 tgcactgaca gtagaagccc cagagatatt tttttgctgt ttgatcaatt ctaatgcact
    10861 gttaaaacat gcactgaaac cagctgcaaa caattgttca gggttggttg cattttcgac
    10921 gcgtttacca ggagctgcaa tattcaattc gaatgtacga tcgggattat gcacttctcc
    10981 agagcgtccg cctgtgttga tcattttcgt agaatacatt tttttcataa agttaccacc
    11041 tttaattata ttttatacaa ttgaatttta cacaatataa ttgtggaaag caaagaaatg
    11101 gattggcata agataaataa gagaaagcac atgaaacaga cgcgctttct cgaatagcaa
    11161 acatatacaa aaaatatcag agacaaaaaa taatctcatc ataaacatta catatatttc
    11221 tcaaaaagtt gttttctttc ttcaaaaatt acttcacgat ggacctgatg aagcatccat
    11281 aaataaccaa aaggatctct gaacattgag ttagtcacac caaagtccat catttctgtc
    11341 atttcttgaa tctctacaca gccatttcgt aatgctttat tatgtgtgtc ctcgatatca
    11401 gagacgatga tattgaacca gatcgtattt ggatgttcag cagtaggagc agtcaaacca
    11461 agagacgtgt tttcatccag catatggaat ctcgtaccat acaaggtaaa aatgacttca
    11521 ttattgcctc tagggtaatc tgttgcctca atcagttgta tttcatcaaa gattgtttga
    11581 tacagttcta gtgctttcaa actatcattt aatacaaaat cgatttccgt tcctttatgc
    11641 ataaagatct cctctccttt tcagtcgaac agttactaga ttcttttatt ataccagcta
    11701 aagaaaacgc attcaaaaaa atagcggatt tacttaccaa ctcattcgat tggatgataa
    11761 gtaaatccgc gtcccattac ttctgctacg ctgctgacaa tgacaaaggc acttggatcg
    11821 atttcttcta tcaatggttt cattcgggaa aattcatgat cagtcacaac gatcaataaa
    11881 acctcttttg actttcgatt atacccgcct tttgcctcta gcagggtaag gccacgtcca
    11941 atctcagcac ttaagcgaag gcggatgtct tccaaataat gttcactcat gaccataaca
    12001 gatttctttc gattgatacc tgtttcgata taagtcatga caattgaagt gattgcaata
    12061 gataaaatag cataaagaaa ctcttctatt ccaaaaataa acagattaag agaaacaacg
    12121 aatgcgtctg taaaaaataa gccaatcgaa gtattcaagt ggaaatattt tttaaaaatg
    12181 aggggaggga tcgtcgtacc gccgctagaa gagttgtttt tatataaaat cgcaactcct
    12241 aaagcaaaaa tcgcacttcc aaaaatgaca gacaacaacc gatctgaagt aatcattgtt
    12301 tctggaacta ttgcaatgat taaaggaaaa accaagcttc cgaaaagtac tttaaaaaag
    12361 ggttttttac ctaaaaatag aagagctagt accaacataa cgatattcaa cactaaaata
    12421 actatagctc ggtcaaagcc taaagcagct tccagtaata ttcctagacc gctgacacct
    12481 ccagcagcaa tatgatgagg ccctaaaaac atattgatag cgactcctaa tatgaagagg
    12541 gcaaaaataa tcttaatgta tgtccatata aattgtctcg tttctttcat ttattcactt
    12601 ccttaattca ttaataatac tcttatctta
//
LOCUS       DADVXV010000082        12487 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.083, whole genome shotgun sequence.
ACCESSION   DADVXV010000082 DADVXV010000000
VERSION     DADVXV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.083"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(31..1383)
                     /gene="celB"
                     /locus_tag="KB969_002267"
     CDS             complement(31..1383)
                     /gene="celB"
                     /locus_tag="KB969_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBB6870227.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(1383..1901)
                     /locus_tag="KB969_002268"
     CDS             complement(1383..1901)
                     /locus_tag="KB969_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870228.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(1917..2243)
                     /locus_tag="KB969_002269"
     CDS             complement(1917..2243)
                     /locus_tag="KB969_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBB6870229.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(2256..4235)
                     /locus_tag="KB969_002270"
     CDS             complement(2256..4235)
                     /locus_tag="KB969_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBB6870230.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(4256..4570)
                     /locus_tag="KB969_002271"
     CDS             complement(4256..4570)
                     /locus_tag="KB969_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBB6870231.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4738..5031
                     /locus_tag="KB969_002272"
     CDS             4738..5031
                     /locus_tag="KB969_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBB6870232.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(5109..6221)
                     /locus_tag="KB969_002273"
     CDS             complement(5109..6221)
                     /locus_tag="KB969_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6870233.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            6608..6787
                     /locus_tag="KB969_002274"
     CDS             6608..6787
                     /locus_tag="KB969_002274"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870234.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            6981..7151
                     /locus_tag="KB969_002275"
     CDS             6981..7151
                     /locus_tag="KB969_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870235.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(7575..10975)
                     /locus_tag="KB969_002276"
                     /pseudo
     CDS             complement(7575..10975)
                     /locus_tag="KB969_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(11647..11915)
                     /locus_tag="KB969_002277"
                     /pseudo
     CDS             complement(11647..11915)
                     /locus_tag="KB969_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT         3756 a         2615 c         2012 g         4104 t
ORIGIN      
        1 tttttgtcac agttcctttt ttcttagaaa tcattttaac ttttcactag ctaattctgc
       61 tgccttttct ctttcttcat ttaataattt attatcatag aatttgataa atgggaacca
      121 gataatgaat gcgatgattg cacaaatgac tgctaacaca gcagctttcc aatcaccacc
      181 actaccaaca aatgctccga tcccgactgg tgaaggccac ggcatctgtg caagcatcgg
      241 tttgacgatt tccagccgaa tggcaaaata agcgagtgta gcagaagcca tcggagctaa
      301 gaaaaacgga accgctaaat agggattgta gacgattggc atcccgaaaa tgattggttc
      361 attgatattg aataatcctg gtacaagtga ggcttttcct aacactttca gctgatcaga
      421 tttcgcgagg aatgcaataa agatgatcaa tcctaaagtc gcacctgatc caccaacggt
      481 tacataagaa ttgttgaatt ctcctgccaa cggataattt gcgccttgtg cgttagctgc
      541 catattagct aatacgatcg gggtcaagaa agaagtgatg atattcgctc catggatccc
      601 tacgatccac aatgcatgga tcaagaaata aatcaccatg acaccaagcc atgtattcgt
      661 caactgcgta acaaacccaa atgggatagc aatcattttg aagatatccg ttcctagtgc
      721 aactaataat ccattgatga tcatcaccac aaacgcaatg acaaatgttg ggatcagagc
      781 agtgaaagaa cgagaaactc ctggcggaac aacatctggc atttttatga cccaatttct
      841 cttgacacac atacaataca attcgaccgc aataatcgac ataataatag ctgtaaagat
      901 tcctgaagtt cctaaacgtt cgacaaaaga gcccatccta ataccattta ctacagtttc
      961 tgtctcattg atagaagcaa tcaagctgat tttaccatca gtcatgatca attcagggat
     1021 acacataaag aatgcaaaaa cagatagtaa tgcccccgtg agcggattaa catttaattt
     1081 ttgttcatct cgttcaattg acgttaattc ataagcaaac acaatggcaa agtaaataga
     1141 taaaatcccc atcgtcattg tattgacgat catgtacaag tcactaactt tgaaaaaagt
     1201 tgcattaaaa aatccttcta aaaatgggaa cggtaatggc aaaatattta aaaccaaaaa
     1261 catcgagcct acaatcgtga aaggaataga agccatcccc gctgccatga cagcccgaac
     1321 gattttaagt tgcgcaattt tccccatagg tcccatcagg tatttctgca aaaaatcaaa
     1381 cattagttat tctcctttcc taaatataac gctttttcat attgtttaat acggatatac
     1441 tgttggtctt ggttgagtga aattttcttt aaacgatact gtataaatgc actggcaaaa
     1501 ataccgctta caacaagaat gaaaacaaat aactgtcctc cattgttatt tgccataaaa
     1561 ggatacaaga atgtaaatcc tgaggtaaac aacactggaa tcactaataa attaaagaca
     1621 ctctggaaca aaaaatacca ctttgtccat ggaacgttcg tttggtgttt tcgataaagc
     1681 tttacttgtt ctcctactgc aggcaaaata gctaaaatca gaatcatcgg taaactactt
     1741 cctaaacttt tagctgatag aagcagaatc atccattgca tgttcatgaa aaagaaaaag
     1801 gcagtcaggt aacgtacgat tagataacga ttgaaataca tgtttttcaa actaagttgc
     1861 tttttttcta attcgatttt cctttttact gtatcctgca caatgatcct tcctttctat
     1921 ttattttttt gatacaaata attcatttcc tgtgcaactt ccaataatgt catcgtcgtc
     1981 atcagatgat cttgtgcatg gaccatgata atttccattt ctatttttgt cccgctggca
     2041 tattctttca gaagttgagt ttgtgactga tgcgcatgaa gaatctcttc atttgcttgt
     2101 cgcaacttct cttctacttc ttcaaacatc tctttacgca tcgagcgaaa tgcttcatgt
     2161 atcagtgtcc gtgcatttcc gctatggaaa atgatatcaa aagaagtcac ttgtagtgtt
     2221 tcactgttta ttttttcagc catctgtttt cctccttatt cgatcagttt gataaattta
     2281 ctgctgaaat tctcaaaaat aggttcagct aagatttcct gctgtacttt tagctggtca
     2341 actaacctaa cgattgcttt agtcacgacc gtaattcctt cattttcgac ataagaaggc
     2401 gaaactaaaa aaacaaaatg aatttcttga tattgatccc actgcatccc agaaggaatc
     2461 aatgcaacgg ctacctttgt ttcgattcca actggaacag cgggatgtgg gactgccact
     2521 gtatcactga atatgatttg tcccatattt tcacgttgct ggatctgctt tcgcatttct
     2581 cttatatatc cttcttcttc atttatgctc agcttttgca gcaaatcatg aagaatttct
     2641 tcctttttcg gttcgtacgt ataagtcttg aaaaattttt cagacaactg ttcggtgtaa
     2701 atctgctttt tttgctgtag agaaaatgct ggtatcggtc tatctgagga atgatagggt
     2761 atagattctc caactacctt tcgtatttta cgaacatcat cttcattcaa aaaaatactg
     2821 acatgtaaaa ctggaatttt gaaaaacatt gtcgaaagat caatagaaga aataatcagg
     2881 tcgattcctt ttaaagttgt ttcattgatc tcataatagc cttttacact taccactgta
     2941 atatttttac cgaattcact gactacgcga ttctttaata gttgggcact gccgtaaccc
     3001 gttgcacaga taatcaatgc atgtagttta tgcgcagctc tttctttttc caatgccgcc
     3061 atgagatgca aagccaaata ggcccattca tcttcattga tggtatagtt tttcaaagcc
     3121 ggcatgttgc tgaaatgcct ttttactgcg tcaaagactt tgggattttc tttctttatc
     3181 tcctcagtca atgggttctc aatgcgaata cctcggctca atcgaatcat catcggtgac
     3241 aaatgatcga gtagtccatt gaaaagctgg agatcctcta ctaatgaaaa atgaaattcc
     3301 tgagacaatc ttttcagaac tttcgctaat tcctttgata gttcctgatc attttgattt
     3361 tctttgtgat tcgacttagc catgagatgt aatgtcaaat aagcaatttc ttcttcggga
     3421 aacgatacac ctgcgattac ctcaatacgt tgaacgatcc gctgcgccac ttgatactct
     3481 actcgcttag aaacttcttg ttcgatgcct aattccttga tttcaaaccc ttctcggagc
     3541 cgtttgatcc ccaaagccaa gtgtaaagtc agattctgta tgataaaatc cgaaactttt
     3601 aacttagctt ctcttgtttc atcgagaatg ataatgacta gctcttcaaa actgatgtct
     3661 gggaaaaaac ggctttgccc taaatattct ttcaatgaat ttccataatg gtttccaaaa
     3721 aaagtatcca tgataaaatg ccgtcgattt ctttcttccc cttcgatcca tgtcccttga
     3781 ccatgcttag aaacgatttt tagtgaatat ggaatcaatc gctccttgat ttcttgcatg
     3841 tcctttgtca aactggaacg actgatataa agctcttctg ccaaatcatc cataaaaaga
     3901 atggcatctt ccaaaagcaa ttggttcaat atatactttt gtcgatcttc ggactcataa
     3961 aatccttgcg gttctctagc atatccaggt actatttctt gccgactcaa aaacaagtca
     4021 aatgtcagtc tttgtaaaat atgcagttgg tagccataac ctggtttagc aatgatctta
     4081 cctccgtttt tttctactaa ctctttgatc cgctgcaagt aattacggat tgtccgatca
     4141 gataataaca attcagaagc taaacgttga ctggtgacat actccttctt gtgatcaatc
     4201 aaatatctca acagcaattt ttccttctgt ttcattatca tccactccta ttccatcata
     4261 tgttctcttc gatcacctct gctaacttct ggatgcctgt agggattggg acatacgctt
     4321 ggaaagggat actaacaaca ggctttccaa cagattctcc taattttttg aatttatcca
     4381 aaaacatcgt cgtttgcggg ctgatcagaa ataaatcaaa atcactattc ttaatcatat
     4441 tatcgccttc tgtagctgaa actgcatcta cgagtacctc ttctcttttt tgcttaaaga
     4501 aatccgttgt ctttgaggcc atcatcgagg atgacattcc tgccgcacaa ataatcaatg
     4561 cttttttcat aaatcaatca ctccttttat ttttataaac caagcatatc ttgtaagcgt
     4621 tttctattca aaatatatat ttccgtagca ttgcggaaaa aatgtgtatc atatcttgaa
     4681 taataatttc tggcaccgtg atatactagt gatagaattt tttcaggagg ggatttagtg
     4741 agtatcacag tgaatatttt gtatacaagt acaaatggac aagccagaaa atttgcagaa
     4801 gaaatggtcg aaagaaacat tgtcaaagcg attcgtgcag aagaaggaaa cgagaaatat
     4861 gactattact ttccactaga agatccagaa tctcttttac tgatcgaccg ttggaaagat
     4921 gaagaagcaa tcgaaaagca tcacaaatcc gaaatgatgg ctcaaataaa cgaactccgt
     4981 aaaaagtata aattaaaaat gaaagtcgaa cgtttcactg atttaccgta aaaagataca
     5041 catggaatga tagcaattta tcatccatgt gtatcttcac tttttcctta ttttttattc
     5101 gatctcatct aatgattcaa accgtgtttt tctcttattt ttcggataag tatttcagtc
     5161 accccaatat acatgattcc taaacatacc ccaaggatat tctcaaaaat gcggatcgtt
     5221 actgctcctg gaaccccgaa taaactggca gtgattgcca aagcaccaaa agaattaaaa
     5281 actgttttat atctataggt agaacaaaca cctaaagcta gaccacctaa tataccgacc
     5341 cagttaaaag gaataaattg gctgatacca ataaataaaa cacatccaat caatgagcca
     5401 atgattcggt ctactgctcg ttctttgaaa ccaatcgaca tcaatccata gctagataca
     5461 atagaagaaa atgcaaaccc tgcccacatc aatcgctgaa aagggacata ctctcctgca
     5521 acgatcaaaa gactaatgcc aaatgcatag atgagcatcc aaattttttc ctgcgaatac
     5581 atgcctttca aaaaaatctc tttaaacaag cttttgtctt tgttcttttc tcgatgtttt
     5641 ctgtaaagga gaactgaaaa ccaacaaaaa aacaaaaata ataagctact tgtttgtgta
     5701 aagaaattct tgttcaacga atctttaggt aacgaataaa caataaagag atatgaaaag
     5761 ccgtacaaag aagcattccc cattttggga tcactagcgg ttgccattaa tatgctgctt
     5821 agtaaaataa aatgaatcaa catgcccata actgaccatt tgatcagctg gacatacggt
     5881 gctactaata gtgagaacat gacgattgct aaacctatga tcgaatggga aatcttataa
     5941 ccaaagtcaa caaaacgaat actcatcaac atacagaata aaaccacagc gtatggttta
     6001 tgcttcgatt caaataatgt tgtaattata atgataaaac aaatggcaaa caatacgatg
     6061 aataatgatc gtaaaaacaa tgaacaaata tacatgcact tttctttttt agaagctgct
     6121 tctcgtattt tttgttttaa aataaacgga tctagttgta gagactgata aaaatccacc
     6181 tgttgtcgtc ctttcttttt acttttattt tttacagtca tctatgacag gttgtaaata
     6241 ctatggaaca tcatatggcg ttgtcatttt cttgtcaact atttttccta ttcatgtttt
     6301 tataaaaaaa catatcgttt tcttgtatga ttaaatcacc acaaaataaa caactgagag
     6361 aacgatatgc tttatgaatg gttctatcaa aaaaattctg agatcaatag acaaaaattt
     6421 gatgattaca gaggtctctt acgaaacctt acagaagaaa aaaacattga tcgttgctgc
     6481 agttctcttc cctgctccat gtgtctgtag aaattgtggt tctgctgtgg tagatggaaa
     6541 taggaaatta atggtggtga aaaacaagaa gaaggaaacc attgtccact ttgaataata
     6601 taatcatatg ccaatggtta tacgcctaaa aaagcagcgc tatacctgta aaaactgtcg
     6661 aagccattgg aacgctcaaa gttattttat ccgtccaagg cactcgattt caaatcatgt
     6721 cagacataaa atcacttctt tactgactga aaaagtgtcg ttatttttta tttcgaaaag
     6781 ttgttaggta tctttgacaa ccgttattcg cacattgaaa gagttgagaa gctatttacc
     6841 aaagtcttcc aaaagaattc tgtcttgagt gttgagggtt gtgaatttcg ttctcacgtt
     6901 tccgttgagg ataaactgag ttttatttcc gcggatggcg agacagaaaa attaatcgag
     6961 aaaatttacc tacacaaaaa attcctcgat taacaaacta tttccttagc tgcactaatc
     7021 ctaaagaaat agaattctta gttacagaca tgaacgccac ctactttcag ctcaccaaac
     7081 atgttctacc aaatgcgaaa ttggtgattg atcgattact tggtttttcc acgcctttca
     7141 aggaggcgta acctttattc acgagttggt tgaagctttc cgagacaaaa gacccgactt
     7201 gtttttctcc ttattgacaa agagccatta aaactagaga aaaaattaca actgatcgct
     7261 gattatttgt agaaagaaaa tcaaagtatt acccaataaa cttgagtcat taggcaaaaa
     7321 acactgcgaa actcaagaat gattttcgca gtgtttttgt atatttttta ttaactagta
     7381 ttactacaaa ggtttatttt tcacttctca acgcagcaca aaattgtctt tacttattta
     7441 ctggttgggt tcaaccttct ctactccgat actaatattt gtttgtatac cccttctaaa
     7501 atcggtagtt tccattcaat tgatgggtac tagttgattt taaaaactat gcttattcaa
     7561 ttttttattt tagctcatat atttcgtttc tttctaaatt ttatactgat gaaaacaagt
     7621 agcacaccca atattgacaa tataaactgg ctaatgatgg tttctccagt ttttggaaga
     7681 tgcttatttc cactgcttgt tggattgttt cctcttatat ctgagctatc agcaactttt
     7741 ctattctctt ttgttaaaaa gatcgccact tcttgttctt tttcgatctt gaaagttact
     7801 ggtgtcgcat ccaattcata ccctattggc gcttgagttt ctaccagctg atatgctcct
     7861 ggtgctaaac cgtcaattgc cagttttcca tcttctcctg tagttagacc ggtttgtagc
     7921 gtttctcctt ctcggttctg taactcaaaa acagctcctg caggatttcc ccgctttggt
     7981 catcgatctt tgtcaacacg acaccgcctg gtgtaagtcg gttttctttc gttaattcta
     8041 ccaccgctgt ctgacttctt tcgatctcaa actcgattgg tgtcgcatct aattcatacc
     8101 ctattggcgc ttgagtttct accagctgat atgctcctgg tgctaaaccg tcaattgcca
     8161 gttttccatc ttctcctgta gttagaccgg tttgtagcgt ttctccttct cggttctgta
     8221 actcaaaaac agctccttgc aggatttccc cgctttggtc atcgatcttt gtcaacacga
     8281 caccgcctgg tgtaagtcgg ttttctttcg tcaattctac caccgctgtc tgacttcttt
     8341 cgatctcaaa ctcgattggt gtcgcatcta attcataccc tattggcgct tgggtttcta
     8401 ccagctgata tgttcctggt gctaaaccgt caattgccag ttttccatct tctcctgtag
     8461 ttagaccggt ttgtagcgtt tctccttctc ggttctgtaa ctcaaaaaca gctccttgca
     8521 ggatttcccc gctttggtca tcgatctttg tcaacacgac accgcctggt gtaagtcggt
     8581 tttctttcgt caattctacc accgctgtct gacttctttc gatctcaaac tcgattggtg
     8641 tcgcatctaa ttcataccct attggcgctt gagtttctac cagctgatat gctcctggtg
     8701 ctaaaccgtc aattgccagt tttccatctt ctcctgtagt taaaccggtt tgtagcgttt
     8761 ctccttctcg gttctgtaac tcaaaaacag ctccttgaag gacttcacca ctgccttcag
     8821 catgtttaat tagttcaaca ccacccgtat caaggatgtt ttcaatggtt aacgtcactt
     8881 cttctatgga gtattcattt ataaaaacat catgtaccgt cgcatctaaa agataccctt
     8941 ccggtgcttc tgtttctcgg acttgatagc tacctacagg aagcggttca cttaaaaatt
     9001 ctccgttttc tgccgttata ccttcttgta tcacttgtga atcgcttgat aaaatttcaa
     9061 attttgctcc tgccagcctt tggccattct catcagtttt aattacttta atacgcccat
     9121 cgattttcct tgttcttaca gtactcgtat tcaatcgatt gtcactattc acaagcgttg
     9181 caaagtttaa aatttgatcg ccgaccgcat acgcctctac attgacctta aaagagaggg
     9241 taaaacttgt cggaccacca atcgtattat tcgcactgaa acgaactatt ccattattga
     9301 cttcggcatc aatgaaagag ggaatatctg atagaaatga cacaaattcc atgccttctt
     9361 ccaaaacatc ttcaataaca agcgtatttc ttgttccaga aaacatcgag acatgcagag
     9421 tatacgttag ttcattttca ttgagattga taacattttt gtccacactt tttcttaaag
     9481 agattgccgg aagattactt tcagggattc tcaagcggta gtctcggctc attacctgat
     9541 tattgtaggt catactcgct cgattccgag aaaacccatc ctcttgtctt ccttcattga
     9601 acaagtcgac atcggtcact tcaagagcat attcaataaa atacgattga ccctctgcta
     9661 gattaccaaa gtccacaaca agtgtattcg tttccttatt aaaagatact ttgtccacaa
     9721 attcctcgga aacataatga gttctaacgt ttgcttcacc tggattcgtt acttctgcga
     9781 tccgaacccc acctgaaata ggttctctat ttccagtgga actccatgta gtcggattcg
     9841 gtgccaaagt tgttccttgc ggtagtacat cggtaaccac tacaccgtct tttcgtgatc
     9901 cttcataatt tacctgcaaa ataaatttat tactgttggt cacgtcttgc ccgtcaatca
     9961 gcagattccc aagatttcct tggctgtcga tttctctaga gccatagtat aatttcgaaa
    10021 aaatgggtct tgatgaagga ataggcgtaa ttgaaaattc cgtgtttgct gctcgctcag
    10081 cataagtaag actcacttga aagtcattat ttggctcagt accgcctgat tgaaagaaag
    10141 caacttcaaa cgtgatactg aatgtatacg actgagcggc ttcatttaat ccttcataat
    10201 caaaggtaaa tggaaaaaca acgtctgtgc cttcttggta aaatgccagt ggctttaaag
    10261 gtgaatcatc agcgacctcc actctaatga actcaattaa gccaatcgat gctctaggaa
    10321 ctcgtacgac catctcccca tattcttcaa gaatatcgcc agcgcctcct tgaatgtatc
    10381 cctttaacgt ttgtgtatgc ctgctcggca aagtggggcg ctcagcagag atgccgatgt
    10441 cataattcaa gagctcctct tgtctttcaa tctgagattc ctgcgttata gatggctcag
    10501 atgatctggc ttcattaaaa gattcactta agctttcttc tggtatatta aaagattcac
    10561 ttgtgctttc ttctggtaca ttaaaagact cacttgtgct ttcttctggt acactgattt
    10621 ctattgagac cgtatttgat tgaatatcac cgcttcttgc ggtcaattcg tatttacctg
    10681 aatgctggga agaataagta atcagacgtt cgtaatcatt gagttgcttc acttcccctt
    10741 caatcaaatc ctcactctta tcaatgacca atgcatttag caggtctggt gttcctctga
    10801 ctcgcaactg gaactgctca cccaaagcag cctcctcttg atcaacttcg atcgtcagcg
    10861 aacgctctgg ctgttctgct aaagactcag ctagaaccgt tatgttccca aattgattga
    10921 tcacaataag cataactaga aacatactta acagtttatg aaatttgttc ctcactatta
    10981 ctccccctta taattttgac taaacaacaa ggtacccgat aattttctaa aaagattccc
    11041 caactcaaaa tggctgcgtt acctccctcg tattttcggt tcaactcaag cgttgcaatg
    11101 taagctgtaa acaaagctaa tgattgccga ttgtcttctg ttgattgatt cgatagcttt
    11161 gtatgacttt tagttgtccg tgtggcttaa ccataattat gatttcacga ttcctcctgc
    11221 cagtgccttg cacaagctgg agcgtaaccc taatagttat tttgttaatg tacttatata
    11281 cttttatact tttccattag aaacaatcac taaatcgttg ataccaaggt cagactctag
    11341 aatttcatca gtgagtccct gtattggtta accttcatca atcccaaaaa aatatatcaa
    11401 tgcttagcat caaaatgaat atatagttta gaatacttgg gattcatcga taactgatcg
    11461 cttatttggc catattattt ggcacttggt tcaactaaac gcatttagga tgttccttca
    11521 ttctcgtcat ggatgttctc aaaccgtcat tactaataaa ctgtccaccg aatcgatggt
    11581 tcatttcttg cattttccac gtccaattac tctttttgct ctttatttgg gcgtagtttc
    11641 actttcttaa cttgtatcgt cttccatcaa ctccttaatc atcttcttag ctttattggc
    11701 tcggtttcct tgtaaaaggt atctacaaat agtgacaatc tgtattaaat cttcatcatt
    11761 ttctgtaatg tcaataattt ctatattctg taccatatat tgcaaagggt ttcactaagt
    11821 tcataaccga agcgaattaa acaacttttg tatagaataa ctaccttttc tatttttcca
    11881 ttggtaattc tatctattaa ttggtttaat ccttttgttg tagttgattc cactaccaag
    11941 atgattctct cgaattttaa agcttgaaga tgtattgcta tttttgctaa ctggcgtatt
    12001 tgcaactatt tttcccttct attcttcctt cattgattcc cctctaaaat tactatccat
    12061 aaaaaattgc ataaatgaca atagtattta tattagtcat actgcttttt aacacagcaa
    12121 attccagaaa aacattcgtt acatatttgt gaatttttcc aaaaaataac atttttataa
    12181 aacgacgaaa aataaatcac taccagtcaa cttctataat attaccaaat aacaaactaa
    12241 ctatccatca ataacgtgtt ttatttttta aaatttctat aaaaaaacaa tcattcttaa
    12301 aaagaatata taaaaataac aataaccttt gtgatttttc ttgtttgaag aatgttagaa
    12361 gaaaaatctc taaatactta taattatttt ataagcaaaa aaatgctatc ggtagtatca
    12421 ccgatagctg aggaaagtca cagtagggac tatttgatta aaaaatatgt ttattcaatc
    12481 catctat
//
LOCUS       DADVXV010000083        12396 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.084, whole genome shotgun sequence.
ACCESSION   DADVXV010000083 DADVXV010000000
VERSION     DADVXV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.084"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(130..777)
                     /locus_tag="KB969_002278"
     CDS             complement(130..777)
                     /locus_tag="KB969_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBB6870236.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1056..1559)
                     /locus_tag="KB969_002279"
     CDS             complement(1056..1559)
                     /locus_tag="KB969_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6870237.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1682..2446)
                     /locus_tag="KB969_002280"
     CDS             complement(1682..2446)
                     /locus_tag="KB969_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBB6870238.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2553..2828
                     /locus_tag="KB969_002281"
     CDS             2553..2828
                     /locus_tag="KB969_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBB6870239.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3505..4455
                     /gene="yidC"
                     /locus_tag="KB969_002282"
     CDS             3505..4455
                     /gene="yidC"
                     /locus_tag="KB969_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBB6870240.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="KB969_002283"
     CDS             complement(4634..5608)
                     /gene="lacD"
                     /locus_tag="KB969_002283"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBB6870241.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5605..6063)
                     /locus_tag="KB969_002284"
     CDS             complement(5605..6063)
                     /locus_tag="KB969_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6870242.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6060..7523)
                     /locus_tag="KB969_002285"
     CDS             complement(6060..7523)
                     /locus_tag="KB969_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6870243.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="KB969_002286"
     CDS             complement(7505..8455)
                     /gene="pfkB"
                     /locus_tag="KB969_002286"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6870244.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8598..9347
                     /locus_tag="KB969_002287"
     CDS             8598..9347
                     /locus_tag="KB969_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6870245.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            9614..11092
                     /locus_tag="KB969_002288"
     CDS             9614..11092
                     /locus_tag="KB969_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HBB6870246.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(11160..12251)
                     /locus_tag="KB969_002289"
     CDS             complement(11160..12251)
                     /locus_tag="KB969_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBB6870247.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         3859 a         2516 c         2101 g         3920 t
ORIGIN      
        1 aaagaaaggg gctatcccca gactttagta ggcgtcatta gctatctttc gttagcattt
       61 aaaggcgaac accatcacct attcacttcc attaaaagat agcatatttt tctgtaaaaa
      121 acaataaaat tatcgttctt tctttacacg ttcagcaaat tcatagaaag gagccaattt
      181 cgttaactgt tgattacatt ggtcactatc atgacaaata taattcccct ttttcgtata
      241 cgtgccatca gaacctgctt tcgttgtaga aagaaaaagc gacacattcg atgttttctg
      301 acagattgca cagattccct tatttatcgt tggtgataaa gtaccgctaa tcccttttaa
      361 tttttcatct tcgtaataga ccatgaattt tttctgcgta cctggatcat tccagccgat
      421 gtacgtatgt tcttgcaagt cgatttcatt ccaagctggt tgtttgagtt ttttcacttt
      481 tcggaataat ttctcgattt gtggtttgct aggctgcata aacggctgga cgatttgctt
      541 cagctcctcc aatgctcttt ctgcttgcgc ttttgtcagt tttacgtcta aaactgtcgt
      601 taaaaatgta tcgatttctg gcagttcgtg ttctaatatg tctcgaatct tttcagctgc
      661 tagtgcctga actgtttgta ccgtttttgg atcattgaca gatgagtacg catttaataa
      721 ctgatctact tctcttttta taaaaaaata ttggtatggt tttattgttt gttccatgat
      781 tttaaagtcc tttcttctaa ccaaagtgca tactttgtag aaaaaagtga tcttctgcaa
      841 agtatgtgtt acctgaagat cccggactct tttaaataag atacgttttg catcttatca
      901 tcaccccctt taatgttcat tcttctatgt acatgattca ttcgataaat aaaagtaaac
      961 cgtatcttga acagatagtc aactgcaaac agaaaaaacc gagaaaatca gccagatttt
     1021 ctcggaatat agtctattat tattggtttt acctattaaa tcgaggattc tttcccaaag
     1081 taacgttgcc atctcttacg catacttgca gacatgggct gagccgcttc tttgactgcg
     1141 cagtatttgt ccacgaatgt cacaatatat ccttctttat acttaggcgg tgcgatcgtt
     1201 gcaccccaca tgtgcttcaa aatgatatct cgctcaagat ccgacaaatc ggtgattttt
     1261 tctgcattct ttacagcaat tcttggatgg atatacgcat gtgtcccctc gtcaaatttc
     1321 gtcgtacgcc aatcatagta gaacagatca tgcaaaagtc cagcacgcgc tgttgcttta
     1381 gcattgccac cccatttttt tgcgagcaga taactatagt aagaaacact gatggaatgc
     1441 tccaaacgag tggaatgaac atgctgtgtg taattcgcta attttttcac tgcttctgtt
     1501 tctaaaagat cttgtacata agacatatat tcttcgtctt cacgccattt ttctgtcata
     1561 attatcgatc tgccaccttt ttgaatttca ttttcttctg aaattgatct aagtatacca
     1621 ccagtgttcg gattattcta gtcgctctag ataaaatagc taaagcttaa tagttcctta
     1681 atcataaaga aaaatgataa agaacgatcc ctgctgcgac tccgacattc aatgattccg
     1741 catttccttt cattgggata tatacgttct gatcagtcaa agacaagatt tcctgactta
     1801 ctccctgacc ttcgtttccc atgattatag cgaaatcctc tgttttttct actttgtcta
     1861 atgcatgtgc ttcttcattt aattctgtac cgtacaccgt aaaccctttg cctttcatta
     1921 cagggattac atctgccaaa tctttttgta acacaggcaa atgataattg cttccctgca
     1981 tgcttcgcag cacctttgta ctataaatat ctgccgttcc tttacctaat aaaacaccag
     2041 ccataccaaa cgcatctgcc gtacggatca tcgttcccac atttccagga tcctgtacat
     2101 tatctagtaa aagccagcct cctgaaaaat ctggcgtatc ttcagatgtt aacgtcatca
     2161 ctgctaagat cccttgcggt gtaggtagat ctgacatagc ggtcatgacc tcatctgaaa
     2221 ctagaaaagt agaaatctct ttgtttacag ccagccagtc tccccattct ttcatacctc
     2281 tctgtgtcac aaaaagttct tttatttctg cattagacga cgcagcttct tcgatcagat
     2341 ggaacccttc caaaagatat tctgcctttt cttctctgta tttcttttta tgtagttttt
     2401 ttaattcttt gattcttgga ttttttgctg attggatctc tttcacattc ctcacctcaa
     2461 ctgattatat catggaatag gtgcttgagc ttgtttcatc ctaaaaaaat cggtatcatt
     2521 gatttataaa acaggaaaga aaggtgacga acatgcgcaa agttaaaatg aatgtccaag
     2581 gacgtgtcca gggcgtggga tttcgctata tgaccaagat ggttgctgat cagttaggcg
     2641 tgaccggaac ggtaaaaaac gaagacgacg gctcagtcac aatcgaagca atcggaaatg
     2701 acgacatcat ccaaaaattt atcgaagaag tcaagaagtc tccgagccca agtggacgag
     2761 tgcagtatgt ggatgtccaa gaagatccga tgattgagga acgaaagaaa tttgatgtag
     2821 tgggataagg ttgtgaaaag gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2881 ggctttccac atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg
     2941 tcgataaggt tgtttttgaa gcgctttgcc tcgagtatta aggagaaaca ttttcaaaat
     3001 agcttctcat attttgaaat gtaatgactt aataccgaga ggcagctgat aaaacaccgt
     3061 caataaggtt gtgaaaaagc tggtctgcat caagcattaa ggactggttg tgataaatag
     3121 ctctccatat ttttcaacag gctggactta atgccgtaga tgcaagcttt tgaacaccgt
     3181 cgataaggtt gtttttgagg cgctttgcct caagtattaa agacaggtag taaaaaagct
     3241 gatctataac ttgcaatgaa tttgcttaac ccatattttc cagacagaac aaaaaagttt
     3301 ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta agtatttctt
     3361 tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa tatttatatg
     3421 aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa gtttgtgtaa
     3481 aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt gggatccgga
     3541 cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa cggaaaccct
     3601 gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc gattacatat
     3661 ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac tgtgatcgtt
     3721 cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat ccaatctgaa
     3781 aaaatgcaag cgttaaaacc acaagttgaa gcagcacagc aaaagctaaa agctgcaaca
     3841 acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg cgaaaatgga
     3901 ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc gatcttctct
     3961 gccttgtatt ttacggcacg ctacacagaa ggtatccggg aatcatcttt ttacggcatc
     4021 gatctaggct caccaagtat ggtgcttgtg gccatcgcag gggtcgctta tctgcttcaa
     4081 ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg tacgatgctg
     4141 atcgtctctc ctgctatgat cgtcttcatg tcaatcagtg cgccagccgg tgttacactt
     4201 tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa cgttatgatg
     4261 aaaccacgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc aaaacaagtc
     4321 gtcactccaa gaaaagacgt gacagaatca gcaaagccag ctaacaacaa acaagcaaca
     4381 aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc aggaaagcag
     4441 cagaagcgga agtagatagt aaataagagt gtaataaaaa ttcattaaca gttttagcaa
     4501 ttaaaaatat cgaccaagat ttttgaaaaa gaaatctggt cgatattttt atttaagtga
     4561 atgtttaatt tgaatcatcg attgatcgct atctaattgc agcagcatct ttttatgaag
     4621 aaacaacttt ttcttatcta tcaacgtaga caggtgttgc tgtttcttct aatagtgtac
     4681 ttaattcttt aatattttgt tttccttctt ctaacatcca actactcgct ttttcttcgc
     4741 cttcggtaac aaaaggtgcc actcccttcg cccatgttgc tcgcccacat aagacaccat
     4801 tgaatgtcga acctgattgt tttgcaaaac gtaatgtatc ttgaaatagc gtagcattga
     4861 ctcccgcact taaaaaaata aacggttgtt cagtcacttt cgattgttca tagaaatacg
     4921 cggatgcctc tgcttgacta taacaagtct cttgcccata tccttccaca aatctcatat
     4981 tcactggcac ttctactttc aatacatcca cttgataacg ttcttttgaa aattctcgca
     5041 tggcttcaat aactttatgt ggttttactt ttgcataggc aagagaagac ggatcgccaa
     5101 tagttgcatc ataagaaaga atctctaaaa agaaaggtat gccttctgct tcgcattctg
     5161 aaccaatccg ttctataact atttgttttt gcacattaat ctctgctggt tcatcaacgt
     5221 catagtacaa taaaaattta caagcatccg caccagcttc ttttaacctt ttcaccgacc
     5281 aaatattcaa taaatcaggt aatcttcccg gtattttcgt atcatagccg gttttttcat
     5341 aagctagcag taagccacat tctttctctc gaagcgctgc tgcaggcagg ccgtattctg
     5401 gatcaagtaa aatagctgag gcatagggag tcaggtattg agaaaccatc tgtttaaatt
     5461 ggatgatgtc ttctgatgta gcttctttat attggttgat cattttcttc aaagcaccac
     5521 gctggtcgat tgctaatgcg ctaataattc cagcttcatc cgtcaatcgc ttcaaacgtt
     5581 cctgtttttc tatactcatc ttcttcatag atcttcacct atttctttag ttaatattgt
     5641 ggctatttct gtttttgatt ttgcttttct caactgttct gtaacctctt ttcgcatcaa
     5701 tgatcgtgca acgagagaca ataatttcaa atgagtcgtt cctgcttctg aatctggaat
     5761 aaataacgca aaaataaaat caactgactg tctatctaaa ctgttccatt caattccttt
     5821 gttcagtgtg gcgataatca tactaggttc gttgattgtt tgagacttcg catgagggat
     5881 agcaaaacct gacattattc ctgtagtccc ttctttttct ctttctagaa gtttttgata
     5941 tacttctttt tcgtcaagag cgatccctaa acagaatgtt tgctttgcta aaaacttaaa
     6001 tgcttcttct tgactatcca atggctgttg taaaaaaatg ttctcttcat gaatgattgt
     6061 catgataagt ctcctgctct tcctttttcg ataactgtac gatttgctgc tttattatcc
     6121 atcttcttgt ctttatcagt tactcttttc ttttggatta atcctagtat cactccacca
     6181 acgatcgaac caataagaat cgctgtaacc cattggattt ttcccgtcac tacaggtaac
     6241 actaaaaaac caccatgtgg tgctggaact tggacgccaa acaaataagt taagacagca
     6301 gcaattgatg agcctaacat catcgtgggt aacactcgga tcgggtcttt cgcagcaaac
     6361 ggaatagctc cttccgtaat atgagttgat cctaaaataa aattaaccaa acctgcatta
     6421 cgatcattgg tatcaaaata tttaccaaac aataaagtag caaaaccagt aatcaacggt
     6481 ggtgcaatac aagctgctga cacaccagcc ataaaagtcg tgtttccttg tgccaaaaga
     6541 gctgttcctg ttacatatgc cgccttatta accggtcctc ccatatcaaa cgcacacata
     6601 cagccaacaa tcacgccaag aacaagtgga ttcgaatgtt caaatccagc taaaaagctc
     6661 atcattcctt catttatagc cttcattgga cctgccagca aagacatcac gatgccaata
     6721 aatgctacac caataactgg atataagaag attgccttca agccatctag ttgtttaggt
     6781 aaaattgtca gtagcttttg caaaaataag ataaaataac ctgctaagaa cccagctaaa
     6841 atacctccta aaaatccagt accgccattc atggctacga ttccaccaac aaatccaacg
     6901 actaaccctg gacgtttcgc gatcccttct gcaatataag ctgctaaaac tggaaccatc
     6961 attcccattg ctgcatcgcc aactgctttt accattgccg ctgtagcatt gtattgtgca
     7021 tgatctggat caaaagaata gattccccaa acggcaaatg aaatagcaat caatactccg
     7081 ccagctacca cgaaaggcaa catatgagag acaccgttca ttaaattttt atagatgcta
     7141 cgaccaaaat tagcaccact catcgcttct ggttctaaag tatcagcagc ttcattatct
     7201 gctaagacag taccttttcc tgccaatgct tcgtcaatca gccgttgtgc atccttgatt
     7261 cctgtactga cagaaacatc aatgactcgt tttcccgcaa atctttctga atggacatct
     7321 ttatctgcgg caataatgac agcatctgcc tgtttgattt cttcagccgt taattcattt
     7381 tcgatcccaa tttgtccatg ggtctccact ttgatcttga tgcctttttt cctagctgct
     7441 tgttctaatg cctcttgcgc catgtaagta tgcgcaattc ctgtcggaca accggttgct
     7501 gcaattagtt gatattttcc catgtttcaa acctctcttc cttgattttg atttgtttac
     7561 ttaattcctc cacatccaaa aaatcagtca gtcctttacg aaaagcggtt gagctgcctg
     7621 ctgctatgct tttacgtaac gtttcatcaa gcggtcgtcg attcatatat cctgctaaaa
     7681 aagcgcctaa catggtatca cctgcacatg ctgtattgac aacttttcct tttggcgagt
     7741 ttcctcgaaa caccctgtct ttcgtaaaaa gaatcgctcc tttctcaccg agggataaca
     7801 aaacattttc tgcacctaac tctactagtc gttgtccata aacaaagtaa tcttcatctg
     7861 taaccatttt tcgtccgaac caagaagaaa gttcttcctc gttcggtttc agcaaaaacg
     7921 gtcgataggg taaacaatcc atggcttctt gatcactact atcaataatc aaatgaatcc
     7981 ccttttcctg acaaatccga ctgatttcta ttaaaacctt tggagacagc cctcttggta
     8041 aactcccaga aacacaaaga taatcttctg cttgtaatgc tcttatttga tttaaaaaat
     8101 tatggacagc tgtctgcggt attttaggtc cttgattcac taatttgtat tcttctcccg
     8161 tttgattgac ttgtgtaaat acattgatac gcgtcatacc aggcacttca ataaactctg
     8221 tttggatttg tttctgctgt aaatagtctt ctatatactt tcctgtaaac ccagcagaaa
     8281 aacctaatgc cgtacttggg aaatctagca tttttaatac tagtgacaca ttcacccctt
     8341 ttccgtttgc ctgaatgtca tcctcttttg tgcggtttac cataaaagga tgcatctcct
     8401 ctgtttcaat aaatagatca attgccaaat tcatcgtgca tgtgtagata gacataacca
     8461 acgacctcct tgactctatt atgaaatacg cgaaagagaa aatgttttct taatcgtccc
     8521 aacacaaaga aaacctttac atttataaac tcgtcgtgct attttttaac taacttttgg
     8581 tgaaagaagg aaagaatatg gatcacaaat taagtgaaac agaacagtac ctctggaact
     8641 ttatcgaaca ccacatccta gagatcccta actactccat cgtgaaacta agtgaacaag
     8701 caaatgtctc aacagccacc attgtgcgga caatgaaaaa gaaaggctat gaaggattta
     8761 cttcgtttaa gcaccatcta aaagaaggag aaaacaagaa catcaatttt tctttcttag
     8821 ataaagtaga caaaggtatc cgtcgagcca ttctaaaaaa tgaacaagaa gtggtacgta
     8881 cgatcaatat gttggaaatc ggaaatattg aggatgcaat acaaagaatc aaatttgctg
     8941 accgggtttt tgtctttgca cgaggatttt cagaaatgat tggtcaagag atgctcgtaa
     9001 aacttcaatt aacagggaaa aattgtcaaa tgcatactga tccagaaatc atcaaaagca
     9061 tcagtcggaa actaactaag aaagacagcg ttatttttgt ttctttgaac ggcgagacaa
     9121 aagaactcgt caccgccgca aagaattgct atgatgcaga gattggttcg attctagtta
     9181 cagccaatca ttcctctaca ctgaaagact attgcgagat caatctcgta ggtttcaaat
     9241 cagaaggttc ttatttccct gattatgaag tacggtcacg tttgcctctc cagattatag
     9301 cgagaatcct gcttgacgcc tatgtattgc gtatggggga gaattgaaaa gcagtttatt
     9361 atggttggtt acagtttaaa acatcacatt ttttattctt tatattgtat ggactcacgg
     9421 aaacttttta tgtataaagt tattcacaat ctataaagtt actttaaata acaaaaaaat
     9481 aattgaaaat acttaaaatc aaaaaatatc tttttaatca ataaaaaaat tgacagtttt
     9541 attaataata agctattctg ttatagaaga aaaaattgtt tgttattatt agcaacaaaa
     9601 aaaggagtgc atcatgaaaa agttatctca aaaacgttta gctcaaatca ttattgattc
     9661 tagaaaatct ctgaaaatga cacaacaaca acttgcagta gctactggta tcaaccgtgc
     9721 cttaattagt cgattagaat ctctcgattt tatcccgtca atacaacaat tagaatcatt
     9781 agcagaagtt ctaaattttg aaccaacaga tctatttata aatgaatcaa ataaatcaaa
     9841 cagaacaaaa catcagtcga agaatattgc tgtagccggt actggttacg taggtctttc
     9901 cattgctact cttcttgccc agcacaatca ggtaacagca gtagacattc ttcctgaaaa
     9961 agtaaaacaa attaacaata agaaatctcc aatacaagac gattacattg aaaaatatct
    10021 agctgaaaaa aatcttaatt taattgcaac gactgatggt gcagccgcct atagagaagc
    10081 cgattttgtt gtcattgctg ctccaacaaa ttatgatagt aaacaaaatt attttgatac
    10141 ttctgctgta gagtcagtaa tcaaattggt gttagaagtc aatccaaagg caataatggt
    10201 catcaagtcg acggtacccg taggctatac cgaaagtatt cgtaaaaaat acaatactaa
    10261 aaatattcta ttcagcccag aatttctcag agaatctaag gcattatatg acaatctata
    10321 tccttcgcga attattgtcg gcacggacca aactgacaaa actttacgag aagcctctca
    10381 cacttttgca gatttactcc aagaaggagc aatcaaaaaa gatatcgaaa ctcttttcat
    10441 gggattcaca gaagctgaag cagttaaatt attcgctaat acttaccttg cacttcgagt
    10501 atcttacttc aatgagctgg atacttatgc agaaatgaaa ggactaaata cacaagaaat
    10561 cattcacggg gtttgcttag atccaagaat tggcacacat tataataatc catcttttgg
    10621 atatggaggc tattgtttac cgaaagatac aaaacaactt ctcactaact ataacgatgt
    10681 tcctcagaat atgataagtg caattgtcga tagtaatcgt acaagaaaag actttatagc
    10741 agatcgagtg ttagaacttg ctggcacgta tgaggctaac agttcgtgga atgcagaaaa
    10801 agaaaaagag gtagtcatag gtgtataccg tcttacaatg aagagtaatt cagacaactt
    10861 ccgtcagtca tctattcaag gagttatgaa gcgaattaaa gcaaaggggg caactattgt
    10921 aatttatgaa ccaacacttg aaaataacac tacatttttt ggttcaaaag taataaataa
    10981 tttagatgat tttaaaaata tcagtcacag tattattgct aatcgttacg atagtaatct
    11041 tgatgatgta aaagaaaaag tatataccag agatttattt caacgagatt aaaaaataac
    11101 acctcagatt tgtagtgtct gaggtgtttc tataaacttt tataagtaaa aaaatacaat
    11161 tatacttcat aaaaagactt ataccactgc gcaaatttac gaagcccgtc acgcaaactt
    11221 gtacttggtt taaattcaaa atctcgttct aacgcactag tatctgcata agtaactggc
    11281 acatctcctg gttgcattgg aactagttcg gtatgagatt caaagtcgta atcttctggt
    11341 agcacccctg ctgcaattag ctcttgttgt agaatatcta caaaatctag taggttttcc
    11401 ggcgtattgt taccaatatt ataaatatga tatggtggga ttggtagccc atcttcccca
    11461 tcaattttct ctggagcgca ctgcataacc ctctttactc cttcaacaat atcatctata
    11521 taggtaaagt cacgcttgca attcccataa ttgaatattt ggatattatc accagcacga
    11581 agtttatcag taaaaccaaa ataagccata tctggacgcc cagcaggacc atatactgta
    11641 aagaaacgta accctgtaga cggaatattg taaagtttag aatatgcatg tgccattgat
    11701 tcattacttt tcttagttgc tgcatacaac gatacttgat tgtctacttt atcctctgta
    11761 gaataaggaa ttttcttatt agtaccataa acggaagacg atgaggcata cactaaatgt
    11821 tccacaccag attctccatt atcatatgaa tgacgacaag cttcaagaat attatagaat
    11881 cctattatgt tagattcgat atacatatct ggattagtaa ttgaataacg gactcctgcc
    11941 tgagctgcta aattcaccac gatacttggt ttataattat caaagatgaa atcaattgtt
    12001 gctttatcag caatagaacc tttgataaaa ttccaagtag atcctggatg gttctttgcc
    12061 tccgtttcta tctctgataa tctatagttc ttaatagaga catcatagta atcattcata
    12121 ttgtcaatgc caatgatttt tattgatgac tgagtacgta ataactcaag aaccaaattt
    12181 gatccaataa aaccggctgc gccagttatt aatattgttc tatttgataa ggacgtgttt
    12241 aattccagca ttttttagca ctcactttct ttttttctta tgaatacata tttgttatat
    12301 attaaaaaat cttatttaga cttatctatt gtcactttta tcattctaat ctttgcacgt
    12361 agtagaataa ttatacagat aggaaattgc taagca
//
LOCUS       DADVXV010000084        12273 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.085, whole genome shotgun sequence.
ACCESSION   DADVXV010000084 DADVXV010000000
VERSION     DADVXV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.085"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            172..1581
                     /gene="istA"
                     /locus_tag="KB969_002290"
     CDS             172..1581
                     /gene="istA"
                     /locus_tag="KB969_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBB6870248.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            1578..2306
                     /gene="istB"
                     /locus_tag="KB969_002291"
     CDS             1578..2306
                     /gene="istB"
                     /locus_tag="KB969_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBB6870249.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(2434..3345)
                     /locus_tag="KB969_002292"
     CDS             complement(2434..3345)
                     /locus_tag="KB969_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6870250.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(3362..4369)
                     /locus_tag="KB969_002293"
     CDS             complement(3362..4369)
                     /locus_tag="KB969_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBB6870251.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(4366..6495)
                     /locus_tag="KB969_002294"
     CDS             complement(4366..6495)
                     /locus_tag="KB969_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6870252.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(6500..6643)
                     /locus_tag="KB969_002295"
                     /pseudo
     CDS             complement(6500..6643)
                     /locus_tag="KB969_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(6796..7983)
                     /locus_tag="KB969_002296"
     CDS             complement(6796..7983)
                     /locus_tag="KB969_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBB6870253.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            complement(8076..10421)
                     /locus_tag="KB969_002297"
     CDS             complement(8076..10421)
                     /locus_tag="KB969_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBB6870254.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLENGITSI"
     gene            complement(10408..10797)
                     /locus_tag="KB969_002298"
     CDS             complement(10408..10797)
                     /locus_tag="KB969_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBB6870255.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            complement(10847..11743)
                     /locus_tag="KB969_002299"
     CDS             complement(10847..11743)
                     /locus_tag="KB969_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6870256.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            complement(11746..>12273)
                     /locus_tag="KB969_002300"
     CDS             complement(11746..>12273)
                     /locus_tag="KB969_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoesterase"
                     /protein_id="HBB6870257.1"
                     /translation="NSDLISEYKNEIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIE
                     DLKKQVEKLSHKSYKDVYDEYSKETDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGI
                     KVTDEIDEHRGELIKNLVTNRAKIQTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRY
                     QRGIKNLVKSYLKMN"
BASE COUNT         3695 a         2596 c         2028 g         3954 t
ORIGIN      
        1 ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa tttaactaca
       61 cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact ggtttccttc
      121 catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac tttggatgat
      181 attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca gataagaaaa
      241 gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca actattcatt
      301 acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga aatcatcggt
      361 agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc caaagctatc
      421 catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg tgtatacatt
      481 tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga tcgtcttgat
      541 catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca tgaagatcac
      601 atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac gtccgcaagt
      661 gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact atttaatcaa
      721 tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt gaaaaaaaca
      781 aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac cattcattat
      841 ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca tgtcgaaaat
      901 aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga ctcttttgag
      961 tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac gcattattca
     1021 aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca ttctcttcca
     1081 caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta tcacgaaatg
     1141 aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca attgactgtt
     1201 gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt aatgaacgaa
     1261 tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat gaaacaatgg
     1321 agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc tgcacgcctt
     1381 caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa acaattacta
     1441 agtttattag cgacctacga tatccaacaa attaatgaac aattttacga attagtcgtt
     1501 caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc attaacaaaa
     1561 acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa aagcttcgat
     1621 taagccatat catcacgaac ataccaagag cttctttcga agctccagaa caatttatta
     1681 ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa cggatggaaa
     1741 aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac gaagatattt
     1801 ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta aaaaggcaag
     1861 aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg atcgcattag
     1921 ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac aatctcgtag
     1981 agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag cgattcgaaa
     2041 caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa gaaggagctg
     2101 aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt attacctcta
     2161 atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca gctgctctcg
     2221 ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt ttcagattga
     2281 aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa ctctgcactt
     2341 tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac gacgtaattc
     2401 caaatgttgg attgctttta gataatcttt tatttattca caattgctaa tagtccaatt
     2461 ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg acaactcatc
     2521 aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt aaataggatt
     2581 cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt tttcaacata
     2641 atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct ctaaaaactc
     2701 ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt gtcttacttt
     2761 atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa tatgattgcc
     2821 tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg tctttttccc
     2881 ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt gtttttcaac
     2941 atctagaatt tttactgata caacctcgga actagtggga atatccgctc gaaccatatc
     3001 ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca ttctcttttc
     3061 aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta cagtaaaatt
     3121 ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat gagttgtatg
     3181 ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag acaataaaag
     3241 ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt ctttcttctt
     3301 ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc attcctcttt
     3361 tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta tcggtaagat
     3421 tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca taaatgccca
     3481 catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa tcgcctggtt
     3541 tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc acccgaggga
     3601 gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca aacccagttc
     3661 cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc tcgtcaaaaa
     3721 ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc actaataagc
     3781 aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc gcgatgggat
     3841 tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg gctaaagcaa
     3901 aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca tagttataag
     3961 cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc aaagacgaaa
     4021 aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt gataaacctg
     4081 ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact tgaataatcg
     4141 ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt tccaccattg
     4201 aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt ccagaactac
     4261 cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg cccacaaaag
     4321 agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc ttttctcacc
     4381 tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg ttcgctttgg
     4441 aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg gctgagtgct
     4501 tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat tcgaatgtac
     4561 ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg gttttatctc
     4621 cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt cgttcaatac
     4681 tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc gcaactcccc
     4741 tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt ttttcgtctt
     4801 ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta cttgattttt
     4861 tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc caacttttct
     4921 accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt gttttttcag
     4981 atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg acactctatt
     5041 gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac caactgctgc
     5101 accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca attttcgatt
     5161 catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat cattactttg
     5221 aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa aggtcacaat
     5281 ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa acatcgtgga
     5341 gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa tcgtattgaa
     5401 caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg acaataagaa
     5461 actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca acataatccc
     5521 tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa agaccacggt
     5581 tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat cttcaatctc
     5641 tgctttgact gcttcttccc gatccttacc cttattttca tccggactca cggataaaat
     5701 cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt gtaatagtaa
     5761 ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca cactatcttt
     5821 tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag ccgcttcact
     5881 aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg caatgaaaga
     5941 acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt tggtagtttc
     6001 tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca tcaataatag
     6061 gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg ctaaagtttg
     6121 gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt aagcttcttg
     6181 aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa aattggtaat
     6241 ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc aaggtaacca
     6301 atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat atttggaata
     6361 aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta ccgtaccgac
     6421 taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca caatccgaaa
     6481 aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga gtgtcaaaag
     6541 catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc ccatacaagt
     6601 cttgcatcaa gcattgaccg ttttcagtca agtccacaat cttgtgtaaa agttcaacct
     6661 catcaaaagc acaatgtttt gcgttgtgaa cctaactgcc atgcctttct ttctgaggag
     6721 agaggtcagg agcagtagcg cagcgactct tgatgtctct cctcagaaag aagagactcg
     6781 cacaggttca tggtgctaaa tgttattcga attaaattct aaatattttc gtggagaagc
     6841 cagccactca gtgtcttttt ccatcaaaag tgttccaatt atccgagtga tggaattgat
     6901 atttggaaaa atccgaatca ctcgttctct ccggcgaatc tcttcgttca accgttccaa
     6961 cacattggtt gtacgaatcc ttcggcggat attttcagga aaagacaaaa tttgaatagc
     7021 atcttcaaag ccgttttcta aaatgtcgca agcagcactt aattttgaat cacaaccata
     7081 tttttccaag aagtgctctt ttctttcacg tgtcaattca agttcagagg ctttaaagat
     7141 actcttcaac tcgtctttta catcagaaga aactttcttt ggcagcttat caaaaatatt
     7201 tctcaaaaag tgggcttggc atctttgcca gctcgcacct aaaaagttct tgcgaacagc
     7261 cttaactaac cctttgtgtg catcagaaat gaccagtttt acaccgaaca aacctcgttg
     7321 aacgaacgat tgaaaaacgg tatcccaatt atcttccgat tcgccgtctt gaacatcaaa
     7381 accaagaatc gtacgtcgtc catcagaatc aatgccgata ccaatatata caccttttga
     7441 gacaatacga tgattttccc ttactttcat atacagggca tcacacatga aaaatggata
     7501 ttccgagcct tctaggctcc ggtttctcca ctcaaaaaca aatggatcca actgtttcat
     7561 cagatttgaa acgaatgatt tagaaacagt cgcaccatcc gttagcagtt caactgtttt
     7621 agttactttg cgagtggaga caccagaaat gaccatttca atcatggcag cgatcaaagc
     7681 tttttcgctt cgctgatatc tttcaaagat agtaggacta aacttaccgt ctctggttcg
     7741 tggaacatga agttctaacg taccaattcg agttgtaaac gaacgatcgt agtaaccatt
     7801 tctttgtgat tgccgttctt ctgaacgttc ataggcattt gcctgaatat attgatttcg
     7861 ttgttcttcc atcagctgat taaacatgat agtcataagt gtttttgcgg tatcattcgc
     7921 accgctttcg tttataattg cttgaatttc ttcgctttca aaagtaaaat gtacttgagt
     7981 cattgatatc agtcctattc gagtatgttt tctgcaaaaa acattgtact cctaactgag
     8041 atcaatggct tttttgatgc ttcactttta cacaattata tggacgtaat cccgttttcc
     8101 aaatctcgca ggcgtttttg attgctttga tcctcctgat ccaaaccaaa gaattccaag
     8161 gttttcttga tttcatgaat atcggtactg cgaaaagcaa acttcaaccc gatattattt
     8221 tttaaacgtt catctaataa atcgtcgcta ttttgagtga cgaaatagac cccagcattc
     8281 atggcccgac cagcacgaac aagcttattc gataacgttt ttccttgagc cacttgaaga
     8341 aaactccaag cctcatccaa atcgacaatt ttgaagattt ctcggttact atggataaag
     8401 tccaaggcaa aagtggaaat gacgattagc atcgaaacac taagcaattc catggtggta
     8461 tattcttcaa aagtcgtttc tgcatccggt aaaaccaaat ccgccacttg aatgatattt
     8521 agctgtttat ctaaactaat cgattgggta atcgagccgt ctgagaaaag caaatgagca
     8581 aaatcataat cggtaaagga ctcgatatga tcggcgatat tttccgcgat tggtgacccg
     8641 tcttttcgca attcgttaat aacttgtaat aacccccgtt gatcactttg agtcaccgtt
     8701 cgaatggctt tacgtaacac aggaaacttc tccccgtctc gacttgaaat tcctgttaaa
     8761 aaagtcagaa tatcaattgc taaactttcc gagtctttct ttttcttcat aatcacataa
     8821 ggatcaagca gaccttgatt ttctgactta ctcgtcaagt tgaggatact gatttcatcc
     8881 gcaatttctg gcaaggtttc tttccaccct cctcgctccc cttttggatc gacaatcaca
     8941 gcttgaccac cgaacaaaac agcatagtag actaagagat tgttactaaa ggatttacct
     9001 ccaccaagag aacccaggaa agcggcggcc agcgcattgg ttactgaacc cttgactcct
     9061 tgtgaagcca atgccggttt caggtaaaca ttacgacctg tatccacatt gtagccaaag
     9121 taaatccctt ctaattctcc tagcatctga gtagccccaa aaccaagccc cgccaaaaaa
     9181 tcagacgtaa catactgaat atagtcgttc atatatcgtt tacttgaggg taagaattct
     9241 tcatgtagcc ccatcatatc gccaaagggc cggactagtt ttacattggt atcatcataa
     9301 aaatcgagca cttcatcaca gcgtcgcttt agttcatcca ctgattcggc actcactcga
     9361 accacataac tcagtttgta catagattct tttgactgat ccaaggtggt ttccaattca
     9421 tccacggaat ccaaagcatc taagacattg gaattcgttt cattgtcaga ttggtaagca
     9481 tgattgtcta aatctttcag ttcttttttc ttattacgaa cggtagctaa agccttttta
     9541 ttcgtcacaa tctctacatt catacttgtg tcgattggga atgtaaattg ttgttgctgg
     9601 taatagaaaa gttctgagga aggaaattcc atctccccca caattgtatt aattgttaaa
     9661 tacgctacgt acgactcatg attctcatgt tccatccgta agcaccttgg tttttcttca
     9721 attaaacaac gatttggacg taataagtca taacgtttca ccagtgtttc tgattttagc
     9781 tttttctttg gtagctgaaa ttcgtattct tcaaacggta tccctttttc gccataaata
     9841 tgttcaatca aatacgtcag gtcactcggt gtgactcgcc tgactttaaa tcttcgagcc
     9901 aatttgcttt ccattaattt ttcaagctta gaatagcagc gaatttcttc attggataag
     9961 gaaacaaaat cgcccatcaa atgatgattc actccataga caaattcttg aagcccagaa
    10021 aagaaagatt tcttgagact ctttagattg acttcttcat ctgtcgcaat tagtttaaag
    10081 ccaataaaaa agcgataatc aatctgacta tcgccaatca tggatactaa tgcatctgtc
    10141 tgtatatcaa ttcgttgttt cgctacttct ttgagtctac cggtaatttc tttttttgat
    10201 cgttcttgtg tggcgcgaat actactttct gtggcaattt gtaacgcatg gatcttgcct
    10261 tcacgatttt gcgcaattag ttggcgaaag ttatcatgca cttgaaattt ctgttcgggt
    10321 gacaaaaagg agtaattgta aggcactaat tcatagtagg caaaacactc gccttcttgg
    10381 ttaaagacga gattattttc aatatactta atcggataca tagttcacac tccttacaag
    10441 agtactgggt tcatcccatc gtttcttctg ttctttgact ttctttcctg caaaagtcac
    10501 cttaaatcgc aagtgatagc tgataaagga tcgtaaaaat cccagtggtt tcttgccatc
    10561 aaacgtcttt tgcgacataa accaagtgac agccaccggt atgcctaagt attttaaaaa
    10621 gacctcctct atcatagata gtggaggcac atgggcaaat acgatgacaa acagtaaaga
    10681 taaaacgaac caagccattt ggttaaaagt cacaggaaaa ggcaactgaa aatcattgat
    10741 tgcgtaaatg actttttcaa ctgcccagat actggtatag ctttttattt ttttcatttt
    10801 tcctcctaaa aagggcggac ataataatat gtctcaccct ctagtgttat tctacaattt
    10861 gtttaaaacc atagcgtttc gctctatttg taaaagcatc ctcgccacct tccatcacag
    10921 tacatattct tggcttgata ttgggttcat ctaccgaccc gcactgatca gccgatattt
    10981 cttttgaatc tcccatgcta atcaaccatt ctgaatcacc attaactggg atatttgcat
    11041 tatgagttac aattaaaatt tgtctgtttt ccttttttgt aatgatactt cttacgatta
    11101 agttattaat taattgacta tccaaatcat cttcaggctg atccaatatg agtggtgaat
    11161 ttccatacgc caaaatcata gaaagaattg cagatgtctt ttgaccagca ctagcattcg
    11221 ataaactaac tttttttcca tttagttcaa gtcggataac tactaaatca tttggcttaa
    11281 gggtttgtaa ttcaagaact tgtgcatcat tcaattttct tatagaattg attaattttt
    11341 tatctgaaaa aatactactt tccccactaa ctcttatatc aagtatgtca ttatatatat
    11401 cttgattagt aatggaattt tttgtcagct tatcaataag agatccaaac tcactgtcaa
    11461 aagtgtcctc cttattaata caagctctga gctctttaac ataattattg aaatccctat
    11521 ttggttgaat agtagcctct attcctgtaa tatcagaaaa aatttcgcgc gaggaactac
    11581 ttctctcaga atagagattt tgatatgatt tattcattct tgacattgct gagtcaacct
    11641 caacttggta atctttaagc tttatttctt gttgaataat ttcttccaat cgctcttcag
    11701 tttttgataa agattgatat aaagaatcaa ggttttgtaa catttttaat tcatcttgag
    11761 ataactcttc actaagtttt tgatacctct ttgatacctc tttgaaacct cattatagtt
    11821 aactttccaa tctgatttat tcagctctgc tctataacta tcaatttcat ctgacatttc
    11881 attaattatt gtttgaatct tagcccgatt ggtcactaaa ttcttaatca attctccgcg
    11941 gtgttcatca atttcgtctg taacttttat accattgcca aagtcaattt tgtcaacact
    12001 atcagttaga tttttgggaa tttccttaag tgcctccaca tcacgtttca gttccctata
    12061 aatatctgtc tcttttgaat actcatcata aacatcttta taactcttat gagatagctt
    12121 ttctacttgt ttttttaaat cttcaatttc aagctctacc ttcgccttat cttgtatttc
    12181 ttttttcaca gaaacaatat cccaatttaa ttttcttatt tcgtttacac atgtttcaat
    12241 ctcattttta tactctgaaa tcaaatcaga gtt
//
LOCUS       DADVXV010000085        11804 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.086, whole genome shotgun sequence.
ACCESSION   DADVXV010000085 DADVXV010000000
VERSION     DADVXV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.086"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..195)
                     /locus_tag="KB969_002301"
     CDS             complement(<1..195)
                     /locus_tag="KB969_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870258.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNY"
     gene            complement(211..825)
                     /locus_tag="KB969_002302"
     CDS             complement(211..825)
                     /locus_tag="KB969_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBB6870259.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(972..1655)
                     /locus_tag="KB969_002303"
     CDS             complement(972..1655)
                     /locus_tag="KB969_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6870260.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(1764..2222)
                     /locus_tag="KB969_002304"
     CDS             complement(1764..2222)
                     /locus_tag="KB969_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBB6870261.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(2306..4069)
                     /locus_tag="KB969_002305"
     CDS             complement(2306..4069)
                     /locus_tag="KB969_002305"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBB6870262.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(4290..5750)
                     /locus_tag="KB969_002306"
     CDS             complement(4290..5750)
                     /locus_tag="KB969_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870263.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(5958..6884)
                     /gene="glsA"
                     /locus_tag="KB969_002307"
     CDS             complement(5958..6884)
                     /gene="glsA"
                     /locus_tag="KB969_002307"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBB6870264.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(6907..8334)
                     /locus_tag="KB969_002308"
     CDS             complement(6907..8334)
                     /locus_tag="KB969_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6870265.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(8365..9579)
                     /locus_tag="KB969_002309"
     CDS             complement(8365..9579)
                     /locus_tag="KB969_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBB6870266.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(9920..10162)
                     /locus_tag="KB969_002310"
     CDS             complement(9920..10162)
                     /locus_tag="KB969_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6870267.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(10194..10751)
                     /locus_tag="KB969_002311"
     CDS             complement(10194..10751)
                     /locus_tag="KB969_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6870268.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(10764..10952)
                     /locus_tag="KB969_002312"
     CDS             complement(10764..10952)
                     /locus_tag="KB969_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6870269.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(10965..11531)
                     /gene="amaP"
                     /locus_tag="KB969_002313"
     CDS             complement(10965..11531)
                     /gene="amaP"
                     /locus_tag="KB969_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6870270.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         3461 a         2447 c         1933 g         3963 t
ORIGIN      
        1 gtaattaaac aatccgctaa tcgtttgatc tggcatttct atttccttac catctaaagt
       61 aacagtagta acgacaaaat ggtcttgcaa tggcggaact tctaagtact gcccttgcag
      121 aaaatcattc actgtttcat attctttttt catttctttt gaatctgtcg atggtttata
      181 gcttattttt aacataacta gtgctccttt ttattcggga cgtgcaatcg tgaaaatttc
      241 tcctattgct gcataatcat ttcctgccaa acggcttaca gcattcaatt ttcttggatc
      301 gatccttcct gtcttatcat catagactgt ttcatttaaa tgatatttct gtacttctag
      361 caaaaataaa tcagctgtta ctttattttt attccgtatc tcgacatgtt catataagga
      421 tgtttcaaaa cgaacttttg cttctgtcaa tgctggtact gaaatgatta ctgaatcagt
      481 taaagtcaag tcagtcaggt acagttcgct ttcctcatta ggcagattgg ctgctgtttt
      541 atttacttct tctacgttgt cctcatcaag gatatggata acagcttctc ttgtctcaag
      601 aatattcttt gctgtgtctt ttactgcatc ttgttttctc tggatcgcca aggataagat
      661 gggtcgattc gaactgacga tattgaagta actgaagggt gcgatattca ctatatcttt
      721 tgctgattta gtcgttacta ctgctactgg tctagggatg actgaaccaa tcagcaactt
      781 gtaattttca cgttctgtca attctgaagg actccgttca aacatggttt cgccttcttt
      841 ctataaaatt cgttaaaaag cagatcttga agacaaaatg aaaagtaatg cttttttcat
      901 cttcttagaa tctgctttaa actatctatc aatttttctt ttttgtcaag aatctgtgcc
      961 gtgcgtgttt tttagttatt tgctttactt gcggcttcga catatctttt agtgatcaat
     1021 tgcggacggg tgataataga tccaactacg actgaaaaag cacctaattc atatgctttc
     1081 tctacttgtt caggagagtc agtatgtcct tccataatta ctgggatatc gacttgttct
     1141 atgatttgat tcaataaatc aaaatcaggt gtctgcgtct ttcgtgaata ttctgtatag
     1201 cctgctaaag tcgtagacaa aagatcaaaa ccatcttctt gcgcttgaag cgcttcctca
     1261 aaagtcgaaa tatctgccat agctaaccga ccgtgttcgt gaatcatttg gacaagttca
     1321 gcagttgttt tttctgtcgg acgtttacga gaagttgcat ccagtgcaat gatttctgct
     1381 tgcgtctcca aaagttcttc cacttctttt tctgtcgcag taataaacac ttctgaccca
     1441 tcgtaatctc ttttgataat ccctattacc ggtaaatcaa cgattcgctt gatttcattg
     1501 atatcttctg tcgtatttgc tcgaatacca actgctccgc cttcttttgc agccaaagcc
     1561 attctcccca taataaaaga actgtgtagc ggctcgtttt ccaaagcttg acaagaaacg
     1621 acgactccgc ctttgatttg ttccagtgta tccacaatat ctcctccagt aatgttatat
     1681 aaaaatacag cttcatataa aaatgtaacc cttttctatt caggagacaa taatgagcta
     1741 tttctttcag cagacctttc ttactaaaag aaaattactt caaattcttc gtatacgacc
     1801 agcttctctt ctgtaaattc tatgttcaac gcttctttat aagcatgttt aaaaaactca
     1861 gcatggactt tccgccaata agctaatgtc cgatcccctt ctccttcttt ccaagcatgc
     1921 tctttcgtga cttcactaaa aggcaagatg gtcacattta tatttttgat gatacaaact
     1981 ggttcatttt ttccattcag gaccacgtct aattgaccaa cttttggtaa aggctcattc
     2041 tcttgtttat acagatcgta accacttgat gtaccagtct ttatcttttt tacaactagt
     2101 tcgctcaact cgtctgccat tttttctgta tccccaaatg aaaagaaacc taatttttct
     2161 gattgataac taggatattt ttcttggaac tttttgacat attcttctac ttgctgatac
     2221 ataacatcca cccctttgct ttttataatg aaaaaaccat ccagatacta gtataaacaa
     2281 ttatctggat ggtgagcata atgaattatt gaatattcaa gacacgcaga ctatcttcaa
     2341 cgatttgttt tggtgttaaa tgataacgtt cataaagctg ccctacagga acgctatccg
     2401 tgaattcttt ctctgcacca aaatttaata cgttcattga agaatcacca taataacgac
     2461 tgatattttc gccaaatcct cctgacaaac taccatcttc taatgtgatg actaattcgt
     2521 gtgtttcttt taatttatct aatgtttcta cgtcattttc tgtgatcgtt cctggattga
     2581 tcaacgttgc ttcgattcct ttttttctaa aagcttttac tgtttctttt cctaattcaa
     2641 gaaaaccgcc taaagctaaa attgctactt ttcctccatt atttactgtt tgataggctg
     2701 gaatactata atcatttgcg atagctgtac catgttctac accatgtgta ggaattcgga
     2761 ttgctacagg ctgcgctgtt tgttcgaacg cccaatctag catagagatc atatcctctt
     2821 ttgttgctgg agcaagatat ttgatgttcg ggatacttga taagtaagga atgtcaaatg
     2881 ttccttggtg tgttcggtca ctagctgaga tcgttccgcc accgactaaa ataatcactg
     2941 gattctcgtt gatcgctaaa tcatgtgata attgatcata tgcccgttgc aagaaagtac
     3001 ttgattggaa gacgactgga cgtactccct gagaagccaa agcagaagcg aaagtgatag
     3061 agtgctgttc agcgatcccc acgtcaaaat aatgatctgg atgtttttct tggaatgttt
     3121 tcagtccaaa ggcgcctggt atcgctgcat tgactgcggc aataggagct gtacttgttt
     3181 gcattttctt atccaaataa tccatgatga tcatattaaa tgtttctcca gaagttactt
     3241 gctttgcctc cccggtggac agatcaaatg gtacatgcca atgatatttc attttattat
     3301 cgattgccgg ctgataaccg cgaccttttt ccgtatggac gtgaagtaca atcggatgat
     3361 caatatcttt tacttcttca aataaacgga tcaccgtttc cagatcgttt ccattatcca
     3421 cgtaacgata atcaaatccc attgctttaa ataggttatt gctgctttta ccgttggttt
     3481 gacgaagctc agctaagttt ttatataaac tgccatgatt ctcatcaata gacatctcat
     3541 tatcgtttac taatacgatt agattggatt gtaaaacacc accattgttc aatccttcaa
     3601 aagctaagcc accacttagg gagccgtcac cgataaatgc taccacattt cctgattctt
     3661 tcttcagatc tctcgcttta gctaaacctg ttgctaagct gatagatgta gatgtgtgcc
     3721 ccactgtaaa atagtcatgt ttactttcat gttggttgga atatccgctc acttcacggt
     3781 aatgtccttt ttcaaaacca ttttttcgac cagttaaaag cttatgacca taagactgat
     3841 gggaaacatc ccaaacgatt ttatcctttg gtgaatcaaa tacataatga aacgcaatcg
     3901 ttaattctac tacacctaga ttcggaccaa cgtgcccacc tacatcgctg tccttttgca
     3961 agattttttg gcgcatctct tctgccaact gtttcatttc ctcaacagat aattttttga
     4021 catctgcggg gctattgatt gcatccaata catgtaatac tgtactcata atacattctc
     4081 tcctccgtac tatcttcttt taatgaaaat agatttgtta cactttatct attctactac
     4141 ttagagttga ctctaagtca atagcatttt aaaaaaattt cagagaaagc ttgttatata
     4201 agtagatctt cgcacgaatc aggactcaaa taaaaacctt ctacagacaa ttaaaaagct
     4261 ttgtagaagg tctcctaatt aaggtctcat caagaaatat gtttttttaa taggtgaagt
     4321 tcctgagcaa tatgatacaa atggatgttt gcacctttta atgagattgg atagatcttt
     4381 gtcttttcag tttctaatcc attttgatag ctagcagcat cgcacaaaac cactcttttt
     4441 ttcgcacata gacattcatc aggcaattct tctaatgaac gaaataaaat aggatttatt
     4501 tcagcgatgc cttcttccgc atacaaatga aattgggttc gataaaaaaa ttgtttgact
     4561 gaactttctg aaacaacaaa aatttctatt tcctgtctcc ccgcttgttc actgttgatc
     4621 aaagaaagac ttttgacgaa ttttcgaatg aaattttcat tccatcttag ttggatttga
     4681 tttttctttt tccactcttc caatatttct acaatttttc cgtacagaag ttgttctttt
     4741 tctgatagaa gatagatcct ttccggtaaa aatacttgtc catctgccca caacgtacgg
     4801 acaaattgta aaaaggattg cttgaaaata aaattttctg catcgtcgat ttcagcgata
     4861 ctaataatct gtaaaatcaa ttcattcagt gataggtcat tgagaacaaa atttttataa
     4921 acaacttcga aatcttttct taacagctcc atgttctcat tggtataatt tctactgttg
     4981 aacaaagaaa aaatataata gacatcttct tcttgtaagt ctagaattcc tttttgctct
     5041 tccaatcctt gacagactaa ttgaaataac ggcttcgttt ctgcgctttt cttatcttct
     5101 tctttcagtc caaggggaaa tgcctttctt ccgattgcga tctctattcc tcgtatgata
     5161 aaggactttt catcttccga atatcttctt ttaaaaaaat gagtctctac ataatcaatc
     5221 aactcgttac aagcttcttc tacatacgga tttttatttt catagccttc ccaattgaca
     5281 taacgtacta aagctagcaa gatgttccgc gagtcaaatt ctgggataat gatttcttta
     5341 tttttcaaat aatcattttc tttaaaaaaa tccaatacga tttttttgat tgtatatact
     5401 ttgctcaaag aaataaattc aagatcagcc agttctgtac tcgtgaatat accattaaaa
     5461 taataactta aaaactttaa aaaataagat tgaccgtaca gaaactgtgt gagctcagaa
     5521 agagcaatac catgtttgaa tacgagttta tacttatgct tctctcttac ttgttctttt
     5581 atacaatatt ctagacactc ggctagactt tctagatcgt gaaggatcgt tggtgtagtc
     5641 acccttagag aaatagctgt ttgttcgatg tctatttctt ggaattcaaa taattgttca
     5701 cacagataca cttttctaaa tatatttcgc tcgatgtaat tttccagcat tcctgataca
     5761 cgcctccagt ttttcttatg attttattta atcatatctg taaatcgtat ttttgtttcc
     5821 tttttattta gaaaagccct ttcaaaaacc aataaaaaaa gaaactggga caaaagtcaa
     5881 acaagctcac aatttcagcc tcattgtagg tagctttgag ccgtttggac ttttacccca
     5941 gcctctttca agaatggtta ttcaaagatg tcagcgtcta gttctttgac tacatctttc
     6001 aacaattgga taccagctgc gctgttacca aatggatcta gtgccgggct gaagacacct
     6061 atgccgtaac gatttggcac agctgccatc aacccgccgc ctacaccgct ttttgcaggt
     6121 acaccaacat ggacggaaaa ctctcctgat tcatcataca aaccagcagt tgtcataatt
     6181 gatttgacga ttgtagcact ttcttcagta atgatttgtt tgccattcca aggagcaatt
     6241 cctttatttg ccagcacagc agctaatttt gctatgcctg tagcggtgac attgagggag
     6301 cattgtctga aataagcatc gagtatctcc ggtacgtctc cttcgatcat ttgattacct
     6361 ttcatatagt aagcaagaga gcgattgata tcacctgttc ttgattcaga atgatagatt
     6421 tcttcattca atgtgatatt aggatcatca cagatctctt tcataaatga caagattcgc
     6481 tcaaattttt catctgcatc tttaccggca atcaacgagg ttgttgcaat cgctcctgca
     6541 ttaacaaaag gattcattgg atgtttgcga tgattgattt ccatattcat gatagaattg
     6601 aaggcaaaac cggttggttc cgtgttgatt gtttgaaaga ctttttctat tccgttgtct
     6661 ttgattgcta ataacaatac gggaactttt gacatgcttt cgatggcaaa gcgcacatcg
     6721 gcgtctcctc cctcaatcag ttgttttgta tccaaatcat aaatcgccat acctaattgt
     6781 ttgggatcca cttcagctaa tgctggaatg taatccgcca cttgtcctgt ttgataatag
     6841 tggaaatttt ttccaatcaa ttgttctaat tcttttactt ccatttgaat aaccagcttt
     6901 cattttttat ttttctgcat gctggaattt atgacggcat gcgtagatcg taaatggaat
     6961 aactaagacg ataagataag aaacaatcag aatcgtttca taaatcccat gctgtccagc
     7021 tgcgatacta gcaggtggaa caaatgagat acaaaaagca aaaagtgaag tcaaaagacc
     7081 taaacaagca acgattactt ttacaacttt tccgcctgga acctgatagg ctctttcaag
     7141 actgtcatct ttaaaaacca gcttcaaata gcccgcgaaa aacataaagt acaacatcag
     7201 gtagattaca acagtcaatg acatcgctgc aagaaatgaa agattattcc ccccgccgct
     7261 taatgtaaag acggctgccc agattgttgc aacgatccca tttgcgatca tcaaatgagc
     7321 aggaacaccg tgtgtgtttt cttttgcaaa atattcagga agtaatcctt cttctgctgc
     7381 tacgtgaagt gcttttgaag gagaggttac ccaagaagca atttctccga tgacacctaa
     7441 acaaacaaga atcgcaagaa ttttcgcaat ccatgcaaga tttggatcaa tgtgtcttaa
     7501 taggaattct aacgattgaa tcacccctgt attaagagac aaaccatgtt gaggtactgt
     7561 agtagcgacg gtcaatccgc caaaagtatc taaaatgatt gccagaataa ccaatacaaa
     7621 cattgctaat ggataatcct ttttagggtt ttccatttca tttgcatgac tggcagatgt
     7681 ttctacgccc atatatgcta aaataaagga aacaaaaaca accagcgtag gcaatttcga
     7741 aaaatcagga atcaatgttt tcatagacag tatcgtttgt agtggagcgc ctgaagcgac
     7801 ataatggatc cctaagccaa acaagactaa tgctggcaac aagataccag ctacaaaacc
     7861 gatccgagca atcaatgaag tgtatttggt tccttttaac tgtgagagta aaatagccca
     7921 gaaaataatc aataggattg ccaatttcag atatttattg ttttgtatag caccaatacc
     7981 cgttgcatag gataatgcac cagttaagaa atacagcatg gtcaagtagc caactgttat
     8041 ctcaaaccat tggaaaaaga ttgcggcaaa accgaatcgt tttcccaatg tgcgactgac
     8101 ccaagtatag acaccgcctt tttcccatcc tttcaccgtt gccatctctg ctgcgcacaa
     8161 tgccacaggg ataaaccata gcaaaccgcc taataacaag aaaaatacta agctgaagcc
     8221 tgaggtcgcg aatgtgggat attcatataa tgaaacgacc attgagatgg tcatagccaa
     8281 aaagccaaag aacgttaatt tttttgcagg aattttcgtt ttgctttgtt gcatgaatct
     8341 tcctcttttc tatttgaatt tgtttcaatt gagtttgttg ccaaagaaga aaaagtccaa
     8401 tccttcttct tgttcttctt ttgtagtagt gatcgttgta aagtgcatcg ccgattttaa
     8461 aatcactgtt gtcagcacat aggcatacac ggcagtaatg atgacaccaa tcacttgaat
     8521 ccctaagaag taccagctgc ttggattcgt tagtaaatgg ctgttagatg caaagatccc
     8581 tatcagaatc gtacctgtga atccgcccat gccatgaaca ccccacacat caagtgcatc
     8641 atcccattgt ttctttttac gaaaatcaac agcagcatga cagacgatac ccgcaatgat
     8701 cccaatcagc atggcacttt ttgcttctac ataaccggca caaggcgtaa tggctgccaa
     8761 tccagcaacg gatcctgtta gtacgtcgac aaaatcaaag ccatttcctt ttacttttgc
     8821 aatgatcagc caagtaatca tcgcaaatgc aagagcgatg aatgttgaac caaatgcatt
     8881 gactgcttgt tcatctgctc gaagtgcacc accggaatta aaaccgaacc agccaaacca
     8941 aagcagtcct gtaccgatag cagctgccat aagactgcta tgctgacttc tttctcctaa
     9001 aggaatcttt ctttgaccaa gtgtgaggat acatgctaaa gagccgaatc cagctgtcgt
     9061 gtggatgact gctccaccag cgaaatctct aaatcccatc tgatccaaaa atccgccacc
     9121 ccatatccag tggcaaacag ggaaataaat cagcagattc caaaaaataa caagtataat
     9181 atagcctttt aaattcaatc tccctgcaaa agctcctgtc atcaaaggaa cggtaatcac
     9241 gataaacatc agttggtaaa gaaagaacat taaaaatgga atcgttgcac catgaaacat
     9301 gttggggaag cttgtaacat gtctcatcaa aaagaaatct gccgggtttc caataacacc
     9361 gccgatatcc cgtccaaagg ccaatccgaa tccaccaaat acccacataa tcgttgttat
     9421 cccaacggag agaaaagatt gagacatgat cgttagtata ttattcttcc gtgctaatcc
     9481 gccgtaaaaa aaagctagac caggagtcat caggcaaacc attgctgtac ataaaatcat
     9541 gaatgctgta tctcctgtat tgataggtaa tgtattcatt tttttcgcct cctttctacg
     9601 attacgagta taaaagaagg tgtagttgtt tttttcttct gtttttttga attaatactt
     9661 gcatttataa aagacagaca attaataaaa gcttgatgtg ttgtgctctt tttcgttttt
     9721 cacacaaata aagacaaaaa ataaacggtc ttctttttat agaaaaccgt ttattttcgt
     9781 ctttttttat ttttaaagat attttttcat aaggaataaa gaatacttca tataaaatat
     9841 ataaaaaaga accgcagcga gtgtcgctac ggttctcaaa tttgttcttc atttcaacat
     9901 aagtttttct tcaatttgct tataatttac gtgcaaagaa tgaaacgact aatactaaaa
     9961 tgattgcacc gatcaatgat ggaatgatag ccattcctgc aattgttggt ccccaagttc
    10021 ctagtaaagc ttgtccaatt gctgaaccta ctaaaccagc aatgatgttt gcgatgatcc
    10081 ccattgatga tcctttattc gtgattgctc ctgcaattgc tccaatgata ccgccgacga
    10141 ttaatgccca aataaatccc attttaaatt cctcctaact gacttcttac ttcttattgt
    10201 acacgtggtt cgttattttc tttgactttt tgtgcacctt tgcctacagc agattttgct
    10261 ttatctgttt ggcgtgaagc aaattgtcct gtggattttg ctgcttctgt tactttgtct
    10321 tgtactgttt cttgatcttt ttggtattct tcttgtgttt tgatgtctgc aacattcaca
    10381 ttcacttcga taacatctaa atgtgtcata ttgtttactt cagtactgat caattctttg
    10441 atttggttgt aaatatcttc gatgtcttta ccgtattcta cgatcacatc tagatccaca
    10501 gctacttgtt tcttacctac ttctgtattg atacctgctg ttacgttatc tgtgttgact
    10561 aatttttcag ccatatttga gaaaaatccg ccatctaatg tcaatagacc atctacatct
    10621 ttcaatgcat aaccgatgat tttttggatg actttgtctt cataagtcaa ttcaccattc
    10681 atcatgcggt tttctccttt ttcatttgcc aaaactgatc catttgttgt attcatgttt
    10741 ttgttttcca tctttgtttc ctcctatgat ttaaaaaatt gatcaactat tcctgactgt
    10801 ttcaaataaa aaccgattcc tgcgccaatt gctgtcatga ttatgatcaa caatgtcttg
    10861 aaaaatccaa tcgttaacca taaaacagct agcagtagtc caagaccccc aaagataata
    10921 gggagcttgt atgctgaaaa tagttctttc attatttggc cctcctattc cactcgagag
    10981 tgcttgtagt ctcttgtatc ttcttgttct tcataaccgc tgtatgtgac tgccactttg
    11041 accgtttctt ttgttccgag tactttagtt acttcttctt cgatatcttg catcaataca
    11101 cctgttttcc ctactaatga agaagttcgt ttcaagtctc cgttgacatg gatatggatt
    11161 cgatttttcg ttgaacgtat ccgtacttta ggtgaatgaa tgaactcttc ttcgtgtaaa
    11221 tgggaacgta ccaacccttc gatcgctttt ttgtcgattg ttagtttgcc atcttcccgt
    11281 ttcataacga aagttcctct tgactttgga tagaaaagaa cgactagcaa gatgataata
    11341 gcaagaacgg caaatactac agctgcccag aaaatatatt gttgcatgta gtaattcgtt
    11401 aaagtaaaga agcgaaatcg ttccaattgt tcaggcataa tatacggcgc attgatcaac
    11461 gcaatcgcta gaaatactga aagtagcagt aaactcatga taacaccgat tatttttaac
    11521 cccttattca ttttccacct cctataaact tatttttacc ctgtaaataa ctctaccgac
    11581 aatcacagta tagatagcga acagttagca tagcatcagt aaataaagcg ctaccaaaca
    11641 ttgctggatc ataacggcgt tttattgcca gtctgatact gaaataacaa ttgcttactt
    11701 attctctatt tacttttgat tgctggctat acttaaagga tattattcaa gattaaaaat
    11761 tgcaaagatt atgctcagtt attattacaa gattctattt attt
//
LOCUS       DADVXV010000086        11781 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.087, whole genome shotgun sequence.
ACCESSION   DADVXV010000086 DADVXV010000000
VERSION     DADVXV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.087"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            508..1071
                     /locus_tag="KB969_002314"
     CDS             508..1071
                     /locus_tag="KB969_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870271.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1132..1497)
                     /locus_tag="KB969_002315"
     CDS             complement(1132..1497)
                     /locus_tag="KB969_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870272.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1573..1818)
                     /locus_tag="KB969_002316"
     CDS             complement(1573..1818)
                     /locus_tag="KB969_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870273.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1888..2142)
                     /locus_tag="KB969_002317"
     CDS             complement(1888..2142)
                     /locus_tag="KB969_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870274.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2306..2629)
                     /locus_tag="KB969_002318"
     CDS             complement(2306..2629)
                     /locus_tag="KB969_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870275.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2816..2889
                     /locus_tag="KB969_002319"
     tRNA            2816..2889
                     /locus_tag="KB969_002319"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2850..2852,aa:Ile,seq:cat)
     gene            complement(3274..3771)
                     /locus_tag="KB969_002320"
     CDS             complement(3274..3771)
                     /locus_tag="KB969_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6870276.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3811..4620)
                     /locus_tag="KB969_002321"
     CDS             complement(3811..4620)
                     /locus_tag="KB969_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6870277.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4954..5811
                     /locus_tag="KB969_002322"
     CDS             4954..5811
                     /locus_tag="KB969_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6870278.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5804..6706
                     /locus_tag="KB969_002323"
     CDS             5804..6706
                     /locus_tag="KB969_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBB6870279.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6739..7089
                     /locus_tag="KB969_002324"
     CDS             6739..7089
                     /locus_tag="KB969_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBB6870280.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7138..8061
                     /locus_tag="KB969_002325"
     CDS             7138..8061
                     /locus_tag="KB969_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBB6870281.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8139..9032
                     /locus_tag="KB969_002326"
     CDS             8139..9032
                     /locus_tag="KB969_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6870282.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9070..9633
                     /gene="amaP"
                     /locus_tag="KB969_002327"
     CDS             9070..9633
                     /gene="amaP"
                     /locus_tag="KB969_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBB6870283.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9647..9835
                     /locus_tag="KB969_002328"
     CDS             9647..9835
                     /locus_tag="KB969_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBB6870284.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9848..10750
                     /locus_tag="KB969_002329"
     CDS             9848..10750
                     /locus_tag="KB969_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBB6870285.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10782..11024
                     /locus_tag="KB969_002330"
     CDS             10782..11024
                     /locus_tag="KB969_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBB6870286.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11280..11651)
                     /locus_tag="KB969_002331"
     CDS             complement(11280..11651)
                     /locus_tag="KB969_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870287.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4175 a         1985 c         2232 g         3389 t
ORIGIN      
        1 tcattggtcg ttgaatgggc tgaatagtag tgtataaaac aattttgtgg agcgtgaagc
       61 ttttatggta gaggaaaata cgaataaagt gatgttgata aaaagattcc tatcttgaat
      121 atgaatcgag atgtcttgaa aatgaatgag tttgaccaat cattatccta tcgaaattta
      181 cagtttcgtt cgattggtct gtcaattaat gaaaaagtaa aaaagaatat gttctaggaa
      241 gagggcggca catctaaatt tttaagtaac ggacagttca aatatcaagc attgaaagag
      301 gctatcctac tgtttgaagg aatacgaata tataaaaacg acaaagagga aaaagtagtt
      361 cattaaatcc cttcaagtga tgaaagaatg agatctaata aaacctgatc tttcatctgt
      421 ttttttaata acgtaataat ttttttattt tttgtgcttt cgccgttatt gtagagtgat
      481 ttagcattct tatttttaaa aataactgtg ttatatatta aaaaaggcat aatagttata
      541 agctttttta aagaatattt agaaattatt aattttcgtc tgaaaacaaa aaaagaaagc
      601 gttattattt tagtctattt tcaggggggg aaccttatga taaaaaaact atttttacta
      661 tcaatattaa cgctagcaat ggcaggttgt tctgactctg gcttagcaac tgaactgatc
      721 acaaaatcaa ctgaagccac gacagaggag ttaaaatgtg gaaacgatca cagtgactac
      781 agaggcttaa atcgacgatg catgggaata ttaggcagaa gcaattgtaa gcatcgatgt
      841 agtaatcgaa gaaggtgtag aagaagcaac agaaaaatca aaagaaagat caaaagaagc
      901 aatctgtgct gtgcatcgta tacagacgtc gaagatgcgg tacttttaaa ccacgtcagg
      961 agatgttcat ttatgtctag ggaagttggc gatgaaccaa aactagagta cgcttttagt
     1021 tttgcacgtg aggatgaaga taaccctaaa acttacgaca ttttagcttg atctaagatg
     1081 gttaaagctt tttaatgaag taagaggaga tagaaggctt ttctagttat attaggtaag
     1141 ataaattcct ttttgctcca aatttgctaa acattctgct agataaactt catcgtgttc
     1201 cggataaatc ggcacgttgc gctctacagt aggtaaatca aaaaatgctt cgcatgattt
     1261 gccacgatac ataggatttt tccactctgg tgctgggctg taaccacgtt tttccatttc
     1321 atccatgaca agctgatgat attggaataa tctataagga gaatagtgaa aaacataatc
     1381 cacagtagca tgtttctttc cccagccatt tcctcttaat gcacagcatt cccgatgttg
     1441 tcctaaaagc tgttgacgag gaagctttga aatcaatttt tcatgccata atcgcataga
     1501 aatgtctcct ttatatatag attgttaacc ttagacgtta aatgaaaaaa ccagcaccaa
     1561 ggctggaaaa aatcacttca gtttgcttgc tgtttctgag cgaccaatta ggtaatcaac
     1621 ggaaatatcg taaaagtcag cgatatagat taattcaatg atgcttggaa tttcttctcc
     1681 ttcttcgtac ttacgatatt tgaataaagg aatacttaac gcgctagaaa cagctacttg
     1741 agataaagat cggccagttc ttaagaaatt cagacgacaa cgtaaagtat ccagtaaaat
     1801 agcttcttcg atactcattt aatcaccttt cattatagta gaatagttat aatgactata
     1861 gaaagctaca catgcaatca atagtactca atgtttttta tttaaacgta tcaaataaag
     1921 aatgacgatc aataaagaca aaaccagtcc tgataattct tctataaaaa cactatcggg
     1981 ttcaaagtag ttgtaattaa aaactttcca cataaagtag atagccggaa gagtcaaaat
     2041 agctaaataa aaccgttctt tgttccaatt cataagataa acaatacttg cgaccagtgc
     2101 gaccgcaggc acccaaaaca aaactctcac caacgtaatc atgtaacgga ctcctcaacg
     2161 attcatataa taaaagataa catgttattg catacatcac aaatgaaatg ctaggaaaat
     2221 aaaagaagaa tagatcaatg aaaaatgaaa aagcagaaca gttttctgct gataagcagg
     2281 aactgttccg ctgaatgtgt cttatctatc gagaaaaaat caatggattg atatctaagt
     2341 aattcaatac atataaaaag aggacgatcg cattcactaa aaaggaaaga atgatgatcc
     2401 catagcgaat ggaaacatat ttaacaaata cttttgtttg aatacgggca tatctttttc
     2461 ctttatagct gagcatcatg acaagaagca aaagggtaat cacaccttga aaaatcattc
     2521 caataaacag aattcctgag gtttgataat ttaattggag aaaataagct gctgccgcaa
     2581 ctaaatcgaa taaaatcgca ataaatggca aaataatcac tcctaacatt gagaataaat
     2641 aaaagaataa cattttttct aaaataagca aataaaaatt aaagtaacaa aatagttatg
     2701 acacaagtaa aagaaataag aataacaata ttattttact tatattttga aacttgtgag
     2761 agtttgtcat tcgtgctata gttgaaaagt aacaaaaata aattttattt atgatgtacc
     2821 tttagctcag ttggttagag cagacggctc ataaccgtcc ggtcgtaggt tcgagtccta
     2881 caaggtacat aagaggttgt gaaaaagctg ccctgcatca agtaataaga acagccaagt
     2941 aaaaacagct tcttatgttt ttacttggct gttcttatta ctgcagatgc aagcttttga
     3001 ataccgttta aggaagaggt tgtgaaatca gcgttttgac ctgagtatta gcttaacaaa
     3061 cggaaaaata gttcctcata ttttgccgtt tgttaagcta ataccgaggg tcagctgatt
     3121 gaacaccatt taagaaagag gtcgtgagcc tgccgtttca ctctgtgtca taaaaaagcc
     3181 aatctacttt gatagaaaaa gcacgtagga ctaaaacagt tctgcgtgct ttttttattg
     3241 tgtgttaaat atcgtaaatg aagatagata tttttatgat tcgacgatag agacgttgaa
     3301 atctttcaac agctctaaag cggattctcc gtgttttcta ctggagacta acattggatc
     3361 aacaaaaaag tctgcttcag gaaaagcact ctgcaggcct atcagattag agagtacaca
     3421 caagtttgtt tcaatcccga ctacttcgat ctctttttgt tcttctttgc tttcaaataa
     3481 agtttcctgg atttcagcta aagtttcagg tggaatcgta aagtaatact ttttaatcac
     3541 tcgttcattt tcttgtggag aaagaagagg gatcaattgc aaatcttctc gttcttcttc
     3601 tttgtccttc agttcaactg gtatatcccg tgtgaagaga atatattcat tattttggcg
     3661 tgctttagct aatctttgag caatacgttc tgccaattga tctgactctg gaatataaaa
     3721 ttcgctgttt ggatcaagaa tatgattttg catatcaata ataactaaca ttttctttcc
     3781 tcctacattc atatcgtcat tttattcttt ttaatagaag ttttttaaaa tataagcaac
     3841 accagcttct tcattcgtca gtgttacttg gtttgcaatt tcttttactt gtcgctgtgc
     3901 attccccatc gcaatactca acccgctgta attcaacata gcaatgtcgt tttcttgatc
     3961 gccaaaagcc atgatgtcac tcgattcgat tccaaggtaa tccgccagaa aaacaagtga
     4021 atgagcttta gtgatacctg taggcgtgat ttctaagaaa tgcggatcag agaatactga
     4081 ttggatacca tctgcttgca gatctctttg tagcttctgt agtttttctt cactcttatc
     4141 tgttaatgct aatttaagat agctaagaga aggatcttcc aacatattta aaatttgatc
     4201 aaaagaatgg ttctgtaaat tgaaatgttc ataataaggg tcatctttga ctagatttga
     4261 ttcatcgaat gtcagctgat catcttgggt ttctcggcta gcaatgatgg atattttcgc
     4321 ttcttgagca tagaagaagg cttttctcag tgtatcgcta tctatttttg aacgtctgag
     4381 aactttcgcc atttttccat ccttcatttc agcaatcagt gaaccattgg aagaaatcaa
     4441 atagccaccg attcctaatt cggaaaaaat atctttagca gaaatgctgt tccttccggt
     4501 agcgacggtt acgattccgc cattttcatc aaatttccga agtgcttgga tattttcttc
     4561 tggtatcttt ccatttcgat caagcaaggt accgtctaaa tcaatcgctg ctagtttcat
     4621 tttatcttcc tactttcttt ttacatatct attttcctgt taccttaaga ttaaatgaga
     4681 atttaaaaaa atgaaactaa cttgctttgt cattatgaat tttttcaaaa aacattctta
     4741 agaaaaaggt ggctatatat agtagttttt ggtcaatacc tttgaataaa aagccatgaa
     4801 aaacgaatag ttagcgctta ccgatgcgtt ttgtgataaa aaaattttaa aatattcaat
     4861 gaaaacaaag catatatttt gctttaaaac caaatgagga atattctaga tgtagaacag
     4921 gttagaaaaa gattagaaaa aggagtgatt ttgatggaga agagatacgg cgtagttcct
     4981 gtggtaactg cttcagacga aaattatgct ccttacttga gcgtgatgat cgcaactgca
     5041 ttagaaaatt gcaataaaac aagacgcata aaattttatg tgattgacga tggtctatca
     5101 gaatatagta aagaaggatt ggaagaaacg gtaaataaat attcaagtaa tgcaagtatc
     5161 caattcctga cagtggaaaa agatatctac gaagacttcc tagtcagtga ccatatcaca
     5221 actaccgctt acttaagaat ttctttacca aacttattag ctaaagagga ttataagaaa
     5281 gtcctttact tagattcaga tgtgttagta ctagacgata tcgtaaaact atatgatgag
     5341 ccgttaaatg gaaaaacaat cggcgctatt atcgatccag gccaagtgaa agctttggaa
     5401 agattaggaa tcgattccga tgacttgtac ttcaattcag gagtgatggt gattgacatt
     5461 gatcaatgga ataaaaaaga aattacagaa aaaactatcc attacctcag tgaaaatggc
     5521 gatcgaatca tctatcacga ccaagatgct ttgaatgctg tactttatga agattgggaa
     5581 caacttcatc caaaatggaa catgcagact tcgctgattt ttgaacgtca tccagcacca
     5641 aatgaaaaat atgaacgtca gtataaagaa ggaaatgaaa aaccttcgat cgttcacttt
     5701 acaggacatg ataaaccttg gaatacgttg aaagatcatc cgtataccaa tttatactta
     5761 aaaaaattag cacacagtac tctaacgaaa gtaggcgaga tcaatgaata aaaaagaaat
     5821 agcagtagtc gcaagttgta acacaaaatt cgtaccacat ttagctgcat tatttgtctc
     5881 agtattagat aattgcaacc cgtctaaatt tgttcggttc tatgtgattg acgatgatat
     5941 cgattttgaa agtaaacagc ttttacgctt ctcagtgaaa aacgcacgaa tgaactcaga
     6001 tgtggaattc ttgaaaatca ataaagaatt ctttacaaat gtggtaatca gcgatcgtat
     6061 tccagaaaca gcttattatc gtattgcgat tccggaattg ttccgcggca cagaagttga
     6121 acgtatctta tatatggatt gcgacatgat cgctttacaa gatatctcta aattatggcg
     6181 tcttgacttc ggtgattcaa tcgtagcagc tgttgaagac gctgggttcc atcaacgact
     6241 ggaaaaaatg aaaatttcag ctaaatcaat gcgttatttc aactcaggtt tgatgctgat
     6301 caatgtgaaa aaatggttag atgaaaatat tacgcaaaaa gtattagatt tcatcgaaca
     6361 taatccagaa aaattacgat tccatgacca agatgcatta aatgctatct tacatgaccg
     6421 ttggttacca cttcatccgc gttggaatgc acaaggctat atcatggcaa aagcaaaaaa
     6481 acatccaaca gcagcaggtg aacgtgaata cgaagaaact cgcaacaatc cttacattat
     6541 ccatttttca ggacatgtga aaccgtggag caaggatttt gaagggccaa cgaagaaata
     6601 ttacgaaaaa tatgcaggga tgacggcttt ccgttgtgta gctaaattcc ctaaatatcc
     6661 aaaatatgca aaagttcaac caaaaacaga tgtagttgtt aaataataga agaccacaac
     6721 tgaagagggg gagtaggaat ggaaattaca atgtctaaaa atgcagtaga gacgttaatt
     6781 gaaaaggttg gggaaaatac aaaaatcgca ctcgcgctta tcaatgattc cgatccattt
     6841 ctaagggaca aaggtgcttt tgcaaaaggc agcttttttc aaatcattcc ttttgtttcg
     6901 gaatttggag aatatgcgac taaaatcgag catccattat tggacatcta tacatctaaa
     6961 ttagagcaaa attatttcgg taaacgattg aacatggact tcaacaaaca gcttgacagc
     7021 ttttcattag aaaatgaaat cgcagtactc gattataata tcaaattaaa gaactgcttc
     7081 ttcagctaat agtttcgaga aagtccaaaa aggaggtata cattgagata ctactttgtg
     7141 gatgaagaaa agaatgtaat agaaacagat gaaaaaaaat ataattggct cgtacttgat
     7201 agtgcaaagc ccgaagagat tgagcaagca atcgaagaat tcgagcttcc tgatgatatt
     7261 ttcgtaggaa ccgaatatcc ggaagaagtt tctcggatgg agcgccttta tgagacgaaa
     7321 ctagagcatc cattttcttt ggtagtgatt aatctagatc agtcagataa tcgtatcgaa
     7381 aaaaaattaa cgccaatatc ttttgtactt tccgataatc tcttgattac ttgtatcgat
     7441 agaaaaaccg aatttgtgga tcggctgctg acaaagcatg gaaatcattt aaactcgttt
     7501 gaaaagatca tcacgtatac attattagat atttacaccc attacgtgaa agaactaaga
     7561 gagatgaaaa agcgaattga cgctttggat aaagcagctc gtaaaacaac ggaaaatgaa
     7621 gaactgtata aacaggcaga tcttgaaaga gacatcgtat atatcgatca taccttaaga
     7681 gatcaacggg aaacaatgga tcaattatgg aattctgaaa ctttcatcaa acgtttagac
     7741 gatgaacagc tactctatga tgtccatttg agacagcgac aaacagaaaa aatgatcgag
     7801 atctatcgag atttattaga gagtattggt gatctattca acgggatgat ggacaataat
     7861 ctaaatcata tcatgaaata tctagattca gctgcattaa tcatttccgt tccggcgttg
     7921 ttcgcaggga tttggggaat gaatacagga ggattaccgg gtaaaagttc tgctctaggc
     7981 tttatactcg tagtctttgg ctctttgata gcagcagtag ttttaggtta ccatttatac
     8041 cggaaagatt atacaaatta aagaatctat ttaaaacagg tatcaaacaa agaaatttgt
     8101 tttggcaata caatttaaaa actaggagga atacagcaat gacagaacca aaattaatcg
     8161 acccgcgaaa cttgtaccat acggagaaat ttcctaaaca agatcaggat acaccagctt
     8221 tacagcagaa tatgattcct gttcctgatt gtggagaaga atcctatgaa ggcaataatc
     8281 aactagaaaa ccgccgtgta ctaatcactg gtggagattc agggatcggt cgtgcagcag
     8341 cgattgcatt tgctagagaa ggggcagata tcgctcttca attcttccca ggagaagaaa
     8401 aagatgcaga ggaagtagca aaatacgtga aagatgcagg acgtaagatt gtcttactac
     8461 cttttgatct tcgtgacgaa caagcaccta aagaaatcat agataaagcc gtgagtgaac
     8521 ttggcgggct agatacgatg gtactaaacg caggacagca aatttcttgt cagtctattg
     8581 ctgagttacc acttgagcaa gtcaaagaca catttatgat aaacatcatc gctatgtttg
     8641 ctttagtgaa agaagctgtt ccgcatatcc cagcaggagg agcaatcgta acaacaactt
     8701 ctgttcaagc attcaatcca agcgaacatt tattagatta cgcagcaaca aaagcttcaa
     8761 tcgctaactt tacgatcggt ttagcaaaac agcttgcacc taaaggaatc cgtgtaaatg
     8821 gtgtagcacc tggtccaatt tggacaccat tacaactaga cgaaggacaa ccttctgatt
     8881 cgatccctga atttggtcag caaagtttac tagaacgtgc aggtcagcca ggagaattag
     8941 caccagttta tgttttctta gcatcgaata aagcaagtta tgttacagcc caaatttacg
     9001 gagtaactgg tggagaagcg atcaacttat aagaagttga tcgtttcacc cctatgagga
     9061 ggtgcgaaaa tgaataaagg tgtaaaaacg atcggagtga tcggaacatt acttttgcta
     9121 tctgtgcttt tgtttgcgat actattaagt gcaacctatc cattgccttt tcagctagag
     9181 aagtttcgat tcttttccat cactaattca tacgtgcaac aatatgtatt ttggcttgcc
     9241 gttgcatttg ctattttgac aattatcacg ttacttgttt tcctgtttta tccaaaaaca
     9301 atcggaaact ttctactgaa acatggtgat ggggagttga cgttggataa aaaagcaatt
     9361 gaaggaatgg ttcgttctca cttgcatgaa gatgaattca tccattcacc aaaagtaaat
     9421 gtcaaagcaa cgaaaaacaa gatcgccgtc aatgtaaaag gggagttgaa acgaacttca
     9481 gcactcattg gtaaaacagg aacattgatg aaagaaatcg aaaatgaagt acaacacata
     9541 ttgggaacaa aagagccagt gaaagtatcg gtgaaataca caggctttga agaaccagct
     9601 aaacgaagca atgaccgcaa acgagtagaa taggggggga ccaaaaatga aagaactatt
     9661 ttcgacatac aagctcccta tcatctttgg ggtacttgga ttgatattag ccgttttatg
     9721 gatcaccgtg ggctttttca agaccttatt gatcttgatc atggcagcga tcggcgtcgc
     9781 tatcggtttt tatctgaaac aaacgaaaat cttagatcac tattttaaat cttaggagga
     9841 aacatccatg aataacaata acaaaaataa taacaataaa atgaacaacc aaaaaccagt
     9901 gtctgcacat ccagacccaa cgacaccaaa ccaatcaaat ggtgtgaacg atgaaaagaa
     9961 caaaacagca ccagtatctg cacatccaga tccagtagtc cctaacgttc aacaaggagt
    10021 agaagagaag aaacatgatg cagaaaagca tgcacctcat catccaggaa ctccagaatc
    10081 taaagttcca gaacaacatg atgcaatcga tccttctaaa cctgtggaag agcaaaaaca
    10141 tccttctgac catgcgaaag cacaagaaaa acttagttct gaccacacaa acggacaagg
    10201 aaaacttggt tctgatcata caaataacca aggaaagcat gattctgaac aggaagattc
    10261 aatgcgcggt gagctgaatt atgaagataa agttgtgcaa aaaatcatcg gaatcgcaat
    10321 tgaacaagta gacggtttat tatctgcaaa cggtggtttc ttctctaatg tggcaggaaa
    10381 acttgtgaat acagataatg taacggctgg gatcgaaaca gaagtcggta aaaaacaagt
    10441 agcagttgat atggatgtca ttgtggaata tggcaaagat atcgaaaaaa tctttgaaga
    10501 aatgcaagaa gtaatcggca aagaagtaaa aaatatgaca catttagaag tgatcgaagt
    10561 caacgctaac gtagtggaca tcaaaacaaa agaagaattt gaaaaagatc aagaaacggt
    10621 gcaagacaaa gtaactgacg cagcgaaaaa aaccggtgaa tttgcttcga atcaaacaga
    10681 taaagtaaaa tcagcagctg gaagcggcgc acaaaaagta aaagaaaata cagaaccacg
    10741 ggttcagtaa taaggaagta aaacattagg aggaacgaaa catgggattt atttggtcac
    10801 ttatcgtcgg aggaattatc ggagcaattg caggagcaat cacgaataaa ggttcttcga
    10861 tggggattat tgcaaatgtc gtagcaggtt tagttggatc agcacttggt caagcattat
    10921 taggttcttg gggaccaagt attgcaggaa tggcaatcgt gccatcattg attggtgcca
    10981 tcattttagt actaatcgta tcattctttg ctcgaaaact gtaaaaagac ttttaaaaag
    11041 aggtcgtgaa aaagctgttc ttcatcaagt aataagaaca gccaaacaaa aatagcttct
    11101 catatttttc atttggttgg gcatattatc gaagatgcaa gcttttgaac actgtttata
    11161 cggaataaga ggctgtgaca agacttttgt cacagcctct tatttatgcg ggcaaattcc
    11221 caattagatt tttaaaagtt tttccttaaa tgtgtcttta ttgatacaga gaagcttctt
    11281 taataaaaca atgcctccct aaattttctt gagataggaa aggtgaacat acaaaataat
    11341 acgaccactt tgaaaaccca gatgatccac aaatggatcg tatgatactg atgaagtaaa
    11401 aagcaatgga tcagaaactc aaagagattg aaaaagacaa ggaagaaata atatctcttt
    11461 tttactcttg tctgttttag ccaataatag ctcgtaaagt aatctagaca aacaaataga
    11521 agtaaacaaa gtttcgtaag agcagcaatc gtatcatgtt gctctgctag acgattgacg
    11581 agcaggaaaa atgttggtaa tggaatatag atcacgagta atgaaagaaa aaagtaaaca
    11641 ataaatggca tactattcct cctaattgtg tgagttcgcc ctcattttaa aataacgata
    11701 tttgtttgtg aagctttttc gtgtcgtaac aaatgttatc taatgtattt ttaaataaat
    11761 aatcattatt atcaaaataa t
//
LOCUS       DADVXV010000087        11300 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.088, whole genome shotgun sequence.
ACCESSION   DADVXV010000087 DADVXV010000000
VERSION     DADVXV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.088"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            12..84
                     /locus_tag="KB969_002332"
     tRNA            12..84
                     /locus_tag="KB969_002332"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="KB969_002333"
     tRNA            88..160
                     /locus_tag="KB969_002333"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="KB969_002334"
     tRNA            168..249
                     /locus_tag="KB969_002334"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="KB969_002335"
     tRNA            267..339
                     /locus_tag="KB969_002335"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="KB969_002336"
     tRNA            351..422
                     /locus_tag="KB969_002336"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="KB969_002337"
     tRNA            439..524
                     /locus_tag="KB969_002337"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="KB969_002338"
     tRNA            535..608
                     /locus_tag="KB969_002338"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="KB969_002339"
     tRNA            618..691
                     /locus_tag="KB969_002339"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="KB969_002340"
     tRNA            711..783
                     /locus_tag="KB969_002340"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="KB969_002341"
     tRNA            811..884
                     /locus_tag="KB969_002341"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="KB969_002342"
     tRNA            898..971
                     /locus_tag="KB969_002342"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="KB969_002343"
     tRNA            995..1084
                     /locus_tag="KB969_002343"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="KB969_002344"
     tRNA            1097..1170
                     /locus_tag="KB969_002344"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="KB969_002345"
     tRNA            1189..1264
                     /locus_tag="KB969_002345"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="KB969_002346"
     tRNA            1266..1336
                     /locus_tag="KB969_002346"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="KB969_002347"
     tRNA            1350..1423
                     /locus_tag="KB969_002347"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="KB969_002348"
     tRNA            1448..1535
                     /locus_tag="KB969_002348"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="KB969_002349"
     tRNA            1557..1628
                     /locus_tag="KB969_002349"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="KB969_002350"
     tRNA            1651..1740
                     /locus_tag="KB969_002350"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="KB969_002351"
     tRNA            1753..1826
                     /locus_tag="KB969_002351"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="KB969_002352"
     tRNA            1845..1917
                     /locus_tag="KB969_002352"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="KB969_002353"
     tRNA            1921..1993
                     /locus_tag="KB969_002353"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="KB969_002354"
     tRNA            1998..2068
                     /locus_tag="KB969_002354"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="KB969_002355"
     tRNA            2081..2154
                     /locus_tag="KB969_002355"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="KB969_002356"
     tRNA            2166..2237
                     /locus_tag="KB969_002356"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /locus_tag="KB969_002357"
     CDS             2503..3696
                     /locus_tag="KB969_002357"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBB6870288.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="KB969_002358"
     CDS             3826..5298
                     /locus_tag="KB969_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6870289.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="KB969_002359"
     CDS             5381..6169
                     /locus_tag="KB969_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBB6870290.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="KB969_002360"
     CDS             complement(6236..6904)
                     /locus_tag="KB969_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBB6870291.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="KB969_002361"
     CDS             7019..8731
                     /locus_tag="KB969_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870292.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="KB969_002362"
     CDS             8734..10506
                     /locus_tag="KB969_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870293.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(10588..>11300)
                     /locus_tag="KB969_002363"
     CDS             complement(10588..>11300)
                     /locus_tag="KB969_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6870294.1"
                     /translation="TGMIFKFANRRYGLKYNPVNGVSLARKPKTNEEIKKEKDGYLSK
                     EEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELISLTESDYDGNKITVSGTYDYE
                     LKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIKNNKDKYIFISKNGNPISIQAY
                     NQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPLKAIMDRVGHEDSKTTLKIYTH
                     TTKNMQNQLVEKLGKIEI"
BASE COUNT         3252 a         2024 c         2555 g         3469 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggcagaaaag gggcaattta aatttctatt tttcctagtt tttctactag
    10621 ttgattttgc atatttttag ttgtatgagt ataaatcttt aatgttgttt ttgaatcttc
    10681 atgtcctaca cgatccataa tggcttttaa tgggattcct aattctgtaa gtagagaaat
    10741 gtgggaatgc cttaacatgt gagaagaaac ttttttatct aggtttaatt ctttggatac
    10801 tgctcttaaa gattgattat atgcttgaat agatatcggg ttaccatttt tagagatgaa
    10861 aatgtattta tctttattat tcttaattaa tttgttttct tcaattaatt gatctatgat
    10921 ttctttagca ttacttgata attcaatggt tctataagaa cctgtatttt tagttgttgt
    10981 tttaattttt aactcgtaat cataagtacc agaaaccgta attttattac catcataatc
    11041 agattcagtc aaagatatca attcaccata acgtagtcca gttaaaaaca aaaatttagt
    11101 aattaaagaa taacgtgact gttgatgtga acttttttgt ttactagcaa tcatttgaac
    11161 ttcttctttt gataaataac catctttttc tttttttatt tcttcgtttg tcttaggttt
    11221 tcttgctaaa gaaaccccat ttacgggatt atattttaat ccatatcgac ggttggcgaa
    11281 tttaaaaatc attcctgtaa
//
LOCUS       DADVXV010000088        11123 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.089, whole genome shotgun sequence.
ACCESSION   DADVXV010000088 DADVXV010000000
VERSION     DADVXV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.089"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            85..1344
                     /gene="lysA"
                     /locus_tag="KB969_002364"
     CDS             85..1344
                     /gene="lysA"
                     /locus_tag="KB969_002364"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBB6870295.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1331..2131
                     /gene="dapF"
                     /locus_tag="KB969_002365"
     CDS             1331..2131
                     /gene="dapF"
                     /locus_tag="KB969_002365"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBB6870296.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2134..3015
                     /locus_tag="KB969_002366"
     CDS             2134..3015
                     /locus_tag="KB969_002366"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBB6870297.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3012..3728
                     /locus_tag="KB969_002367"
     CDS             3012..3728
                     /locus_tag="KB969_002367"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBB6870298.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3734..4429
                     /gene="dapD"
                     /locus_tag="KB969_002368"
     CDS             3734..4429
                     /gene="dapD"
                     /locus_tag="KB969_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBB6870299.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4445..5446
                     /locus_tag="KB969_002369"
     CDS             4445..5446
                     /locus_tag="KB969_002369"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBB6870300.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5443..6804
                     /locus_tag="KB969_002370"
     CDS             5443..6804
                     /locus_tag="KB969_002370"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBB6870301.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6764..7915
                     /locus_tag="KB969_002371"
     CDS             6764..7915
                     /locus_tag="KB969_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBB6870302.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7890..9059
                     /locus_tag="KB969_002372"
     CDS             7890..9059
                     /locus_tag="KB969_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6870303.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9234..10613
                     /locus_tag="KB969_002373"
     CDS             9234..10613
                     /locus_tag="KB969_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6870304.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10894..11123
                     /locus_tag="KB969_002374"
                     /pseudo
     CDS             10894..11123
                     /locus_tag="KB969_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3702 a         1945 c         2493 g         2983 t
ORIGIN      
        1 ttaatattat tccaataaaa ttcaaatctt tatcaaatga aattccaata aaaacggaaa
       61 aaaagtgaaa agaggaatga aaaaatgaca gaattgataa ttggcggagt cacagcaagc
      121 acattggcag aaaagtataa gacacctctg tatgtgtatg atgaagaaaa gatgagacaa
      181 acgatgctgt cattcaagcg aggctttgta tcgaaacgtt ttgatacaaa agtgctttac
      241 gcctctaaag cattccaaac gattgagatg ctgcatttag ttcgtgaata tggattcggg
      301 ctagatgttg tcagtggtgg ggaaatctat accgctttgc aagctgattt tcctagagat
      361 actatctact tccatggtaa caacaagacg ccagaggaac tgatctatgc acttgaaaat
      421 gatttgttgc atattgttgc cgataatttg atggaagttg aattattagc agaattaagc
      481 caacgctatt taaaaaaaat ctgtatcatg cttcggttga atgtcggagt agaagcacat
      541 actcatgaat atatcgtcac tgcgcatatt gattcaaaat tcggcatgag ctatgaaagt
      601 aaagagtgcc aacaagccct tcagttgata aaagaaagca gctatctaga gttagaagga
      661 tttcatgctc atatcgggtc acaaattttt gatgttactg cttggttagc tgaaatcgac
      721 aaattgacga attacttaac cgattttgac caacctcttt ccttgaatct tggcggaggg
      781 tttgggattc gttatacaca aaatgatcag ccgatcccag tcgaagaggc actaaaaaaa
      841 ctgattgaat atacggaaga agctttggaa aaacgaaaac tgaccattcg tcaattactg
      901 atcgaaccgg gtagaagtat tgttggagaa gctggtacaa cactatacac gattggtttc
      961 atcaaaaaga caccacataa aaaatattac tttgtagatg gcgggatgac agataatatc
     1021 cgtccagctc tgtatcaggc agaatacgat tgtgatttag cagcaaaact gtcggaagaa
     1081 aaaacagaga aagtgacgat tgcaggaaaa atgtgtgaat caggcgatgt ggtaattaaa
     1141 gaagcttatt tgccgaaagc agaatcgggt gatcttttag ctgtttattc cacgggagct
     1201 tatggatact cgatgagcag caactacaat cgagcgacac gaccagcagt tgtttttgtc
     1261 aataatggcc aatcaagact gattgttcgc agacaagcat tttctgatct actaaggggg
     1321 gaagtttcct atgatccttc ataaatataa tggctgcgga aatgatttta tcttattaga
     1381 ttacgcagaa gacacagatt atagtcaatt agccgcttct ttatgcacaa aagaaaaata
     1441 tgatatagac ggattgatcg ccgtaaaaat cgatccgttg gaaatgatct attacaacaa
     1501 agatggcagc cgcgcgccga tgtgcggaaa tggcattcgc tgttttgctc gatacgtaaa
     1561 tgatcagaac atgatgaatg aacaggaatt caacgtagag acattagcag gcacaagaaa
     1621 aattacggtg ttggatccct caccttttta ttgcagcgta gatatgggag tgccagatga
     1681 ttctccggaa aaaatcaaag ctaatcaaac ttatccaata aaaaaccagg aaatagagat
     1741 caatggtgaa aaagtaacga tcactagttt atttttagga acgattcata ccgttgtttt
     1801 tgttgaaaat gcgcgtgagg aagtctggag aaaaagaggt gaactgatct gtcatcatcc
     1861 tttgttcaaa gaaaaaacca atgtcaactt tgtagaagta gtcaatgaac aagaattgat
     1921 cgtccgtacc tatgaaagag gagtaggttg gacacttgct tgcggtacag gttgctgtgc
     1981 ctcttatgtg gttgctaagg aaactgggaa aatttcagca gatcaggtag ttgttcactt
     2041 ggaacaagga gacttgatga tctctggtga ggatgcgata caaatggctg gcccagcagt
     2101 tcatgaatgg acaagaatat tggaggaatg aagatgataa aaggttcgat cgtggcgctg
     2161 atcacgccga tgaatgaaga gggatcagta gattatgctg gtttggaaaa attgatccaa
     2221 ttccatttag atgaacaaac agatggatta ttagttttag gtacaacagg agaatcttct
     2281 acgctcacac aatctgagga ggagcagatc cttcaactga cagtaaagaa agtggctggc
     2341 cgtgtgccgg tgattgcagg agctggaacg aataatacga aagaaacgat tgaaaaagcg
     2401 aagcattttg cttctttggg ggcagacgca cttttggtca tcacccctta ctacaacaaa
     2461 acaagtgatg caggactagc tgctcatttt acagcaattg cagaagcctc accgattccg
     2521 cttattttgt ataatgttcc ttctagaaca ggcatgtcga ttccaatcca tgtattagta
     2581 aatttagcag aacatcctaa tatcattggt ttgaaagaag cctcaggaga tatggcttat
     2641 gtgatggatg ccgctcggtt gattggagaa gaattcttcc tttacagtgg aaatgatgat
     2701 ttgatcctac cagtaatgag tgtaggagga agcggtgtaa taagtgtatg ggcgaatatc
     2761 caacctaaaa tagtccatga attagtaaaa gatacgcagg acggaagatg gcagcaagca
     2821 aaagaaaagc aattaaatgc acttgaactg atccatgcct tgttcagtga gaccaatcct
     2881 attcctgtca aagcagccat gtcattatta gacttacctt ccggacctct acgcctgcct
     2941 ttagtttctc tttcaaaaga gaaaaagaaa caattagctc agcttttgtt aaaagaaagg
     3001 acggttgaaa aatgaaaatc ggactgattg gcagtggaca gatgggaaat agagtcgaag
     3061 aagttgcaca agaaagagga gatacggtcc ttcttttacg gacggcacct aaagaagcaa
     3121 ctacgcttgc ttttacggaa ctgccagaac tgcttattga tttttctcat ccagataatt
     3181 tagagaaaat cctttcgtat agcttatcat atcaacttcc gttagtcatt ggcacgacag
     3241 gttatacaca atcacagttc caagaaataa aagaacatgc caaacatgta cctgtgatgt
     3301 atagtgctaa tttttcgttc ggcatcatgg tgatgaatca actaatcaag caagcagctg
     3361 caatgttgca aggctggcag atcgaactga ttgaaaaaca tcatagtcgt aaaaaagatg
     3421 caccatctgg tactgcaaat atgctgcttc aaacaatcca agaagtgcaa aagctgcagc
     3481 ccgtatacaa ctggcaaggg aaaaaaagag aagaaaacca aattggtgta cacagtattc
     3541 gtgcaggttc tttacctggt gaacatgatg tattgtttgc tgctactgat gaaatattta
     3601 cgatcaaaca tgaatctttt tctaatcgaa tctttgctgc aggcgcagta gaagcagcgg
     3661 actggttgaa agatcagtca ccaggttatt acaaattaga agatttatta atggacaaag
     3721 gggtgtaaaa aacgtggaag ctcaagaaat catccgctac attcaaacgg catctaaaaa
     3781 gacgcctgtg aaagtctatc tgaatgtaac cgagccaatc gaatttaaag aaagtaaagt
     3841 ttttggtgaa ggaagcagct tcgttgtttt tggtgactat gagacgattg ctccggtttt
     3901 agaagctgaa tcagaaaaaa tcattgaaat cgaaatcgaa actgctgcaa gatacagcgc
     3961 agttcctttg ctagatatta aaaaaattaa tgctcgtatc gaaccaggtg ctattatcag
     4021 agatcaagtg tcaatcggca acaatgccgt gatcatgatg ggagcgatta tcaatattgg
     4081 tgcagtaatc ggtgaaaaca cgatgattga tatgggtgct gtcttaggtg gacgagcgac
     4141 agtgggcaaa aactgccata ttggtgcagg agctgtctta gcaggtgtga tcgaaccagc
     4201 atcggccaaa ccggttatcg tagaagacgg cgtactggta ggtgcgaatg cagtgattgt
     4261 tgaaggtgtc catatcggaa aagatgcagt cgtggcagca ggagcagtgg ttttagaaga
     4321 tgtggcagca gaaactgttg tcggtggaat acctgcacgt gtattaaaaa taagtgatga
     4381 tcagacaaaa gaaaatacag cattgattgc tgcgttacgc gaattataga ggagatggag
     4441 aaaaatgcgc gaaatagata cctgtattgt gggggcaacc ggattagtcg gccaaacgat
     4501 gctcaaagtg ttagaagaat atgattttcc agtaggacga ttgaaattat tagcttcaaa
     4561 acgttcagcc ggtaaagttt gtgtattcaa gaaaaagaaa cacactgtac aggaattgac
     4621 agaaacttca tttgaaggat atgatttagc gctattttct gcaggtgctt ctgtatccaa
     4681 agagtttgcg ccaatcgcac gaagtcaggg actatttgtc atagataatt cctcagcatg
     4741 gcgggaagat tcggatattc cattaatcgt tccagaggtc aatctggaag actatacatt
     4801 gaatcggctg attgcaaatc caaattgttc aaccattcaa gcggtacttc cgcttaaagc
     4861 tttacaagaa gcctttggta tccagcgagt caattattcg acctatcaag cagtttctgg
     4921 ttccgggcaa aaaggcattg aagatcttca tcgtacgcaa aatgacgagg aaccagtttt
     4981 gtatccttat aatattagcc aaacggtgat tccggaaatc gatcagcctt tggaaaatgg
     5041 gtatacaaaa gaagaacaga aaatgataaa tgagacccgt aagattctgc atcagcctgc
     5101 tttgccagta tcagcaacct gcgtacgtgt gccaatcgaa aatggacatg gagtctctgt
     5161 ggcagttcaa ctgcaaaaag agtttacgac ggaagaaatt agagagtgtc tcagccagtt
     5221 tccagggatt caattagaag atgatctagc agcacataaa tatccgacga gcattcttgc
     5281 tagaggaaca gatatggttt atgttgggag gatcagaaaa gacacttctt tagagaacgg
     5341 attgttgttc tatacgactg ccgataacat acgcaaagga gccgctgcga atgccgtaca
     5401 gattgctgca gctttaatgc agaaaatagc ggaggtggca agatgagtaa tacgctgaaa
     5461 gtagcgaaat tcggcggaac atcgatgtct catgaagagc aattcaaaaa agtccgtaca
     5521 attgttcttt cagatcccaa tcgccaagtg atcgttgttt ctgctttagg caaacgtacg
     5581 tcagatgatg acaaagtaac agacttactt tatttgattt atgcttacct tcagcatcat
     5641 gttgattgga cacccctttg gaaaaggatt tgtgatcgtt tcattcaagt aagagatgtt
     5701 cttgccctgc agttacctat tgaagatgaa ctagcacgca tacagaaaca actggaagac
     5761 gaaaagataa ctgaagatta tttagtaagt agaggtgaat atctgactgc tcaactgatg
     5821 gctgagtatc ttggttacca gtttattgac gcaaaagacc tgattttctt tgactatgat
     5881 gggaaaatcg atcaggaaaa aacagcacag gaaatcacaa aagcatttaa aagatatccg
     5941 aaaatggttg ttccagggtt ttacggggcg aaccctgcag gaaaagaaaa attattgggc
     6001 cgtgggggaa gcgacattac cggcgcgata ctggcgaaga tgttgcaagc ggaaagttat
     6061 gagaattgga cggatgtttc aggaatcatg atggctgatc cgcgaatcat cgatcatcct
     6121 aaaatcatcg aggaaatctc ttttagagaa ctgagagaga tggcttatat gggggctaac
     6181 gttcttcatg aagcagctgt tttcccagtt caagaggctg atatccccat ccaaataaaa
     6241 aataccaatg atcctttcgc tcaagggaca aaaatatcga atcacgaaat agaaaaggaa
     6301 aatggactga caggaatagc tggacgcaag gattttcttt ccatcacttt attcaaacgt
     6361 catatgtccg atgaaatcgg gtttatctgg aaagcaatga gcatttttgc taaacatgag
     6421 atatcaatcg aacatattcc ttcagggatc gacaatatcg gagtgatcgt ctcagcagaa
     6481 gcgattgccg ataagttatt tctcatcacg aaagaattaa aagaaacact tggcgtggaa
     6541 gaaatcgtcg tgatcgaaga cttagctttg atctctgtcg ttgggggtcc gcataaagaa
     6601 ttgattggat tatctgggaa agtgttatcg atattgaaca aattagaaat tcgcacatcg
     6661 atcttatcac aaggagcaca ggagttgaat ctgatcatcg gtgtaccgaa taatcaatat
     6721 gaaacagtag tgaagggtat ctatgaaggg atggtgaata cggatgctga aagaatatcg
     6781 aatggcactc catcaaattc ctgaaatcgg gtttcatgaa ttcaagacaa aaaaatattt
     6841 atatgaacaa gtaaaaaaca gcgaggccgt tatccatgaa atcggcgaaa caggactact
     6901 cctttatttt gataatcagc aagaagaaac gattgctttt cgaacagata tcgatgcact
     6961 gccagtcaaa gaagaaacga atctctcttt tgcttctaag catgaaggtt atatgcatgc
     7021 atgtggtcat gacggacata tggcgatgct tttagggttg actgacttta taactaaaca
     7081 cattgaggat cttatttata atgtagtact gatctatcag ccatcagaag aaatttccgg
     7141 tggcgcacaa agcgttattc agtcaggatt gttggataaa tatgaagtac aagcaatatt
     7201 tggctttcat ctatggcctg gactagctaa gggagaagtt ttctctcgac caggaccttt
     7261 gatggcacaa agcagtgaaa cagacattat cattaaaggc cagtctgcac atattgcttc
     7321 tagtgaaaaa ggaatcgata gtctggaggc agctgtacga tttttgaaga atgtttatga
     7381 ttttgaccgg caattaccgg cagagtggaa tcatctaatg aaatttggcc aaatccaagg
     7441 tggaacgatc cgaaatgttt tagctggaga agttattgta tccggaagta tccgttctta
     7501 cagttcagat atgcaaaatt atttgaagag gggattagac catttagcag aacagtttca
     7561 ctctacagct actatttctt ttcgctataa tgacggctat ccagctgtaa tcaaccatag
     7621 aggcttatat gcagcactgt tagattcaaa caaactacat gaattagatg ctccagttct
     7681 tcaagccgaa gattttggca tatatacgca acaatatcca tgtgtatttt tctttttagg
     7741 tgtcggtgat acccctgctt tacatgatcc gacgttcgat tttgatatgg atgttttaga
     7801 aaatggtgta gaatggtaca aaacgattct ttttacagaa aatcttcttg taaaaatcga
     7861 tagcagttca aaagaggagc gagtaaataa tgatgaattt atccaatcga tttagtccta
     7921 ggctttctag aatagaagta tcaaaaatac gacaattcga tcagcaaata tcgtcgatac
     7981 cagatgtgat caaactcacc ctgggagaac cggattttcc aactcctgaa catgtcaagc
     8041 aagcaggaat agcagcgatt gaagaagact tttctcacta taccggaatg agaggattag
     8101 aggaactgcg ggaagcggct tgtatatttc agcaacagcg ttatggatta acttatgatc
     8161 cgcaaacgga agttttgacg acagttggtg caacggaagc gattgcctct gcgttgttat
     8221 ctgttttgga agaaggagac aaggttctta ttccagcgcc tgcttattca ggatatcagc
     8281 cattagtgga actagctggt gctgaattga tcccgataga tacttctgac acagggtttg
     8341 tctgtcagcc ggaacaattt gaacgagcat ttgaacaata tggatcagct gtcaaagcag
     8401 tcattttaaa ctatcctaac aatcctactg ggacgacatt gtctgcaaaa caattgaaag
     8461 caatcgctga ggttttaaaa aaatatccgg tatttgttat aagtgatgaa gtatatgctg
     8521 aattgactta tagtggaacg catatgtcca tagctactta tcttccagaa caaacaatcg
     8581 tgataagcgg gttatccaag tcacatgcga tgactggttg gcgagtgggc tttatttttg
     8641 ctcaaaaagc ccttattgac gaactaatta aagtccatca atatctggtg actgccgcta
     8701 caacgatgtc gcaaaaagct gcggctgaag cgctaataaa tggggtgaaa gatagcgaga
     8761 atatgaaaga gcaatatcaa acacgaagag actatctggt ccagcaattg gcgcctttag
     8821 gatttgaagt gacccagcca aacggtgcat tttacttgtt ttgcaaactc ccagctgcca
     8881 ttcaaactga ctcttggcag ttttgtgtag aattagcgga acaggcaaaa gttgcgtgta
     8941 tcccaggaat tgcatttggc ccagaaggag aaggttatat ccggatttct tatgctagca
     9001 gcatggaaaa attacatgag gcctgcaaac ggatcaaaga ctttttaaca gaacagtgat
     9061 tcatagattt tatcaaaaaa acaatcgtta attttgcggt atattctgca aggagacgat
     9121 tgttttttaa atttagttca aatgaacgcg tttcttttga ttcataacta atgtaatgtt
     9181 aagtttaaat tgtttagaat gattttaaaa gaatattcaa ggaggtttca tcaatggaaa
     9241 aaatcaaagt tgtcattgta ggtgcatctc atggagggca tcaatcgatc ttggaactat
     9301 tgacacgata cggtgaaaat gtagatatca cgctatttga agcaggagac tatatttcct
     9361 tcatgtcatg tggtatggag ctgtatttag aagacaaggt aacagatgta aatgatgtac
     9421 gtaatttcag accagaaaac tttccgcaat ccaatgttca tattttaaat aatcacgaag
     9481 taaaaacgat cgatgccgat aaaaaaacag taacggttac tagcgcatca gataacgaaa
     9541 caaaagaata tccttatgac aaattgattt tgagttctgg tgtcaaacca aacaatctgc
     9601 cagtaccagg agcagatcta gaaaatgtct acttgatgcg tggatacaat tgggcaacca
     9661 aaatcaaaga aaaattaaat gatccggcta ttaaaaaaat cgctgtcgta ggtgcgggtt
     9721 acattgggat cgaagcagca gaagcaagcc gaaaagctgg gaaagaagtc gtattgcttg
     9781 atgtgatcga tagaccttta ggcacttatt tagatgctga gatgacagat attttagaac
     9841 aacacctaaa tgaaaacggt attgaagttt tgacaaatgc aaaaatcgaa gcttttactg
     9901 gtaacggaaa agttgaggca atcaaaacaa gtgaaaaaga aatcccagca gatctagtca
     9961 ttcaagctgc cggtgtgaag gcaaatacag aatggttaaa agggatcgtc gacttagatg
    10021 aacgtggctg gatccaaaca aatgaatact tgcaaacgaa tcttccagat gtgtatgcag
    10081 taggagatgc tacacttgct tattctatcc cagcacgcaa aaaaatgccg atcgctttag
    10141 cgactgttgc acgtagagaa gcacgttatg tagtaaaaca tctttttgaa gaagtaccaa
    10201 acaaaccgtt cggcggagtc gtaggttcct ctgcattaag tgtctttgac tatcattttg
    10261 cagcaagcgg attgaatagc tttacagcag caaaagcagg agtagatgta cgagtgtctt
    10321 attatgaaga tacgttacga ccaaaatatg taccagaaga acaaggaaat ccaaaagtgt
    10381 ccatccaatt attctcggat ccaatgaccc atcaattgct aggaggagca gtattatcta
    10441 cctatgatgt tacaggtcaa ggaaatgtat tggcactagc gatccaaaac aaactgactt
    10501 tagaagaact agcagaagct gacttcttct tccagccagg ctttgaccga caatggagca
    10561 tgttgaatct agccgctcaa caagcgttag gagaagaacc atttgtagaa taagaaaacg
    10621 aaatatttga aaagaggttg tgaaaaagct gccttgcatc aagtaataag aacagccaag
    10681 taaaaacagc ttcttatgtt tttaacttgg ctggacttat taccgcagat gcaagctttt
    10741 gaacaccgtt tattttcaaa aaagggactg tgacacgatt tgtgtaccga cccccaaaag
    10801 ttagaccaaa aaatctaact tttggaggtc ggtatttttt atggttaaat atacttttga
    10861 acttaaatta aagatcgttc atgattattt ggatggcaaa ggcgattgga ccgtaaaaat
    10921 ccagatcaag agattgaagc ggaaatgctt aaaattcggg agaagcacaa ggattatggc
    10981 tgtttacgga tgaccaatga actaagaaac cgcggtttct ctatcaataa aaagaaagtt
    11041 cagcgcttga tcaagaagct aggaataaaa gtaacggcat acacgcgtaa atcacgtcgc
    11101 tacaattctt atcgaggaaa agt
//
LOCUS       DADVXV010000089        11048 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.090, whole genome shotgun sequence.
ACCESSION   DADVXV010000089 DADVXV010000000
VERSION     DADVXV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.090"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            270..539
                     /gene="rpsN"
                     /locus_tag="KB969_002375"
     CDS             270..539
                     /gene="rpsN"
                     /locus_tag="KB969_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBB6870305.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            554..733
                     /gene="rpmF"
                     /locus_tag="KB969_002376"
     CDS             554..733
                     /gene="rpmF"
                     /locus_tag="KB969_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBB6870306.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            765..1142
                     /locus_tag="KB969_002377"
     CDS             765..1142
                     /locus_tag="KB969_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870307.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1163..1312
                     /gene="rpmG"
                     /locus_tag="KB969_002378"
     CDS             1163..1312
                     /gene="rpmG"
                     /locus_tag="KB969_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBB6870308.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1336..2319
                     /locus_tag="KB969_002379"
     CDS             1336..2319
                     /locus_tag="KB969_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBB6870309.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2349..2471
                     /locus_tag="KB969_002380"
     CDS             2349..2471
                     /locus_tag="KB969_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6870310.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            2489..4012
                     /locus_tag="KB969_002381"
     CDS             2489..4012
                     /locus_tag="KB969_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBB6870311.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            4036..4275
                     /locus_tag="KB969_002382"
     CDS             4036..4275
                     /locus_tag="KB969_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870312.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(4468..4929)
                     /locus_tag="KB969_002383"
     CDS             complement(4468..4929)
                     /locus_tag="KB969_002383"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6870313.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5124..5342)
                     /locus_tag="KB969_002384"
     CDS             complement(5124..5342)
                     /locus_tag="KB969_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870314.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            5460..7076
                     /locus_tag="KB969_002385"
     CDS             5460..7076
                     /locus_tag="KB969_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBB6870315.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKKIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(7317..8657)
                     /locus_tag="KB969_002386"
                     /pseudo
     CDS             complement(7317..8657)
                     /locus_tag="KB969_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(8933..9088)
                     /locus_tag="KB969_002387"
     CDS             complement(8933..9088)
                     /locus_tag="KB969_002387"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBB6870316.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(9384..9716)
                     /locus_tag="KB969_002388"
     CDS             complement(9384..9716)
                     /locus_tag="KB969_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870317.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(10230..10421)
                     /locus_tag="KB969_002389"
     CDS             complement(10230..10421)
                     /locus_tag="KB969_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870318.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(10515..10901)
                     /locus_tag="KB969_002390"
     CDS             complement(10515..10901)
                     /locus_tag="KB969_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6870319.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
BASE COUNT         3664 a         1752 c         2140 g         3492 t
ORIGIN      
        1 aaaagctact taaaacggta tttgtgtttg attggactaa taaaagtgaa ttcttatttt
       61 tcagagccta aactgcatat tcttttaaat gatttgatta tctctatgta ccgataaatt
      121 cgttttcaaa tagttatcta ttcatatgag ttttatttca tgttatttat tgttgacaag
      181 agcaactctt gttggtaaag tatcagtgtc aaaacgtaac gattacgatt tgaggtgtct
      241 aaatcaaaat aaaaggagta taaaggtata tggcaaaaaa gtcgaaaatt gctaaagcaa
      301 agaaacaaat ggcgatgatt gaaaagtatg cagataaacg tcaggaatta aaagccgcag
      361 gagatcgcac cgctctcgct aaattgccaa gagattcaaa tccgaatcgt ctgaggcttc
      421 gtgatcagac ggatggtcgt ccaagagggt atatgcgaaa gttcggtatg tcccgtatta
      481 agtttagaga acttgcccat caagggttga ttcctggagt aaaaaaagca agttggtaaa
      541 aggaggaaat atcatggcag taccagcaag aaaaacatct aaggcgaaga aacggttaag
      601 aagaactcat caaactgtag taaaaccaga aatttcattt gacgaagcga atggtgatta
      661 tagacgtagc catcatgtat ctttaaaagg gtactataat ggaaagaaag taattaaagg
      721 agcttcaaaa tagtttaata tataactttt aggagggaat caaaatggaa attatttacc
      781 cacctttagt tgaagaagga ttaaagtatt atcttgaaac gacccagcaa tcgctagata
      841 aatgcacttt ttatcgttcg atggtagaga gaggaattat tactgaaacg ggtttaccga
      901 cccaacaggc aattgaaaat ggattagtca aagattacta tgaggaccaa ggcttatcat
      961 ttgatgattt tttaagaatc tatccaattt ttgaagagta tgacgaggag ttatttcaat
     1021 gtatcgatgg ttattgggag atacctgttg atatgaaaga aaatttagtt tcacaattgg
     1081 aatctggcga gttaactttt gaagatgcac aacaaattca agcatatctt gaagatcgat
     1141 aagtattgaa ggaggaagat ttatgcgtca aaatattatt ttggaatgtg tcgaaactgg
     1201 agaacgtctg tatctcacca gcaaaaataa acggaataac cctgaacggt tagaattaaa
     1261 aaagtattcg ccaaaattgc gcagacgggc aatttttaaa gaagtgaaat agctaagtgg
     1321 taaaaaggtg acaaaatggg cataccagtt acaatcgttt ctgggttttt aggggctgga
     1381 aaaacaacgc taatcaatca agccttgcaa gtctcaccct accccaggga agaaattatt
     1441 ataattgaaa atgagtttgg tgaagttggg attgatcaca aattattagt tcatagcgag
     1501 gaacgggtgt tacaactaaa taatggatgt atgtgttgca gtcttcgcag tgatttatta
     1561 gcaatattga tttctttact ggaaacaata gaagaacatc aacaaccaat ttcacaaatc
     1621 atcattgaaa ctacaggtat agcagatccc caaccaatca ttcaaacact tttaacagcg
     1681 cctcaactaa gaggaagagt atatatcgat agtttattga ctgttattga tagtgacagt
     1741 tttgaactta ttgaaagaga accacaagcc cttaagcaac ttgtcatggc agatcgcatt
     1801 tttgtgtcta gaaaacaaaa cttgaattta tctgcactaa aaaaattaca gagagaaatc
     1861 aaaagtatta accctttatc cgatattcga atgttcacac atagtgaaac gattcaaaaa
     1921 aaggattttt ataatttgaa aaaatttaat catcccttag tttttgaaag tgattcatca
     1981 gaaaatcact ataatggcaa atactatcat caacaccatc aagtacatga gtttaaatca
     2041 attctcttaa cttcagatca agacataaaa aaagattttt tactccaatg gattgactgg
     2101 ctgattttaa ccaaccaagg gagcctgtat cgttttaaag gattgattgc tttacaagag
     2161 caggatttta tagttgccat gcaagaggta aacgaacagg ttaattttca atacaccact
     2221 cgacaaaaag accaaaccac tattattcta atcggaaaaa tgttggatga agaaaggatc
     2281 aaacagagtt ttgataaatt actggcggaa agcaaataat gataagtagt gattgggggt
     2341 aatttctaat ggagaaaacg gatatatcta gtgcatatcg acgacttaaa agcccgaata
     2401 ttaaaactag aaaaagggca ttaaaaatta tcaaagaaca taaacgaaat aaaatgaaga
     2461 aattagcata attaaggaag gaaaaagaat gaagaaaatc agtgtaggac ttattgggat
     2521 agcagctcta ggattattgg gagcttgctc cagcactaat gatgcaaaag tatcgaatga
     2581 taaagatgga aaattagaaa ttgtaacaac attctatcca atgtatgatt tcaccaaaaa
     2641 catcgtcggc gatgaagcga acgtggattt aatggttcca gcgggatcag aacctcatga
     2701 ctatgagccc tcagctaagg atatggcaaa agctcatgat gctgatgttt ttgtatatca
     2761 taacgaaaac atggaatcat gggtaccaaa agctaaagaa agttggaaga aagctgggcc
     2821 taatgtagta gaaggaacaa aagacatgat tttattgcca ggtagtgaag aagaagatca
     2881 tgatcacgga gaagaagatc accatcatga actagatcct catacgtggg tttcacccaa
     2941 aatggcaatt aaggaagttt caaatatcaa ggatcagtta gttaaattgt atccgaaaaa
     3001 agcaaaagta tttgagacaa atgctgaaaa gtatttgact aaactgaaac ggttggatgc
     3061 tgactatacc actagtctta aagaagcgaa acaaaaaagt tttgtgacgc aacacgcagc
     3121 ctttggatat ttagctttgg attatggatt gaaacaagtt cctattgctg gactaagtcc
     3181 tgaagaagag ccatcttctg gtcgattagc tgaattaaaa gagtatgtta aaaaaaataa
     3241 gatcaattat atttactttg aaaagaatgc taatgataaa attgcaaaaa ctttggccaa
     3301 cgaagctggg ataaaattgg aagtactgaa tcctcttgaa agtcttacaa aagaacaaat
     3361 ggataatggt gaagattatg tttcagtaat ggaagacaat ctaaaagcgt tagaaaaaac
     3421 aactatggtt gctggtgaag aggtagttcc agaaaaagaa gcgaaggatg aaaagacagt
     3481 tgctaatggg tactttaaag atgccgatgt gaaggatcgc gaattgagtg attatacagg
     3541 cgaatggcaa tctgtttatc cgttgttaaa agatggaatt ttggatgaag ttttcgatta
     3601 caaagcaaaa atcaataaag acatgacagc tgccgagtac aaagattatt atactactgg
     3661 ctataagaca gatattgata ctatcaacat taaagacaac accattgatt ttgtagtcaa
     3721 cggtgaacat catcaataca catacaaata tgttggatac aaaattttga attatgaaaa
     3781 aggaaaccgt ggtgttcgtt ttaattttga aactgatgat gcaggtgctg gtcgttttaa
     3841 atatattcaa tttagtgatc atggaattgc accaagtaag gcagagcatt tccatatttt
     3901 ctttggtgga gaaagtcaag aaaaactcta taatgaattg cataattggc ctactttcta
     3961 tccagcttca ttgtctaaac atgaaattgc tcaagaaatg atggctcatt aaaattcaat
     4021 ttttggagga aatacatggt aagaaaagta ttattgtcta tggattccaa gaatattgat
     4081 gcttatcggc gttatcgatt tgcaaagcaa atgagattaa atgggagtac attagctgat
     4141 attgctgcaa ctttacatgt tagtattgac acagttcata gagtattaaa acgggatcct
     4201 gattgttgtt ttatcaaggt caatactgga agaagtagac gtttagcaaa acggcataat
     4261 agcttggcca attaattgat aataccagag tagatcattt ttcccttatt tggatttgat
     4321 ctgcttttta ttatgtcttg aattgtcaaa tcaagcgcaa cactttatca aagaagactt
     4381 cataaggtgt tctccaatct aaacactttc taggtctgtt attcagtttt tcaatcatct
     4441 gatttatcgt tgagttatct accgtagcta tctctttcga ttttggcaag tattctcgaa
     4501 tgagtctatt cgtattttaa tttgttcatt gttgccaagg gcatgaggat ctggaaaata
     4561 aaagggcata ttattcaatg cttctgtaac tgcgaaatga ttggagaatt cttttcctct
     4621 atctggagtg atcgttttga ccgcctcatt tggaatactg cttaaaagtt caatcatttt
     4681 ctcgctcaca taagcggctt tctttctggg gaccttcttt cctgctaaaa ggaagcatga
     4741 ttttctgtct gtcaaagtca ctaaacaagt accaccagtt ttgccagcta caatatcggc
     4801 tttccaatga ccaaaatcac ttctatcatc tgcggatttt ggacggccat ggatcgaatg
     4861 agtaaggcaa atctttccac gagactcgac atgatttttt gtatgtcttg tttttcctcg
     4921 atggtgcaat gaacggatca ggcctttatt gccgtgtgag aggggttctg tatcgaaaag
     4981 atcattgcaa attgcacgtt agatcgtgat aaaactaatt gaaaagtcca tatgttcatg
     5041 cttcaaacga ttcgagattt cctctggcga ccactgaaaa tcgacaaata aatgacgaac
     5101 aattgaccaa actcacggat catttagaat gtgataacgt ccgcattttt ttcttcgata
     5161 agcataattt ttttccgctt tggaaggtga atagtttttt tcttgtttct tctcagttca
     5221 tgtaaaatag taaacgggct atgctgaatg tcgttgccaa ttatactaat agaaaatcct
     5281 tcttcgtgaa gcagaaagat tctttctcgt tcgagtatag taagatgacg atactggctc
     5341 ataattattt tccttctagg agtgttctcg acaaacttat actagttgga tatcgattat
     5401 gactcatttt tatgtgttgc acttaaagtg taaattcaag gtatagaaag aggttcccta
     5461 tgaaaaaaat acctattaca atcttaactg gctatcttgg ttcaggaaaa acgatacttc
     5521 taaatcatat tctgtacggt gatcacggaa agaaaattgc tgtcattgta aatgacatag
     5581 gggaagtaaa tgttgatggg gtattagtcg acaagaaagg ttttaaaaga actggagaaa
     5641 aacttgtttc gatgccgaat ggatgcattt gttgtacatt acgcgaagat ttgattgttg
     5701 aactagatca attagtgcaa ttttctgact tgaatcaaat tgttattgaa gcttcaggaa
     5761 tcagcaaacc aattccaatt attcaagcaa ttatattagc taaaaaccct ttagacattg
     5821 atttgaccca acgattagag attggtgcca ttattatagt agtggatgta aaacgttttt
     5881 gggataattt cgaaacgggt gaaaagattc aggaaagaaa agctgaaggt aatgtagttg
     5941 aagaagaaca ggatattcgt ggcttgttaa ttgatcaatt cgagtgttgt aacatattac
     6001 ttttaaataa tagtgactta gtgtcaacca agacgattta caaaattaac ggtctaattg
     6061 ctaagttaca gtccaatgcc aaaataatta ggacaattaa aggtgaagta gacttatcga
     6121 aaattctaaa tacaaatctt tttaatatag atgagacttc ctattcagtg ggctggttca
     6181 aagagttaga gcttggctat caaaatcata ttcctgaaac agaagaatat ggtatctcaa
     6241 gttttatcta tcgaaatcgg ttactccttg acgcacaaaa atttgcccat cttacggata
     6301 aaaattttcc tggcaatatt acaagagcaa aagggtttct ttggtttgcc caacatagtg
     6361 atttttcgac gatctttgaa acatcgggta gctataaaag tattgaatca ttaaattatt
     6421 gggtagctag tttacctaaa attgagtgtc aaatgattat acaaaaaaat cccgaattga
     6481 aggaagcctg gcatccgttg tttggtgaac gcattaataa actagttttt attggtatga
     6541 agatggatca acaatgtatt aaggaacaac ttgagggttg tttaactgat tctcttaatg
     6601 cagataattt ccgaaaaatt tcaccatttc catggaaaaa gtctaatatg tttagccaga
     6661 tatcgttaat gaaattttta agaaaagctg gtgtcaagat aggcgatgtc ataattattg
     6721 gcattttgat tattacctct tttattccct tatttgtatt ctctatagaa aaggagaatg
     6781 aaacaactga agatgctatc aaatatgcca tcgttcgaat tgatggcaag gaaatggatc
     6841 gcttcgattt ggataagatc aatcataaac tcgtgaatta tcatcctgcg aagggacaat
     6901 ataatattgt tgagattaaa gatggaagaa ttcgagttaa agaagataat agtcctgatc
     6961 aaatcgcggt tagaactgga tggatctcaa aacccggtca aacgagtatt tgtttacccc
     7021 ataagttagt tattagtatt gagaaaaaag aaagcacaga ttactacatt tactaatctg
     7081 gaaatagatg aggaggtttt taataagaaa aagatattat tattaataat agcaggggct
     7141 ttattaagtg tgttaagcgc ttgtggacaa gaaaaagaag cggtgacaac aggcacaagt
     7201 atctttaacg ggacctgcaa tggtttagtt aacagtcggt tagattactt attttggctc
     7261 ttcgtcaatg agtgttggtg aagaaattca atagaataat cgagatactc acacggctag
     7321 acagctatct tgtctagccg tgttgttgtt ctggctttag tcagttgggt agtattctta
     7381 gttttcttaa aatattttcc tcgatataaa aagattcgtt ctcggtagtt ttgaaagttt
     7441 ctatagccat aggcaattcg ttttagtact ttgatatggt tattcaaaca ttctataggg
     7501 ccgttggaat agggaacgcg caacgctcgt ttgatttctg tttggtattt cttgaaggtc
     7561 gtgaacactg gttggtagtg ctctggcaac tccttgtagt cttcttttag gagcgcgacg
     7621 aattcaggaa catcttgtct tctgataacg gaaagaaaat cctggtagac ttcgtagcct
     7681 cgctttaagg aatcatcata agataatagc cgatcgacta tctctgcttc tgtcagatga
     7741 tctcgaaatg acggacgcca gtagcgatgc tgacctttca attcccacgc attcttttga
     7801 agtagtttcc agtatttctt taagtgcttc gaccgacgat cccctttttt aaaggtcttc
     7861 attacttgaa ttcggtggtt ggtaaaagcc cgaccaatgt gttggctaat atgaaagcga
     7921 tcggcgacga ttcgggcatt cggaaaacac tctttcacca atgtgcgata gggtgtatag
     7981 aaatctgaaa ccactagacg cacttgttca cggactttta tagggtagcg caagaaatag
     8041 tcgcgtaaag gattgagttg ccgattttcc acaatatcaa tcagttgatg ggtcttgccg
     8101 tccatcatga caaagctcat ggctcccgag acatttttca ctgatttgaa ttcatcgaaa
     8161 cacaccactt ctggtaacag ctggctcaaa gaaatggttt taggccgaag gctgcgaagt
     8221 attcgaatga cagtggtcgg agaaatgtgc ttcatacgtg cgatcaaaga catagaaaga
     8281 ggttcgctta atagctcaag aatggcttgt ttgactctgc gagcaatgga gcagcgacga
     8341 tcactaactg aatcttctgc taaaaaagtc tttccacagt gtttacattt gaagcgctgt
     8401 ttgttaatcc gcagaatggt cttgtagtta ctgacatcat tcaataagat ggatactttt
     8461 ttccagccct atttaatgat cgtttgttca ttttgatagt ggcgatgaaa gcattcctcc
     8521 ggttgatagg tcaatgtgcc atcaaaaaca aaacatgttt cgtcattgat tcgctctttg
     8581 cgaaaggcat cttcatgaaa gataagattt aggtctagaa tatctagtaa ctctttggta
     8641 aactctgaat aggacatctt gaaacactcc tttgaatggt tttcgtcgac tttattctaa
     8701 aggattttaa ggtgtctgtt tgcgtttatt agaaaaaaga aaaagtattg gcaacagaag
     8761 gcgtcaccaa cactagatat tatagatccc ttattttctt cgcttcaaat tgtcaaggag
     8821 tcatcataaa ttttgtatgg attcttttgt ttgggtagta gtcttctaaa taatcttgga
     8881 ttaacacctt catctctatt ttacttttat atttgttgga gtcgattaat tctcatttga
     8941 ttgatcgatg aaacgcttca attactgcat tgtcaacagg agtcccagtt tggctcactg
     9001 aatgtgtgat gtggtggtcg ttcaacagct cttgataaat aaaagaccga tgctggctac
     9061 ctctatcgga atgaattacc gtaggcaatt ctccttaata aatttgtaat ggacggacga
     9121 caatctcttt tttcatgtgt gaatctacca tatagtaacg tagaatacga gttgctaagt
     9181 caatataggt ggacaaatag aggcgaccgt cattacatgg aatgtaagta atatccatca
     9241 cccaaacagc atcaatttgg ttctgttcaa attatcgatt caacattttt ttaccatttc
     9301 tttgattgtt ttttctctac catgagaaga tttgcgtcga tgaaatcctc ttgtgcataa
     9361 attcatttca cgcataagaa cagctacaac acgtttattg atttcgattc cttcatcgta
     9421 aagtttttga gtgatccctg gagatccgta tcgatctttg tgttcgtaga acactcgtct
     9481 tcctctttta gtcgtttatt ttcctgttca agaatgtaga aatctgcttt atcaggtaat
     9541 ctttttcctt gtccagcaaa agcatttttc ccgtatcgac gatattctga aacccatcgg
     9601 gaaattgttg gacgagagat attgtattct tcagcaattt tcttggtagt tacttttttc
     9661 tcaaggatat cctgtgaaat ctttagttta aatttacgat catatgtttt tctcaataga
     9721 gttcattcct tccggtaacg taactgatag tcaagaaaag tgtatcatag cccaacttag
     9781 tatcagggtt tgtcaactaa actgtggaag ttgatagata agagttttta acaaccaaaa
     9841 ttctcttgac tatttttgaa atcagacaaa ttttgattgg acacatagtt gaataaatct
     9901 accgtcgtta cggaaggtaa atcgcatgct tttcaattct agaggagaag tcctcgttga
     9961 agtaccatag cccagttctg gattcgacct cctgcccact tcatacgtaa ataaagtaat
    10021 tttaggagtg agactgtgac aaaagttatt tttaagctaa aaacgaatta aaaaacgttg
    10081 ataattaaaa tcattcgttt tagattctat gaatcattat agaacgctgt aaaatcgata
    10141 ctttataatt ataaagaaga tagtttcaaa tttattgttc gaaatttgaa actatctttt
    10201 tacttatgtc acagactccc ttagttgagt tattctttaa tttcgaattt cgagatagct
    10261 agatatattg caagcataca ttcttgataa caatcttgat catattttcc agttctccag
    10321 gattgcttat gaatcaaaga gctaaatctt ttgagaattg cctcaacagc ttcttcattt
    10381 ccagcctttg ctaaaatgaa atcttctttt aaagaattca taaatctacc ttcttcccat
    10441 ggacttataa tctatttctt tgggaaggag gagaacgagc aaagaagcat acaaaattag
    10501 ttattatgca gatattaaac cagcattttt tgaatttttt tgtaaagtcg atgttttaaa
    10561 tttgtcgcac cctgtcttgt aatccccaga acctttccaa tttctttatc agttttatca
    10621 aagataaatt tttcgataag aaaaatttgt tcaggttctt tcaacaaagg aaggattttt
    10681 gctaatttta tatcttcaac aaggagagtc acatttaaaa cattaatcgg ttgtttaaat
    10741 tttatagtat ctttagtaaa caaatatggt gggagttgat caagttgttc atgtttttga
    10801 atttcttctt gttttttata ataagtatta gcggtgttca aaatgacctt ttcaaagaat
    10861 cgaatcaact gggcatttac gcgttcgtcg ttatctgaca tattgcacac ctcctccatt
    10921 aagatttaaa gggaaaagag gcaaaaaaca cgaaaagaag ctaatgcaat tatgctgcgc
    10981 tgcgaataac ttctataagc tcacatgcat tgataggact gctgatgttt attttcaaaa
    11041 atgttttt
//
LOCUS       DADVXV010000090        10082 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.091, whole genome shotgun sequence.
ACCESSION   DADVXV010000090 DADVXV010000000
VERSION     DADVXV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.091"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(109..2229)
                     /locus_tag="KB969_002391"
     CDS             complement(109..2229)
                     /locus_tag="KB969_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBB6870320.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="KB969_002392"
     CDS             2459..3637
                     /locus_tag="KB969_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBB6870321.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="KB969_002393"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="KB969_002393"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBB6870322.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="KB969_002394"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="KB969_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBB6870323.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="KB969_002395"
     CDS             complement(4990..6243)
                     /locus_tag="KB969_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6870324.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="KB969_002396"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="KB969_002396"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBB6870325.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFISGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="KB969_002397"
     CDS             7821..9167
                     /locus_tag="KB969_002397"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBB6870326.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="KB969_002398"
     CDS             complement(9475..9861)
                     /locus_tag="KB969_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBB6870327.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(9910..>10082)
                     /locus_tag="KB969_002399"
     CDS             complement(9910..>10082)
                     /locus_tag="KB969_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6870328.1"
                     /translation="VETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQR
                     RFEGTLRYSLGY"
BASE COUNT         3215 a         1839 c         2053 g         2975 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt atttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttattata cccgtggtgc
     9901 tagttaattt taatatccta aagaatatct caaagttcct tcaaaacgtc gttgtgctcg
     9961 acttaataga acactgtaag ccagtaatat gctttcaaat ctactctcta gccctttaac
    10021 agaacgtgag ttgaaatttt gacaacctaa tttttctaag gaagaaaaaa cagtctcaac
    10081 tg
//
LOCUS       DADVXV010000091         9965 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.092, whole genome shotgun sequence.
ACCESSION   DADVXV010000091 DADVXV010000000
VERSION     DADVXV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.092"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            343..549
                     /locus_tag="KB969_002400"
     CDS             343..549
                     /locus_tag="KB969_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBB6870329.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(751..1752)
                     /locus_tag="KB969_002401"
     CDS             complement(751..1752)
                     /locus_tag="KB969_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBB6870330.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1757..3670)
                     /locus_tag="KB969_002402"
     CDS             complement(1757..3670)
                     /locus_tag="KB969_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBB6870331.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3838..4344)
                     /locus_tag="KB969_002403"
     CDS             complement(3838..4344)
                     /locus_tag="KB969_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBB6870332.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4504..4944
                     /locus_tag="KB969_002404"
     CDS             4504..4944
                     /locus_tag="KB969_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBB6870333.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(4970..6127)
                     /locus_tag="KB969_002405"
     CDS             complement(4970..6127)
                     /locus_tag="KB969_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870334.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6130..6486)
                     /locus_tag="KB969_002406"
     CDS             complement(6130..6486)
                     /locus_tag="KB969_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870335.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6784..7758)
                     /gene="sgrA"
                     /locus_tag="KB969_002407"
     CDS             complement(6784..7758)
                     /gene="sgrA"
                     /locus_tag="KB969_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBB6870336.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(7954..8793)
                     /locus_tag="KB969_002408"
     CDS             complement(7954..8793)
                     /locus_tag="KB969_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBB6870337.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            8978..9865
                     /locus_tag="KB969_002409"
     CDS             8978..9865
                     /locus_tag="KB969_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6870338.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
BASE COUNT         2997 a         1988 c         1503 g         3477 t
ORIGIN      
        1 ggcttttggc ctcattttag gttatcattt gtaattttat ttcacagttg atatgattgt
       61 tatgtaaaat aaaaaagttt aggatacatc gaatttttgg ggaaattctt ttgggggtat
      121 cctaaatctt ttctattata ttcccatatt ttctattatt ggtctagacg tatgatggta
      181 aactttgtac ctatctgatt gctgaatcat taattgctta tcattagcca tctttgtttc
      241 aagttcgcta gatgatcatt ttattcacat cctaacaaac ttgtcacatt tatagattct
      301 taatctattt atcatacaat tataaaaaag gaggtgctgc ttatgaaagc tatccatatt
      361 tctttgcttt ttttcgctag tgcattgatt ttatttgcta ttcatctttg ttcccagcct
      421 tatatcaata acaacggaat attagtggaa ccagcattct tttgcttacc actcggcttt
      481 ttgtcccttc ttgcctccgc aggcttcgga tttgttgctt tttttaaacg atcaaaacaa
      541 caaatctgac ttataaaatt tacgtaaaag agatcgtgac aataatcgtg tgatattccc
      601 aaatttcgaa taaaaggtgc cccttgccat ctctaactcc tcagtcacaa gttacaatat
      661 tcataaacca tgaaaagctt gtttattgaa attgctcctt gtgacttgga gctaagtgac
      721 agattacaac ctcttttgca tcataagact ttactccttg aaaaacatta ctaacttttg
      781 atatgtttct tgcgcttgtt tattgctgaa atcaaactga tattcatggt tcaaaacagc
      841 atttttctcc gcataatcta cttttgtgac tttcaccccc gctttctcaa atacagaagt
      901 tacttcttcc atttgtttcg taaacgtatt tgtatttcca tccgttaaga atgtgttttg
      961 cgtccaacga tccgcatgtc tgaccaaggc taaacttttg accttctctg attgttcaaa
     1021 gtccttatta tcaaagtaag cccatccaca tttttcataa agaaagctag agattttatc
     1081 acttacttga gtaagtgcag aaggatccaa cagaccagac aaagaaataa acttcgtaat
     1141 ctgcttgttc tccaaagtcg gatcaagatg atcagctttt ttaatttctt cattttgaag
     1201 tgctaacaaa tattctccac taatttgtgc acctgccgaa tttccaccaa tcgaaatatt
     1261 cgaccaatct gcttgatctt ttatctcttt tttagctgct tgaatggctt cgttcaattg
     1321 gataactggt gtaggatgtt ttgcttccgg tgatcgttca taatctatat ttacgatgat
     1381 ttgctgcgtg tctgaacata gatattccaa ataatcacga caatcatttt tatcccctcc
     1441 tacatatgcg cctccatgca tccagaaaag aatcggtaat tttttctttt ccactttcgg
     1501 tgtgtagata tccatattat tatttttgta ctttgaagga taggatattt ctttttttat
     1561 atcgatttgt tcgatttttt gctggaaatc atctggtcgg gcatatactt gttctttttc
     1621 acttgtgtca aattgttttc taacaagcaa gctaatcggc tttggtgtga tttgattaat
     1681 caaaaataca gtgactaaaa taactacgat gataactggt actgcaatca ctattcgctt
     1741 gaaccatttc attcatttac cctctctttc ttcgccaaat ccatgtgata atcgtgctaa
     1801 cagataaaaa tccacctgaa taaatgagaa gcgaatgttt cttttctcca gttttcggca
     1861 acattctttt ttttgcatct gtcttttttt gtactttcac tgtcatctga atcggttgcg
     1921 tatcatcact tgattgatcc tctcgaggtt cattctttcc cttattgtct gcattctctg
     1981 tcggatcttg cttttttggt ggagctactg ggattttttt gtaatagaaa ataatagttg
     2041 gtatcgtctc attaaaaatc ccttcagtcg gtccttcaac atttgctaat tcgtatcctt
     2101 cgaatgtctt ttgctctgtc atataatttt ctccataagc tccgtaaagc tggatttcgt
     2161 cctggtcttt gagtagactt ttattgtttt catccacata ctttacgttt atctgatcat
     2221 ggaacactac tttcaaaaag tccgttacat gtttcgtgta ggcagcatgg tcaacttcct
     2281 gtgcctttcc atgccctgct ccttctacta ataaaagatc tttataccct cctgataact
     2341 catataattt ttgcgcgtta gacacaggta ctacatcatc tgctgttcca tggataatca
     2401 atttaggcaa tgaatctgac attccaatcg taggtagagc agcttttgta tccaaatgca
     2461 tctcctgatc aaaatagtat tgtttcaaaa ggcccataaa taaatcttca tgctcttgat
     2521 ccccaatgat gtctaactga ttttttatgg catccggtag tgcgggggct actgtctggc
     2581 tgtacgtaaa acgtagttgt tcatcaattg atgcaaatcc gcaattttca ataattcctt
     2641 tgacattgac aggaatatct ttcgctaata cagacatcat cgtagctgct cccatcgaac
     2701 caccataaag taaaatcttt tgagatggcc gctctcgaac ttcttgattt atccagtaaa
     2761 ggacgtcatc tgactcatat tgtccatagg tcacataatc gcctccgcta ttaccagtcg
     2821 ctctggaatc aacaaataat aaattatacc cggccttata aaaatcattg tattcttctg
     2881 taacgatccc gttattccaa ttccctcgaa atccgccatg gatcatgact gttttatctg
     2941 aaccttgatc gacataatat gcatatacat ccatcatttt gccatcttgt ttgtttagta
     3001 cagtttgatg aagttgtttt gtatttggat agaagcctgt gttttctgta ggcgttgtcc
     3061 catcatctgt acctccaagc atcgacatca acacactgtt ttttgcaaaa gcgatatcgt
     3121 acaatagata agtagcaatc agatgtttga taatctcttt atctacacca taatcattaa
     3181 cagcaagctc agtgactaat aactctatta attttgactt gatgtcttct gttggtccat
     3241 taagtatttc tgtcatctgt ttaccgaagt aattcaaata ttctttacca ttgaaatttt
     3301 cacctttacc gatatcatca ttttctgtcc cattctcttt gtcacttact ttagcagaag
     3361 aggattcgtc gtttgacatt tttgtagctg ttgcttcttc tgtttgttgg ttatctgtgg
     3421 tagcggtcgt ttcttgatct gtgctagtaa cagatgtctc aaccgttgtt tcagtatttg
     3481 tttctgtttg tgaagtactc gatttcgttt catttccagc atcagtagtt tctgtggttt
     3541 ctacctcccg agattccgat tcggaagaaa tgctctctcc atatactgtc cattgcggga
     3601 cgcttgtact tacagcaaat aagatgacca acgctccctt taatacttgt tttgttctca
     3661 agctattcac tcctttttat gtttctagga gaattatatg taaacgcaaa cattttttat
     3721 acaaaaaata aatggtttat cccataaaaa tagaacagga ttattttctc attttacgta
     3781 ataaagcaga atggataaac cagtatccat tctgcttttt ttaaacgaag aaacaactta
     3841 ttgctccaaa aatgtcagaa atcgtttatc ccaaattttc tcgtaaaaag cgattgtttc
     3901 ctttgctttc ataaaaggat tatcataagt tgtcgttgct cctctacaca tcataagctg
     3961 gtatcctaat ccatgagcaa acttcacagt cgtatctata caatactctg cttgtgcccc
     4021 acataattcg atcgaatgac agtccaattc agttaataaa acactcaaat tagtcttata
     4081 aaatgaattc gcatgggttt ttctcacaaa ataactgtgc tcaggaatag ataattccga
     4141 caatagctcc catggttttg tttgtggcac taattgagca tcttcgtgtt gaacgaaaat
     4201 aactggtttc ccaatcgttt cgtatgtttt gattctttta ttcactaatg ctgtcactgt
     4261 ttctaattcg tgtatcggcg aagaatcaaa acatacccct ttttgtaaat cgatcactac
     4321 tattgcgtcg gctgtgtttg acatacttgt gccttctttc ttttttcttg atttaatagt
     4381 atttcttatc tagctagttc cattatacgt gacaacattt tcttatttta cacctctaaa
     4441 tggcactttt cgactatttc ttcatgttat tatttcataa atacttagct attggaggaa
     4501 tgtatgatga ttaaattgta tacaggttct ggctgctcgt cttcaagacg cgcaaaacgt
     4561 tggcttatcg tccatgatat accgtttatc gaacagaact taattcgtca accactaacc
     4621 aaaaatgaat ttatccactt actaaaattg acaaacaacg gcgtgaccga aatgctctct
     4681 actcattcta ttagttataa aaatcttgtt cacagaatag atgaactcag tttgagtgaa
     4741 ctatatattg agattcgtac atccccttct ttattgaaaa aaccgattat ctacgaccaa
     4801 tctgcaaaac ttttgactgg atttagcgaa gataaaatca ggatgttcct ttctaaaact
     4861 aaaagaaagc aagagctcaa cgaactcttg ctttctggtc atcttgtcga ttttaaagaa
     4921 aataatcttt ttgcaatgtc ttaattttgg cataaacaat ctgcttttct taattaacga
     4981 aatccaattt ttccaatatg gatctatttt tctcattcct gatttttatg atttcagctt
     5041 tcagacgcgc ccaatcattt tttgtaggtt gtccattcca gtaaaatatc tgtgtattcg
     5101 tttgatcata tgcctttttg tcgataggat aatcgctaat gacaatatca ggtaactgat
     5161 cagcggatgc actatatttt attgggcgtt cagtcataga taatatcctt ttctttgccc
     5221 ataattcctg tgttttacca tactttgatt gaatatagaa tatgacaggt tgttcgtgtt
     5281 ttataaaaat atccctgact aacatacagt attgaaaaat caaccgtctg ttcttttcat
     5341 aataagtatt aagctctgga attctgcgag ctaccccact aaaaaactgt tgcatgattg
     5401 gatacatcac tggaaatata tgctgaaaat ctctgtcttc tgctgatttt ccaaaagcat
     5461 ccaccttctt ttttgtccca aaaacccttg aatacaaatg gatcattgcc aaattgacat
     5521 atagataatt tttttctgaa gttgtaaaac aaatcttgaa gtttttttca aaattttcta
     5581 caatagacga ttcaatccag ccccaacttt cttgtacttt atctggagta tccaacaaat
     5641 cttcttccaa ataggtgttc attacaccaa acataaaata aaggtaagct tgctctgttg
     5701 gagtgatgtg attcatcgac cagaagtttg cttcaaaaaa aggctctagt atgtaatgcg
     5761 taaactcttc ttttgttatc aatggatgca caaatttgtt catctcttct gggacatacg
     5821 taatcgagtg gccttgtttc attcgttgca acgaaattct tagtaggctg atccatttct
     5881 ttctatctat actacgcgta tatggcgcat gtttcgcaaa tttttctaat agttgacgtt
     5941 tattttttat acttgataat atatcagaat gattttcgtc gaatgactgc caatacatca
     6001 agtgaaaaaa gtatcggata cggtattctt ctccttctat cggattacct tttttcaagc
     6061 tgcaagataa atgatagttt ttcaaaatag tattaagttc tcttaatttt ctttgaatcg
     6121 tacgcaaact tatataattt tttgactaag attttctaag gattgataag tacctttgta
     6181 aagtgaatcc agtaaaatat aaccaatcgt tccctctaaa agtatagaat aaactttact
     6241 cagtaaaaac tgagaagaaa actcgacttt tatcatcttg ttttctgaaa gaaaagataa
     6301 tttatattct ggataccttt cgcaaaacga ttctgcttgt tgaatcaccg aattcatctt
     6361 agccagggtg tagtttagat ctaaagcgat atccttcacc acatataatt tctcgtctct
     6421 ttcataacaa tagttcaaaa attgatatac ttgcctttca ttgatatcaa taaattcttc
     6481 aaacaaagta catactcctt tttatctatt atttagactt attccgacag ctacatgaat
     6541 aacgtacaaa tagattcgtt actgattttt cagagatact accatgcgca gtgtgcattg
     6601 tcaattattc ttgctcttat tttccatttg tgttcctgtt atttcctgtt tctcaaatat
     6661 gttagtaaac aaaaatagat ctggcaaagc tacaacttcg ccaggcaata cagcactctc
     6721 gaatgaaata ttcactcaaa aatctatcgt tttattcaat tttagatctg ttgcttttat
     6781 tctttatttc actcgatgga agagagaacg aaaatagctt gctcctacaa tcaaaatgag
     6841 taacacaccc atccatgtaa ttagcttgtt caaggttcta ctaccagttt ctggtaaatc
     6901 gctttttcta ttatctgttt ctttcgcttt ttcttgatga tcaattccac gagaaacaaa
     6961 atcaggctgt tttagcacac tttttaggtt gctccctgca tttctctttt gttccttagt
     7021 tggtatgata ggtaccaaat caagttcatt atttactttt cctgtgctgc tttcgctgct
     7081 cgtgcttcct gtgctactct cactactcat gcttcctgtg ctactttcac tactcgtact
     7141 ctccgtactg ctttcgctgc tcgtgcttcc tgtgctactt tcactactcg tactctccgt
     7201 actgctttcg ctgctcgtgt tttctgtgct aatttcactg ctcgtactct ctgtactgct
     7261 ttcaccgctc gtgttttctg tactgctttc actacttgtg ctatccgtac tgcttggcgg
     7321 tccaacaact gtccaactgc ttggtttcaa attctccgtg atcgtcatct gtccatcata
     7381 aaaaacaatc aaatcaactt tatctttact cttgatctca tcaatcgata gttctgcaga
     7441 aatcattatt gtatactcaa taccagcggt ccattgtacg tcttttaaat aaacttcccc
     7501 aataactttt tctgaacttc cattaccatc ccaaccatat gttagaacag catgtacatc
     7561 actagcattc acgcttttgt ttggtttgac tggaatagta atgacttgtt gtgtcatgtc
     7621 ataaacaatc cgatcagttt tcacagtaaa tgaaagattc tcatttgccc gttcatttgc
     7681 agaagtactg attccaatca ttgctgcaat tatactcagc ccaagaataa caaataatac
     7741 ggtcgctgtt ttcttcattt ctatcactct ccatataatt accttctatt tgataaagga
     7801 attatataaa atgaaaatga tgagaacacg acagtcagtt gtgaaaatct aacaaaagat
     7861 gtcgtgtatt cgcttgaatt tgtttacttt ttcgtttaat caatgacaga cttaaaaaag
     7921 caagaccgat atcagccttg ctttcttcat cttttattga taaacagcag tgtatttctt
     7981 catccgcttt gttttatatg catagagtaa caaaccaaca atcaagacta acaagaataa
     8041 tgtagttgat atagatgctt cagccccaaa gtttccccca gtaattattg tattttgcga
     8101 ttggatcaga gtggagaaaa aaccttgttc ttgcgttccg ctgactggta tacccaaaat
     8161 agctccttgt gtccaattcc aagtaatatg agcaccaata gccgtaaata aacttcctgt
     8221 actgtagata agtgcgctga aaaagcaacc tgctaaaaag atattgaaaa ctgccagaaa
     8281 tgtcatgtta ggattcaatc cgtgcaaaag agcaaataat gcagcagatc caatcattgc
     8341 tattaacgga ccaaatctaa gcatctgatg ctgaaaaaag ccacggaata aaagctcttc
     8401 tgatgccccc actgcaataa ataaaataaa actcgttatc agcggcacaa tgtttgcgtt
     8461 tcctgaatct aaccgatacg cccccgtcaa atataatgga ctagtaataa gcagaaacac
     8521 tccaattcca acaacgagac ctcccgctaa atacccccag tcttttcctc gaacagaaac
     8581 accataatct tctattcttt ttccttcgac cttactagca agaaataaag ctagtaaaaa
     8641 aacagctaaa tgtccgaccg taccggcaat tgctccaatc cattcactat ttccaataaa
     8701 catatccgca agtgcattat tgacaagaat tcctaaaaca aaaccaacaa agactattaa
     8761 aacagatcca atcaaccgaa taatcctgat catctttcat ccctccttta tattaagttt
     8821 aacaaccctt ttctttcttg tctcgtgaaa actatgtaaa tgttctccat catagagaga
     8881 atagattttt acgaactaag aatatctaca gcaaccttac gaaaatgaaa gactgtctcc
     8941 ctaattcttc tgttagactg tttttaataa ggaaaggatg ggaaattttt tgaaaaaaca
     9001 actactaatt atgtgccttt cagcatgtgc aattttacta ttctcaggtt gtagcaagtc
     9061 caatgaaacg attgcaacgt ttaaaggtgg aacacttaca gttcaggatt tttatgataa
     9121 cccaaaagtt aaatcaaata atcaaacact attaaaaaaa atgattgtct tcaaagcatt
     9181 tgatgatgta tacggaaaag agatttcttc aaaggaagta acaaaagaat ataatgaaca
     9241 aatcaaaaaa ctcggtccaa actacaagga acaattaaaa gcagttggcc aaacagaaga
     9301 gacatataag aaactcttta aacagatgct ggctttccaa tacggtttga aagccaatgt
     9361 aaaattaaca gataaagatc tagacactgc ttggaaagaa ttctatccag aagttagtac
     9421 acagatcatt ctattttcga ctaaagaaga agcagataaa gcaaaaaaag aagcaaatga
     9481 aggagaaaat ttctccaagc ttgttcaagc ttatggaaaa aataaaacat taaaggaaac
     9541 tgatggaaaa atgaattttg attcaaccaa tccagagatt cctactgaag taaaaaaagc
     9601 agcatttaaa ctaaaaaacg gggaagtttc tgatatcatt cctgtaacag atccaacgac
     9661 ttatcagcaa agctattatc tagtaaaaat ggtaaaaaaa caggataaag gttctaataa
     9721 agacaaatac aaatctgagc tagaaaaaat tgctaccgaa gcaaaaactc ttgatacgga
     9781 attcatggat aaaacaatcc gtaaagtgat gaaaaaagac aatgtaacta ttaaagatcc
     9841 ttatgtaaaa aatatattca aataaacaaa tttgacccaa ttggggatgt ggcaaaattt
     9901 gagaagtgat ttttggaaat tccttcttat ttttgaggca aaccactttt gccacaactt
     9961 catcg
//
LOCUS       DADVXV010000092         9653 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.093, whole genome shotgun sequence.
ACCESSION   DADVXV010000092 DADVXV010000000
VERSION     DADVXV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9653
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.093"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            120..1547
                     /locus_tag="KB969_002410"
     CDS             120..1547
                     /locus_tag="KB969_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870339.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1639..2004)
                     /locus_tag="KB969_002411"
     CDS             complement(1639..2004)
                     /locus_tag="KB969_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBB6870340.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2001..2366)
                     /locus_tag="KB969_002412"
     CDS             complement(2001..2366)
                     /locus_tag="KB969_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBB6870341.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2558..2806)
                     /locus_tag="KB969_002413"
     CDS             complement(2558..2806)
                     /locus_tag="KB969_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870342.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2805..2933
                     /locus_tag="KB969_002414"
     CDS             2805..2933
                     /locus_tag="KB969_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBB6870343.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2990..4684
                     /locus_tag="KB969_002415"
     CDS             2990..4684
                     /locus_tag="KB969_002415"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBB6870344.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4688..4807
                     /locus_tag="KB969_002416"
                     /pseudo
     CDS             4688..4807
                     /locus_tag="KB969_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4784..4957
                     /locus_tag="KB969_002417"
     CDS             4784..4957
                     /locus_tag="KB969_002417"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870345.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            5335..6468
                     /locus_tag="KB969_002418"
     CDS             5335..6468
                     /locus_tag="KB969_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBB6870346.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6499..6819
                     /locus_tag="KB969_002419"
     CDS             6499..6819
                     /locus_tag="KB969_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBB6870347.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6848..7312)
                     /locus_tag="KB969_002420"
     CDS             complement(6848..7312)
                     /locus_tag="KB969_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6870348.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7444..8697)
                     /locus_tag="KB969_002421"
     CDS             complement(7444..8697)
                     /locus_tag="KB969_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6870349.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8726..9043)
                     /locus_tag="KB969_002422"
     CDS             complement(8726..9043)
                     /locus_tag="KB969_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBB6870350.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9069..9389)
                     /locus_tag="KB969_002423"
     CDS             complement(9069..9389)
                     /locus_tag="KB969_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6870351.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
BASE COUNT         3126 a         1889 c         1719 g         2919 t
ORIGIN      
        1 aaaaaccttt tttaacggca tttatatgct ttttcagaaa ttaactgatg atttcaaaaa
       61 gaaaacatgt cataatattt cccatattgt gcaaaaaaat acaaggcgga ggctctacta
      121 tgattgaaga atatattgag aaaaatattt taagacagct gtttttatgt gggcaattct
      181 atgtaaataa agaagtcaat ctagaaaagc tctccaatct cctgcatgtt tgcaaaacca
      241 ctttactcaa tgatatcaat aacataaaaa aagaatttga agaacagatc gcttatacac
      301 atcgggaaaa ggaccgttac actttatatt tttcagaaca tatacctcga tgcaagatca
      361 tgcagcaatt gtctcaaaat tcgttgtttt taaaaacttg tctgctttat ttggaagaag
      421 atgaacctga ttatcttcaa ttaactgaat gtgaattcat ctctgtcagc aaagcttatt
      481 cattaaaaaa acaagtatta gcttatttta atgactgcgg gatcgaaatc gaccgctact
      541 cccctcgatt cactgaaatg gaaagacgtc tgctgcttct taatgtgtcg tatcgtttag
      601 gcggttttaa ttcttgggag ctacctgaat cgttttttga acgtgccgat cgtttcattg
      661 aatccgtaac ggaaaatagt ggcagatttt atgataaaga aaataaagaa atcttatcga
      721 ttggttttgc tatcagtttc ctacgccagc aagtgtgtgc tgtgacaata gattcaaaat
      781 ttatcgaaga aatcaaaaaa cgtcctattt acaattatgt cgaatcagca tgggaaaaca
      841 ctgatttcca aacctattat aaaaaagaag aattcgcctt tattttgaca ctattcaatc
      901 tttgtaatta tggtttccat tcttatcagt tgattgcgga agactttcaa cagctacacc
      961 aagtgtttat tgacaatact cccgaaataa aagaactagt tgctaccttt gaatctcact
     1021 tcaatcaaga attattcgga aaccaaccgt tcgaacgtgc gctgattcat ctgatgcgtt
     1081 cggcttggga taactatcaa ttattcatgc cagaaaaatt ttatctttta aatgaggaac
     1141 agacaaattt atataaagaa gtccagacaa ttttttccag ctggtccagc cagttacctt
     1201 atgatctacg gttgaatcct aattgcatgc gggcttttgt gatcgaattg agcggaattc
     1261 tccgtctgac aaaagaacat ctgactatct atatcgtcac aaattcggat gttcattatc
     1321 tgatttatcg ggaagccttg gaagctgtaa ctactttcga ttttcaagtt gcaccaacaa
     1381 tttattcaag tatatctgat ataaagaagt atgcgcagca gtcctcaaac cgggtattat
     1441 gtgaacgtac attatataca ccagatgcgg tccaatatga aaatattatt cctatttcga
     1501 tcaatacgat cgatcgagct atcatttcag ctgtgcaaaa caaataaggg gctgtgacaa
     1561 aaatcatgtc acagcctctt atttgttgaa gatgcccatt tctgtaacaa tctcttgata
     1621 cacgtcaggc tcacaacctc acttattttg gacatctacg ggtccgatct ctttatttaa
     1681 aaaataagaa atgatggttc ggataactac caacgccgct agttggaaaa tatcctgcaa
     1741 ggtaggtttg ataatcgatt cgatgatccc agctgaaaca agaatttcca aacttagaag
     1801 tatatagcct cccaacatct ttttaatagc attgttctcg ctgactcggt cgctttgcac
     1861 ttttgtatgg acaaataaat atttcaaaaa atccttgatt gatagacaaa caccccaaac
     1921 caataaacag atagcaaaga tatcaagtcc cagtacaagt ttttcgaaat atggaagaag
     1981 aaactgcatc aactctgtcg tcatcctacc tctcctcttc tttgtttttc tttgtcttct
     2041 atttcctgat tcaagaaata agaaatgact gttcgaatga taataataag tgcaagcttc
     2101 aaaatatctg tccaagtcgg cttgataact gactcgatga tatcagcaac gactagtact
     2161 tccaagctta acaaaatata acttgctagc agttttcttg tatctgcatt acgagtatta
     2221 cgttctgcat agtttttctt gacatgagac caatcaaaaa gtttgaatag aacaagaacg
     2281 atcccgacaa ttaagatacc gatagaacaa atatttaaaa tagcaatgat ccattctaga
     2341 aattcaatta aatttgagcg aaacatatac gctacctact ttcttttaat ttgttcctat
     2401 tcttttattg taaaagaaag ttaccttgtt cgtctattta aaagttgttc taatgataac
     2461 ggttcgctta aatttttctt tttcactctc ccatttttct ccctccatcc ataaatcgtg
     2521 gaagtatcca aaacaacgta gcaagttaaa ataaggctta gtccgtcatc agcttttcaa
     2581 agaagcactg tctcggtgct ttttttgtac ccaaatttct aaaaatagaa ccatacacct
     2641 cctcaaatct tttcttctta cctaccctat ttttatttac aggaaaatca gacacttctt
     2701 cttttttgtc aaaatttcct ttttcttctc gtcctatcat ttggcattct aataaaaacg
     2761 aactatcctt ggatatagaa agagaaaaca aggaggcgtt tttcatgagt aaaaaattaa
     2821 tcaaagtcgg catcggttta ggtttgcttg cccttggcgc tgcatatcta ggaaaaaaga
     2881 caggactatt cgaagatgac agtcatttat atgatgaatt cgaatcaatc tagcatccta
     2941 tttagttgaa tcactacgga catacttgga agacattgga ggaatcacaa tgagaaaaag
     3001 taaagcaata atgattggtg ccggtattgc caatatggca gcggctgttt atttgattca
     3061 agaaggcaaa tggaaagggg atcagatcac cttttattca ttggatgatc acggttcaaa
     3121 tgatggtgca ccgaccgaca ctgtagtgga tgaatattgg aataaaaacc atccattaga
     3181 aaaccaaaaa ggctatattg ctcgaggcgg tcgcatgctt aattaccgta cctatgtaga
     3241 tttgatggat ctgttaagtc gaataccttc tgttactgag ccagggatga ctgctgaaga
     3301 agatacgaga gattttgatg caaaacaccg aacctttgac aaagcacgtt tgatggaagg
     3361 tggcaaagga atcattgatg gcggaaaact gggattcaat aataaagacc gtattcttct
     3421 gactaaactg attgctatgc ctgattcaga agaagaaaaa ctagacaata tcactatcga
     3481 agaatatttc aaagatgatc cacacttttt tgaaacaaac ttctggttta tgtgggaaac
     3541 aacatttgct ttcagaacac gtagttctgc tcaagaattg cgtcgctata tgcatcaaat
     3601 gatttatgaa ttcactcaaa tcgaacatct agtgggcgtc aatcgaacac gttacaatca
     3661 atacgaaagt attatgcttc ctttgatcga gtacttgaaa gaacaaggat gcaaaatcat
     3721 tttgaaccgc cgtgtcactg actgggaatt caaagaaaca ccgatgcaag atgaaatcac
     3781 tgtgactggt ttgaaaatta ccaatacact gactcaagaa gaagaatacg ttgtggtcga
     3841 tgaagataca gcagttattt tcactaatgg gtccattaca gattcagcta ctttaggaga
     3901 ttacgaaaca ccagctgtag aaaatatgga ttatggtgca gcttctagtc tctggaaaaa
     3961 agccagtgaa cgtttctaca acttgggaaa tcctgacaaa ttctttgctg atcgagatgc
     4021 aagcgaatgg gtcagcttta ccctgacgac gaaaaaccat ttgttgttga atgaaatcac
     4081 ccgtatcacg actcaagaac caggaaatgc cttgaattca tttatttcaa ccacaccgat
     4141 cacgccgtta ggccaaaaag atgtcaatat gtctattgtc gtgcatcatc aaccgcattt
     4201 tacgtctcag aaaccaaatg aaacagttat ttggggttat ttcctttatc caagacgacg
     4261 tggcgaattt gtggataaac agtatattaa aatgaatgga aaagaaatgc tagaagaact
     4321 gattggacaa ctttcaaaag tagatcctgg accagtgaat attcgtgaaa aagaaacaga
     4381 aattttcgac agcgtaataa ataatatccc tgtctatatg ccttatgctt ccgcgttgtt
     4441 caataatcgt gccaaaagcg atcgaccaaa agtcattcct aaacattcga ccaatctggc
     4501 ctttacagga gaatttgtcg agcagcctta tcagatgatc tttactgaac aaagtgctgt
     4561 acgttctgga gaaatcgctg ctttccattt tgcgggtatt cctatgtccc gtcttgtcaa
     4621 aacaccgcgt tacgacaaag atattcctac tctagctcgt gccgcaaaaa aaatgtttga
     4681 ataatcaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacaa ccaggctaaa
     4741 acagcttctt atgtttttga tttggttgga cttattaccg cagatgcaag cttttgaaca
     4801 ccgtttacca agaggttatg aaaaagctgc cctgcatcaa gtaataagag cagccaagct
     4861 aaaacagctt cttatgtttt tgacttggtt agacttatta ccgcagatgc aagcttttga
     4921 acaccgttta ccaagaggtt atgaaaaagg cgtttagttt cgagtatgaa gaaaaatttt
     4981 gtgaaaatgg ttcctcacgt ttttgcataa atttgactta ataccgagaa actgatccct
     5041 tctgtcataa cctcttttta tttatgtctg tttctttttg aaaacaacta ttttttcaac
     5101 gtttactctc ttgccaatcc aacatcatct aacggataca actatttcaa tgattaccat
     5161 tacactaaaa aatcggaaac acacctctcc gaacacaaat acataagact atagaatgtt
     5221 tcatttaaga aaaaaagcgt ttcattatca aaaaggtaag atctccttta aaatgaaatt
     5281 atctgtagta ctaataatgc agacaatttt atgaatctga aaggagcatc tccaatgaaa
     5341 gcagtcactt ggcaaggaaa acagaaaatg gaaatcagaa acgtagatga tccaaaaata
     5401 ttagaaccaa cagatgcaat catccgtatc acagcaacag ccatttgcgg ctccgatctg
     5461 catctttacc atcatggtga agcagttttg gaaaaagggt atgttgtagg acacgaacca
     5521 atgggaatcg ttgaagaagt gggatctcaa gttcaaacat tgaaaaaagg gcaacgtgtg
     5581 gttatccctt ttaatattag ttgtggtcat tgtcatttct gcctgaatca catggaaagc
     5641 caatgtgatg aatcaaatcc agatcagtta tatggcgggc ttttcggatt tggcaagttg
     5701 aacggtaatc attggggtgg tcaagcggaa tatctaagag ttccttatgc agactctact
     5761 tcatttgttg taccagataa tgatcttcct gatgaaaaag ttttatttct atcagatatt
     5821 ttgcccacag cttattggag cgttgaaaac gcaggagtaa aaaaaggcga tacagttgtg
     5881 attctaggtt ctggtccagt cggtctattc gctcaaaaat tcgctgttat ggctggagca
     5941 gagcgcgtaa tcgcagtaga tccagtacag caccgtctag ataaagcggc taattacaat
     6001 ggggttgaaa cttatttctt agaagacacg gcacaagctg gaacagaatt gtatgaactg
     6061 gctaaaggtg gcgcagatgt cattatcgat tgtgtaggaa tggacggatt agagcctgtc
     6121 aaagaaaaag cgaaaaattt agtaagctta caaagcggca caatctctcc attacagatg
     6181 gcatcgcaag ctgtcaaaaa atttggaaca gtccaagtaa ctggtgttta tatgactcca
     6241 gcttcttctt acccgctgca agaatttttt atgcgggata tcgctgtcaa gcatggacag
     6301 gcaccaatta tccatctaat gccaaaaatt tacgcaatga ttgcagaagg actattcgat
     6361 cctacacaaa tcattactca ttcgctgcca ctatcagaag cagcacaagc atatgagatc
     6421 tttgacaaaa aagaagataa aaatataaaa gttgttttga aaccttgaat tcagtaaaaa
     6481 atacaggtga ttttctttat gcccaaaatc aaacgaaata cccatgagat cgaaatagga
     6541 aaagaagaag atatcgaaat acgaggacgt cgcttccgct tctatttcca aaatcgttac
     6601 acattgatct cactggctgt cgatttatta accgggattt tctatatttt tggaagcctt
     6661 gcttccttaa ctaaaatccc cgatcgatat ggcacctatt tttatttggc tggtgctatt
     6721 ttcttgacga ttcgtcctat tctcagaatc gtaaggaaca tttttattta cgacgaaaaa
     6781 aaagcaatga agagaacaag caaaaaaaaa gaggcatgag aatttttcaa atctcatgcc
     6841 tcttttttca ccctatcgta tcactttgat acagacgagc ggtcgtccca ctttcttcct
     6901 tgaccattgt caaaaatgtc cactcgtatc gttcataaaa cgtggtatga tctgtaatta
     6961 agtaaagttt ttcgtaccca agttgatgca tttcttttct gatttccgct aatatccgct
     7021 tggctatccc ctgcttacgc ttttccggtt caacaaacag ggcacaaaga tttggtgtca
     7081 gatcagggcg gttatggaag tcgttttcaa tgacgcccgc tcctccgacg atggtttctt
     7141 tttcatctaa gaccacatac cattgaggaa tactttcctt attagcgatt ccagtacgaa
     7201 tactttcctc atacacaaca gcaggaactc cccattttga tgaaaaccaa ttcgcgcttt
     7261 gttttactaa ttctgggtgt tctcttaatt tgatccagtt atatgtaacc aatgtttaaa
     7321 cctccgacta aaataaaacg tttacaaaaa ttatacaagt ctttatgaaa attagcaatg
     7381 acaacaatag tgatgtaaaa aaaaaaacgg aaaacaatca cttgttctcc gttttttgat
     7441 taatcaagca tctaaagctt cttttcttct ttcttggatc gtagctacct tgacgaacgg
     7501 tagatagatc aaaatagaaa gaaccaaatt gacagcggct agtacaccac ctgcaatact
     7561 ttttgttgcc aatacaccgc caataattgg tggagttacc catggaggca taacggtagc
     7621 tgctggcact aaacctgtag aagtcgcaaa gtaagcaaca ctaactaaga ccattggtgt
     7681 caaaataaat ggaatgaaca tgatcgggtt caacacgata ggtaacccaa acatcgttgg
     7741 ttcattaata ttgaagacac ctggcgcaat cgacaagttt gttacaacca tatatggttt
     7801 gtttttacgt cctactaaat aaatagctaa cagtaaacct aaagttgcac ctgttcctcc
     7861 taagttgaca aagctgtcaa agaaaggttt gttcacgata aacggtgcgc tatgtccagc
     7921 tgcgattgca ttaacgtttg cttcaatggc tggcgcattg attgtttgca tcaaaggatc
     7981 gaccatattc gctccgtgta aaccaaagaa ccataagaat ggtgtgataa atgcaagcag
     8041 taaggcagat ggataagagt ttgcaagtcc cataaatggt tcttggacca ctgtatagaa
     8101 agaacctacg atatcatcaa caccgaatgc agcaaaaatt gcagcaacta aagcaaacgc
     8161 agagatagtg atcattgctg gtagtaatga agcaaatgct tttgcaactg ccggtggcac
     8221 accatcaggc attttgatga tcaatttttc atttccgctt aaacgtacaa agatttctgt
     8281 tgaaataatc ccaacaataa tagcaataaa caaaccgttt gagctcatac ctaatgctcc
     8341 gcctaaagcg aagaaagagc ctaaagaaat cacacctgcg gaaacaccgt cttttcggta
     8401 gccgttagct aaatgataag caagcaagaa agcaatcaag acagaaagaa tggcaaatgt
     8461 accgttccaa gcagcagccc cgaatccttt ccatgattca ccaccaaaaa ttgagttcat
     8521 caattcttgg aacccgggaa tcggtaagtt attgatcatt actgctaatg ctcctaagat
     8581 cattaacggc atactcacca taaatgagtc ccgaatcgca actaaatgcc gttgtgcacc
     8641 aatttttgat gctacaggta taaaatgttt ctccataaat gcaacaaatt tatccataaa
     8701 tcttccctct tttctttact gtagattacg cgttcaatcg acgatacaga tcaatgatct
     8761 cttttgctaa atctgtaaaa gctatagatg tcatcagatg atcttgactg tggaccgtca
     8821 aaagcgtgac ttcaacgtga tttccttgtg cttcttgtgt cagcatctct gtttgagagt
     8881 gatgtgcttg gactaaagat tcctctgcat ctttgatttt ttcatctgct aaagtgaaat
     8941 cacctttttt cgcagcagca atcgcttcca ttgcatcgct ttttgcattt ccgccaaaca
     9001 tgatcagacc catgatggct tctagatttt tttgatcttc catttattgt atcctccgat
     9061 aatttttatt atttgtttat tagtttttct gcttggtcga gtactttttc accattcatc
     9121 atgccatagt cagccatatt gattacatct aaaggaatgc ctttaggtgc tagcttttca
     9181 gcaaattgat tttgcataaa gcgtacttgc ggtcctaaaa gtaaaacgtc tacattttta
     9241 gattctagtt gattatccgc atctgaagca gatacagcaa agatgtctgc ttccattcct
     9301 tttgcttctg ctgccttttg catttttgtg actaggagac ttgtactcat tccagctgaa
     9361 catacaagca tgattgtttt cttttccatt ttaaacacgt tcctttctat acttacactt
     9421 gtatataagc aagtagcgtg ccaactttaa aagcgcttta aaaagttgat atcatcacat
     9481 ttaaggtcta taccaagttg catacacact aaaaaagaaa gcgcacacta aacacacaaa
     9541 ttaattttta ttaccttttt tcttttaacg tgcacaaaaa aagttgtgac acaaaacttg
     9601 tcacaacttt tttcaaataa acggtattca aaagcttgca tctgcggtaa taa
//
LOCUS       DADVXV010000093         9647 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.094, whole genome shotgun sequence.
ACCESSION   DADVXV010000093 DADVXV010000000
VERSION     DADVXV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9647
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.094"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            33..656
                     /locus_tag="KB969_002424"
     CDS             33..656
                     /locus_tag="KB969_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870352.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /locus_tag="KB969_002425"
     CDS             1106..2155
                     /locus_tag="KB969_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6870353.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="KB969_002426"
     CDS             2152..3033
                     /locus_tag="KB969_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6870354.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="KB969_002427"
     CDS             3036..3806
                     /locus_tag="KB969_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6870355.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="KB969_002428"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="KB969_002428"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBB6870356.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="KB969_002429"
     CDS             5117..6280
                     /locus_tag="KB969_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6870357.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="KB969_002430"
     CDS             6397..6807
                     /locus_tag="KB969_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6870358.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="KB969_002431"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="KB969_002431"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBB6870359.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..>9647
                     /locus_tag="KB969_002432"
     CDS             9380..>9647
                     /locus_tag="KB969_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870360.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIFIYFLPVITQVF"
BASE COUNT         3349 a         1638 c         2076 g         2584 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc tttatttatt ttctaccagt tattacacaa gtatttc
//
LOCUS       DADVXV010000094         9622 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.095, whole genome shotgun sequence.
ACCESSION   DADVXV010000094 DADVXV010000000
VERSION     DADVXV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.095"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..406
                     /locus_tag="KB969_002433"
     CDS             <1..406
                     /locus_tag="KB969_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBB6870361.1"
                     /translation="KRPIRITNDLKLSTSMIHLIDVIGNYPETSITELADRLGVTKGA
                     VSQQIPTLEKMNLISISQKKGNKKTKLVSLTKYGRKVYESHNYLHEELYSSINEALES
                     FSPDQISTIKQILEKVSYTINEYQVSLTRKED"
     gene            499..1661
                     /locus_tag="KB969_002434"
     CDS             join(499..775,775..1661)
                     /locus_tag="KB969_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6870362.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            1941..2921
                     /locus_tag="KB969_002435"
     CDS             1941..2921
                     /locus_tag="KB969_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6870363.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3043..4461
                     /locus_tag="KB969_002436"
     CDS             3043..4461
                     /locus_tag="KB969_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBB6870364.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4532..6001
                     /locus_tag="KB969_002437"
     CDS             4532..6001
                     /locus_tag="KB969_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6870365.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6011..6478
                     /locus_tag="KB969_002438"
     CDS             6011..6478
                     /locus_tag="KB969_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6870366.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6514..7386
                     /locus_tag="KB969_002439"
     CDS             6514..7386
                     /locus_tag="KB969_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6870367.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7467..>9622
                     /locus_tag="KB969_002440"
     CDS             7467..>9622
                     /locus_tag="KB969_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBB6870368.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDS"
BASE COUNT         3344 a         1404 c         1935 g         2939 t
ORIGIN      
        1 aaaacgacca atcagaataa ctaatgatct aaaactcagt acgagtatga ttcatttgat
       61 tgatgtgatt ggaaattatc ctgaaactag tattacggaa ttagctgatc gattaggcgt
      121 taccaaagga gctgtatccc aacagattcc cactttagag aaaatgaatc ttataagcat
      181 ttctcaaaaa aaaggaaata agaaaactaa acttgtatcg ttaacaaaat atggtcgaaa
      241 ggtgtacgaa tcacataatt atttacatga agagctttat agctcaataa atgaagcgtt
      301 agaatcattc tcaccagacc aaatttcaac cattaaacag attctagaaa aagtatctta
      361 tacaatcaat gaatatcaag taagtctgac aagaaaggaa gattgacatg aaaaaaatga
      421 tttttgaatc ggctacacta gactagacag aaaaaataag gtgtgtaaaa taaatgaaaa
      481 cacactggag gaatttttat gtcaagacgt caacgtagaa cctattcaaa agaattcaaa
      541 caacaagtcg tcgatcttta tctcgcagga aagccccgag ctgaaatcat tcgagattat
      601 gagctgacta cctcggcctt tgataagtgg gtcaagcaag cgcaaactac tggctcgttt
      661 caggaaaaag ataacttgat ccctgaacaa gtagaactaa ttgcattacg aaagaaaaat
      721 aaacagcttg aaatggagaa tgacatttta aagcaagcgg cgctgatatt gggacgaaaa
      781 gacaagtaat tgataccaat aagcacaaat actcaatatc agcgatgtgt aaagtgttaa
      841 acatctcttg ccaaacctat tattatcaag ccaaaccagt tgaagatgaa tcagaactgg
      901 aagaactcgt tcaagaagaa tttattcgca atcgaaaagc ttatggtacc aggaagctga
      961 agcagtgctt ggccaatcta ggtcttcaag tgagtcaacg cagaatcggc cgtatgatga
     1021 aacagcgtgg cttgcgttca acatacacat tggctcattt caaattccat tcttctactt
     1081 gtaacgaagc caagaccgcc aatattctag acggaacctt cctacaggaa aagtcattag
     1141 aagcgattgt aaccgacctt acctatgttc gtgttgggaa gaaatggcag tatatctgcc
     1201 tgattcttga tttgtttaat cgagaaatca tcggctattc atgcggggag aagaaagatg
     1261 cgacgttagt caaggaagct tttgcaaaga ttccgtactc gttgaataat gtacaacttt
     1321 ttcacacgga tcgtggaaaa gaattcgata accagacgat tgacgaaatt ttatgggcct
     1381 ttaatatcac gcgttcctta agcaaaaaag gctgccccta tgataacgcc gttgcagaat
     1441 ccacctataa atctgtcaaa gtagaattcg ttcatcaata ccgctttgag acattggcta
     1501 atttgcgatt agagctattt gattacgtcc attggtggaa taccatccgg ctgcacggca
     1561 cgttaggcta tgagacaccg atcagttttc gacagcagag attggcgcag cgaatccttg
     1621 ataatgagct cggatgtgat accggtggcg aggcacctta attatttgaa tgagcttctg
     1681 ccttagagaa tcagattcga ggaggctcgt tgtcaagggc agtcggaaca ccagcagcaa
     1741 gcttacgcaa taccttataa tttttgtcaa aaaaagtgtt gccattccac atatatcttt
     1801 aaacagctat tgccagataa aaataaatga tattatatat ataaatactt atccgaaaag
     1861 gggaatgaga gagtcaaggt tcttggaatg tcgaatagtc gagtaggtag attttctatc
     1921 tacaaccttg ttgtttaaaa atgaaaaaaa ttggaattag agaagttgcg aaagaggcaa
     1981 atgtttctcc tacgactgtg tcgagggtat tgaatgatcg tggatatttg agtgaggaaa
     2041 caaaaagaaa agtttttgat gccatgaaaa aattagaata ctatcctaat gaactggcga
     2101 gagcactttt taaaaacgaa acatataccg taggtttgat ttttcctaca attactaatc
     2161 catttcacgc tgagttaatt caagatatcg agttcgagct ttccagcagg ggatataaag
     2221 tgttgctgtg caatagctta aacaatccaa caaaagaaaa agagtacttg acgatgttga
     2281 gaaagaatca ggttgatgga attatagtag gaacgcacaa taaagatatt gcggattatg
     2341 atattccagg gctacctatt gtagcgattg atagaagtct tggtgaaaat acagttacag
     2401 tatcttgtga taattacagg ggtggggaat tagctactca actacttgta aatcatggct
     2461 gtcagaatat actgtgtatt cggggagata gtaagataaa gctacccgcg aatagtagga
     2521 ctttagcata taaagatgtt ttgaataaat tcatgctgga accgttagtc ctagaagtac
     2581 catttgtaaa agaaatcaat gaaaaaaatg aaataattaa gacatatctg gaaactcatc
     2641 caaatattga cggggttttt gcaggagatg atttattggc ttctttggcg attaacaact
     2701 taggaagttc gggcaaaaga gttccaaaag aggttaaagt gattggattt gatggagctc
     2761 aacaaacatt gatttataat ccagaattat caactattca acagcctata gatcaaatat
     2821 ctaaagtagc agtaaaaaaa ttattgaata tgattaaggg cgaaaaggag acggatgaac
     2881 tttcacttcc agtaaagctc ataaaaaaaa atacagcata agttaaatcg gcgaaaaatt
     2941 ccttcgtcga tttaaaaata tttttatgaa acgggttgac atatgaaacg ggttgacata
     3001 tattagttgt gaagataaaa accttttcac tggaggaaga aaatggagaa attattaatt
     3061 aaaagcaata atcatcaact ttactaccaa cctaaggatg tttgggtcgg agatgttatg
     3121 ccttacggga aagaaggaaa attctttatt tatcatcaac gtgatactag aaatccagtt
     3181 ccttttggag aaccgtttgg ctgggcttta gcaactacga aagattttgt tcattttgaa
     3241 gactttgggg aatctctttt aagaggggat gacaatgaga gagaccagtt tatctacgct
     3301 ggttctgtat ttgaggcaaa tggaaaggtt cacgcatttt atacagggta taatcgtgaa
     3361 ttcttagcgc agggaaagac atctcaagtg ttgcttcatg ctgagagtga tgattttgtt
     3421 cattgggaaa aatcagaaac agcattggag ttagaaccac aagaagggta tgatattcga
     3481 aactggagag atccatttgt cgtttgggat gatgaaaaag aagaatattt gctaatttta
     3541 ggggcgcgaa agggtcagga taaacatcta caaaccggac gtttagtgga atttacatca
     3601 aaagatttaa ctaattggga attcaaaggt gatttttggg ctccgggatt gtataccatg
     3661 tttgaaatgc cagaactttt caagattggt gactggtggt atcttgtcta ttcagaatac
     3721 tcagatggaa ataaaatact ctatcgaatg agtcaaagtt tggaaggtcc ttggattaag
     3781 cctaaagatg aagcttttga tggacgggct tattatgcag gtagaacagc ttatgatgga
     3841 aaacgtcgag tcctatttgg atgggtacca acaaaagatc aagaaaatga taaaaacaat
     3901 tatttatggg gaggtacttt ggttcctcat gaagtctatc aaaaagagga tttttcactt
     3961 ggggtaaaac ccatagacga agtgtggaat gcattcataa atttacatga tattgccgat
     4021 gtagagatag aaacagcaga cacaagagaa gaagtaacgc ttgtcaaaaa tagtggaact
     4081 ttgtttaatt tagaaacaac aatttcattt gatgagaatc ttagtgactt ttcactgaga
     4141 ttatataaaa accttgagac agatgaatct tacgaatatc gcttcaattt agatgagggg
     4201 cgtcttacat ttgataaaaa cccttgttac ccttggtttc aatatatgga taaaggactt
     4261 attagaccta tatctttaaa gcctaaccaa tcttataaac taaaagtgat tgttgatgac
     4321 aatataatga cactttatat tgatggaatc gctcttaacg ctcgtgtaca tggttgtttt
     4381 ggtcaagcaa ttactattac agcaacaaat ggatcaatga ctgcaataaa taccaagttt
     4441 tcaaatgaaa taaagaaata ataaacgtca atcatgtggc aggtctgaaa atcaaacatg
     4501 acctgtcaca tttaaaaggg aggataaatg aatggactac aaaaaaattg ccgaagatgt
     4561 attggaaaac gttggaggaa aagagaatat ctcaagcgct acacactgca ttactcgttt
     4621 acgtttaatt cttaaagaca aaagcaaagc gaatatggaa atgcttgagg aaatagaagg
     4681 tgcaaaaggt gttcttttca atagtggaca gttacaagta attttcggaa caggtataat
     4741 tgaaaaggtt tacaaagagt tcgttgaatt gacaggagct aaggaagtat ccgtttctga
     4801 aatgaaagac gaaggagtca ataattcagg aaatagactt caacgagctt ttaaagtttt
     4861 ctcggatatc tttattccga tcattccagc ttttattggg gcagcaatgg ttttaggaat
     4921 tcgttcgttg attaccactc ctggaatgtt tggaatggat ggctcattcg ctgatcacaa
     4981 tgtattccta aatgatttat ccaaatttct gggtattatt gcaaccacat ttgattattt
     5041 accagtttta gttatgtatt ctgcaacaaa acgttttggc ggaaacccta ttttaggatt
     5101 acttgtagga tttgttatga ttcatccagg actagccaat cggaatgatt tcgtcatggg
     5161 aactataaag cctgattatt ggcatttatt tggattaagc attccagcag ttgcgtttca
     5221 agggggtgtt tttccagcaa ttttgacttc ttggttttta gcaaaagttg agaaaattac
     5281 aaataaatat tctcctcaag tacttgctta cattttagtc ccaactgtga caattgttct
     5341 tgccaacttt gcactatttt tagtgtttgg tccattgggg aattttatcg gtaatgtttt
     5401 aggtggaatc attgatttcc tatatatgaa gatgggtgcc tttggtgctt ttgtttttgc
     5461 aggcgcgtta caaccattag ttgtaacagg aacacaacat gctattcaag gtattgaggc
     5521 aaacttagtc gcaacaactg gattcaatta tatccaacct atttggtcag tttcaattat
     5581 tgcccaaggt ggcggttgta ttggtatgta tttactcttt aagaaaaaat ctaaagatag
     5641 agatattgcg atttcaagct ttattccaac actggtaggt attactgaac cggctatctt
     5701 tgctgttaat ttgaaatatt caatcgttcc ttttgtttgc tcgtttattg gtgctggttt
     5761 tggtggagca tttatgaaaa tttttgatgt aaaagccatt ggacaaggat tgactgtatt
     5821 gccaggtctg actattgcta atccagttct tccttatata tttggtaatc tcatagcatt
     5881 cattttacca atcattttta ttctcgctta tgataaatat aaagtgttta tccctgaagc
     5941 taaacaccgt aaatttgcag aaaaaactga ctcaaaaaaa ttgccagttc aagtaaagtg
     6001 agatgagagc atgttaaatt tttttagaaa aaatgaaata agcgttgtag cacctgcaac
     6061 cggtgttttt gaaaaactgg agaaattaag tgatccagtc ttttcaaaag gaatgatggg
     6121 acaaggattt gcaattgatg caaaaaacga aacgattgta tctccaatcg atggttttgt
     6181 ttcaagtatt tttcctacaa aacatgcctt aggaataaaa acaaaatcag gaattgagat
     6241 acttgttcat gtaggaatag atacagttga gctaaatggt gagggatttg atattaaagt
     6301 tcaagaagga caaaaagtta aggctgggga tattcttatg accattaatt ttgtagtttt
     6361 tgaaaagaat cacaagacta aagatgtcat tgttgttttt ccagactacc aagacgaaat
     6421 tttcattccg aaacttgaag aagtaaaaca aggacaagaa ttgtttgttc ttggctaatg
     6481 ataagtaatt aataatagaa tcgaggaaaa tgtatggttt ttggggctat tgaagctggt
     6541 ggaacaaaat ttgtttgtgc cattggagat aaagatttga acatatttga aaaagtcagc
     6601 tttcccacga ctacacccaa agaaacaatg aatttagttt tagatttttt taatcatcat
     6661 aaagatgatt tagaaggtat cggagtggga tcgttcggtc ctattgatat tcattgtgaa
     6721 tctaaaacgt atggcttcat taaatcaacg ccaaaacttg cttggcagga ttttgatttt
     6781 attggaagtt taaaaaagca acttaatatt ccaactgctt ggacgactga tgtaaatgcc
     6841 tcttgctatg gtgaatatgt ttctggaaat ggcagaggcc tttcaagtgt tgtttactat
     6901 accgtaggaa cgggcatagg aggtggcgct atccaaaacg gaaacttcat tgaaggtttt
     6961 agtcatccag aaatgggaca tatgcttgta aaacgacaca ataaagacaa cttttctggg
     7021 acatgtccat tccacggaga ctgtttagag ggcttagctg ctggtccggc aatcgaaaga
     7081 agatcaggga aaaagggaca agaagtgact gaaaatgacg ttacttggga aatagaagct
     7141 tattacattg ctcagtgtgc atataataca acattgatgt tatcacctga tgtcattata
     7201 tttggtggcg gagtaatgaa acaaaaacac ttaaaaaaga aagtacaaga taagtttatt
     7261 gagttgatca acggatatgt cgctattccc gatgttgaca attatattat gacaccaaaa
     7321 ttgttagata attctggtat tgtaggttgt ttagctttag caagagacgt taaagaaaaa
     7381 tcttaatttg gaaaaaagat cgtctcgact atttgtttgg ttgatgcgat ctttttttca
     7441 attagtaatt gaagggacgc ctaaaagtga aaaaaaaaat gaaagatgaa gtattagagt
     7501 atatcaaaaa taatttaaag tattacgatt tttctgctca agatattgca atgaaatttt
     7561 gtattaaaag aaatgtcgct tcccactatt tgaatcagtt attttcagat ggaaaattac
     7621 taaagaatga ttctgttaga ccagtaatgt tcaagtataa tcaacaaaag ccaaaagact
     7681 gcttttctaa gtttattgga gcagacatat ctttgaaatc cactatagat aaatgcaaag
     7741 ctactgtaat gtatccccct aatggcctcc cattaataat aaaaggaaac agtggcgttg
     7801 gaaaaagttt tttagcaagt ttgatctatc agtatgctct tgatagaaaa gtaattcata
     7861 atgacgcaaa atttgttgtt gtgaattgtg cagattatgc aaataatcca gagctattgt
     7921 cagcagtttt atttggatat aaaaaaggag cctttactgg ggctgaaaaa gatactgcag
     7981 ggatgctatc ttctgctaat ggaggatacc tttttttaga tgaggttcac aatctaagtg
     8041 cagaaaacca agagaaattg tttcttctta tggattctca aaagtatcgt aaacttggtg
     8101 aaagtgtgca atgggagtat gcaaatgttc gccttatctt agccacaaca gaagataaaa
     8161 atacctcttt gttagcaact tttagaagac gcatcccagc tgaaatcact ctgccagatt
     8221 acaataatag aagtacatct gaaaaaattc aattattatt tgaatttctt aaagatgaag
     8281 caattacgat tgattcaaaa atattttgtt cgattgaact ttttactgat cttttatcga
     8341 aaacatttga aggaaatgtt ggagaattga ggaatgaaat caagcttctt tgtgcagaag
     8401 gttatttagg aaataagaga aagtcttcaa tttatttagg ggacaaacta gacagcggtt
     8461 tttggataga tccagaaatt agtatagatt taaaaaaaat gtttcttaaa tcactttctg
     8521 aaattgattt gattgaactt tttcaaaatc acatttcaat tgaagaaagc atgagtcaat
     8581 taagagatag aatacttaaa gagtgtgcag gttcttctga gtataattat ttagaaagtg
     8641 acgaatttat agcattaaga aactatgttg ttaataaaat atcaccaatt attgattcga
     8701 caggtctatg tttattagat gaattcttgg cggatatcag tctatttata atgtttattg
     8761 atgtaattga agaaacatca agaaattttt tgctgtctaa gttcagaaaa tttcgtatga
     8821 aaaatgataa acaaaaatta ttggcaaatg agatttggag tagtttagaa gtcgaagaaa
     8881 gtaaacaaga acttttgttg aaatggatac tttttcttgt aaagaagttc tatgtgaaaa
     8941 taccagaaac ccattgtctg atagttatgc acggtaaaat aacagcttct gcgatcgcaa
     9001 gggaaacaaa taagttgctg aatacatatg tttatgaggc tttcgatatg ccaattgaag
     9061 gtgagactag tgacttaatt aacctaatca acaatttttg taaaagtata gatacgacga
     9121 atggactcat tctgctagtt gatatgggat cattggaaca aatgtatgaa aaaattgaat
     9181 ccaatgtaat aggtgatttg gtaattttaa acaatgtttc tacagcttta gcgattgaat
     9241 gtgggattca agtttgccaa aaaaagccaa ttagtcattt ttaccagatg gattttgatt
     9301 cgtttcaagt taaagttcag tattataaag gattatcaca aaagaaaaat gtaatagtat
     9361 cttgtctctc tggtgagggg atttctgaaa aagttaagga tattttaaaa cggtatctcg
     9421 ataatcaagt ggagattttg atttttgatt ttaacgcatt aaagaaaata gcaaaggaaa
     9481 aagatactat gatttttaag aatacaattt gtgttctttc aaccactgaa ttttacattc
     9541 aaggaatcga ttgtttaaat ttagaaaatc taattaatgg gaatcaaacc ttagaaaaat
     9601 taaataagta tatggactcg ga
//
LOCUS       DADVXV010000095         9322 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.096, whole genome shotgun sequence.
ACCESSION   DADVXV010000095 DADVXV010000000
VERSION     DADVXV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.096"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..107
                     /locus_tag="KB969_002441"
     CDS             <1..107
                     /locus_tag="KB969_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HBB6870369.1"
                     /translation="NESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(176..904)
                     /locus_tag="KB969_002442"
     CDS             complement(176..904)
                     /locus_tag="KB969_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6870370.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(917..2197)
                     /locus_tag="KB969_002443"
     CDS             complement(917..2197)
                     /locus_tag="KB969_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBB6870371.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(2338..2940)
                     /locus_tag="KB969_002444"
     CDS             complement(2338..2940)
                     /locus_tag="KB969_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBB6870372.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            3185..3391
                     /locus_tag="KB969_002445"
     CDS             3185..3391
                     /locus_tag="KB969_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870373.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            3703..4422
                     /locus_tag="KB969_002446"
     CDS             3703..4422
                     /locus_tag="KB969_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBB6870374.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(4503..5186)
                     /locus_tag="KB969_002447"
     CDS             complement(4503..5186)
                     /locus_tag="KB969_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBB6870375.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            5405..7591
                     /locus_tag="KB969_002448"
     CDS             5405..7591
                     /locus_tag="KB969_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBB6870376.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            7937..8347
                     /gene="spx"
                     /locus_tag="KB969_002449"
     CDS             7937..8347
                     /gene="spx"
                     /locus_tag="KB969_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6870377.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            8361..8717
                     /locus_tag="KB969_002450"
     CDS             8361..8717
                     /locus_tag="KB969_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBB6870378.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         3363 a         1526 c         1745 g         2688 t
ORIGIN      
        1 gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa ttggccaaca ttttatccag
       61 atacaatgga tggacgtgaa attgcacagg aaatgctttt gcactgatag gcaaaaaaga
      121 accgaagggt ttggatcggc tggtcattta gtcggtccaa actattcggt tctttttatg
      181 aaatcaattt ctttaatcca cggatagagg ctgggatggt ctcgccgttt gccaacgtga
      241 cttctctggt ttttttatta atcgaccgca cattttgtgt attgataaca taggatttat
      301 gacaacggat aaaattccga tgcattttct cgatttcttt gatcttctca tagaattgta
      361 attgggcatg agtcaaatgg acttccagtt tatgtggcgc tcctagcgaa gtagaaaaat
      421 attggatgtc tttgatcggt aaaaatttga tctcatcatt aaactctatt ttgaagatat
      481 ctttttggat ttgggacatt tgaaaatctt cgaaaatttt gctcaggata tgctcgacat
      541 tttcttttaa atcataaaga tcttctttga cgatataatc agtcggttcg atgttgcttt
      601 ttaagatttt catcgacatt tccgtatggg aagtcacata gattattttt cctaaaggat
      661 ctaattcacg gatcaattta ccgatcgcta caccatccat ttcactgtct tctagttcga
      721 tatctaaaaa gtaaatacca aaagaagaag ttctgatctt ggctgcattg agaagttctt
      781 ccggatcaga ggtagaaata tggacataac tgtctaagtt ttcaatcatg attctatttt
      841 tgatcaccgt tgataaaact tctaattgtt ttggatcgtc ttcacaaata taaatgggaa
      901 tcatatcatt actcctttat tttatttgta tataaatcgt ttgagaaaaa cgctggtttt
      961 caattgatgt ttcaaggaaa agataaggat tggtctttgt caattcatcc aagataaaca
     1021 agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa ccctttttgt ttcaactggt
     1081 ttaacggtaa tgtatttgtt gttgtattga tcacacgaat catcacggaa tgattcttct
     1141 tgagtatggt caattcgatt tttttcttct ttgcagcact agctccttca atcgcattgt
     1201 ccaagataat accaagcata cgtacaaggt ttaccgtatg tttcgtatcc agttcgattg
     1261 gctcaggaaa atgaagctgg acgatcaacc ctttttcctg tgccatcatg agttttaatg
     1321 acagtaaact acggatctca ggaactttca tattatccaa catacttaga ttggccggaa
     1381 aaaggttcat catctggcgt gtaggtaata tcgtttgatc ataataagac cgtaatcctt
     1441 ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag cagattttgg taatcatgtt
     1501 tgaattctct caagtcttga tagttttttt ctagatcttt gatataatcc tgttgcatcc
     1561 tgacttgttg ctctaataac tgatcagcta atttcttatt agagattttc caataataaa
     1621 ccaagatgat caggccaaca cacagatata gaatgaaaaa actcgtattc aaagctaaga
     1681 catcaggtgt ttcaccagaa aaacgggtat aaaaaataat gatatagtat gtaaataata
     1741 tcaatgtccc gatcgtaccg atcatacggc ggtccacagt gtgaaaccaa gtctctaacg
     1801 atttttttaa acaaaaagct aataaagcag ataaaaaagc ggataagaca atgtgaaaat
     1861 actgcaatga atctcctggt tcaataaccg aagatttcaa aacaaaaaaa tcgccgatgc
     1921 ttgttaagtg atctcctaaa agcgacgtca ataacccaaa aggaagcgcg taaaccaatt
     1981 gttgacgcga agtcgaaaag aagaaaaaag taagcatcag cattcctata gcaattagag
     2041 cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa aatacaagaa atcagaatga
     2101 ctcccgcaaa cagatatttg tatcggatgt gatggtcaat caataagata caaattgtgt
     2161 aaatcaaata ttgcaacgct atggaccata aaaacataaa gtacagctcc cattgatttt
     2221 taccaaatta tagcacaatt ggcgtattat ttttttaatt tttcagggat tttgaattca
     2281 gaactcatac caaagcagca gccagataca aaaaagtcag ataagttagt taattgttta
     2341 atgattgttt ttttcatgaa agattcctcc aaaattcatc aagtagtttg taataggaag
     2401 caacgtagct atttctaaaa caatcccaag tagcaaatag gtagaaaagt aagaagctga
     2461 gaaaaataac gtaatgagag aaaaaattag aaacatgctg atcgccttct ttaataatgg
     2521 gggacgtttc tcgggttcaa tgggattgat tgctgtacct cttgatccat agcgaagcag
     2581 taacaaaaag cagctgatta acaaaaagac catcattggg aaggagatag tcaattgcag
     2641 atgtttcatc accaagggaa cgccccataa ataaagtagt gtccacagca gacaaacgaa
     2701 ttcagagtcg gaatgcaatc cataagcata tctgcggatg cagatataag aaagaaaggt
     2761 gattcctgtt tccgcccatg agcctgtcac cagagaaaag actagaacga ccgctagttt
     2821 tccaagatta ttcaataaaa cttctaagac aaattttact tggacataca ccatatcttc
     2881 ttccgatttg tctccgctga ataaggcttc taataatttg ttcacaactt tatctttcat
     2941 ctcatacgta cctccaccac aaattttatg ctaaaaaaaa taaaaaacgt cttttgtttc
     3001 ataaaaagtg gttttgacat caaaaccgtc atgatctcct aaaaaaatct tcgttttcca
     3061 agaaccttac caaaaaaagt gacagttttg atacgaaaag tactttttat gacaagtttg
     3121 tgctttttcg agtgatttat gttaaaaaat tactgacctt ataaaaggtg atggagggat
     3181 tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca tatgcattta aatctgattt
     3241 atttgaatca ccaataaaag gaaaaataga aaaaatctat gaaaatagtg tgatgatacg
     3301 tgtcatgaaa tgcgcagtag aagacaatga taccgctcat aatctgcact ggcagttagt
     3361 tgtacgcaaa tcaagtacaa tagaagaata aaaacagata aaatgttgag agcataaaga
     3421 ggttgtgagt ctcccgttta gctctgagtt acaaggaata atgttaaaaa acagcttttc
     3481 atgttttatg aatattgcct tgtgaccgag gtgttggcag gagaatactg tttatttgaa
     3541 aaaagggctg cgacaagact tttgtcacag cctttatttt catgaatagg agttactttt
     3601 ggctactttt agagaagtag cttttaagga gcagataaag tcaaggcttt tatttctata
     3661 aatgaagtag taaaatgaag aacagatttt attacaggaa ggatgccgat aattgtgatc
     3721 attgttgcag gaacgatcgg tgcagggaaa agcacactaa ctgaaatgct tgcccaagat
     3781 ttagaaacaa aaccttttta tgagaacgtg gaagataatg aagtattgcc gctattttat
     3841 tctaatccag aaaagtatac ttttttatta cagattttct ttttgaacaa acgctttttg
     3901 gcaatcaaag atgctttcag ccatgatgac aacgtactag accgctccat ctacgaagat
     3961 agtatgctgt ttcatttgaa tgcagattta gggcgtgttt ctgaagtaga agtaaagcag
     4021 tatgaaggtc ttttagaaac gatgctgaag gagttagaag aaatttcgcc acaaaagaaa
     4081 ccagatctac tggtttatat tcgtgtatcc tttgaaacta tgttagcgag aatcaaaaaa
     4141 agaggccggg aatatgaaca gctagaacaa gatcctgaac tctattccta ctataaagaa
     4201 ctcaatcgac gatacgaaga gtggtatgaa cagtttgata tatgtcccaa aatagtgatc
     4261 gatggggaca aatatgattt cgtagccgat ccggcatgtg gagaacaaat cgtacaagaa
     4321 atcaagatgc gggcaaagaa aatgacagaa gaggcagatg cccagtcgat ccgctacact
     4381 acaaataacc cgaaagcaaa gggaatcttt acaactaaat aatataaaaa ctaagcaaat
     4441 tgctcactcg cagatatttc tctgtgagca gcatcttgct tagttttttt gattcattga
     4501 gatcaaatag tgaaccgatt cgtatgataa aattgccata aatgaaatgt ctgagtgagg
     4561 gccatgatca aaaataaaat ggaaacgatc aaaatcgaat gggcgccaaa cagatgatga
     4621 cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa cgacacttag atagtggaaa
     4681 aatcgatcaa aatctgcttt ttctttagaa atacaataat catataagtt cgttgctacc
     4741 ccttttaaat ttccagttgt aaataaatta gtgtaggcac gcccgttgat tttatcaaaa
     4801 gctacccact ggatcgatgc agtaaaagca atcaaaatcg ttactaatgc gggatgctca
     4861 tggacgggtg tcaaactaac aaagaaaaaa atcactgctt cataatatag aacaaacaag
     4921 cgccagaaat gtttttcttt ttttctaaaa taatcaatta gatactttgt tagaagaatc
     4981 cctaagaaaa agaaaagggt agacaatact tttttaccaa cacttagcca ttctccgtca
     5041 aatgcttgga tgatcgatag aatgatattg ccagtttgag cagaggcaaa agcaccatat
     5101 tggatataag tataactgtc catggctcct ccgataaatg tcagcaaaag tcctattgta
     5161 cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct tttatgaata tttttgtctt
     5221 ccttatctta gcataaacga ttgaaaaaaa aggaaaaatt ttcagaaaac taaaatcata
     5281 tcgcttccca ttttcatttt tagaaaggtc tgttagtata aagaaaaaat agacaacgaa
     5341 actttaaata accaacttga aataaacaaa ttcaaagaag aaagatggga aggaaatcaa
     5401 tcagttgaat gaaaaagaaa ttctccgatt acaaaaagaa ttgaaacgct gggagaacaa
     5461 gtataaaaag cttcaacaag tctttcggct acaagaagaa atcattgcta cctatgaagc
     5521 ggcttatggc gaagcacccg gacttattga ggaagaagta caagtaaaag aaagtgaagg
     5581 aaacagctct ttctttaaaa tgatggagaa acgttcctat aatcgcttca atcaagaaca
     5641 aaaagcagct atcacatatg atatgaagaa acatcttcga atcatagcag gagctgggag
     5701 cggcaaaacg caaacaatct gtgcaaaagc tgtttatctg atgacgcaaa aacaagtaga
     5761 cgaagaacgc atactaatga tcacttttac aaggaacgct gcaaatgaac taaaaaaacg
     5821 agtagataat ttcagccaga gaaaaaccgc tgtccatatc ggaacattcc atagtatctt
     5881 ttttaggata tacaatgaaa tttgtcgaaa atttcctgaa gtagcaatgc aaggaataca
     5941 aggagacttt tcaaaggata ctgcacaaaa agtgaatgct gttttgcaac agctgatacg
     6001 taaatataat ctttatatat ttgatcaata tggagaaaaa acgattgctt ctcggttaga
     6061 ctattggcag aatatgaacc tttcagtaga agaaatggtt cagttagtta aagaaaaata
     6121 tgattccatt gataagaatg cacgacagcc gatatcagaa cgactgtatg gattgctcac
     6181 ggaactccaa gaacaaaaaa gaagccagca attgctagag ttcaatgatg tactccaaaa
     6241 tctgaaaagc gctttggaga atgaggagat ccagcattat atcggccaaa aatatgatta
     6301 tctattcatt gatgaatttc aagatactaa tccacttcaa tgggaaatcg tgaaacggat
     6361 gacaaaggaa aacaggatca agttgattgt tgttggagat gatgatcaga gtatctatgg
     6421 attcagagga tcagagccag catacatcaa gaactttgaa aaagaatatc ctaccaaaac
     6481 tcttttctta ttaactaatt atcgttctcg ggcagctatt gtccaaggag caaatagatt
     6541 gatcagctat aataaaaatg atcggatacc aaaggcgatg attccagcac aaaaagaagc
     6601 aggtgttatg gaagcctatt tgttttctga tactaaagca gaaagtcagt ggctaatcaa
     6661 acaaattcag acatttattc aaaaaaatgg gaaatataag gaatcaatca tattataccg
     6721 atcagcttca caaacgcagc agcttgtcca atctctgctg aaaacgaata ttccttttgt
     6781 actggaagca gatagtccat atgaaggtat ctttggtatc aagtctttcc aacatttcta
     6841 tcaaaaaatt gttcattggc aaacagcact gaatctgcaa aagaaaaatc aggcctacca
     6901 gcaattgctc cggcagctga tggcagactg ctacctgaaa aaaagtgaat gcgatcaata
     6961 cttttctcct aaatatcaaa atatagccgt tgcagattat attttgtcga taagccccaa
     7021 tttaaaatcg aaatctgcag aaatccgaga gtttgaggaa gcgttgcgta aaacagacca
     7081 gcatcaagaa atctattcgc ttgttcaaag ctatcttcat ctgccacgta tagctaagga
     7141 aatcgaccag agtgatcaag aatggatacg agaagaagta aagcagcatg ctactttcag
     7201 aagactccaa gccttatcgc aagaaaccca agcgacagct aaagaattaa aaacccgctt
     7261 gattgcttac agacaaggaa aacttgatgc actatgtatc cagagcattc acaaaagtaa
     7321 aggtcttagt taccgaaatg tctttttgat tggttgtaac gaaggaagtt tgccttataa
     7381 cggagcgaca gaaaagaaag taatcgactt taatgaaata aaagcagaac cagtaacgac
     7441 gatagaagaa gaacgaagac tattttatgt tgcgatgact agagcaagaa atcgtctgta
     7501 tctatgtgta cctcaaatga aaaattcaag aaaattgaaa gtatcgagat ttatcaaaga
     7561 aaccgggagt cgtgtgaaaa aaggaaagtg atagaagaga gggtgtgaca gaagtggtca
     7621 gtttcaagaa agaagaagga atgtacgaaa attgcttctc aaatttttgt gaaatttcag
     7681 cttattttcg aagaagctat ttctggaaca cagtttattc ggaaaaggga ggtgtgacaa
     7741 gaattttgtc acacctccct tatttatttt gaaaatgaga atactattat caaaatagag
     7801 aatatataga aaaattctca ttattcaaac gtaaataatc agttattttg atttttttta
     7861 tattttatta gctaataatt ggtattttaa aagaaattac tgtagaattg gattataatt
     7921 aaaaaggagt gagaaaatga taaaagtata tacttcgcct agctgtactt cctgtagaaa
     7981 agcaagagca tggttgcaag cgaatcaact tgaatttgaa gagaagaata tttttgccga
     8041 accgttaaca gaaagtgaga tcaaaaagat cttggcagcg actgaaggag gagttcaaga
     8101 tattatttcc actcggtcga aaatttacga aaagctgggc atagatttta acgaattaac
     8161 tttaaagcaa atgatcgtct tattcaaaga atatccttca ttattgagac gacctatttt
     8221 gattgatgaa aaaagaatac taatcggatt taatgaagat gagatccggt catttgtccc
     8281 tcgtgaaatt cgatgtgttg ccagaaatct gatctattta caaaacaata acatcttaaa
     8341 ttcataggga gggagccttc gtggaagtga aagtctatgg atcagcgcac tgtgtaacaa
     8401 gtctgaaggc gaaacaatgg ttagaacacc atcaattgcc ttatcaattt gttgacttag
     8461 aagaacgcga tttaagtaca gaagaagcag aagaattatg cagttttgaa gaagtgcaag
     8521 cagaacagct atttgcgact tggtctgagg cttttcacaa cattgcgatt gacctttcct
     8581 gtgtaggaaa aaaacaactg atttttttat gcacacaaca taccaatctc ctcagacgtc
     8641 ctttgattat tatcgatgaa gttctattta ttggatacaa tgagcagttg atggaacagc
     8701 ttatcttaaa taaatagact ttaactgttt taatcaagtc actgagcatt tcatacagtt
     8761 gtaacagtcg aacacttagc atcaagcgtg ttatgtgttc tttttttgac tttatttttc
     8821 tactatagag acatgctcaa tttatgtggt caaaattcaa atctaggtgg ggatatagag
     8881 ttaaaaatat attgacatgt gtaaatttac atgatatatt catttctgtt gttttaagta
     8941 gcaaagcaat aaaatagtat tttaaaaaac atataaaata gttgttgaca tgttagaaat
     9001 gacatgataa gataactgag ttgttaaaaa agaaccactt gtgaagcttg attctatcga
     9061 aaaaaacttc aaaaaagttc ttgacaaata acaaatgata agttatgata aatgagttgc
     9121 tgtaagattt cgaaaaacga aatcaaaaaa acttttaaaa aagagttgac aattacttgt
     9181 ctctctgata tgatataaaa gttgctacgg cagccaaaaa cgaatcgggg aacactcctg
     9241 atgaagtaga cctttgaaaa ctgaacaaag taagacaaac caaatgtgta gggcgtcttg
     9301 attcaattca agacaacaaa ca
//
LOCUS       DADVXV010000096         8948 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.098, whole genome shotgun sequence.
ACCESSION   DADVXV010000096 DADVXV010000000
VERSION     DADVXV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.098"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..1350
                     /locus_tag="KB969_002451"
     CDS             <1..1350
                     /locus_tag="KB969_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6870379.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2827
                     /locus_tag="KB969_002452"
     CDS             1484..2827
                     /locus_tag="KB969_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6870380.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2939..4390
                     /locus_tag="KB969_002453"
     CDS             2939..4390
                     /locus_tag="KB969_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBB6870381.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4739..5371
                     /locus_tag="KB969_002454"
     CDS             4739..5371
                     /locus_tag="KB969_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBB6870382.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            5959..7398
                     /locus_tag="KB969_002455"
     CDS             5959..7398
                     /locus_tag="KB969_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6870383.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            7693..7911
                     /locus_tag="KB969_002456"
                     /pseudo
     CDS             7693..7911
                     /locus_tag="KB969_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8160..8375
                     /locus_tag="KB969_002457"
     CDS             8160..8375
                     /locus_tag="KB969_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870384.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(8592..8848)
                     /locus_tag="KB969_002458"
                     /pseudo
     CDS             complement(8592..8848)
                     /locus_tag="KB969_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3145 a         1359 c         1788 g         2656 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttaaaggca gtaacaggat taaacattga
     2821 aacataatcg ttactaaatg aaatcaagaa atatactgta ttactcaatt cattgaaaat
     2881 atttatcata atttttaata gaaaacacta ttaaagagaa aaaagagagg taaatcaaat
     2941 gaaaaaatct ttaaaacttg catcagcagt tatattaatg tcccaactcc ttatagcaac
     3001 acctttccat gtgttggcaa gcgaaaattc aacatacaaa attgcaaaag aaagaaccga
     3061 gacgactgaa atgagtaatt ccgatgtaac agcagagagt agtgaacttt tgacaacttc
     3121 atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcat caagtgaaag
     3181 tagtacgact tcaaatgccg agtcttcaac aacttcatca agtgaaagta gtacgacttc
     3241 aaatgccgag tcttcaacaa cttcgtcaag tgaaagtagt acgatttcaa gtaccgaatc
     3301 ttcaacaact tcaagtagta caagtgaaat aacttcttcg aaagtgacaa aaccaaacca
     3361 tatagaatct tcaaaaaagg aagcgccaaa aacggaagga caaacaaaaa ctttttcgac
     3421 accacagcaa atagaatcaa cagaatcttt ccaatcacaa ccaatactat ctggtaatga
     3481 agaaattcat tttgacaaaa atgaatctgt agaaaatttt attatgaaaa ttggtgagtc
     3541 tgcgagaaaa attggtcaga aatatgattt atatgcttct gttatgattg cacaagcgat
     3601 cttagaatct gccagtggtc aaagccagtt agctcaggca ccgaattaca atttatttgg
     3661 gataaaagga acttataatg gaaactttgt cattatggta acaaacgaag atttgggtaa
     3721 tggaacgctt tatacgaccc aatcaaaatt tagagtgtat gaaaactatg aggaaagctt
     3781 tgaagattat gccaaattat taactaaggg aattagtgga aataaagatt tttatgcagg
     3841 agcattaaaa gctaatagta aaacatatcg agaagcaact aaattcctta caggacggta
     3901 tgcaacagat acacaatact atttgaagct aaatgaatta attaaaacct acgatttaac
     3961 caactatgat aaagaagtta aaggtccaca aatgagtaag actggatacc aagtgcctat
     4021 tcataattat tcaataacca gtttgtttgg aaatcgtgga aatgaatttc accgaggact
     4081 tgatatggca gctacacagg gtgagccgat tcatgcagtt aaagctggta aggttgttaa
     4141 agcagagttt cactactctt ggggaaatta cgtggtgata caacacgaag atggatcaac
     4201 cgcgttatat gctcaccagc aacaatacct agtaaaaact ggagataatg ttttgcaagg
     4261 acaaataatt ggctatgtag gaagtactgg gaatagtact ggcccacacc ttcatttgga
     4321 aatttgcaaa gatagtagtc tttctcagag catgttagtt gatccgaaaa ccttattatt
     4381 cggagactaa aaaaggtaat caatctgaca aagtaacaag aaaatggttg gattcttaga
     4441 cctttgatca ggatattgag actggaattg atatctcgat tacgatgggt ttgacaaata
     4501 aaacaagtcc attatcgaat atcgagtgta ttattgccgt ctttatgctc atattttgag
     4561 caggtttcac tagatgaaaa caatttatct atcttgagga tttcgtgtac gtatcgttca
     4621 gtcttgtatt gtaaattagt cataaaatca gactaagaaa aattggaaat atttttttct
     4681 gatttattaa aagttaattg aaattatatg gtacttcttt cttgggaggg taggtgcagt
     4741 gaaggaaaga tatggtcacc ttactgttgt tgaggagatt actcataatg gatataaaaa
     4801 atatcgttgc ctatgtgact gtgggaatga aacgattgta tatcgatcaa acttactatc
     4861 aggtagaacc aaaagttgtg gatgtggaaa ttataaaaat aggcataaat ataaaaattt
     4921 gacaaataaa acttttggta agttagttgc aatcaagcca actaaactgc gaagtgaagg
     4981 aactgttgtt tgggaatgtc aatgtctgtg tgggagaaaa aagttagtat cggcaaagcg
     5041 acttctaaaa ggtgatgtaa aaagctgtgg atgtttgaaa tcaaaaaagc atcacattga
     5101 aaataaaaaa ttcggattac ttactgcaaa gtatcctttg gacaataact gttcatggaa
     5161 aacaaaatgg gtttgtcatt gtgagtgtgg cagtatgtgt gagataagtt atagtaactt
     5221 attttttgga catactcaaa gttgtggatg tttaaaaagg caagaaacaa ggacatgtgt
     5281 tgaagggaca gtaatagagt gtctaacgtc aaaattaccg aaaaataata caagtggtgt
     5341 taagggagtt tatcgttcta aagagaaata gattgcgtat ataactttaa aaaaaaagag
     5401 gtactattta ggatcgtatg attctattaa gagtgcagct caagctagaa aagatgctga
     5461 aaataaattg tttcaacctt tgattgacaa atatcgaggt aatcattaat tattgtggat
     5521 aataattaac agtgatatat aaacatctat aatatattat tcatactatt gatatttagt
     5581 ataatcctat ggaattgaat atcatagcaa tgtatttgaa aagcaaattg gaaaacaaat
     5641 aggtgcaaca ccataaatat gaaaaaattg ggaaaaagta gaatggaaat ttgcttacgt
     5701 ctcacgagat agctcacact attaatctga agaacaatga agtcgacttt tagaaattgc
     5761 tagaagaaag taaagcgaat tatcactagt tactatagag taagttcaaa taaagcatct
     5821 ccaacttaca tggttacatg aggatatcaa atcgaaatta ctcaagcttc ctatggctag
     5881 agtcgcgaga agttgttggg cagtagacat aggttatatt gttcttagct acacgatcat
     5941 tagaaaggaa atcctattat gtatagttat caagaagatg caaaagtcca aaaaaatcgc
     6001 tggtggattt tgattgctat atctatgttt accttcatgt ccacattgga tggcagtatt
     6061 gtcaatattg cactacctac catctcagat gatatgggca taccaatgaa tcaagcggaa
     6121 tgggtagtgt ccgtttatct gatgattgtc tgttcttgtt tgttgctgtt tggtaaaatt
     6181 ggcgatagcc gtgggaaaat caaagtattt cggattggta cgctgatctt tgtcttggga
     6241 tcgctgttgt gtgggttcaa tcattcgcta ggtattttat tgttcgcacg ggtggtacaa
     6301 gccattggtg ctagtatgac tatggctaca aatgccggaa tcatcacgga agtctttccc
     6361 atacatgaac gtggtcgggc attgggagca ataggtgcgt ttgtttcatt aggctcgatt
     6421 gctggaccag gtcttggcgg cttgattttg tcccaatttt cttgggcgta cattttttgg
     6481 atcaatgtac cggtgggaat cgtaacgatg ttgattgctg aaaaattctt accaaaagat
     6541 atcaccatga gcggccatac aatcgatgga gggggctttg ctgccattgc ggctacgatt
     6601 atcagctttt ttggagcaat ctttttgggg caagaaagtg gctttttcca tccagtcccc
     6661 cttgtactgt tcgtaatttc agtgattgcc tttgtcagct ttttaaaagt tgaaaagaaa
     6721 gcagcctctc cattgatttc tttcggtatt tttaagaaca agatttttac catgagcttg
     6781 attacagcct tgttgatttt ttcttccaac ttctttgtca atgtagtgat tcctttttat
     6841 ctgcaaaatg ctcgcgggtt gagtcctagc tatgctgggc tgttgatgat ggtctttcct
     6901 ttgatgatgg tcgtcggggc gcctttaagc ggctacctga ccgaccgggt tggcccggag
     6961 attttggtat tagtaggctt gggcttattg tcggtaaccc aggtcatgta tatgtttttg
     7021 tcagtggact ctcctttgtg gctatacatt gtcgctactg ccatcatggg tgccggcaat
     7081 gccttgttcc agtcccccaa taatacgatg gttatgagct cggtcactat cgaaaacttg
     7141 ggactggcag gctcgatgaa ttcctttgcc cgaaatttgg ggatggtcag cgggatttcg
     7201 ctttctacga cggtcttata tcaagcgatg tctgctaaga tgggccagca agtaactaac
     7261 tatatcgcaa atcggccgga tgtcttttta tatggaatga agattacctt tttaggcagc
     7321 tttgttttgt gttttgttgc ctttttcctg actatctggc gtatcaaaaa acaaggaggt
     7381 attcagaaaa atgtctgaaa aaaccactgt tgaagaattt ttggaggcct gcgtatgggt
     7441 gagtgggatt tccatggatg atggaagatg aagtgaactt ctaaaagccg aaaaactcaa
     7501 gtattatctt caaaatacta gtgctcaatg agatgcttga tttgatcaca agaagactgc
     7561 gaaagccgct ggcaaccgca agctaggtat cccaccgatg gactacgttt tagaggctac
     7621 tggttatgaa tacggagcca acgctctcat ctgcataaga atacatcacc cagattatgt
     7681 aaagattttc gatacttctg tcaaaaaatc attaagatag ataaatgatt tccgtctagt
     7741 caaattggtt cagaatgtag acacacagat ggtaagaagt cactcacaat tcgagaatgg
     7801 acttgtccta tttgccgtat acatcataat cgaaacgtca acgatagtat caatattttg
     7861 accaagggct atgaatacaa gcattgcctt agaaaacatc aagaacctta ggaacaacgg
     7921 ggatagcttg gttaataaga gataccgctg tttaggcttg caagtatact cttttatcaa
     7981 gaattccgtg gctttagtca tgagaggctt aatactatga aaattttctt tagcattttt
     8041 gatttaggtt ccttttctaa ttataataag atgaccacta cagtaaccta ctgaaatata
     8101 taaacagcca ctgtagtacc attttcaaag tagtctatga gaggagaatc ttcattctta
     8161 tgaacgctgg aattgcggat atgaatttaa taaaaaaaac ccttaatgat tttacttcca
     8221 attcaatatc aaaaggtact ggtatcaatt taagcacaat aaaaaagctg aaaagtggtg
     8281 aaagatcagt ggaaaagctg aatcttttag atgctataaa aataacggaa tttgctatga
     8341 aaaatggaaa agctgagatt gaaatatgga gataattatc gtctagtgaa ttacttgcca
     8401 cttagctgaa tttaacgatc cttggtgctt gaagggggag attcttggga atagagcata
     8461 cttgcaagcc tatgtcttta ctaacaacga tatctcttat taaccaagct atccccgtag
     8521 ttctaaggct tttactttta tctaagcaat aatcgtattc aaaggaaatt tttgaccctt
     8581 agaaagtctc attttatcag acgtgagctt aggcattgct gaattttgtt aattcggttt
     8641 taggttgtgc tttgagcata atatgaaagt attctttatc acgatttcat tcatctaagg
     8701 taatgtgatg tgattctgaa attctttcaa aggcagtttt tgcataagct gacattacat
     8761 catcaatgac atgtttacaa tgtttcacta ctaaaataag ggggtaacca agaagaaaaa
     8821 ctgaatgatt atttgtatct aattccatgg tatatcaacc atttcctata tagactgatt
     8881 atgacatgga ttaaaataaa aaggcactat gtcttaattg tcggttttcg agttaccgaa
     8941 tggcattc
//
LOCUS       DADVXV010000097         8850 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.099, whole genome shotgun sequence.
ACCESSION   DADVXV010000097 DADVXV010000000
VERSION     DADVXV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.099"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            63..1277
                     /locus_tag="KB969_002459"
                     /pseudo
     CDS             63..1277
                     /locus_tag="KB969_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1456..1785)
                     /locus_tag="KB969_002460"
     CDS             complement(1456..1785)
                     /locus_tag="KB969_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBB6870385.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(1775..2047)
                     /locus_tag="KB969_002461"
     CDS             complement(1775..2047)
                     /locus_tag="KB969_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBB6870386.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(2498..3301)
                     /locus_tag="KB969_002462"
     CDS             complement(2498..3301)
                     /locus_tag="KB969_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBB6870387.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(3279..4403)
                     /locus_tag="KB969_002463"
     CDS             complement(3279..4403)
                     /locus_tag="KB969_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870388.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(4419..5234)
                     /locus_tag="KB969_002464"
     CDS             complement(4419..5234)
                     /locus_tag="KB969_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6870389.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5224..6096)
                     /locus_tag="KB969_002465"
     CDS             complement(5224..6096)
                     /locus_tag="KB969_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBB6870390.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6181..7470)
                     /locus_tag="KB969_002466"
     CDS             complement(6181..7470)
                     /locus_tag="KB969_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6870391.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(7698..8342)
                     /locus_tag="KB969_002467"
                     /pseudo
     CDS             complement(7698..8342)
                     /locus_tag="KB969_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2742 a         1883 c         1409 g         2816 t
ORIGIN      
        1 caaaatcaat tctaccttag atgttcttat atcactctat cagtcctatt tgacaaagag
       61 ccaagaaaaa gacgttggtc gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa
      121 gttgtggttc tactgtggta gatggaaacg ggaaagcaat tatagtgaaa aatgggaaga
      181 aggaaacgat tgtccgtttt gaacaataca atcatatgcc tttggttacg cgcctaaaaa
      241 agcaacgcta tacctgtaaa aactgtcgta cccattggac ggctcaaagt tattttgtcc
      301 gactcagcca ttcaatcgca gatcatgttc gatataaaat tgcttcttta ctgactgaaa
      361 aagtatcttt gtcttttatt gcgaaaagtt gtcaggtatc tttgactacc gttactcgta
      421 cattgaaaga gtttaaaagc tatttaccaa agccttctaa gaagattctc cccagagtat
      481 tgatggttga tgaatttcgt tcgcacgctt ccatagaaga taaaatgagc tttatttgcg
      541 cagatggtga aacaggaaac ttaattgctg tcttgcctac gcgtaaatta cctcgattaa
      601 caagctattt cttaggctgc accaatccag aagaagtaga attcttagtc acagacatga
      661 acgccgctta cttccagctt accaaacgtg ttctgccaaa tgcgaaagta gtgattgatc
      721 ggtttcatat tgtcaaacac atgaatcagg cactcaatga gttgcgtatc cgtgaaatga
      781 atgagcttcg taaagcagga cagaaaagtc aggcagaaaa actgaaaaag aactggcgct
      841 ttctgctaaa aaatcgtgca agcatcaacc attatgagta caaaacatgg aaaagtttcc
      901 gagcaccaaa atacccattt ctcactgaag caatgatgat tgatcgattg cttgagtttt
      961 ctgcgcctct aaaggaggcg tatccctttt ttcatgaatt agtcgaagcc tttcgagaca
     1021 aagaccctga cttatttttc tccttattgg cagaacttcc cgaaacgtta gatgacggct
     1081 ttcgggagaa gcttcaaaac cttctgacct atgaagaagg tatcaccagc gcaatgatct
     1141 atccttattc caatggaaaa attgaagcga agaataccca cataaagaca atgaaacgag
     1201 tatcctacgg atttaaatca ttcgagaaca tgagaattag aatctttttg atcaatcaat
     1261 taatcaatgt aagataacaa aaaatctgaa ccagaatgtg gttcattctg acccggattt
     1321 gattttgcac aactcatcag tccttattga caaagagcca aaaatctgag ccagaatgag
     1381 gttcattctg acccagattt gattttgtac aacccatcag tccttattga caaagagccc
     1441 ttctttttag tattattata attcttccat gcgttcttcc agtcgctgta aatcgcttgg
     1501 acttaattcc ccaatttttt tccatttgac ctttttgttg tttttgggta attcgtttag
     1561 agttcctacg tcaatccaag attctttttt tagtcctgcc tgtttccaat cccttatttc
     1621 aacgtatttc agctttattt tatcggattt agtatgatat tttgaagtaa ttgacagaaa
     1681 cgaaattgtg tccagtccat tttttagaat atagacaggc cggcgtttac cgccctctgc
     1741 agctgtgaaa gcaacgtaga cggttgctat atcattagta ttcatcttca ttgaaccatt
     1801 cttcaatttt ttcgtcagtg tctagttttt ggacaggcaa tttttccgct aatctttgaa
     1861 tattatggat tcgtttactt ttttccgaca attcaataga aaatgggatt tttccttgct
     1921 caacaatttg cttataaaaa acggtgacgg ctgttttggg gctcatgcct agttcatcaa
     1981 taatgctttc tgcttcattt ttcaattttt cgtccataga aatttgtaac ttagccattt
     2041 tctccacctc tttctgacaa acacattata tcacggaaag agttcaaatg gaattaatac
     2101 aactactttt gaactccttg aaatgcagtg tatttatcta aatataagga aaggatatag
     2161 tgctaaatgg ccttgataga tagaaaagtt tcaaaatccg ccacagcgat aattgaagcg
     2221 aacactcaac gacacacaga acaggaaaag actcctaaaa gaaccaaatt aactaggacg
     2281 tgtctgaaaa ctccacaaag atgtggtatg ctctggtaaa aaacgaatgg cacaaccacg
     2341 aagaccgata tggttcttgg aaaactttct ccaccctttt tgtaattgga gggatagtgg
     2401 tttattgata gcgattttcc aagttcttca agtggaacca gacattgagc accacggcta
     2461 aaaagtgaat gaagtcttta tttttaatca ataattttta atgattacca gtaattggtt
     2521 ttttcatgcg ccctatttct atttgatgtg gagttaaata atgctgataa gtaaaaattt
     2581 ttccgtcaat taaactgcca ctagtgaatc ctgttctatt ggtaaaaaga gaatagtctg
     2641 ggtattcatc tacaccaaat gataaagatt cagccataaa ctgtttttta ccagcaaatt
     2701 cagcactgct accttgatgg atatgtccta caaaaatacc taaaatatca ctttcggcaa
     2761 tcaattcagc aaaaccttcc ggaacttcag ttacaataga tggatcttcc cacgacaatg
     2821 gatgatgaac caataaaatc gttccctttt cagcaggtgt acccaaccac tcttgtaatt
     2881 gaatcatctg tcctatcgat atttttcctt cgtgctgggt atcttgagca gaatccaagg
     2941 aaataattcg taacccattt tgattcgtac aatggatata ctctcccgtt tcattgcttt
     3001 caacactcat tccttcaaag aaaacactgc gacgatcatg attcccacga caaaaatagt
     3061 aaggtgtggt tgggaaatat tgatccaaca ttttccgtaa gacttgataa tcagaaatcc
     3121 ccccttcatg tactaaatca cctgttaata gaataaaatc gtacactgtt aacgagagtt
     3181 cttgtaacaa tttttccaat gccaactgtg gatttttaat tgttggaaat agttcagcag
     3241 taaacaagtt agtttgatag ttttctctaa aatggatatc agagagatgc aaaaagcgca
     3301 tggctattcc ctctttcttc aataaaataa tcaggatatc ctaaattttc ttgcgtctga
     3361 taatcaaaaa aatgcattct ttcaggttct atgcggagat tgactgcatc accaatctgc
     3421 caagtaggtt tttcattaag gacaatcatt tctataccat cgactttaac ggtgtacgca
     3481 taactttgac ctaatagctc acgatacttc acttgaccgt gtaaatcgct tgtttctttt
     3541 gaaaaggtta cgtgttctgg tcttatgcct aaatacaatg agccactaac ctgaagaagt
     3601 tgtttttgcc aagctggatt caatgttaaa aattgactgg ctacctttaa tgttccttga
     3661 tcataagtaa ctggcataat attcatgcct ggcgaaccaa taaaatttgc agtaaaagta
     3721 tttttaggtt tcgtataaac atttttcggc gtatcaatca tctgaattct accttcattc
     3781 aataaaacaa tccggtcagc taacgtcatc gcttcaattt gatcatgagt gacgtagaca
     3841 aaagtttgtt tataacgttg atgaattttt accaattctt ttcgtgcatc caatcgtaaa
     3901 cgcacatcca aatttgataa cggttcatct aataaaaaat aattactccg tttaaccacc
     3961 gcacgagcca atgctacacg ctgccgttgc cctcctgaca aatctttagg aagtcgatct
     4021 tggtatggcg ttaaacctaa catcttcaaa gcttcttcca aacggtgctg aatgtcagct
     4081 gtcttaattt tattcgccct taatgcaaaa ataatattct cctttacagt catgtgagga
     4141 tataaagcat aattttgaaa aaccattgcg atctctcgtt ctccacaagg tagcttattt
     4201 gctagttgtg tacctaaaaa aagctctcca ctcgtaattt tttccaaacc agcaatcatt
     4261 ctcagcaaag tagattttcc tgaaccagat ggtcccagta acacaattcg ttctccagcg
     4321 gccacagcta aatcaatttc ttttaaaatg gtatgttctc catatttttt tccgatattt
     4381 cttaattcaa gcgtttctcc catgatttgt cctccaattt atttaatacc tgcagaaaca
     4441 aaagtcccga taatatattt ttgaaaaatt gcatacaaga ctaacggtac aaacattgta
     4501 attaaactaa tcgccattgc tacggtaaaa tttgtcccac cttcagaact aatataggtc
     4561 tgcatcgcca acggcaaagt ataattatct actgtccgta aaattaatac cggccaaaca
     4621 tactcattcc aagaggtaat aaaaaaccaa ataccggtag aagtaatcgc atgtctagta
     4681 agaggaaaaa caattttact catgacggtt gtttgtttga tgttatccaa tgccgccaca
     4741 tctagaaggc tcactggaat ttcccgcatt gtttgcgtca ataaaaaaat gcccatcgca
     4801 tcagcaaatt gtggtattat cacaccccaa gtagtatcaa ttaaattaag ttttgcaatc
     4861 aacaaataat taggaatcat cgcaacagta aaaggaatga acatcgtacc aatgatgata
     4921 aagtaccaga ttttcttccc tttgattcgg caataagtaa aactatatgc cgcaaaaaaa
     4981 gctacgccta acttaacaac cgttataatt gtagcaataa aaaaagtatt tctcgtaatt
     5041 ttgataattg gaagattttc gaacaaatag caaaaatttt ccaaggtaaa cggctgtggt
     5101 atcaaactag taatcgtctg ataggcatct ttcaatggct taaaagaatt ggccataata
     5161 aacaataatg gatagataat aatgattatg atgaacataa ataagagatg tggcaaccag
     5221 cgtttaattt tcatagtaaa cccccttttc cacaaattta aatattaccc ctaagaaaac
     5281 agcaaatatt aataaagtta aaactgaaat tgctgaagat tctccgactt tatacatttc
     5341 aaaagccttt tgataagcat aatagatcac gtttgcacta ccattattcg gtccaccacg
     5401 agtgatgatc ttaatcggag taaacacata ctgcagacct tgaacaatgg tcatcaccaa
     5461 taaatatagt cctgtcgaac tactcatagg caacacaatt gtaaaaaaaa tgcgccagat
     5521 gggtacacga tccaacttag ctgcttcgat catctcttga tcaattccca caattgctgc
     5581 aaaaatgaca atgaaattat aaccaaaaac tttccaagca gtaatacctg caatcacagc
     5641 aattacccaa ccttgtaaat tcatccacat aggcagtctt aaaccaaaat ttcccaacaa
     5701 gacagcaatt ggtcccgata ccggatttaa tatccatgta aaaaccatcc ccgccactac
     5761 caaagaaatc acagctggaa taaaaaataa tggtttatac aaattctgcc ctttttctat
     5821 aactattcct aataaaaagg atgtaatata tgggaacaca cagctcagca agacaaatag
     5881 aacggtatag gacaaagtat tcttcaacac tttatgaaag actggatcag tcagcacctt
     5941 tacatagttg gcaaagccaa caaattcttt agtgggggcc accatattcc agtcaaaaaa
     6001 actcaaatag atcgtataaa tcaatggata aaaaacaaac acgcccaaca aaataattgc
     6061 tggcgccaga tacaaataac ctacatagcg cttcatttcc gacagcctcc tcatccttat
     6121 gtcaaaagca gacgaccttg tttttccttt cttacaggcg ctgtcgtctg cttgctttgc
     6181 ttatttgagt aactcattaa tttccttttg agtagctttc atcgtttcat tgacggaatt
     6241 acctgataaa attttatccc gcatatccaa caatttttgt tcagcttcta atccagcatc
     6301 tccaggaaat gaactccaac tgaccatctt atccatctga tcaattgctg gtatcatcat
     6361 ctgattttca gctaagaaag cttttaatcc attttgggcg tctgcaacat ctttacgtgg
     6421 tggtaaataa ccagtacctt ctgtccattt agctaaagat tcaacactat aaagatattt
     6481 taagaaatcc caagttgctt cctttttctt atccgtttgt gatgtaacag ctaacattgc
     6541 gccaccagca ggtagtttaa cttttttccc ttcccaactt ggtgactcaa ctgctttagc
     6601 agtaaaagta ctattttttt gaatgttgtc cctttgagca atagtggtat agaccatcgc
     6661 gacgttacca tcaataaagc tttgcacacc ttgttcccac gtagtgtgta atgccgtctg
     6721 gtcttttacc atcctttgat ataattcata agcagcgata ccatctttag aagcaaaggt
     6781 agctttgcca tcttttatta cacttgcccc attactttct aaaattgctt gttgtgccca
     6841 attatcagca ggttcttgaa tatacacgcc atactttcca gttttttctt ttattatctt
     6901 agaaaaagtt tgaacttctt cccaagtttt tggaccattt tcatccaagc ccgctgcttt
     6961 taatatatct tgatttaaat ataaaaccgg attactaatg gagtaaggaa tacccacttg
     7021 tttaccatct ttttcagaca gtgccatgat attgtctaaa aaatgatctt taaaataatc
     7081 agcattatcc ggatccactt cttctactaa agattgagga ttagtatatt tgaaattttc
     7141 tgcaaaataa tctttaaaag cccatcccac ttgtactacg tccggtattt ctttggaggc
     7201 aacagaagct tgtaaatttt gcatcaagcc tttatacata tcaggattat attttgctac
     7261 aaccttcact ttgtcttgag attgattgta tttatctact aattcattca ctgtttttcc
     7321 acctagggta tccgcattaa catgccaata ctctatcgtt acacgaccct ccgatttttt
     7381 tgttgtcttg gtattcccac taccacaagc tgccaaagag atgacactta aaacagacac
     7441 aacccctata acaagatttt tctttaacat aacattaact tcctcctaat ttctttatgg
     7501 ccatttttct aatcaagaaa tattatgaac taccaatgta aatttctagt taattttctg
     7561 taaataattc gaaatttgtg catttcgggg tacagggtca ctggacatat ccatcaagct
     7621 aagaataaag cccccatatg gtcatgtatc ccatctccaa atctcttaac tcctctgttt
     7681 tgattataaa atagtttatt ctgtgctcct ttcttccata aataggccca tgcacaacgt
     7741 gaggttatat tataaacacc acagcgcgca aggtactcaa tcgtttctag ttcattgact
     7801 gtccatacag aaaatgtcaa tcctagctgc tgccccactt cacgggccaa cttagttaac
     7861 catccttcat gaatattgac gatttgaacg ctttgatagg ctaatttctg taaggtatcg
     7921 atcaaatctg cttcggtaat atccccaagt tttttccctt cgaactgatt ttcaatatta
     7981 taaaatatat gctttcccca aatcgcagcc caagataatt gtacatagcc actaagaaca
     8041 atttgtggcc agatttgata ggtttgtgcc agcgaaaaaa cggccatttc caatccctct
     8101 tcttttaaat cacagttaat ggtcatggtt gccttctcat tggccactgc ttgaaacacc
     8161 tgctcaaggg ttaccgaatc tgggacaact tcttacctgt catgggctag tattagcgta
     8221 ccatctgttt gctgacgcac atctacttca aaacaaagct ggcgatccaa acaaaagcga
     8281 agaaatgccc agctattctc ctccgtattg tcactaccag agtgtgcagt gatcatggtc
     8341 attttgaccc ctcctttaat tccgtgattt tctcccacac gtccactata ccgatgaagc
     8401 gttaatttct tgttaatttc ttgtaaattc cctgcgtttt ttcagtaaac tagttgtaaa
     8461 tcttgcatgc tccttcctac gaactcatga atcgtcgatt ttgcccttct agctagtttc
     8521 accaattaag tagttctaca ttccccgctt ttaacctact acaccttttt ttgttttcag
     8581 ctattccttc ttcttgctga aagtccttga ggttctttct tacaggatac catcaaggtg
     8641 ttcaatggct tattcccatt gaatgaccga gacttactat cagatttctg ctcgttgaac
     8701 caagtctttg atacaggatt tcttccgtca tcttctcaca aataccacct tgcgtttctc
     8761 tagcgattgg tcgatgtgca ccctcccagt ggactgtcac tacccctttt tgctatgcct
     8821 agcccacaaa aaaagctgtc ctcacagaca
//
LOCUS       DADVXV010000098         8569 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.101, whole genome shotgun sequence.
ACCESSION   DADVXV010000098 DADVXV010000000
VERSION     DADVXV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.101"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            64..351
                     /locus_tag="KB969_002468"
     CDS             64..351
                     /locus_tag="KB969_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870392.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            767..2305
                     /locus_tag="KB969_002469"
     CDS             767..2305
                     /locus_tag="KB969_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBB6870393.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            2302..3267
                     /locus_tag="KB969_002470"
     CDS             2302..3267
                     /locus_tag="KB969_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870394.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            3254..4576
                     /locus_tag="KB969_002471"
     CDS             3254..4576
                     /locus_tag="KB969_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6870395.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      4639..4743
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4817..5560
                     /locus_tag="KB969_002472"
     CDS             4817..5560
                     /locus_tag="KB969_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6870396.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            5575..6567
                     /locus_tag="KB969_002473"
     CDS             5575..6567
                     /locus_tag="KB969_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBB6870397.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            6579..7316
                     /locus_tag="KB969_002474"
     CDS             6579..7316
                     /locus_tag="KB969_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870398.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            7306..8028
                     /locus_tag="KB969_002475"
     CDS             7306..8028
                     /locus_tag="KB969_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBB6870399.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8112..>8569)
                     /locus_tag="KB969_002476"
     CDS             complement(8112..>8569)
                     /locus_tag="KB969_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBB6870400.1"
                     /translation="AESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAE
                     QPVVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGR
                     YIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         2773 a         1467 c         1844 g         2485 t
ORIGIN      
        1 aggaaaatga aaaaaaatta tttttggctg tttcttttta tttatcaaat aaggagtgga
       61 aaaatgcgag cagcagactt attgacaatt cttacaaaat cacccaaaaa aacagagtat
      121 caaggagttt ttttggctca agaacaaaaa ctggtgcctg tgacaatggt ccagataaat
      181 aaagcaaatc aatttatctt tttatttgaa cacggcaaag caccacttgc tatgaaagac
      241 atctttcttt ttttgatgaa gaaccgtgag aaagctgttt attatcagtc aaaagaagaa
      301 ctcattcctc tttatggagt gaaagagata gaaaataaag tggtgatata agtaaaaata
      361 agaaaacaag acgtttatga tgtcaaaaca accatttttt acatttttgg caaaaaagtg
      421 tcatgataca gtataatatt cgttgaacag gccaataaag gtgttctccc ccacgagatt
      481 tctactttat tggctgtttc tttttattaa aataaaagtt gtgtgtgtaa aaaagatata
      541 gctgattcca agtgacaatt tcgtatagat ttttatggta ttcgtagtga aaaaacgaga
      601 accaaaaagt tgatccgact ttgttgcttg gattcttttt ttgtcagcat atttagaggt
      661 atttttttct tttttttgtt cgtgctgtaa ggttaaggca agacaagtta gttgggaaaa
      721 aggaaagaaa tgtttatact taaagaataa cagaaaggaa ggtcgcatga ataattttat
      781 acaaacatta agtgaaagaa aaggcgagtt gctggaagct gcatttcaac atctgtccat
      841 ttctctcatt tctttgctga ttgcagcact gattgctatt cctttagcga tttgggcagc
      901 caatcataaa aaaatggcag aagtcttatt gcagatcacg ggtgtgctcc aaacgattcc
      961 ttcacttgcc ttattaggtt tacttatccc atttgtaggg atcggaactg ttccagcatt
     1021 gattgcactt gttatttacg ctttgcttcc gattttccaa aacacgtata ttggtctagc
     1081 tgaaattgac ccgtctattg aagaagcagc ggtagcattt ggtatgtcca gaatgagacg
     1141 cttgctgaaa gtagagcttc ccatcgcatt acctgtcatt atctcaggta tccgaactgc
     1201 cttagtttta atcatcggta cggctacttt ggcagcattg atcggagcag gtggattagg
     1261 gacatttatt ttgttaggta ttgaccgaaa tacacctgtt ttgacattga ttggtgcgat
     1321 cagttctgcc ttgcttgcaa ttatattcag cggactgatt cgctggttgc agcataagaa
     1381 acctcgatat tccatcatta ctttagcagc agtggtgtgt ttatttggcg gcgtttcttt
     1441 atatcagtct gccttgttta aaaatgaaac catcacgatt gctggaaaat taggagcgga
     1501 acctgaaatc ctgatccaaa tgtataaaga attgattgaa gacaacacaa aaacagaagt
     1561 tgaattaaaa ccgaattttg gcaagacgag ttttttgttc aatgcactgg atcaaggtca
     1621 aatcgatatc tatcctgagt tcacaggtac tgtcctagaa agcttggtga aggtacctga
     1681 agcaatgaaa agtgctgatt tgacaaaaga aaaaacatat gacgaagcag aagaattatt
     1741 gaataagcaa ttcgatatga cattattaaa accaatggct taccaaaata cgtatgcctt
     1801 ggcagtcaag agatcttttg cgaacgaaca tcaacttaaa aagatttccg atttggcagc
     1861 tatctctgat cagatcaaag cgggattcac actggaattt attgatcgtt cagatggata
     1921 taaaggaatc caagaagcat atggcttgaa tttttcaagt gtacaaagca tggagccaag
     1981 tttgcgttac caagcaatca ataatggaga tgtcaatatt gtggatgcct attccacaga
     2041 tagccagctc aaggagtacg atctagtgac tctagaagat gatcgagggt tattcccagc
     2101 ttatcaaggc gcaccgctga tgaaaaaaga ttttgctaaa gaacatcctg aaatcgttaa
     2161 agcactgaat aaattaagcg gaaaaataac agaggatcaa atgattgata tgaattacca
     2221 agtcaatgtc gaaaagaaaa agccgacaga agtagcacga atcttcctga aaaatgaagg
     2281 attagtaaag gaggaagatc agtgactaaa ttaatcgagt tcaaacatgt gcaaaaaaag
     2341 tatgatggaa agtatgtcat cgatgaccta aatctggcaa tcaaaaaagg agaaatcttt
     2401 gttttggttg gtccttccgg tagtggaaaa acaactactt tgaaaatgat caatggatta
     2461 tctaaaccat cagcaggaga catctacttc aaaggaaaat cgttaaatga atataatctg
     2521 cagaaaatgc ggtggaatat gggatatgtg ctgcagcaaa tcgctttgtt cccgaccatg
     2581 acagtcaagc aaaatattga agtcatccct gaaatgttag gttgggaaaa gcagaaaaga
     2641 gcagaccgtg tagatgaact tcttcaaaaa gttggcttat ctcctgatat ttatcgagat
     2701 cgtatgccta gagagttgtc tggaggagaa cagcaacgga tcgggatcat ccgagctatt
     2761 gctgcaagcc cagatgtgat tttgatggac gagccattta gcgcattaga tccgatttca
     2821 agaaactcat tacaagaatt ggttttgtcc ttacacgaag aattgggcac gaccatcgtt
     2881 ttcgttacgc acaatatgga agaagcaatc aagctaggtg atcgtattgc atttatgaag
     2941 gatggagaaa ttatccaatg tgacacacca gagcagttat tgatgaatcc taaaaacgac
     3001 tacgttcggc atttctttga tgaaccgaaa cagacgaaag agtggcgagt agaagattta
     3061 gtcgtcaatg gatatttctt aaatgaaata ccagaaaatg ctcgtcaaca agtttgcttt
     3121 gatacgccta tgaaagaagt atattcgctt ctttcggtgt atccaagcat tgtgatagta
     3181 gaaaagcaaa gaagtattgg gtcgctgaca agtaaagaaa tctttgcttt tttaagtcga
     3241 gaggaggaag gaaatgaaaa catatgatgc aatcatcatc ggttcaggtg tgagcggctt
     3301 aagtgctgct tatggattga aagaagcagg taaaacagta ctagtggtcg aagaagatct
     3361 atggggcggg acttgtccta accgtggatg tgatcctaaa aaagtcttgt taagtgcagt
     3421 agaggcacgt aatcgggtaa aacaattgag tggaaaaggt tttaacgaga tcccaactgc
     3481 caactgggaa gaacttcaaa aattcaaacg aacatttacg gatccagtcc cagaaagccg
     3541 aaaaaaacaa ttagcagaag ctgaaatcga tcatctttca ggaaccgctc gttttttgga
     3601 tgattcatct attgaagtca acgaagaagt cttccatgcg gattacttag ttttggcaac
     3661 cgggcaaaga cctacgatct taccagtgga gggaaaggaa tacttgaaaa ctagtgcaga
     3721 ctttttatca ttgcctgtac tgcctaaaga aatcattttt atcggtggtg gttatattgc
     3781 ttttgagcta gctacgattg ccaatgctgc agggagcaaa gtaaccattg tccatcataa
     3841 tcaacggcca ttaaaagaat ttgaggcgtc tttggtagag gaagccgtcc atcaaatgga
     3901 agcatctggc attcagtttg cttttggtgt tgaaacccaa aagatcattt cagaaggtac
     3961 tcgctatcgt ttagtcggaa aagagacgga attagtagca gatatgattt tttgtgcgac
     4021 tgggagacag ccgaatacag aatctttagc acttgagcaa gcgaatatcg tctttgataa
     4081 acacggaatt gcagtcaatg attatctgca aacgagcaat ccaaaaattt ttgcgtgtgg
     4141 agatattgtt tcaaggaaaa ccccaaaatt gacaccagtc gccacttttg aaggaaatta
     4201 tgtagctaag cggataacgg atgcaacaag cgaacctatc aaatatccga ttatacctac
     4261 gatcgtctac gccagtccta aacttgctga agtaggagtt acaaaaagtc acgcctcttc
     4321 gtcagatcaa gtggtagaga tggatcttac cagttggttc acctatcatc gtgtcaatga
     4381 accagttgct aaggctgaat tgacctttga ccagcaaaat tatttgattg gtgctgcagt
     4441 gattagcgag caagcagacg aattgatcga tgatttgaca ctcgtcatca atcaaaaatt
     4501 gactaaaaaa gagttggata gctatatcat ggggtatccg acattggcaa gtgatctctc
     4561 ctatttattg aaataatcag catgataact aaagcgcttg ttgctttttc cttcttgtgc
     4621 tacactttaa aaaatgaata cctgtttctg gggatgtcgt agacgacatg agagtaagtt
     4681 gtgaacttag acccattgaa cctgtcagtt aatactggtg aagggagaaa catagcagac
     4741 gcttgaagcg ggttactatg tcgtgcccat ttcaagcgtt ttttgttatt catattagaa
     4801 gaaaggaggt aacaaaatga agaaaaatct ttatccagca gtcagtatgg cattcatttt
     4861 aattatttgg cagattgttg tcatagtttg gaaaatacct gcctttattt tacccggacc
     4921 tgctgctgta ttttctgcat tagcggcaga tgcacaagta ttactttccc attctgtcac
     4981 gacattaaat gaagcagtgc ttggtttggt aatagctagc gttctttctt ttattactgc
     5041 cttggcaatg gattattgga agtttttaga aatgtctttt tatccgttac tagtgatttc
     5101 acaaatgttg ccaatcatgg tgttagggcc attacttacc ctatggtttg gtttcggtat
     5161 gcttccaaaa gtgatccttg ttgtcttgat aagctatttt ccgatcgtag tttctttttc
     5221 ggatacattg aggaaagtat caaaagagca aatcatcttt ttgaaaacga tgggggcaga
     5281 tacagggaag atttatcgaa tatataaaat accagcgggt ttatccggct tcttttccgg
     5341 tttaaaagtg gctgctactt attgtgtcag cggagcagtc gttggagaat ggctaagcgc
     5401 tcaagcaggc ttagggtatt acatgatacg cgtaaaaaac agctaccaga tcgataaagt
     5461 ttttgctgcg atcatttgtg tcattctatt gagtttattg ctgaatggcg cttgttcatt
     5521 attgaaaaaa gggtattatc gtatgcttta tattttttaa gagaagggga tcaaatgaaa
     5581 aaattatggc ttttattacc gctactgttg cttttatccg cttgtggcac tgcaaaagaa
     5641 acaagtagca aacaagaaat aaaggatttg aaaaaagtga cacttgtttt ggattatgta
     5701 ccgaatacta atcatactgg catctaccta gcaaaagaaa aaggctatta taaagaggct
     5761 ggtttaaatg tccaaatcat cgaaccagga gataattcga caagtattgg tctagtaggt
     5821 gcggacaaag cacaatttgg tgtaagttat caagaagatg tcacttatgc tcacgcagat
     5881 ggacagaata taccagtcaa agcaattgct acagtgatca aacataatac ttctggattc
     5941 gccaccctat cagacagtaa catccattca ccaaaagatt ttgaaggaaa aacatatgca
     6001 ggttggcaaa gtccaagtga agaagctgtc ttaaaagctg tgatggaaaa agacggcggg
     6061 gacttttcaa aactgacaat ggtaggaagc aatggagaag ggccagaaag cttaggaaaa
     6121 tcctcagata tccaatggta ctttgaaggt tgggatatga tcaaagcaaa agaagcgggt
     6181 attgaactaa actatatccc attgaaagaa ttagatgaac ggttagatta ctatactccg
     6241 gtaattatta cgaatgatca actgatcaaa agtgatccag aattggtaca gtcttttatg
     6301 gatgccacga aaaaaggcta tcaggaagct attaaggatc caaatgacag tgctaaactg
     6361 ttgcaaaaat atgcaaaaga aaatgatcgg acgtttttag aagaatcaca agcattcttg
     6421 tcaaaaaatt atacggatga tcctgagaat tggggattga tggaagaaaa agtttggcgc
     6481 aattatacag cttttatgca ggaaaacgga ttgatcaagc aagatgtacc ttcgcaagaa
     6541 ctattcacta atcagtttat aaaataggag tgatagatat gtcaatccaa atcagccact
     6601 tgaatgtagt cattgaaaac ctgaaaatat tagaagacat ccatttcact atccctaaag
     6661 atacctttac atcgattgtc gcgccaagcg gagccggtaa gtcaacattg ctgaaaactt
     6721 taacaggagt ccagcctatg acttctggaa cgatcaaagt agacgatcaa aaagtaactg
     6781 gtctccatac agcatttagt tatatgccgc aagaagatat gttacttcct tggctgagcg
     6841 tctatcaaaa cgttacgtta tatcaaaaaa tcaatcatct aacaatcaat gaagaacaag
     6901 taagggatta tctggatatc tttgggttaa acggctatga acattttttg ccggaacaat
     6961 tatctggcgg gatgaagcag cgaacggcct tgttacgaac aatcatgaat ccttcttctt
     7021 acttgcttct tgatgaacca tttggagcgt tagatgctat gaccagaggg cagatgcaag
     7081 actggatgtt gaagctgcct aaaaaagcaa agcggactac tttacttgtg acgcatgata
     7141 tcgaagaagc aatttattta tcagacagga ttcttgtgct ttccgcccgt ccggcacatg
     7201 tgattgctga gattcaagtg cctgaaaaac gacggtcacg tgaatggcta ctgcagcaat
     7261 cagagttgaa gcaaacgatt tatcagttat tggcaggtga attagatgtt aagtgatgct
     7321 cattgtcatt tagatgggag tcagagttta gcactccttc agcaggaaca cacgattttg
     7381 acgatcatca attgtgattc gccagaagaa tggaaggaaa acagacagct tgcagcaagt
     7441 aagactcaag ccttaagtta cggtatccat ccttggaaag cagatagcta tacgtttgaa
     7501 caagttgagc cttttttgaa aaaagcaagg atcatcggtg aaatagggtt agataatatt
     7561 tggacgaatg taccgatgac tacacaaaaa aaagtatttg agcgacagct tgcttttgca
     7621 gccataaatg agaaacctgt tgtactgcac acaaaaggat gcgaaaaaga gatcttaaat
     7681 tatatccaag cttaccctaa tcactatttg atccattggt attcttcttt ggactatcaa
     7741 caagactata ttgatttagg ctgttatttc agcattggtc ttgatttgaa aaagaatcca
     7801 gcagtctggc aactagctaa agcagtccca atcgaccact tacttattga aacggatgga
     7861 ctacatgcag cagagtgggc tttagggggg attttttcag aaaaagatta tgtctcactg
     7921 cttgaagaac agttaaagac aatcgctgag atcaaagagc tatcagttga agaagttaaa
     7981 aaaaatactt atcaaaactt ggaacgtttc attagattag gtaaataaaa aagagatgtg
     8041 acacaactag tgtcgcacct ctttttggct ttctttgtat aaaagtaaac tgtttgatta
     8101 ataaatgaat cttagtacca accgtttgct tcccagaatg ctttcgccgc ttcccaagaa
     8161 ccataacgtg aagtaacata ttgttctgct actctttctt ggtttgcagc agagtagtca
     8221 ccatttaagt aagaagaatc taattggtaa cgtccgatgt aacgtccgtt cgttgctgtg
     8281 taagaaccgc ttgattcttt ttgtgcgatc cattcttttg cagagcttgt gcttgctgga
     8341 gtagcagcag tttctgttac agcaggagca ggttgtgttt cagcaacagg cgctgcttgt
     8401 ttttccgttt gaaccgtttc ttgtacaaca ggttgttcag cttggactgg tgcttcttga
     8461 acggctgctt gaggttcagc agctgcttgt gcagagcctt ctgttgggat tgttaattgt
     8521 tgtcctgagt aaatcaggtt aatatcagaa attgaatttg attctgcaa
//
LOCUS       DADVXV010000099         8435 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.102, whole genome shotgun sequence.
ACCESSION   DADVXV010000099 DADVXV010000000
VERSION     DADVXV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.102"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            625..1488
                     /locus_tag="KB969_002477"
     CDS             625..1488
                     /locus_tag="KB969_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6870401.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1617..3239)
                     /locus_tag="KB969_002478"
     CDS             complement(1617..3239)
                     /locus_tag="KB969_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBB6870402.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3488..4009
                     /locus_tag="KB969_002479"
     CDS             3488..4009
                     /locus_tag="KB969_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6870403.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4195..5925)
                     /gene="spxB"
                     /locus_tag="KB969_002480"
     CDS             complement(4195..5925)
                     /gene="spxB"
                     /locus_tag="KB969_002480"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBB6870404.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            6090..6908
                     /locus_tag="KB969_002481"
     CDS             6090..6908
                     /locus_tag="KB969_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBB6870405.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(7011..7208)
                     /locus_tag="KB969_002482"
     CDS             complement(7011..7208)
                     /locus_tag="KB969_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870406.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7377..7955
                     /locus_tag="KB969_002483"
     CDS             7377..7955
                     /locus_tag="KB969_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6870407.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            8050..8187
                     /locus_tag="KB969_002484"
     CDS             8050..8187
                     /locus_tag="KB969_002484"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870408.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
BASE COUNT         2536 a         1521 c         1660 g         2718 t
ORIGIN      
        1 aaaaccgtgt cacagtccct ttttccgaac aaacggtgtt caaaagcttg catctacggc
       61 actaagccca atcagatgaa aaatatggag tgctattttt atctgattgt tcttactgct
      121 tgatgcagag cagctttttc acaacctctc cactaaacgg tgttctcctg ccaactcctc
      181 ggtcacaagt cacaatattc aacaaacatg agaagctgtt ttttgaaatt gttccttgtg
      241 actcggagct aaacggcagg ctcacaacct cttggtaaac ggtgttcaat cagctgaccc
      301 tcggtattag ctcaaaaaac ggcaaaatat gaggaactat tttttccgtt tttttctcta
      361 atactcaggt caaaacgctg atttcacaac ctctgattca cggtgttcca gaagtagctt
      421 ctacggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct
      481 tatttcttga agctgaccac ttctgtcaca acctcttatt ttgattagaa cttgcgaaaa
      541 taaaccggtt aaagtgtgtc tagcgcaaga gatttgctat aatagacgat aagggtaaaa
      601 tgtaacgaga aggggttgaa aaatgtgtat caaattgtaa cagattcttg ttgtgatctg
      661 ccataccatg tattagcaaa agaaaaagtt gattttttat caatgaatct ccaattgaat
      721 gatcaagagt tagtagatga cctcggaaag acattcaatt atgaccgcta catgaatcag
      781 ctgaaaaatg gtgcgatgcc tacgacatca caaatcaatg ttggccgata tttagaattt
      841 ttccgttctt atgcggaaaa acagattcct gttttatatg tggctttttc cagtggatta
      901 agcggctctt acagtagtgc gcttcaagcg gttgaattgc tgaaggaaga atatgaagac
      961 cctgagatct atgtttttga tacaaaagct gcaagtattg gggaagggct tttagtattg
     1021 gaagctgtaa gattgaaaaa agaaggtaaa agcatcgaag aaaccctaga gtggctggaa
     1081 agtaattatt tgaaagtcca ttcatgggta acagtagacg atctgaaata tctagaacga
     1141 ggcggtagga tttccaaagc aagtgctact cttggcagtc tattgagtgt aaagcctatt
     1201 attacggtgg ataaagaagg aaggctgacg aatgttgaca aagttcgagg aagaaacaag
     1261 tcgatccaga caatcgtcaa tgagacggta aaaacaatcg ttgcaccact tgatcaaatc
     1321 gtttatgtgg cttacgctgg ggatctagag agcgcggaga aggcaaaacg gcttttggaa
     1381 gagcagataa agatgaaaga tgtgaagctt tatcccttag gaccaacgat cgccagtcac
     1441 acaggctatg gctgtatcgc gattttttcg atgggaatca gtcgataaaa gcagtaactc
     1501 attctgtaaa aaagcccaga aattgattgt aacaaaaaca gcgactctta aaagatagat
     1561 gagcatccta tctcttagag gtcgctgttt ttttattttt taagctaaat aggccattat
     1621 gcccataact cgttcaattg tttttgaata tctgcatttt ccaaaaattc atcatatgtc
     1681 gtatcagctc gatcgatcac acctttatcc gaaacggcaa tgatgcggtt tgccaatgtt
     1741 tggataaatt gatggtcatg tgacgcaaat aagattgagc cagtaaatgc catcaagccg
     1801 tcattcaatg ctgtgattga ttctaagtct aaatggttcg ttggatcatc taatacaagt
     1861 acgttagctt tcgaaagcat catttttgaa agcatgcaac ggactttctc tccaccagat
     1921 aaaacattca ctggtttcaa tacttcttca ccagaaaaca acattcttcc taagaagctt
     1981 cttaagaagg tgttatcatc ttcttcttta cttgcatatt gacgcaacca gtctaaaatc
     2041 gttagatcag tatcgaattc tttcgttgta tcctttggta aataagaatt acttgttgtc
     2101 acaccccaac gtactgttcc agtatctggc gtaatttcac ccatgataac tttgaatagc
     2161 gttgttgttg ttatatcatt ttctgcgacg aaagcgacct tgtcttcttt gctcaaatta
     2221 aaagatatat catctaaaat tttctttcca tcaatcgtta cacttacatt ttctacctgc
     2281 aataagtcgt ttccaatctc acgttcaggt ttgaatccaa cgaatggata acgtctagaa
     2341 gaaggttgga tatcgtctaa agtaattttt tcaagcattt ttttacgtga agttgcttgt
     2401 tttgattttg atgcattcgc actaaagcgg gcaataaatt cttggagttc tttgatttgt
     2461 tcttcttttt tggcatttgc gtttgcttga agtttagccg ctagttgact agattccaac
     2521 caaaaatcat aatttcctac ataaagtttg attttaccaa aatctagatc cgccatatgt
     2581 gtacatactt tgttcaaaaa gtgacggtca tgggatacaa cgatcacagt attttcaaaa
     2641 ttgatcaaaa attcttccag ccaattgatc gattggatat ccagaccgtt tgttggttcg
     2701 tctagcaaaa gaacatcagg tttaccaaat agtgtttgtg ctaataacac ttttaccttt
     2761 tgtccaccag ttaattcact catttgctga tggtgcaatt cttcagggat gttcagacct
     2821 tgcagtaaaa cagctgcttc tggttcagct tcccatccat taagctcagc aaattctcct
     2881 tctaattcag ctgctcgaat accatcttcg tcagtgaaat cctctttcat gtaaatcgca
     2941 tctttttctt tcagcacttc atacagacgc ttgtgtccca tgatgactgt ttcaagtaca
     3001 gtatagtctt catagtcgta atggttctgt ttcaatacgg ccatccgttc atctggtccc
     3061 atagtaacgg aacctgtgga aggctgcaga tcccctgata acactttaag gaacgttgat
     3121 ttacctgcac catttgcacc aatcaagcca tagcagtttc cgggggtaaa tttaatattc
     3181 acatcatcaa atagtttgcg gtctgaaaag tgcaaactca catcatttac agtaatcaat
     3241 ttttttcctc acttttatca ttattagttt tgacaagtct tatagaatta tataggggaa
     3301 aggtaaaaga ttcaaggcaa tcgaacattc tttgtgtttc acgtgaaaca gaatgaaaaa
     3361 aataaaaata aaagcggagc gaaaatagct actataggat ttattagttt gcaacagcat
     3421 aatttttgac gttatttata agagggagta ctataaaact gtaaaagaaa tgaaagaagg
     3481 attgaaaatg gatgaaaaaa gaaccatcga ctggggctca ttgattttgg gaattttatt
     3541 tgtacttgtc tcattgttat catttcaaga ccctgtcgga aatttagttg caattgtagt
     3601 agtctttgcg atttttgcct ttattaaagg gatatttgaa ctgtttgtac ggaacagatt
     3661 aaaagagcta acaggatata aaggaaagat gcccttaata atcgggatca tcgatattct
     3721 agttggcgtc tttttcttat tcaatattgg tgcaggagtc gcagcattgc cttttgtttt
     3781 tgcagtatgg tttattgctg attcagtttt agcgttattt actgctgact tggcaagagg
     3841 agtaagtgaa ggatattatt ggtttacgat catcgtcaat attttaggaa ttttattagg
     3901 aattttctta ttgtttaatc caatttcttc tgcgttgaca ttaagctttt tagttggatt
     3961 ctattttatg ttatttggta tcacacatat cgtctatgca tttagataag taaaatcaaa
     4021 caaataaaaa agccggcttc cgattacagt tttactgttg taattggaag ccggcttttt
     4081 tatcatggac aaatatgcac gaggtgattt ttaggtgtcg agacaaattt atgcaaaaat
     4141 gtgagaagct atatacacaa attttatctt aatactcgaa gcatagcgca gttgtcacaa
     4201 cctcttttca tataattcat tcaatactgg caaatcatgg acttcatatt tttctttgaa
     4261 tgcttggatt tcttcttcag aatattttct tggatctaaa tgcagatctt ctactggcaa
     4321 tgggcgcttg ttattgatct tcacatcgat tactacagga cgatctgatt ttgcagctgc
     4381 atcaaaggca aatcgaagtt gcgagtattc tgtgactgta aagctatttg ccccgagcgc
     4441 ttctccaact ttaccgaaat ctgcatcttc taaaaataca ccaaatttct tttgttccgt
     4501 atcttcttgt tctgcttcga tgaaaccaaa agaatcattc gaaaagacaa cattaataat
     4561 tggaagctga tatttgactt gtgtaatgat atcttgcatg accatagcaa acccgccatc
     4621 accacttaag gtaaatactt gtttttctgg gtagcttagt tgtgcggcaa ttcctcctgg
     4681 cacaccatta cccatagttg cgaaccatcc agatgtcgta tgtttttgtt taccgttcat
     4741 attcaataaa cgaatagaat ggatagtcgt gttaccgaca tctgtgacga aaatcgcatc
     4801 gtcttcagca atacgattga tttctttata gacagcctct ggacgaatcg gttcttcctc
     4861 tcgatcttca aaagatttca accaatttac ccatttttct ttattttctt gatttgctag
     4921 gtaccagcta tcagcagggc gagcatcccc taactcgaca agtctttgca aagctgtgtt
     4981 tgcatcaccg aggatcgaca aagatgtttc atggcgtcgt ccaaattttg acgcatcgat
     5041 atcgatttgg ataaattcag cagttggatt aaaaaatgca cgtccaaatg ggaagtcgct
     5101 accgacaaat aagatcagat cggcttctgc caatgcttca tttccgggtt tagtagcgac
     5161 acgtccagca aaaccaagaa agttttcata atcatcagga ataattcctt ttgctagaac
     5221 ggaagcgaca acaggaactg aaaaatgttc tgagaattct ttgatttgcg gaaatccgtt
     5281 tcgcgttcct tgaccaacat aaagaactgg tttttttgct ttttcaagat aaggcaaagc
     5341 agctagcaaa tctttttctt ctggtaatat cacacttgtt ttgtgagtgt gagcggtgga
     5401 gaaaggttgt tcgtcaattt cttcaaaacc aagatcaaca gggatagtca cgatagccac
     5461 gcctttatgc tcataggcgg ctttaatggc ttcatctact acatgcggaa gactttgtgg
     5521 tgtcatgact gtacgattgt atacgctaac atctgcgaaa ataggatttt catttagttc
     5581 ctggaaagag ttatagttca tggatgtaga agcaacttgt cctaagaacg ctactagagg
     5641 cacatggtcc atctgtgcat catacaaacc attgatcaaa tgtgtcgcac caggtcctgc
     5701 agagccgaag acagcgccga ctttccccgt taattttgca tctgcagcgg ctgcgagtgc
     5761 gccgacttct tcatgacgaa cttgaatgta gttgatttcg gttttttctt gatatagcgc
     5821 atccataatt gaattgaaag atcctccggg aatgccgtaa atatggtcga taccccagct
     5881 ttcaagaact tttaccattg cgattcctgc attgattttt gacatggtgt ttcactcctt
     5941 tagcaatgat gatacataaa ttttttgtat ctagagtata gaacttttta tcgaaaatcc
     6001 caactaattc gtcttttcac aaaaatgtag tcatgttttt gggaatatgc tagagtagta
     6061 catagataga ttcaagagag gggaatggca tggttgaatg gctattgaga cttgaacctt
     6121 ggcagcaagc acttgctggg acagctttta cttattttat gacagctctt ggtgccgggt
     6181 tggttttttt ctttaaagaa atcaaaaaag aagtgctaaa cttgatgtta ggatttgctt
     6241 ctggtgtcat gattgctgca agtttttggt ctttgttaga tccggctatt acaaaagcag
     6301 aagaaaatgg agatattgct tggctagttg taagtattgg gtttggttta ggcggtgtgt
     6361 ttttatatat ggcagataaa acactgcccc atatgcattt tggaccacaa catgaagcag
     6421 aaggattgcc tacccattta aaacggacga tcttgcttgt tttttctatt acattgcata
     6481 acattcctga aggtttagcc gtgggggtag cattcggtgc agcagcaact gcggataatc
     6541 cgacagccgc tatattagcc gctgtttcgg tggcgctagg tattggtatc caaaacttcc
     6601 cagaaggagc agctgtatca atcccgttgc gacaagaagg tctgagtcgt aaaaaggcct
     6661 ttgtttacgg acaagcttct ggaatcgttg aaccaattgc tggagtgatt ggagcgctac
     6721 tagtaacgaa agtggagctg ctgcttcctt atgcacttgc ttttgccgca ggagcaatga
     6781 tttatgtcgt ggtggaagaa ttgatccctg aagcacagca gacattgtcc agcaaacgtc
     6841 attttgcagt ttttggcgtc atgagtggat ttatcattat gatgattttg gatgtggcat
     6901 taggataaat aaaaaaaata tatatgatat atcaaatagg gccgcgaact tatatcgcga
     6961 ccctattttt ttagtaagtt atatcataat gaagtgaatg gtatcataca ttaataatag
     7021 ttttttctat gtgtatttcc tttgatccag cgaacaagcc agatgataag tgcgattggg
     7081 attagaactt tgaccgcaaa ccataaaagc ccgcttagga cactgacaaa aagactgatg
     7141 acgaagctag ctgcaattag cactaaaaga accatgaaga tatttaagaa catatttttt
     7201 tgacgcatac aaaaccctcc tcttgttcat tctttactat agaaaaagta taacagggat
     7261 tgtttaaaaa cacctccaac tgaagactga tttttacttc atctacttaa atgatcaaac
     7321 aattgctttt tctctggttt atcatctaaa atagagcgga aaaggaggag aatatcatgc
     7381 ctaaaaatcg tcttgaagca tttacagatg ctgtaatcgc gattatcatg actattttag
     7441 ttttagaact tcatgaacct aacggagaca cgtgggaggc gctcgctgca ttaggttacc
     7501 gattttttat ctatattgtc agttttatca ttttagcgat ttattggaac aatcatcatc
     7561 atttatttca agttgtacat aagataaatg gacgggtctt atgggcgaac agtttctttg
     7621 tttttgcgct ttcgcttttt ccgtttgcaa cttcatggat cagtgagtac atcaatagcc
     7681 tggctccaga aatgacttat ggttttgtta ccttgaccgc taatattgcg tattatatct
     7741 tggcaaaaga acttgtcaaa gcaaataaag gccacgagaa agcattgaag gcgatgttga
     7801 ataattacaa gaaatcgtat ctatcgattg gtttgaatgt gttaggaatt gtcttagggt
     7861 atttagtagc gccagtagcc gtgctgatcg caaacatcgt gattctagct gcttggatca
     7921 tcccaagtcg taccatcgaa tcacaatatc ggtaaaatga tccgtgttta aaatttaaga
     7981 gaaaaatata gaaaaaataa ataaacgatc aaatatccga gtgatactag tattcaaaga
     8041 gggatgcaga tggatcaaaa aagaattcat gtaggactga ttactagttt tgtcacgatg
     8101 cttatttatt tggatcaagg tcatttgact tggacagtag ttggtgtcgt aggatttttg
     8161 acattattca cagcaataaa aaaataaaca tctttatgta atctgatgtt ctatctattt
     8221 aagaaaagca tgtttacagc agtatgattc tgttgtaaac gtgtttttat ttgtggaaaa
     8281 tttaattttt agaaaagtgt atcgaaaaat agatagttag tttttccaca gtggataact
     8341 tcgtaagaga taaaaataaa aaattagtca aagaagggcg tatagatttc ttttgatagg
     8401 agatatacaa cagaaatgaa taaatattaa cgtgt
//
LOCUS       DADVXV010000100         8350 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.103, whole genome shotgun sequence.
ACCESSION   DADVXV010000100 DADVXV010000000
VERSION     DADVXV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.103"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..179
                     /locus_tag="KB969_002485"
     CDS             <1..179
                     /locus_tag="KB969_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870409.1"
                     /translation="NLKTGAIITEKEFKNLVTEEESRFYNLSGNICPGFMDQIIENES
                     IESIENYVPVDLPK"
     gene            complement(352..534)
                     /locus_tag="KB969_002486"
                     /pseudo
     CDS             complement(352..534)
                     /locus_tag="KB969_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            521..718
                     /locus_tag="KB969_002487"
     CDS             521..718
                     /locus_tag="KB969_002487"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870410.1"
                     /translation="MKDSIVEPEGMENTFELYNKTTVDKLIPILVPTDLNGHDVLLRF
                     NGFLGEDYRYLKISDPQPLTE"
     gene            complement(761..1336)
                     /locus_tag="KB969_002488"
     CDS             complement(761..1336)
                     /locus_tag="KB969_002488"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBB6870411.1"
                     /translation="MAQLFYRYGTMNSGKSIELLKVAHNYEEQGKRVIIMTSAIDTRS
                     GFGKVESRIGVSKPAIAITSEMDVYGELVEIIDQYGKVDCILVDESQFLSRENIIDLS
                     LIVMNEEVPVICYGLKNDFQNNLFKGSEALLTFADKIEEIKTICHFCNKKAVMNARIV
                     DGIPVYSGEQIVVGGNEDYLSVCRNHYYNED"
     gene            complement(1491..2017)
                     /locus_tag="KB969_002489"
                     /pseudo
     CDS             complement(1491..2017)
                     /locus_tag="KB969_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2474..3985
                     /gene="gadC"
                     /locus_tag="KB969_002490"
     CDS             2474..3985
                     /gene="gadC"
                     /locus_tag="KB969_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015082498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate:gamma-aminobutyrate antiporter"
                     /protein_id="HBB6870412.1"
                     /translation="MNKKKLSLFGFFALTASMVLTVYEYPTFATSQLHLVFFLLLGGI
                     LWFLPVALCAAEMATVEGWKDGGIFSWVSQTLGERFGFAAIFFQWFQITVGFITMIYF
                     ILGALSYVINFPELNTDPFIKFIGVLVIFWVLTFSQLGGTNRTAKIAKAGFVIGIVIP
                     SIILFGLAAAYFIGGNPIQMAINAKAFIPDFSQLSTLVVFVSFILAYMGVEASASHIN
                     ELENPQRNYPLAMFLLVILAIALDAIGGFSVAAVIPQHDLSLSAGVIQTFETLILHFN
                     SHLHWLVKVIALMIACGVMGEVSSWVVGPSRGMFAAAQRGLLPVFFRKTNKQDVPVPL
                     IMIQGIIVTIWAAVLTFGGGGNNLSFLVAISLTVVIYLVGYLLFFLGYFVLVFKKKDL
                     KRTYNVPGKTVGKTIIGGIGFILSVFALLISFVPPASIAASEHRTYQIILLISFVVTV
                     LLPFIIYEVHDKSAHTTIEEPTHVKAEDVNPAVYPAARGEHHVTKNDEHILKH"
     gene            3998..5398
                     /locus_tag="KB969_002491"
     CDS             3998..5398
                     /locus_tag="KB969_002491"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBB6870413.1"
                     /translation="MLYGKDNQEEKNYLEPIFGSASEDVDLPKYKLNKESIEPRIAYQ
                     LVQDEMLDEGNARLNLATFCQTYMEPEAVKLMTQTLEKNAIDKSEYPRTTEIENRCVN
                     MIADLWHAPNNEKFMGTSTIGSSEACMLGGMAMKFAWRKRAEKLGLDIQAKKPNLVIS
                     SGYQVCWEKFCVYWDVELREVPMDEKHMSINLDTVMDYVDEYTIGIVGIMGITYTGRY
                     DDIKGLNDLVEAHNKQTDYKVYIHVDAASGGFYAPFTEPDLVWDFQLKNVISINSSGH
                     KYGLVYPGVGWVLWRDQQYLPEELVFKVSYLGGEMPTMAINFSHSAAQLIGQYYNFVR
                     YGFDGYRDIHQRTHDVAVYLAKEIEKTGIFEIINDGSELPVVCYKLKEDPNREWTLYD
                     LSDRLLMKGWQVPAYPLPKDLDQLIIQRLVVRADFGMNMAGDYVQDMNQAIEELNKAH
                     IVYHKKQDVKTYGFTH"
     gene            complement(5563..6998)
                     /locus_tag="KB969_002492"
                     /pseudo
     CDS             complement(5563..6998)
                     /locus_tag="KB969_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328084.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            7391..7984
                     /locus_tag="KB969_002493"
     CDS             7391..7984
                     /locus_tag="KB969_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBB6870414.1"
                     /translation="MNKDITFPVMDVRLVPITKIQANDYNPNRVASPEMNLLELSIIE
                     DGFTQPLVCYYKEKEEKYILVDVLHRYRVAKERLNLKVVPVTVIDKPIEERMASTIRH
                     NRARGTHEIRGMEIVIQRLVKNGWSDKRISKELGMDIEEIFRFKQVSGGMATVFLTNF
                     IRCRTSFRMLFRLSLTMSLLGCDDLRQELTVKVRLPR"
     gene            complement(7968..>8350)
                     /locus_tag="KB969_002494"
     CDS             complement(7968..>8350)
                     /locus_tag="KB969_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBB6870415.1"
                     /translation="FSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKG
                     CPFDNAVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVG
                     YRNQRLAQRILDNELGCANASEAV"
BASE COUNT         2627 a         1415 c         1516 g         2792 t
ORIGIN      
        1 aaaatttgaa aactggagct attataactg aaaaagaatt taaaaattta gtgactgaag
       61 aagaaagcag gttttataat ttgtctggta atatttgccc tggatttatg gatcagatta
      121 ttgaaaatga gtcaattgaa tcaattgaaa actatgttcc tgttgactta ccaaaataga
      181 aaaaataatc ctgtttttac agtgaattat tttaattttg attttcaata aaaatatatt
      241 acaataataa tcgtaatagc taatgaaaca atttctcaat ctttttacca ctccaaacag
      301 ggagcgtcaa taattttgtg taaataactc gtccttctgc aaaataatgg gttactcagt
      361 aaacattgaa gctaatgtat ccgtcacttg ttggaagcct ttatggcttc tatttaagaa
      421 tttttgattg tatgtatcaa agatggatac taggaaacgc tctagtgatt cttcattttg
      481 aaactgctct tttctgcggc tgtatttctt gatttgttta ttgaaagatt cgattgtaga
      541 accagaagga atggagaaca cttttgaact ttacaacaaa actactgttg ataaattaat
      601 tccaatttta gttccaactg atttaaatgg tcatgatgtt ttacttcgtt ttaacggatt
      661 tttaggtgag gattatagat acctaaaaat ttctgatcct caacctttaa cagaataata
      721 aaaaacgtgt aatcaattat ttgattacac gttttttatt tcaatcttcg ttgtagtagt
      781 ggttgcgaca taccgaaagg taatcttcat tacctcctac tacaatctgt tcacctgaat
      841 aaactggaat accatcaaca atacgagcat tcattacagc ctttttattg caaaaatggc
      901 aaatagtttt aatttcctca attttatcag caaatgtcaa taatgcttcg gatcccttga
      961 agagattatt ttgaaaatca ttcttcaatc catagcaaat tactggtact tcctcattca
     1021 ttacgataag tgatagatca ataatattct ctctacttaa aaattgagac tcatcgacca
     1081 aaatacaatc aacttttccg tactgatcaa taatctccac taattctccg tacacatcca
     1141 tttcagaagt aattgcaata gctggtttcg aaacacctat acgactctca acttttccaa
     1201 atcctgatcg agtatctatt gcgcttgtca ttatgataac tctcttccct tgttcttcat
     1261 aattatgagc cactttcagt agctcaatac tctttccact attcattgtt ccatatctgt
     1321 aaaataattg tgccattaaa tttattccct tcttttacaa ttcaattatt ccttaattcc
     1381 atctgctttt atgcagctgc tcgtttattc cttgatatgt ctataacatc tactatccct
     1441 aaaaccaatt tataagccat tagagatggt attcctgaac atctctcata ttgttttttg
     1501 agtggtatat catctgaaaa actgaaggaa tcatgaaaat agcgacatac ttatcattta
     1561 gagttctaac tttaaatgca tttacttctt cagtcagcac tttagtcatg ttggacatgg
     1621 tttggggcgt gtagtgatgc ccatacattt tctcaatcaa gtctgcgatt tccgacatgg
     1681 taataccttt tcggaagagg tgaatgacgg tctcctctaa tgtgtcattc gtccgtctat
     1741 aagcaggaac agtctgttgc ttgaactcgc cattgcggtc gcgcggaatc tggagatgaa
     1801 gttccccata ctcggtcttg accgtacggt cataggagcc gttacgagaa ttacccgtgt
     1861 taaaaccaat gcgatcgtac ttttcgtaat cgaggaaagc cgttaactcc gttttgagaa
     1921 gcgtattgac agctttttcc aaatggacac ggaataatcc attcaaatcg cctttgttcg
     1981 ctagagtctt taggatttct gtagtaaaat cgttcatatg gaagtcctct tttctgtgaa
     2041 tgtgttgtgg taactctatt ctacagaagg gacttccttt tttctattta cacaaaatat
     2101 tttacactct caacaaaagt atcttcgatt aatacttgct caagttatgt gcagctacga
     2161 aaaagtaggt accgaggtac tttctttttc gcagcttttt ttggacttat gagaagtaca
     2221 ttcgctggaa gaatacgata taaaacgagc tttttcacta aagatattaa tagagtgaaa
     2281 gaaacaagct tttgttgtca gttttttcac ttttctaaaa atgaaaataa aaaattctgg
     2341 aagtggagaa gaattttgct tgctatactt tgtcttgtag aaaagaggta gacaaaataa
     2401 tgcaagctca aataagcgat tttccataac cttggtagga atgacaaatt aaataggaaa
     2461 gggaagtaat aatatgaata aaaaaaagtt atctctattc ggtttttttg ccctgacagc
     2521 ttccatggtt ttgactgttt atgagtatcc gacctttgca acatcacaat tacatttggt
     2581 tttctttctt cttttgggag gtattttatg gtttctacca gttgctttat gtgctgcaga
     2641 aatggcaaca gttgaaggat ggaaagatgg tgggattttc agttgggtta gtcaaacttt
     2701 aggagaacgt tttggttttg cagctatttt tttccaatgg tttcaaatta cagtaggttt
     2761 tattacaatg atctacttca tactaggagc gctgtcgtat gtaattaatt ttccagagct
     2821 taatacagat ccatttatca agtttattgg tgtattagtc attttctggg tactgacttt
     2881 ttcacagttg ggcgggacca atcgtaccgc taaaattgct aaagcaggat ttgtcattgg
     2941 aattgttatt ccttcgatca ttctctttgg tttagcagca gcctacttta tcggcggtaa
     3001 tccgattcaa atggctatta atgcgaaagc ttttattcct gacttttctc agctttcaac
     3061 tttagtagta tttgtatctt ttatattggc ttatatgggc gtagaagctt cagcatcaca
     3121 tattaatgag ctggaaaatc cccaaagaaa ctacccattg gcaatgtttt tactagtgat
     3181 tttggccatc gccttagatg caatcggcgg tttctcagta gcagcggtta ttccacaaca
     3241 tgacttgtct ctcagtgctg gtgtaatcca aacatttgaa acgcttattt tacattttaa
     3301 cagtcattta cattggttgg taaaagtgat tgctctcatg attgcctgtg gcgttatggg
     3361 tgaagttagt tcttgggtag ttggtccatc acgagggatg tttgcagctg ctcagcgagg
     3421 tctgttacca gttttcttcc ggaaaactaa taaacaagac gttccagttc cgttgattat
     3481 gatacaagga attatcgtta ctatttgggc agcagtctta acttttggtg gaggaggcaa
     3541 caatttatca ttcttagtag caatctcctt aactgttgtc atttatctcg taggatattt
     3601 actatttttc ctaggttact ttgtattagt ttttaagaaa aaagacttaa aacgaactta
     3661 caatgtacca ggaaaaactg ttggcaaaac gattatcggt ggaattggtt ttattttatc
     3721 agtgttcgca ttgcttatct cttttgtacc accagcttca attgcagcta gtgagcaccg
     3781 aacataccaa atcatactac ttattagctt tgtagtgact gttcttttac cttttatcat
     3841 ttatgaagta catgataaaa gtgctcacac aactattgag gaacctactc acgtgaaagc
     3901 tgaagacgtt aatcccgctg tttatccagc tgctagagga gagcaccacg ttacaaaaaa
     3961 tgatgaacat attttaaaac attaggagga attcattatg ttatacggaa aagataatca
     4021 agaagaaaaa aactatttgg aaccaatttt tggctctgca agtgaggatg ttgacttgcc
     4081 taaatataag ttaaacaaag aatccattga accacgaatt gcttatcaat tagtacaaga
     4141 cgagatgttg gatgaaggaa atgcgcgatt aaacttagct actttttgtc aaacgtatat
     4201 ggaacctgaa gcagtgaaat tgatgaccca aacgttagaa aaaaatgcaa ttgataaatc
     4261 agaataccca cgaacaacgg aaattgaaaa ccgctgtgta aatatgattg ctgatttatg
     4321 gcatgctcca aataatgaaa aattcatggg aacttcaacg atcggctctt cagaagcctg
     4381 catgctgggt ggtatggcca tgaaatttgc ttggcgtaaa cgtgctgaaa aattaggtct
     4441 tgatattcaa gcaaaaaaac ctaacctggt gatctcttct ggttaccaag tttgttggga
     4501 aaaattctgt gtatattggg atgtggaact gagagaagtc ccaatggatg aaaaacatat
     4561 gtcaattaat ctagatactg tcatggatta tgtggatgag tacacaattg gtattgtagg
     4621 tattatgggt attacttaca ctggtcgtta tgatgatatc aagggtctga atgatttagt
     4681 tgaagctcac aataaacaaa ctgactataa agtatacatt catgttgacg ctgcatcggg
     4741 tggcttttat gcaccattta ctgaacctga tctagtttgg gattttcaat tgaaaaatgt
     4801 tatctcaatt aattcttcag gtcacaaata tggtttggta tatccaggtg tgggttgggt
     4861 cttatggcgt gaccaacaat acttaccaga agaattagta tttaaagtta gttacttagg
     4921 tggagaaatg ccaactatgg ctatcaactt ctctcatagt gcagcacaac taattgggca
     4981 atactacaac tttgtacgct atggctttga tggttatcgt gatattcacc aaagaactca
     5041 tgatgttgct gtttatttag ccaaagagat cgaaaaaact ggtatttttg aaatcattaa
     5101 tgatggatca gaattgccag ttgtgtgcta taagctgaaa gaagatccca atcgcgaatg
     5161 gacactatat gatttatctg atcgtctgtt aatgaaggga tggcaagtcc cagcctaccc
     5221 attacctaaa gacttggatc aattaattat tcaacgctta gttgttcgag cagactttgg
     5281 aatgaacatg gctggtgatt atgtacaaga tatgaaccaa gcaattgaag agttgaataa
     5341 agctcatatt gtttatcata aaaaacagga tgtgaaaacg tacggcttta ctcactaaaa
     5401 ttcttcagag aaatataaaa gaagttaatt aactaataaa aggagttgtg attaccacac
     5461 agctccttaa atctatttga ataaatatat gatattcatt tgttacactc tcaatcttag
     5521 ctgttgttct attcatcatt actcttattg taagtagttc agtcaaattt gcttgttcaa
     5581 ttgatcgata acagtatgaa ttgtttgaaa agtaatcgga tatataattg ttttctcact
     5641 acctaagcct tcttggtata aagaactatc gcaaagtata atccgctgag tacaaaagaa
     5701 agtgtcgtct actatttctc taagttgttt acaaatgata ttactaatag aaaagtgttc
     5761 tcccaaaatg tcttctaact gttgtcgata gtataaatac ctaaagtctg acggagctac
     5821 tatgaacact tcaattggag atttccgttt atgctcattt aaaagactta aactaatggt
     5881 tagtttacga atagaattct cattccaacg cagaaataaa ttgttttgtt ttcgccattg
     5941 ttcaagaatt tcatgaactt ctaagtacaa agcgcgttgc tcttcattta acaagtaagt
     6001 cttatcaggt tgaaatatct gaatatcagc ccaaagtgag cggataaacg ggagaagtgc
     6061 tttatcaaaa agtatctgat tttcttcaga tatattcaga gataagataa gtttttgact
     6121 gagctcaatc accaaagggt tatctgctac atggttttga taaacaacgt tcaagtcttt
     6181 ttgtaacaat tcaaagttat cgcatagata atttctagag ttgaatagaa agtagatata
     6241 aaggcattca tcttcgtcat gacataaaga gaaagaaagt tgctctaatc ctttctgtat
     6301 tagctgaaac aagggagtat gtcgggcaac tcttttttct tcctgactaa aatatattgg
     6361 gttagtctta gatctctgca aaccgatagc gatacctaat aaaataaatt gtttttcaac
     6421 tgtagggtaa cttcttgaaa aaaatgtttt tctacataat caatcaattg ttgaccgctt
     6481 tgaataattg atttatttag ctggatcaac tctgtccgat ttgtctcata gattatcgtt
     6541 agtaacaaac ttcgataatc cttttcagga atttcaaaat ggccatcagc atttaagtac
     6601 tgcatttgtt taaaaaaatt aatcaactca tttcgtaagt tgtaaacttt gcttaacgaa
     6661 atgaaggtag tatcagctat attactccaa ttgtgttccc ctgataaata atgtcctagt
     6721 acattgaaaa agtcagagcg ctgatagatg agttgagtga gtgccaacct cgaaaacgaa
     6781 gagtcgaatg cgactgtaaa gctacttcta gatttctcca ctgaaataat ttgctgatgg
     6841 agtatgtcgg taatgcattc caagtcgtta gtgacagtga gtgggcaaac gttcaattga
     6901 tctgctattt cgcgaatctg aatggtccct ttttcgtgta attgctcaca aatgtaaact
     6961 tgacgaaaaa tacttttctc cagataggtt tccaacatag tactcctcct agtcatttta
     7021 tacataacta ttataactct accaatcgga atagtcctgt aatatattga atcaaaaata
     7081 taaattataa aataattaga tggggtattt ggtttaagta tcccttatat agtaataaat
     7141 ttataggtgt gattctcgaa ttaatacccg aaaatgtgag agaattttta tggatttttt
     7201 aggatacaaa ttaattattt ttgcttttat cctgattacc agtccagtac tgtcggtatc
     7261 ccattttgca gcaaaatcat gttgataaag tgacaagaag actgatgaga tatattatcc
     7321 aaattgagaa gataattaat cggattcttg agtataccct actttttaag aaagtagggt
     7381 atacaagcgt atgaataaag acataacttt ccctgtgatg gacgttcggc ttgttccaat
     7441 taccaaaata caggcgaacg attataatcc caatcgagta gcgtctccgg aaatgaactt
     7501 attggagctt tctatcattg aagatggctt tactcaacca ttagtttgtt attacaagga
     7561 aaaagaagag aagtatatct tggttgatgt gcttcatagg tatcgtgttg ctaaggaaag
     7621 actcaactta aaagttgtac cggtaacagt tattgataaa cccatagaag aacgtatggc
     7681 ttcaacaatt cgacacaatc gtgcaagagg gacccatgaa ataagaggaa tggaaattgt
     7741 catccaaaga ttagtaaaaa atggatggtc agacaagaga atatccaaag aattaggcat
     7801 ggacattgaa gaaatttttc gctttaagca agtgtctggt ggaatggcaa cagttttttt
     7861 gacaaatttt ataaggtgca gaacttcttt ccgtatgcta ttccgattgt ccttgacaat
     7921 gagcctcctc ggatgtgacg atcttcggca ggagctaaca gttaaagtta gactgcctcg
     7981 ctagcgttag cacatccgag ctcattatca aggattcgct gcgccaatct ctggttacgg
     8041 taaccaaccg gtgtctcgta gccaagtgta ccgtgcaacc gaaggtggtt ccaccaattt
     8101 acatagtcaa ataactccaa atccaattgt tgtaaggttt caaatgtgta ttgatagaca
     8161 aattctactt tcaacgactt ataagttgat tcagctacgg cattatcaaa aggacagcct
     8221 ttatgactca atgatcgatt gatgtcaaaa gttgttaata attcatcaat agcttggtta
     8281 tcaaactctt ttccacgatc agtatgaaaa atctcaacct ctgtcagagg ttgtttgata
     8341 cggctaaatg
//
LOCUS       DADVXV010000101         8088 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.104, whole genome shotgun sequence.
ACCESSION   DADVXV010000101 DADVXV010000000
VERSION     DADVXV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.104"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            173..874
                     /locus_tag="KB969_002495"
     CDS             173..874
                     /locus_tag="KB969_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6870416.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1483..2499)
                     /gene="tsaD"
                     /locus_tag="KB969_002496"
     CDS             complement(1483..2499)
                     /gene="tsaD"
                     /locus_tag="KB969_002496"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBB6870417.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2496..2960)
                     /gene="rimI"
                     /locus_tag="KB969_002497"
     CDS             complement(2496..2960)
                     /gene="rimI"
                     /locus_tag="KB969_002497"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6870418.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2967..3509)
                     /gene="rimI"
                     /locus_tag="KB969_002498"
     CDS             complement(2967..3509)
                     /gene="rimI"
                     /locus_tag="KB969_002498"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBB6870419.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3493..4215)
                     /gene="tsaB"
                     /locus_tag="KB969_002499"
     CDS             complement(3493..4215)
                     /gene="tsaB"
                     /locus_tag="KB969_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBB6870420.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4406..5386)
                     /locus_tag="KB969_002500"
     CDS             complement(4406..5386)
                     /locus_tag="KB969_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6870421.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5410..6894)
                     /gene="galT"
                     /locus_tag="KB969_002501"
     CDS             complement(5410..6894)
                     /gene="galT"
                     /locus_tag="KB969_002501"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBB6870422.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6906..7895)
                     /gene="galE"
                     /locus_tag="KB969_002502"
     CDS             complement(6906..7895)
                     /gene="galE"
                     /locus_tag="KB969_002502"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBB6870423.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         2295 a         1722 c         1417 g         2654 t
ORIGIN      
        1 aatcattcgc ttcaaaacaa attattcaat accattgtat attttttaca taataacaaa
       61 ttatatttgt aaagtattaa aacttgtttc taatgttggt atgttaaaac tttacaaatt
      121 ctttaaaaaa agtgacaata aatatagtga acaataagga gaggactttt taatgcgtgt
      181 taataaaatc gattttcact tttcaaaact cagatatcaa cctgattttg aacatttctc
      241 ggatgaagag ttccaacaga tcaaggaaca tactgttctt cgttcttata aaaaaggaca
      301 gatccttttc gacgatggtg atcccagaca acggttgtat atcttgacca aaggactcgt
      361 tcgtttagaa cgttatgatg aaagtgcaac ttattactac tatgactatg tgaatacaaa
      421 taaccttttt cctatgtcag gaatgtttgg agaagagacc tacacttata cagctcaagc
      481 gatgactgat attgaaacat tctaccttcc tgtttcctac tatgaaaaat tagcacgaaa
      541 aaatcccgaa cagttgatct atatgataca aaaaatttct aaagtagttg aaatacatga
      601 attgcgtatc caaatcggat tgacctctag cgcctttgac cgggtaaaac aaaatttatt
      661 cattttgaaa gaagaattgg gcgtaccaac aaaagatggt catatcacca ttccttatcc
      721 gatcacctta aaagaattag cagtgaatag cggcacgaca cgtgaaactg ctggacaagt
      781 aatcaaacaa ctacgtgatt ccgggctgtt agattatgac aaaaagcgtt ttactttctg
      841 taagacagct actactccag ctatgagaga ataacgcgaa caaaaataag cagtgaccct
      901 gataaatatc agggtcactg cttattttcc tccctaaaac ttctgaaaga tccggcagtt
      961 ttagatcact ggacaagact caaagatttt ctatgtgtgt ttcagttatg taatattcac
     1021 tgtttgcaaa aaatactgtt agattaacta gatgaagcgt cttgtcctca tccgatctag
     1081 attattcgat attcctcgac aataaacgat tactcagtga gggcaatcag aggaacggat
     1141 aatgataaat aagctgtaaa aaatagcaaa ataacaataa tgattaaaag tatgtaaaaa
     1201 atagggcttt gacaaaaacg tgtcacagcc ctatttcgat taaacggtgt gtacctgtca
     1261 actcttcggt cacaagtcat aatgttcata aacatgagga gctgtttttt gaaattgttc
     1321 cttgtgaatc agagttaaac gacaggctta cgaactcttg attaaacggc gttcaaaagc
     1381 ttgcatacgc ggtaataaga acagccaggt caaaaacatg agaagccgtt tttcctgggc
     1441 tgttcttatt acttgatgca gggcagcttt ttcacaacct ctttattcag ataaaaccaa
     1501 gcttggatca gcattcaact gatagctagc aaaatttctt ttttgcattt ccacatgtgc
     1561 tgctgctcca atcattgcag cattatctcc acaaagtcga agagggggaa tcactagttc
     1621 tacctcaggg agtttagctg ccaaagcatc ctgcaatcct tcacgcaacc cttgattggc
     1681 cgctacacct ccagctataa tcagttgctt gactggataa ttttgacaag ctcgaagtgt
     1741 tttagtaatc aatacatcga tcacacttgc ttgaaagcta gctgctaaat catttttgtc
     1801 tagatcttct ccacgctgtt gtgcattatg caccaaattg ataaatgcac tttttaatcc
     1861 gctaaaactg aaatcataat tatcttcatg gatcatcgct cgcggaaaat ggtaattatc
     1921 ttttccctga tgagctagct gatcgatttc ttttccgctt gggtaagaaa gacctaatac
     1981 tcttccaact ttgtcataag cttctcctgc tgcgtcatct cttgtctccc caatgatttc
     2041 atatgatcca tcttcttgca tatagactaa ttctgtatgt cctccgctaa caagaagtgc
     2101 catcaatgga aactggaatg gtttaaccag acgggctgca tagatatgcc ctgccatatg
     2161 gtttacagga ataagcggca attggtgtgc ccaagcaaaa gccttagctg cagaaatacc
     2221 aatcagcaac gagccgacaa gtcctggtcc ataagtgaca gcgactgccg ataaatcttc
     2281 tgccgacaca ccagcttcta ccagtgcatc ttccaagcat aaggtgattt gttctacgtg
     2341 atggcggcta gctacttcag gtactacgcc accaaaacgt ttatgactgt ttatttgaga
     2401 agcaacgatg ttagataaga tctctgttcc atttctaacg accgctacac tcgtttcatc
     2461 acaacttgat tcaatcgcca gaatcaattc ttcattcatt tcatcgtctc cgtttttaac
     2521 tttctgctca taatgatcgc atcttccgtc ggattgcgat aatatgattt ccgtttacct
     2581 aatatacgaa acttttctga ttcataaagt tttcttgctg cttcattaga tagacgtact
     2641 tctaaaaaaa catgcagcga atcttttatt tgttccgtaa tcagtaattg taacaaatgc
     2701 cgtgcatgcc cttttccttg ttctgaaact gcaacagcaa tatttgtgat ctcgacttca
     2761 tctattactt tcgagtatcc aataaagcca cagatctggt tatcttcagc taaaagcaga
     2821 taatcagagt gaggctgttg gatgtctgcc aaaaactgca ttttcgtcca aggtgaacca
     2881 tgtggataag cattttcgct aatcatccat acgcattctg ccaagtacgc ttcatcaaaa
     2941 tctttttttc tgcaaatcaa ctaatctcac tcattttcta aaagttttat catatccaac
     3001 gcatcttctt ttgtttcagt gtaatatctt tttttgatcg ttgttgcttg aaaccccaat
     3061 ttccgataaa gtctttgtgc atcttgatta ctcatacgca cttctaatga catcgtctca
     3121 cagcgattca ttatagcaaa gttctcgatt tcgtcaataa gcagcgaacc gattcgttta
     3181 cgctgatatg ccggtcgaac ggcaatattc gtgatatggc aatctaaacc gaacgctctt
     3241 gaaccgataa aaccaatcat tcttccatta tcaaagatac ctagatatag atgaggaagc
     3301 ggtgacttca attctgatat aaaggcactt tttgtccatg gcaattcgcc attatagact
     3361 tctcgttcga catccagcag ctctttgata tcttctgtag tcaattctct tagtacgtaa
     3421 cgacgatcga tttgttcgac tgttttttct gtataaatca ttttatcttg aaaaaagctt
     3481 ctggcatacg ctctaaattt tttcaacata actttcgtct ccaggtgtgt gcgtctccaa
     3541 ccatttttct tctgcttcta ctcgttttaa atagcgagga agaaaagctt gtttctctgc
     3601 aactggttca actaaagcac ctaattgagc cacagttaca ccacttggaa tatcccatgc
     3661 tggaactgta ttaatcatcg cactaggcaa tatttccttt atttcagaga agaatttgtg
     3721 acaatcactc ccgacgaaat aaatagcttc attcagcttt tgtagttgtg tgaacaaatc
     3781 agaagcagaa atatgtacat cttcaagtac agtttctaat ctattttctt tccagcggta
     3841 tgccccagcg tatacatttt ttcttcgagc atcaaacatg ggcacaataa tattatccac
     3901 accgatgcaa ttagccgcga tggttttcag actagatact cctactagct ctttatctaa
     3961 tgtataagca atcgtttttg ctgtcgttac acctatacga agccctgtat aagaaccggg
     4021 accatcagaa accgcgattc ggtcaatgtc ttttggactt atttgaagat ctgcaaacaa
     4081 ttggtcgatt gcaggcatca gtgttacact gtggttgcgt ttgatatttg tttgtatttg
     4141 tccaagaatt tgttcgtctt ctaccacacc gatcgccaaa gtttggtttg cagtatctat
     4201 tcctaatgta atcatatatt tgatcctttc tgctatgaca ttctcgcctt ccattgtagc
     4261 atactttttt attctgagga tgaaaatacc aaaggcaaaa ctagtacaat aatacatgat
     4321 tatctgctgg cgggcaaatt ttgccccttc ctgaaacaca aaaaagctgc ggtatcactc
     4381 cattttccca cagcttttcc atcttttatt tcgttgattc tcgaataatc aactctgttt
     4441 ccacaataat ctttcttgaa accggtgctt tggaattact taattgaaga atcgtctcca
     4501 ctgctagctc tcccatccat tcggtataaa cttttacagt agaaagcgag ggcgttacat
     4561 atttcgctac actgacatca ttgaagccca tcacagaaat atcttctggt accactaaac
     4621 ctttttcttg aatcgctttc agtgcgccaa tcgctaatgc atcattagct gcaaaaagcg
     4681 catcaggaac atgcggattc gtttttaaat attgcttcac tgcttgatat cctgactcga
     4741 cagaaaaatc tgcttcgata attggacctt cgtcgtagcc tttttctgcc aaaacttgtt
     4801 gaaatgccat aattctggga tcttttagcc gctgatggtt tttcttcgta tattctgttc
     4861 cagcaagcat agcgatatgt tgcgctttat gggagacaaa gtgttcaatg actttttgaa
     4921 cacttgactt aaagtcgaca actagagagt cgattccttg agaagtgccg tcagaatcta
     4981 ccaaaagcaa ggcattttgg gatcctttca tttctaataa ctgagcttcg tcgaattttc
     5041 ctagtgcgat cgttccatct gccggaagat cactaatgga atcccacgtt tctttcaata
     5101 aagtaacgtt tgcttcttct gccttttttt cgattcctag gcgaatagat aaataataaa
     5161 gatcttcaag ctcttccgta tcgtcgtacc actggatcag gcgaagcgtt tgcttagtat
     5221 ttgctgcatt tttacgatgt ttcgtataat ttaagcgttc tgctgcttca aaaatttttt
     5281 gctttgtggc taagccaacg gaaagatcag gatcatagtt gagaactctt gaaacagtag
     5341 caggagaaac tcctgccaac tgcgcaatgt ctttaattgt tgccatttgt ctctcctcct
     5401 tttttacgtt tataaaatcg cagtaaatcg ttcaaacgct gcctgtcctt tttcatctcg
     5461 cttgaatact ccagcgtctt ccagtacacg tgcaaaaacc tgacctacag atttttgtac
     5521 gacatcggtg accgtatctt tcgtcaaatc aggatgttct ttttttaatt gttctgccca
     5581 cggacgatga tattcagcca tctggttttc ttctcctaat aagaaatgct ctacttctac
     5641 tagttctggt ttcaaacgag gtggtaaaac agcaagcccc attacttcga tcaacccaat
     5701 gttctccttt ttgatatgtt ggacatcttt atgtggatga aaaatcccat caggatgttc
     5761 ttctgaaaca ttgttgtctc gaaggacaag gtccaactca aagtaattgt cccttcttcg
     5821 tgcaattggc gtaatcgtat ggtgtggtgt accatctgct gaaaaagctc tgatagatac
     5881 tgtttcatcc gaatatgctt tccatttttc caatactgag ttagctgctt caataagcaa
     5941 gtttttctct gttgattgca aacggatcac agacatcggc catttcacga ctcctgcgat
     6001 gacttgcgga taatcttcta gtttgataag tttttctatc ggtgcttttg ccataggaaa
     6061 ttcatgacgt cctgcctgat aatgatcatg agaaagaatc gatcctccaa caattggtaa
     6121 gtcagcattc gaaccaacaa agtaatgagg caagacttca gtaatccgaa gcagtctagc
     6181 aaatgtttcc tttgtgattt tcatcgggcg gtgttgttct gataaaatga tcgaatgttc
     6241 attgtaataa gcataagggg aatattggaa tccccagctt tcaccgtcta gattcattcg
     6301 aataatccgg tgattggtgc gggctggata gttcaagcga cctctatatc cttcgttttc
     6361 catgcaaagc atgcaggtag gatagtctac ttttaccgcc tcgcgttctg ctgcgatttg
     6421 ttttggatct ttttctggct tagataaatt gattgtgatt tccagttcac catactccga
     6481 ctctgccgga aatttgatgt tttttgcgat ggctcttgtt ttgatgtagt catttttctt
     6541 acttaaatta aagaaatact cagttgcttc ctctgggctt ttcgaatagt gctgtgcaaa
     6601 gaatgcattg acgactgaag gtggcggtgt gagaaaatcc attaattgcg cttcaaaaat
     6661 ctcttgttct gctggcaatt ctgaaagaac accattttct cttgccttag cgacaagctg
     6721 atccaataag tctacagatt cttccttaac tggtcttact tcaatgcttt ctagagcatc
     6781 ttctcctacc atccctaaaa gacgattctg taaatataag cggtccattt ccatccatcc
     6841 gccagcttcg atcgcaagtg tggcaaaatc acaaatcgtt tgactgattg acatatctca
     6901 ttcccctatt cttcataacc atttggatgg ctgacatgcc aatcccatgc tgttttgata
     6961 atcgctttga tatctgtgta ttcaggtttc cagcccagaa tctctctcgc tttttcactt
     7021 gaagcgacta atcggctagg atctccagct cttcttggtg ctatttctgc tggaatttct
     7081 tttcctgtca cttctctagc tgcttctagc atttccttga ctgagtatcc tttgctgctg
     7141 cctaaattga agaagttgct ttcatttcct tctttcaagt attccaaagc taaaatatgt
     7201 gcagcaatca aatcttctac ttgaacataa tctctgatac atgttccatc tggtgtatca
     7261 taatcgtctc cataaacagc caaggctttt ctttgaccaa gagctacttg taaaatgatt
     7321 gggacaagat gcgtttctgg tgtatgatct tctccgatag atgcatctgc ttttgctccg
     7381 gctacattga agtagcgcaa agcgacatag cgcatgccat atgcttggtc acaccacttc
     7441 atcatttttt ccatcatcaa tttactttca ccatacggat ttttaggatt agctggtgta
     7501 tcttctgtga ttggagactc tttcggctct ccataagttg ctgcagtaga agagaatacg
     7561 attttattca cgttgaactc gtgcatgact tcaagtaaga tttgcatacc gtatacgttg
     7621 ttgttgaaat acatcaatgg tttttcgaca gattctccta ctaaagagct tgcagcaaaa
     7681 tggattactc cttcaatcgg ttccttttca aatacggaac gtagaaattc tttatcccgg
     7741 atgtctcctt cataaaaatg agcatctgga tgtactgctt gtttgtgacc tgtgagcaaa
     7801 ttatctacca cagctacttg ataccccttt tgaactagct ggtctacagc gtgcgaaccg
     7861 atataaccgg ctccgcctag tactaaaatt gtcataaaaa acactccttt gattagtaaa
     7921 attgtgtttg ttgattctat ataatttaaa aaacgaagtt tacttttatg gtgaaaacaa
     7981 acaaagtaaa atttcgtaaa ttcatatggt aaatttataa taaaacattt agtaaacatt
     8041 ttcaagggtt ttttgcaaag gtttacaaac aaacgtaaaa ctagcctt
//
LOCUS       DADVXV010000102         8030 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.105, whole genome shotgun sequence.
ACCESSION   DADVXV010000102 DADVXV010000000
VERSION     DADVXV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.105"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            26..802
                     /locus_tag="KB969_002503"
     CDS             26..802
                     /locus_tag="KB969_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBB6870424.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            817..1020
                     /locus_tag="KB969_002504"
     CDS             817..1020
                     /locus_tag="KB969_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870425.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            1036..1374
                     /locus_tag="KB969_002505"
     CDS             1036..1374
                     /locus_tag="KB969_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBB6870426.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            1361..1540
                     /locus_tag="KB969_002506"
     CDS             1361..1540
                     /locus_tag="KB969_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870427.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(1583..2053)
                     /locus_tag="KB969_002507"
     CDS             complement(1583..2053)
                     /locus_tag="KB969_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870428.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            2140..2838
                     /locus_tag="KB969_002508"
     CDS             2140..2838
                     /locus_tag="KB969_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBB6870429.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            3016..3357
                     /locus_tag="KB969_002509"
     CDS             3016..3357
                     /locus_tag="KB969_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870430.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            3350..4021
                     /locus_tag="KB969_002510"
     CDS             3350..4021
                     /locus_tag="KB969_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBB6870431.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            4027..4719
                     /locus_tag="KB969_002511"
     CDS             4027..4719
                     /locus_tag="KB969_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870432.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            4716..5465
                     /locus_tag="KB969_002512"
     CDS             4716..5465
                     /locus_tag="KB969_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870433.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            5477..5746
                     /locus_tag="KB969_002513"
     CDS             5477..5746
                     /locus_tag="KB969_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870434.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            5752..5916
                     /locus_tag="KB969_002514"
     CDS             5752..5916
                     /locus_tag="KB969_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870435.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            5909..6208
                     /locus_tag="KB969_002515"
     CDS             5909..6208
                     /locus_tag="KB969_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870436.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            6208..6510
                     /locus_tag="KB969_002516"
     CDS             6208..6510
                     /locus_tag="KB969_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBB6870437.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            6550..6915
                     /locus_tag="KB969_002517"
     CDS             6550..6915
                     /locus_tag="KB969_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870438.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            7405..7545
                     /locus_tag="KB969_002518"
     CDS             7405..7545
                     /locus_tag="KB969_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870439.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            7542..7724
                     /locus_tag="KB969_002519"
     CDS             7542..7724
                     /locus_tag="KB969_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870440.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            7737..7931
                     /locus_tag="KB969_002520"
     CDS             7737..7931
                     /locus_tag="KB969_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870441.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
BASE COUNT         2973 a         1239 c         1670 g         2148 t
ORIGIN      
        1 aatataaaag aaaggaatga gaaatatgaa cacaccgcaa atttttaatt tcgaacaaaa
       61 cgaagttcgg acaattttag taaatgatga accatatttt gtaggcaaag acgttgcgag
      121 tgttttgggt tattcaaaca ctaaagatgc tttgtcgcgg catgtagatt tggaagataa
      181 gatggggtcg cgaatcacga cctcaggtca atcaagagag atgacaatca tcaacgaatc
      241 tggtttgtac agtttaatct taaaatcaaa acttccctct gccaaaaaat ttaaacgttg
      301 ggtaacaagt gaagtgttgc cagcaattag aaaacatgga ggttatctaa ctccagaaaa
      361 agtagaagaa gctttgctta atccagatac aatcattcaa ttagcaactc aactaaaaga
      421 agaaagaact ggaagattaa tcgcagaaca aaagattgca gagtacgaac ctaaaatctc
      481 ctatttagat agcatattat cttctacaga ttcagtaaca attagtcaga ttgcagcaga
      541 ttatgggatg tctccacaac agatgaataa attacttcat aaactaggta ttcagaaaaa
      601 agtcggtaac caatggttat tgtgcaaaaa acacatgaac caaggataca caaaatctca
      661 tacaactgag atcccgaaag ccgatggtgg cactaaaatt gtaatgaata ccaaatggac
      721 acagaaaggg cgtctattta tctacgaatt actaaaaaaa gaaggatatt accctcaaat
      781 ggatttagag gaaattggtt agaaaggagt tttagtatga ctgacattgc agaaatcact
      841 caacgagata gagaaaaaat caaagaatat gtcgaaagtt caaagttctt aacttacacc
      901 atgcttgctg aaagatttgg aattagcaaa agctacttat ctttaatttt aaacggtaaa
      961 aagacttctg cagaagcaaa cagaattata gattcgatta tcactatgta cgaattgtaa
     1021 agggaggaac agctaatgca atatctagaa gcaaaaatcc caattccaga aggctatgta
     1081 attatctccc aagtggatta tgaggagtta aaaaaagctg atgatactgg tagatggatg
     1141 acgttgccag aagtgctaga acggattaac agaaaatatg attggtttac ttctagagtt
     1201 ttaaagaacc caagatatag aaatattatc gatatcgaga aaaacaaaaa tggatttgtc
     1261 tattatccag ttgaaggaag agacacatat ctatttttaa gaagtaaaac acttgaattt
     1321 ttagaaacaa atttttcgga aatcttaagg aggcaagcgg atgggaaaat ttaatagagc
     1381 gctagtgttc agcgcaccgc taatcatcta cgctttagga ctttggggaa gcaggcaagc
     1441 gttgatagga acgattgttt acatggtttg gatttttatg gggcttgatg aagctgaagc
     1501 tgagtacaga gcgaaaaagc caaccgaggg ggctgactaa aaatgaatag aaaagagaaa
     1561 ctagaatgta tattactatt actcagttta attctttcac taatttctct attgggaagt
     1621 ttgtattttt gatatcaaca attttgtgga tttgggttct atttagagta aatatcattt
     1681 ttgtttggtg attaaggagt ttattaaaat taattttccc tacttcaaat gcaaggtaac
     1741 aagatatagc acttttagga ggaatattta gcggtacagc ttcagagtat attctattat
     1801 catcgactga tcctccttta gcaattaatt tcttaaatgg agtagctgac catctgcggt
     1861 ttaagttagc ggatgaaagt tctaaattaa ctaacatagc tggttctgtt gaatagttag
     1921 aaatgattac ttttgtataa atcatatctg cagcgaagta agaagcatta agttcaactt
     1981 ctagttgagg gcgcattcct tttattttta tccctgttaa aaacgtactc aatataaaac
     2041 ttattattga catccattga aaaattgtta agtgaaaaaa attcaaaata aacaccacca
     2101 gtttttaact aaattatacc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg
     2161 aaaaataaag aagctgtgac tacgagctta caagtggcag aaagcttcga gaaaaaacat
     2221 caacatgttt taagagatat tgatgcacta aaaaaagatg tgtccaattt tggacagatg
     2281 tttgtagaag gtaatgaacc agattcatat ggcagaaatc gacgagtttt cttcattagt
     2341 agagatggat ttttcttgct ggctatgggg tttacaggaa agaaagctat ctacttcaaa
     2401 caaaaataca ttgaagcatt caacgaaatg gaagatgtta ttcgcaagaa tactgttcct
     2461 caaacaattg aagatatgat gatctatcaa ttagaagaaa tgaaagatgt taaaaaagat
     2521 gtttccatgc ttaaagatac tatgcgaatt agcggacaac aagagtttga aattaagcaa
     2581 aaaggaaata tgaaagttat gggagttcta gggggaaaag aaagccgagc ttatgaagaa
     2641 atcagcaaaa aagtattctc aaaattttgg tctgaattta aacgtacctt ttcaatccca
     2701 agatatggcg agttacctcg taagagattc gatgatgctg tttcatttat tgaaatgtgg
     2761 ttgccagaaa ctgcgatccg tatggaaatt gatcaactga acagacaaca gagacttttt
     2821 ggtgatgaca atgaatagag ctgaagcgct aagaataggg acggcaattg ctaattgctg
     2881 gtggaaatac tataaaccaa tcatcctaag ccaacaacat attgacaagc aaaaagcatg
     2941 gcaacaaata aaaaagtgac tccgccggca agcaaagagt cacaaagaaa acacatcata
     3001 aggagatttt agcatatgga aaaagaactt tccactctag atcaatattt gattgatcct
     3061 gattggggca agccgaaaat tgaggaaaca agtggtcgaa aaatcagacg aaatcttttg
     3121 acgaatgaag aactagcttg ggatcaagat gatttaggca accatgtaac tatttgggat
     3181 catgtttatc ttatccatct atcgaagcat tcgaataaac ctgaatatat ttacgtcatc
     3241 gaagatggct tgattgatgc gctagaagag tacgacagag ataacttgat tgatatctct
     3301 tattacggac caggtaagaa atacattgct gaaatggagg cagaatttga tgagtgaaat
     3361 caaagggaca acgaactttg aaaaactttt tagtcgtaag ttaaataaaa ttctcaagaa
     3421 aaaaggaaat tttgattatt tatcttgggc tcacgcgtgg gagattatga aaaagaatga
     3481 tccacaggca acggtaacta ttaatgagta caaacactac agggttgttt ctggaactca
     3541 tcaagacttt cttgttgagg aatataaacc ttttcttatg gatgaaactg ggacttatgt
     3601 atctgtctca gtaacggtta aaggacacac ggaaaccgaa ttatttcctg ttttagatta
     3661 tcgaaaccaa ccagttgtta aaccaaatgc aatgcaaatc aataactcat tgaagcgatg
     3721 ctttgtgaaa gcattggctc tacacggact gggattatat gtatttcaag gggaagatat
     3781 tccaacacca cctagaatcg atacaaagaa attaaacatg ctagagacga ttctagaagc
     3841 tttcaatgag cagatgggta aagatatgac caaaacctta atcgaatatg ttaatgagca
     3901 gacagataaa ttagggctct tagctgataa cgttgaaact attgaacagt taagctatga
     3961 gcaatgtgcc ttgatggagc gagcaatagc agctaagaga aaagaattag ataagaagtg
     4021 atatgagtgt ttaaaccatt aatcgattca tattcagcgg ttctgaaaaa gttcaaagga
     4081 aaagacataa gcgcaaccat caatgaggaa gtgaacattg atcgactaaa gacgatgtat
     4141 gacggctacg atggtgatcg agtcattgaa attcgtttta ttgatcctag acgtttcacc
     4201 gtacagcaac gaaacttcat ctatgcgctg ataggcgata tttttatcga tacaggcatg
     4261 ccaacggact tctggaagga attcttctac tttcgttttg aaggtgtcac agggcgcaaa
     4321 ataagcctga aagacgaatc gaatacaact gtgagtgatg ccaatgtctt agcaaatatc
     4381 atcttagatt tcatctttga acatcatatt cctttcaaag aaggctatga gattttacct
     4441 gcgaatcaag aatattactt ctacaaatgc atcacaaaaa gagtctgctg catctgtggc
     4501 aaaacaggag ctgacatcga tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa
     4561 gttgatcatg cagagtacac atttgcagca ctctgcagaa tccatcacac agagaagcac
     4621 aaaataggtg tgattaattt caaaaataaa tatcaaatca aagggatcaa attaaaccag
     4681 aaaacaatca aaaagttaaa tattggaggg gaaaaatgac agaacatcga agttattatg
     4741 cgattatacc agccaacgta aggtacgaca aaagacttaa accaaatact aagttgttat
     4801 acggagagat aacggccttg tgtaatgaaa gaggcttttg ttgggcaggc aatgagtact
     4861 ttgcagattt atatggtgtg aataaagaga ccatatcgcg atgggtaagt gatttgatta
     4921 agtttggata cttgaatcgg gaaatcattt acaaagaggg taccaatcaa ataatcaata
     4981 ggtacctacg aattaatcaa taccctattg acgaaaaacg caatacccct attgacgaaa
     5041 aagtcaaaga taataataca tctattaata atacatttaa taatacaaaa gaatatataa
     5101 gagagttacc gccttcgaaa aaatcgaagg ctaagcccgt ccgtcataaa tacggagagt
     5161 ataaaaatgt tcttttgtca gatgagcaga tggagaaact caaaacagaa ttccctaatg
     5221 attaccaaga gcgaatcgaa cgactgtcag agtattgtga atcatctggt aagacttata
     5281 aaaactattt ggcaactatt cgaagttggg caaggaaaga aaaaagtgaa cctaagaacg
     5341 caagcagtgg atacaagcgc acaggaagac gagagaagct tcctgaatgg gcaatcgacc
     5401 aagaagccta tctcaagaaa aaagcgctag aacgagctaa tagacaatca aaagcaccat
     5461 tctaagaggt ggaaaaatga agatcgatta tctagaacta attaatgaaa tagcgaatta
     5521 taaaaagggc gaggaattag acgtcctgag agacgtatat gatcaactcg aagaagctgg
     5581 aattgaagga attaagaatg atcgttcgag ttggagtaaa ctcagatact atttcgcact
     5641 ctatatcgat ggaacgcaat taagaaattt agcatatacc aaattactat tcattgattg
     5701 tgttaaaggc ttgcaaaaac atcttaatga acttgagcag gtgtaaacaa gatggaccta
     5761 aagacattta cagcacagat cgaattaatg catcaagaag ctttaagaca aagtgtgtcg
     5821 tacgaagaca agtggctcaa cacatttcat ggcggacgtg agagcgcact tgatcaagta
     5881 ctcaaattac tgaaaggaga atgtcgggat ggataagaaa gcggcaatgc agcgaattat
     5941 cgaattgact tattcagaag attggcagga agataaaaaa atagttgcag aagtccaaaa
     6001 gctcggtaaa tcaatgtgga ctgaaaagcc caaacggaga acgccgagaa agattgcaat
     6061 ctggcatggt gatcgaattc tagtaacggg taccgctaaa cagttatctg aaattactgg
     6121 tctgagcaaa aatattattt gggatagagc taggagctta tggattgatt caaaaggaag
     6181 acagtttagg tatgtggagg agaaataatg gacgaactaa tcgcgaaagt agagcagtgg
     6241 gcaaaagata agggattgga tcaagcggat ttcagcaagc aaatgttaaa aacggtcgaa
     6301 gaaatcgggg aagttgccgc ttctctagct agaaaagatg aacatggttt aagagacgga
     6361 attggcgatg tagtagtaac cttgatcatc ttggcaatgc aaaatgatat ggatttatac
     6421 gagtgcttgg attttgctta tgacgaaatc aaaggtcgga ctggaaagat ggtcaatggt
     6481 gttttcgtta agtccagtga cctgaaataa ttccattaat ggaagaaata actgaatagg
     6541 aggatagaca tgattgatgc aaaacaagtg caaaaacaga aagatggaat gttgatgttt
     6601 gaagcatatg ttctaccatt tcttaatcaa tttgaagttt tggaatgctc tgccagcgga
     6661 gaagaattgg agtatgttgt aattcgtgaa accaaagaaa acgttcagaa gctaaacgaa
     6721 tttctttgca ctattaactg ttgggatatg atagctccag gatttttatg tccagctatg
     6781 ggagaatttt tggaatattg tcgtcttgaa gatgcaggca ctttggattt agcttatctg
     6841 gtatacaact acctaaacat caacacagat catttgtggt ttggcactgc cgaaagaaaa
     6901 tgggtagtcc gctaaccacc aatatcaatg aaaaaaggcg gtttcctgaa agtggaattg
     6961 ccgccattgc tgtaaggttc tttacgcgac tcaaggtcac agaaatataa atgcaaatct
     7021 cttttgaagt gatccaaagc tctcggaaaa tggaagtttt ttgtttcaaa gaataaatga
     7081 gatttgcgtc aagaacctga gagttatttc caaaaaagct tccaaagaac cgaatgagct
     7141 aaggacatca tgtgtaaaca cataatatag ctctcctttc acggctaatc ataacatgaa
     7201 aaatattcga tgtcagtagg aaaaaaggtg aattatgaaa agaatattaa attatcccgg
     7261 cagtaacaga ttctgcaatt aaactccgaa gctgatgtat cagtatcaac tgtagaatat
     7321 tatgagcgtg gagaaagtca agcagtcaca aatgtaaaaa tcgataacgt caacggtctt
     7381 atctgtttag atgaaggcga tagtatgaat gaaattgctg cagaccatga attatcagaa
     7441 actgctttaa ttgatcaaat cgaattagct agacaatact ttgttccata tgcagatacc
     7501 tggtccaagc ataagaatga catcattttt ccagaggaac aatgagagca actgatccag
     7561 taattatcct tgaggaagcc aaatttattt ggactcacga agagatagag caagcacgct
     7621 tgctcttttc tcaaggagtt aagccgagca aagtagctga aataatgggt caaaagattc
     7681 ttgatgtcgg attgcttttg ctccatctag cagaaaaaat ttgatttgag gtgaaaatga
     7741 tgattcaact tgcaggcatc caaacaggga aaatttattt ttctggagaa agcaaaagcg
     7801 aagccaacca atggctattg aaaacttaca cgaacaataa gaagctaagg aaaaaatatc
     7861 ctgatttgtt gctaaaggat gatcagatta tgccggaacc gatgattttg acccgtaagg
     7921 agggaagttg aaactaaaaa accagccgtg tgggctggag ttgctatttc tttttaataa
     7981 tgagtttttc taaatttaat tcattctcac gagtttgcgt ccaataatca
//
LOCUS       DADVXV010000103         7731 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.106, whole genome shotgun sequence.
ACCESSION   DADVXV010000103 DADVXV010000000
VERSION     DADVXV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.106"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            578..1183
                     /locus_tag="KB969_002521"
     CDS             578..1183
                     /locus_tag="KB969_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBB6870442.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1199..1771
                     /locus_tag="KB969_002522"
     CDS             1199..1771
                     /locus_tag="KB969_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6870443.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2023..2280)
                     /locus_tag="KB969_002523"
     CDS             complement(2023..2280)
                     /locus_tag="KB969_002523"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870444.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2406..3221)
                     /locus_tag="KB969_002524"
     CDS             complement(2406..3221)
                     /locus_tag="KB969_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870445.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            3738..5063
                     /locus_tag="KB969_002525"
     CDS             3738..5063
                     /locus_tag="KB969_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBB6870446.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5056..5406
                     /locus_tag="KB969_002526"
     CDS             5056..5406
                     /locus_tag="KB969_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870447.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5403..5573
                     /locus_tag="KB969_002527"
     CDS             5403..5573
                     /locus_tag="KB969_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870448.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
     gene            complement(6477..6752)
                     /locus_tag="KB969_002528"
     CDS             complement(6477..6752)
                     /locus_tag="KB969_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBB6870449.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(6724..7677)
                     /locus_tag="KB969_002529"
     CDS             complement(6724..7677)
                     /locus_tag="KB969_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6870450.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
BASE COUNT         2610 a         1229 c         1371 g         2521 t
ORIGIN      
        1 tatttattag gaatggctct tgcttatagt gttggttctt tgataaaggt aaacgtgtca
       61 cttgatctat ttactatttt actagcggtt ggggtatctt cggttattgg actggtcttt
      121 tctgtaatgc ccgcttcaga ggctgcaaaa aaagatttaa ttgatattct tagataaaat
      181 cagaatgaca agaatattta cgttctagat tctaaaataa aacacaaaga gaccaaccag
      241 gcaccctatt gtttctttgt agtatagaga tattctttgg cttgtaagag atcaatagag
      301 ttaggtgacc ggagttcgaa ataaaggaaa tttttgattg tataggagaa ttctttatcc
      361 ctaatattta gaattttgag tatgccatgt tgatgtttta gattctctat aaatatagag
      421 gtgtatcaaa ggtcaactag actgtgcaaa atagagacac ttgaaaaatc tatcgggggt
      481 cagaaactta atagtttttg acacataaac aaaatcgcga tataatgggg ttgagagtgt
      541 ttcataaact tatgtcataa agttaaggag atttcgcatg attttagaga ataaattggg
      601 attaaccaat caagttgagt tggctaaggt tgaagaaaaa ctcagtaaac aaaaagcgaa
      661 agaattgtac gattgtggaa aaataaatga aatcgaagtt ggtacattta aaggtttatc
      721 tgaaattcat gaatttctat tttcggatat ttacgatttt gccggaaaaa tccgatcggt
      781 caatattgca aaaggaaatt ttcgatttgc accagttatg tatttagaac attcgttaca
      841 gcatattgat cagatgccac aaacttcttt tgaagagatt atcaagaaat atgtggagat
      901 gaatatcgct cacccatttc gagaaggaaa tggccgaagt actagaattt ggctggatct
      961 cattttaaag gaagaattgc aaaaagttgt agattggaac ttaatcgata aagcagacta
     1021 tctttctgca atggagcgaa gtcccataaa cgatttggaa atacgctatc taatttccaa
     1081 tgctctgact gataaaattg acgatcgcga gttatatatg aaaggaatcg atgtcagcta
     1141 tttctatgaa gggtattctg agtatacgat agatgatttg taaaagtagg tggaccaaat
     1201 gacgaaatat ggatatgcac gtgtctcaac cgcttctcaa agtacaaaag aacaaattca
     1261 acagttgctt gagaacggcg tagagaagaa gaatattttt tcagaaaaat ttacgggtac
     1321 aaaacgggat cggccaaaat tcaatcagct gttggctggt ctgaagcctg gagatgaaat
     1381 agttgttacg aagcttgatc gatttgctcg taacacgaga gaagcattag agatcattga
     1441 acctttactc gatgataacg taacgatcaa ggttttgaat ctaggaacga ttgaaaatac
     1501 gtccatgggg cgaatggtga cacggacgtt gttgagtgta gcagaaatgg aacgtgatat
     1561 gattgtggaa cgtacccaag aaggaaaaat gtttgcaaga aagaataatc ctaatttcag
     1621 agaaggacgt ccgaaagcaa caatcacacc gaagaagagg cacgcatatg aactgcttac
     1681 ttcaggtaaa tcgtataagg aagttgaagc tataaccggt ttcagtcgca gtacgctttt
     1741 tagaataaag aagaaaattg aagaaagtta aaaaagaagt ctcagcgaac cagacaggta
     1801 aatacttaat gcgttctaga tatgagtcta ttagcatgtt gtgaaatata atattttttt
     1861 atttacttga tttctgctca aaaaatgtgt atggtaactg taaaaggtaa agtaattaaa
     1921 ggtatgctag ccacgcttac tatattagga taccatcata tatttataat gaacgatttg
     1981 ttcgtctacc aaacaacaca tatcgttcag cgtaagtcac gtttaggaac gtggcttttt
     2041 tagtgttatt atcgataaat aatctattga ctctattgat tttatctcca tatccctacg
     2101 gtgttgattg tctttagatc tttcatttaa gaaccaaata actatcataa aaatcagcac
     2161 tgctgctaat ataataaaca gcattcctat tgtgatatta cctattgatt ttaccataac
     2221 tacgattaaa gtaataatgg cattcaagtc tcctttgttc tctatatata aattagccat
     2281 aaatcatctt cctttcaaat taagatactt gtttgatacc aataaatagt aagcgtggct
     2341 agcatacctt tttctgtaat agcaagtgtt ctaatagtcc aaacttaatg atggaccgat
     2401 gctagttata gtacagtaat gttttctttc ttatctagat ttttagtaag ctctatcagc
     2461 aaatctaaca aatctgagtc cttttcagaa actaaattaa atctagtgtt tacaacaaag
     2521 ttttcatgtt ctatattgtt tagattattt gcggaaagga gggcttctag atcttgacat
     2581 tcaaatctat atgcatcgtc ataaatctta ctagaaggag tgcttaattc gaaattactt
     2641 attttctcat cttggaccaa gataaattta tagatagtat ctttttgtgt ttttctttta
     2701 aaaacacaac agagtgtgtt ataaggaacg ttataatttt catcagcctc attttttctc
     2761 cattcaaaca aatgataaac tgcaaccaag ttgccatcaa tttcatggac agtgctctcg
     2821 gtaacatcct ttaaagaact atcaagggct aatttatagt aactagagag aggaagtaaa
     2881 attgtcgatt tactgagatg gttatcgtct atacgtgcaa tcatacctaa atcaactaag
     2941 gttttattcc aggtgtttat agttttagtt gtcactccta gagactctgc tatggtattg
     3001 accgaatgcc aggaatcccc gccttcattc tttgccttaa aacagtaata cagatataaa
     3061 ttaatagctt tgttattcgg taaatatttt tcaagttctg ttggtagaat aaagtaagaa
     3121 tccttaatgt tttttctgaa ctgtctccag tctctgtagt tttgtttata aagttgtgaa
     3181 acggtttttc cacctttaga aagtcctgct atcttaacca atcttattgc tcctttcttg
     3241 aatctgtcat gatcatacag tattttttac ttgtagtcca gcaccttaat atattatcct
     3301 atgtaattaa tttcgtacta gatagtaatt attttttatt taattctcta gtcacttaca
     3361 aataagttat ataaactacg attaataaat tattacaaaa actattaaga aaacttctac
     3421 atacaactat tacaaaacta ttaagaaact gaatactcct attttttgtt tttaaggaaa
     3481 gttttttctt ttttgaattt cttatttttt tctaatataa ctaagcaaaa ctggataata
     3541 cgacacttat tttcaaattt tcacaagact aatagtaaat atccatttaa taaagtgata
     3601 caatgtgttg attttacaaa tcaacagaag aagtagggaa ataacttacc tatgcttctt
     3661 tttttgtaca tttaatcgat tcttctttac aaaaacgaac gtatgtttgt ataatgtgga
     3721 agaatggagt gttatttatg atggattatt caaaagagcc agtaaatgat tactttttga
     3781 tcgatatgaa aagcttttac gcaagtgtcg aatgtataga aaggaattta gatccattaa
     3841 cgactgaatt agtcgtcatg agtcgagcgg ataatacagg atcagggttg attttagctt
     3901 cttcaccagc tgcaaagaag aagtacggta tttctaatgt cagtcgacca cgagatctac
     3961 cgcaaccttt tcctaaaacg ttacatgtcg ttccaccacg catgaatctc tatattaagc
     4021 gaaatatgca ggtaaacaat attttcagaa ggtatgtagc agacgaagat ttattgattt
     4081 actcgatcga tgaatcgatc ttaaaagtga ccagatcaat gaatcttttt acgactgaag
     4141 gaacaagaag tcaacggaga aagaagctgg ctcaaatgat ccaggagaat attaaagaag
     4201 agctaggatt gcttgctaca gtaggtgtcg gagataatcc cttattagct aaacttgctt
     4261 tagacaatga agcaaaacat aatgatggat tccttgctga atggacgtat caaaatgttc
     4321 ctgataaagt atggaatatt cctgaaatga cagacctttg gggtattgga tctcgaatga
     4381 aaaaaagact caaccaaatt ggtatcatga gtattaaaga cttagctaat tggaatccat
     4441 acactattaa gagccattta ggtgtgattg gcttacagct gtattttcat gcgaacggga
     4501 tcgatcgaac agatatagcg atcccaccag aaccgacaaa ggaaaaatca tatggtaatt
     4561 cacaagtgtt accacgagat tataccagga gaaatgaaat cgaactggtg gtaaaagaaa
     4621 tggcggaaca agtagctatt cgtatcaggc aacataactg taaaacaggt tgtgtccatt
     4681 tatacattgg cacgtcgatc ttagaaacga gaccaggttt ttcacaccag atgaagatcc
     4741 ctataacaga taatacaaag gaattgcaga attactgtct tttcttgttt gataagtatt
     4801 atgaaggaca agaagtaagg cacgttggaa taacctatag caagcttgtg tacactgatt
     4861 cgcttcagct ggatttattt agtgatccac aaaagcaaat tgacgaagaa aatttagata
     4921 aaattattga caagattcgg caaaaatatg gttttacgtc gattgtacat gcttcttcta
     4981 tgttagaagg cgctcgtagt attactagaa gtacattggt tggtggccat gcaggcggcg
     5041 caggagggct taaaaatgat tgattataat gatcgtggac gtttaaagtg ggcaggtttt
     5101 tatttatctg atcatactga aaaaattgat gccgacaatg aacaacgagc caatcaaaat
     5161 ttggcaaaag aacaaatgac gactgaagag gttgcggaag tattgaacgc tgcagtcata
     5221 aaaaatagat cagtatgtat tcaaaaagaa gaacgaaacg ctgaaggata ctatccagaa
     5281 gatattgtta gcaagatctt aggtagtgat gagctgggga tctacgttgg aaaaaacaaa
     5341 gttcactacg acgaaatacg tcatatcgaa ttttaccagg ataataaatg gggtcgatta
     5401 gaatgaacat tatccagcaa tatgagctaa agtatataac ctttgatcag ctatcagaag
     5461 agatttgggg ttatggccag cgtttgataa atgaggttgg tgttgaacgc ttctctttct
     5521 atgtagaagc tgcagcagga taccataaat acgaatacta tattggctat taaagtgcaa
     5581 taaaattata tttcttttat gttttacatt ttgtatcaat tctgataaaa ttacctatag
     5641 gtaattaaaa aatataaaaa aactagttac aaccttagga cgttgtaact agcttgaagc
     5701 atactagagc taactaaaat agcactagaa agcaatgtta aacccgtcca acaaacttga
     5761 tttaacattg agaccagctt attcagctaa atatagttga ataagcttct tttgttttaa
     5821 aaaaacaaaa ggtgtactac gaataacgca agtaaaagaa atactattac aaccagtagg
     5881 ctacaagtaa gtattactaa acattgcgta gttagaacct ttgctctatt gtctaaagcc
     5941 acaaaattag agatcagctt tatgatgcta agagcgagct gcatccatgc ggacataggt
     6001 tcttttgaca ctattaattc tcctttttag gataagggaa attgctagta gttttttcat
     6061 tagcaccatc ccccttcatt tgattgagtc tagtgctgct gtgatagttt gctgtttaat
     6121 atgcttacat tcttattata acataaatga aacaaacaca tggttagagg tcgtatcaat
     6181 caaaatagtg tctcacaaac gatttattac ttactcctgc tgactaacgg actgttcttc
     6241 agtaactgta actatatgtt tgttaaaacc accattacct gtagataaaa accaatatat
     6301 ttactatact cactatatta aatatattta gtatagtaaa aactagaaac aataaaattt
     6361 gtgaatgttg tataccccca aacaatacac atattttgaa ggattaggat taataaagct
     6421 aaaaatatag taagtatact aaatatattt actatatcta gtatacttac tatattttaa
     6481 tcttttgatc gtctattata tataatccgt tcctcgtcgt ttaaagtatc aacataggcg
     6541 tccattgcaa gtttgactat ttcatacata ggaatatctt ttgcataact aagatcccga
     6601 atggttttta gtacgggagg atctacttga actggttttc tttctttcgc agtgtacttt
     6661 cgttccccta actcgacatt aatatcatct ttaattgaaa tatcttcagc accaattttc
     6721 ttcttatctt tgttcgttgg taataatgcc atttagttta atctcctttc caagaggtag
     6781 gatatgattg gccattgagt cagcatattt aggtgtataa tcaaatcctt caatatcacc
     6841 atgttgttca tagtattcaa ttctttcttc taattctgta aagatgtctg caaaaatagc
     6901 ccaccatctt cgatctacat aatcatttaa ttggatacca ttctcaccat acatttctaa
     6961 ccgatccgag cctttaacaa tgcttttaaa aatgtttgat tcaccatact tatcaattgt
     7021 tttttgatag tttgcgtgtt gagaggaacg tcgcactgag aaaagaacag gcaaaattcc
     7081 aatgatttga agatgagact cttcaaaatt cgtgacaatc ggaactaaaa ctttattaat
     7141 aaaatcttct gttccttcca ttgcgtaccg ttttaattct tgcattgcaa taatataatc
     7201 tgcagcagtt aagaatgcac gaaccacatt atctgttgat ggtgggcagt cgataaagat
     7261 ataatcgaaa ttttttctca attcttctaa aggtttaatg aaggccaatg atctcttacg
     7321 acgatcagga tatttttcgg acaagtattc attaagttct tcagatccag gagagccagc
     7381 cataatatat aaatgtggac ttacttgagt aatacctgaa acccagtccc cttttttgat
     7441 tgctgcagac atggatcgat caaagctagt aatttgatac gttgatccaa tgttggaagt
     7501 agtatttctt tgttggtcat aatcaattag caacacgtct ttttcaaaaa gttgactaga
     7561 aacaatcgct aataaatcat tgtctgtagt cttaccaatg ccgccttttc tacctgtaag
     7621 cattacaact tttcctagtt tatctgatgt tttaaatgca gtccgtaagt tttccatagt
     7681 tccctccaat ttcctatact aaatatattt agtatacttc atatacttaa t
//
LOCUS       DADVXV010000104         7704 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.107, whole genome shotgun sequence.
ACCESSION   DADVXV010000104 DADVXV010000000
VERSION     DADVXV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.107"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            17..2344
                     /locus_tag="KB969_002530"
     CDS             17..2344
                     /locus_tag="KB969_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBB6870451.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2470..2799
                     /locus_tag="KB969_002531"
     CDS             2470..2799
                     /locus_tag="KB969_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBB6870452.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            2839..3843
                     /locus_tag="KB969_002532"
     CDS             2839..3843
                     /locus_tag="KB969_002532"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBB6870453.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3840..4286
                     /locus_tag="KB969_002533"
     CDS             3840..4286
                     /locus_tag="KB969_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBB6870454.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            4436..5251
                     /locus_tag="KB969_002534"
     CDS             4436..5251
                     /locus_tag="KB969_002534"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBB6870455.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5457..6629
                     /locus_tag="KB969_002535"
     CDS             5457..6629
                     /locus_tag="KB969_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBB6870456.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6839..7324)
                     /locus_tag="KB969_002536"
     CDS             complement(6839..7324)
                     /locus_tag="KB969_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870457.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQEAI
                     AQQQAEQARQQSAAEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATL
                     S"
     gene            complement(7321..7515)
                     /locus_tag="KB969_002537"
     CDS             complement(7321..7515)
                     /locus_tag="KB969_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870458.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
BASE COUNT         2579 a         1457 c         1538 g         2130 t
ORIGIN      
        1 tttattgaga ggagggatga aaatgattaa gaaaactcaa aataaaatcc aacgtatatg
       61 tcaaaaacat tttgtttcta gactcaaagc tgtatctaaa agaaaatact tacatcccat
      121 tatgatttcg atcatcttga tttttacttt cttagggagc ttatcaagta tttatgtaaa
      181 cgtttataca gaaacgtcaa attttgctaa ccaaacgaca gaggagacaa atagtccacc
      241 ctattctgaa atacagtcca tagaaagcac caatcagtct agcaacaacg agacaacctc
      301 aaccacatcc tcgactcaac tgattgatcc gacagaaaaa gaaatcacag cagcaaaagc
      361 agcaggggag aaagcttatt cagaaacagg tagaagccag acatttagta ctgttgcggc
      421 cactgcgaat ttcaacggac ataccatacc agatggatat acagtgatat atgccaaaga
      481 tggagtcatt gttgcggtta acggatcgat gagtgcggat aaaactgcgt tacaaggcgt
      541 aaccaaagca atcgctttta ttgataaccg tccagatatc cataatctgt ttattggctc
      601 cacagtaaat ggtactacta tcacattccc aaaaagtatc tatatggggg tggctaccgc
      661 tggaaatacg atcgattcag ttacacccaa tgcggataaa agttattctt ttacaccctc
      721 aacatgggga gggcttcctg ccggaggagg tatgagtact ttttcaatcg gtatacagtt
      781 agcaaatgat attccattca cggggtactc gatcaaaaat gggcagatcg ttgatggtaa
      841 gggaaatgtt tcaaattttc caacctatca agcagcaacg gttcaggtca atgcgaatcg
      901 gacaggaact ttttcttata cagtcaatgg tggagcagca aaaatcggaa cgtacgggac
      961 tacattatct ggaatccatg tgggtgacaa agtggttatc actccaacag cagtaacggg
     1021 ctattctttt gcacaaacaa acggttcttt cacagcccta gaaagtaacg tcgatacggt
     1081 gacctataca ggcaaacaaa caccaatcac tattaagtat caagactatt ttggacagat
     1141 gattgctcct tctaaaataa tgaatcttac ttacggaagt gctgcacaag acctgacgac
     1201 taatacgcct actatcaacg gatatacctt tacagctgtt tcagcgatag aaacaaagaa
     1261 ccaatcagca atgagtgttt tagctagttt agatacaaat ggaaatgtaa tcgtaaagga
     1321 cgcaaatgga aaacagattt ctgaagtcat cctatattat aagacaaatg caacagtatc
     1381 aatcaatgca aatggcagta agtactatga tggtctttct gttgtaccga tcgttaaata
     1441 tgcctttaat gataaaacag aatcaacatc ccttttaaac aatgatctca gtattgatca
     1501 aatcacatgg aatccaactg atttcaaagc gatgaatgaa aagggagttg aagtaactgc
     1561 gcctactgaa attggaacct atacgtcttg gcaattgaca aaaagcggac tagctaaact
     1621 agctgccaga acaaactatt tatttactat cgtgcagaca tctgatgtct atacgattaa
     1681 gcaaatcagc ggtgcggtag agctcagtgg cagtaagaca tatgatggaa aagcaggtgt
     1741 cccgtcaatc catgtcaagc tagcagaggg tgtcactagt tcgcttactc cagtacaagt
     1801 ggcacttagc agtatggatt acacagcaga tgcacaatca gcaaaaaata tggttaatgc
     1861 tggcagctat acaattaaac taacgaatag cggaatagac aaagtcaaag cagcaaatcc
     1921 caagttgtca tttactgata tagccaacac atcaggaact tataccatct ataaagctaa
     1981 cgcagtgatt actgtcgatg acgctgcctt taattatgat gcccaaagtc actcgatttc
     2041 ggttggaaat ctccacgtta ccggtgttgt cttaggcgaa tcattggatt ataccctaac
     2101 agttaacagc cggacagata ttggatcaca aatagtaacg attagtttag gcgaaggaag
     2161 tgtaaacaat aattatacga ttatcgcaac agataccgct aagttgacga tcaatccgac
     2221 tctcttgctt ccttcgacag gtgggatagg tctactgccc tttgtctttt taggactgat
     2281 ctttattttt tctggcttct tttattttat ccatcgtaag aaaaaagcag gtgaacagcg
     2341 atgaaaaaaa caaaaaatgt acgtgtggat atatttgctg ttctcttttt tatcctactg
     2401 gtctttttta taggttctcc gactgtgtca gctagagaat cacctattac atttactttg
     2461 cataatcgaa tgttcgaaag cgataagatg ccaagtatca gtcaaaacga cggaataaat
     2521 atcccggata actttcaagg agtaaaaggg ttgaacggcg ttactttcgc tatatatgat
     2581 gtctcggatg aattttacaa gctgcggtca gaaggaagta gtgtggaaga cgcacaaaga
     2641 aaactagcac aaaaaagtga tagtgaaaaa atactggcag aaaatgtgac aaaaacagta
     2701 gacgaggaag agggcattgc ttcttttagt gcatcggaca aagatgagca aggtcgtgac
     2761 gctgtttacc gatttacgga aataaagact tcagattaag taaaagaaaa atcagcacca
     2821 tttgtcgttg tgcttcctgt gacagattca tctaatcata aattgacgac catccacttg
     2881 tatccaaaga gcgaacaaaa aatacctgct gcactcacat taacaaaaac agtagagaat
     2941 aagcagacag attttgcaga tggggataaa gtcccttatc tcatcaccgt aacaattcct
     3001 gagaacatca acgagatagg aacctatacg atcaaagata cagctgatcc tcagttatgg
     3061 ctagaaccag aaacgatcga ttttttgatt ggtggagaca agattcatac atttcacaca
     3121 caaaaaataa aacatggttt tgtcttatca gattctggaa aagatcttag ttcgtttgct
     3181 ggaaaaaaat taacgatccg ttaccaaatg acattgaaag aaaacagtga aaaaacgaca
     3241 tttgataacg atgtacgttt gacgactgac aatcaaacag tagaaacaca tcttgccatc
     3301 caaacaggag gcaaacaatt tgtcaaagtg gatcggcaaa cgaaacaaaa actagcagat
     3361 gctcaatttc tagtcaaaaa aaatgaccaa tacttagcgc aagaaaacgg gataaatcat
     3421 tgggtagcca aagatgattc aagagcaacg atttttactt ccagtaaaga tggaacattt
     3481 tctgtccatg gattgtcttt tggaagttac gaactagtgg agattaaacc gcctaaagga
     3541 tatatattga gtcaatcaac cattctcttt gaagttgaaa aaggcagtta tgatccgctt
     3601 catcctatac cattggaaat catcaacgaa ccaaaagcaa atccgacgaa taatggaaaa
     3661 acgccagttc agatgcagac aaatggtcca tcaaatgaaa aaaatggagg aagctttcca
     3721 aaaacaagcg aagagatgct tggaggtttc tcaattttag ggttattgct agtcctttca
     3781 acagggacag cttggtttta taaaaaacaa caaaaaggaa acaataggag ggaaataaaa
     3841 tgaaaaacat caaaacaaaa atatggacgt ttttaggaac tgctatcatg ctgcttcctt
     3901 tcgttctcgg cctaggaact gcagaggttt ctgcagccgt atcacctaca ccagaaaatg
     3961 ttacggttaa tttgcataaa ttgaaattca cttcagcacc agaaaatcaa ataaacaacg
     4021 gaacggaatt gacatttccg aatagcgaac cgttgaacgg cgttgaattc aacgtatatg
     4081 acatcactgc tacgtactat ccaagtaaag acacagcagt tccagcagac gctacaccct
     4141 tcgcaagtgt aacgacttct ggtgaaggat tagctaacct gactcttcca ggtaaatctg
     4201 atgggaaaga tgctgtatac gtctttgtag aaacaccaaa gcccggtgtc gaaacgtcgc
     4261 caaatatcgt gttaagctta ccctagaccc tgacaaacct ttagacacga ttcacctata
     4321 tgctaaaaat gtcatcaaag aaagcaatat caaaatccag aaagctggga acttttcagg
     4381 ggtagataag ttagcagggg cgcaattcca gatcaaaaat tcagagaatc aattcgtgac
     4441 cggttttgat gaaaacactg gtgtcgctct ctatgatcct gctgagtcag cgttgacatt
     4501 cacaactgat actgaaggat ccatcagtgt caatggatta atagacggca attatacttt
     4561 agttgaaaca aaagcaccag atggttatca attaaccaat ccacaaaaag aaactacttt
     4621 tatagtaaaa aacggaaaat tgcaacaaac aaccggtatc atccatggcg cagatgaagc
     4681 caatcttggg aatccaaacg gtgtagtcaa tcgggaaaat acaactacgg ataacacgat
     4741 tactgtagaa aatgtccaaa actacggtga tttccacttc atcaaacaag atgtgaacac
     4801 gcaagaaaaa ttagccgatg cagaattttc tattctaaga gcaaaagatc caactgttaa
     4861 attaatgaaa aaaatagcaa accttgcctc aggagaatac ccatatgctt ggtcagatga
     4921 agtcacaggt tctgactggg aagaagtgaa attgatttct gattcagaag ggaaattttc
     4981 aatcgaaggg ctgaaacaag gggcatactg ccttcaagaa acaaaagcac cagaaggcta
     5041 cgcattacct aagaatgaag ctgcgtacac tgaatttaca gtagatgatg atccaacaac
     5101 ttctgatgaa acaacgatcg ataaccaacc taaaggaatc ttgccttcaa ctggtggtat
     5161 ggggatcatc gtattcatct tggtaggtac tgctttagtt ggaggagcag tgatctattt
     5221 caaaaaacgc catcaagaaa cagaagctta aactattgga aacaaaaatc atacgataaa
     5281 taaacgatag tgattcaaat ggggagaaag gttgtgacaa gtggtcggtc tcttggtatt
     5341 cgctcaacaa acggcaaaat aggaggaact attttgccgt ttgcttcgct aatactcagg
     5401 tcaaggcgct gatttcacaa cctcttcata tacatattag aaaataggtg gacatgatga
     5461 ataaaagcag aataagaata ctggacatct tcatggcaat cattttagtc gttgggatcg
     5521 ggatcttttc ttatcctttt gtagaagatt cactgaatga ttttcttgcc cagcaaatga
     5581 tcatccatta tcaaaagcaa gcatcgaata agaattcaga ggaaataaaa aaacagcagg
     5641 aaaaaatgac aaagaaaaac caacagttgg cagagcaaaa cgtatcacca gggataggca
     5701 gtttcaacca agcagttgat gcaaaagcat taaaagattt acctagtaat gcctttttta
     5761 tggaacatat gcttggagtc atcgaaatcc caaaaatcaa tgtcagctta cctatattcg
     5821 atcagacaac ggaaatattt ttgcaaaaag gaacgtcatt attggaagaa agttcttatc
     5881 cgactggcgg gaaaaacacc catgccgttc tttctgggca tcgtggactc ccagaagcaa
     5941 aattatttac agatttgcct aagttgaaaa aaggagacca gtttttcatc cagatcaatg
     6001 gaaagacatt ggcgtatcaa gtagaaaaaa tccaagtggt cttacctgat gaagtagatt
     6061 ctttgggtat ccaaaaaggc agagatctcg tgactttgct tacctgtact ccttatatgg
     6121 tcaatacaca tcgactgctt gtgacggggc atcgtattcc ttatcaagca aaagaggcaa
     6181 aaaaagcgat ccaaggaatt gatcaatgga aaaaatggaa attttttatt tggtttatcg
     6241 gtatactact tggatcaatc ggcttagttt ggctactcat cgcttattta gattctttgg
     6301 ccatcgctaa gcgaaactat cctttatctt tttatgtaaa gaacacaaac ggacgaccaa
     6361 tcgaaggaat ggtcttttct gtaaaaacgc tcaacggcaa acactatatt actagagaaa
     6421 aagttccatt tgtgaaagct tctgatgaat acggactagt gagattttct gatttaaaag
     6481 gcaggaacta tcgcttgcaa catgaggagc tcctgcttaa aatccatgta aaacataaac
     6541 attcgaaaca gttttcaatg aaattgaaaa aaggaagata taaactgcga aaagaaaaag
     6601 aggtgtacta tttgattgag aaagaatgaa tgaagatgtc caaaaaagca gagggaacag
     6661 actaaatgaa aaaagagaga agctgacgaa atggacgtgt aaactgttat ttttggttta
     6721 ctatctggaa cgccatcttc tattttttta tgtttcagaa gaattttatt attatagtat
     6781 aacttttgaa ttagtttcca taacatttgg agcaaggggt taaaccacga gcttgagctt
     6841 agcttaaagt ggcaggggta tacgtaccat ttccacattt atgtgtatgg tattttgaac
     6901 cggtcggtgt gacatagaca gtttgttcat tattttgctc aggagctgcg gcttgtgcct
     6961 gctgagaggc ctgttcagct gctgattgct gtcgcgcctg ttctgcttgt tgctgtgcga
     7021 ttgcttcttg cctcgcctgt tctgcttgtt gctgtgcgat tgcttcttgc ctcgcctgtt
     7081 ctgcttgttg ctgtgcgatt gcttcttgtt gcgcttgttc tgcttgttgt cgtgcaattt
     7141 cttcttgctt tttccgttct tcttctgctt cttttgcttt gattgtggaa tcaattgcag
     7201 caagacggct tgtcaactct tgtttgtttt caggtagcgc ttggatagct gctgaagcag
     7261 ttgcatagtt ttcttttgta ggatttgctt cagcttgtga caaagcagat tccgcttctg
     7321 tcactttttt tctagtgcag ctttttccgc tttttgtttc tcttcttttt tcttttcaat
     7381 ttgttcttgt tctttcgatg aatctgccgt actttcggag atcgtggtac tgctgctgga
     7441 agcctgatct gaacttgtgc tttgagtagt agacgtagta gcaccacacc cactcaacaa
     7501 acttcctgcg accaaaaaca atgcaactaa ttttttcgct aaatttcctc cttaagtaaa
     7561 aaacaaccgt tttcaataaa tgtccttttc aattgtttac ttacttgtta taataattgt
     7621 gttatgaata gtgattgagg aaacttaatc taatcccgtg ttgatacacg ggattttttg
     7681 ctatagttct gttattaagt atgc
//
LOCUS       DADVXV010000105         7634 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.108, whole genome shotgun sequence.
ACCESSION   DADVXV010000105 DADVXV010000000
VERSION     DADVXV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.108"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(241..966)
                     /locus_tag="KB969_002538"
     CDS             complement(241..966)
                     /locus_tag="KB969_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870459.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1120..1446)
                     /locus_tag="KB969_002539"
     CDS             complement(1120..1446)
                     /locus_tag="KB969_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870460.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(1483..1848)
                     /locus_tag="KB969_002540"
     CDS             complement(1483..1848)
                     /locus_tag="KB969_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBB6870461.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(1885..2100)
                     /locus_tag="KB969_002541"
     CDS             complement(1885..2100)
                     /locus_tag="KB969_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870462.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            2229..2564
                     /locus_tag="KB969_002542"
     CDS             2229..2564
                     /locus_tag="KB969_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870463.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(2640..4637)
                     /locus_tag="KB969_002543"
     CDS             complement(2640..4637)
                     /locus_tag="KB969_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870464.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(4735..5010)
                     /locus_tag="KB969_002544"
     CDS             complement(4735..5010)
                     /locus_tag="KB969_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870465.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            5242..5976
                     /locus_tag="KB969_002545"
     CDS             5242..5976
                     /locus_tag="KB969_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870466.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            6015..7157
                     /locus_tag="KB969_002546"
     CDS             6015..7157
                     /locus_tag="KB969_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6870467.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         2581 a         1388 c         1095 g         2570 t
ORIGIN      
        1 aaatatacaa atttcttaaa aattttttca ctaaaatcac tacctgaaac agtctaaaac
       61 acttatatat caacgtttaa tgaaactatc tccgtttcat ttcagataca aataaatata
      121 gtcgggctcc aaatccgaaa aaaaataccc ccagtagctt atcctaagct actggagatg
      181 tataagtacg gtcatataac aacggggtag ggtaaataaa tgaaaaagat ggaagaatca
      241 ttattcaata acttttttaa atacttcgtt gtaatcagtt acctgtccgt tcttaaatac
      301 cacagaataa tcttttttcc cattttcaag taaccgaagt ggaatatctt taccaacttt
      361 ctctgtcact gcattactga tacctgttag attagctaat aaatctgata aagattgagc
      421 atctgtagaa atctctgtat cagtatttat cgtgattcct ttatcttcat ttacaagttt
      481 ccaagtaggt ggtatagctg tgtatgtttc tacaaatgaa ttaagttttt cattaagtga
      541 cttctctttt atatttccat ctaaaaactc tgtatatatg gcttgagcta tactaaaaca
      601 aagctggcct tgttctaata attttacatc attagttagt aaagctgtgt tcacgttatc
      661 aatcgcttca agaagagtat ctttggtgtc cctaacagct ttaggtgtgc cttctggaat
      721 ttccctactt gatacctcgt ccattttatc ttccataaac cccttaaaat catatctttc
      781 tcccaaatcc atagaagttt ttgagaaagc tttcatttct gagtctattt cttcaataat
      841 atttaacatg tctgatacat attgtttagg ctgattcgtt tttaatctat atgtggtaaa
      901 tatctcaatt cctccaatta tcaataaaat tgccaaacaa atccataata attttttctt
      961 tttcattttt cctcctatac actgctgtta taacagtgac taatgtaaag attttcccag
     1021 caatcatcag actattattt acagggaatc aaaaaaactc cttagtaagc ttacaccttt
     1081 aggagttcct gtttgaacgg tatgcataat acatttaaat caatttaaca ttaacacctc
     1141 agtatatggt atctctacat atacacggtc tttttttgga tagtactcga catttatatt
     1201 gatagcactt ccattgtcta acgtagcttt agcccggtac gtgttatcac cattatcatg
     1261 agtgatcgtc acatcatcac atgtccgatt taagttatac tgttcttgta aaatctgagt
     1321 taccaatggt acagatgact tctctagtcc agatgaaccc gtcattcttg aaaaaattat
     1381 acctataata gccaatacaa cgatacctat aatgacaaac ttcttattca tatttacttt
     1441 attcaacttt ttatctccta tctccaaaat gattttctct catcagtaac tcattgacat
     1501 ccccaatagt acaccaaaga tggctccagc tacccctgct atcatcaaaa tcgtacccat
     1561 ttgttcatct ttctctcgat ataagtaacc cataataaca gcaacagcac caaataccac
     1621 aggaataaat gctaatgata ctaccataga aatccaacca ataatcaaat acagcttccc
     1681 tgtctcttgt ccatgtacga tttgttcctt catttcatta attgtctgct cagtactttt
     1741 ctttactgtg tctgttccgg ttgtctcatc tgtttcttgt aatgctccgc aaaactggca
     1801 atacttactt tcatttgtta tttctttacc acattttcta caatacatgt cttctcctcc
     1861 taaaatcatt caattgctta ttagctaact gtttacttta ttaaatacat cagaaaacag
     1921 ctcatttatt ggtacactta atatctcaga aagcattttc atttgatagg gtttaggaat
     1981 cgttctccct gtttgccacg aacttacaca ttgctgtgta acattcattt ttttggctaa
     2041 ctcagtttgg gaaagtcctt tttcttttct gtatcggctg agattactta cttttttcat
     2101 gattctcccc tcctgtttta ttatatacaa caatatgatg tatttcaact cataaaatat
     2161 ataaatactt caaatgtcat tacaaataca acaacttgtt gtactctact gagaaggggg
     2221 gtgtattaat gaaacagaag caatatgcaa aggtcattag agaaaagcga aaagcactcg
     2281 ggtggacaca aaaagaatta gctaaaaaaa tcttctctac acaacaggca gtagcaagat
     2341 gggaaaattc tgtaacagaa cctaacctcg atagcttaac agctctttct agagccctag
     2401 gaacccctgt aagccatttt ctagacaatg ttgacataga ttatgaggaa gagtttttgg
     2461 ctctctatcg ctctcttagt actgaagatg caattcgaac aattgactat atgaagctat
     2521 taaaaaggca agaaaatgaa cgcaatcagc tattgaaaga ttgaaaaata aataacccac
     2581 cgaactttaa cggtgggtgt attgagatga aataagatta agagctatgg ataacctgtc
     2641 tagtttaata taattgggtc tcttctattc cttactctcc gtccatcatc tcttgttaca
     2701 cttgtaaatt gataaatagg aactaattca actcctgata atatcaattc ttttattact
     2761 tcatctatcc ctgccccttt cgctagatat actaaaaaac tactgcttgc tttcacattg
     2821 tatagtttct taatatcctt agaagctcgt tcaagagtga atccttgttt aacaaagtag
     2881 cctctgtttt ctattaaagc atttttcacg ctgttatccc tgacatttcg taggcgttca
     2941 caaacagtgt taataagttc tttttctgtc attagatatg tcccttgcca cgataagccc
     3001 tgtaaaactt catgtgcttc atctaaaatc aattgttttt ccttgctaag ttctgatcgg
     3061 gaattttgag gaaatactct tttagcctct ttttcgttaa aacatatctt aacccattca
     3121 taagaaaaat attgatatgt aaaatgaaat ttttccagaa gtggaaggat atcttcattc
     3181 aatttttgaa tcacagaagt tgcattaaaa acgtctaatc gatagacatt gcttctctta
     3241 tgtttaaagt ttcctaacgc tttctcttcc tttaacctat ttaggtattc gagcatcttc
     3301 aaaggaacat cttcatcatc taattttttt atcaatccta taaaagtcat aagtgatagt
     3361 aacttattac atttatctat gtcataagtt ttaccatagt aagaactcat ttttttagct
     3421 aattgttccc ccgacaaaat acaagtcaca ctttccttac tatcatcaaa aaaattaaca
     3481 tcagaaagca agacatcata gacacgtcgc atttcctcta gataattcct tattgtcctg
     3541 aaaagtttgt ctttcattga ttcaagagtg tcaaaaagta cttttgattc ctctttcaat
     3601 tttcgaaaat gtgtaggata caagtctagg ttctctaata gccaattaaa tgtttctacc
     3661 cgactgtctt tctttaaaat tagcatcaca actccaataa aattttcact gatatcacaa
     3721 ttactggaat gacaataaaa aatggaatgc ccagttttac tggtaaaaat actagcagag
     3781 ggattatgat cgttgtgaaa cagacatctt aagtttttac ttgacttaag taatttattc
     3841 atatcaatgg ttaacaatct ttcataaatc tcattaaaag acatgtcgga ggaatcaaac
     3901 aggcagtctt taaaccactg tttcatttct tctttgtcgt cattttttat caacttaaca
     3961 aaatcggttt cattgactag ttcatactct ctccctgaat cactttgaca atttttagaa
     4021 catgtcatgg taaaatcaat cggaagctca gtaatatcta acatgttgtc ttcattaatt
     4081 attatcactg catctgactt atatcctcca aaaaacattc tattcgaagc atttacattg
     4141 tcatcacacc cggggatgtt ctttttcaag tattcgtaaa cagcaaccat tttaccatag
     4201 tcagtaattg cttcttttaa tagaaagaca atcttgtatt tttctagatt ttcagagtac
     4261 cgaatacttt tttgtatcgc aaacgcagaa ttatgaacta aattgataga taaaaccttt
     4321 tctatgctta agtatctact atcatcttta ctcaaatcta ctaccttccc cttctcatct
     4381 ttaacagtgt tatcgacatc cagaataatt actctggttt ccacaaaact ctccttgtca
     4441 ttgcctttat tctttgtctt gcttggaata aatgattgtg atgaatttag tatctctaca
     4501 aactcatctc ttgtaacttc tctatagtta tctaaacacc tatctcttac atcagttttt
     4561 tctttttttg taactggctt ctctaataat ttttctttat ctacataaat tggaatatta
     4621 atcattgatg tttccatttg tgtttcctcc ttataaaatt ctgttaaaga ctaaaacata
     4681 cagataataa aaacaaactc tttattacta tatgttttag tcttatttgt ttactcaacc
     4741 tttataccgt tccatgaaac tatcaatatc agatttttta aatctaatga ccgtatcaat
     4801 ttttataaca ggtaacccgt attgagaaac atattttcta atcgttccta ctgatacacc
     4861 tagatattca cttgcctgct gatagtccat atactctaga gtgactccag aaataatgtc
     4921 ttctagcata ggctttagca ctgtaattat ctctttcact tgttgttcaa cttgtataga
     4981 aacaatgcta tcaatgattt gtagagacat atttccccct cctttcgtga ttgcttgaac
     5041 aaattttcta agaattatct tcgtattttt tgctcaaaat aaaagtattt tgttattaac
     5101 cgattaatca aacaaaaaat gattaccagt tcatcgacat acacataata cctcgataaa
     5161 aaaggggtgt caatagtttt gtaaaattta tttacaacac cccttttttg aggtatacta
     5221 attttaggag gtgtggtcaa tatgataaaa cgtccaccaa taaattattt agaacgaaaa
     5281 aagatactcg gaacaaaaat aaaagctata agaaagagta aaaaattaac acaaccagca
     5341 tttggtctta tgattaacaa cggtcaatta attgacaaaa agactatcta cgaatgggag
     5401 aagggaacct atttaccaat accagagcga ttatcccgaa ttgctgattt gggaaatatg
     5461 agtatagagg agttagtttg tggcaatgta gaagaatata ttttgggaat tattctttat
     5521 agagatagca ttgtactaga tggtataaca tttccagata aaaacctgtt ccagcatctt
     5581 cgtcaacagt tcccaccagt acactctaat ttagatacat ggctggatag atattccaaa
     5641 ttagaaccag agatgcaaga atttattgct aacaagactt gtaataaagt taaaaatgaa
     5701 aaaattagtc ttttcaatat cttaaaaata gaagaattat tcatcaatgc tattgtagaa
     5761 gaatttgaca ataacattct tttcctcact agcagtatag aagaactact agaaagaatg
     5821 gtagatgaat ggctacctat tcaattgaaa gacatgtctt atcccgaaga agctgtgaga
     5881 gaaattactg ataatataaa caagctagaa caaacgattt catcaattgg gaaaaaatac
     5941 actaagaaaa aaatgaaggg aggtgatacc atctagtggt aagtactcct tgtaaactaa
     6001 gaggagatga tttcatggca aaaatatcaa agtacaaaaa gaaaaacggt caagtggcgt
     6061 ggatgtataa aggacacatt gccaccgatc cacgaactgg tgaaaaaata aatactacga
     6121 gaagaggttt tagtagcaaa caagaagctc aaaaagatta tgacgagtac agacatcaaa
     6181 tattatacgg tgttaaaaag aaagcacctg atatgacatt tgaagacctg tataatgaat
     6241 ggataactca tcagcgtacc agtgttaaag cttcaacaat cgcaatctca gtaagatacg
     6301 caaataatca aatacttcca gcatttggta agcttaaact atcgaatatc tctgtcccat
     6361 attgtcaaaa agtggtagat gaatggcaca gtaaatatga aagttacgat tatatgagaa
     6421 aacagactgc acaaatttta cgctacgggg ttgcaatgca atatattgac aataatccta
     6481 tggaaaaaac acttcttcca cgaaaaaaag agtatgagaa aaatcgtaaa ttttactcaa
     6541 aagaggagct taataattta ctggatgctt ttaaagattt tggtaacatg aaacaatacg
     6601 ccttcttcag attattggca tacacaggta tgagaaagag tgaagtactc gctttacagt
     6661 ggaaagacat agacacgttt aataaagaac tacatgtcaa taaaactctt gctgtagatg
     6721 aatttggtaa agttataatt caatctccga aaacaagagc ttctagacga gttatctctt
     6781 tagatactga gactctttct atcctcaaca actggaaatt acagcaaaaa gaagagtatt
     6841 taaaacttgg atacaatact agctctaaag agcaacatgt ttttacaaca gttaaaaaca
     6901 ctctatacat tccaaacact gttaatgatt ggttaagata tattttgaaa aaatataact
     6961 tgcctcgtat tacacctcat gggtttagac atacacatgc tagtttatta ttagaagcag
     7021 gagaatctgt caaggtagtt caacaacgat tagggcatga aaatagtaaa gtgacattag
     7081 acatctatgc acatattaca aataatgcac ctaagaaaac aggtcaagac tttgctgata
     7141 tgatggctca tcagtaaaag agctggtcaa aatctggtca tttctagtat acaggcaaaa
     7201 caaaaaagct agaaccctta tatatcaagg gttctagctc ctataacagg tttacccaac
     7261 actgccttcc aatgactctt ttgggaatca gaggaaagaa tcaggcttta tagagatatt
     7321 tcatctaaca aattacttta gactgacagt atatatcagc aggtactgtc atcgggaacg
     7381 tagccaatat cgtatccaaa acagcaggta gagaagctat ttgaggattc aagttattct
     7441 atttcaacca tgaagttaag ttcattaaaa ataaagatag ttggtatttc aataattttt
     7501 gtatagagtt aatcacttta ttgatgctaa ttcatcttga ttggtattat aatcgtattc
     7561 aagttgcgtg gcgtgctttt gctagaaaat atataactgt tctttataaa gaaatataag
     7621 gattaaacat tttt
//
LOCUS       DADVXV010000106         7603 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.109, whole genome shotgun sequence.
ACCESSION   DADVXV010000106 DADVXV010000000
VERSION     DADVXV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.109"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            67..2676
                     /gene="clpB"
                     /locus_tag="KB969_002547"
     CDS             67..2676
                     /gene="clpB"
                     /locus_tag="KB969_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBB6870468.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(2827..3513)
                     /locus_tag="KB969_002548"
     CDS             complement(2827..3513)
                     /locus_tag="KB969_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870469.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(3491..3985)
                     /locus_tag="KB969_002549"
     CDS             complement(3491..3985)
                     /locus_tag="KB969_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBB6870470.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(4005..5225)
                     /locus_tag="KB969_002550"
     CDS             complement(4005..5225)
                     /locus_tag="KB969_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6870471.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            5372..7207
                     /gene="lepA"
                     /locus_tag="KB969_002551"
     CDS             5372..7207
                     /gene="lepA"
                     /locus_tag="KB969_002551"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBB6870472.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            7403..>7603
                     /locus_tag="KB969_002552"
     CDS             7403..>7603
                     /locus_tag="KB969_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870473.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEE"
BASE COUNT         2529 a         1426 c         1545 g         2103 t
ORIGIN      
        1 tataatagtt tttgtaaaga tcaaagaaat aagtgatctt acctttaatt aggagggtat
       61 acctgtatga atattgagaa aatgactacg acgcttcaag aagcgattgc tgaagctcaa
      121 cagattgcgg tcactcgaaa acatcaagat atcgacattg cccatgtatg gaaaatcttt
      181 ttacaatcta atcattttgg tcgaaatttc tatacggatg ccggattgga tgtcgaatct
      241 tttgaacatg aaattgatcg tctactggat gagtatccag ttgtttctgg tggaaacgtc
      301 caatatggac aaaacctcag ccagaatttc tttcgattat tgaatgaagc agaccaaata
      361 cgtgaaagct tcggcgacga gtttctttca acggaagtcg ttattttagc gttgatgaaa
      421 ttaaaaaatt atccgttaac tgtttatttg aataaaaacg gattatctga aaaagaattg
      481 cgtaaaaaca tcgaagagat gagaggagga gaaagagtga cctcacaaaa ccaagaagaa
      541 caatacaaag cattagaaaa atacggcgtt gatttagtac agcaagtcaa aagcggaaaa
      601 atggatccaa tcatcggtcg tgatgaagaa atccgtgatg tcatccgtat tctttcacga
      661 aaaacaaaaa ataatcctgt tctgatagga gaacccggtg tagggaaaac ggcaatcgtt
      721 gaagggcttg ctcaacgtat cgtacgcaaa gatgtgcctg aaaatttaaa agataaaacg
      781 attttttcat tagatatggg tgcattgatc gctggagcaa aattccgtgg tgaatttgaa
      841 gaaagactaa aagcagtctt gaaagaagtc aaaaaaagtg atggacgtat cctcttgttc
      901 atcgatgaaa tccacaatat cgtaggggca ggaaaaacag aaggaagtat ggatgccgga
      961 aatctgttga aaccaatgct tgctcgcggt gaattacatt tgatcggtgc cacaacttta
     1021 gatgagtacc gtcaatatat ggaaaaagac aaagcgttgg aacgtcgctt tcaaaaggta
     1081 ttagtcaaag aaccaacagt ggaagatacg atcagtattc tgcgtggatt aaaagaacgt
     1141 tttgagatcc accatggtgt taacatccat gacaacgcat tagtagcagc agctacttta
     1201 tctgaccgtt atattactga tcggttctta ccggacaaag caatcgattt gatcgatgaa
     1261 gccagtgcaa cgattcgggt agaaatgaac tctatgccaa cggaattaga tcaagttact
     1321 agacgtttga tgcagttgga aatcgaagaa gctgcactga aaaaagaatc agatgatgca
     1381 agtaaaaaac gcttgaaaaa tttgcaagaa gaattagctg aacttcgtga agaagcaaat
     1441 gcgatgaaga tgcagtggga aacagaaaaa gaagaagtca attctgtttc agcaaaacgt
     1501 gctgaaatcg ataaagcaaa acacgaatta gaagatgcag aaaataacta tgatttagaa
     1561 cgcgctgctg tattgcgtca tggtacgata cctcaattag aaaaagaatt gaaggaatta
     1621 gaagctaaag caaaagacag cgagattaag atggttcaag agtccgttac cgaaaatgag
     1681 attgctcaag tcgttggcag attaacgggt atccccgtaa cgaaacttgt agaaggtgaa
     1741 cgagaaaaac taattaaatt gaatgaaaca cttcataaac gagtgattgg tcaagatgaa
     1801 gcagttgatg cggtcagtga cgcggtaatt cgttcacggg ctggattgca agacccaaat
     1861 cgtcctctag gttctttcct tttcctagga ccaactggtg tcggaaaaac cgaattagcg
     1921 aaagcgttag ctgagaactt gtttgactca gaagatcata tggtacggat cgatatgagt
     1981 gaatatatgg aaaaacatgc tgtgtctcgt ctagtcggag ctcctccagg ctatgtaggt
     2041 tacgaagaag gtggtcaatt aacggaagct gtcagacgaa atccttatac aatcgtcttg
     2101 ttggatgaaa tcgaaaaagc gcatcccgat gtcttcaata tcttgttaca agtcctagat
     2161 gacggacgct tgactgattc aaaagggcga gtagtagatt tcaaaaatac ggttctgatc
     2221 atgaccagca atatcggttc acagttactg ctggaaggcg tgactgctga tggaacgatt
     2281 ccagaagcag tggctgaaca agtcaacacg ctattacgtg gaaacttcaa accagaattc
     2341 ttgaaccgaa tcgacgacac gattttattt acaccattga gcctagacaa cgtgaaagga
     2401 atcgttgaca aaatggtggc gcaattggca caacgtctgg aacatcaaga aatcctgctg
     2461 acaatcagtg atgaagccaa aacgtggatt gctgaaaatg cttatgaacc agcatatggt
     2521 gcaagaccat tgaaacgatt tatcactaag gaagtagaaa caccactagc taaagaaatc
     2581 gttgcaggac atgttatgcc taaatcaaaa gtaacgatta ctttacttga tggacaactt
     2641 catttcaaaa cagaagagct agaagaaatc gtctaatctt ccattgagac tataaaagaa
     2701 aaaaggggtc tgacacaact agtgtcagac ctcctttttt caaataaaca gtgttccaga
     2761 agtagtttct tcgaaaaata agccgaaatt tcttgaagct gcccgcttct gtcacaacct
     2821 cttttattag gtatttttca ctttttctaa tttataactt tcaaagtaac gctcatcttt
     2881 tttactttga gaccatgcaa acaatcccat taaggcagca cctatcgtat ttgtcagcaa
     2941 gtcgcccatc gtatccatca atgctgctcg tccgacaaac agtgtgccat cagaagcagc
     3001 aaaacgttga agattcatgc ctaagaactg gtcgcataag aattcccaga actcccaaaa
     3061 cacgccgcaa agtccagcaa acgcaaagcc gaataagagg aacaaccaag gactggtttt
     3121 tgatatctca gcatctttca tcaagtaacc aatcaatcca tagccaagag ctgtcaggac
     3181 cattggactc accgcatgta agattttgtc ccaaaaagag atgatactga tcaaatgcat
     3241 ccctgtgcct aaaaagacag agatgaacaa gaaaaaccag taaaacaaaa cgattgctgc
     3301 tggtatttta agtttgaaaa ctttcaaaat gacttgtggc atgaaaatca atgcaatccc
     3361 taataaagat tccacgataa atgtgattcc ttgagaagtc gaatattttt gtgtgataaa
     3421 ttcataaaaa ttatagcaga caacgaatac accaaaagca agtaaagcta tttgcacctt
     3481 tttgatttct ttaatcactg aaagtccctc catctaaaaa tctttttact tctgaaagca
     3541 actcaatttc tgaagaaacc acttttccgt tcaatttgat caaacctatt gtatataagt
     3601 tcaggtagtg aaattgattt tcagctgttt cttgtagtgc agcgattttt ttcgggtggg
     3661 ttccgccttg ctgtcgagta tcagtatata agccgatcac tgggatgcct ttcgcataag
     3721 ccacaccgat ttccgatgct accccggcat cgatcgtcag cccatctagt aaagcaatca
     3781 ttaaatcact agccaacact ttttctgtgt cagcaagagc aatcattcga ctgtctgcat
     3841 aagcagtttt gtcattgatt gcttcatttt cttgaggaag atagatcgaa agctcagaag
     3901 agagctctct gatttcttta actaactgtt ggttatataa caaatcactt ttagcaaaca
     3961 ttggtgcggc aaaataaatt ttcatctaaa catcatcctt tttatcaaaa ataatcgcta
     4021 aagtaagctt ccatgtttgg aatgatacgc tctagtgact tcagtgtttc ttcatctgtt
     4081 tctaaccgtt cgattcttgc caaataagaa gcacggcgat aattcatcat caagcaagtc
     4141 aatgtttgga tatccagtcg aacggatttt cctataggtt catttaagac acggacttgt
     4201 ccctgttcat cccatgttaa agcgaagaca ccattattcc aaggagcgac aggatcttca
     4261 atgatgaaat gaaaagcatc agctgttcca acaaacggaa accgttgaag gaattctttt
     4321 acatcaacga tccgagccat aaaatatggt tcgatctgct ctttgatctg actatcttca
     4381 atcaaaaatg ctaaaggctc atttttataa atatctccat gtacccagta gatcatggaa
     4441 aaatgtgcgg aaataaagtt ccataagcca tttcgagctt cttgatcaag atagaacatt
     4501 tcttttacgt gaaatatttc ttcagctacc cagtagaaca gaacacctct tggttcatgg
     4561 ttgctatcgt agtagacagc ggctgtgcgc tcatcttcat tttcgaaacg ccaatactct
     4621 tcccaatgaa aatcactgcg gaataaagca ccatggtttt gttgggcaaa tttgtcataa
     4681 acggaaaata cgtctggatg atcaactggt aatcgctcaa ccataccact tactgggatt
     4741 tgtttaggta gctgtgtatc tctgatttta aaggaaagtt tatcagacat gatttcccat
     4801 cctttacgcc gatagtaggg gatactgtaa ggatacaaat aagagatcca ttgcttattc
     4861 ttgcgcatat tatccaatgc aacgataatt agatcttgca tcaatccatg gttagcatat
     4921 tctggataag ttccaactcc agtcacacca cccattttat aacgtgcacc gtgaatattg
     4981 acttcacaag gatagatagc gatttgagag atcagtttat tttcgtggaa ccatccgaac
     5041 actttcgata cttccaaaat cggttttttg gaacggataa aagctcgttt attctcaaac
     5101 ccgctttcct cgatgtctgc ttcagtcact tggaacacat aggaaagcaa ttcattgaat
     5161 tgatcgatat gttcttgagt gaccggtttt aattcaagat tttctctaaa atctttttga
     5221 tccatttttt catctccatt tattagcttg ataacagtat agcaaaattc tacaaaaaaa
     5281 acttctatag ctgactaatt aaaaactctt taaattactg cttttcgttg gtataatgga
     5341 aagtgctgat tatatgaaaa gaggagacgc tatggatata aagaaaatga aagaacgcca
     5401 agagcagatt cgtaattttt cgatcatcgc tcatatcgac catgggaaat ctacattggc
     5461 cgatcgtatt ttagaaatga cgcacactgt gacgtctcgc gaaatgcaag atcagctgtt
     5521 agactcgatg gatttggaac gtgaacgtgg aatcacgatt aaattaaatg ctgtagaact
     5581 caattacaca gcgaaaaatg gagaaacata tatctttcac ttgattgaca ccccagggca
     5641 cgtcgacttc acctatgaag tctctcgaag ccttgctgcc tgtgagggtg ccgttttagt
     5701 ggtcgatgca gcacaaggaa tcgaagcaca aacattggcc aatgtttatt tagcgttaga
     5761 caatgatttg gagatcctgc cagtcatcaa taaaatcgac ctacccgcag cagatcccga
     5821 acgtgtccgt caagaaatcg aagacgtaat cggaatcgat gctagtgaag ctgtattagc
     5881 cagtgccaaa tcagggattg ggattgaaga tattctcgag cagatcgtgg aatatgttcc
     5941 tgcaccaagt ggagacttag atgcaccgct aaaagctttg atctttgact ctatttatga
     6001 tagttaccgc ggtgttgttc taaatgtccg gatcacggac ggtatggtca aacccggaga
     6061 caaaatcaaa ctgatgagta atggcaaaac atttgatgtt acagaggtcg gggtcttctc
     6121 gccaaaagca gttgctagag actttttgat ggtcggtgat gtcggttata tcacagcaag
     6181 tatcaaaact gtccaagata cacgagtagg ggatacagta acgttagcag acaatcctgc
     6241 cgctgaagct ttaccaggtt accgaaaaat gaatccgatg gtttattgtg gtctttatcc
     6301 aattgatact tctcgttaca acgatttgcg ggaagcttta gaaaaactgc aattgaatga
     6361 tgctgcttta caattcgaac cagaaacctc tcaagcatta ggttttgggt tccgctgtgg
     6421 attcctcgga cttcttcata tggatgtcgt ccaagaacgc ttggaacggg aattcaatct
     6481 agaattgatc acgactgcac catccgttat ttaccatgtt aataaaacgg atggtacgac
     6541 tgctacagta gataacccgg cagattttcc tgaacctgta acgattcagg atgtagaaga
     6601 accattcgtc aaagcacaga tcatggtccc aaatgatttt gtcggtgcag taatggaact
     6661 ttctcaacga aaacggggag aattcattac gatggattat ttagatgatt accgagtaaa
     6721 tgtcgtctat aatattccgc tttctgaaat tgtctttgac tttttcgaca aattgaaatc
     6781 aagcacgaaa ggctatgcct cattggatta tgaaatgtct ggttatcaaa aaagcaagtt
     6841 agtgaagatg gacatcttgc tgaatggaga aaaagtcgat gcattaagct ttatcgttca
     6901 ccgagacttt gcctatgaac gtggaaaagc aatcgttgaa aaactgaaaa aactaatccc
     6961 acgccaacaa tttgaggtgc caatccaagc agctattgga caaaaaatcg ttgcccgttc
     7021 agacatcaaa gccttgcgta aaaacgtctt ggctaaatgt tatggtggag atgtttctcg
     7081 taaacgtaaa ctcttagaga aacaaaaaga agggaagaag cggatgaaac aaatcggctc
     7141 cgtcgaagtt ccgcaagaag ccttcatggc cgttctgaaa atggatgagc aagatagtgt
     7201 gaaataactt ataatcaatc gaaaaaccta ttaaataaac ctttttgagt agatgcaaca
     7261 ctgaggatta tctgtataaa agattttaaa ctgtcatttg gttatcacgg cgatactaaa
     7321 attaacaaaa ttggaatatt tttcttgaag atttttagct gtcagtatat gatgaaagca
     7381 tctcatagga ggtgcttttt tcatggttga taattcaagt ggaagggttc ttaaatctct
     7441 aagaaaagag aaaaaactat ctcaaaaaaa gttagctgat ttagcaggta tttcacaaag
     7501 tactttagtt aaatatgaaa aagggtcaag aaaaatccct aaagacgtag ataatactct
     7561 aagcaagatt ctgaatatag aaactctaat aaaagatgag gaa
//
LOCUS       DADVXV010000107         7601 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.110, whole genome shotgun sequence.
ACCESSION   DADVXV010000107 DADVXV010000000
VERSION     DADVXV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.110"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(943..1356)
                     /locus_tag="KB969_002553"
     CDS             complement(943..1356)
                     /locus_tag="KB969_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBB6870474.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1812..2297)
                     /locus_tag="KB969_002554"
     CDS             complement(1812..2297)
                     /locus_tag="KB969_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870475.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2436..2651)
                     /locus_tag="KB969_002555"
     CDS             complement(2436..2651)
                     /locus_tag="KB969_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBB6870476.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2875..3675
                     /locus_tag="KB969_002556"
     CDS             2875..3675
                     /locus_tag="KB969_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBB6870477.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3694..5562
                     /locus_tag="KB969_002557"
     CDS             3694..5562
                     /locus_tag="KB969_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBB6870478.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5555..6046
                     /locus_tag="KB969_002558"
     CDS             5555..6046
                     /locus_tag="KB969_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBB6870479.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6034..6588
                     /gene="srlA"
                     /locus_tag="KB969_002559"
     CDS             6034..6588
                     /gene="srlA"
                     /locus_tag="KB969_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBB6870480.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6606..7601
                     /locus_tag="KB969_002560"
     CDS             6606..7601
                     /locus_tag="KB969_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBB6870481.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2708 a         1213 c         1443 g         2237 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatttca tctaatacga tacaaaggct atctttctaa tttgaaaaag
     1501 ggatcattaa aataataaga agaaaatatg tcaaaaggta aaaaagtaaa ttcttctatc
     1561 caaatataga aaaattgaat ctagaaaacc gcccgacaat aaatttcatt aactcagttg
     1621 accgaaaatg aagtagatac caaaaattta tcaagagagc aagtagagaa gtgagtatat
     1681 tcataagaga aatagctgta acgaattatt aggttaatgc aaatgcttat ttatactccg
     1741 tataactttc tcagaaaaaa tgataccaat aatgacttgc tagtactgta aatccgtata
     1801 atatcatcta atcaaaatgg tgttccattt gcatctgtca tcgtaatcga tccttcgggt
     1861 gacactcgat aaaaaccaac gcttccagat cctccttggg aacggatttg tttgctggaa
     1921 gctgtgaaca aataatctcg atcaattttt tgataaaagc taataacaat atcgtcactt
     1981 tgtaattcgg aacggtgggc aataagaaat agaagtgctt tgtcagagtt ttctaatgga
     2041 agagaaggta cagtgctttc ttgcatttca gatgttgaag aaatgctaaa cgactgaata
     2101 cttgattggc tatgttgcga atctacatta ccagtagaag tattagtaat ggaagtagta
     2161 gaagtacttt tagttgaacc aacctcagtt gttgaaatgg ctgctgaaga ttctttaaca
     2221 gaattctttg ttttatatcc acaggcagaa aaaagtatta cagttcccaa caagcctgcg
     2281 taaatccctt tatgcatgat agctcctcct aaaatagatt atctttattc agtatatcac
     2341 ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct tcccaataaa gggaaggttc
     2401 atgaagataa taactttttt aataattata gctttctaat atctttcatc aacttttcta
     2461 gtaatcattg ggaaaaattt caagcagtag atcgcacaaa tacctacgac gatataaatg
     2521 atcttcgcaa aaatagttgt tgaaccacca gcaatcatag ctactaaatc aagttcgaac
     2581 aagcctacca acagccagtt caaccctccc acaatcaata aagttaatgc aatagcatct
     2641 aaagttttca ttagaattct cctttcttaa atgataaaac aattatatat caaaaagaga
     2701 aacattgctt atataacgct caggaatttt agcaatctat gcaaaaagat gaaaattttt
     2761 tttgctcttc cattagtaca cattttttag ctgaagctgt aaatttcatg tcttaatttt
     2821 ttttagtgag cttttatact ggatttgtaa gaaaaaagaa ggagaggatc acatatgtcg
     2881 gattggttgg atattgcagg aaaagtagta attgtaactg gaggttcctc aggaattgga
     2941 agaagtatcg tcgaaaattt gttgaagcag aatgcacaag tagcgaattt tgatgtaact
     3001 gaatgccgta tacagcatga aaacctacta tctttaaaag tcgatgtgtc ttctaaaacg
     3061 gacatagaag aagggatata taaagtaatg aaacatttca agacgatcga tggtctagtc
     3121 aataatgcag gaataaatat tccttctctt ctaatagata gaaatcatcc aaaaagcaag
     3181 tatgaattat cagaacaagt ttttgataag atgatcgctg tcaatcaaaa aagtgtatat
     3241 ttgatgagcc aagcagttgg aagaatcttg gtgcaaaagg gatcaggagt gatcgtgaat
     3301 ctttcttctg aatcaggatt ggaaggatca gaaggacaga gctgttatgc tgctacaaaa
     3361 gcagcgatga acagttttac tcgttcttgg gcaaaagagt taggaaagag gaatgttcgt
     3421 gtggtaggtg ttgcaccagg gatactggaa gaaaccggtt tgagaacaca agaatatgaa
     3481 gaagctcttt cttatacgag aggtataagc gtcgaacagc tgagaaacgg ttacagtcga
     3541 acaagtacga tccctctagg aaggagtggt aagctgcaag aagtggcgga tctagtctgc
     3601 tattatcttt cagaaagatc aagttatatc actggagtca cgactaatat ttcaggaggt
     3661 aaaacaagag gataaaggat aggggggacg cacgtgacgc tagtaaacag atggtaccaa
     3721 ttattgaaat tactagtcac tcacaagaaa gtttcaatcc aggaagtgca aaaagaaatc
     3781 aaaaccagta atcaaaccat aaaaaaagat attggggagt tgaatgaaga aattgccggt
     3841 attgcaaaaa tcatccaaaa aaacaaacat tttgaacttg aaatttatga ttttgatttt
     3901 tttgatgaga tcatgcaagg aaaattgaaa acagccagtg atttcaattc ggcatccaaa
     3961 agaatcgctt atttactaaa taggctgatc gaaacagagg atttcttacg tatggatgat
     4021 ttgtctgaag aagtcggtgt cagcagagga acagtggtca aggatctaaa gacattaaaa
     4081 gagatgatca atgattttga tgtaaagatt acaggcacac caaataaagg actaagaata
     4141 ataggagatg agctagaatt acgactactt ttattttatt ttgtttctcc ctacttttca
     4201 gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa tcaaacattt tcagaagaag
     4261 acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag ttatcggtat ttctttgaat
     4321 agaatctcta gtaactatct gttgaagaag cccatcaatc gttacagtgg gtgttttgaa
     4381 tatatccaag aattcaatga actgatcaat cagttggaag aaatctatga actaactttg
     4441 agccaatatg aaaaagattt tatcagtttt cctttgaaca tcatcaacac aagtataacg
     4501 atgataagga aagctaactc tgatttgcgc ttatatttcg accccatgat gatgcgtatt
     4561 cgacgattag atctcattga tctggatgag tccttcttat atcaagagat gaaacagcac
     4621 ctctctttat tgataaatcg ggtaattttt cgttatcgat tgactgattt attttatggt
     4681 gagatagaaa aaaagtatcc tttttcttac caaatcgcta gcgaatgcat acaagcatta
     4741 gaagctatct tgcaacataa gatctctaaa gtagagatca gctacctaac gttgtatttg
     4801 gagttagcat ttcgatatca aaaagagcat ttttcctcta aaaaagtagc cattgttcat
     4861 acgacaggaa aaggaacagc attaatgatc caaagacaaa tcaaaaggat attggggagg
     4921 gatatacaaa taacacatgt ttcagaagaa caatatgaaa aagtagatct aaacaaatat
     4981 ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg aagagacacc ggtgatccat
     5041 ttgactaatc tttttgatga ctcttggtta agggcacaat ggcaaaaagc aaaaaaaaag
     5101 cgattagccg ggtttcattc tactgttttt ttctatcaaa tatggaaaga aaaaaagacg
     5161 tatcaagaat atttaaacaa attagtcgct cctttgatca gaggctatta tgtggatgaa
     5221 gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa gcacatttgt taacaaagaa
     5281 tttgcttttc ctcacacaac caaccagcta tctcaacaca ttgttttatc agtagggcta
     5341 ataactgatc aaggtttagc agaaacagga ggaaatggag ttattttttt atttgccata
     5401 cctgaagaaa tgacggctga agttgagaat gaattatttg agctatacga tatcctattt
     5461 gaactcataa aaatgggaat agatgagttt attgaattag caccgacaca agaatcattt
     5521 ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat gatatgtatc tattcatagt
     5581 tttcgcagct tcagcttatg tgctgcaagc agttatcagt tggaagcaac taaagcattt
     5641 caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta gcgattggta aacgacctgg
     5701 gaaaatccgt tcaggcacga ttgttatgct agctatagac gatcatgatc aagttttaga
     5761 agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt cattcattac ctgtctatgc
     5821 gggtgaagat atccattaca tcgatcgtta ccatccctca gttcgagcgg aagatcgttt
     5881 gacacaagca gctttagaaa atgccagaga agtatactta cgaatagagg caggaaatga
     5941 aaaaagtgaa caaccttcat tgccttttat tgctatgctc aataattttc ggatatggaa
     6001 aagtacgatc aaagaaaaaa ggagtgacaa acgatggata tcataacaaa atttgctgag
     6061 ggatttatga ggctgttcca aacaggtgca gaaacattca taagctggat gacaggaatc
     6121 gtaccagttg tcttgatgct gatggttgca atgaatacgc tgattgcttt tttaggtgaa
     6181 gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc cgcttactcg ttaccttgtg
     6241 ttaccgttct tatctgcttt tatgttggga aatcctatgt catttacaat ggctcgtttc
     6301 cttccagaat actacaaacc aagctattat gctgctcaag ctcaattttg tcatacgagc
     6361 aatggtgtat tcccccatat taatcctgga gaattgtttg tatggatggg gattgctcaa
     6421 gggatcgaaa ccttagggct aaattcgatg gagctggcta tccgatactt gcttgtggga
     6481 ctgctgatga actttattgg tggttggata actgatttta ctactggatt tgtatgcaga
     6541 cagcaaggaa tcgttcttag caaaaaagta gagctttcag ttgattagag aaaggagagt
     6601 tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg cgggtatgga ggtcctttga
     6661 ttattaggcc gacaaaagat aaacacaagt tcatctatgt cacaggtgga ggtgagaggc
     6721 caatgatcgt agataaaata gaagaactga caggtatgga gtctatcaat gggttcaaaa
     6781 catcaatacc tgatagtgaa atcgcgcttg caatcgttga ctgtggaggg actcttagat
     6841 gtggaattta tcctaaaaaa gggataccaa ccatcaatat cgtttccaca ggaaaaagtg
     6901 gcccattagc acaatatatc actgaagata tttatgtttc agcagtaggg ttagaacaaa
     6961 tacagccact aatggaaact gatgataaca aagaaacagt aaatactgca tctccagata
     7021 aaaagtacaa atatgatact tctaaaaaga taaccgagca aaaagcagag cagcaaaact
     7081 ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc tacattcaat caatcagcaa
     7141 gagaagcagt agatacgatg atccggacag tgatcccttt tatggctttc gtttcccttt
     7201 tgattggtgt gatacaaggt tctgggatcg gtaatgtatt tgctaacatt atggcacctt
     7261 tagcaggaaa tgcagttgga ttaacaatca ttggctttat ttgttcactg ccatttttat
     7321 ctcctttgct tggtccaggg gcagttatta gccaagtgat tggaacattg atcggtgtag
     7381 agattgggaa aggaaatatt cctccccaat tagcattacc ggcactattt gctatcaata
     7441 ctcaaaatgc atgtgatttt attccagtcg gtctaggttt ggaagaagca aaagctgaga
     7501 cagtagaagt aggtgtacca tcagttcttt attcaagatt tcttaacggc atcccacgag
     7561 ttatcattgc ttgggtagca agttttggat tatatagctg a
//
LOCUS       DADVXV010000108         7392 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.111, whole genome shotgun sequence.
ACCESSION   DADVXV010000108 DADVXV010000000
VERSION     DADVXV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7392
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.111"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(205..1653)
                     /gene="cls"
                     /locus_tag="KB969_002561"
     CDS             complement(205..1653)
                     /gene="cls"
                     /locus_tag="KB969_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBB6870482.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1805..2698)
                     /locus_tag="KB969_002562"
     CDS             complement(1805..2698)
                     /locus_tag="KB969_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6870483.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2682..3368)
                     /gene="ftsE"
                     /locus_tag="KB969_002563"
     CDS             complement(2682..3368)
                     /gene="ftsE"
                     /locus_tag="KB969_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBB6870484.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3473..4574)
                     /gene="prfB"
                     /locus_tag="KB969_002564"
     CDS             complement(join(3473..4501,4503..4574))
                     /gene="prfB"
                     /locus_tag="KB969_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBB6870485.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4700..7234)
                     /gene="secA"
                     /locus_tag="KB969_002565"
     CDS             complement(4700..7234)
                     /gene="secA"
                     /locus_tag="KB969_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBB6870486.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1976 a         1639 c         1289 g         2488 t
ORIGIN      
        1 tgctatactg gctttgaaat gtgtctcttt taatagcata tattagctta tttcttgctt
       61 tccccaaaaa acaagagata ccccaaagtt aatttcgctc atgcgagacg ctttctccat
      121 ttctgacgta ctctcagaaa tggccccgtt aaaaaaggac acgagatctc catctgttga
      181 tggttctcat gtccttttta tgttttaaag gagcggcgaa atcaatcttg ctaatccttc
      241 tttcatcttg atgattattc ctcggttttc atacatttct tttgtgagat gcgtagaaat
      301 tttcgagtct tcaaaaaaag cttttcttac acgtgaagcc attcgttcat cataaaccag
      361 tgtattgacc tcaaagtcca agcgaaatga acgaacatcg atatttgctg agccaactga
      421 aacaatgcca ccatcgataa tcatcgtctt tgcatgaata aatccattct catatgtttc
      481 gatccttgct ccatactcga tcagctctgc agcgaaagaa tacgttgccc agtaaacgag
      541 aagatgatct ggtttgttag gtatttggat atgaactttt acgcctgaaa gaagagccaa
      601 cttcagtgct tcatgaatcg atccatccgg tatgtaataa ggcgtttgga tcaatatctc
      661 ccgtttggct aacgaaatca ttttcaaata agtcattttg atttgttcat gttcggtatc
      721 tggtccgctt gtcacgattt gaacagctat atcaccagta gtgtgaatgg acggaaaaaa
      781 tttgggagaa tagcctactt cttttgtatg ctgagaattc cagtccatca aaaaacggtt
      841 ttgcaaggta tacaccgctt ctccgtaaat acgcaaatga ttgtctcgcc aataaccaaa
      901 tttctttacc aatcctagat attcatttcc aacattgaac ccacctgtat atccgatttc
      961 cccatcaata actacgattt tacgatgatt gcgataattg atccgaggat taatatacgg
     1021 aacaaataga ggaaagaaaa atgcgacttc tccgcctgct tttttcaaat tctgaaaaaa
     1081 gctggaagaa acttgtgtgg aaccccatgc atcaagaagg actctgactt ttacccctcg
     1141 tcttgccgcc tctgtcaatg catctcgaac ttcttcacct aatgcatcac tgcgataaat
     1201 ataatactgg aagtggatat ggtcttctgc ctgcttgata tcttcaatca gcgcatcgaa
     1261 tttttcacga ccatctgtaa ataaagtgat ttcattttta gtcgtataga gcgtactttc
     1321 aaataccgtg agcatataga tcaattgttt cacatctact tgtccagtag gcggatgagg
     1381 ataaagccct cgcatcaatg cctgtttgtc ttcttcaatt tccaggttct taccgatttt
     1441 cccttggatc ttcaaatcaa agattttctc tttggaaatc cctcttccta aaaaaatata
     1501 taaaataaat cctacaactg gaatgaacat caaaacgagc agccatgccc atgtttgagc
     1561 agtttccttt ctttctcgaa aaacgatgat aaaggaaagc aaaatattca taatcaaaag
     1621 gatcgtaaaa aaattgtcaa cgataatttt cacggcttca cctcttcttc taccaactta
     1681 agaataccca agttgttttt taaagtaaag ggaaaaaagc cgcttccttc tattctccta
     1741 gccaataaaa aaagaaagct ggaacgaaac tgtccaactt tctcatttta tttatattgt
     1801 ggtattagaa tttcaagaaa cgtctcatag aaatgatcga gccaagtgaa ccaatgatca
     1861 caccaatgcc gaccattaaa agattgattt tccaaacgat attttgtgga tgaatcaatg
     1921 aataatggga acgtaataat gatggattga tcaattggaa aaaccatgca taaccaaatg
     1981 tgatgatcaa aattggaaga attgcaccga tcagaccgat ccagccacct tcaaggaaaa
     2041 acggccagcg aatatatcca ttttttgcac cgactaaacg catgatttga atttcacgct
     2101 gtctagacaa aatcgtgatc cgaatcgtgt tcgaaatgag aaacatcgct acgaacagca
     2161 gcaatgccgc tgcaactaat ccccatgtcc gaactgcacc agcgatttgg aaaatccgat
     2221 ctgaggaagc tccaccgtaa tcagaacgag aaacattctt caaatctgct gcttcttctg
     2281 ctacttgttt tgtataagaa ggatcagtag cacttactac atacacatca tataacgggt
     2341 tattgtcacc ttcaaacaat ttccaggaat cacccatttc gttttggatt tttttcaatt
     2401 cctgttcttt gcttgaaaat tcaacttttt taacatgatc taagtcattc aattcttttt
     2461 ctagcttttt catctcttcg tcttttgtac cgatatctac gaatacagat acatcaacgt
     2521 ttccttctat atcctgagct aatttagttg cattcatgat aactgccatg aatacaccga
     2581 ctaaagtcaa cgtgatcgtt accgcactga ctgaagcaac tgtcatccag ccgttacgtt
     2641 tcaaactctt gatactttct aataaatggc ggaaaaaggt tctaatcatc gtatccatat
     2701 tccccttccg cttgatctcg aataatgcgg ccgttttcga tagcaattac tcggtgccga
     2761 atcgtattta cgatcgtact gttatgtgta gccatcacga cagtagttcc ttgggcattg
     2821 atccgatcta ataatttcat gatttcccat gagttttctg gatccagatt tcctgtcggt
     2881 tcatccgcga taagtacttt aggcgtattc acgattgccc gagcaataga gacacgttgc
     2941 tgttccccac cggataattc gctaggaaag actcgaactt tgtgtttcaa accaacaagg
     3001 tccagcactt ccattactcg ttttttgata tctcgaggtt ttctgccgat aacttgcata
     3061 gcgtacgcaa cattttcata tactgttttt cttggtaata atttatagtc ttggaacacc
     3121 acgccgattt ctctgcgtag ataaggaact tcgcggtttt tgattgctat tagatcatga
     3181 cctgcgacgt tcaaagttcc ttttgaagct ttttcttctc gatacatcaa tttgatgaat
     3241 gtagatttac cggctccaga cggaccaacc acatagacaa actctccttg ttcgatgaca
     3301 atcgagagat tgcggatagc ggtcgtacca tttgagtact tcttcattac atccttcatt
     3361 tcaatcatgg cgttctctcc atatcttttt cagtctttag ctattatagc atggcaatgt
     3421 ttcaacatgc ttgcaaaatc ttacaatttt atttcaattt aacaatgggt tcttattgta
     3481 gatgcatttt taaatagccg tcaataaata aatcaaggtc accgtccata actgcttgga
     3541 catttcctgt ctctacgttt gtccgatggt cttttaccat agaataggga tggaaaacat
     3601 aagaacggat ctgtgaaccc cagccgattt ctttttgttc tcctcgaagt gcagctgctt
     3661 cttgttcttt cttttccact tctaattgat aaagcttagc ttttaacatc cccatcgctt
     3721 gctcacggtt tttcaattgt gagcgttgtg cctgactagc tactactgtt cctgtaggca
     3781 agtgagtgat ccgtacagca gattctgttt tattgatgtg ctgaccacct gcaccacttg
     3841 ctcggtacgt atcgattttc aaatcatctg gattgatttc tatatcgatc gtttcatcaa
     3901 gctctggcat cacatctacc gaacaaaaag aagtatgacg tcgtttcgct gagtcaaaag
     3961 gcgaaatccg tacaaggcga tgaacacctt tttctgattt tagataacca aaagcgttat
     4021 gtcctttaat cagcagggtc acactcttga tccctgcttc atcacctgct tgataatcta
     4081 gtgtttctac ttgatagcca tgctgctctg cccaacgtgt atacatacgt aaaagcatgc
     4141 tgccccagtc ttgggactcc gttccgccag cccctggatg caattcgacg atcgcattgt
     4201 ttcgatcata aggtccgtct aacagcatag ataattcata cgtcttcatt ttttcatcta
     4261 atgcattgat acgtgtttct gcttcttctt gcattgctgc atcaggttct tcttgcagca
     4321 tctccaccat caattcgatt tcttctagtt cttcggcaag agaatggaat tggtcatagg
     4381 tttctttatt agcgttattt tcgctgatca ctttttgtgc ggcttcgctg tcatcccaaa
     4441 aaccaggttc agccattttt gcttctgctt ccgcgatgtc ttcttccagc tgatctaagt
     4501 caaagagacc tcctgaaact tgtgaccttt tcctgcattt ctgtcaggag atttcgaatt
     4561 tcggatattt ccatgttttt tccttctttc actatacttt tttcattata tctagtctaa
     4621 cagaatcagc aaataacaga aagaaggtga gacgaattct taaaaaaaga atttgtctca
     4681 ccaatcctgc tgtcagaaat tagtttgcat tttttccatg acagttctta tattttttcc
     4741 cgcttccaca aggacaagga tcatttcttc cgaccttatt cacatggatt ggctgttttt
     4801 tcgcgctagt attactattt tctttggcat ctccgtcttc tgagtgagaa gctgttcctt
     4861 gagaaacctg ttcacgctgt acgttttgac ggatctcagc tttcataaag attcgagtga
     4921 cttcatactc gatggcgcct accatatctt caaacatctt atagccttct gtttgatatt
     4981 cgactaatgg attgttctgt ccataagcac gtaagccgat tgactgacgt aattgatcca
     5041 ttgcatcaat atggtctgtc catttagagt ccacaacacg caagatcacg actttttcaa
     5101 attccaacag ttgctctgga ccatttagtt gagccgcttt ggtattaaat acttcttgtg
     5161 ctcgttcgtt tagatactct ttgatctcct gagctgtttt tccttcgata tctgcaagag
     5221 taatgctatc ttcatggaca agagtactgc cggcaaaatc gatgatactt tccaaattcc
     5281 aattttcttt ctctaattgt gtatgcgcat ctactacacg actgattgtc cgtttgacca
     5341 tgttcattag tggcttggat aagctttttt cttccatgat tacttcttgt cgctgtttat
     5401 agattacttc acgttgttca cgcatcacat catcgtattg taagacgttt ttacgtgtgt
     5461 catagttatt tccttctaca cgtttttgtg cagattctac ttgtttcgtc agcatcttgc
     5521 tttggataac agcatcttcc tcaccgatct tcatccgatc taagaaagct ttgattcgtt
     5581 ctgaaccgaa tcgtttcatc aaatcatctt ccaatgacaa gtagaactgt gacataccag
     5641 ggtctccttg acgtcctgca cgtcctcgaa gctggttatc gatacgacga gattcatgtc
     5701 gttctgtccc gataactgct agaccaccaa gttctcttac cccaagtcct aacttgatat
     5761 ctgttccccg accagccatg ttggtagcaa tcgtcacagc acctttttga ccagcattca
     5821 tgatgatctc tgcttcttta aagtgatttt tcgcattcag cacttcatga ggaatacgtt
     5881 cttgattcag catatctgat aataactcag atgtttcaac cgcaacagtt ccgactaaca
     5941 caggttgacc tttgcggtag cgatctttga tatcttgcac gacagcgtgg aacttgcttt
     6001 gtaatgttgg gtaaagcaaa tctggacgat catcacggat aaccggacga tttgtcggaa
     6061 tctggtatac ttggatgtta taaatttctc tgaattcttc ttcttctgtt ttagctgtac
     6121 cagtcattcc cgcaagtttc ttgtacatac ggaaatagtt ctggaaagtg atcgtcgcca
     6181 tggttttcgt ttcgtcttcg atctctacgc cttctttagc ttcgattgct tggtgaagtc
     6241 catctgaata acggcgtcca tccatgatcc gaccagtgaa ctggtcaaca atcagtactt
     6301 ttccgtcttg gacaacataa tcgatatcta aaagcatgat atagttggct ctcaatgctt
     6361 gatccaagtg atgggtcaat gcagtatttt caatgtcgta taagttatcc aaaccgaatg
     6421 tttcttctgc tttttcgatc cctgcttcgg ttaaactgat tgtttttgat tgtacatcga
     6481 ttttataatc ttcttcttct ttcaaacgtt tcacgaagtt gtctgctctt gtatataaag
     6541 ctgtggattt ttctgcttgc cctgaaatga tcagcggcgt tctcgcttca tcaatcaaga
     6601 ttgagtcaac ttcatcgaca atggcataat tcagcggacg ttgtaccatt tgatggcggt
     6661 aaacgaccat attgtctctc aagtagtcaa atcctaattc attattcgta ctataagtga
     6721 tatcacaatt ataagcctcg cgtttttcat ccgaagattt tgagttgata ttcaacccca
     6781 ctgttaatcc taagaaatta taaagttcgc ccatttccgt cgagtcacgg gttgctaaat
     6841 attcattgac ggtaactacg tgtacccctt cgccagtcag agcatttaga tatactggca
     6901 tcgttgcggt caaggtttta ccttcaccag tacgcatttc agggatattt ccatcgtgaa
     6961 gcacgattcc acccatcaat tgtacgtggt atggatataa acctaataca cgttttgctg
     7021 cttctcggac gactgcaaaa gcttccggaa gtaattgatc taatgtttct cctttttggt
     7081 atctgccctt gaattcagca gtttttgcct gtaattgttc atcagttaat gctgccattt
     7141 ggtcagcgta tgcttcaact ttttttgcaa tgctatctaa acgttttagt tctttcttat
     7201 cgttttcgat aagtgaacga atcaaattgg ccatgcgttg tgtaatctcc ttttccttct
     7261 gtgtattatc cagactatgt agactttact tttcatttta tcattagtta tagataattg
     7321 aaatatctta agcgtattaa agtaagaact tcataattta ttcatatttc atctaaaaga
     7381 ggaggaaact ca
//
LOCUS       DADVXV010000109         6788 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.112, whole genome shotgun sequence.
ACCESSION   DADVXV010000109 DADVXV010000000
VERSION     DADVXV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.112"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(20..1786)
                     /locus_tag="KB969_002566"
     CDS             complement(20..1786)
                     /locus_tag="KB969_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870487.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(1746..3500)
                     /locus_tag="KB969_002567"
     CDS             complement(1746..3500)
                     /locus_tag="KB969_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870488.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3610..4179)
                     /locus_tag="KB969_002568"
     CDS             complement(3610..4179)
                     /locus_tag="KB969_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBB6870489.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(4197..5612)
                     /locus_tag="KB969_002569"
     CDS             complement(4197..5612)
                     /locus_tag="KB969_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBB6870490.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(5623..6291)
                     /locus_tag="KB969_002570"
     CDS             complement(5623..6291)
                     /locus_tag="KB969_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBB6870491.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(6421..>6788)
                     /locus_tag="KB969_002571"
     CDS             complement(6421..>6788)
                     /locus_tag="KB969_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6870492.1"
                     /translation="IEKSWRENFNELDPFINYIFENKRIFDLILFQSAGTKYQDIVEK
                     ITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYATFYDILKHSYSKEKTM
                     LLTRRLYQFSVPGWIELLS"
BASE COUNT         2309 a         1242 c          909 g         2328 t
ORIGIN      
        1 taatttaaag cctatttcat catcgtgatt gagcttcttt ttcatagacg aatttctcag
       61 atagtttagt tttctttatg agatttttgt atatttctga ccttcgatac aactcattat
      121 gagtaccttg atcaactagt tttccttgat ccatcactac aattttattt accttttcaa
      181 tagacttcaa gcgatgcgat ataattagta ctgtcttatc ttgtattaaa cgatttaaac
      241 tttcctgaat acgtttttca ttttccgcat ctaaactggc agtaatttca tctaaaatta
      301 aaattggcgc atttttcaaa aaagcccgtg ctatggatag gcgttgtcgc tctcctccag
      361 aaagtgaact tccgttttct ccgaccaatg tatgataacc gtcaggtagt ttttcaataa
      421 agtcttcgca gttagctaaa cgagctgctt ttttcacttc ctcatctgac gcttgactat
      481 ttccaatacg tatattttcc aaaatacttg tattaaacaa agttacctct tgaaaaacaa
      541 tagcgatttt gctaaacaaa gaagctggag atacacgttt aatatcatac ccatcaatta
      601 aaatacagcc ttcatcataa tcatacagtc tagacactaa tttcaagata ctagttttcc
      661 cggaaccact agcacctact aacgcagtca cttctccttg tttagccgta aaagagatat
      721 gatctaaaat tggggtattg ttatcatatg agaaagagac atctcgcaac tcaatgtcaa
      781 aagatttcag aggactatct gatccctctt ggatactggt ttccttcata gctctaattc
      841 gctgtatttt aggagctaaa taaaatattt caagcactgc ttctttcata gaatcgaagg
      901 aatcctttat ttttattgcg gctagtaagt aaccaacgac gtagagtata gtcacttcac
      961 ccgttaacag taagtgaaca cctactagaa tgactactgc taaactaaca tatgagaaaa
     1021 tagaggataa ggccatgact gaaaaagtac ttaattctac ctttaaatga atcctttcac
     1081 tctcttccat ttttttgaaa agtctgtctt gaactttttt agatagatta aagctattaa
     1141 tctcttgctg caattctata gtttcttgaa attcttccga gttctctctc aaagtatcgt
     1201 aatatttagt attggctttc gtttgggatt tctttgataa caagattaag acaaaactaa
     1261 ataacgttgg caaaataaca gctaatccca ttttgacatt accaaccaaa agcatcactg
     1321 aaataaaagg gaaaaacaga gccataccgc cggctttagg tattgcatga ctcatcgcat
     1381 gctcaatacc ttcaacgtca gacatgatag tttgagataa atctgataaa ttatgttttg
     1441 aaaaatagga taatggtaaa tttgacaaat cgtctgcaat ttgcactctt aaatgcgcac
     1501 tttctttata agtactatta tataagtttt catactccct atctaacaac caatacatga
     1561 aaagcaaagt aacaaacgat acggcaaaat aaagccaacg gggctttgta ttttctaaaa
     1621 ctaattcgtc tatcagcatc attataatga atgctggtac catattaatg cagtatacaa
     1681 aaaaactaga aatagaagct ttagttaaag cttctgcgcc ctgatcactt aaagcaaatt
     1741 tgtttttata aaaacttttc attgtcaagc ctccaatcat ttgcattctc ataattagtg
     1801 accaattgtt tatacacttg atgtttagcc attaattcat tatgatttcc acgttctact
     1861 attttccctt ctgacaagac aagaatttca tctacagatt taatgctgga taatcgatga
     1921 gctatcataa taactgtttt ttctttcatc agatgttgaa aagccttttg tagttcatac
     1981 tcattatctg gatcaataga tgcactggct tcatccataa taacaatctt tgcatctttt
     2041 aaaattgctc tggcaatagc tatacgttgt ttttctcctc ctgacagata aactccttta
     2101 ctaccaatta aggtatgctc tctttcggga aatttttcta aaatcgattc gcaaccggct
     2161 aatcttagcg cgtcaaatac tttacttgct ggcgcttgag gatttgctat agaaacgtta
     2221 tcgtaaatac tctgattgaa tagtttcgta tcttgaaaga caaaagcaat tgtgttaata
     2281 attgtgtctt ttgaatagtg atttaaaggc ttaccaccaa ttttaatctg tcccttatcc
     2341 acattgtaga aacctgaaat tagtttagct atcgtactct ttccgcttcc tgattttcct
     2401 actaatgcat aaattctttt ttgttctaaa actaagttga aattttctaa aacacactct
     2461 tctttgtatg aaaagctgac attttcaaat gcaatgtcac aatttttaat ctgtgtctcg
     2521 ttcccatatt ttagttggtc ttgcttcatt tctaaataaa gggagtctag tgtttcgact
     2581 gcatatcttg cttcaaacaa gtgcatactt acatacatta ttctcatgaa agaaacaaaa
     2641 ataattccac ttaaaaaaaa caacatcaac aagtcaacag ctaatatctt gggagtggta
     2701 agagaagtta taaaaaaggt tataggaact atcaaaatgc aaactatgcc aaaaaatagc
     2761 cattgaaaaa gaacaaaagg tgttttccca ctcaaagaat acttatatgc aaacttagca
     2821 taatcgttaa ttgctttatt caaggcttta aatgatgtta ctttagcacc aaatatcttt
     2881 ataacttgaa ttccgcggat atattctacc gtttcagagc ttaacacatc taacgattct
     2941 tgatattttt gaataaaatt tgtattctct gtcattttct ttaacaagaa tacaccaatt
     3001 actaacatgg cgattagaac caatccaatt ttaaagttaa tgaaaaagcc taaggcaact
     3061 gataaaacag gtgttactat ggcttgagca ctatctggaa tcaagtgagc aattgccata
     3121 tgtgttttag ccgcgttgtc atcaattgtc tttcgaatat atcccgaaga atttaaatca
     3181 aaaaaacgaa aacttgcttc tgttaaaccg ctaattccct tttttctcaa attagtctct
     3241 aagcgaaacc caaggatatg agaaaataag ccagaaaaaa tataaaataa agctcctaaa
     3301 gttaaccaag caacagtttg aaccgcataa ctcttagcta aatattcatc tcctacaata
     3361 attagagact gaagaaattt gtaaatactg taatatccat agactgttaa tacgacagaa
     3421 aaatcagaaa ataaagtggc taaccatccg tagtatttca ttttagggac ataactaaat
     3481 aattttttgt atactttcat tttttcctcc cccgcattca atttcttctc ttattcgttt
     3541 acaactgtta atgctttccg taatagcgta aattagagat gtacaaacag ataaaaggta
     3601 aactacgttc tattttttgt atttttttaa gacttttctt ccaatcaata caccaatcat
     3661 agataaactt gctacaacta acactgaaat gattccccat atacctaccg catagtggat
     3721 cattgcatcc attgttgcag cagattgtcc tttatctatc caatcttgac gaaaacgatc
     3781 tgtaaagaac catataggaa tccactgtcc ggcagcactg cctaattgca ttagagccca
     3841 agacgcaact tgaggaattg ctcgatcata tccaaataca gatagaataa tatcagctaa
     3901 gatcgccata ctaatcgaac tgataaacca aggtaagtac gccccgccca ttaacgtaaa
     3961 aaataacaat aaaacaattg tgtaaatagt aaaaattcct tttctagggt agttatagct
     4021 aatataaaca aatatgattc cagataataa tccaaaaatc ccgggggata tgctgtgacc
     4081 aaacgcccca ccaatactac taaccattat tgaaaaaaag taaattacta gggaaataac
     4141 tgtagctaaa ccaataaaaa tataatcttt tgttttcata tatattctcc tcaattctat
     4201 ttcgttatgt cattaaaaat ctgttctatc aaagttgaat cttctactct aagttttata
     4261 tcttttttta ttccaccatt ttttaaataa ataattctat tgcatgtttt ataaagaaat
     4321 tccggatcat gagtagctat aactactgca cccttttctt ttaagtcttt aataaggtca
     4381 gcaatccttt ccatattaat ataatccaac ccacttgtag gttcatcaaa tagaaataaa
     4441 ttagtttttg acaatgaagc tatagaaacc aataatcttt gtttttctcc accggataaa
     4501 tcaaacggta attgatcttt cattttataa agttccattt tttttaaaat tttttcttgc
     4561 tgatctttac taactatttc attccccagg gctaactcgc tcctcactga ttctgtgaaa
     4621 aattggtaat ccatttcttg cattactaaa aacggcgatg acaaattttt tttattttcg
     4681 attatctttc ctttggtagg gcgaataatc ttcatgagta ttcttagtaa ggttgttttc
     4741 cccacaccgt ttttccctac caaaccaata acatctccaa ctttgacatc aaaatttatg
     4801 tcttttagaa tattttcata agtaatttct tcaactttta atacatctgc acttaccttt
     4861 tcgatatagg gaacttcaat cgaactatta aaaatgtcaa atttccttaa tgcgttattg
     4921 ttttcagttt ttaacaactg aatagttgta gtttttacag ttctattttt aacaaataga
     4981 acttgatcaa ttaattcttt caaatagtaa aaacgatgtt cagctataac aatagtaaat
     5041 cctttatttt ttaaatcaca aagtaagtca gcaagtttct tagtcgcttt gaagtccaaa
     5101 tttgaagacg gttcatccaa tataattaat ttagagttta gcgataaact acatccaata
     5161 gaaattttct gccgttcacc acttgatagc gaaaaaatgt ttttatctaa tatatttgaa
     5221 agatctaata attcagctaa ttcattgatt cttttatcca tatgctcttt tgtaaatcca
     5281 aagttttcca tcgaaaatac taactcactc gttgtatttg ttgtaaagaa ttgtcctcta
     5341 ggatcttgac ttacgtagcc aatatttttt gatatacttt cttgtgttaa ggattgtagc
     5401 gagttatttt caaataaaat ttccccaacc aattttccgt cataaagtct tggaataagt
     5461 ccattcatta actttaatag tgtggatttc ccactcccag aagaaccagt aatcaatgta
     5521 agactgcctt tttttattga aaaattaagg tcaacaagcg cttgttcctt aacatcctta
     5581 tatgaaaaag aaacattgtt aaattcaaac aattctttca cctcaaatca aaatacttaa
     5641 gaaaaaaata gtaacggaaa acaggatgat atagtctaat aagctcatgt ttgttttata
     5701 gtaagaactt cttttcacag gagattctat cccctttgtt attgcattag cggtcatttc
     5761 ttcagcaatc atagttgcac gtataagaac gggaactaac agaaattcca aatattgcag
     5821 aggctgaaaa aaagacaagc gaatgtttct catttttaaa gattctttaa tcattcttat
     5881 ttcagaacga taagtcggaa agaatctgat cactactgta atacttaaca ttattttttt
     5941 cggtaaatgt attttttcta aagaggataa taattcattg ctagtataga cactaaccaa
     6001 caaccatgag atcattacga ccggcaacat tcgaaataca atatataagg atgtcgcaaa
     6061 aaatatagta aaaaactcta tcttgatagc atcaataatt ttcattacta aaaacagaac
     6121 tgaataaatc aagatgaaat aaatacatgt ctttatttta cgaaacatca atactaaaac
     6181 tgtagcaata atgaaacacc ccacttgaaa tatatttccc tttcctaaaa aaataatgac
     6241 cggaaaaaaa atatttaaag taatcaaggt taacggattg atttttgaca ctctttcacc
     6301 tccaaaaaat aagatcgcac tgttatctta agctgataaa aatgcaccgt tattcagata
     6361 acagtgcgat cttatcaaaa agcataactg agaacaattc tcaatgcaag ctttttttaa
     6421 ttaactcagt aattcaatcc acccaggaac agaaaattga tacaatcttc tggttaatag
     6481 catagtcttt tcttttgaat agctatgctt caatatatca tagaatgtag cgtagaatga
     6541 gtaaatgtag aagtggattt cttcttcatt aaagactaaa ttttgattga tcattccgat
     6601 agtctttaac ttatctagac aacagactgt ctttttcgtc acaaatgatg taattttttc
     6661 aacaatatct tgatatttgg ttccagctga ttggaataaa atcaaatcga atatacgttt
     6721 attctcaaaa atataattaa taaatggatc taattcattg aagttctctc tccaactttt
     6781 ctctatat
//
LOCUS       DADVXV010000110         6665 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.113, whole genome shotgun sequence.
ACCESSION   DADVXV010000110 DADVXV010000000
VERSION     DADVXV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.113"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            215..631
                     /locus_tag="KB969_002572"
     CDS             215..631
                     /locus_tag="KB969_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870493.1"
                     /translation="MQHRQIRLYAGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPE
                     IHHYTSDKKILIISDLSLRHSQYIEEYISDILAVHKIHSETTAITEDQLSKYNLLEYD
                     LIVTNQPILNAHVPHILIDDSVSFANEEELIRLFEL"
     gene            complement(704..1351)
                     /locus_tag="KB969_002573"
     CDS             complement(704..1351)
                     /locus_tag="KB969_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBB6870494.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(1359..2045)
                     /locus_tag="KB969_002574"
     CDS             complement(1359..2045)
                     /locus_tag="KB969_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870495.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(2051..3124)
                     /locus_tag="KB969_002575"
     CDS             complement(2051..3124)
                     /locus_tag="KB969_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6870496.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            3346..4020
                     /locus_tag="KB969_002576"
     CDS             3346..4020
                     /locus_tag="KB969_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6870497.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            4025..5365
                     /locus_tag="KB969_002577"
     CDS             4025..5365
                     /locus_tag="KB969_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6870498.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(5514..6500)
                     /locus_tag="KB969_002578"
     CDS             complement(5514..6500)
                     /locus_tag="KB969_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBB6870499.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         2042 a         1259 c         1155 g         2209 t
ORIGIN      
        1 tacgattttt tcagaatttt cggagaaaga aaaaaatgaa atcagtgagc agatacgaaa
       61 aaatatgtcc tactgttcgt tttcatccgc tgattgcaaa gaaaaaaacg aagaatatgt
      121 tgttcaatta ttaacgcaaa tttatttttt ctcccgtatt ttcccatacg atacgactca
      181 tttgacgatc cgtgcaactt actttgcaca gcagatgcaa caccgccaga tacgtctata
      241 tgctggattt cgtgcagaac ttcaatttta ttccactcta ctgaatcaga atctgattta
      301 ttatttatct agctatatct tttggatgct tatcggtaat cctgaaattc accattatac
      361 ttctgataaa aaaatactga ttatcagcga cttaagtctt cgacatagtc aatatattga
      421 agaatatatc agtgatattc ttgctgtgca taaaattcac tctgagacaa ctgctattac
      481 tgaagatcag ctgtcgaaat acaatcttct cgagtatgat ctgatcgtta cgaatcaacc
      541 cattttgaat gcccatgttc ctcatatatt gattgatgat agtgtgtcat tcgcaaatga
      601 agaagaactc atccgcttat tcgagttatg aataatcaaa aaacagctat gtataaacca
      661 ccctgataaa aatttcagga caaatacaca tagctgtttc tttttattgt attccttcag
      721 caatccaacg agatttatag cgaaagtctt ttaacaactc ttcttttgtc caattatttg
      781 caatgagatc cgtcaaagtg ttcattacga gggtcatgga aaagtatagg aaactaactg
      841 cttcttccga cgattgaatg gagaaatgat tgattcttaa taattccagc catttttcgt
      901 tcattggaga atcagccgat agttctctac gtttggttgt ctgctgatca tttcgctggg
      961 ttaacaagta taacctttgc caatagatac tttcgtgatc taagtcgcag caccactcta
     1021 aatatttttc gatccccaaa aagaaatgtt gtttgttttc gctaatgaat tttaagatat
     1081 cttgatggac tatgtgagaa ctgcttttga tcgtatacaa ataagcatct tccaaatctt
     1141 gaaaatattt ataaaaagca ccgcgcgaca tccccatctt gtcaacgatt tctgagactt
     1201 tgacttggct gatgtgctgt gagcaaaata tctccagtaa taggtcatcg attctctgtt
     1261 tctttgcgtt cgataaattg aaaaaagttt cttttggcat ccacatctct cctttatctc
     1321 tgattatacg tggatagccc ttcattgtca tgaaggattc attccttctt tttctcttct
     1381 tctgtcaagt acccatcttc cattcgataa acgcgatcac tccattgaat catacggaca
     1441 tcatgagtaa ccataatagt cgctttttgt ttctcatgag cttctttaac tagtaatttg
     1501 acgacttcat atgcatgatc tgtatccaaa ctagctgttg gttcgtctgc taagatcaag
     1561 cttggctcat tatataaagc gcgagcaatt gccactctct gtctttctcc accagaaagg
     1621 tctttaggat aactattttt aagtgactgg atatctaaag attgcagcaa ggaatcgatt
     1681 tttgttgaat cttctttttt tgaagtaact tggtcaacta gttcaaattg ttcctttacc
     1741 gttaaaaaag gaatcaaatt agagctttgg agaataaatc ctatttcttt aaagcgtaaa
     1801 tctgctcgtt ttttttctgg aagctcagtt agtgagtgac cgttgatcac tatttctccg
     1861 gaagtcggtg tttgcaatcc tcctgaaatg gtaaggaaag tacttttacc tgaaccagaa
     1921 ggaccaatga tgctgacgaa ttctccttcc tttacataaa aatcaattgc tttcaaagct
     1981 gagacctttg tatgaccaga accaaatgtt ttggtaactt ttttcatcgt taatattttt
     2041 ttcattttta ttaacctcct attgctgtaa ttgggtctac tttggttatc gtacgtatcg
     2101 aaaacaatcc gcctagcatt gcgacaatga tcaaaatccc actatatagc aaccattgtg
     2161 accaaaaaac agcaaaaggc atcgcgcttg gtaaaatcag actagtcaaa taagcaaaca
     2221 aaagagcaag cagaacgcct accaccccaa caataaagga ctgtgctact aaagatttag
     2281 cgatgaagaa atttttgatc ccttgtgctt tcattactcc aaaaatagca gtcttctgaa
     2341 gtgtcatcac gtacatgaaa ataccgacca cggcagcaac cactaagaac aaaaagtata
     2401 tcatcgcatt taaggtcata ttttgggcag aatagccagg aatactttca atgaatgtcc
     2461 caatagttaa taactgtaga cccttcgatg ctttttcttt cgaaatttta gctgaatcct
     2521 ttattacgat cccattgatc ggctgttctt cttcagaagc aaacggctgt tgtccatact
     2581 tcaaagcagt ccacgtatct agggacgcat agatgacggg agaaactgtg taataagttt
     2641 caggaaagat accgacaatc gtcaaaggat cgtcgtaact gccaattttg atcgtatctc
     2701 caattttata gcctgaatca gccagatttt gagagatgat gatttcattc tttgttttaa
     2761 attcatgccc tttcgtgagt tttggtaata aaaatgcttc tttcgttgtg ccgaaaactg
     2821 taacattttc tttgtttttt cctttgattg ctccgctgta caatccgatt ggtgctttct
     2881 ctcctccttc aatgtatttc agatctcctc ttgttaattg tgaagctgca aatacttgat
     2941 ttgcatcctc cgacaaaaca atctcttgtg cgtcccaatc atcgattgct tttttaaact
     3001 cttctgaaag tccattcgct agtcctgaca acatgaatac gacatacgca atcaagaaca
     3061 taataccgac gatcaagcca tatcgtaatt tagaatagcg aatttctttg atagctagaa
     3121 acatttgttt ttcctcccta tgatagattg atagtgacaa aatgtcactt gttgaatagt
     3181 gtaactctaa agtgacaatt tgtcacttgt gttgtttttt tcttatcaat aaattgtcta
     3241 agacatcttt cgataaaacc ttaacatgag tcataaaaaa tttatttaag ccttatttat
     3301 gctttccatg ataaactaaa gtgaccaaat caatgaggtg ggaaaatgat taaactatta
     3361 gtagtagaag acgataaagt attatccaat aatataaaag aaatactcgc tgcaatcggc
     3421 gagataacac aagtttatga tggtagtgaa ggactgttcg agttggaaag tggagtttat
     3481 gatcttgcaa tcttggattt gatgatgccg gaaatgaatg gatatgaagt gttagcaaaa
     3541 atacggaaag aaaaaataca gactccagta ttgattttga ctgcaaaaga tagtttggaa
     3601 gataagattg aaggatttga acgaggtgca gatgattatc taacaaaacc tttctatcga
     3661 gaagaactga tcatgcgcgt gaaagcatta ttgaaacgct cgctaggtct ctttgatgaa
     3721 aatgttctga agtataagga tatcagttgt gatttaaaaa gcaatgaagt cttgtataaa
     3781 gaacaagttt tgcccataca aggaaaagag tttgaattgc tcgtttattt tttacaaaat
     3841 aagggaatca ttttgacaaa agagcagata tttgaccgga tctggggatt tgattctgat
     3901 acgacgatta cagttattga agtttatatg agcaacttac gaaaacatct gcgaagtact
     3961 ggattggata aagaaatcaa aaccttacgt aatgtcggtt atatactgca aagggtgtga
     4021 tgcaatgaat ggagatatta cacgaaagca acgtagtcgc ttttttgcga caaatgtagc
     4081 agcatttgct tttatctttt ttcttttggg attcattact ttacagatat taaaccaatc
     4141 tgcatacaga gaaacagatc tgtcattaga gaaaataaat tttgattctc gaacagtaca
     4201 attagagata caaagatatc agcaaggcga tcccttttta aacccgactc aaacggaaca
     4261 aaacagaaca aacatggaac agccattaat ggaaccatca aatgaccgtt ttaacactca
     4321 agtgatcttg tggtctaaaa atggtgagat attgaataaa gcagctattg gtgggcgttt
     4381 caaccaaatc aaagaattaa aaatggatac gaaaaatctg aataccatcc aaaatattga
     4441 attaaatgaa gacagtggct catctgccct ctctttccgt tcgattacga aaaaagcgga
     4501 gacgaatcaa gatggcgttg cctacatcca aattttagaa aatacaaatc aaatcaagaa
     4561 ttcattagcg acttttcgca cgattatgat tttgtgtatg attgtttttt ggattctctc
     4621 tattggtatc agttattact tgtctagtct aagcatgcgc cctattattc tttcttggag
     4681 aagacaaaaa gaatttgttg agaatgcttc tcatgaattg cgcacaccgt taacgattat
     4741 tcaaaatagt ttggaacatc tttttaccaa gcctaatcat actattattg aagaatccga
     4801 aagcatcgct caagcattgt cagagacgag gcgcctcact ggattgactt cggatttgct
     4861 gacaatcgct cggaatgatt ctgatcagca gctgctttca aagcaaatga tcaatacaca
     4921 agaatatatc gaacaacttg ttaaaccatt tcaagagatg gccatcatag atggaaaaga
     4981 gtttattctc cataacgatg caacattaga agtaccaatt gatgaaaaaa aaatccatca
     5041 agttttggtt attttgctgg ataatgcatt aaaatatacg aatccagaag ataagatcat
     5101 tttggattca tctgttaacc ataaagaatg gctgattcac gtaaagaata ctggcccttc
     5161 tatcagtgaa gaagatcaag caaggatttt tgatcgattt tatcgggaag atcaatctcg
     5221 ggcgaaagag actggcggat acgggcttgg cttggcaatt gcaaaacagg taatcgaaca
     5281 gcatcatgga cagatttctg tatccaatta tcttccacaa ggagtcgatt ttaaagtcca
     5341 attgccgttg aagcctaaaa aataatgctt atccctaaaa aagggctgtg acaaaaatct
     5401 tgtcacagcc cttttttgtt gcgaataaac ggtgttccag aagtagcttc ttcggaaata
     5461 agccgaaatt tctttaagct gaccacttct gtcacaacct ctttagctta cgcttacgat
     5521 tttttattgc ggtcttcaat gtgtacatca ccgcttgtgt caatatccaa ttcttctcgg
     5581 ctaacatctt ctgtcacttt ttcaacatct tcatgttctt ctttatgaat cccaacttct
     5641 tcacgaataa ctgtatgttt gcttacatct acttgctctt ctttgattgg gatagtaatc
     5701 gtgtcatctt ccaatttttc gtctgttccc tgtgaagatt gatctgttac tggtttgcgt
     5761 tcgatgacga tttcttcacg tttgaccggt acttctaccg tttcagtatc gttgaccaca
     5821 tgtttgtgga tgtcgacttc tccagttgtc acatcatgtg tatttacatc taatttttct
     5881 tcttttagtt gaattgtatc atcatctaga tttggtttgc gatcgatgtc ttcagtcttg
     5941 cttgtaccca ttgtatcagt ctcgccaggt acgtccatcg gatcagttcc tggtgtcata
     6001 ttcaatggat ccgttgtatt ttgaaagcct gtcgtgccac ctacgtccat tggatctgtt
     6061 ccagtgccag tttctaatcc agtccccatt gtgcttgctg ggctaacagt atcttgtgta
     6121 tccattgtat cttctgttgt ttctggctga cgatagcctt ttactgtgat gacaaatttt
     6181 ccatcagaaa tatctcctct atattgatat aaaggatcat tttctggtgt agccgtctca
     6241 gaatcatagg tatcaaaaga aaaagtatct tttatttttt cccataaaga acggtcttct
     6301 tcaccatcca tccgattttc atctgtttca acatctatac cagacaatcc gtcaaatcct
     6361 agtctagatg ctgcttcatc agtagtataa ataacgatat catctcgttc atacccttcg
     6421 ttacgcaacc gttcaattac tgataatgct tcttccctcg tactatagct tccgatgacc
     6481 gttaaatttt tctcttccat gtaaattcct cctagcaaat agatttatga ttggtatatt
     6541 gttacttata aatttattct ataggagacg attgttttct acaaatattt agattggaat
     6601 ttgattaaaa caatttaatt gaaatttgaa aacatttatg ttaatgaaag tcatattcta
     6661 ataaa
//
LOCUS       DADVXV010000111         6610 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.114, whole genome shotgun sequence.
ACCESSION   DADVXV010000111 DADVXV010000000
VERSION     DADVXV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.114"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            126..2801
                     /locus_tag="KB969_002579"
     CDS             126..2801
                     /locus_tag="KB969_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBB6870500.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGITKIEATFVEAQKKLWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            2983..3222
                     /locus_tag="KB969_002580"
     CDS             2983..3222
                     /locus_tag="KB969_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870501.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLDFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNRRVVKKWYLVHS"
     gene            3238..4611
                     /locus_tag="KB969_002581"
     CDS             3238..4611
                     /locus_tag="KB969_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6870502.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGEKAERPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLSYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEVHEARIVRYIFQLYLTKKYGYKKLCQRLTQQKLFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKATFLQAQEIRQSRCTAKKDTYLYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKRKVIQQKKQEAQWIKAFEEGNCSLEELKQQLQALQ
                     KPMSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDYVCRIEVTKDKTVCGIYFRQLTQ
                     NILERNE"
     gene            4615..6249
                     /locus_tag="KB969_002582"
     CDS             4615..6249
                     /locus_tag="KB969_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBB6870503.1"
                     /translation="MEMIQTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMGYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPRPILVKGTHEPIISEEDY
                     QKVQERLALEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQGEPIQVKDVQRILTSLDRFLAQSEKKQIKALYRTFIEKITFDPNHKEMLEITMK
                     FTHAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            6412..>6610
                     /locus_tag="KB969_002583"
     CDS             6412..>6610
                     /locus_tag="KB969_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870504.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYY"
BASE COUNT         2314 a         1066 c         1330 g         1900 t
ORIGIN      
        1 ttttttcttt tgtcaagatt ttgagtggga tatatttttg tagaactgaa gatcatgaaa
       61 ttatgagagg ttggaggtaa tgtagtcata caaataaaaa ttttttagaa agtgagtggt
      121 aattaatgaa aatgaatcac acttcaattc agaagcattt acaactgtta aatacactgg
      181 ggatttctta tgttaatttg agaacttttt ctacattaaa caagaaaacc gtttctcata
      241 ttttttctac tgcagattct caagcaatta ttaactattt agaaaaacag aaattgtctg
      301 aaggtacagt aaacataact tataatccta ttaaacaaga ggtgattaca caaaaaaagc
      361 attctgtgag agacaatgat attgaaaaaa ttcggtttgt atttattgat attgacccta
      421 aaaggaaaga gggaagtgca acagatagcg aaaagaaaaa ggcagaaaat gttatggaac
      481 aagtagaacg ttatttgaaa gaaaagagaa tagaatcatt tgtaaaagtt gatagtggga
      541 atggctacca tatttttctt cccataaatg aacaaccaaa taatcacgag acgattctta
      601 ctattcagaa ttttcttcaa ttacttcacc gaagatttgg agtagaagat gaagttgata
      661 ttgatacttc tgtttataat ccttcaagat tatgcaaatt agttggtaca ccagcggtca
      721 aaggaaagtc cacaaaagag cgtccgcatc gtttatctag tttcctttct attcccgata
      781 acatagatag aagtaattgt tttaaaattc ttgaacagat agttgaagaa aattccatga
      841 tgtcaacctc tagagtaaaa agccatccat cttttagaga agtgttacct tttattcaag
      901 cagactataa acaatggtta gctcactatc ctgaattaac ttataccata aaagagggcg
      961 atcataaagg agttacctta cttatatttg acgaatgtcc attaagaaaa cacacgaata
     1021 attctaatgg ttcttgtttg tctgttacgg ctgataataa gattcgattt cattgtctgc
     1081 atgcttcgga taaaaataaa gatattcaag actttgtaaa aaaatatccg ttgccaaaac
     1141 ctgtaaatcc ttctgtagaa tcattagaat ccaatcaaga atattatttt gaccagttta
     1201 aactgaatca agaaggagta tttttggtga aagaaggtca agaagaaaaa gttgcttgtc
     1261 cgatgtttat taagcaaata cgcaaaaata tcgaacaaaa agtcattaca cttgttcttg
     1321 cctattatgt cgatcattgt tgggatgaaa tagaaataga aggtggatgt ttacaaacta
     1381 ataattttaa acaattagca aaacatggct taatcattaa agctagaaga gaagctgaag
     1441 tcgttgactt tttacagatt caacgggaga atgctccaat cttttttgaa catgaatctc
     1501 ttggctggaa aaaagaaaat gaagcaatga tttttcagtt acaagattct tttggacgtg
     1561 aaattccttc tgtattaact aaaaactcat gctaccaatt aacaactaat ggtacagaag
     1621 cggaatttga cgcattggtt cataagtatg ttttaggaac gaacttagaa cttgcttggt
     1681 cgattggtat tgcttctatt gtgttaggct atttaaacgt tacgaaggct aatacttttt
     1741 tgagtttact aattaaccta cagggcaaga gcacaacggg taaaaccact acgttacact
     1801 ttattgcctc tttatttgga aatccaacta cggttcttag aaatatgaat gctaccaata
     1861 aagccattat aaagctagca tcaaacaatc agggaggtgt tccactaata ctagatgagt
     1921 taggagcagc aactcaaaat aactttagct cgttgatcta tcaattagct tcaggagaag
     1981 aaaggctaag attagattct aattgtcagc ttatgccaca agagactttt tctgttttga
     2041 cccttacctc ttctgaagag cgtttggaaa attatttcaa tgagaaatta actggtttga
     2101 aagttcgata tatcgaattt tctgatatca agtttacaaa ggatgcgaat cacgcagaga
     2161 aagttaaaag tctttcttct aatacttttg gttggggtat aaagttattt cttttgaaac
     2221 tctttgaaca agggattaca aaaattgaag caacttttgt cgaagctcaa aaaaaactat
     2281 gggctgtttt acctgaacat tctttgaagc aacgcattgg taataatcta gctttgattt
     2341 atagtggagc cctcctaatt caagatatac tgggctatcc tttacgatta gagcatatac
     2401 agacggtgct tattaattcg tacgaacagt taattgtaga tactagttta ggaagtgagc
     2461 aaacggtatt tgaccgagtg aaaacattgt tggtgatgaa tagccataaa tttttaacaa
     2521 acagtgacaa caaacatacg cccagtacga tttggggaaa agtatcaatt caaaaaaatg
     2581 gggatattaa ggtaaatatt tttcctatcc cgtttgagga cttgttaagg cgagaatttc
     2641 aagtaaagga tctaacctat ctttttaggc aattgcttga ttcgggtaat atgtgtgcag
     2701 aaaaagggag aagaacgaaa cgtattcaca tgaatcgtca agttcttcca acatacgaga
     2761 ttctattacc ttcttcactc aaatcgtatt ttcgattgta atttagaata aaccaaagta
     2821 tgaaagtgag gcaccatgtt atggaaatat ttcttattga tttagcaaaa caactgatta
     2881 cttatctgta tgatagcgag caaacccaaa cggaagtaaa tgaagcttga tctatgcttc
     2941 atttacttca ttcaatcaaa catgaaagaa aggaaaattc taatgactaa aaataaaatg
     3001 acactaaaag cagaggttct tctgtatatt caagaacatt tttcaaatca agcctttttt
     3061 acaaaaccaa tttacttgga tttcgaaata agaggggtat ctgctggatc tatcgggggt
     3121 actcttcaag cgttgaagaa cgaaggatat ttagaaaatc actttgtgca acgttcgttc
     3181 aatagaagag tcgtgaaaaa atggtattta gttcattcat agagagggga atcaagcatg
     3241 cgtgtggctt gttatgatcg aacgtctgtt tatgaagaag cgaaaattag taatgacgct
     3301 caatatgatg cagtgaaaga gtatgtttta gagaaatatg aacaaattcc ccaacgattt
     3361 tcagacaaag gagaatcagg ggaaaaagcg gagcgtccag cttttcgaca gcttagagct
     3421 tgggtttgtg cgtcagaaga agagggggtg atctatgttt ggcgttatga tcgattggca
     3481 cgtcaagcca aaatagcctt agaatttatt gagttgtgcc aacaacatca ggttcaagtg
     3541 tattcgattt ctgaacctct tcctgcttct ttctcacacg cgtcaacgaa taaactattt
     3601 gtgcaattat tgttcacttt tgcagaacaa caacgaaacg tcattattga gaatgttcgt
     3661 gccggacttt cctataaaaa gcaacaacgg caatatttgt cttctgcggt accatatggg
     3721 tatcgtttag tgaatgggaa aatccaacaa gaagtacacg aagcaaggat tgttcgctat
     3781 atttttcaac tttatttgac caaaaaatat ggctacaaaa agctttgtca acgattgacg
     3841 caacaaaagc ttttcttccg cgaacgtcct tttcagccct atcatattta tagtatccta
     3901 aaaaatccat tgtactatgg cgaaatcaaa ggaggatctt tggggaagta tctaggaacc
     3961 tttgaaccga ttctctcgaa agcaaccttt ttacaagccc aagagattcg ccaatcaagg
     4021 tgtacagcta aaaaagatac gtatctgtac ttattacgtc aaaaaattcg gtgtcccttc
     4081 tgtggtcgtc atctgagttc gaagtatcaa tggaatacaa agaagacgaa gacgcttcat
     4141 tattatcatt gtaccgaccg aagctgccaa ggaatttttc ttcgggcaga aagggttgag
     4201 tcagaagtat tggaaaagat acaggctttt tttcaatacg aaggcgtcta tcaagccttg
     4261 attgcccaat taacgcaaca attagccgaa aagcgaaaag atgaaaaacg caaagtaatc
     4321 caacaaaaga aacaagaagc acaatggatt aaggcatttg aagagggcaa ttgttcactg
     4381 gaagaactca agcaacaact gcaagctctt caaaagccga tgtctacttc ttcgtttctt
     4441 tcactccaac agtgtgaagc aaaagtgaaa gaatggcttc aactaaaaga cctctctagt
     4501 cgacaattat tatgtgacta tgtttgtcgg attgaggtaa caaaggataa aacagtttgt
     4561 gggatttact tccgacaact gacacaaaat attttagaaa ggaacgaatg atctatggaa
     4621 atgatacaaa ccaaacgagt cgcattgtat attcgcgtga gtacacaaga acaagcttta
     4681 gaaggacata gtattcaagc acaagaacaa aatggacgac agtttgccga acggatgggc
     4741 tatgaagtgg tagaagttta tgccgatgaa ggaatcagtg ggaaatccac aaaaaatcgg
     4801 ttcgcctatc aacgaatgat gaacgatgct cggaaccatc gttttgatct actagtgatt
     4861 tggaaattga cccgtctcgg acgcaatatg ttagatgtct tacaaacagt cgaggaatta
     4921 ttgcgatatg acgtaggatt acattcgatc tcggaacaat ttgacgtgac cacttcgaca
     4981 ggtaaattga tgttacaact ccttgggagt ttcggtgaat ttgaacgcaa ccaaattgcg
     5041 gagaatgttc aaatgtcaat gcaaagctta gtgaaagata aaaagcgtta tgcaggaggc
     5101 cgacgtttag gctatgtcag tggtattgac acgaatggtc aaaaacaatt ggtcattgaa
     5161 ccagaagagg cgaaaattgt tcgtctgatc tatgcaaaat atttaggcgg agcagggtat
     5221 cgagcgattg ccaatttttt gaatcgtcaa ggatatcaaa cagtcaaaaa gaatgctttt
     5281 tctaccacgg cagtcaaaga tatcttacgc aataaaattt atgcagggta tttagaatat
     5341 gcgcgctaca tcaattggga aaccaaacga cggaagggga agaatccgag accgatttta
     5401 gtgaaaggaa cccatgaacc gattatttcg gaagaagatt atcaaaaagt acaagaacgc
     5461 cttgctttag aaggaaaaca acccaaatgg aaccatacag gtgaaaatgt attgacaggc
     5521 ttgttacgtt gtccagaatg tggcgcaccg atggcagcga gtaatgtcac aaatacccta
     5581 aaggatggca caaagaaacg gattcgatat tattcttgtt cagtctttcg gaataaagga
     5641 gcaagtgtgt gtcatgccaa ttcgattcgt gccgaacaag cggaaacatt tgtcgccgac
     5701 cgattaaagg agatcgttca gctaccagaa gttcttcccc gattggtggc agcgttaaat
     5761 gaagaaatag tgcgacaaag ccaaccattg gaacaagaac tcgtggtgtt actggaacga
     5821 aaggaagaat tgaagactaa aattgaaaaa tgggaagctg ctttggaaga tagtcctgaa
     5881 ttgtttccga tgttaaaaga ccgcttagac gaattgactg aaaaacgacg acagttgcac
     5941 attcgagaaa atgaaatctt agggatcttt caacaaggag agccgattca agtcaaagat
     6001 gtccaacgga tattgactag tttggatcgt tttcttgccc agagtgagaa gaagcaaatc
     6061 aaagccttgt atcgtacctt tatagagaaa ataacctttg atcctaacca taaggagatg
     6121 ttggaaatta cgatgaaatt cacgcatgcc gtggtacaac aattgaatga gcaatatcaa
     6181 atagccgtat ccaaaacaaa ggatacggct atttttgtgt taaaaacacc ctttacgtta
     6241 acgatctagt ctaggttata tcaaacaacg ttagaggggc gctaacgctt ctctagcgat
     6301 ttgaaatcgt tagagaagta gttagggagg tccttatcat aaatagggat atttattaat
     6361 gaatatttga aatataattg tatataagaa ttaaaaagag tggggataga tatgaaaaag
     6421 atgggtaagt gtattttatg tgaaaaatac actgaactta ctaaagaaca tgtaccacct
     6481 aaaaaatcag ggaatactgg aggtaaaaag accagaactg gtaatttaga tgatttcctt
     6541 aagagcgatt ttacaaaagg tgattttccg aaggggatta aaaggaaacc tcaaggaaat
     6601 gtttattata
//
LOCUS       DADVXV010000112         6553 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.115, whole genome shotgun sequence.
ACCESSION   DADVXV010000112 DADVXV010000000
VERSION     DADVXV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6553
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.115"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(442..945)
                     /locus_tag="KB969_002584"
     CDS             complement(442..945)
                     /locus_tag="KB969_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBB6870505.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            1304..2329
                     /locus_tag="KB969_002585"
     CDS             1304..2329
                     /locus_tag="KB969_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBB6870506.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            2652..3530
                     /locus_tag="KB969_002586"
                     /pseudo
     CDS             2652..3530
                     /locus_tag="KB969_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
     gene            4006..4122
                     /locus_tag="KB969_002587"
     CDS             4006..4122
                     /locus_tag="KB969_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBB6870507.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            5050..5388
                     /locus_tag="KB969_002588"
     CDS             5050..5388
                     /locus_tag="KB969_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870508.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            5482..5712
                     /locus_tag="KB969_002589"
     CDS             5482..5712
                     /locus_tag="KB969_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870509.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            6112..6483
                     /locus_tag="KB969_002590"
     CDS             6112..6483
                     /locus_tag="KB969_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBB6870510.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
BASE COUNT         2233 a          964 c         1206 g         2150 t
ORIGIN      
        1 ctacttctaa aaactactgt ttttttcctt tgaaatgcct tcaaaaagta ggatcaggca
       61 gaatatactg gcagaatcaa ggagaaggga gcctaaataa ggagaaaaac catagaaaat
      121 ataaagtaat tacttataaa acaagctttt tatagaaaaa taatatacct gagtagggta
      181 taaattaaga cggaattcct ttctagattg agatattgac taggaagaat gttaagattt
      241 taagccttta agctaaaaaa aaaccctttt tgttaaataa ggggaatata gcctgtcagt
      301 ttcaaactgc aagtcgtcct gctgcaataa tatagtagat tagagatgaa aatagatttt
      361 tttaaaccaa tgactgaata aaaagaccgt catagataca cattggaatg tgtctattac
      421 ggtctttttt tacgaacgat tttattgaag acggacagtt cgggtcaaaa ataaaaaagc
      481 tacgatcaga aataagaata aaatgtatcc caaaataatg gctagacggt ctaacttatt
      541 tgtcgataga tgtttgttta gaagttgata ggcccataaa cctatcagtc ctcctgttgt
      601 attagttatc aaatcagtga tgtccgctac gccaataccg aataggaatt gaatcaattc
      661 tgccaagaag cttacaagga aaataatccc taatttttta gaaaaagaaa gtctcttgaa
      721 attgacattc aaaagcaccc caaaaggaaa aaagacaatc aagttataag tggtctcacg
      781 taataccgtc gtattttcaa aagaaaaagt agaaaaaggg acgagattga cattgctgta
      841 agaataagtg agaaattgtg gaagattaaa tgatagcttg aataaaatca accataatag
      901 aaagaataaa taaatcccta ataaaaattt tgatacatac cgcatagaca tctcctccat
      961 ttaaaaagta taccatcgaa aaccgctgaa aaatcataaa aaagtatgaa gtttaaggac
     1021 caacgtagtt atcgtacgaa aattagaagc ttttttttgt tgggaatccg gtttctttaa
     1081 caaagctaag atagcgagtt gcttggaaaa gttgctatct tttttctgtc aaaacgactc
     1141 ggaatgttcg ttttttgttc taatttctcc aagttgttta ctttttgata ctaagtttat
     1201 gaaaaatcaa gaaatagttg ttatactagg taatgctgac aaacgggatt ggcatttcat
     1261 cttggttcag ctttttttcc aattactagg aaggagggat agattgttca agacttattt
     1321 tcgtttcaat aaaatacaag ataatccttt tcgtatcatg aatctgatgc tacttatctt
     1381 tattgtatta tggttaggtt acataaatca tgattttttg atttcaagtt tttcatcatt
     1441 agggatcttt acttttttct attatcaaaa cataccgatg aaatatttgc tgaaacgtat
     1501 gtttctgatc ggttgcggac tgttggttgc tttcgttttg gggatcttat cgacttatgt
     1561 tttatggctt gaaccatttg ccgtagcttt ggttgctttt tccagcagat tcgtgttgcg
     1621 attattccat atttctaaac caggtggctt gttttttgcg atgctttctg ccatgggaac
     1681 gagcatgcag ctgccaatcg ctcaattacc gatcgtctca ctttattttt ttatgggtgt
     1741 cgtttttgcc ctgattgcgg cagtgattac aaaattactg gattcacggc ctgagcagac
     1801 aattgaaaaa gcaactttaa aagaaagatt tcacgaagag cctttagtga tcattgattc
     1861 tgttttctac agcgctgcct tatttctttc cgtttatgtc agtcacggct tgaatctgca
     1921 taatccttat tggttgacct tgtcatgtgc atcgattttg ctagcagaaa acttggatgc
     1981 gatgaagcat cgacaagtcc aatatctgat tggatcgatg ggtgggttat gtgtgtcggc
     2041 attcttgtca tttgtgccgt ttacgcagtt gcagaccatt tttctgatca cttttctata
     2101 tggaatcgca caatttctag ttgctagaaa ttatgcagtt gctaatattt ttcttaatcc
     2161 gatggcgttg atgctatcta cacttattcg tggagcatac ttgatttctt tgatcgaata
     2221 tcgtttttta gggatcgtca taggaagttt catcggttta ggtgttgcgt gggtaatgac
     2281 ggttggtttg caacattatt taacggttgt tcgtcaaaaa ttagaataga aggacaaata
     2341 tatgtgccaa aagaggttat gacaagattt ttgtcacaac ctctaattca aggtgttcaa
     2401 aagccagatt ctcagcatta agtcaaattc acacaaaaat gtggaaagga actttcaaaa
     2461 aaattttata tttattctat caaaaaattt tgtttatgat ggtaactgaa taaactttcc
     2521 tgagatggtc aatgctttcc ttgaaagtct tacagatatt ctttcttcat agaaagttta
     2581 agttttatag ttagtgtaca ataaaagtat gtttatacca tatggtgtcc ggataatcag
     2641 tcatttaaac aatgaggttc aaagatatga aaaggggaaa tttgatgaag aaaataagca
     2701 atgaaatcca aattctggca gaaactttaa ctcttcccaa agtcgttata gagcaaatga
     2761 ttgtacaagc aaaaaacatc cttgatgagg tgtttgagca atatagtcat gaactaatgg
     2821 atcctaataa agcaaaggcg actgcaaaga aaatagacaa agtctatgaa gaggaacctt
     2881 ttgcagcatt agctatttat ctatatgcag cttctcaaag ttggaaaaaa atttatcaac
     2941 cattgaagat tccaagaact atctatttgg caacaatgaa tgcttttact agatttattc
     3001 atgaacattt ccaagtaaca ggaagctatc gctttgaccg tggtttttgg atttggcatt
     3061 acactagtgg cttgatcttt cggattggtg aattggagta cgaaatgaca tattttccga
     3121 aagggtacac ggatctaaga ttagaaggaa agcagtgcct ttctcttcat attccttccg
     3181 atgcagattt atctcagaat aagataagag atagttacga aagtgccatt cgtttttttg
     3241 aactttattt tcctgattac cattaccaag tgatgtacac agatacttgg ttactatcac
     3301 ccaatcttac taaatagttg aaaaaagagt caaaaatctg tctttttgca gccgattatc
     3361 gattattatc agttgatgaa caggacgata gtggagtccc ttggatcttt ggacgagtag
     3421 atgcccaaat acatgattat ccagaaagta cgagtttaca gcgacaagca aaagagcaat
     3481 tgcttgcagg cgagcacatt ggctctggct taggtattct tacttcataa gtttagtact
     3541 tcgaaatagt ttaaaagagc gtgagacaaa agtaaagaac acttttgtct cacgctctaa
     3601 acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa attcacaaaa
     3661 atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg cttctgtccc
     3721 agcctctttt ttagtgttct atcgaacaca cagtacgttc aataggtaaa ctagctataa
     3781 caatagatat taaagttaac ggacaagagg gcctttttta ggtagctaaa acgtaataat
     3841 gaaaatttat ttccagagat aggagtcaat cagctagtct gatcgactgt tttaacaagt
     3901 tgactttcat tttaactttt gataccattt aaaacacaaa tcgtaattgt ttcgatttgt
     3961 gttttttagc atgactacaa tcaaagaaga aagtgggtcg tccatatgga aaaaacagat
     4021 atctcaagtg cataccgccg cttgaaaagc ccaaatatca aaacacgaaa acgtgcgctg
     4081 aagatcatca aagatgtgaa acggaatagt gggaaaaggt aagaagaagg aaacttaatt
     4141 aaaaaaatag ccgaaaaacg tttttcggct attttcaata atcggttttt gtgtaaggtt
     4201 tccgaaagaa ctgctgttga ttttccattt ttaacatatg ataaattggt agaatctttc
     4261 ttttcaaatt gataccattc cctaattcca gttatatagt taactacaga accacaaagc
     4321 acgtacgttt ataaaagtat tatctgtagt tatttttcaa ttccctttca acctcttatt
     4381 ttgaccagta gtattgatca ctttaccttt taacaccttt gttcgttttt gaaacatttt
     4441 tagtcaagaa tggaaacgta actacataat caaaggtttt gcgaaatatt tcatgaaata
     4501 tttcatgtag aagcgagcaa tacggttgca aataaccatt atcgtttaat aagcagttac
     4561 gaaagctccc aatatctcta acgttcagct cactccattt cttttcttca aaaaaatcag
     4621 tgattcgtat ctctttctat ttgtcgaaaa agttaacttt aaaaagtaac gccgaaaaaa
     4681 tatgcaaaaa aataaaaaag cagttactat tgctagaata acatcaagga ataataagtt
     4741 ttggttttca gataatagtc gataagttgt gtattggaat tttagataca gtaataaagt
     4801 atttttcatg aaattttgtg agaatcacta ttacaagtat ctttaataaa attaatggtt
     4861 aaggaggaac ttaaagtaga atgtaaatga atagttgtag tcagtcgatt gtgatactag
     4921 actcaaagtt gcaggaataa gtttttcaat ttgtgattgg aagataaaaa atgaaaaaga
     4981 agggcttttt tttatacttt gttgattgta gtgtttattt tccctctgtt tagccaagta
     5041 acattttcta tgactcaacc agtttcaagt gaggaacatg ataacctttt tcgtgctaca
     5101 gaagagttta agaaatatca ggaaaatatt gttccggaga ctccattagc tagtgagcca
     5161 attactgata ttgatggaaa ccaaatagga tggtatatac agtacgaagt tatggtggta
     5221 aataatgact caatagtaaa aaatacagta ggcttagagc taacaccgat tgaaaaggtg
     5281 agttcattgt taacgtatat ttatactgat gaaagtgacg agactgagat cattttaacg
     5341 gattactcaa aaattgctac tgataaaaag tatatattgt ggatgtagac actagtgaaa
     5401 tactttatga tatagaaatt gatgaaaatt tactagatgt agcacaagaa atcgatcatc
     5461 aaaagcagga agctattcga tatgctggta gaaaagggaa aagaaaatat ttattacgtg
     5521 aatgtagcaa aagttagaga agatgaaaat gagtggaaag aattcaagag tcgctactca
     5581 attaactcga ctccgacatt tacagtttac agagaaggat cgatagaaaa aactgttttt
     5641 tggactaaag aaagtggaat gtctttagct gaagtagaag agtttttgga ttatgttagt
     5701 atgcaacagt aagggagttc ttattatgaa aaattttgac acatattatg ttattgtttt
     5761 ttcgatatct ttgctgttaa tattactaac tttaatgcag tataaagagt atccagagta
     5821 ttttatttta acttttgtat atttagtaag tagctacaca cttctatata aattcagaag
     5881 ttcttctaga gtttctaaag tttgtttctt aattagctta ttgattctat aatatttttg
     5941 atttatatag gaaattaaaa atattataga atcaacactc agagaacggg ttggttttta
     6001 atagatttaa taagtactga taatgaaatt tctcctggtt gggaaaacga agttggttac
     6061 cctgtagaag aattttttca agattacttt gcggagtatg ccgataggat aatgagagat
     6121 tacgtaacag ataaaactca agaagtcatc aatcaatccc agtcattaaa tgaattatct
     6181 gataaggcga aagaagaagc agttgccatt atttcttcag ggattagtga ctatattgat
     6241 atgagtggtg aaatcaatta tggcgataaa gacaaaattg tacgcatgat aaaagctttt
     6301 atcaaaactt ttgatgtgaa ggcagatctt aagtttaatg atacttacct agtaggaaaa
     6361 ttaattaata tccttgggac agagaaagat acggaaacgt ttatttcctc tttgtctatg
     6421 ttgtttacag ataagcattt ttcaactcag cttggtggag aggaactagt ggaaatcttt
     6481 taaccattac gcccagcatt aataaaagta tatcaaaaaa gtactcctga tgatttttaa
     6541 gattggtttg aga
//
LOCUS       DADVXV010000113         6440 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.116, whole genome shotgun sequence.
ACCESSION   DADVXV010000113 DADVXV010000000
VERSION     DADVXV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.116"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(173..1084)
                     /locus_tag="KB969_002591"
     CDS             complement(173..1084)
                     /locus_tag="KB969_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBB6870511.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(1541..1969)
                     /locus_tag="KB969_002592"
     CDS             complement(1541..1969)
                     /locus_tag="KB969_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870512.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(1997..2635)
                     /locus_tag="KB969_002593"
     CDS             complement(1997..2635)
                     /locus_tag="KB969_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870513.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(2639..4621)
                     /locus_tag="KB969_002594"
     CDS             complement(2639..4621)
                     /locus_tag="KB969_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBB6870514.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4801..5466
                     /locus_tag="KB969_002595"
     CDS             4801..5466
                     /locus_tag="KB969_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870515.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT         2064 a         1179 c          978 g         2219 t
ORIGIN      
        1 aagattatac agaaaaatat ctagggtcgc tggattctaa gtaaaaaaaa tttttaaaat
       61 aaaaagaact aaatcaagta gtaattaaac tactgttgat ttagttctaa taaaaagatt
      121 tagatgaaca gttttattga tttaaatagt tcatattttt tatttatacc gcttatttac
      181 tacttgctgt actagaatct gaagtgaatg tactcaaaac attttcaaag tctttgtctt
      241 tgatttttac attagcgtct ttcaatactt cgccaattac tttattctgg aaggtactgt
      301 cacttaattt tgtgtctgtt gcaatttctt tcaattcttt tttgtattta tccatgtcgt
      361 tgcctttgtt ttggtttttc accattttaa ccacataata ttccgtagta taagttgaag
      421 cattggtaga agtgatcaca tcagaaactt gaccatcttt caacttaaag gctgcttctt
      481 tgacttctgc cggaaccgtt gtagtagtgg aatcaaattt cacttttccg ccatcttctt
      541 ttgtcgtagt atcagttgac ttgtctttgg ctaatttaga gaaatcgtct cccttatcag
      601 cagctttctt cacatctttt gcatcatctt cacttgctac ttggataatt tgagcttcca
      661 cttctggatg gaaagattcc caagccgttt ttaaatcttc atcggtcaat ttgatatgtt
      721 tctttagacc ttcttgaaag gctagacttt gtttgatact gtctttgaat gtttgttctg
      781 tgtaacctgc agatttcaat tgtgaatcaa atgaatcacc caattgtttc tttgtttgat
      841 catattgaga atcgatttct ttggttgata cgtcatctcc atatttatct tcaaatactt
      901 gataaacgat caactgttgc acagcggaat ctgctccttg catttttttc aagctatcca
      961 ttacttcttg ttcgctgatt gtaccgcctt tataactaac ggctgttttt tcaccggcat
     1021 tcgtacagcc tgacaataag ccagtgccta gtacgatggc aagtgctaaa aatctttttt
     1081 tcatttatca attctcctac ttttcgtttt ttgcgaattg ctaaaaacaa aggtgttcaa
     1141 gatgaaaatc atcaagaaca cctttactaa tctgctcgat acgtcctgaa tagatataag
     1201 gctacacaat ccagaaagtt cgctcagcag aataaatgtc aagtagcaca tcacacctta
     1261 atatactact tcttttgtta ccgtttttca agtctatctt gcgttccgta tttaacgtaa
     1321 ctaattctta gaacaaatgt tatcgatttt gtttttcttc ttccgctgct gggatattca
     1381 aatcagacac ttttatgttc gattttccag acattttttt gttgttttta ttatgatata
     1441 tttttataca actaaaaatg aatatattaa aactaccaaa aataactttt aacgctgttt
     1501 cattatatgt tttttctatt ttatataaac ttttggatac ttaataccaa ccggttggat
     1561 tgtaccaaca tgagaatgtg tcagttctat ttcctgtcgc acttgcatag gcccatactc
     1621 cttttgttgc atttgctgat cgaatagagt ttccaacttt cgcttttgca ccgtgacgat
     1681 tatagacacg actatagtgg ttagaatgac ctgtttttct cgtacaagtt gtatcactat
     1741 aataaaccca tcttccagag ctatgattaa ttgctgttct agaaatttcc cggtctactg
     1801 gtaaatttga cttaataata ttacctttag catcaaaatg aatctctcct ggctttaaag
     1861 atttgtaata gatttcaccg tgaactgaat ttgcttccac ttcagatgac atagcgtttc
     1921 ctccaacaaa acctatccct agtgcacaaa taataactgc ttttttcata aaacgacatc
     1981 ctttcctttt tgatttttaa agcatgatct tcttgtttcc tattttggtc agatatggat
     2041 catgcgtgac tacgataact aacgtacctt gggaagcttg ttgcgataag atttcaacta
     2101 ctttatcctt atttctttta tccaatgacc cagtcggttc atcggctaaa atgattttgc
     2161 tattcttcaa taagactctc gcacaggcga ttctttgctt ctcaccacca gataatgtgt
     2221 agataggcgt acttagcttc ttgtttatat ttactttttt caatgcctca tactttgctg
     2281 ttcgcttatc tgaaacattt aaattcgaaa acttcaatcc aatatctaaa ttaaaatcga
     2341 ttgtttcata ttcaatcaac ccaaaatctt gaaaaagaaa agatatggta tttcttttta
     2401 tcaagcgctt ctctctccca gttaattgtt tcgtctcttg atcgaacaaa tagaattgtc
     2461 ctgaactgaa ctgatcattc aatcctaata tattcaataa cgtactttta cctgctccac
     2521 tttctccaac aacagtcaca agatccccag catccgcagt gaaacgatcc aaatgaagaa
     2581 tcgttttgtt tcgaatgatt tttttcgcac cttttatcac tatcaacggc tccaattgtt
     2641 aacctccatt catcagcaat aactgacttt tcttttctgt agacaaaata aaaacaactg
     2701 aaagaataaa atcaatgaag ctaaagaaaa aaatattaaa aagatattta ggctctcttt
     2761 ctataagaaa aaggaagatt acacttgtcg ttccccattt gatgaggttc atcatgaaga
     2821 aatctttata cgtttcaaag agcgaataac cacttgaacg aaagatagcg attttccgac
     2881 aattgtagac aaaatatatg cataacatga catagctcaa caagaagaaa gaaaagaaag
     2941 tgagtaaaaa tatctgtatc aagtaatgaa atgatctgct taacactttg acagctatct
     3001 cttcagtctg agtatacgga aatgataact gcaagttatc acgtaactga ctttcttcaa
     3061 tcagctcaaa taacctttct ttcgacaaag agcctatctt gatctttaac ggtggataga
     3121 tttctccgct gagaatattt ctttccaaat acatactgtt tttcaatgtc agtatttcaa
     3181 caaccggata atgttcgatc caggggatag aaggaataaa tgtataaatg ggttgattgt
     3241 tttttataaa tagaaatttc ggttcttttt cactgatttc ttgataatat tctgttattt
     3301 gcgccaggtc attttttaaa tctgtatgtc tatatcgttc agggatcaat ataacagggt
     3361 gcgtttcttt ttcggttatt tggatcaacc ttccagagac atcaatcaaa ggaaatttct
     3421 taagataatt cagatttatt tttatccctc tgccaaactg ttcattttct tcattcaagt
     3481 aatctgatac attgactaat atacttccgt ttttattcaa agtttcatat aattcctgat
     3541 ctgctgctga tgcaaaacga ttggaataaa taaaatccac gtggtttttc ccgatggtta
     3601 ctggataaaa tacatgatag tcctcaccag cgatttcttt tggtggttca tgggaaacag
     3661 ctaactgtga agaagaaaaa acgatagttg ctaattcgac attggcaacg gtcaaaagaa
     3721 gagaaaacaa caatccaaat gtaaaaagaa tgtattggat atagttgaac gcttctctta
     3781 acgaagcgat tttttcaact aataaaagag aaatcaaaga gataccatat attccgctga
     3841 acaagaaaac gtacatctgg aacaaataaa gaaattgctc cttataatac ataaaaataa
     3901 aaccaccaat gattcctgca attatgaatg taataatgat tttctttttc cccaataaac
     3961 accacaatac ttgatgtaat gaaaagtcat tattcaacaa taaactgatt tctttattca
     4021 tcaataagaa aaaggatgat aacaaaagga ataaaagaat caatccaata gttaaataca
     4081 ctcgataatt atatacgtct gtatttgaaa taaccgaata cgaatagcta ttttcaaagt
     4141 cttcaaaaat attagtggca taatcagtgt gaaatgcttg attgaatcga tcagtgaata
     4201 gtgaaatgaa ccgttcatag gcttcttttt ctctcgtcat caagaaaaat tcaccttcaa
     4261 aatcttttat tttgatcgat tcttcaatgg acgttacgcg aaaggaggta ttagaatagg
     4321 gtaccttctc gtgagaagat ttgacatccc cttgataata caatgtcatt tcaagctttg
     4381 gctgtatctt gaagttccaa gatgtatcta cttcattgga ttcatttact gtttttttca
     4441 tataagaaag ctcagtttct gatgagacat tttcaaatac catgattagc tgctcatatt
     4501 cttcttgccc aataaaatgt tgtggcaatc gaatcggagt ataagtatct gtttgatgga
     4561 aaaattcatt tgtccgatag agtacctgtt tatttatact aaccaaggca aaaccactca
     4621 tgataccggt cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt atcaccactc
     4681 tcccttactt aaatgattct ttgataaaat cataccgttt ttcatcaaaa aaacgtatct
     4741 atcaagtgta taggtcatgt agaataaatc tatatactgt agaatcgaaa ggagaagaag
     4801 atgaacaccg gagaaaaaat acgaacttac cgcagaaatt gtaagcttac gcaaaaagaa
     4861 ttaggcgaaa aaattggtgt ttccgataaa acgatttcta gttgggaaaa ttctcgtaca
     4921 atgccagacc ttgaaatgct gtcactttta catcatactt taggtctgcc gattgatttt
     4981 ccttctattg aatcagctac cgaatcaata gaaccaacat tgccagatga acctcttgtt
     5041 aacaagaaat cttattcatc aaaacaaccc ttctcactca aaaagacact atctttcttt
     5101 ctgctcgtct tttgtttggt ctatcttttt cttatcaatt atcaatacaa aaatgaaacg
     5161 atcgatcgat tcaatccttt tttgaaacca caaatcggct ataccacact ccctgtagga
     5221 tacgtggaca attccatcga acgttgggta tgtaatgata tctttggcca tggtacatgg
     5281 ctgtcttttc acgctggaga ggtagaaaaa gagaaaaacc atgctgtaat caaacacaaa
     5341 ggaaaacacg tcatgaacgt tcgcctgctc acttgggaag ccattccctc agattaccaa
     5401 gaaatcctca gccaagacta tgacgacgcc ttaaaaagaa gccctcagga gccagatagg
     5461 cattaagtag gagatgaacg tagagataga aaaaatcaat gcacatgatc ttatccaaaa
     5521 aacaggggta caaattaatt gaaaaagcct tgagatgaaa gttcctaaat aaaaaagttc
     5581 agaatgatag gtatttctgg cttatagtat aatatttacg ccacagcctc ccaatgattc
     5641 tttttggaat cataatcaag gatggacatt cacaaaaata ttttgctcat tcgatccgaa
     5701 tagattaacg accaatctag taagtaatat agattggtac gtagtcaagc tgcacataat
     5761 ttagatcaat tttagttctt ttttatattt ctatgatctg ctcatttact tttatatgat
     5821 ggcttacagt aacataaata aatatgataa tcgctggtag tttatccaag agtactcaat
     5881 aaaatacaaa atggattgtt caagcgccta tcataatgat aaaatgaaac aaataaacga
     5941 tacaaggagg aagagacttt gagtaatggc agaacaattt tttcattgta aaaattgttc
     6001 agttgttaat ctatgggatt tcggtagcat gggcattttt ttatagagga atcacaccaa
     6061 cctggccgtt ttatctcttg ttagtgggaa tattagtagg aaattttgcc cctcttcact
     6121 atcgtacgaa cttttttcca actgattctg gcctttttct taaaacaaag acgcgaaaat
     6181 tagaaaacat tattgaaatg acaattacct gtataatcat tttcttagtt atattcctaa
     6241 acgtcttcta ataagaatct cttaaaatta gcttgttaca gttagttacc tagtttatat
     6301 aacacagtta tcttatcttc cttatcaaca tcttttgcca actctttgtc ttaaattcga
     6361 aacatataag cagagctacg aacaccaaga ctgtttcggc tctgtttttt gcatcaaatt
     6421 cactcttata tagctgataa
//
LOCUS       DADVXV010000114         6406 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.117, whole genome shotgun sequence.
ACCESSION   DADVXV010000114 DADVXV010000000
VERSION     DADVXV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.117"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(99..1229)
                     /locus_tag="KB969_002596"
     CDS             complement(99..1229)
                     /locus_tag="KB969_002596"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBB6870516.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="KB969_002597"
     CDS             complement(1878..3080)
                     /locus_tag="KB969_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6870517.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="KB969_002598"
     CDS             complement(3140..3343)
                     /locus_tag="KB969_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBB6870518.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="KB969_002599"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="KB969_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="KB969_002600"
     CDS             4880..5692
                     /locus_tag="KB969_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870519.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1919 a         1311 c         1007 g         2169 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgcct
//
LOCUS       DADVXV010000115         6348 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.118, whole genome shotgun sequence.
ACCESSION   DADVXV010000115 DADVXV010000000
VERSION     DADVXV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.118"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..324
                     /locus_tag="KB969_002601"
     CDS             <1..324
                     /locus_tag="KB969_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870520.1"
                     /translation="KHEAKIGSQWVNLPYKTTGSSIIYRVTNEKSQVITLPVYAYLGT
                     NVEINHQPVKEQVNANGLVQISGVKGVADIKVSTSYTVTTIISYLVTLTAYLCLFFKI
                     VFHKR"
     gene            499..1332
                     /gene="msrA"
                     /locus_tag="KB969_002602"
     CDS             499..1332
                     /gene="msrA"
                     /locus_tag="KB969_002602"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBB6870521.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            1445..2401
                     /locus_tag="KB969_002603"
     CDS             1445..2401
                     /locus_tag="KB969_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBB6870522.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            2690..3388
                     /locus_tag="KB969_002604"
     CDS             2690..3388
                     /locus_tag="KB969_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBB6870523.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            3538..4854
                     /locus_tag="KB969_002605"
     CDS             3538..4854
                     /locus_tag="KB969_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6870524.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            4871..6286
                     /locus_tag="KB969_002606"
     CDS             4871..6286
                     /locus_tag="KB969_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBB6870525.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
BASE COUNT         2148 a         1003 c         1339 g         1858 t
ORIGIN      
        1 aaacacgaag caaagattgg cagtcaatgg gtaaaccttc cttataaaac aactggtagt
       61 tctatcatat atagagtaac taatgagaag agccaagtaa tcacacttcc tgtatatgct
      121 tatttaggaa cgaatgtaga aataaatcat caacctgtaa aggagcaggt gaatgctaat
      181 ggattggtac aaataagcgg agtcaaagga gttgctgata ttaaagtaag cacaagttat
      241 acagtaacga ctattatttc ttatcttgtt acattaactg catatttatg tttatttttt
      301 aaaatagttt tccataaaag gtaaattaac ttttcattta taaaataaat tgattaaaaa
      361 ggagaatctg tcgataagga ttctctcttt tttatacgaa aaatctgtag ggggatgaag
      421 taatcgctta tttcctcact ttatgataaa ttacagctaa agtcactagc ttgtcttctt
      481 cggaaaggag gagaatctat ggatgaggaa caaatattca ttcaaacact ttataatctg
      541 attttgaatc cgaatacacg agattgggaa cgaaaagtat tgattcagac aaagaatgac
      601 ataagagaaa atatatccgt taaagaacag ttatcaaaac tagaagcaac actacgtcca
      661 ttagctatcc gaatgaatct gacgcctgat gtaatggact tttatttatt gattacggaa
      721 ggatttgata aggagcaaaa atatgacttt tccaagcatg ccatgcaaga tgctgactat
      781 caagaacgtg cagtatttgc agggggatgt ttctggtgta tggtcgagcc gtttgaatcg
      841 aaaaaaggga tcctatctgt tttgtcagga tacacgggcg gacatgttga aaaaccaaat
      901 tatgatcaag taagtggtgg ttacacaggt catgtggaag ctgtggagat catttatgac
      961 acaagagaaa taagttatag cgagttgctg acaatctatt ggcaaattac tgatcccaca
     1021 gatacatttg gacaatttca agatagaggg aagcaatatc gtccagtgat tttttatcaa
     1081 gtcgaacgac aaaaagaatt agcggaacaa tcaaaacaga aactagacag ttcaggaact
     1141 ttccaccaac caatcgtcac aaaaatcgaa ccagccggta cgttttggcc agcagaaaac
     1201 tatcatcagc aattttacaa aaaacaaccg aaacgttata aaaaaatcca gcaagcacgt
     1261 aatcaatttc tgatctatca acgagtaaaa aacaaatggc aaaaaaatat acgaaaaaat
     1321 cattttgatt aactcctttt ctttaaaatg tagtaaacta aaaatagaaa aaagaaagcg
     1381 ttttaaaaag atttgatgag gaggagaaaa attgtatatt gcagatagtg cacgttatga
     1441 aaaaatggaa tatcgtaaat ccggtcattc aggtttgaaa ttaccgattt tatctctcgg
     1501 attatggcaa aattttggtg attatgatcc tatccataat caaagagaga ttttaagagg
     1561 cgcattcgac atgggaatta cccatttcga ccttgcgaat aattatggag gccctgctgg
     1621 agctgcagag aaaaactttg ggcgtatttt tagagaagat tttcaagcct accgtgatga
     1681 actgattatt tctagcaaag caggttatca tatgtgggaa gggccatatg gggaatgggg
     1741 ctctcgtaaa tccatcattt caagttgtga ccaaagtctc caaagaatgg ggctagatta
     1801 tgttgacatc ttctatcatc atcgcccaga ccctgataca cctttggaag aaacagcaga
     1861 agctttgatg caacttgtaa gacaaggaaa agcattatat attggtatat ccaactataa
     1921 tggagaagat acaaaaaaaa tgactgaaat tttaaaaaga aaggaagcac cgttcattat
     1981 tcatcagatg cgctacaata tgttttctcg tgcactacta gaagacgatc tatctccagt
     2041 attagaagaa gaagggctag gggcaatcac gttcagtccg cttgctcaag ggttgctgac
     2101 aaatcgttat ctacatggta ttcctgaaga ttctagagca catcgtaagg aaataccatt
     2161 cctttcagaa gaacaagttg gatcaactct ggaaaaaatc aaagcactgc aaacaatcgc
     2221 cgtatcacga ggacaatcat tagcgcaaat ggcccttgca tggaatttgc gacaaaaatc
     2281 tgttacaagt gtactggtcg gagcaagtcg gttaagtcag ttacaagaaa gtgttcgaat
     2341 gatggataat ttagatttct caccagaaga agaattgaga atcgaccaaa ttctagaata
     2401 gaaacgatgt aatcaaactt tttatccata tattaaaaaa aacaaaagat gacatcaaga
     2461 atcgaatgaa gatcgtctgt tattgaacat catatttttt gtcgttcaaa ataaaaatga
     2521 tcgaaggcta ggagtgaatt ttatcctagt cttttttatg gtaaatatct tcttcgtttg
     2581 tatgtctatg aacggattaa tcaattttgt atacaaaaaa tcatcagatg attcaaacgt
     2641 gttataataa ttacgaaaaa atacatcaga tgaaaaggag gtatgtggtt tggaagaaaa
     2701 taaaacccta gtagaagtaa ctactgacaa gatccttaga tatttaaagg aaatgcagtt
     2761 gcaagtagga gataaactgc cgaatgaata tgaattgtcc gattatttag aggtggggcg
     2821 aagcacggtg cgagaagctg tgcgggctct agcttccagg aatatccttg aagttcggca
     2881 aggagcgggg acatttgtca gtgataagcg agggattgcc aatgacccac tcggtttttc
     2941 tttgattgaa gatcaggatc ggatgatacg agacttattt gaactgagat atttattgga
     3001 gcctaagatg gcaggtttgg cagcggaata tgcaacgaag aatcaaatcg tccaaatgaa
     3061 aaaattaacg caaaagattg aaacttcttt tcgagaaggc acacaagaac atgttcaatt
     3121 agacatcgat tttcatacga tgattgcaga agctagcgga aacgtagcct tgctgcatat
     3181 tatcccaatc attaatgaat caattgcttt gtttaataaa aattatgata tccagcatct
     3241 gaaaatcgag acgatcgata ttcatacaga gatcgttcag gccatcgaaa ggcggaatgc
     3301 acttgctgcg tttgatgcaa tgactgtcca tatggcaata aatcggagag aattacagaa
     3361 aataatagga gaaaaagaaa ctaattgaca gttcatctga tgtattttat gataaataca
     3421 tcagatgaat ttttgtttta tatttggtaa aaaagaggag taaatagttt ctgttcatcg
     3481 aaatgtaagc gctgactaat agacaaaaag agatgacgtc aaggagaaga agcaggaatg
     3541 aggggatctg gaatgagttt tatggataaa ttagccaatg ttttagggaa cgtggcaacg
     3601 agaatcaata atttaaggta tatcatggtg ataaaaaacg catttgctgc attgattccg
     3661 gtaattatta cgggtgcttt tggcacattg ttttcagcaa tggtctttga ctcggaaaat
     3721 ggcttagcac agataagttt cttgcgtttt ttagaagaat taaagcctat cgcatctgcc
     3781 atcagctatg tcacactaag tttcttgacc atctatgctg tttttctgat agggatcgaa
     3841 ttagccaagc tgaataaagt ggatggtgta ttccctggta tcatcgcagt gatgtcttat
     3901 ttatctgtta atccaactgt ttatgaatta gtgaatgaaa atcagactgt tatagtagaa
     3961 aacgtattgg ctaaacaata tacagatacg aaagggttat ttttgggaat gttggtctcc
     4021 atcctttcta ttgaacttta ttgctggttg aggaaacaga agaaactaca gctgagaatg
     4081 cctgataccg tgccaacgaa tgtttctgct agtttttctg ctttattccc gacgattctg
     4141 actgtatcgg gtatcgcggc tgcgggattt atcatcaaag aacttacagg aatgtacctt
     4201 tatgatatca tttacaatgt cgtacaacgc ccattagaag gtgtcgtaca agggttaccg
     4261 ggtattttgc tattgatgtt tattgcgcaa gtcttttggg tgattggtat ccatggaaat
     4321 caaatggtga agccgatacg ggaaccgttg cttttagcgg caattgctgt aaatacggaa
     4381 gcttttgaag ctggaaaaga agtaccgaac attattacta tgccattttg ggatatgtat
     4441 atgagtatgg gcgggtctgg agtcacgatc ggtttactga ttgcagtatt gttagttgga
     4501 aaacgggaag atatgaaaca aatcaccaag ttatcccttg ctcctgggat cttcaacatc
     4561 aatgaaccag ttatttttgg tatgccgatc atgctgaatc caattttagc tattccgttt
     4621 atcttaacgc ctcttatcac tggaacgatt ggttattttg caaccgcttt aggatttgcg
     4681 gcgaaagcag ttgtaatggt cccttggcca atgccgccga tcgtcaatgc ttatctggca
     4741 acagcaggaa atatcggtgc agttattacg caacttgttt gtattattgt ttctattttg
     4801 atctatctgc catttgtaaa agtagcaaat cgtgtggaaa atgatgggat ctaaaaaaca
     4861 ggaggaaatc atgaaaatta ctattccaaa aaattttatt cttggtgctg catcttctgc
     4921 ttggcaaacg gaaggttgga aaggaaaaaa agaaggacag gattcgttta tagatagctg
     4981 gtataaaaat gaacattttg tttggcataa tgggtatggc ccagccgtag caactaattt
     5041 tatggaacaa taccagcagg atgtggatct gatgaaatcc atccatctga cacattatcg
     5101 gacttctatc aattgggctc gtttttttac tgattatgag aactgtatag tagatgaaga
     5161 atatgctcag catataagtg aaatgatcga ctctttgatc gaagcagacg tagaaccgat
     5221 gatttgtttg gaacattatg aagtcccagc ttttcttttg gaaaaatatg atggctggtc
     5281 ttcaagaaaa gtagttgatt tttatgctaa gtatgctcaa attgcctttg atcgttacgg
     5341 tgatagggta aaaaactggt ttacattcaa cgaaccaatc gttccccaaa cgcgttgcta
     5401 tttggatgct gttcgctggc cgcatgaaca aaacacaaaa aagtggatga tgtggaatta
     5461 tcataaagtt ttagcaacgg ctaaagcagt agagatttac cgcagcggaa attatggtgg
     5521 aaggattggc tgtattttaa atcctgaaat ggtctatgct cgatccaatt ctccagaaga
     5581 ccaaaaagct gcttatatgt atgatttgtt ttataatcga gtattttttg atccgatggt
     5641 aaaaggatac tacacagaag agttcctgga gttgtgtcaa aaacaatcga tttatttcga
     5701 tcctgcaaca gaggatttag aaacgattca gcatcataca gtagatttcc ttggaatcaa
     5761 tcaatattat cctaaacgcg ttcgcgcccc tcgttatcaa tggaatgaag agacaccttt
     5821 ccatcctgaa cgatattatg aagtctttga tttacctggg aagaaaatga ataattccag
     5881 gggatgggaa atctatccga aaatcatgta tgatatagcc atgtatctaa aagaaaatta
     5941 tcataatatc ccttggctga taacagaaaa cggtatggga agagaatatg aagaacagta
     6001 tatggatgag aaaggaatcg tgcaagatga ttaccgtatc gaatttatcg gacagcattt
     6061 gcattacttg atcaaagcaa cagaagaagg cgcaaattgc gaaggctata tgttatgggc
     6121 attcactgac tgtgtgtcac caatgaatgc atttaagaat cgatatggat tagttcgaat
     6181 cgaattgaac gatgaacgaa gcagaacatt gaaaaaatct gcttcgtggt atcagacttt
     6241 gattgataag agagaattgg atttgcctga cgaaatctat aaataaatag aagttttttg
     6301 tagatgttca ttgtatttac tggttatttg aaataaaaga ggttgtga
//
LOCUS       DADVXV010000116         6319 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.119, whole genome shotgun sequence.
ACCESSION   DADVXV010000116 DADVXV010000000
VERSION     DADVXV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.119"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..326)
                     /locus_tag="KB969_002607"
     CDS             complement(<1..326)
                     /locus_tag="KB969_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HBB6870526.1"
                     /translation="MNAFKTALNNNEMEGKIIGADCSELAPALYMCDEKIVLPKVSES
                     NYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVVLVSSEKVIDICENK
                     ILTSAF"
     gene            complement(380..2197)
                     /locus_tag="KB969_002608"
     CDS             complement(380..2197)
                     /locus_tag="KB969_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6870527.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            complement(2211..2975)
                     /locus_tag="KB969_002609"
     CDS             complement(2211..2975)
                     /locus_tag="KB969_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBB6870528.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            complement(3003..3701)
                     /locus_tag="KB969_002610"
     CDS             complement(3003..3701)
                     /locus_tag="KB969_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBB6870529.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(3713..4492)
                     /locus_tag="KB969_002611"
     CDS             complement(3713..4492)
                     /locus_tag="KB969_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBB6870530.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(4508..5452)
                     /locus_tag="KB969_002612"
     CDS             complement(4508..5452)
                     /locus_tag="KB969_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBB6870531.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(5498..6277)
                     /locus_tag="KB969_002613"
     CDS             complement(5498..6277)
                     /locus_tag="KB969_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870532.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
BASE COUNT         1653 a         1309 c         1139 g         2218 t
ORIGIN      
        1 aaaaaagcag aagttaaaat tttgttctca caaatgtcga tgactttttc tgaagaaact
       61 aatacaactg agtctgtttc attttcaata tattttttat ttcttgataa tgttgataat
      121 tcagtatcaa tagtaggaac aattaattta atttcaaaaa actttattac ttttattaat
      181 tcctcaatat aattactttc tgaaacttta ggtaatacta ttttttcgtc acacatatat
      241 agtgcgggtg ctagttcaga gcaatctgct ccaatgattt ttccttccat ttcattattg
      301 tttaatgctg ttttaaatgc attcactagt tcacaacgac gtccacaact taatattaaa
      361 atattcaatt tttaatctcc tatctattcg aagcatttgc aaaagtgaca atgtctttag
      421 ccaattgttc atcgtcttgc ggcaggctct tgacaaaatc catcactttt tgtattgagt
      481 aacctttgat gtttcctaca aagattttct cataaactgc ttcatcattt ctttccttat
      541 ccaacaatag ttcttcatat agtttttccc ctggacggat acctgtttca atgatttcga
      601 tttcgtcttc gctatacccg ctcaatcgga tcatgttttt cgctaggtct acaatcttca
      661 ctggttcact catatctaga ataaaaattt cgccaccttt tgctaatgcg ccagattgaa
      721 taactaaacg actagcttca ggaatcgtca taaagtatcg agtcatacga aagtctgtta
      781 cagtgattgg accaccttga gcaatttgtt ctctgaatac tggaatcaca ctaccgcgag
      841 aaccaaggac attcccaaat ctgacagctg agaatttcgt acagccttct tcattcaatc
      901 cagtcacaat catttcagcg attcgttttg ttgaacccat gacatttgga ggattgttag
      961 ctttatctgt cgataccatg acgaagtttt tcacttttgc tgctttagct gcttctgcta
     1021 cattttttgt accgaaaata ttgtttttga ctgcttcttt tggattatat tccatcagtg
     1081 gtacatgttt atgagcagct gcatggtaga cgatatctgg atgatattgt tccatgatct
     1141 cattgatttt ctcgcgatct tggatatctg cgatgatcgg tacgatttct gtaggacaat
     1201 tttgatgatg cgtgcgtaac tcacggtcaa tcaagtagat cgagttctcc ccatgtccta
     1261 aaagcaatag ctttgcagga ttgaattgaa tgatttgccg acagatttct gaaccgatcg
     1321 atcctcctgc gccggtgaca agaatgactt tgtctgtgat ctgatctttg atggattcaa
     1381 tatccagctt tacctcatct cttcccagta aatccactac gtcaattgtt tttaattttg
     1441 atacgctaat tttccctgaa gcaagttctt ctatagaagg catcgtgttg actttcacac
     1501 gagcggattc gactaactcg aagattcgtc gtaatttttt tcttgataag gaagggatag
     1561 cgatcgttac catttgaatg tcatattttt caatcaattc cggaatatct tttaatgcac
     1621 ctaatacttt ttttcctgaa agatacgtat ttcttttatt tggatcatca tctacaaacc
     1681 cgacaacgtg gatatcttga gccgttttgg atccaagaaa gctgttgtat aaaatacgcc
     1741 cgccttcgcc agcaccaaca atcaatgtat ttttagcaga atctgctgat acgtatctca
     1801 tattttttgt ttcgatgtag atacgccaga tcaatcggct accgatgatc aataagagcg
     1861 aaagcagata agcaaagata actaaccgta aactgtatcg ccgattaatg aacagcagta
     1921 tgaggatact tgaggcagca cttgcagata gtgaactaaa aattgcaatg atctctctta
     1981 aatttgtata gcgattgatc cgagtgaaaa ctttgaataa actaccataa aataaataaa
     2041 aaccaatcga caaaccgata gagattaaaa taagatccat tggtatagat acaaacggct
     2101 tcatgaattt agctgctgca atatttgcag caattaataa caagctgtcc acaaaaacca
     2161 atgtggcaat ttttcttctt cttgttaata taaacacttt ttaattcccc ctaaaataaa
     2221 ccaaacttct tcttttttac ctcttcatag tctggataac tgatttcatc cccgttgatc
     2281 agatcctttg caacttgctt catctgtact actttttcct taccaaagtc cttggcaatc
     2341 tgctcatagc actcttttaa gtaaaaggtg cgcttagaga ctccgtgtgc atcagaagca
     2401 gtcatctgca cgagattatg tttgaccatt gttttagctg ttttctgaat atctttgcca
     2461 aataccccaa cataacttgg cgcagtaagt tgggccaaac accccatatc taggaacgga
     2521 agcaaatgat tcgggtcttc gcgaaaatgc gcgttgcgtt ctggatggac gatcactggt
     2581 gtctttccta gttctaacaa ctcaaaaaaa agccgttctg catataacgg cacttccagt
     2641 gtcggaaatt cgatcagaag atatgtatca tctaaatctg taaataaaat ttcatctcgg
     2701 tggatgtctt cgatgagcgt tccggtaata cgtacttctt gtccttccaa taacgtcaaa
     2761 ggcaactgtc ttttctctaa ttcggcttgt aacgaagcga ctagagaaat gacttgtgat
     2821 ttttcattgc tgtattttcc attattgtgg tgtggtgtgc ataaaatatg cgtgatgcct
     2881 tgctgaatcg ctttttcagc cattgcaata cttgcttcta agttttctgc cccgtcatcg
     2941 attcctggta ggatatggca atgtagatcg atcatttctc ttgtctcctc tcttcttatt
     3001 ccttaatttc cgtagtaata accagcatct ttgctatgtt ctgctccgtt gtatacaaca
     3061 cctaaaactc gtgcttgtac catctctagc agttcttttg ctttattcaa tgattcttta
     3121 cgtgatgtat tttcacgtac gaccaataaa gtgccatccg tttttgaaga catgatctgt
     3181 gcatctgtta cggctactac tggtggcata tcgaatatca ccacgtcaaa taactgtctt
     3241 gcttcgtcta ggatctgatc cattcttggc gaacttaaca attctgatgg gttgggtggc
     3301 ttaggtccac taggcaaaat cgacaagttc tcgactggcg ttcgttggat tacatctgct
     3361 acacttcctg atgaactaag tgctgtactt aatcccctgg cattgttcag ctggaatgtc
     3421 ttatagacga cgggtttacg taaatctgca tcgactagta gaactcgttg accggattta
     3481 gcaaaaacga ctgcaatgtt tgctgcagtg gtggattttc cttctccagg acctgatgaa
     3541 gtcacgacaa tcgttttgat ttgctgacca gctgcggagg caaactggat attcgtccgg
     3601 atcgtacgat attgttcggc gattggtgaa gatgggtttg ttaatgtgat caaactgact
     3661 gcatgagttt gtgctgcttt ttgtttctgt gttcgtgcca tttttcttcc tcctagactc
     3721 ttgagcggct tctgcgtgat ggggctgttt tatcgtttgt agcttttggt cgtgcaggag
     3781 ctgttccttt tttacggata ccagcgttca attctttcgc tgacatttct ggaactgttc
     3841 ctaagattgg gaatcctaat gcatccgtca catatttttc atctttcact gtccgatcaa
     3901 gtaattcgaa taagaatgcc agacctacgc ctaccatcat tcctaatact aagccaatca
     3961 ctagattcaa tttattattt ggcgaaacag gtgtcgtatt ggcaactgca cctgaaataa
     4021 tcgagatttt atcgacattc atcacgtctt ttgcgttctc ttggaaaact tgtgaagttg
     4081 tgttagcgat ctgttgagca gtcactgcat tcgtgcttat tgcctggatc gagaacattt
     4141 gtgaattttg tgactgattg acggagatcg catctttgat ttgtccagca gtcattttca
     4201 cattgtcttc tgtttctaaa cgatctttga cttcatttag tactaaatca ctgacgatca
     4261 tatctttata cgtattgatc atttgcaggt tcgtattgac atcattgaca tttgctgtgt
     4321 ctgattgtgg cagtgtcacg atcaattgtg cttgtgaact gtattttggt gtcaagatga
     4381 aaaatgttac gattcctgag atggccaagc cagcaaacat tgagatgatg attgttacca
     4441 agtgtttgcg taatgtttca aaaatttctt tcaagctgat tgtctcttcc attttttctc
     4501 cactttccta tttattctct agattcattt gatcttttaa ttcttttttc acacgatcaa
     4561 gttcttgatc gctgactttt tgataggaga tattatcttg catgaagcct tctccttgca
     4621 gctgatcttg cttgatcgta ccaaatgcct cccgataatc taaagcgatt tttttcattt
     4681 catcaaagct catgtctgtt ttcatattcg actctagagc attcaaaacg gattgatagt
     4741 tgctgacacc gtttaaactc aatacttttt ttgctacacc ttctacgatc tttctttgac
     4801 gctcttgtct accatagtca ccatttggat cttcataacg catacgagaa taagataatg
     4861 cctgatcccc gttcaatgta attttaccga ttggaaagtc atagccatct tgtgagaaag
     4921 tgaggtcatt attgacttcg ataccaccaa ctgcatcaac gagttccttt agccctttca
     4981 tattgataga gacatagtga tcgattggga tgtctacata tttttgtagg gtatccatcg
     5041 ccatggcagc tccgccgaat gcgtaagcgt ggttgatctt gtcttttgtg tcacgaccta
     5101 cgatgtcgac atacgtatct cgaggaatgc tgacgatcgt tgtctgtttg tcttcaggac
     5161 tgactgtggc aaccatcatc gtatctgatc ttccttgatc gacccgacct aaatctccag
     5221 tatcaatgcc catcaataga acagagaaag attcttgttt gtccagatca actggtttcg
     5281 ttcgttctcc ttgggttcgt tccactgatt cgtaagtttt ctcaatagaa tgtgagagat
     5341 ccagatataa ttttgctcct actcctacaa ttgctaatac taatacgata agaactgcta
     5401 aaataatcag aaatattttt ttccctcttg attttcttct tcgtcttgcc atagtttcct
     5461 ccgtttgcta accttgcttg aatcaacgtt ttaactgtca ataacttata ttgctatagc
     5521 ccatttgctg agcaacagtt tgtgcttttg ttgcgtatgc tgcgcttatt ttttcattcc
     5581 ggatctgctc tatttgactg agcgccgtca aatattgatc gtaagtagcg gtggcagtca
     5641 cttgaccatc cttcaacatc gtatcgaata actgatctag ttgcgtgact tgcgcgatct
     5701 gagtatcagc gaatcctaga tattgcataa caaccgtttt ccaaggacta tctttaaaaa
     5761 agctcatatt ttcacgtaca cgagcgacat ctgcacttgt caccttttct ttgatgacga
     5821 catcgtctac agcttgctgc cagtttgata catttttagt aaataaatcg ttgacagctg
     5881 tctggatctt cagttttgat tctgcactat ctaactgtgt cacgattgct ttcttctcat
     5941 cttggattgc aacagcttct ttaggcaatt ctgattcttt gatgtcgtaa tcatctgctg
     6001 aaagtttgac agaggatagc ttatttgaca aacttgtgat tgtttcttct gttatttcag
     6061 ggtttagaaa atttttttct tttgtactat acagcttgtc tacttctttt gataaagaag
     6121 tcaaggtgtc tttttgattg gtgatggcag attctgcata attgatccgt tgctgatgtt
     6181 gccgctgatt attgatatgg taaccaaaca aacagatcgc aatagcacct gcacctaccg
     6241 ccacagcagt caatgacttg acgaatggct tttccataga ttcactccta agtattgatg
     6301 atagataaat taagatata
//
LOCUS       DADVXV010000117         6191 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.120, whole genome shotgun sequence.
ACCESSION   DADVXV010000117 DADVXV010000000
VERSION     DADVXV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.120"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..237)
                     /locus_tag="KB969_002614"
     CDS             complement(<1..237)
                     /locus_tag="KB969_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6870533.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEY"
     gene            complement(259..1116)
                     /locus_tag="KB969_002615"
     CDS             complement(259..1116)
                     /locus_tag="KB969_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6870534.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            complement(1134..1967)
                     /locus_tag="KB969_002616"
     CDS             complement(1134..1967)
                     /locus_tag="KB969_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6870535.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(1981..2778)
                     /locus_tag="KB969_002617"
     CDS             complement(1981..2778)
                     /locus_tag="KB969_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6870536.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(2811..3095)
                     /locus_tag="KB969_002618"
     CDS             complement(2811..3095)
                     /locus_tag="KB969_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBB6870537.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(3092..4093)
                     /locus_tag="KB969_002619"
     CDS             complement(3092..4093)
                     /locus_tag="KB969_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBB6870538.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(4095..5162)
                     /gene="gnd"
                     /locus_tag="KB969_002620"
     CDS             complement(4095..5162)
                     /gene="gnd"
                     /locus_tag="KB969_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBB6870539.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            5161..6009
                     /locus_tag="KB969_002621"
     CDS             5161..6009
                     /locus_tag="KB969_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6870540.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
BASE COUNT         1835 a         1364 c         1009 g         1983 t
ORIGIN      
        1 gtattcttta aattgatatt catcccaata gaatttagct ttctctggtg taatgacaat
       61 tgttttttgt cctgtacggc ttcctgcatt tttgtaaaga tctctcataa atttatcttt
      121 tgctacaact tcgtctacaa caaaaatgga attcactcca cttttttgag ataacgttac
      181 cattacttgc ccatggatca aacgctcatc cacacgcgct aaattgacta cacccatctt
      241 attcacgttc ccttcttttt ataaaatacc gattcctgct agcacaatta atattccagt
      301 cagccataat aatgcttgtg tgactttcaa tccttttttc gtatagaaca agtacacacc
      361 cattacgaca gctaaaggta atatccctgg cacgatttga tcaagaattt cctggataac
      421 aaactcacgt ccggatatcg caaatttcaa tgaagattct acttttacat agtttcccgc
      481 aagcaccccc atcataaaca accctaaaac tgatagcatt tcaatcgctg tctgaacacc
      541 agtgttttgc attaggcctg tagcattacg gcccatagtg aaagcttgtc ttgcgaaaaa
      601 tacccctagt aaaacctgat acaacccaaa gcagataaaa ggaaaaagtg cgcctaaagg
      661 acttccctgt tgtgcccaag gtaccgcgat tgcgataaaa atatattgga cggttcctga
      721 atcgattgca tctccgattc ctgctagtgc ccccatcaat cccgctttcg tgttatacat
      781 caagtcatcc tgcatcaaga tctctttttc ttcatactct tcttctgctc tttgctgttc
      841 catagaagac attaggccag taatcacacc gccaccccag cttaattgag tgttgaagaa
      901 cagtaactgc cgtttatatg ctgcttttaa agagtcttca tctttataaa gttttttcaa
      961 gattggcatc attccgtata gtagtgatgg cgccaagtaa cgttcaaaag agtgaggaat
     1021 ttcgtttgca aaatgccatc tcagataggc ttttgttaca tcttttttcg tgatttcttc
     1081 aggagcacct gtttgattat ccattatttc agccatttcc cattcctcct aaattaaaat
     1141 ccgtcatcat agtcatcttc gtcatcaaaa gatgctgaat tgttattgct tgtggcaggc
     1201 tgtacttgtt tccctttttg cgactggaca aagatcaaag cgataataat cccaaaaatg
     1261 gcataagtaa ccatcgtaat atctaaagat ttcaaaacaa cactcataaa ataagcaagg
     1321 aagaaaaaga ccagataatc ttttcgaccg ataacgtata cagttgtcgc gataccgatt
     1381 gccgctaacc ctccacctac tacttcaaga atgtggataa cgactgttcc ctctaaagct
     1441 ttgattacat cagcgatcaa tggcgcccct aaatataaag caatgaaaac aagcggaacg
     1501 aataataaaa atgaggcaac cgttggataa agaataattg atcgggccat agcttttgta
     1561 ttcaaatctt ctacagcttt gtctgtatat ttacctaaaa aagtattgat gaaaaaacga
     1621 aactgataca agtaacttcc gagcaatccg actggcaccg caacggcaat cgctgcttct
     1681 ggcgacagat cccctaataa tgcgactggt actgcgatag ctgctgcaat agatggttca
     1741 gctggcattg atcctcctgg agaaaaaacc cccatataaa tcatttgcaa agcggctgta
     1801 acaatcatcg cttgtgcaac ttcccccatg atcaacccga cgactaatcc agtcatcaaa
     1861 ggagaaaaac gtaaggtcaa cgtggctcct ccacctaacc agcgggacat aaccgcggct
     1921 acccataaag caatcaacaa actttgtact acacttaatg tttccatgtg tcctcctcct
     1981 tcagatcttt ctgatataac cttccagttc catcattgac tgtatcagtg atttctgtgt
     2041 tacctctata ggaatcaaat gcactttctc tttcgaatca ataaattcag ccattttatc
     2101 tattatctgt ttatctttcg gaaataatcc catttgttct agagaaaccg gcagttctaa
     2161 ttcccgatac aaaggatata actcgtctat tttttcccag cgaccttcta gtgccagttg
     2221 atagaaaatc ccatacgcta ctttttctcc atgtagaaaa cgatggcttt ccggaatata
     2281 tttactgata gcgtcatgca tagcatgtgc tgccgcattt cttgcgtatt tatctcctaa
     2341 tcctccaact aaaccagcaa cagcaaagat aatctctgaa agctgtttga actccgatgt
     2401 cagttttctt tgtgccatat cttggattgc tttagcagaa tgattcaaaa tctcttcttt
     2461 gcagatcttc gcagtatctt gtgctagctt caaaaatgat tcatcttgca aaaaatcttg
     2521 ttctaagatg agctcagatt cataccattt tgctagtgta tctgctaacc cggcaatgaa
     2581 atatggaaca ggggaatcaa tcactaattg gggatctgtt ataaaaaaag cagcttgtct
     2641 gtaaaagtgt tctgttttcc cttctgcttg tccattctcc ttatacatga cagcaagagg
     2701 tgtccatgga gcacaattac tagctaaagt agggatgact ccgaaatcga ttcttgcaag
     2761 attggcacta taacccacta gatcggtcag ttttcctccg ccaacgccaa ctacgaaatc
     2821 gatttcattt ttttgatgat tgtagctatt cgtctggctt cagcataact acattctcca
     2881 gaataacgat gataaaaaaa ttgaatcgtt tcgtcattca aaaatactaa tttaggtagc
     2941 gccttttccc atgataccgt tccgtgggtg accagtactc ttttcgcgcc gtatgatttc
     3001 aagagatcag aaacttttga aataccacct tcttcatata aataaaattg agggcctgtt
     3061 ttcactttta aaccgttcac cattttcttc atcatccttt tatatagttg ctctttgtct
     3121 ggacagaacg ttcaggaaga aggtgctgac tgatctgttc gacatctctg acacattttt
     3181 cacccattgc ttctaaacat tcccttgtgt aggccgatat atgtggcgta atcactactt
     3241 gttcaaacgc taaatacgga tgatcttgac gtcccggttc ttcttctaaa acatctgtgg
     3301 catatcctgc gatctttccg cttttcagac cattaatcat cgcttcttca tcaactagag
     3361 cgcctcttgc actattagat agataaacat tttctttcat ctgatcgact tctttatcag
     3421 aaatcatgtg atagttctct tctgtcaaat tcgcacataa acaaatgata tctgattgtt
     3481 ccagtaattc ttgaagttct actttttttg caccaaagct ttcgatgtat aaatctgatt
     3541 tgtaaggatc ataagctaga acatcacagc gaaaaccgtt acgcaaaatt tcgattactc
     3601 cgcttccggt atttcctgca ccaatcacac caactgtttt gttaaacagc gtcctaccga
     3661 cgaactccgc ccgatcttcc catcgatcgt ccttgactct tgcttgtgct tgtgtcgtgc
     3721 gtcgaagcat ggacaacaaa ttagttatat tattttctgc tacagcattt cgttcaatta
     3781 aagcaggtat gatagatacg attgtctggt gttcttttgc tgcttttaaa tcaatattgt
     3841 tgtaaccaat accatgtcgg gaaatcaata gcagttcatc tttgttttca aaaaaatctc
     3901 gtcgaaaaaa tggcgtaaca cttgcaataa tgatattgaa tcctttaagt aactccgcta
     3961 gttcttttcc tggaatctct tgatcaacag taaagaaatg aacgtctcca actgacttta
     4021 atctttccaa gtggtgtgga aagactcttc cgaaactgct ggaattaacg attgctatat
     4081 gataatctgg cattttactc acccttttca actatttcat gtccgccaaa cccatttctt
     4141 agtgctgaaa ctacttttgc tgaaaaacta tcttcttcct gtgaaagatt cctcatgaac
     4201 aaactagttg caattactgg aactggaaca gccatttcta gcgctgtttc aaccgtccat
     4261 tttgcttcac ctgatgcaga aacgattccc cgataattac ttaaattggg atgttcgttt
     4321 aactgatctt ccatgatttc catcagccag ccgcgaatca ccgaaccatg attccaaaca
     4381 cgtgcgactt gttccaagtc aaaagcatac tcactttttt gtacaagttg gaatccttca
     4441 ccgattgctt gcatcattcc atattcgatt ccattatgga tcattttcaa gaagtgtccg
     4501 cttccggatg caccagcata cagatatcct ctttcaattg ctacatcttt gaataattgt
     4561 tccacggata gaaaagtttc tttatctcct ccaatcatta agcaggcttg atgtcgtgct
     4621 ccttcgattc ctccagaagt cccacaatcc aagtaaccga tttcattttt ctgaaactct
     4681 tctgctcgac ggattgaatc tttataataa gagtttccgc cttcaataat aatgtctcct
     4741 ggtccgagtt ttggaaaaag ttttcttaac atgttttcgg ttatctctcc agcaggaagc
     4801 attaaccaga tgattttttt ctgctcaaaa gtagctagaa attcagagat ctcttgataa
     4861 gcaggaatgt cattttctct tgcctgacta acagctgtac ttgaaatgtc gagtccttgt
     4921 actttgtgat ggtgctcttt taagtttaaa gctaaattca atcccatttt tcccaaacca
     4981 attacaccaa tttccatgat agcgcctcca tttcttatac cctcattata caaaaaaatt
     5041 tttttgtaaa tagattttac aaaaatattt tttgtttgat tttttcctac tctccttgta
     5101 tctttaacat taatgagaac ggaaaaaatg ataatcttat tatgaaaatg aggaattctc
     5161 atgagcgtct ccataagact acaaatcaaa acaatgtaca acgacttcag cccaaaagaa
     5221 caggctatcg ccgattatat tttagaaaat ccaagcaaag taagtcatag tcctattagc
     5281 aatttagcaa gtgaactggg cattgctgac tctacttttt ttcaatttac aaaaaaactt
     5341 ggttataatg gatttaaaga ttttaaaatg gccatgttga tccaagaaaa tgatctatct
     5401 gctatttcta tccacgaaaa tattcagaaa acagatactg agctcactat ggcgcaaaag
     5461 gtgttcgagt ctagtatttc aactttaaat gacacaaaaa agttgttaca acaaaaggat
     5521 ctaaaaaaag cggctactat tatcaatgaa tctaaacgtg tctatttttt cggtgttggc
     5581 ggttcagaga ttgtagcaac tgacgcttat cataaatttt tgcgttcccc tatcgcaact
     5641 tctcacagca cggattacca tattcaattg atggaagctt ctttattgac ggaaaaagac
     5701 tgtgctgttt tgatttctca cacagggcaa tcaaaagaaa caatccatat tgctgaaacc
     5761 gtaagaaaaa ctggagcaaa aacaatcgtt attactagcc aagctaattc ttcccttgct
     5821 aaacttggcg atgtcgtttt tatttctatt tctgaagaaa cagaattccg atctgaagct
     5881 ttagcttccc gtatttctca actaagcatt ttggactctc tatatgtgat tttgatgttt
     5941 tacaacgaaa aagaatcacg tcgttctatc gctaaagttc gacatactat ttctgaaatc
     6001 aaagaatagc accataacag aaaaagcgaa aaatccataa aacaaaaaaa gccactacca
     6061 aatatttggt agtggctttt ttggttctgc aagggtggta cagaacatca atagtcggtg
     6121 ggttagaacg tatgtcatcg catctttgga gaaggttgta ttggtattat tcgagttact
     6181 tgttagatgc g
//
LOCUS       DADVXV010000118         6173 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.121, whole genome shotgun sequence.
ACCESSION   DADVXV010000118 DADVXV010000000
VERSION     DADVXV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.121"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            725..811
                     /locus_tag="KB969_002622"
     CDS             725..811
                     /locus_tag="KB969_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBB6870541.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="KB969_002623"
     CDS             complement(932..1621)
                     /locus_tag="KB969_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870542.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="KB969_002624"
     CDS             complement(1866..2780)
                     /locus_tag="KB969_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6870543.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="KB969_002625"
     CDS             complement(2762..3142)
                     /locus_tag="KB969_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBB6870544.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="KB969_002626"
     CDS             complement(3592..3879)
                     /locus_tag="KB969_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6870545.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="KB969_002627"
     CDS             complement(3899..4123)
                     /locus_tag="KB969_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBB6870546.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="KB969_002628"
     CDS             complement(4578..4748)
                     /locus_tag="KB969_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870547.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="KB969_002629"
     CDS             complement(4763..5296)
                     /locus_tag="KB969_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6870548.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="KB969_002630"
     CDS             complement(5317..6159)
                     /locus_tag="KB969_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6870549.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DADVXV010000119         6124 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.123, whole genome shotgun sequence.
ACCESSION   DADVXV010000119 DADVXV010000000
VERSION     DADVXV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.123"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..243)
                     /locus_tag="KB969_002631"
     CDS             complement(<1..243)
                     /locus_tag="KB969_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870550.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLI"
     gene            445..744
                     /locus_tag="KB969_002632"
     CDS             445..744
                     /locus_tag="KB969_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870551.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            1009..1884
                     /locus_tag="KB969_002633"
     CDS             1009..1884
                     /locus_tag="KB969_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870552.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            1881..2099
                     /locus_tag="KB969_002634"
     CDS             1881..2099
                     /locus_tag="KB969_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870553.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            2086..4713
                     /locus_tag="KB969_002635"
     CDS             2086..4713
                     /locus_tag="KB969_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870554.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            4728..4946
                     /locus_tag="KB969_002636"
     CDS             4728..4946
                     /locus_tag="KB969_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870555.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
BASE COUNT         2385 a          764 c         1174 g         1801 t
ORIGIN      
        1 gataaggtat gaagttatat attcttctaa agttccccat ttaatccagt caattgttga
       61 attagtgata gttgataata atttcagctt ttgtggattt ggtaaattgg tcccacgttc
      121 ccagttggat atggtcgcac gtggtgaatt atctattttc cttccaagtt cttccatagt
      181 aaaaccacat gaaaggcgta attgtttgat tcgttttcct gcttctgaag gatttggctt
      241 catctttttt ctccttttta tttttaaaga tagtatatca tatttataaa ataaaagtat
      301 ttaaaagtat ttacttttta tctggagtat gatactttat tcttataaat acaaataaat
      361 acattttttt acgcaatttg tatttatttg tacttataaa ggtagaggag ttatagaata
      421 attaattaaa aaggagaggt ttttgtggaa gcaataaaat taatgatttc agaagaacag
      481 gaggaaatgt ttctaaagca gttttatcaa attgctacaa aagctattga aaaggctcaa
      541 gaaaatgcgg ggatgacaag ggaatatctc aatcaaaaag aaatggcgga atacttaaat
      601 gtgagtgaaa actttttaaa aaatgctgtg agaaatgagg gattgcccgt agttgaatta
      661 ggggcaagaa aattttattc gaaaaaggca gttaatgagt ttatgtttgc tcgaatgaaa
      721 agaggggaaa atattggaag atgatgaagt agaaattata aaaaaatgct ttaaaaaaag
      781 aaaaaaagtg ttcccaaaag tttgcagact gggggaacac tcaataataa agtgctgaga
      841 aaactttatt tatagctatt atatcaaaaa agaaggtgaa aaggtgtttt cttctggaaa
      901 tgttgtagtt gacaaactta gagaaataaa ttttgacgga aatgtaatcc acacacatgg
      961 tacgatcaat taagaaaaaa aacgaaaaaa ggtgttgaga agccctattt gaatgcaata
     1021 gttatcttag cagaaattac ctattggtat agacctaaaa aaatttttaa cgatgatggt
     1081 cagctacttg gttatcaaaa aaagtttctt gaagatattt tgcaaaaatc atataagcaa
     1141 ttaagcaaaa aaacaggatt atcagaacga gctataaaag atgcaattgt gtacttagag
     1201 aaaaagggga ttatcaaaag ggtttttaga aatatttatt atgagaaaag agcagttaca
     1261 ttatcaaatg ttatgtacat tgttttaaat gtacataaat tgatagaaat tacttttcct
     1321 actttggatt gcgaaaaaaa ggagtatatg ccgaaaattc gtcagagggg tatcgaaaaa
     1381 aagagatatg tctctttaaa aaaaggtaga ggtatgtaca aatttgtata tacgtataca
     1441 aagactactt cacagaacat atcaaagact actctcgtta tggaagaaga ggatattaat
     1501 ataaagagga tttacagtaa gattagtgtt ctttatgacg caaataacga agatggtcga
     1561 aaattatttc aagtgtatca ctatttgaga aacgctaatg tagatacaga agatatcaga
     1621 aaaatcattg aatatttatc tgaaaatact cagtatctta ttgctgagtg tattataaaa
     1681 caacatgaag catgcttttt tcaaagaaaa actgaagaag ggttatacga ttatgtaaca
     1741 tattttttga atggacttca gaaaagatat aaaagtcaat ttttagaaaa tgtagagcct
     1801 atagatcagt tcaaaaaagc tttcgaaatc aaagagttac ctgaaattac tatgcataat
     1861 tggttgaaag gagaagaatc atgattaaaa atcgcttaat agatcaaatg tggtgtcttg
     1921 atcaaaatac agatactctc gaattaatcg agagtatctg cttcaacaca gtagttctcg
     1981 atttaagagc tgaaaatgac aattgtgtaa ctcatatcat aattaatcaa aaaatggctc
     2041 agcagctctc tgagagccta agaaaatggg ctgaaggaga aaactatgaa agcaattaaa
     2101 gaaaaaatcg ttagtagaaa aataaactgg ttagcactca gtgtacttgt tttaatgatt
     2161 agcgttgttt ttacaagtaa tattgttgaa gctagcattt tcaattggtt tgatgacaca
     2221 aaaagtcaaa cagagttttt gaataattct ctttatagac cttacctaaa aaaatacaat
     2281 ggagatttcc ttagtcagtt cgggatttgg cttggatggg ctgtggtaaa aggcatgttt
     2341 actgtgactg attcgattca aaatatgatt ccagatgtgt tggatttgtt caatttcatt
     2401 gaaagtacag ggctaaataa tgtttatcaa tcagtcataa atacaattgt cgttggatta
     2461 atgatccttt cattgatgtt tgttggctac aagatgatta ctggaaaagg aacaatagat
     2521 ttaagatctg ttggaatgaa tatagtgatg tctgtagcgt taattctttt aatgccaaca
     2581 atgatttcta gcggtattca atttgccaaa atattttaca atgatgctac tacgattaca
     2641 aattcagatg acggagtcgc ttggtcattg ataaaacaag gagtaacaga tctggcatat
     2701 attaataaaa cagatcaata ctcaagcatt gataaaacgg aggatcgaaa taagttaaca
     2761 cgaaaaaatt ttcaacagac agatttaaca caagtgttga cggataaagt gattgataaa
     2821 ttggaaaaag aaaatccagc tgcggataat cttcgctatg aattagttga aaattctaat
     2881 aatgaatttg ttgccacaaa gttttctgat aacttcttat caacattttc tgatagcttg
     2941 aaatcaggtt attatcgata tcaagcaaat ctttggggga tttcgattgg gttgacagcg
     3001 ttggcaatcg cctatgtgtt cagcgcgttt gtgatcatta cagcaatatt agaacttgca
     3061 tttaaacgtg tgttaggtgt tcttgttttt gcgacagata ttgaaacagg acaacgttca
     3121 aaagttgttt tatccgatat tttacaatgt tacttaacag ttggatttca agggtttgga
     3181 ctatctatgt ttgctatgtt tatcaatttt ttaaatgctg gacaaggtat ctccacaaat
     3241 atttttataa aaacaattgc ttatatctgt gctgtgtttg tgctgataaa aggcagtgga
     3301 acagtcatga gatactttgg tgttgatatt ggactcaaag aaggctatgg gcaacttgct
     3361 tctgcttttg gtatgggcgc aatgctgttt agaaaaggat caactggatt taatcgtgct
     3421 aaaggaagcg gaaatggaaa tggatcagac agtggagaag gagaagatcg aaaaccagaa
     3481 aagaatttcg gcgaaactct atcaaaaaaa gctggcaaaa ctggaagagc tttgggatat
     3541 gcccatgaac gtggattatc aggtttagct tcagatggag ctacaatggc tagtgaaaga
     3601 gcaataaaac catttaagag tatgcgtgat atggctaatg ataccaagaa taagttcaaa
     3661 gaaggtttag atgatggtac agtgtccgct attaataaaa atagcaaacc tatgttagct
     3721 aaaaataaag aagatgaaac tggaaaatat gctgattcca tgccaacacg tctttcggat
     3781 agaaaagatg gtgctaaggt tgaaaatgcc gatagaatta tgtctagttc tgaacgtatg
     3841 cgtgaagcaa tgaaaaataa tgctgaatcg aataataatc ctgtaagtgc aattcagcaa
     3901 aaagttcaac aagatattga agaacgtaaa aatgctatgc acggtcaagc taagtctgct
     3961 gaagaattaa ttaatcagaa gcgacaagaa gctaaataca cgcctgaagc aatgaatcgt
     4021 gaggaaatgt taaggaaacg tgtagaaggg cgtacaggag ctaatacgga cgaaaaagaa
     4081 gcgttgacca aagaaagaat ccaagaagct aaaaactcaa ataccggatt agaaaaattg
     4141 gtcaaagaaa atctacaaaa ttctacaagt agtcaaggtg gccgatcagt agatgtccga
     4201 gaaaatattc aaggttcatt gaatggtcat gtcggacgga atgttgatgt aagagagaat
     4261 ttacaaagct cttcaaatgg tcaaggtact aagacaattg atgttcgaga aaatgtacaa
     4321 aattctacaa gtagtcaagg gtttaaatca atggatgtaa gagagaatgt acaaaattct
     4381 acaagtagtc aagggtttaa atcaatggat gtaagagaga atgtacaaag ttctacaagt
     4441 agtcaaggat tcaaaacagt agatgttcgg gagaacgttc aaaaagatag tggagaaatg
     4501 aaagaaaaaa cacaaaaaat caatatcgtt gaagacagaa agtcagcgaa aaaatttgat
     4561 tcaaatcatg aaacagtgat tattgatagt gaaatccgtg aaaatgataa gggatcaaaa
     4621 ccaagacgaa gatttaccta tgaagacaac gagttattca gagatacact taatgatcct
     4681 aatccgcttt tcgataatct attaaaaaaa taaaaggggg aattgtcatg aaattaattc
     4741 taaagattag tacgcatgat ttcttagaac ttgacgaatt atgtgaatca gtaaagaacg
     4801 caacaaatga aaaaatcacg gtcactaatt atattgaact gatgattcaa gaagaattaa
     4861 agatgaaaca tgagataaaa aacaacttga aatattgtta tctagaaaaa agtgaagaga
     4921 taatccatga attaaatggc ttttaaaaat tgtatttgac atgaatttac gacaaggaat
     4981 tagtggggat taagcgatta ttctcttcca ctttagagaa ataatgggtt aaaaagccag
     5041 aatacgtaga gcaatattga caacctataa aggagctatt gttgaaaatt gaagtaacaa
     5101 aaagataaag ggaggtttac atctatcaga ttaaaagtga tagtacaccc atgaaacctg
     5161 caaaagagtt gaacctaatg tatatcggtt taactctttt tatttgcaaa ttaaaaaaat
     5221 atcaccgaag tgacgaatga aactatgacc aaattaagca agaaaatata tcttgcaaat
     5281 aaagtagtat aaaaagatat tgataaagcc aatcaaaact ttgaatttca aacgttagat
     5341 aatcaaacag atacaaaaaa tgaaatcagt tctacgcgta cgattattaa aaataataaa
     5401 ttttcactag aagaaaatgg aaataaaatc aaataattag gaagaaaaaa caaagcaatt
     5461 agaaaagcct gcaagcaaat ttgagtaatc gagatccaat ttttttaagg aagtttaaca
     5521 aaaatatgta attctattat cactattaaa gagaaagttg gagcggaata taaagaaaag
     5581 agaaaagtaa ttaaacgcaa aaaaatgtag aacttaaaaa atataaagag gaacaaccgt
     5641 taaaattagg aatgatgttg tgtaaacatt ataattgcta tgatataaat gaagtgttaa
     5701 agaaagcaaa tttaaaccaa ttttgtgaac agaaaagcct tagtcactat gaccaaaact
     5761 acggacgaaa ctatgaccaa aagtaggtac taaattatga ccgaaaatag gtccaaaatg
     5821 gattttttta tgatatcaaa aattatgaaa tgattttgaa agaaaaccag ttggcacagc
     5881 caacttagcc accttcctgt aggaaggtgc tatcagtttt cccttatgct cttttctttc
     5941 ttttttgttt catatgtcaa atgccatttt gaaatgtacc atcttaagaa atttatcctt
     6001 aaaaacaatt gcgttattgg ataaaaagat gctacattat cttaaaaaag gaatcaaata
     6061 tgatgaattt agtggctagc atatcgtgtg attaagatac tttatagtgt aagttgaagg
     6121 agaa
//
LOCUS       DADVXV010000120         5888 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.124, whole genome shotgun sequence.
ACCESSION   DADVXV010000120 DADVXV010000000
VERSION     DADVXV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.124"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(173..1177)
                     /locus_tag="KB969_002637"
     CDS             complement(173..1177)
                     /locus_tag="KB969_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBB6870556.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKETVETDTTIEAKKSKTQS
                     TEQTTTEMKQSVEASTSESSIIESSSEEVKNTLWDSEKSTQLAIFVPQWGKTLGQEYK
                     SYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVET
                     GEYLGQHVYFFGFQNGQPKVYLTQQNQGNDKNYMYFNETQNQQLKQGFIDIVNGQTPQ
                     TPVVEESTQQATTTTTQSTSSSAISSWEAAKETVLNNKALWLYDSPDKNASNTNLIST
                     NEYMKDLMQDENGSYYSINIVTDDNGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK
                     "
     gene            complement(1248..1544)
                     /locus_tag="KB969_002638"
     CDS             complement(1248..1544)
                     /locus_tag="KB969_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870557.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHAGYRHSWERIN"
     gene            complement(1537..1830)
                     /locus_tag="KB969_002639"
     CDS             complement(1537..1830)
                     /locus_tag="KB969_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870558.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1976..2527)
                     /locus_tag="KB969_002640"
     CDS             complement(1976..2527)
                     /locus_tag="KB969_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBB6870559.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFPRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2701..3000)
                     /locus_tag="KB969_002641"
     CDS             complement(2701..3000)
                     /locus_tag="KB969_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBB6870560.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGMLPEDVT
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTNE"
     gene            complement(3027..3335)
                     /locus_tag="KB969_002642"
     CDS             complement(3027..3335)
                     /locus_tag="KB969_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBB6870561.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQFHLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEARKEYLISPKLRLKSVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            complement(3452..4411)
                     /locus_tag="KB969_002643"
     CDS             complement(3452..4411)
                     /locus_tag="KB969_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6870562.1"
                     /translation="MTYTHLTTDELVIIESYFNIEKPVALVAQSLNRSRQTIYNVYSF
                     LKQGKKVLDYYRQYKQNKSRCGRRSTVLSDEQSTYVQEKVAQGWSPDVIIGRGEFPID
                     CSVRTLYRMFKKGLFDTQSLPMKGKRKPNNHQEKRGKQAFRRTIHERNSLYPHLTKEF
                     GHLEVDTIVGVKHKSAVITLVECLSKVIITLKPTGRRAEDIENRLNDWFKSMPKHLFK
                     SMTFDCGKEFSNWRSISNSNDIAIFFADPGTPSQRGLNEHSNGLLRRDGLPKTMDFRD
                     TDETFIQSVASKRNHIPRKSLNYRTPLEVFLSCIDKDILSSLI"
     gene            4555..5331
                     /locus_tag="KB969_002644"
     CDS             4555..5331
                     /locus_tag="KB969_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6870563.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLAESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            complement(5429..>5888)
                     /locus_tag="KB969_002645"
     CDS             complement(5429..>5888)
                     /locus_tag="KB969_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6870564.1"
                     /translation="LELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIKMAIAS
                     SSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEECLVIED
                     SYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
BASE COUNT         1782 a         1075 c          881 g         2150 t
ORIGIN      
        1 attgtttaca aactagatag cttatgtatt cttattaaaa ataatagata tttcgaacat
       61 catcactctc atctacttaa tttcgcattt ttactttata aaaaaactga ttctaagaaa
      121 attaaataat ttttctcaaa atcagttttt ctttgataaa taatattttc aattatttaa
      181 tcatttgaaa attgttagtc attccaatac gttgagaaat tcttccatct gtataaacac
      241 ggaattgttt tccaccagcc attgttgtat ttccattatc atccgttaca atattaattg
      301 aatagtagct tccattttca tcttgcatta gatctttcat atattcattt gtgctaatta
      361 aattagtatt tgatgcattt ttatcaggag aatcatacaa ccataaagct ttattattta
      421 gtacagtttc tttagcagct tcccaacttg aaattgctga gctacttgta gattgtgtcg
      481 ttgtagttgt tgcttgttga gtagattctt ctactactgg agtttgagga gtttgtccat
      541 tcacaatatc aatgaaacct tgttttaact gttggttctg agtttcattg aagtacatgt
      601 agtttttatc attgccttga ttttgttgcg ttaaataaac tttaggttgt ccattttgaa
      661 agccaaagaa atatacatgc tgccctaaat attctccagt ttctacatca gaataaactg
      721 ctactaaatt gaaatctgca tgaccagttc catcttctga ccattgtacg gtaactggtg
      781 cttcattgat tgccattttc caatttccat caataactgc acttggtaaa ggcgtaccat
      841 acagacttac attgttctga ggattgtagc ttttatattc ttgacctaat gtctttcccc
      901 attgtgggac aaaaattgct agttgagtag atttctcact atcccacaaa gtatttttaa
      961 cctcttcaga agaagattca atgattgaac tttcacttgt acttgcttcc acagattgtt
     1021 tcatttctgt tgtagtttgt tcagttgatt gcgttttact ttttttagcc tcaattgttg
     1081 tatcagtttc tacagtctct ttagtcctcg tattctcaga tgtacaacca gtgaataaaa
     1141 tccccattcc aattagtaat aacaaccatt ttttcatttt atttccccct ttcaatttct
     1201 ccctcgcgta cttattttat cagtcaatta atctcaatgg tgttcattta gttaatcctt
     1261 tcccaagaat gtcgatagcc agcatgacaa cgatctcttc cttgagggct ttcagatgga
     1321 ttaaaactag tagaaatttc ccttccacat cctctacagc gataagttct cattattttt
     1381 gggctattag tattattttt cttagttaga gctatgagtc caactatgat taccccaact
     1441 gtcttaatta cttttccttt atctatattc ggatgcgcaa gcatatattt atataaccaa
     1501 tatccaccgt aaattaaacc acctaataca atcagcttag ccatgtactc gtctcctttc
     1561 tttttgttta attacttttt gaatccatct tgcagagaaa ccataaactt ctgtcaattg
     1621 acggatatct acagtttttt cctgttctat catgttttcg attctttttc taactaactc
     1681 acgatcgtac attttcattg gaaaagaaat ctgttgccct cgaaaagcaa gataaaattg
     1741 atagagcaat tctgaatcca gttccatttc ctcaaaaaag tcattcatac ttttataaga
     1801 gttactcaaa caagtttcat caatctccat ctacacaccc cctgttattt tttacataat
     1861 gaaaatagca tattactggg tacattgata attcatataa catgtatcat cacatgtatt
     1921 tttaaagtca aaaagcatgt aaaactactt ataagtaaca taagaaaata aaatgttatt
     1981 tttcttgaaa taataattga ctatctgcca attgccattc attacgaaca tgaatactta
     2041 gtgggtggga taacttacct tctgcattta tcaatacttt ggtcatcttt ttttgtttcg
     2101 cactcaattg atcgtaaatg gtcttcgctt gttcataagc cacttgactc gtcgctgtaa
     2161 tcgaaccaca agcaaaaata atggtgttga ttttcttttc tgtgaaaaca gttgttaata
     2221 tttccaaaga ttgttcatca tttccacgag gaaatacccg aggacttttc gcttttgtat
     2281 acgaaaaaag attcacagca ataaaaccag taaatcctaa ttgtcggata ttcttttcga
     2341 ttaataacat actcaaatca ttcgtaaatg gttctgtatc tgttggacga atagtaatga
     2401 ctaccgctaa tttatcttcc gcttcttttc ctttgatcgc ccattgtcgt ttgaaaacat
     2461 agcgatgggt atgatgagga tctcgccaaa cttctgtttg tgtggtcact aattcttttt
     2521 caatcatctc tttttctcct atgctaattt ttgttcaagc aattcaatca ccattgccgt
     2581 tataagtgtc aatactagtt gaaaatattt catattcttt ctcctttttt cttcagaatt
     2641 tgatgaatcg ctgtaaggat atcttctaaa catttcgcaa tcattctcaa ataatcgatc
     2701 ttattcattc gttcctccaa tctgactcca aaccaatcgt ccttctacca gtaacccacg
     2761 aacaaattct cgctggctgg taatatctgt aatgaaataa actacatagt cttttccatc
     2821 ttctggtgcg caataaatat aaagatgtgt catcactaaa cgtggtagag taacatcttc
     2881 aggaagcata cccatttcaa tttcctcttt ttccatcgta acggattcat agccccactc
     2941 ttcaggagta gtgactagct gtgcacactt ttccagtact tcgatagccg tttctaacaa
     3001 gtcctttcgt tcctttcttt tagatatcag tattcttctg gtaataacat cgtttgatac
     3061 tcacccgaat caatgaccca tattttttga gacactgatt tcaaacgaag cttaggtgaa
     3121 atcagatact cttttcttgc ttctggttct tcttgacgat gaaccaactt ttgatttcct
     3181 ttttccgtag aaaattcaaa gatttgaaga tagtctaaat gaaattgctt ttgaacgttt
     3241 tgatcgatta gattccaaca taaagcttgt aattccaccg gcaaactgtc cattactccc
     3301 tttgtgacat aacgttgtcc tttattttga aacatttctt ttccctcctt tgccataaaa
     3361 atagcccaat cttctattaa agaagattgg gcttcatgga tataatatat atttgatatt
     3421 caatttgatt cattttatac tatctgattt gtcaaattaa gctagacaat atgtctttat
     3481 ctatgcagct caaaaatact tccaatggtg ttcgataatt taatgatttt cttggaatat
     3541 ggtttctttt cgaggcaacg gattgaataa aggtttcatc cgtgtcccta aagtccattg
     3601 ttttaggtaa gccatctcgt ctaagcaagc cgtttgagtg ctcatttagc cctctttgcg
     3661 aaggtgttcc tggatctgcg aaaaagatgg caatatcgtt cgagttactt atagatcgcc
     3721 agttggaaaa ttcttttcca caatcaaatg tcatggattt aaacaagtgt ttaggcatgg
     3781 atttgaacca atcatttaac ctgttttcga tatcttcggc tcgtctgcct gtcggtttca
     3841 aagtaataat aaccttggat aaacactcaa ccaatgtaat aacagcgctc ttgtgtttaa
     3901 ctcccacaat ggtgtcgact tcgagatgac caaattcttt agtcaggtgt ggatagagac
     3961 tgttccgttc atgaatcgtt ctgcgaaagg cctgttttcc acgcttttct tgatgattat
     4021 tcggtttacg tttccccttc ataggtaacg actgtgtgtc aaaaaggcct tttttaaaca
     4081 tccgatagag tgtacgaaca gaacaatcaa ttggaaactc gccacggccg ataatcacat
     4141 cgggtgacca tccttgagct accttttctt gaacatatgt tgattgttca tcagataaaa
     4201 cggttgaacg tcgtccacaa cgagatttat tttgtttgta ttgacggtaa taatctagca
     4261 ctttttttcc ttgtttgaga aacgaataaa cattataaat ggtttgtcta gagcgattta
     4321 aactttgtgc gacaagagcg acaggtttct cgatattgaa ataagactct atgattacta
     4381 gttcgtctgt tgtaagatgg gtgtaagtca tttgtactca ctccttatta attctttggt
     4441 cggaactatt ttgagtgtag cacaaatgat ctttttagtt gtctagctta attttacaat
     4501 cgacgtttta ataaattgtg atataatgaa gtataacttt ttagggagtg tactatgaat
     4561 tttcaagata atagaccatt atatttacaa gtagaagctt ctatacgtaa cgatattcgt
     4621 gaaaaaaaat atcttccagg agagcaatta cctacagaag aagaattatg taaaatttat
     4681 ggagtaagta agattaccat tcgaaaagct tttaaacttt tagcagaaag tggaacagtt
     4741 gaacgattaa gggggaaagg gacctttgta actcaaaaaa aagaaagttt aaaattagct
     4801 ggagttcatg gatttagcga ttctctttct acccgaggac ataaaattag atatactgtt
     4861 ttacattcta aaattataaa ggctgatgag tttttagcta ataaattaca aatcaatgta
     4921 actgatagag tttacaatat taaacgttta atgtgggaag acggtgcccc gatgggaatt
     4981 gataattttt tcgcatcaga agaaaaattt ccaactttat ttgaaaaagg tagccaatat
     5041 acttcattat ataaacttct agaagatgac tatgatgtca aagctacgag ctctattatg
     5101 gaaataaacg gtttatctgc aacacctgag ctttccgact tattgcaatg tatagtagga
     5161 gatccgctat ttattttaga aaaggttggc aaagataaaa ataatcaacc atttcattat
     5221 tctcaatcca cagttcgttg tgatagaatt agttatgtta ttgaagtcac agaaaatatc
     5281 actttagata cggtgcataa aaatgattca gatcctaaag taatagattg atattaaaag
     5341 aaatcatacc caaagcaatc aattttgatt agatttgggc atgattttta tttttactaa
     5401 tattctctaa atacatcaaa aaacttattt atattccaaa tttcacctgt acttcttgtc
     5461 gcagatattt aatatcgtaa ataacatcat ctgctagact tacatcttga gaaaaacgtt
     5521 tatctttaat tgcaagaacc ttcatatttg ctcttttacc agcttttata ccattataag
     5581 aatcttctat caccagacat tcttcaactg gaattctgag ctgttctgaa gctttaagga
     5641 atatagtagg attaggttta ctttctggca aatctcttcc gctaattaaa caatcaaaat
     5701 atgactctat tttacaagtg gtaacaactt catttatagt atccattgga ctggaagaag
     5761 caattgccat ttttattttt ttctttttta accattcaag ctgttcaatt agtatattag
     5821 gaaaaatatc caagtaatca atcttttgcg atttccaata tttagtaaat tttcccttca
     5881 attctaaa
//
LOCUS       DADVXV010000121         5779 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.125, whole genome shotgun sequence.
ACCESSION   DADVXV010000121 DADVXV010000000
VERSION     DADVXV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.125"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..813
                     /locus_tag="KB969_002646"
     CDS             <1..813
                     /locus_tag="KB969_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBB6870565.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSLTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKIARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="KB969_002647"
     CDS             807..1229
                     /locus_tag="KB969_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870566.1"
                     /translation="MVNKLIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2363..3331
                     /locus_tag="KB969_002648"
     CDS             2363..3331
                     /locus_tag="KB969_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBB6870567.1"
                     /translation="MANEIVKYHHELNTIPLRKFTSVEMNLFFSIISRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGIA
                     NFSKEDFHELLDIPKSYRESDINKKIIKPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKEPTSLQEKIKEQKRKLELL
                     QQLAELERKQNTPSKKINKQIADNNSDITPEFKENLLDNLQNLFKE"
     gene            3341..3829
                     /locus_tag="KB969_002649"
     CDS             3341..3829
                     /locus_tag="KB969_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBB6870568.1"
                     /translation="MTDKTIKELADILGVSKDKVKYQLRKLPSNFTYKKGNITYLKKE
                     AVTTITKVLSGNESGNLPSELPDSLPTDYLLKEIETKNNHIEEKDRQIEKLQIALETQ
                     QKLLDQQQQLTLQANQQIKKLHEQLQLTYAEESSEKEPLSVTEETQKGQNKEKKWWQF
                     WQ"
     gene            4125..4406
                     /locus_tag="KB969_002650"
     CDS             4125..4406
                     /locus_tag="KB969_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870569.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4408..4824
                     /locus_tag="KB969_002651"
     CDS             4408..4824
                     /locus_tag="KB969_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870570.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5438..>5779
                     /locus_tag="KB969_002652"
     CDS             5438..>5779
                     /locus_tag="KB969_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBB6870571.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2154 a          980 c          948 g         1697 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcccttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tttctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgcgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaaatagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaact cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctcgaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtgt gttttgtaga aagggacctt atagtcactt tcacattaca aacgatacgt
     1501 ccataggacg tatcaaaagg gtgggactta tgagcaaatt aaagcaaaat ttggctagca
     1561 atccttctaa aaaatacacc tattgatcag agtcaaaata aatcagtttt cgagtgagcg
     1621 aatccaaatt tgcaactctg aagctttgca aatgagtgtg ccggcttccg taaaagtcta
     1681 ggtaacatta gtcgatatat acatagggct ctaatttgcg ttttaaggcg ttttaaacgt
     1741 tctggtatgt aattatacca aagcgacttt aaaacgcctt aaaacgaatt ttagaggttc
     1801 tgtagaacgt tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg ctttaaaaac
     1861 aagataaggg attttatcta gacttgtctt aaaacgccgt agatgagcgc tcagagcttc
     1921 taaaaggact ccttacgaac tgtttttaag caaaggagcc tttaggcgac tgcgcagttt
     1981 aatgtgagag cgtagcgatc acacctttaa agcgaccgta gggagcagat tcccagttta
     2041 ggaaatttcg cgaacctgtt tggagaaaaa aagtaggaaa attttaggcg ggaaattttg
     2101 cccccctctt ttataatctc ttttataacc tctttttaaa cctctttacc gtcggctgta
     2161 tccttactct cccaaggtgt gcagaatctt ttaggggtct ttttgtctgt ttttaggggt
     2221 ctttttgtct gtttttaggg gtctttttgt ctgtttttag gggtcttttt gtctgttttt
     2281 aggggtcttt aattaggggg ttgaccccca ttagaaagct ctttataatt ttgttaagta
     2341 gttaatcttg aaggaggatt ttatggcaaa tgaaattgtg aaataccacc atgaattaaa
     2401 tacgattcct ttacgcaaat ttacgtcagt agaaatgaat ttattcttct ctataatatc
     2461 tagaatgcgt gatgtaggcg ataaaaaagt acaatttaca ttcgaacaat taaaagattt
     2521 aagcaattat aaagcaactg caaatgttcg attcatagat gatttagaaa caacgtatga
     2581 caaattaatg gatttacgtt ttggtagaag aagtgctgac ggtttgcaac gtgaacgatt
     2641 tgttttattt aatcaattta aaatcgatgg aaaagctgat attccttttg ctgaaataca
     2701 agtccatgag aaagccttac ccttacttaa taatcttgaa gaatgggttc gatattctct
     2761 ccaacaattc aatgaattag aaagcagtta ttccaaaacc atgtttagat tattaaaaca
     2821 atacagaacc aaaggaattg ccaatttttc aaaagaagac tttcatgaat tacttgatat
     2881 ccctaaaagt tatagagaaa gtgatataaa taaaaaaatt ataaagccta ttcgccaaga
     2941 actaaccgca atcttcaaag gtttgacaat ccaaaagaga tacggaaaag gacggggaaa
     3001 gcctgtcatt ggctatcaat ttacatttaa acctgagata aaaaaatcag acgactttaa
     3061 caaacatgct ccaaccaaag aagaacaaaa taaagctttg gaactagcta atcaacaggt
     3121 tcaatctgaa aaagaaccta cttcattaca agaaaaaatc aaagaacaaa aacgaaaatt
     3181 agaactttta caacagttag cagaattaga aagaaaacaa aataccccaa gtaagaaaat
     3241 taacaaacaa atagcagata acaattccga tattacccca gaatttaaag aaaacttact
     3301 agataatctc caaaacttat ttaaagaata aggggttttt atgacagata aaactatcaa
     3361 agaattagca gatattctag gtgtttcaaa agataaagtg aagtatcaac tgaggaaatt
     3421 acctagtaat tttacctaca aaaaaggaaa tattacctac ctgaaaaaag aagcagtaac
     3481 aacaattaca aaggttttat caggtaatga atcgggtaac ttacctagtg aattacccga
     3541 ttcattacct accgattacc tactcaagga gattgaaact aagaataatc atattgaaga
     3601 aaaagatagg caaattgaaa aacttcaaat agctttagaa acgcagcaaa aattactcga
     3661 ccagcaacaa caactcaccc tacaagccaa tcaacaaatc aaaaaacttc acgaacaact
     3721 ccagctaacc tatgcagaag aatcttcaga aaaagaaccc ctttctgtta ctgaagaaac
     3781 tcaaaaagga caaaacaagg agaaaaaatg gtggcaattc tggcaataac ccaacaattt
     3841 ttattcataa aaattgttgg gttactttct ttttttgctt ttacaagcat agcgacatga
     3901 tctcacgtcg ctatttttta aagagcataa ggaaacgcgg tatcactttc ttacgaaagg
     3961 tgctaggtag gctgtgccta ccacgtttct aagaaaaaaa tttgctatca ctttttcgtc
     4021 attgtggata gcttatgtat agtgtttcgg caaaaaacag ctatacaaat actatatttg
     4081 tatgatatac ataaattata cacaaatgcg aaaggaattc ttctatggac attttagttc
     4141 ggaatattga tccaaaagtt atttcagaaa tagatagacg ttgccaagaa ctcacaacaa
     4201 aaactggcaa aaaatggagc cgtaatgcgt acctaaaagt tctaatcgaa aacgattttg
     4261 accaggcact taggcattac aaaaaagatc aattcgattt attactcgaa aaatttatcg
     4321 atatacaagc aaaaaatact gaaacattga acgactatgt tcatacaaac aaccaactca
     4381 ttgaaacact tatcggagga atataacatg agaaaaactt ctgttcaaaa acacgttacc
     4441 ctttatccca gtcacattga cgttttagat tccatcatcg aaaaaaatcc agatatcaat
     4501 aactactcgg aagccattcg ttttctatgt atgagttatg aacctaatac taatacgaca
     4561 actaccagca accaagcaaa actaaatgcg atgggaaaag aaatttctat tatgtccgaa
     4621 atcattgcag aatttgctga tttatatcta aaagatactg gtgttcttat cggtacaaat
     4681 tctaaagtat atcaagaagt gaaagaaaaa attgaaaatc aactcaatcc ctcccgacga
     4741 aatcaaccca aaaatcgtca aaaagaaacc aatcaaacat tcacttctag aaattttgac
     4801 ccaacaaact ttctaaaaag atgaaaaaga aaccgaaaat tttttctatt tctcagtttc
     4861 ttttttaggg ggcagtcttc cagcaagatt tgcaagttac cggtaacttg cacaaaaaaa
     4921 gaaaaatccg cttgtgcgaa tccttctttt tgcattttgg ggcgctgccc caatctccaa
     4981 atatcggtta tttaatagcg tggtaactca aaaaaataga acgtactctg aaataaaaaa
     5041 agactgctct aacgagcagc caataaaaaa taatgagcgt ttattcttga aaaagcagcg
     5101 cgcttatgaa gcgctgccaa aaatttacca tattttatga aaaataacaa gtttctaaaa
     5161 aggaatcggt taagattcac aaagaatcgt aaacagacaa tagcggaaaa tcaagcttcc
     5221 gaacgtacct tttagctaga ccaatgaaaa atcacaaagt gagcggctgg atcggttggt
     5281 agaggggcta cttggcatag tgtacattat gttaactaac gctataaata acgattatgt
     5341 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     5401 attataggtg tataccactt aaatttaaca caaaggcgtg attattttga aacccaaaaa
     5461 gaaaatttat ctaggtctcc tcttttcctt gatgattgga atttttagta taggaattac
     5521 aaatacctat gcttcagaaa attctaattt caatatcaac tcccaaccaa ttgaagaaca
     5581 agcaattaat tttgcgaaaa ctgattttga acactccata acttcaattc ttttaatgga
     5641 aaataacacc gaaactgata ttaactatac tcttggttcg ccatttaaaa tgctcgatgg
     5701 agaaaatacg gcaaatagtt ctattttctt tccagtattt tcagacgctg ataatacgat
     5761 taaatatatt tataccgtc
//
LOCUS       DADVXV010000122         5679 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.126, whole genome shotgun sequence.
ACCESSION   DADVXV010000122 DADVXV010000000
VERSION     DADVXV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.126"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(240..606)
                     /gene="ssrA"
                     /locus_tag="KB969_002653"
     tmRNA           complement(240..606)
                     /gene="ssrA"
                     /locus_tag="KB969_002653"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(777..1550)
                     /locus_tag="KB969_002654"
     CDS             complement(777..1550)
                     /locus_tag="KB969_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBB6870572.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1694..2044
                     /locus_tag="KB969_002655"
     CDS             1694..2044
                     /locus_tag="KB969_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBB6870573.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2025..2741
                     /locus_tag="KB969_002656"
     CDS             2025..2741
                     /locus_tag="KB969_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6870574.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2741..4189
                     /locus_tag="KB969_002657"
     CDS             2741..4189
                     /locus_tag="KB969_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6870575.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4260..4769)
                     /locus_tag="KB969_002658"
     CDS             complement(4260..4769)
                     /locus_tag="KB969_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870576.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4759..5484)
                     /locus_tag="KB969_002659"
     CDS             complement(4759..5484)
                     /locus_tag="KB969_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870577.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1936 a          984 c         1120 g         1639 t
ORIGIN      
        1 gtttttcctt ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt
       61 ttgtaaagta ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt
      121 tttgaatgct attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa
      181 atgctcaaac ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac
      241 aatggagacg gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt
      301 catagtcaac tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc
      361 gctagtctga tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa
      421 gttaggaccc ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta
      481 ggcagctaaa gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt
      541 tacgtagacg taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac
      601 gtccccgtta gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat
      661 tgggataaat tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt
      721 tcttaagaaa aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa
      781 atcagatcaa aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata
      841 aaggtagaaa gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa
      901 gcttccaaca aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc
      961 agctgaagtt ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact
     1021 gtatcgatcg agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag
     1081 tattcgtcac ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct
     1141 aaaggatcaa tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg
     1201 ctatgaccgg tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac
     1261 tgtacatgat catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct
     1321 tcgccgtcta ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct
     1381 tccatgatag agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg
     1441 ttttctttta atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct
     1501 agtaatgttc catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact
     1561 ccttttttat tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg
     1621 aagaattcct gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt
     1681 taggagggaa agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct
     1741 ttttcggatt ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc
     1801 cgcaaaaaca gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct
     1861 tatgggctta ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta
     1921 ttttctgatt gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga
     1981 aaagaaatta cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga
     2041 ttgaagataa tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg
     2101 aagcaacttt caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac
     2161 attgggatat gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa
     2221 gagagatccg caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg
     2281 aaagcgatca ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca
     2341 gtcctctgac gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag
     2401 caagagaaga agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga
     2461 tgaatacgaa aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta
     2521 aagagttcga tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc
     2581 agttgcttga attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc
     2641 atatcaagaa attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt
     2701 ggggagtcgg ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca
     2761 actcttagct ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac
     2821 acaactgaca aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga
     2881 atcagttgaa aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca
     2941 ggcgtttcaa aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt
     3001 tatatttatc gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt
     3061 taccttaaca gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc
     3121 gaataaaaat attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt
     3181 gaatcatgaa ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag
     3241 cgttcgtcca attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt
     3301 tattgccagc tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc
     3361 gacgaaagaa gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga
     3421 atttgatgag ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc
     3481 agaaattgaa gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat
     3541 gagaacacct cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc
     3601 tgaaaatcag cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg
     3661 tttggtgaat gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat
     3721 taaaaaattc aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc
     3781 agaagcagca ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga
     3841 ttatgaccga tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga
     3901 aaacggccaa atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga
     3961 agatacggga attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa
     4021 agtagatcct tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt
     4081 gcagcaactt gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg
     4141 aacaaaattc gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg
     4201 tataaaagat catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt
     4261 tagcccgcgg gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta
     4321 aagagtaaga taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct
     4381 tggatctcca atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg
     4441 gaaagcaagg catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc
     4501 gcacaattaa gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt
     4561 ttgatttctt tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac
     4621 atcggccaat ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt
     4681 ttcaagtgct ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt
     4741 tcagcatgaa tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg
     4801 gataaaaaaa gtgaaaggga atagactaag aatgagacag catccactga gcccaataag
     4861 agtttgggca aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt
     4921 aaaaaaagtc tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg
     4981 gatatctggc agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc
     5041 ataaactgac tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg
     5101 aaagaacagc tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg
     5161 ccaattgatc aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag
     5221 gaaggcaaat agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc
     5281 taaagccgga agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac
     5341 ttgattggct aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc
     5401 agaaaagctt gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc
     5461 agtagcatag cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata
     5521 tgaataaagt atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta
     5581 aaaagcaaga ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa
     5641 cactgtttat tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DADVXV010000123         5545 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.127, whole genome shotgun sequence.
ACCESSION   DADVXV010000123 DADVXV010000000
VERSION     DADVXV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.127"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..333
                     /locus_tag="KB969_002660"
     CDS             <1..333
                     /locus_tag="KB969_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBB6870578.1"
                     /translation="NRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRL
                     ESIYNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQ
                     AFERILTI"
     gene            614..1834
                     /locus_tag="KB969_002661"
     CDS             614..1834
                     /locus_tag="KB969_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBB6870579.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            1831..4551
                     /locus_tag="KB969_002662"
     CDS             1831..4551
                     /locus_tag="KB969_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6870580.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            4535..5479
                     /locus_tag="KB969_002663"
     CDS             4535..5479
                     /locus_tag="KB969_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBB6870581.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2062 a          893 c         1097 g         1493 t
ORIGIN      
        1 aatcgtcaat tgaaagctaa tatatttaac catttgaaaa agatgctaaa tgtgtctgtt
       61 actgaatcgg cacctgtaaa tattgaaatc gtacctcaaa atgtatctaa aggtgtggtg
      121 tttgatcgtt tggaatcaat ctacaattta aagaaacctt tgagaatcgc gatcggagat
      181 agtttaaatg acttatctat gtttgaaagt gcagatatta gttttgcaat gggaaatagt
      241 catcaagaaa tcatgaaaaa agctgattat gtcactgttt caaatgataa agacggagta
      301 tctcaagcat ttgaaagaat tcttaccata taaactaatt aaggtagtat agaacataga
      361 attctaaata cggaaaaatg gagcataaat tccagtacaa atagtacttc ttcagtgtca
      421 aacgaagcga atataacata gatatttagg attgtgacaa aaatcatgtc acaatctttt
      481 tttcgaataa acttattttt tgaagtcggc catttatcgt aatttctttg cataatacga
      541 acaaattttc ggttattgat gaaaaaaaac attgaaaatg gtatgataaa agaaaaaaag
      601 gaggaaattt ttaatggtga aatttatcca tgcggcagat ttacatatgg atcggtcatt
      661 tgaaggactg acaactcttg ataaaactgt acaggaaaaa ctattgaaga cgaatctgac
      721 cgttttatca aatatcattg aacaggcaat aataaataac gttgattttg ttttacttgc
      781 aggagataat tttcatcaaa atcgtccttc attaaaaata cagaaacatt tttcagaaca
      841 gatgaaacgg ttagaaaaga accatatacc tgtatttata atattcggaa atcatgattt
      901 ctatcaaaaa gagcggtatt ggttctcctt tcctaaaaat gtccatttat ttacatccga
      961 aacggtagag acaaaaaaaa taacgataaa aagtggagaa actgtctctc tcagtggatt
     1021 tagttatcgt caaccgtgga ttcaaaaaga caaagtgatg gaatttcctt ctagagaact
     1081 cacagattac catattgggt tgtaccacgg ggaacctggc gtctctcaaa aaggaaacta
     1141 tgctcctttc caaccctcaa agatgcaaga aaagggatac gattattggg ctttagggca
     1201 tatccatgtg ccaacggtct taaatgaaaa gcaaacaatt gtttatccag gtgcgcctca
     1261 aggtcatact aaaaaggaac aagcttctac atctattcta ctagttgaat taagtaaagg
     1321 aagttgccaa atacatccga ttaaagtagc agaggtctat tggaagacaa aggaaatatc
     1381 attgaggaaa gcaagaacga caaaagaggt cattgttcac attcgtcagc agctttcaaa
     1441 agtagaggat ggatttagtt taattgagat aaaattaaaa gattatgacc atctcaatac
     1501 agatgttttg gaacggatac aatcaggaga gctattagac tatttgttag aggaattctc
     1561 agataggata aatgatttct ttatttggcg tatttctctc atagagaata ctttttatac
     1621 gaagacccca cttgctgctt ctgctaaatt gatggaacag ttatttcaat actatcagac
     1681 acctcaagat ttccaacaaa ttttaaatga agtatatagt catcaagaag cggctagaat
     1741 attgagcgaa ctgccggaat atcaagaaga aacacttgaa aaagccaagc agctgcttaa
     1801 tcaagatttt ttatttgagg aggatcagga atgaagattt taaggatcga gattgctgct
     1861 tttggaaaat ggcgtcaaaa aagttttgac ttttattcag gcaatcagct gatctatggg
     1921 ggaaacgaag caggaaaatc aacgatttat caatttattc aagcaatatt atttggtttc
     1981 ccttcaaaag gccgtaaaaa aaaggattat acaccaaaag acggctcagc ctatggcggc
     2041 aaaatatggc ttaaacatcc tgtatatggt gaatttgctg tcgagcgcta caagcagcaa
     2101 aatcgcggaa aatcgaaggt gtggctgggg gatcaagtgg gaagtgatga gttactagaa
     2161 aaactgatcg cacctttgac gaaagagtta ttccagcagg tatttacttt ccagcaagag
     2221 cagttgatgg aactagatca tttgagagaa aaagagctac atgatgcgct gatttcttta
     2281 ggcatcacgg gcagttctca agtattccaa aagcggcaag aatattatca gaaagcacaa
     2341 caattattca agaaaaaagg ccaaaaatta ctaatcaatc aaaaattaaa tgaatggaaa
     2401 gagctgcaag aaaaaattca tcaaaaacaa gaacaggaag cttattttgg caagttgatc
     2461 caacaagaac aggaatacga gtcgcaacag cagcagttat tggcacaatt aaaagaggcg
     2521 aacaaacaat tttcattagc cagacagcaa gaacttaatt tttctttata tgaagaatgg
     2581 caatctctca aaaaaaacag cactacaggt cttcctgatg agcaacttct tttagatctg
     2641 gagtctttct ccaaacggta tcagcaaaca aatgagcgtt tggaagaatt agaagcaaca
     2701 ctggaaaagc atagcgggat ggatcagcag tcagccagat attattttta tttagagcag
     2761 gagcaggaac taaaagatct ccagcaactt caatttacag cggaacaatt aaacgaagaa
     2821 tggcaaagat tacaaattga gactagagaa acaaattcag aattgaagat tttggaacaa
     2881 aggtggcatt ggcagaaaaa tccgttaccg gaagaatttt tatatgaaga agaatggaag
     2941 catcttctgg ctgaagaaag aaggattgct gatctagaaa gccagatttc tgtgcgtctc
     3001 caaatagcta aagaacagca agagatgatt gaagcagaag tgaatgactt ggaagagacc
     3061 tatccagcat tattacaaaa tcagtcagag atagcaccag tctcttcatc taaaccgtat
     3121 atgctgatgg ctggcggagc aataatcatt gcaggtatat ttgtaccaat gcccttgaaa
     3181 gtgatccttt tactaattgg tgcaggcatg attggctatt tcttctacaa aaggcaacca
     3241 aaaattaaaa ctaaaaatga tttctctgag ataaaaggaa tgtggcaaga aaaactagga
     3301 caacttgatc tagccttagc tcaattagct gaagcagaag aaaaacaaaa gagaactgga
     3361 gaagaaaaac agattcttca gcaagaagta tatcgttttg cggatcatcg gcacttagga
     3421 aagatggata cgctcaaact catgaaagaa tatggacagg aagtcataga ttatcagaaa
     3481 ttatatggcg tatttgagcg gaaacataaa agagaacagg aaatacaaga aaaactacga
     3541 caaatcgacc aaaaatttga gtttgttaaa gaatggttac cgatacaaga taagacaatt
     3601 tcagaaaaaa tggtattgct ttcccgtttt atacaagaga tggaacagat gaaatttgcc
     3661 agaagctatc agcaaaatac tttattgaag caagaaatca atcaattgaa aaagaaacaa
     3721 aaagtatgga tacaagaata cagcgaacaa ttgactcaag caggcttatc ttatccttcg
     3781 gaagtacctg tctttttaca aaaagccaaa caagccgaac agcagatgaa aagatacaat
     3841 gaattatcgg aaatgcttac tccactattt cctgaagagc tgacaaaaga gaaattatct
     3901 gtaagactgc gccaactgaa agaaaagcaa tcccaactcc agcaagaaga aaaagaagca
     3961 agtgaaaatc ggcaacgact ccaacttcaa gtagaagagt tgcaaagaga cggcacattg
     4021 gacgaacttt atcaacaagc tagccggcaa aaagcaaaat tacaggaatt actggaggaa
     4081 tggggagcac ttgaaatcgc cgggacattc ttaggtgatc tttcaacaga gatgagtgaa
     4141 agacaattac cccagttgtt aagagcagca ggtgattatt taggtatttt aacaaaagga
     4201 aattatcaga agatattact gaaaaatgat acactgactt taacagacgg atatacagaa
     4261 tttcccatct atgagttatc tacaggtacg aaagatcagc tgattatggc gatgagattt
     4321 gcttacctct cattagaagc taaccgttcg atatgcccga tcatcattga tgatggctgg
     4381 cttcattatg atcatcagcg aaagtatcaa ttagctgaac ttttagctaa atttggagaa
     4441 aagtatcaaa taatttgttt ttcttctgat aaagaaatgg taagctatta ccatgagatg
     4501 aaccaaatcg taaaacaatt agaaggagca aataatgaaa aaaattcgtg atttagtaat
     4561 cgatgagcag tttgaacaat ttgtcctgat caaaagtgca gatgtaagaa tcgctaaaaa
     4621 cggaaaaaaa tttattgctt ttactttcca agatacttca ggtactatcg atggtaaata
     4681 ctgggatgct tcggaggagg aaatcaataa atttacagcc ggcacagtcg tttttctaaa
     4741 cggtaaaaga gaggtttatc aaggaaaccc tcaagtaaag attcttcata tgcgcttaac
     4801 aagggtagat gagccaggag agcctagttt atacatggaa agagcccctt tgaagaaaga
     4861 agaaatggaa gaagaaatca atcaattgtt gtttgagatc accaatgcgc attggaatcg
     4921 tattgttcgc tatctactta ataaatatca aaaacaattt tttgagtttc cggcagcaaa
     4981 aagaaaccat catgcatttg ccagtggatt agcttatcat actttgacaa tgcttcactt
     5041 agggaaatca atcgccgatg aatatcctga gctgaatcga gcattgttgt atgctggtat
     5101 cattttgcat gatttaggaa aggtgattga actttccggt cctatgtcga cagaatatac
     5161 gcttgcagga aatttgatcg gtcatctggt attgattgac gaagaaataa ctaaagcctg
     5221 tcttgcgttg aaaatcagcg aagctgacga agatgttctc gtattacgtc atatggtttt
     5281 agcacaccat ggcttattag aatatggctc acctgtacgt ccaagaataa tggaagcaga
     5341 aatattacat caaatcgaca atatcgatgc ttcgatgcag atgatgttga cttcgattcg
     5401 tcaaacagaa ccaggaaaat acaccgatcg gattttcggt atggacaacc gaagtttcta
     5461 tgtaccaaaa gatttatagc aaaaatttat ttttttcatt caaaacaaaa aaagcgagac
     5521 ataagtcttc gctttttttg ttttc
//
LOCUS       DADVXV010000124         5525 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.128, whole genome shotgun sequence.
ACCESSION   DADVXV010000124 DADVXV010000000
VERSION     DADVXV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.128"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..611)
                     /locus_tag="KB969_002664"
     CDS             complement(<1..611)
                     /locus_tag="KB969_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870582.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQ"
     gene            complement(759..1301)
                     /locus_tag="KB969_002665"
     CDS             complement(759..1301)
                     /locus_tag="KB969_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBB6870583.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            1436..1825
                     /locus_tag="KB969_002666"
     CDS             1436..1825
                     /locus_tag="KB969_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870584.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1829..2593
                     /locus_tag="KB969_002667"
     CDS             1829..2593
                     /locus_tag="KB969_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBB6870585.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIQLMEEASTFLAKNLIKKYK"
     gene            2722..3669
                     /locus_tag="KB969_002668"
     CDS             2722..3669
                     /locus_tag="KB969_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6870586.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3799..4539
                     /locus_tag="KB969_002669"
     CDS             3799..4539
                     /locus_tag="KB969_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870587.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4830..5498)
                     /locus_tag="KB969_002670"
     CDS             complement(4830..5498)
                     /locus_tag="KB969_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBB6870588.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
BASE COUNT         1946 a          917 c         1073 g         1589 t
ORIGIN      
        1 ttttgtttgt tttttctttg ccacataaat acacctagac tgacgatgaa gagcatatcc
       61 aacagatttc ctgcgacttg gatcgtcgaa gggttggtca gtggcattaa agcaaggaca
      121 aaaaaggaaa acaagctgta aataaaacag gtgacaggaa ctaatcgaaa gaagagcgga
      181 catttcaatt ggctaaaaat gagtgaaaaa ataaaataag taaaaatgga taaaatcacg
      241 actaaaccat tcatgataaa gaagaaaagc gtattgtgat taaacgaata aaaaagaatt
      301 gctaaaaaag aaaacgtttt aaatgcaatc aatacgcttg aagcttcgtt taacgtacca
      361 ggatgtcgat gaaaaaaata ggcaccgaaa taaacagaaa acagtaagcc gcaaagagaa
      421 gacaaaatca aaaaaaacgg attttcttcg gcttctgtga tatcagaatg atccaaaagc
      481 aaccagccta atgcactaga aggcgcatgt gaggtcttaa ggtatgaata acatagaaaa
      541 aataagatcg tcaaagttgc aaaaaaagag cctaaatgta aaaaattagt ggttctacgt
      601 tgaatttcca taatatctcc aaattaaatt gataagtata taaagtataa taacaaattg
      661 atgagtatat gtcgatgttt tttaatcaaa ataataaata aaaactgtct aacatttaaa
      721 atttaattta gatattagac agtttttaag tttgtgagtt attttccttg tcgttttctc
      781 acttttttag tccagaaacc acctgaaata tattttggct cataagaaat gataaaagca
      841 cgctcttcga tttctttgat caggcgatac agttcacgtt cgctttttct aggagaaagt
      901 atttcgagaa ctagccgctc accttccagc cccattgcag aagtctgtgt cacaccataa
      961 ccgtgttctc tcagtatacc cggcaaactt ttatcttctg cgctatttgc tggcaaaatc
     1021 gttgtgacca tgatgtatcc taatgccaat ttgtcttcaa tcaaaattcc gacactgata
     1081 cctactgcgt aacctaacgc atagacaaat aaattcagtg gattatctaa acgatctaaa
     1141 acaagggata agccgacgat ataaatcgtg atctcgacca tactgacaag tggagcaatc
     1201 agtcgatagc ctttcattgt caacatgaaa cgtaacgtgt tcagagtgat ataagcaaaa
     1261 ttaatgagga agatcatccc caacattttt ggatcaatca tttgtaaaac tcctttcatt
     1321 tatataacaa caatatcaaa aaaaatcgta agtgaagaaa aattgaaact ttatacatac
     1381 aaaaaaatga taaaatgatt ataatagaat tataaagata ggttaggtga ttaaaatgaa
     1441 aacggtcaat cgtgtgtttt gtgccagcca cgtgctaagt ctccttctca gtatatactt
     1501 aggtgtctat tcgattcaac agccaattga ggtagagaac attgtttttc agatgtcgct
     1561 gacagatggt ttaattttaa gcgttttttt ctttttgata ctgtttattg gtaatatttt
     1621 cggtagcgtt gccagttttt tgaatttttc tatttatcca ctcctttcgc tagcattagg
     1681 agtggtggga ctttgttctc tgtgcttatt tcccgagcca ttcagtcctg catttatatt
     1741 atttggtaca ctgaacctgt tccagacaac tgttggagca tggttgctat ggcgatcagg
     1801 aaatttaatg aaaataggtg agtaacaatt gaatccaatt atattgaaac gttctgtcca
     1861 tcatattcca gtgttagaag ttgttctgaa agaattaaga gaggaacgta ttcccgttgt
     1921 catctattat cacggatggc agacaagtaa ggagttagtt ttgacgcaag gaagaaaaat
     1981 tgcgcagcag ggcattcgtg tgatcctgcc agatgcgatg aatcatgggg agcgcaaaca
     2041 gccggtttct tctattccat cctatacatt ttgggatagt atctacggaa atctgtttga
     2101 atttgacaca cttatcaagc atttagaaaa aagaggtctt ctacatgatc agcttgcagt
     2161 tggcggggtt tcgatggggg gaatgacaac atgcgccttg ttggctaaac atcctcatat
     2221 agtagcgggc gtgtgtttga tgggttcccc tgcacctttg gaatatggaa aagaaatcgt
     2281 aaggcgcgca tcggaatata attatgtcgt accaaaagac tattttgatt tgatttcatg
     2341 ggttaagagc tatgatttgt cattgcagcc ggaaaagtta gctggacgtc ctctgttctt
     2401 ttggcatgga caagctgacg aaaaaatccc ttatatacaa acggaacgat ttgtagaaaa
     2461 aaatcggcat aagtcttacg gaaaagaaat tgtttttcgt tcctcaaaaa cacagcgaca
     2521 tatggtacaa atacaactaa tggaagaagc ttccactttt ttagcaaaaa atttgataaa
     2581 aaagtataaa taattgaaac ggaaaatcac tcatgacgat agaggatttt ccgtttttta
     2641 ttttgggcta taataaactc tgttaggaaa atttggtata attgatagta agaatgacaa
     2701 catgttagaa aggaagagag catgcccact ttagcagatg ttgcaaaacg tgccaatgtt
     2761 tcaaaaatga cggtctctcg agtcatcaat catccggaac aggtgactga cgaattgaaa
     2821 gagttagttt tctcagcaat ggctgaactg gattaccgtc caaatattgc tgcaaaagca
     2881 cttgtcacga atcggtcgca gatcatcaaa ttatttatac tggaagaaat cgacacaact
     2941 gagccctatt acatgaattt gctgatggga atcgctaaac ggatcggtaa agcgcattat
     3001 tctctccaat tagttacaaa tgatgccttc gacgtcggtt cttgtgatgg atacatcatc
     3061 acaggtgtca gaaaaaaaga cttcgattgg atcgaccgtt tggaaaaacc agttgtcttg
     3121 tttggggaaa attctgaagg atatgattat gtagacagcg ataatgaata tggtacagca
     3181 aaagcaacgc aatatgcctt agaaagagat tatcaaacga ttatttatat cggtatcgaa
     3241 gtggacgagc cttttgaaat ttcaagggaa actggttatt tatctgtgat gaaggaagtt
     3301 gatcttccta gtaaaatctt gcggtttcca aatcattcga cagaagtaga aagatatatg
     3361 acagaaaact gggcagattt tacagataaa acttgttttg tatgtagttc agatcggcta
     3421 gcactaggag cagtaagagg gattataaat gctggaggac acttgcccga agaatttggt
     3481 gtgattggat ttgatggggt atttttagac caaatcagtt cacctaaatt gacaacgatc
     3541 aagcaagata ttatacgtat gggtgaagta tgtggagaaa tgttgttaaa aaaaatagaa
     3601 gaaaaagggg cgagtcaagg ttatcgtcgt ttttttcctg aactagttat cagagagaca
     3661 acgaattaag tcttattact atatatatat ttatgaaatt catcgctatt ttcttaaaat
     3721 aatcagcgca ttgctactga aaacaatgaa tctgtgctat tattgagaaa agttccattt
     3781 ttgagaagga tggtttgaat gaaagaaatc agacgaaaac atttccgttt tcctgcgtac
     3841 gatgatgagt taggcgtaaa attaaccaac gacaagaagc gagtattatt tgacggacaa
     3901 gaagatcttt tgactgaaca gaatcagtcc ccgtttgaac agatgaaaga atttcatttc
     3961 acgaacacga acaccgagaa aatccgtcgc aagcgtcgtg caacaaatgg attgaagtca
     4021 gctccgcgta aggaaaattt ggaaaagcat aaaggaaaat taccggatta taccggccat
     4081 taccaatcag aaatcacatc gacaggacga aaaaaacttt ttggtgattc ctctcgttct
     4141 gtcagacaaa gtgaaacaag gacagagtcc aagcatacta cacgaaacgc atctgttgac
     4201 acgaaggtgc gggagcgttc ttattttgtt cctaaatatg tacccgcatc gattatccca
     4261 gaccctagag aaagcaaaat ttctgaggat catttaatcg aatcgatgaa aaaaacggat
     4321 gactcttatc tgttgttcga tacagaaccg acgccgtatc aagaaaaaag aaatggtgag
     4381 ccgtctgtac gaacattcaa tcgaacaaaa acgttagagg aaacaaagca gtcagaagaa
     4441 aaaaaatcga aaaaaagcca tggtatctta gaacgctcat tacaaggatt gatcgatgat
     4501 caaggaaact ctttgggaga aaatagctat tttaaataag tgatatacaa atttatattc
     4561 ggctacagtt ggaaaggaaa cgctgcggcg tttccttatt ttatactcta tccgaaagtt
     4621 tatatcgtat cctcaaattt ttttgagttt aagcgaattt tttctcccaa taagtaagaa
     4681 aataatggca aaataaaaaa acaaactatt ttcgcagatc gtttgcaaaa atagtttatt
     4741 tttttataaa gaagatttta ctgaataata tcattttagt ttacataatg atatttctgt
     4801 aaattaaata aagtagtgaa aaataagaat cagtgctcta actgttcaag aggatcaagt
     4861 ggttcaaatg tttctgtagt ctgttttgct tccaattggg gcaaaacaga tccaatttcc
     4921 agatacttca ctttattcaa tgtataagat agaatagaac agctaagtaa tgtatacaga
     4981 aaatgtgtga gatccaaata aagcaaggag acaactaaaa taccaaaagt aatcaagaaa
     5041 agacttttgc caatcttaat atgaaaatat ttttcaatgg cttgataaat gatatctgtt
     5101 ccgcctgtgc ttccgccgaa tcgaaagacg agaccgcaac caatgccaga aagaatacct
     5161 gtcatcaaac tattgatcag tagactatct acagcaaaat gtatatgaag gctctcccat
     5221 aaatgtaaaa agaaaactag cgcaaatgtt ccgacgatcg tccggagaaa agcgtgtttt
     5281 ccaaaaagaa acaatgagat aagcaataaa ggtaaattaa aaagcagtga agtgacagaa
     5341 ggagcgaatc caaaaagatt atgcaaaagc aaagcaatac cagtaacccc accatctgcc
     5401 agcttagatg gaatattgat tcctgtcaca gctaatccgt agattcctgc gcctaaaatg
     5461 attccgcaca attctgtaaa taaatttaat tttttcattt ctagcctctt ttcttttgaa
     5521 aattt
//
LOCUS       DADVXV010000125         5523 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.129, whole genome shotgun sequence.
ACCESSION   DADVXV010000125 DADVXV010000000
VERSION     DADVXV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.129"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(26..1957)
                     /locus_tag="KB969_002671"
     CDS             complement(26..1957)
                     /locus_tag="KB969_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6870589.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="KB969_002672"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="KB969_002672"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBB6870590.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="KB969_002673"
     CDS             complement(2886..3638)
                     /locus_tag="KB969_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBB6870591.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3797..4006)
                     /locus_tag="KB969_002674"
     CDS             complement(3797..4006)
                     /locus_tag="KB969_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870592.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4017..5344)
                     /locus_tag="KB969_002675"
                     /pseudo
     CDS             complement(4017..5344)
                     /locus_tag="KB969_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1577 a         1176 c          957 g         1813 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa taaaaaacca gtcagaaaga ctggtttttt atttttttgt
     3781 ctatcatcaa gccgttttat cgttttttat tttcgcttct tgtttttttc atataaacag
     3841 aagcaggttt tctttcctta tgaagaagat aataataaag tcccatcccg ccaaacatga
     3901 ccaaaaaacc gatgactgat cgaataggaa aattaggaac aaaaaagaga cagacggata
     3961 ataatgatgc cggaaccatt attcgataat agagttgttt atccattttc ttcacctcat
     4021 attttttgta aagtaatcaa ttgttctaat tctcggtaat ctaaaaattg cacacgcaga
     4081 tgctgctcac ctttcttgac atcgaattgg atacttcgcc gctttttctt tattcgtttg
     4141 aaggtaacat cagagagtct atgtttgatt tcctttaacg gtaattctga cagggattct
     4201 gaaggaacat agattcttaa ggataaaaga tactcttgat atttttcatc tgttacctct
     4261 acttctagat attccctaat ataataacaa taagcttcga ttccattatc caaagcaaca
     4321 gtcggatcga taactttata gcacatcatg cgtgatcgat tctcgtcaac ccaaggaaaa
     4381 tacgcctgag catttagtgt tccgcgaaca cgcctttctt tataatctcc ttgttggata
     4441 tcataacttt ttgttacaaa aaatgaagca ttctttttag gaacaggttg catttgtgca
     4501 ttctgatact ggacagattg gatcgtatgg tcagtgtaaa tgtattcaac gaatggcggt
     4561 ttcaataaac cgacaccatt gtcccaagca agatgatcaa acccaagctg gtccctaaaa
     4621 taggattgaa acatttgatt gtttggcttt tgccagttaa aggggtctcg ataaagctgg
     4681 atacatatga cttcgttttc taattccttc actttttcta cttgttggat gtcgagaaaa
     4741 atcggtttag ggatgatttg atgataatag cgactataat acatttccca acacgaagtg
     4801 aaacataaac cttggtaaaa aagatcgtat cctggaaatt ggttgcaatc gactactact
     4861 tccccgtttt gttgtttcat tttaggtaaa tgttcgattt catccttttt ctcaaacaat
     4921 agccgttgag agatctgttt tgtattgtga tagataaact cgctataagc tcgcatatag
     4981 gcgaacaccc catgagcaat catttttttc tgaatgaagt ctcgaatcaa aaattgcttt
     5041 tctttgaaaa cagagataga caatacattt tttatcaata attgattatc ttccaagcga
     5101 aaactacatt cgttctcgtc atttcctaca actaaccaac tttcgtctct taccgatgct
     5161 agcattattt tttcttgaag ctttcgaaga tcatacggat ccgcttgttg tgtgaaagag
     5221 cggataaatg ttggctggat caacagacgt gtcaaaatag cccaatcgct tatttcctgt
     5281 ttttttcttc ttcatttaag tctgtgagct ggatagtcat caataattta tcttcgccaa
     5341 tcattttctc acctctttca aatcttttta taatttaatt ataaccaatg ataaagaaaa
     5401 actaaaactt tatgtcttag aaaccaattt ggacgattac atgatagact aagtaaaaag
     5461 aaacaaagag gtgtttacaa tggggttgaa atttgaacgt acagataatt tagataaact
     5521 ttt
//
LOCUS       DADVXV010000126         5476 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.130, whole genome shotgun sequence.
ACCESSION   DADVXV010000126 DADVXV010000000
VERSION     DADVXV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.130"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            324..881
                     /locus_tag="KB969_002676"
                     /pseudo
     CDS             324..881
                     /locus_tag="KB969_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            939..2978
                     /locus_tag="KB969_002677"
     CDS             939..2978
                     /locus_tag="KB969_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBB6870593.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDQYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGEKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKDDDDSATKRASELLQYLNQNYQ"
     gene            complement(3087..4238)
                     /locus_tag="KB969_002678"
     CDS             complement(3087..4238)
                     /locus_tag="KB969_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBB6870594.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVFLLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4392..4922)
                     /locus_tag="KB969_002679"
     CDS             complement(4392..4922)
                     /locus_tag="KB969_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBB6870595.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(5021..5371)
                     /locus_tag="KB969_002680"
     CDS             complement(5021..5371)
                     /locus_tag="KB969_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBB6870596.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
BASE COUNT         1986 a         1008 c         1034 g         1448 t
ORIGIN      
        1 agaatatagt aataaccttg ttaggtgagg ctcctataca aacataggct gttgcccaga
       61 aacgtcgaaa gtcgccaatg ggtaaaacag aaactgttgg attaaggctt tttccaatag
      121 ctaagaatgt tttctttacg ttgtatagtg ctaaaactcg gacgatgaga tgatgctagg
      181 tcagaattct tgttcgaaaa ggtttctgac cttttcttta tatttttgtg actgacttat
      241 ttgatgagac aaactcgctc ctcacctgac aagtggattg ctgtgtgagg aggagatgcg
      301 gtgaaaaaag atcgattggt ggaggtcgct cggattcact tctggttgca caatacaacc
      361 agaaaacaca acaagcaaaa ctgatctcta tcatgagaga ttcatatgtc gatattccag
      421 gttacggaat gaataagata aatgcagctt actcttatgg gggagttgat ttattaaatc
      481 aaacattaaa ggaaaatttc aaatttgaag ctccctatta tgcaagtatc acatttcaag
      541 attttatcga ttgcgttaat gaactgtttc ctggtggagt caagatcgat gcagaaaaat
      601 ctctagattt agatggcgta tatataaaca aaggagagca agtgatggat ggtaatactt
      661 tactccagta tgctcgattt cgggaagaca aagaaggaga cttcgggagg atcagaaggc
      721 agcagcaagt gatcaaagct atctctcagc agctgaaaga cgtaacttca atattcaagc
      781 tacccaaagc ggttgggaaa ttacttggta gtatccaaac gaaccttcca gaaagtgtgc
      841 ttctggattg tggtatggat ttcctcaaag acatatgtta gaataaacag gtataaatag
      901 tgaaataaag gaatgacaag caagagaagg aggaaaaaat gaaaagaagt gacaagcacg
      961 gcaaaaatcg aacaggcgct tatattgccg gcgcagtgat cttaatagca gctgcgggtg
     1021 gcggttattt ttactaccag cactatcaag aaacccaagc agtagaagct ggagaaaaga
     1081 cagttgagca atttgtccaa gctttgaaca agggagatta taacaaagct gcagaaatga
     1141 catcaaaaaa ggcggcaaat aaaagtgcat tatctgaaaa agagatctta gatcaatacc
     1201 agaatatata cggtgctgct gatgtcaaag gacttcagat atcgaatcta aaagtagata
     1261 aaaaagacga ttctacttac agtttttcat ataaagcaaa gatgaatacc tcattaggtg
     1321 aattgaaaga tctttcttat aaaggaacat tagacagaaa tgatggtcaa accacgatca
     1381 actggcaacc caacttggtt tttccagaaa tggaaggaaa tgacaaagta agcctgacca
     1441 cacaagaagc agcaagaggg aatattatag atcgaaatgg tgaaccatta gcaacaacag
     1501 gcaaactaaa acaattagga gtcgttccaa gtaaacttgg agatggaggc gaaaaaacag
     1561 ccaatatcaa agcgattgct tcctccttcg acttaacaga agatgctatc aatcaggcga
     1621 tttcacaaag ctgggtacaa cccgattact ttgtcccatt gaaaatcatt gatggagcaa
     1681 cgccagaact tccagctgga gctaccattc aagaagtaga cggcagatat tatcctttgg
     1741 gtgaagcagc tgctcagctg attggttacg tgggagatat cacagcagaa gatattgata
     1801 agaatccaga attaagcagt aatggaaaaa tcggtcgctc aggtttggag atggcttttg
     1861 ataaggatct tcgtgggaca acaggtgaga aattaagcat tacagatgca gacggtgtag
     1921 agaaaaaagt tctgatcgaa catgaagttc aaaatggcaa agatatcaaa ttgacaatcg
     1981 atgcgaaggc acaaaaaaca gcttttgaca gtctaggagg aaaagctgga tcaactgttg
     2041 cgacaacgcc aaaaaccggt gatcttcttg cgcttgctag ctctccaagc tatgatccaa
     2101 acaaaatgac aaacgggatc tcacaagaag attacaaagc ttatgaagaa aatcctgaac
     2161 atccattcat cagccgattt gcgacaggtt atgctcctgg atctacgttt aaaataatta
     2221 cagcagcaat cggtctcgac aacggcacta tcgatccaaa tgaagtgttg acgatcaacg
     2281 ggcttaaatg gcaaaaagac agttcttggg gatcttttaa aacaacgcgt gtcagtagtg
     2341 atgtatcaca agtagactta aaaactgctt tgatctattc cgataatata tatgcggcac
     2401 aagaaacgtt gaaaatgggt gagaaaaaat ttcgtacagg cttagataaa ttcatttttg
     2461 gtgaagacct tgatttgcca attagtatga atccagcaca aatttctaat gaagatagct
     2521 ttaactcaga tatcttgcta gctgatactg gatatggaca gggcgaactt ctaattactc
     2581 ctatccagca agcagcaatg tattctgttt ttaccaacaa tggcacactt gtctatccta
     2641 aattgattgc agataaagag acaaaagata agaagaatgt catcagcgaa acagcagtac
     2701 aaacgatcgt gccagatctg agagaagttg tgcaagatgt aaatggtaca gcacattctc
     2761 tttctgcttt agggattccg ttggcagcga aaactggtac agcggaaatc aaagaaaaac
     2821 aggatgtaaa ggggcaagag aacagtttct tgtttgcttt caatcttgat aaccaaggtt
     2881 atatgatggt cagcatgttg gaaaataaag atgatgatga ttcagcaacc aaacgagcat
     2941 cggaactatt gcaatacctc aaccaaaatt atcaataaaa aattgctttt taagtacagt
     3001 aaaaggactg tggcgttatc gtcacagtcc ttttttcaaa taaacggttt tcacgatgtc
     3061 tctttcacaa cttctttttg atttactcac acttcataaa ctttttttgt aaaatatttg
     3121 agaacaagtg gagaaataag tgtacttaat aaaatcacga taactaaagg tgaatagtac
     3181 tgtggttcga tcaattgact ttgctgtcca atttgtaaaa tgatcaaagc catttctcca
     3241 cgcgaaatca taccagcacc gaccatcaat gaactatgtt gagaaaaacc ggcaatctga
     3301 gcaccaaaat aacctccaag caatttggtc aaaatcgcta caagcgtcaa tatagaaata
     3361 aagagtagtt gttcactaaa gtcagaaaaa tcaacttcta atcctacact gacaaaaaat
     3421 actggtataa atactgcata tcctaaagcc tctacattgt ggtatacttc ttctttaacc
     3481 tttgtctgac tgacagctat cccagcaaaa aaagcaccaa tgacagagct aagcccaaca
     3541 agatccgcta cgtaagacat tcctaaacaa ataactagcg atacgatgat aatagaagaa
     3601 tttgcgtaca ctttttctgc aaatgaaagt aggaaaggcg caatccattt gactaataag
     3661 aaaataaaaa caaaataaat tagctgttca atcaaaacaa gcggtaaaga agcattgcta
     3721 gaagcttccc ccgttagaaa agataggctg aaacttagaa ctaaaacgac taaaatgtca
     3781 tctaccacag aagcacccaa aattgttgat ccttcttttg tattcactac gtttagttct
     3841 tttaatactt ctactgaaat actgacagaa gttgccgcaa gaataatccc aaagaaaatc
     3901 gcttcatttc ccgaaacttg gaatgctttg cctgtcaacc agccaaaaac aaccgggaag
     3961 atgatcccaa gcaaagcaac gaacatacca ggtcggaaat attttttcaa aagagataaa
     4021 tcactttcca gaccagctaa aaacattaat aagaacacac caatctccga aaagtcatgg
     4081 actagaatat caggtttgac ccaattcaat ccagcttggc ctagcaaaac accaacaagt
     4141 aattgtccaa tcactgctgg gatacctaat ctccgcgaga tatgtgagcc aatcgttgtt
     4201 gaaatcaata tcaggcataa aataccaata aattccattc tcatcattcc tttgtataaa
     4261 atatagcccg aacttagcat aacatacatt attgaaaaaa taggaaaata tactcacaaa
     4321 aaaaccaaca atccaaaaga tttttttgga ttgttggttt ttatacggtc tattttaata
     4381 actaaaaatg attaacgtat agtcattttt cttattctga tgaaattgat aatctcctgg
     4441 atgcccatga aaatcaaaat aaagccgaat atttggaata gaagcatcaa acttttgaat
     4501 ggattgaaca ataagacgaa tccgccaatc aacaacagaa tactactata aacactccaa
     4561 cttttagctt ttgtattcat gctgaagaac aactggaaca agctgttgat gataacagct
     4621 aatccaagaa gaatcggcag gatagaaacg attgcaggtg caaaagcata gacgatcaga
     4681 gctaagatca ggaaaaaaag accactgaac agaccgatac tccaagaacc tgttttcctt
     4741 ttaaaacggt aagcctcaaa aagattcaac aacccaagca aaacaagata ggcggtgatc
     4801 agataaccga taaaatgaaa aacagcagaa gggtttagca caatcgcaat cccagaaata
     4861 atataaacag cagctcttaa taaggcgtat ttttgaatat tttgtttaat cgtctcaaac
     4921 atataagaaa acctcctttg acttatttta acgtgaacta gtcattttac caaattaaat
     4981 gttacaaaat gagcgaagga gaagaatatc tctggaaaaa tcaacttctg aggatctttt
     5041 ccattttttt gccttttgct agctcatcga tcattttatc taaataacga atttctttca
     5101 tcaagttatc ctcgatgtct tctactcgta caccacaaac aacacctgta atcaaggaac
     5161 gtgaaggatt ggggacaggg gcttccgcaa aaaattgttc gaaagtcact tgtttttgta
     5221 gttgatattc tagttctgtt tgggaataac ccgtcagcca acaaatgatt tcatctactt
     5281 cctcttttat acgatctttt ctctccgctt ttgctacata cataggataa acgcttgcaa
     5341 aacttgtcgt aaaaatacga ttttgcgcca taatcagtca cctttctttt tttcaaatta
     5401 tttactactt atagtatata agaaaaagag aagaaaaagc gattattcaa aaaaacaaaa
     5461 aggattgtga caaaat
//
LOCUS       DADVXV010000127         5473 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.131, whole genome shotgun sequence.
ACCESSION   DADVXV010000127 DADVXV010000000
VERSION     DADVXV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.131"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(174..791)
                     /locus_tag="KB969_002681"
     CDS             complement(174..791)
                     /locus_tag="KB969_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870597.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            complement(853..1533)
                     /locus_tag="KB969_002682"
                     /pseudo
     CDS             complement(853..1533)
                     /locus_tag="KB969_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(1855..2076)
                     /locus_tag="KB969_002683"
     CDS             complement(1855..2076)
                     /locus_tag="KB969_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870598.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(2174..2419)
                     /locus_tag="KB969_002684"
     CDS             complement(2174..2419)
                     /locus_tag="KB969_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870599.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            2659..3273
                     /locus_tag="KB969_002685"
                     /pseudo
     CDS             2659..3273
                     /locus_tag="KB969_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(3643..4644)
                     /locus_tag="KB969_002686"
     CDS             complement(3643..4644)
                     /locus_tag="KB969_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HBB6870600.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(4803..5069)
                     /locus_tag="KB969_002687"
     CDS             complement(4803..5069)
                     /locus_tag="KB969_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870601.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(5059..5415)
                     /locus_tag="KB969_002688"
     CDS             complement(5059..5415)
                     /locus_tag="KB969_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6870602.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT         1691 a         1011 c          751 g         2020 t
ORIGIN      
        1 gaaaattacg tctacgtttt cctatttagt tctatatttt cattaaattt tatatttgct
       61 cttttcactt ttcggaataa attcactgtg actcttgata ccttctttta tatattgcta
      121 atgtattttc tccattgcta tgaaaataga atcaacatat ttataatatc tatctaatct
      181 attttcattt caccgcagca tcttattaaa taacgtgtaa ataagaatat aaaagttatt
      241 gaactaatta ataaagatag aatcatcgta gttggatacg tagatgaaac ctcaactata
      301 gttcttttcc ccgtaccttt aatagacact aaaccattgt cattttctat agtgctcttt
      361 ttcccattta ctttcacaac tgttccccaa taattgaata caggtaatgt gatattttgc
      421 tcatcggcat cttctactgt atagactatt ttggaattat atgctttatg agatgcattc
      481 tcccaccgat caccaacttt tacttcatgt ttctttaaat gatctttata tttcaatgca
      541 tctaatggtg catagtcata taggcctcca gttcttgagg atgtataacg tgtaacatct
      601 tttttggtca taactaaacg acctttatac gactgaattt tatgcgaata atttgcttct
      661 gttgctgcag tcacagtaaa aataataaga actattccta caaggctcca catacttttt
      721 ttgttgcttg ttttccactt taaaaacact atggttaaga ttaatgaacc aaaaagcact
      781 tgaaaaccca aggttctcgg ttctgttgcg aagtttgaaa atcaaacgcg ccctctctga
      841 actccaaata tcttaggctg ttattcccat taataccttg atttcagtag acaccgaaaa
      901 gccgaagagc gttccatttc ttcggttctt tttatatatt cctcgaatgg tctccatgcc
      961 cttaatcgtg gaagaggctg tacggagact ttgataaaat ttatttcgtc gtttaatagg
     1021 tcgatggtct tgttctatta aattgttaag atacttcaca gttcggtgct ctgtcttagt
     1081 atataaaccc acactctgta actttctaaa ggcggagcca agagaaggtg ctttatcggt
     1141 cacaattgct ttcggctcac caaactgttt atggagtcgt tttaagaaag cataggctgc
     1201 ttgcgtatcc cgtttctttc gtaaccagat atctaaggtt aagccgtccg catcaattgc
     1261 acgataaaga taatgccaac gtcccttaat tttgatatag gtttcgtcca ttttccatga
     1321 atagaaggat tgtctatttt tcttcttcca aagataatag aggactttgc tgtactctta
     1381 tacccaacga taaatcgtag tatgacaaac atttattcca cgatcatata acaattcctg
     1441 aacttcacga tagcttagat tgtaacgcag gtagtaacca acagcgacaa taatgacgtc
     1501 ttttttgaat tgtttgcctt taaaatgatt cattactctg tcctctctgt cttttttctc
     1561 aattttacac taaaatagat tttttggaaa actttgcaac agaaccgttt ttactatata
     1621 cttcttccca gaacttgtcc gtctccttca aattatctct acctctcgag ttcattgggt
     1681 ggtttgccca tttattaaac atggaatcac ctttctcata ctcatatatt tatgtcctat
     1741 ttcaattata tttatatatg cttaaataaa tttgtatcct gaaatttatt gtaatatgaa
     1801 gctgtatttt acatatagta accaaagagt taataaaata aaaagagcga accattatag
     1861 atcagctctt ttttcattgc tgtttttaat cttatctaga atcacttcaa atgtttcaaa
     1921 ggtatttaca tctaactgac ataaccaaag caagtacttc ttttctttgt aagtccaatc
     1981 aatattacgg taagaggaca ttagattatg gtaccttgct ctttgttcaa ctgaagccaa
     2041 ttcccagcgt ttttcaaata ttttttcttc ttccattatt gatccctcgc aagacgctac
     2101 ctcaaactta aataatgggc agcgaaagtc taattcctta gatctaagta tagcaaacaa
     2161 atatgaaaaa aacttagaag gtagtaaaag ttcttccgtc ttttgctttg cttctattct
     2221 taatgtgttt cgttatcggt gccctacaaa gattttcatt aattacacac tcatttattg
     2281 ttgtgtattt tctgacattt ctctcttgat caattatttt aattccatgg gcatcctgat
     2341 agttcatagg agaggagcgg ctatcagaaa tagttgcacc tatctcttga acttctttta
     2401 caacttctgg aaaatccatc catcctgctt cagctgtcaa aagtaataat ctataatatt
     2461 tatctttcct tttcaatcta agaaatcgtc accccattct ttttcttcta ttataaacta
     2521 tttaactttt agaattcaaa aaccgtttgt ctatttagag tttaccctaa atagacaaaa
     2581 atataacatt gaaaaattta gagttctaac gtatgattag ggtgtattat aaacgttata
     2641 gaaaagtagg gaataaattt gaaaattgct tatattagag tttcatccat cgatcaaaat
     2701 gaacaacgtc aaattgaaga aatgaaaaag tttggcgctg aaaaaatttt tatcgaaaaa
     2761 caatctggag cgacgattag tcatcggccg attttccagg aagctttaga ttttgtcaga
     2821 gagcaagata tttttattgt agaagccatt gatcgacttg gacgcaatta tgacgagatt
     2881 atcgattcag tgaattatct aaagaagaag aatgtgcgac ttattatcac cagtttaccg
     2941 atcatggctg aagcaattgg aaatcctctc ctagataaat tcatcaaaga cttaatcatt
     3001 taaatctcag ccatgattgc tgaacaagaa cgtactgaat cgaaacgacg ccaggcacaa
     3061 ggaattaaaa tcgctaaagc aaacggcgtc tataaaggtc gtcctaagtt atacagtgca
     3121 gacaccaaag atcctcaacg tcgccttgtc tataggagta tcgttcagga tcttgagaat
     3181 ggggttgcta tctcaaagat tgcaacagac tacaatgtga ctaggcaaac aatttaccga
     3241 ataaaaaaag aaatcgacca actaattgta tgatttcttt tttgaatcac gtaattatta
     3301 attagctttg tcatcaatac agacaatcat tttagattca tctagctaag ttgattacat
     3361 ttatgttaaa aagaatttag ttaacataaa tataattgat gcataaatcg tccttattta
     3421 aaggcattta acattgacaa cttagtataa tgtatcttat gtaaactaat aagatttgaa
     3481 ttttatttta tacacactcg ataatagatc aattttatgg tcccccgcat ttacgattgc
     3541 acaagagaaa cataaagtcg acctattagc atttcttttc aattcaaaca ttaaaaaagt
     3601 ttatacctct gctactaaaa aatgaaatta tctatttaaa atttaaaacg gtaaatctga
     3661 ttcatccaaa ttggaaaatg gatcagcctg tattggagct ttgtatttct ccataataac
     3721 agatatcttt ttttcatttt ttaaaaaata ccttttaaat ttcttatagt cctctgaaat
     3781 caaaatatag cgtgatggat actcatcaaa agaagaatcg tattcttcct ttaaaattcc
     3841 cgatttactt aatttttcta gtacatcaaa tactctatca ctcaagtaac tccttaaatt
     3901 gttatcactt tcccattgaa ctacttttct ataagttgaa ttatcagttg aaaagataga
     3961 attttcatcc ataaacgcat atattagcag caatctttca tcattgtcaa attctattgg
     4021 atcaaaaata tctaagttgt catcaaaatc tttatcagtt ccggtaactt ttttgttaat
     4081 tactgaaggt gtcttgtaag aaatagaatc taaatcaaag cgttttgatt ctaaattatt
     4141 ttgtgctttc tcaattaaat aattcacttt ttttgtgaga aaccttctga tattgtcttt
     4201 gctatatgtt ccataaaaac ccttatcttc taaagagtcc ctgtacttct taacttctat
     4261 atactcttca gccaaaactt gtggaactgg ttcatctaag aaaaaaaccc ctacctcgcc
     4321 tttgctattt ttataaaagt aatcaatttc tgctatagtt cccgatctat aattatcaac
     4381 tggagaaccc aacttatggc caaaaatcgc taataatata tcactatttt ctacaatttg
     4441 tttattaata acactttgcc cagagctatt atttatataa gtaggaatcg cattcgtttc
     4501 ccatcgaatt ggcatcaaaa ttacttttgt attatctgta ttttctatat tccatctata
     4561 tatggtttct tctacttcat tcctctttgc tgctatatca cctggtgatg ctataaatac
     4621 ttttattaga tttatggttt tcatttattg tacctttctc tttatgtctc tttaaagtaa
     4681 tttttgtata aaatttattg acttttacac tataggacaa cttttatcta tttagtacaa
     4741 aaaggcccac taaactaatt gattagttag gagcctatta caggtatatt ttcaactcgc
     4801 ttttaagcaa attctactac cagctttttg cctaatgccc tagcgatatc atcaagttta
     4861 tcgaaagata cgttatcccc tctctcaatt cgagcaatag tagattgagt tgtatgtgct
     4921 ttttgtgcaa gctccgcttg agttaggcct gcttcctccc gtgcatgata aagagcaacc
     4981 gcagtttcga gttttcttcc ttcacggtca tatgcttctg caaaatcttt gtctttttgc
     5041 ttttcttcaa tcaatttttt aatcatcatt tgtgaaccac tcctctctaa gttcttttgc
     5101 atgtttaagt tcacttattg gtgttttctc cgttttttta gtaaatccat gggtaatgac
     5161 ataccttcca ttgaccacat ggaaatagat agctctttgg atgtttgatc ctaccttact
     5221 tcttaattcg tacaaattag tgtctaattt tttcacccat ttcaaccgtt gagctactag
     5281 catcccattc ttttctgttt cttctattgt acgtaaaagc ttcgcactat ctttttttgg
     5341 taatgtttcc aaccattcta aaaattcatc atgaccatta ggtcttttaa atgtttcaaa
     5401 agatattttt tccataccca attatatcat atattgattt tatattatag tatataacat
     5461 aaaaattcga att
//
LOCUS       DADVXV010000128         5165 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.132, whole genome shotgun sequence.
ACCESSION   DADVXV010000128 DADVXV010000000
VERSION     DADVXV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.132"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(636..926)
                     /locus_tag="KB969_002689"
     CDS             complement(636..926)
                     /locus_tag="KB969_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870603.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1328..1564
                     /locus_tag="KB969_002690"
     CDS             1328..1564
                     /locus_tag="KB969_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870604.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1571..3523
                     /locus_tag="KB969_002691"
     CDS             1571..3523
                     /locus_tag="KB969_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBB6870605.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3595..4092)
                     /gene="dfrG"
                     /locus_tag="KB969_002692"
     CDS             complement(3595..4092)
                     /gene="dfrG"
                     /locus_tag="KB969_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBB6870606.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4419..5111)
                     /locus_tag="KB969_002693"
     CDS             complement(4419..5111)
                     /locus_tag="KB969_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6870607.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1667 a          900 c          859 g         1739 t
ORIGIN      
        1 ttttaaatac ttaattgtta aataccttat ttgatgcaaa agaaatctac gatagtcaac
       61 aaaaaaattt tcattatatc cagaaaaatt tttcttagtt aaggacctat ggattgcagt
      121 aatgcagaat tcgtcgaata aactgccaaa gacatacaat catattgctt ttaaaattga
      181 cgaacaagat atagattcgt ttgtctcaaa aatccaaatg ttaggtttaa ctgtcgaacc
      241 aggacgttct cgtgtgaaag gcgaggcttc ttcaatttac ttttacgact atgataatca
      301 cctcttcgag ttacataccg gtactctcca ggaacgttta aaatcctaca attccactac
      361 ctgagactag taatgactag tctcttttta tggcctctga tccccccatt gagcgaatac
      421 taatagggct tcgaattgat ctgttcaatc tttaagcaat atccctcaaa tgagtttgga
      481 aagtttagtg attcatcaca aatacttaaa tacatgtagt tatatataga ttgaggttct
      541 tgtgagcgta tgctcgtgtg ggttcaaatc ccatcgtctg catccatctt tccaaaacaa
      601 gcggctagga catttttgtc tcagccgctt gttttctagt ttattctttc atcttgtcgg
      661 accttttttc ttgggtatag acttttctca tattctacca caattttggg tttccctaac
      721 acatgatagg atctcacaac aaattgcttt ctattattat aataacctgt aacgactaac
      781 ttcatccctt cgtctacttc agctaggaag ttcaaactat gggaagcaat caaacaattg
      841 accccattta aactgaaacg gatcaacggt ctggcactaa cttgcaaagt acggatctta
      901 tctactgttc catatttttt ctccataacc ttcacctcaa taccattata cgaacataca
      961 ttccctttgt aaagaagaaa ctctgtttta tctttttgac tttttgtcta ttacctttct
     1021 taaaatcata ttggcacttc ctgcgaagat gaaggacatg tactaaaaaa aagaggcagc
     1081 agtatagatt taagtagttc agttttggag tacaaaaagt gaaaatgtaa acctaaatga
     1141 gtatcaaatt gcaactgaat ttgatactcg ttttttattg ttaaatcaac gtttgttgtt
     1201 aatttacacc acaaaatgta agttaaaatg tatataaaaa tgcgaacgtg aaataattat
     1261 tgtaggaatg caaattggtg tgttaaaatg gttacaattt actaagcaaa aaggggtgca
     1321 ttttcctatg caatttcttg agccaaaaaa taagaacgct aagtctgtgg attgggaaat
     1381 atcagagcaa gtaagggtga tagttaagca atacgctgaa tatgcagagc gtactgaaag
     1441 cgaagcagtg gatgaattct tattgaacat tttagacgat aagaagttta ttgaatggat
     1501 tgccaacaag cgaagtaata agcggattgt tgaaaaaatg ggtatcaaag atagagtggg
     1561 ttgatagaca atgaccaagc ttaaaagatt agccacgaag gaagatgaaa ttgtagatgt
     1621 taaaattccg atttcaaacg aagaattaaa agatagggct aaacaatatg atttattaac
     1681 tccaaaacga tttgcaacaa ggtataacaa aatgttgttc ttgccaacgt cttttaaatg
     1741 gaacggttct gaatatccca ttcaatataa ttactgcatc aatccgtttt gttgtaattt
     1801 tgggaaagaa cagcacaaat tcaaagatgt aaaagggaaa ccaagtcgat ataaaatgac
     1861 tggtagttcc aaagataaag gtcataaagg tatgtactgc aatgacaatc ctattggcag
     1921 aggtgtatcg caaaactgta cagtaacccc tttatctaat tggtctgttg ttgaagaaat
     1981 taaacgcctt atagaaatca atagcatcca agatgttgag ccagattatc aatttcataa
     2041 agaaggctgc tcggaagaag aatcaacccc attcaatgag ccgaagcaat tttacaaaag
     2101 ggggaaaagt aggggcaaat ctcaacgcta tcaatgtaag gcgtgtaaga agttcactaa
     2161 tgttctacca aaaagagaag aaaccactac ttatcaccaa caaaagaaca ccattcttcc
     2221 aatgttcgct aagatggttg ttggaagggt ttcagtcagt cgtacttgtg atattttagg
     2281 aattggagtt ggaacctact atcataagct ggagtggctg tataggcgtt gtttggagtt
     2341 tttagaacga tatgagacac aaccccttca aacaaagaaa tttaacgaga tgtggcttaa
     2401 tacggacaag atgcactact acctaaataa cgtccgtaag aaaggacaag gttcaaagaa
     2461 atatacgggg tttgaagacc ttaatatgca aacgtatata gttgtatctg ctgaggtctt
     2521 atcaagatat gtgttccgtt ctgatgttgc ctatgattgg aatatttcaa tggatgaatt
     2581 aaatgaagat acaagaaaat tcaaagaaga ccatctcaat acttttagtc gtaaaaatga
     2641 taggttagat tggtcttatt atccacaaga accatccgct aacgatagcg aaaataggaa
     2701 tgcttatctt cacgaattag ggaaaattac taataggagt agatttgtcg atggtttaaa
     2761 tgttgatgct ccttatacta caactgctca ctattggtta attaaacaaa tggttaatgc
     2821 cgacgaatgg cgaatgatta gtgatgatga cttctctatt agaaacgcct tttatagagt
     2881 attcacgaaa gaattaaggt tgagcgatgc acatcatttt atttgccaag ttaacaagac
     2941 gaaaagcaga aaacaatgct taaaagaatt cggacaagca aaagcagaac tgctcgattg
     3001 gggagatatc agaggattca aaacaaagtt tctacggact ttggcatctc attatctaac
     3061 tgaattacta acaagtcatc aattccacga agaggctatt agtaaagatg gagaaagata
     3121 tcgcaaatat gccgataacc ctatcaaaca tccattagcc actaaggata aaggatttta
     3181 ttcagttgat tgtagaacgg atttatctgc tctggaacca aacgaaatcg caaagatgct
     3241 attaaatgtt aatgaccatt cgaccaatag ctttattcaa cagataagac gttatatatc
     3301 atctcttgaa agaccattaa caacagctcg tggtgataag aagagctata tttacgctaa
     3361 cttcaatccg aagtatgctc aatttgcgat tacaattcta agaacttact acaacttttg
     3421 tcgccctttt aaatcagcgg ataaaaaggt tttgacacct gctcaaagat tagggattac
     3481 agataaacaa tttgattgga aagatataat ttatttcaaa tgacaaaaag agcttggagt
     3541 aatcccaagc tcttgtgctt tatctttact gttcttcttc aattaacgca cccgttaact
     3601 caataagttt tttctttcat atacatgaaa atagtagtta tacggatttt tatcattctt
     3661 tatccctttt tgggcaaata cctcattcca ttcctcataa ttcacttctg gaaaaaaagt
     3721 atctccttcg aattcatgat gtatttttgt gatgtacatt ttctcaacat aagggaaaaa
     3781 caaattataa atctgttctc ctccgaaaat aaaaatttct tcttcgtttt tacataactc
     3841 aaaaacatct tctattgaat gaacaatttc acaaccatta aaggtaaacc ccttatctct
     3901 cgtcagaata atatttcttc tgtcaggtaa ggctcttccg attgattcaa ggttcttcct
     3961 acctaatatt atcggatgtc cctttgtagt atttttaaca tattcccagt ccttgggaat
     4021 cctccaagga atgtcattct ctttgccaat cactctattc ttatccatcg cagcaatcaa
     4081 agaaactttc atttataaca cagccttttt aactaattta ccatctaatt tcttatttct
     4141 atcaaaaaac cttttctcat tatcctgccc gttagttgaa taagcaattt tttctataag
     4201 ttatattatc ataataccac aaaatcacaa attttcattc aattatcatt ttcaattgca
     4261 ttttataaat cattttgtat gtaatttggt atgtaagtta aaatgaaaaa agtagtccat
     4321 tttgaagtac attttgtcat tttgtactcc aaaactgaac tacttagtat agattactgt
     4381 tgcttcttta ctaatttagg tttacttgtt aagaaagatt atttacgcaa atgttcttca
     4441 acaatttgct gagatttatc agctgtatct tccacttcat cttttgcttt ttctaacttt
     4501 tgaatatatt gtttccagct tgagttttca gcagttgctt cgtctaattt cttttgtgta
     4561 tctgttaact gagtttctac atttgttttt tcttgtgtca gtgttgcgat ttgttgattc
     4621 aaaccattta cagtattttg taattctgaa agttttgctt gtgcttcttg tagtcttgct
     4681 gtccaatctg cattcagatg attgatttca tcattttttt ggttgatctc atctagtttg
     4741 acattgattt cattttgttt gctttgtagt tgtgcatcct tgctgactaa ttgactttct
     4801 aagttttgtt tttctgctgc cgattgattt ttttggtttt ctaattcatt tacttttgtt
     4861 tggtattctt ggacatctgc ctttgaatct tgcaatgtct gttctttttg tgctagtcga
     4921 gcggtaagat ctgtaatcgc ttgctcttta tctgtcaatg tatgatcaag ctgtgtcaga
     4981 ttctcattga ttgtatcaat atctgtctct ccaccccaca aaataatttc atttgcgtac
     5041 cgcgtgcctg tgtagccaat tagacataga aatgcaacga caatcccacc agtaataaat
     5101 ttctttttca tttgcatagc tccttaatcc aatactttta catgctaaaa gtaagtgatc
     5161 tcaaa
//
LOCUS       DADVXV010000129         5008 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.133, whole genome shotgun sequence.
ACCESSION   DADVXV010000129 DADVXV010000000
VERSION     DADVXV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.133"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(57..130)
                     /locus_tag="KB969_002694"
     tRNA            complement(57..130)
                     /locus_tag="KB969_002694"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(94..96),aa:Ile,seq:cat)
     gene            complement(319..1338)
                     /locus_tag="KB969_002695"
     CDS             complement(319..1338)
                     /locus_tag="KB969_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBB6870608.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1335..1559)
                     /locus_tag="KB969_002696"
     CDS             complement(1335..1559)
                     /locus_tag="KB969_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBB6870609.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1556..1849)
                     /locus_tag="KB969_002697"
     CDS             complement(1556..1849)
                     /locus_tag="KB969_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870610.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(1886..2023)
                     /locus_tag="KB969_002698"
     CDS             complement(1886..2023)
                     /locus_tag="KB969_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBB6870611.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(2025..2456)
                     /locus_tag="KB969_002699"
     CDS             complement(2025..2456)
                     /locus_tag="KB969_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870612.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(2470..2964)
                     /locus_tag="KB969_002700"
     CDS             complement(2470..2964)
                     /locus_tag="KB969_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870613.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(2964..3413)
                     /locus_tag="KB969_002701"
     CDS             complement(2964..3413)
                     /locus_tag="KB969_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870614.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            complement(3417..4037)
                     /locus_tag="KB969_002702"
     CDS             complement(3417..4037)
                     /locus_tag="KB969_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870615.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            complement(4037..4945)
                     /locus_tag="KB969_002703"
     CDS             complement(4037..4945)
                     /locus_tag="KB969_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBB6870616.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
BASE COUNT         1370 a         1084 c          794 g         1760 t
ORIGIN      
        1 ttgtataata ctcttcaaaa aattctaaca cagaacgatt caaatggcta cgttaatgta
       61 ccctgtagga ctcgaaccta cgaccggacg gttatgagcc gtctgctctg accaactgag
      121 ctaagggtac tggttgttgc cacataaagc cataaacaat caaccagtag aatgtgtggc
      181 aacaaacctg ttatcgcata gcttggagtg tgactattat gggtgatagt gaagatatgc
      241 gataacatca ctattttatc gaatgatttt tatagttgtc aatatagtta tgtaatgctc
      301 ctcaacgagg agctattttt atcgtttagg aatatttaaa taccaacgtt tgtcatggaa
      361 atcttgcgca ccgcctttag tgtttccctc tggatcattc gttgcccgca tcatgacata
      421 gactttctta ttagggaagt tacgcatgtt aaaagataca tgatagccaa catttccaga
      481 agtattataa gcttgattta catctgctct ataaattcca tcagctctta ctcgagctaa
      541 ttctttccca gtattgtaat ccataatgaa gatatactcg tatttatagt tagcaatgtg
      601 ccatccagct acatgcaaat ttgcattttc gatttctcca aactgatcaa tgtgggcgta
      661 attcgttcca tctgtcagtg taggattagc tgcaccagct cgtgttggat caatgacagg
      721 cttgttttca gaagttgttg gattttcatc ggtaaatcca tgagctaaat catatgctaa
      781 tttttcttta cttacgccca tttcagaaag ataaccgtaa ggatctgtat gatcgcccca
      841 gatgttttgt gttacccata aatgcgattt gattcccggt tggttataag gagtgtccaa
      901 cgttaatgga ataccatatt tcattgctga atctctagcc aattcaacgt atgccttgta
      961 gtttttctca aacgttgctt tatcatgtgt gtgttgtaac tcaatctgca caggactgtt
     1021 ggcattagca tacgaaccag caccgtactg tacataacca ggttgaccga cttgataaac
     1081 aattccgccg tctcccacaa tataagcagt ataagcgcta gtccatgaac gttgcatata
     1141 ctgcgcttca ttgcgtcctg ttgctgtttc attagccgtt tcatgcagta aaatatactg
     1201 attatttgct acttgtgagc taccttcatt tgcgcccaaa ttaaattcat tgttgatagt
     1261 ataggcaaat ccgttaattg gcaataaaaa aagagccgtt aacaggctca tcgcagtaat
     1321 agtaattttc tttttcattt gtttcctcct tcttcgcttt cagccgagaa cattttgtag
     1381 gttcgatttg atacacccaa cacactccct aaaaacgcgc caaaaccagt aatgatgaca
     1441 acacagatat ctgtgtactg ccaattgagc gctttaccaa ctaaccccac gaaagtagct
     1501 agtgcgggaa taattaccag tgcgaaccat tttagtactt cgaacgtttt attattcatt
     1561 ttcttctctc cctaaacaaa gttttgattt gttgcgtgtg ttccaccaat ttttctgtat
     1621 gtgtatctaa tctttcatcg tgtttcttta gttcttcatg aatcatcaat cgatctgatt
     1681 tgctcgattc taaatcttta gtcagcaaat ctaaattgtg gcttactttt gaaagagtct
     1741 cagtaatttt cgagaaagat gcagcaatcg gtctaattac taataaaatc aaagaaacga
     1801 tagcggttat tgatcctgct atcattcccc attcccctaa attaatcatg tgacaactcc
     1861 tttaccttaa ataaaaacgc atcaattaag atgcgctctt atctttatta atgattttat
     1921 ctgcttcttc gtctgtaatg cataatggaa cgaaaaccat tacttgttcg ttagtgaaac
     1981 agccccagtc atacattagt ttgatatctt catatgaata catgttactt cccaccttgt
     2041 aattgttttt tgatttcttc gatttccttg gtattttgta cagaagcaag catcgttttt
     2101 gaattcaact gcgctaaact ttctgacttt tctttcaata agacattttc ttgcttgatt
     2161 gctacattgt ttagcattgc tttagaattt agctgtttca attcatcatt ttctgccttc
     2221 agcgtttcgt ataatgcctt aatattagcc aattcatcta cgctatcaac agcattccct
     2281 tttttctctt cttcagtagc taactcaacc cactgttttt tatcaaaatc aaatcttggt
     2341 ctccagttag gaactggtgg tttaatctct gtacagtttt cagggatatt ttcttgattg
     2401 ttcaaaatga tttgctcgaa tccgtaaggc ttgattgatt tgtaaactac tttcattaga
     2461 tttcctccct taaattgaat aagtgataac aaatgaataa gctgatccat aacttgaatt
     2521 tcttctccat ttaatggctc cgtctgcgcc aatagatagt tgagcactgt tcaaagtaga
     2581 acggtctatt gacccaacca gttgttcaaa actaattggt gtccgatagc cttctggaac
     2641 agttaaaata accgaatcat tcccgccact actttttccg tttaaagcca caaaatatat
     2701 agaaactgtt tttccttcac gataaagctt tgctgtccct gtattaccgt tagtgacaac
     2761 cagatttacc acttcatatc tgttatcatc agtcgtcaaa acacgtttat tattgattgt
     2821 tacagaacct gaaaaattct tatgtcctgc aatggcttgg tctccatctg tctgcaccaa
     2881 tgcttcttta ccatcaatag cttctacatg cgtttttaag tatttagcaa ctccgtcttc
     2941 ttttaattga acaatatcag ccattaaacc gtccccactt tctcaaatgt aatattcgct
     3001 aatccatcaa gtttcacttt atcggttgct gacattaaac ctgctgtcgt agttgtagca
     3061 ttacctggat ttttctgtgc tccagctgca attccatcca acttagtttt atctgtggac
     3121 gacatcaacc catttgctgt agttgtagct acagctgtag ttgtggcatt tattccagga
     3181 tcacctttat ctccctttgg taaaacaaaa ttaaatctag ctgcagatga tgttcctaca
     3241 ttcgtaacag aagcggttga accactagaa acggttccta tggtaattgt tgctgcttgg
     3301 ccaggatcgc ctttatctcc cttcaccgtt gttggtttgc cttctatagc attccaatga
     3361 gtttgtggat aaacctgtac attgctttgt tttattttta cgatatctgt cattctctat
     3421 acctccccaa ttttttcaaa agtaaaattt ggaattcttt cgtttgtgta attttctgct
     3481 tgatttacag cttcttggaa tttttgatct acatatgact gattgacacc accagtccca
     3541 ctaccacctg tagaactaat tgttccatct tcatcaatag tgatgttttc tccagcagta
     3601 taatttttca gtgaatcgag tttttctttt aactccagcg aaaaattgac atcagattgt
     3661 ctgactgcag agactttccc tgtctcatca atcgtcaata attcaccaac ttttatgcca
     3721 cccaaacggt cgatagtggc aactggcaac acgtagtcac cttctccact gtttaaaatt
     3781 ttttgataca tttctgccgt gataatgccg tcatcttctt cacttgcata gggtaattct
     3841 gtgagaacat tctctaatcc caaatcttct ttagtaatga cgacggctcc aatttttcca
     3901 ttaacagata aaactgttgc ttctcctgct attatttctt ctaacccaag aactgcggaa
     3961 gcatgtgtga ttggaaagaa ttggcgttgt acacccgttt tttcatccgt ttccatcatt
     4021 cgtttagttt tagccattag atcaccccaa ctttctcaag agtgaacaca ttttgctttg
     4081 gatcatcaac ggttgcgatg atcaaggctc cttcttcaat cgggaatgct acagttccaa
     4141 ctttttcgac ttcatgatta tctgaaaaga gatcatcctg caaaatatca gtcacttcaa
     4201 tctccccgta ttcaatcgtg aaaagcgttg ctcgcaattt ctgatataaa tagtccatat
     4261 ctgccagcaa acgctctgaa atagacgcat gacgaactcc ttgaatatct actcgcgcat
     4321 ccgttagttc ggctaacatg actccacctg gatcaatcgt ctttaaaata tccttgattg
     4381 attcaaacca tgccaaatag tctgattctt gtccttctct ccaatcttgg aaactgtgtt
     4441 cctgttcttg tctccaacgt tcaaattctt ctttcctttc attcatccag tccgtaaaat
     4501 cgcctttatt ttcattaata aagtccgtca tatccgcaat taaatcttcg attgattgcc
     4561 aataagaacc catttctcct tctgtttttg aaacagcatt aatgacaaaa taagagaagt
     4621 cttgagttgt tccaatcaag tcttctcctt taaatataat gaaattggct gtttgtcgat
     4681 gtaaacactg catggaatat ttatcaaaaa tatagttaat tttccctttt ttagcatcca
     4741 caatttttgt ttctaattgg actggatatt tcccacctac aactgattca aaatatacct
     4801 tacattctga taaatcgtag ggaagaccat tttcaactat agtcgcttcc ataacctctg
     4861 tattcttatt gccttgtcga acttgaatca tccccacgta attatagggt tctgttgtac
     4921 ttaatatgac attccacttt gccattaaat cacctcccta ttttggtggt atgacaatgg
     4981 aagaaattgc acttgcacta taatactg
//
LOCUS       DADVXV010000130         4994 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.134, whole genome shotgun sequence.
ACCESSION   DADVXV010000130 DADVXV010000000
VERSION     DADVXV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.134"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            142..1269
                     /locus_tag="KB969_002704"
     CDS             142..1269
                     /locus_tag="KB969_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6870617.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1487..2629)
                     /locus_tag="KB969_002705"
     CDS             complement(1487..2629)
                     /locus_tag="KB969_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6870618.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2634..2819)
                     /locus_tag="KB969_002706"
     CDS             complement(2634..2819)
                     /locus_tag="KB969_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBB6870619.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3173..3418)
                     /locus_tag="KB969_002707"
     CDS             complement(3173..3418)
                     /locus_tag="KB969_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870620.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3412..3813)
                     /locus_tag="KB969_002708"
     CDS             complement(3412..3813)
                     /locus_tag="KB969_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6870621.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(4000..>4994)
                     /gene="uidA"
                     /locus_tag="KB969_002709"
     CDS             complement(4000..>4994)
                     /gene="uidA"
                     /locus_tag="KB969_002709"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBB6870622.1"
                     /translation="EFGIRSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVN
                     IKDFNLMKWIGANSFRTSHYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDN
                     VEKHNTWKEIRTENSHKTVIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVE
                     LTKELDPQKRPVTIVTYLKSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKK
                     ELDGWMERCPDTPIMFTEYGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFV
                     GEQVWNFADFATSQGILRVQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
BASE COUNT         1619 a          930 c          736 g         1709 t
ORIGIN      
        1 tcgcaacgat agcaaccgga gtttcttgat gaaaatatgc ttctatcatt acaagctcgt
       61 ttggtgtaag atgggtataa gtcatttatg ttcactctcc ttgtatgctt tagcgggtat
      121 tacaattgga gtgtaacata aatggctttt ttatttgtct cgcttaatta tacaaacggc
      181 gaagatatca atgatgatgg ctcaagaaaa aaagtggaga aagttggcgg agacacccga
      241 ccagaggccg aagctgcttt acgaaaagtt ttatcagata ttgacgaaac aggacaatac
      301 tttttaggta cggatactcg agtaaaacaa taccttgatt tttggatgga ggaatacgtt
      361 aaactaaatc taaaatacaa tacctatgaa aactaccgat ttaccatcaa aaatcatata
      421 aacggttatt taggaaagaa aaaacttacg gatctctccc ctgctctttt acaaaatttc
      481 atcaatgctg aatttaaaaa gggttactcg aagaaaacaa tgactattac tcactctgtc
      541 cttaagaatg cgctgaatat ggcggtttat ccttggggat taatcaagca aaatcctatg
      601 ctgtatgtaa aaataccaaa atatgaagca cgaccaacga ctaaaaaaga tctaaaaatc
      661 atttctcttg aggactttga tcatatgcta gaaattactc ctgaaggaca tcctttctat
      721 attcctttga atattggatt ttatacggga atgcgcgttg gcgaagtttg tggtctgacg
      781 tgggatgatg tcgatttttc aaatggaaca attactgtag agaaacaaat ggtaaagaat
      841 gacggcgcat gggtatatgg tacgccaaag acaagcagtt ccaatcgaac gatttttatt
      901 ggacaaacct tgctagcaat tctgaaaaaa cataagaaac aacaattaga aaatcgaatg
      961 aagtatggaa agctctacat tgattcaaat gcagtatgta cgaaggaaga cggtgagcta
     1021 gttacgccaa gtgtagtgaa atggaatact aggaggatat cgaatgcact ctccctctct
     1081 tttaacttcc attctctcag acatactcat gctacacttc ttctcgaaaa tggcgcaaaa
     1141 atgaaagaaa tctctgaacg attgggccac agcagaattt caattacgat ggatacttac
     1201 tcgcatgtaa cagataagat gagaaatgaa acggtcgata tcatggaaaa tcttagaaag
     1261 aattcttgat ttttgccacc gaaaaaaacc accggtggca aaccggtggc aaatccatgt
     1321 aaacatggtt tattttttac actgttttca aacaaaccct tgctatttct tcggttcgtc
     1381 ctcgtccatt ttcgataccg acagctagct tataacccaa ggtatatcaa cataaaaaaa
     1441 taaaaatagg ctatgacagc agcgtgacag caaaaaagat ggaaagttaa atatcaaacc
     1501 tcgtaatttc atttgcgagt gcttgatttg tttctggata taagtgtcca tatttgtcca
     1561 aagtagtttt aatagaggca tgacctagac gcttagatat tgcatagata tttttattat
     1621 gttcaattaa aaaggcaaca tgcgagtgtc ttaatccatg catatgaatt ggttttactc
     1681 ctgcaatttc agctagtttt tttattctgc ttaaaatagt tcttggagat ggcggtaatc
     1741 catcaaaaga aaaaaccaat tctatatttt tcccaattga ttgttgagtt tttttccatg
     1801 tttttaaatc ttcaacggtt tgtctgtcta acgaaattat ccgaatactt gatgtatttt
     1861 ttgtttcagc aaattcataa tcttgtcttg tacggatgta aattgactta tttacgctac
     1921 atctgccatt tattaagtca aagtctttcc attgtaacgc taagagctcc tcactcctta
     1981 cacctgtaac aaaaataaaa cgcatcaaac gtttataaaa ttcttcataa aaatccccgt
     2041 gataaacact attatatact ttcttaaatt catcaactgt ccaaaattct acttgaggac
     2101 gctgagtttt tattttacct atagtatcta caggattttc ttcaataatt tcaagtacaa
     2161 ttgccctttt aaaaactact ctcaacttat tgaatatctg tttaatataa tttggtgata
     2221 atggttgctc aatgcccttt tttacaacat ggattttcga taaaaactgt tgaaattcct
     2281 gtatatgaat tggtcgaatc tttacaacct gcatttctcc aaaaaaatcc aatgcacgtt
     2341 gtaaaatatg atctgttttc atatatgttt tttctacagt tcccaactta taccaaggaa
     2401 aaaaatactc tcgataaaaa tcatgaaacg ttattccttg cagataaatt ccttgtgaat
     2461 cagaaaaact ttgttttaac tcttcgagtc cccttctagc ttctccttga gttttgaagc
     2521 ctcttctggt cacttgaatt ctttttccaa agcgatcttg tcctaaagtt gcagaaaaaa
     2581 accaagtgcc tctttttctg tctttataaa cattcgcaat tttcctcatt ttactattcc
     2641 tcccaagaaa tatggagaac ttcttctaaa attgaaatag gaattctttt tatttttgaa
     2701 ttacgataaa aaaagtatcc tttctcaact aaaagttctt tacattcctt gaagatttta
     2761 ttagcatagt actgagaaaa acctagatta atcaaatctt ttcgagtagc tgttttcatt
     2821 atagcacctt ccttactttt tttcatttat ttctatcagc tgcttttgtc aaaagcacat
     2881 aggaatttca cctctcccca agtttacggc gagccttacg gaagtatcat tatcccaact
     2941 ttaaatcatc gctttttatt gactataaaa attattttag aatatttatc gctccttctt
     3001 tacagcaaga aatcatggcg caactaaaat atgctcctta aagtgttaac gtactgatag
     3061 aatctattta attttcaatg aacaataggt tttctaccta aaagaatcta ctaattcctt
     3121 aactattaga agattctttt aaacagaaaa agtggaaagg ggattttttt aattagttaa
     3181 ttttaaattt taagatcgct tctattaatt taatttctag ctgacttatc atatattcat
     3241 ctacataggt aacgaattga cctacctcgt taaatccatt tgtcaaacat aacttagcca
     3301 tataagaatg ataatgtttg agtatcatct tgatcgaaat tggatctcct tctagagcag
     3361 ataagataat ggatagtgga actaataggt actgccgctt tttagattta tctaccatag
     3421 gtcatacccc attttcaatt gttcaactgc cttctttcgt tgataccaga taccacttgt
     3481 gctcatattg agaattttac cgatttcagc atcattaaaa cctgcaaaat aataaagtag
     3541 gataatcttt cttcttatct ccgataactg atcaattgct gctgataact tttgatctga
     3601 aattaatatt tccattccaa ataagaaata gacatcttgt tcatcaaaat gagtttggga
     3661 atacctgcct tcatttgaat ctgccaatgg ttcctcatta tcctttatgt tagcgtttcg
     3721 ttttcgaata gacttagctt cgtttcgtaa tactttttta cagtaggcat caaattggtg
     3781 ttgtatagat atgtcattgt aatgttgttg catgataata tgctcctttt tccccctttc
     3841 cactaataca acaatcagaa agcccctttt tttcgaaaaa actagaaaaa aaacataaaa
     3901 atatttatca ttctttaaac agaaaatctt tctataaaaa acaaaaaaaa acgattaggc
     3961 taggctaatc gttttttgaa cattcttaaa aaatccaaat tattttttat aactgaaatt
     4021 gggtattgat gaccatcgtt tctgtagata gtaagcaatc attttaggtt ttctatctct
     4081 agtaaagatt cctttcttat ttccttgcac tcttaaaatc ccttgacttg ttgcaaaatc
     4141 tgcaaaattc cacacttgtt caccaacaaa attttcacat gtatctatta cttcgtgatt
     4201 tgcttcgtaa taagccactt gatactcttc tgtaaacatt gttggtactg tatcatgaaa
     4261 tccagctact gtatctgctc catattctgt aaacattatt ggcgtatcag gacatctttc
     4321 catccatcca tctagctctt ttttcaacag atattttgca tgtgccagat cccctcccga
     4381 aacataccaa ccataataac gatttaaaca taaaacatcg acaatatctc ctaccttaca
     4441 aacatctggc gttgatttta gataagtaac gattgttaca ggtcttttct gcggatcaag
     4501 ttctttagtt aattcaacta aaggttcaaa atattcttta gcaccttcgg aatccgaatc
     4561 tggttcattt gcaatagacc acattacaac acttgggtgg ttcttgtcgc gttctatcaa
     4621 ttccttgatc accgttttat gagaattttc tgttcgtatc tctttccacg tattatgttt
     4681 ttccacatta tcatctaata aagtggccat gaaatttaaa tgtaacccta ctgcaggtac
     4741 ttcatcaata actacaatac cttctcgatc tgctaatcgc ataatttctt ctgagtaagg
     4801 ataatgtgat gttctaaaag aattagcacc tatccatttc attaaattaa aatctttaat
     4861 atttacagcc tcattcaaac cacgtccatt aacatacgaa tcctcatgct taccaaatcc
     4921 tttaaaataa aaaggtttat tattaatcaa aaatttgcca ttggtaacct gaacactgcg
     4981 aataccaaat tctt
//
LOCUS       DADVXV010000131         4979 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.135, whole genome shotgun sequence.
ACCESSION   DADVXV010000131 DADVXV010000000
VERSION     DADVXV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.135"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(82..1890)
                     /gene="pepF"
                     /locus_tag="KB969_002710"
     CDS             complement(82..1890)
                     /gene="pepF"
                     /locus_tag="KB969_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBB6870623.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2066..3064)
                     /locus_tag="KB969_002711"
     CDS             complement(2066..3064)
                     /locus_tag="KB969_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBB6870624.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3290..3943)
                     /locus_tag="KB969_002712"
     CDS             complement(3290..3943)
                     /locus_tag="KB969_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBB6870625.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="KB969_002713"
     CDS             complement(4275..4673)
                     /gene="spxA"
                     /locus_tag="KB969_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBB6870626.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1480 a         1031 c          761 g         1707 t
ORIGIN      
        1 taaaaaaata cgtcgactcc cttacaagag agccgacgta tttttttcgt ttctattcga
       61 gaaaatcaaa aatagaaagc cttataaacg atcgatcaat tcttctaatt catttagacg
      121 ttgttcaaac atcgacattg catcttcaat atatgcagcc tgtgtcatat caactcctgc
      181 ttttttcatt acttccacag gataatcgct gttacctgct tttaggtaag ccaagtagtt
      241 ctctagtgcc tctggttcct ggtttagtat tttcttcgcc agtgctgaag cagcagaaaa
      301 gccagtcgag tattggaaaa catagtaatt ataataaaaa tgcggtatcc gtgaccattc
      361 gaatttaatt tctgggtctt cttcgactgc tggaccataa tattttgcat tcaatttacc
      421 ataactatca cttaggtatt cactagtcaa tggcacacct ttttcatctt ccgtatgcat
      481 gaaatgctcg aattcagcga attgtgtctg gcggaaaact gttcctttaa acccatccaa
      541 gtaatggttg agtacataag cccgtacacg agggtctttt tctgtttcca ataaatactc
      601 cgttaggata ttttcattcg ttgtcgaagc aatttctgct aaaaagatgg agtagtcgcc
      661 gtacacataa ggctggttcg aacgagtgaa ataactatga acactatgtc ccatttcgtg
      721 gacaagcgta aatagctgat ccagcgtatc atgccaattc aataaaatat atggatttgt
      781 gtcatagctt cccgaagaat aagcaccgct tcgtttccct ttattttcga caacatcgat
      841 ccaacgttca gagaatgctt tttctacgat ggccatgtat tcttcaccca ttggtttcag
      901 tgcttctaaa gctttttctt ttgcttcttc gtacgtaaag gtaattggag cttcccctaa
      961 gaccggtgta taaagatcat acatgtgcag tttttccact tctaataaac gtttccgtaa
     1021 ttccatgtat cgatgtaaca aaggcaaatg cttgtttacc acgtctacca aagtatcgta
     1081 tacactttca ggaatatgat tattgctcaa agacgcttct ctggcagagc tgtaattacg
     1141 gactttcgct ttaaaattat gtccttttat atgtgtgcct aaagtagaag caaatgtatt
     1201 tctaaattgt tcgtaaacac tgtacaaccc cttaaatgct gcttcgcgca cccttcgatc
     1261 cgtgctttct agcaactgac catacacgcc atgagataat tggactattt caccattttc
     1321 tccttcaatc gttggaaaaa ctagatctgc attattcaaa acagcaaatg tatcacttga
     1381 agcatcaaag atttcacctg ctccagcaag aagagattcc tgctcagcag ataagacatg
     1441 ggctcgatta tctactattt gctggatata atggcgatag acttccaatt ttggttcttc
     1501 tttgaaatat tgccaaatct ggtcatctga caattgcaat atttctggtt caaaccagga
     1561 aacggcttca ctaactttcg aaaacagact gcttgctctt gcataaagcg cttggtaatc
     1621 tgtatttcca gtgtcttgat cgtttttaag gtgcgcatat acataaatga cttcagtttg
     1681 gcgataaacc ctcaatacga attcaatcgc atttaaaaat tgagaagcgc cttgatcaag
     1741 tgttcctttg tgtttttcag attgttttaa ctcttctgat aattccaaat atttctcatc
     1801 aaactcttgg tcgcttgaaa agatcttggt caagtcccaa gttaaatttt caggcaattc
     1861 ttctcgtttt ggcaactgct ttacttccat gaaatccact ccttttcttc ccttagctct
     1921 atctatcaaa atagatcata gtctaacatc cacatgtcac agcatctaac ttttctactc
     1981 attcatgtgt ctgcttccat caattttagc ataactaaat cttgttttac atagaaaacc
     2041 gattcctagc ctatttttat acttactatt ttttcaaaga agacaagtgt atgcattcgt
     2101 taaaaaactg ctgatagacc atctcttcat caatcatagg aaaaagccat tcccttttat
     2161 gttcttttat ttggcaaagc catgagttga aatcaggaac tttctggttt tccaaggctt
     2221 cttcgtacaa cattcgataa agaaaaacct gttcttgtaa ataaaagaaa aaccgacttt
     2281 tttgatagat ccacgatgat agatgcaaaa gatgtttatg acgcaagtag cattgttctt
     2341 gtatggatac tgtattcttt tgcttgtgaa taagttggcg tgtcagccat ttcttcccat
     2401 cttcactcac tttttctatt tttttcattt ggttcatttt aatttcgtta ctagtgaata
     2461 tttctttaag gtccctacta gaaaaagtcc agcagctact gcaaaaggaa atatgccctg
     2521 atacagtctc tgtaatatga tgatacaaat aaagcttttg tttcttgaga tcagctttcc
     2581 agcaatgcac tcctcttttt ctattatagt agcagcaact tttttctatc aatgagaatt
     2641 gcgattgtcc aagaaaagaa ttaccaagta tccaccatac ttggtaactg ttattcaaat
     2701 aattttgggt tctttcaata aatctctggt gagacagtct agaacattgg atttctattg
     2761 ctagattcgc caacaaaata tccggccttt gccgcaacct cggcaaatag gcttccaaaa
     2821 atactggttc tactgactgt cccagccaat ccatgaagca ttcctttaac tgtaagtgct
     2881 cttttgattc tctttcacta aagaccgaac agttatctga tttttgatgg gcaaaatgag
     2941 cacatttttt ctttcccttt ttcaaaatca ctctttttcg acagccacga caataatatt
     3001 tctttccttt ttctgcatgt ttagcaaaac agcacttatt atattcattc attgcaagca
     3061 gcatttttct ccctctgaac ttatttacgt ctaagaattt atttacacga aaaaagaggg
     3121 cgtgaaaaag ctattctgca tcaagtaata agaacagcta aacaaaaata gttcccaata
     3181 tttttcgttt ggttgggctt gttaccgcag atgcaagctt ttgaacacat ttatacgaaa
     3241 aaaagactgc gacacaattt ttgtcacagt ctcttactat aatgctgatt tatacaaaat
     3301 aaaatttcgt tcgctcgata gcattacgcg ccatcagaca ttgtccatat tcattcaatg
     3361 tttctggtgt acgatcgctc ttttcagcaa actccaaaat tcgagcaatc tgattctcta
     3421 catccgcttg gttgagattt tccatccaga agtgaacgac taggtaatag cgctcttcga
     3481 ataaatacaa atcagtccaa gcagactcta gttcgacatc tgttgcaagt tggatcactt
     3541 gttcaaaatc ttcaaaagca aaagttgctt gtctttcctg ttcttctagg gcgcttccag
     3601 ataattcttc ctccggatcg ctgccaataa tctgctgacg aagaaagtca ctcacatctt
     3661 ctgaatcaac agtagaatct tctgattgag aaatttcttc atccggaaga tttttactga
     3721 taaacagttc taatccgtct ccttttggca aaacttggaa agtgacagct tcgcttcctc
     3781 ggaactcctc ttcgatatca acttcttcca aaatactata aaagaaattt tcgatttctt
     3841 tgtgattgcc aagtaaatcc aaaaatgaaa cgccccgttc ctctaaatct tcatgaccaa
     3901 ttagtacacg gatcgtattt tcattaatat gttccatttc cattttgcta cacctcactt
     3961 tgccacaatg tttaatatag attcattgta gcgaaatcag cttaaatgta aagaaaaaaa
     4021 atctcgctgt taagcgaatt taataaaacc agcggatttt tcaacctttc aagctatctt
     4081 atttaactat aacatttttg gcagacgaat actatatagc cgacttttca gctaattttc
     4141 cctctctatt tttcgtgcaa tcatcatctt ctactacctt tttatacatc taatcaagaa
     4201 tactttttgt aaaaacaaaa aaacttggaa aaactatctt tgtaatagtc ttttccaagt
     4261 ttcgtattat ccttctataa tccagccatc aattgtgctt gacgtaattc taattgtcgt
     4321 acatcgcgcg gtaggaaccg acgaatttca tcttcattaa aaccaacttg cagacgttta
     4381 tcatcaatca tgattggacg gcgaagcaat ccaggattgt tttgcacaag ttccaataat
     4441 tcttgtaacg gcagatcatc taaatccatg ttcagttttt ggaatacttt ggaacgtgtc
     4501 gagatgattt cttctgttcc gtcttctgtc atttgtaaaa tcgcttttaa ttcagaactg
     4561 ttcaatggtt ctgaaaaaat attacgttca acaaatggaa tctgatgttc ttgcaaccac
     4621 gcacgagcct ttctgcagga agtacaactt ggggaagtat ataatgttaa caacgtgcac
     4681 cactcctttt cgtgataaga atcacttttt tgtaacagaa gatcataata atctcccatc
     4741 tgtttctatt atacataatc aacttttaaa tagctacctt tttttcataa tttttttaaa
     4801 aaaatgaaag ttatctaagg ttaatataca gtaaaaccag cattctcgct ttttttatca
     4861 tttaaaaatt agagttttca aatctaattc aaattttcta aacatatgaa acagcgtata
     4921 aaactgtact attattttat ctcaaaagct aaatgaaacc gatttcttaa gatttttta
//
LOCUS       DADVXV010000132         4933 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.136, whole genome shotgun sequence.
ACCESSION   DADVXV010000132 DADVXV010000000
VERSION     DADVXV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.136"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            85..972
                     /locus_tag="KB969_002714"
     CDS             85..972
                     /locus_tag="KB969_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBB6870627.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="KB969_002715"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="KB969_002715"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBB6870628.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="KB969_002716"
     CDS             2274..2720
                     /locus_tag="KB969_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBB6870629.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="KB969_002717"
     CDS             2993..4345
                     /locus_tag="KB969_002717"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBB6870630.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="KB969_002718"
     CDS             4516..4803
                     /locus_tag="KB969_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870631.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1395 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt ttt
//
LOCUS       DADVXV010000133         4786 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.137, whole genome shotgun sequence.
ACCESSION   DADVXV010000133 DADVXV010000000
VERSION     DADVXV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.137"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(46..420)
                     /locus_tag="KB969_002719"
     CDS             complement(46..420)
                     /locus_tag="KB969_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBB6870632.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
     gene            complement(443..1843)
                     /locus_tag="KB969_002720"
     CDS             complement(443..1843)
                     /locus_tag="KB969_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBB6870633.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            complement(1847..2257)
                     /locus_tag="KB969_002721"
     CDS             complement(1847..2257)
                     /locus_tag="KB969_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBB6870634.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            complement(2275..2766)
                     /locus_tag="KB969_002722"
     CDS             complement(2275..2766)
                     /locus_tag="KB969_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6870635.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            complement(2776..3567)
                     /locus_tag="KB969_002723"
     CDS             complement(2776..3567)
                     /locus_tag="KB969_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6870636.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            complement(3560..4333)
                     /locus_tag="KB969_002724"
     CDS             complement(3560..4333)
                     /locus_tag="KB969_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6870637.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            complement(4489..>4786)
                     /locus_tag="KB969_002725"
     CDS             complement(4489..>4786)
                     /locus_tag="KB969_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6870638.1"
                     /translation="KKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIG
                     DGITNEHLKEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
BASE COUNT         1493 a          985 c          625 g         1683 t
ORIGIN      
        1 gaagtacttt tcgttcatac caacttagag cacttcgtta tctatttatt tcttcatttg
       61 gcttatctct ataatctcat gatttggtcc gtagaaatta aagtaacgga ttccattttc
      121 ccagaacggt aattccataa tatttttatc taataattca tatcctaaat cttgaattga
      181 attgaatacc tcatctatgt catccgtatc taatgctaga tgatcaatgg ctcctctaca
      241 ctcagtagtt ttatcttccc atatttctat tatcgttcca ttcaactcga aaaagccgac
      301 tttacttccc acattcattt cttcattaat cagactaaac cctaaggatt cataaaagat
      361 ttttgaagct ccaaaatctt ttgttggaat tccaatatgt tgtaaaccat ttaatttcac
      421 ttacatcatc ccttcaattg ttttaaaatc cacattcata atttattgaa tagtctagtt
      481 tatctacctt gattgctccc tccgtaacag tcatacttaa tgctgttccg actttatcat
      541 acattctagt acttaaagca acattatcaa tatataaaac agctatcgta tcatcaacaa
      601 ttaactttag ttcatattct ttgcctattt ccaaaaatag tggtcgttgc agccccttat
      661 caaacatttg aggccaagga tagttcggag tttttccgaa agtaagctga ttattaatca
      721 atgaaatacg aaattcgtat ccttcttgag tatcactatc tacaaataat tttaaagcaa
      781 actcctttgt taacgatgta atagtcaaag ttgtttcaaa tagaaaataa tcttcgattt
      841 taggaacaat tactctttct ttttttccaa attctttctc taacttaaaa cttgaaaatg
      901 gagtgatttc tttaaaattc tcaattattt tttcaggcag tttaacacca agagttttgt
      961 ctgtcttttg aataatttga tgtggaacaa gtgcaccgcc ccaatcccag ttattttgat
     1021 cgttctcccc ttcttttgtt gccacccagc cagttagaaa acggccagtt tcattagttc
     1081 cgactgttct tgctgcataa taggcttttc cgtcgaaagc ttcgtctact ggtgatttcc
     1141 aatctgaaaa taatcctgct ccgactcgat atttagtctt tttatcttca caatactctg
     1201 aaaaaagtaa ataccacgtt ccatcaattt caaatatatc aggcatttca atcatgttaa
     1261 attcattatt agcccagtag tctcctttga aattccaatc ttttaaatct tcggattcaa
     1321 aatagaccaa tctccccgtc ggctttttct tacttgctgg ttttctagct cctagtatca
     1381 aaacgtattt tccatgatct tgatcaaaaa ttgcaaaagg atcgcgccaa tcattcttat
     1441 catatccttc ttgaggaaca agttttgctg cttcgccatc ctttttccaa tgaattaaat
     1501 ctttagaact tgcaatcatt aacacttctg aagtttttcc atccaactta gctttgcgat
     1561 tatgtccagt atacaaagct aaatactcat tgattccttg gacaatactt ccagcgtaaa
     1621 tgtattgatc aatgtcatcg ttgccaccac gatgaattac ttccccgtat tcttcaaatt
     1681 tcacaaaatc agtggttgta actagtgacc acccaaaagg atcagttaaa ggtttaggat
     1741 ttctcgtatc tcgttgatga aatagataaa aagttccatc tttataaaaa ggcatgcaat
     1801 ccccaaacca aaaatcttta ggcttgtaaa aaattttttg catttatcac tcatcctctt
     1861 cgttagtatg tctttgcata tctgcaagac acgcaattgt attcatattt cttagatttt
     1921 cgatgatatc atcgcttttt tttccttgta atctcaaatt gacagcctca atcaaaattc
     1981 ctaaattcat gccaccaaga agttgaaacc cattttgaaa tacttcactt cttttagcaa
     2041 attcgttgaa aggtgttcca ccaatcaagt cagcaaatac cataacttct tgatttttta
     2101 cttgagaaac tattttttca atgttttcac ggaattcttc aatgcctgca tctccaagtg
     2161 ttaccacatg acaatttaaa ttatcgccaa aaaacatttt taatgtatct acaaatccaa
     2221 tggcaatatt tccatgagat gtaattataa actccatcca ctcatcctct gttcttaata
     2281 aataaaatcc tttaaaaatt cttttgaatc tctaggagtt tgtatcactg tcacttcaac
     2341 tccatcacta attagttctt taaaagcctc tctctcttct tcagtaatat ttatcgtcgg
     2401 acggatgcgt tctgttccat tccttcttga taaatttcct acgtttacac ttgttattgg
     2461 taaaccgtta tcaatcaaaa atttaacatc gattggagaa actgcaacaa taagaacttt
     2521 ttgtccttca tatttaccag aaagaatatt tttaactgct acttcccttg taattattga
     2581 agttctaaca ttaggtggtg cagcgaggcg aactacagct ttttttacgt catcattggc
     2641 tacttcatta ttaataacca taattctgtt agcactcaat tgatttgtcc attgtgttgc
     2701 tacttgtcca tgaatcattc gatcatcaat acgaacatgt ataatacctt tcattttttc
     2761 atccatattc aacacctact tcaaaatatt taacgctctt aacgcaatag aaactactaa
     2821 gattaataga attacataaa ctggtttaac ctttcgtcct aacaaataat acacaattgc
     2881 tactacacat gcaggtaata aaccaggcat aacttgatca aagatttcat ttccggtcat
     2941 tgttaagtcg ccttgtttaa attcaaagcc aacattcact tttacaactg tggcaatgag
     3001 tgcaccgacc accattaacc ctaaaattga tactgcatca gtaatagact ttaattttgt
     3061 ttcaatttga gttagtaggc tcgcacccga ttctttccca gcaaggtata aaggataagc
     3121 agtaatcctt aataaaattg atgccagtat ccacaaaata attccaacaa aactaccttc
     3181 caatgccata ttagctgcaa ttgctccaaa aatagtccat ggaataacta caaatacact
     3241 atctccaatt cccgctaaag gacccattag acctgttttc agagcactta ctgcttccaa
     3301 agacttattt ttttcttctt tttcaattcc aacattcata ccaataatgt aaggcgctgt
     3361 atacggcgta gtgttaaaaa attgtaagtg agctaaaacg gattgtttca ttccttcagg
     3421 atcatcttta tatgtgtcct tgataaaagg aagcatagaa tacgcataac ccaacccttc
     3481 cattttttca taatttaatg aagttgcacc attgagaatc caccggaaaa ttacttgttt
     3541 gtcgattttt gtcagtttct tattcatctt cgtcaaaacc tcctgttgca gctggtgcta
     3601 cttgagtatt atttgatcta tttttatata cgattagtgc gattgcagcg ccaagtaacg
     3661 aaatccctaa aattggtatt tggaaataaa ctgccaaaac gaaaccaact aacaaatagg
     3721 caaagtaatc ttttgtaggt aaatatttaa gtagcattcc tatcccaaca gcaggtaata
     3781 gtccccctgc tacctttaaa ccaccggtaa cccattcagg aatataattg attgcacttc
     3841 ccactaacgt tgggcctaat atcacagtta acaaaacagg aattccagat acaaagcttg
     3901 tattaattga tgccaaatat tgcatccact ctaatttttg ataatcttct ttttgtgcga
     3961 atttttctgc cttttgttga aaaaaaatgt ttgttgacca ctttagaaca tctagttgta
     4021 caattaacat tgctaccggt attgctaaag ttattcctat agaagcatcc tggttagttg
     4081 agattgctaa ataagtaccg atcaatgctg ctgtttgata atccggtact gatgcaccac
     4141 caaaactagt aatacctagt gtcattaatt gcaaagtccc accgatataa agtccagttt
     4201 gaatatctcc cataataagt ccggtcaaga aacctgcaac gacaggttgg gaggttccga
     4261 ttttgggccc ttccttatcc cagttaatga aaaatccata caacacaact aaaaatgttt
     4321 gccaaaacgc cattttgttc tctcctttct tcttatactt ttatataagc aattactgtg
     4381 ccaactaaca ttatccaata aagcgggaaa atacagtaaa tattaattaa atgagcgtct
     4441 aaatatactt tggacaccct ttcatttttt tagacgctag tatgctattt agaaaatagt
     4501 ctgctcaaaa attgtataga ttaactcata ctctcctttg ggtatttcaa tacagtaaat
     4561 atctttgatt tctgaaaaaa aatcttttga tacatttaaa aaagtatcaa atagttgcgc
     4621 tccctctttc aaatgttcat ttgttattcc atcaccaatc ataattcgtt caatcattcc
     4681 agaaagatgt agaaatagat taattctcag aaaacttggg attttgacat cgtaatattt
     4741 ttcatacaaa tatagtactt tttctatctc attgaatact tttttg
//
LOCUS       DADVXV010000134         4759 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.138, whole genome shotgun sequence.
ACCESSION   DADVXV010000134 DADVXV010000000
VERSION     DADVXV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.138"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            175..519
                     /locus_tag="KB969_002726"
     CDS             175..519
                     /locus_tag="KB969_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBB6870639.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            520..939
                     /locus_tag="KB969_002727"
     CDS             520..939
                     /locus_tag="KB969_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBB6870640.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1031..1381)
                     /locus_tag="KB969_002728"
     CDS             complement(1031..1381)
                     /locus_tag="KB969_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870641.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1347..2678)
                     /locus_tag="KB969_002729"
     CDS             complement(1347..2678)
                     /locus_tag="KB969_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBB6870642.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2934..3500
                     /locus_tag="KB969_002730"
     CDS             2934..3500
                     /locus_tag="KB969_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBB6870643.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3645..3732
                     /locus_tag="KB969_002731"
     tRNA            3645..3732
                     /locus_tag="KB969_002731"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3677..3679,aa:Ser,seq:cga)
     gene            4066..4632
                     /locus_tag="KB969_002732"
                     /pseudo
     CDS             4066..4632
                     /locus_tag="KB969_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
BASE COUNT         1739 a          797 c          910 g         1313 t
ORIGIN      
        1 aaaataaaaa aagcgttagc aactatgctt aaaaagcata tcgactgaat aaactaagca
       61 ttggacaggc tgaaagacta catttaaaat gaaatgcgaa gaaacaatag aaaataaagt
      121 tgccttagaa ccatagttga atcacctaac agtcgtgaag ggagaataag agaaatggca
      181 gaaaaacaaa ccgcaggacg agatcaatta ggagattttg caccaaaatt tgcagaattg
      241 aatgatgatg ttttatttgg acaagtatgg tccagagaag aattatctgc tcatcagcgt
      301 agtatcatca ccatatctgc attaatttca ggaggaaatt ttgaacaatt gccagctcat
      361 ctgaagattg gcaagcaaaa tggcattact agtgaagaaa tagcagaaat cattacccat
      421 ttagcttttt atgtaggatg gccaaaagct tggtcagctt ttagtttagc aaaagaaatc
      481 tatttagaag aaaatagcga agataagaaa gaggcgtaaa tgacgacaaa acacgaagaa
      541 atacacaatg gcgtgatttt tccagcaggt gaaaaaaacg aagcttacgc tcaagtattt
      601 accgggcaaa gctatctgaa tatgttagtg aatgatcccg aagtttctgt tggtgtaggt
      661 aatgtaattt ttgaaccagg ttgtcgcaat cactggcatg tccataaaga cggctatcaa
      721 atcttacttg tgaccggagg agaaggctgg tatcaggaag aaggaaagcc agcaagacga
      781 ttaatggctg gagatgtcgt cgtaacgcac aaagggatta aacattggca tggtgcgaca
      841 aaagacagtt ggtttgaaca tttggcgatc actgctggta attcagagtt tttagaacct
      901 gtaacagatg aagtgtatga aggattggaa aatcaataat gtcaagcttg aacagctcct
      961 gaaagtagat tttaatcgaa ctttcaggag ctgctttttt gattcagtct tttataaata
     1021 gaaaataggg ttaataatag gaatgagaag cacgtcgaaa gatcttaata ttgataatcg
     1081 gctgggcata catgatttcc acgtcatcaa tcaaactacc taacagatga taatcttccc
     1141 gatcatgtcg gggattacct aatagttctt gatagtagat ttccatacta gggtcccgag
     1201 gattgttcag caaatcagca agtacatcta aatcttctgg ctgagtttct gccgtaccct
     1261 gtatctctat gaaaagccct tcctcagcaa attctactcc aatacgtatt tcagttattt
     1321 catgggaata taaataagta agaagctcat cgatgattct ttttgataat tctttttcca
     1381 agtgtctttt tttcctttct gacagcggta aagttatcta gtatcggtac aaggatacct
     1441 gcaacgaaac cagttgaaaa accactgtta tatagattta gtcctccgtg caaagtgctg
     1501 acgttatgga caagagcaat atgtagtaca ccagctatta caccgtaaaa actgccgtaa
     1561 aaaccgctta tgggcgcgag acctgtccca aacacagctg caacaagcat gccagtactg
     1621 gtgatctcat gaaaagttcc aaacaaagaa gcaataaata ttccgactag tatcggaaaa
     1681 ctgtttttta aatgacaacc aaaagcactg aaacccaccg cagataaaat agcaccgatg
     1741 acaggtccat ttaactgacc gccaaccagc aaaacataag aagacagcat cagaccaact
     1801 aagcctatgt tgatcaaagt agcaccaata ccagaattag caatgaaatc agttgtcaat
     1861 tttccagatg aatcgaaaat ttctcgaatc cccaaaagcc gaaaggaatt ataatagaaa
     1921 ccaattccga ctgtcagcga aaaaaagcca aaaataatcc aaatgagagg aaagtgatat
     1981 tcattgaaaa ccaatgtatt ttcgacgatt gaatagctga ataacctcaa aacagcagta
     2041 aaagtcatcg caatcaaccc agaggtgaat ccaatattat aaagtgtgaa tccacgatgg
     2101 aaaactaaag tttgagcagc taagggcgga agaagtagac caattgctat gccagctaaa
     2161 ttccccaata aaatacctat cagtaaagga aaacgcatac caaaagtgat ataactaacg
     2221 accggtgata atgcgctacc aaacagtccg atcatgatgt actgagaaaa aggtttattg
     2281 acaaatacag cgtatagata cacacctaaa atgattgaga tagaattata aaggtttttg
     2341 ccaaaaaaag agaaaccggt aactgttaga atcgaagcaa ataagggacc gtttaaaatc
     2401 accttgtgcc gataagctaa aagcacagaa agtaaggtca aaatccctac atttatgaat
     2461 gcgcttccga aaccgcctaa agcaaaataa tctgtcaaaa gattgcttgg cgaggtaaga
     2521 atagttagca atccactcca attatcagta ggagtattag aaagcaagcc aataaaaaga
     2581 aaaaaaacac ctgtaaaacc aagataaaaa tactttcttt tctgtgaaac gattcgtttt
     2641 tgaggatgaa tataaataac gtcagtttcg ttttccatta cacaccttct ttttcatttt
     2701 ctttaactat aacttgaaat gaaagatttg gacaactatc atttaggtca aaactaaaaa
     2761 tgtaagggaa cccattgaat ttaaccaaat ttttttaatt ttgcaaaaaa aagttaaaga
     2821 agactgaaaa aaaatttaaa atataacgtt ttgagtaaaa tgtttgcaaa aaatgctaaa
     2881 aatagggtac aataaaacaa catatactgc agtaaagaag tgggggagtt ttaatgagaa
     2941 gaaaagtcta taccaaggat caaattctaa aagctgctta tgatgttgtt gcaaaggaag
     3001 ggtttaaagg atttactgcg agaaatattg ctaaaaagat ggggatttcg acacagccga
     3061 tttatctgga attcaaaaac atggaagatt taaaaaatac gttgctggat tctatctttg
     3121 aacaactaaa agaagatgtt ttccctattg aacgtactgg tgataaaatc attgatctcg
     3181 gtttgaacta tatctacttt gcaaaaaagc atcatagtct ttacatggca ttgtacattg
     3241 atgaacatgg ggacggaaag aaaatgcatg atttttcata caattatttc cgtgaaatag
     3301 ttaaagaaga tgaaagatac aatcaattat cggatgaata tgtcgatgct ctgcatactg
     3361 gtacatgggt agcagtgact ggcttagcgt cattgatgtc atcaaacatc atgcatccaa
     3421 cagaagaaca aatcattgca ctgatcaaac ggacaattga ctcgatttta gcattagata
     3481 atcctgaaat aatcagatag tgttctatca gtatgaattt gatcggtaag tccgttggct
     3541 gcaaactgtc aatggacttt tttgctaaaa aaagcgattt ctgttattta tctattagaa
     3601 ataggcttga catttcgtga aaaaagttta aaaatagtac ttacggaagg ttggcagagt
     3661 ggtaatgcac cggactcgaa atccggcgaa ccggctaata ccggcgcgca ggttcaaatc
     3721 ctgtaccttc cttatatcaa cgattagagg ttgtgaagaa gctgtcctgc atcaagtaat
     3781 aagaacggcc aaacaaaaat agcttttcct attttttcgt ttgattgggc ttattaccgc
     3841 agatgcaagc ttttgaacac cgtttgttcg gaataagggg ctgtgacaag acttttgtca
     3901 cagcccctta ttgttgtact tttaacctac aatatttttt gattccccct gagtactatt
     3961 ttttataaat gctagtaaat caatcttctt tggccttttt ttgataaaaa aaatactaga
     4021 tgtaagataa aagtgtaaaa acgatttgtt ttaggagggg aaacgatgtg taccgcaatc
     4081 acttatgcaa cgaaagacca ttattttgga aggaattttg attatgagat gtcttataat
     4141 gaagtggtca ctattactcc aagaaattat cgtttcgatt ttagaaaggt aaaaaattta
     4201 gataaacatt atgcaatgat aggaatagca gctggggtat ccaactatcc actctattat
     4261 gaggctacaa atgaaaaagg gttgagtatg gcaggactga attttcctgg caatgctgat
     4321 tataaagaat tacaagaagg aaaagataac gttgcaccat ttgagtttat tccatggata
     4381 ctagggcaat gctcaaccat agacgaagct aaagaattat tggctactat caatctagtc
     4441 aatatcgatt ttagtgaaaa actacccttg tcacctttac actggttatt agctgataaa
     4501 gaaaaatcga tagtaattga aagtatgaaa gatggacttc atttatatga taatcctgtc
     4561 ggtgtgttga caaataatcc gccatttgat tatcaattat ttaatctgaa caattatcgc
     4621 tcgctatcaa atggaacgag agtataaaat attttgtgta aatgaaaaaa tccatacaaa
     4681 aaaggaagtc ccttctgtag aataaagtta acgacaacca attcacagaa aagaggactt
     4741 ccctatgaat gattttact
//
LOCUS       DADVXV010000135         4756 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.139, whole genome shotgun sequence.
ACCESSION   DADVXV010000135 DADVXV010000000
VERSION     DADVXV010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.139"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(207..1169)
                     /locus_tag="KB969_002733"
     CDS             complement(207..1169)
                     /locus_tag="KB969_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBB6870644.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="KB969_002734"
     CDS             complement(1171..2610)
                     /locus_tag="KB969_002734"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBB6870645.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="KB969_002735"
     CDS             2795..4741
                     /locus_tag="KB969_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBB6870646.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1510 a          817 c          787 g         1642 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaggc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgag
//
LOCUS       DADVXV010000136         4741 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.140, whole genome shotgun sequence.
ACCESSION   DADVXV010000136 DADVXV010000000
VERSION     DADVXV010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.140"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="KB969_002736"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="KB969_002736"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBB6870647.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="KB969_002737"
     CDS             complement(1297..2133)
                     /locus_tag="KB969_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870648.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="KB969_002738"
     CDS             complement(2317..3534)
                     /locus_tag="KB969_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6870649.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="KB969_002739"
     CDS             complement(3683..3862)
                     /locus_tag="KB969_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870650.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="KB969_002740"
     tRNA            3917..4000
                     /locus_tag="KB969_002740"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..>4741)
                     /locus_tag="KB969_002741"
     CDS             complement(4240..>4741)
                     /locus_tag="KB969_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870651.1"
                     /translation="ILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLF
                     TELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLI
                     MGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFI
                     ITVINR"
BASE COUNT         1431 a          995 c          765 g         1550 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 a
//
LOCUS       DADVXV010000137         4719 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.141, whole genome shotgun sequence.
ACCESSION   DADVXV010000137 DADVXV010000000
VERSION     DADVXV010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.141"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..191)
                     /locus_tag="KB969_002742"
     CDS             complement(<1..191)
                     /locus_tag="KB969_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870652.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(201..1016)
                     /locus_tag="KB969_002743"
     CDS             complement(201..1016)
                     /locus_tag="KB969_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBB6870653.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1278..1721)
                     /locus_tag="KB969_002744"
     CDS             complement(1278..1721)
                     /locus_tag="KB969_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBB6870654.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1855..2193)
                     /locus_tag="KB969_002745"
     CDS             complement(1855..2193)
                     /locus_tag="KB969_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBB6870655.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2181..2558)
                     /locus_tag="KB969_002746"
     CDS             complement(2181..2558)
                     /locus_tag="KB969_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBB6870656.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2782..3975
                     /locus_tag="KB969_002747"
     CDS             2782..3975
                     /locus_tag="KB969_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6870657.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4141..4563)
                     /locus_tag="KB969_002748"
     CDS             complement(4141..4563)
                     /locus_tag="KB969_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870658.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
BASE COUNT         1378 a          898 c          824 g         1619 t
ORIGIN      
        1 atgcaacctg gaccaataaa aagtaaagaa aaaataaagg aaaagacatt ccttccatct
       61 atcgacaaaa ggaacgcagc tgctatatac aagatattga cacaccaaaa acaaaggcta
      121 cttgccaatg attgatacaa ccaataaaag aattccatat aaacattttt gtcaaaacgc
      181 tgctctttca taatcacctc ctattccttc attcctgatg aagcgatccc ttctacaaaa
      241 tatttttgca tcgctaaaaa tataaaagca acaggaagaa cagaaacaac tgaggcagcc
      301 atgattaatg cgtactctgc atcaaatagc ccaataaaca ttttcaaccc taactggatt
      361 gttttatttt ccgtagaaga caaataaatg aatggcccca tataatcgtt ccatgtatta
      421 acgaatgtga tgatcgtcaa actggcaatc gccggttttg taagaggtaa aatgatcttg
      481 cgatagattc cccactctga taagccatcg atccgcgcac tctcacataa agaatctggg
      541 atactactgt agtattgctt caacaagaac acaccaaaag cattgaacgc ttgtaatagc
      601 accaacgacc acaacgtata tgttaaaccc acttttctca tcataatgaa ctgcgggatc
      661 atataagact gccaagggac agcaatcgtg ccgatatatg ctaaaaataa aatatcgcgc
      721 cctttaaaat ttagtttaga aaacccgtaa gcagcaaaac tagaagtaaa caactgaatc
      781 aacgtgatca caacgcttaa aaaagctgta ttcttaaaaa atgtcactaa aggaatacga
      841 gaccaaataa ccagataatt ctctaaatgc caagttttag ggatccattg aatcggaatc
      901 gtgaacactt cattatttgc tttgaatgaa gcagaaacca tccataaaaa aggaatgatc
      961 gtcaataaag ctaatacaat cagcagaatc atacccaacc attgaataaa gggcatgttt
     1021 tttgaacgaa tttttgcttt ttttctttca tttcgaacac ctccaaagtt ataatcttca
     1081 tttctttgta atgattacaa tccagaacaa cggttattat agctgattca tttccgttct
     1141 tcttatgttt gtaagcgctt atttaacaag ttatgtaaat ctctttattt tttttgattt
     1201 aaaaatgaaa aaatacaaaa gcaagactgt catacgtctc gcttttgtat tgaaatttct
     1261 tcgattagag atacttatta ctgttcaaaa gcttctttga aacggtgaat caattcattg
     1321 actacaggtg ataaaatccg attctttttc cagactagca tgcagttcgt ttcaatcatt
     1381 gggtcaagcg gaacgaatgt cactcgcttt gaaagatgac ttacagcacc ttctatgact
     1441 aaagcagcac ctacctgatt ctcaattagc gcaaatacat tgaaaatcaa attgtacgtt
     1501 cctgtgatca gcaactgctc cttttttatg cctaaccagt cagcaaacat tcgctgtatt
     1561 tctggacgct ttgagatcaa aagaggtaca ttcgcaaagt cttcttttgt tatcacgtct
     1621 ttttttgcta aaacagaatt ttctaaaatg agcaatcccc atttttcctt tcttggtaac
     1681 aaaatcgttt cgtatttctc tgtatctact ggatctagca aaatcgctaa atctaacagg
     1741 cttttttcta gtcactccgt gatatcatca cttgttccgc tgtggatatg aaattgaacg
     1801 ctgggataat cacggatcaa cttttctagt aatagtgcca atgtattcga attatcagct
     1861 tccacacagc cgatcgtaaa tcggccgctg aataattgtt tttttctgtt ctcgaattct
     1921 tgagtggttt gattcgttaa atctaaaatt tcttctgctc ggctttttta gaaaataacc
     1981 tgcttctgtc aagatcattt tgcggttttc gcgtacaaac agttctgttc ctagttcctc
     2041 ttctaactcc ttcagttgtc ggcttaaggt tggttgtgta agatgtagaa cttctgcggc
     2101 ttgagagatt gttccttctt ctgcaattgt ccaaaaatat tttagtaagc gtaactccat
     2161 agcgatgctc cttgattttt ttacttgata cattccattt tatttctaga taacacacga
     2221 tcatatttct tgatttttcc ttgtaaacgt tccaaacact cttgcatttc agcaatttct
     2281 ttcgtcaaaa gttcactttc ttcaatcaaa agcttacgcc gctcaaatac agttgcttct
     2341 ccttcgctag ataggcgaat atattcaatc aaagactcga tcgataatcc ggcatttcgc
     2401 atacagatcg taaagtcgac ccattttagg tcttcttctg tataatcacg gattccgcct
     2461 tttgtccgat taactggtgg aatcaacccg attcgttcat aatagcgcaa tgtatcggcc
     2521 gaaatgccct tttcttcact gacttgtttg atattcatct gatcactctt tctcttaatt
     2581 tcttgccact ttacttatgt attttattta ttctacaact ttaagtgtac tccaagtcaa
     2641 tactcatttc tattaaaact aagctggatt atctatatcg gttgtttgtg tattatttca
     2701 aataaaaaag tcttgttttt ttattctttt ttggatatac ttttaacaat ttagggaaat
     2761 tttaggaaaa ggggtataaa aatgacaacg tatcagcgaa aggtattatt atcgacatcg
     2821 gcgggaattg ctttagagaa tatggatatt atgtttttag ctttttcatt atcttcaatg
     2881 attacttctt ttcatattag tggtacgcaa gcgggtttca tttcaacgat cactaatttg
     2941 gggatgctca ttggaggtat tttttttggc atcatagctg ataaatatgg acgtgtgaaa
     3001 gtattttctc aaacggtcct tctgttttcg attgcttctt tattgatgta ttttgcttca
     3061 aacatctact tggtttatct ctttcgcttt atcgcaggtg taggagcggg aggagaatac
     3121 ggggcgtgta tgtccttgat ttccgaaagt ttttcaaaaa aacaaattgg acgagcttct
     3181 tcggttgctg gtattggtgc gcaggtcggt gcggctttgg ctgcgatttt agctgctgtg
     3241 atcattccaa cgtttggttg gaagatgttg tatgtcgtag gtgtactgcc ggtgttgatg
     3301 gtcttgttca ttcgtcgcgg cttgactgaa ccaaaggaat tcaaatctgt acaatctgcc
     3361 gaaaagaaaa ccaaacttag cagactgttt gaatcaaaac atcttgcttg gcaaacatgt
     3421 ggccttagta tcatggtaac tgtccaaatt gccggctatt ttgggttaat gaattggctg
     3481 ccttcaatta tgcaaaatcg attagggctt tcggtttctg ggtcttcatt gtggatggtc
     3541 agtactattt taggcatgtc tttggggatg atgacttttg gcataatcat ggataaattg
     3601 gggcctaaac tagccttttc tttgttttta atttgttcat ccttatctgt ctatctactt
     3661 gtgttagccc atagccagtg gagtttggta gcagccgctg tgatagtcgg ctactttatc
     3721 aatggcatgt atggtggata tggcgcagtg attagtagtt tgtatccaac agaaatccgc
     3781 gcgacggcga ataatttcat tatgaacctt ggacgagctg ttggtggttt ttcttctatc
     3841 gtcatcggtt tcttgatgga tcattatagt ttaactgccg taatcttgtt tttgagcggt
     3901 atttacctag tcagtctgct ggtcttgaca actcttactg gtgttacagc attaagggaa
     3961 agcttgcagc attgatagtt gagtctgtaa atgacaagaa agaggtgtgg caaaagcttg
     4021 catctgcggt aataagacca gccaaatcaa aaacatgaga cactgtttcc gtttggctgg
     4081 tcgtattact tgatgcaggg cagctttttc aactgctaat ttccttctat ctggcggcga
     4141 ctattctttg acgtccgtca tttcaaagta ctttactaat aacttagcat aacgaaaaac
     4201 tgtggataca ctcgtatatt gagcgtctgc ataatcttcc aaatttttct caggatgttg
     4261 atacatgaat tcaatcaaat gataattata tgattttctg tagaaatgaa gataaataat
     4321 gtagattggg aagttctcct gcttttccat agaaaagcgc cgattattct cattcttcaa
     4381 aatgacctta tcaggatatt tttggaacaa ttcttctaaa tctgttagat aattcaagat
     4441 agacttactt gataccttca attcgttttg tagttcttct attgaacacc aacgttctgt
     4501 ttcaagcagt aaatgaatca ttttaatttt cttttgagaa acttttgtta aaaaagtctg
     4561 catattttct cctcctgtat ctactttact atactacata caagaaaaaa aacggataca
     4621 aatatcatat tgtcacaccg tcaatagtgc ataaacctgt tattatttct ctttttttcc
     4681 taagtattct attgatatga atcatttaat cgtttatta
//
LOCUS       DADVXV010000138         4640 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.143, whole genome shotgun sequence.
ACCESSION   DADVXV010000138 DADVXV010000000
VERSION     DADVXV010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.143"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..774)
                     /locus_tag="KB969_002749"
     CDS             complement(<1..774)
                     /locus_tag="KB969_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870659.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNFHLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGEQEKQFAYSAHTSCDDNGFILSTIITPGNIHDS"
     gene            967..1956
                     /locus_tag="KB969_002750"
     CDS             967..1956
                     /locus_tag="KB969_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBB6870660.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1938..2399
                     /locus_tag="KB969_002751"
     CDS             1938..2399
                     /locus_tag="KB969_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6870661.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            2449..2913
                     /locus_tag="KB969_002752"
     CDS             2449..2913
                     /locus_tag="KB969_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6870662.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2927..3676
                     /locus_tag="KB969_002753"
     CDS             2927..3676
                     /locus_tag="KB969_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBB6870663.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            3676..4506
                     /locus_tag="KB969_002754"
     CDS             3676..4506
                     /locus_tag="KB969_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBB6870664.1"
                     /translation="MENSTEKKRLITKKDLNKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTSFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
BASE COUNT         1528 a          660 c          884 g         1568 t
ORIGIN      
        1 actgtcatga atatttccag gagtgatgat tgtgctaaga ataaatccat tgtcgtcgca
       61 tgaagtatgg gcagaataag caaattgttt ttcttgttcg cctttgacgt agtagccgct
      121 ttccggatca gctttactta tttttctttc tttcagcttc acttcctttt ctaagtccaa
      181 agtaaaaggg cgttttccag cctctattcg ttgacgattg atctcatctt ctaattcatc
      241 ctgataggct ttcgcttcat catgggtcat ttctttcgta aacttatgtt tattggcgtt
      301 agctttgatg tgggtagaat ctagatgaaa attatcctct gttacaaaac ctgctttaac
      361 tgcttgttct aaaatatagg caaaaatatc ctcaaacacc gtcgtttctc taaatcggcg
      421 aacataattc tttccaaaag ttgagaaatg ggggattttc tcttcgaagg agtagcctaa
      481 aaaccagcgg taagcgacat tggtatcgac ttccttaatg gtttgtcgca tggaacggat
      541 accgaataaa tactgaataa acaccaattt gatcagaatc actgggtcga tacttgggcg
      601 acctaaatcg gagtaagtgg cttcgacgat tggataaata aattcaaaat caagcgcggc
      661 atcaatcttt cgaacgagat gatcttgagg aactagatca tcaatcgtaa gcatcgcaaa
      721 ttgatttcta ccattcgtat tgtttttaga catcatagct atcactcctt gcattcgttt
      781 tcataaatct attataaaag aaaagactgt agacatcatc cataaaatgg actttgtcta
      841 cagtctggca ttttattata taaaattgtt ataaaaaaat ttttttgaaa aatagtattg
      901 caaaataaag caatttcata gataataggt attgtaaagt tatatgactt tataatactt
      961 attagagtga gggataaaga aatgagacaa ctacacaaag aacagattga aacagcaatg
     1021 gcagcgttaa aggaaaagac aattgatcat gtatatttta cagcatgtgg gggttcacaa
     1081 gccgttttaa tggctggtca atatctattt gataaagaat taactgtacc ttgtcatgtt
     1141 tatactgcta acgaatttaa ctatgctata ccaaaaggat tatctgaaaa ttctttagtt
     1201 atcacttgtt cccattctgg cacaacacca gaaactgtag aagcaacaaa aaaagcaaga
     1261 gaatttggag caatgactat ttgtttatct aatgaagaag gatctcctct atgggaagca
     1321 gctgaatatc ctgttcacta tgattggggt aaagatgttg atgctagtga tttaaataaa
     1381 ggaattcttt atggtttatt atttaatatt ttacttgttt tagatggctc taaaaaatgg
     1441 gaaacttgct tgaatgaatt tgataagtta aatgatcttg ttattgctga aaagagcaaa
     1501 tttgaaataa ctgctaaaga atggggtaaa aaccaaaaac gagataaaat tatttacaca
     1561 attggtagcg gtatcaatta cggagaaatt tactccacag cagcttgctg gttcatggaa
     1621 atgcaatgga ttaattctaa tgctattcat tctggggaat ttttccatgg tccttttgaa
     1681 atcactgatt atgatgtacc attcatctta gtgaaaagta ttggagatac aagattttta
     1741 gatcaacggg tagaagactt cactaaaaaa ttcagtaata aattaatggt tttagaccaa
     1801 gctgattttg acttagaatc tatagatagt gtagcgaaag aatatattgc agctgtactt
     1861 agtggcgttg ttattcgcca aatggtagaa gcgattgctt ttgaaagagg ccattcctta
     1921 gatgttagac gctatatgtg gcaaatgaaa tattaattaa taggaggttg caaaagatgg
     1981 caaatcaatt atttcacatt gtgattacaa cacattctac cctttgtgag ggttatttaa
     2041 aggcaacaaa attaatttta atgaatgacg ccacaggtat tagtgctgtt ccatttaaag
     2101 aaaatactag tccagatgat tttgaggaga gtatgaaaga aataattagt cagcatcatt
     2161 tgcaacctct aattatttta acggatttaa ttggaggaac acctaataat gtttctatta
     2221 aacagttgaa caacaataga attcaaatta ttgctgggat taatttacct cttttactgg
     2281 agttattaat ggcccagtca gctggtaaat ctatagaaga aatagatttt aaggaattac
     2341 tgaataactc tcaaaaaagt atggttcata ttaattcgct tttaaaagat gtcagttaag
     2401 gtggcaattt ctattctata aattttaaaa attgaaggag gaaatagaat gattaaatta
     2461 gtgcgtgtag accacagatt acttcatgga caagtaatat tttcttggac taaacagtat
     2521 gatattaacc atattattgt ggctgataac aaagttccag gagatccaat gtctgtgatg
     2581 gctttgacaa ttgctaaacc tgctgattgc aaattagaca ttgttaaaat tagtgatgtt
     2641 aaagggatta tggaaacatc cccaaatgat aattacatga ttttaattaa aggacctaag
     2701 gaagcttttg aattagttca aaatttacca gaaattaaag aaattaattt tggcggtgtg
     2761 tctaagaaaa gcgagtccaa acaatatgga aaggcagtct ttttaactcc tgaagaatta
     2821 gaagccacaa aaaaaattct tgatcaagaa gtgaaaatat ttgtgcaaca agtcccatct
     2881 tcaagtattg aaaatgtaga ttttagtaag taagggggga aaataaatgt tattaaaagc
     2941 cattttatta ggtttagttg gtgtggtagc tgttattgac tccaggttaa ttggtcgaca
     3001 aaatattggt agaccactaa ttttgagtac acttgccgga cttgtgctag gtgacttgca
     3061 tacagggatt gttcttgggg catctttaga attaatttct atgggattcg tctcaattgg
     3121 ggcggctgga cctcctaata tgcaacttgg tagtattatt gccactgctt ttgcaatttt
     3181 aactaatagt agtacagaaa cagccttaac aatagctatc ccagtggctg tagctggtga
     3241 atttatgagt attatcatgc gcatgataat tgctcaattt ggacatgctg cagataaagc
     3301 cattgaaaat aataaattta gaaaagctca aattattcat atttattggt catttatttt
     3361 taatgctttt gtttacttta ttccaatctt tttaacagta tattttggtg ctgacgttgt
     3421 ggcagattta gtagataaaa ttccagaaat gattacagac gccttgactg tctctggaaa
     3481 tatgctttcc gcattagggt ttgcaatgct attaagcaca atgttgagta aaaaattata
     3541 tccttacttt atttttggat tctttattgt tgcctattca ggtctttcac taattggcgt
     3601 gacaattttt gcagctctga ttgcctttgt aatggatcaa gttaaatatg gaaaaagaga
     3661 agaggcgcat ggttaatgga aaatagtaca gaaaaaaaac gtttaatcac aaaaaaagat
     3721 cttaataaga tgtgtcttcg ttcatggaca atcatgtgtt cgtggaatta tgaaagacaa
     3781 atgcatatgg gatttatgta tgggatggcg ccaattttaa ataaagttta taaaaatgat
     3841 gaagagaaaa aaagagaagc ttatactcgt catatggcat tttttaactg tacgcctcaa
     3901 atgacttcat ttattatggg actttgtgct tctatggaag aacaaaatgc tcaagcagaa
     3961 gaaggaaact ttaatactga atctatctcc atgattaaaa ccagtttaat gggtcctttt
     4021 gctggaattg gtgattcatt tttccaaggt actttaagaa ttattacatt tgggattgga
     4081 ttgtcttttg ctaagcaagg tagtatttta ggaccgattt tagctgttgg cctttttgct
     4141 ataccttcta ttttagctgt tttttacggc ggtaaattag gatatgagtc tggcaataaa
     4201 taccttacta aattgtatca agaaggtctt atggatcgag taatgcaatt tgcttctatc
     4261 attggtttgg ctgtagtagg tggaatggtg gctagcatgg tgccaattgt caccccttta
     4321 aaattcacta cagggggaac agaacttgtt ttacaagact tacttgattc cattattcct
     4381 ggattattac cacttgtatg tactttggga atatataaat tgattaagaa aaatgttagt
     4441 acaaatatgc tcttattagg ttgtattttg gcagggtttg ttttaagtat aataggtatc
     4501 ttataatgat taaggctcta atttttgata tggacggagt tttaattgat agcgagatta
     4561 tgtatcaaaa gtgggtattt aattttttaa aacaagaaaa tttaagctat cctttgtatt
     4621 cttatcaaaa aaagattgga
//
LOCUS       DADVXV010000139         4628 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.144, whole genome shotgun sequence.
ACCESSION   DADVXV010000139 DADVXV010000000
VERSION     DADVXV010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.144"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(52..522)
                     /locus_tag="KB969_002755"
     CDS             complement(52..522)
                     /locus_tag="KB969_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBB6870665.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(681..1139)
                     /locus_tag="KB969_002756"
     CDS             complement(681..1139)
                     /locus_tag="KB969_002756"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBB6870666.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1310..2455)
                     /locus_tag="KB969_002757"
     CDS             complement(1310..2455)
                     /locus_tag="KB969_002757"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBB6870667.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2468..3385)
                     /locus_tag="KB969_002758"
     CDS             complement(2468..3385)
                     /locus_tag="KB969_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBB6870668.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3813..4376
                     /gene="efp"
                     /locus_tag="KB969_002759"
     CDS             3813..4376
                     /gene="efp"
                     /locus_tag="KB969_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBB6870669.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4477..>4628
                     /locus_tag="KB969_002760"
     CDS             4477..>4628
                     /locus_tag="KB969_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870670.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEA"
BASE COUNT         1450 a          845 c          876 g         1457 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tcttttttta tttttattaa gttaaagaac
       61 ggattcaatt gcagcggtca ttttcaatgg agaagtttgt ggtgcaaatc gttcgattac
      121 tttgccattt ctatcaatca aaaatttagt aaaattccat tttattgctt tagtgacagt
      181 accaggagct tcatttttaa gataagtaaa aagaggatct gtattttctc catttacgtc
      241 aatcaattga tgcataggga aggtaacgcc ataagtggtt ttacaagctt ctgctgcttc
      301 agtcgctgaa tctagctctt gtttaaattg attggaagga aagcctaaga taaccagacc
      361 ttgtgtctga taagcttggt aaagttcttc taattgttta aattgaggtg ctagaccgca
      421 ttttgttgca gtgttaacaa tgattatcgg tttgcctgca tattttttca atgaatagac
      481 agtgccgtct tctaaagtag tttcaaaatt ataaatagac ataaagtttt ctcctttcta
      541 ttttatataa taaaaagagc gctaaactga aaactagcta tttgttttcc cgtttagaac
      601 tcttttcaga caataaatat ttaataaaat acgaagataa gatagctata ttgcttctca
      661 tctttacgtt cttttagaaa ctatgcttct acttcagacc attcatcgcg ttttgctaaa
      721 aattcacgag ccaaagcttg tgcaccttct agtgtatggc tggcagccca gccacattgt
      781 gtttcattgc ttgcaggtac ttcagtagct tcaagaacat ctttcattgt tgcttcaaga
      841 acatctaaaa tgtcttcgta gctttcatga ttcaatacag tcaagtaaaa gcctgtttgg
      901 catcccattg gagaccagtc tacgatgtaa tctgcgtgat tgcggattag ttcggcagtc
      961 aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt ctttatttgg ttgtttaaag
     1021 cggacgtcgt atttaatgat gacatcgcca tgcgcacccg tttttcgatc agctacacgt
     1081 acataaggtg ctttgacttt tgtatggtca agattaaaac tttcgacatt cattctcatt
     1141 tgtaagactc ctatctgttt gttcattcgt tttgatgctt ttcactaaag aattatttag
     1201 tgaaatttac aaaaacgtct ttctacttga ttctaacact tatcgtttcc aaggtgtagc
     1261 aatctgaaat attttttaga tttttctgct aagtcgttta ttgggacttc tagttcttga
     1321 ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg accatactca attcctacag
     1381 aaagacggat caagccgtcc tttatgccag cctcttctcg tttttctttt ggaatagacg
     1441 catgagtcat gacagaagga atttccacta aactttctac gccacctaaa ctttctgcta
     1501 aagtaaatag ttggagtgat tcaacaaatg gaatagcaga ttcttcattt tttaaagtaa
     1561 aagaaatcat tccgctaaag ccgctcatct gctgcttagc aactccatgg agttcatgat
     1621 cgggtaatcc tggatagtag accttttcta ctgctggatg agaaaataga aaatcagcta
     1681 ccacaaaagc atttttttga tgttcctcca tacgaacact tagtgtcttg attccgcgct
     1741 gaagtaacca gctatcttgg ggaccaagta cggctccgat agcattttgg taaaatccga
     1801 tctgatcggc tagatcttta tggttagaag tcactaaacc agctactaca tcgctgtgtc
     1861 cgcctagata tttggtaccg ctatggacaa cgatatcaga accgagatct aaaggtcttt
     1921 gaaaataagg agtagcaaat gtattgtcag caataactat caatccatgt tgatgagcca
     1981 gagtggcact tttttctaaa tcagtaatct ttagaagcgg attgctaggt gtttcaagat
     2041 aaagtgcttt tgtattgggt ttgatggatt gttctatttt atcaagatta ctcgtatcta
     2101 tgatcgtgta ctcgagacca tttttagtaa gaactttgtc aaatagacgg aatgttcctc
     2161 catagacatc atctcctaat aagatatgat cgccagcttg aaaaagagaa aaaacggcat
     2221 gaatcccaga aagaccagaa gaaaaagcga atcctcgaac accgccttcc aaatcagcaa
     2281 tcagttcttc caatgcaaaa cgagtaggat taccagatct tgaatattca tattgtttag
     2341 gctggccgac gccatcttgc cgataagtgg atgtttgata aataggtaca ctgacagctc
     2401 ctgttgtggg atcttcactg atgcctccgt ggatcaattt tgtttgaatg tgcatgtttc
     2461 tttcctccta taagtaaatg ttttttgata aatagcggtc tgctgcgtct ggaaaaatcg
     2521 taacgacacg atgaccaggt ggtaaacgac gaatttctct taatgctgct gcaaaagccg
     2581 caccactcga acttccaact aatagtcctt gttctcgtgc taactgccta gtatagttaa
     2641 acccttctac atcagagatt gtctcgatct gattgattga aaggggagaa agaaacggcg
     2701 gaatgaattc tacaccgata ccctcaattt cgtgaggggc tggatcacca ccatttaaca
     2761 cagagccctc tggttctaca ccgattattc gaatgtcggg atatttttct ttcaaaaagg
     2821 tagaagttcc agcaaaggtt ccaccactcc caattcctgc tacaaaacta tggatatttt
     2881 ctttgatttc atgaaagatt tctggcccta acgtatgata gtaagcagca ggattatctt
     2941 tattttcaaa ttgaagaggc agatagctgt ttgatatctc ctctgcaagt tttttacttt
     3001 tgctgatggc accgatgatt ccttgctcac taggagaatg gatgatcttt gctcccaatg
     3061 ctttcatcaa ttgttgtttt tctaagctaa acttctctgg aacaacaaaa accgttctta
     3121 atttgtatgt gagtgcggcc agagcgatcc caattcctgt atttccggca gttggttcga
     3181 tgatcgtcgt tttttcattg atttttcctt gggcaaatcc ttctttgatc aaataactgc
     3241 ccaatctatc tttgatactt cctccaggat ttaaatattc tagttttgca taaatagcag
     3301 aacctttagg catagaatag tgctgattgt caaagcgata aagcggtgtg gaaccaatag
     3361 cttctgtaat tgtcgagata atcatgtggg cctcctaaaa aaagataata aaaaaaggag
     3421 ctgactatta aatcagctcc ttgaaagaca tagagaaaaa ttgagtagat aaaaagataa
     3481 gttacctggt actcattcta tgaagggcaa ttaatagaca tgacaaatag tatgctgctt
     3541 ttatgcacca tacaacagca acgattcaat tgtttttggt tgctgactgt catgtgtatc
     3601 cctccaagta aaatttttat taacgatagc atgaaaaaaa ataaaagtca aaggcttgaa
     3661 agaaaaaaat atttcgatag catcgtttac ccgtgtttat ttttctgaca aataggcatg
     3721 agaccttaaa agatagagaa tactctagtt ttctggccgg ttgtctgata caataaagtt
     3781 gattatgata aagaaaagaa ggagcaaaaa taatgatctc agcaagtgat ttaagagccg
     3841 gtatgacttt cgtacaagac ggcaaactga ttaaagttct ggatgcaagc caccataaac
     3901 ctggtaaagg aaatacagtt atgcgtatga aactgaaaga tgtccgttca ggtgcaacat
     3961 acgacacaac gttcagacca gaagaaaaat ttgaaaaagc acatatcgac acaaaacctg
     4021 tacaatattt gtacacgatg gatgatacag ctttcttcat ggatttggaa acatatgagc
     4081 aatatgaaat tcctgtagaa acagtagaag aagaaatgaa atatatccta gaaaacatgg
     4141 aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt tcaattacca acaactgtcg
     4201 tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc aacagtcact ggttcaggta
     4261 agccagcgac aatggaaact ggcttagtag tcaatgttcc tgacttcatc gaaacagatg
     4321 aattgttgga aatcaataca gcagaaggtt cttatgtaaa acgtgcgtca aaataattcg
     4381 ctaacggatt gataagaatt tgaaaacaga gcttgacctc ttgaaaggca gatcatcgga
     4441 tctgcctttc aagaggtttt ttgtggaatc agcaaattga aaaataaaaa agtatttgat
     4501 tttatttata ttttgaaaga tgaatggcaa aagctagaga aagaaaaaac tgcacttatt
     4561 tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc gaactattcc gaactatatt
     4621 gaagcgaa
//
LOCUS       DADVXV010000140         4620 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.145, whole genome shotgun sequence.
ACCESSION   DADVXV010000140 DADVXV010000000
VERSION     DADVXV010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.145"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            153..959
                     /locus_tag="KB969_002761"
     CDS             153..959
                     /locus_tag="KB969_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBB6870671.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            977..1684
                     /locus_tag="KB969_002762"
     CDS             977..1684
                     /locus_tag="KB969_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBB6870672.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            1681..2652
                     /locus_tag="KB969_002763"
     CDS             1681..2652
                     /locus_tag="KB969_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBB6870673.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2645..3673
                     /gene="vanB"
                     /locus_tag="KB969_002764"
     CDS             2645..3673
                     /gene="vanB"
                     /locus_tag="KB969_002764"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBB6870674.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3679..4287
                     /locus_tag="KB969_002765"
     CDS             3679..4287
                     /locus_tag="KB969_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBB6870675.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4353..4526)
                     /locus_tag="KB969_002766"
     CDS             complement(4353..4526)
                     /locus_tag="KB969_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870676.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1300 a          972 c         1230 g         1118 t
ORIGIN      
        1 attttgaccg acaggtataa ccctgccggt ctttttttgc tgctacagga aaactacaga
       61 ctggctacag ggaaagtaca gatgcgcttg ccataataac aatcgtacca gccacaaatc
      121 gtagttttat tgcaaaggag gcattcgatc aaatggaaaa aagcaactat cattccaatg
      181 cggatcatca caaacggcat atgaaacaat ccgtggaaaa gcgggctttt ctatgtgcgt
      241 tcattatttc gttcacagtc tgcacgctgt ttttggggtg gagactggct tccgtattgg
      301 aggcaacaca gataccgccc atccctgcaa ctcatacagg cagcagcact gacgtagtgg
      361 agaatttgga ggaaaacgct cttgccaccg ccaaagaaca gggagatgaa caggaatgga
      421 gcctgatttt agtgaacagg cagaacccca tccccgcaca gtacgatgtg gagcttgagc
      481 aactatcaaa tggtgagcgg atagatattc ggatttctcc ctatcttcaa gatttgtttg
      541 atgccgcaag aactgatgga gtttacccga ttgtcgcatc cggataccga acaacagaaa
      601 aacagcaaga aattatggat gaaaaaattg ccgaatataa ggcgaaaggc tacacctctg
      661 cacaggctaa agcggaagca gaaacttggg tggccgtgcc gggaacgagc gagcatcagc
      721 ttggtcttgc tgtggatatc aatgcggacg gaattcattc aacaggcaac gaggtttata
      781 gatggctgga tgaaaacagc tatcgttttg gttttattcg tcgctaccca ccagacaaga
      841 cagagataac cggtgtgagc aacgagccgt ggcattaccg atatgttggc atcgaagctg
      901 ccacagagat gtacaaccaa ggggtttgcc ttgaggaata tttaaaacca gaaaaatgag
      961 aaaaggatgt tatgttatgg acagaaaaag attgacacag cgtttcccgt tcctgcttcc
     1021 aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga atgagatttg acggctgtcg
     1081 ctatgcgcag acgatagggg aaaaatcgct ttcccatttg ctctttgaaa cggattgcgc
     1141 attatacaac cacaataccg gatttgacat gatataccag gaaaacaagg tgttcaactt
     1201 aaagctggca gcaaagacct taaacggctt attgataaga ccgggggaaa ccttttcttt
     1261 ctggttgttc ctgcatacgc cattgacaat tatccagcgc agaggtcacg aagtaaagga
     1321 gtttccagag ccaaacagtg acgagattaa aggggtggat gcaaccattt cagagggctg
     1381 gattgattta aaagtgcgaa acgataccga ctgcacctac caaatatggg tgaccttaga
     1441 tgatgagaaa atcatcggtc aggtgttcgc cgacaaagag ccccaagcat tatacaaaat
     1501 tacaaatggc agtatccagt atgtccgtga aagtggcggg atttatgaat atgcccaggt
     1561 taaacggatg caagttgcct taggtaccgg ggaaataata gattgcaagc tgctttatac
     1621 aaacaaatgc aaaatctgtt atcccctccc ggaaagtgtg gatattcagg aggagaacca
     1681 atgagaaaaa gtgtgggcat tactgttttt ggatgcgaac aggatgaggc aaatgctttc
     1741 cgcgctttat cgccggattt tcatattatc cctacgctga ttagcgatgc gatatcggca
     1801 gacaacgcaa aattggccgc tggcaatcaa tgcgttagcg taagccataa gtccgaggtt
     1861 tccgaggcga caattcttgc gctgagaaag gtcggggtaa aatacatttc tacccgcagc
     1921 atcggctgcg atcacattga tacgactgcc gccgagagaa tgggaatctc ggttggcacg
     1981 gttgcgtatt cgccggacag cgttgcggat tatgctttga tgctgatgct gatggccata
     2041 cggggtgcaa aacccaccat gcacgccgtg gcgcaacaag atttcagatt ggatcgtatc
     2101 cgggggaaag aactggggga tatgactgtg ggagttattg gaaccggcca tatcgggcaa
     2161 gcggtcgtca aaaggctgcg gggatttgga tgccatgtgc tggcctatga taacagccga
     2221 aaaatggatg cagattatgt ccagcttgat gagcttctaa aaaacagcga tattgttacg
     2281 ctccatgtgc cgctttgtgc ggatacccgc catctgatcg gtcagaagca aattggagag
     2341 atgaagcaag gcgcattttt aatcaacacc gggcgcggag cgcttgtcga taccggggcg
     2401 ctggtggagg cgttggaaag cggaaagctg ggtggtgcgg cactggatgt gttggagggc
     2461 gaggatcagt ttgtttatac cgattgctcg cagaaagtgc ttgaccatcc ctttttgtcg
     2521 cagcttttaa ggatgccgaa tgtgatcatc acaccccata cggcgtacta cactgagcgt
     2581 gtgctgcagg atactacaga aaaaacaatc aggaattgtc tcaattttga aaggagttta
     2641 cagcatgaat agaataaaag tcgcaatcat cttcggcggt tgctcggagg aacatgatgt
     2701 gtcggtaaaa gccgcaatag aaattgctgc gaacattgat acggaaaaat tcgatccgca
     2761 ctacatcgga attacaaaaa acggtgtatg gaagctatgc aagaagccat gtacggaatg
     2821 ggaagccgac agtctccccg ccatactctc cccggatagg aaaacgcatg ggctgcttgt
     2881 catgaaagaa agcgaatacg aaacacggcg tattgatgtg gctttcccgg ttttgcatgg
     2941 caaatgcggg gaggatggtg cgatacaggg gctgtttgta ttgtctggta tcccctatgt
     3001 gggctgtgat attcaaagct ccgcagcttg catggacaaa tcactggcct acattcttac
     3061 aaaaaatgcg ggcatcgccg ttcccgaatt tcaaatgatt gataaaggtg acaagccgga
     3121 ggcgggtgcg cttacctacc ctgtctttgt gaagccggca cggtcaggtt cgtcctttgg
     3181 cgtaaccaaa gtaaacggta cggaagaact taacgctgcg atagaagcgg caggacaata
     3241 tgatggaaaa atcttaattg agcaagcgat ttcgggctgt gaggtcgggt gtgcggtcat
     3301 ggggaacgag gatgatttga ttgtcggcga agtggatcaa atccggctga gccacggtat
     3361 cttccgcatc catcaggaaa acgagccgga aaaaggctca gaaaatgcga tgattacagt
     3421 tcccgcagac attccggtcg aggaacgaaa tcgggtgcag gaaacggcaa agaaagtata
     3481 tcgggtgctt ggatgcagag ggcttgcccg tgttgatctt tttttgcagg aggatggcgg
     3541 catcgttcta aatgaggtca ataccctgcc cggttttaca tcgtacagcc gctacccacg
     3601 tatgatggcc gccgcaggaa tcacgcttcc tgcactgatt gacagcctga ttacattggc
     3661 gttaaagagg tgataagtat ggaaaatggt tttttgtttt tagatgaaat gttgcatggc
     3721 gtccgttggg atgccaagta cgccacatgg gataacttca caggaaaacc ggtggatggg
     3781 tatgaggtga atcgcatcat cggcacaaag gccgtggcgt ttgctctgcg cgaggcacaa
     3841 atccatgcgg ctgcgcttgg ctatggcttg cttttatggg atggatatcg gccaagaact
     3901 gcggtggact gcttcctgcg ttgggcagcg caaccggagg acaatctcac aaaagaaaaa
     3961 ttttacccca atatagagcg agccgagttg attacaaagg gttatgtggc ctcacaatcc
     4021 agccatagcc gtggaagcgc aattgatctt acgctctacc acctggatac aggggaactt
     4081 gtttcaatgg gaagtaactt cgattttatg gacgaacggt cgcatcatac agcaaaaggg
     4141 ataggggatg cagaggcaca aaatcgaaga tgcttgcgta aaatcatgga aagcagcgga
     4201 tttcagtctt atcgctttga atggtggcac tataagttga ttgatgagcc ataccccgat
     4261 acctatttta attttgccgt ttcataatga aagtattggt tttgtatcag attttggatt
     4321 tgataaaatc tatgctggtc atggacaatc ttttactgga aagtggttaa agcatctttt
     4381 gtaatacatt gcaaattata gtattcaatc tgcccagcgg cagaaaagaa aaaaaccgct
     4441 gttgggcaga cctttcccac gcccattttg tattttgctg gcggcggttt tgagaaatca
     4501 aggccgccgt tcttttctgg cagcaaaagg tgtggcggcc cataggagga tgccgctatg
     4561 ctgttttgct attgccatgc tctaatccac ttccaccact caaaaaaagc cttgcccctc
//
LOCUS       DADVXV010000141         4591 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.146, whole genome shotgun sequence.
ACCESSION   DADVXV010000141 DADVXV010000000
VERSION     DADVXV010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.146"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            186..2855
                     /locus_tag="KB969_002767"
     CDS             186..2855
                     /locus_tag="KB969_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBB6870677.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="KB969_002768"
     CDS             complement(2946..3566)
                     /locus_tag="KB969_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBB6870678.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="KB969_002769"
     CDS             3680..4219
                     /locus_tag="KB969_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870679.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="KB969_002770"
     CDS             4216..4554
                     /locus_tag="KB969_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBB6870680.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1420 a          790 c          860 g         1521 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgacatt t
//
LOCUS       DADVXV010000142         4453 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.147, whole genome shotgun sequence.
ACCESSION   DADVXV010000142 DADVXV010000000
VERSION     DADVXV010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.147"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..115)
                     /locus_tag="KB969_002771"
     CDS             complement(<1..115)
                     /locus_tag="KB969_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBB6870681.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="KB969_002772"
     CDS             246..698
                     /locus_tag="KB969_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870682.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="KB969_002773"
     CDS             712..1401
                     /locus_tag="KB969_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870683.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="KB969_002774"
     CDS             1526..3877
                     /locus_tag="KB969_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBB6870684.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="KB969_002775"
     CDS             3957..4352
                     /locus_tag="KB969_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870685.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT         1565 a          573 c          885 g         1430 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tat
//
LOCUS       DADVXV010000143         4444 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.148, whole genome shotgun sequence.
ACCESSION   DADVXV010000143 DADVXV010000000
VERSION     DADVXV010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.148"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..244
                     /locus_tag="KB969_002776"
     CDS             <1..244
                     /locus_tag="KB969_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBB6870686.1"
                     /translation="TIYDLVKHGIPMEELNIGGIAQKNPDTDLLVTKSVYLNKSDAEK
                     LKEMNEQYGVKNIYFQATPSAPKTGLKDVLNKFDLS"
     gene            281..682
                     /locus_tag="KB969_002777"
     CDS             281..682
                     /locus_tag="KB969_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870687.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            794..1147
                     /locus_tag="KB969_002778"
     CDS             794..1147
                     /locus_tag="KB969_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870688.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            1181..1624
                     /locus_tag="KB969_002779"
     CDS             1181..1624
                     /locus_tag="KB969_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBB6870689.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            1641..2726
                     /gene="uxuA"
                     /locus_tag="KB969_002780"
     CDS             1641..2726
                     /gene="uxuA"
                     /locus_tag="KB969_002780"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6870690.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            2719..3432
                     /locus_tag="KB969_002781"
     CDS             2719..3432
                     /locus_tag="KB969_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBB6870691.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(3639..3788)
                     /locus_tag="KB969_002782"
     CDS             complement(3639..3788)
                     /locus_tag="KB969_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870692.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            4184..4384
                     /locus_tag="KB969_002783"
     CDS             4184..4384
                     /locus_tag="KB969_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBB6870693.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         1565 a          676 c          946 g         1257 t
ORIGIN      
        1 aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata ttggagggat
       61 tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt taaataaatc
      121 agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata tttattttca
      181 agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc
      241 ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga acgagctgtt
      301 tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa
      361 acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag atgtgacagt
      421 cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag atatcgaaaa
      481 agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag gaagttattt
      541 catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat tgtccttcat
      601 tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc ctcatcacgt
      661 attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga gctacttttt
      721 cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc gaaatacttc
      781 atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg tagcgtatgc
      841 gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat cgggtatgaa
      901 aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc tacagttttc
      961 gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa
     1021 aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa
     1081 aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta ttgctctttt
     1141 tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa tcatgatcgt
     1201 tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg tcgggacatc
     1261 gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat tcggagagaa
     1321 ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat ttgttgatct
     1381 aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga ctgaagaaaa
     1441 gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag aagcaatcaa
     1501 tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca aacaaggaaa
     1561 agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg aggacgattt
     1621 ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa aaaggggatt
     1681 cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt ggaactttgc
     1741 tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg aaagcatctg
     1801 ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca
     1861 aggcagggac agatgaacga gattactata ttgataacta tatacgaaca atcaaaaact
     1921 tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt ggatgggcga
     1981 aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac gatcagaaaa
     2041 tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag tcaaagggat
     2101 tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt
     2161 atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta gaaaaagtga
     2221 ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat ccgccatggg
     2281 aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa attctaaatg
     2341 cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg gcaaatccgg
     2401 aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt gtccacttca
     2461 gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc tctacagaag
     2521 gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc gacggtccta
     2581 tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga tatggcctgt
     2641 atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata agtaaggaaa
     2701 aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat ggatggcctt
     2761 ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca aaagtatgat
     2821 tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat ggcgataaga
     2881 gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg agaagcaatc
     2941 aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa aaaaggagca
     3001 gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc ttcgtctaat
     3061 acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa
     3121 atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt tttgaaagct
     3181 tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc gattgcaggg
     3241 atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca tttgataggg
     3301 ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata tgaatccaat
     3361 aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga aagtaaaggg
     3421 ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc ctgcacgact
     3481 gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt atttgtagtg
     3541 aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat gcgtttaaag
     3601 agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt ttttaattct
     3661 tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc tttgtcaaaa
     3721 acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc tttgttatag
     3781 aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa cgcgttgata
     3841 acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta agaaatttta
     3901 aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa tcaatcgcgg
     3961 ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta tatttcattg
     4021 cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct attttgaaac
     4081 gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa tatttattgc
     4141 aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata acggtacagt
     4201 aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg gaaatgatgt
     4261 atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag aaggccaagc
     4321 agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca ttgttaaagc
     4381 ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt ttgtacgaaa
     4441 aaat
//
LOCUS       DADVXV010000144         4433 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.149, whole genome shotgun sequence.
ACCESSION   DADVXV010000144 DADVXV010000000
VERSION     DADVXV010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.149"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(543..2048)
                     /locus_tag="KB969_002784"
     CDS             complement(543..2048)
                     /locus_tag="KB969_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBB6870694.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDPFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="KB969_002785"
     CDS             complement(2045..2731)
                     /locus_tag="KB969_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6870695.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="KB969_002786"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="KB969_002786"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBB6870696.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          730 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa agggatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DADVXV010000145         4369 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.150, whole genome shotgun sequence.
ACCESSION   DADVXV010000145 DADVXV010000000
VERSION     DADVXV010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4369
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.150"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            41..922
                     /locus_tag="KB969_002787"
     CDS             41..922
                     /locus_tag="KB969_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870697.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            935..2545
                     /locus_tag="KB969_002788"
     CDS             935..2545
                     /locus_tag="KB969_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBB6870698.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2622..3281)
                     /locus_tag="KB969_002789"
     CDS             complement(2622..3281)
                     /locus_tag="KB969_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBB6870699.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVALYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3564..4229)
                     /locus_tag="KB969_002790"
     CDS             complement(3564..4229)
                     /locus_tag="KB969_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBB6870700.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT         1168 a          853 c          869 g         1479 t
ORIGIN      
        1 ttgtttagta tatattttta gaaaaaggag tggggttttt atggcagaaa tcgtcaaagt
       61 cacacatttg aaaaagagct ttggtcgttt cgaagcttta aaagatgtct ctttcaccgt
      121 acattcaggt gaagtcgttg gatttatcgg accaaatggt tctggaaaat ccacgacgat
      181 tcggacactt ttagggatta taaaaaaaga cggcggaacg gcaacgattt ttgggcaaga
      241 tgtatgggaa gatagtttat ctatccatga acgtctttct tatgttccag gcgatatctc
      301 tttgtgggga aatttgactg gaggagcgat catcgatctc ttcatgaagc ttcatggaaa
      361 agggagtgct caaaaaaaag atgaactgat tcaacgtttc tctcttgatc ctaagaaaaa
      421 agcaaaaaac tattcaaaag gaaatcgcca aaaagtgggc ttgattgctg ctttggctgt
      481 tgattcggat ctctatttat ttgatgagcc tacttctggt ttagatcctt tgatggaaac
      541 gattttccaa gaagaagttg aaaaattgaa agaacagggc aaatccatcc tactttcttc
      601 tcatattctc agtgaagtcg agcgactagc ggataaagtc gtgatcatac gcgaaggaac
      661 actcgatgaa gaaggaacac tcgatgaatt gcgtcatttg actcgttcga ccatcactat
      721 agaaacagaa gcagagaata gtcacttagc acaattgaac ggtgtccatg actttgtgca
      781 aaaaggtcac ctcgctcaat ttgctgctga taacgaagct ttcgatgtga ttttagctga
      841 agcgtccaaa ttaggtgtga aaaaatttga atctattcca ccgactcttg aggatttatt
      901 catgagacat tatgaaggat gaggaggaag cgaaatgact gataaatttt cacgctggtc
      961 cacccttttt tctcaaaacc ttagccgtga ctggaaaaag atcctgatat ggctagtcgg
     1021 tgtcactgct ttttctggtg gttttgtccc tgcgtttgaa gaattgactt ccggacaagg
     1081 attagctgga ttatacgaaa ccttgcaaaa cccggcaatg attgcaatgg tcggaccaac
     1141 tccagcttcg aatgctgctg agtatacttt aggagcgatg tatgcaaatg aaatgttgct
     1201 tttttgcagt ttgtttgctg ctgtgatctc tgttttacac gtggtgagcc aaacgagaaa
     1261 aaaagaagaa cttggtctga ttgaacttat tcgttccttt cgagtcggac gtcaagcaaa
     1321 ctctttagct gtcatcgctg aaagtattct gatcaatttg cttttagcaa tatcgatcag
     1381 ctgtacgatg atttttttcc aagcggattc gatcactgca gaaggtgctt ggctttttgg
     1441 gctatctgta ggtagtatgg ggattttggg gagtgccgtt gcactgtttg ctgcacaact
     1501 gatgccaagt tcagccagtt cgaatggtct gtctttagcg tttttaggtg gactttacct
     1561 tctacgagca ataacagatg tagctgattc ctccctttcg atgtggaatc ctttaggctg
     1621 gtcttatttg acctatccat ttacaactaa caactggatt cctttgcttt atttgttttt
     1681 gttcagtcta atcttgataa tcagttcatt tgttttagag gaacatcgag atttgaacac
     1741 cggctatatc cccgaacgtg aaggaaaacc gtatgctaaa cgttctcttt tatccttgcg
     1801 tggtttatta ttctatctaa ataaagggat gacaatcagt tggcttatca cttttggttt
     1861 gatgggggcg gcatacggct ctatctacgg gaatatgcaa cagtttttag aaagtaacga
     1921 cttaatgaaa cagatgttta tccaatctgg cgtctcaatt gaaaaaaact ttacaagcac
     1981 gatcatggta gtcttgattt gtctagctgc tattttacca attgctagca tcaatcgttt
     2041 atttacagaa gaaacccacg gacgtatgaa tcagctgttc gcaacaaaaa tttctaggaa
     2101 ccaactttat tggaccaata tgttactagc tattctattt gctatattgg caatcctgat
     2161 tagttctggt gcactagggc tttctgcttt ggcttcgatg aaggatgcga aagacatgga
     2221 tctattgatg tttcttaaag ccgggttcaa tttcctgcct gccgttttag tgtttatcgg
     2281 aattagtggc tttctattcg gatggcttcc tcgaatcggt aaacttgctt atatctactt
     2341 agcttactcc tttgcactca attactttgg cggaattttg gatttaccag aatggttttc
     2401 caaaacagct gtccctagct gggttccacg gatgccaaac gattcttttg atctttccgt
     2461 gttccttacg ttatcatgta tcagccttgc actgttcgtc cttggttcta ttggttatag
     2521 gcgaagagac ttactagaag gataataaaa aagcatgtac aatttcatgc tagcctccaa
     2581 atctgggtca aaaatccaac atttggaggt cattttttta tttacaagtc ttctaactgc
     2641 tctttatcaa tgatccagac ttctcgattc tttcttttta cataaccatt ctcctctaat
     2701 aatttaaatt ttctagataa agtttcgggg gtcgtaccga taaatgcagc aagttctttc
     2761 attttcattg gcaggaaaaa gtgatccttc cctgtcgctt tagctaagtc aagcagatag
     2821 agagcgactc gttcttctac tttttccatc atcaaaaaag ttgtctgctg ctgtactttt
     2881 gttaatttct caacgttgat tgctaaaagt ttcagactaa gggcgggata atgcagtaag
     2941 agttccgaga aatctttttg tctcaatatg caaatttccg ttttttctag tgcttcgcca
     3001 aataaagact catttggaac gcctagcaac tggctctctc cctcatatcc gcccggctct
     3061 attactcgta aaagctgttc ctttccgcta gcagataatt gatacacttt catactgccg
     3121 gaggccacga tcactaattg aggttctcca ttcggcgcaa gaatctgttc tcctttttcc
     3181 acatagtgat gtttgacaag tgcgtgtact ttttcttgat cttgctgtac taagtgattg
     3241 aacaaaggaa caaatgaaac acataaatga tcatgactca taatctctcc tccttctaaa
     3301 cagctatttc taataaagaa acataacttc ccttattcca actgataatt ttcttttatc
     3361 atagcataaa cgtcaagcga accagatacc agcaaataga gtggatttct ttttgtccct
     3421 tgctttattt tccttctttt gagaccttaa gtaattgatt cctatcaatt ttttaaatat
     3481 ttactttttg aataatcaaa aacaaacctt cactcgcaag ccgagagtaa ggtttgtttt
     3541 tcgcattgct tatttcgtgt tgtctattga aatttttccg cacctagctt ttgatatagt
     3601 ggtgctagtt cttgtaaggt ttcagcggtt atttgctcaa cgtgttcgat ttcttgcgga
     3661 tagaagaata gtttacccat ttgaaaggtt cggtctctca tcgctttttt caactcttct
     3721 tgtttctttg tatcggacaa atagtcagac aaagctaagt ggtcgtcaag ttcatgttct
     3781 ggttgcggcc atatgtaata atccttgata tcgactgttt tgctccactc tttcagtatc
     3841 gcaagcaact ggttatacgc tgcaatgcta ccatatcgtt cttcgctttt ataatgttgg
     3901 tacatcaaat agatttggta ttgtttttga ttcaacaaaa ctgctagaca ggcattctcg
     3961 tcttgacgag attcgcttcg gtacgcgctc caaaaatgac tgcgtaaatt ccagccattc
     4021 gtccagcttt cgattttagg tttgctcatg ccgtacatat caggcaaaag tgcagctgtc
     4081 tggagctgaa tctctttcca tttttgccag tgttctttat attctttctt gatttgttca
     4141 atcttatctg ttggatggct ctctttgagc tgtttgaatg cgtagattgg tcgatcaaac
     4201 aactgataat ctgattttcc aagttccatt gtttcgcctc tttccgttat cttttgtatt
     4261 ctacctgaat tttgcgatat ggacaaatag aggttgtgaa aaagctgttc tgcatcaagt
     4321 cataagaaca gccaaacaaa aaactgcgat gagcatcacc gcagtttta
//
LOCUS       DADVXV010000146         4352 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.151, whole genome shotgun sequence.
ACCESSION   DADVXV010000146 DADVXV010000000
VERSION     DADVXV010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.151"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(105..590)
                     /locus_tag="KB969_002791"
     CDS             complement(105..590)
                     /locus_tag="KB969_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBB6870701.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(592..1356)
                     /locus_tag="KB969_002792"
                     /pseudo
     CDS             complement(592..1356)
                     /locus_tag="KB969_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1526..2719)
                     /locus_tag="KB969_002793"
     CDS             complement(1526..2719)
                     /locus_tag="KB969_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6870702.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(2803..3003)
                     /locus_tag="KB969_002794"
     CDS             complement(2803..3003)
                     /locus_tag="KB969_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBB6870703.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            complement(3427..3660)
                     /locus_tag="KB969_002795"
     CDS             complement(3427..3660)
                     /locus_tag="KB969_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870704.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(3667..4098)
                     /locus_tag="KB969_002796"
     CDS             complement(3667..4098)
                     /locus_tag="KB969_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6870705.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         1092 a         1073 c          842 g         1345 t
ORIGIN      
        1 cagtttgatg aattaactga taaaaaaata tctactattt aaagatacag ggataagtaa
       61 gtaaaaaaat aacatgtcat tagatagtag acagttccaa ctctttattt accttttttg
      121 tatgctgcac tgtcaatcca agttcctaaa ttgttgtatc catcatcact tatataatca
      181 tattggccat caataatttc gtcaaaccac aaatattctc catctggttt ttgcccaatt
      241 attttaatta ctgattgact agtagttgtc atctggttaa aatcttttat tttacctata
      301 ttaacggcca aaatagcatt tcctcgctta taactctcct ggatttcata tttaacatat
      361 tctcgatcaa gagtttcttt acctatcagc accacagtca ctgatgttcc aattaattga
      421 ttatctatcc agttttttat agcaatatct ccattacgtt taactttctc aaattcagcc
      481 ttatctacaa aaccagcttc ctttgttcct cgcaaagtcc agctgtttct aactaccatt
      541 gctcttgtta catctgcata atggaaacta aaaaaaaccc ttctcaccat attaatcctc
      601 ctgaatacta tttattaaac tgacaatttg ttcaactttt ttatctactt ctccttcagt
      661 atctaatttt tctagcgctt gaaatttact ttttaaggaa tcatcaaaat aatcactgaa
      721 attctcttga atcttatcaa acaaaacctt acttgcacct ttggtaaatc caatcggaac
      781 tactatattt tcattttgaa cagataattc aaattcttca atcattccat ctgctgtaac
      841 tatttcacct gattcaagtt tgtttccaaa aacaaaaata ctaatcccag actctgcaat
      901 aatgttttct cgatatcttc tccactcatg aggcatatca aggggaagtg gtcttaaaga
      961 aagtacgtct tgtatgttat tttttcttaa atttcttctc tgctttagaa ctcctgaaac
     1021 aatactatta ccaattccaa gtccgtaacc tgatactatt ctataaccgg attcagaaag
     1081 cctatatgct aatttctcga caaattttaa tcctttcgat tcagatgtaa atggagtata
     1141 atcaacagca cttcccgaaa taaaaatagt ttttctcaaa tacttttttc taatactttt
     1201 caaaatatca gtaatctcag aataatcatc tacttcaaca acgtttatcg aaaatctgga
     1261 caaatcattg atttgtagtc ttctttttgt cagttcataa ttatatctct cttgatcaaa
     1321 aaaatcctca gaatcgacaa aattttcctt taaaattata tgggatttta gattatcttt
     1381 ttagaagttc ttgaatgtcg gtatagcccg tgtttccggg cttttccggc atttttgata
     1441 ttgttagata cttacaaatg ttcttattac ctctcaccat ttccccctca aaagtagtaa
     1501 atggagtagt aaaaccggcc ttgtgtcagg ctgccagccg ttccatttct gcccttgcgg
     1561 aatcgaatgt ggcgtgtgca taatagttca gcgtcatggt gatattggaa tgtcccataa
     1621 tgtactgcaa ggctttgggg ttcattcccg cattggctaa ccgggtgcag aatgtatgac
     1681 gcatagcatg gggcgtcgtc gttttcggca acgcttcttc atggctcttg ttgtacttct
     1741 tcacaagcct gccaaacatc ccgccataat ctaccgccgt catgggatag ccgttctgtt
     1801 tgagaaacag gaaattggca tacccgtcaa taatgaacgg ctttgcacct ttgcggtttt
     1861 ttatcactcg ctggaacgcc tgatacactt cctcattcat ggggattttt ctgacgccgc
     1921 tttgggtctt gggttcgtca atatagtaac cgacgccggt atttctcaaa agctggtggc
     1981 tcacgatgat tacccggttt tcaaaatcca aatctttgtc cgtcagtccg cacagttccg
     2041 aaatgcgaag ccctgtcccc agcagaataa cgattgcgtc ataatgcttt tggtaaacct
     2101 tatcaccttg aataaaggac agaaaacttt cttcctgtgc tggtgtaaga ggcacctttg
     2161 gttccgtatc gtcgtccaga acgtcactaa gctggaagtc aaacgggttt tttcggatgc
     2221 aatcgtcctg tatggcggtg taaaaagccg ctttcaggga acgcttgtcg ttattgatgg
     2281 tcttataaga aaggcccttt tctttcatcc gaagcgccca ttcctttgcg tcggacagct
     2341 tcacactgtc aatcgggcag ctccccagcc gatcttgttc cagaatacgc atcagccgtt
     2401 cccggcccag tttggtgttg tgcttcacat tgccccggtg cctgatctgc ttggcgtaga
     2461 gctggcagac ggtcattttc ttgccgatgg tgtctatccc gtcgtcaagg tctttctgga
     2521 tttctttctc cttttcccgg agtgaaatat cctcccgttt acctgccggg gtcttatccg
     2581 taggcactaa cttccatgag taaacaaact gcggttttcc aaaggtatca acatatttgt
     2641 aagcatatcg tccgtctttt ctctggctct ctccagaccg caaaacgcga tttttgctgt
     2701 ctcgtctttt ttctgacatc tcgtcatgct cctttccatg acggaaagag ccgcatatat
     2761 gcttataaat tattataaca tatctgcggc cctttttcac tattagattg tgtccaaagt
     2821 gtcaattatt ttctcaaact gcttgcgttt gatctggatg cggttgccat tcataatgac
     2881 ccagccagag gccggatttt cctcggccag cttacgcaat ttgttttctc cgatacggaa
     2941 atatttagac gcttcctcaa tcgtcagcgt gtatttttcc caaataggca catcatggtt
     3001 cataatgcag ccccctttca caaattcaaa ggtttgtgtg atttaggggc atagacggac
     3061 ggctgctggc acagctccac gggactttca cccccgcgtg gttctcacgc ggccctaccc
     3121 attgcctgcg acgcttttaa cgctcggact gtggctataa gggagtatca tagtcctgcc
     3181 tgtacgtcgt cgcccgcaag ccgccacgct cacattgcgg cgtggtgttc ctcgctccgc
     3241 ttttcccgta gggaaaagta tcatggcgca ccagccgtcc ggctcggcac agacagaatg
     3301 tgtccgtatg ccctatgatg cgccgccgtt atcttgcggg catatttatc aaggtgcgat
     3361 caggccaccg ggaaaacacc gaaacgggga aagggtaagc cgtttcatgc tgccggggcc
     3421 ggttcgtcag ttcgtgacga tagcgtggat gagcttgatt tccagacggc gcttcatggc
     3481 ctcgtccaga cacacatgcg gatagccgtt ttcgtcatag agcgtccggg tacacagctt
     3541 gttcatgtaa ccgctgtaat actgcaaaac gcgctctacg gctccggcat ccccagcgcg
     3601 ggcggcctcg atcaccgaaa ggggcaaaag ctcaatgccc ttgtagttcg ggttcttcat
     3661 ccgcgtctaa cctcccttcg gcatcaacgc ctttagctgt ttccgcagct ccgataaggt
     3721 atttgtcctg tgccgctgaa cggcactccg ggacattccc acaaggccgc cgatctcacc
     3781 atctgccata tccagaacac agtgcaggat taaaatactc tgctccatgc tgggcagcgc
     3841 ggcaaaggct tcggcaacaa gctcattgtt gatatgtagg tcatagccat gcgacgaaaa
     3901 cgtaaagctg tcgctggggt agtgatctac tgtacagagc ttgtccaaat ctgcctgtga
     3961 caaagagctt agtgacactt cacggtcacg gcggcgcttc atttcagcca agtagctttt
     4021 ggcctcgtta cgcagtaccg tcttgcaaaa agcatcgaac atgcaccgcg cttcatagtc
     4081 gcgggggata gcatccatct tctcaccccc tttctgtggg ggacttaggt ggttctctcc
     4141 ctttccgcta acaagacttt gacaaggccg ccagctaccc gctaaatacc tcctttttga
     4201 aaatttctca aaaaattttt ttggggacag ccgggccgca aaagacgaca aaaatcgccc
     4261 ggcaggtcgc aaacctaccg ggcgagaaaa tgctttgcta tgctgctgat ttacatggta
     4321 tagtacatac tcataaccgg aatagccctg tg
//
LOCUS       DADVXV010000147         4320 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.152, whole genome shotgun sequence.
ACCESSION   DADVXV010000147 DADVXV010000000
VERSION     DADVXV010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.152"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            107..562
                     /locus_tag="KB969_002797"
                     /pseudo
     CDS             107..562
                     /locus_tag="KB969_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            659..2908
                     /locus_tag="KB969_002798"
     CDS             659..2908
                     /locus_tag="KB969_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBB6870706.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            2911..4086
                     /locus_tag="KB969_002799"
     CDS             2911..4086
                     /locus_tag="KB969_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6870707.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4089..>4320)
                     /locus_tag="KB969_002800"
     CDS             complement(4089..>4320)
                     /locus_tag="KB969_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6870708.1"
                     /translation="KNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKGL
                     ESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1507 a          627 c          782 g         1404 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatc aggacaatct
      121 agtcagtgaa ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc
      181 agctagttat ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac
      241 aattgaaata atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag
      301 tctatcgata cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat
      361 aaaagagtat attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga
      421 atattcaatc cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa
      481 agcctttaag aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct
      541 aggaatcatt aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa
      601 acgcttacta tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat
      661 gtataaggat aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt
      721 taatcaggag ataagttaca tttttaagat atcggaagat ggtaaattat tgcatttata
      781 ttatggtgag aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc
      841 tatgacaacc tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga
      901 atttcctgaa tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa
      961 tggctctcgc ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa
     1021 actagaaggt ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt
     1081 ttatatttta gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga
     1141 ttatcctgtt attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat
     1201 cgagaatatt agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt
     1261 atctggtgct tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca
     1321 atcaatcgaa tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa
     1381 aagaaaaaat actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg
     1441 aaacttctta attcaagcag aagtagatac atgggatgtt actagactac aagttggcat
     1501 caatccattt ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc
     1561 gattctggtt tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt
     1621 tagaaaacgc ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa
     1681 ttgggaagca acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc
     1741 atttgatgtt ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa
     1801 cgattgtgca ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg
     1861 cagcctttca gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga
     1921 aatggtgaat aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc
     1981 taatcgaaaa cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt
     2041 tgttgaaaat attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat
     2101 taagtgggat atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca
     2161 acaaggagaa gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat
     2221 aacaaaatat cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc
     2281 tggaatgctt cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag
     2341 gttaaaaatt caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt
     2401 atcaattgtt ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt
     2461 agcttttttt ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt
     2521 gaggattgta aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg
     2581 tactttttat agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt
     2641 tagtcatgat aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc
     2701 tccttaccgc cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca
     2761 aaatagtttg cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc
     2821 tagtggacaa ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat
     2881 ttgggttata acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa
     2941 ggagcaatct taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt
     3001 ccacaaatga aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca
     3061 ccaagtataa ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga
     3121 atgaaaaaga caataatttt aggtttatta ttagctggta taggaggaat tattccagta
     3181 tttacagcta ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga
     3241 gtatataatt cattggctgt gacatatatc agctctttat actctggcaa tactagagca
     3301 acgctattag gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt
     3361 gctggagttt tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt
     3421 cctgtagctc tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata
     3481 cctgaaaatc atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca
     3541 atcttactcg taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa
     3601 attaaagggg taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata
     3661 ctagcaggat ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg
     3721 ggaattatat tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg
     3781 ttcctgctaa cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc
     3841 tttagtaact tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt
     3901 tttattggct gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt
     3961 ctaacaagaa gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg
     4021 atcctatttg taacattttt tgcgacaaat aaaaaaaata ctagagtaac ccgtggtgct
     4081 agttaatttt aatatcctaa agaatatctc aaagttcctt caaaacgtcg ttgtgctcga
     4141 cttaatagaa cactgtaagc cagtaatatg ctttcaaatc tactctctag ccctttaaca
     4201 gaacgtgagt tgaaattttg acaacctaat ttttctaagg aagaaaaaac agtctcaact
     4261 gtttttcttt gttttccaag taagctgtgg tctagttttt ctgatttatc catgttttta
//
LOCUS       DADVXV010000148         4209 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.154, whole genome shotgun sequence.
ACCESSION   DADVXV010000148 DADVXV010000000
VERSION     DADVXV010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.154"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            75..503
                     /locus_tag="KB969_002801"
     CDS             75..503
                     /locus_tag="KB969_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBB6870709.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            490..732
                     /locus_tag="KB969_002802"
     CDS             490..732
                     /locus_tag="KB969_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870710.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(1032..1247)
                     /locus_tag="KB969_002803"
     CDS             complement(1032..1247)
                     /locus_tag="KB969_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870711.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            1354..1668
                     /locus_tag="KB969_002804"
     CDS             1354..1668
                     /locus_tag="KB969_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870712.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1772..2950
                     /locus_tag="KB969_002805"
     CDS             1772..2950
                     /locus_tag="KB969_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBB6870713.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            3353..3646
                     /locus_tag="KB969_002806"
     CDS             3353..3646
                     /locus_tag="KB969_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBB6870714.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1443 a          627 c          818 g         1321 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga aagtatttgg
      481 gtgtcaaata tgaagcaaaa taaacgatat ataccattca taccactaac gacaatcaaa
      541 gccgcagctt ctggtgattc aattgccatg tccatcgttc tgtcaaaata tcaaaattat
      601 atttcacggt tagccatgaa accagtttat gaagaagaaa aaggaatggt tatgtatgta
      661 gatgaatata tgcgtagaca actggaaaca aaattgattg agaagatact tgaatttgat
      721 acaactcgtt aaagtatttt ttccctttcc ttttcattct atggaagttt tttatcgggt
      781 caaaataaag gatttccata ggctgaaaat agcctagcgc tctttgacaa atgaatagca
      841 aatctatcag tacatgtaga ttttgattct ctagttacgc catgacaagg ttagctttta
      901 agcgacaaat tttaatatga gaatcgcgac tacgataatg atacttccgt aaccaaatcg
      961 gcccgccatt actgggggga ggtgagattc ctatgtgctt tggcaaaaca gctgatagat
     1021 cagaaaaact actatttcca tatttcgatt ttggttggca tatttttcat gccaaattct
     1081 gtgattttaa tagcatcggc aagatttaat ttttcttcag ctctctctcc acttttaagt
     1141 ttttttactg tactcaagtt gattcctgtt ccgaatgcta ttgcattagc cgtagatttt
     1201 tcaagaattt ctttaattat ttttatgtct gcaattcctt gtttcatatt aaaaattcct
     1261 cttttctagt ccgttttgat ggagtactgg agtgtttttt tacaatttta aggggtaccg
     1321 tggtggtcgt tttgattttg agagagaagg gtgatggagt tggaagttaa aacaaatgtt
     1381 aattctctgg aaatagagtt ctattcaatt ttacaaaaaa aactggaaga ttacacggaa
     1441 aaattgcttg cagtcagtca tttacctctg gtattaacaa atactgattt aaagcgacta
     1501 tttcagataa gtgatagtac actgaaccgt ttagtaaaac ttggtgagtt tcctccctgt
     1561 tggtacggga ttcgaggaca ctattttcgt gatgatgttt tagaatggat gagaaagagt
     1621 gattcgaatg actatcgaga aaaattgcga ctacttcgat ctttataagt tacattttct
     1681 ttctaagatg cggtacaatg atgacataga tagaaagatt tccaaagggt ttctgcttgt
     1741 tgggttcctt caaaatagga ggaatcaata aatggaaaaa acagatcgat tcaagaagca
     1801 aatcagttct actggtagga tcacatggta ctttcaagca tatcgaacaa caagacgtgg
     1861 ctttaattca aaacgtgagg cgcaactcgc ttatctggaa atggagaaac aacaaaggct
     1921 taagaaaaaa attgttgcaa gcaatgacaa gtttagtgtt gtaggtgagc aatggttcca
     1981 atattaccgt tcgttaaatg aacaaaagga aataacctat gataagcgag aggaacaatt
     2041 aaaaattatt gttcgatgga ttggtgataa aaagttgtct gatttgacac cagagtgcct
     2101 tcaagaattg ctttttacct taaaggaatg tggcgttaat ggaacaaatg ttggctatgc
     2161 caaaaatagt ttacaatcac ttattcaagt tctaaatatg atttttaaat attgtcaaag
     2221 aaagaatttg ataagtgaaa atccaatgaa gtctgtgaga atgccaaaat atcagttaac
     2281 ggtaactgat ttaaaagaag ccataaataa tattgaggac aagtttctta ctgtcgatga
     2341 attgagaact tttttgaatt atggcattgt tcatgaggaa ttaccgatgt ctgtactttt
     2401 ccatgttcta ttttacactg gctgccgagt cagcgaggcg cttgctctac agcctggaga
     2461 tatagatttc aaaagaaatg aaattctgtt ctataagcaa acggcagtta aaggtaagag
     2521 taaggatttt cgaattgaaa ctactaagac agttagttct gctagacgag ttctagtaac
     2581 tcctctagtt atggaaaagc tacaacagtt gattaaggct ttgggtgaga tgaggcaaca
     2641 ttacaggttt attatagaag aaacatattt gtttgtgtat cttgattcta gtaaacgtgg
     2701 tgttccttat cgtcgagagt atgtaaatga tcacgtcaaa cggtgcgtga atcgctcagg
     2761 aattaataag ccatttcata ctcatttagc tcgtcataca atggcaagct tagtagcgga
     2821 acactgtagc tgggaagtct tgaaagatcg cttaggccat actgaccaaa caacttcgaa
     2881 aatttatcgc cacttaacgt caaatgaaaa ggtaaaacct ctgattgctt ttagttcttt
     2941 agagagttaa aaaaacggtg aaagcactgg tattacagga ttcttgaaaa acgatttttt
     3001 aacaaattag tcaatatgta gtcagaggta ataaaaatcc ttttatatca atactttaac
     3061 gacttttcac aagtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa
     3121 cccttggtat tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt
     3181 tttctttaat tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta
     3241 gtaaaaaaaa gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc
     3301 cagaatattc taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta
     3361 tacttatacg gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt
     3421 aaaacaagta ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg
     3481 ctttgaccat ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt
     3541 ttctagtggc gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag
     3601 aagttcagac ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat
     3661 actcattgaa aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt
     3721 ttgtcatctg tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga
     3781 taaaagctaa tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag
     3841 cgtacatgaa aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt
     3901 acgaataaat accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa
     3961 gataacaaga tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa
     4021 acagtatttt gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac
     4081 cattttttaa gtgaatacaa gatcagctaa ttgaacaccg tttattcgtg atgagggaca
     4141 caacactgca gtcgacacat ttctctttta tgttcaaaga taacaaatat ttaaaacaaa
     4201 gaaaaatag
//
LOCUS       DADVXV010000149         4068 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.155, whole genome shotgun sequence.
ACCESSION   DADVXV010000149 DADVXV010000000
VERSION     DADVXV010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.155"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            87..1436
                     /locus_tag="KB969_002807"
     CDS             87..1436
                     /locus_tag="KB969_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6870715.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1564..2154)
                     /locus_tag="KB969_002808"
     CDS             complement(1564..2154)
                     /locus_tag="KB969_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBB6870716.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2301..3653
                     /gene="brnQ"
                     /locus_tag="KB969_002809"
     CDS             2301..3653
                     /gene="brnQ"
                     /locus_tag="KB969_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBB6870717.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1173 a          744 c          790 g         1361 t
ORIGIN      
        1 gaaaattttg gaatcttagt tgtgtttttc agaaaactct cttaatatgg aagtaattaa
       61 acttttttag ttaggatgat ttaaaaatga atgaagagca agaactgcag cgtggactga
      121 aaaatagaca tgtccaactg atttctattg gcggagcgat tggaacgggg ttgtttttag
      181 gttccggaaa gtctatccag ctagctggcc cttcgatatt gctcgcctat cttattactg
      241 gatgcatctg ttttttcatt atgcgtgcgt taggcgaact tctgttatca aacaccaata
      301 accattcttt tctggatttt gttgcagaat atcttggcaa aaaagcggct ttcatcactg
      361 gctggacgta ttggttctgc tgggtatcga ttgcaatggc cgatttaaca gccatcggaa
      421 tgtatgtacg ctactgggcg cctggtgttc ctcagtggct tcctgaactg attgcattag
      481 gtcttcttct ttgcttgaat atggtggctg tctcattgtt tggtgagtta gagttttggt
      541 ttgcattgat caaagttgta gcgatcattg cctttatcct cgtaggagct tatatgatcc
      601 tcacccacta tacgacagat attggcacag ccagtatcac gaatctatgg tctcatggcg
      661 gattctttcc aactggtgca aaaggattta tcttagcttt ccaaatggta acctttgctt
      721 ttgctgggat agaattagtt ggattagtcg ctggagaaac agaaaatcct gaaaaagtgt
      781 tgccggaagc tatcaataat attcctatca ggatcatctt attttactta ggatctcttt
      841 ttgtcattat ggcaatctat ccatggaaca gcttgaatcc agataacagt ccatttgtag
      901 aagtattttc ggaaattggg atcacgattg ctgcttcctt gatcaattta gtcgtattaa
      961 gtgcagcagc ttctgcctgc aacagtgcaa tatatagtac aggacgtatg cttcgttctt
     1021 tagcgcaaga aggcagtgcc cctaaaaaat tcaaaaagtt aacaacacat catgtgccag
     1081 ggaatgcttt gacattttct actatcgtca ttttcatttc tgttatcttg aattacgtga
     1141 tgcctagtga agtattcaca ctagtaagca gtattgccac tacttgtttc ttgtttatct
     1201 ggagtatgct tgtctacacg cacatgaaat atcgtaaaag tatcctcggc aaaaaagctc
     1261 attcatttaa aatgccgttg tacccattta gtaattatct ggtatttctt tacatggcct
     1321 ttgtgtgtgt cgtcttgttc ctaggaaaag atacgagaat cgctttatta ctaacacctg
     1381 tgtggttctt gcttctatta ctaatctatc atatgaaata tgaacgtaag aagtaagaaa
     1441 gtagttgtga cagaagtggt cagcttcgag aaataagaag gaatttacga aaattgcttc
     1501 ttaaattttt gtgaaatttc ggcttatttc ttggagataa aagcttctgt cccagcctct
     1561 tttctatttc cccggaaaca accgctgata ataggcatct gcttttttat aggaaaaaat
     1621 ccaaatacca gatacaaaaa aacgtccgaa taacccgatc aacggtacaa aaaagacacc
     1681 ggcaatcaag cataagttaa tcatcatgga gataagactt cgacggtcct ttgacaaaac
     1741 tctcacgaca tgggaatctg gtttatttgc tttcatgatt tgcctcatca agataccaaa
     1801 agaaaaactc cacatcgtgt atactaagac ataagccatc tcaggccaaa aagcttcagg
     1861 gttacgcccg acccaactag taacagaagg acataaagtc agccaaaaga gcaaaaagat
     1921 attcgaccag accactcggt aattaattcg ttctgccatc tgaaatatac gatgatggtt
     1981 cacccagatc accgcaacaa atataaagct gatggtataa gctaataatg tatttcggat
     2041 gacccataaa gaatgaaagc tagatgtatt agggatcttg atctctaata caagaactct
     2101 caaaacaatg gctaccactc catcagtaaa tgcttctaat ctcgactttg tcacgatgat
     2161 tcctcctcag atgattcagc gcttttattt tatcacttac gttattaaat aaccatcgtt
     2221 ttatataggg aattttctga aaattgttgc atatttttcg aaattttgtt acttttaaaa
     2281 aaaccgtaaa ggagttatgt atgacaaaaa aattatcatt taaagactat ctttttatag
     2341 gctccatgct tttcggtcta ttttttggtg ctggaaatct tatctttccc gttcatttgg
     2401 gtcaagaagc aggcgctgct accttttggg cgaatctagg tttcttggtt accggtatcg
     2461 gtcttccctt cttaggggtg attgccattg gtgtatcgaa aagctcaggt gtatatgaat
     2521 tagcaaaacg gataaatcaa acatatgcga tggtttttac catcttgctt tacttagtta
     2581 tcggaccgtt ttttgcttta cctcgccttg caaccacatc tttcgagatt ggtttagcac
     2641 catttatcga tcctagcaga cagacgctat atctagcaat tttcagtatt gtattttttg
     2701 tgctggcttg gtggttttca agaaaaccga caaagatatt agattatgtt ggaaagttcc
     2761 tgaatcctgc atttttggtt ttattaggtg ctttgcttct ccttgctttt ttgaatccac
     2821 taggttctgt aaatcaagcg cctattcagc caaattatca agagcatgct tttttcacag
     2881 ggtttactca aggatataac acattagatg cgcttgctgc tttagcattt gggatcatca
     2941 ttgtcacaac aatccaaaac atgggtgtaa caaaacctgc tgaaatcgct aaagacacga
     3001 tcaaatctgg tgcgatcagc attatattga tgggaatcat ttatactttg ctcgcttatt
     3061 taggtgctat gagcttaggt agctttgctc taagtgaaaa tggcgggatc acgctggctc
     3121 agattgctga tcattattta ggtacttatg gcagtatctt attagcattt atcgttatat
     3181 tagcttgctt gaagaccggt attggtttga ttacagcttt tgcagaaaca ttcacagatt
     3241 tgtttccgca aagaaattac gcattctttg ttgcacttgc tagtatcctt ccttgtttag
     3301 cggcaaacgt aggcttgacg aatatcattc aattttcgtt gcctgttttg atgttcatct
     3361 atccattagc aatgacactg attttactag tgttagttgg tcctttgttt aagcagcgta
     3421 cggctgttta tcgaatgact acttatttta cattgattgc ttcgattttt gatgggttga
     3481 acgcttgccc agaaactatc aaacaaacac ctattgttca aaatctttta tatgttgcgg
     3541 aaagctactt gccgtttttc aaattgggga tggggtggat cgtaccagca gttatcggtt
     3601 ttgttatcgg actgatttgg agtttcgcta agaaagaaga agtagcagat tgataaaaga
     3661 ggttgtgaaa gagacgttca gccttgagca ataaaaagta attttgaaaa atggcttctc
     3721 acatttttgc ataaatttga cttaataccg agaaactgac ttttgaacac cgtttattga
     3781 gaggtcgtga aaaagccgct tagtttcaag tattaagaaa tattttgtga aaatggcttc
     3841 tcacattttt gcataaattt gacttaatac cgagaaactg gcttttgaac accgtttatt
     3901 gagcgtctat aaactgacct gagtattaga gaaacaaaac ggcaaagtag ctccatatac
     3961 tttgccgttt tgttttgaac taataccgaa gagaagctga tcaaacaaca tttcttttat
     4021 aatatagatt ttagacatat atatgatata aaaatagttt tcgcaaaa
//
LOCUS       DADVXV010000150         4001 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.157, whole genome shotgun sequence.
ACCESSION   DADVXV010000150 DADVXV010000000
VERSION     DADVXV010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.157"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..928)
                     /locus_tag="KB969_002810"
     CDS             complement(<1..928)
                     /locus_tag="KB969_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6870718.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASV"
     gene            complement(1048..1695)
                     /locus_tag="KB969_002811"
     CDS             complement(1048..1695)
                     /locus_tag="KB969_002811"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBB6870719.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(1779..3206)
                     /gene="uxaC"
                     /locus_tag="KB969_002812"
     CDS             complement(1779..3206)
                     /gene="uxaC"
                     /locus_tag="KB969_002812"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBB6870720.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(3280..>4001)
                     /gene="uxuA"
                     /locus_tag="KB969_002813"
     CDS             complement(3280..>4001)
                     /gene="uxuA"
                     /locus_tag="KB969_002813"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6870721.1"
                     /translation="LDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEPHRLS
                     QIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLPRIVK
                     NRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRNIKYL
                     SDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGYGLYD
                     RALGAVYLNGIWEALEKGASK"
BASE COUNT         1294 a          824 c          541 g         1342 t
ORIGIN      
        1 ctactgatgc cagttctttt tttccatatt ttttacttaa aaacaaagtt aaaggcgaaa
       61 caactattaa aaccaaaata ggattgataa aattcattaa aactattccc tgtgcatcat
      121 tatagtaatc aggaaataca taattattca tactcataat taataattga gcaaggagta
      181 agaaaatagc cgcaccaatt atagaaagta atgccctatt tttaactaac ccttttaaag
      241 attttaacaa tgaaactttg tattgagatt ggtcaattct tactcgttca gtagttagtt
      301 tataacatat taaataacaa ataagtgcac atatcgaaaa tattcccgca acaattgtaa
      361 aagttgatcc accacgaact atttgagcgc ctgaatcatc tcttgtataa ataaataatg
      421 gtgttaatac accaatgacc aaacttgcta aagtagctcc aacatttcgg aatgtcgata
      481 gcattgttct ttcttctgta atagaagtaa tagctgatgc cattgatcca taaggaatat
      541 ttatagatgt gtaaaaaata ctcccccata atatatacgt aacatacatg tatactacct
      601 taacgctcat agaagctgaa atcatagaag tttgatacat taaaaaactt gctaaagcga
      661 ctggaccact cattcttaaa atccacggtt taaacttacc ctgcttagtt gctttcgatc
      721 tatcaacaat acgccccata gttacatcag taactgcatc gataaatctt gctactaaaa
      781 ataatgttcc aacggcagct ccgcttatcc ccaatacttt tgtataaaag atcattaaaa
      841 aagaactagc aaaaatgaaa gtaaaatcgt ttccaaaatc tccaaacata tatcctattt
      901 tgtctcttat accaaatttt ctttccatac aattctctcc cttctgttgt taagcgtttt
      961 cattctgatg aaagtacgta ctatactctg aagcgtaaag agtcagtatt tattttttac
     1021 atttcagagt attatttgtt ttttctccta ataattcttt atctcataaa acttatctat
     1081 atatttacta gctactcgac ttacttcttc aaaatcacct ttttcaacag aagccaataa
     1141 attcccacct acaccaactg caacaactcc tacttcaaac caatcttcta agttctctat
     1201 acttactccg ccagtaggca ttatatttac gtgtggtaat ggagcttgat aggcttttac
     1261 aatggatgga ccaaaagcag aacctgggaa tagtttaatg atatctacgc cagcagtaag
     1321 tgcctccttt atctcagtaa ttgtcataca acctggtaaa taaggaattt gatataaatt
     1381 acaaatctca gctgtttgtc gatcaaaaga tggactaacg atatattctg ccccagccat
     1441 aattgcgata cgagcagtaa acgcatctaa aaccgtaccg gctccgatta ttacatcttt
     1501 ttgatcagca tattttttag caatttcttt gattatttct tcagcattag gaactgtaaa
     1561 agttagttca atccctttaa ttccacccgc aataattgaa tttattgctt taatggcctc
     1621 atccttattt ttcccacgta caaccgcaat gactccagcc gcttctaact tacttaaaat
     1681 ttctactttt ttcatatcta tctccttcct ttatggatac atactttgtc tagctgtact
     1741 aacttacaaa gaataaattt aagcttttat ttcaagtatt attttctact tccgatttca
     1801 aaaaaattaa aataattata cgcattacga taacaaatat tctccactat ctgactaaga
     1861 tacatttcat catctggaat tcggcctgct ttaacccact cgcttagtaa ttgacataat
     1921 actcgacgaa aatactcatg gcgaggatag cttagaaaac ttcgagaatc agtcaacata
     1981 cctgtaaaat tcgacaacaa actttgttgt gccatcgtag tcaactgttg acgcattcct
     2041 tcagctgtat cattgaacca ccaagcacat cccaattgga ttttttgaat cataccccct
     2101 tggaagcttt gcattgctgt tgctagtgga agccaatcag ttggatttaa tgaatataaa
     2161 attgtttttg gtaagcaccc actcttttca gcggtatcga acaatgctac aacattttgt
     2221 gtcaaactag cttgatcccc catcgaatca ccaccgacat ctactccaat ttgttccttt
     2281 aatatacttg aattatttct taaagcattt aaatgcattt gcatcgtcca accatatctt
     2341 gtatactcag acatcaaatg taattgaata cctgtaacaa attgtgcaat ttctgataaa
     2401 tggaaatccg tttttcctgc taaagctttt attaacagat tgtcgagtat tttttcatct
     2461 gctatttcat aaaaataagt attcaaaccg tgatctgcta atcgacagcc aatttgatga
     2521 aaatgatcca ctcgttggct caatgcttgc ttcaacccat taaagtcttt gattggtata
     2581 gccgctgttt gactaagttt taaaatatag ttcgaaaagc ctgatgattt gatactccag
     2641 accttatctg gacggaaagt aggtaatacc ttgaaagaat tatcctgttt agaaagctca
     2701 gtatgatacc acaagtcatc tgtaggatca tccgttgtac agatggcttt cacatccatc
     2761 atctccaaca attctttcgg gcgataggaa tccgtttgaa ttttttcgtt agcacgtcgc
     2821 caaatttctg gtgcattctt ctcagaaatt gtcaaatcaa tatcaaagta acgttgtaat
     2881 tccaaatgag accattcaaa aataggatta cctggcgcct tctccactgt ttttacaaaa
     2941 gctaaaaatt tttcataatc atcacctgga ccactgatca actcttcttc tataccatta
     3001 gctcgcatca atcgccattt ataatgatct ccagctcctt tatcatttaa ccatacctga
     3061 gtcaaattct tgtattgctt attttctagc aaatatgctg ggtctaaatg acaatgatag
     3121 tcgataattg gttggtgttt tgcaaattta tgaaaaagtc ttttagctat ttcattctct
     3181 aataaaaagt tcttatctaa aaacatattt aaacactcct ttccttccgt tagtttttag
     3241 aagagaaaat ttttcctcta aataaactcc cttatataat tatttactcg cccccttttc
     3301 aagcgcttcc caaataccat ttaaataaac tgcacctaga gctcggtcat ataatccata
     3361 accaggtcta ccggtttctc cccaaatcat ccgaccatga tctggacgaa tatagccatt
     3421 aaatccatta tcgtacattg tttttaatat cttatacata tctagagaac catattctga
     3481 tttatgcggc gcttcgtaaa aatcgagtcc attgtcactt aaatatttga tattacgaac
     3541 atgtgcaaaa ggaatccgat cccgttgaca aaattcagat agaatttcat agacatcatt
     3601 atctggtcgt tctgcaatac ttccagtaca taatgtaata ccattagaag gagaatccac
     3661 tacattacac aaccaatcta aatcgtcacg atttttaaca atacgaggta atccgaaaat
     3721 ggaatatggt ggatcatctg ggtgaactgc cattttaatc ccaacttctt cacatgtcgg
     3781 gataattgct ttgagaaaat atgcaaagtt ctctcgtaat ttctcttcat caacttcttt
     3841 ataggcttct aataattgct taatttgtga taaccgatga ggttcccaac ccggcaattc
     3901 aaaattatta gtagaatttt ctacttctct aataatttcc tccggatcag tagggatatt
     3961 ttttgaaata taggctaacg tagaagaccc atcatctaaa c
//
LOCUS       DADVXV010000151         3992 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.158, whole genome shotgun sequence.
ACCESSION   DADVXV010000151 DADVXV010000000
VERSION     DADVXV010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.158"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            526..2019
                     /locus_tag="KB969_002814"
     CDS             526..2019
                     /locus_tag="KB969_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBB6870722.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            2154..2450
                     /locus_tag="KB969_002815"
     CDS             2154..2450
                     /locus_tag="KB969_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBB6870723.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            2551..3402
                     /locus_tag="KB969_002816"
     CDS             2551..3402
                     /locus_tag="KB969_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870724.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            3423..3706
                     /locus_tag="KB969_002817"
                     /pseudo
     CDS             3423..3706
                     /locus_tag="KB969_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1418 a          577 c          806 g         1191 t
ORIGIN      
        1 taagaattca gactttataa ggaatatagt ggatatacta aatatatttg ctatattcag
       61 tatatcagat atattcaaaa tgtcaaaata tatttgtgcg ttttgcgttg acaatttaga
      121 gtgaaaagag gtaaacttaa ttctatagaa accacagata attcactatt tacaaagtag
      181 caaaagcagt ggtactcttt aaacagaaaa attacataaa aaaaagagac ggaaataatt
      241 gattttagca gaatcaatta tttctgaatc acatggttag gacatgtgtt cacgctcgtc
      301 tcaagaatat gtaagtagct accaactact tatattaaaa gttgatcgga taccttttcc
      361 gattgccttt attctaccaa aaaaaggcga gcaactcaac agaagaacgt ttatttagtg
      421 tacttaaatt aaatattctt aaacactgaa gagagaacac atactatggc tgagattaaa
      481 gctaaactgt gttctctttt tgtttgagaa aggacgttac aatcgatgtt gagcgaaatt
      541 tattcagcta ttcttaaaaa cggcttacgt acatacaaat atcgaaacag caccatgaaa
      601 cctgcaggtc atattgattc cagtaggagt ggtgctatct ttgcgtaccg tagcaagcaa
      661 ttaatgaatg ttgggcgtgg tatggtcatt acttcggaag aagctatttt agagaacgaa
      721 aagaaactaa cgcattggac acctaatacc tatcgctttg gtacttatgc ggatgattat
      781 cgaacagtgg ttaaaggtca ttctgagaaa aacttaagtc aaatcaacac atttgtagtt
      841 gatatcgatt caaaagagaa ccatcaaggc gaaattattt tagcctgttt agatcaagtg
      901 ggctacatgc caacgctaat tttagaatca gatcatggtt atcaagttta ttttgtacta
      961 aagacaccag gctatgtcac aaagaaaagc aatttcaagg tgatcgatgt agcaaaaaaa
     1021 atttcaaaaa caattcgtct acagttggct gaaaaattgt ccggagtgga tctaggatgt
     1081 aaccacttcg gaattgctcg attcccacaa gaaaataata ttgtttttaa agaaatgaac
     1141 tatcagtatt cttttgctga ctggattcaa tggtcgatga agcttgaatc agatcaaaaa
     1201 acaaaagaag atcgagaacg aaaactaatt gtctttcctg agaaaaaaga aattcgtcaa
     1261 gtagatgaac cgtggttcga tatgttactt cataaagcaa acatcgtcgg cggagaagga
     1321 cgtcttggtc gaaataatgt gattttcacg ctttctttag cttattactc ttcaggttat
     1381 gcattggata cttgcgaata caatatgttc acattcaacg aacggttaca ggaaccgcta
     1441 tctgaagcag aattagtaaa gattgtacgt agtgcttatt ctggtaatta tcaagcagca
     1501 agcagagaat tcattattga attgtgccag caatgggttt caccaacctt aaaaaataat
     1561 gatctgttca ttcaacgacg tggctggtgg aaatttaaaa agccacgaga tcaaagaaaa
     1621 tatagtcata aaaatgaatg gaaagaagat ctattggctt atctaagcga aaaaagtctt
     1681 gctagtgagc cttatttgaa cctgtcaaaa aaagaattgg cttcacaact aacgatgccc
     1741 aagcgaacac ttgataagat cttaaatgag ttacgagagg agaataaagt cttctacaag
     1801 gtaacacgag gaagaaatgg cggaatgatc attgcttcag tcaaaacgtt gttcgcgagg
     1861 gttattcaac taagtaaaga aaagagacta gattattcaa caaggatcac agaggtattt
     1921 ggactcaacg agagcttagt agaagagaca tttagacaat tatcaacccc cttgaaccct
     1981 cttaaagaag tgaatctttt tgaagtagat acaggttgaa aaataaaagg tgcaaattgc
     2041 cttatacaat atatctatga tacttctgta ggtgttgctc cctttgccta gctacgtgta
     2101 ggtggtatac ttataactgc gtatgcagtc ttatgtatca tggaggaagt tgtatgtcgt
     2161 taaaaaatta tgtctattca catcctgtta atgtgtttat cattggtcgt ttgggattat
     2221 ctgtggaagt gttctgtgag ctttatggtt ttaagcaggg gactttgtct tcttgggtta
     2281 ccagggaaaa aacagttgct tctttgccga ttgagtttct tcatgggttg tccttagctt
     2341 ctggggagac tatggatcag gtatatgatt gtttgtgtgt gttagagcag gagtatattg
     2401 agtataaaat agctaacgag ttaagaaaaa ggaagaagta tatccagtag tagtttttat
     2461 ttacttaaaa aattggttca ttgagcaacc tatcgctgct aaagtagcaa aggaaaacgt
     2521 taaaggaaag aatttaggga agaaatcgaa atgaaatcgg acgactggat tgaacacacc
     2581 tggcttcctc tgaaaagaaa tagcaaacga aagaaatttt gggtattgca attatggcca
     2641 ttaggaaaac tttgtagtta cggggcacga cttattcttg atttaaccgt ttactcgatt
     2701 ggagtatttg gaacggctta ttacttgata aatgatccca ataggattgc agcatcagac
     2761 atttttacag tgctaatgac gttgattttt gtcatgctat tgtctatttt tactcaatta
     2821 gtcatgcaat ttaccaggca aaaattaaca gcaggaaaac ttttcaaaag cctattcgat
     2881 ttaattgttg taaatgcaat tctagcgact ttaataaaac aaattgaaca atctggaaga
     2941 acaacaaaag gagtgaagga ttttttattg acgtttattc actttgtaaa tggacacatg
     3001 tatttgtttg aagtgggtat tattctcttt tttgtcgggt atgtatccac gaaacttatt
     3061 aaacgttcaa ttgaaaaaga aattgaaatt gacctgattc cgacacttct tggttatgag
     3121 tacaatgttg attttggaag atatgacgaa ttgatcaata cggatatcgt tcacacgagt
     3181 atccatgaat ctactgttaa gggcatcaga tctattttaa aaaatggcca ggaaatgaaa
     3241 gcaatagatc gaagaaaaga gatctacaat ttttatgaag tcgaagcaag cctacgatat
     3301 ggcatcggaa aattgtggtt agatggaagt aatattcgtc aaaacaaacc atacattttt
     3361 tggaacagta gtgatttaga acttccaatg aaagataaat aattatggag aatcgtttga
     3421 aaatgattcc tctatacagg attgtgctta tagttggcat ggagttaaaa accttaaaga
     3481 aggagcagtt attcaaagtg aaagaacgtc ataatcagtt actatgtagt aaaacgggta
     3541 cgatgaacat tgaataccga acagaatatt tagaattaac gaatcaaact gattttttgt
     3601 tgattcgaaa gcaacaagag caagaaaaaa attaatggct acttatagcc aattgattga
     3661 tgaatgggaa caattcaagg aatctaaaat tccagaacgt ctctaaaagc ctttatttgt
     3721 aaagagcata aggaaacgtg ggaacacttt ttaaaaaaag tgttccaata ggctgtgcct
     3781 attacgtttc tcaaaaataa atgtgggaac aaaatattta aaaataggat agtgaaagga
     3841 tagtgaagga tagtaaaagg agggtagtag gatagcaaaa aggataggct ccttttcgct
     3901 atccttttta aattggagga attaatatgg aagtaagaat aagaaatgtg gatgagaaaa
     3961 tcgtaagaga aattgatcga agatgtgacg aa
//
LOCUS       DADVXV010000152         3904 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.159, whole genome shotgun sequence.
ACCESSION   DADVXV010000152 DADVXV010000000
VERSION     DADVXV010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.159"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..702
                     /locus_tag="KB969_002818"
     CDS             <1..702
                     /locus_tag="KB969_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase family protein"
                     /protein_id="HBB6870725.1"
                     /translation="DEESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTG
                     MADIHEVSEAVDCFIDSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSL
                     GYDVGICAVAMGAKVIEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGV
                     KRAMPSELSTKEVSRKSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVK
                     RPISADSVLLEEDVE"
     gene            699..1847
                     /gene="neuC"
                     /locus_tag="KB969_002819"
     CDS             699..1847
                     /gene="neuC"
                     /locus_tag="KB969_002819"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBB6870726.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            1820..2497
                     /locus_tag="KB969_002820"
     CDS             1820..2497
                     /locus_tag="KB969_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBB6870727.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            2487..3629
                     /locus_tag="KB969_002821"
     CDS             2487..3629
                     /locus_tag="KB969_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBB6870728.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            3642..>3904
                     /locus_tag="KB969_002822"
     CDS             3642..>3904
                     /locus_tag="KB969_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6870729.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCN"
BASE COUNT         1416 a          508 c          785 g         1195 t
ORIGIN      
        1 gatgaagaaa gtgcagactt tctaaaacaa attggtgtac aaggatttaa aattggctca
       61 ggagatttaa caaatttacc ttttcttaga aaaatagata tgtatgggtt gccagtttta
      121 ttatctacag gtatggctga tattcatgag gtcagtgagg ctgtagattg tttcatagat
      181 agtccagtta ctattttaca ttgtacttca aattatccgg ctagttctga agatattaat
      241 ttattggcga ttaacacatt aaaagaaatg ttcgggatac ccgttgggta ctccgatcat
      301 tcattgggat atgatgttgg tatttgtgct gttgcgatgg gtgctaaggt aattgagaaa
      361 cattttacct tggataagga actacctggt ccagatcata aagcttcttt agatcctcag
      421 gaatttgcag attttgtaaa gcatattaga aacactgaaa tatttttagg tgatggtgtt
      481 aagcgagcaa tgccttctga acttagtaca aaagaagtat caagaaaaag cctagtggtc
      541 actgagaatt taaatgtggg agatattctt acagagaaat ctcttacaat aaaacgtcct
      601 ggaaatggaa tagctcctaa gtttttatat caatatattg gcaaaaaagt taaaagacca
      661 ataagtgcag atagtgttct gcttgaggaa gatgttgaat gaaaaaaata cttatagtaa
      721 gtggaacacg agctgattat ggaatatata aacctgttgc tgagaattta ctacaagata
      781 attgggatgt atcatttgtt gtttctggaa tgcatttatc ccataaatat ggatttacta
      841 aagaattgat cttagctgac ggatttagaa ttagtggaga agttcaaagt ttgtttttag
      901 agaacaataa gggaaacatg gctcggtctg tggcattaga gataaatggt ttcacaaata
      961 tatttgaaca aactagccct gattttgtat tattactagg ggatagagga gaaatgttgg
     1021 cagctgcgat agcttgtttg tatcttggaa tcaaaacagc acatattcac ggaggcgaag
     1081 tgtctggtac tgtagatgaa tcaataagac atgccataac gaaaatagca tctgttcatt
     1141 ttgctgctac ggaaaaaagc aaagagcgtt taataaaaat gggggaagat tcttggagag
     1201 tttttcccgt cggagctcct agaatagata ctattttaaa taatagatta cctagtttta
     1261 gagatataaa agaaaaatat catctaaaat ttgaaaagaa aaaatacgtt ttgcaagtat
     1321 ttcatccagt tgtaaccgaa ctagaaaata tagaaaaaca aattttagct ttgatcaatt
     1381 caatggaaca acaatctcaa ccaattattt gcattttacc taatagtgat gctggtagcg
     1441 aaattatcag aaaaatgtac cagaaatatt taaaaacgga tattatttat attacgaatt
     1501 tagagccgga ggaatacctg actatattaa aagagtgcaa atttatgatc ggaaattctt
     1561 cttctgggat aattgaagct gcatcattca aaataccagt aataaattta ggaaccagac
     1621 aaaatggacg agaacaatct aaaaatatta taaatgcaaa tctaaatgaa aatgaaattg
     1681 aaactgcttt gaataaaata caagatcctc agtttataaa aagcttgaaa aatgttaaga
     1741 acatctacgg tgacggcaac agttctagaa gaataacaaa aacattgaat caaatattga
     1801 atgatgggga agatattaag tggattcaaa aacaaatagc ttattaaaat atactagtga
     1861 tccatacatt attattgggg ctggcggaca cgcaaaagtc attattgaaa ccttaagatt
     1921 agaaaataag ttaatatatg gattttttga tgataagcaa aataaaatgc aagatctgaa
     1981 atatcttggg aaaataaacg aattgaatag ctgggcggat agcaaaaaaa aaatctataa
     2041 atttattgta gctattggtg actgtgtagt aagaaaaaag attataaaaa aattgaatat
     2101 gccaagtgag caatatggaa tagctgttca tccaagtgct atagtggcaa aagaaatttc
     2161 aattggttat ggaactgtta tttttgcgaa tgctgtaatt aacccagatg ctgtaattgg
     2221 agagcatgct ataataaaca caggtagcat tgttgagcat gattgtagaa ttaataacta
     2281 tgttcattta tctccaggtg tatgcttagc gggtggagta catgtaggtg taggaactca
     2341 aataggaatt ggttctcaat gtatccagat gaagaaaatt ggatcttggt gtatgatagg
     2401 cgcagggagc actattgtta aggatattcc ctcacattcc ttagcttatg gcaatccagc
     2461 taaaattaag aaagaaggaa ttaattttga attctagaat tttattatca agtcctcata
     2521 tgggaggaac agaagaaaaa tatgttgcta aggcttttaa agataattgg atagcgccat
     2581 taggtgaaaa tgtggataaa tttgaagaaa gtattacaaa atatactggt tctaagggcg
     2641 gagcttctgc gttaagttca ggtacagctg ccatacatct tgccttaaga ctgcttaatg
     2701 ttggaaaaaa cgatattgtc tttgctcctt catttacttt tatagctaca gtaaatccta
     2761 ttttatatca aggggctgta ccagtgttca ttgactcaga acctaataca tggaatatga
     2821 gccctgttgc actagagagc gcattagaag aagctgaaag aaacaaccaa ttacctaagg
     2881 caatcatcgt agtgaattta tatggtcaaa tggctgatta tgaacgaatt ttagctattg
     2941 caaaccaatt taatgttcca gtgatagaag atgcagcgga atcgttaggt tctacttata
     3001 agggaatttc gtcaggctta tttgggacaa ttgggatcta ttcatttaac ggtaataaga
     3061 tcatcacaac ctcaggtgga ggagctctag tgtctagtga taaaaaatat gttgagcatt
     3121 caagattttt agcaacacaa gcaagagatc aagcaccgta ttatcaacat agcgaaatag
     3181 gttataatta ccgtctaagc aatatttctg ccggtatcgg acgtggacaa atggaagtat
     3241 tgaatgatag agtagctaaa cgaagagaaa ttttcaatcg atataaggaa gctttttctg
     3301 gaattgatag aattgaaatg atgccagaag tggatggcat ggtgccaaat cgttggttgt
     3361 ctactttaac gatcaatgat tataattcta ttgatcaagt agttaacgta ataaataaac
     3421 taaatgaaaa aaacattgaa acaagagctt tgtggaaacc actacatttg caaccagtat
     3481 ttcaaggggt aaaaatgtat taccatgata ataatcttag tgtgtcagaa aagttattta
     3541 atagcggctt atgcttacct tctggaagta atatgacaga tagtgaacaa gaatttgtta
     3601 ttgatgagtt taaaaaaata ttcaagtagg tgtgatattt tatgaacata ggaattattg
     3661 gtttaggttc catggggaaa agaagactta gactcattca agaacacttt aatgatattt
     3721 tactatgtgg tgttgatact aatgaggcga gacgaaagga agttgaaaag gaatttggaa
     3781 taccaactta taatagtcta acagaggcaa aaaatttgtt tgaaataaat tcagtttttg
     3841 tttgtacatc ccctataacc catgaattta ttataaaaga ggctttaaat ttagattgta
     3901 atat
//
LOCUS       DADVXV010000153         3872 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.160, whole genome shotgun sequence.
ACCESSION   DADVXV010000153 DADVXV010000000
VERSION     DADVXV010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.160"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(716..3865)
                     /locus_tag="KB969_002823"
     CDS             complement(716..3865)
                     /locus_tag="KB969_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBB6870730.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
BASE COUNT         1076 a          800 c          635 g         1361 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc tt
//
LOCUS       DADVXV010000154         3738 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.161, whole genome shotgun sequence.
ACCESSION   DADVXV010000154 DADVXV010000000
VERSION     DADVXV010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.161"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            72..155
                     /locus_tag="KB969_002824"
     CDS             72..155
                     /locus_tag="KB969_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBB6870731.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            280..1017
                     /gene="erm(B)"
                     /locus_tag="KB969_002825"
     CDS             280..1017
                     /gene="erm(B)"
                     /locus_tag="KB969_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6870732.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1280..2143)
                     /locus_tag="KB969_002826"
     CDS             complement(1280..2143)
                     /locus_tag="KB969_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6870733.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2145..2417)
                     /locus_tag="KB969_002827"
     CDS             complement(2145..2417)
                     /locus_tag="KB969_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6870734.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2434..2643)
                     /locus_tag="KB969_002828"
     CDS             complement(2434..2643)
                     /locus_tag="KB969_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6870735.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(2742..3638)
                     /locus_tag="KB969_002829"
     CDS             complement(2742..3638)
                     /locus_tag="KB969_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6870736.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
BASE COUNT         1148 a          654 c          579 g         1357 t
ORIGIN      
        1 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
       61 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct accgttttga
      121 aacagactaa aaacagtgat tacgcagata aataaatacg ttagattaat tcctaccagt
      181 gactaatctt atgacttttt aaacagataa ctaaaattac aaacaaatcg tttaacttct
      241 gtatttattt atagatgtaa tcacttcagg agtgattaca tgaacaaaaa tataaaatat
      301 tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta
      361 aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg
      421 gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg
      481 tcagaaaaat taaaactgaa cactcgtgtc actttaattc accaagatat tctacagttt
      541 caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca
      601 caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa
      661 gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact
      721 caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaaa
      781 gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg
      841 aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact
      901 aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact
      961 tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc
     1021 tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt
     1081 attaggtata gggcacctct aataactacc aattaattca cctcaaaatg aaattagaaa
     1141 aaaacagcga aatttttaaa tctatttctt atcgatacaa attcctcgta ggcgctcggg
     1201 accccaacat gaggaaatgt ttttataaaa aaagagtagt taccgttttt tggtaactac
     1261 tcttttcctt ttttaaggtt taaatacctg gaagtttagg tgttttgggt attggtggtg
     1321 taggtagctg caagctttcc attttttgtt gaattgcttt aaattcaggg gtttcttggt
     1381 gttgattttg aaccattttt tgctctattc tctccaaagt cggttgaatt tctttccctg
     1441 atactttacg atttaattct ctttctaagg tctctttcgg actaatggaa ggcgtttcta
     1501 agcttgaata gagtttcact ccttctctat tgtaaagcct tatatcgcta aataagcccg
     1561 ttttatgaag ggtttctaaa ttggtcggta agtttttgac aacaatatca tgcgcttgtt
     1621 ttggtgttgc cctagctgtc attggatcat ctgcatacat ggtttcatat cgttcaatcg
     1681 ttcctaagta tgattcaatt ttcggtactg ccatgacgta tatttttgtt tcataacctt
     1741 tagattgaag cattgtggct gtttgaatgg gaacgtctgt tgttcgtcct gttccttcaa
     1801 tcactaaatt atagccttga tcgcttaaac ggctaataag tgcttctgtc atgcgattcg
     1861 aataaggggt aacgtgtttt actacgtctt tttcatagag tttcactaat tcgtcaaaat
     1921 ttgggtgctg ttgtttaaag gtatcattat caatgacaat aacattccct tgtgtttctt
     1981 caaaaattgc tgatcgcaaa ctggttttcc ctgaccctgg ttgcccacca agtaaaaaag
     2041 cggttggcga ttcaaccgct agtctatttt tagttagtcg ttcaacattc ttttctaaac
     2101 gatcttcaaa ttgcttttcg gtgaagtcag taatattcgc catgttaagc cactttctct
     2161 ttattcaaaa tttgttttga atattgattc attgaccgcc aatactcatg aatagcttgt
     2221 aattcttcaa atggttgttg aaataaatca acttcttgtg ccacttctaa ttgatttaaa
     2281 agattcactt ctagtaaacg agtattttta gtatctagtt catgattcaa aacataattt
     2341 aatacccgat tataaacact tgccgataac tcattaatga tttcaatttc aaatgttttt
     2401 tcatacgtaa ctgccatttc attttcactc cttttaaagt ttgtcaggta aatatttccg
     2461 tatatattct tctaaggctt gatccataac ttcttttacg tttccgccat tctttgctgt
     2521 ttcgattttt atgatatggt gcaagtcggc acgaacacga accgtcttat cccccattat
     2581 atcttttttt gcgctgattg gcgtatcatt tcgttttgct ttctgtgcgc ctaaatttcc
     2641 cacgatcgct cacttctttc tatttcttct tactatttat tttatcatca cctatcacaa
     2701 atcacaagtg atttgtgatt aatcacttgt gatttgtgat tctattcttt ttcattttct
     2761 aattgaatga ttcgctcaat catttcaaaa aatacgttct catacataga caaaactttt
     2821 ttgtcatagc ctttgtgttc tgtaatgcca tttttagacc aagtacttac tttattactt
     2881 cgcttgataa tatttcggaa aaccaaatta tcctctttat gttctttgta cagttcttcc
     2941 aggtttgatt ttatcgttgc gctgtccgta tcaactaaat aaggaacaaa accaatcata
     3001 tctagtccag ggttaaactg ttcttgcaaa tcaatcaaat aggaaatata gttttgaatg
     3061 ttgtttgtac tttcttcttc tgcttgtaaa gggatcataa cgtaatcact cgccacgatt
     3121 gcattatttg tataaacgct tggcgttggt acagtatcaa taataataag atcatagtca
     3181 ctttttaaag gtgctaaaag agtagcaagc aatctacttt cattttcaaa cgtccatgag
     3241 cgagttaatt ttggcagtaa catcaaatca aacgtgccag ggatcaagtc taaattatca
     3301 gtcaaatgaa taatagaaga agccaagttt ccatttttca agccttcata aaaattgaca
     3361 cgtggcaatt ctacctcaaa agtttttgct aagtcttttg tcaatgttgc ctgtaagtcc
     3421 ttatcgatca ttaaaacttt taaattcaat ttgtctgtca agtaagcaaa catagtcgat
     3481 aatttggact ttccaacacc acctttaaag taattattca agataataat tgcttcattt
     3541 ttattgttta aaatacgtct taattcttca agtattttta gtttttcctt ctccataact
     3601 acgccccatt ctttttttgt atagtaatat tgtatcatta agaatcacaa atcacaagtg
     3661 atttgtgatt aatcacttgt gatttgtgat aagtgatttg tgattaatat ataaaagccc
     3721 tctttaaagg gcttttat
//
LOCUS       DADVXV010000155         3721 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.162, whole genome shotgun sequence.
ACCESSION   DADVXV010000155 DADVXV010000000
VERSION     DADVXV010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.162"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..356)
                     /locus_tag="KB969_002830"
     CDS             complement(<1..356)
                     /locus_tag="KB969_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870737.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRTF"
     gene            complement(616..1164)
                     /locus_tag="KB969_002831"
     CDS             complement(616..1164)
                     /locus_tag="KB969_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870738.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1165..2022)
                     /locus_tag="KB969_002832"
     CDS             complement(1165..2022)
                     /locus_tag="KB969_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBB6870739.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2308..2594)
                     /locus_tag="KB969_002833"
                     /pseudo
     CDS             complement(2308..2594)
                     /locus_tag="KB969_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2584..2913)
                     /locus_tag="KB969_002834"
     CDS             complement(2584..2913)
                     /locus_tag="KB969_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6870740.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2990..3262)
                     /locus_tag="KB969_002835"
     CDS             complement(2990..3262)
                     /locus_tag="KB969_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBB6870741.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3262..3525)
                     /locus_tag="KB969_002836"
     CDS             complement(3262..3525)
                     /locus_tag="KB969_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBB6870742.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1092 a          754 c          473 g         1402 t
ORIGIN      
        1 ttaaatgttc ttactgcctc ttccacacta atttcttcgt tcaatttcac taataatact
       61 tgatctcgct tattataatc gctttcattt atcctaagag tcaaatcttt ttccaccata
      121 acttttacac ccaataaatt ttgcggttta tttttctctg ttgaaattct ttgtgtagcc
      181 tttaaactga caattagctc attgggtaca tactctattt gagagtcatc taattggctc
      241 ataatccttt ctttttggtt agtatctgca gttacttgtt tagtatgagc catgaaccca
      301 aacatactca ccccaacaac caatcctaaa tatattttct ttttaaactt tttcatctac
      361 atctcctcct aatagtttta ttttagagtt agctctatta cttatttact aactcaacaa
      421 cagattatca tacacttgtt aatgaaatca caatatctca ttaaaacaca ccctaaaatc
      481 ataaccgttc ctatgctcat tttttggatt ttttaatcac gtaaccagaa aaataaatcc
      541 cctctatttc acgcaaatca aagaagaact aagtaactac cgtttaaagg tagttactta
      601 gttcttcttt gattattatc taactttatt attcattccc caccctttgc gcagtgagtc
      661 ttcggtatct tgttttatct gactggtagt tcttattatt tctccacgat catctaattc
      721 tggaacaatt ggatattttt ctctgaacaa gtctagttct ttcaccacgt cattaaacaa
      781 atcttgctta tcttcttgcg taagattctg tttaatatac tcatctaaag cttttctaag
      841 caattcatct cttgtcatat tagtctcata cttttctact aaaactctgg aagtcgcatt
      901 taacaaagtc gacagtttta aaggatgctt ggtggaataa accttatcaa actttctgat
      961 tggtgcgcca actttttttg ttcttcctct actctgtctt tcaacattgg aggaagtttt
     1021 tatttcttga acttggtgca cttctaattg cttattttca gatggtgtaa ttgcttgctg
     1081 ctttttcttt gcttctgctt ctttttttat tttggcgagt cctttgttgt tcccaaaaat
     1141 atcaagtcct ttgatgtcag ccaattactc cacctccgca taccaattct cgtgttcttc
     1201 caattctttc aaaatactga taaataattc gtggcttttg cgatcccatt gttttaagag
     1261 acctttcttt gtcttctcca tcgtaatacc tgatccgtcg tatcgtttta agcgcgcatt
     1321 tttgagtaca acatttttaa tcaaatgttc cccataaatc tcttgggctt gtttatacat
     1381 ttcctgatct actgcgtcac cgctttccaa catgaaagga ataacaccag caacatataa
     1441 atttgtatca aattctttca caaaaaagtc catatactca agatattgca tcgcatttct
     1501 catcgatttt acttgggtct gtaagacgac gattgcccaa tccgcaatgt acatcgcgga
     1561 tttactatat acagaaatag aaggtgggac atctaaatag atgacgtcaa actcatcaaa
     1621 taatggttct agcttttctt tcatatattt gaattgggat aatgaatcat tatattggtc
     1681 tttgatccaa tcatcataca tttcaaagga catgtctgct ggaagtatat agaggttatt
     1741 gattacttta tagacagcct ctttaggtgg aagattgttt atcaacacgt cagtcacagt
     1801 attttcgtaa acaatcggtt caccttctcc gcctccttct tcgttagtga agttcatatg
     1861 cgttaagttc atcacatcag aagtatttcc ttgcatatcc aagtcaatta tcaaggttct
     1921 ttttccttca ttaactgctg attcaaaccc taacatttgc gcgcacgtac ttttacctac
     1981 gccaccttta aaattaccga ttacatattt cttcgctacc acgttcctac ctcttttctt
     2041 ttagcaatat tcatttgata ctattataac atatttattt ttagttacta ccaaaaaaaa
     2101 gatatatatg tactacctta taattaataa gtaaaaggta gtacataaat aaggaaaagc
     2161 tgaaatatat tgatttatag ctttcctcaa agtaatgacg ttatttaatt tatcgagaag
     2221 cagagaatac tcgcgacttt agtcatgtag acgaatcaga ttttcgataa aaaagaagcc
     2281 gtccttctta agaacgacaa caaatcacta gattaatttt ttcaactgtt cataaaagtt
     2341 ttcatgcgtt ccacataaca atactggaat aaccttgttt tctataatct cgtaagctac
     2401 tctatatgtt gtgcccgcat atttgaaccc actagaccaa atacctgata aatccccagt
     2461 tttttgttca cccttatatg gatcaatcgc aatttcatca taaattaaat tcaaaaattt
     2521 ttctttcaat ggcttctctt ttagcttttt aaatacttaa tgacatgttt tgaaggaacg
     2581 atttcataag ccaatttctg ttgccaactc ctctttagtc attactttag aattagtaag
     2641 tgtatcttca gcaatatctc taaaggaaga atgcattttg ttttttctat tcttaaattc
     2701 tacaagaatc tcatctttat cgtagccttc tgcaattata tcagacaaaa tatcttcgct
     2761 aaaatcataa aattcttttt gtggttcaac aaattcataa agaataccat tctctaccaa
     2821 ctttgcttca acttcgactc cattaggaac attaaaatct ttaggtactg tcaacatgat
     2881 tgaattgcct tgttttcttg tttttgtaat catttaaatc cctcatttct aacagtatgt
     2941 aattacttag taaatacatt ataccacgag ataatgtatt tacaagtaat tactgtgact
     3001 cgtaatgcgt ccttgctgaa taaatttcaa ccacgtgttc atcttcatct accttataaa
     3061 caacccggtg ttgtctattc aatcttctag aatacctacc ttcatgtgta ggttttaact
     3121 tctcaaatga ttgggtaggg agatagggat cttcctttaa agtctgaata accttctcaa
     3181 attgaggttt caaattagac tgtttgattt tctttaaatc agctttagcc gagtttttaa
     3241 tcatcacaga atagttattc attataagtt atcccaatca atttcatcaa cattagtaaa
     3301 tccactatca tctttttctc gcttacgaac aacacccaaa gtgcctattt gctcaagtaa
     3361 tagcgtttct ttgattgctt tccaatcatc caaaccaata agcaccgcat tattttcact
     3421 gcgctcacta atgatttcaa tttccgtatg attctcattt acatctttca acaacttata
     3481 aaaatttttc cgtgctgagc taggatttaa gactgttttt gccatatcta ctccccctct
     3541 aatttatatc tccattctaa cgtacttaat taagtacgta aattcgattg ttttgtttaa
     3601 attggagtac caaaacagca ttgtaaagtg ttatccgttt cctttatacc cgtggtgcta
     3661 gttaattttt tcctagagga aaatgtctaa acatgttggt aaatcaacaa aaaaacgcat
     3721 a
//
LOCUS       DADVXV010000156         3629 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.163, whole genome shotgun sequence.
ACCESSION   DADVXV010000156 DADVXV010000000
VERSION     DADVXV010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3629
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.163"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            382..1422
                     /locus_tag="KB969_002837"
     CDS             382..1422
                     /locus_tag="KB969_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBB6870743.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            2246..2578
                     /locus_tag="KB969_002838"
     CDS             2246..2578
                     /locus_tag="KB969_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBB6870744.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            3197..3538
                     /locus_tag="KB969_002839"
     CDS             3197..3538
                     /locus_tag="KB969_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBB6870745.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1342 a          477 c          673 g         1137 t
ORIGIN      
        1 cttgtcttat aagaataata taatatatac tactgaaata aggtagtata tattactagt
       61 aatggtagta tgttttatat gcataaggta gttcttaatt tattttttgt tttgacactg
      121 gtagtactta attatcttta attttaaaac taaattttat tcatacgttt ttctggtagt
      181 atttaattat aaataatatt tatttaaagt agttcttaat gactttaaag gtagtacata
      241 attcatttta tttctgattt taggtagtat ttaattaaaa aacagtttta atgcgtttgc
      301 attttttatt tatctttgct attttcgaaa agagtaggta attttacata aataaaacaa
      361 cgtgaaagta gaggatctac aatgactgat tttaaatttt ttaaggcgga tagagtttac
      421 aacgaattat tttatcaatt tccaaaagtc tttattgttt ctgacgaata caaaaaaatg
      481 aaagattcaa ctaagattgc ctatatgctt ttaaaagcaa gattagagat cgcaatcagc
      541 aaacggcaaa tcgatgaaga aggtaatgtt tattttactt atacgacaaa tgaactatgt
      601 agagtattaa actgccaaaa acaaaaagcg atagcaatca aaaaagagtt ggaatccttt
      661 ggtttattat tacaaaagca gatgggattt aacaaacagt tagggaaaaa taatcctaat
      721 agactatatc tagcagaatt aaaagtctca gaaaatgata tctacttact cgaaaaattt
      781 gatagagaga atagggaaaa cgttgataaa tcagagggta tgaaaatcat acccaccctc
      841 gacgaaaaat cagacgctga atcccttggg gctcaagagg gtatgaaaat cataccgtgc
      901 caaaacgttg ataaatcaga gggtatgaaa atcataccag aacttaataa taatatatta
      961 gacactaata gacacaatat agacactgaa aaagaccgcc tacaagatca attgttgtta
     1021 gacaattttg agacaattat gacaaacgac agcattgcta cgtttgtccc tgaacgagta
     1081 ttaaatttga taaaaacatt ttcttcaagt tacagtgaag ctcaaaaaac cgtccagact
     1141 attcataatg caaagaaaaa agctgaaata gaaagtgata tttcgatagt ttttgaagaa
     1201 ctcgatagtt attatgtcaa tgcagaacaa gaattataca cgacactgtt aaaagcctat
     1261 caaaaattaa aaaccgaaaa agtcgaaaat atccagaacc tgatttttgt ctatgtaaaa
     1321 aattggttta tcgaaaaacc aatagctgct aaagtatcaa gtgaaaaacg tttgaattat
     1381 gcaagctccc caagcactat tacgaaagac tggttagagt gaaactttac tgacaaagtg
     1441 attgttgctt catggagtaa cattaaaatt aaaaattttt tattattcta attatattac
     1501 gaatattaca aaataatagc tattttaata gaatttataa gttaaaatat tatgataaaa
     1561 atcacaaacg tagcctttta cgtcataagt gttaaaagaa ataattaatt tcaaatatag
     1621 aaaagggaac gtatgtttgc atactccttt tttttgagtt ataataatac gcgaagagag
     1681 ataatttcat tatttaaaca agctaaaaat cttgatatta cttcttttca ggcaatacga
     1741 atattattcg cttacatttt ttgtataaat ttaattgtct gctatgcttg tgatgaattg
     1801 attttcgttt tgcacttttg gatgataaat ttggacaatt gaaaatacaa aaaaaagaaa
     1861 ggcggtatga actcggaagg ctggtaacct tcgtcagcgt tcatacacgg cattaagatt
     1921 tggcccttaa tgcgttaacc tttcagtgtt acggtattac ccgcaatgga tttagtataa
     1981 cagatattca aaagtgatac cacttttttt ggctgtgtta aggttaaaaa tacgtgatat
     2041 tacgatgaat ctatgcctaa gcataatgtt ataaaaatgt ccgtgtggct ctttgccgta
     2101 tgacgaacgc tgaaattaga gggaacgcat gtttggatgc gttccctctt ttttgtttgt
     2161 catgaacgaa aatcaattct ctatttttga aaaataacaa gaaaaacttg ttaaaaatat
     2221 ttaaagaaat tgggtggttt attttatgtc atatacagga attttgagtc tcaaagatat
     2281 ttgtcactac ggtaaacggt gtaccgctac agagaaaatc acgaagaaac tatcaactgg
     2341 ccaaagtaaa accgttgtgc agtgtaagaa atatataatc cagaaagaca aagtctcaga
     2401 ggaaatgatt tattacattg ggaaacaaaa gcaaataatt ttaaaagatc ctatcccctt
     2461 aaaagagcta tatccaacaa tcaaacatgt ttatgaccaa aacggtgtac tgattggtcg
     2521 aagaaaaaat ggagtcttgc gttgtaccgc aaaagggatg gggcgtttga tcggctgaat
     2581 tgatcattct cataacttgt attttatcgt ttttcgcttg cttgaaaata ttgtcgagac
     2641 ttctaaagga acttagagtc actagaaaaa taaggagtag acttgatcta tcaacaattc
     2701 ccttcgggga gtgacggggt aggttttaac gattggtaac gtaaaaaatt ggtcaatcga
     2761 gtaaatgcgc ttgtttggat agtggtgaaa tgaatttgtg taaataataa gcgcagagta
     2821 aacaagaggg aatttagaag ttagacaagt tagaatagcg tctagattaa tcatgagcag
     2881 ctactaaggg atctagactt tgacgcaaac tcatggaata aggagtaggt cttctcgtaa
     2941 tggggaggac gcacaagaaa ttgtgtcgtg tgctgcagta catgtagata cttgcgagga
     3001 cgttgattat tggatcaatc gagcatttac cgctgtctac tagggtttct cgtttcggac
     3061 gccataaacg agtcgaaatt ttttatgtat ttttaagtaa acgaaaaacg ataaaatatg
     3121 aacaagtcct gaataaagtg aaaaaattga tataaaacat agagaaaatg aaatttacgt
     3181 aatggaggaa tgacaaatga aaaattatga tccgaatata cgattgggca cacatactat
     3241 taaggtttct ttccaacgtt gggattacaa aggatttgtg acgtttagaa ggggcggaaa
     3301 ttgtaaagga ttagatgttt tagcattaga cgaggatgat ttatacgatc aaacattgac
     3361 tgataatcca attggattcg gcttgctacc tgaagatgat gaaggtaatg aatggtttaa
     3421 aatgacgctt atgaatgata atggagacga attatctgtt gaagatactt ggtcatattt
     3481 gagtgattat attgtcagct ttgaaatcat tgaatttgta gcggataaag aagaataaaa
     3541 actggaggaa taaattttac agataaaggc ttagaaggag tcacgacgat taataaaaag
     3601 gtagtattac cttaggcatt gagtaagga
//
LOCUS       DADVXV010000157         3611 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.164, whole genome shotgun sequence.
ACCESSION   DADVXV010000157 DADVXV010000000
VERSION     DADVXV010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3611
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.164"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            11..478
                     /locus_tag="KB969_002840"
     CDS             11..478
                     /locus_tag="KB969_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870746.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            683..2347
                     /gene="alsS"
                     /locus_tag="KB969_002841"
     CDS             683..2347
                     /gene="alsS"
                     /locus_tag="KB969_002841"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBB6870747.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2360..3070
                     /gene="budA"
                     /locus_tag="KB969_002842"
     CDS             2360..3070
                     /gene="budA"
                     /locus_tag="KB969_002842"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBB6870748.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3200..>3611
                     /locus_tag="KB969_002843"
     CDS             3200..>3611
                     /locus_tag="KB969_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBB6870749.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYD"
BASE COUNT         1173 a          583 c          794 g         1061 t
ORIGIN      
        1 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
       61 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
      121 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
      181 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
      241 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
      301 agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac
      361 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
      421 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
      481 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
      541 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
      601 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
      661 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
      721 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
      781 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
      841 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
      901 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
      961 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
     1021 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
     1081 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
     1141 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
     1201 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
     1261 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
     1321 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
     1381 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
     1441 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
     1501 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
     1561 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
     1621 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
     1681 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
     1741 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
     1801 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
     1861 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
     1921 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
     1981 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
     2041 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
     2101 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
     2161 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
     2221 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
     2281 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
     2341 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
     2401 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
     2461 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
     2521 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
     2581 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
     2641 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
     2701 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
     2761 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
     2821 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
     2881 tcacttgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
     2941 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
     3001 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
     3061 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
     3121 ttttgaggag gaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
     3181 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
     3241 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
     3301 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
     3361 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
     3421 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
     3481 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
     3541 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
     3601 agggtatgat g
//
LOCUS       DADVXV010000158         3601 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.165, whole genome shotgun sequence.
ACCESSION   DADVXV010000158 DADVXV010000000
VERSION     DADVXV010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3601
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.165"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..1316
                     /locus_tag="KB969_002844"
     CDS             <1..1316
                     /locus_tag="KB969_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6870750.1"
                     /translation="IYSSFLLKFRGEIPLRNLETFQHSAIIISVIFIALNILLGAYVF
                     YNRMISDIVFVTVIGQVLMTLGIMVVTFAGRWFAFPRLVILLSFVLGTLFLSIYRILV
                     YKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSKKNNKHKVEAVILDNYYANIKNMIKDI
                     DIVYLASHIEETEKIKIYQLVTKNEKKLFLNTTFENLTLINPNIMNFEDESIIEASGF
                     RIQPEYELFKRLFDIIVSLVLLVIASPFMLFTAILVKVTSPGPIIYKQVRITKNQKEF
                     SIYKFRSMTATAEAKSGPVLAKSNDARVTPVGKFIRAVRFDELPQIFNVLKGDMSIVG
                     PRPERPFFVDQFNAENPYYYLRHNVRAGITGYAQVYGKYVSDYNSKLRFDLLYIKKYS
                     LMLDLKILLQTIKILFDKMSSQGLEEDENVISLAEIAFPNEKIFR"
     gene            1332..2372
                     /locus_tag="KB969_002845"
     CDS             1332..2372
                     /locus_tag="KB969_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6870751.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2391..3476
                     /locus_tag="KB969_002846"
     CDS             2391..3476
                     /locus_tag="KB969_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBB6870752.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
BASE COUNT         1285 a          523 c          670 g         1123 t
ORIGIN      
        1 caatatatag tagtttctta ctgaagtttc gtggagagat cccattacga aatttagaaa
       61 ctttccaaca ctcagcaatt attatttcag tgatttttat tgcgttgaac attttgttgg
      121 gtgcatatgt tttttataat cgaatgatca gtgacatcgt gtttgtcaca gtcatcggtc
      181 aggtattgat gacactaggg atcatggtag tgacttttgc gggccgctgg tttgcttttc
      241 cacgtcttgt tatcttactt tcatttgttc tcggtacgct tttcttaagt atctatcgta
      301 ttctcgtata taaactttat ttacgcgtaa gtcgagataa aaaggtcgtc attattgggt
      361 tagaaaagga tgtcgcacca gcaatccaaa attttggttc aaagaaaaac aacaaacata
      421 aagtcgaagc agtcattctt gataactatt atgcaaacat caaaaatatg attaaagaca
      481 tcgatattgt ctatcttgct tctcatatcg aagaaactga aaaaatcaaa atctatcaat
      541 tagttactaa aaatgaaaaa aaattgtttt tgaatacaac atttgaaaac ttgacattga
      601 tcaatccaaa tattatgaat ttcgaagatg aaagtattat tgaagcatct ggatttagaa
      661 tccaacctga atatgaacta ttcaaacgtt tgtttgatat catcgtttca cttgttttat
      721 tagttattgc ttcaccattt atgttattca cagcaatttt agtcaaagtg acatcaccgg
      781 gaccaatcat ctataaacaa gtgcggatca caaaaaatca aaaggaattt tcaatctata
      841 aattccgctc gatgaccgcc acagccgaag caaaatctgg accagtttta gctaagagca
      901 atgatgcacg agtaacgcct gtaggtaaat ttattcgagc tgtccgcttt gatgaattac
      961 cacaaatctt caatgtgctg aaaggcgata tgtcgatcgt aggaccacgt cctgaacgtc
     1021 ctttcttcgt cgatcagttc aatgcagaaa acccttatta ctacttacgg cataatgttc
     1081 gtgctggtat cactgggtat gcacaagtct atggaaaata tgtctctgat tacaacagta
     1141 aattacgttt tgatttactt tatatcaaaa aatattcatt gatgcttgat ttaaagatct
     1201 tgctgcaaac catcaagatc ctatttgata aaatgtcctc tcaaggactt gaagaagacg
     1261 aaaatgtgat ctcattggca gaaattgctt ttccgaatga aaaaatcttt cgctagttgg
     1321 gaggcgtaaa aatgaacaat ccgaaattca gcataatcgt accagtatac aatgcagaag
     1381 caactattgg tcgaacgatt gatattctaa aagaattgga ttatgaagag tacgaagtcg
     1441 ttttagtaaa tgatggatca acagatcaaa cacaggaaat cattcaagaa ctgattgaaa
     1501 atgatgaacg ttttgaattg attactacga ccaatcaagg gcccggatta gcaagaaacg
     1561 aaggaataag acagtcaaaa ggagaatatc tcttattctt cgatgcagat gacacgccag
     1621 taaaaacgat cttgtcagat tatgatcatt tgctagaaaa gagtccaaaa gcggatcttg
     1681 ttgttagttc gtttgttttt cgtacaatgg acgagggaag aatcgtttcc gaaaaagaaa
     1741 acttagttac agaatgtcac tatctaactc acgaagagtt tataaaagac atgtatcagt
     1801 taatgaatga acagttgatg tatgttgtat ggaacaaatg ctatcgtagc gatattctga
     1861 aaaataacca aattctattt aaaacttata atagttgtga ggatcgaata tttaacttac
     1921 attattatga atactgtcat caagtgatca tgaacccaaa agtagaatat atttatgaat
     1981 ttgaaggtgg gaaggggatc actaatcaat accgacctaa caagttcgaa acatttaaag
     2041 aattctattc attagcaaat actgtaacag acgatattaa taaagacggt atggcggcgc
     2101 ttcttttaaa agggacaact tcagttattt tttctattta tagtacctct gcaagaactt
     2161 caaaagagaa gaaagacgaa gcaaagcaga tattgagtga tccagtgatc cgagaagcca
     2221 agcaaattgc taagacggat tcttcagcaa aaaaaataac aaagttgctt tacaatatgc
     2281 cagctccact atttttatct gctgtaaaag ttggaagctt cgttgaagtg aaaatgccag
     2341 ggttaatggc tgctttgaag cgagtatatt agttaatgga ggaaaatata atgaaaagaa
     2401 ttttgcattt tcagggacga atgggtttag gtggagcaga gtctttcatg atgaatttat
     2461 atcgtaaaat tgatcgtaca aactatcaat ttgatttttt gatttatgaa gattatgcag
     2521 atgttcaaga ctatcattca gagattgaaa gattaggagg ccgtattttt gttgtaccta
     2581 atcctaagaa aaatattttt aaatatttaa tagaagtgaa taagttacta aaaaaagaat
     2641 ctttttctat agttcacaat caggtttatt ttggcggggg aattaattta tggttagcca
     2701 aaaagaatgg aatcagacag agaattgctc atagccatgc aactgaagat ggaaaatctc
     2761 aaaatattgt aatgaatgta ttgcgtaaat ttttaaccaa attgttgtta caaaatgcaa
     2821 cagactacct tgccgttagt caagaagctg gtgaaagtct gtttcaaaac cacccctttg
     2881 agatagttca taatggtatt gatttagagc tttatagtaa aaattcagaa gctaaggtta
     2941 ataagagaaa agaattggat atctcaatga gtacttttgt tgtgggaaac attggacgat
     3001 tagagaaaca aaaaaatcaa tcttatttgt tagagatttt tttagaaata ctaaaaatga
     3061 attctgattc ttacttgatt ttagtaggtg aagggtcact tagaaataaa ctgaaagcca
     3121 aagcagtaga attggatata gagaaaagag taaaattttt aggagaaaga aacgatattc
     3181 ccgagttatt atctgtgatg gatgtttttg taatgccttc tctttatgaa ggtctgccaa
     3241 tggttggatt agaagcacaa gcagcaaaat taaaattagt cttagcagat actatttcca
     3301 aagatacaaa gttaacaaat aatgtggatt ttgtatcatt agatgaaaca ccacaagaat
     3361 gggcaaaaaa agtaataaaa gagccgtatg ctaataaaat aacacaagaa ctaaagagtt
     3421 atgatgtttc gtacactact gaacaaatgg agagtatata tagtagagat cattaaaaat
     3481 gttcaagata ttttaggagt gattattttt gaaaatatgt tatttgatat tggcatacaa
     3541 tgatattggc aacttaaaga gattggtcaa tcgattgaac gaaaatgcag tttttattat
     3601 t
//
LOCUS       DADVXV010000159         3424 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.166, whole genome shotgun sequence.
ACCESSION   DADVXV010000159 DADVXV010000000
VERSION     DADVXV010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.166"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..1097)
                     /locus_tag="KB969_002847"
     CDS             complement(<1..1097)
                     /locus_tag="KB969_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBB6870753.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENA"
     gene            complement(1227..2603)
                     /locus_tag="KB969_002848"
     CDS             complement(1227..2603)
                     /locus_tag="KB969_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6870754.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2603..3259)
                     /locus_tag="KB969_002849"
     CDS             complement(2603..3259)
                     /locus_tag="KB969_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBB6870755.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3269..>3424)
                     /locus_tag="KB969_002850"
     CDS             complement(3269..>3424)
                     /locus_tag="KB969_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBB6870756.1"
                     /translation="GSLINNSSFMSNITTLGQSYLILISIIVLSVVFASSLMLIKKPK
                     EILSKIS"
BASE COUNT         1054 a          634 c          457 g         1279 t
ORIGIN      
        1 gcattctcat tagagaacac tccctttttt gtgacttttc tgaagctaga gtgaatactt
       61 tcaactgcat tagtagtgta catgattttt ctaatggcgc tgccataatc aaagagttgt
      121 tcaacatgag aaaagtttcg tttgcataca tctactgcac cagaataatg agaccaccga
      181 ttttgaaaac tgtcgaaggc agcgtgtgca gcgtttaaag aagaagcact gtagaatttt
      241 ttcatgtctc gacagacttc cttataatcc ttacttggga ggtatcgtaa cgcatttcga
      301 acaagatgaa caatacagcg ctgcacaatg acagaaggaa aaattgcttt tgcgccttct
      361 ttgagaccgg aaacaccgtc catcgaaatg aaaaaaacat cttctacacc acgtactttc
      421 agttcatcaa atacttgcat ccagcgattt ttagattctg tttgattgag ccataggcct
      481 aaaatctcct tgtttccttt aagatcatag ccaagaatgg tgtacacagc atattcttta
      541 gcttcatagt tttcgcgtaa agtgacgtac atacaatcaa cgaatagaaa tgcataacac
      601 ttggctaatg gccgagcttg ccattcttcc aattcaggaa ggacggcatc cgtgatatca
      661 gaaatcattt cgtgggaaat atcaaagccg taaatatctt caacggttgc ggcgatatcg
      721 cattgactca ttcctcgtgc atacatggaa agaaccttac cttcgatgtc ggagacatct
      781 cgttttctat taggaatcaa ctcaggttca aaagaagcct cccggtctct gggaacatca
      841 atgtttactt taccaaagct cgttttaagc gtcttattgc cataaccgtt tcgtcgattg
      901 tcatgtttct ttggctcttt agaatgggcg tcatacccta aatggttatt caattctcct
      961 tgaagcattt tttcaaataa gggaccaaac acatctttta aaacatcttg catatcctct
     1021 acagattcgg gttgataagt attcaaaatg gattcagcta acttctcagc atcaggattt
     1081 cttttctttc tagccatcgt gtaatcacct cttgatctta ttttagaaaa ataaaaaccg
     1141 tgaagcaacc acccgcctag gattgatggt tacttacacg gtttatatta cactctcatt
     1201 tttggtgcta aaaagcaccg aaaattttaa ttattgtcaa ttaataattc ttttggattc
     1261 cttcttaata tattgaatga agaaataatc aatgatacaa gaagtactaa actcataaat
     1321 ataactacat aaatcatgaa tttaggtaat acattgatat ctaaacttga taatgtcttg
     1381 ttaaatcctt cagcttctgc cccaccacct aattggctag atgcagattg tttagctatt
     1441 tgtttagcta tatcaccagt aaccttattc aatatattat tcccaagctt gtcagctgta
     1501 tattgagcta agaaatagga accaacgaat gcggggattg atataaatac catctcaatt
     1561 aggaattgac caaaaatttc taattttgat atacctaatg atagtaatac tgctatttct
     1621 ttctttctag cattcatcca taagaataat aataatgaaa ctacaactcc tgcaaatatt
     1681 aatgagccaa aaaataattt atttgaaatt gagtaaatac ctgatataga ttgttgtaat
     1741 gcagggtaat ttgatgaact tttaatcaaa ttatattctc tccaatttat atctaatttc
     1801 ccaagatctt ttattacact atcaagattc ttatcacctt ttacaaagaa tgttgcatct
     1861 tggtatacag ctgtatcttc ggtattacca taaactttag cagctgtatg aatatcagtg
     1921 attaatgtat tttcgtatag ttcttgtgct gcacttactc caccgctatt atgcccatcg
     1981 aatagacctt taatttctac ttctactgtt tcatctgcac ctttctcatt atcagcatca
     2041 aataaattag attttatttt tatcttatct ccaactttaa ggttattttt ttcagctaaa
     2101 tctttatgca ttaagatttt atttttatct tcattttcta aatgctttcc ttctactaat
     2161 ttatatgctt ctgatacaaa ttttgtttct tttgttgagt cgttaacccc agttaacata
     2221 actgttcttt taaaattctt tgctctttca ggtgattgat tcgcaagagt ctcttgagtt
     2281 tcaataatat cataatcaac taaatctgca acactgttta ttctttttac ataggagtct
     2341 atactatctg tttgagatat ctttttaata tcttcacctt ttacatttcc cccacctcta
     2401 ggtgttcctg gatttacttg tctatttatc tccatagaaa aactatttgt tatattagca
     2461 aatgtttctt ttgaagctct gtccgtagca tctttaatag ataaactaat gagacttaaa
     2521 gttgacatag ataaaataac taatatgata attaatgatt ttaaactttt tctagttaca
     2581 taagcaaatg cattttttat cattattcaa cctccaaatt cattttattt acttttttca
     2641 actttttacc acttagttct aaaatgatat ccgcagaatc tgctacttcc ttactatgtg
     2701 ttacaactat tacacattta tttctatctt tagctaatgt ctttaatata ttaattattt
     2761 ctccagcagt aacactgtct agattaccag taggctcatc agctagtatt attggagcat
     2821 ctgataccaa tgctctagca atagctactc tttgttgctg tccaccagat aatttcataa
     2881 catttctttt tatttgtttt ttatctaaac ctagttcaaa caagatactt tcatctgctg
     2941 atttatttac taatctaata ttttcaattg gtgataaata atctattaaa ttatagtttt
     3001 gaaatactaa agatatatta ttttttctat gattactata tcctttattt tgtatatctt
     3061 cattcttaaa caatattttt cctgtttgag gtttatcaag tccagcaagt aaggaaagaa
     3121 gtgtagattt tcctgttcct gactttccta ctatcgcata aaacttccca agttcaaatt
     3181 tttgatttac tcctgacaaa actttttctt tagaatttgc ataactatat gctacattct
     3241 ttatttctaa tatatccatt attttctcct aacttatttt tgataagatt tctttaggct
     3301 tcttgattaa cattaatgaa gaagcaaata caactgataa aacaataata cttattaata
     3361 ttaaataact ttgtccaagt gttgttatat ttgacataaa actactatta tttattaaac
     3421 ttcc
//
LOCUS       DADVXV010000160         3331 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.167, whole genome shotgun sequence.
ACCESSION   DADVXV010000160 DADVXV010000000
VERSION     DADVXV010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3331
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.167"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..729
                     /locus_tag="KB969_002851"
     CDS             <1..729
                     /locus_tag="KB969_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBB6870757.1"
                     /translation="TIIYSTMSDIKKNTKVGDATIIRFCQKIGFSGFSDLKIEIAKED
                     FSQKKEHPTSVKYYDEIANSLTEALYSTIRLLDEEKLNEAIKMITQSKNIYIFGVGSS
                     GNTSLDLENMFLRVGVQAKAVLDPHFQAQVASLLTVNDLVIIFSLSGKTKDTYDSLKI
                     AKKNGAKIIAITNYIHSPIGKSADLVLQTAIEEFLNGGSLAGKISQLYICDLLVHGYE
                     QNNNIDSVELREKVLRSIIDKSIE"
     gene            complement(1412..1510)
                     /locus_tag="KB969_002852"
                     /pseudo
     CDS             complement(1412..1510)
                     /locus_tag="KB969_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1775..2230)
                     /gene="tnpA"
                     /locus_tag="KB969_002853"
     CDS             complement(1775..2230)
                     /gene="tnpA"
                     /locus_tag="KB969_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBB6870758.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2473..3331
                     /locus_tag="KB969_002854"
                     /pseudo
     CDS             2473..3331
                     /locus_tag="KB969_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         1099 a          578 c          581 g         1073 t
ORIGIN      
        1 actattattt atagtacgat gagtgatatt aagaaaaaca caaaagttgg cgatgctact
       61 attattcgct tttgtcaaaa aattggtttt tctggttttt ctgatttaaa aattgaaatt
      121 gcaaaggaag actttagtca aaaaaaagaa catccgacta gtgtaaagta ctatgatgaa
      181 attgctaata gtttaacaga agctctctat tccactatta ggcttttaga cgaagaaaaa
      241 ttgaatgaag ccattaaaat gatcactcaa tcaaaaaaca tatatatatt tggagtggga
      301 tctagtggaa atactagtct tgatttagaa aatatgtttc ttcgcgtagg agttcaagca
      361 aaagctgtac tagaccctca ttttcaagcc caagtcgctt ctttattaac agttaatgat
      421 ttagtaatca ttttttcttt atctgggaaa acgaaagata cttatgattc attgaaaata
      481 gctaaaaaaa atggcgcaaa aattattgct ataactaact atattcattc acctatagga
      541 aagtctgcag acttagtttt acaaacagcc attgaagaat ttcttaatgg tggatcttta
      601 gctggaaaaa tatcacaact ttatatttgt gatctattag ttcatggtta tgaacaaaac
      661 aataatattg attcagttga attaagagaa aaagttttgc gctctattat tgataaaagt
      721 attgagtgaa ctacccccac ttagctaaac ctaacggttt ttaacgattg aagtaggcaa
      781 ttcttgggat gagagcatac ttgatagctt attttttact aatagcggtg gctcttattg
      841 accaaatatc cctgtagttc ctacggttct tgattttatc taaagatatt tttatcgtgg
      901 aagctattga tcaacttgaa agaaaaacgt gtagctcatt atcactagtt tatcgagtat
      961 ggatgaagca atggatcatc ctctcttaaa taaatttatt aaggatctga tccttcaaat
     1021 tttttccatg atcgatgagc aggaacctac tgaatctaaa cgacatcggg cacaaggaat
     1081 tattaagatt gctaagcgaa tgttttctat aaagggtgtt ctaagctata cagtgttaat
     1141 tcaaaagatt cccaatcatc ttgtttataa gaacaacgtt gaagattaaa aaagtgtttc
     1201 aatgctaaaa ttgcaaaata cttcaatgtt atgagacaaa ctgtctataa gaatcaattt
     1261 ccacccattt catcacttgt taaaagttta tgatcctttt gatttttata ttaatttatc
     1321 tgtatttaat acagatttta tttattagtt catctgccta ttgtatttta ttttgttgcc
     1381 ttaccatctg aagtaaatat actcttaatt gtcaaattaa gttagacaga tcatcaatac
     1441 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaagat
     1501 tatttctgcg ccagcatttt ctaatgtttg aatttgtgtt ttgtaatctt ggttgcttgt
     1561 gctaattctt gaatagccgt aaattgccaa aatttcatca ccctttctgg acataagttt
     1621 ctgacaccag ttaaaatcaa gtctatcagt aacccataca cccgtgagga cgggtgtatt
     1681 tttaatcccc ctagaagggg tcgacactcg ctgcccctta aaaggggatt tttaaaagac
     1741 cgccaactgc tcatcttcac tcacttactt ctctttattt tttaaatggt tctacgtact
     1801 ctcttttact tataatatat cgaatgcgat catcagcttc ttgttcacgg atgtattttt
     1861 catttgtctt ttgattcaat ccgactgtac tcacatagta tctcttcgac caaaaggatt
     1921 tgtttccgta tttatatttg agatttgcgt gctgctcgtg gattagtacc gcactacgac
     1981 ctttcagata ccccataaaa ctggatatac atatttttgg tggtactcga acaagcatgt
     2041 gaatatgatc tagcattgca tgtgcttcta tgatttccac atctttcatt tcgcacaact
     2101 tcctaagtat ttttccaaga tcttttcgta attgcccata gattactttt cgttgatatt
     2161 ttggtgtaaa aataatatga tacttacaat tccaacgagt atatgctaaa cttttatcgt
     2221 catttgacat gaaaaaactc ctttcgatct gatgagcggt tggtagccac tcactagtat
     2281 atcgaaagga gtttttatcg ctaaagatac ttcttccacg cgtagaaacg cgcggttttc
     2341 ttgtttcgca cgctttacgc acaaaactga ctgaagtcat taagaaaata aaagggtcta
     2401 aaacttttaa gttttgtacc gacccccaaa agttagacca aaaaatctaa cttttggagg
     2461 tcggtatttt ttatggctaa gtatactttt gaacttaaat taaagatcgt tcatgattac
     2521 ttggatggta aaggcggaag tgattatctg gcaaagaaat attccattaa ggctccatca
     2581 caagtgaagc gctggatcaa tgcctatcaa gaatttggtg aagagggtct agtaagaaag
     2641 cgacaaaaga aaaaatattc tgttcaattt aagctggatg cgatagagtt atatctaaca
     2701 agtgagctgt cctatcgtga agttgccaac acacttaaca tgaacaaccc taatttgatc
     2761 gctagttgga tgcgtcaatt ccgtgagggt gggatcgatg gactctcaaa aacgaaagga
     2821 tgtccaccta tcttgtctaa gaaaaatgaa cccaaaaata agaaaaaatc tacaactaaa
     2881 gcaacgtcta aagaacgtga acgcatcgag gagttggaga aacgagtccg ttcccttcaa
     2941 attgaaaatg cctttttaaa agaattgagg aagctgcgaa aacaggaagc ccaacaacga
     3001 cgaatgaagc aatcgcacga atcatcgcaa gcctccgagg accgtttaaa ttagttgagc
     3061 ttctagaaac tttaaagttc cctaaggcaa tctttatgta ctggcaaaaa cgattggacc
     3121 gtaaaaatcc agatcaagag attgaagcgg aaatgcttaa agttcgggag aagcacaagg
     3181 attatggctg tttacggatg accaatgaac taagaaaccg cggtttctct atcaataaaa
     3241 agaaagttca gcgcctgatc aagaagctag gaataaaagt aacgacatac acacgtaaat
     3301 cacggcgcta caattcttat cgaggacaag t
//
LOCUS       DADVXV010000161         3300 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.168, whole genome shotgun sequence.
ACCESSION   DADVXV010000161 DADVXV010000000
VERSION     DADVXV010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.168"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(51..2522)
                     /locus_tag="KB969_002855"
     CDS             complement(51..2522)
                     /locus_tag="KB969_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBB6870759.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            2795..>3300
                     /locus_tag="KB969_002856"
     CDS             2795..>3300
                     /locus_tag="KB969_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870760.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
BASE COUNT          975 a          664 c          595 g         1066 t
ORIGIN      
        1 aagatacacg agtggttgtt cttttttact cttttttgag atacttttcg tcaattttct
       61 cgtttaaata tcgatagaaa ttttttagct acgcgactaa acggcttttg ctctttttca
      121 tttttacgtt caaacaaata ttctaccaat gtggtcaaat gcctaaaaat cgaatctgcc
      181 gagaaaaata gaatgctcaa cagcaaaagt gatacagctg agataccggt gattgaaaac
      241 agcttatgca aaaagatgac cgaaaaaaag ttaccgctag cacagaaaag aatgatctga
      301 cttctgaatt tattcagcgg tgaacagatt ttatagagaa cgaggaaccc tactgcaatc
      361 aaaagcatgg tagatgctgt agaaacatct gttttattta gattcaaagt caccccgcag
      421 atcaccaacg caccgactac gatcatatct gttagtccac ctggcacagc tttttccatc
      481 acattcatga tgaatttccc tctgattcgc tttttgtttt cttctagagc aagcaagaaa
      541 gatggaagtc cgatagtaaa caaactaatc aatgtgattt gtgatggttc taaaggatag
      601 gtcagagcaa agatcactga aaacagtgag agcaaaaagg agaaaatatt cttcactaaa
      661 aacaagctgg ctgatcgctc aatattgttc acaacgcgcc gtccttctgc aacaacttct
      721 ggcatgcgtg aaaagtcaga atcaagtaag accacttgtg aggcctgcat ggcggcttca
      781 tttccggaag ccatcgctat actgcagtct gcttctttca tggctagaat atcattcacg
      841 ccatcacctg tcatagctac tgtattgtta cgctttatca attgaacgaa gattttcttt
      901 tgttctggct tgacgcgtcc aaaaactgta tatttttcga cagctgcttc atattcttct
      961 tctgataatt tagatgcatc aacgtactga tcagcatgtg aaatccctgc ttggacagct
     1021 acattggata cggtgagcgg attatctcca gaaatcactt tgatggctac ttgctgtttt
     1081 ttgaagtaat caaatgtggc tcttgcttct tttctgatag gattagcaat cagaatatag
     1141 cctaatggtg tgactgcttc tgtcaatact ggttcttcaa gaatcccatc gtacacacca
     1201 aagaccaaca cgcgatagcc tttttcagcg aaagaaacaa actcttccgc atattccggc
     1261 aattgatcgc gcaaaaccat ttcgggcgct cctaaaacat acaccttgtc tgccaacgct
     1321 acactgctga atttttggac agaagaaaaa ggaataacat ggtgatagga ttgatcagtg
     1381 gtttttgtaa aatatgcttt aacagcttcc attgttgcat tgtctcctgc catcgctttt
     1441 gcatagtcag caatgcatgc ttccaattga tctgactgac tgattatttc ttgtttttta
     1501 gagacgatca ttttttgaac agacatttta ttttctgtga tcgttcctgt tttatctaca
     1561 caaaggacat ttacccttgc caatgtctca atgcttttca tattgtgtaa aagaactctt
     1621 tgctttgcta gtttagtcgc acttaatgct aatgcaatcg tcgtcagcaa gtacagtcct
     1681 tcaggtatca taccgatcaa tgctgcttcc attgcaacga cactttcttt gatcgtgttt
     1741 ccattaaaaa agtaactttg agaaaaaagc aggataccga taggaataat gatgatccca
     1801 atccatttga tcaattgatt aagagaagca atcatctccg actgttctcc ttctcccatt
     1861 gtcttggctt tgactgtcag ctgggaaata tacgaatctg ctccaacttt gtctaatcgg
     1921 gcgtaagctt ttccggaaac aatgaaactg ccggacatta atggatcacc tatttctttg
     1981 gttatttcat ctgcttcgcc tgtcaataaa gcctcattaa cttgcagttt cccttccacg
     2041 acctctgcat ctgctggaat ttgatatcca gtctctaaaa taacaatgtc atctattaca
     2101 aggtcttcta tatctattgt ttgttctatc ccgtctcgta tgacattgac ttttgctgta
     2161 tttaaaacat ttagttcgtc caagatcttt ttggatcgaa tttcctgaaa aatggcgatt
     2221 cctgtattgg ctatgataac tggtaaaaaa gtcaagttct tataggattc tactaaacaa
     2281 agcaaaatgg ctaagataag aaagatcaaa ttgaaatacg taaatatgtt ttccaatacg
     2341 atttgctgat ttgttttgaa tgtgggatcg actgaattat ttgctgcacc tttttctatt
     2401 cgttccttga cttgatctgc cgttaatcct tctttatacg atggaaaaag acggatgact
     2461 ttatctgatg atctttgtgt tactttcttt tttttacttc gatttatcca tttattcttc
     2521 atgtggctac ctcgattgat ttcgttttct ggatatttcc aaacttctcc tatccagtat
     2581 agaacagata tggaaagtgt tcctcacatt aagcttgcaa acacctttca ttcctgtcat
     2641 atagcaaaaa aaaagggttc tataatattt tgtgttggtg gaaaatcgaa ggcgattttc
     2701 tactaacact ttttcttcgt ttcaactcaa aaagagactc acttttggta aaatttagtc
     2761 gaccaaaacg tcatcctacc aaaggagtct ctcaatggat aatcatacta gaaaattact
     2821 cggattaaca gataaacatt tattttttga tgaagaatgg ctgattgaaa aagaatataa
     2881 aggcgttcaa gcgcagttta ttaaaggaaa attggatgac tcttcttcct attgtgaaca
     2941 ctgtcgatcg gttcgtatta tccgcaacgg ttcctatacg acacgcactc agatgttgaa
     3001 agtcaaagaa aagttaacta ttttagaatt aaaacgtacc cgttttctct gccatgattg
     3061 tggaaggacc ttttctgcga aaacggactt agttgatgaa catcatcaac taacaaagga
     3121 actgaagcag gtgattctca tggaactgta cgaaaatcaa tcacgtaaac taatcgctaa
     3181 gaagtacttc gtctcggatg ggacggtgac acggatcttg cgtgaagcaa cgaagcatta
     3241 ccagccacgt atgaacttcc ttccgacggt gttgtgtatg gatgagttca aatcaatgaa
//
LOCUS       DADVXV010000162         3233 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.169, whole genome shotgun sequence.
ACCESSION   DADVXV010000162 DADVXV010000000
VERSION     DADVXV010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.169"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            296..610
                     /locus_tag="KB969_002857"
     CDS             296..610
                     /locus_tag="KB969_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870761.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(663..1436)
                     /locus_tag="KB969_002858"
     CDS             complement(663..1436)
                     /locus_tag="KB969_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870762.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            1541..1786
                     /locus_tag="KB969_002859"
     CDS             1541..1786
                     /locus_tag="KB969_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870763.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            1942..2793
                     /locus_tag="KB969_002860"
     CDS             1942..2793
                     /locus_tag="KB969_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBB6870764.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            2826..>3233
                     /locus_tag="KB969_002861"
     CDS             2826..>3233
                     /locus_tag="KB969_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870765.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATT"
BASE COUNT         1194 a          446 c          553 g         1040 t
ORIGIN      
        1 atcttgttgt ttctactagt aatgtatctt tttggaaact atgtaacgat gtaaacaaga
       61 tttttttcag aagaaaaaac gataaaagtt gtgataaacg atttaaaaaa taggagaaaa
      121 tatatcaagc gcatggtatg aaacgcacat ttaaaaagat tcgactaact aaaaaaataa
      181 gtttacaaag cattgttgtg tattacaagt gatctataca ctgaaaaatg atagagaaaa
      241 tctgatacgt ccgcaacaat ggacaattga aaatgaaagt gaggaaattg gaagaatggc
      301 tgatgaaaat aaagttgttc cgcttgaaac actagtgata aataaggaag agtttgagca
      361 actttttctt gatttttttg ttcaatatga caggatttat gattttagtt cgtcactaga
      421 tttatttgaa ttagaggcag aaataataga aaacagtcga gaggagaatg gtaaaatcat
      481 catttcagta gaaaaattca atgaattatt ctcagaaaca tttgaaatag atacagatta
      541 ttatcaacca caagaagttt tccaatcatt tagaaatcag attattcgct caggtaagac
      601 cgtaaactga aaaacaataa aagaaacgtt gaaagaataa ttattccttc aacgtttctt
      661 ttttagaatg ttttaatgac caaagcagtt tcattgtcag gcttaggtaa ttcatgaaat
      721 cccgtattta tagtgctcaa ttgatcaact aaccatgttt tactttttga attgtagata
      781 aatctaaaat taatatcgtt attatcgtgt tgaaggggcg tctccaaata atctgctgta
      841 tattcatagt caacgtaacc tgctaataca aaagagagta tccctttatt taatgttaga
      901 tttaatggat aatcatacga ctttattttt ttcaacttca tattgtacat atcttcagcc
      961 ataaaagttg agttcgtgat ttcatcttgg gtctcattaa aaaagttatc cgaataatcg
     1021 cttatttttg aaaagtcttt attggcacca gcctcaaaaa attgttcaac tttttcagta
     1081 taaagttgtg ctaacgctcc tttttcaata ttaactttaa tattttcatg tctatcaatt
     1141 tgtgtgctgt tcagtaaggg aagatcagct tttagtttta tatcgtcttg atttctttca
     1201 atttcaattg gcaaaatctt ttcagtagat tcagtttctg ataaaggaac atctagtttt
     1261 ttatcatgat aataagcttc aaatccatct ggaaccggaa aaaaatgtat tgggtaattc
     1321 ttttctgagg ttgttgtact agtttccgta cttgtagaac ttgtgtcaga agtggtacac
     1381 ccgcttatag ttccgatgag taaagcgcaa gttagaatga ttgcaaattt cttcaaaaaa
     1441 attcctcctt aaaattgaat atggactaat actagtccca ttgtagcata ccgaatcttt
     1501 aagattaata agaaaaagga ctaattttag tccaaaaggt gtgctattct tgaaagagga
     1561 aaaaattatt gataaagaaa atgtaatcgg tagcaatatt agacgagtcc gattagaaaa
     1621 aggaattggt caaaccgagc tgattagaga cctacagctt cgtaaaattg ctataactag
     1681 ggaaacgttg gttaagattg aaggtggccg ccaacacatt aagttggatc aattgaaagc
     1741 catcaaagat attctacagg tgtcttatga agatttgctt caatgactac ttgtagtcat
     1801 ttcgtttgaa attattatgt tacaccctta tgtgtcacga agaaatactg gtataataat
     1861 gaatgggata tgtaacgata gggtatactg ttatgttgcc taataaattg tggatcaaaa
     1921 tacaagaatg gagggatatc cttgtataag gcatatgaat tggattttac aaatgctgac
     1981 ttaaatgcat tctcctcaag ctcgcaatca tatacacatg tagtaaatca aatagatcac
     2041 aaccaaaaat ctattaacaa gagaatagaa aatctatttg aaagtgaaaa tgatttagtt
     2101 gattattatt ctaaggacag caaaattcta gatgcagacg aaattattaa agattggttt
     2161 ccaactataa aagcagatat ttttatatct cactctcatg ctgatgaaaa attagctata
     2221 cgttttgcat catggctatt tgaaaatttt ggtcttactg catttattga ttcttcggtt
     2281 tggggataca gttctgattt attaaaaaaa atagaccaaa aatattgcta taaggaacaa
     2341 acaaaaacat atgattatga taaaagaaat gtaacaacta gtcatgttca tatgatgctt
     2401 tctacagctt taaataatat gattgatagt acagaatgtc tgttttttct taatacacct
     2461 aattcaatta gtttgagcaa tgaaatcact aatgaacaga aatttacgta ttcgccatgg
     2521 ctatatagcg aactgacgac agcttcaata gtggaaaaaa agaatccacg attggaaagt
     2581 aatcctcaaa tgagcaccga ggatgttaga agcattataa agcactattc ttcgcaagaa
     2641 aatctgcaaa taaaatattc tttaaattta agtgaattaa cttatttacg aaaagctgat
     2701 ttgaaaaaat gggctttaga tgctgtggaa tgcactaaag gaagtaatac attagatatt
     2761 ttatataaaa acaccatttt cactaatctc taatcaattt actgaatcga aaggaaccgg
     2821 gtagaatgga taagaaagtt ttaataaaga ggttctctga agctattgaa aaaggaaatg
     2881 cagcaatatt tgcaggtgca ggattatcga tgtcacaagg atatgtaagt tggccggaac
     2941 tacttaatga tcctgcaaca gaaatcgggt tggattctaa aaaagaaaca gacttagtta
     3001 ctctggctca atattataaa aatgaaaatg gtggatcaag aggaattttg aatcagatac
     3061 ttatggataa ttttggtgaa gaattagaaa tatctgaaaa tcatcgaata ctagcaagtt
     3121 tacctattga aacttattgg acaactaatt atgatcatct aatagaaaaa tcaatccgag
     3181 aagcttataa aaaccctcag gttaagaaaa attatactca gttagcaaca act
//
LOCUS       DADVXV010000163         3119 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.170, whole genome shotgun sequence.
ACCESSION   DADVXV010000163 DADVXV010000000
VERSION     DADVXV010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.170"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..506
                     /locus_tag="KB969_002862"
     CDS             <1..506
                     /locus_tag="KB969_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870766.1"
                     /translation="IQSIFGIEEVFVGDKCIFFDQPLLSDGYGIDETDIFAKVNSIFS
                     GKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTISFSPSMM
                     FEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILLPENWAELRK
                     LVEYGII"
     gene            493..1914
                     /locus_tag="KB969_002863"
     CDS             493..1914
                     /locus_tag="KB969_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBB6870767.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            1927..2934
                     /locus_tag="KB969_002864"
     CDS             1927..2934
                     /locus_tag="KB969_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBB6870768.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            2946..>3119
                     /locus_tag="KB969_002865"
     CDS             2946..>3119
                     /locus_tag="KB969_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase family protein"
                     /protein_id="HBB6870769.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQ"
BASE COUNT         1103 a          399 c          523 g         1094 t
ORIGIN      
        1 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
       61 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
      121 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
      181 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
      241 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
      301 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
      361 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
      421 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
      481 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
      541 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
      601 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
      661 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
      721 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
      781 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
      841 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
      901 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
      961 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     1021 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     1081 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     1141 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     1201 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     1261 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     1321 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     1381 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     1441 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     1501 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     1561 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
     1621 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     1681 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     1741 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     1801 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     1861 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     1921 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     1981 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     2041 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     2101 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     2161 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     2221 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     2281 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     2341 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     2401 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     2461 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     2521 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     2581 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     2641 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     2701 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     2761 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     2821 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     2881 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     2941 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     3001 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     3061 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcag
//
LOCUS       DADVXV010000164         2925 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.171, whole genome shotgun sequence.
ACCESSION   DADVXV010000164 DADVXV010000000
VERSION     DADVXV010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.171"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..315)
                     /locus_tag="KB969_002866"
     CDS             complement(<1..315)
                     /locus_tag="KB969_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBB6870770.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYN"
     gene            complement(318..1949)
                     /locus_tag="KB969_002867"
     CDS             complement(318..1949)
                     /locus_tag="KB969_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBB6870771.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            2253..2924
                     /locus_tag="KB969_002868"
     CDS             2253..2924
                     /locus_tag="KB969_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBB6870772.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
BASE COUNT          954 a          556 c          408 g         1007 t
ORIGIN      
        1 attataacag ataacctcaa tcccaaattc tgccaaattg cgaatcgtct gtttataatt
       61 ctcaatgtat tgatctcgtg ttggtaaacc aattttgata tcatcatgaa cattaacact
      121 ctcaataact ttcaaggtaa gtccattggc ttcgacttca tcttttaaag atttaattcg
      181 ttctctcggc caaacctctc cggctggtat atccattaat gttccaacaa ttcctttcat
      241 tgctgggatc tgacgaattt cttgtagtga gattttttct tcatttgccc cataccatct
      301 aaaagtcatt tccatagtta ctttcctcca acttctgtta tatatttatt gattgtttta
      361 cgaactgctt gaggacctac tagcatttcg caaaagattt tttcagtttt ctttcctacc
      421 ccaacttgat ataaatctaa accaaagatt tctttatttt ctaaaatttc ctgtaccgca
      481 caatgaatct ttgaaggatc ttgttcacct aatttcaata ctgataattt atcctgcaac
      541 tctaccaata acggatcagg acttggcaca aaattttccc cttgatcatc gactgccagt
      601 aaataacgta accaagcagc aatagcgata ggaataaatg ttagattttc tgcatttccg
      661 tctttttcga catacttttt aattgtttca ccatagcgaa tcgctacttt ttgagaagta
      721 tctgttgcaa ttcgttgtgg tgtatctgga atatagggat taggcaaacg tttattaatt
      781 acttcatcaa taaattgttt tggatcaata atgcctggat tttcaactac tggtaaacct
      841 tctaaataac ctattccttt gattaaacca accaaatcat catcctgcat ctctgctgaa
      901 attgattgat atcctagcag acaacctgtt actgccaaag cagtatgaag tggattcaag
      961 cttgtcgtaa ccttcatgat gtctgcttta tcaaccgtct ctctatctgt cataatcaca
     1021 ccagcctttt ccaatttagg ccggccattt ggaaaactat cttcaataac taaataatga
     1081 actacctcag tattagtgaa agcagcaata ttggtatgtt tttttgtgtg aatgatatct
     1141 aaatcctcga gccccatcat caatagatct tcctttacat tctctgaagg atttggcgta
     1201 attcgatcaa tcatactcca aggaaaagtc actttttctt tatcctttaa ataagcaata
     1261 aatttttcag aaacatatcc ttctttttgc caagcttctg caatcgtaaa aatactatct
     1321 tgaaaacgtt gaccattctg tgagaaatta tcagtagaaa ccatcgcaat cggcaactct
     1381 ccagcattaa atctgctata taacaaggat gttacaatac tcatcgtatg ttgaggattg
     1441 ctaggtccag atttgatatc agctttgact accgaaaaga attgcccttt agaatctttt
     1501 aaactgtaac ctttttcagt aatagtaaac gttgtaaact gtaatttagg atcttcaaaa
     1561 tatttaacca ctctttgata gtccgctata ttcttcggat tgcaatataa actatcagcc
     1621 gttactgcca aaagtctttt tttgagttca ccatctccac tcataacaat ttccaaaatg
     1681 tcattgttat agtcatgata agctttttcc actacttctt catcaaatgt ttcacacaca
     1741 actactcctg tttctaattc attttgatct gctaagcatt gagcaatttc tgcatgaaat
     1801 cctcgataaa gatttcctcc accaaaatga agccatactg gatgttgctg gccttcttgc
     1861 ttaacttctt tgacatcaaa acacggcagt agaatctgca tttcattgaa ttcttcgata
     1921 gaattttgcc aatttttaat cgaaaccata attaacctcc tcaaactgat atgttagttt
     1981 tgatacattt tatattttaa aacccattgt aaccgttgtc aatataaaaa gggaataaac
     2041 ttgctttttt ctaccatatc agaatgattg tattttttat tcagaaaaat aaaatactcc
     2101 ttctttttgg actgatttta tcgaaactta ttttttcttt ttttcatgta ttcttttatt
     2161 tttataacta gtgtattact tcaaaatttg atattatatg gcatgaacag aattaaaata
     2221 tcagttaaaa taaaagttaa ggagcattgt gtatgacaat taaaactagt ctccaaaatc
     2281 aagcttacca atctattcgc cgacaaatta tctatgctga cttagaacct ggaaaaaaag
     2341 tatcagaaaa aaaattagaa gaaacacttt ctattggtcg tacaccaata cgtgaagcac
     2401 tgattcaact ccgacaacaa ggtcttgttg atacaattcc tcaaagcgga aattatatct
     2461 cattaattga tttagattcg gccaaaaatg ctcgatttgt cagagaacat ttggaacgac
     2521 aaattatgtt agagtgttgt gccaaaatga ataaccaaaa aaaacggatt ttagaaacta
     2581 taatttcaga acaagaaaaa gctgttagtc aaaaaaatgc tcgtagtttt tttcataatg
     2641 ataatttatt ccataaagct tgttttgaaa ttgcagagcg agaagaagta tggcaatggt
     2701 tagaaaataa caatacacac ttagaacgat ttcgatggct acgagtaaaa acggaaggat
     2761 taaagtggga aaaaattatg gaacaacatt atcaactatt tgaggcatta acaaaacaag
     2821 atccagaaga agctaacttt ctaacatcgt tgcatcttca tttaatgctt aatgagcaaa
     2881 atattgtttt agctactcat ccaaaatatt tcaaaaatat ataac
//
LOCUS       DADVXV010000165         2915 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.172, whole genome shotgun sequence.
ACCESSION   DADVXV010000165 DADVXV010000000
VERSION     DADVXV010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.172"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            226..915
                     /locus_tag="KB969_002869"
     CDS             226..915
                     /locus_tag="KB969_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBB6870773.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            929..2431
                     /locus_tag="KB969_002870"
     CDS             929..2431
                     /locus_tag="KB969_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBB6870774.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            2444..>2915
                     /locus_tag="KB969_002871"
     CDS             2444..>2915
                     /locus_tag="KB969_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBB6870775.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKIT"
BASE COUNT          941 a          405 c          565 g         1004 t
ORIGIN      
        1 gcgacttttt tttcagactt cgttaaaaat ggataatttt ctttaattaa atagatataa
       61 ctcatacaaa ctcctctaca atttcaactt ttctccatta tactccaaaa taataaaaaa
      121 aactcctaaa tactccattt ttatctttac ttttatgaaa gcggatgcta tattgttttt
      181 ggagttgtta tccaaaaata ataaaaaatt ggagtgttta ggataatgga taaaaagagg
      241 tttttagatc ttatttcaaa aggtttgatt gtttcctgtc aagcattacc tggtgaacca
      301 ttttacaaag aggaagaaag tttaatgcct tattttgctt tggctgctca aagggctgga
      361 gcagttggta tacgtgcaaa ttctgttcga gatattattg aaattagaaa gtgtgtatca
      421 ttaccaatga ttggaattat taaaagagat tatccaccag aatctccatt cattactgcc
      481 actatgagag aagtagatga attagtagaa accggtgttg aggtaatcgc tcttgattgc
      541 actcttagaa atcgacatga tggactatct ataaattctt ttattactaa aataaaagaa
      601 aaatatcctc atcagttatt tatggcagat atttctacat ttgaagaagg caaaaatgca
      661 tataaagcag gaatagattt tgtaggaact actttaagtg gatatactga ggaaagtaaa
      721 aaacaagatg ggccagatat agatttgatt aaaaaattgg tagaagaagg gatttgtgta
      781 attgctgagg gaaggattca tactccagaa caagcaaaag agataaaaaa aataggagtt
      841 gcaggtattg ttgtgggtgg tgctattact cgaccacagg aaattgcatc aagatttgtt
      901 aaagcattaa gttaggggga gaaataaaat gtttaaaaaa ttttcacaat taggacgcgc
      961 tttcatgtta ccaattgcta tattaccagt agccggatta ctattgggac tgggaggagc
     1021 gttaacaaat gagagtgcta taaatgctta tccattttta gatcaaccgt ggttgcatac
     1081 aattttaagt attatgagtt atgctggaaa tgcagttttt gcaaacctag cactaatttt
     1141 tgcaattggt attgctgtag gacttgcaaa tggagataaa ggaacagctg gtttagctgg
     1201 tggagtagct tatctagtat atactgcaac tattagtggg tttcttgaac ttttttcagc
     1261 aaaagatgca acactagata caggtgtagt gggatcaatt gttgttggtg gtactgttgc
     1321 atttttacac aatcgttata gaaaaattga attaccacaa ttcttaggtt tttttggagg
     1381 atcaagattt attccgattg tttctagttt agctgcaatc attattggtt ctttctttta
     1441 tttaatttgg ccaccaattc aaaatggttt agtagttgct ggtgaacaaa ttgcccaaat
     1501 gggtagttta ggaacttttt tatatggttt tttattgcgt ttaacaggtg ctgttggact
     1561 acaccacacc atttaccctt tgttctggta tacatcttta ggtggtaccg aaactgtagc
     1621 tggatcaaca attgctggag cccaaaatat tttctttgcc caactagctg atccaaacca
     1681 cactggtctg tttacttatg gtactagatt ttttgcagga agatttgcaa caatgatgtt
     1741 tggattacca gcagcatgtt atgcaatgta tcgtgcaatt cctaagaaaa atcgtaaaaa
     1801 gaatggtggg ctttatttta gcggggccct tacatcattt ttaactggaa ttactgaacc
     1861 agttgaatat atgtttttat ttgttgctcc ttggctttat gtgattcatg cattcttaga
     1921 tggattatct ttttattttg ctgatatctt aaatattcgt gtagggaatt ccttttcagg
     1981 tggtttgatc gactttttat tattcggtgt acttcaaggg aatgacaaaa ctaattggtt
     2041 aaaattaatt ccttttggta ttgcatgggc atttatatat ttctttgttt ttacattctt
     2101 tatcaaaaaa tttaaggtag ctattcctgg aatggaagaa gaatcagaag ttcattctga
     2161 aaaagtaata aacaaaaata catcattaca tgaagagtct cttatcatta ttgaagctct
     2221 tggtggaaaa gaaaatattg agtctgttga agcttgtgca actcgtttgc gtgttgctgt
     2281 tacgaatggg gagattattc aaaaacaaac aataaaagac actggtgcaa ctgctgtctt
     2341 cgaagtgaag ggtggcatcc aagctgtttt tggagggaaa gctgacttat taagtcaaga
     2401 aatcaatcaa atattaggaa aagataatta ggaggttttt aatatgtttg aaattttcaa
     2461 aaagaaaaaa caagaaactt tttatgcacc ttgttccgga aaaatcattt ccatcacaga
     2521 agtaaatgat cctgtctttt cacaaaaatt actaggtgat ggttttgccg tcatacctga
     2581 tggttcaaaa atttatgctc cattggctgg tcgagtaaca aatatatttc ctactaaaca
     2641 tgctattaat ataaaaagca actcaggcat tgattatttg attcatattg gaattgatac
     2701 agttgaatta caaggagagc ctttttcgat ttgtgttcaa gaaaatgatg aggttactcc
     2761 tgaaacctcg ttggttgatg tggattttga caaaataata aaatctggta aagatacttc
     2821 tgttatagtt gtttttccgg agaaaaatca gttcaatgat ttaataatag ataatggtcg
     2881 aattgctcat gggaattcat gtggaaaaat cactt
//
LOCUS       DADVXV010000166         2902 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.173, whole genome shotgun sequence.
ACCESSION   DADVXV010000166 DADVXV010000000
VERSION     DADVXV010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.173"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..596
                     /locus_tag="KB969_002872"
     CDS             <1..596
                     /locus_tag="KB969_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870776.1"
                     /translation="EITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSI
                     HLLSLLVTYCLQKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRY
                     LEEHLSENFLLEQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENEL
                     TYTEIADILGFHSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            737..2350
                     /locus_tag="KB969_002873"
     CDS             737..2350
                     /locus_tag="KB969_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBB6870777.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT          948 a          506 c          520 g          928 t
ORIGIN      
        1 aagaaataac atctatcatt acttttctga aaaatgaaca gttcaaaatt gattatctaa
       61 aacatagtaa gccagctatt tcctatgatc aggaaatcaa ttcttttttc atactatgcc
      121 aacagatgag cattcatttg ctttccttat tagttactta ttgtctgcaa aaaattcaat
      181 tgtcttcctt accaaggcat tatcaacagg aacttgcttt attgacaata ccttcaaatg
      241 agaaagtcat tccaaaaaaa aagcatattc tttattcaga tgaattagtt gatccaatca
      301 tacgatattt agaagaacat ctttcagaaa attttttgct tgaacaatta gcccaaattt
      361 tttttatcag tccagccagc ttaaaaaaac attttagaaa agtgaatgga aaaagtgtta
      421 ttagctattt taaagaacta aaaatggaaa aagcaaaacg tctcgtgcta gaaaatgaat
      481 taacctatac agaaattgca gatatattag gatttcattc gatccatcat ttttcttcag
      541 cttttaaaaa atatacaggg ttatcccctt caaagtatta tctatcctta aaatagaaaa
      601 aaatttttag gttttatcca caaattattt ctctatattt tctgtctatt caaaataaac
      661 aataattttc cggcacaatt atttgctgtt ttttaccata acatagtacg atcaacgtag
      721 aaaaggagat gtttttatga aagttgttgt cattggcggt gtagctggcg gtccttcatt
      781 tgccactcgt ttccgtcgat tgaatgaagc gcacgaaatc attatctatg aacgcggaga
      841 aaatatttct tatgcaagtt gtgctttgcc ttattattta ggaggtgtga tcactgaccg
      901 tgactcgctg atcgaacgta caccagaaat attgaaaaca aaaaacaaca tcgatgtctt
      961 tactaaacac gaagtaacag caatcgatcc ttctactaag cgattaacag ttaaagacct
     1021 atccacaaat gaagaaataa aaacagatta cgataagttg atcatctctt ctggtgctag
     1081 accagattat ccggatattc ccggagtttt tgaagcagaa aacggctttg tcctccgtag
     1141 tgtgacggat gcggatcgaa tcaaatcgtt ccttgaagaa aaaaatccac aacatgtcgt
     1201 cattcttggt gcaggtgtta tgggtctgga attagctgag aatttcaagc atcgcggctt
     1261 agacgtgact ttaatcgatc aattgccaca agtcgctttc ccttatgatc cagaaattgc
     1321 taatttagtt tatgacaaat tgctgaaaga aggattagcc gttcatttag aaacaagagt
     1381 tactgagatc cgtgataaag gtcgagaaat agtattatca gatggctccg tcctttctgc
     1441 tgatatgcta atttttgctg ttggtgtttc tccgaagaat gaagtggtga aagcaaccgg
     1501 catacaatta tcagatacag gtcagatcat tgttgatgac cagttacaaa ccaatctgcc
     1561 ggacatctat gcgattggcg atattatcga aacgactagt gtagtgactg gtcagccgat
     1621 ccaaagtatg ctttccagtg cggccaatcg tcaaggacat atgctggcag atattttaaa
     1681 tggtacgcct atgcgctatc gcggatatat tggtgcaggt gtcgcaaaaa tctttgatca
     1741 tacagcaagt tatgcgggaa tgacagaaca tgaattaaaa gcatcaggca taacaaatta
     1801 taaaactgtt tttatcactc cctttgacca tgcctatttc tatccagaag ctacaagatt
     1861 aaatctaaag ctgatttttg atgcagatag cggtcgtatt ttaggtggac aagcatttgg
     1921 agaaaaaggt gtcgataaac ggatgggaga actttctgta gcaatcaccg gaaacttgac
     1981 agtctttgat ttgcctgatt tggagttgcc ttactctcca ccgtattcta ctacccgtga
     2041 cccgttgaat atagctggtt atgtcgcaat caatcaaatg acgaatatcg tagaaacgat
     2101 caaagcaagt gatatacccg aaaacgattt gaaagaagcg ttctttttag atatacgtga
     2161 acctaataaa gcaccttctg gcagtatctc ggcaacaaaa aatattccaa tgaatgagtt
     2221 acgagatcga atcaatgaaa tcccaaaaga taaaaaagtt tacattactt tcagaagagg
     2281 attgaatact tatacttctg cccgaatctt ggcaggtttg ggtatcaaag cgattttgat
     2341 tgaagaataa aaaaacgacc gcggtgggta gccgcggtct aggagttatt tttacttgag
     2401 gagtaaaaat gaaaaagtat atagggttgt tggttggtat gtatatagaa tagaagataa
     2461 atgtgaagaa attgtgcatt atttcttcac atttattagg ttatagttta agaaagttta
     2521 aacattgcgc aatttaatta ttttagctgt ttcttttcat aaaaaaacat gttgtgactc
     2581 tgagacaaat catagtccat agtgatgtct ctagagtaac tacgcctaat attacgaggc
     2641 atcatattaa tctatcagca ctagtaccta aactagcatc cctttcgaat attttttctt
     2701 atataataaa gtttgctttc actcctctaa tctcaccaaa tcgactggct tgcgttgtgt
     2761 gatactagga actgattggt ttagaacgac ttttctattg taatcatatt tttcgccatc
     2821 ctcgttgtct tctaatcctt caatgaatga tccctaatgt gtgtattaaa taatttaatt
     2881 tttttgttcc tatttattta ac
//
LOCUS       DADVXV010000167         2895 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.174, whole genome shotgun sequence.
ACCESSION   DADVXV010000167 DADVXV010000000
VERSION     DADVXV010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.174"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..323
                     /locus_tag="KB969_002874"
     CDS             <1..323
                     /locus_tag="KB969_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBB6870778.1"
                     /translation="EEWERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIG
                     DSPGDLEAANKNKVFFYPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKN
                     LTNK"
     gene            336..2102
                     /locus_tag="KB969_002875"
     CDS             336..2102
                     /locus_tag="KB969_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBB6870779.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            2125..>2895
                     /locus_tag="KB969_002876"
     CDS             2125..>2895
                     /locus_tag="KB969_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBB6870780.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMK"
BASE COUNT         1062 a          346 c          583 g          904 t
ORIGIN      
        1 aagaagaatg ggaaagacat gaattattat cattagttga tgaactgtgt tgtcaagata
       61 aaggaaaaaa agaagatatt attcgaagtg taattgaaaa tggttgtgat ttggataaga
      121 tattaatgat tggtgattct cctggtgatc tagaagctgc aaataaaaat aaagttttct
      181 tttatcctat tttggtcaat aaagaaaaag aatcatggga aaacttaaga actgatgttt
      241 tatttaaatg tttatcggga gattatgtag atattgaaca aaaatatata gatacttttt
      301 ggaaaaatct tactaataag tagaggagaa agaaaatgac tataaaagta gatttacgaa
      361 aaaaaccata taatttagat gaagatgcta tttcttggat tgaagagacg attgattcta
      421 tgactttgga agaaaaaata ggtcaattgt ttgttaatat gggatctagt cgtgataaaa
      481 attacttgag taatatggtc aatcagtacc atattggagc tgtacgatat aatccaggaa
      541 ctgctgatga ggtatatgat caaaactata tcttacaaac agaaagtaaa attcctctat
      601 taattgctgc taatacggaa gcaggtggta acggagcttg tacagatggt actgaagttg
      661 gtgtagaagt aaaaattggt gcaacaaatg atgcgaaata tgcttatgaa ttagggagag
      721 tttctgggat tgaagcatcg gctattggat gtaactggag ttttgctcct attgtagata
      781 ttaatagaaa ttggagaaat cctatcattt ctagtcgatc ttttggacaa aaccctgata
      841 aagttttaga acttagttta gcttatatga aaggtattca ggagagtgga attttgcctg
      901 cagctaaaca tttccctggt gacggtattg acgaacgaga tcagcatcta tcttttagta
      961 ttaatagttt aggtacggaa gaatgggata attcttttgg aaaagtatac tcaggcttaa
     1021 tagaagctgg attaccttca attatggcag gtcatatcca tatgccagct tattcaaaac
     1081 attttaatcc tgatctgaaa gatgaagatt tacttcctgc aactttatca aaagaattaa
     1141 tcactgactt acttagagga aaactcggat ttaatggatt agtagttact gatgctagtc
     1201 atatgttagg aatgactggg gcaatgaaac gatcagaatt attgcccact tctattgcag
     1261 ctggatgtga tctatttcta ttttttaatg atccagatga agactttaat tatatgatgg
     1321 aaggctatcg taaaggaatt atcactgatg atcggttatt agatgcctta aaaagaattt
     1381 tagggttaaa agctaaattg ggattacaca aaaaagcaaa agaacaaatt ttattaccta
     1441 agcaagaagc tctggaaaaa attggtttaa ttgaaaataa atcaattttt aaagaggtgg
     1501 ctgaccaagc aattacatta gttaaagata aacaagatat ttggcctatt gtaccagaaa
     1561 aatataaaag gattttacta gtagatgtac atggggtaaa aggtgggttt ggtgaagtag
     1621 ttgctggaaa tagacctcaa gccattgatt tattgaaaca gattttgtca gcaaaaggat
     1681 ttgaagttga aaaatacatt tcacctgaag aagaattgaa aggattatcg caagaagaaa
     1741 aaattaaaaa tatagctgga atatatgctg ctaagagacc aattaaaaat ttaactaaaa
     1801 aatatgactt gatcattaat atagctaatg ttaatccagg cacagttcaa cgaattgtct
     1861 ggccagcaag taaaggaact ccggatatac cgttttacat tcatgaaatt ccaacaattt
     1921 ttgtatctgt acagtgtccg tttcatttgg ctgatgtacc tcaagtaaag acttatatta
     1981 atacttatga tggaaaacaa gaaactttag aaatattggt ggacaaacta atgggtcttt
     2041 ctgaatttaa gggagtaagt ccaatagatg cttattgtgg tttaaaggat acatttattt
     2101 aatatttaga taggagtggt ttatatgttg tatcccatta tgacagagac gaggcaagta
     2161 attgacttaa gcggtctctg gagatttaaa ttagatacaa atgatgactt acaggaagaa
     2221 cttgctttag aaccaataaa tgaaaaagag agttatccga tttcagttcc ctcttcttat
     2281 aatgatttat ttgaaacaga gaacattaga aatcatgttg gatgggtgtg gtatgaaaaa
     2341 gaagtgactc ttcctaaaag attattagaa gaaagattag ttcttcgttt tggatctgca
     2401 acacatgaag caaaagtttt tttgaatgga aagtttatta ctcaacacaa aggtgggttt
     2461 acaccatttg agtctgaaat taatcggttt gtaaaagacg ggaataatcg aattacagtt
     2521 gctgtaaaca atattattga cgatagtact ttacctgtgg ggattatgaa ggaaacagta
     2581 caggaaaatg gggatataaa aaaggaaaac ttagttaatt ttgatttctt caattatgca
     2641 ggtattcata gacctgttaa gttatataca actccgaaag actatataag tgatattact
     2701 attaatacaa gaataactga tttggatgca agtgtagaat tcaatatcga tacagaatgg
     2761 accggaaaaa tcttaatagc gatatatgac gaagaggctc aacttgtagc tgaagctgaa
     2821 ggaaagaaag gaatgattca gcttaagaat ccaatttttt gggaacctct agacgcttat
     2881 ttatatagta tgaaa
//
LOCUS       DADVXV010000168         2884 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.175, whole genome shotgun sequence.
ACCESSION   DADVXV010000168 DADVXV010000000
VERSION     DADVXV010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.175"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            558..>2884
                     /gene="esp"
                     /locus_tag="KB969_002877"
     CDS             558..>2884
                     /gene="esp"
                     /locus_tag="KB969_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBB6870781.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         1044 a          441 c          565 g          834 t
ORIGIN      
        1 atcaataatt taatgaggct gtgacaaatg tcattttttg tttcgctaaa aacgagtgaa
       61 aaaatgttga taactccaat cattcgttta agattctagg aatcattcag aaatgctgtg
      121 aaaccgatac tttataatta taaagaaggt gatttcaaat tccgaagaag gaatttgaag
      181 tcaccttttt acttatgtca cagtctcatt cagtaatgcg ggataaggct ccttattccg
      241 ttatttgaat actctgaagt ttaatctaag aaagggtaat attttgaaaa catgcttcat
      301 cgcatagaaa tgaacttaat ttcagaaaga atacatacat atctttttat atgttttcag
      361 ctgctgaatg gttaaaaagc acaaatatcc gaaaaaaaca tgaagaaatg tacttttttt
      421 gttgtaatgt tcatgaaatt ctctaagtaa attagttaac ataaggttag taagattcct
      481 attctgtgaa taatacgtat cagatttatc ttttattctt actaggaaag taattattaa
      541 gggagttgat ttgaataatg gttagcaaga ataataagag agtatttcta gaaaaaacaa
      601 agaaacgagt attgaagtac agtatcaaaa aattaagtgt tggggttgca tctgttttga
      661 ttggtgttgg tcttgtcttg ggaacaactg aactagttaa agcacaagat gaaatttctc
      721 caagcagccc acttgaaaca gcgataagct ccgtacaagt aggtgacaaa gtagcttcgg
      781 ggaatacttt tcaggagaat cctggttata cgaaaaatta taacttttcg gatttacaat
      841 ttagtcctca agaactaact ggagacacac taaaaggcaa tacaattgga tttgaagttt
      901 acggaaaaca taatattgca gcatcaacta aaaactggga aatccgtctt caattagatg
      961 aacgattagc taaatatgta gaaaaaattc aggtcgatcc aaagaaagga attggatctt
     1021 ctagacggac ctttgtaaga attaatgatt cgctgggtag acctacaaat atttggaagg
     1081 tcaattatat tcgtgcaagt gatggattat ttgctggggc agaaacaacc gatacgcaaa
     1141 ccgctcctaa tggggtaatt acgtttgaaa agagcctaga tgaaattttt aaagagatag
     1201 gcatagacaa tctcaagacc gatcgtttaa tgtatcgaat ctacttggta agtcatcaag
     1261 acgatgataa aattgtaccg ggtattgata gtacgggcta ctttttaaca gattcagatg
     1321 atttctataa tagcttagat gtatctgaaa ataatcctga ccagtttaaa catggatcag
     1381 taagtgcaaa atatgagaaa cctaatactc aaacaaaaga tggttcagga tccacaggtg
     1441 ctaatggagc tataatctta gatcataagt taacgaaaaa ttataatttc tcatattcat
     1501 cttccgcaaa gggcacgcct tggtatgcta attacaaaat tgatgaacga ttagttccat
     1561 atgtagcggg tatacagatg cacatggttc aggctgacaa agtaacatat gatgtttcgt
     1621 ttgaatccgg aacaaaagta gctgatttag caatcgagcg acgggaaggt catgaaaatt
     1681 atggcatagg ttcaataact aataatgatt taactaaact tatcgatttt gctaatgcaa
     1741 gtccacgtcc agtcgttatt cgatatgttt tacaattgac taagccatta gatgaaatct
     1801 tagaagatat gaaagcaaca gcacaagttg aagaaaataa accatttggt gaagatttca
     1861 tctttgattc ttggttgtcg gatacgaata aaaaattaat ccagaacact tatggaacag
     1921 gttattatta tttgcaagat attgatggtg atggaaaccc tgacgataaa gaagagagcg
     1981 gagacacgaa tccatatatc gggaaacctg aattagaaga agtatatgat gttgacacaa
     2041 cagttaaggg gaaagtattc atccacgagt tagcgggaac aggtcacaaa gcccaacttg
     2101 ttgataaaga aggtactgta ttagcagaaa aaactatcgc tccaaatgaa aaagatgggg
     2161 ctccaatttc agatactgta gaatttgaat ttacgggtgt agattcaagt aaattaatcg
     2221 cgaaagatga attaaaaatc caaatcgttt ctccaggttt tgataaacca gaagaaggtt
     2281 caaccgttat taaggaatca ccaaaagcgg ttgataaaca aaccgtggta gttggattta
     2341 aaccagatgc taaagaatca attcggaata ataaaaactt acctgaagat gcagagtatt
     2401 catggaaaac agagcctgat acttctaacg ttactgatag tacgaaaggt attgtaactg
     2461 ttaagatcgg aaatcgaact ttcgacgtgg atgtagagtt tgctgtaaaa gcttctcaag
     2521 ctatggaaaa tgatgcaaca tacgtaccta taacaacaac tccagaaacg acagttcaaa
     2581 gtggaaaacc tacatttgat aaaccagatg ttcctttagc taaagatgcc ttttcaattt
     2641 cagatgtcta taataagtac ttcggtaatg caagtgttga tgcaaacact ggtattgtta
     2701 cattcactcc agctaaaggt gtaggagaat cggagccgat tactggaaca attcctatta
     2761 aaattgttta ccaagatggt tctgtaggca cgaccgattt agcagtaact gtaagtaaag
     2821 atatttatga aaatccagga gaaaacattc ctgcaggcta ccacaaagta accttcaccg
     2881 cagg
//
LOCUS       DADVXV010000169         2866 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.176, whole genome shotgun sequence.
ACCESSION   DADVXV010000169 DADVXV010000000
VERSION     DADVXV010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.176"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            207..1607
                     /locus_tag="KB969_002878"
     CDS             207..1607
                     /locus_tag="KB969_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870782.1"
                     /translation="MWLLNICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIY
                     YRSAIAEAIALTIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIA
                     CMIIVRLFLSKQIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTD
                     LQLEALSISDSIIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTW
                     VCVTNLFPWFLFQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGA
                     TVVFLLVTSIAAKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERP
                     HLEKHEVKVGESWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVND
                     SYKKHGLVNVDVNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKD
                     SRYVTKKEINKKNENK"
     gene            1594..>2866
                     /locus_tag="KB969_002879"
     CDS             1594..>2866
                     /locus_tag="KB969_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870783.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDY"
BASE COUNT          959 a          424 c          473 g         1010 t
ORIGIN      
        1 ctcaagaaat ttatacaaca ggtgatttat cttttcatct ttcacgaatc aaagggttat
       61 cttctatttt tgaagggcca atcaactata caacatttaa caattatgga gatggactga
      121 actattttta tccttttctt acaataattc ctgcagtcgt tttttatgga atttcaaata
      181 acttaatatt aagttatgtt ctatatattt ggttattaaa tatttgtacg attctgatta
      241 gtttttatta tggagaaaag ttttttaaaa agatagatgc tgctttttta tttagttgtt
      301 tatatacttt tgcaacttat cgaacagttg atatctatta tcgatccgca attgcagaag
      361 caatcgctct tacgattatc ccagctgttt tatattatgc ttatggattg atattcaata
      421 gagaaaaaaa agtcatcgct ttatctgtca gtataagtct acttgtgtat actcatgtct
      481 taactacact attgtgtagt gcattgattg cttgtatgat tatagttcgt ttgtttttaa
      541 gcaagcaaat aaaaaacgat ataaaatttg tggtcgtgaa tttagtaaag gctgtttttt
      601 tgacttgtgc attaactagc tatttttggt atcctatgtt gcagcagatg aattatcaag
      661 aaatacacag tcccttcaaa acagatttgc agctagaagc actttctatt tcagatagta
      721 tcattcaagc gttaaataac gatattacaa catacactat ggggttatta ggattggttg
      781 cgttgatttt tcctttattc atactgaaag aaatggagaa aaaagaaaaa atcatctatg
      841 ttggcgtagt ttctacatgg gtatgcgtaa ctaatttatt tccatggttt ttgtttcaaa
      901 aaacaccgat aagcttactc cagtttcctt ggcgtatctt aggtatccaa atcttttttt
      961 cttcaatgat cataacgctt gtttttatga aaaagactat gaataaaaaa tattcatggt
     1021 taatcattgg cgctactgtg gtgtttctac tcgtcacgtc tatagcagca aaagaaaatt
     1081 acgcaaaagt tatccaatca aaacacggtc atattgttat caatgaagaa acactcccac
     1141 gttatacaac atcagatatg ggaggattat acgattacgc cccaacagaa gcgataaaag
     1201 aaaggcctca cttagaaaaa catgaagtaa aagtaggaga atcgtgggaa aaagggaagt
     1261 ataaagctgc agataataac attacttaca cagtggcaag caacaaaaag caaaaagtga
     1321 cagtaccagt atatgcttat ttaggtacac aggtaaaagt aaacggtaaa gtcgtaaatg
     1381 actcttataa aaaacatggc ttagtgaatg tggatgtaaa tgctggagaa aataagatag
     1441 aaattacaac aaaatatact ccaactgctc tcatggcttt atggatcagt attctgactt
     1501 attgtttagt ggtgtattca agttttaaac gatttgcacc taataagttg aaagattctc
     1561 gatatgtgac taaaaaggag ataaacaaga agaatgaaaa taaataaaaa agtagtaata
     1621 ttgagtggat taattatagt tagtagtata tattctttca tctttttcaa aaatacacag
     1681 agtatttata ccactggaga tctttctttt cacttatctc gaatcaaggg gttatcgact
     1741 atttttacca gtccgattaa ttatgagaca ttcaattata ctggatatgg tgtaaattat
     1801 ttttatccct ttctgacttt ttttccagct gtaatgttat attggatgac aaaaaatttg
     1861 attgtaagct atattattta cgtttggtta ttgaacttgt gtacaacact cgtagcttat
     1921 cattatggcg agcggttttt aaaacaaaaa aaagcggcat ttttatttag ttgtctctat
     1981 attttctctg cttatcggac agtagacatc tactatcgtt ccgcaattgc cgaagctatc
     2041 gcaataacac ttgttatccc tgtattattt tatgcttatc aaatcatctc tggaaaagaa
     2101 gaaaagtatc cgtctgtaaa gctagcattg agtatgagtt tgctagtgta cagccatgta
     2161 ctatcaacat taatgagtac agcattaatt atcattttta tttttattcg tttggtttct
     2221 aaaggtttca agaatgcaga ttttattgct atatttaaaa aattatttag tgcggcagga
     2281 atgacattgg ttctgacgag tgctttttgg tatccgatgt ttgaacaaat gctctaccaa
     2341 aaaatcaaca aacctagcgt gacaaattta tatgctcatg catctaatgt gttcgatagt
     2401 ctgactgaag ctatgaacaa cgacttaact acttactcaa tgggactagt tggtctgtta
     2461 tctttatgta ttcccctgat tttatttaaa aaattaacaa acatagaaaa aaagatttat
     2521 tatggtacgt gtttgacttg gctagctaca actagtttgg tgccatggta tcttctgcaa
     2581 aatacgccag ccaaattgtt acaatttcct tggcggatct taagcttgca aataatattc
     2641 tcttctctga tattaacgat gatatttttc aaaaatagaa gatacaataa gacaagagaa
     2701 ctattttatt tatttatgac tgttttgtta ttaatcactt taactgtttc tagtaaaaaa
     2761 aatttcaatc aaaaaataat ttctcagccg ggacatattg ttgtaaacaa agaaacagta
     2821 gaggcgtata ccactaaagg aatggattat tttttatatg attatt
//
LOCUS       DADVXV010000170         2847 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.177, whole genome shotgun sequence.
ACCESSION   DADVXV010000170 DADVXV010000000
VERSION     DADVXV010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.177"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..396
                     /locus_tag="KB969_002880"
     CDS             <1..396
                     /locus_tag="KB969_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBB6870784.1"
                     /translation="VCLNFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKKML
                     EKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKNLR
                     YRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            368..1084
                     /locus_tag="KB969_002881"
     CDS             368..1084
                     /locus_tag="KB969_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBB6870785.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            1081..2199
                     /locus_tag="KB969_002882"
     CDS             1081..2199
                     /locus_tag="KB969_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBB6870786.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            2189..2809
                     /locus_tag="KB969_002883"
     CDS             2189..2809
                     /locus_tag="KB969_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBB6870787.1"
                     /translation="MMRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLG
                     SPIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELP
                     ELWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKF
                     DLDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
BASE COUNT         1084 a          358 c          554 g          851 t
ORIGIN      
        1 gtttgcttaa actttgattc gacaccagta agtattgttc ctagaaaaag aatagcaact
       61 agaggtgggg aaatactgaa gggtcagatt attaaagata gagaactaat tgagactacg
      121 aaaaagatgt tggaaaaatt aaatgcaatc ggacatatta ctattcaatg tataaaaaac
      181 gaaaagggaa tattttattt agaaataaat gcaagatacg gtggaggagc ccccattagc
      241 attaaatcag gagctaattc ccctgaatat attataaaga tgatagattc aaaaaaaaat
      301 ttgagataca gagaaaatta tttagataaa atgatagcac tgagatatga tcaagcgatt
      361 tatttagatg aaaaaggaaa tgtatataat gattaaagcg gtgatctttg atttagatga
      421 cactcttgtg tctgaatatg attatgtaaa aagtggatac aaatgtgtag ctagaagatt
      481 agcagtgcaa aaaattttcc cggctacttt tgacgaaata tatagagtcc ttttagatct
      541 ttttgctgaa gatagtaaaa atgtatttaa tcgtctatat gactattttg aaattcctta
      601 tagtaaaaaa gaaattaaag aactggtaaa tgtatatcga gaacacaaac cagacataaa
      661 ttttttagaa aatgcagata ctttattaac ggaattaaga agtagaggat acaagctggg
      721 gattattaca gatgggtatg ctataaccca acgaaacaaa ttggatgctt tgaaagtaga
      781 ctatttggta gattatattt gtattactga cgaattaggc cgtgaattgt ggaaaccaca
      841 ccctatctca tatcttttat tgttagaaaa gtttaattta aaggcacaag agtgtatata
      901 tattggcgat aatgagttga aagattttat aactgccaaa tcaataggaa tgcaaacaat
      961 taaaatagaa agagtaaatg gtatttacag agaaagcagt ttgaagttca aaagatttta
     1021 ccaagctgat aaaaaaatac gttcgttatg ggagataaaa aattttttgg gagtgatttc
     1081 atgaaaagta aaagaattct attagcttct ccacatatga gtgaagaagg atatgaaaaa
     1141 gagtatgtaa aagaagcatt tgatacaaat tgggttgctc ctttaggtgc gaatgtgaat
     1201 ggatttgaga aagaattagc agaatacgtg ggagctagtc atgctgccgc attatcttct
     1261 ggaacagcag ctatacattt agctttgaaa gcggctgggg tcggtaaaga tgacatagtg
     1321 atttgtcagt ccttgacgtt ctcagctact gctaatccaa ttctctatca aggagctata
     1381 cctgtatttg ttgatagtga ttacgaaact tggaatatga aacctgaaca tttgcgaaca
     1441 gcactagaaa aatatcctaa cacaaaggct gtattagtag tacatttgta cggtttatca
     1501 gctaatttag acgaaattac taaaatatgc aaagaatacg atgttactct aattgaagat
     1561 gctgcagaat cattaggaac aacatataaa ggaaaatata ctggtacatt tggcgactat
     1621 ggaatttatt cttttaatgg aaataagata atcacaactt caggtggcgg aatgcttgta
     1681 tccaatgaca aagaaaaggt ggaaaaagtg agattttggg ctacgcaatc tcgtgagaag
     1741 gcacgccatt atcaacacaa tgaaattggc tataattatc gaatgagcaa tatcgttgct
     1801 ggtatcggtc gaggacaatt gaaagtatta aatgaaagaa ttgagaaaaa acgatatatt
     1861 catagttttt ataaaaaaga attgtctaaa ttgtcaaata tacaattcat gccagaaaat
     1921 aattggaatg aaccgaatta ttggttaagt gtcataacaa taaagggaat aaatgcgaat
     1981 catcttattg atgagttaga caaaaataat atagaagccc gcccagtatg gaaacctatg
     2041 catttacaac ctgtttttaa aaattatgat tatattggcg atgatgtagc agaaacttta
     2101 tttgacttag gagtatgttt accatcagat acaaagatga cagatgaaga tttaaaatat
     2161 gtagtatcta cgattaaaag agtgatcaat gatgcgtaaa aaaactttct atcagctttt
     2221 tgggaaaaga attttagata tcctattgtc aggaattgct ctcatcgttt tatcgccgat
     2281 aatcttaatt gtaggttttt tagtaagaat taaacttggt tctccaatta tcttcaaaca
     2341 agaacgacca ggaaaaagtg aaaaaatttt ttccatgtat aaatttcgta caatgactga
     2401 cgaaagagac cacaatggag aatatttacc tgatgaaatt cgactaacta aatttgggaa
     2461 aatgcttaga gcaacaagtc tggatgagct acccgaactt tggaatattt tgaaaggtga
     2521 tatgtcgatc gtaggacctc gtccattatt agtggagtat ttgccactat atagtgagaa
     2581 gcaacggaaa agacacaacg taagaccagg attaactgga ctggctcagg tcaatggaag
     2641 aaatgctatt agttgggaag aaaagtttga tttagatgtt tattatgttg ataaaattag
     2701 tttctttaat gatcttatta ttataattca gacatgtaaa aaagtaatca agaaagagaa
     2761 tattaataca atcaataaca atatcccaga aaaatttaaa gggagttaaa tacagcagct
     2821 taatgcaagt tttgtgactt gcattat
//
LOCUS       DADVXV010000171         2769 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.179, whole genome shotgun sequence.
ACCESSION   DADVXV010000171 DADVXV010000000
VERSION     DADVXV010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.179"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(76..1875)
                     /locus_tag="KB969_002884"
     CDS             complement(76..1875)
                     /locus_tag="KB969_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBB6870788.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(1999..2595)
                     /locus_tag="KB969_002885"
     CDS             complement(1999..2595)
                     /locus_tag="KB969_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBB6870789.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT          977 a          522 c          480 g          790 t
ORIGIN      
        1 aaaaacgcat atacctgcgg tggcaggtta tgcgtttttt gttgtataaa gacttttttc
       61 attaacgatt tttgattagc cgactcccaa aacaaaattt agcagtttat ctgaataagt
      121 gatttcttca tctgtttgtt tcacactttc atttagtagt cccatctcat cggttatgat
      181 accatccaca ccataaaaca tcatgcgact catagcatct gaatcgttga ttgtccatac
      241 atatacttct tttccgtctt ggtgggcaga attaatgaag ttacggttga tcgtactata
      301 ttccattgtc agaaaatcag caggcgtcac agggggccca acaatattga aaggtaagat
      361 gtagcccaca taaaagtttg gttctgcttc ttttaaatct gaaacggttt ggtacgtcaa
      421 actttgcaaa atatgatggt tctctaagat aactttgcgg tatttatgga caaatcgttc
      481 gacaaggtca tccgaatctt ttttagaggt cttgatctca ataagtaatt tttggtttag
      541 cttatgtgct ttttccaaat aagaatcaaa agaacaaaca ggggcttgca ctccgttttc
      601 agtaactgta agatttgtca attctttcaa tgtaagatcc tgtggtgttc catttacccc
      661 tgttaagtga cgaagatttg catcatgcat cactacgaaa tgaccatctt ttgtttcctg
      721 aacatccatc tctacataat caggatgata gtctctgctt gttttttcaa gtgcttctaa
      781 agtattttgc gccccatttt gggtactcac acctctgtga gagacagtca ctggttttgt
      841 ctgaacagct gaagtcagat aatccatatt gtaaagacag acgccaatac cgaaaaaaac
      901 tgcaaaaaga gtcaaaccag tgtttttcag cgcagagaaa cgcaagttgg gggcttgtgg
      961 gataaaccac ttagggatct caggcaagaa gccttcgtca tccatgaaat caacaatgat
     1021 ataaaaaatc cctacggtag acatcacgat attgaataat aaaatccctt gtaaaagcgt
     1081 catagcaaac acagcgctga tcaatgcata gtctgggaaa aattgttcaa ccatactttg
     1141 tgccaaaata acaacgatat atcctaaaga agaaaggagt aaaatcgtac cgccaatcac
     1201 aataaattgg cccgtgatgg ccaaaagacg cgatttggtc aatgaccagc tttcccgaat
     1261 ggctgctcga aaaggacgat ctcgtagaat catttccggt aaagcaaaaa tcagtcgaat
     1321 cccaatatag ccaaggaaaa tataaacgag taaaaaggaa ctgacgatga tccaacgatt
     1381 agcaaaaata aaatccataa tgaaagcggg gatttttatt tttgacagta gatcagaatt
     1441 aaaacttaat ccgctgatcg gtagaatcaa taaaaaataa gcaaggaaaa acaaaaaagt
     1501 aatgggtctc actttcttca gctgaagtat cgtcaagtgt aagagttgct tcaaagagat
     1561 tggttctttc tttttaataa aaaaaacact catcaaaaga aaagtaaatt cgaaataaac
     1621 taacagtaaa atcgtcatca aaactacgat taacgagagt agaaccccag gatgttgaga
     1681 aaaaattgaa ggaatattgt cataagacaa atagtcaatt gcccctcggt gtaaaataaa
     1741 acgggtcgta ctgctcaata agggtaaaca aataaataaa ataaagccat gcatcagcaa
     1801 gacatcacgg aaataagctt gtgttccttt taaaaagtcc caagcattac ctaagctacg
     1861 tttcaaataa ttcatcctat cacctgctct tcacattgta gcgcaaatct aatgaaaaag
     1921 gaaagggtgc agtgtgtttt gcagaccctt tcccagattt aacattgtca atcaatgact
     1981 aattttacaa aataaatatt atccaagaag accacttaga tattgacctc cataaatcaa
     2041 ggccatacta tataagaaaa tcgacagtgg tttagcaatc aaaatgatta gtgtatatcg
     2101 tttcactgac atgtttgtca atccagccat caaacataac gcatcgtcag gagcaactgg
     2161 aagaaaaata gctagagcaa acagcttctc aaaacggttt tgattatcca gccagccaat
     2221 atatttgtta tatgtcttat cgctaatcat ggaaagtatg aatggctttc cataacgacg
     2281 ccctagcaga aaaatgataa tcgaaccaat gcagattcca atatagttat agataaatcc
     2341 agcataaggg ccaaatatca ggacaccagc tgcagtactg atccctccag gaatgattgg
     2401 aataactact tgcaggattt ggatgaagac aaaaataatc ggtcctaaaa tgatggaatc
     2461 acctactaat cctcttaacg cattcaaatc tttgaaaaca cctaaattaa taaaataaat
     2521 cgtcagcgcg attgataggc ctaatccgat aatggatatg aaatttatca gttttcgaga
     2581 ggcagcaata ttcattattc atcaactcct tagaggttct ttgttaacta tactttacta
     2641 gaaaagcaac taactgcgcc attttttgat atgacagaaa acaaacaatt ttgtaagttc
     2701 atcataagta taaaagattg atctcaaaaa aacatccaac taaagactta tttaataact
     2761 tgttttttt
//
LOCUS       DADVXV010000172         2721 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.180, whole genome shotgun sequence.
ACCESSION   DADVXV010000172 DADVXV010000000
VERSION     DADVXV010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.180"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(266..631)
                     /locus_tag="KB969_002886"
     CDS             complement(266..631)
                     /locus_tag="KB969_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870790.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            839..1321
                     /locus_tag="KB969_002887"
     CDS             839..1321
                     /locus_tag="KB969_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870791.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1518..2408
                     /locus_tag="KB969_002888"
     CDS             1518..2408
                     /locus_tag="KB969_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBB6870792.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT          924 a          439 c          533 g          825 t
ORIGIN      
        1 aactattttt tatggaggaa ttgttttaat tagtttactt tcttcaacac tttattcttt
       61 gaatattata gatgtttcca cctcaaattc aatatctatt attggaatca ttattgctgc
      121 aattattaca caactgtttt tagtgtttgg agagaagaaa agaagtaaaa aatagaaaaa
      181 ctagtgatag ttttggtgat ataagaaaaa catatatgta taaaaagaag aaagtagctt
      241 ctctttgtac atatatggtt tgtttttatg gatgccgagc ttttttataa gataaggcta
      301 ccgcccataa cgacccaagg atttgtggaa ctaagtaaat acctgcaaga agcaagatca
      361 gctgggtcgg ttttaaagga tgatagaagt aacgccattc agtaaaattg gcgcaaaata
      421 aataggaagt gacagtagat ataatattgg caatgaataa agatataata cgcctgttcc
      481 tttgaaaata atatccagca aaaagagata aaaatatcaa tgtgatgaac ccgcttacgg
      541 aatgataacg aaaatcaagc agtaaggcga aatgcacata aggaacaaaa gataaaagca
      601 acggaaggtt tttccagcaa gtttttatca tctttcatca ccacctaaca agtgttatta
      661 ttttgttagt tttattgtaa attgaatcct gcaataatca attacttttt cattatttct
      721 agattaaatg aataaactct catgccatta tctctaaaaa aaaagttttt ccccctaatt
      781 tttttagata gaaaattgta tagtatgatg agagaaaaag tagtttgggg gaacgttaat
      841 gagaagaaaa gcagtaatcg atcggcttta tttatttttt tggttttttc ctatcgtttt
      901 gctacctttt acatgggtaa atgctgttgt acaaggtgcg gagatattag gcctgatcca
      961 aggaagcgga tttgtggttt ctaggaattt tccagctttg attgttttct atttagtgat
     1021 aagtgtaggt ctcttattac caaaatctct gatcaatcac tacaattggc agctgcttta
     1081 cttttcttgc ttattagtat ttacatctac gttttctttg ctgcctcgct tgattatcgg
     1141 ccctaatggt ttgagcgaga gtggattgaa ggatttagct tattcctcca tgtatttctt
     1201 gacgatcaaa ccatggttct atttagtaat tgcctcattt attcttgcaa cattttttta
     1261 cttctggaca gaaatcagga taaaaagtga acgatctgta tctataaaaa ataactattg
     1321 atggtggatc atcagtaaaa aaacatatga gctgcgtaaa atgcatgttt ctcatatgct
     1381 ttttttatta ttatgtaaag aatgcgaaaa acgtttacat gatttttaca taacttaact
     1441 atatttttac agcaaccata cgagggattt acagtcgact gataaacttt agttgtaaat
     1501 aagaaaggag caataaaatg aaaaaagtat tgtttactct aggtatgatg ggaattcttt
     1561 tagccggatg cggctcagga tcaggaaata cagatggctc tgccacacaa aataattcaa
     1621 gtgactcaaa tgaacaagta aaaatcgttg cggtaggttc gacagcatta cagccgttag
     1681 tcgatgcagc acaagaaagc tttgtacaag aaaatccaaa ttatcaaatc tctgtacaag
     1741 gaggaggaag cggaactggt ttgagccaag tcgaagctgg agcagttact atcggaaact
     1801 ctgatgtatt tgcagaagaa agagacggag ttgatgcttc aaaattagtg gatcataaag
     1861 tagcagtggt cgggatggca ccaatcgtca ataaagatac agatgtcaaa gatatcacca
     1921 aacaggaatt gattgatatc tttacaggaa aaatcactaa ctggaaggaa gttggcggga
     1981 aagatcaaaa aatcaacgtc gtgaaccgtg caaacggcag cggtacccgc gcgacattcg
     2041 aaaaatgggg actggatggt gctacccctg tgcagtccca agaacaagat tcatcaggaa
     2101 cagttcggca gctggtaagt caaacaccag gagcaatcag ctatttagct ttctcatatc
     2161 tcgatgattc cacacaagca ctaagtatcg acggtgtaga accaaaagaa gagaatgtag
     2221 cagataacag ctggggaatc tggtcatatg aacatatgta cacgaacgga aaaccttccc
     2281 ctgaagtcca aaaattctta gactacatga tgacagaaga aatccaagaa ggacctgtca
     2341 aagaattggg ctatttacca atcacaatga tggaagtaga acgtgatcac gaaggaaata
     2401 tcaaataact agcagataaa catgccacgg tagtcgttac tattaaggaa aaatcaacta
     2461 tgtttcccca catatacatt tttcctttaa ttgtgaaaaa tagttcctca tattttgccg
     2521 ttttttgagc taataccgag ggtcagctga ttgaacaccg tttattcgaa aaaaagagct
     2581 acgacataga actgtcgtaa ctttttttgg ctcttcgtca aatcgtgttg gtgaagacaa
     2641 atttgaataa aacttagacc gatatgcggc gcgttctgtg cgccgcatat ttttttagtt
     2701 ttcaaagatc agaccttgtt g
//
LOCUS       DADVXV010000173         2613 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.181, whole genome shotgun sequence.
ACCESSION   DADVXV010000173 DADVXV010000000
VERSION     DADVXV010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.181"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            316..570
                     /locus_tag="KB969_002889"
     CDS             316..570
                     /locus_tag="KB969_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6870793.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="KB969_002890"
     CDS             571..888
                     /locus_tag="KB969_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBB6870794.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="KB969_002891"
     CDS             1447..2382
                     /locus_tag="KB969_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870795.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
     gene            2476..>2613
                     /locus_tag="KB969_002892"
     CDS             2476..>2613
                     /locus_tag="KB969_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBB6870796.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT          958 a          375 c          482 g          798 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagagaaaaa
     2401 tgtctaaaca tgttggtaaa tcaacaaaaa aacgcatata gtagtctcaa aactcccaag
     2461 aaatgaggac tacatatgcg ttcatcaaaa tatactgaac attatacaga tacttttata
     2521 acattcaagg aaattatgag aactgtttct aacatatacc acaattgtgt accagataag
     2581 attaaaaacc gaagaaatac tgatcaactg aag
//
LOCUS       DADVXV010000174         2566 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.182, whole genome shotgun sequence.
ACCESSION   DADVXV010000174 DADVXV010000000
VERSION     DADVXV010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.182"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..78
                     /locus_tag="KB969_002893"
     CDS             <1..78
                     /locus_tag="KB969_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBB6870797.1"
                     /translation="LELFFAVFLFLGKNSLKQTKKKELV"
     gene            complement(108..617)
                     /locus_tag="KB969_002894"
     CDS             complement(108..617)
                     /locus_tag="KB969_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBB6870798.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(729..1727)
                     /locus_tag="KB969_002895"
     CDS             complement(729..1727)
                     /locus_tag="KB969_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBB6870799.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1928..2512
                     /locus_tag="KB969_002896"
     CDS             1928..2512
                     /locus_tag="KB969_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBB6870800.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
BASE COUNT          801 a          475 c          483 g          807 t
ORIGIN      
        1 ttagaattat tttttgctgt ttttcttttc ttaggaaaaa atagcttgaa acaaacaaaa
       61 aagaaagaac tcgtctaaat agacgttttc tttctttttt tgttgaatta ttgagtaagg
      121 cgacttcttt tttctggttc tttgtgtgct aatcgactgg cagcagcagc ggcgatcgct
      181 ccgacgatat catctaagaa ggtatggaca tgaacgccat cgtggctgtt tagttctttt
      241 aaaataccag gtttcacctt gtcgatataa ccataattcg taaagccgat cgtaccgtaa
      301 acattcacga ttgacaaggc taggatctca tcgataccgt aaaggccttc gtcatcttcg
      361 ataatatgtt gcaacggact catcaatttt ttcttttctg ctaatatatc taattggatt
      421 ccagtgataa tggcgttatg tacttcacgc tttgttagca cgctgttgac actttcagta
      481 caatccgcca aagtcaaatc agaaatatag tctttttgta aaaacatgac aagttgtgcg
      541 atatcttcta cagttacgcc acgttccttc aatagttctc ttgccttttc ttctaaagtc
      601 tcagttttga cgaccatatt attgctcccc ctttattttt tctttctcta tttcatgtta
      661 acggaacatg aaaaaaatgc aagaaactgc tttcgggttt aacttgaaat gcaaagagat
      721 ataaaaaatc aactaggacg aagattttta tcgtataagc ttgtgctgtg accaggctga
      781 gttcgttcct ttggattaat atagtgtaaa gcgttgttca ctgcagtagg tgcttcaccg
      841 agcccagtag caatcagttt cacttttcct tcataggtac agatgtcacc agctgcataa
      901 acgcctggaa tagaagtaga catatctgat tttacagtaa tggcatttct ggtactatca
      961 agtccccaag aagaaagatg ttctaaatta gaagagaatc cataattgac gatcagagaa
     1021 tcaatcatca aatcaatcgt ctcgtcactt ttcacttttt ttaaccggat atctgtcagt
     1081 tccccattat tgcctgataa tccatcgatg agatagggag taagcaagtt gacagatgaa
     1141 gatttcaagc gtgatacact atgttcgtgc gcacgaaatt ccgggcgacg atgaatcaag
     1201 taaacttcgc ttgcaatagg ctctaacatc aacgtccaat cgatagcaga atcaccacct
     1261 ccagcaatag cgactttttt tccagcatac ttcatcaaat cattcacgaa ataatccaat
     1321 ccgtggtttt caaatgattc agcattatct aaattcaatt ttcttggctg gaatgaacca
     1381 tttcctaaag ctaaaatgac tgctttggaa taatggatgc ctttatttgt agtaatctcg
     1441 ataacttcgt cttcacgagt aagcgagaga acttcttctt ttaaatggaa tgtatggtta
     1501 aaagtagtta attgtttttc taattgatcg attaattcac ttgcttttat tgctggatac
     1561 ccaggaatat cgtaaatata tttttcggga tacaaagttg ctaattgacc accaagttga
     1621 ggtagactgt caatgatttt tgttttagct tggcgcattc ctgcgtaaaa agcggcaaac
     1681 atccctacag gacctgcacc gatgattgta atgtcataga tttccataaa aattcctccc
     1741 ttttcacact atatcagaat ttaattgaga atgcttctca aaaatgtttg aattcgaaat
     1801 cgaaacggta agttatagaa tgtatctagt gatgaaaaat aaaagaaaac aaatctagta
     1861 tttttacgag aggttaggta ttatgttatt attattatga agtatgcaaa tattaggagg
     1921 aaacaatatg gcattcccac aactagattt aaaaagtgaa aaaggaccaa aagctgttat
     1981 caaaacaaac cgtggtgaca ttactgttca attattccct gaactagcac cgaagacggt
     2041 tcaaaatttc attgaacttt ccaaaaaagg ttattatgat ggcgtgattt ttcaccgcgt
     2101 tattcctgat ttcatgatcc aaggcggcga tccaactgga acaggaatgg gtggcgaaag
     2161 tatttatggc gaaagttttg aagatgaatt cagtcgtgaa ctgttcaacc ttcgcggagc
     2221 tttatctatg gcaaattcag gtccaaacac aaacggaagc caattcttta ttgtaaataa
     2281 cacaaatgtg ccagctaata tgcttggaca actagaaggt gctggattcc catcagaaat
     2341 cattgaagcg tataaaggtg gcggaactcc ttggctagat ttccgacata cagtctttgg
     2401 acatgtacta gaagggatgg acacagtaga tgaaatcgca aatgtacaac gtggtccaca
     2461 agaccgacct gtacatgatg tagtgattga aacaattgaa atttcagaat agtttggtat
     2521 ggtacggagt aattatgaaa aaggacgaaa cctagtaagg tctcgt
//
LOCUS       DADVXV010000175         2429 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.183, whole genome shotgun sequence.
ACCESSION   DADVXV010000175 DADVXV010000000
VERSION     DADVXV010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.183"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(287..649)
                     /locus_tag="KB969_002897"
     CDS             complement(287..649)
                     /locus_tag="KB969_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870801.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(723..1103)
                     /locus_tag="KB969_002898"
     CDS             complement(723..1103)
                     /locus_tag="KB969_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBB6870802.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1167..2360
                     /locus_tag="KB969_002899"
     CDS             1167..2360
                     /locus_tag="KB969_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBB6870803.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
BASE COUNT          785 a          449 c          391 g          804 t
ORIGIN      
        1 ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg ctgttaaatt
       61 tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga aatgattttt
      121 cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa ataaaatgca
      181 ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac aataaaaaaa
      241 gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag aagaaaggca
      301 ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct tcccaaatat
      361 atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca aacaacggaa
      421 cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg ctaacatcga
      481 tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt ccttcagaaa
      541 gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat tttttagtac
      601 catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa atttccacct
      661 cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa aaaatacact
      721 ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat ccaaataggt
      781 aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa ataccttttt
      841 ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa actgattttt
      901 ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac ttttaacaat
      961 gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag tccttgcgtc
     1021 tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt tccttcaatt
     1081 atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat tatactgtaa
     1141 atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc gaatttgata
     1201 aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct gagacatatc
     1261 aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct cccggtgggg
     1321 tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc actctgtctg
     1381 ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg gagttgacga
     1441 aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca gtacaaactt
     1501 ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca ttttcctcta
     1561 ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa aataatcatt
     1621 tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta aaagcaatga
     1681 ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa ttgaaacagt
     1741 taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc catcaagatt
     1801 taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat ttagatgatc
     1861 tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc aaaaattcaa
     1921 tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta gtgatgaacc
     1981 aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat gagacgggtg
     2041 gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca gttaatcagt
     2101 tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact tacttaatgt
     2161 ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact cttgttcgga
     2221 aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat gggcatatgc
     2281 gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga atcaagtatg
     2341 ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc ttactaggtt
     2401 tcgtcccaga ctgtagacaa agtccattt
//
LOCUS       DADVXV010000176         2427 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.184, whole genome shotgun sequence.
ACCESSION   DADVXV010000176 DADVXV010000000
VERSION     DADVXV010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.184"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(151..2304)
                     /locus_tag="KB969_002900"
     CDS             complement(151..2304)
                     /locus_tag="KB969_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBB6870804.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          626 a          541 c          419 g          841 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aaccaagaag tatttaatat
     2281 ttttttcata aaatctttca tcatttccta tccttccgcc tatttacatt catgcttcat
     2341 tgtacccaaa aacttcttaa taaacaagaa gtatttaata tttttttcat aaaatctttc
     2401 atcatttcct atccttccgc ctattta
//
LOCUS       DADVXV010000177         2400 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.185, whole genome shotgun sequence.
ACCESSION   DADVXV010000177 DADVXV010000000
VERSION     DADVXV010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.185"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            207..2069
                     /locus_tag="KB969_002901"
     CDS             207..2069
                     /locus_tag="KB969_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6870805.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="KB969_002902"
     CDS             2069..>2400
                     /locus_tag="KB969_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBB6870806.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DADVXV010000178         2342 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.186, whole genome shotgun sequence.
ACCESSION   DADVXV010000178 DADVXV010000000
VERSION     DADVXV010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.186"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            100..1059
                     /locus_tag="KB969_002903"
     CDS             100..1059
                     /locus_tag="KB969_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6870807.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSAASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(1312..1461)
                     /locus_tag="KB969_002904"
     CDS             complement(1312..1461)
                     /locus_tag="KB969_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870808.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            1923..2135
                     /locus_tag="KB969_002905"
     CDS             1923..2135
                     /locus_tag="KB969_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870809.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
BASE COUNT          849 a          371 c          404 g          718 t
ORIGIN      
        1 ttattacgcc gattgtaaaa ttaagctaga caactaaaaa agtcatttgt gctacactca
       61 aaatagttcc gaccaaagaa ttataaggag tgagtacaaa tgacctatac ccatcttaca
      121 acggatgaac ttgtaataat agagtcttat ttcaaaatga atcaatctgt tgctaaaact
      181 gcccattgct tgaatcgttc aagacaaacg atccataaag tatatctgtt cttcaagcaa
      241 ggaaaatcag ccttagaata ttatcaacag tataagaaaa acaaatcaaa ctgtggtaga
      301 cgtccgcttg ttttacccga ggaacaatca gaatatattc aaagaaaggt tgttcaagga
      361 tggacacccg atgtgattgt tggtcgtgca gcgtttccta ttagttgttc tgctcgtacc
      421 atttatcgta tgttcaaaaa ggggctattt gattcttctg acttaccgat gaaaggcaag
      481 cgtaaaccga atggacatca agaaagacgt ggaaaacaaa ctttccgccg ctctattcat
      541 gaacgtgaaa aggattatag ccaattctca aatgagtttg gtcaccttga aggtgacact
      601 atcgtaggtc tgaaacataa aagtgctgta attaccttag ttgaacgatt atcaaaagtt
      661 atcatcacat tgaaaccgtg tggtagacaa gcgattgata ttgaaaaaaa attaaatcaa
      721 tggtttgaat ctgtaccgaa aaacctattc aaatccatca cttttgattg tggaaaggaa
      781 ttttcaaatt ggaaacagat cagtaatgtc aatgatattg ccatttattt cgctgatcca
      841 ggaacgccgt ctcaaagagg cctaaacgag aattctaacg gattgttacg tagagatggt
      901 ttattgaaat ctatggattt caattcagta gatgaatttt ttattcaatc tgccgcatct
      961 aaacgaaata atattcctag aaaatcactg gattatcgaa cacctttgga agtatttttg
     1021 agttacgtaa gtattgatga tctgtctaac ttaatttgac aattaagatt atattaaata
     1081 ttatacagat aataacggaa tattatcatc gaaacagcta acaaaattgt cataaaaaac
     1141 gagatggttg atattagaac ttgtgttttt gtttaggtct agagataaag agagacaatt
     1201 tccaaatata tgtaatgaat acaaaaagac gtttgtcgcg gattaccgtt acaaacgtct
     1261 tttattgatt ttccgagatc tcatcagtcg ccatttggaa tggttcactc cttatctaga
     1321 ttcgtttaat gctcggactg cttgttcgat tgtaatacca aacgcaacgt tattttcgtt
     1381 ttgtgcatca atcgccataa aacggttaga agttgtatca aaagctacgc ggtattgcat
     1441 atttgttttt gtaaacgtca taaaattcat ctcctttgta atgtaattta gttcttgaaa
     1501 gtttccttta aactttcgaa cttataccaa gtttagcatc gtacgttttt tgatgcaatt
     1561 aaaaagcatt tatcattttc cttatttatt ttttcttaaa tggtttagct attttctttt
     1621 aatccgataa gtagcccaat catcaaggtt acaaatacta ttgcttgaat ataaatcata
     1681 tgctcacctc tttataaata acttagcaat ataaagaaaa aaacgcacga acaacatagg
     1741 aatataaaca aacgtttttg tcacaacgtc taagatcgtg ttaaaaaata gttatctaaa
     1801 aagcagaaag atactcaaaa taaaaaataa aaaaatggat aaaaacgttt tcaaatacaa
     1861 ggtaatttgt tattataaaa taaagaaaaa acaaaataaa aataaagaaa agagggaatg
     1921 aaatggtaaa agcagaagta ggaagatctt atatatgcaa accgatcgga gtatctcatg
     1981 aactaatcgg ctgtattgaa cgtacatata tcaacacggc tgtcgtgtat gttgaaagtt
     2041 atgaccaacg agactatcaa cttatcaatg aaagcaagta tcgcatgctc gtaaaattct
     2101 gtgatattag cgcacctgct gaattggttt cttaaacagt atttttgaga attcgcaaga
     2161 actcccttat aatataaata aagacagaag ggagcgagaa gatatgccaa aaagaaaaag
     2221 ttcagggaaa atgggaatta ttcttgcagt gatctctgca attcctgcta ttttagctat
     2281 tgttcgtgcg atgaaggaat caagagaaag ttaagcacac attatgagcg tcaaacaaaa
     2341 aa
//
LOCUS       DADVXV010000179         2114 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.187, whole genome shotgun sequence.
ACCESSION   DADVXV010000179 DADVXV010000000
VERSION     DADVXV010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2114
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.187"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..172
                     /locus_tag="KB969_002906"
     CDS             <1..172
                     /locus_tag="KB969_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBB6870810.1"
                     /translation="NNKISFEENIVKEMPESANDMYEKELKYFFENVVTGKENWNDLY
                     HANEVLKIAEEK"
     gene            173..925
                     /locus_tag="KB969_002907"
     CDS             173..925
                     /locus_tag="KB969_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBB6870811.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            930..1877
                     /locus_tag="KB969_002908"
     CDS             930..1877
                     /locus_tag="KB969_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBB6870812.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          741 a          279 c          421 g          673 t
ORIGIN      
        1 aaataataaa ataagttttg aagaaaacat tgttaaagaa atgcctgaat ctgctaatga
       61 tatgtatgag aaggagttga aatatttctt tgaaaacgta gtaacaggca aagaaaactg
      121 gaatgattta tatcatgcaa acgaagtatt gaaaatagct gaggagaaat aaatggaaat
      181 tttatttact atttgtggta gagctgggtc taaggggttt aaaaataaaa atttgaaata
      241 tttggcagga aagcccctag tccatttcgc tttagcaatg atagatatct atcaacaaaa
      301 acatcctgaa cataattgca cgacttgttt gaatacggac agtaatgagt tagtagaatt
      361 gacgactaag ttaaatccgt ctgtgaaaat tgtagaacgt aaacctgaat tagctacaga
      421 tactgtaggg aaaattgaag tgatacgtga ttcattctta caactagaaa gagaagataa
      481 tatatttgat ttaattatag atttagattt gacttcacct ttacgtgaag tttctaatct
      541 tgaagaatta atagatgaac atctaaaaaa tttagataaa gacgtctact tttcagttgt
      601 ttctgcaaga cgtaatccct attttaatat ggtaaaaaga attgaaaatg aagttactat
      661 agttaataaa tcaagataca catctaggca acagacacct gaagtttttg aaatgaatgc
      721 ctcaatgtat tcttttaaac ctgaatttct aaaaaaaagt aattatattt ttgatgggca
      781 atgtgggata ataaaaatga gagattatct aattttagat attgatagtg aagaagattt
      841 taaatggtta gaatttttgt ttcctaaatt tttagaagat tcttcggagc ttcaagatat
      901 ctataattat ttatatcgga ggtaaaagga tgagctgtta tcttatcacc ggtggggctg
      961 gcttcattgg ttctacctta gccaatcatt taggagaaga acatgtggta atcgtcgtcg
     1021 atgacttatc aatgggaaaa gtagaaaatc ttgatatgac gaaaaatatc acttttattg
     1081 agggagatgt cgctgagaaa tccttgatgg aagagatcat gaaagctaat aaatttgatt
     1141 atatctttca tttagcagca gttgctagtg tggcagattc agttgcccga ccagtagaaa
     1201 cacatcgtgt gaattttgaa agtgtattaa tgattttaga attgatccgc aagtatcaac
     1261 ctgatttaaa acggatcgtg tttagttctt cagcggctgt ttatggggat gaaccgactt
     1321 taccaaaaaa agaagagtcc gtgattcgcc cattgacgcc ttatgcggtt gataaattcg
     1381 ctgcagaaca atatgtgcta gattattgtc atttatatga tgtacccggt agcgcagttc
     1441 gttttttcaa tgtctatggt ccaaatcaaa atccgaattc tccatacagt ggtgtgattt
     1501 ctattctcgt agatcgctat aagaaacaaa tcgtaggaga agcaacttca tttacattat
     1561 ttggtgatgg aagccagtct agagactttg tttatataga tgatgtaatc caagcattac
     1621 ttttagttgc gaatgaggaa gctgcactgg ggaaacaatt caatgttgga acgggtaaag
     1681 caaccacact tttggaattg attcatgcaa tcaatgaaat tctcggtgta gaattgacac
     1741 ttgaatacaa agaagagcgt tcgggtgata tccatgactc tctagcagat attactaaga
     1801 tccagtcaat tggctatcaa ccgaaatatg gtattttaag tggaatgact aattatttga
     1861 aaactgaaat caattaaaac atactaagat aagattagag ggtaaattca ggctctttgt
     1921 caataaggac tgatgagttt tgtaaaatca aatctgggat agaagggctc tttgtcaaat
     1981 gatgttggta aagagaaatc ttagaataat ttggacagaa cagaaagaag aaaacctctt
     2041 tctgttctgt ttatttggtt aaaaatgttt tgccatgacg aatcataatt cgtagtttga
     2101 aattgtaaaa gttg
//
LOCUS       DADVXV010000180         2058 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.188, whole genome shotgun sequence.
ACCESSION   DADVXV010000180 DADVXV010000000
VERSION     DADVXV010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.188"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(33..458)
                     /locus_tag="KB969_002909"
                     /pseudo
     CDS             complement(33..458)
                     /locus_tag="KB969_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
     gene            complement(567..1598)
                     /locus_tag="KB969_002910"
     CDS             complement(567..1598)
                     /locus_tag="KB969_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6870813.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          639 a          337 c          354 g          728 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg ttaggaatct gttttgattt tgttccattt
       61 gaaatttctc tcactcgctt ttttgtctca tcatcaaata aaatgaaagg gtcttctaaa
      121 cgatcgataa atacttccat tgttgttgtt ggtagatgat aagaagtcat gacaggcact
      181 gcaccaaggt aagacacaga aacagctaga aggtatgtgt caaaagcgga actcttataa
      241 ataataactt tgtctccgga tttcactcca agatgagcca attgataagc ccgtttcaac
      301 acactttcgc agcatttttt gtaagttgtt tcaagtccta attctgggaa agctgaaagt
      361 ggctcatcaa agataatcgg ggtctcggaa aagttagctg cagcttcttg aaaattcgta
      421 aataagttca aaggggaata cgttatggtc tccatcattc acactccatt atcttttgtt
      481 aagtaatata caaattcaag ataatcgtaa cataatcctt tatataataa catagtttat
      541 tgtgaaaaaa agatcataca tttgttttat atggaagaaa cccgaacgaa tgccgctaat
      601 tcgtgataag aaaaatcaac catcttttcc cagatatctt gaaaagaatg ggatgagagg
      661 tatcgattac cacataaata atttaccgcg tcagcatcat ctaaatatag ttctgcataa
      721 taacgatatg tttttctgca tagttctggc gatacgtttt tatatactgt aattttgctc
      781 aaaatttggc gaatagtccg aggagaaatt tgctgatcat gtgaggaacg aaaaacaaaa
      841 gaattttcgt ccgtattttg tgctgttaac ttaaaatagt tctccagaaa tggcatcgct
      901 tcttttggta ttggtacttt attcagtctg ttttcttttc tattcagatt aagaatctgc
      961 ttggtcaaag atacatcttt acgtttaagt tctactactt catggatctt taatccgcaa
     1021 tacagaagaa tggcagtaat tgcaaggttc ctcggtctat tcttttcttc aaagctagct
     1081 tctctgcttg tttgaaagcc ttcaatcggg ataaacaaat gctcaaaatc tttgaaaagt
     1141 tctgcatcga tatatcgcgg agctgctttg gttgtttccg gtaaacttgt acccaaaaga
     1201 gaaatctctt cttcaatcag tcctttttga tacaaaaatc gtaaaaaatg atttaatgaa
     1261 tattgcttcc ttgaaatccc gtaatagcta ttttcaaaca attgctccgt ttcttggttc
     1321 gctgtagttt ggaacgaacg agtatgtcga tagattttag ctaagaaatt ctgataatct
     1381 tgtttttcta aatggataat cagctgatca tccacttctt cagaaaatac ttttctcaaa
     1441 taatcagtaa acagatgaaa atcttttgcg tattcatagc gactgcctaa tgaaagggaa
     1501 gaacgatttt cttctaaaaa ctgttgaaag acggaaggga gcaagtgtgt acgttgcttt
     1561 aacttttctt gcagttgttt tctagttttg ctgtccatta caaattccct ccaatagtgt
     1621 tcattttcta tattttaccg catttcatca aatgaagata gacagtttgt cttgatctta
     1681 ggaagcaaat ttttaactaa gtactagcta aaagatatga agtaagaaga tacattttta
     1741 gttattttat tagtgcagtc attcttttga tcttttaatt gatttatcct ctttttagct
     1801 atgtggttac ttcatgagca atgaaatgga tttggttcgt tctaatggca ggaggctctt
     1861 tcttttattt ccgaaaaatt agaaaacatt ttttcagaat cgattggctc tccatttatt
     1921 caataatggt ttgtctaacg atattgttgg gataattctt aaagaagtat tagaaatagt
     1981 tggtacttca ttactttaca tgaagattta ttctatggta ggagcaatta tattgagaat
     2041 taatcctttt ttatataa
//
LOCUS       DADVXV010000181         2056 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.189, whole genome shotgun sequence.
ACCESSION   DADVXV010000181 DADVXV010000000
VERSION     DADVXV010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.189"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..493)
                     /locus_tag="KB969_002911"
     CDS             complement(<1..493)
                     /locus_tag="KB969_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBB6870814.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAK"
     gene            complement(490..1143)
                     /locus_tag="KB969_002912"
     CDS             complement(490..1143)
                     /locus_tag="KB969_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBB6870815.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1431..>2056
                     /locus_tag="KB969_002913"
     CDS             1431..>2056
                     /locus_tag="KB969_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870816.1"
                     /translation="MDNHTRKLLVLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPR"
BASE COUNT          663 a          356 c          263 g          774 t
ORIGIN      
        1 attttgcata aattaaagaa ataatagcag aaaataaaat tgatattaat aaagaatatg
       61 gtaaaaattt aaggcttaaa tctttcgcat ctttttgcat atcagctgta gaaacaaatt
      121 gtagatttgt ttttttacca tcattaagct ttatttctct ttcttcaatt atcaaagaat
      181 tactatcact ttctaaatta acatttatat tatctttgat ttgtatttca ttcttattat
      241 ttttttcttt tatgaatact tttatttcac tactcttgga ataaaactcc aaagtttgtt
      301 ctatatattt tatttctttt ccattcatat tactagaaat ttcatttgcc atattatgaa
      361 tcttttcttt tctcgtctcc aaatatgttt taggaaagat aaaaaaaatt aatgaatgaa
      421 ctaatataat tattattcca agaacagaaa atatttgtat gaacattttt ggaaatatct
      481 ttaatttttt cattttctct ccaatttata tcctacattt cttatagtag ttatacagtc
      541 taattgtaat ttttttctaa gttcttttat atatacatct attactcgat cataaggagt
      601 ttcttcgcta tctttccata cataatcaat aatttgcatt cttgttaaca cttgtccatt
      661 attatccaat aaacatttta atacttctag ttcttttgca tttacatcta tttcttcacc
      721 atttatttta gctgtatagc tattaaaatt aaccgataga tccttatatt caaacttctc
      781 taaatgtcca taattcttct taattaaaga atctattcta gcttttaaga ccggcaatga
      841 aaatggcttt tctacatatc cgtctactaa attagtaaat gcatcaattt tatattcttc
      901 atcactaaat gcagtcaaga ttagaattgg taaattgctt ttctttctaa tttctttcaa
      961 cacttctaaa ccatttataa aaggtatctg aatgtctaag ataaccaaat ttatatcgct
     1021 attaaatttt gacaaggctt ctcttccatc tttagcttga ataacagtat atccaaattc
     1081 tgaaagatat tcacttattc cctctcttat catattatca tcttcaacag ttaatatttt
     1141 catatatacc tccacttaag cctatacact agatattata cagcatatta tggctctata
     1201 atatctagtg ttggtgacac cttctgttgc caatactttt tcttttttct aataaatgca
     1261 aacagacacc ttgaaatcct ttagaataaa gggttctata atattttgtg ttgttggaaa
     1321 atcgaaggcg attttctact aacacttttt cttcgtttca actcaaaaag agactcactt
     1381 ttggtaaaat ttagtcgacc aaaacatcac cctaccaaag gagtcgctct atggataatc
     1441 atactagaaa attactcgta ttaacagata aacatttatt ttttgatgaa gaatggctga
     1501 ttgaaaaaga atataaaggc gttcaagcgc agtttattaa agggagattg gatgactcac
     1561 cttcccattg tgaacactgt ggatcgattc gtattatccg caacggttcc tatacgacac
     1621 gtactcagat attgaaagtc aaagaaaagt tgactatttt agaattaaaa cgtacccgtt
     1681 ttctatgcta tgattgtggg cagacctttt ctgcgaaaac ggacttagtt gatgaacatc
     1741 atcaactaac aaaggaactg aagcaggcga ttctcataga actgtacgaa aatcaatcac
     1801 gtaaactaat cgctaagaag tacttcgtct cggatgggac ggtgacacgg atcttgcgtg
     1861 aagcaacgaa gcattaccag ccacgtatga acttccttcc gacggtgttg tgtatggatg
     1921 agttcaaatc aatgaagtct gtttctggtt ccatgagttt tatttgtgtt gatgggacaa
     1981 cccatcagct atttacgatc cttgaagatc gcagacttta caaactaact caatacttcc
     2041 tgcgctttcc tagaaa
//
LOCUS       DADVXV010000182         1963 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.190, whole genome shotgun sequence.
ACCESSION   DADVXV010000182 DADVXV010000000
VERSION     DADVXV010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.190"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..>1963
                     /locus_tag="KB969_002914"
     CDS             <1..>1963
                     /locus_tag="KB969_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6870817.1"
                     /translation="QIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRV
                     VTLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSL
                     LQYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQ
                     SEVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPG
                     CDKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDS
                     LSEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGY
                     VVLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNAN
                     FIQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGT
                     IGTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFG
                     DLDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFT
                     KQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNL
                     FNAAGIKEPITSLDAQVRLLIWTFTNGQWM"
BASE COUNT          711 a          255 c          401 g          596 t
ORIGIN      
        1 caaataaaag caaagccaaa cgatcaagaa gagtatcata tcttttttat tgatgataaa
       61 gatatagata cttttttaaa tacagtaact atttatgctc agagtcgtac aaatcgactt
      121 ggaagacggg tagtcactct tgtggaagtg gactctaaaa ctggtcaaga agcgatatca
      181 attattgaaa ctaaaatgga taaaaaatct gacatacgac tttattctga tattacggct
      241 gtttctagca caatctttga agcgagaaat gttttaaatt gtattgctgg tgaacaagga
      301 tcattgcttc aatattgggg cggagaaatt aaacgtgaac catttaagct ttctttgtta
      361 aagcgaagag gtcgcaataa tgttggaacg attcggtatg gaaaagatat gtctggtttg
      421 aaggtcaaat tagattggac aggtataaaa acaagaatta ttccatatgc tgatcctcaa
      481 agtgaagtag gtacgactaa tcgaatttat ggttcgccag tagatagtgc ctatattaat
      541 aactatcctg atgtctatac agaacatgtt cagtttacag aagaacaagg agtaaaagac
      601 attaagagct taaataaaat agctaaaaat tactttaaaa cgatcaatcc tggctgtgat
      661 aagcctaaag tttctattac ggttgaattt gataagttga ctgatagtga agaagcgaaa
      721 gaatttgcga agattagaaa ttatggtctg tttgatacat ttaaaatata tcataaaaaa
      781 tataatattt atcttgaatc aaaggttagt ggactacaat acgattcttt atctgaaaaa
      841 actttgaaat tagaagcagg agacattcaa gttgcttttt atcagcaaca agctgtaact
      901 attcaggata aattaaaaga ttatgcaacg aataattata tgagtgattt taatgattat
      961 gtttcttcaa tgattacagg tcaaggcagt gcaggaggat atgtagtttt atggccaaaa
     1021 gaaaaacctt ccaacatctt tattatggat aatccagatt tagaaaaggc aagagaagta
     1081 ctaagaatga ataaaaatgg gattgctttt tctaagaaag gatggcgggg gccttttaat
     1141 tcagcttgga cattagatag tatatttaat gccaatttta tacaaactgg attaatcaaa
     1201 gcagatatct ttcaaaattc ttttaacaag actggagatg tattgaaatt agttaatgga
     1261 ctactccaaa tttggaacaa caaaaagaaa ataatggagt taactaaaaa aggaatggaa
     1321 ttttggaatt ctaagggttc aattggaacg attggaacaa ctgattctgt tggtaatcct
     1381 tttcctgggg cttctactcc aacccctatt gaagataatt ctttagttat tcgtacaaat
     1441 ggagacggca aatatatttt gatttctcct aaagtaggaa aaggattagt tttattagga
     1501 aatggtaaag caatttattt tggagactta gatgtacaag gaaaacttac agttaaagga
     1561 aaagaaataa ttcctggaca aggtggtggt ccatcgggag gtggagaatc tactggtggg
     1621 tatcctagtg aattaaaaac agatgcagaa aagagagctt ggagaattta cgatattttg
     1681 tgtaataacg gatttacgaa acaatctgca tgtggaatat tggggaacat tcaacaagaa
     1741 acaggaggaa cttttgatcc tgatactgtt caaataggtg gaccagcata cggattagtt
     1801 cagtgggatg gttcttcata tcctcttgtt ggtccagcaa catgggatgg aaaagtttat
     1861 gttcaaaact tatttaatgc tgcaggtatt aaagaaccaa taacgagctt agatgcacaa
     1921 gttcgattgc ttatttggac atttacaaat ggacaatgga tgg
//
LOCUS       DADVXV010000183         1956 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.191, whole genome shotgun sequence.
ACCESSION   DADVXV010000183 DADVXV010000000
VERSION     DADVXV010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.191"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            125..1246
                     /locus_tag="KB969_002915"
     CDS             125..1246
                     /locus_tag="KB969_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBB6870818.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            1666..1902
                     /locus_tag="KB969_002916"
     CDS             1666..1902
                     /locus_tag="KB969_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBB6870819.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFLMILFVKLSETKLSIYVTQKNF"
     gene            complement(1855..>1956)
                     /locus_tag="KB969_002917"
     CDS             complement(1855..>1956)
                     /locus_tag="KB969_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBB6870820.1"
                     /translation="VASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT          644 a          374 c          352 g          586 t
ORIGIN      
        1 aattactagt gttgcaaaga ctttttaacc catcaaaagc ctaatacaaa gctatccaaa
       61 cgcaaaaaag tcctttatac tattctcgga tgacttatcc aagaccaata aaaaggactc
      121 acgcatggat aagtataacg taaaaacctc atttcaaaaa tggttttctg caataaattt
      181 ttctggttta tcagaaaact ctcaaagctt aattagcgac tttgatttct acagtaaaaa
      241 actagacttc caaacgacgc ttaaagtgtt acttcatgcg gtttatgaag aattgccaag
      301 ctatcgcgag attgatcgcg cctttttaga tcagcgcctc tgcaaggaac ttggcattga
      361 ttccctgtgt tacagctcgt tatctcgtag agcgccagaa atcaagcaag aagtattgat
      421 ggaaattttt acgcaattag tcgccagaat ttctgctcag cagccaagct caaaaacaac
      481 cagtctacaa ttgattgatt caacgactat tccgttgaac aaagcatggt ttccatgggc
      541 caagtttcgg aaaacaaagt ctggcatcaa gctacatttg aatctctgtt atcttgataa
      601 aaccaatcag tatcctgaaa gttttacgat gacaaatgcg agtgagcatg accgtaatca
      661 ccttgaagtt cttgttgata aaacgcaagc aacgtatgtg gtggatcgcg gctactttga
      721 ttacaagttg ttagacaaac taaatcgtga cggctatttc ttcgttacac ggacaaaatc
      781 taatacaaaa attaccatct tggatcaaat tgaagtagca gatacaacaa cccgtgatgg
      841 gacgataatc agtgaccaac aagtgattct tgtcggcggt gtcaaccatg tgacagagcg
      901 ttttaggttg gtaacggttc ttaccaaggg acaaaaaatc ctgcgaatgg tgaccaatct
      961 ctttgatgta tcgccaaacg aagtggccga catgtatcaa gcccgttggc agattgaatt
     1021 gttgttcaaa cacttaaaac aaaatctgac cattaaacga ctatattcac atagtgaaca
     1081 aggggcgata aatcaagtca tcctcacctt aatcgcaacg cttctcactt atgtgataaa
     1141 aattgagttg aatacgacag cgacgctgtt tcaattgaaa cgtaccttcc attacttaat
     1201 gtttgagccc gcagaagagt ggttcaaacg ttacagacct ggatgaggat gtagttaata
     1261 gctgttgtca cgtttgattt ttgaatacat actaaaattt tctggaaaat agtcatccgc
     1321 tgcgtcagca cttgactttt ttgaaatttt tagcaagaaa taaatgtcag actattctga
     1381 cgatatgttc gcaacattag tgatactaaa tagatttttc gctatctttt tataacttca
     1441 catatgtccg aaaagcctta ttttacaggc tttccggaca tattcactat cttgcttacc
     1501 tcaatcctaa taaaacattc ttttcaacat cagtgagcat agcaggtcat agatatctta
     1561 atccttttgc aagtatcttt tcaaaagctg ttgttgtata ctgaaatccg tattgttaca
     1621 ggaatactga agttgtgaca aaaacatagc catcaaggaa aaggtattgc gactaaaatt
     1681 gcagatgaat tggaaaacca tgttttagaa actggtatgc aaaaaatcac tacccacgct
     1741 tccattaccg caaagccatt ttttgaaaaa cgaggatata aagttattaa tgaacagacc
     1801 gtggaactta gagggcaatt atttactaac tttttaatga tattatttgt caaattaagc
     1861 gagacaaaac tttccattta cgtaactcaa aaaaacttct aatggtgttt ggtaatttag
     1921 tgattttcta gggatatggt ttcttttgga cgcaac
//
LOCUS       DADVXV010000184         1901 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.192, whole genome shotgun sequence.
ACCESSION   DADVXV010000184 DADVXV010000000
VERSION     DADVXV010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.192"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..794
                     /locus_tag="KB969_002918"
     CDS             <1..794
                     /locus_tag="KB969_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6870821.1"
                     /translation="LACRLRKVSYALNITGLGTAFQKKGVLKSLIVFLYRLAAKKSKV
                     IFFENFENMKTFQTLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVHFLFIGRIMKE
                     KGVDELFEAMKNLYSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYHGYQSDIRPFV
                     ERAHCFVLPSWHEGMANTNLESAASGRPIITSDIPGCKEAVIESKSGYLCERKNSCSL
                     YNSMNKFLKLSYEQRINMGKMGRNYMIKKFNKKKVVDETIKSLFS"
     gene            801..1196
                     /locus_tag="KB969_002919"
     CDS             801..1196
                     /locus_tag="KB969_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6870822.1"
                     /translation="MFCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMME
                     AMASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNEN
                     LSRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            1193..>1901
                     /locus_tag="KB969_002920"
     CDS             1193..>1901
                     /locus_tag="KB969_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBB6870823.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKA"
BASE COUNT          742 a          212 c          379 g          568 t
ORIGIN      
        1 gattggcatg tcggttaaga aaggtttctt atgcattaaa tataaccgga ttaggaacgg
       61 catttcaaaa aaagggggtt ttgaaaagtc ttattgtatt tttgtataga ttagcagcta
      121 aaaaatctaa ggtcatattt ttcgaaaatt ttgaaaatat gaaaacattt cagactttac
      181 aaattgctaa acaaagtaaa tacaagctat taaacggtgc aggagtagat gtagaacact
      241 ttagttattt agaatatcct aaagatgagc aagttcattt tttatttatt ggaagaatta
      301 tgaaagagaa aggtgtagat gaactttttg aagcaatgaa aaacttatat agtgaagaga
      361 aaaattgtgt acttgatgtc cttgggtatt ttgaagaaga ttacggcata aaaattgaaa
      421 aatacgaaaa agagggatgg ttaaaatatc atggatatca atctgatatt cgtccctttg
      481 tagaaagagc acattgcttt gttttgccta gttggcacga aggaatggca aatactaacc
      541 ttgaatcagc agcatcaggg agaccaatta ttacaagtga tatcccaggg tgtaaagaag
      601 cagttattga atcgaagtct ggttatttat gtgaaagaaa aaatagttgt agtctctata
      661 attcgatgaa taaatttcta aaattatcat atgagcagcg cattaacatg ggaaaaatgg
      721 ggagaaatta tatgattaaa aaatttaata agaagaaagt tgtcgatgaa acaattaaat
      781 cattatttag ttaaaaagat atgttttgca aagtatgtga tagaaaagag ggattctgtg
      841 gcttcagaat agatatcaaa gaattggcaa aagtttctga tattttttta tttactacat
      901 tacaagaagg aatgccaaga tctatgatgg aagctatggc aagtggattg ccatgtatag
      961 caagtaaaat ccgaggtaat gtagaccttt tagtggaagg aaaaggtgga tatcttgttc
     1021 cagctaaaga tgcagaatta gtagcagagt gtttgagaga actaatcaat aataaatctc
     1081 ttagaaagta tatgggaaat gagaaccttt ccagaattaa agaattcgag gttagtatcg
     1141 taaaaaaaag aatcaaagaa atatatgaag aagttatagg tgagagtgta aaatgaaaaa
     1201 tccaatgttt tcaataatag tacctatcta ttgcgttgaa aaatatttga aagattgctt
     1261 agattcaata agaaatcaga catttaaaaa ttttgaagca atactagttg atgacggtag
     1321 tcctgacgaa tgcccagaaa tatgtgacta ttattcccaa atagatggac gtttaaaagt
     1381 aattcataag aaaaacggtg gaataataga tgcacggaaa acaggagtca ctagtgctat
     1441 gggagagtat atagtttttc tagatggtga tgattggctt gcaaatactt atttagaaaa
     1501 atatgcggaa gtaattacta agtacaatcc agatataata tgtagtgggt attttgcatc
     1561 acgttccaac aaaattagaa aaagagaatt gtcttgctcg tttggatatt atgacaaaga
     1621 taaaattata aatttgattt atcctaaatt aattgaggat gaacatggag agtattttag
     1681 accacaatta tgggcaaaag cttttagaac tactctgtac aaggaacaac aacaagtatc
     1741 tgggcaagtt agtgttggtg aagatcatgc atgtacaaaa ccatgtattt accatgcaaa
     1801 ttcgatatat atgatggaaa aatgtttata ttattacaga ataaacgaaa attctataac
     1861 aaaaaaacca caaccatatt attgggaagg accaaaggct a
//
LOCUS       DADVXV010000185         1859 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.193, whole genome shotgun sequence.
ACCESSION   DADVXV010000185 DADVXV010000000
VERSION     DADVXV010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.193"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            416..1804
                     /gene="ltrA"
                     /locus_tag="KB969_002921"
     CDS             416..1804
                     /gene="ltrA"
                     /locus_tag="KB969_002921"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBB6870824.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT          654 a          343 c          444 g          418 t
ORIGIN      
        1 aacttggtgg tgaaagtcca ctacaggctt ggcagtagga actgttagcg aaagacaagg
       61 cggcaatcgt gaggttgtgg ctgaaggaag tcggacgcaa actcctgaac tgacgaacag
      121 aaactagata caaggctgaa ttaggtcgga taagtcttca tcacaagaca aagtccaata
      181 ctgcccgaaa cctatacagt aaatctagca gttacatggg aggaaagttt tcactcttac
      241 cgggggagat ctcatgaggg tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc
      301 atggcgacat gatggtgaat catgagaagt cagccgaggt catagtagta acgacactga
      361 ccgttacgaa ggactgaaca ataagaatct tgaataattt aggaggtgtg agaagatgcg
      421 acgaccgcag aaaacaagaa aacttggcta tcatcaaaga gctagtgtgg aacacgaagg
      481 gtatgatgaa gtgcgcagca cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa
      541 tctgtttggg agaattctag atcggaataa tctcaatcaa gcgtatcttc aagtagtcag
      601 aaataaaggg gcggctggtg cagatgggat gaccgtcgat caactgcttc cttacttgaa
      661 agagcaccgc gaggaattac tatccaattt acgccaaggg aactataaac ctcagcctgt
      721 tttgcgagta gaaataccga aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt
      781 tattgatcgt atgcttcaac aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga
      841 attctcagat aatagttatg ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa
      901 agcaaaatct tattatgaac aaggttaccg atatgtggtg gacattgata tgaaagccta
      961 ctttgacacc gtaaatcacg ataagctgat gtatttcatt gagcggaaag taaaggacaa
     1021 acaagtccta aaactgatcc gtcaatactt aatgagtggt gtaatggaaa atggactcat
     1081 cacaacaact gaagaaggaa cgccccaagg aggcaatctc tctcccctgt taagtaacat
     1141 ctacctgaac gaatttgatc aagtgctaga aaatctagga cataaatttg ttcgatacgc
     1201 cgatgactgc aatatctatg ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc
     1261 cattcaattt ctcgaagaac aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg
     1321 aagtccattg aaacgaaagt ttcttggatt ctgcattctg ccaacaaaga aaggtattaa
     1381 aattcgccct cacgcaaaag caaaacagcg tgtgaaaagc aagctcaaac aactcactaa
     1441 aagaaaccgt ggaagaagta tccaacttat tttaaaagaa atcaagcaac taatgactgg
     1501 ttggatcaac tactatggaa ttggtgagat gaaagaattc atgagggagt taaacggttg
     1561 gttgaagcga agaatcagac aatatatttg gaaacaatgg aagaatccaa gaaccaaaag
     1621 aaaaaatctg attcgtttag ggatcgataa agcgaaagcg tatgaatggt caaatacaag
     1681 aaaaggtatt tggtcagtct ccaaaagtca tattcttcat cgatcattaa cagacaaaga
     1741 actggcccgc caaggatatg aggacatctc cttgaagtac cagttcgtac actcaactta
     1801 ttgaaccgcc gtatacgggt ccgtacgtac ggtggtgtga gaggggcgga aggtcagtt
//
LOCUS       DADVXV010000186         1784 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.194, whole genome shotgun sequence.
ACCESSION   DADVXV010000186 DADVXV010000000
VERSION     DADVXV010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.194"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            180..416
                     /locus_tag="KB969_002922"
                     /pseudo
     CDS             180..416
                     /locus_tag="KB969_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            575..>1784
                     /locus_tag="KB969_002923"
     CDS             575..>1784
                     /locus_tag="KB969_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBB6870825.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVL"
BASE COUNT          566 a          339 c          332 g          547 t
ORIGIN      
        1 ttcgcaacga tagcaaccgg agtttcttga tgaaaatatg cttctatcat tacaagctcg
       61 tttggtgtaa gatgggtata agtcatttat gttcactctc cttgtatgct ttagcgggta
      121 ttacaattgg agtgtaacat aaatggcttt tttatttgtc tcgcttaatt atacaaacgg
      181 cgttattaaa aaatcttcct gaaacacttg atgcacaact tcgcacgaaa cttcaaaacc
      241 ttttaacgta tgaagaaggt atttacaatg ctatgattta cccgtattct aatggcaaaa
      301 tagaggccaa gattccccat atcaagacac tgaaacgatt atcttatgga tttaaatcat
      361 ttgagaacat gaaaatcagg atttttttga tcaatcaatt gattcaagtg aaataacaaa
      421 aaaatctgag acagaaggtc agtccttcta tcggctctat actttttgat gttggtgaac
      481 ttcaccaaca tcttttttgt ataaaaaaat atagaaaaga caccctgaaa tcctttagaa
      541 ttaatttggc taccaattca taggaggatt caagatgtct catactcagc ttatcaaaga
      601 taccctaaat attctagacc taaatatcta tttcgaggaa aattgtttaa ctaaagaaaa
      661 atacaaaggg caaatttgct tgatttacaa aggaactctt ctgtacaagc cagaagagtg
      721 ttcccattgt ctttgtgtcg tcccctctag gatcattcgt tgggggacga caaccgttcg
      781 gttgttactg aatgatgtgt ctgagtatcg cacttatctg gagctgaaga aacaacgatt
      841 taaatgtaag tcttgccaaa gaacattcgt agcggatacc tctgttgctg aaaaacactg
      901 tttcattagt caaaaagttc gttggtctgt cattgctcgc ttaaaagaga atacttccat
      961 gacggaaatc gctcgtcaga aaaatatttc cacttcttcg gtctatcgtg tcatgaagcg
     1021 attctaccgc ccattgaatc ctttcaaaca gactttgcca aaggtcttat gctttgatga
     1081 attcaaatcg gttcgaagtg ttgccagtgc aatgagtttt atcatgatgg acggacaaag
     1141 ccatgcatta ttggatattg tcgaaaatcg acgcttgcct tatttagaac gctatttttc
     1201 tcggttttca ttagcgactc gtgaagccgt tcaattgatt gttattgata tgtatgcgcc
     1261 ttatgtttcg ttggtgaaaa agcttttccc gaatgctcag ttgatcatcg atcgtttcca
     1321 catcgtccaa catattggca gaactttctt gaatcatcga gtgaaagaaa ccacggtacg
     1381 acttaaagga aattcccact ctcaacgagg gttagggaaa aaattgaagc gctattggaa
     1441 actcctacaa aaagaagaag caaagttaaa ctatgaaaaa cgggtttggc gtgccagttt
     1501 taaagattat ttgactgaaa gtgagattgc cgatcgactg ttagctgctt gtcccaactt
     1561 acgccaaggc tatcagttat accaagacat tctttatgcg gtaaagaaaa gagatcagtc
     1621 actatttgag gattgtttaa ctagagacat tagcggtctg ccagaaacct atacaaccac
     1681 tttacgaacg tttaaaaagt ttctgccaca gatccaaaat gcgcttcact acagctattc
     1741 aaacggacca ttggaatgct taaacaacca catcaaagta ttaa
//
LOCUS       DADVXV010000187         1783 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.195, whole genome shotgun sequence.
ACCESSION   DADVXV010000187 DADVXV010000000
VERSION     DADVXV010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.195"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..1547
                     /locus_tag="KB969_002924"
     CDS             <1..1547
                     /locus_tag="KB969_002924"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBB6870826.1"
                     /translation="RSKMDASEYKNYLLGLIFYKYLSDRLLEQVVLLADESLEEYDTV
                     SKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLADQAKQATFQLNDLNKA
                     FVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKKLNDVEVLGHDGDVIGD
                     AYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERRFFSVFDPTMGSGSLML
                     NVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMNLRNGDTLNKDWPTDEP
                     YTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADFAFLLHGFYHLKETGTM
                     AIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGTSIPTTVIVLKKNRQTR
                     DVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYAHLANFDEIKENDYNLN
                     IPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAISSLQTTPENEAWLQGAL
                     EVFKHE"
     gene            1540..>1783
                     /locus_tag="KB969_002925"
     CDS             1540..>1783
                     /locus_tag="KB969_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBB6870827.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELI"
BASE COUNT          620 a          294 c          376 g          493 t
ORIGIN      
        1 tccgtagcaa aatggatgcg tcagaatata aaaattattt attgggactg attttctata
       61 aatatttatc cgaccgtttg ttggaacaag tggttctttt agcagatgaa tccttagagg
      121 aatatgatac ggtaagcaaa caaacgatgt tgtatcgcga attactttca gatgaagaat
      181 caaaagaaga tctgattgca acaatcgttg atattttggg gtatgcgatt tcgccagagt
      241 atcttttcaa cgtcttagcg gatcaagcaa aacaagcaac gttccaattg aatgatctaa
      301 acaaagcctt tgtgcaattg gcatctacct acaatcaatt taatgggtta tttgatgatg
      361 tggatctcca atcaaaaaaa ctaggaacag atgagcaaca acgaaatgtg acgattaccg
      421 aagtcattaa gaaattgaat gacgtggaag ttttaggtca cgatggggac gtgatcgggg
      481 atgcttatga atttctgatc agtcaatttg cttcagaagc agggaagaaa gccggagaat
      541 tttacacgcc tcatatggtt tctgatatga tggcacaaat cgtgacgttg gatcaaaaag
      601 aacgacgatt ctttagtgtt tttgatccaa ccatgggttc aggttcattg atgttaaatg
      661 tgcgtaacta cttaactcac ccagataacg ttaaatatca tgggcaagaa ttaaatacaa
      721 cgacatacaa tctagcaaaa atgaacttga ttttacatgg ggtagatgcc gaagaaatga
      781 atctccgcaa tggggatacg ttgaataagg attggccaac agatgaacct tacacatttg
      841 atgcagtagt aatgaaccca ccttattcgg ctaattggtc agcagatacg accttcttag
      901 acgattctcg gtttaatcgt tatggaaaat tagcgccaaa atccaaagca gattttgcgt
      961 ttcttcttca tggtttctat catttgaagg aaacagggac tatggccatc gtcttgccac
     1021 acggagtttt attccgtggc gctgcagaag gggtcattcg tcaaaaatta ctagaagacg
     1081 gcagtattta tgctgtgatc ggtatgcctg cgaacttgtt cttcgggaca tcgattccaa
     1141 cgacggtgat tgtattgaaa aagaaccgcc aaactcgaga cgtattattc attgacgcta
     1201 gtcgagaatt tgtcaaagga aaaaatcaga ataaattatc ggaagaaaac attcaaaaaa
     1261 tcctcgaaac ctatgctgaa agaaaagatg tcgagaaata cgctcatttg gcaaactttg
     1321 atgaaatcaa agaaaatgac tataacttaa atattccacg ctatgtagat acgtttgaag
     1381 aagaagaacc aattgatatg gttcatgtcg gaaatgacat caagaagata cgacaagaac
     1441 agcaagtgct agaaaaagaa cttttagaag ctatctcttc cctgcaaaca acacctgaaa
     1501 atgaagcgtg gttacaaggt gcgctggagg tgttcaaaca tgagtaatga tatacaacca
     1561 gaaattcgtt tcccaggatt tacggaagct tgggaacagc gtaagtttga atgcttactt
     1621 gataaaaaag atggagtaag gaggggacca tttgggagtg ccttaaagaa agaattcttt
     1681 gtatctaata gcaattttgt tgtctatgaa caacaaaatg ctatttatga taattacgaa
     1741 acaagatata aaattactga aaaaaaatat aatgaattaa tca
//
LOCUS       DADVXV010000188         1764 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.196, whole genome shotgun sequence.
ACCESSION   DADVXV010000188 DADVXV010000000
VERSION     DADVXV010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1764
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.196"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            154..1233
                     /locus_tag="KB969_002926"
     CDS             154..1233
                     /locus_tag="KB969_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBB6870828.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            1474..>1764
                     /locus_tag="KB969_002927"
     CDS             1474..>1764
                     /locus_tag="KB969_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HBB6870829.1"
                     /translation="MWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWYSCISMFVF
                     HIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSKLLE"
BASE COUNT          661 a          202 c          342 g          559 t
ORIGIN      
        1 caaatatagt tagaatgaaa gcatatgaac ttgaacctaa tatgagaaag aagttagccc
       61 ttgtgaccat tagtataatg tttaatttta aaatgtataa aacagcgtat aatatgctct
      121 ggagaatata taatcgataa agaggtagga aatatgagga aattgacctt tgtgatagga
      181 attatgggaa aaggaggggc agaacgagta attgcgaatt tggcaaataa ttttattcaa
      241 gataactggg aaattgatat tataactata tatgggaatc ggcaagacta tgaactgaat
      301 agaaaaatac aggtacatcc aataatatgt aaaagttcgt ttcgtgcatt tagacctttg
      361 gaacgcttta aggaacttag gaaaaaaata agggaaatac agcctgatct ggttatttcg
      421 ttccttgctg atgtaaatat ccatgtcatt atttcattgt taggagtaaa acaaaaatta
      481 attgtttctg aacgaaatga tccacaacgg aatccagaag aaccatggat taggaaaatt
      541 agagattttc tttataaaaa tgtagatgga attgtttttc aaacaccaga cgcaaaaaaa
      601 tattttagta agatcaatga taaaaaagta aaaacaatta taattcccaa cccaataaag
      661 gaaaatttac cttattataa taaaactaca agtagtaaaa aatttattac tgcatgtaga
      721 ttggataaac aaaaaaattt gcccttaatg attgatgcaa taggaaaact tattcatgaa
      781 ggatatgagt gtgaactgga tatttatgga gaagggggat taaaaaccga gcttgaaagt
      841 tatatcaacc ataatggatt aacagaattt gttcatctaa aagaatttac aaataaaata
      901 catgaaaaga tgcaaaatgc ggcaggattt gtaatttctt ctgattatga aggtatatct
      961 aattctatgt tagaagcact ggctattgga gtgccagtta tcgctacaga ttgtccagta
     1021 ggtggcgcaa gaatgtattt aggtgataga aatgaaatag gtcatcttgt tgaatgtaat
     1081 aatctagata agttaacaga tgcaatgcgt agggtacttt tggatagaga aagtgtggta
     1141 agaaaagcgc aaaaaggaat taaactaaga aaagaactga catctaaaaa tatttcaaat
     1201 atatggtacg aatatttaaa ccagttcttt taaccaaaag gaggatattg tgtgaaagaa
     1261 aaaataaata tattgatgtt ttcgttaacg ttagtcgcgt ttacaatatt ttgcgctttt
     1321 tcattaaatc agaactattg gctaaattgg cttggaatat tgatttactt atatgcaatc
     1381 tgtacatggc attggagaaa aggagattca atattttcat tatacacgat ttttttcact
     1441 ctttttttat tatttagtta tgggcaatgc attatgtggg cattcggtat tggaacagat
     1501 cgtggaatcg gtacaacagt agtagcttat ggtacgggga ttattcctag tgaatcagat
     1561 atgataatgg taaaatggta ttcttgtatt tctatgtttg tatttcacat aggagcactc
     1621 ttatttacga gaaaaaccac actaagaaaa gttagttggt atgaatctgg agatgctgat
     1681 gccgatagaa agtttttatt taaaataggg tgtatcattt ctataatagt agtaccgata
     1741 gtttttgttt ctaaattact agag
//
LOCUS       DADVXV010000189         1741 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.197, whole genome shotgun sequence.
ACCESSION   DADVXV010000189 DADVXV010000000
VERSION     DADVXV010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.197"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            49..1572
                     /locus_tag="KB969_002928"
     CDS             49..1572
                     /locus_tag="KB969_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBB6870830.1"
                     /translation="MDPTVFEAEEHIQKVIHKMFRPDNAYTKFDFRNGRPTKSAILTT
                     SSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTMEDPDFPRIAITYSLEENSRD
                     SSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNRLARKRAEFKQFGKQIDLVIV
                     VDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTYPEKTKGLIVTFRKPATMEKN
                     VEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKEVSSMESIDEHTPLEIRIEYV
                     KAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEEQIGVYETVKGSLMEEEPEKE
                     GEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSDAREEIEKALAKLNKTEGVKE
                     VYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHAFSNEWFVSEKELHASNLQYM
                     PGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLENELR"
BASE COUNT          628 a          279 c          352 g          482 t
ORIGIN      
        1 atcaatcgta tgatcgatca aatggagtct gtcaaaaaag aaagttattt ggaccctact
       61 gtttttgaag cagaggaaca tatccaaaaa gtcattcata aaatgttccg tccagacaat
      121 gcctatacaa aatttgattt tcgaaatggc cgtccaacga agtctgcgat cttaaccacg
      181 agttccattg atatggccaa aaagtattat cgggccatca aagagatgac gaaagaatct
      241 gattggttaa taaaagagtt tcccaatcag cctatccgtg aaggacgaac gatggaggat
      301 cctgatttcc cacgaatcgc tattacctat tcattagaag aaaatagccg agattcaagt
      361 gcccaacaag aagaaatgca aaaaattatt gaggaatata atcagtatta tgatactgcc
      421 tggtcactag cagacattga gcgttataac ggagacatca ataatcgttt ggcacgaaaa
      481 agagcggaat tcaaacaatt tgggaaacaa atcgatttag taatcgtagt ggatcgtcta
      541 ttgacaggtt ttgacgcccc tacgattcaa accctatttg tggatcgtaa tctagagtat
      601 gcaggattga tccaagcctt ttcacgtacg aaccgtacgt atcctgaaaa aacaaaagga
      661 ctaattgtta ctttccgaaa gccagcgaca atggagaaga atgtcgagga tgcgacaaaa
      721 ctgtattcag aagctaaaga agaatcgggt ttgatttatc caagttacca agaatccaaa
      781 aaaagattca agcaagcata tggtaagtta aaagaggttt catccatgga atccattgat
      841 gaacatacgc cacttgaaat ccgtatcgag tacgtcaaag catttcaaga attgaatcgt
      901 gcgtatgaat cgttagtgac ttatgatgat tacaatgatg acatggtgca atcttcaact
      961 ttgaacaatc aaattcaact tttggaagaa caaattggcg tgtacgagac cgtgaagggt
     1021 tcattgatgg aggaagaacc agaaaaagag ggagaagatt tttcaacgat cgaattttat
     1081 agtgaaaata ccactaagtt gtatgatatt gattctactt atattgatca attactagga
     1141 acttatgctg cgaatagttc agatgcacga gaagaaattg aaaaagcttt ggctaaattg
     1201 aataaaacag aaggagtcaa agaagtttac cgacaaattt taaatgcatt tgatgtgggg
     1261 actttagata gtaatgaaga tatctttgtc attaaacgtc gctattttac acaagcaagt
     1321 gataatttga ttcatgcctt ttccaatgag tggtttgttt ctgagaaaga attacatgct
     1381 tctaatctgc aatatatgcc aggtgaagat ccaattccta atatgaaagc aattatcaac
     1441 agtaaggatt acgaaggata taaagccaaa catccagaag cgaaaccatt taaataccca
     1501 caagaaatga agcgagcatg gcgtaaaatg ttagatgatg agttgattcc acttgaaaat
     1561 gaattgaggt aaacgagaag agttaagaaa attgtacgat tcaaagatag tagtaaagtg
     1621 gaagtgtaga aaatagggat agatgtcttt ttacttgttc acattttata acggagtatt
     1681 taagaaagct attgaataat gattcttcca tctttttcat tcatttaccg gttctgttgc
     1741 a
//
LOCUS       DADVXV010000190         1607 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.198, whole genome shotgun sequence.
ACCESSION   DADVXV010000190 DADVXV010000000
VERSION     DADVXV010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.198"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..743
                     /locus_tag="KB969_002929"
     CDS             <1..743
                     /locus_tag="KB969_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBB6870831.1"
                     /translation="KYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNI
                     KDSFWNIVTGIVNSAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLIN
                     GVKEKWNALKDTIKGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQS
                     KLDQTMTNLVKTPSVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVR
                     KITTKIKTELTRQMKRDAGAVGGTLYAT"
     gene            733..1473
                     /locus_tag="KB969_002930"
     CDS             733..1473
                     /locus_tag="KB969_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBB6870832.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
BASE COUNT          618 a          188 c          295 g          506 t
ORIGIN      
        1 taaaatataa tgccattact acttggaata atattaaaca gtttttcaaa gatacttgga
       61 aaaatattaa agatacggca tacaatacgt ggatttctat aaaaaatacc atgattaata
      121 catggaataa cattaaggac tctttctgga atattgttac tggaattgtt aattctgctg
      181 aaaatgcatg gacaaatcta aaaaatggtg tttcaaatgc tattaatcgg gtaaaagaaa
      241 tctttaattc gttaagggaa gtcaatttat ttgaaattgg caagaacatc attgatggac
      301 ttataaatgg tgtaaaagaa aagtggaatg ctttgaaaga tactatcaaa ggtattgcag
      361 gtaatatcaa aaattggatt aaaggagctt tagatattca ttctccatca agatggatgc
      421 gtgatatggt tggtaaaaat attgttcaag gtattatcgt tggtattgat aaagagcaaa
      481 gtaagttaga tcaaaccatg acaaatttag taaaaacacc gtctgttcaa cctgtagtaa
      541 atggaataag tcacctacca attacacaaa caaagcaaaa tatatctgct agtgaaacaa
      601 aagaaattca tttacattta aatgtttatg gagatttacc tgattcaatg gttcgaaaga
      661 ttactacaaa aattaaaaca gaattgacaa gacaaatgaa acgagatgct ggtgcagtag
      721 gaggaacatt atatgcaact taagagagga caatttttta ttaatcaaca ttattcttct
      781 gaatttaatg tgtatattca aaacaggcct gcttctgttt cagctagtcg agtaattgaa
      841 ttgagagagc gagaaggaaa tgattctatc attattgata aaggctatta caaaaatgtg
      901 actagaaaga ttgagtgtta ctataaagca ccttcaattg atatggtgca ggagtgggaa
      961 gatcgaatca ctgaatggtt agatatgtcg tcttatagtg attttattct ttactatgat
     1021 gaacaatata tttatcaagc tgtagtaata gaaggacctg aatttaaagg aacaagaaaa
     1081 acaggaaata ttgtcccttt tgaatttaca gtgagtattc gaccatttaa ggaaaattac
     1141 aatggtagat ttactattcg acaaacagaa acttttgaaa tttataaccc agagaagtat
     1201 tcttcaaaac cgcttattaa attgagtggt tctggagatg cttcttttta tattaataag
     1261 gataaatatg atttgaaatc gttggacaga gaattattta tagattctaa attagaagag
     1321 gcttatcgaa aattagatgg taatttagaa catcaggatc aggtcacctt atttttagat
     1381 tttccatttt tatatcctgg aaaaaatgaa attaaatgga cgaaaaatat tcattcattt
     1441 gaaataatgc ctaggtggtg gagaaaagta tgaaaccaag aatatatagt cctactgaaa
     1501 cagatttctc aacgaatggc ttaggaattt taaaggattg tacaagatgt gaaatatatg
     1561 aagtagctaa tggaaaatat gaattagagt tggattatcc tttagga
//
LOCUS       DADVXV010000191         1589 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.199, whole genome shotgun sequence.
ACCESSION   DADVXV010000191 DADVXV010000000
VERSION     DADVXV010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1589
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.199"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            144..542
                     /locus_tag="KB969_002931"
     CDS             144..542
                     /locus_tag="KB969_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBB6870833.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1220
                     /locus_tag="KB969_002932"
                     /pseudo
     CDS             526..1220
                     /locus_tag="KB969_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
BASE COUNT          605 a          231 c          310 g          443 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcagcgataa
     1081 cgttaggtaa agagctacta gatcaagtat tagagatgcc ctcgattgat aaagcagtga
     1141 ggggcttcca agaagattgg gtgcaaactt tccaagcaga aacgattggt gaactaaaaa
     1201 aggtcgctga ttacttctga atcaatttct ccataaaata aacgatagcc ttctcgaaaa
     1261 ctcgaggagg ctatctgacg attcaatatt cattaattta aagtttgggt gactattact
     1321 aactattact tatttctcat ttaaacgatg tattccctaa cctctaatac atccttgtaa
     1381 ctctgaagtt acgccagttt tgaataaatt tcataaaaac aaatgaaaag tgtcgcataa
     1441 aaatatcttt cgtgtttctc tagtataaca gaataagaag aacaagtcca gaagggatat
     1501 ttttagtctt ttttaaaata acttttcagt cgagtttgag tttatgatag ttgtttttga
     1561 agcgatacgg caagtgaaaa aatagggaa
//
LOCUS       DADVXV010000192         1541 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.200, whole genome shotgun sequence.
ACCESSION   DADVXV010000192 DADVXV010000000
VERSION     DADVXV010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.200"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            31..1497
                     /locus_tag="KB969_002933"
     CDS             31..1497
                     /locus_tag="KB969_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBB6870834.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          426 a          290 c          326 g          499 t
ORIGIN      
        1 ctgaaaattt aaagaattgg ggtatagatt atggaaaaac agcaagacaa gggcttcttc
       61 gggcagccga agggattgtc aactttgttc ttcactgaga tgtgggaacg atttagttat
      121 tacggtatgc gtgcattact tatctattat atgtacgata cagttgccaa cgggggactt
      181 ggattaccac gagcaacagc attagctatc atgtcgatct acggatcttt gatctacatg
      241 tctagtatcg tcggcggatg ggtatctgac cgagtgttag gagcaaaacg cactgtattc
      301 ttcggtggag ttttcattat gcttggccac atcgtcttgg ctttaccatt tggtgtaagt
      361 acattgtttg tttcgatggc attgattatt atcggaaccg cctttttgaa accaaatgtt
      421 tctggcatgg tcggacatct ttattcaaag actgacttgc gaagagatgc aggattttcg
      481 attttttaca tgggtgtcaa cttaggggca ttattagcac cactaatcgt tggtacaatc
      541 ggtcaagaat ataactatca tttagggttc tctttagctg ctattgggat gttctttgga
      601 ttattacaat acatcatcca aggacgcaag acattagacg gagtgggtac aacaccgccg
      661 aatcctttga caactgaaga acgtaaagga ttcatccgta acttgatcat cgcacttgtt
      721 gttatcgctg cagtattcgg cggggcacaa ctaactggtc atctgacaat tgactttttt
      781 gtcaatacaa tcagtgtatt ggggattatc ttaccgttgt attactttat caaaatgctg
      841 acttcaaaag atgtaactgc tgaagaaaaa ccaagagtat gggcttatat cccattattc
      901 cttgcagcaa tcattttctg gtcattacaa gaacaaggtt catctatctt agctttattt
      961 gctagtgaac gtacacaatc tacgctattt ggtgtaacga tccaagcaag ctggtatcaa
     1021 tcattgaatc caattttcat ctttattctg acaccagtat tcgtaacgat gtggacgaaa
     1081 cttggtgaac gtcaaccatc tacagtagtg aaattctctc ttggactttt atttgcagga
     1141 ttatcgtact tgctattgat gttgccgggt atgctttatg gtacaagtgg aaaagtaagt
     1201 ccattgtggt tgttgggaag tttcttcatc gtggttattg ctgaattgtg tctttcacca
     1261 gttggtttgt ctgtgacaac aaaattagca ccacgagcat ttgaatcaca aacaatcgct
     1321 atttggttct tagctgatgc ttcttcacaa gcaatcaatg cacaaattgc acgcttctac
     1381 acaccgggaa cagaatctgc ttacttcggt attatcggtg cagtagcaat cgtcggtggt
     1441 atcttgctat ttactgtgaa agaaccaatc aaaaaactaa tgggctctat tcattaatca
     1501 atgaacataa aaacaggaat tgcttatttg cagcagttcc t
//
LOCUS       DADVXV010000193         1484 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.201, whole genome shotgun sequence.
ACCESSION   DADVXV010000193 DADVXV010000000
VERSION     DADVXV010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.201"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(140..1288)
                     /locus_tag="KB969_002934"
     CDS             complement(140..1288)
                     /locus_tag="KB969_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870835.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1305..>1484)
                     /gene="tnpA"
                     /locus_tag="KB969_002935"
     CDS             complement(1305..>1484)
                     /gene="tnpA"
                     /locus_tag="KB969_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBB6870836.1"
                     /translation="FINAYKSASSRLIKRDFPRVKQFLWKEMFWSKSFCLLTTGGAPI
                     DVIKKYIQNQGNNHK"
BASE COUNT          432 a          263 c          237 g          552 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcagatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgccaccagt tgtcagaaga
     1381 caaaaacttt tagaccagaa catttctttc caaagaaatt gtttgactct tggaaagtca
     1441 cgttttatca atcttgagct ggcactttta taggcattga tgaa
//
LOCUS       DADVXV010000194         1480 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.203, whole genome shotgun sequence.
ACCESSION   DADVXV010000194 DADVXV010000000
VERSION     DADVXV010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.203"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            64..972
                     /locus_tag="KB969_002936"
     CDS             64..972
                     /locus_tag="KB969_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBB6870837.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1480
                     /locus_tag="KB969_002937"
     CDS             972..>1480
                     /locus_tag="KB969_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870838.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          529 a          197 c          316 g          438 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt
//
LOCUS       DADVXV010000195         1452 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.204, whole genome shotgun sequence.
ACCESSION   DADVXV010000195 DADVXV010000000
VERSION     DADVXV010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1452
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.204"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(113..259)
                     /locus_tag="KB969_002938"
                     /pseudo
     CDS             complement(113..259)
                     /locus_tag="KB969_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            498..1190
                     /locus_tag="KB969_002939"
     CDS             498..1190
                     /locus_tag="KB969_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6870839.1"
                     /translation="MNKKIVVSGLIIGGLVLAGIAGKNFADDILLWGGEDNIEQINHN
                     LESLDKALENKEQNISSLNSRLSSNNQELEQAKANVEEYKQKVLTLENDKNQLTIEKT
                     NLENQLSGKNAELQGKQNEINAKIDEINQKIAEINQLNTDWNNRLQTEQNKFNDAQNT
                     VNSLNQQINQLSNEKNTIKNQLQSTEQKLEKAQSENSNLNNYIEKLEKAKSDVEDTAN
                     RSQEIVTEHTGK"
BASE COUNT          573 a          203 c          248 g          428 t
ORIGIN      
        1 aaagaatgaa atccattatt atctagtcta gtccattctt tttgtttgca gtatttgtga
       61 tggctttccg tacccttagc tcagttggtc agagcagacg gctcataacc gtccggtcgt
      121 acttctcgta atccaggaag gccgtcagct ccgtccgcag tagcgtgttt acggccagct
      181 ccagatggga gcggaataac tcgttcaaat cacctttggt ggctagagtc tgcaggagtt
      241 ctgtaataaa atcgttcata gggaagtcct cttttctgtg aatgggtgtg gtaactttat
      301 tctacagaag ggacttcctt ttttctattt acacaaaata ttttatactc tcaaatgttt
      361 gtatgcagtt acatctgact ttattcgaat taaggaaaag atttataaaa ataaaataaa
      421 aaaatatata tttaaattga cttattgtga aatcattaac tataattagt tcagtttatg
      481 ttaaggagaa tgatgatatg aataagaaaa ttgtagtaag tggattaatt ataggtggat
      541 tagtgttagc agggatcgca gggaaaaact ttgccgatga cattttgtta tggggtggag
      601 aagataatat tgaacaaatc aatcataatt tggagtcatt agataaagca ctagaaaata
      661 aagagcaaaa tattagtagt ttaaattcac gattatcttc aaataatcaa gaacttgagc
      721 aagcaaaggc taacgttgaa gaatataaac aaaaagtgtt gactttggaa aatgataaaa
      781 atcaattaac tatagagaaa acaaatttag agaatcaatt atcaggaaaa aatgctgaat
      841 tgcaaggtaa acaaaatgaa atcaatgcta aaattgatga aataaatcaa aaaatagctg
      901 aaataaatca attaaacact gattggaata atcgtttaca aacagaacaa aataaattta
      961 atgatgctca aaatactgtt aatagtttaa atcaacaaat taatcaattg tcaaatgaaa
     1021 aaaatactat taaaaaccaa ttgcaaagta ctgaacaaaa actagaaaaa gcgcaatcag
     1081 aaaacagtaa tttgaataat tatattgaaa aactggaaaa agccaaaagc gatgtagaag
     1141 acacagcaaa cagatcacaa gaaatcgtga ctgaacatac aggaaaatag atgcattttt
     1201 tagtttaaat ttctttaaca aaatagtatt ttgttgctaa ataattttta tttgaatatt
     1261 ctacaatgat atctcccctc aaaatggagg ggaagtacat actgtgataa tctacaggtt
     1321 tattgactga ttaggatgtt attaaaaaat aaaatactaa aatgcatacc cgaatttcat
     1381 acccgaaaaa taaaaaatgc caccacgtac actcttttcg aaactaccta agtagccaag
     1441 aatgtactgg tg
//
LOCUS       DADVXV010000196         1425 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.205, whole genome shotgun sequence.
ACCESSION   DADVXV010000196 DADVXV010000000
VERSION     DADVXV010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.205"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            242..562
                     /locus_tag="KB969_002940"
     CDS             242..562
                     /locus_tag="KB969_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870840.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            580..1011
                     /locus_tag="KB969_002941"
     CDS             580..1011
                     /locus_tag="KB969_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBB6870841.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            1141..>1425
                     /locus_tag="KB969_002942"
     CDS             1141..>1425
                     /locus_tag="KB969_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HBB6870842.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWN"
BASE COUNT          532 a          198 c          239 g          456 t
ORIGIN      
        1 caattgacag tatctgagta atactctata ctaagagcat aattaaataa gacataaaaa
       61 cattgatttt aaagctttct tggcggtctg catttacata tcaatagtgt tttttgttgt
      121 ctttttagtt gttaaatctg tttacaagat atagtatagc tcattactca gaattagtca
      181 aattatttct gcgtattttt ctaaactttt tttgtaaaca tttagaaagg ttgttttatc
      241 gatgaatacc tatgaaataa taaaagactt ggcgaagagg aaaaagatat ctatacggca
      301 gttagaaatt aattttggat attctaacgg ttatctagca aagtggaaaa ataatactcc
      361 taattcagat gaattaagtc ggattgctga ctatttcgat gtctctgtag actaccttct
      421 aggtagagaa gaaagagaaa cccctaaaca tgtggattta tcagaagacg atactgtttt
      481 ttcttttgat ggaaaagaaa tatctaagga gacaatgcgt aaagcgattg caattgctaa
      541 agctttagag gaaaatgaat agttggagtg atggtttgta tgtatttgaa attgaaagaa
      601 atgttgagcg aatacaattt gaaagtagtt tatatggaga tgaaagagcc tggtttctac
      661 tatccaaaac ccagaatcat ttttttgaat gaaaatctat acggtgaaac tgcagaagcc
      721 tttcatttat ctcatgaact tgcacatttc agcgcctctc attttgaatt ttcagttttg
      781 tacgatactt ctacaacttt tcactcaaaa tttgaaacag aagcagataa aatagctatt
      841 ctaattttat taaatatcta tattgagaac gaactgactg atgaatctca gtttaatctc
      901 gaaaaattta tggagtatta ttctattcag aataagctca gatacacttg ttatgctgtc
      961 tgccaatgct attttaagaa aaaatattct tacgcaaggc aatatgtatg aatacatcaa
     1021 gaattattaa aaaaaccgat ttcagcaaaa cattaaaaaa gcccgtgctg caacacgggc
     1081 tctttcctca tatatgagct tctacaaaaa aaatcatatc acagaaatga ggaagaaaaa
     1141 atggaaaaag agattttaat aaaatctcca ggaaaaacct tgattaaagt aactgatgat
     1201 tctatttcaa ttattagaaa aggatttata aatttagtta atcaaggtat taaaggagaa
     1261 aaaactatcc cctttaaaaa tatatcagcc gtacaattaa aaaaaccagg tatgagtaat
     1321 ggttatatac aatttacctt gctaggcgga aacgaaagtc gcggaggtat attagcggcc
     1381 acgaaagatg aaaacaccgt tatgtttaca aaaaaatatt ggaat
//
LOCUS       DADVXV010000197         1408 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.206, whole genome shotgun sequence.
ACCESSION   DADVXV010000197 DADVXV010000000
VERSION     DADVXV010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.206"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            142..>1408
                     /locus_tag="KB969_002943"
     CDS             142..>1408
                     /locus_tag="KB969_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBB6870843.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQ"
BASE COUNT          492 a          188 c          291 g          437 t
ORIGIN      
        1 gggaattatt tggttacgag tcgaggggtt tttgaactaa tgtaaatcat ttgttagaat
       61 tgaccagaaa tttctatcgt acttttactt ttctatttga tatactgaaa tagaaaatat
      121 ttgttgatag gggtgttact aatggttggc aataagtggt acaaatgtga tcttcatatt
      181 cattcaactg cgagtcagtg ctttcaggat aaaaaggtta ctgctaagga atgggtagaa
      241 gaatgtttaa acaaaggact cgattgtgtt gcattaactg atcacaatac aggggaaaat
      301 attgatgaat ataagaaagt ggctatcgaa aatggcttag atttttttcc tggagtggaa
      361 ttaacgtgtg gagaaaatgg aactcattta ctagtcctat ttgataaaag tgcatgtaca
      421 aatgatatct ctgatttctt aaccaagatg ggtataaaaa gagaggattg ggccagcgct
      481 gcagcttgct caatgaaatc agttttagaa gttattgatt ttgctgagca cgagggcttg
      541 ctcgttattc ctgcacatat agatgagttt aatggaattt cttcagcaaa atttggaaat
      601 ctaggaaaga tatttgaatc agaaaatata tatgcagtac agacggttca aaaagaattt
      661 tttgaaaatc gctcacaaat gattccctca tctaagcgtg acactatcta tgatagtgtg
      721 aatgccagat atgatggtag agttggaaaa gatactttgg aatcttggta taaatcagtt
      781 gttgaggcag aaaaaaataa tatgacattt cttagctttt ctgataaccc acactcgaaa
      841 ggaaattcaa aacatggact ttggggaata ggcacaagat attcctatat aaaaatgaag
      901 gacgaacctg acttgggatc acttcgcgat gctttaatgc taggcgaaac tcgagttcat
      961 tctgattttt ctaatttctc cattaatgaa aatgaagttt tattggaaaa attaagcttt
     1021 tctgggacca ctcttagcac aaaagaagtt gtagtcgaat tcagcgataa tttaacttca
     1081 attattggag gaagaggaac aggcaaatct tgtattacaa gattcttggt ctatgtcctt
     1141 ggaaaggaag cagaacttga tcaattttct gaaatacaaa gtgattatca gaactttgca
     1201 caaattgaac ataatggctc tggaatattt ttgaaggata caattgtgaa actgaatatt
     1261 ttctataagg ggacaaaata tcaaataata agaacacagg atagacattc tatttatgaa
     1321 tttacacaag agaatggtct ggttgaaaaa gaaacagaac ggttgagaat gatttccgat
     1381 aaggtgagta tatactctca aaaacaaa
//
LOCUS       DADVXV010000198         1376 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.207, whole genome shotgun sequence.
ACCESSION   DADVXV010000198 DADVXV010000000
VERSION     DADVXV010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.207"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            157..1029
                     /locus_tag="KB969_002944"
     CDS             157..1029
                     /locus_tag="KB969_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBB6870844.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          438 a          235 c          313 g          390 t
ORIGIN      
        1 tatgaaaaat tattagaatt ttaaaaaatg ataaaaattc aaaaagaaaa aatagtagtt
       61 atttacttgt catgttacta aataaaaaaa taatttaaat atgatatata gtcatttatt
      121 tagtgatttc attctaaaat aaagggagaa atgtctatgc tatacggtgc aattgaagca
      181 ggcggcacaa aatttgtgtg tgccattggc gatgaagaaa tgacgatcaa ggaaagagtg
      241 agctttccga caacgacacc tgaggaaaca atgcctttag tcattgactt cttcaaacaa
      301 taccaagcag atttagcagg gattgggatt ggctcatttg ggcctatcga tatccatcgc
      361 gattccgcca cttatgggta cattacctcg accccgaaat tggcatggca aaattttgat
      421 ttcatcggta ccatgaaaaa agaatttccg atcccgattt cttggacaac agatgtcaat
      481 gcggctgcct atggtgagta tgtcttcggc agtggcaaag gattgagcag tgtcgtttac
      541 tatacgatcg gtacgggtgt tggcggcggt gccttacaag aagggcgctt tatcgaaggg
      601 tttagtcatc cagaaatggg gcatatgctc gtcgtccctc atccaaaaga tgactttgct
      661 ggcagctgtc catttcatgg caactgttta gaagggatgg ccgctggacc cgccatcgaa
      721 aaccgcttag ggaaaaaagg acaagaggtt gcagaagatg atccttattg ggaaatcgaa
      781 gcctcctata ttgctcaatg tgcctacaat acaaccttga tgttttctcc agatgtgatc
      841 atttttggcg gtggtgtgat gaaacaacgc catatgctgc aaaacgtcca cgacgcattt
      901 gcaaaattgg tcaatgggta tgtcgaaaca cctgagttaa gcaaatatat cgtgacccca
      961 gcattagaag acaacgctgg aacgctcggt tgtttggcat tggctcgaga agcggtctta
     1021 cattcataaa cgaaaaaagg ctcttcgaca tttagtgttg gtagagaaag atacaactga
     1081 aaatttagtc ataaccagtt aggcagagtg cttaactggt ttttgtttta cttggaagat
     1141 caagccttga atgagataaa ttcttgctcg aaagttatgg aaatttcgat agccgtaggc
     1201 cacttgtatt gtgcaatagt tttttacaaa aaaaaggggg tgcggatatt tttttggacc
     1261 tttttaacaa ataggttctg ttgcaaagtt ttaaatctac tatcagataa ggtagaataa
     1321 tagaaaaaga tagcaggagg aatgacgatg agtcatttta aaggaaagca atttca
//
LOCUS       DADVXV010000199         1355 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.208, whole genome shotgun sequence.
ACCESSION   DADVXV010000199 DADVXV010000000
VERSION     DADVXV010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.208"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..1355
                     /locus_tag="KB969_002945"
     rRNA            <1..1355
                     /locus_tag="KB969_002945"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DADVXV010000200         1336 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.209, whole genome shotgun sequence.
ACCESSION   DADVXV010000200 DADVXV010000000
VERSION     DADVXV010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.209"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            33..>1336
                     /locus_tag="KB969_002946"
     CDS             join(33..474,474..>1336)
                     /locus_tag="KB969_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBB6870845.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGL"
BASE COUNT          562 a          170 c          233 g          371 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggacta
//
LOCUS       DADVXV010000201         1316 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.210, whole genome shotgun sequence.
ACCESSION   DADVXV010000201 DADVXV010000000
VERSION     DADVXV010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.210"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            24..1292
                     /locus_tag="KB969_002947"
     CDS             24..1292
                     /locus_tag="KB969_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBB6870846.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT          324 a          236 c          318 g          438 t
ORIGIN      
        1 tttttattga ggaggaattt tttatggaaa aacaattacc gagtccagta cgcattttag
       61 tgtacatgct gaagtggctg gtgatcacag cgattctcgg tatattcatg gggagcttat
      121 ctgctttttt cttaaatagc ctgacagttg tgacagatat ccgactatca catccttggc
      181 tcctttatct actaccagtt agtggtgcgc tttttgctta tctctatgcg tatcacggcg
      241 gtctttctag tcgtggaaac aacttagtga tcgatcaagg aaatggtgga gaagaaaaaa
      301 tcccgttgcg acttattcca cttacactgt ttggaaccat aactacccat ttatttggag
      361 gatctgttgg ccgtgaagga acagcagtcc aaatgggggg agcgttagca gataatacag
      421 cacgtttgtt ccgattggat aaatcagaac gggaaatctt gattatcagt ggaatcagtg
      481 cgggttttag ttctgtattt ggcacacctt tagctggaac attatttgga ttagaagtgt
      541 tggcaatcgg gaaagtccga acagaagcga tcttccctag cttctttgct gcactgtttg
      601 caaattttat gacagaaagc tatggtgttt ctcatctaca ttaccaaatg ggtgtgattc
      661 ctgaatggag tatgttgctg ttcttcaaag tttttgttgc tgggattgct tttggtttga
      721 ttggttgggt attcagccgt tcgatcgtct ttttaaaagc gcgatatgca caatggattc
      781 ctcatcctgt ttggcgaaat acgataggtg gggctgtagt tgtagccgca gcattgattt
      841 tgcaaacaca acgttatctc ggattgagtc ttccattact gcaggaatca tttaatggac
      901 aggcacatgt ctatgatttt attgggaagt tattcttcac agttttgtct ttaggcgcgg
      961 gatatcaagg gggagaagtg acaccattgt ttgaaattgg tgcaacgctt ggtgcagcac
     1021 tagcgccttt gctccatgtt tctgttcctt ttcttgcagg attgggcttt atcggagtat
     1081 tttctggtgc gacaaataca ccgattgcct gctttgtgat ggggatcgaa ttgttcggtt
     1141 cacaagcggc agtatacttc tttatgatct gcttgatcag ctttatgtgt tcaggcaaca
     1201 gcggtattta ttctgctcag caagtagcgg tcagaaaagg gatactcttt ttgccaatag
     1261 ttaagagaat gaaagaaaaa aacaaggtgt gacatatgtt ttgtcacacc ttgttt
//
LOCUS       DADVXV010000202         1247 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.212, whole genome shotgun sequence.
ACCESSION   DADVXV010000202 DADVXV010000000
VERSION     DADVXV010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.212"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            104..364
                     /locus_tag="KB969_002948"
     CDS             104..364
                     /locus_tag="KB969_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870847.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(726..965)
                     /locus_tag="KB969_002949"
     CDS             complement(726..965)
                     /locus_tag="KB969_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870848.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT          440 a          169 c          224 g          414 t
ORIGIN      
        1 tttttatttt tttataaaat cacaagtgtt attgattttc ataatcatat tttaatggta
       61 ttatcatttt aaataatgga aaaacattaa ggatggatga aatatgaata acgaaactat
      121 cattttagga aaaaaatata tttgccaacc tattggcttg aaacaaaaag tggttggaga
      181 agtaatcagt aaattagaaa attgtgttgt gatctgcgta gacgaatatc atgacgtcga
      241 tcgcaatgaa atattagaaa aatgcggaaa agtagtggca aaatatactc acgtttatga
      301 gttggaaaca acagaatatc tatataacta tagcaacaaa tatgaacata ctttagtttc
      361 ataaagattt aaataaagtg ccttcaaaag cgagaagacc aagcttttga aggcacttta
      421 tttagttggc agtgattgtt catgattttt gatttattca aaaggttcgc ctagagaatc
      481 tgtctctgta acgaggcctg gtggagaaac tcgataaaaa cctatactgc cagaactgtc
      541 ctattttcgg atagacaaac tagtagtttt aaaaagatca tccgatccaa tcatttcaaa
      601 aaatgcaaaa ctgatatcag gatcatttag ctcaggcttg ttatcgtaaa gcatttgtaa
      661 aggttgcatt tagttaggag taaacgcgaa actatcatca ttatttgctg aagaagatga
      721 agaagctaat tcagagtttg tttgaaataa aggagacgtg ctgacagttt ctttaccctg
      781 ttttttgcag aggtagaaac ttttatatcg gaagtttcta ccggagaatt tttctcattt
      841 gtagaaattg ttgaatcgat actattcgaa atttgcgtat ctgaaggtat gttctttgat
      901 gcagaagtcc cacaagcagt aagtaacaat aaatttgata aactgataaa cagaattctt
      961 ttcattatgt acacactcct tatagtatcg tttagcatac acctatgctc agtattaggc
     1021 aaaatcaatg caaaactatc aagtctttta tagtatctat tagtcttagt aatacatata
     1081 tggagagggt gatatcccag ttcaaaccag atacattggt taccatctgt attaacgatt
     1141 atgcctctaa acgctttttt tatgaaaaaa tttataagtg aaaacgtagg tatgatatta
     1201 tctagaggta atttttttgg gtatttaaat agttgctagg aggatag
//
LOCUS       DADVXV010000203         1246 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.213, whole genome shotgun sequence.
ACCESSION   DADVXV010000203 DADVXV010000000
VERSION     DADVXV010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.213"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            200..742
                     /locus_tag="KB969_002950"
     CDS             200..742
                     /locus_tag="KB969_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870849.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="KB969_002951"
     CDS             898..>1246
                     /locus_tag="KB969_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBB6870850.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DADVXV010000204         1244 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.214, whole genome shotgun sequence.
ACCESSION   DADVXV010000204 DADVXV010000000
VERSION     DADVXV010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.214"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(60..278)
                     /locus_tag="KB969_002952"
                     /pseudo
     CDS             complement(60..278)
                     /locus_tag="KB969_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(544..738)
                     /locus_tag="KB969_002953"
     CDS             complement(544..738)
                     /locus_tag="KB969_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870851.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(838..924)
                     /locus_tag="KB969_002954"
                     /pseudo
     CDS             complement(838..924)
                     /locus_tag="KB969_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          441 a          210 c          170 g          423 t
ORIGIN      
        1 ggtattttta ttatatatag atttaacata tgtcggtcgg ttgattgata tagctaaagt
       61 tataactcaa ccgaagccga ttcatctaca cgaataaagt tgcgagtgtt ctcggctaat
      121 tcataaaaat tgttatgtgt tccatatagc aatactggaa taactttatt ttcttgaatc
      181 tcataagcaa ctctatacac ggtgaccgca tacttaaatc cattagacca attacctgat
      241 aaacctccag ttttttgctc ttacttaaat ggatcaatgg caatttcatc acaaacctat
      301 agaggatgag tgacttctgc ctaattacgt taaaaaatat tgaaagtaac tctatgtagc
      361 aaaaaatatc tagaatttca tttcctcaaa actgatcgat attgtatcta aaaatatata
      421 ctacctaaaa taggtagtat atattaaaat atgtgctttt gttagaaaaa tcaatacata
      481 aattatcata tctgtatatg tcatttaggt atttcagtta tgttataata gttttgctgt
      541 ctgctacccc ggcctaatct ggcaagggga ggaggagata taatgaaata cctttttgat
      601 tttgtttttg caatcaagcc acttgcagat gtagtgtgca gttacctctg caaatggctt
      661 gattgcaaaa ttgccaaaaa agacagtaag cctacccgtt aattctataa tatagaaacg
      721 taaaaaaaac cccatcagcc tgcacgctga tggggtttgg tgatataatg aaatacctct
      781 ttgttactca taattatacc ataattagtc acgaatgcaa ccaatagaaa aaactactta
      841 gaacggtaga tcatcgctaa taacaatgca ttgtccacca aatggatttt gtgaagcatt
      901 aaatacattg ttattaattg tcgctgcttt taactaggcc tctccccttc tattataaaa
      961 gaagatatat atcatttctt aattacctac taccttaaac caaaatttaa gtactaccta
     1021 atttaagtag tacttaaaca atctaaaaaa tagttatccc aattgttatg cttttataat
     1081 acgattattt gtaacaaaat gaatattata taattaaaca ctaccatatt taggtagtgt
     1141 ttaattatta gcaaaacaaa aaatatttat tctattctct taacttcaac taagttatgc
     1201 tgcacacctt tatataaatc atatgcaact cattagctag acaa
//
LOCUS       DADVXV010000205         1238 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.215, whole genome shotgun sequence.
ACCESSION   DADVXV010000205 DADVXV010000000
VERSION     DADVXV010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.215"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            78..>1238
                     /locus_tag="KB969_002955"
     CDS             78..>1238
                     /locus_tag="KB969_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBB6870852.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIY"
BASE COUNT          412 a          243 c          239 g          344 t
ORIGIN      
        1 taggtattaa aaaacatatc gttctctagt atgattaaat caccacaaaa taaacaactg
       61 agaggacgat acgctatatg aatgattcta tcaaaaaaat gctgagaata acagagaaag
      121 atttgatgat tacagaggtc tcttacgaga cccttcagaa gaaaaagacg ttggtcgtcg
      181 atgctgttct ctcgcctact cctcgtgctt gtagaagttg tggttctact gtggtagatg
      241 gaaacgggaa agcaattata gtgaaaaatg gaaaaaagga aacgattgtc cgttttgaac
      301 aatacaatca tatgcctttg gttatgcgcc taaaaaagca acgctatacc tgtaaaaact
      361 gtcgcaccca ttggacggct caaagttatt ttgtccaacc cagacattca atcgcaaatc
      421 atgttagata taaaattgct tctttactga ctgaaaaagt atctttatct tttattgcga
      481 aaagctgtca ggtatctttg accaccgtta ttcgtacatt gaaagagttt aaaagctatt
      541 taccaaagca atctaagaag atcctcccca gagtattgat ggttgacgaa tttcgttcgc
      601 atgcttccat agaagataag atgagcttta tttgcgcgga tggcgaaaca ggaaaattaa
      661 tagatgtttt gcctacgcgt aaattacctc gattaacaag ctatttctta ggttgtacca
      721 atccagaaga agtagaattc ttggtgacag acatgaacgc cgcctacttc cagctcacca
      781 aacgtgttct gccaaatgcg aaagtcgtga ttgatcggtt tcatattgtc aaacacatga
      841 atcaagcgtt caatgagttg cgtatccgtg aaatgaatga acttcgtaaa gccggacaga
      901 aaagccaggc agaaaaactg aaaaagaact ggcgcttttt gctaaaaaat cgtgcaaaca
      961 tcaaccatta tgaatacaaa acatggaaaa gtttccgagc accaaaatac ccatttctta
     1021 ctgaagcaat gatgattgat cgattgcttg agttttctcc gcccctaaag gaggcgtatc
     1081 ccttttttca tgaattagtt gaagcctttc gagacaaaga ccctgactta tttttctcct
     1141 tattggcaga acttcccgaa acgttagatg acagctttcg ggaaaagctt caaaaccttc
     1201 tgacctatga agaaggcatc accaacgcaa tgatctat
//
LOCUS       DADVXV010000206         1219 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.216, whole genome shotgun sequence.
ACCESSION   DADVXV010000206 DADVXV010000000
VERSION     DADVXV010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.216"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..460
                     /locus_tag="KB969_002956"
     CDS             <1..460
                     /locus_tag="KB969_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBB6870853.1"
                     /translation="LLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            469..696
                     /locus_tag="KB969_002957"
     CDS             469..696
                     /locus_tag="KB969_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870854.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          377 a          195 c          204 g          443 t
ORIGIN      
        1 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
       61 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
      121 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
      181 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
      241 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
      301 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
      361 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
      421 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
      481 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
      541 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
      601 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
      661 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
      721 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
      781 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
      841 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
      901 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
      961 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1021 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     1081 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     1141 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     1201 cattattttg ataataatg
//
LOCUS       DADVXV010000207         1195 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.217, whole genome shotgun sequence.
ACCESSION   DADVXV010000207 DADVXV010000000
VERSION     DADVXV010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.217"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            98..>1195
                     /locus_tag="KB969_002958"
     CDS             98..>1195
                     /locus_tag="KB969_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase"
                     /protein_id="HBB6870855.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAG"
BASE COUNT          391 a          176 c          209 g          419 t
ORIGIN      
        1 aattatattg ttgataaact ttttcctaca gcaatttaat aaacgtcttt aatatttaag
       61 cttaataaaa agataaaaca agtcaggagt tgcaaaaatg gaaagaactg ctcggctcaa
      121 aaaaaacact atttgggctc tggtgtttca aataacttct attgtctgtg gtatgatctt
      181 gctacgtttg atattaacaa agtacggatc cgaggttaat ggaatgatta gctctattaa
      241 ccaatttcta caaattattt cttttttaca attaggagta ggcgctgtaa tgcaatcaac
      301 tctatacaaa ccactagcag aaaaggataa tttaatgata agtcaaatct tagcttctgg
      361 agggaagttt tatcggcaaa ttgcatatat tctactagta tacgtgggtt tgttacttgc
      421 agtctattat gttctcgttc ctaatgaatt tgggagatca tatacaatgg caatgattgc
      481 aacattaagt attaattcat ttgctcaata ttattttggt attgttaata ctttgttatt
      541 aagtgctgac cagaaaattt atattacgta tattgcacag acaatagcat ttatttctaa
      601 tacagttgca tgtgctttat taattagtct gaacacagag atccttatgg taaaacttat
      661 tactgctata atttatcttg cttgtccaat atattataga tggtatgtgg atcgaaacta
      721 taatataaag aggaatgtgt catatgataa ggaaccgatc cctcaaaaat ggaatggggt
      781 tgcacaacac gtagcttctg ttgtactaga tagtactgat gttgtagtgt tatctatatt
      841 ttctaacctg atatatgtat ctatatataa tgtgtacaat ttagtaatat acggagtaaa
      901 acagctattc atggctatga caaatggcgt tcaggcctta ctaggggaac tttgggtcag
      961 aaaagaaata gaagttcttt acaaaacatt tgcatggttc gaatggattg tacatacttt
     1021 gacagttttt atttttggct gtaccggtat actaatcgtt ccatttattc aagtatatac
     1081 aagaggagta acagatgcta attataatca attatcattc gcagctttac ttgtaactgc
     1141 taacgcactt cactgtctgc gtacacctta tcatgtaatg ataaaagcag ctggt
//
LOCUS       DADVXV010000208         1152 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.218, whole genome shotgun sequence.
ACCESSION   DADVXV010000208 DADVXV010000000
VERSION     DADVXV010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.218"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..193)
                     /locus_tag="KB969_002959"
     CDS             complement(<1..193)
                     /locus_tag="KB969_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870856.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEAR"
     gene            complement(210..>1152)
                     /locus_tag="KB969_002960"
     CDS             complement(210..>1152)
                     /locus_tag="KB969_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBB6870857.1"
                     /translation="NIDKVFFKLKMNNLNVAMADRERLYNSLQNLTLYSLGDIRDILI
                     LVHYFFTGKIEDLFHEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLYENKILEY
                     VKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLGMDIIEAY
                     QSRDALIQENELAVSLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQFIGLNIY
                     KRITVKEIANYFSVSETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNHTISEVSL
                     GLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFNNIS"
BASE COUNT          396 a          200 c          128 g          428 t
ORIGIN      
        1 ctctagcttc ttcacataaa ctttttactt tattaattac tactttgtca tattcattta
       61 acacactatt attaccatta cttagacgct cagattctac gaaacaactc aaatcagaaa
      121 tttcccaaaa aaattttttg ttaaaatcca atttcctcaa ctcctccaaa ctacgtaaat
      181 gatatagtct cataataaaa taaaacctct cagctaatgt tgttgaaatt gtccactaaa
      241 cctaattgat attgcttagg agatacacct gcgtactttt tgaatactct cgaaaagtgt
      301 gaagaatctg aaaatcctaa acctaaagaa acttcactga tagtatggtt tgatttcaac
      361 attattttag ccgtagaaat ttttcgctta gagatataat tataaatcgt aatatgcatt
      421 tcattcttaa agctttctct taatttagtt tcacttacag aaaaataatt agctatttcc
      481 tttacagtaa ttcttttata gatatttaag ccgatgaatt gaacgacaga agaaattaag
      541 ggagaaagat gctctatctt agtttttccg atttccttag tataataaac aatcccagaa
      601 tccctcactt ttaagacctc aggtaacgat acagctaatt cgttttcttg tatcaaagca
      661 tctctacttt gatacgcttc tattatatcc attcctaatg ttatagacgt ttgtgctaac
      721 ttttcaaaaa caatgataga ataatttttt tcagaccgaa tcgtatctcc actaacactt
      781 ggaattattc cattactcag attaaaaacc atgttttcta aatttcgaat atctccattt
      841 ttaacatatt ccagtatttt attttcataa agaaacagat atatttctgg atcgtaattt
      901 tgtgataaca gattatctat tttgatttgc tcgatagttt tacttagatt ttctgtatat
      961 tcaattaacg gttcatggaa tagatcttct atttttccag taaaaaaata atgaactaaa
     1021 atcagaatat ctcgaatgtc tcctaaagaa tacaaagtca aattttgcaa tgaattatag
     1081 agtcgttctc tatcagccat tgcaacattc aaattgttca tttttagttt aaaaaaaact
     1141 ttatcaatat ta
//
LOCUS       DADVXV010000209         1069 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.221, whole genome shotgun sequence.
ACCESSION   DADVXV010000209 DADVXV010000000
VERSION     DADVXV010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.221"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..969
                     /locus_tag="KB969_002961"
     CDS             <1..969
                     /locus_tag="KB969_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBB6870858.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DADVXV010000210         1063 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.222, whole genome shotgun sequence.
ACCESSION   DADVXV010000210 DADVXV010000000
VERSION     DADVXV010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.222"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(38..994)
                     /locus_tag="KB969_002962"
     CDS             complement(38..994)
                     /locus_tag="KB969_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870859.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          380 t
ORIGIN      
        1 tttagaaaaa gcagtcggac tttctaaaag aagttcacta ttcgatcctg tcgatgattt
       61 cttcaggaaa atcgtctatt tgcttgtcaa ttttgctgtc tttgtatttc tcttcttgga
      121 tagtcaacaa aatctttgta agattccccc agtctactgc tcttggcgga tcgagccaaa
      181 ccactacttg agatgcactt tcttcatata gattattcct attcgtgatt ataacatccg
      241 ggaactcagg ctttcctgcc tctatcactt ccgtgttcag attaatgtac aagcttaaat
      301 ttttcttgat aaattgatta taggcagcac cataagaaaa atcgatgatg atctttactg
      361 gttcagaaat cagttgaatg ggtatgtgat tgatcaataa taataaataa ctgaaaaaaa
      421 gaaaaaattt atcttgaagc aactctttgc gttttgacgt tagatcattt atatactcta
      481 tcaaatagca ataaaatgct ggatagtttt ctctaaaaaa agaaacatca agtggaaatt
      541 catcagcttt attaatagtg taatgcaaaa gtttaaaatg tattttggtt aactctcttc
      601 ggatcaattg gctcgtctct tctcgcaaca gattaaactg attttcaaaa ctttcaatga
      661 atcgttcatt caaccattcg attgtttcat cttcattttt tctcaagtat ttttgatcca
      721 atttatcatg aagataaagc caagagagtg tcttattgat aaaaataacg gatttttctc
      781 ctaatactcc ttttaagtgg taaaatccta tatccgaaaa aaatagcgac tgattgctag
      841 caatatctaa agaatcagct tgttcagcca acaggttgat tgctaaaaag tggaataatt
      901 tctttttttc ataagcagac agaggataat actgttttaa atcttttaac attttttctg
      961 tttttataat tataggtagc gtatacaatt ccacaaaact tatctctgtt gagttaaaaa
     1021 gattatataa aaaaagccga atgtttttag gattccctgt caa
//
LOCUS       DADVXV010000211         1045 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.223, whole genome shotgun sequence.
ACCESSION   DADVXV010000211 DADVXV010000000
VERSION     DADVXV010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.223"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="KB969_002963"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="KB969_002963"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBB6870860.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DADVXV010000212         1035 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.224, whole genome shotgun sequence.
ACCESSION   DADVXV010000212 DADVXV010000000
VERSION     DADVXV010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.224"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..>1035)
                     /locus_tag="KB969_002964"
     rRNA            complement(<1..>1035)
                     /locus_tag="KB969_002964"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DADVXV010000213         1029 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.225, whole genome shotgun sequence.
ACCESSION   DADVXV010000213 DADVXV010000000
VERSION     DADVXV010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.225"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..1012)
                     /locus_tag="KB969_002965"
     CDS             complement(<1..1012)
                     /locus_tag="KB969_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870861.1"
                     /translation="MLFLSFAYVIPLFMSKGIYHSVNQDTYFHLSRIIGLDNVWSSPV
                     NFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFITFLTMVVSYFSMK
                     QIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLILMGCYEIYIRDYQK
                     WYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLKATVLTFFLS
                     AGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLFLFLGLIGAF
                     IFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNGFSSLFIAYT
                     MSI"
BASE COUNT          431 a          154 c          162 g          282 t
ORIGIN      
        1 ctatactcat cgtataggct ataaataaag aagaaaaacc atttaaccgc cagacaaatt
       61 gtagactctt aactggtgta tggttaaaaa gttgccaagg aaataaattg gttgaacaaa
      121 aaagaacaaa tacaccaaga aagaaaataa ataaatcatc agcagttaat ttttttataa
      181 aaataaaagc accaatcaat ccgagaaata agaataatcc aatagtatag ttgttatagt
      241 tattatttaa aatatgtgtc agcatatcac taggagccat accacttaat tcttttccca
      301 gtgggacttt caattcttgt gctctagatt gttgaataaa aggaattaag aatcccgcac
      361 ttaaaaaaaa ggtgaggacg gtagctttta aaagacttaa gagtctagcg attttttggt
      421 cccaaaaata aaaagaaaga aacaacgttc ctccaataaa tacagaaacc atagcgacag
      481 aaagtaaatg agtatacact actagcgtca tgccaataga caaccagtac catttttggt
      541 aatctctaat ataaatttcg taacacccca ttagtatcaa aggcaaaaat gttaaagcga
      601 cagcttctcc caatgaagca cgatggaata tgtcaatggc acgataggcg gaaaatgtat
      661 aaataatcga aaataacagc gaaatataac gattgttttt tatttgtttc atagaaaaat
      721 aagaaacgac cattgttaaa aaagtgataa aaaaatagta gatattataa cttaaaacaa
      781 gatttcccat cattttataa aataaaaaag ctggataaag agtaagccat ggataaaaaa
      841 tattcatcat tgttccatga tgatcgaagt tattgaagtt tactggagaa ctccatacat
      901 tatctagtcc tatgattcga gataaatgaa agtaagtatc ctgattgaca ctatgataga
      961 ttcccttaga catgaataga gggatgacgt aagcaaaact tagaaataac ataaaaatga
     1021 tatctatta
//
LOCUS       DADVXV010000214         1027 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.226, whole genome shotgun sequence.
ACCESSION   DADVXV010000214 DADVXV010000000
VERSION     DADVXV010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.226"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..561
                     /locus_tag="KB969_002966"
     CDS             <1..561
                     /locus_tag="KB969_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBB6870862.1"
                     /translation="PVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTI
                     WKAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVL
                     VSSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLF
                     NKRDVISIVFWYYLGSISYLYLKKEN"
     gene            563..>1027
                     /locus_tag="KB969_002967"
     CDS             563..>1027
                     /locus_tag="KB969_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870863.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKK"
BASE COUNT          366 a          121 c          170 g          370 t
ORIGIN      
        1 cctgtatcga ttgatagaaa agtagaagtt atagagtcaa atgaatcaga taaaactcca
       61 cttccagaaa aagaagtaat attacagcat tctagtgata actccgaaat ttcagctggt
      121 cgttttacga tttggaaagc tgcgcttaaa gttataagac caactttgtt atttggttat
      181 ggagagaccg atttctatgg gaatagcgat gcaaaatttt tgaaaaaagt agatcttgat
      241 actacagatg tgaatgaact aaaaagagca catggaaaca tgcataatgg atttcttcaa
      301 gtacttgtat caagtggtat aattgctttt atatgtatct atgctttcta tgtgttaaat
      361 atctttagtt tactcaaaac attttttaga agtaaagtga attatgcgtt tcttggtatt
      421 gttttaattt ttatactatc tatttttata gatgaaatgg tggaggctca tgtacttttc
      481 aataagcgcg atgtcatttc aattgttttc tggtattatt tgggaagcat ttcttacttg
      541 tatttaaaaa aggagaatta atatgaagac agctttcatt gcttggactc ctttacattt
      601 gattaatata ttaaatgttt atcaaaattt ttaccgagaa tcaaaaggag atttatttat
      661 ttattctgaa tttgaaaacg ctagaagata tagtgagcgt ataaaagaat tagggctatt
      721 taatgatgtt gtttttgtga atcaccggaa aatcggttct tcctttaaac gtaaaattaa
      781 cttgttaact aaccataatc aatttttctc ggatgattta tccgtttatg atgaaatttt
      841 tatacagggg gaaaattatt tcacaaaaat acttttctcc aatgtttaca aaaaaaatcc
      901 agatgtaaaa ctaaattata tagaagatgg tttgggtact tatttgaaga agagtatatt
      961 ttcaacaagt aaaaacgttc aaagagtttt taaaatatta aataaaaata gcatcttcaa
     1021 aaaaaaa
//
LOCUS       DADVXV010000215         1001 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.227, whole genome shotgun sequence.
ACCESSION   DADVXV010000215 DADVXV010000000
VERSION     DADVXV010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.227"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            370..1001
                     /locus_tag="KB969_002968"
                     /pseudo
     CDS             370..1001
                     /locus_tag="KB969_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          184 g          294 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta c
//
LOCUS       DADVXV010000216          986 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.228, whole genome shotgun sequence.
ACCESSION   DADVXV010000216 DADVXV010000000
VERSION     DADVXV010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.228"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..>986
                     /locus_tag="KB969_002969"
     CDS             <1..>986
                     /locus_tag="KB969_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBB6870864.1"
                     /translation="LEPGDFIMSGAGTIGRISRVPKQIKPGVFNQALIRLRINKEITD
                     SEYFIQFIRADFMQRKLTGANPGSAITNLVPMSEVKKWIVQFPILEEQKKIGNFFKQL
                     DDTIALQQRKLDLLKETKKGFLQKMFPKNGAKVPEIRFPGFTEDWEQRKFKEFSKKTG
                     KKNTKDLDFPAYSVSNKAGLISQTEQFDGSRLDDLEKTNYKFVEPNEFAYNPARVNVG
                     SIAFNNLGMTVIVSSLYVVVKMSEDLDNEFILQFIKSPTFIKEVKRNTEGSVREYLFY
                     ENFANIKFPFTRNKEEQQKIGAFFKQLDDTIALHQRKLDLLKETKKGFLQKM"
BASE COUNT          375 a          159 c          189 g          263 t
ORIGIN      
        1 ttagaaccag gcgattttat catgagtggc gctggaacaa ttgggagaat ttcaagagta
       61 ccaaagcaaa taaaaccggg tgtattcaat caggctttga ttagacttag aataaataaa
      121 gaaatcacag attcagaata ttttattcaa tttattcgtg cagattttat gcaaagaaaa
      181 ctcacaggag ctaatccagg ttcagcaatt acaaatctcg taccaatgtc agaagtgaaa
      241 aaatggatag tacaatttcc aatattagaa gaacaaaaga aaattgggaa cttcttcaaa
      301 caactggacg acactatcgc tcttcaacaa cgtaagctag atttattaaa ggaaacgaaa
      361 aaaggattct tacaaaaaat gttccctaaa aacggagcaa aagtgccaga aattcggttt
      421 cctggattta cggaagattg ggaacagcgt aagttcaaag agtttagtaa gaagactgga
      481 aaaaagaaca cgaaagattt agacttccct gcctattcgg taagtaataa agcaggttta
      541 atttctcaaa cagaacagtt tgatggtagt aggttggatg atttagaaaa aacaaattat
      601 aaattcgttg aaccaaatga attcgcctat aatccagcaa gagtaaacgt aggatcaatt
      661 gcatttaaca atcttggtat gacggtcatt gttagctctc tttatgtagt tgtgaaaatg
      721 agcgaggact tagataatga gttcatactt cagtttatca agtcaccaac atttatcaaa
      781 gaggtcaagc gcaacactga aggaagcgta cgagaatact tattctatga gaatttcgct
      841 aatatcaagt ttccttttac taggaataaa gaggaacaac aaaaaatcgg cgctttcttc
      901 aaacaactcg acgacacgat cgctcttcat caacgtaagt tagatttgct gaaggaaacg
      961 aaaaaaggct tcttacaaaa gatgtt
//
LOCUS       DADVXV010000217          959 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.229, whole genome shotgun sequence.
ACCESSION   DADVXV010000217 DADVXV010000000
VERSION     DADVXV010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.229"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(107..511)
                     /locus_tag="KB969_002970"
                     /pseudo
     CDS             complement(107..511)
                     /locus_tag="KB969_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(570..>959)
                     /locus_tag="KB969_002971"
     CDS             complement(570..>959)
                     /locus_tag="KB969_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870865.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          287 a          170 c          159 g          343 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccattggg agcgtcaata attttgtgta
      541 aataaattgt cctcctgcaa aataattagt tactcagtaa acattgaaac taatgtatcg
      601 gttacctgtt gaaaaccttt atggcttctg tttagaaatt tttgattgta tgtatcaaaa
      661 atgctgacta gaaagcgttc tagtgattct tcattttgaa actgctcttt tctacggctg
      721 tatcttttaa tttgcttatt gaaagactcg attagattgg ttgagtaaat ggttctacga
      781 atgctaggtg gaaaatcata aaaagttaat aagtcttggt tttctatgag tgactgcgtc
      841 actttaggat agtttttctt ccatttctca atcatgccgg ataagaaggt attcgcttct
      901 tcttttgagt tagcttgata aacagcctta aagtcatcac agatttcttt tcggtcttt
//
LOCUS       DADVXV010000218          943 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.230, whole genome shotgun sequence.
ACCESSION   DADVXV010000218 DADVXV010000000
VERSION     DADVXV010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.230"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..>943
                     /locus_tag="KB969_002972"
     rRNA            <1..>943
                     /locus_tag="KB969_002972"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DADVXV010000219          862 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.231, whole genome shotgun sequence.
ACCESSION   DADVXV010000219 DADVXV010000000
VERSION     DADVXV010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.231"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(201..599)
                     /locus_tag="KB969_002973"
     CDS             complement(201..599)
                     /locus_tag="KB969_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBB6870866.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(596..832)
                     /locus_tag="KB969_002974"
     CDS             complement(596..832)
                     /locus_tag="KB969_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBB6870867.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
BASE COUNT          269 a          157 c          120 g          316 t
ORIGIN      
        1 taaaaaatca gcccactagt tctaaaccac tatttcctac tattcactct tttgtattcc
       61 ttttaaatca attatttcaa aattaatcca tattttccat atttttatga aaaaactatt
      121 ttgtatgatt aaacataaaa aaatcagcat attccttaat gacatgctga tctaattgag
      181 aaataaagtt tttaattcgt tcattttatt gcggtttgtc gtaaataact ggttatcttg
      241 gactttagtg aatcgaaatc caatgaacta gtggtaatca ttatgataaa atcaacagct
      301 tcttgacgag aaaaagcaac tggacaatta ttcaattgaa gaaacaacaa catggcaaca
      361 agagcagttc gtttattgcc attatgaaaa ggatgttttt tagctaaatt aattgctaaa
      421 atcgccgctt tttcatagat ttcaggatag agttcttgat tgaatactgc ttgtgaaggc
      481 tgtttgacgg ccatatctaa tgcatttgca tcttttacac cgatcatttc gcctggcgag
      541 tgacgtaaaa taactttcgc gttgattttg ataatttctt tagtcgaaag atacctcata
      601 aatcaaccaa atcttttaac gcgtcttcat attgattcat gatcgaatca actaatgaat
      661 caatatcagg ttcttcttgt gctttgatca ttcgtacaga accatcagat tgaaaaacat
      721 aactgattgc gtcacctgtc tgcacaccca tgaattcttt tacttctggt gggatagttg
      781 ttacatcgct attgccagat tttctaattt tatacttttt catttttttc atatttcgcc
      841 accctctata ccattctcat tc
//
LOCUS       DADVXV010000220          857 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.232, whole genome shotgun sequence.
ACCESSION   DADVXV010000220 DADVXV010000000
VERSION     DADVXV010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.232"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..116
                     /locus_tag="KB969_002975"
     CDS             <1..116
                     /locus_tag="KB969_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBB6870868.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
     gene            244..795
                     /gene="raiA"
                     /locus_tag="KB969_002976"
     CDS             244..795
                     /gene="raiA"
                     /locus_tag="KB969_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBB6870869.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT          306 a          151 c          177 g          223 t
ORIGIN      
        1 aaaaaatatt gattattgac gatgtctata caacaggaca gacgcttttt catgcagcag
       61 attgcttgca gaacgcacag ccgaaaatca tccgaaccat ttctttggca agatgaatca
      121 gatgtggaaa tttgatagcg atttaatttg caaataacct agagttcgat ataatagaat
      181 taagaagagg gaaagagtgg tccttctcct tcttgattgt ggtagacgaa aggggtaatt
      241 tttatgttta gatataatgt acgcggcgaa aatatcgaag taactgaagc gattcgcgac
      301 tacgttgaga aaaaagtagg caaactagaa cgctatttca gtgacgcacc cgatgcaacg
      361 gcgcatgtga acttaaaagt ttatacagaa aaaacagcaa aagtggaagt aacgatccca
      421 ttaccttatc ttgtattacg tgccgaagaa acttctccag atttatacgc aagtatcgat
      481 ttggttgttg acaaattgga acgccaaatc cgcaaattca aaacaaaaat taatcgtaaa
      541 tcccgtgaaa cgggcatgaa tactgcagat gctgctgctt tattcaatga agaggacgaa
      601 aacgaaaatg attctgaatt agatatcgta cgtacgaaac gcctttcatt gaaaccaatg
      661 gatagtgaag aagcagtctt acaaatgaac atgctgggac ataacttctt tatttttgaa
      721 gatgcagaaa caaatggtac aagtatcgtt taccgccgta aagatggaaa atacggactg
      781 attgaaacag actgatcagc cttacttaaa taacaacgaa aacttgcagc agctactgac
      841 agctgccgca agttttt
//
LOCUS       DADVXV010000221          848 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.233, whole genome shotgun sequence.
ACCESSION   DADVXV010000221 DADVXV010000000
VERSION     DADVXV010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.233"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..>848
                     /locus_tag="KB969_002977"
     CDS             <1..>848
                     /locus_tag="KB969_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HBB6870870.1"
                     /translation="EEATQPITADDTEFVSSATKLDDIIENPGDNIPAGYHKVTFTAG
                     EGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSA
                     TKLDDIIENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKD
                     GYTDAKWPEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEG
                     IKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADK
                     YEPTVEG"
BASE COUNT          341 a          140 c          190 g          177 t
ORIGIN      
        1 gaagaagcaa ctcaaccaat tacagcagat gatacagaat ttgtatcaag tgcaacaaaa
       61 ttggatgata tcattgaaaa cccaggggat aacattccgg ctggctatca taaagtaacc
      121 tttactgcag gagaaggaac aagtattgaa agtggaacaa cagtctttgc agtgaaagac
      181 ggcgtaagct taccagaaga taaacttcca gtgttgaaag caaaagatgg ttatacagat
      241 gcgaaatggc cagaagaagc aactcaacca attacagcag atgatacaga atttgtatca
      301 agtgcaacaa aactggatga tatcattgaa aatccaggag aaaacattcc tgcaggctac
      361 cacaaagtaa ccttcaccgc aggagaagga acaagtattg aaagtggaac aacagtcttt
      421 gcagtgaaag acggcgtaag cttaccagaa gataaacttc cagtgttgaa agcaaaagat
      481 ggttatacag atgcgaaatg gccagaggaa gcaactcaac caattacagc agatgataca
      541 gaatttgtat caagtgcaac aaaactggat gataaatctg acgctgacaa atataatcct
      601 gaaggtcaaa aagtgactac agaattgaat aaggaaccag acgcatttga gggaattaag
      661 aacaaagaag atttaccaaa agatactaag tatacttgga aagaaaaagt agatgttagc
      721 gcagctggaa ataaaaaagg gactgttgta gtgacatatc cagatggatc atctgatgaa
      781 gttgaagtag atgttacagt gacagacaat cgttctgacg ccgataaata tgagccaaca
      841 gtagaagg
//
LOCUS       DADVXV010000222          808 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.235, whole genome shotgun sequence.
ACCESSION   DADVXV010000222 DADVXV010000000
VERSION     DADVXV010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.235"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            14..>808
                     /locus_tag="KB969_002978"
     CDS             14..>808
                     /locus_tag="KB969_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870871.1"
                     /translation="MEIFGFYDTAFHINRALSLESIFSSPINFETFRSYGMQVNNFYP
                     WLTLYPLFLLIKFTNLAIGYNLFLYIVTLITLFICHYVMYEITKKHVTSSFFAIIYTT
                     SSFRSVEIFLRGAMGELLAMSILPLILLGFIKLYDSKKESWVMLAISMTLLIYTHVLS
                     VAMTMVMIIIALIIQFYRKKKIEIFLIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLN
                     RPYVDILQKRAIYLGKEFLIGSIDSELLSFGIGLTLLICLIILTFNF"
BASE COUNT          253 a          113 c          118 g          324 t
ORIGIN      
        1 agcatttaaa aacatggaaa tatttggctt ttatgatacg gcatttcaca ttaatcgtgc
       61 gttaagttta gaatctattt ttagctcccc tattaatttt gaaacgttta gatcatatgg
      121 catgcaagta aataattttt acccatggtt aactctatat cctttatttt tattgatcaa
      181 gtttactaat ttagcaatag gctataacct ttttctttat attgttacgc tcattactct
      241 atttatatgt cattatgtaa tgtatgaaat taccaaaaaa catgttacta gctccttttt
      301 cgctattata tatacaacat cttcttttag gagtgtagaa atatttcttc gaggggcaat
      361 gggggaatta ctcgcaatgt caatacttcc tcttatttta ctcgggttta taaagcttta
      421 cgactcaaaa aaagaatctt gggttatgtt ggcgattagc atgactttat taatttacac
      481 tcatgttctt tctgtagcta tgactatggt aatgattata attgctttaa ttattcaatt
      541 ttatcggaaa aagaaaatag aaatcttctt aattattaaa ttaataaaag ctgctatagt
      601 tactttactt ctttcactag cgtttatagg tcctatgatt gagcagacat tgtatcaaga
      661 tctgaataga ccttatgtgg atatattaca aaaaagagca atttatctgg gtaaagagtt
      721 tttgattgga agtatagatt cagaattact atcatttggt attggcttaa ctttgcttat
      781 ttgtttaatt atactaacat ttaacttt
//
LOCUS       DADVXV010000223          807 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.236, whole genome shotgun sequence.
ACCESSION   DADVXV010000223 DADVXV010000000
VERSION     DADVXV010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.236"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            147..779
                     /locus_tag="KB969_002979"
     CDS             147..779
                     /locus_tag="KB969_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBB6870872.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
BASE COUNT          286 a          113 c          131 g          277 t
ORIGIN      
        1 gtgtctctca gggcaattct aagaacgttt caagagatag cgacactatc gttatcgaaa
       61 aaggcgaaaa cctatctcat tttctgctaa tgtaagttgg tttagctttt gttaatatga
      121 ctttatgaaa atggaggtaa ttaaatatga tttttcctaa agttaatgaa gcaagcttga
      181 ataaaggatc cttttttcat atctatgaaa acgaagattt tgaactgtat aatatccttt
      241 cacaaaaaga ggtcatcgaa aaccaaataa tctgccatcc aattatttac aaatctattt
      301 tcaagtatgc attttttgct tccaatgatt ttcaaagaat ggagattacc gactgtatat
      361 tcgaaaactg tgatttttca ggctgtatat tgacaaaaag catgttgcat cgcgtgaaat
      421 ttgtcaattg taaattaaca ggtactaaat tgatggaaag ttatattggg aacacgttat
      481 tcgagaattg taaaatggac tatgtaaatt tatctggttc aaacataaaa gaaagtacct
      541 ttgagcactc tgtcttatca agcgcagatt ttgtagactg ttccctcact aaaataatgt
      601 tttctactaa tgatttagaa aatgctagct tttttgatac tgatttaaaa aatatcgatt
      661 taagtagcaa ctcctttgaa atgattgaag tacgctcgga acatctaaaa aattgtacgc
      721 ttaatcagtt gcaagcactt ggttttgcta gaaaattttt acaaataaaa gtagtataat
      781 caaaatgaat atataagata aattttt
//
LOCUS       DADVXV010000224          757 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.237, whole genome shotgun sequence.
ACCESSION   DADVXV010000224 DADVXV010000000
VERSION     DADVXV010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.237"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(53..126)
                     /locus_tag="KB969_002980"
     tRNA            complement(53..126)
                     /locus_tag="KB969_002980"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(90..92),aa:Ile,seq:cat)
BASE COUNT          272 a          119 c          125 g          241 t
ORIGIN      
        1 ataatactct tcaaaaaatt ctaacacaga acgattcaat tggctacatt aatgtaccct
       61 gtaggactcg aacctacgac cggacggtta tgagccgtct gctctgacca actgagctaa
      121 gggtagtggt tgttgccaca taaagccata aacaatcaac cagtagaatg cgtggcaaca
      181 aacctgttat cgcatatctt ggagtgtgac tatttatgag tgatagtgaa gatatgcgtc
      241 tccatatatg tatggttgag acagataaac atgtatgaaa aacgttgtta aatcaacgtt
      301 tttttatttt ggtcaaggag agaaaagtag agaaatacaa aattttttgc attgattttg
      361 cattcaaaaa aacattcaaa catttagaaa tccccaatac gtattcagga aaatctattt
      421 taaggtttac aaaaagaact tttgttcgta cactcttttt gaggtgaact tttatgctga
      481 tggaaggaaa aacacaatta tggtttaagc atgttccttc aaataagttt tttaattata
      541 aactctagag aaattaattc atcctaacat aaaataattg ttcactcaaa agtttttcta
      601 gaacaattaa aacagcaggc ttcacattcg ctatacattt gtaagaagta ataattcctg
      661 tactaaaagg cataattgct ttaattattt tttgacttct cttcaaacac aagaagtagt
      721 tgtgtaataa ttgcagaaat aaggattcca ataatag
//
LOCUS       DADVXV010000225          728 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.239, whole genome shotgun sequence.
ACCESSION   DADVXV010000225 DADVXV010000000
VERSION     DADVXV010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.239"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..>728)
                     /gene="wzy"
                     /locus_tag="KB969_002981"
     CDS             complement(<1..>728)
                     /gene="wzy"
                     /locus_tag="KB969_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HBB6870873.1"
                     /translation="YLQIILYLFFPALICLLIGSNFSKVITRFVFIIFALYSLLGIMS
                     GDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVITKARDGGGLSKL
                     TLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTYLTSLLGSISTR
                     MLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVYIFIIGIVIGKI
                     LSNSIDNQDIENHPMKMFLAITTA"
BASE COUNT          283 a          126 c           91 g          228 t
ORIGIN      
        1 tttgctgtag ttatagccaa aaacatcttc ataggatgat tttcaatatc ttggttgtct
       61 atactattag aaaggatttt accgatgact ataccaataa taaaaatata gactataccc
      121 ccaatgtatc caccattgac ataggcttct gcaatcattg agaatccagt cccccaagtg
      181 attcctaaat aatcctgaga aaaccaatca gctaataaaa caaactttat tccaaacatt
      241 gatagcattc ttgttgatat agagcctaag agtgaggtca aataagtatt agcaaaggga
      301 tatattccat taccacttat taggaaaaaa gttataatac tcatagtccc ccccatttca
      361 aaaaaagaat caactaaagg agaatcatct gaatcaaata cagatgtaaa atcttttaaa
      421 gtaagtttac ttagtcctcc accatcacgt gctttcgtta ttacgtttag aatatatatt
      481 cctataacag ctaaaataag ccactttatt aattttttat aattaaaggt tcctttatat
      541 tgagtgtatg cccatatgag tataatagag ctatacaacc aacttcctct gtctcctgac
      601 ataattccta ataaagaata taaagcaaaa ataataaaaa caaatctcgt tattactttt
      661 gaaaagttgc taccaattaa taaacatatt aaggctggaa aaaaaagata tagaataatt
      721 tgtaaata
//
LOCUS       DADVXV010000226          721 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.240, whole genome shotgun sequence.
ACCESSION   DADVXV010000226 DADVXV010000000
VERSION     DADVXV010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.240"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(246..446)
                     /locus_tag="KB969_002982"
     CDS             complement(246..446)
                     /locus_tag="KB969_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBB6870874.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          264 a          110 c          122 g          225 t
ORIGIN      
        1 atcacctcga aaagagtata cgaacaaacg ttctttttgt aaaggtggaa tttattatac
       61 taaataaata ggtgaacaag tacttgtgcc aaattatgtg ccaaaaaaaa tcgaatttaa
      121 taaaacacaa acaaaaagaa atcctattat gataacattt cttataataa caaacacaac
      181 agaagacgtg taatagttag tcaggaacgt acaaataacc cctgtatcct ttgcggtaca
      241 gggggttatt ttgtataagt agacattgta gtttctaaac tgctatgtcc taaacgtttc
      301 gatacgctaa gtatatttac tccttgataa agtaaaatag atgcatgcgt atgtcttagt
      361 ccatcaataa acagtcgaag agaaaatagg gaaaaattga ttactaaaga aaaacttact
      421 aggtcgacgg tgtagttgat tttcatactt caatagattc gaattaaacg atttcgattg
      481 gcttatacca gtcctatcca acgaaagata tatcgttctt aactctagcg gtataacttg
      541 aagctttacg taaagccaat gggaatgaac tggagatgac tttttattat ttttagtaat
      601 agctgatggg ttaatactta caactttcct tttcaaagta ccatataaaa aaacggtggg
      661 gttgtttagc gaaataaagg atctaagcca atagcttaga tcctttattc tatgctttat
      721 a
//
LOCUS       DADVXV010000227          670 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.243, whole genome shotgun sequence.
ACCESSION   DADVXV010000227 DADVXV010000000
VERSION     DADVXV010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.243"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..446)
                     /locus_tag="KB969_002983"
     CDS             complement(<1..446)
                     /locus_tag="KB969_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870875.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT          198 a          118 c           90 g          264 t
ORIGIN      
        1 aactttctct tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat
       61 actttataag ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata
      121 tatttttcct gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga
      181 gataacagag ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg
      241 acggttactc gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg
      301 atcgtttttt tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac
      361 tctgataaat ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct
      421 ttgcttaaaa aaaactcata attcattagt catcagctct ttctacgtat attactttcc
      481 atgcattcac caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca
      541 gcgattcttg tttgtataat atacatcgtc ctgtcttttt tttaacattt tggagagcgt
      601 tttatttggc ctttctcgcg atcaaacctg ttattagaat tatatcattt actagtatgc
      661 atttttatta
//
LOCUS       DADVXV010000228          662 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.244, whole genome shotgun sequence.
ACCESSION   DADVXV010000228 DADVXV010000000
VERSION     DADVXV010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.244"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            122..457
                     /locus_tag="KB969_002984"
                     /pseudo
     CDS             122..457
                     /locus_tag="KB969_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            553..>662
                     /locus_tag="KB969_002985"
     CDS             553..>662
                     /locus_tag="KB969_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870876.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELT"
BASE COUNT          234 a          127 c          132 g          169 t
ORIGIN      
        1 tttatataat aaaatgcaat acttttcgag agtgtaaaat attttgtgta aatagaaaaa
       61 aggaagtccc ttctgtagaa tagagttacc acaacacatt cacagaaaag aggacttcca
      121 tatgaacgat tttactacag aaattctaaa gactctagcg aacaaaggcg atttgaatga
      181 attattccgt gtccatttgg aaaaagctgt caatacgctt ctcaaaacgg agttaacggc
      241 tttcctcgat tacgaaaagt acgatcgcat tggttttaac acgggtaatt ctcgtaacgg
      301 ctcctatgac cgtacggtca agaccgagta cggggaactt catctccaga ttccgcgcga
      361 ccgcaacggc gagttcaagc aacagactgt tcctgcttat agacggacga atgatacctt
      421 agaggagacc gtcattcacc tcttccgaaa aggtatggat aggctacaat taactagtgg
      481 ataggctaca attaactaga cagaaaaatt aaggtgtgta gactagaaga aaacatacca
      541 ggaggaattt ttatgtctaa gagaacacga agaacttttt cacaagaatt caagcaacaa
      601 atcgtcaatc tttacttagc tggaaagcca cgtgtagaaa tcattcgaga atatgaacta
      661 ac
//
LOCUS       DADVXV010000229          625 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.246, whole genome shotgun sequence.
ACCESSION   DADVXV010000229 DADVXV010000000
VERSION     DADVXV010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.246"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            1..625
                     /locus_tag="KB969_002986"
                     /pseudo
     CDS             1..625
                     /locus_tag="KB969_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          247 a          105 c          118 g          155 t
ORIGIN      
        1 gtaaagcaat ctaaaacgag tggttcattc aaagaaaaag ataatcttac gcctgaacaa
       61 aaagaattgt tagaactacg taaaagaaac cagcaattag aaatggaaaa tgatatttta
      121 aagcaagcag cgctgatatt cggacgaaga gacaagtaat cgatgcgaat aagcatcttt
      181 accctatatc agcgatgtgc agaatattag gtctatcacg tcagtcctat tattatcaat
      241 caaaaccaaa gaaagacgaa tcagaacttg aagaagtagt cgctgaagaa tttatccgca
      301 gccgaaaggc ctacggctca agaaaaataa aaaaagcctt atcaaaacga ggcattcaga
      361 tcagccgacg aaaaattagt agaatcatga aaaatagagg attaaaatcg agctatactg
      421 ttgcttattt taaagtacat cattctactt gcaatgaagc caaaacgaca aacgtattga
      481 atcgtaaatt cttaagagac aacccattag aagcgatcgt aacagacttg acttatgtac
      541 gagtcgggaa aaaatggaat tatgtctgtt tcattttgga tctgttcaat cgagaaattc
      601 tcggctattc ttgtggagaa cataa
//
LOCUS       DADVXV010000230          582 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.249, whole genome shotgun sequence.
ACCESSION   DADVXV010000230 DADVXV010000000
VERSION     DADVXV010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.249"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..>582
                     /locus_tag="KB969_002987"
     CDS             <1..>582
                     /locus_tag="KB969_002987"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBB6870877.1"
                     /translation="KLLNKELADNIGISEVLLSYVLNRKRNPSKEMQKKIDIFLLSNE
                     KEILKEINRDSEIFSLSKDDKIVMGKRIREVRKNREETLEKFGKNFTIYTGKNVISRW
                     EKGINIPDIEKLMNIAYLGKVTVPYLMYGEDYKNILPKDERVSDFKKINSFSMGLRMR
                     KIRKDYYLEREEFGKLFSPSISKWSIDRYENGR"
BASE COUNT          239 a           54 c          119 g          170 t
ORIGIN      
        1 taagttactt aacaaagagt tagctgataa tataggaatt agtgaagtat tactcagtta
       61 tgtgttaaat agaaagagaa atccgtcaaa agaaatgcaa aaaaaaatcg atatttttct
      121 attaagtaat gaaaaagaaa ttttgaagga gattaatcgt gatagtgaga tatttagttt
      181 atcaaaagac gataaaattg ttatgggaaa aagaatacga gaagtccgaa agaaccggga
      241 agagacgctt gaaaaatttg gtaaaaactt taccatctat acaggcaaaa atgttataag
      301 tagatgggaa aaaggtatta atattccaga tattgaaaaa ctaatgaata ttgcctatct
      361 tggtaaggtc actgttcctt accttatgta cggagaagat tataagaata tacttccaaa
      421 agatgaaaga gttagcgatt ttaaaaagat aaattctttt agtatgggat taaggatgag
      481 gaaaattagg aaagattatt atctagaaag ggaggagttt ggaaagcttt tttctccttc
      541 aatttcaaaa tggtccatag ataggtatga gaatggtaga ga
//
LOCUS       DADVXV010000231          558 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.252, whole genome shotgun sequence.
ACCESSION   DADVXV010000231 DADVXV010000000
VERSION     DADVXV010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.252"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..>558
                     /locus_tag="KB969_002988"
     CDS             <1..>558
                     /locus_tag="KB969_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBB6870878.1"
                     /translation="EIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNFFVSNKKT
                     NGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETGIVGTLSV
                     DVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHDNNYSHTI
                     IEDAYLEEIKEFFTLLEKKMEPQYT"
BASE COUNT          202 a           69 c           99 g          188 t
ORIGIN      
        1 agaaattcaa tatattaagt ctaaagtgac gcataataaa aaaatttctt atcaatacca
       61 tgtaggacag tatttacccg actggcatcc ttgggaagat tatcgcaatt tttttgtttc
      121 aaacaaaaaa actaatgggt gtagagaaat attcgctatt gaattacctt ggattataga
      181 tacatttggg aaagttaaat cgtttactgt aatgacccag aaattatcca atcttgatat
      241 tgattattcg gacagtttca ctcttattat tgagcatgaa actggtatag ttggaacttt
      301 aagtgtagat gttgtttcaa gagtagctaa aagaaattta actataattg gtgaaaagat
      361 tttaatagaa tgggaaggta acccggattc tctattttca tggaatgaag aaacttctag
      421 tatgacagat attcaattgt acgatgaggt tatgcatgat aataattatt cacatactat
      481 tattgaagat gcatatttag aggagattaa agaatttttc acgcttttgg aaaagaaaat
      541 ggaaccccaa tatacttt
//
LOCUS       DADVXV010000232          534 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.253, whole genome shotgun sequence.
ACCESSION   DADVXV010000232 DADVXV010000000
VERSION     DADVXV010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.253"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..>534
                     /locus_tag="KB969_002989"
     CDS             <1..>534
                     /locus_tag="KB969_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HBB6870879.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DADVXV010000233          498 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.255, whole genome shotgun sequence.
ACCESSION   DADVXV010000233 DADVXV010000000
VERSION     DADVXV010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.255"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            112..306
                     /locus_tag="KB969_002990"
     CDS             112..306
                     /locus_tag="KB969_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870880.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          212 a           64 c           82 g          140 t
ORIGIN      
        1 aaaactttca aattgattct ttttatttat cataaagata tagatacata atcattttca
       61 cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca aatgtattat
      121 gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat cagtaacgaa
      181 tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg tgccataaaa
      241 ataaagaacg agctagaaaa agaactgact tgtggtaaag ctgttgtaga tatcatcgaa
      301 aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac aaattgctaa
      361 gattatagaa ttagaagaag aagacgcagt gttgacaatt gaaaaaaaat aaatgtttgt
      421 ataccatatg attatttcaa tatgtatcct ggaattggag atctcgtaga gctatatcaa
      481 gatgaatcaa atatactt
//
LOCUS       DADVXV010000234          487 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.256, whole genome shotgun sequence.
ACCESSION   DADVXV010000234 DADVXV010000000
VERSION     DADVXV010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.256"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..>487)
                     /locus_tag="KB969_002991"
     CDS             complement(<1..>487)
                     /locus_tag="KB969_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBB6870881.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DADVXV010000235          476 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.257, whole genome shotgun sequence.
ACCESSION   DADVXV010000235 DADVXV010000000
VERSION     DADVXV010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.257"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(138..437)
                     /locus_tag="KB969_002992"
     CDS             complement(138..437)
                     /locus_tag="KB969_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBB6870882.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT          150 a           92 c           58 g          176 t
ORIGIN      
        1 ggataaaata caatataaag aaacatctgt ttctttattt agaataaaaa aatacagact
       61 ctgttcaaat aaatgaacct agcctgcatt atgagattga ctatactttt taattcattg
      121 agatgaataa ctcgttttta taaatgccca aaagtaatcg gtgccgaagc cattcctcga
      181 cctaattctt tttcaaattt tcctattgtt gatatctcca tataaaacgg tgatactggt
      241 ttagacaatt ctcccctgat tgctaacgga cgtaaactac gttccaaatt atttatgact
      301 ttaggataat actgaccttt ttctaagcct gtctttgcgt ctatcaaaag tatacgttcc
      361 ttttctttga tctctggatt taaaacgaga tcatataatt ttagtaccat gttttctatt
      421 tcttcacttt tagacatcac gatttcctcc caaaaatata tttcttccca ctacat
//
LOCUS       DADVXV010000236          465 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.258, whole genome shotgun sequence.
ACCESSION   DADVXV010000236 DADVXV010000000
VERSION     DADVXV010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.258"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..>465)
                     /locus_tag="KB969_002993"
     CDS             complement(<1..>465)
                     /locus_tag="KB969_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870883.1"
                     /translation="LHLSGVSNSIHANKDSLTLIAPEDAVAIAENYNHTDYANKESIY
                     HPDMINNDQYLLGNQEINPTTHFMSNKLTIELDNSNNKNTVLTTPIYRYKGQVASING
                     KLVQTKLSKFGTTELTIPPGINKVVITYQYTKLAIASRYLSIVTLILFLLYR"
BASE COUNT          153 a           59 c           80 g          173 t
ORIGIN      
        1 aatcgataaa gtaaaaataa aatcaaagta acgatagata aatatcttga agcaattgct
       61 agttttgtgt actgataagt aataacgact ttatttatac ctggaggaat agttaattca
      121 gttgtgccaa acttagataa ttttgtttgt actagtttgc cattaataga agccacttgc
      181 cctttataac gataaatagg tgtcgtcaag acagtatttt tattattcga attatctaat
      241 tcaattgtaa gtttgttact cataaaatga gttgttggat ttatttcctg gttacctagt
      301 aaatattgat cattattaat catatcagga tgatagattg actctttgtt tgcataatca
      361 gtatgattgt aattttcagc tatagcaaca gcgtcttcag gtgctataag tgttaatgaa
      421 tctttgttag catggataga attgcttact cctgagagat gcaat
//
LOCUS       DADVXV010000237          464 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.259, whole genome shotgun sequence.
ACCESSION   DADVXV010000237 DADVXV010000000
VERSION     DADVXV010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.259"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            <1..>464
                     /locus_tag="KB969_002994"
     CDS             <1..>464
                     /locus_tag="KB969_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870884.1"
                     /translation="LVTKGDLNELFRSHLEKAINTLLRTELTAFLDYEKYDRTGFNSG
                     NSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVT
                     MSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDAT"
BASE COUNT          168 a           85 c           77 g          134 t
ORIGIN      
        1 ctagtcacta aaggcgattt aaatgaatta ttccgttcgc acttagaaaa agcgataaac
       61 acactcctac ggactgaatt aacggctttt ttagattacg aaaaatatga tcgcactggt
      121 tttaattcag gtaattcgag aaacggttct tactttcgat caatcaaaac cgaatatggt
      181 gaattaacat tggaaatacc tagagatcgt aatggtgagt ttaaacaaca aactttacca
      241 gcctacaaaa gaacaaacga tacattggaa accactatta tccatttatt cgaaaaaggt
      301 gttacgatgt ctgaaattgc tgatttgatc gaaaaaatgt acggtcatca ctatactcca
      361 caaaccatgt ccaacatgac taaagttctg actgaagaag taaatgcctt taaatccaga
      421 gccttaaatg ataagtatgt cgctattttt atggacgcta ctta
//
LOCUS       DADVXV010000238          414 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.261, whole genome shotgun sequence.
ACCESSION   DADVXV010000238 DADVXV010000000
VERSION     DADVXV010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.261"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(109..>414)
                     /locus_tag="KB969_002995"
     CDS             complement(109..>414)
                     /locus_tag="KB969_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBB6870885.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          116 a           96 c           82 g          120 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggt
//
LOCUS       DADVXV010000239          410 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.262, whole genome shotgun sequence.
ACCESSION   DADVXV010000239 DADVXV010000000
VERSION     DADVXV010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.262"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(<1..132)
                     /locus_tag="KB969_002996"
     CDS             complement(<1..132)
                     /locus_tag="KB969_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBB6870886.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          141 a           80 c           80 g          109 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat
//
LOCUS       DADVXV010000240          409 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.denovo.263, whole genome shotgun sequence.
ACCESSION   DADVXV010000240 DADVXV010000000
VERSION     DADVXV010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.denovo.263"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            136..>409
                     /locus_tag="KB969_002997"
     CDS             136..>409
                     /locus_tag="KB969_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870887.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTF"
BASE COUNT          145 a           55 c           73 g          136 t
ORIGIN      
        1 agctatatta gctttttccg aaaataaaca acctgtaact gcaaaaaaag aaacagtatt
       61 ctctgaaggc aaaataaaaa ctcgatatat attagaggta gagactaagt ttaaaaatag
      121 atcggagtaa tggttatgct ttttaatgag acgcaattat ggtttaaatt tgatccttcg
      181 aatagatttg tcaaagattt ttataaggtg tgggattcag aagttttctt tttagcaatc
      241 gaagatagct tattaattaa tctctactat tctaataaga actactttaa aatccctgct
      301 gcgaaaacta gaatgaagaa agacgtatat tttttgtttg atatcgtgac tgatgtgcta
      361 gacgctcgaa gcgatcatcg gcgttatgac tatataaagt atactttcg
//
LOCUS       DADVXV010000241        26384 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.guided.034, whole genome shotgun sequence.
ACCESSION   DADVXV010000241 DADVXV010000000
VERSION     DADVXV010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.guided.034"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            1..245
                     /locus_tag="KB969_002998"
                     /pseudo
     CDS             1..245
                     /locus_tag="KB969_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
     gene            502..690
                     /locus_tag="KB969_002999"
                     /pseudo
     CDS             502..690
                     /locus_tag="KB969_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            736..1701
                     /locus_tag="KB969_003000"
     CDS             736..1701
                     /locus_tag="KB969_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870888.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            1723..1935
                     /locus_tag="KB969_003001"
     CDS             1723..1935
                     /locus_tag="KB969_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBB6870889.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            2010..2486
                     /locus_tag="KB969_003002"
     CDS             2010..2486
                     /locus_tag="KB969_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBB6870890.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            2483..4291
                     /locus_tag="KB969_003003"
     CDS             2483..4291
                     /locus_tag="KB969_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBB6870891.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            4368..4583
                     /locus_tag="KB969_003004"
     CDS             4368..4583
                     /locus_tag="KB969_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBB6870892.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            4675..5538
                     /locus_tag="KB969_003005"
     CDS             4675..5538
                     /locus_tag="KB969_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870893.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            5575..6111
                     /locus_tag="KB969_003006"
     CDS             5575..6111
                     /locus_tag="KB969_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HBB6870894.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            6125..6547
                     /locus_tag="KB969_003007"
     CDS             6125..6547
                     /locus_tag="KB969_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6870895.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            6477..8876
                     /locus_tag="KB969_003008"
     CDS             6477..8876
                     /locus_tag="KB969_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBB6870896.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            8908..10899
                     /locus_tag="KB969_003009"
     CDS             8908..10899
                     /locus_tag="KB969_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBB6870897.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            10922..11173
                     /locus_tag="KB969_003010"
     CDS             10922..11173
                     /locus_tag="KB969_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBB6870898.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            11163..12392
                     /locus_tag="KB969_003011"
     CDS             11163..12392
                     /locus_tag="KB969_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBB6870899.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            12389..14470
                     /locus_tag="KB969_003012"
     CDS             12389..14470
                     /locus_tag="KB969_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBB6870900.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            14619..18539
                     /locus_tag="KB969_003013"
     CDS             14619..18539
                     /locus_tag="KB969_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBB6870901.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKTD
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLIERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            18540..19484
                     /locus_tag="KB969_003014"
     CDS             18540..19484
                     /locus_tag="KB969_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870902.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            19488..19691
                     /locus_tag="KB969_003015"
     CDS             19488..19691
                     /locus_tag="KB969_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBB6870903.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(19991..20227)
                     /locus_tag="KB969_003016"
     CDS             complement(19991..20227)
                     /locus_tag="KB969_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBB6870904.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(20410..20796)
                     /locus_tag="KB969_003017"
     CDS             complement(20410..20796)
                     /locus_tag="KB969_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HBB6870905.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(20778..22106)
                     /locus_tag="KB969_003018"
     CDS             complement(20778..22106)
                     /locus_tag="KB969_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBB6870906.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(22067..22396)
                     /gene="mobC"
                     /locus_tag="KB969_003019"
     CDS             complement(22067..22396)
                     /gene="mobC"
                     /locus_tag="KB969_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBB6870907.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(22654..23024)
                     /locus_tag="KB969_003020"
                     /pseudo
     CDS             complement(22654..23024)
                     /locus_tag="KB969_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            23169..23354
                     /locus_tag="KB969_003021"
     CDS             23169..23354
                     /locus_tag="KB969_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBB6870908.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            23512..23679
                     /locus_tag="KB969_003022"
     CDS             23512..23679
                     /locus_tag="KB969_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870909.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            24297..24956
                     /gene="vanR"
                     /locus_tag="KB969_003023"
     CDS             24297..24956
                     /gene="vanR"
                     /locus_tag="KB969_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HBB6870910.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            24959..26320
                     /gene="vanS"
                     /locus_tag="KB969_003024"
     CDS             24959..26320
                     /gene="vanS"
                     /locus_tag="KB969_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBB6870911.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPNFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLT
                     STL"
BASE COUNT         6543 a         6981 c         7210 g         5650 t
ORIGIN      
        1 tttataaaat gcatggtgat atagatgatg tcagttcgac agtaataaca agagatgatt
       61 atgaaaaata tgatgattcg tacgcgttat ttaaagaaac tttaaaagga gatttgttaa
      121 caaaaacttt tctcttttta ggatttagtt ttacagaccc taatttagaa agaattttat
      181 cagatataag atgggttttg agagaaaacc aaagacctca ttattgtata atgagaaaaa
      241 tattatagaa aaaattttag gttatcgctg aaagccccgg aaatacgggc atttcgcagg
      301 atatgagaac tcaatttact accaatttac tactttcgga ttgagccgca tatatgctga
      361 accatactgc taatacccgc caccccaaat acggcacatc ataaattgaa tacgacaccg
      421 taaacgcggc gttcctcttt cccgtcatgg gagaacagga cgccgctttt ttatgcccaa
      481 atagagaaag gaggcgacgc catgctattt acttccggcc ctgaccgggc gtttgaacgg
      541 ctgatgcagg aaaagcccgg tttcgatcac tacgacggcg gcggggcgga cgcgccggag
      601 gattgcggca cctgccgatt ttaccgcccg gattggaaat atcaattctg ccagtttgca
      661 gagtgtccct atcagccggg caagctgacc gactatgcag cggtcaaatt cacagtgaaa
      721 ggagcgaaca acgctatggc agttttccgt gtggaaaaga acaaaggcta tacggtgatg
      781 tcaaatcacc acctgcggaa taagaacctg accttaaagg ccaagggcct gctgtcgcag
      841 atgttgtcct tgccggagga ttgggactat accctaaaag gactgtccta tatcaaccgg
      901 gaaagcatcg acgcgatcag gacagcggta tgggagcttg aaaaagctgg atatatccgg
      961 cgtgagcagg gccgtgacgc aaaaggcaaa atggccgata tggtctatac catctacgaa
     1021 cagccggtat tggaaaaccc ggtattggaa aatccaacat cggataaccc ggtgttggaa
     1081 aatccgacat cggataatcc ggcgtcggaa aatccaacgc aattaaataa agaagtacaa
     1141 agaactgact tatcaaaaaa agaaaaaata attacagatg gacaaagtac ccattccatt
     1201 cctatcccat ccccgacccc tgcccctatg gagggcgagg cagcggctac gccgccggaa
     1261 cggaaaagga caggaaagga tgaggctgta cggatttatc gggaaatcat tttggagaac
     1321 atcgagtatg cctatctcat tcaggacagg agcattgacc gtgaacagct tgacgaaatc
     1381 gtagacctga tgctggaaac cgtctgcacc gcccgaaaga caatccgtgt cgccggggac
     1441 gactaccctg ccgagctggt gaaatccaag tacatgaagc tgaccggcga acatatccgc
     1501 tttgtccttg actgtctgcg ggagaacaca acgaaagtcc gcaatatcaa acaatacctg
     1561 cgggctatgc tgttcaacgc ccccagcacc atttccaact actacacggc ccttgtcgcg
     1621 cacgacatgg cacagcccga ttggggaaag cctaaatccg gcctgccgga ctattcctgc
     1681 ggcgagggcg aaagcctgta acgagaaaag gaggacgacc ctatgaagca gggcgcattg
     1741 atttttgacg agcgaacaga ccgttacgac atccgctttg atctggccga ctattacggc
     1801 ggcctgcatt gcggggagtg tttcgacgtg atgatcggcg gcaaatggag gcccacccgc
     1861 attgaaatgg ccgaaaactg gtatcttgtc ggcatccggg ccgacgacct ttccggcctg
     1921 cgggtgcgga tttgacctat atctacctgc ggcgtctggt ggttccgcct tagacgccgc
     1981 ttttgacttt ctgacaagga gggatgcgat tgcaggaaga agttactcaa aagaccattg
     2041 ccctgtccat gaaaacgggc aagctcacgg ctcaagtgct gcaagcggcg ctgaaaaagt
     2101 acctgcaaca ccgggccaag ggcaaaaaca cgctgcacca cggccagcag agcctaaagc
     2161 agcttaaaaa gcatggggct gatctctcca acattgagat caccgaggcc aacattggag
     2221 cgttcaagcc atgcgccaag aaatacggcg tggattttac cttacgaaaa gataagacca
     2281 cccagccgcc ccactacgtt gtgattttca aggccaagga tgcagataac cttgatctgg
     2341 cgtttcggga gtttaccgcc aagacgcttt ccaaggagca gcggccctct atccgcaagg
     2401 ttttgtccgc tgtgaagcaa aaggcggcgg cccagaccaa gcagcgggcc aaggagaaaa
     2461 tcaaggaaag ggggctggaa ctgtgaagcc tgacgtaaag aaattgctga tcctgaacct
     2521 cccgtatctg atttttgtgt acctgtttgc gaaatgcggg gaggcgtacc ggctggccgc
     2581 tggtgctgac ctgtcgggga agctcctgca ttttgcggat ggttttgcgg cggcttttgc
     2641 caacccgctg ccaagcctgc acctgtttga cctgtgtatc ggtatcgccg gtgccgtgat
     2701 cgtgcggctg gtggtgtact gcaagagcaa gaacgtgaag aaataccgca aaggcatgga
     2761 gtatggcagc gcccgctggg ggacggccaa agacatagcg ccttacatcg accccaagtt
     2821 tgaaaataat atcctgctca cccaaacgga acggcttacc atgaccggca ggcccaaaga
     2881 ccccaagaca gcgcggaata aaaacgtgct ggtgatcggt ggcagcggtt cagggaaaac
     2941 gagatttttc gtgaaaccca acctgatgca atgctttccg accacggact atccgacttc
     3001 gtttgtggtg acagatccga aaggcacttt ggttctggaa accggcagga tgttccagca
     3061 ggcgggctac cgcattaaaa tcctgaatac cattaacttt tccaagtcca tgaagtacaa
     3121 cccctttgtc tacatccatt cggaaaagga cgtgctaaag ctggtaaata ccctgatttc
     3181 caacaccaag ggcgaggggg aaaagtcagc ggaggatttt tgggtgaagt cggaacggtt
     3241 gttttattcg gccctgatcg gctatatctg gtacgaggcc ccagcggagg aaatgaactt
     3301 ctcaacgctg ctggaaatga taaacgccag tgaagcccgc gaggacgacc cggagtttca
     3361 aagccccgtc gatctcatgt ttgagcgttt ggagcagaaa gaccccgacc attttgcggt
     3421 gcgccagtac aagaaattcc tgctgtccgc aggcaagacc cgttcttcca tcctgatttc
     3481 atgcggtgcc agacttgcgc cctttgacat ccgggaggta cgcgagctga tggaggacga
     3541 cgaaatggag ctggacacca tcggggacga aaagacggtg ctgtatctca ttatgagcga
     3601 tacggacacg acctttaatt tcattctggc tatgctccaa agccagctaa tcaacctgct
     3661 ttgtgaccgg gctgatgatg tgtacggcgg gcggctgcct gtccatgtac gcctgatttt
     3721 ggatgaattt gccaacattg gccaaatacc caatttcgat aaactcattg ccaccattcg
     3781 aagccgtgaa atatcggcct ctattatttt gcagagccag tcgcagctaa aagcgattta
     3841 caaggacgcc gccgagatca tttcggataa ctgcgatagt gtgcttttcc ttagtgggcg
     3901 cggcaaaaat gccaaggaga tttccgatgc gctggggaaa gaaacgattg acagtttcaa
     3961 caccagcgag aaccggggaa gccaaacgtc ccacggattg aactatcaaa aattaggaaa
     4021 ggagttgatg tcccaagacg aaattgccgt gatggacggc ggcaagtgta tcttgcagct
     4081 acggggtgtg cgcccgtttt tatcggagaa attcgatatt accaagcatc cccggtacaa
     4141 ataccttgcc gacgccgaca agaagaatac ctttgacgtg gacagatttt tgactatcac
     4201 gcgccggaaa cggcagcaag tggtaacgca ggatgaagta ttcgacctgt atgaaatcga
     4261 cctgtcggac gaggacgccg ccgctgaata aacagcggct tttttcattc caacaacaaa
     4321 atcaaaaaat cattatgagc cggaaaccgg cagaaagagg taaatttatg gcatttttta
     4381 attccgcagt tactactttg cagactatcg tgatcggact gggcggcgct ctgtgcgtat
     4441 ggggcggcat caatctgttg gagggatacg ggcaggacaa tccgggggca aaatcgcagg
     4501 gtgtcaagca gcttgtcgct ggcggcggcg tggccctgat cggtgtcact ctggttcccc
     4561 tgctgtccgg gctgctgggc tgatcctggc ctttgtccct gtccaaaccc ttaactaatc
     4621 gcctccgcgt cctcccggcc agaccgggag ggcgcgggaa aggaggtgct acccgtgatt
     4681 agtgaaatca ttgaagaatg gataaaaggc atcctcatgg acggtatcac gggcaacctg
     4741 tccgggctgt tcgatacggt aaatgccaaa gtcggagaaa tcgccgccga cgtgggacga
     4801 accccgcagg catggaacag cggtattttc aatatgctgc acagcctgtc ggaaaccgtg
     4861 atcgtcccca tagccggggc catactcgcc cttgtcatgt gctatgagct tatccagatg
     4921 ataacggaaa agaacaatat gcacgacttt gacagctcca tgttcttccg ctggatattc
     4981 aaatccgcgt ttgcaatcct gatcgtaacg aacacatgga acatcgtcat gggcgtattc
     5041 gacgccaccc aaagcgtcgt caatcaaagc gccggtgtga ttatcgggca gacatccatt
     5101 gattttaaca ccctgatacc agaccttgaa agccaattgg aggctatgag cgtgggcgct
     5161 cttttggggc tgtggttcca aacccttgtt gtgggcctca ccatgaatat cctttccatc
     5221 tgcattttcc ttgtgaccta tggccgcatg gtggaaatct atgttgtcac gtcgctgggg
     5281 cctatccccc ttgccacaat gggcaacgcg gaatggcgcg gcatgggcca agggtatctg
     5341 aaatccctgc tggcgctggg cttccaagcc tttttaatca tggttgtggt gggtatctac
     5401 gcggtgctga tacagaatat cggttccgct tccgacatat ccggcgcaat ctggggctgt
     5461 atgggctata cggtgctgct gtgcttctgc ctgttcaaga ccggcagtat atcaaaggcc
     5521 gtattcgggg cgcattgatc ccaaaatcca agcatacaca ggaggaactt gtttatttca
     5581 acgtacaaca tcatttacgc tgacccgccg tggcggtatg actgcaaaaa cgtacagggc
     5641 gcagcggaaa atcactattc caccatgagc attgacgagc tgtgcgccct gccggtggaa
     5701 cggctggcgt ccaaagactg cctgctgttt ttgtgggcca cattccccat gctgccggaa
     5761 gctctgcggt taatcaaagc gtggggcttt tcattcaaga ccgtggcttt tgtatggctg
     5821 aaacagaacc gtaaaagcct tacatggttt tacgggctgg gccgctggac aaggggaaac
     5881 gcggaaatct gcctgctggc aacacacggc aagccgaagc gtcgttctgc ctctgtccat
     5941 cagtttatta tcagcccgat tgaacaacac agcaaaaagc cggatgtgac ccgtgaaaaa
     6001 atcgtagagc tggcgggcga tttgccccgc gtggagctgt ttgccagaca gaaaaccccc
     6061 ggctgggacg tgtgggggaa cgaggtggaa tgtgacctta tcctgacgtg aaaggaggtg
     6121 ccaaatggct tatgtaaccg tccccaagga cttaacccat gtgaaaagca aggttgtgtt
     6181 tgggcttacc aaacggcaac tgatctgttt ttccggggcg ctggtgatcg gcgtcccctt
     6241 atattttctc acccgtgact atcttaccaa cagcgcggcg gccctgctca tggtatttgc
     6301 catgctgccg ggctttttgc ttgccatgta cgagcgtcac ggccagcccc ttgaagtggt
     6361 gattatgcag atcatccagt gctgcttcat ccagccaaag gagcgtccct atcagaccga
     6421 caacacctac accgcccttg tgcggcaata ccagatggaa caggaggtaa aggccattgt
     6481 ccaaaaagga aatcccaaga gaaaccgaaa aaacaaagct gacccgcgcc cagcgaaaag
     6541 aaattgacgc ggtaatccgt aaatataagg gcgacggcag gccccacacg gcgcagcaga
     6601 gcatccccta cgaggtcatg tacccggacg gcgtgtgccg ggtatcgccc ggcgtctttt
     6661 ccaagtgcat tgagtttgcg gacatcagct atcagcttgc ccagccggac acgcagacgg
     6721 ctatctttga aaaactgtgc gacctgtata actatgtgga cgcctccatt catatccagt
     6781 tttctttcct caatcggaaa gttgacccgg tgcagtacgc caagagcttt gagatcgcgc
     6841 cgcaggggga cgacttcgac gacatccggg ccgagtacac cggcattctg caaaagcagc
     6901 ttgcaaacgg caacaacggc atggtaaaga ccaaatacct gacattcacc atcgaggccg
     6961 aaagcgtgaa agcggcgcga gccagattga agcgcatcgg ctttgacctg ttaggctatt
     7021 tcaagagcat gggggccgta gcccatgtga tggacggctg ggaacggctg aacctgctgc
     7081 atggcgtgta ccacccggac ggcgagatat tcaattttga ctggaagtgg ctggccccgt
     7141 ccggcctctc caccaaggat tttattgccc cgtcctccct gtgcttcggc aatgcaaaga
     7201 cattcggcat gggcggcaaa tacggcgcgg taagtttcct gcaaatcctg tccccggagc
     7261 tgtcggacga tatgctggcc gacttcctca atacggaaag cggtgtttta gtcaatctcc
     7321 atgtgcaggc cattgaacag accaaggcga tcaagaccat caagcgcaaa attaccgacc
     7381 ttgacgctat gaagattgcg gagcagaaaa aggccgtccg cagcggttac gatatggaca
     7441 ttcttcccag cgaccttgcc acctacggcg aggacgccaa gaagctgctg acaaagttgc
     7501 agacccgcaa tgaacggctg ttccagttga cgttccttgt cctcaacgtg gccgacacca
     7561 agcaaaagct gaataacgac gtgttccaag ccgcaggcgt ggcccaaaag cataactgtc
     7621 cccttgtccg gctggactac cagcaggaac agggccttgc aagcagcctg ccgctgggcg
     7681 tcaatcagat caagatacag cgcagcctta cgacttccag cgtggccgtg ttcgtcccct
     7741 ttgtgacgca ggagcttttt cagggcggcg cggccatgta ttacggcatc aacgccaagt
     7801 cccgcaacat gattatgctg gacaggaagc aggcccgttg ccccaatgcc ttgaagctcg
     7861 gcacccccgg cagcggcaaa tccatgagct gtaaatccga gatcgtcagt gtgttcttaa
     7921 cgacgcctga cgatattttt atttcagacc cggaggccga atattacccc cttgtcaaac
     7981 ggctccacgg acaggtaatc cggctgtcgc ctaccagcaa ggactttgtg aacccgctgg
     8041 acatcaacct gaattattcg gaggacgata acccgctggc cctgaaatcc gactttgtgc
     8101 tgtcgttctg tgagcttgtc atgggcggca agaacgggct ggaagccatt gaaaagaccg
     8161 tgatagaccg ggctgtgcgc gtgatctacc ggccctatct ggcagacccc cgcccggaga
     8221 atatgccgat cctgtccgac ctccacaaag cgttgttaga tcagcatgtc ccggaggctg
     8281 accgggtggc gcaggccctt gacctgtatg tgtccggctc cctgaacgta tttaaccacc
     8341 gtaccaacgt ggacatcggc aaccggcttg tgtcctttga cattaaggag ctgggcaagc
     8401 agctcaaaaa gctggggatg ctcattgtcc aagaccagat atgggggcgc gtcacggcca
     8461 accgaagcca aggaaaggcc acatggtatt ttgccgacga gttccatttg cttttgaaag
     8521 aggaacagac ggcggcctat tctgcggaga tttggaagcg gtttaggaaa tggggcggca
     8581 ttccaacagg tgccacccag aacgtcaaag acctgctttc ctccccggaa attgaaaata
     8641 tccttgaaaa cagcgacttc attacgctgc tcaatcaggc gtccggggat agaaaaatcc
     8701 ttgcggaacg cttgaatttg tccaccgaac agcagaagta catcgacaat tccgaacccg
     8761 gcgagggcct tttgatcttt gaaaacgtgg tgctgccctt taccaacccc atcccgcaca
     8821 acacccagct ttacaagatt atgacgaccc gcttaaacga ggtggcggga gtatgacccg
     8881 gcgacgccac aaaggaggtg aaccaccatg aaagagctga aagccaaggc gaaagtgacg
     8941 caggccatga cccgcgacgg gctgacgctg gaaaatcagg ccaccggcga ggtggagaac
     9001 atttccagcc gggaggccga acaggatttg tccgcgccgg ggccgggcgg caccgccgat
     9061 aagctgctgg aacgggccga cgccatccat gacggccata aggccaagaa agccgcgaag
     9121 caggccgggg ctgtggccgc cgagggggac gctgccctgc accggccatc cgcccggctc
     9181 caactgtcgg aggaagaacg ggccgacccg gatttacagc cctatatccg aaaatcggac
     9241 aaacgggccg ataagctgga taaggcccgc gccgccatcc ccaagaagcg cgtcccggtc
     9301 aaggaaaccg tctttgacga ggcaagcggc aaagcaaaga ccgtcctgca ctttgacaaa
     9361 caggacaagg ggcctccctc cctgaaaccc aatccggcag gccgtcctgt ttccgaggtt
     9421 tttctattcg gccacgggaa aatccatgaa gtcgagcatg aaaacgtggg tgtggagggc
     9481 ggccataagg gggaggaact tgccgagcgg caggccggaa aagccatccg cagcaccatc
     9541 cggcaccaca ggctgaaacc ctactgggac gcggaaaagg ccgagcgcag gctattgtct
     9601 gccaacgcgg agtatttcta ccagaaatct ttgcgggata acccggagat cgcacaggcg
     9661 gccagcaacc ccatttcccg gttctggcag aaacagcaga tcaagcgcca gtacgccaag
     9721 gccgcccgga cagcgggcca gaccgcaggc gcggcggcac agggcgcggc caagacagcc
     9781 ggggcctcca cgaaagcggc caaggccgca gccaaagaaa gtgaacgggc ggcctccttt
     9841 gtggcccgcc actggaaagg ggcgctggcc gtccttgtgt tggggctttt gatgctgctt
     9901 atcatcggcg gcttacagtc ctgcaccgcc atgttcggca gcgccggaag cggcatcacg
     9961 gcgtcctctt acttttccga ggatagcgat atgttggccg ccgaggacgc ctacgcggag
    10021 ctggaagccg agctgcaaga ctatctggac aactacgagg ccacccatga ctatgacgaa
    10081 taccattttg accttgacga gatcagccat gacccctatg tgctgatttc cattctgtcg
    10141 gcgctccatg acgggatatt taccatcggg gaggtacagg gtgatttgtc catgctcttt
    10201 gacaagcaat atatcctgac agaaaacgtc gtggtagaaa cccgttaccg caccgaaacc
    10261 gatacatgga cggacgcgga gggcaacacc catacagaca cctaccaagt gccgtatgac
    10321 tattacatct gctacgtcac gctggaaaac ttcgacctgt cccatgtgcc agtctatatc
    10381 atggacgagg aaacgctaag tttctattcc ctgtatatgt ccacgctagg aaaccggcct
    10441 gatctgtttt ccggcagcca gtaccccaac gcctccaccc tgacgccgcc gacctactac
    10501 gacgtacccc cggaggcttt ggaggatgcc acctttgccg ccatgctcaa agaggcggaa
    10561 aaatatatcg gttatcccta tgtgtggggc ggcagctctc ccagcaccag ctttgattgc
    10621 agcggcttca tttcgtgggt aatcaatcat agtggatgga acgtgggacg gctgggggcg
    10681 cagggcctat ataacatctg cacccctgtt tccagttcgc aggccaagcc cggcgacctt
    10741 gtatttttca agggaaccta cgacaccccc ggcgtgtccc acgtcggcct gtatgtgggc
    10801 aacaatgtga tgctgcattg cgggaacccg atttcctaca cgaaccttac ttcaaactac
    10861 tggcaatccc atttttacag ttacgggcgt ttaccttaac gccagaaagg agctttcaat
    10921 tatggcaacc aaacttgacc gcatcgaaaa ggacatccag aaaaccaagt ctaagatcgc
    10981 ggagtttcag aaacagcttc gggagctgga aacgcagaaa accgaacagg agaatttgca
    11041 gatcatccag cttgtgcgcg gcatgaacat gaagccggag gaatttgccg cgttcttacg
    11101 cagcggcgca atgcaggccg cccctgccgc aaccccttac catgaacagg aggacaatgc
    11161 ccatgaagaa taagaccaga cggatttccc gtattctccc cgcacttctg gccgtgatgc
    11221 tctgcgtcac ggcctttccc gttaccgccc ttgcaggcgg caatgacccg gcaccggccc
    11281 cgctgccgga ggctacaacc gaacccgcta cgggcggttt ggagcctgaa acagacgaaa
    11341 ccggcaccgc cacggacggg acagaaaccg aggccgaaaa agataccggc cctctgaccg
    11401 gcaaggacat caccgacctg ttttccgcgc tgttcggttc caaggtgagc attgccgcca
    11461 cggacgacgg catccagatc accaccggca ccgacaaaaa agaacctgaa cagaccggca
    11521 ccgtcaccac caacggcggc aggctgaatg tccgcaccgg cgcggggctt gacaagaccg
    11581 cgttcaccca gcttcccaat gggacgacgg ttgaggtagt cggcacagac ggcgactgga
    11641 ttaaaattct cttgccggag cgcatcggct atgtccattc cgactatatg accgtcagcg
    11701 aaaaggaagt agcggctacc ggcgagggcg gtttttccct ctccattgac ccggaggaaa
    11761 ttgcttctct gctggaactg ttcaatggcg gcggggccag cgccgccctg tccccggacg
    11821 ggaacctgtc actgattgac gacatcggca gcgccgcgaa aaatggcaag cagtttatca
    11881 ccgtggaaac caaaaacggc aatgtgtttt atctgattat tgaccgggac gacgagggaa
    11941 aagaaactgt ccatttctta aatcaggtgg atgaagccga tctgctgacg ctgatggagg
    12001 acggggaaac cgtcaccccc gctgctgtct gctcctgtac cacgaaatgc aaggccgggg
    12061 ctgtgaacac gaattgcccg gtatgtaaaa ccaacctgac cgagtgcagc ggcccggagc
    12121 cgcaggaacc ccagccggag gaacccgaag ccccggagga agaacccaag ggcggcgcgg
    12181 gcggcctgat cgtgttcctg ctggtggcgc tggcgggcgg cggtgcggcc ctttactatt
    12241 tcaagttcaa aaagcccaag gctgaaacca ccggcagcga cgatttgggc gagtatgatt
    12301 ttggggagga cgaggatttg gaggacgagg aacccgaaac cgagtttgac ccggaagctg
    12361 attttgtgag tgaacaggag gacgaggaat gacatataaa cttgtaatcg cggaaaaacc
    12421 cagcgtggcc cgcagcattg cgggcgtgat cggggccacg gagaaacacg acggctattt
    12481 ggaggggaac ggctatctgg tgagctggtg catcggacat ctggtgtcct ttgccgacgc
    12541 cggacgctat gacgagcgtt tcaaaaaatg gcgctatgag gatttgccca ttctcccgga
    12601 aacatggcag tacatcgtcc ccgacgacaa gaaacagcag tttgacgttc tctgttcgct
    12661 gatgcagcgc cccgacgtga ccggccttgt gtgcgccacc gacgccgggc gcgaggggga
    12721 attgattttc cgtttcgtct accagatggc gggatgccaa aagccctttg agcgcctttg
    12781 gatttcctct atggaggaca gtgctattaa ggacggcttt gcccacctga aaccgggcgg
    12841 cgactatgat ccgctgtatc aatcggccct gtgccgggcc aaggccgact ggctgatcgg
    12901 cattaacgcc acccggcttt tttccgtcct gtaccacaag aacctgactg tgggccgcgt
    12961 ccagacgccg accttaaaaa tgctggtgga cagggacgcc aagattaccg atttcaagaa
    13021 agagaaatat cacatcgtcc atatcacggc gggcggcgcg gacgcggtaa gcagccgctt
    13081 ttccgacgct gccgaggcaa acaccgtcaa ggcggcttgt gcaaaagcgc aggccgtttg
    13141 cgtttccgtg acgcgggaga aaaagacgga acagccgccc aagctctatg accttaccac
    13201 cttgcagcgg gaggctaacc ggcttttcgg ctataccgcc aagcagaccc ttgactatgc
    13261 ccaggcactg tatctaaaga agctgctgac ctatccgaga acggatagtc aatatcttac
    13321 cgacgatatg ctgcccgccg tggaaagcct tgtgtccggc ctgtgggagc tggtgccgtt
    13381 tgccaagggc ctgaaccttt ccccgcagtt tgaccgcatc ctgaacagca aaaaggtgtc
    13441 cgaccaccac gccattatcc ccaccgctga atttgtgaag cagggctttg gcactctggc
    13501 cgagagtgaa aaaaagctgc tgtccctgat ctgctgcaag ctcttatgtg ccgtggccgg
    13561 gccgcatatc tatgaggccg tcaccgccac atttacctgt gccgggcagg agtttaccgc
    13621 caagggcaag accgtccttt cccccggctg gaaagagatt gaacgccggt tccgttcttc
    13681 cttaaagacc gacgccgacg aggacgccga ggcggtgcgg gagctgccgg agctttgcga
    13741 gggccagacc tttgcagacg tggccgcctc tgtcaccgag catttcacca cgccgcccaa
    13801 gccctacacc gaagatacgc ttttgtccgc tatggaacgg gccggggccg aggatatgcc
    13861 ggaggatgcc gagcgcaagg gattaggcac accggccacc cgcgccgcca ttctggaaaa
    13921 gctggtgcag atgggctttg tccagagaaa aggcaagcag ctcattccca ccaaggacgg
    13981 catcaatctg gctgtggtgc tgccggaggc gcttacttct ccccagctta ctgccgaatg
    14041 ggaaaaccgg ctgaccgaga tcgccaaggg gcaggccgat cctgacgaat ttatggacgg
    14101 catcgagacg caggcgcggg agctggtgca gacctattcc tgtatcagtg aggaaaagca
    14161 gaaattgttt caggccgagc gtgttcctat cgggacgtgt ccccgctgtg gtgaggctgt
    14221 ctatgagggc aagaaaaact actactgcgg aaaccgggcc tgccagttcg tcatgtggaa
    14281 gaatgaccga ttttttgagg aacgcaagaa agcgttcacc ccgaagatcg ccgctgcgct
    14341 gctcaaaacc ggcaaagtca aggtaaaggg cctctattcc gtaaagaccg gcaaaaccta
    14401 cgacgggacg gtgcttttgg ctgataccgg gggcaagtac gtcaactacc gcattgaaca
    14461 caggagctaa aggacagtaa cacagcaagc atagggagtg tggctacact cccggtaaaa
    14521 tcccccggcc gcgtccctgc cgggccgggg atttttgctt gttggggaag tccccaaccc
    14581 cctatttttt gaaacagaac agagaaagga gtgaccgcgt gaacgaagta ttttctatcc
    14641 aagtccataa ccggcagttt ttggaacagg gcaaacaagg cgtctggctg gatttgccca
    14701 ccacaaccga aacgctgcaa gccgccctgc gggatgttgg cattactgcc gacaatccgc
    14761 aggatttttt tatcaacggg tattcctgcc cggaggacag acaccttgcc attccctatg
    14821 acatggtgct ggccgccgac gtggacgagc tgaatttcct tgccgcccgg ctgggccagc
    14881 ttgacgccgc cgagatcgca gagctgaacg ccgccctgca aaatccccgt ggcggctttg
    14941 agaatatcgg ccagatcatc gactacaccg aaaatgtgga ttactatgtg catcttcccg
    15001 acgttagggg ggatggacag ttgggcgact actacctgaa ccgttccggc atggtggata
    15061 tgccggagga atggaaagcc gggattgata cggcgcagtt tggacgccac attgcccagc
    15121 aggaacaagg cgtttttacc cagtacggct atctggtgag aagcggcgac gaatggcagc
    15181 gcgtccatga gggccagccg gtgccggagg aataccgggt gatgcactac ccccagccgg
    15241 aagctgaccg ggaggaaccg caggcccagc agccggaggc atccgaaagc cccgacaaag
    15301 cgccgccccc ggttatcccg atcatgctgg acggcatgaa cagcaaagaa cgcatgaaag
    15361 tgattactga ccgtctggaa accggcgtac aggagctttt tgaaagtagc cgctatatgg
    15421 cttacttatc cgctatgtcc aagatgcacg attacagtct gaacaatacg ctgctgatcg
    15481 ccatgcaggg cggttcgatt gtggcgggct ataacaggtg gcaggatgaa tttgaccgcc
    15541 atgtgaagcg gggcgagaaa ggcattaaga tactggcccc ggccccgttc aaggttaagc
    15601 agcagatgga gaaaaccgac ccggccaccc agcagcccgt gatcggcgcg gacggcaagc
    15661 ccgtgaccga agaacaggaa gtgacggttc cggcctttaa ggtggtgaca gtctttgaca
    15721 tcagccagac cgagggcaag gattttccca tgccctatat cagtgaactt accggcgacg
    15781 tgcagcagta tcaggatttc tttgccgcgc tggaacggac atcaccctat cccataagca
    15841 ttgagccgat ttcagacggg gccaagggcc gctgcttcta cgcaaaacag cgcattgcca
    15901 tcaacgaggg catgagcgaa ttgcagaccc taaagaccgc catccatgag attgcccatg
    15961 ccaagctcca cgccattgac cgggaggccc ccgccgagga acaggcggcc cggccagacc
    16021 gcagcacccg cgaggtacag gccgaaagcg tggcctatac cgtctgccag tattacgggc
    16081 tggacacgtc ggactattct tttggctatg tggccgattg gagcagcggc agggagttat
    16141 ccgagctgaa agcctccctt gaaaccatcc gggccacggc cagcgaattg ataaccgaga
    16201 tcgacggcca ttttgcccag cttcagcagg agcgcgaggc ccggcaggaa caggaggccg
    16261 tcacggttga cgttaccccg gaggcagcgg ccccggcgca ggccgaggaa gaacaggccc
    16321 cggcccttga tccggcagcc gagccgcttg tgactgtgct atggagcgaa agcccccagc
    16381 taaaggacgg ccagcaaatg ccgttgcatg aggccgacgc gctgtttgcc cgtctggatg
    16441 cagcatatcc ggcagaggca ggctatgaca aaaccgcgtt ccgcattgac tgtatctttc
    16501 agggcgagcc ggacagctac gaggggcggc aggattttgg agatagggac ggttccctga
    16561 tcgaacatat ccagagctac caccaatttt acgcgcagga cgaaaactgg aaaaagcatg
    16621 taatcgctac aaccggcata gagggctggg agcaggacaa ggcccatcgg gatatgctgt
    16681 taggcgagtt tgtcccctat atgaagctgc attgcagcct tgcccaaatg gaacagacgg
    16741 cgcagggccg cttacagtcc ggggaaaccc tgacgccgga ggaaacggcc tatttggggg
    16801 cgcttctctc ttatgtgcag gagtgccgcc ccatgctcaa tcagggccag tatcagttgc
    16861 cggagccgcc gaaactggct gacttcgacc agagcttgca ggactacaaa gcacaggtac
    16921 aggccgagat cgcgcaggag gccgccgcag ccggtatgac cgtggaggaa tacgcggcgg
    16981 ctggctatga agcaccccaa caggacacct tttccatcta ccagcttcga ggcggggagg
    17041 aaacccgcga ctatcggttt gagccatacg agcgtttaca ggccgcaggg ctggccgtgg
    17101 acagtgccaa ctatgacctt gtttatacgg caccgctgga taaaagcacg tctttggagg
    17161 atatttaccg cacattcaac atcgaccacc cggcagattt taggggacac agcctttccg
    17221 tttccgacgt ggtggtgctg caccagaatg gacaggacac cgcccactat gtagacagct
    17281 tcggctatat ggaagtgccg gagtttttgc gggaaaatcc cctgcgtacc gccgaactgt
    17341 ctacggagca gaacgaaaac atgattgacg gcattatcaa caatacgccg cccgaaccgc
    17401 agccggagga acccgaacag ctatcttttg aggatgtggc agttgcttcc ggccagacac
    17461 aggaggaacc cccggaggct gcgcccccgc aaacggctgt ccgctattat cccatcaatg
    17521 agggagccgc ccgccgcgcc aaggaagcca tgagcttttc tgactaccgg cccggcagcg
    17581 ccacggcgga ataccggcac tatgtcgatc aggccgtgga aattgcggag cgccagaaaa
    17641 agcgtgtgga gccagagtat cacgaaaaga tagacagcct ccttgacacc tacgcccgca
    17701 agctggccga gaacatgaat aagggctatg agattaccgc ccgcgtcccc tctgtcctga
    17761 ttgccgggcc gtccaatttc ccggtacggg cgaaagaaaa gcagaacgcc gccagtgacc
    17821 gcaacatgga ggaatttcag tacattcagg gcttgcttga caaaatccgc agcaccggca
    17881 tgggtggtat cagcgccgac gatccgcagg ccgtttccaa gctggaaaag aaactggaaa
    17941 agctggaagc gtcgcaggag ttgatgaagg ccgtcaatgc ctactaccgc aagcatggga
    18001 cgctggacgg atgcccccat ctgatcgaaa gaggcattga aaacctgaaa gcggatatgg
    18061 cgtcgggctg gcactatgag aaaaaaccgt tccagtcctg gcagctctcc aacaataacg
    18121 ccgagatacg ccggttaaag ggccgcattg aggaattgac ccgccaaaag gaggcggcct
    18181 atgtgggatg ggagtttgac ggcggcactg tggagatcaa ccgggtggcc aaccgcctgc
    18241 aaatcttctt tgaggggaag ccggatgctg ctgtacgcga cgagctgaaa agcaacggtt
    18301 tccgctggtc gcccaaggcc ggggcatggc agcggcagtt aaacgacacc acaatccgcg
    18361 tcgctgaccg tatcaagtgc atccagcccc tttccggcga aaagcccagc gccttacagc
    18421 ttgcggcccg cagggagaaa gaaaagccct ctatccgggc gcagctcaac gcggccaaga
    18481 ccgaacaggc caagcagcca ccggcgcggg aaaaatcaaa gggattggag gtagagtaaa
    18541 tgcagaagtt tgaaaatgtg gacgttctgg ccgcgctgga acagatcatg cggcagaaca
    18601 ccgcgtttta tcaaagtgac tttggcattg acaaagacat tatcaggcgg gatgccgcca
    18661 gcgatcaggc cgcagacaag accctgctct ggatgtcccg gccctccggg acgtactgtt
    18721 tccgggaacg tgatgttttc ctgaaagaca cccgacagta caacacatgg aaattttacg
    18781 gggagcagac ccgtgacaag atactggcct acgcggtgga gctgaccggc acacagggcg
    18841 gcactatccg gggcaatctc tatgagctgg actatccgca gcatttccgg cacgtcattg
    18901 aaaccgccca gccggtgagt gtgaaccggc tcttttatga gcatggcacc cgtgacatcc
    18961 cggagagcca gcgttttgac ggaagccctg accgggtatt gggaaacttt ttgtactatg
    19021 aggcccagcc ccatgacccg gctgtgctgc aggaggcgct acggacggag cagcacagcc
    19081 gggggcgggc cgtccccggc gatttcaaag tccacgtcac cgctttgcat gacagccgga
    19141 ttgaaaccga ggcccggcgt attgtggaca gcctgaaaga tctgtccgcg cctaacagcc
    19201 ccaataaaac gcatttcatg gtggagatct ccccgcactt tgcggcgatt gcttccacca
    19261 aggataatga ccggctcttt gccatgctgc cctataaatc cctgtgtttt accgggatga
    19321 aaggcaggca tggcgtgtat gccgtgatta accgggacga gcgccgggat gtgagtattc
    19381 gcaggccccg gccctctatc cgcaagcagc tatccgacag caaacaggcc gccagcccaa
    19441 aaaaggcggc ggccagaacc aaaaagaatg aattggaggt ataaggaatg atgcacttta
    19501 ccgtggagga agaaaacctg atctgtatgt accacaatgc agaccggcgc agaacgataa
    19561 acaggctcac cgccgtcatg ccggttatgg atggggatat gcgggcgcag gcccagcaga
    19621 ccctttccaa gctggaacgc atgacggatg ccgactatga cggccagaag ttccacttca
    19681 cagacgaata acgaacagca gacgccgggc gcggcggcca tgtggtcgct tgcgtccggc
    19741 gtcttttctt tttgcctatt cctacgcatt tagaacccgg tattgtcggg gataggatga
    19801 agtattcgct tgcccctgca aacatgcggg agaagccttg cagcgggcgg ttttcaatcc
    19861 cttaaatgcg taggttgcag ctataattag acccctgaaa cagatatagc cgcgcagcgg
    19921 gtgtatctgt ttcaggggtg tgcaggtgat agccgcaaag cggcgtaaga gggtgcagcc
    19981 ctcttgccgt ctatctctgt tccagcggga agctcggcaa tgcttccagc agtttcaggg
    20041 aaatgcgctg ccgtatatct tcgtcaatga ctttcttctt tttgccgttt gcctgtctga
    20101 tctccaccgt ggaaagctcg ttgatgtagt cagcataatg ggccaacact ttttccgtgg
    20161 cccacctctc accggcaacg gcggctttga tcgtttcata gtccagcagc ttttcttgtc
    20221 cgtccatcct gatacccccg tcagactgat tttttctatg ataccatatt cggaagcatg
    20281 gaaccagaga aaacggcgct tttctgctgg taaattctac gcatttagaa cagcacttcg
    20341 gcggggatag gataaaacac ccacataccc cgctgaccat gccggaaaag ccttgaaata
    20401 taagggcttt tacagctcta agtgcgtagg tttccagtat cttttccgct ggcgctcggc
    20461 ctctttgcgg cggcgcatcc gtttggagca ggccgcgcag tatttggccc ggttagactt
    20521 cggcgtgaac gtggccccgc actcacagca gcgtttcact tcgtcccggt ctttggtgat
    20581 ctcggcatac agggccgcat ccagcgggag gacagcggcc ttaaaccagc ggcacagaag
    20641 cgaataggaa atgctctgta cgcaaataca ttcttcgccg tcgtccagca acaggcagtt
    20701 gccgtcacaa tagttgcagc actcatgcgt cagcttccgg gccttgcgat attgagggta
    20761 attcattcgt ggaatactca tagctcttgc gtccattcct ttcccggcgt catacgcaaa
    20821 atgccgtcca cattctgctt gatgatgccg tattcctgca tctgcttttt cgcttcgccg
    20881 tacttctcat acagccgttc cttttcctcg gccaatcgct tgtactcggc tttcagggcg
    20941 tacagatcgg ggagcttttt cacaccctgt ccctttaggg cctttgccgc agcttcatac
    21001 aaaatcaacg tgctttcatg ctcacgccgg aattttgcct tatccgctgc attgcggtat
    21061 tccatagcca cgggccagag ctgcttgtag gtagaaatat tctttatcag caccgccata
    21121 tccgcaagcc ggtgttccat agctttgagg gtagcggcgg cctcgtcgct ggcggcggtg
    21181 atctcggcca ctttgctttc caaatccggg taggtgtcta tcccatgttc agtcaggaaa
    21241 ttcaaagtct ttgcggcctg cttcaaattg tggagcttcg cccacctctc atagcctgcc
    21301 gactgctggg ccttaatgtt gttttccaga tcaatccgca aagaaatccc cttgcgctct
    21361 ttgggcgctc tggtgataac gcggcctttg atacgctctt tgatggcttc ctcggtgtag
    21421 gcttccccca atgtcttgca gcgggtaaag cgttcctgtc cgggagcgcg gaaagaaata
    21481 aactttcccg gcttgatctc atagccctgc gcctgcatga gccgcaggaa atcatcaaaa
    21541 tcttttgcct gcgggatagc ggcgtcaatg gctgctttga gcttcgcttt ccagctcgtc
    21601 cctttccgct gggcgtccca ctcggcatag ctcttgccct tactctggcc gggcttcacc
    21661 acggacaatc cgttttcctt gcacagcctg tcgctggtgc gccggatata ggcatagctc
    21721 tgtttgttgg aaatgtactt gcgctgattt accatatcca cggcacagaa aataatgtga
    21781 ttgtggacgt ggcccttatc aatatgggta gtcagcacat agggatattt cccttgcagc
    21841 acttcctcgg caagctgctt cccgatctca tgggcctgtt ccggcgtggc ttcgccgggg
    21901 gcaaaggatt gtatcaggtg gtggcccaga ttattgccct tttggtatgc ctgcgccagc
    21961 agcatttcaa attcaatgtc cgctgtttca taagagcagg caaaggaggc caccagcagc
    22021 ttgccgtcag ttttgtccgg gttctcgatg tagtcaaggg cttttttcag cgttgacttg
    22081 ataggatgta tctttgtaac tgccatatct gcgccagcgc cccctttata tcctcgatgt
    22141 cctgtgcgta caccggcccc ataccgttca gcctctttgc aatctgattg acgttgacgc
    22201 cgatcttctg tatctcggcg gtctgcgccc ggatgtcgct ggtgtccatg ttgacgatat
    22261 agccgtcaat gagcatcttc cgggcgtagg ctgaaaagtt cttcgtatgc agcagcgcca
    22321 ttttctgttc aatcatagcc cgttcctccg gcgtcacagg gacgcgcagc acgatttttc
    22381 gctttctgtt tgccatgctt caccgtcctt tccattcagg ggtttgggga tttccccaac
    22441 aagcaaaacg gacgcggccc ggcagggacg gggcaggccg tttttccggg agtggctaca
    22501 ctccctatgc ttgctacgtt actgtttctc cactaacaag acgtttccaa agccccaaac
    22561 tacccgcaaa atagccctct ggaaagaaaa aagtgcaaaa aaatagaagc tacgctgtgc
    22621 agctcccgct aaaagtaaaa cagaggatgc cagttacaca tcctccgttt cattcttctt
    22681 cggcttttca attagtatgg cgctgtcaat cgcgccctcg atgatcggca ggtattcttc
    22741 ggggcagagt ttcagcttgt ggctgaccct ttgccgcagt tcgctttcct cccgcatgat
    22801 ctccgggtta aagtagcgtt ccacaggaag cccgcaggct ttaataagct gtatgacaac
    22861 cggcagactg ggaatggccc gtcgttttcg atgttggcaa gatagcgcca gtcaatattt
    22921 attttctctg ccattgcttt gcgcgaaacg cgctttgctt gccgggccgc tttcacatcc
    22981 gcgccgaaag tttcaaagcc gggacaatct tcaatattcg ccatatcgca cctcccactt
    23041 acattgtata tttcatactc tgcccgtgga atgttggtat atgcaccttt cttaaagttt
    23101 atatttcaca ttttgtttct tttattcttc gagcaaaaga attataatgt accctgtgga
    23161 ggtgtactat ggactacatg acgttgaaag aggcaggcga gaaatggggt gtgcccccac
    23221 gatggataaa ctactattgt gctgcgggac gcatccccgg cgctgtaaag atggcgacga
    23281 tctggctcat tcccaaaact gcggaaaagc cgattgacag gcgtacaaag aaaggaaagg
    23341 cggttactga atagtataat gaaaccggcg cattttggat atggttttga agagagagaa
    23401 agcatggtat tttgtcacgg aaaaactata agatgataga tggcaggctg ctccagaccg
    23461 ataaaaagta ttctcatctg aaacagaaag aaaagattta cacatggatg tatgaagaag
    23521 cgaaacttta tcatgacaga aatggaaaat gcccgaaaca aagacgagga agctgctgct
    23581 gtatcagccg tatatggtag aattgaaaag gccggcatct ggattcttta tggtgaagtc
    23641 tccagacatt ggataactgc tggtctaatg cgcctttgag tatggggtga ttgattttaa
    23701 taccggggag gtacggcttt ttgaggaaaa tattctggga tttacatttg gcgattatta
    23761 catttcctgt aactgcaagg acacggatga tgaagatatg aggaatatag acttgctgat
    23821 tttctactgt cttgaacggt attaggactg aatctgctgc gcggagtgcg gcaagagcga
    23881 ccggagggag tacacacagg ccctgcctgt gtgaaaagcc ataccgcaag gtgcattcgc
    23941 aaaaaagagg ccgcgcattt tgctgaggct tggggtgtcc ccaacaagca aaacgagaac
    24001 gccgcaggcg ggcaagtggt ggatcagaat atccgtaaag gatattctga tccattgctt
    24061 gccagtatta tcgggatgtt ttgacaaccg ctgtaatcga aacatcccaa acattaagaa
    24121 ggtgttaatt attattatct tgatttaatt cgtttaaacc aataatatag atacatacac
    24181 catgaaaaga agcgagtatc ccaatgacgg atgattaaaa tccgaaaaga aatcgctttg
    24241 aaactacagg gaaactacag actgttatgt tatcttctta aaatggaggg atttttatgt
    24301 cgatacgaat tctacttgtc gaggatgatg atcatatctg taatacagta agggcgtttc
    24361 tggctgaggc aggatatcag gtggatgcct gcacagatgg aaatgaggca tacaccaagt
    24421 tttacgaaaa cacttatcaa ctggttattc ttgatattat gctgcccggt atgaacgggc
    24481 atgaactttt gcgtgaattt cgtgcgaaaa atgatactcc cattctgatg atgacagccc
    24541 tgtcggatga cgaaaaccaa atccgggcgt ttgatgcaga ggcagacgac tatgtaacaa
    24601 agccattcaa gatgcagatt ttactaaagc gggtggaagc cctgctgcgg cgcagcggtg
    24661 cgctggcaaa ggaaatccgt gtcggcaggc tgacacttct gccggaggat ttcacggtac
    24721 tttgtgacgg tacagagctg cccctgacac gaaaagaatt tgaaatcctt ttgctgctgg
    24781 tgcagaacaa aggcagaacc ttaacgcatg aaatcatttt gtcacgtata tggggatatg
    24841 actttgaggg tgatggcagc acagtccaca ctcatatcaa aaatttgcgg gccaagctgc
    24901 cggaaaatat catcaaaacc attcgcggtg taggataccg attggaggaa tcataataat
    24961 ggaaagaaaa gggattttca ttaaggtttt ttcctatacg atcattgtcc tgctactgct
    25021 tgtcggtgta acagcaacac tgtttgcaca gcaatttgtg tcttatttca gagtgatgga
    25081 attacagcaa acagtaaaat cctatcagcc attggtggaa ctgattcaga atagcgatag
    25141 gcttgatatt caagaggtgg cagggctgtt tcactacaat aaccaatcct ttgagtttta
    25201 tattgaagat aaagagggaa gcgtactcta tgccacacca aatgccaata catcaaatag
    25261 ttttagaccc aactttcttt atgtggtaca tagagatgat aatatttcga ttgttgctca
    25321 aagcaaggca ggtgtgggat tgctttatca agggctgaca attcggggaa ttgttatgat
    25381 tgcgataatg gttgtattca gccttttatg cgcgtatatc tttgcgcggc aaatgacaac
    25441 gccgatcaaa gccttagcgg acagtgcgaa taaaatggca aacctgaaag atgtaccgcc
    25501 gccgctggag cgaaaggatg agcttggcgc actggctcat gatatgcatt ccatgtatgt
    25561 caggctgaaa gaaaccatcg caaggctgga ggatgaaatc gcaagggaac atgagttgga
    25621 ggaaacacag cgatatttct ttgcggcagc ttctcatgag ctaaaaacgc ccatcgcggc
    25681 tacaagcgtt ctgttggagg gaatgcttga aaatatcggt gactacaaag atcattctaa
    25741 gtatctgcgc gaatgcatca aaatgatgga taggcagggc aaaatcattt ccgaaatact
    25801 ggagcttgtc agcctgaatg atgggagaat cgtacccata gctgaaccgt tggacatagg
    25861 gcgcacggtt gccgagttgc tgcccgattt tcaaaccttg gcagaggcaa acaaccagcg
    25921 gttcgtcaca gatattccag ccgggcaaat tgtcctgtcc gatccgaggc tgctccaaaa
    25981 ggcactatcc aatgtcatat tgaatgcagt tcagaacacg ccgcagggag gcgaggtacg
    26041 gatatggagt gagcctggtg ctgaaaaatg ccgccttttt gttttgaaca tgggcgttca
    26101 cattgatgat actgcgcttc caaggctgtt caccccattc tatcgcattg atcaggcgcg
    26161 aagcagaaaa agtgggcgaa gcagaaaaag tgggcgaagc ggtttaggac ttgccatcgt
    26221 acaaaaaacg ctggatgcca tgagcctcca gtatgcgctg gaaaacacct cggatggcgt
    26281 tttgttctgg ctggatttac cgctcacatc aacattgtaa atatttaaaa cttaaatgat
    26341 tttgggctct ttgtcaaata ggactgatag agtgagataa gaac
//
LOCUS       DADVXV010000242         9318 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.guided.097, whole genome shotgun sequence.
ACCESSION   DADVXV010000242 DADVXV010000000
VERSION     DADVXV010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.guided.097"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            complement(134..577)
                     /locus_tag="KB969_003025"
     CDS             complement(134..577)
                     /locus_tag="KB969_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBB6870912.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="KB969_003026"
     CDS             complement(795..2135)
                     /locus_tag="KB969_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBB6870913.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="KB969_003027"
     CDS             2404..3300
                     /locus_tag="KB969_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBB6870914.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="KB969_003028"
     CDS             complement(3450..4391)
                     /locus_tag="KB969_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBB6870915.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="KB969_003029"
     CDS             4517..5638
                     /locus_tag="KB969_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBB6870916.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="KB969_003030"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="KB969_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBB6870917.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="KB969_003031"
     CDS             7426..7992
                     /locus_tag="KB969_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBB6870918.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="KB969_003032"
     CDS             8203..9264
                     /locus_tag="KB969_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBB6870919.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
BASE COUNT         3128 a         1712 c         1858 g         2620 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaa
//
LOCUS       DADVXV010000243         8786 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.guided.100, whole genome shotgun sequence.
ACCESSION   DADVXV010000243 DADVXV010000000
VERSION     DADVXV010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.guided.100"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            167..622
                     /locus_tag="KB969_003033"
     CDS             167..622
                     /locus_tag="KB969_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870920.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            984..1259
                     /locus_tag="KB969_003034"
     CDS             984..1259
                     /locus_tag="KB969_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870921.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            1272..3350
                     /locus_tag="KB969_003035"
     CDS             1272..3350
                     /locus_tag="KB969_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBB6870922.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            3510..5396
                     /locus_tag="KB969_003036"
     CDS             3510..5396
                     /locus_tag="KB969_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBB6870923.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            5408..6355
                     /locus_tag="KB969_003037"
     CDS             5408..6355
                     /locus_tag="KB969_003037"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBB6870924.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            6375..6902
                     /locus_tag="KB969_003038"
     CDS             6375..6902
                     /locus_tag="KB969_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBB6870925.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6965..7618)
                     /locus_tag="KB969_003039"
     CDS             complement(6965..7618)
                     /locus_tag="KB969_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBB6870926.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7750..8592
                     /locus_tag="KB969_003040"
     CDS             7750..8592
                     /locus_tag="KB969_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBB6870927.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
BASE COUNT         3014 a         1473 c         1850 g         2449 t
ORIGIN      
        1 aaaattgatt taaaaaacac tagactgtat ctgctcagct ttgttggcta cttaaagtgg
       61 gcagatacgt cattagaaga aaaaacataa gatgtgacca cttacataaa tttgtgctaa
      121 actgaggtag tacaagaata aattacatca taaaggagtc tttttaatga gtaaagaaat
      181 gacagcgcta aaattttatt ttagaaatgg agaaacctgg acgatcaacc gccgtcatat
      241 cggcgatctt tggatcaaac aaatcacaac aagttttgga cgaatcaatg gcagtgaatt
      301 tgttgaaatc catccgtgtg ctggatttaa aatcgaaatc ttccatgaag gggacgcagt
      361 tgcgacacat gatatcaacc taggcggact ggaaatgggc atgtttaatc gcgcattgaa
      421 atacgaagat atcgagcgaa tggaaatcct ttaccgaaat ggcacacctg atcttgtgta
      481 cttcccatat ctagataaag gaacagaagg attagacaat caatatcaat caacaaaaat
      541 cagcgaaaaa acaggtaact tgtatatcgt gatcaatcca gatcaacgtg tagaagatgt
      601 atacggggaa tttttcgaat aaatcgattt ttacgcaaaa atgaggctgt gaaagagatg
      661 tgtcttatta ctactgatag gctgtctctt ccacaccgtt tattcagaat aagggactgt
      721 gacaagattt ttgtcgcagc cccatttttt tgttgtgata aaagaacaag aaaggcagga
      781 atgggaaagt aaacatcctt ttgtcagaaa cttttatctt tcttaagttt tacttgatat
      841 ctgatactat ttggaataga atgaggcgtt gaaaaattta tggaaatttc taactagcaa
      901 taaacgatga aacaatgaaa tatttttcat ccaaaaagaa ctttgctata atgatggaag
      961 tttgtgtata ggagatctgg aaaatgagag agagttttga acaacaaaaa aaactgttgc
     1021 atgatcgcta tggcgccctt tcgatggatg accgccgtca aatactttgt aagttgcgta
     1081 aaagaaatat attgatgtat cgtcagttgg aacgtctgaa acatgatctg cttcgtttgg
     1141 agtcaaaacg tgtacagtgt gaattagagg ggaaccaaac acaggttgaa gtagtcgaaa
     1201 ccaaaatttt aaagaaaaaa gaacaatttt taaaaatgct tacacaaaat aaaaaataaa
     1261 ggggatggac gatggaattt gctgagttag ttattgtatt tgcagtaacg atcaccttat
     1321 cgaacatagc tagccgcatt ttgccaatga ttccagctcc actgatccaa attttccttg
     1381 gagtggtatt aggtctgaca gagtggggac aatcaatcga ttttgaacct gaattgttct
     1441 tagttatgat tattgcacca ttgttattta gagaaggaga aaaagcagat atttcttcga
     1501 ttctcaaaaa tttcgggaca attttgttct tggcatttgg aggagtcatt ttgacccttg
     1561 tcggggtagg tgcgacgtta tcattcctgt tgccaagtgt cccacttgct gcctgctttg
     1621 cttttggagc agcgttaggt ccgacagatg cggtagcagt cagttctctt tctggacgag
     1681 tgaatatccc taaaaaggcg atgcatattt tggaaggaga aggtcttttg aatgatgcat
     1741 ctggtgttac tgccttccag tttgctcttg gtgcgctgat caccggatct ttttcagcag
     1801 taaacgcggg gatgagtcta gtagtttcta gtattggggg agctttgatc ggctttttgc
     1861 ttgtctggtt caaacaaaaa ataattcatt tgatcgaaaa agcatcagca caagatgtca
     1921 cagggtatct gctgatcgaa cttttgcttc cttttctagc ctatgtattg gcagaggcat
     1981 ttgatgtatc tggaatcatt gctgcagtgg cagcaggtat tctccaagct tctggtttta
     2041 ggaaaatctc tgtgtttgat gcagaattgt cgagcttgtc ccacagtaca tggacaacta
     2101 ttgcttttac actgaatgca ttagtattta tatttttagg aatcgaattg acgcaagtgt
     2161 tctcgccagt atggggagac ggtttatatc caaacggtct tttattagcg attatcgtat
     2221 taatctctgt catgcttttt gtgatcagat tcatttctat cagtcttttt tatgtattca
     2281 aagatggcag taaaaagttc aaaaaacagt tgaacgagat cttgatctta acatttggcg
     2341 gtgtaaaggg aacagtcagt ttggctacga tttttatttt gccattttca atcaataata
     2401 tgatgtttta ccagcggtct ttgcttttgt ttctgacggc gggtgtcatc ttagtgactt
     2461 tggtcatagg gatcattgtc ttgcctatgc tgacggaaac agaggaagcg aaaagcacgg
     2521 atttgaatgc tttgatgatt ttagaagagg tcgttgaagt tttgcgaaaa gaaataaagg
     2581 aaattgatcg taatacaaaa gaatttttag ccactgaagc agtgatagaa aattatcaag
     2641 aacggatacg tgatctgtac ttggaagatt taaccgatga tgaaaagcaa gaagtacaag
     2701 aaatacaagc actgattttg tcgatcgaac gggatggatt ggatgaaagt tatcgttcgg
     2761 gcaagctttc ttctaatggt tatcgttttt actcccgttt tctttctcga ttcgaacatt
     2821 ctatcacaag ccagattttg tcttttatcg gcttttggtt cattgttgtc cgtaggttaa
     2881 tgcgaatcgt tctccatccg aaaatgtttt ggcaaagaag atatgctgat cgtcagacat
     2941 ttattagtga tgaagatatc caagaaatca gagagacata tcaaaaaaat actcagttga
     3001 ttattgaaag tttagataac ttgactgata tttatgatga aacgatggtt caatttttta
     3061 tccagcaacg caaacttgaa ggaataaaaa tgaactcggg gaatttgatt tcttcgtgga
     3121 tgatccagca agatagtctg tttacgaaaa aaatgctaag aggttattat cttgaaagaa
     3181 aaatcattga tgaatacgaa gttgctgaaa aaatcacgac gttttctgcg aacagctatc
     3241 gcaggaatat caatttgtta gaatcttata cgatgaacaa accatctgat aacttttctt
     3301 tccgatttgc gtttcgagca aagtcaaaaa aaacgagtcc aataaaataa aaaggtaaaa
     3361 attttcaagt tttataaaaa acaaaacata tcagaacagg atcgaatcgg tcctgttctt
     3421 tttttgagaa cacaaaaaga acaaatacca aaaaaatttt cctgaagttc actattttta
     3481 tgatacaata tccaagataa ggagggaaca tgttgaaaga attaaaagta actgacctca
     3541 aaaaaactta tggtgaaaaa gatttgtttg accagatttc ttttttggtc cacgaaaaag
     3601 accgtatcgg gttgattggg acgaacggga cgggtaaaac aagtctctta aatattattg
     3661 ccggtatcga tagcagcgac ggtgatcggc aaacagtgtt ttatccaact gattaccgta
     3721 ttggttatct ttctcaagca gctgaatttt ccgatgaatt aactgttctc caagcagtct
     3781 ttcaaggaaa cagccccttg atccaaactg ttcgagcata tgaggaagca ttgatcgaac
     3841 taggggaaaa cggagaagac cctgatgtgc aaaaacgtta tgctaaagca gaagaacaaa
     3901 tgaataaaga agatgcttgg actacagata ccaacgcaaa gattattttg caaaaattag
     3961 gaatcagtga attagataaa aaaatcagta ctttatcagg tggtcagaaa aaacgagtta
     4021 gtctggcgca agtgttgatt gatgaacccg atttactatt actagacgaa ccaacaaacc
     4081 atttagatta tgaagcgatc gagtggttgg aaaactattt gaaacaatac cgtggcgcac
     4141 tattgatggt tacccacgat cgttattttc tagatagagt agcaaaccga atcttcgaac
     4201 tttcatttgg aaaattatac gagtataaag gaaattatga agcttacgtc ttagaaaaag
     4261 cagaacgtga tcgtgtagaa gtagaacaag aagaaaagcg caagcggctt tataaacagg
     4321 aattagcttg gatgagggct ggcgtacagg cacgtggcac caagcagcaa gcacggatca
     4381 accgtttcga agatctaaag gagaacttgt accaagtaaa ccaagaagat gatttagagc
     4441 tgaacctagc gacacaacgt ttagggaaaa aagtactgga aatcaaagat ggcagttacc
     4501 gtataaatga ccaaacactg ctagaacatt tagatttatt gattcaatct cgggaaagac
     4561 taggtattac tggtaaaaat ggtgcgggaa aatcgacatt gcttaatatt ctagctggca
     4621 gaattcccct ggatagcggt acaatgtcta tcggtgaaac ggttcatctt gcgtattata
     4681 cacaagaaaa tgaagaaatg gcaccagata aacggatgat tgcttactta caagaagctg
     4741 ctgaagaagc aaaaacagca gatggcagtc aaatcggagt agcagaatta cttgaacgat
     4801 ttttatttcc aagatttatg catgggacac tgataggcaa actttcaggc ggagaaaaac
     4861 gccggttatt tttgttgaaa ctgctgattc agcaacctaa tgttttatta ttggatgaac
     4921 cgaccaatga tttggacata gcaacattga cgattttgga agattatttt agaagttttc
     4981 caggtgctgt gatcactgtt tcccatgacc gttatttctt ggacaaggta gcagataagt
     5041 tattagtatt ccaaggaaac ggaaaacaag aactttatta cggaaacatg tccagttatt
     5101 tactgaagca aaaagagacc cagcagcctg ctgaaaaagc gaaaccaaaa atacagagca
     5161 aggaacctgc tgaaaagaag aaattatctt acatggaaca aaaagaatgg gaaacgattg
     5221 aagatgagat tgcagaactt gaagaaaaaa tctcattgct ccaagaagag atgaatcatc
     5281 aaggagataa tttcactcga ttacaagaat tgcaaaacga cgtatctgaa acagaagcac
     5341 aacttgaaga aaaaatggca cggtgggaat acttgagtga atgggtagaa gattaggagg
     5401 aaaaaggatg gaacaagcgt atcttgactt aggaagaaaa ttgttggaag aagggcatcg
     5461 taaagaagac agaacaggca caggcacatt aagcttattc ggataccaaa tgcggtttga
     5521 tctgcaaaaa gggtttcctt tgttaacaac gaaacgagta ccttttggat tgatcaaaag
     5581 cgaattgctt tggtttttaa aaggagatac gaatatccgc tatctattac aaaataaaaa
     5641 ccatatttgg gatgaatggg catttgaacg ctacatcaaa agtccagact ataatggacc
     5701 agatatgact gattttggcc atagatgttt gacagatcct gaattcaatg aagaatataa
     5761 aaagcagagc aagctttttt gcgagaagat cctaaccgat gattcctttg ctgaaacata
     5821 cggcgatctt ggacacatct acggctatca atggcgtcac tgggaaacaa aagacggtgg
     5881 ctttatcgat caaatcaaac aagtgatcga agcaatcaaa aagactcctg attctagaag
     5941 attgatcgtt tctgcatgga atccggaaga tgttcctagc atggctttgc ctccttgtca
     6001 tacgatgttt caattttatg ttcaagaggg acggctaagc tgccaattgt atcaacgcag
     6061 tggggatgtg tttctaggcg ttccgttcaa cattgcaagt tatgcgttgc tgactcacct
     6121 aattgcacat gaaacaggtt tagcggttgg cgaatttgtt cacacattag gagatgctca
     6181 tctttatatc aatcatatcg aacaaatgaa agaacaattg agccgagaaa tacgcgcatt
     6241 tccgacttta gttttgaatc aggaaaagca gtcagtattt gattttgaga tggaagatat
     6301 ccaattagaa ggatatgacc cacatccggc gatcaaagct cctatcgctg tttagaatca
     6361 gaaaggatga gaaaatgtta gctgcaattt gggcacagga tgaaaacgga ttgattggaa
     6421 aagaagaccg tcttccttgg cgtttgccaa atgatctgaa attcttcaaa caaatgacag
     6481 aagcaaatac actagtgatg ggacgaaaaa cattcgaagg gatgggtagc cgtccgttgc
     6541 cgaatcgtca gacgattgtt ttgacgagag attcttccta taaagcagaa ggcgtgcatg
     6601 tcatgcatag tgtggaagac gtgcttgctc tggaaaaaga aacagacggt atctttttca
     6661 tcgctggagg gtcagctgtt tatcaagaat ttctgccatt ttgtacgata ttataccgta
     6721 cagtcatcca tcatgtattc gatggagatg cttattttcc acctgttgac tggtctgatt
     6781 ggtcactgat caatactagt caaggagaaa tggatgaaaa aaatcgttat ccgcatcaat
     6841 ttgaaacgta tcagcgtaat gagaatcctg taaaaagcgg gacaggcgaa ttgacgatat
     6901 aaaaaagcta tggatagact agctgttatt tagagctgtc ccatccatag ctttattttt
     6961 tttattaagt aaagaataaa acagagaagt acataaaacc tgcacctaac ataacaaaca
     7021 aatgccaaac aacatgcata tagcggatag aattcaagct ataaaagaat gcgcctatcg
     7081 tgtaagaaag cccgcctgct accatcaaaa taacaccagt cattccaaga gagtgataaa
     7141 gaggaacagc agccacgaca cagagccacc ccataaaaat atagatgatc gtagatactt
     7201 ttgatactct ctcccgttta tgcaacgtca acgctttata tataatgcca agaatcgcaa
     7261 acaaccagat taatacaaat aaagtccaac ctagccatcc tcggatactc agcaaacaaa
     7321 aaggagtata acttcctgca atcaaaagaa aaatcgaact atgatcgaat acttggaaca
     7381 ccttttttgc ttttgtaaaa atcaatgaat gaaacaaagt agacgttaaa aataaaagaa
     7441 tcatcatcga tccatagata gcataagaga caatatggag ggaggaatgc aagtgggcac
     7501 cttttactaa aagaaccact agtcccgcga tactcaatcc agtcccaatt ccatgggtga
     7561 ctgcattaaa cacttcattt aatatttcat acgttcgatt aaatttcgtt ttttccatga
     7621 aaacggctcc tttactaggt gtaattaatg aaaaatcatt atttgtctgt tatactaaaa
     7681 atagaaattg tcttacatgt agtttaacat gaataaggca tcttgttaaa gaaagagaga
     7741 gagaaaataa tgacaaatgt aaaaatcgta acagattctt catgtacgat ggaaaaaaat
     7801 gtacgcgatg ctttaggcat tcgtgtcatg ccgctatcca tcatgatcga cggaacagta
     7861 tatcccgatg atgaccaact agacggcgaa agatttatgg aaatgatggc gaaagcaaaa
     7921 aatctgccca aaacaagcca accaccaatt ggagaattca tctcgatgta tgatgagcta
     7981 ggagaagacg gcagtgaagt gatttcgatc catatgacaa aaggcttgag tggaacagta
     8041 gaagcagcaa gacaagccag taatctaaca aaaacgaaag taacggttat cgacagtgat
     8101 accactgacc aaggattatc ttttcaggta attcgagcag ctgaattagc aaaagaaggt
     8161 aaaacagtag agaaaatcct tgaagaagtc aaaaaagtac aagacaatac aaaattatac
     8221 atcggaatat ccacactaga taacttggta aaaggtggaa gaatcagccg aacaactggt
     8281 ttgctgtcta gtgttttgaa catacgcgtg gtgatgaatt tcgcccattc tgaattaatc
     8341 cctgtaacta aggggcgagg aaagaaaacg ttcgataaat ggtttaataa tttgaaaaat
     8401 gaactgaaag aattgccaaa tgtgcgacaa atcggtattt cacatgcgga tgcaaaagaa
     8461 ttggcgcaag aattcaaaga gggtttgcaa gaattattcc cggacatgca tatccctgta
     8521 ctgcatacga atccggttat cgctacgcat actggtaaag acgcgtttgc aatcatgtat
     8581 tatgtagatt agtcgaaaag aggataagcc ctcagcctga aaggcttgca gcttattctc
     8641 tttttcttta taaaattagg aaaataattg ttttcttttt tcataaagac tacctttttg
     8701 ataaaatttt tgataacatt agaaccaatc gaatacaaga ggtgaaaaaa tgaaattaac
     8761 gaaacgacat ttgatcctcg ttttgt
//
LOCUS       DADVXV010000244         6145 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.guided.122, whole genome shotgun sequence.
ACCESSION   DADVXV010000244 DADVXV010000000
VERSION     DADVXV010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.guided.122"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            33..2387
                     /locus_tag="KB969_003041"
     CDS             33..2387
                     /locus_tag="KB969_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBB6870928.1"
                     /translation="MLTIGVGFALILFAVFGFLKLGFLGILIANGFRIIAGNTYQILC
                     LLLAVLGFWIVIKNTEFSIGKNRRWFGGILFYFGILLLLHAHLFGKLHTGEPNIMGTT
                     WDLLASDIKQSQVDNNVGGGMIGAILYHFTYFLIAQPGSYLAAVLLLAGGAFLFSNLE
                     GYQLLNGIQSIGERVQELLEGDPAKQARKQAAKEERMKQRAEAKEARRLAAKEAAEYE
                     KKKAVSQQRENTADEWQEPENTEPEQLSFVPIDSFQENIHPANLEKPVPDTPKQTNTA
                     EGFSDELPEDDGTSLEFEIEAEQENQDYELPTVDLLDSIPTVDQSDEYKKIEKNIGVL
                     EQTFQSFGVDAKVVKASLGPSVTKFEVQPAVGVKVSKIVNLTDDIALALAAKDVRMEA
                     PIPGKSLIGIEVPNGKISMVSFREIIEAQPNHPDKLLEVPLGRDVSGRVQTADLSKMP
                     HLLVAGSTGSGKSVAINGIITSILMRAKPHEVKLMMIDPKMVELNMYNGIPHLLTPVV
                     TNPRKAAQALQKVVQEMEERYEKFAATGVRNISGYNEFVQQKNLENGTKHPTLPFIVV
                     IVDELADLMMVASNEVEDAIIRLAQMARAAGIHMILATQRPSVDVITGIIKANVPSRM
                     AFAVSSGTDSRTIIDSNGAEKLLGRGDMLFLPMGENKPIRVQGAFISDHEVERVVQFV
                     TDQQEAHYEEKMMPTDEVETTGAPEQPQDELFEEAKALVVEMQTASISLLQRRFRIGY
                     NRAARLVDELEAHGVVGPSEGSKPRKVFIEQEETSETLPDDNDM"
     gene            2617..3684
                     /gene="rlmN"
                     /locus_tag="KB969_003042"
     CDS             2617..3684
                     /gene="rlmN"
                     /locus_tag="KB969_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBB6870929.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(3877..4980)
                     /locus_tag="KB969_003043"
     CDS             complement(3877..4980)
                     /locus_tag="KB969_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBB6870930.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            5532..6080
                     /gene="aac(6')"
                     /locus_tag="KB969_003044"
     CDS             5532..6080
                     /gene="aac(6')"
                     /locus_tag="KB969_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBB6870931.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2031 a         1063 c         1326 g         1725 t
ORIGIN      
        1 aaacgaaaaa gcaaaaacag cagcaggaac aaatgctgac gattggtgtt gggtttgcct
       61 tgattttatt tgctgtcttc ggctttttaa aattaggttt tttaggaata ttgattgcaa
      121 acggctttcg gatcattgca ggaaatactt accaaatcct ctgtctttta ttagccgtat
      181 taggattttg gattgtcatt aagaatacag agttttcaat tggtaaaaac cgacgctggt
      241 ttggcggcat actcttttat ttcggtatct tattattgtt acatgcccat ttatttggca
      301 aactccatac tggggaacca aatatcatgg ggacgacatg ggatttgtta gccagtgata
      361 taaaacaaag tcaagtagac aataacgttg gtggtgggat gattggagca atcctttatc
      421 attttactta cttcttgatt gcacagcctg gaagttattt agcagcagtg ctattactgg
      481 caggaggagc attcctgttc agtaatctgg aaggctatca gctgttaaat ggtatccaat
      541 caattggaga acgagtacag gaattattgg aaggtgatcc tgccaagcaa gctcgaaagc
      601 aagcggcaaa ggaagagaga atgaaacagc gcgcagaagc gaaagaagca aggcgcttag
      661 ctgcaaaaga agctgcagaa tatgagaaga aaaaagcggt gagccagcaa agggaaaata
      721 ctgctgatga atggcaggaa ccagaaaata cagagccgga gcagctaagt tttgttccaa
      781 tcgacagttt tcaagaaaat atccatcctg cgaatctaga gaaaccagta ccagatacac
      841 caaaacagac caatacagca gaaggttttt cagatgagtt gccagaggat gacggtacct
      901 cattagaatt tgagattgaa gcagaacagg aaaatcaaga ctatgaatta ccgacagttg
      961 atttgcttga ttctatacca actgtggatc aaagtgatga gtataaaaaa attgaaaaaa
     1021 atatcggcgt attagaacaa actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag
     1081 ccagcttagg accatccgtc acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa
     1141 gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga
     1201 tggaagcacc gattccaggt aaatcactga ttggtattga agtaccaaat ggaaagatca
     1261 gtatggtttc ctttagagaa atcatcgaag cacaaccaaa ccacccagat aaattactag
     1321 aagtaccttt aggacgtgat gtttctggac gggtacaaac ggctgatctt tcgaagatgc
     1381 ctcacttact cgtggctggt tcgactggta gtgggaagtc agtagcaatt aatgggatta
     1441 tcacaagtat attaatgcgt gctaagcccc atgaagtaaa actgatgatg atcgatccga
     1501 aaatggttga attgaatatg tacaacggca tacctcatct gttgacgccg gtcgtgacga
     1561 accctagaaa agcagcgcaa gccttacaaa aagtagtaca agaaatggaa gaacgatatg
     1621 aaaaattcgc ggcaaccgga gtaagaaata tttctggtta caatgaattt gttcaacaga
     1681 aaaacttgga aaacggaacg aaacatccaa ccttaccatt catcgtagtg atcgtagatg
     1741 aattagctga tttgatgatg gtagccagca atgaagttga agatgcgatt attcgtttag
     1801 cgcaaatggc tcgggcagcg gggattcata tgatcctagc tactcaacgt ccaagtgtgg
     1861 atgttatcac aggaatcatc aaagcaaatg taccttccag aatggcattt gcggtatcaa
     1921 gcggtacaga ttctcggacg atcattgatt ctaatggggc agaaaagctc ttagggcgag
     1981 gagatatgct attcttgcca atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca
     2041 tttctgacca cgaagtagaa cgggtcgttc aatttgttac agatcagcaa gaagctcatt
     2101 atgaagagaa aatgatgccg acagatgaag ttgaaacgac aggtgctcca gaacagccac
     2161 aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt
     2221 cccttctcca aagaagattt cggatcggtt acaaccgagc agcacgttta gtagatgaac
     2281 tggaagctca tggagttgtt ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg
     2341 agcaggaaga aacatcagaa acgttgccgg acgataatga catgtaaaac ttgtgtgatg
     2401 aagggttgaa aaacgaataa ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa
     2461 tggttttttt ccatcttttc taatacggta tgatgtcttg tctttttagt ttttgtgaga
     2521 ttaaagttct attcgattta tttgtgaagt attgcattaa ggaaatgaat catgtatagt
     2581 atgtagcgaa actttgagaa aaagagggaa aatactttgg aaaaacagtc catttatggc
     2641 ttgacgaatg aagaattaat caattggttt atagaaaacg gcgagaaaaa attccgagct
     2701 gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat
     2761 ctatcgaaac aattgatcga aaaattatcg gagcatttta tcatcaatcc tctaaaacag
     2821 atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt tgtttgaact ccctgataaa
     2881 aacatgattg agactgtact gatgagacaa gaatatggct tgtcagtttg tgtgacgaca
     2941 caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt
     3001 gatctgactg ctggagaaat tgttgcacag atcatgatgg tccaacatta ttttgatgag
     3061 cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg ggatcggtga gccatttgat
     3121 aattacgaca atgtaatgga ctttttgcat atcatcaatg atgccaaagg attggcaatt
     3181 ggtgctcggc acattacagt ttccactagt ggattagcac acaaaatcaa ggaattcgct
     3241 aataacggct tgcaagtcaa tctggctatt tccttgcacg cgccgaataa tgaggtgcga
     3301 acatcgatca tgcggatcaa ccgaagtttc ccaattgaga aattgatgga agctgtggat
     3361 gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta
     3421 aatgatagac cagagcatgc gcaacaatta gcagatctat taaaagataa gaaaaaatta
     3481 gcatatgtca acttgattcc atataatcca gtcagtgaac atgatcaata ttctcgcagt
     3541 ccaaaagctg atgtattgag attttatgat gtattgaaga aaaacggcgt aaactgtgtg
     3601 atacgtaaag aacatggtac agatattgat gcagcttgcg gacaattgcg aagcaagcaa
     3661 atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt ttttcaatta ccataaaagg
     3721 agcagttttc ttaattaagg aactgttcaa cttaaataag agaaaagatt ctatagcgaa
     3781 agctataaag ctttttttga caagaaaaac cctcatcaag caaagaaatg tcctcaattt
     3841 gatgacagcc tgcttgatgg gggttttagc aattatttaa ctgattttct tatatccttg
     3901 ctggctttct tgtgtagcat gataagtttc tacgtcaaga atggcctgtt taaatttttc
     3961 tcgggtgatt tcataaggca catgtttaat atcatttgtt gccatggctt tatctaagat
     4021 tgcttctaaa tcggtcgtga cattgagatt catgtcggtt aacgatactg gaagttggtt
     4081 ctttttcata aacacataga ttttatcaaa caaatcgaac tgctgatcca tcatcaataa
     4141 ggtcagtaca ccataactga cagatgctcc gtgaaggtat ccctccattt tttctagaac
     4201 agtcgtaccg taatagaatg agtgtgccat agcagaatta tagttattgt taactaaaac
     4261 agaaaccaat ccggtagtaa caatgatatc cgaaacgact tgttcaattg catatgaggg
     4321 acgatcgtcg gcactatctt tcaatgcttg cgtaccataa gtcaagagac gatcaatgca
     4381 catttttccg atttggattc ctaatctatc cgtgtagcct agatcatcgc cacgagcaga
     4441 aaaagtagat tcgacttctt tggataaagc atcgccaata cctgcccata agtatttatc
     4501 aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa
     4561 gaagagtccg tccattacgc cttcttcgtt atagatgaca cataccgcag tgacgggcga
     4621 acagttcgaa ccaatagtgg gaaaggtgaa gactggttta gctagttttt caccaatgac
     4681 ttttacagta tcgcaagcac ggccaccacc gactgcaaac aggacgtctg ctttttggac
     4741 actttcatgc tggatcaact gttcaatatt tccataagtt gaattacccc cgtaccagag
     4801 actggcgaca acctctattt cctgtgtcaa agctactttt attttgtttt ctgcctttga
     4861 aagtgcagtc ttccctccaa tcagcactac ttttgtccca tattctttga cgattccatt
     4921 tgctttttca tacgcatctg ttccaatggt ataatttggt aagaaaacac tttgactcat
     4981 attcatttcc ttctttcttc gttgaaacgg gttaaaattt taaagagtga tcgatctgac
     5041 tgcggctgta gatggagtag aggtgaacct aagacaggat aagtgatgaa taaggtggca
     5101 tgaacacctt gaaatcatca ataagtatcc taaaaacgaa caagtacaaa aacattgaaa
     5161 acgacaataa tgaatttttg ttcctcttag tatttctacc gattcccttt gcttttttgt
     5221 aattatctaa aaattctaaa aattaagatt attatatgaa aacaggtttt atttgtcaat
     5281 tcataattgg ttttttttaa agcaaaagat aatctatatc atgatgaaca aacagagttt
     5341 tttcctccaa ttgatggctt tcctgatctt tcctattttg aataaagtgt ttctgtataa
     5401 ttttttattt tataagtaag ataaataatg aaagaataga gatactgatt ggtagctaaa
     5461 gatttttgag cgagaacatt tcgttttttc aaaaggactg ttagaataag caagaacaag
     5521 ggggaagacg tatgataatc agtgaatttg accgtaataa tccagtattg aaagatcagc
     5581 tttctgattt actgagactg acttggccgg aagaatatgg agacagctcg gcagaagaag
     5641 tagaagaaat gatgaatcca gaacgaatcg cggtagcagc ggtagaccaa gatgagttag
     5701 taggatttat tggtgcaatc cctcaatacg gtatcacagg ttgggaattg catccattag
     5761 ttgtagaaag ctcccgacga aagaaccaaa taggtactcg attagtcaat tacttagaaa
     5821 aagaagtagc ttccagagga ggaatcacga tttatttagg tacggatgat ttagaccatg
     5881 gaacaacgtt aagtcaaacg gacctgtatg agcatacatt tgataaagtg gcttccatcc
     5941 agaaccttcg tgaacatccg tatgaattct atgaaaaatt aggttataaa atcgtaggtg
     6001 tcttaccaaa tgcaaatggc tgggacaaac cggatatttg gatggcaaaa acgattattc
     6061 ctcgaccaaa ttctcaataa taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat
     6121 aagaaggaat ttacgaaaat tactt
//
LOCUS       DADVXV010000245         4702 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.guided.142, whole genome shotgun sequence.
ACCESSION   DADVXV010000245 DADVXV010000000
VERSION     DADVXV010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.guided.142"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            194..1000
                     /locus_tag="KB969_003045"
     CDS             194..1000
                     /locus_tag="KB969_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HBB6870932.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            1018..1725
                     /locus_tag="KB969_003046"
     CDS             1018..1725
                     /locus_tag="KB969_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBB6870933.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWLFLHTP
                     LTIIQRRGHEVKEFPEPNSDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKII
                     GQVFADKEPQALYKITNGSIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKC
                     KICYPLPESVDIQEENQ"
     gene            1722..2693
                     /locus_tag="KB969_003047"
     CDS             1722..2693
                     /locus_tag="KB969_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HBB6870934.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVSHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            2686..3714
                     /gene="vanB"
                     /locus_tag="KB969_003048"
     CDS             2686..3714
                     /gene="vanB"
                     /locus_tag="KB969_003048"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HBB6870935.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKAAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            3720..4328
                     /locus_tag="KB969_003049"
     CDS             3720..4328
                     /locus_tag="KB969_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HBB6870936.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(4394..4567)
                     /locus_tag="KB969_003050"
     CDS             complement(4394..4567)
                     /locus_tag="KB969_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870937.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT         1329 a          986 c         1245 g         1142 t
ORIGIN      
        1 gatagaatga ttttctatca gtcctagaaa ttatagagcc gattttgacc gacaggtata
       61 accctgccgg tctttttttg ctgctacagg aaaactacag actggctaca gggaaagtac
      121 agatgcgctt gccataataa caatcgtacc agccacaaat cgtagtttta ttgcaaagga
      181 ggcattcgat caaatggaaa aaagcaacta tcattccaat gcggatcatc acaaacggca
      241 tatgaaacaa tccgtggaaa agcgggcttt tctatgtgcg ttcattattt cgttcacagt
      301 ctgcacgctg tttttggggt ggagactggc ttccgtattg gaggcaacac agataccgcc
      361 catccctgca actcatacag gcagcagcac tgacgtagtg gagaatttgg aggaaaacgc
      421 tcttgccacc gccaaagaac agggagatga acaggaatgg agcctgattt tagtgaacag
      481 gcagaacccc atccccgcac agtacgatgt ggagcttgag caactatcaa atggtgagcg
      541 gatagatatt cggatttctc cctatcttca agatttgttt gatgccgcaa gaactgatgg
      601 agtttacccg attgtcgcat ccggataccg aacaacagaa aaacagcaag aaattatgga
      661 tgaaaaaatt gccgaatata aggcgaaagg ctacacctct gcacaggcta aagcggaagc
      721 agaaacttgg gtggccgtgc cgggaacgag cgagcatcag cttggtcttg ctgtggatat
      781 caatgcggac ggaattcatt caacaggcaa cgaggtttat agatggctgg atgaaaacag
      841 ctatcgtttt ggttttattc gtcgctaccc accagacaag acagagataa ccggtgtgag
      901 caacgagccg tggcattacc gatatgttgg catcgaagct gccacagaga tgtacaacca
      961 aggggtttgc cttgaggaat atttaaaacc agaaaaatga gaaaaggatg ttatgttatg
     1021 gacagaaaaa gattgacaca gcgtttcccg ttcctgcttc caatgagacg ggcgcagaga
     1081 aaaatgtgct tttatgcggg aatgagattt gacggctgtc gctatgcgca gacgataggg
     1141 gaaaaatcgc tttcccattt gctctttgaa acggattgcg cattatacaa ccacaatacc
     1201 ggatttgaca tgatatacca ggaaaacaag gtgttcaact taaagctggc agcaaagacc
     1261 ttaaacggct tattgataag accgggggaa accttttctt tctggttgtt cctgcatacg
     1321 ccattgacaa ttatccagcg cagaggtcac gaagtaaagg agtttccaga gccaaacagt
     1381 gacgagatta aaggggtgga tgcaaccatt tcagagggct ggattgattt aaaagtgcga
     1441 aacgataccg actgcaccta ccaaatatgg gtgaccttag atgatgagaa aatcatcggt
     1501 caggtgttcg ccgacaaaga gccccaagca ttatacaaaa ttacaaatgg cagtatccag
     1561 tatgtccgtg aaagtggcgg gatttatgaa tatgcccagg ttaaacggat gcaagttgcc
     1621 ttaggtaccg gggaaataat agattgcaag ctgctttata caaacaaatg caaaatctgt
     1681 tatcccctcc cggaaagtgt ggatattcag gaggagaacc aatgagaaaa agtgtgggca
     1741 ttactgtttt tggatgcgaa caggatgagg caaatgcttt ccgcgcttta tcgccggatt
     1801 ttcatattat ccctacgctg attagcgatg cgatatcggc agacaacgca aaattggccg
     1861 ctggcaatca atgcgttagc gtaagccata agtccgaggt ttccgaggcg acaattcttg
     1921 cgctgagaaa ggtcggggta aaatacattt ctacccgcag catcggctgc gatcacattg
     1981 atacgactgc cgccgagaga atgggaatct cggttggcac ggttgcgtat tcgccggaca
     2041 gcgttgcgga ttatgctttg atgctgatgc tgatggccat acggggtgca aaacccacca
     2101 tgcacgccgt ggcgcaacaa gatttcagat tggatcgtat ccgggggaaa gaactggggg
     2161 atatgactgt gggagttatt ggaaccggcc atatcgggca agcggtcgtc aaaaggctgc
     2221 ggggatttgg atgccatgtg ctggcctatg ataacagccg aaaaatggat gcagattatg
     2281 tccagcttga tgagcttcta aaaaacagcg atattgttac gctccatgtg ccgctttgtg
     2341 cggatacccg ccatctgatc ggtcagaagc aaattggaga gatgaagcaa ggcgcatttt
     2401 taatcaacac cgggcgcgga gcgcttgtcg ataccggggc gctggtggag gcgttggaaa
     2461 gcggaaagct gggtggtgcg gcactggatg tgttggaggg cgaggatcag tttgtttata
     2521 ccgattgctc gcagaaagtg cttgaccatc cctttttgtc gcagctttta aggatgccga
     2581 atgtgatcat cacaccccat acggcgtact acactgagcg tgtgctgcag gatactacag
     2641 aaaaaacaat caggaattgt ctcaattttg aaaggagttt acagcatgaa tagaataaaa
     2701 gtcgcaatca tcttcggcgg ttgctcggag gaacatgatg tgtcggtaaa agccgcaata
     2761 gaaattgctg cgaacattga tacggaaaaa ttcgatccgc actacatcgg aattacaaaa
     2821 aacggtgtat ggaagctatg caagaagcca tgtacggaat gggaagccga cagtctcccc
     2881 gccatactct ccccggatag gaaaacgcat gggctgcttg tcatgaaaga aagcgaatac
     2941 gaaacacggc gtattgatgt ggctttcccg gttttgcatg gcaaatgcgg ggaggatggt
     3001 gcgatacagg ggctgtttgt attgtctggt atcccctatg tgggctgtga tattcaaagc
     3061 tccgcagctt gcatggacaa atcactggcc tacattctta caaaaaatgc gggcatcgcc
     3121 gttcccgaat ttcaaatgat tgataaaggt gacaagccgg aggcgggtgc gcttacctac
     3181 cctgtctttg tgaagccggc acggtcaggt tcgtcctttg gcgtaaccaa agtaaacggt
     3241 acggaagaac ttaacgctgc gatagaagcg gcaggacaat atgatggaaa aatcttaatt
     3301 gagcaagcga tttcgggctg tgaggtcggg tgtgcggtca tggggaacga ggatgatttg
     3361 attgtcggcg aagtggatca aatccggctg agccacggta tcttccgcat ccatcaggaa
     3421 aacgagccgg aaaaaggctc agaaaatgcg atgattacag ttcccgcaga cattccggtc
     3481 gaggaacgaa atcgggtgca ggaaacggca aagaaagtat atcgggtgct tggatgcaga
     3541 gggcttgccc gtgttgatct ttttttgcag gaggatggcg gcatcgttct aaatgaggtc
     3601 aataccctgc ccggttttac atcgtacagc cgctacccac gtatgatggc cgccgcagga
     3661 atcacgcttc ctgcactgat tgacagcctg attacattgg cgttaaagag gtgataagta
     3721 tggaaaatgg ttttttgttt ttagatgaaa tgttgcatgg cgtccgttgg gatgccaagt
     3781 acgccacatg ggataacttc acaggaaaac cggtggatgg gtatgaggtg aatcgcatca
     3841 tcggcacaaa ggccgtggcg tttgctctgc gcgaggcaca aatccatgcg gctgcgcttg
     3901 gctatggctt gcttttatgg gatggatatc ggccaagaac tgcggtggac tgcttcctgc
     3961 gttgggcagc gcaaccggag gacaatctca caaaagaaaa attttacccc aatatagagc
     4021 gagccgagtt gattacaaag ggttatgtgg cctcacaatc cagccatagc cgtggaagcg
     4081 caattgatct tacgctctac cacctggata caggggaact tgtttcaatg ggaagtaact
     4141 tcgattttat ggacgaacgg tcgcatcata cagcaaaagg gataggggat gcagaggcac
     4201 aaaatcgaag atgcttgcgt aaaatcatgg aaagcagcgg atttcagtct tatcgctttg
     4261 aatggtggca ctataagttg attgatgagc cataccccga tacctatttt aattttgccg
     4321 tttcataatg aaagtattgg ttttgtatca gattttggat ttgataaaat ctatgctggt
     4381 catggacaat cttttactgg aaagtggtta aagcatcttt tgtaatacat tgcaaattat
     4441 agtattcaat ctgcccagcg gcagaaaaga aaaaaaccgc tgttgggcag acctttccca
     4501 cgcccatttt gtattttgct ggcggcggtt ttgagaaatc aaggccgccg ttcttttctg
     4561 gcagcaaaag gtgtggcggc ccataggagg atgccgctat gctgttttgc tattgccatg
     4621 ctctaatcca cttccaccac tcaaaaaaag ccttgcccct ccatgaactg aaccccaaaa
     4681 gttgaactat ttaatggact gt
//
LOCUS       DADVXV010000246         4224 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.guided.153, whole genome shotgun sequence.
ACCESSION   DADVXV010000246 DADVXV010000000
VERSION     DADVXV010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.guided.153"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            174..1652
                     /gene="msr(C)"
                     /locus_tag="KB969_003051"
     CDS             174..1652
                     /gene="msr(C)"
                     /locus_tag="KB969_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBB6870938.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            1699..2145
                     /locus_tag="KB969_003052"
     CDS             1699..2145
                     /locus_tag="KB969_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBB6870939.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2344..2859)
                     /locus_tag="KB969_003053"
     CDS             complement(2344..2859)
                     /locus_tag="KB969_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBB6870940.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            2976..4178
                     /locus_tag="KB969_003054"
     CDS             2976..4178
                     /locus_tag="KB969_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBB6870941.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1257 a          712 c          920 g         1335 t
ORIGIN      
        1 ttttttcgaa cgacagtaga ataggtgaaa gctatgacag atttggtgat ttagtcatag
       61 ttatttcgtt cagagtagga aaagatgtga tgcagttttt ttgcaaacag atttttctgc
      121 tcttttttag tatcgataat tgttgtttta catgaaatag gagtgtaaaa catatggaaa
      181 atttagcagt aaatataaca aatctacaag tcagctttgg caaccagcta gaactatcta
      241 ttgattctct tcgtgtctat cagcaagatc gtatagggat cataggagaa aatggtgtcg
      301 gtaaatcgac tttgctcaaa ctaatagccg gtgaactttt tcccgatcat gggaaaatcc
      361 aaacagagat caccttcaac tacctgcctc aattaaccta tctcgctgaa gcaaaggacc
      421 taaatttgga attagccagt catttccagt taagactgga agaaacttca gagcggaaat
      481 ggagcggagg ggaagaacga aagatcgagt tgatacgtct tctttcttct tatgaacaag
      541 ggatgcttct agacgagcca acaacccatc tagatagaaa aagtattgat cgactgattg
      601 aagagcttcg ttattattat ggtacgctgg tttttgttag tcatgatcgc tattttctag
      661 atgagctagc atcgaaaatc tgggaagtaa aagacggaga aatccgagag ttttcgggga
      721 attatagtgc ctatctcact caaaaggaat tggagaaaaa gactcagcta cgagaagcag
      781 agtcgatcat gaaagagaaa aaacgattgg aaaaatcgat ccaagaaaag aaaaaacaag
      841 cggaaaagtt ggaaaaagtg tccagtaaaa agaaaaagca acaaatcaga ctggatcggt
      901 tgtcttcctc taaacaaaaa gacagtgtac aaaaagccat ccaaaagaat gcgaaaacat
      961 tagagagaag actccaaaaa ataggagaaa caaccaagcc gcagcagatg aaacaaatcc
     1021 gttttccagt accaaaatct cttgaactcc acagccgcta tcccatcatg ggacaaaatg
     1081 tccaattgga aagaagtggg agaacattac tggtaaatgg tgattttcag ttttctttag
     1141 gtaaaaaaat cgcgattgtc ggtgaaaatg gttcaggtaa gacaacctta ttagaacata
     1201 tccgcaaaca aggagaagga atccttctct ctccgaaagt aagctttcaa gtatatcagc
     1261 aaaagggtta tcaaatgaca tctgaagaat ccatcattcg ttttgtcatg agacaaacag
     1321 agttttcaga atcgcttgtc cgtagtttgc tgaatcactt agggtttgct caggaaactt
     1381 tgacgaaacc gttatgtaca ttaagtgggg gagaagcgac ccgtctgacg attgctttgc
     1441 tttttactaa gccaagtaat gtgttgctgt tagatgaacc gactaatttt attgatatgg
     1501 caacgatcga agctttagag aagctaatgc aaatatatcc gggaacgatt ttgtttactt
     1561 ctcatgattc ttactttgtc gagcgtacgg ctgatgaagt ttatgaaata aaagggcaga
     1621 aaataaaaaa agtacttacg agaaattttt aaatgtgcta cgatgatttt cgtgacaaat
     1681 ttaaaggagt ggtacagatt gcctacaaat aaaaaagaag gaataatttt tacaacaatg
     1741 atgtgttttt tgatggtctt ggggatgagc gcgtataatt tatggctgca tcaagatctt
     1801 catttatcaa gtttgttgat tggtctagtg cctggattcg tggtggcttt cattttggat
     1861 gtcttcatca tcggtgtgct ggcgaaaaaa attgccttta aactaccagt aaatccagaa
     1921 agcaaggtcc aaatgatctt aactatttca tgcttgatgg ttttaggaat ggtgacatgt
     1981 atgtctttat tcggtgtgat catggaacaa ggaatacctg atcaattatt ctctgcttat
     2041 atgaatgctt ggaaaatgaa tgtgattgcc gctttaccgt tgcagttgat catcgttggc
     2101 ccgctttcaa gaagtgtgct aaaagcaatt caaagtaatg aatgatggaa cactgttatt
     2161 tgaaaaaagg ccttggcatg ctttttgtca tagtctcttg aatgcagttc tagaaaaata
     2221 gtgatccgaa cgataggttt tggcctgtcg ttcggatcgc tttttctttt ccaactgtat
     2281 tgctctttta ttgaagataa tttgctcttc aatagatatt tctagaaagg ttctgtttat
     2341 cccttactca aaaaactgct gcatttgttc tcttacttgc tgacaccatt ggagttcctg
     2401 ctgacaaagc ataattctgc gctggatcac aacataacgt ccaaattctt gtttcttgtc
     2461 tagcgagagg tcattcaatt ttttttgatt tttttgcatg attttgttca gctgttgttc
     2521 tctagtgaat agcagtccag tagctgttgt tttatcgagc gtcgaaaaag catagatttt
     2581 tgctagaaat tcatcttttt gcgtaggagc gggagtttcc tctttgatcc attcctctac
     2641 aagagcacgt ccttcatcag tcaagtggta gatctttttt tgagagtgct cgtctttgtc
     2701 caaaacggtc acataaccct gctggtctaa cttggcaagc gttgtataga tctgactgtg
     2761 atgggcttcc caaaaaattg tgatcagctg cttcaattca tacccagaac gtggtttgga
     2821 taaaagcacg cataataata tataggctaa agtattcata aaaatcctac ctctcgtctt
     2881 attttcttta ttatatcaca gtaaagtttc cacgttttac atgtgcatat tgacatgtaa
     2941 aataaatcat gtatgatgct aatagagaga aagggatgga aatattggag aatcaaatag
     3001 atatacaaga acaaacaaat gaagaaacaa aggggaaaag ttcagcgcta gttgtagcag
     3061 ctacctgtat gatcgctttt atgggagtgg gtctagtaga cccaatctta aaaacgattg
     3121 ctgcacagtt aaacgctacg ccagctgaaa cgaccctgtt atttactagt tacatgttag
     3181 tcactggtgt ggtgatgcta tttacaggtt tcttatctag tcggatcggt ttgaaaaaaa
     3241 cattgatgac aggattgttt atcatcgttg tattcgctgg tcttggcgga ttatctggga
     3301 atatcggaat gctgattggg ttacgtgccg gctggggtgt cgggaatgct ttatttgtct
     3361 ctactgcttt agcaacgatc gtcagtattt tagttggtaa cacagaaaaa gcaatcatga
     3421 tgtatgaagc agcacttggc tgcggaatgg ctgttggccc tctagtcggt ggggtcttgg
     3481 gcagtggttc atggcgttat ccattttttg gggtagcatt tttgatgttt tgcggtttta
     3541 tagccctagc ggtactttta cctgaaactg agaaaccaaa gagaaaagta ggcctttggg
     3601 aaggtgtcaa agcgttaagc aatcataaac ttcgttcagt tggactaatc gcattgttat
     3661 ataatttcgg attctttact ttacttgcgt atgcgccatt tttattgatt ggctattctg
     3721 aattagaagt cggttttgta ttttttggct ggggtgtgct tctggctatt gcttcgattt
     3781 tcgttgcacc ggctcttgag cggaagttta cgacttatcg gacaatttta gcagcatttg
     3841 tcttattcat tatttgtttg ctgttattag gagctggaac ttctatgcca gtccttgtac
     3901 cgatcagcat tgtgttagca ggatttttcc aaggaattat caatacactg ttgacgacga
     3961 ttgctatgga aataccaggt ctgcaacgaa acgttgcttc gtccagctat agttttgtcc
     4021 gctttttcgg tggagcttta gcaccattta ttgcaggtgt gattggtgaa catattggtg
     4081 aaagctatgc gttttatttt gcaggtgcca ttgttcttat cagtgtatgt tgtatcattt
     4141 atcaccgtaa ttattttgct acaaatgaag aagaataaga aatcagaggt tgtgaaaaag
     4201 ctgtcctgca tcaagtcata agaa
//
LOCUS       DADVXV010000247         4010 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.guided.156, whole genome shotgun sequence.
ACCESSION   DADVXV010000247 DADVXV010000000
VERSION     DADVXV010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.guided.156"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            86..778
                     /locus_tag="KB969_003055"
     CDS             86..778
                     /locus_tag="KB969_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBB6870942.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSWKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1105..1602
                     /gene="dfrG"
                     /locus_tag="KB969_003056"
     CDS             1105..1602
                     /gene="dfrG"
                     /locus_tag="KB969_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBB6870943.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1674..3626)
                     /locus_tag="KB969_003057"
     CDS             complement(1674..3626)
                     /locus_tag="KB969_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBB6870944.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3633..3869)
                     /locus_tag="KB969_003058"
     CDS             complement(3633..3869)
                     /locus_tag="KB969_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBB6870945.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT         1345 a          682 c          675 g         1308 t
ORIGIN      
        1 catatgtaat ttaaaaacgc ttgacattgt gtttgagatc acttactttt agcatgtaaa
       61 agtattggat taaggagcta tgcaaatgaa aaagaaattt attactggtg ggattgtcgt
      121 tgcatttcta tgtctaattg gctacacagg cacgcggtac gcaaatgaaa ttattttgtg
      181 gggtggagag acagatattg atacaatcaa tgagaatctg acacagcttg atcatacatt
      241 gacagataaa gagcaagcga ttacagatct taccgctcga ctagcacaaa aagaacagac
      301 attgcaagat tcaaaggcag atgtccaaga ataccaaaca aaagtaaatg aattagaaaa
      361 ccaaaaaaat caatcggcag cagaaaaaca aaacttagaa agtcaattag tcagcaagga
      421 tgcacaacta caaagcaaac aaaatgaaat caatgtcaaa ctagatgaga tcaaccaaaa
      481 aaatgatgaa atcaatcatc tgaatgcaga ttggacagca agactacaag aagcacaagc
      541 aaaactttca gaattacaaa atactgtaaa tggtttgaat caacaaatcg caacactgac
      601 acaagaaaaa acaaatgtag aaactcagtt aacagataca caaaagaaat tagacgaagc
      661 aactgctgaa aactcaagct ggaaacaata tattcaaaag ttagaaaaag caaaagatga
      721 agtggaagat acagctgata aatctcagca aattgttgaa gaacatttgc gtaaataatc
      781 tttcttaaca agtaaaccta aattagtaaa gaagcaacag taatctatac taagtagttc
      841 agttttggag tacaaaatga caaaatgtac ttcaaaatgg actacttttt tcattttaac
      901 ttacatacca aattacatac aaaatgattt ataaaatgca attgaaaatg ataattgaat
      961 gaaaatttgt gattttgtgg tattatgata atataactta tagaaaaaat tgcttattca
     1021 actaacgggc aggataatga gaaaaggttt tttgatagaa ataagaaatt agatggtaaa
     1081 ttagttaaaa aggctgtgtt ataaatgaaa gtttctttga ttgctgcgat ggataagaat
     1141 agagtgattg gcaaagagaa tgacattcct tggaggattc ccaaggactg ggaatatgtt
     1201 aaaaatacta caaagggaca tccgataata ttaggtagga agaaccttga atcaatcgga
     1261 agagccttac ctgacagaag aaatattatt ctgacgagag ataaggggtt tacctttaat
     1321 ggttgtgaaa ttgttcattc aatagaagat gtttttgagt tatgtaaaaa cgaagaagaa
     1381 atttttattt tcggaggaga acagatttat aatttgtttt tcccttatgt tgagaaaatg
     1441 tacatcacaa aaatacatca tgaattcgaa ggagatactt tttttccaga agtgaattat
     1501 gaggaatgga atgaggtatt tgcccaaaaa gggataaaga atgataaaaa tccgtataac
     1561 tactattttc atgtatatga aagaaaaaac ttattgagtt aacgggtgcg ttaattgaag
     1621 aagaacagta aagataaagc acaagagctt gggattactc caagctcttt ttgtcatttg
     1681 aaataaatta tatctttcca atcaaattgt ttatctgtaa tccctaatct ttgagcaggt
     1741 gtcaaaacct ttttatccgc tgatttaaaa gggcgacaaa agttgtagta agttcttaga
     1801 attgtaatcg caaattgagc atacttcgga ttgaagttag cgtaaatata gctcttctta
     1861 tcaccacgag ctgttgttaa tggtctttca agagatgata tataacgtct tatctgttga
     1921 ataaagctat tggtcgaatg gtcattaaca tttaatagca tctttgcgat ttcgtttggt
     1981 tccagagcag ataaatccgt tctacaatca actgaataaa atcctttatc cttagtggct
     2041 aatggatgtt tgatagggtt atcggcatat ttgcgatatc tttctccatc tttactaata
     2101 gcctcttcgt ggaattgatg acttgttagt aattcagtta gataatgaga tgccaaagtc
     2161 cgtagaaact ttgttttgaa tcctctgata tctccccaat cgagcagttc tgcttttgct
     2221 tgtccgaatt cttttaagca ttgttttctg cttttcgtct tgttaacttg gcaaataaaa
     2281 tgatgtgcat cgctcaacct taattctttc gtgaatactc tataaaaggc gtttctaata
     2341 gagaagtcat catcactaat cattcgccat tcgtcggcat taaccatttg tttaattaac
     2401 caatagtgag cagttgtagt ataaggagca tcaacattta aaccatcgac aaatctactc
     2461 ctattagtaa ttttccctaa ttcgtgaaga taagcattcc tattttcgct atcgttagcg
     2521 gatggttctt gtggataata agaccaatct aacctatcat ttttacgact aaaagtattg
     2581 agatggtctt ctttgaattt tcttgtatct tcatttaatt catccattga aatattccaa
     2641 tcataggcaa catcagaacg gaacacatat cttgataaga cctcagcaga tacaactata
     2701 tacgtttgca tattaaggtc ttcaaacccc gtatatttct ttgaaccttg tcctttctta
     2761 cggacgttat ttaggtagta gtgcatcttg tccgtattaa gccacatctc gttaaatttc
     2821 tttgtttgaa ggggttgtgt ctcatatcgt tctaaaaact ccaaacaacg cctatacagc
     2881 cactccagct tatgatagta ggttccaact ccaattccta aaatatcaca agtacgactg
     2941 actgaaaccc ttccaacaac catcttagcg aacattggaa gaatggtgtt cttttgttgg
     3001 tgataagtag tggtttcttc tctttttggt agaacattag tgaacttctt acacgcctta
     3061 cattgatagc gttgagattt gcccctactt ttcccccttt tgtaaaattg cttcggctca
     3121 ttgaatgggg ttgattcttc ttccgagcag ccttctttat gaaattgata atctggctca
     3181 acatcttgga tgctattgat ttctataagg cgtttaattt cttcaacaac agaccaatta
     3241 gataaagggg ttactgtaca gttttgcgat acacctctgc caataggatt gtcattgcag
     3301 tacatacctt tatgaccttt atctttggaa ctaccagtca ttttatatcg acttggtttc
     3361 ccttttacat ctttgaattt gtgctgttct ttcccaaaat tacaacaaaa cggattgatg
     3421 cagtaattat attgaatggg atattcagaa ccgttccatt taaaagacgt tggcaagaac
     3481 aacattttgt tataccttgt tgcaaatcgt tttggagtta ataaatcata ttgtttagcc
     3541 ctatctttta attcttcgtt tgaaatcgga attttaacat ctacaatttc atcttccttc
     3601 gtggctaatc ttttaagctt ggtcattgtc tatcaaccca ctctatcttt gatacccatt
     3661 ttttcaacaa tccgcttatt acttcgcttg ttggcaatcc attcaataaa cttcttatcg
     3721 tctaaaatgt tcaataagaa ttcatccact gcttcgcttt cagtacgctc tgcatattca
     3781 gcgtattgct taactatcac ccttacttgc tctgatattt cccaatccac agacttagcg
     3841 ttcttatttt ttggctcaag aaattgcata ggaaaatgca cccctttttg cttagtaaat
     3901 tgtaaccatt ttaacacacc aatttgcatt cctacaataa ttatttcacg ttcgcatttt
     3961 tatatacatt ttaacttaca ttttgtggtg taaattaaca acaaacgttg
//
LOCUS       DADVXV010000248         2771 bp    DNA     linear   BCT 15-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate 303989-18
            SAMEA8426474-rid11941713.guided.178, whole genome shotgun sequence.
ACCESSION   DADVXV010000248 DADVXV010000000
VERSION     DADVXV010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8426474
            Sequence Read Archive: ERR5555439
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001005887.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001005887.1
            Genome Coverage       :: 146x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/15/2021 09:53:05
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,063
            CDSs (total)                      :: 2,997
            Genes (coding)                    :: 2,927
            CDSs (with protein)               :: 2,927
            Genes (RNA)                       :: 66
            rRNAs                             :: 1, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 28 of 70
            Pseudo Genes (incomplete)         :: 33 of 70
            Pseudo Genes (internal stop)      :: 16 of 70
            Pseudo Genes (multiple problems)  :: 6 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8426474-rid11941713.guided.178"
                     /isolate="303989-18"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2018-08"
     gene            110..193
                     /locus_tag="KB969_003059"
     CDS             110..193
                     /locus_tag="KB969_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBB6870946.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="KB969_003060"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="KB969_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBB6870947.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1318..2181)
                     /locus_tag="KB969_003061"
     CDS             complement(1318..2181)
                     /locus_tag="KB969_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBB6870948.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2183..2455)
                     /locus_tag="KB969_003062"
     CDS             complement(2183..2455)
                     /locus_tag="KB969_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBB6870949.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2472..2681)
                     /locus_tag="KB969_003063"
     CDS             complement(2472..2681)
                     /locus_tag="KB969_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBB6870950.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          487 c          443 g          990 t
ORIGIN      
        1 ttatttgata gtagatttaa aactttgcaa cagaaccaaa attttgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac cgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaattt
     1081 ggaaagttac acgttactaa agggaatgta gataaattat taggtatagg gcacctctaa
     1141 taactaccaa ttaattcacc tcaaaatgaa attagaaaaa aacagcgaaa tttttaaatc
     1201 tatttcttat cgatacaaat tcctcgtagg cgctcgggac cccaacatga ggaaatgttt
     1261 ttataaaaaa agagtagtta ccgttttttg gtaactactc ttttcctttt ttaaggttta
     1321 aatacctgga agtttaggtg ttttgggtat tggtggtgta ggtagctgca agctttccat
     1381 tttttgttga attgctttaa attcaggggt ttcttggtgt tgattttgaa ccattttttg
     1441 ctctattctc tccaaagtcg gttgaatttc tttccctgat actttacgat ttaattctct
     1501 ttctaaggtc tctttcggac taatggaagg cgtttctaag cttgaataga gtttcactcc
     1561 ttctctattg taaagcctta tatcgctaaa taagcccgtt ttatgaaggg tttctaaatt
     1621 ggtcggtaag tttttgacaa caatatcatg cgcttgtttt ggtgttgccc tagctgtcat
     1681 tggatcatct gcatacatgg tttcatatcg ttcaatcgtt cctaagtatg attcaatttt
     1741 cggtactgcc atgacgtata tttttgtttc ataaccttta gattgaagca ttgtggctgt
     1801 ttgaatggga acgtctgttg ttcgtcctgt tccttcaatc actaaattat agccttgatc
     1861 gcttaaacgg ctaataagtg cttctgtcat gcgattcgaa taaggggtaa cgtgttttac
     1921 tacgtctttt tcatagagtt tcactaattc gtcaaaattt gggtgctgtt gtttaaaggt
     1981 atcattatca atgacaataa cattcccttg tgtttcttca aaaattgctg atcgcaaact
     2041 ggttttccct gaccctggtt gcccaccaag taaaaaagcg gttggcgatt caaccgctag
     2101 tctattttta gttagtcgtt caacattctt ttctaaacga tcttcaaatt gcttttcggt
     2161 gaagtcagta atattcgcca tgttaagcca ctttctcttt attcaaaatt tgttttgaat
     2221 attgattcat tgaccgccaa tactcatgaa tagcttgtaa ttcttcaaat ggttgttgaa
     2281 ataaatcaac ttcttgtgcc acttctaatt gatttaaaag attcacttct agtaaacgag
     2341 tatttttagt atctagttca tgattcaaaa cataatttaa tacccgatta taaacacttg
     2401 ccgataactc attaatgatt tcaatttcaa atgttttttc atacgtaact gccatttcat
     2461 tttcactcct tttaaagttt gtcaggtaaa tatttccgta tatattcttc taaggcttga
     2521 tccataactt cttttacgtt tccgccattc tttgctgttt cgatttttat gatatggtgc
     2581 aagtcggcac gaacacgaac cgtcttatcc cccattatat ctttttttgc gctgattggc
     2641 gtatcatttc gttttgcttt ctgtgcgcct aaatttccca cgatcgctca cttctttcta
     2701 tttcttctta ctatttattt tatcatcacc tatcacaaat cacaagtgat ttgtgattaa
     2761 tcacttgtga t
//
